Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1003
• Symbol:CDH5
• Description:cadherin 5

DataSource: http://genomecrispr.dkfz.de/#!/results/CDH5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
66389401	66389424	16	+	26472758	Jiyoye	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.2986415140896683	[167]	[102]	-2	hSpCas9	negative selection	28506
66388426	66388449	16	-	26472758	Jiyoye	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.5536540212134488	[108]	[55]	-4	hSpCas9	negative selection	28507
66389466	66389489	16	-	26472758	Jiyoye	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	2.8334401362079715	[15]	[85]	9	hSpCas9	negative selection	28508
66390445	66390468	16	-	26472758	Jiyoye	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	-1.0574928854975711	[206]	[74]	-6	hSpCas9	negative selection	28509
66390548	66390571	16	+	26472758	Jiyoye	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	1.1420785092151873	[139]	[232]	7	hSpCas9	negative selection	28510
66392361	66392384	16	+	26472758	Jiyoye	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-0.13124453327825258	[60]	[41]	-1	hSpCas9	negative selection	28511
66379385	66379408	16	+	26472758	Jiyoye	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.14808816018874238	[72]	[60]	1	hSpCas9	negative selection	28512
66379442	66379465	16	-	26472758	Jiyoye	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-2.355785421193277	[223]	[32]	-8	hSpCas9	negative selection	28514
66388331	66388354	16	+	26472758	Jiyoye	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.8178077016647161	[81]	[108]	6	hSpCas9	negative selection	28515
66388384	66388407	16	-	26472758	Jiyoye	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.46527456877361556	[118]	[64]	-3	hSpCas9	negative selection	28516
66389401	66389424	16	+	26472758	KBM7	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.7371923614510836	[982,473]	[186,209]	-6	hSpCas9	negative selection	219624
66388426	66388449	16	-	26472758	KBM7	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.20419030378509678	[315,358]	[167,199]	2	hSpCas9	negative selection	219625
66389466	66389489	16	-	26472758	KBM7	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	-0.3370315240108339	[302,138]	[40,113]	-3	hSpCas9	negative selection	219626
66390445	66390468	16	-	26472758	KBM7	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.4880420376914687	[441,381]	[289,253]	5	hSpCas9	negative selection	219627
66390548	66390571	16	+	26472758	KBM7	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.756569527256719	[548,348]	[344,354]	8	hSpCas9	negative selection	219628
66392361	66392384	16	+	26472758	KBM7	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.5552038553381359	[340,339]	[257,216]	6	hSpCas9	negative selection	219629
66379385	66379408	16	+	26472758	KBM7	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.7586074047218354	[214,196]	[268,69]	8	hSpCas9	negative selection	219630
66379442	66379465	16	-	26472758	KBM7	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-0.45719934021054703	[986,685]	[289,275]	-4	hSpCas9	negative selection	219632
66388331	66388354	16	+	26472758	KBM7	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	1.028807474665379	[468,508]	[475,470]	9	hSpCas9	negative selection	219633
66388384	66388407	16	-	26472758	KBM7	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.34051054115908996	[365,329]	[176,233]	3	hSpCas9	negative selection	219634
66389401	66389424	16	+	26472758	Raji	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.9038437200496547	[386]	[47]	-6	hSpCas9	negative selection	410742
66388426	66388449	16	-	26472758	Raji	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.21454455951376306	[139]	[27]	-2	hSpCas9	negative selection	410743
66389466	66389489	16	-	26472758	Raji	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.3178033150439715	[120]	[34]	3	hSpCas9	negative selection	410744
66390445	66390468	16	-	26472758	Raji	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.5085488600708858	[208]	[68]	5	hSpCas9	negative selection	410745
66390548	66390571	16	+	26472758	Raji	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.6316501044072016	[177]	[63]	6	hSpCas9	negative selection	410746
66392361	66392384	16	+	26472758	Raji	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.08946162737633712	[80]	[19]	0	hSpCas9	negative selection	410747
66379385	66379408	16	+	26472758	Raji	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	-0.10351324712501897	[124]	[26]	-1	hSpCas9	negative selection	410748
66379442	66379465	16	-	26472758	Raji	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-1.2082582966663316	[457]	[45]	-7	hSpCas9	negative selection	410750
66388331	66388354	16	+	26472758	Raji	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.4966579385873614	[338]	[110]	5	hSpCas9	negative selection	410751
66388384	66388407	16	-	26472758	Raji	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.7634291341562383	[131]	[51]	7	hSpCas9	negative selection	410752
66389401	66389424	16	+	26472758	K562	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.39504172817621586	[552]	[354]	-3	hSpCas9	negative selection	601860
66388426	66388449	16	-	26472758	K562	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.9001722533554898	[284]	[448]	7	hSpCas9	negative selection	601861
66389466	66389489	16	-	26472758	K562	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.5859756293027417	[145]	[184]	5	hSpCas9	negative selection	601862
66390445	66390468	16	-	26472758	K562	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.6473209010863733	[387]	[512]	5	hSpCas9	negative selection	601863
66390548	66390571	16	+	26472758	K562	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.08010237278254542	[352]	[314]	0	hSpCas9	negative selection	601864
66392361	66392384	16	+	26472758	K562	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-0.7208158541728766	[245]	[125]	-4	hSpCas9	negative selection	601865
66379385	66379408	16	+	26472758	K562	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.777850927747521	[113]	[164]	6	hSpCas9	negative selection	601866
66379442	66379465	16	-	26472758	K562	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-2.204888673697143	[709]	[129]	-7	hSpCas9	negative selection	601868
66388331	66388354	16	+	26472758	K562	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.870553469269082	[402]	[621]	7	hSpCas9	negative selection	601869
66388384	66388407	16	-	26472758	K562	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.13355667739085209	[268]	[206]	-1	hSpCas9	negative selection	601870
66379415	66379438	16	+	26627737	DLD1	viability	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.16859389514890305	[319]	[190,107,47]	1	hSpCas9	negative selection	794702
