Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1002
• Symbol:CDH4
• Description:cadherin 4

DataSource: http://genomecrispr.dkfz.de/#!/results/CDH4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
61928302	61928325	20	+	26472758	Jiyoye	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	1.4207219133438214	[52]	[106]	8	hSpCas9	negative selection	28489
61928285	61928308	CHR_HSCHR20_1_CTG2	+	26472758	Jiyoye	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000280641	1.4207219133438214	[52]	[106]	8	hSpCas9	negative selection	28490
61923518	61923541	20	-	26472758	Jiyoye	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	-1.1116979287575102	[191]	[66]	-6	hSpCas9	negative selection	28491
61923497	61923520	CHR_HSCHR20_1_CTG2	-	26472758	Jiyoye	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000280641	-1.1116979287575102	[191]	[66]	-6	hSpCas9	negative selection	28492
61933043	61933066	20	+	26472758	Jiyoye	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	1.077607224416379	[141]	[225]	7	hSpCas9	negative selection	28493
61933028	61933051	CHR_HSCHR20_1_CTG2	+	26472758	Jiyoye	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000280641	1.077607224416379	[141]	[225]	7	hSpCas9	negative selection	28494
61772999	61773022	20	+	26472758	Jiyoye	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	-0.41594685641004725	[68]	[38]	-3	hSpCas9	negative selection	28495
61844784	61844807	20	+	26472758	Jiyoye	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.25105617958859155	[77]	[69]	2	hSpCas9	negative selection	28496
61852750	61852773	20	+	26472758	Jiyoye	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.8096128440050836	[229]	[303]	5	hSpCas9	negative selection	28497
61895037	61895060	CHR_HSCHR20_1_CTG2	-	26472758	Jiyoye	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000280641	0.18129397408954573	[206]	[176]	1	hSpCas9	negative selection	28498
61895037	61895060	20	-	26472758	Jiyoye	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.18129397408954573	[206]	[176]	1	hSpCas9	negative selection	28499
61910430	61910453	CHR_HSCHR20_1_CTG2	+	26472758	Jiyoye	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000280641	-0.32534430762914057	[107]	[64]	-2	hSpCas9	negative selection	28500
61910430	61910453	20	+	26472758	Jiyoye	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	-0.32534430762914057	[107]	[64]	-2	hSpCas9	negative selection	28501
61910566	61910589	CHR_HSCHR20_1_CTG2	+	26472758	Jiyoye	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000280641	0.2605828838941848	[206]	[186]	2	hSpCas9	negative selection	28502
61910566	61910589	20	+	26472758	Jiyoye	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.2605828838941848	[206]	[186]	2	hSpCas9	negative selection	28503
61910597	61910620	CHR_HSCHR20_1_CTG2	-	26472758	Jiyoye	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000280641	-0.10393808932801774	[237]	[166]	0	hSpCas9	negative selection	28504
61910597	61910620	20	-	26472758	Jiyoye	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	-0.10393808932801774	[237]	[166]	0	hSpCas9	negative selection	28505
61928302	61928325	20	+	26472758	KBM7	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.05687242222944497	[486,334]	[203,192]	0	hSpCas9	negative selection	219607
61928285	61928308	CHR_HSCHR20_1_CTG2	+	26472758	KBM7	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000280641	0.05687242222944497	[486,334]	[203,192]	0	hSpCas9	negative selection	219608
61923518	61923541	20	-	26472758	KBM7	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.05958082429438577	[386,447]	[308,115]	0	hSpCas9	negative selection	219609
61923497	61923520	CHR_HSCHR20_1_CTG2	-	26472758	KBM7	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000280641	0.05958082429438577	[386,447]	[308,115]	0	hSpCas9	negative selection	219610
61933043	61933066	20	+	26472758	KBM7	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.14521827711056423	[941,545]	[477,288]	1	hSpCas9	negative selection	219611
61933028	61933051	CHR_HSCHR20_1_CTG2	+	26472758	KBM7	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000280641	0.14521827711056423	[941,545]	[477,288]	1	hSpCas9	negative selection	219612
61772999	61773022	20	+	26472758	KBM7	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	1.178793424490085	[242,145]	[329,88]	9	hSpCas9	negative selection	219613
61844784	61844807	20	+	26472758	KBM7	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	-0.09906880709897758	[310,147]	[114,81]	-1	hSpCas9	negative selection	219614
61852750	61852773	20	+	26472758	KBM7	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	-0.16543615910993448	[1163,726]	[436,345]	-2	hSpCas9	negative selection	219615
61895037	61895060	CHR_HSCHR20_1_CTG2	-	26472758	KBM7	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000280641	-0.2428766616777045	[1117,1129]	[391,499]	-2	hSpCas9	negative selection	219616
61895037	61895060	20	-	26472758	KBM7	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	-0.2428766616777045	[1117,1129]	[391,499]	-2	hSpCas9	negative selection	219617
61910430	61910453	CHR_HSCHR20_1_CTG2	+	26472758	KBM7	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000280641	0.3120813037647988	[285,193]	[127,146]	3	hSpCas9	negative selection	219618
61910430	61910453	20	+	26472758	KBM7	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.3120813037647988	[285,193]	[127,146]	3	hSpCas9	negative selection	219619
61910566	61910589	CHR_HSCHR20_1_CTG2	+	26472758	KBM7	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000280641	0.13129174849397374	[593,890]	[390,392]	1	hSpCas9	negative selection	219620
61910566	61910589	20	+	26472758	KBM7	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.13129174849397374	[593,890]	[390,392]	1	hSpCas9	negative selection	219621
61910597	61910620	CHR_HSCHR20_1_CTG2	-	26472758	KBM7	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000280641	1.1096887261871227	[817,753]	[1126,503]	9	hSpCas9	negative selection	219622
61910597	61910620	20	-	26472758	KBM7	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	1.1096887261871227	[817,753]	[1126,503]	9	hSpCas9	negative selection	219623
61928302	61928325	20	+	26472758	Raji	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	1.8607435677904742	[69]	[58]	9	hSpCas9	negative selection	410725
61928285	61928308	CHR_HSCHR20_1_CTG2	+	26472758	Raji	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000280641	1.8607435677904742	[69]	[58]	9	hSpCas9	negative selection	410726
61923518	61923541	20	-	26472758	Raji	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.5224210346524433	[119]	[39]	5	hSpCas9	negative selection	410727
61923497	61923520	CHR_HSCHR20_1_CTG2	-	26472758	Raji	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000280641	0.5224210346524433	[119]	[39]	5	hSpCas9	negative selection	410728
61933043	61933066	20	+	26472758	Raji	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.5587171638754332	[470]	[160]	5	hSpCas9	negative selection	410729
61933028	61933051	CHR_HSCHR20_1_CTG2	+	26472758	Raji	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000280641	0.5587171638754332	[470]	[160]	5	hSpCas9	negative selection	410730
61772999	61773022	20	+	26472758	Raji	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.37402919475977225	[132]	[39]	3	hSpCas9	negative selection	410731
61844784	61844807	20	+	26472758	Raji	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.9147384574312035	[127]	[55]	8	hSpCas9	negative selection	410732
61852750	61852773	20	+	26472758	Raji	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.5259876496726357	[403]	[134]	5	hSpCas9	negative selection	410733
61895037	61895060	CHR_HSCHR20_1_CTG2	-	26472758	Raji	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000280641	0.32342046167022387	[519]	[150]	3	hSpCas9	negative selection	410734
61895037	61895060	20	-	26472758	Raji	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.32342046167022387	[519]	[150]	3	hSpCas9	negative selection	410735
61910430	61910453	CHR_HSCHR20_1_CTG2	+	26472758	Raji	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000280641	0.6890709040618948	[146]	[54]	6	hSpCas9	negative selection	410736
61910430	61910453	20	+	26472758	Raji	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.6890709040618948	[146]	[54]	6	hSpCas9	negative selection	410737
61910566	61910589	CHR_HSCHR20_1_CTG2	+	26472758	Raji	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000280641	0.5317892171866385	[306]	[102]	5	hSpCas9	negative selection	410738
61910566	61910589	20	+	26472758	Raji	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.5317892171866385	[306]	[102]	5	hSpCas9	negative selection	410739
61910597	61910620	CHR_HSCHR20_1_CTG2	-	26472758	Raji	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000280641	0.719313083695025	[423]	[161]	6	hSpCas9	negative selection	410740
61910597	61910620	20	-	26472758	Raji	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.719313083695025	[423]	[161]	6	hSpCas9	negative selection	410741
61928302	61928325	20	+	26472758	K562	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	-0.8987062144321505	[359]	[162]	-5	hSpCas9	negative selection	601843
61928285	61928308	CHR_HSCHR20_1_CTG2	+	26472758	K562	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000280641	-0.8987062144321505	[359]	[162]	-5	hSpCas9	negative selection	601844
61923518	61923541	20	-	26472758	K562	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	1.2789571463709257	[226]	[464]	9	hSpCas9	negative selection	601845
61923497	61923520	CHR_HSCHR20_1_CTG2	-	26472758	K562	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000280641	1.2789571463709257	[226]	[464]	9	hSpCas9	negative selection	601846
61933043	61933066	20	+	26472758	K562	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.6564348749700537	[477]	[635]	5	hSpCas9	negative selection	601847
61933028	61933051	CHR_HSCHR20_1_CTG2	+	26472758	K562	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000280641	0.6564348749700537	[477]	[635]	5	hSpCas9	negative selection	601848
61772999	61773022	20	+	26472758	K562	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.24441872766644668	[270]	[270]	1	hSpCas9	negative selection	601849
61844784	61844807	20	+	26472758	K562	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.2010912960023462	[168]	[163]	1	hSpCas9	negative selection	601850
61852750	61852773	20	+	26472758	K562	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	-0.004053383964454982	[827]	[696]	0	hSpCas9	negative selection	601851
61895037	61895060	CHR_HSCHR20_1_CTG2	-	26472758	K562	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000280641	0.6123592203106454	[863]	[1114]	5	hSpCas9	negative selection	601852
61895037	61895060	20	-	26472758	K562	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.6123592203106454	[863]	[1114]	5	hSpCas9	negative selection	601853
61910430	61910453	CHR_HSCHR20_1_CTG2	+	26472758	K562	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000280641	0.32571882976829514	[206]	[218]	2	hSpCas9	negative selection	601854
61910430	61910453	20	+	26472758	K562	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.32571882976829514	[206]	[218]	2	hSpCas9	negative selection	601855
61910566	61910589	CHR_HSCHR20_1_CTG2	+	26472758	K562	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000280641	0.03420102027610117	[648]	[560]	0	hSpCas9	negative selection	601856
61910566	61910589	20	+	26472758	K562	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.03420102027610117	[648]	[560]	0	hSpCas9	negative selection	601857
61910597	61910620	CHR_HSCHR20_1_CTG2	-	26472758	K562	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000280641	-0.2641306575355413	[477]	[335]	-2	hSpCas9	negative selection	601858
61910597	61910620	20	-	26472758	K562	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	-0.2641306575355413	[477]	[335]	-2	hSpCas9	negative selection	601859
61252557	61252580	20	-	26627737	DLD1	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.17740717126135852	[698]	[207,269,261]	1	hSpCas9	negative selection	815400
61773049	61773072	20	+	26627737	DLD1	viability	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.025335867966377768	[1280]	[484,267,417]	0	hSpCas9	negative selection	815412
61844768	61844791	20	-	26627737	DLD1	viability	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.673141166968183	[161]	[153,39,50]	6	hSpCas9	negative selection	815413
61852762	61852785	20	-	26627737	DLD1	viability	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.281374428628135	[1753]	[778,723,520]	3	hSpCas9	negative selection	815414
61873768	61873791	20	+	26627737	DLD1	viability	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.49417064588027154	[786]	[285,134,110]	-5	hSpCas9	negative selection	815415
61252557	61252580	20	-	26627737	GBM cells	viability after 5 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.39948418831646915	[175]	[118,129]	6	hSpCas9	negative selection	897715
61773049	61773072	20	+	26627737	GBM cells	viability after 5 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.19520830247886456	[474]	[252,191]	-3	hSpCas9	negative selection	897727
61844768	61844791	20	-	26627737	GBM cells	viability after 5 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	1.3410196173627003	[98]	[142,125]	9	hSpCas9	negative selection	897728
61852762	61852785	20	-	26627737	GBM cells	viability after 5 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.5922525366516336	[563]	[486,424]	8	hSpCas9	negative selection	897729
61873768	61873791	20	+	26627737	GBM cells	viability after 5 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.3789736590424658	[370]	[155,149]	-5	hSpCas9	negative selection	897730
61252557	61252580	20	-	26627737	GBM cells	viability after 13 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.16076376456164054	[175]	[87,121]	2	hSpCas9	negative selection	980030