66387043	66387066	16	-	26627737	DLD1	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.06047321261613514	[780]	[219,340,212]	0	hSpCas9	negative selection	794703
66388384	66388407	16	-	26627737	DLD1	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.2691023247366725	[743]	[180,375,286]	2	hSpCas9	negative selection	794704
66389419	66389442	16	+	26627737	DLD1	viability	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-2.6626857724420043	[68]	[0,3,4]	-9	hSpCas9	negative selection	794705
66390554	66390577	16	-	26627737	DLD1	viability	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.24553834409622788	[873]	[403,315,260]	2	hSpCas9	negative selection	794706
66392216	66392239	16	-	26627737	DLD1	viability	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.5783291888817745	[193]	[69,41,13]	-5	hSpCas9	negative selection	794707
66379415	66379438	16	+	26627737	GBM cells	viability after 5 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.25505768511096083	[124]	[84,74]	4	hSpCas9	negative selection	877017
66387043	66387066	16	-	26627737	GBM cells	viability after 5 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.28871312829008583	[245]	[93,121]	-4	hSpCas9	negative selection	877018
66388384	66388407	16	-	26627737	GBM cells	viability after 5 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.03896183499338213	[411]	[214,238]	0	hSpCas9	negative selection	877019
66389419	66389442	16	+	26627737	GBM cells	viability after 5 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-1.364120530948108	[23]	[0,8]	-9	hSpCas9	negative selection	877020
66390554	66390577	16	-	26627737	GBM cells	viability after 5 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.6953804808005535	[303]	[274,252]	8	hSpCas9	negative selection	877021
66392216	66392239	16	-	26627737	GBM cells	viability after 5 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.09822268310909221	[107]	[73,49]	1	hSpCas9	negative selection	877022
66379415	66379438	16	+	26627737	GBM cells	viability after 13 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.06681281097221914	[124]	[75,66]	0	hSpCas9	negative selection	959332
66387043	66387066	16	-	26627737	GBM cells	viability after 13 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.6293440016005994	[245]	[109,66]	-6	hSpCas9	negative selection	959333
66388384	66388407	16	-	26627737	GBM cells	viability after 13 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.28384523067081735	[411]	[291,255]	3	hSpCas9	negative selection	959334
66389419	66389442	16	+	26627737	GBM cells	viability after 13 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-0.13389735511526757	[23]	[23,1]	-2	hSpCas9	negative selection	959335
66390554	66390577	16	-	26627737	GBM cells	viability after 13 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.0255771663682838	[303]	[396,285]	9	hSpCas9	negative selection	959336
66392216	66392239	16	-	26627737	GBM cells	viability after 13 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.42924968388102136	[107]	[95,64]	5	hSpCas9	negative selection	959337
66379415	66379438	16	+	26627737	GBM cells	viability after 21 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.6981384747106189	[124]	[105,113]	7	hSpCas9	negative selection	1041647
66387043	66387066	16	-	26627737	GBM cells	viability after 21 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.09009914986334384	[245]	[135,115]	-1	hSpCas9	negative selection	1041648
66388384	66388407	16	-	26627737	GBM cells	viability after 21 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.28537384457747417	[411]	[265,278]	3	hSpCas9	negative selection	1041649
66389419	66389442	16	+	26627737	GBM cells	viability after 21 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-3.7047292011054975	[23]	[0,0]	-9	hSpCas9	negative selection	1041650
66390554	66390577	16	-	26627737	GBM cells	viability after 21 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.078378174705429	[303]	[330,364]	9	hSpCas9	negative selection	1041651
66392216	66392239	16	-	26627737	GBM cells	viability after 21 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.047399723052501175	[107]	[61,51]	0	hSpCas9	negative selection	1041652
66379415	66379438	16	+	26627737	RPE1	viability after 9 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.6516492840909867	[519]	[284,217]	4	hSpCas9	negative selection	1123962
66387043	66387066	16	-	26627737	RPE1	viability after 9 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.23820569373772374	[663]	[280,198]	1	hSpCas9	negative selection	1123963
66388384	66388407	16	-	26627737	RPE1	viability after 9 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.6516575642576296	[1930]	[324,461]	-5	hSpCas9	negative selection	1123964
66389419	66389442	16	+	26627737	RPE1	viability after 9 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1123965
66390554	66390577	16	-	26627737	RPE1	viability after 9 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.9008722494489654	[911]	[1215,872]	8	hSpCas9	negative selection	1123966
66392216	66392239	16	-	26627737	RPE1	viability after 9 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.5945714875786846	[503]	[131,68]	-4	hSpCas9	negative selection	1123967
66379415	66379438	16	+	26627737	RPE1	viability after 12 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.7583066344310637	[519]	[212,260]	5	hSpCas9	negative selection	1206277
66387043	66387066	16	-	26627737	RPE1	viability after 12 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.1943187082461108	[663]	[169,140]	-1	hSpCas9	negative selection	1206278
66388384	66388407	16	-	26627737	RPE1	viability after 12 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.5380866171541467	[1930]	[332,382]	-4	hSpCas9	negative selection	1206279
66389419	66389442	16	+	26627737	RPE1	viability after 12 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1206280
66390554	66390577	16	-	26627737	RPE1	viability after 12 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.758897121091952	[911]	[1092,549]	8	hSpCas9	negative selection	1206281
66392216	66392239	16	-	26627737	RPE1	viability after 12 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.4522283140450202	[503]	[114,81]	-3	hSpCas9	negative selection	1206282
66379415	66379438	16	+	26627737	RPE1	viability after 15 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	1.1833296452029058	[519]	[358,309]	6	hSpCas9	negative selection	1288592
66387043	66387066	16	-	26627737	RPE1	viability after 15 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.18732446164322214	[663]	[110,216]	-1	hSpCas9	negative selection	1288593
66388384	66388407	16	-	26627737	RPE1	viability after 15 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.6373404947245905	[1930]	[256,441]	-4	hSpCas9	negative selection	1288594
66389419	66389442	16	+	26627737	RPE1	viability after 15 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1288595
66390554	66390577	16	-	26627737	RPE1	viability after 15 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.708499332526042	[911]	[1087,606]	8	hSpCas9	negative selection	1288596
66392216	66392239	16	-	26627737	RPE1	viability after 15 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-1.1000032202664851	[503]	[93,39]	-6	hSpCas9	negative selection	1288597
66379415	66379438	16	+	26627737	RPE1	viability after 18 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.2630731363897815	[519]	[150,186]	1	hSpCas9	negative selection	1370907
66387043	66387066	16	-	26627737	RPE1	viability after 18 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.14832998439722897	[663]	[215,179]	1	hSpCas9	negative selection	1370908
66388384	66388407	16	-	26627737	RPE1	viability after 18 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-1.0640899343276087	[1930]	[226,272]	-6	hSpCas9	negative selection	1370909
66389419	66389442	16	+	26627737	RPE1	viability after 18 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1370910
66390554	66390577	16	-	26627737	RPE1	viability after 18 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.7892712261626287	[911]	[1001,688]	8	hSpCas9	negative selection	1370911
66392216	66392239	16	-	26627737	RPE1	viability after 18 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.801245515479304	[503]	[64,91]	-5	hSpCas9	negative selection	1370912
66379415	66379438	16	+	26627737	HeLa	viability after 8 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.502513600198895	[126]	[132,36,76]	4	hSpCas9	negative selection	1453222
66387043	66387066	16	-	26627737	HeLa	viability after 8 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.9508244855954823	[235]	[191,246,157]	7	hSpCas9	negative selection	1453223
66388384	66388407	16	-	26627737	HeLa	viability after 8 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.04217386988268518	[507]	[162,283,221]	0	hSpCas9	negative selection	1453224
66389419	66389442	16	+	26627737	HeLa	viability after 8 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	6.068257670283625	[0]	[44,0,43]	9	hSpCas9	negative selection	1453225
66390554	66390577	16	-	26627737	HeLa	viability after 8 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.7679433489335572	[548]	[681,281,322]	6	hSpCas9	negative selection	1453226
66392216	66392239	16	-	26627737	HeLa	viability after 8 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	1.4316100284323496	[137]	[223,178,100]	8	hSpCas9	negative selection	1453227
66379415	66379438	16	+	26627737	HeLa	viability after 12 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	1.271033291538006	[126]	[219,104,59]	8	hSpCas9	negative selection	1535537
66387043	66387066	16	-	26627737	HeLa	viability after 12 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.6593622881793075	[235]	[66,168,221]	5	hSpCas9	negative selection	1535538
66388384	66388407	16	-	26627737	HeLa	viability after 12 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.638996373972998	[507]	[144,340,487]	5	hSpCas9	negative selection	1535539
66389419	66389442	16	+	26627737	HeLa	viability after 12 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	6.60142792848411	[0]	[124,0,0]	9	hSpCas9	negative selection	1535540
66390554	66390577	16	-	26627737	HeLa	viability after 12 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.9955251111899881	[548]	[424,388,548]	7	hSpCas9	negative selection	1535541
66392216	66392239	16	-	26627737	HeLa	viability after 12 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	1.3668802924676537	[137]	[127,200,105]	8	hSpCas9	negative selection	1535542
66379415	66379438	16	+	26627737	HeLa	viability after 15 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	2.0098040861067124	[126]	[275,148,197]	9	hSpCas9	negative selection	1617852
66387043	66387066	16	-	26627737	HeLa	viability after 15 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.5046060255752216	[235]	[157,109,140]	4	hSpCas9	negative selection	1617853
66388384	66388407	16	-	26627737	HeLa	viability after 15 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.22104139604001538	[507]	[252,240,227]	2	hSpCas9	negative selection	1617854
66389419	66389442	16	+	26627737	HeLa	viability after 15 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	5.062739488466195	[0]	[0,1,39]	9	hSpCas9	negative selection	1617855
66390554	66390577	16	-	26627737	HeLa	viability after 15 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.0934746385397085	[548]	[456,291,698]	7	hSpCas9	negative selection	1617856
66392216	66392239	16	-	26627737	HeLa	viability after 15 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.9434502367744096	[137]	[152,56,113]	7	hSpCas9	negative selection	1617857
66379415	66379438	16	+	26627737	HeLa	viability after 18 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	1.9944495046802935	[126]	[177,126,197]	9	hSpCas9	negative selection	1700167
66387043	66387066	16	-	26627737	HeLa	viability after 18 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.4452949596022099	[235]	[96,88,140]	3	hSpCas9	negative selection	1700168
66388384	66388407	16	-	26627737	HeLa	viability after 18 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.18616776998344164	[507]	[162,193,227]	1	hSpCas9	negative selection	1700169
66389419	66389442	16	+	26627737	HeLa	viability after 18 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	5.095303932680515	[0]	[0,1,39]	9	hSpCas9	negative selection	1700170
66390554	66390577	16	-	26627737	HeLa	viability after 18 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.0971106679458862	[548]	[303,247,698]	7	hSpCas9	negative selection	1700171
66392216	66392239	16	-	26627737	HeLa	viability after 18 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.9156140439820382	[137]	[97,47,113]	7	hSpCas9	negative selection	1700172
66379415	66379438	16	+	26627737	HCT116	viability after 6 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	-1.5004510907866186	[383]	[1,31]	-7	hSpCas9	negative selection	1782482
66387043	66387066	16	-	26627737	HCT116	viability after 6 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-2.6321656628965053	[601]	[22,10]	-9	hSpCas9	negative selection	1782483
66388384	66388407	16	-	26627737	HCT116	viability after 6 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.03578402453794924	[672]	[186,56]	0	hSpCas9	negative selection	1782484
66389419	66389442	16	+	26627737	HCT116	viability after 6 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1782485
66390554	66390577	16	-	26627737	HCT116	viability after 6 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.3336622548534343	[1229]	[1002,202]	7	hSpCas9	negative selection	1782486