61773049	61773072	20	+	26627737	GBM cells	viability after 13 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.03868655134162924	[474]	[267,236]	0	hSpCas9	negative selection	980042
61844768	61844791	20	-	26627737	GBM cells	viability after 13 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	1.2436012844645614	[98]	[167,93]	9	hSpCas9	negative selection	980043
61852762	61852785	20	-	26627737	GBM cells	viability after 13 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.8892140305791727	[563]	[627,516]	9	hSpCas9	negative selection	980044
61873768	61873791	20	+	26627737	GBM cells	viability after 13 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.7449562599672698	[370]	[134,107]	-7	hSpCas9	negative selection	980045
61252557	61252580	20	-	26627737	GBM cells	viability after 21 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.0637759542817213	[175]	[190,207]	9	hSpCas9	negative selection	1062345
61773049	61773072	20	+	26627737	GBM cells	viability after 21 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.7690114091544277	[474]	[152,149]	-6	hSpCas9	negative selection	1062357
61844768	61844791	20	-	26627737	GBM cells	viability after 21 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.9649695229821349	[98]	[116,93]	8	hSpCas9	negative selection	1062358
61852762	61852785	20	-	26627737	GBM cells	viability after 21 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	1.037725572514509	[563]	[615,640]	8	hSpCas9	negative selection	1062359
61873768	61873791	20	+	26627737	GBM cells	viability after 21 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.6260309903460763	[370]	[139,121]	-5	hSpCas9	negative selection	1062360
61252557	61252580	20	-	26627737	RPE1	viability after 9 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.536651179772838	[202]	[62,340]	8	hSpCas9	negative selection	1144660
61773049	61773072	20	+	26627737	RPE1	viability after 9 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	1.6192190755537084	[387]	[177,624]	8	hSpCas9	negative selection	1144672
61844768	61844791	20	-	26627737	RPE1	viability after 9 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.5363379312564851	[265]	[70,184]	3	hSpCas9	negative selection	1144673
61852762	61852785	20	-	26627737	RPE1	viability after 9 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.762914469659226	[2578]	[1294,1466]	5	hSpCas9	negative selection	1144674
61873768	61873791	20	+	26627737	RPE1	viability after 9 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.2654391254390666	[1185]	[290,331]	-2	hSpCas9	negative selection	1144675
61252557	61252580	20	-	26627737	RPE1	viability after 12 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	2.068178164946614	[202]	[150,310]	9	hSpCas9	negative selection	1226975
61773049	61773072	20	+	26627737	RPE1	viability after 12 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	1.9360302148537387	[387]	[377,420]	8	hSpCas9	negative selection	1226987
61844768	61844791	20	-	26627737	RPE1	viability after 12 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.9955024468920959	[265]	[107,178]	6	hSpCas9	negative selection	1226988
61852762	61852785	20	-	26627737	RPE1	viability after 12 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.8262142726476549	[2578]	[1330,1119]	5	hSpCas9	negative selection	1226989
61873768	61873791	20	+	26627737	RPE1	viability after 12 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.5956547988700738	[1185]	[222,197]	-4	hSpCas9	negative selection	1226990
61252557	61252580	20	-	26627737	RPE1	viability after 15 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	2.0825277922420145	[202]	[258,227]	8	hSpCas9	negative selection	1309290
61773049	61773072	20	+	26627737	RPE1	viability after 15 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	1.9672860203195808	[387]	[446,411]	8	hSpCas9	negative selection	1309302
61844768	61844791	20	-	26627737	RPE1	viability after 15 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	1.5067890401970463	[265]	[138,285]	7	hSpCas9	negative selection	1309303
61852762	61852785	20	-	26627737	RPE1	viability after 15 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	1.0596138582093775	[2578]	[1990,1066]	6	hSpCas9	negative selection	1309304
61873768	61873791	20	+	26627737	RPE1	viability after 15 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.021099754050374342	[1185]	[379,282]	0	hSpCas9	negative selection	1309305
61252557	61252580	20	-	26627737	RPE1	viability after 18 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.2647324453721973	[202]	[18,251]	7	hSpCas9	negative selection	1391605
61773049	61773072	20	+	26627737	RPE1	viability after 18 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	2.2450816651601926	[387]	[463,530]	9	hSpCas9	negative selection	1391617
61844768	61844791	20	-	26627737	RPE1	viability after 18 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	1.797377742421463	[265]	[249,248]	8	hSpCas9	negative selection	1391618
61852762	61852785	20	-	26627737	RPE1	viability after 18 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.8131411167489935	[2578]	[1335,1101]	5	hSpCas9	negative selection	1391619
61873768	61873791	20	+	26627737	RPE1	viability after 18 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.22336470185623009	[1185]	[336,206]	-1	hSpCas9	negative selection	1391620
61252557	61252580	20	-	26627737	HeLa	viability after 8 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.04311712485240563	[410]	[324,151,111]	0	hSpCas9	negative selection	1473920
61773049	61773072	20	+	26627737	HeLa	viability after 8 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.37481352478157337	[1213]	[802,198,313]	-4	hSpCas9	negative selection	1473932
61844768	61844791	20	-	26627737	HeLa	viability after 8 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	1.1193825566245807	[155]	[64,192,164]	8	hSpCas9	negative selection	1473933
61852762	61852785	20	-	26627737	HeLa	viability after 8 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.7488298987789961	[1033]	[802,829,652]	6	hSpCas9	negative selection	1473934
61873768	61873791	20	+	26627737	HeLa	viability after 8 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.5651587149064291	[464]	[169,116,130]	-5	hSpCas9	negative selection	1473935
61252557	61252580	20	-	26627737	HeLa	viability after 12 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.422981314461562	[410]	[147,85,150]	-4	hSpCas9	negative selection	1556235
61773049	61773072	20	+	26627737	HeLa	viability after 12 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-1.2771082881022673	[1213]	[361,164,102]	-8	hSpCas9	negative selection	1556247
61844768	61844791	20	-	26627737	HeLa	viability after 12 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	1.3975672524855842	[155]	[205,99,211]	8	hSpCas9	negative selection	1556248
61852762	61852785	20	-	26627737	HeLa	viability after 12 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.4922951034797911	[1033]	[842,556,414]	4	hSpCas9	negative selection	1556249
61873768	61873791	20	+	26627737	HeLa	viability after 12 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.5895421210970809	[464]	[10,143,222]	-5	hSpCas9	negative selection	1556250
61252557	61252580	20	-	26627737	HeLa	viability after 15 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.14983903278622895	[410]	[67,264,117]	-1	hSpCas9	negative selection	1638550
61773049	61773072	20	+	26627737	HeLa	viability after 15 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.35155316247218593	[1213]	[474,248,440]	-3	hSpCas9	negative selection	1638562
61844768	61844791	20	-	26627737	HeLa	viability after 15 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.561576087530158	[155]	[59,62,163]	4	hSpCas9	negative selection	1638563
61852762	61852785	20	-	26627737	HeLa	viability after 15 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.9006090627015879	[1033]	[632,680,1066]	6	hSpCas9	negative selection	1638564
61873768	61873791	20	+	26627737	HeLa	viability after 15 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.10694231773350138	[464]	[295,147,73]	-1	hSpCas9	negative selection	1638565
61252557	61252580	20	-	26627737	HeLa	viability after 18 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.1526312083514909	[410]	[42,221,117]	-1	hSpCas9	negative selection	1720865
61773049	61773072	20	+	26627737	HeLa	viability after 18 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.3364146378358306	[1213]	[325,206,440]	-3	hSpCas9	negative selection	1720877
61844768	61844791	20	-	26627737	HeLa	viability after 18 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.5711148542311507	[155]	[39,53,163]	4	hSpCas9	negative selection	1720878
61852762	61852785	20	-	26627737	HeLa	viability after 18 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.9189614165125322	[1033]	[436,572,1066]	7	hSpCas9	negative selection	1720879
61873768	61873791	20	+	26627737	HeLa	viability after 18 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.16306112570935405	[464]	[193,111,73]	-1	hSpCas9	negative selection	1720880
61252557	61252580	20	-	26627737	HCT116	viability after 6 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.2439031726286387	[769]	[267,296]	6	hSpCas9	negative selection	1803180
61773049	61773072	20	+	26627737	HCT116	viability after 6 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.0821856924918456	[1648]	[354,229]	0	hSpCas9	negative selection	1803192
61844768	61844791	20	-	26627737	HCT116	viability after 6 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	2.029086369440546	[308]	[477,43]	8	hSpCas9	negative selection	1803193
61852762	61852785	20	-	26627737	HCT116	viability after 6 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.8563656708027634	[2139]	[630,596]	5	hSpCas9	negative selection	1803194
61873768	61873791	20	+	26627737	HCT116	viability after 6 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.33813351308269823	[686]	[136,56]	-2	hSpCas9	negative selection	1803195
61252557	61252580	20	-	26627737	HCT116	viability after 8 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.633705546316345	[439]	[179,114,173]	-6	hSpCas9	negative selection	1885495
61773049	61773072	20	+	26627737	HCT116	viability after 8 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.5252655365645552	[466]	[389,400,320]	5	hSpCas9	negative selection	1885507
61844768	61844791	20	-	26627737	HCT116	viability after 8 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.4225239131279931	[140]	[96,88,125]	4	hSpCas9	negative selection	1885508
61852762	61852785	20	-	26627737	HCT116	viability after 8 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.9636160010999082	[577]	[563,730,567]	8	hSpCas9	negative selection	1885509
61873768	61873791	20	+	26627737	HCT116	viability after 8 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	1.0585928117768264	[277]	[261,276,415]	8	hSpCas9	negative selection	1885510
61252557	61252580	20	-	26627737	HCT116	viability after 9 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.1817437408828989	[769]	[297,181]	1	hSpCas9	negative selection	1967810
61773049	61773072	20	+	26627737	HCT116	viability after 9 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.020698010573298342	[1648]	[320,545]	0	hSpCas9	negative selection	1967822
61844768	61844791	20	-	26627737	HCT116	viability after 9 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.42512969245492305	[308]	[212,29]	3	hSpCas9	negative selection	1967823
61852762	61852785	20	-	26627737	HCT116	viability after 9 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.6428442894733761	[2139]	[789,972]	4	hSpCas9	negative selection	1967824
61873768	61873791	20	+	26627737	HCT116	viability after 9 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.3503349871816897	[686]	[101,176]	-2	hSpCas9	negative selection	1967825
61252557	61252580	20	-	26627737	HCT116	viability after 12 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.24764863483505972	[439]	[170,220,194]	-3	hSpCas9	negative selection	2050125
61773049	61773072	20	+	26627737	HCT116	viability after 12 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.6752626757255896	[466]	[436,318,413]	6	hSpCas9	negative selection	2050137
61844768	61844791	20	-	26627737	HCT116	viability after 12 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.8720038990320675	[140]	[105,116,185]	7	hSpCas9	negative selection	2050138
61852762	61852785	20	-	26627737	HCT116	viability after 12 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	1.5723887023346876	[577]	[1055,834,803]	9	hSpCas9	negative selection	2050139
61873768	61873791	20	+	26627737	HCT116	viability after 12 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	0.49029065324235926	[277]	[127,144,347]	5	hSpCas9	negative selection	2050140
61252557	61252580	20	-	26627737	HCT116	viability after 15 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.5070982565820098	[439]	[176,235,120]	-5	hSpCas9	negative selection	2132440
61773049	61773072	20	+	26627737	HCT116	viability after 15 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.6740199974055506	[466]	[453,495,337]	6	hSpCas9	negative selection	2132452
61844768	61844791	20	-	26627737	HCT116	viability after 15 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.3979031713563652	[140]	[161,73,90]	4	hSpCas9	negative selection	2132453
61852762	61852785	20	-	26627737	HCT116	viability after 15 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	1.1579353294374857	[577]	[754,826,642]	8	hSpCas9	negative selection	2132454
61873768	61873791	20	+	26627737	HCT116	viability after 15 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	0.9562917230496968	[277]	[292,216,415]	7	hSpCas9	negative selection	2132455
61252557	61252580	20	-	26627737	HCT116	viability after 18 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.12524114463741853	[439]	[380,153,162]	1	hSpCas9	negative selection	2214755