66392216	66392239	16	-	26627737	HCT116	viability after 6 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	1.3133684709174307	[203]	[2,121]	7	hSpCas9	negative selection	1782487
66379415	66379438	16	+	26627737	HCT116	viability after 8 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	-0.5305647710428184	[349]	[149,130,119]	-6	hSpCas9	negative selection	1864797
66387043	66387066	16	-	26627737	HCT116	viability after 8 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-1.0250914896566754	[369]	[76,111,110]	-8	hSpCas9	negative selection	1864798
66388384	66388407	16	-	26627737	HCT116	viability after 8 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.8204985369197357	[712]	[191,263,210]	-7	hSpCas9	negative selection	1864799
66389419	66389442	16	+	26627737	HCT116	viability after 8 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-2.7817947346101386	[83]	[0,4,13]	-9	hSpCas9	negative selection	1864800
66390554	66390577	16	-	26627737	HCT116	viability after 8 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.1815612586963617	[342]	[526,426,334]	8	hSpCas9	negative selection	1864801
66392216	66392239	16	-	26627737	HCT116	viability after 8 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.07529903833012741	[178]	[120,120,39]	-1	hSpCas9	negative selection	1864802
66379415	66379438	16	+	26627737	HCT116	viability after 9 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	-0.8222158022080829	[383]	[100,23]	-5	hSpCas9	negative selection	1947112
66387043	66387066	16	-	26627737	HCT116	viability after 9 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-1.6620779691859178	[601]	[47,52]	-8	hSpCas9	negative selection	1947113
66388384	66388407	16	-	26627737	HCT116	viability after 9 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	1.422256480831861	[672]	[470,489]	8	hSpCas9	negative selection	1947114
66389419	66389442	16	+	26627737	HCT116	viability after 9 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	5.439248872331309	[0]	[5,15]	9	hSpCas9	negative selection	1947115
66390554	66390577	16	-	26627737	HCT116	viability after 9 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	-0.32821418492433796	[1229]	[355,186]	-2	hSpCas9	negative selection	1947116
66392216	66392239	16	-	26627737	HCT116	viability after 9 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.8111444107431847	[203]	[63,4]	-5	hSpCas9	negative selection	1947117
66379415	66379438	16	+	26627737	HCT116	viability after 12 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	-0.4204037007109679	[349]	[113,121,177]	-4	hSpCas9	negative selection	2029427
66387043	66387066	16	-	26627737	HCT116	viability after 12 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.5737124537278966	[369]	[151,86,149]	-6	hSpCas9	negative selection	2029428
66388384	66388407	16	-	26627737	HCT116	viability after 12 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.6145863220413537	[712]	[161,267,311]	-6	hSpCas9	negative selection	2029429
66389419	66389442	16	+	26627737	HCT116	viability after 12 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-2.2485209970718296	[83]	[17,4,3]	-9	hSpCas9	negative selection	2029430
66390554	66390577	16	-	26627737	HCT116	viability after 12 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.20207245698744	[342]	[516,366,349]	8	hSpCas9	negative selection	2029431
66392216	66392239	16	-	26627737	HCT116	viability after 12 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.21568450338588008	[178]	[36,126,83]	-2	hSpCas9	negative selection	2029432
66379415	66379438	16	+	26627737	HCT116	viability after 15 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	-1.123180240672459	[349]	[71,79,121]	-8	hSpCas9	negative selection	2111742
66387043	66387066	16	-	26627737	HCT116	viability after 15 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.7886829972852355	[369]	[167,125,80]	-7	hSpCas9	negative selection	2111743
66388384	66388407	16	-	26627737	HCT116	viability after 15 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.40081039421051656	[712]	[308,285,334]	-4	hSpCas9	negative selection	2111744
66389419	66389442	16	+	26627737	HCT116	viability after 15 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-0.8386463431283044	[83]	[26,32,20]	-7	hSpCas9	negative selection	2111745
66390554	66390577	16	-	26627737	HCT116	viability after 15 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.8848729553379429	[342]	[391,447,255]	7	hSpCas9	negative selection	2111746
66392216	66392239	16	-	26627737	HCT116	viability after 15 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.0041663778266548546	[178]	[91,117,97]	0	hSpCas9	negative selection	2111747
66379415	66379438	16	+	26627737	HCT116	viability after 18 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	-0.5470855783254395	[349]	[22,88,242]	-5	hSpCas9	negative selection	2194057
66387043	66387066	16	-	26627737	HCT116	viability after 18 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.42068382255325487	[369]	[402,174,139]	3	hSpCas9	negative selection	2194058
66388384	66388407	16	-	26627737	HCT116	viability after 18 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.7352151963299127	[712]	[284,116,225]	-6	hSpCas9	negative selection	2194059
66389419	66389442	16	+	26627737	HCT116	viability after 18 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-0.8275665077295649	[83]	[40,20,5]	-6	hSpCas9	negative selection	2194060
66390554	66390577	16	-	26627737	HCT116	viability after 18 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	1.2570287041357564	[342]	[534,381,266]	8	hSpCas9	negative selection	2194061
66392216	66392239	16	-	26627737	HCT116	viability after 18 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.25318231178389095	[178]	[22,159,26]	-2	hSpCas9	negative selection	2194062
66373648	66373671	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGTGATCCACCCGCCACAG	CDH5	ENSG00000179776	2.620239326481035	[29,127]	[21,200]	8	dCas9-VP64	positive selection	2423401
66373648	66373671	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGTGATCCACCCGCCACAG	CDH5	ENSG00000179776	0.43799384050484425	[187,212]	[110,67]	3	dCas9-VP64	positive selection	2518656
66387039	66387062	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGGCCTGTGTTCACGCATCGG	CDH5	ENSG00000179776	0.2653750560727534	[3,3]	[3,3]	5	hSpCas9	positive selection	2978093
66389432	66389455	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATGCCCAGGGCCTCCGGGGGG	CDH5	ENSG00000179776	-0.7553900408648585	[2,3]	[2,0]	-8	hSpCas9	positive selection	2978094
66389402	66389425	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.07180300381965948	[2,3]	[3,1]	-1	hSpCas9	positive selection	2978095
66388379	66388402	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGGTACATGACAGAGGCGTGG	CDH5	ENSG00000179776	0.027051329085111653	[2,2]	[2,1]	0	hSpCas9	positive selection	2978096
66387039	66387062	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGGCCTGTGTTCACGCATCGG	CDH5	ENSG00000179776	0.4729557426995791	[3,3]	[4,2]	7	hSpCas9	positive selection	3045951
66389432	66389455	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATGCCCAGGGCCTCCGGGGGG	CDH5	ENSG00000179776	0.7594990696781556	[2,2]	[3,3]	9	hSpCas9	positive selection	3045952
66389402	66389425	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.23316702539352374	[2,2]	[3,0]	-3	hSpCas9	positive selection	3045953
66388379	66388402	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGGTACATGACAGAGGCGTGG	CDH5	ENSG00000179776	-0.1272443755477659	[2,2]	[1,0]	-2	hSpCas9	positive selection	3045954
66387043	66387066		-	24336571	A375	resistance to PLX after 7 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.02733766065929599	[10,13]	[9,14]	1	hSpCas9	positive selection	3104514
66379349	66379372		+	24336571	A375	resistance to PLX after 7 days	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.5528112142676055	[22,20]	[31,33]	9	hSpCas9	positive selection	3104515
66379358	66379381		-	24336571	A375	resistance to PLX after 7 days	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.13817244789920702	[1,1]	[1,1]	4	hSpCas9	positive selection	3104516
66387020	66387043		+	24336571	A375	resistance to PLX after 7 days	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.17452305590916817	[24,24]	[19,23]	-5	hSpCas9	positive selection	3104517
66387043	66387066		-	24336571	A375	resistance to PLX after 14 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.15827623372287114	[12,17]	[4,6]	-2	hSpCas9	positive selection	3162307
66379349	66379372		+	24336571	A375	resistance to PLX after 14 days	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.476516266222645	[29,20]	[16,14]	4	hSpCas9	positive selection	3162308
66379358	66379381		-	24336571	A375	resistance to PLX after 14 days	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	1.002191896545204	[1,1]	[1,1]	7	hSpCas9	positive selection	3162309
66387020	66387043		+	24336571	A375	resistance to PLX after 14 days	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.5824866860049178	[28,24]	[8,6]	-7	hSpCas9	positive selection	3162310
66387043	66387066		-	24336571	A375	viability after 7 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.27801087606089847	[15]	[10,13]	-4	hSpCas9	negative selection	3220100
66379349	66379372		+	24336571	A375	viability after 7 days	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.7750440317221762	[13]	[22,20]	9	hSpCas9	negative selection	3220101
66379358	66379381		-	24336571	A375	viability after 7 days	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-0.10328697673480747	[1]	[1,1]	-1	hSpCas9	negative selection	3220102
66387020	66387043		+	24336571	A375	viability after 7 days	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.8517842368695887	[13]	[24,24]	9	hSpCas9	negative selection	3220103
66387043	66387066		-	24336571	A375	viability after 14 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.023947633319716333	[15]	[12,17]	0	hSpCas9	negative selection	3277893
66379349	66379372		+	24336571	A375	viability after 14 days	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.9849470264637787	[13]	[29,20]	9	hSpCas9	negative selection	3277894
66379358	66379381		-	24336571	A375	viability after 14 days	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-0.15217361479204605	[1]	[1,1]	-2	hSpCas9	negative selection	3277895
66387020	66387043		+	24336571	A375	viability after 14 days	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.9879012621333415	[13]	[28,24]	9	hSpCas9	negative selection	3277896
66387020	66387043	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.44099087298146866	[142,81]	[0,0]	2	hSpCas9	positive selection	3342330
66387043	66387066	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.4314154846751641	[178,233]	[0,0]	-3	hSpCas9	positive selection	3342331
66379349	66379372	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	-1.2226917484468698	[365,347]	[0,0]	-7	hSpCas9	positive selection	3342332
66389403	66389426	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-1.4773834087800033	[425,425]	[0,0]	-8	hSpCas9	positive selection	3361563
66389398	66389421	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	2.1280431945008687	[34,34]	[0,0]	7	hSpCas9	positive selection	3361564
66387038	66387061	16	+	26780180	HT29	viability (Avana library 4 designs)	ACTGGCCTGTGTTCACGCATCGG	CDH5	ENSG00000179776	0.913723509802331	[]	[]	3	hSpCas9	negative selection	3414404
66389431	66389454	16	+	26780180	HT29	viability (Avana library 4 designs)	AGATGCCCAGGGCCTCCGGGGGG	CDH5	ENSG00000179776	1.56629564311062	[]	[]	6	hSpCas9	negative selection	3414405
66389401	66389424	16	+	26780180	HT29	viability (Avana library 4 designs)	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	2.20894277794845	[]	[]	7	hSpCas9	negative selection	3414406
66388379	66388402	16	-	26780180	HT29	viability (Avana library 4 designs)	TTTGGTACATGACAGAGGCGTGG	CDH5	ENSG00000179776	1.86225638739534	[]	[]	7	hSpCas9	negative selection	3414407
66387038	66387061	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGGCCTGTGTTCACGCATCGG	CDH5	ENSG00000179776	3.27480174813543	[]	[]	5	hSpCas9	negative selection	3490903
66388379	66388402	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGGTACATGACAGAGGCGTGG	CDH5	ENSG00000179776	3.6359475579493	[]	[]	6	hSpCas9	negative selection	3490904
66389401	66389424	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	1.49779325311304	[]	[]	2	hSpCas9	negative selection	3490905
66389431	66389454	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGCCCAGGGCCTCCGGGGGG	CDH5	ENSG00000179776	1.04620637662607	[]	[]	1	hSpCas9	negative selection	3490906
66388331	66388354	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	2.00964657562568	[]	[]	3	hSpCas9	negative selection	3490907
66392159	66392182	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATACAGCTTCATCGTCGAGG	CDH5	ENSG00000179776	0.844779135346431	[]	[]	1	hSpCas9	negative selection	3490908
66387038	66387061	16	+	26780180	A375	viability (Avana lentiGuide)	ACTGGCCTGTGTTCACGCATCGG	CDH5	ENSG00000179776	3.3000638418515	[]	[]	3	hSpCas9	negative selection	3599562
66388379	66388402	16	-	26780180	A375	viability (Avana lentiGuide)	TTTGGTACATGACAGAGGCGTGG	CDH5	ENSG00000179776	7.01750602589321	[]	[]	5	hSpCas9	negative selection	3599563
66389401	66389424	16	+	26780180	A375	viability (Avana lentiGuide)	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	15.4844805402097	[]	[]	8	hSpCas9	negative selection	3599564