61773049	61773072	20	+	26627737	HCT116	viability after 18 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	1.0586822120961283	[466]	[622,474,304]	7	hSpCas9	negative selection	2214767
61844768	61844791	20	-	26627737	HCT116	viability after 18 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.6208710632524954	[140]	[69,88,158]	5	hSpCas9	negative selection	2214768
61852762	61852785	20	-	26627737	HCT116	viability after 18 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	1.1770285267511122	[577]	[763,461,682]	8	hSpCas9	negative selection	2214769
61873768	61873791	20	+	26627737	HCT116	viability after 18 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	1.0877438957939027	[277]	[309,223,328]	8	hSpCas9	negative selection	2214770
61697446	61697469	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATTAGCTGAGCGTGGTGGTGG	CDH4	ENSG00000179242	1.0062115233457334	[153,25]	[71,3]	4	dCas9-VP64	positive selection	2399683
61499238	61499261	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCTGACTGCCTGACGCTGAGG	CDH4	ENSG00000179242	-1.282911973902948	[206,187]	[19,14]	-7	dCas9-VP64	positive selection	2415564
61499264	61499287	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGGTTGGGGGCACAGCCCCGG	CDH4	ENSG00000179242	-1.445741416344529	[80,3]	[2,2]	-8	dCas9-VP64	positive selection	2415565
61499288	61499311	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCAGAGTGAGCAGCATGAAGG	CDH4	ENSG00000179242	0.09843832866659663	[32,39]	[5,9]	0	dCas9-VP64	positive selection	2415566
61599602	61599625	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTCAGCAGCGCAGGCAGGCGG	CDH4	ENSG00000179242	-1.5812833410900065	[95,180]	[8,10]	-8	dCas9-VP64	positive selection	2415567
61599653	61599676	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCACTCTGTGTCTTTCACTGG	CDH4	ENSG00000179242	-1.3478360629032493	[230,305]	[10,35]	-7	dCas9-VP64	positive selection	2415568
61599631	61599654	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGACAGGGCTATTGTCTTGGAGG	CDH4	ENSG00000179242	0.12714954348464635	[22,8]	[2,2]	0	dCas9-VP64	positive selection	2415569
61328288	61328311	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCAGCCTCCCGAGTAGCTAG	CDH4	ENSG00000179242	0.5805591546882161	[16,8]	[5,1]	2	dCas9-VP64	positive selection	2421347
61619239	61619262	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGGGGCTGGGGCTGGGGCTAG	CDH4	ENSG00000179242	4.687211381256624	[18,3]	[129,1]	9	dCas9-VP64	positive selection	2427184
61545964	61545987	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGGAGG	CDH4	ENSG00000179242	1.250295307438589	[24,5]	[12,2]	5	dCas9-VP64	positive selection	2434544
61631567	61631590	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCCCCGAG	CDH4	ENSG00000179242	-1.2513288674205318	[297,436]	[21,46]	-7	dCas9-VP64	positive selection	2446507
61529861	61529884	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTATGTCACCCAGG	CDH4	ENSG00000179242	0.6554256480809371	[58,1089]	[28,388]	3	dCas9-VP64	positive selection	2456399
61654028	61654051	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGGCAGAGGCTGCAATCTTGG	CDH4	ENSG00000179242	-2.3011193462997337	[203,500]	[9,20]	-9	dCas9-VP64	positive selection	2462529
61620187	61620210	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGATGGATGGATGGATGGACAG	CDH4	ENSG00000179242	2.7644531499590617	[51,2]	[77,0]	8	dCas9-VP64	positive selection	2471287
61918944	61918967	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAGCCTTGACCTCCCAGG	CDH4	ENSG00000179242	-0.13547020725059378	[412,709]	[41,189]	0	dCas9-VP64	positive selection	2474486
61918944	61918967	CHR_HSCHR20_1_CTG2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAGCCTTGACCTCCCAGG	CDH4	ENSG00000280641	-0.13547020725059378	[412,709]	[41,189]	0	dCas9-VP64	positive selection	2474487
61697446	61697469	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATTAGCTGAGCGTGGTGGTGG	CDH4	ENSG00000179242	-0.08593954762364797	[86,223]	[25,66]	0	dCas9-VP64	positive selection	2494938
61499238	61499261	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCTGACTGCCTGACGCTGAGG	CDH4	ENSG00000179242	0.15641197427711406	[103,120]	[33,45]	1	dCas9-VP64	positive selection	2510819
61499264	61499287	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGGTTGGGGGCACAGCCCCGG	CDH4	ENSG00000179242	-0.22512915428335645	[51,24]	[11,8]	-2	dCas9-VP64	positive selection	2510820
61499288	61499311	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCAGAGTGAGCAGCATGAAGG	CDH4	ENSG00000179242	0.6153570826591016	[32,58]	[15,28]	4	dCas9-VP64	positive selection	2510821
61599602	61599625	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTCAGCAGCGCAGGCAGGCGG	CDH4	ENSG00000179242	0.15398008829558674	[180,229]	[50,95]	1	dCas9-VP64	positive selection	2510822
61599653	61599676	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCACTCTGTGTCTTTCACTGG	CDH4	ENSG00000179242	-0.8426566895775878	[181,440]	[54,56]	-7	dCas9-VP64	positive selection	2510823
61599631	61599654	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGACAGGGCTATTGTCTTGGAGG	CDH4	ENSG00000179242	1.3771554863500326	[44,426]	[122,267]	7	dCas9-VP64	positive selection	2510824
61328288	61328311	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCAGCCTCCCGAGTAGCTAG	CDH4	ENSG00000179242	0.21208715000527545	[37,95]	[24,24]	1	dCas9-VP64	positive selection	2516602
61619239	61619262	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGGGGCTGGGGCTGGGGCTAG	CDH4	ENSG00000179242	0.7843109750104308	[123,86]	[55,62]	5	dCas9-VP64	positive selection	2522439
61545964	61545987	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGGAGG	CDH4	ENSG00000179242	0.8668431868856517	[26,20]	[22,6]	6	dCas9-VP64	positive selection	2529799
61631567	61631590	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCCCCGAG	CDH4	ENSG00000179242	0.4244343490827851	[184,278]	[65,133]	3	dCas9-VP64	positive selection	2541762
61529861	61529884	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTATGTCACCCAGG	CDH4	ENSG00000179242	0.32671661568011956	[247,62]	[91,37]	2	dCas9-VP64	positive selection	2551654
61654028	61654051	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGGCAGAGGCTGCAATCTTGG	CDH4	ENSG00000179242	0.04959992004292818	[112,68]	[26,33]	0	dCas9-VP64	positive selection	2557784
61620187	61620210	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGATGGATGGATGGATGGACAG	CDH4	ENSG00000179242	-0.745179068402318	[185,151]	[42,22]	-7	dCas9-VP64	positive selection	2566542
61918944	61918967	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAGCCTTGACCTCCCAGG	CDH4	ENSG00000179242	0.2584978845854493	[172,83]	[35,62]	2	dCas9-VP64	positive selection	2569741
61918944	61918967	CHR_HSCHR20_1_CTG2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAGCCTTGACCTCCCAGG	CDH4	ENSG00000280641	0.2584978845854493	[172,83]	[35,62]	2	dCas9-VP64	positive selection	2569742
61910597	61910620	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.19596224279231256	[5,4]	[4,4]	4	hSpCas9	positive selection	2978089
61852840	61852863	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGTTGATGAACTCAGGGCGG	CDH4	ENSG00000179242	-0.8222620039743814	[3,3]	[1,0]	-8	hSpCas9	positive selection	2978090
61910431	61910454	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.13298629588107141	[3,3]	[4,1]	3	hSpCas9	positive selection	2978091
61910445	61910468	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGCGACCACGGTCTCCACGCGG	CDH4	ENSG00000179242	0.22017642400799126	[3,2]	[2,3]	5	hSpCas9	positive selection	2978092
61910597	61910620	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.48959218955058625	[5,5]	[5,5]	8	hSpCas9	positive selection	3045947
61852840	61852863	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGTTGATGAACTCAGGGCGG	CDH4	ENSG00000179242	-0.13113928724201443	[3,3]	[3,0]	-2	hSpCas9	positive selection	3045948
61910431	61910454	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.20005035655815345	[3,3]	[2,2]	3	hSpCas9	positive selection	3045949
61910445	61910468	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGCGACCACGGTCTCCACGCGG	CDH4	ENSG00000179242	-0.44468656020225034	[3,3]	[1,1]	-6	hSpCas9	positive selection	3045950
61252557	61252580		-	24336571	A375	resistance to PLX after 7 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.07561031290470632	[2,2]	[2,2]	2	hSpCas9	positive selection	3104509
61254843	61254866		+	24336571	A375	resistance to PLX after 7 days	TACAACTAGAGAGACCTGCAAGG	CDH4	ENSG00000179242	-0.46800288898536524	[8,6]	[4,5]	-9	hSpCas9	positive selection	3104510
61773097	61773120		+	24336571	A375	resistance to PLX after 7 days	TGAGGCGGCGCAAACGGGACTGG	CDH4	ENSG00000179242	-0.31856918791652783	[11,9]	[8,8]	-8	hSpCas9	positive selection	3104511
61773088	61773111		-	24336571	A375	resistance to PLX after 7 days	TTTGCGCCGCCTCAGCCCGTTGG	CDH4	ENSG00000179242	0.00938887929927551	[15,17]	[14,17]	0	hSpCas9	positive selection	3104513
61252557	61252580		-	24336571	A375	resistance to PLX after 14 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.4645736268663372	[2,2]	[1,1]	4	hSpCas9	positive selection	3162302
61254843	61254866		+	24336571	A375	resistance to PLX after 14 days	TACAACTAGAGAGACCTGCAAGG	CDH4	ENSG00000179242	-0.9738971065594726	[9,7]	[1,1]	-9	hSpCas9	positive selection	3162303
61773097	61773120		+	24336571	A375	resistance to PLX after 14 days	TGAGGCGGCGCAAACGGGACTGG	CDH4	ENSG00000179242	0.2970869076012631	[7,5]	[3,3]	3	hSpCas9	positive selection	3162304
61773088	61773111		-	24336571	A375	resistance to PLX after 14 days	TTTGCGCCGCCTCAGCCCGTTGG	CDH4	ENSG00000179242	-0.7401178675562731	[20,22]	[5,5]	-8	hSpCas9	positive selection	3162306
61252557	61252580		-	24336571	A375	viability after 7 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.911983776228912	[6]	[2,2]	-8	hSpCas9	negative selection	3220095
61254843	61254866		+	24336571	A375	viability after 7 days	TACAACTAGAGAGACCTGCAAGG	CDH4	ENSG00000179242	0.14970680975939676	[6]	[8,6]	2	hSpCas9	negative selection	3220096
61773097	61773120		+	24336571	A375	viability after 7 days	TGAGGCGGCGCAAACGGGACTGG	CDH4	ENSG00000179242	0.23737029680276245	[9]	[11,9]	3	hSpCas9	negative selection	3220097
61773088	61773111		-	24336571	A375	viability after 7 days	TTTGCGCCGCCTCAGCCCGTTGG	CDH4	ENSG00000179242	0.09380611621742913	[16]	[15,17]	1	hSpCas9	negative selection	3220099
61252557	61252580		-	24336571	A375	viability after 14 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-1.1239928814594402	[6]	[2,2]	-8	hSpCas9	negative selection	3277888
61254843	61254866		+	24336571	A375	viability after 14 days	TACAACTAGAGAGACCTGCAAGG	CDH4	ENSG00000179242	0.38001476129845996	[6]	[9,7]	5	hSpCas9	negative selection	3277889
61773097	61773120		+	24336571	A375	viability after 14 days	TGAGGCGGCGCAAACGGGACTGG	CDH4	ENSG00000179242	-0.3651993422675687	[9]	[7,5]	-4	hSpCas9	negative selection	3277890
61773088	61773111		-	24336571	A375	viability after 14 days	TTTGCGCCGCCTCAGCCCGTTGG	CDH4	ENSG00000179242	0.4702822706975076	[16]	[20,22]	6	hSpCas9	negative selection	3277892
61252557	61252580	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	3.6668736985077737	[18,4]	[0,0]	9	hSpCas9	positive selection	3342328
61252508	61252531	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	1.3107543508990243	[87,34]	[0,0]	5	hSpCas9	positive selection	3342329
61254828	61254851	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.9353981165584727	[79,79]	[0,0]	4	hSpCas9	positive selection	3361561
61254816	61254839	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.06460188344152731	[159,159]	[0,0]	0	hSpCas9	positive selection	3361562
61910597	61910620	20	-	26780180	HT29	viability (Avana library 4 designs)	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	1.08965752639976	[]	[]	4	hSpCas9	negative selection	3414400
61852840	61852863	20	-	26780180	HT29	viability (Avana library 4 designs)	CCTGGTTGATGAACTCAGGGCGG	CDH4	ENSG00000179242	0.877532407066796	[]	[]	3	hSpCas9	negative selection	3414401
61910430	61910453	20	+	26780180	HT29	viability (Avana library 4 designs)	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	1.37478601894822	[]	[]	5	hSpCas9	negative selection	3414402
61910445	61910468	20	-	26780180	HT29	viability (Avana library 4 designs)	TTGCGACCACGGTCTCCACGCGG	CDH4	ENSG00000179242	0.0373712970183918	[]	[]	0	hSpCas9	negative selection	3414403
61910430	61910453	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	1.79782084113091	[]	[]	2	hSpCas9	negative selection	3490897
61852840	61852863	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGTTGATGAACTCAGGGCGG	CDH4	ENSG00000179242	1.85455640521902	[]	[]	2	hSpCas9	negative selection	3490898
61910445	61910468	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGCGACCACGGTCTCCACGCGG	CDH4	ENSG00000179242	6.06477103005202	[]	[]	9	hSpCas9	negative selection	3490899
61910597	61910620	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	1.23124769884123	[]	[]	1	hSpCas9	negative selection	3490900
61844753	61844776	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATTGACTCCATGTCCGGCCGG	CDH4	ENSG00000179242	3.40418165498807	[]	[]	5	hSpCas9	negative selection	3490901
61773135	61773158	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACGTGCCCGAGAACTCGCGCGG	CDH4	ENSG00000179242	2.32787898259049	[]	[]	3	hSpCas9	negative selection	3490902
61910430	61910453	20	+	26780180	A375	viability (Avana lentiGuide)	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	-3.7386003881503	[]	[]	-6	hSpCas9	negative selection	3599556
61852840	61852863	20	-	26780180	A375	viability (Avana lentiGuide)	CCTGGTTGATGAACTCAGGGCGG	CDH4	ENSG00000179242	8.15403046702909	[]	[]	6	hSpCas9	negative selection	3599557
61910445	61910468	20	-	26780180	A375	viability (Avana lentiGuide)	TTGCGACCACGGTCTCCACGCGG	CDH4	ENSG00000179242	6.78146112292026	[]	[]	5	hSpCas9	negative selection	3599558
61910597	61910620	20	-	26780180	A375	viability (Avana lentiGuide)	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	-0.196879229205515	[]	[]	0	hSpCas9	negative selection	3599559