66389431	66389454	16	+	26780180	A375	viability (Avana lentiGuide)	AGATGCCCAGGGCCTCCGGGGGG	CDH5	ENSG00000179776	10.2266111137696	[]	[]	7	hSpCas9	negative selection	3599565
66388331	66388354	16	+	26780180	A375	viability (Avana lentiGuide)	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.856929938712695	[]	[]	1	hSpCas9	negative selection	3599566
66392159	66392182	16	+	26780180	A375	viability (Avana lentiGuide)	GCAATACAGCTTCATCGTCGAGG	CDH5	ENSG00000179776	-4.90469098054845	[]	[]	-8	hSpCas9	negative selection	3599567
66387038	66387061	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGGCCTGTGTTCACGCATCGG	CDH5	ENSG00000179776	0.1893815220966183	[5]	[7,4]	5	hSpCas9	positive selection	3708221
66388379	66388402	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGGTACATGACAGAGGCGTGG	CDH5	ENSG00000179776	0.2673056140348551	[4]	[5,5]	7	hSpCas9	positive selection	3708222
66389401	66389424	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.24768622765053722	[4]	[5,1]	-4	hSpCas9	positive selection	3708223
66389431	66389454	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGCCCAGGGCCTCCGGGGGG	CDH5	ENSG00000179776	0.22545834449673594	[5]	[5,6]	6	hSpCas9	positive selection	3708224
66388331	66388354	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.12208415784474513	[6]	[6,6]	3	hSpCas9	positive selection	3708225
66392159	66392182	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATACAGCTTCATCGTCGAGG	CDH5	ENSG00000179776	-0.062439555949764844	[4]	[4,3]	-1	hSpCas9	positive selection	3708226
66387038	66387061	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGGCCTGTGTTCACGCATCGG	CDH5	ENSG00000179776	0.04058533012417459	[5]	[4,5]	0	hSpCas9	positive selection	3816828
66388379	66388402	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGGTACATGACAGAGGCGTGG	CDH5	ENSG00000179776	-0.3743163707494376	[4]	[4,0]	-5	hSpCas9	positive selection	3816829
66389401	66389424	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.6271988987843635	[4]	[0,4]	-7	hSpCas9	positive selection	3816830
66389431	66389454	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGCCCAGGGCCTCCGGGGGG	CDH5	ENSG00000179776	-0.16279630235012837	[5]	[2,4]	-2	hSpCas9	positive selection	3816831
66388331	66388354	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.2415878333610474	[6]	[7,6]	6	hSpCas9	positive selection	3816832
66392159	66392182	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATACAGCTTCATCGTCGAGG	CDH5	ENSG00000179776	0.058963495254434686	[5]	[5,3]	1	hSpCas9	positive selection	3816833
66387043	66387066	16	-	26780180	A375	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	1.39438023250512	[]	[]	7	hSpCas9	negative selection	3924996
66379349	66379372	16	+	26780180	A375	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	-0.224514879246369	[]	[]	-6	hSpCas9	negative selection	3924997
66389398	66389421	16	+	26780180	A375	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.24483977906117	[]	[]	0	hSpCas9	negative selection	3924998
66379358	66379381	16	-	26780180	A375	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.0506234391775587	[]	[]	0	hSpCas9	negative selection	3924999
66387020	66387043	16	+	26780180	A375	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	1.29834995190241	[]	[]	7	hSpCas9	negative selection	3925000
66389403	66389426	16	-	26780180	A375	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	1.61192078560324	[]	[]	8	hSpCas9	negative selection	3925001
66387043	66387066	16	-	26780180	HT29	viability (GeCKOv2 library)	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.339386922654335	[]	[]	0	hSpCas9	negative selection	4032962
66379349	66379372	16	+	26780180	HT29	viability (GeCKOv2 library)	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.102757529396034	[]	[]	0	hSpCas9	negative selection	4032963
66389398	66389421	16	+	26780180	HT29	viability (GeCKOv2 library)	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.282666257495897	[]	[]	0	hSpCas9	negative selection	4032964
66379358	66379381	16	-	26780180	HT29	viability (GeCKOv2 library)	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.0788571339295289	[]	[]	0	hSpCas9	negative selection	4032965
66387020	66387043	16	+	26780180	HT29	viability (GeCKOv2 library)	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	1.44383594191772	[]	[]	7	hSpCas9	negative selection	4032966
66389403	66389426	16	-	26780180	HT29	viability (GeCKOv2 library)	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	2.61158478769104	[]	[]	9	hSpCas9	negative selection	4032967
66387043	66387066	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.2103661901854799	[3]	[3,2]	5	hSpCas9	positive selection	4126539
66379349	66379372	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.23546558512262883	[4]	[2,3]	6	hSpCas9	positive selection	4126540
66379358	66379381	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.5195369921000899	[0]	[0,0]	9	hSpCas9	positive selection	4126541
66387020	66387043	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.07537254914856548	[4]	[2,2]	2	hSpCas9	positive selection	4126542
66387043	66387066	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.14762053303836906	[3]	[4,1,1,0]	1	hSpCas9	positive selection	4190561
66379349	66379372	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.9422088954145004	[4]	[4,3,5,2]	6	hSpCas9	positive selection	4190562
66379358	66379381	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-0.03288094966354249	[2]	[2,0,0,0]	0	hSpCas9	positive selection	4190563
66387020	66387043	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	1.2010087622157708	[4]	[5,1,4,4]	8	hSpCas9	positive selection	4190564
66387020	66387043	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.44401437831718965	[2]	[2,3]	8	hSpCas9	positive selection	4262380
66387043	66387066	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.31920981584427494	[4]	[3,4]	6	hSpCas9	positive selection	4262381
66379349	66379372	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2786215261830426	[4]	[4,3]	5	hSpCas9	positive selection	4262382
66389403	66389426	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5308798572345864	[4]	[2,1]	-8	hSpCas9	positive selection	4326658
66379358	66379381	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.2725891090236312	[0]	[0,0]	5	hSpCas9	positive selection	4326659
66389398	66389421	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.6446690456112831	[0]	[1,0]	9	hSpCas9	positive selection	4326660
66379463	66379485	16	+	27760321	OCIAML3	viability	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	-0.1414772963845281	[217,140]	[78,185]	-1	hSpCas9	negative selection	4387926
66387021	66387043	16	+	27760321	OCIAML3	viability	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.675392547104835	[218,200]	[243,285]	7	hSpCas9	negative selection	4387927