61844753	61844776	20	+	26780180	A375	viability (Avana lentiGuide)	GCATTGACTCCATGTCCGGCCGG	CDH4	ENSG00000179242	-1.47863137455831	[]	[]	-2	hSpCas9	negative selection	3599560
61773135	61773158	20	+	26780180	A375	viability (Avana lentiGuide)	AACGTGCCCGAGAACTCGCGCGG	CDH4	ENSG00000179242	2.27175040195948	[]	[]	2	hSpCas9	negative selection	3599561
61910430	61910453	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.04115563202659106	[4]	[5,3]	1	hSpCas9	positive selection	3708215
61852840	61852863	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGTTGATGAACTCAGGGCGG	CDH4	ENSG00000179242	0.06758175236149327	[4]	[4,3]	1	hSpCas9	positive selection	3708216
61910445	61910468	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGCGACCACGGTCTCCACGCGG	CDH4	ENSG00000179242	0.5136709386882607	[4]	[5,6]	9	hSpCas9	positive selection	3708217
61910597	61910620	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.06902458501662384	[6]	[6,7]	1	hSpCas9	positive selection	3708218
61844753	61844776	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATTGACTCCATGTCCGGCCGG	CDH4	ENSG00000179242	0.34149007126758013	[5]	[7,6]	8	hSpCas9	positive selection	3708219
61773135	61773158	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACGTGCCCGAGAACTCGCGCGG	CDH4	ENSG00000179242	0.19535103683555446	[5]	[6,6]	5	hSpCas9	positive selection	3708220
61910430	61910453	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.07687157653113214	[5]	[4,4]	1	hSpCas9	positive selection	3816822
61852840	61852863	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGTTGATGAACTCAGGGCGG	CDH4	ENSG00000179242	-0.8409964189726458	[5]	[1,2]	-8	hSpCas9	positive selection	3816823
61910445	61910468	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGCGACCACGGTCTCCACGCGG	CDH4	ENSG00000179242	-0.042883073441916573	[5]	[3,4]	0	hSpCas9	positive selection	3816824
61910597	61910620	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.20468762978102323	[6]	[7,5]	5	hSpCas9	positive selection	3816825
61844753	61844776	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATTGACTCCATGTCCGGCCGG	CDH4	ENSG00000179242	0.2868777780439703	[6]	[7,6]	7	hSpCas9	positive selection	3816826
61773135	61773158	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACGTGCCCGAGAACTCGCGCGG	CDH4	ENSG00000179242	0.020236396402791262	[6]	[5,4]	0	hSpCas9	positive selection	3816827
61252557	61252580	20	-	26780180	A375	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.261479869417739	[]	[]	0	hSpCas9	negative selection	3924992
61252508	61252531	20	+	26780180	A375	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	1.15735991240573	[]	[]	6	hSpCas9	negative selection	3924993
61254816	61254839	20	+	26780180	A375	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	1.51712631011261	[]	[]	8	hSpCas9	negative selection	3924994
61254828	61254851	20	-	26780180	A375	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.734717596247826	[]	[]	2	hSpCas9	negative selection	3924995
61252557	61252580	20	-	26780180	HT29	viability (GeCKOv2 library)	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.344409068570409	[]	[]	0	hSpCas9	negative selection	4032958
61252508	61252531	20	+	26780180	HT29	viability (GeCKOv2 library)	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	1.09569226728984	[]	[]	5	hSpCas9	negative selection	4032959
61254816	61254839	20	+	26780180	HT29	viability (GeCKOv2 library)	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	1.15250863556059	[]	[]	5	hSpCas9	negative selection	4032960
61254828	61254851	20	-	26780180	HT29	viability (GeCKOv2 library)	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.669144475102766	[]	[]	2	hSpCas9	negative selection	4032961
61252557	61252580	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.3644930323683726	[2]	[1,0]	-7	hSpCas9	positive selection	4126533
61254843	61254866	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACAACTAGAGAGACCTGCAAGG	CDH4	ENSG00000179242	-0.5570316913316355	[3]	[1,0]	-9	hSpCas9	positive selection	4126534
61773097	61773120	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAGGCGGCGCAAACGGGACTGG	CDH4	ENSG00000179242	-0.0663207705788299	[3]	[1,1]	-1	hSpCas9	positive selection	4126535
61773088	61773111	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGCGCCGCCTCAGCCCGTTGG	CDH4	ENSG00000179242	-0.15848631313026784	[4]	[2,2]	-4	hSpCas9	positive selection	4126538
61252557	61252580	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.27718849875990437	[2]	[1,0,0,0]	-4	hSpCas9	positive selection	4190555
61254843	61254866	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACAACTAGAGAGACCTGCAAGG	CDH4	ENSG00000179242	0.17520423128379542	[2]	[0,2,0,0]	1	hSpCas9	positive selection	4190556
61773097	61773120	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAGGCGGCGCAAACGGGACTGG	CDH4	ENSG00000179242	1.2342012526226167	[2]	[3,0,0,3]	8	hSpCas9	positive selection	4190557
61773088	61773111	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGCGCCGCCTCAGCCCGTTGG	CDH4	ENSG00000179242	0.3361466666171259	[3]	[5,2,1,0]	2	hSpCas9	positive selection	4190560
61252557	61252580	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.30880120773980946	[0]	[0,0]	6	hSpCas9	positive selection	4262377
61252508	61252531	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.03277748117102586	[1]	[0,1]	0	hSpCas9	positive selection	4262379
61254828	61254851	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.13862002481851626	[2]	[2,1]	2	hSpCas9	positive selection	4326656
61254816	61254839	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.27828417087116714	[2]	[2,0]	-5	hSpCas9	positive selection	4326657
61773137	61773159	20	+	27760321	OCIAML3	viability	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	-0.0666671621234648	[897,816]	[540,768]	0	hSpCas9	negative selection	4387921
61844695	61844717	20	-	27760321	OCIAML3	viability	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	-0.4064188065027094	[777,647]	[365,487]	-4	hSpCas9	negative selection	4387922
61844769	61844791	20	+	27760321	OCIAML3	viability	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.3724806165493342	[787,696]	[647,883]	4	hSpCas9	negative selection	4387923
61873779	61873801	20	-	27760321	OCIAML3	viability	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	-0.014915701599166997	[951,837]	[489,953]	0	hSpCas9	negative selection	4387924
61910566	61910588	20	+	27760321	OCIAML3	viability	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.39668999855151277	[557,397]	[407,589]	5	hSpCas9	negative selection	4387925
61773137	61773159	20	+	27760321	OCIAML2	viability	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	-0.07036177085786532	[897,816]	[661,657]	-1	hSpCas9	negative selection	4471384
61844695	61844717	20	-	27760321	OCIAML2	viability	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	-0.3990355503903455	[777,647]	[350,546]	-5	hSpCas9	negative selection	4471385
61844769	61844791	20	+	27760321	OCIAML2	viability	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.06634922890615691	[787,696]	[673,566]	0	hSpCas9	negative selection	4471386
61873779	61873801	20	-	27760321	OCIAML2	viability	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	-0.03635856957368522	[951,837]	[695,715]	0	hSpCas9	negative selection	4471387
61910566	61910588	20	+	27760321	OCIAML2	viability	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.224575312904238	[557,397]	[308,628]	3	hSpCas9	negative selection	4471388
61773137	61773159	20	+	27760321	MV411	viability	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	-0.27354889709323504	[897,816]	[530,372]	-2	hSpCas9	negative selection	4554847
61844695	61844717	20	-	27760321	MV411	viability	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	-0.9778946359783116	[777,647]	[97,447]	-6	hSpCas9	negative selection	4554848
61844769	61844791	20	+	27760321	MV411	viability	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.8834403312875412	[787,696]	[1040,693]	6	hSpCas9	negative selection	4554849
61873779	61873801	20	-	27760321	MV411	viability	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.32893135194634593	[951,837]	[757,713]	2	hSpCas9	negative selection	4554850
61910566	61910588	20	+	27760321	MV411	viability	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.027661393039739468	[557,397]	[290,358]	0	hSpCas9	negative selection	4554851
61773137	61773159	20	+	27760321	HL60	viability	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	0.16315782513290178	[897,816]	[580,998]	2	hSpCas9	negative selection	4638310
61844695	61844717	20	-	27760321	HL60	viability	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.1486084539308199	[777,647]	[606,680]	1	hSpCas9	negative selection	4638311
61844769	61844791	20	+	27760321	HL60	viability	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.6552699164763662	[787,696]	[1021,880]	7	hSpCas9	negative selection	4638312
61873779	61873801	20	-	27760321	HL60	viability	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	-0.19063458925280663	[951,837]	[667,608]	-2	hSpCas9	negative selection	4638313
61910566	61910588	20	+	27760321	HL60	viability	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.258388105238811	[557,397]	[500,420]	3	hSpCas9	negative selection	4638314
61773137	61773159	20	+	27760321	HT1080	viability	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	1.0717071105905658	[816,637]	[296,950]	6	hSpCas9	negative selection	4721773
61844695	61844717	20	-	27760321	HT1080	viability	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.8914450676401743	[647,505]	[413,439]	5	hSpCas9	negative selection	4721774
61844769	61844791	20	+	27760321	HT1080	viability	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.8869071826774452	[696,543]	[648,246]	5	hSpCas9	negative selection	4721775
61873779	61873801	20	-	27760321	HT1080	viability	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.5612164183231918	[837,653]	[311,576]	3	hSpCas9	negative selection	4721776
61910566	61910588	20	+	27760321	HT1080	viability	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.2588872950998337	[397,310]	[210,122]	1	hSpCas9	negative selection	4721777
61773137	61773159	20	+	27760321	HT29	viability after 7 days	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	-0.07818183419435265	[816,637]	[1093,1039,562]	-1	hSpCas9	negative selection	4805236
61844695	61844717	20	-	27760321	HT29	viability after 7 days	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.2344919117200468	[647,505]	[1008,703,921]	3	hSpCas9	negative selection	4805237
61844769	61844791	20	+	27760321	HT29	viability after 7 days	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.19603447902906113	[696,543]	[973,989,788]	3	hSpCas9	negative selection	4805238
61873779	61873801	20	-	27760321	HT29	viability after 7 days	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	-0.286803696905508	[837,653]	[789,906,664]	-4	hSpCas9	negative selection	4805239
61910566	61910588	20	+	27760321	HT29	viability after 7 days	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.5336057639985462	[397,310]	[787,587,621]	7	hSpCas9	negative selection	4805240
61773137	61773159	20	+	27760321	HT29	viability after 25 days	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	0.38397700412252855	[816,637]	[956,1178,1129]	4	hSpCas9	negative selection	4888699
61844695	61844717	20	-	27760321	HT29	viability after 25 days	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.6235648262296315	[647,505]	[1041,1061,931]	7	hSpCas9	negative selection	4888700
61844769	61844791	20	+	27760321	HT29	viability after 25 days	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.6666702814407547	[696,543]	[983,948,1488]	7	hSpCas9	negative selection	4888701
61873779	61873801	20	-	27760321	HT29	viability after 25 days	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.12037110117017269	[837,653]	[893,975,908]	1	hSpCas9	negative selection	4888702
61910566	61910588	20	+	27760321	HT29	viability after 25 days	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.7768930990429639	[397,310]	[751,708,607]	8	hSpCas9	negative selection	4888703
61773137	61773159	20	+	27760321	HT29	viability after 22 days	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	0.4410303015877548	[816,637]	[1109,1194,1120]	5	hSpCas9	negative selection	4972162
61844695	61844717	20	-	27760321	HT29	viability after 22 days	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.6611702890858818	[647,505]	[1081,1217,861]	7	hSpCas9	negative selection	4972163
61844769	61844791	20	+	27760321	HT29	viability after 22 days	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.5929836536336172	[696,543]	[1064,931,1250]	6	hSpCas9	negative selection	4972164
61873779	61873801	20	-	27760321	HT29	viability after 22 days	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.009351024125084262	[837,653]	[768,937,899]	0	hSpCas9	negative selection	4972165
61910566	61910588	20	+	27760321	HT29	viability after 22 days	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.7281606773048449	[397,310]	[1085,443,493]	7	hSpCas9	negative selection	4972166
61773137	61773159	20	+	27760321	HT29	viability after 19 days	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	0.6829686786789517	[816,637]	[1475,1337,1211]	7	hSpCas9	negative selection	5055625
61844695	61844717	20	-	27760321	HT29	viability after 19 days	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.4419905390156006	[647,505]	[912,784,988]	4	hSpCas9	negative selection	5055626
61844769	61844791	20	+	27760321	HT29	viability after 19 days	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.9389126066698036	[696,543]	[1648,1136,1325]	8	hSpCas9	negative selection	5055627
61873779	61873801	20	-	27760321	HT29	viability after 19 days	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.17283042603061793	[837,653]	[1212,737,959]	1	hSpCas9	negative selection	5055628