66388426	66388448	16	-	27760321	OCIAML3	viability	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.19077308449986585	[13,8]	[0,21]	2	hSpCas9	negative selection	4387928
66390510	66390532	16	+	27760321	OCIAML3	viability	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	0.30325290123058546	[451,401]	[443,368]	3	hSpCas9	negative selection	4387929
66392194	66392216	16	-	27760321	OCIAML3	viability	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	-0.10057043344439998	[562,499]	[324,467]	-1	hSpCas9	negative selection	4387930
66379463	66379485	16	+	27760321	OCIAML2	viability	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	-0.10112760937818388	[217,140]	[110,162]	-1	hSpCas9	negative selection	4471389
66387021	66387043	16	+	27760321	OCIAML2	viability	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.261091185276054	[218,200]	[139,143]	-3	hSpCas9	negative selection	4471390
66388426	66388448	16	-	27760321	OCIAML2	viability	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.28341884766018755	[13,8]	[8,13]	4	hSpCas9	negative selection	4471391
66390510	66390532	16	+	27760321	OCIAML2	viability	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	0.3456759812922149	[451,401]	[417,464]	5	hSpCas9	negative selection	4471392
66392194	66392216	16	-	27760321	OCIAML2	viability	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.37112692071558717	[562,499]	[439,706]	5	hSpCas9	negative selection	4471393
66379463	66379485	16	+	27760321	MV411	viability	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.39764954022068166	[217,140]	[164,136]	3	hSpCas9	negative selection	4554852
66387021	66387043	16	+	27760321	MV411	viability	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-1.6422912939615224	[218,200]	[23,74]	-8	hSpCas9	negative selection	4554853
66388426	66388448	16	-	27760321	MV411	viability	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-2.9027219218029927	[13,8]	[0,0]	-9	hSpCas9	negative selection	4554854
66390510	66390532	16	+	27760321	MV411	viability	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	0.3915914202056664	[451,401]	[229,577]	3	hSpCas9	negative selection	4554855
66392194	66392216	16	-	27760321	MV411	viability	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.02072786643032065	[562,499]	[174,625]	0	hSpCas9	negative selection	4554856
66379463	66379485	16	+	27760321	HL60	viability	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.10413374797841302	[217,140]	[199,107]	1	hSpCas9	negative selection	4638315
66387021	66387043	16	+	27760321	HL60	viability	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.3134000736991356	[218,200]	[121,154]	-4	hSpCas9	negative selection	4638316
66388426	66388448	16	-	27760321	HL60	viability	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.8966195192903781	[13,8]	[24,8]	8	hSpCas9	negative selection	4638317
66390510	66390532	16	+	27760321	HL60	viability	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	0.3088855312270015	[451,401]	[544,310]	4	hSpCas9	negative selection	4638318
66392194	66392216	16	-	27760321	HL60	viability	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.19010785467213953	[562,499]	[528,457]	2	hSpCas9	negative selection	4638319
66379463	66379485	16	+	27760321	HT1080	viability	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	1.2515504363769416	[140,109]	[45,198]	6	hSpCas9	negative selection	4721778
66387021	66387043	16	+	27760321	HT1080	viability	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.8637252053075535	[200,156]	[0,80]	-4	hSpCas9	negative selection	4721779
66388426	66388448	16	-	27760321	HT1080	viability	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	1.2905674542542034	[8,6]	[13,0]	7	hSpCas9	negative selection	4721780
66390510	66390532	16	+	27760321	HT1080	viability	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	0.5768676396887115	[401,313]	[143,287]	3	hSpCas9	negative selection	4721781
66392194	66392216	16	-	27760321	HT1080	viability	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.08994872631525119	[499,389]	[244,126]	0	hSpCas9	negative selection	4721782
66379463	66379485	16	+	27760321	HT29	viability after 7 days	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.8154398939951254	[140,109]	[333,221,301]	9	hSpCas9	negative selection	4805241
66387021	66387043	16	+	27760321	HT29	viability after 7 days	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.7453540704985009	[200,156]	[212,88,120]	-8	hSpCas9	negative selection	4805242
66388426	66388448	16	-	27760321	HT29	viability after 7 days	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.8249881487303252	[8,6]	[58,0,0]	9	hSpCas9	negative selection	4805243
66390510	66390532	16	+	27760321	HT29	viability after 7 days	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	-0.1569531510494572	[401,313]	[310,516,395]	-2	hSpCas9	negative selection	4805244
66392194	66392216	16	-	27760321	HT29	viability after 7 days	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.23130491515364765	[499,389]	[638,691,677]	3	hSpCas9	negative selection	4805245
66379463	66379485	16	+	27760321	HT29	viability after 25 days	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.663931136555407	[140,109]	[141,228,325]	7	hSpCas9	negative selection	4888704
66387021	66387043	16	+	27760321	HT29	viability after 25 days	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.32660924410489667	[200,156]	[168,102,222]	-3	hSpCas9	negative selection	4888705
66388426	66388448	16	-	27760321	HT29	viability after 25 days	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.6636611299126383	[8,6]	[8,0,35]	7	hSpCas9	negative selection	4888706
66390510	66390532	16	+	27760321	HT29	viability after 25 days	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	-0.2838284319308734	[401,313]	[201,358,468]	-3	hSpCas9	negative selection	4888707
66392194	66392216	16	-	27760321	HT29	viability after 25 days	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.6175927497840075	[499,389]	[572,935,850]	7	hSpCas9	negative selection	4888708
66379463	66379485	16	+	27760321	HT29	viability after 22 days	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.40809085847077586	[140,109]	[238,172,163]	4	hSpCas9	negative selection	4972167
66387021	66387043	16	+	27760321	HT29	viability after 22 days	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.6427126076779848	[200,156]	[137,73,185]	-5	hSpCas9	negative selection	4972168
66388426	66388448	16	-	27760321	HT29	viability after 22 days	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-1.1104104410015108	[8,6]	[0,0,10]	-7	hSpCas9	negative selection	4972169