61910566	61910588	20	+	27760321	HT29	viability after 19 days	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.7317123966230251	[397,310]	[1090,453,523]	7	hSpCas9	negative selection	5055629
61773137	61773159	20	+	27760321	HT29	viability after 16 days	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	0.6189404891052357	[816,637]	[1400,949,1420]	7	hSpCas9	negative selection	5139088
61844695	61844717	20	-	27760321	HT29	viability after 16 days	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.18377652064932626	[647,505]	[785,950,461]	2	hSpCas9	negative selection	5139089
61844769	61844791	20	+	27760321	HT29	viability after 16 days	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.8600525997581153	[696,543]	[1238,1261,1276]	8	hSpCas9	negative selection	5139090
61873779	61873801	20	-	27760321	HT29	viability after 16 days	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.16339965654391753	[837,653]	[1204,801,825]	1	hSpCas9	negative selection	5139091
61910566	61910588	20	+	27760321	HT29	viability after 16 days	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.898102120064943	[397,310]	[722,774,716]	9	hSpCas9	negative selection	5139092
61773137	61773159	20	+	27760321	HT29	viability after 13 days	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	0.4032517249284988	[816,637]	[1120,1343,896]	5	hSpCas9	negative selection	5222551
61844695	61844717	20	-	27760321	HT29	viability after 13 days	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.5580739403053726	[647,505]	[982,1268,720]	7	hSpCas9	negative selection	5222552
61844769	61844791	20	+	27760321	HT29	viability after 13 days	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.3743950969550748	[696,543]	[766,1105,926]	5	hSpCas9	negative selection	5222553
61873779	61873801	20	-	27760321	HT29	viability after 13 days	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.03008252651302712	[837,653]	[1039,871,746]	0	hSpCas9	negative selection	5222554
61910566	61910588	20	+	27760321	HT29	viability after 13 days	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.6436846929376611	[397,310]	[871,377,674]	8	hSpCas9	negative selection	5222555
61773137	61773159	20	+	27760321	HT29	viability after 10 days	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	0.20070838938445745	[816,637]	[1035,1234,869]	2	hSpCas9	negative selection	5306014
61844695	61844717	20	-	27760321	HT29	viability after 10 days	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.13842589996076438	[647,505]	[668,991,724]	1	hSpCas9	negative selection	5306015
61844769	61844791	20	+	27760321	HT29	viability after 10 days	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.4752831872475126	[696,543]	[1095,1190,949]	6	hSpCas9	negative selection	5306016
61873779	61873801	20	-	27760321	HT29	viability after 10 days	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	-0.22561753023161635	[837,653]	[795,864,731]	-3	hSpCas9	negative selection	5306017
61910566	61910588	20	+	27760321	HT29	viability after 10 days	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.8646188604287948	[397,310]	[996,502,906]	9	hSpCas9	negative selection	5306018
61773137	61773159	20	+	27760321	MOLM13	viability	CGTGCCCGAGAACTCGCGCGGG	CDH4	ENSG00000179242	1.1343668263366835	[897,816]	[685,1380]	7	hSpCas9	negative selection	5389477
61844695	61844717	20	-	27760321	MOLM13	viability	CCGTGATGCTGTACCGGATGGG	CDH4	ENSG00000179242	0.18734482052041646	[777,647]	[561,365]	1	hSpCas9	negative selection	5389478
61844769	61844791	20	+	27760321	MOLM13	viability	CGGCCGGATGTACGTCACAAGG	CDH4	ENSG00000179242	0.8684863974202066	[787,696]	[1045,522]	6	hSpCas9	negative selection	5389479
61873779	61873801	20	-	27760321	MOLM13	viability	CGGTACCGCACCATCCCGTTGG	CDH4	ENSG00000179242	0.33948910265942467	[951,837]	[1105,238]	2	hSpCas9	negative selection	5389480
61910566	61910588	20	+	27760321	MOLM13	viability	ACAGACCCCGTAACCAACGAGG	CDH4	ENSG00000179242	0.18061106920102	[557,397]	[181,404]	1	hSpCas9	negative selection	5389481
61252408	61252431	20	+	27661255	K562	viability	GGCGGCGGCGGCGATCGGAGCGG	CDH4	ENSG00000179242	0.49882646530337915	[171,210]	[223,207]	9	dCas9-KRAB	negative selection	5469819
61252557	61252580	20	-	27260156	BXPC3	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.051184969862115626	[30]	[24,23,31,46]	-1	hSpCas9	negative selection	5534837
61252508	61252531	20	+	27260156	BXPC3	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.18847660097869023	[159]	[158,86,132,217]	-4	hSpCas9	negative selection	5534839
61254828	61254851	20	-	27260156	BXPC3	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.019622945446118645	[241]	[246,253,250,243]	0	hSpCas9	negative selection	5599116
61254816	61254839	20	+	27260156	BXPC3	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.11844093314684362	[389]	[338,436,328,396]	-3	hSpCas9	negative selection	5599117
61252557	61252580	20	-	27260156	A673	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.2955215861153282	[30]	[61,53,44,21]	7	hSpCas9	negative selection	5656088
61252508	61252531	20	+	27260156	A673	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.29741293812234715	[159]	[248,208,236,251]	7	hSpCas9	negative selection	5656090
61254828	61254851	20	-	27260156	A673	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.1162721937821295	[241]	[328,284,353,291]	2	hSpCas9	negative selection	5720367
61254816	61254839	20	+	27260156	A673	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.0980297637400257	[389]	[470,372,420,492]	-2	hSpCas9	negative selection	5720368
61252557	61252580	20	-	27260156	A375	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.7486952207971513	[30]	[43,128,41,39]	9	hSpCas9	negative selection	5777339
61252508	61252531	20	+	27260156	A375	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.8297531192099028	[159]	[65,169,97,95]	-8	hSpCas9	negative selection	5777341
61254828	61254851	20	-	27260156	A375	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.14453405258304486	[241]	[251,309,467,227]	2	hSpCas9	negative selection	5841618
61254816	61254839	20	+	27260156	A375	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.7203289252090257	[389]	[230,253,437,188]	-7	hSpCas9	negative selection	5841619
61252557	61252580	20	-	27260156	COLO741	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.3584268642806205	[30]	[31,238,32]	9	hSpCas9	negative selection	5898590
61252508	61252531	20	+	27260156	COLO741	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.042877639431909254	[159]	[167,237,220]	0	hSpCas9	negative selection	5898592
61254828	61254851	20	-	27260156	COLO741	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.1364284235623855	[241]	[410,388,232]	3	hSpCas9	negative selection	5962869
61254816	61254839	20	+	27260156	COLO741	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	0.005746409357134774	[389]	[504,450,540]	0	hSpCas9	negative selection	5962870
61252557	61252580	20	-	27260156	CAL120	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.8152152413581923	[30]	[23,15,25]	-8	hSpCas9	negative selection	6019841
61252508	61252531	20	+	27260156	CAL120	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.1614869548332738	[159]	[294,281,103]	2	hSpCas9	negative selection	6019843
61254828	61254851	20	-	27260156	CAL120	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.3646212228773432	[241]	[395,252,512]	5	hSpCas9	negative selection	6084120
61254816	61254839	20	+	27260156	CAL120	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.11251031616827223	[389]	[432,566,345]	-2	hSpCas9	negative selection	6084121
61252557	61252580	20	-	27260156	CADOES1	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.21364383127630093	[30]	[37,28,25,40]	3	hSpCas9	negative selection	6141092
61252508	61252531	20	+	27260156	CADOES1	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.28806007600868244	[159]	[117,77,128,163]	-5	hSpCas9	negative selection	6141094
61254828	61254851	20	-	27260156	CADOES1	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.005395032579077141	[241]	[336,131,214,211]	0	hSpCas9	negative selection	6205371
61254816	61254839	20	+	27260156	CADOES1	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.001817536516455609	[389]	[308,432,353,352]	0	hSpCas9	negative selection	6205372
61252557	61252580	20	-	27260156	EWS502	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.6176285972349174	[30]	[31,44,78,47]	9	hSpCas9	negative selection	6262343
61252508	61252531	20	+	27260156	EWS502	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.15332861607290016	[159]	[206,144,110,137]	-3	hSpCas9	negative selection	6262345
61254828	61254851	20	-	27260156	EWS502	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.3517699417109922	[241]	[257,320,280,464]	6	hSpCas9	negative selection	6326622
61254816	61254839	20	+	27260156	EWS502	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	0.046251732124653916	[389]	[288,353,534,556]	0	hSpCas9	negative selection	6326623
61252557	61252580	20	-	27260156	EW8	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.5149077071037471	[30]	[61,24,19,41]	8	hSpCas9	negative selection	6383594
61252508	61252531	20	+	27260156	EW8	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.2919694260261074	[159]	[202,158,113,170]	5	hSpCas9	negative selection	6383596
61254828	61254851	20	-	27260156	EW8	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.3259287683102783	[241]	[314,324,185,174]	6	hSpCas9	negative selection	6447873
61254816	61254839	20	+	27260156	EW8	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.24272177179986648	[389]	[431,180,252,221]	-4	hSpCas9	negative selection	6447874
61252557	61252580	20	-	27260156	CORL105	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.6531688886736502	[30]	[72,14,59,81]	9	hSpCas9	negative selection	6504845
61252508	61252531	20	+	27260156	CORL105	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.29844341506474437	[159]	[240,194,215,267]	5	hSpCas9	negative selection	6504847
61254828	61254851	20	-	27260156	CORL105	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.041573429671801776	[241]	[353,132,267,349]	-1	hSpCas9	negative selection	6569124
61254816	61254839	20	+	27260156	CORL105	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.1113919573856994	[389]	[526,339,436,393]	-2	hSpCas9	negative selection	6569125
61252557	61252580	20	-	27260156	HS294T	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.0022228407486087	[30]	[8,11,16,66]	9	hSpCas9	negative selection	6626096
61252508	61252531	20	+	27260156	HS294T	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	1.212810390179533	[159]	[104,189,77,213]	9	hSpCas9	negative selection	6626098
61254828	61254851	20	-	27260156	HS294T	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.4641039807611188	[241]	[233,117,69,74]	6	hSpCas9	negative selection	6690375
61254816	61254839	20	+	27260156	HS294T	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.9487793908523607	[389]	[64,67,96,84]	-8	hSpCas9	negative selection	6690376
61252557	61252580	20	-	27260156	HCC44	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.02779628941678025	[30]	[39,39,36,25]	0	hSpCas9	negative selection	6747347
61252508	61252531	20	+	27260156	HCC44	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.28542558931204365	[159]	[164,70,163,205]	-4	hSpCas9	negative selection	6747349
61254828	61254851	20	-	27260156	HCC44	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.14304764881929433	[241]	[277,214,269,237]	-2	hSpCas9	negative selection	6811626
61254816	61254839	20	+	27260156	HCC44	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-1.2166493316048015	[389]	[241,139,283,121]	-9	hSpCas9	negative selection	6811627
61252557	61252580	20	-	27260156	G402	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.9086285711852717	[30]	[11,149,7,107]	9	hSpCas9	negative selection	6868598
61252508	61252531	20	+	27260156	G402	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.06231063512904966	[159]	[245,147,56,296]	-1	hSpCas9	negative selection	6868600
61254828	61254851	20	-	27260156	G402	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.318957840095223	[241]	[319,706,180,280]	4	hSpCas9	negative selection	6932877
61254816	61254839	20	+	27260156	G402	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.40725138291731716	[389]	[230,365,376,437]	-5	hSpCas9	negative selection	6932878
61252557	61252580	20	-	27260156	L33	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.14208036786522982	[30]	[27,3,36,15]	-3	hSpCas9	negative selection	6989849
61252508	61252531	20	+	27260156	L33	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.3953180801786542	[159]	[202,113,149,122]	7	hSpCas9	negative selection	6989851
61254828	61254851	20	-	27260156	L33	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.2835403686894481	[241]	[193,52,116,284]	-6	hSpCas9	negative selection	7054128
61254816	61254839	20	+	27260156	L33	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.04178880685957309	[389]	[343,190,251,305]	-1	hSpCas9	negative selection	7054129
61252557	61252580	20	-	27260156	K562	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.288003888607542	[30]	[9,17,30,28]	-4	hSpCas9	negative selection	7111100
61252508	61252531	20	+	27260156	K562	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.22661943278195107	[159]	[191,274,50,154]	3	hSpCas9	negative selection	7111102
61254828	61254851	20	-	27260156	K562	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.8289905646967899	[241]	[182,1154,189,58]	9	hSpCas9	negative selection	7175379
61254816	61254839	20	+	27260156	K562	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.3020812745306621	[389]	[172,252,485,207]	-4	hSpCas9	negative selection	7175380
61252557	61252580	20	-	27260156	HT29	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.4541733011599747	[30]	[101,51,39,19]	8	hSpCas9	negative selection	7232351
61252508	61252531	20	+	27260156	HT29	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.1769409410300029	[159]	[269,264,178,176]	3	hSpCas9	negative selection	7232353
61254828	61254851	20	-	27260156	HT29	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.3799309833865414	[241]	[342,498,441,265]	7	hSpCas9	negative selection	7296630
61254816	61254839	20	+	27260156	HT29	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	0.09027294001378064	[389]	[499,623,512,400]	1	hSpCas9	negative selection	7296631
61252557	61252580	20	-	27260156	MHHES1	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.4477408261054068	[30]	[49,116,35,3]	7	hSpCas9	negative selection	7353602
61252508	61252531	20	+	27260156	MHHES1	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.39056980187251944	[159]	[376,185,258,149]	7	hSpCas9	negative selection	7353604
61254828	61254851	20	-	27260156	MHHES1	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.16535420160998737	[241]	[242,360,270,331]	3	hSpCas9	negative selection	7417881
61254816	61254839	20	+	27260156	MHHES1	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	0.13046839486281325	[389]	[524,563,410,435]	2	hSpCas9	negative selection	7417882
61252557	61252580	20	-	27260156	MEWO	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.19495317925892053	[30]	[39,13,46]	4	hSpCas9	negative selection	7474853
61252508	61252531	20	+	27260156	MEWO	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.1699889591334085	[159]	[177,98,130]	-4	hSpCas9	negative selection	7474855
61254828	61254851	20	-	27260156	MEWO	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.2132944663881865	[241]	[184,160,237]	-5	hSpCas9	negative selection	7539132
61254816	61254839	20	+	27260156	MEWO	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.07831994180232105	[389]	[393,359,291]	-2	hSpCas9	negative selection	7539133
61252557	61252580	20	-	27260156	LNCAPCLONEFGC	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.6453975594504038	[30]	[26,9,75,69]	8	hSpCas9	negative selection	7596104
61252508	61252531	20	+	27260156	LNCAPCLONEFGC	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.0866649788042908	[159]	[177,163,130,137]	1	hSpCas9	negative selection	7596106
61254828	61254851	20	-	27260156	LNCAPCLONEFGC	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.1909430152427608	[241]	[212,172,299,327]	3	hSpCas9	negative selection	7660383
61254816	61254839	20	+	27260156	LNCAPCLONEFGC	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.261704558937983	[389]	[206,343,348,284]	-4	hSpCas9	negative selection	7660384
61252557	61252580	20	-	27260156	PANC0327	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.24566268489901422	[30]	[82,5,3,6]	-4	hSpCas9	negative selection	7717355
61252508	61252531	20	+	27260156	PANC0327	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.5524967284581075	[159]	[249,77,245,279]	7	hSpCas9	negative selection	7717357
61254828	61254851	20	-	27260156	PANC0327	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.4071312551135793	[241]	[372,266,394,114]	6	hSpCas9	negative selection	7781634
61254816	61254839	20	+	27260156	PANC0327	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.5976197046682354	[389]	[140,355,173,220]	-7	hSpCas9	negative selection	7781635
61252557	61252580	20	-	27260156	NCIH2009	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.029282688297247	[30]	[85,64,113]	9	hSpCas9	negative selection	7838606
61252508	61252531	20	+	27260156	NCIH2009	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.8992422764146677	[159]	[534,329,409]	9	hSpCas9	negative selection	7838608
61254828	61254851	20	-	27260156	NCIH2009	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.16845577318582017	[241]	[297,271,331]	-2	hSpCas9	negative selection	7902885
61254816	61254839	20	+	27260156	NCIH2009	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.5212275296158893	[389]	[488,322,348]	-6	hSpCas9	negative selection	7902886
61252557	61252580	20	-	27260156	NCIH1373	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.7053638165197853	[30]	[1,21,13,11]	-6	hSpCas9	negative selection	7959857
61252508	61252531	20	+	27260156	NCIH1373	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.750942638826536	[159]	[139,246,280,139]	7	hSpCas9	negative selection	7959859
61254828	61254851	20	-	27260156	NCIH1373	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.21651991133392146	[241]	[200,72,311,95]	-2	hSpCas9	negative selection	8024136
61254816	61254839	20	+	27260156	NCIH1373	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	0.1689686651357993	[389]	[670,513,438,93]	1	hSpCas9	negative selection	8024137
61252557	61252580	20	-	27260156	PATU8902	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.12203392606165675	[30]	[3,89,4,72]	-1	hSpCas9	negative selection	8081108
61252508	61252531	20	+	27260156	PATU8902	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.3626830922817712	[159]	[135,202,231,96]	-4	hSpCas9	negative selection	8081110
61254828	61254851	20	-	27260156	PATU8902	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.33463622336229026	[241]	[323,688,344,352]	3	hSpCas9	negative selection	8145387
61254816	61254839	20	+	27260156	PATU8902	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.4551701060746696	[389]	[494,296,229,628]	-4	hSpCas9	negative selection	8145388
61252557	61252580	20	-	27260156	PANC1	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.6683975969703555	[30]	[16,12,25,10]	-7	hSpCas9	negative selection	8202359
61252508	61252531	20	+	27260156	PANC1	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.4318472909911302	[159]	[217,231,225,87]	7	hSpCas9	negative selection	8202361
61254828	61254851	20	-	27260156	PANC1	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	-0.00805125766416026	[241]	[178,295,160,205]	0	hSpCas9	negative selection	8266638
61254816	61254839	20	+	27260156	PANC1	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.28943651439926993	[389]	[270,287,257,276]	-4	hSpCas9	negative selection	8266639
61252557	61252580	20	-	27260156	PANC0813	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.13458515244277125	[30]	[31,49,52,24]	2	hSpCas9	negative selection	8323610
61252508	61252531	20	+	27260156	PANC0813	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.37261446367262674	[159]	[293,306,200,178]	6	hSpCas9	negative selection	8323612
61254828	61254851	20	-	27260156	PANC0813	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.21519715856874033	[241]	[304,275,414,321]	3	hSpCas9	negative selection	8387889
61254816	61254839	20	+	27260156	PANC0813	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.12486880526033772	[389]	[474,471,396,344]	-2	hSpCas9	negative selection	8387890
61252557	61252580	20	-	27260156	RDES	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.16798413498783127	[30]	[16,34,34,43]	-3	hSpCas9	negative selection	8444861
61252508	61252531	20	+	27260156	RDES	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.32209629630397907	[159]	[122,122,111,247]	-5	hSpCas9	negative selection	8444863
61254828	61254851	20	-	27260156	RDES	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.2617985394029875	[241]	[254,240,424,451]	4	hSpCas9	negative selection	8509140
61254816	61254839	20	+	27260156	RDES	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.39573204646252264	[389]	[280,289,338,482]	-6	hSpCas9	negative selection	8509141
61252557	61252580	20	-	27260156	PC3	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.292930389848856	[30]	[36,205,33,8]	9	hSpCas9	negative selection	8566112
61252508	61252531	20	+	27260156	PC3	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.42112346985800087	[159]	[72,251,423,234]	8	hSpCas9	negative selection	8566114
61254828	61254851	20	-	27260156	PC3	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.15234202608460967	[241]	[159,211,510,311]	3	hSpCas9	negative selection	8630391
61254816	61254839	20	+	27260156	PC3	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.4789031366688244	[389]	[150,214,591,317]	-8	hSpCas9	negative selection	8630392
61252557	61252580	20	-	27260156	PATU8988T	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-1.1288930841787863	[30]	[3,26,11,12]	-9	hSpCas9	negative selection	8687363
61252508	61252531	20	+	27260156	PATU8988T	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.017629675621468888	[159]	[236,137,143,100]	0	hSpCas9	negative selection	8687365
61254828	61254851	20	-	27260156	PATU8988T	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.09844207017986617	[241]	[254,195,388,145]	1	hSpCas9	negative selection	8751642
61254816	61254839	20	+	27260156	PATU8988T	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.14440375139450978	[389]	[284,361,281,445]	-2	hSpCas9	negative selection	8751643
61252557	61252580	20	-	27260156	T47D	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.20794517607571494	[30]	[36,42,37,48]	4	hSpCas9	negative selection	8808614
61252508	61252531	20	+	27260156	T47D	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.17281615856482335	[159]	[202,161,240,238]	3	hSpCas9	negative selection	8808616
61254828	61254851	20	-	27260156	T47D	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.22033676036927874	[241]	[267,330,390,321]	5	hSpCas9	negative selection	8872893
61254816	61254839	20	+	27260156	T47D	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.014985302844845672	[389]	[393,366,473,573]	0	hSpCas9	negative selection	8872894
61252557	61252580	20	-	27260156	SU8686	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.3526770845743399	[30]	[36,11,75,35]	6	hSpCas9	negative selection	8929865
61252508	61252531	20	+	27260156	SU8686	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.49397820265434556	[159]	[219,173,266,241]	8	hSpCas9	negative selection	8929867
61254828	61254851	20	-	27260156	SU8686	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.024270565715437065	[241]	[259,198,201,329]	0	hSpCas9	negative selection	8994144
61254816	61254839	20	+	27260156	SU8686	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.0020917884590901936	[389]	[384,349,397,418]	0	hSpCas9	negative selection	8994145
61252557	61252580	20	-	27260156	SKES1	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.48113115147833607	[30]	[23,42,55,45]	8	hSpCas9	negative selection	9051116
61252508	61252531	20	+	27260156	SKES1	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.037449346026671826	[159]	[143,225,158,132]	0	hSpCas9	negative selection	9051118
61254828	61254851	20	-	27260156	SKES1	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.01631792126906495	[241]	[355,182,274,175]	0	hSpCas9	negative selection	9115395
61254816	61254839	20	+	27260156	SKES1	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	0.08286152680900688	[389]	[508,507,303,355]	1	hSpCas9	negative selection	9115396
61252557	61252580	20	-	27260156	TOV112D	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.2764038115740939	[30]	[22,110,24,8]	5	hSpCas9	negative selection	9172367
61252508	61252531	20	+	27260156	TOV112D	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.01914489787980167	[159]	[144,138,94,244]	0	hSpCas9	negative selection	9172369
61254828	61254851	20	-	27260156	TOV112D	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.3975608692050403	[241]	[433,443,230,210]	7	hSpCas9	negative selection	9236646
61254816	61254839	20	+	27260156	TOV112D	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	0.1175227732369292	[389]	[479,607,181,472]	2	hSpCas9	negative selection	9236647
61252557	61252580	20	-	27260156	TC71	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.47406031225446554	[30]	[26,26,61,69]	9	hSpCas9	negative selection	9293618
61252508	61252531	20	+	27260156	TC71	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	0.13190996270604605	[159]	[233,135,167,214]	3	hSpCas9	negative selection	9293620
61254828	61254851	20	-	27260156	TC71	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.05342543405830713	[241]	[159,313,274,333]	1	hSpCas9	negative selection	9357897
61254816	61254839	20	+	27260156	TC71	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.03798843940256752	[389]	[501,371,372,378]	-1	hSpCas9	negative selection	9357898
61252557	61252580	20	-	27260156	TC32	viability	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.6618952921302239	[30]	[30,64,29,46]	9	hSpCas9	negative selection	9414869
61252508	61252531	20	+	27260156	TC32	viability	GGGAAGATGACCGCGGGCGCCGG	CDH4	ENSG00000179242	-0.10459209551753168	[159]	[143,36,253,177]	-2	hSpCas9	negative selection	9414871
61254828	61254851	20	-	27260156	TC32	viability	TAGTTGTAAGATCCTCATTATGG	CDH4	ENSG00000179242	0.20693328142716538	[241]	[259,243,191,335]	4	hSpCas9	negative selection	9479148
61254816	61254839	20	+	27260156	TC32	viability	GTGTTCTCAGGCCCATAATGAGG	CDH4	ENSG00000179242	-0.2571179111327508	[389]	[312,211,436,303]	-5	hSpCas9	negative selection	9479149
61252557	61252580	20	-	27869803	HPAFII	viability after 27 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.840643856959822	[204]	[33,81,NaN]	-5	hSpCas9	negative selection	9578460
61773049	61773072	20	+	27869803	HPAFII	viability after 27 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.6249903603268075	[479]	[242,510,NaN]	5	hSpCas9	negative selection	9578472
61844768	61844791	20	-	27869803	HPAFII	viability after 27 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.3560978676934645	[183]	[101,141,NaN]	3	hSpCas9	negative selection	9578473
61852762	61852785	20	-	27869803	HPAFII	viability after 27 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	1.0396484868540827	[636]	[748,637,NaN]	8	hSpCas9	negative selection	9578474
61873768	61873791	20	+	27869803	HPAFII	viability after 27 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.5927801629039253	[398]	[185,99,NaN]	-4	hSpCas9	negative selection	9578475
61252557	61252580	20	-	27869803	HPAFII	viability after 15 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.3734638232392621	[204]	[211,143,NaN]	-4	hSpCas9	negative selection	9660909
61773049	61773072	20	+	27869803	HPAFII	viability after 15 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.5311346987590099	[479]	[742,746,NaN]	6	hSpCas9	negative selection	9660921
61844768	61844791	20	-	27869803	HPAFII	viability after 15 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.6832611770153225	[183]	[393,269,NaN]	7	hSpCas9	negative selection	9660922
61852762	61852785	20	-	27869803	HPAFII	viability after 15 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.9783599351389818	[636]	[1399,1316,NaN]	9	hSpCas9	negative selection	9660923
61873768	61873791	20	+	27869803	HPAFII	viability after 15 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.6127894162342675	[398]	[457,169,NaN]	-6	hSpCas9	negative selection	9660924
61252557	61252580	20	-	27869803	ASPC1	viability after 36 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	1.2437517080469669	[706]	[1145,405,325]	9	hSpCas9	negative selection	9743358
61773049	61773072	20	+	27869803	ASPC1	viability after 36 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.6163502364172457	[1137]	[459,923,456]	6	hSpCas9	negative selection	9743370
61844768	61844791	20	-	27869803	ASPC1	viability after 36 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.3562698754868837	[389]	[184,119,207]	3	hSpCas9	negative selection	9743371
61852762	61852785	20	-	27869803	ASPC1	viability after 36 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.6509260668303614	[1681]	[1170,463,1100]	6	hSpCas9	negative selection	9743372
61873768	61873791	20	+	27869803	ASPC1	viability after 36 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	0.5539519811400461	[814]	[357,112,696]	5	hSpCas9	negative selection	9743373
61252557	61252580	20	-	27869803	PATU8988S	viability after 35 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.4804219185380568	[626]	[487,215,NaN]	5	hSpCas9	negative selection	9825807
61773049	61773072	20	+	27869803	PATU8988S	viability after 35 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.11582742836619686	[1178]	[311,717,NaN]	1	hSpCas9	negative selection	9825819
61844768	61844791	20	-	27869803	PATU8988S	viability after 35 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.2003395319495188	[307]	[153,130,NaN]	2	hSpCas9	negative selection	9825820
61852762	61852785	20	-	27869803	PATU8988S	viability after 35 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.27841818220630343	[1869]	[895,930,NaN]	3	hSpCas9	negative selection	9825821
61873768	61873791	20	+	27869803	PATU8988S	viability after 35 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	0.05339193856909032	[542]	[199,253,NaN]	0	hSpCas9	negative selection	9825822
61252557	61252580	20	-	27869803	PATU8988S	viability after 31 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	0.022585512343847508	[626]	[238,272,NaN]	0	hSpCas9	negative selection	9908256
61773049	61773072	20	+	27869803	PATU8988S	viability after 31 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	-0.010919646431780228	[1178]	[338,628,NaN]	0	hSpCas9	negative selection	9908268
61844768	61844791	20	-	27869803	PATU8988S	viability after 31 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	-0.12129887567271203	[307]	[60,178,NaN]	-1	hSpCas9	negative selection	9908269
61852762	61852785	20	-	27869803	PATU8988S	viability after 31 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.45178637805829447	[1869]	[875,1202,NaN]	5	hSpCas9	negative selection	9908270
61873768	61873791	20	+	27869803	PATU8988S	viability after 31 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	0.347264481373098	[542]	[285,261,NaN]	4	hSpCas9	negative selection	9908271
61252557	61252580	20	-	27869803	HPAFII	viability after 35 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.07126411049007092	[204]	[7,200,NaN]	0	hSpCas9	negative selection	9990705
61773049	61773072	20	+	27869803	HPAFII	viability after 35 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.618122759026518	[479]	[197,569,NaN]	4	hSpCas9	negative selection	9990717
61844768	61844791	20	-	27869803	HPAFII	viability after 35 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.2424759630011377	[183]	[152,61,NaN]	1	hSpCas9	negative selection	9990718
61852762	61852785	20	-	27869803	HPAFII	viability after 35 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.9715225365950662	[636]	[510,768,NaN]	6	hSpCas9	negative selection	9990719
61873768	61873791	20	+	27869803	HPAFII	viability after 35 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-1.519211791588182	[398]	[69,70,NaN]	-7	hSpCas9	negative selection	9990720
61252557	61252580	20	-	27869803	HPAFII	viability after 31 days	GCAACTTACCCGGAGCGCGCCGG	CDH4	ENSG00000179242	-0.29811272546297984	[204]	[16,176,NaN]	-2	hSpCas9	negative selection	10073154
61773049	61773072	20	+	27869803	HPAFII	viability after 31 days	CGAAGGACACCCTGCTGCCGTGG	CDH4	ENSG00000179242	0.3758061478595255	[479]	[182,530,NaN]	2	hSpCas9	negative selection	10073166
61844768	61844791	20	-	27869803	HPAFII	viability after 31 days	CCTTGTGACGTACATCCGGCCGG	CDH4	ENSG00000179242	0.7218043777956512	[183]	[165,174,NaN]	5	hSpCas9	negative selection	10073167
61852762	61852785	20	-	27869803	HPAFII	viability after 31 days	TGCCATTCATGTCCACAGCGTGG	CDH4	ENSG00000179242	0.7816082207330524	[636]	[369,880,NaN]	6	hSpCas9	negative selection	10073168
61873768	61873791	20	+	27869803	HPAFII	viability after 31 days	CAGCACCACGGCCAACGGGATGG	CDH4	ENSG00000179242	-0.6967073939727737	[398]	[163,109,NaN]	-4	hSpCas9	negative selection	10073169
61928302	61928325	20	+	28162770	P31FUJ	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.9020403378724882	[147]	[324]	9	hSpCas9	negative selection	10130419
61923518	61923541	20	-	28162770	P31FUJ	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.3879764756507492	[304]	[468]	4	hSpCas9	negative selection	10130420
61933043	61933066	20	+	28162770	P31FUJ	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.7791308250816014	[300]	[606]	8	hSpCas9	negative selection	10130421
61772999	61773022	20	+	28162770	P31FUJ	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.4400330523321119	[68]	[109]	5	hSpCas9	negative selection	10130422
61844784	61844807	20	+	28162770	P31FUJ	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	1.0384998174030158	[86]	[209]	9	hSpCas9	negative selection	10130423
61852750	61852773	20	+	28162770	P31FUJ	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.7626250657957974	[315]	[629]	8	hSpCas9	negative selection	10130424
61895037	61895060	20	-	28162770	P31FUJ	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.25133323519457607	[478]	[669]	2	hSpCas9	negative selection	10130425
61910430	61910453	20	+	28162770	P31FUJ	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.13592010195192472	[181]	[234]	1	hSpCas9	negative selection	10130426
61910566	61910589	20	+	28162770	P31FUJ	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	-0.24371110358131753	[530]	[526]	-2	hSpCas9	negative selection	10130427
61910597	61910620	20	-	28162770	P31FUJ	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.07560756629828935	[578]	[716]	0	hSpCas9	negative selection	10130428
61928302	61928325	20	+	28162770	TF1	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10299785
61923518	61923541	20	-	28162770	TF1	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10299786
61933043	61933066	20	+	28162770	TF1	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10299787
61772999	61773022	20	+	28162770	TF1	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10299788
61844784	61844807	20	+	28162770	TF1	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10299789
61852750	61852773	20	+	28162770	TF1	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	NaN	[NaN]	[279]	1	hSpCas9	negative selection	10299790
61895037	61895060	20	-	28162770	TF1	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	NaN	[NaN]	[443]	1	hSpCas9	negative selection	10299791
61910430	61910453	20	+	28162770	TF1	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10299792
61910566	61910589	20	+	28162770	TF1	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	NaN	[NaN]	[670]	1	hSpCas9	negative selection	10299793
61910597	61910620	20	-	28162770	TF1	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	NaN	[NaN]	[458]	1	hSpCas9	negative selection	10299794
61928302	61928325	20	+	28162770	SKM1	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.9915851777471132	[32]	[115]	8	hSpCas9	negative selection	10469151
61923518	61923541	20	-	28162770	SKM1	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	-0.7548875021634687	[62]	[65]	-5	hSpCas9	negative selection	10469152
61933043	61933066	20	+	28162770	SKM1	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	1.2577254944487286	[87]	[371]	9	hSpCas9	negative selection	10469153
61772999	61773022	20	+	28162770	SKM1	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.6667454874398475	[30]	[86]	6	hSpCas9	negative selection	10469154
61844784	61844807	20	+	28162770	SKM1	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	-0.4069641987431618	[26]	[35]	-3	hSpCas9	negative selection	10469155
61852750	61852773	20	+	28162770	SKM1	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.18498473229410128	[102]	[206]	1	hSpCas9	negative selection	10469156
61895037	61895060	20	-	28162770	SKM1	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.6024961305059044	[113]	[305]	6	hSpCas9	negative selection	10469157
61910430	61910453	20	+	28162770	SKM1	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	-0.5064998722940761	[44]	[55]	-4	hSpCas9	negative selection	10469158
61910566	61910589	20	+	28162770	SKM1	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.5911362683413568	[94]	[252]	6	hSpCas9	negative selection	10469159
61910597	61910620	20	-	28162770	SKM1	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.470280935116832	[117]	[288]	4	hSpCas9	negative selection	10469160
61928302	61928325	20	+	28162770	SKM1	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.9915851777471132	[32]	[115]	8	hSpCas9	negative selection	10638517
61923518	61923541	20	-	28162770	SKM1	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	-0.7548875021634687	[62]	[65]	-5	hSpCas9	negative selection	10638518
61933043	61933066	20	+	28162770	SKM1	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	1.2577254944487286	[87]	[371]	9	hSpCas9	negative selection	10638519
61772999	61773022	20	+	28162770	SKM1	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.6667454874398475	[30]	[86]	6	hSpCas9	negative selection	10638520
61844784	61844807	20	+	28162770	SKM1	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	-0.4069641987431618	[26]	[35]	-3	hSpCas9	negative selection	10638521
61852750	61852773	20	+	28162770	SKM1	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.18498473229410128	[102]	[206]	1	hSpCas9	negative selection	10638522
61895037	61895060	20	-	28162770	SKM1	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.6024961305059044	[113]	[305]	6	hSpCas9	negative selection	10638523
61910430	61910453	20	+	28162770	SKM1	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	-0.5064998722940761	[44]	[55]	-4	hSpCas9	negative selection	10638524
61910566	61910589	20	+	28162770	SKM1	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.5911362683413568	[94]	[252]	6	hSpCas9	negative selection	10638525
61910597	61910620	20	-	28162770	SKM1	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.470280935116832	[117]	[288]	4	hSpCas9	negative selection	10638526
61928302	61928325	20	+	28162770	PL21	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.5120836208040603	[144]	[89]	4	hSpCas9	negative selection	10807883
61923518	61923541	20	-	28162770	PL21	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	-0.3614588931663257	[244]	[82]	-3	hSpCas9	negative selection	10807884
61933043	61933066	20	+	28162770	PL21	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	-0.7047031524703398	[351]	[93]	-5	hSpCas9	negative selection	10807885
61772999	61773022	20	+	28162770	PL21	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	1.1552853787050597	[97]	[94]	8	hSpCas9	negative selection	10807886
61844784	61844807	20	+	28162770	PL21	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.05238599404562794	[112]	[50]	0	hSpCas9	negative selection	10807887
61852750	61852773	20	+	28162770	PL21	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	-0.13170394926312506	[291]	[115]	-1	hSpCas9	negative selection	10807888
61895037	61895060	20	-	28162770	PL21	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.31356567582367456	[378]	[204]	2	hSpCas9	negative selection	10807889
61910430	61910453	20	+	28162770	PL21	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.2192484374370248	[149]	[75]	2	hSpCas9	negative selection	10807890
61910566	61910589	20	+	28162770	PL21	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	-0.5644823225797514	[315]	[92]	-4	hSpCas9	negative selection	10807891
61910597	61910620	20	-	28162770	PL21	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.3767446811674484	[406]	[229]	3	hSpCas9	negative selection	10807892
61928302	61928325	20	+	28162770	P31FUJ	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.9020403378724882	[147]	[324]	9	hSpCas9	negative selection	10977249
61923518	61923541	20	-	28162770	P31FUJ	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.3879764756507492	[304]	[468]	4	hSpCas9	negative selection	10977250
61933043	61933066	20	+	28162770	P31FUJ	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.7791308250816014	[300]	[606]	8	hSpCas9	negative selection	10977251
61772999	61773022	20	+	28162770	P31FUJ	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.4400330523321119	[68]	[109]	5	hSpCas9	negative selection	10977252
61844784	61844807	20	+	28162770	P31FUJ	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	1.0384998174030158	[86]	[209]	9	hSpCas9	negative selection	10977253
61852750	61852773	20	+	28162770	P31FUJ	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.7626250657957974	[315]	[629]	8	hSpCas9	negative selection	10977254
61895037	61895060	20	-	28162770	P31FUJ	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.25133323519457607	[478]	[669]	2	hSpCas9	negative selection	10977255
61910430	61910453	20	+	28162770	P31FUJ	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.13592010195192472	[181]	[234]	1	hSpCas9	negative selection	10977256
61910566	61910589	20	+	28162770	P31FUJ	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	-0.24371110358131753	[530]	[526]	-2	hSpCas9	negative selection	10977257
61910597	61910620	20	-	28162770	P31FUJ	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.07560756629828935	[578]	[716]	0	hSpCas9	negative selection	10977258
61928302	61928325	20	+	28162770	OCIAML5	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	-0.7227835539190306	[95]	[104]	-5	hSpCas9	negative selection	11146615
61923518	61923541	20	-	28162770	OCIAML5	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.8781954830061326	[150]	[500]	7	hSpCas9	negative selection	11146616
61933043	61933066	20	+	28162770	OCIAML5	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.3228591116366819	[127]	[288]	2	hSpCas9	negative selection	11146617
61772999	61773022	20	+	28162770	OCIAML5	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.5105035085207112	[48]	[125]	4	hSpCas9	negative selection	11146618
61844784	61844807	20	+	28162770	OCIAML5	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.1364377902981736	[62]	[124]	1	hSpCas9	negative selection	11146619
61852750	61852773	20	+	28162770	OCIAML5	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.6295181900118505	[187]	[524]	5	hSpCas9	negative selection	11146620
61895037	61895060	20	-	28162770	OCIAML5	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.8651164111116716	[256]	[844]	7	hSpCas9	negative selection	11146621
61910430	61910453	20	+	28162770	OCIAML5	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.6564828143379913	[83]	[238]	6	hSpCas9	negative selection	11146622
61910566	61910589	20	+	28162770	OCIAML5	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	-0.22210057589005217	[262]	[406]	-2	hSpCas9	negative selection	11146623
61910597	61910620	20	-	28162770	OCIAML5	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.8242702828778932	[259]	[830]	7	hSpCas9	negative selection	11146624
61928302	61928325	20	+	28162770	EOL1	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.17015973108451032	[360]	[213]	1	hSpCas9	negative selection	11315981
61923518	61923541	20	-	28162770	EOL1	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.960171681301256	[279]	[286]	8	hSpCas9	negative selection	11315982
61933043	61933066	20	+	28162770	EOL1	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	-0.1704151721905558	[674]	[315]	-1	hSpCas9	negative selection	11315983
61772999	61773022	20	+	28162770	EOL1	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.27818472618523493	[179]	[114]	2	hSpCas9	negative selection	11315984
61844784	61844807	20	+	28162770	EOL1	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.8320356327809965	[160]	[150]	7	hSpCas9	negative selection	11315985
61852750	61852773	20	+	28162770	EOL1	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.6969187018679395	[643]	[549]	6	hSpCas9	negative selection	11315986
61895037	61895060	20	-	28162770	EOL1	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	-0.32920882067524837	[619]	[259]	-2	hSpCas9	negative selection	11315987
61910430	61910453	20	+	28162770	EOL1	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.3196857134116734	[145]	[95]	3	hSpCas9	negative selection	11315988
61910566	61910589	20	+	28162770	EOL1	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.5529325525828195	[479]	[370]	5	hSpCas9	negative selection	11315989
61910597	61910620	20	-	28162770	EOL1	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	-0.04707042705964304	[603]	[307]	0	hSpCas9	negative selection	11315990
61928302	61928325	20	+	28162770	MOLM13	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	0.4799622138451537	[237]	[239]	3	hSpCas9	negative selection	11485347
61923518	61923541	20	-	28162770	MOLM13	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.11879108549174627	[334]	[262]	0	hSpCas9	negative selection	11485348
61933043	61933066	20	+	28162770	MOLM13	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.5880613477897916	[471]	[512]	4	hSpCas9	negative selection	11485349
61772999	61773022	20	+	28162770	MOLM13	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	1.200193598340922	[123]	[205]	8	hSpCas9	negative selection	11485350
61844784	61844807	20	+	28162770	MOLM13	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.30255164959791836	[156]	[139]	2	hSpCas9	negative selection	11485351
61852750	61852773	20	+	28162770	MOLM13	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.5668558323455999	[506]	[542]	4	hSpCas9	negative selection	11485352
61895037	61895060	20	-	28162770	MOLM13	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.539680064612589	[587]	[617]	4	hSpCas9	negative selection	11485353
61910430	61910453	20	+	28162770	MOLM13	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.6214346397980341	[186]	[207]	5	hSpCas9	negative selection	11485354
61910566	61910589	20	+	28162770	MOLM13	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	-0.238504513603072	[606]	[371]	-1	hSpCas9	negative selection	11485355
61910597	61910620	20	-	28162770	MOLM13	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.09054640561347105	[616]	[474]	0	hSpCas9	negative selection	11485356
61928302	61928325	20	+	28162770	HEL	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	-1.281973040695406	[223]	[58]	-6	hSpCas9	negative selection	11654713
61923518	61923541	20	-	28162770	HEL	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.4445127217946614	[295]	[257]	4	hSpCas9	negative selection	11654714
61933043	61933066	20	+	28162770	HEL	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	-0.13012771367195652	[433]	[253]	-1	hSpCas9	negative selection	11654715
61772999	61773022	20	+	28162770	HEL	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.7505421215348718	[115]	[124]	6	hSpCas9	negative selection	11654716
61844784	61844807	20	+	28162770	HEL	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.6208793980366178	[132]	[130]	5	hSpCas9	negative selection	11654717
61852750	61852773	20	+	28162770	HEL	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	-0.29299477219901926	[460]	[240]	-2	hSpCas9	negative selection	11654718
61895037	61895060	20	-	28162770	HEL	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	-0.772298667278487	[487]	[182]	-5	hSpCas9	negative selection	11654719
61910430	61910453	20	+	28162770	HEL	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.016356403899219996	[158]	[102]	0	hSpCas9	negative selection	11654720
61910566	61910589	20	+	28162770	HEL	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.667140175490492	[468]	[476]	6	hSpCas9	negative selection	11654721
61910597	61910620	20	-	28162770	HEL	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	-1.1421612392295513	[509]	[147]	-6	hSpCas9	negative selection	11654722
61928302	61928325	20	+	28162770	MV411	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	-0.46384139971978133	[166]	[101]	-3	hSpCas9	negative selection	11824079
61923518	61923541	20	-	28162770	MV411	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.9329269274578958	[193]	[311]	8	hSpCas9	negative selection	11824080
61933043	61933066	20	+	28162770	MV411	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.6063804879906928	[353]	[453]	5	hSpCas9	negative selection	11824081
61772999	61773022	20	+	28162770	MV411	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	1.1657537531890676	[108]	[205]	9	hSpCas9	negative selection	11824082
61844784	61844807	20	+	28162770	MV411	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.23575574573514008	[123]	[122]	2	hSpCas9	negative selection	11824083
61852750	61852773	20	+	28162770	MV411	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	-0.24441554554689937	[359]	[255]	-2	hSpCas9	negative selection	11824084
61895037	61895060	20	-	28162770	MV411	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.5755574793844056	[371]	[466]	5	hSpCas9	negative selection	11824085
61910430	61910453	20	+	28162770	MV411	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	0.9594567878187505	[104]	[171]	8	hSpCas9	negative selection	11824086
61910566	61910589	20	+	28162770	MV411	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.8171083995513411	[410]	[609]	7	hSpCas9	negative selection	11824087
61910597	61910620	20	-	28162770	MV411	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.26891727819322675	[399]	[405]	2	hSpCas9	negative selection	11824088
61928302	61928325	20	+	28162770	MONOMAC1	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	-0.3934340598630571	[109]	[95]	-3	hSpCas9	negative selection	11993445
61923518	61923541	20	-	28162770	MONOMAC1	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.8093894220998793	[111]	[224]	7	hSpCas9	negative selection	11993446
61933043	61933066	20	+	28162770	MONOMAC1	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.7561689414615053	[187]	[363]	7	hSpCas9	negative selection	11993447
61772999	61773022	20	+	28162770	MONOMAC1	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	0.9203201035786049	[58]	[127]	8	hSpCas9	negative selection	11993448
61844784	61844807	20	+	28162770	MONOMAC1	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	-0.1970368470595536	[61]	[61]	-2	hSpCas9	negative selection	11993449
61852750	61852773	20	+	28162770	MONOMAC1	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.08186396423326125	[210]	[255]	0	hSpCas9	negative selection	11993450
61895037	61895060	20	-	28162770	MONOMAC1	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.3827079443905834	[276]	[413]	4	hSpCas9	negative selection	11993451
61910430	61910453	20	+	28162770	MONOMAC1	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	-0.5893542698383142	[83]	[63]	-5	hSpCas9	negative selection	11993452
61910566	61910589	20	+	28162770	MONOMAC1	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.3356311462193896	[205]	[297]	3	hSpCas9	negative selection	11993453
61910597	61910620	20	-	28162770	MONOMAC1	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	0.4156911820443139	[222]	[340]	4	hSpCas9	negative selection	11993454
61928302	61928325	20	+	28162770	OCIAML2	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	-0.38970982985859387	[25]	[109]	-3	hSpCas9	negative selection	12162811
61923518	61923541	20	-	28162770	OCIAML2	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	0.6384918971379513	[34]	[301]	6	hSpCas9	negative selection	12162812
61933043	61933066	20	+	28162770	OCIAML2	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	0.12194585958887005	[62]	[379]	1	hSpCas9	negative selection	12162813
61772999	61773022	20	+	28162770	OCIAML2	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	1.1033615576579918	[10]	[130]	9	hSpCas9	negative selection	12162814
61844784	61844807	20	+	28162770	OCIAML2	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	0.17322636453256368	[19]	[124]	1	hSpCas9	negative selection	12162815
61852750	61852773	20	+	28162770	OCIAML2	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.16752561464458848	[70]	[441]	1	hSpCas9	negative selection	12162816
61895037	61895060	20	-	28162770	OCIAML2	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.6687284599043015	[52]	[466]	6	hSpCas9	negative selection	12162817
61910430	61910453	20	+	28162770	OCIAML2	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	1.488728190260493	[17]	[279]	9	hSpCas9	negative selection	12162818
61910566	61910589	20	+	28162770	OCIAML2	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.3702127521247629	[72]	[522]	3	hSpCas9	negative selection	12162819
61910597	61910620	20	-	28162770	OCIAML2	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	-0.027281929939940275	[81]	[445]	0	hSpCas9	negative selection	12162820
61928302	61928325	20	+	28162770	OCIAML3	viability	GAACGCCATCAACATCACGGCGG	CDH4	ENSG00000179242	-0.6200028488571077	[55]	[109]	-5	hSpCas9	negative selection	12332177
61923518	61923541	20	-	28162770	OCIAML3	viability	GAAGGACATCTGGATTCCGCTGG	CDH4	ENSG00000179242	-0.029223021540637384	[47]	[141]	0	hSpCas9	negative selection	12332178
61933043	61933066	20	+	28162770	OCIAML3	viability	GCAGCTGCTCATTGACCCCGAGG	CDH4	ENSG00000179242	-0.33481530078476346	[93]	[224]	-3	hSpCas9	negative selection	12332179
61772999	61773022	20	+	28162770	OCIAML3	viability	AAAGCCGCAGAAAGGAAAGAAGG	CDH4	ENSG00000179242	-0.11756959638117603	[22]	[63]	-1	hSpCas9	negative selection	12332180
61844784	61844807	20	+	28162770	OCIAML3	viability	CACAAGGCCCATGGACCGGGAGG	CDH4	ENSG00000179242	-1.2552057268724046	[33]	[42]	-7	hSpCas9	negative selection	12332181
61852750	61852773	20	+	28162770	OCIAML3	viability	CCAGCTCCGAGCCCACGCTGTGG	CDH4	ENSG00000179242	0.31476759962929823	[101]	[382]	3	hSpCas9	negative selection	12332182
61895037	61895060	20	-	28162770	OCIAML3	viability	CGAGGGACTCACCGTGCTGGCGG	CDH4	ENSG00000179242	0.47345532745457564	[93]	[393]	4	hSpCas9	negative selection	12332183
61910430	61910453	20	+	28162770	OCIAML3	viability	GGAGGTCCCCGAAAACCGCGTGG	CDH4	ENSG00000179242	1.299077155759325	[34]	[259]	9	hSpCas9	negative selection	12332184
61910566	61910589	20	+	28162770	OCIAML3	viability	ACAGACCCCGTAACCAACGAGGG	CDH4	ENSG00000179242	0.12804974654586987	[106]	[352]	1	hSpCas9	negative selection	12332185
61910597	61910620	20	-	28162770	OCIAML3	viability	AAGAGTACGCACCTTCACCACGG	CDH4	ENSG00000179242	-0.18237674248856883	[105]	[281]	-1	hSpCas9	negative selection	12332186