66390510	66390532	16	+	27760321	HT29	viability after 22 days	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	0.05659363510535889	[401,313]	[279,624,389]	0	hSpCas9	negative selection	4972170
66392194	66392216	16	-	27760321	HT29	viability after 22 days	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.806851756565004	[499,389]	[988,529,1180]	8	hSpCas9	negative selection	4972171
66379463	66379485	16	+	27760321	HT29	viability after 19 days	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.23449018617329642	[140,109]	[224,162,125]	2	hSpCas9	negative selection	5055630
66387021	66387043	16	+	27760321	HT29	viability after 19 days	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.3640136755930943	[200,156]	[217,182,379]	3	hSpCas9	negative selection	5055631
66388426	66388448	16	-	27760321	HT29	viability after 19 days	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	2.302633306597232	[8,6]	[10,0,116]	9	hSpCas9	negative selection	5055632
66390510	66390532	16	+	27760321	HT29	viability after 19 days	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	-0.3245182076405367	[401,313]	[376,202,402]	-3	hSpCas9	negative selection	5055633
66392194	66392216	16	-	27760321	HT29	viability after 19 days	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.7919691528903701	[499,389]	[655,1073,888]	7	hSpCas9	negative selection	5055634
66379463	66379485	16	+	27760321	HT29	viability after 16 days	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.35762516457163485	[140,109]	[140,141,253]	4	hSpCas9	negative selection	5139093
66387021	66387043	16	+	27760321	HT29	viability after 16 days	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.09912381119301283	[200,156]	[90,218,240]	-1	hSpCas9	negative selection	5139094
66388426	66388448	16	-	27760321	HT29	viability after 16 days	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.018440950118991495	[8,6]	[25,0,1]	0	hSpCas9	negative selection	5139095
66390510	66390532	16	+	27760321	HT29	viability after 16 days	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	0.012259439540203624	[401,313]	[398,494,314]	0	hSpCas9	negative selection	5139096
66392194	66392216	16	-	27760321	HT29	viability after 16 days	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.19563557087856326	[499,389]	[638,296,787]	2	hSpCas9	negative selection	5139097
66379463	66379485	16	+	27760321	HT29	viability after 13 days	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.2816140577886632	[140,109]	[175,230,126]	3	hSpCas9	negative selection	5222556
66387021	66387043	16	+	27760321	HT29	viability after 13 days	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.6340171538730506	[200,156]	[98,159,141]	-6	hSpCas9	negative selection	5222557
66388426	66388448	16	-	27760321	HT29	viability after 13 days	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.41364100311778795	[8,6]	[14,0,4]	-5	hSpCas9	negative selection	5222558
66390510	66390532	16	+	27760321	HT29	viability after 13 days	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	-0.02709113608716863	[401,313]	[421,482,322]	0	hSpCas9	negative selection	5222559
66392194	66392216	16	-	27760321	HT29	viability after 13 days	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.25315473962890206	[499,389]	[466,661,710]	3	hSpCas9	negative selection	5222560
66379463	66379485	16	+	27760321	HT29	viability after 10 days	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	0.3340578715652003	[140,109]	[237,128,222]	4	hSpCas9	negative selection	5306019
66387021	66387043	16	+	27760321	HT29	viability after 10 days	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-1.180377967250781	[200,156]	[160,73,60]	-8	hSpCas9	negative selection	5306020
66388426	66388448	16	-	27760321	HT29	viability after 10 days	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-3.3198702585953583	[8,6]	[0,0,0]	-9	hSpCas9	negative selection	5306021
66390510	66390532	16	+	27760321	HT29	viability after 10 days	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	-0.48215135882613763	[401,313]	[326,296,334]	-5	hSpCas9	negative selection	5306022
66392194	66392216	16	-	27760321	HT29	viability after 10 days	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.19113333113190817	[499,389]	[376,733,790]	2	hSpCas9	negative selection	5306023
66379463	66379485	16	+	27760321	MOLM13	viability	CCGGCGCCAAAAGAGAGATTGG	CDH5	ENSG00000179776	1.6468833699946184	[217,140]	[512,141]	9	hSpCas9	negative selection	5389482
66387021	66387043	16	+	27760321	MOLM13	viability	TCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.02125071424214031	[218,200]	[150,93]	0	hSpCas9	negative selection	5389483
66388426	66388448	16	-	27760321	MOLM13	viability	CACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	1.9352040843753713	[13,8]	[51,0]	9	hSpCas9	negative selection	5389484
66390510	66390532	16	+	27760321	MOLM13	viability	ATCTTGCGGGGCGACTACCAGG	CDH5	ENSG00000179776	-0.09386968657021762	[451,401]	[51,372]	0	hSpCas9	negative selection	5389485
66392194	66392216	16	-	27760321	MOLM13	viability	CTCATGTATCGGAGGTCGATGG	CDH5	ENSG00000179776	0.7910346606839503	[562,499]	[355,655]	5	hSpCas9	negative selection	5389486
66366933	66366956	16	+	27661255	K562	viability	GCACCCAGAGGTAGTGCCAAGGG	CDH5	ENSG00000179776	-0.3017687228344572	[32,56]	[43,15]	-7	dCas9-KRAB	negative selection	5469820
66387020	66387043	16	+	27260156	BXPC3	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.01954441696018505	[349]	[362,316,421,385]	0	hSpCas9	negative selection	5534840
66387043	66387066	16	-	27260156	BXPC3	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.32535835985600037	[1119]	[727,851,1077,1127]	-6	hSpCas9	negative selection	5534841
66379349	66379372	16	+	27260156	BXPC3	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.23298424979047794	[1219]	[1346,1459,1583,1631]	5	hSpCas9	negative selection	5534842
66389403	66389426	16	-	27260156	BXPC3	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.479553666970308	[1397]	[962,1020,1050,1177]	-8	hSpCas9	negative selection	5599118
66379358	66379381	16	-	27260156	BXPC3	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.483479608184286	[3]	[1,0,0,1]	-9	hSpCas9	negative selection	5599119
66389398	66389421	16	+	27260156	BXPC3	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.7642932398976963	[41]	[96,84,70,36]	9	hSpCas9	negative selection	5599120
66387020	66387043	16	+	27260156	A673	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.009236484876019246	[349]	[424,350,353,549]	0	hSpCas9	negative selection	5656091
66387043	66387066	16	-	27260156	A673	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.1442463088726973	[1119]	[1435,1210,1088,1151]	-4	hSpCas9	negative selection	5656092
66379349	66379372	16	+	27260156	A673	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.23460425097886417	[1219]	[1847,1668,1784,1596]	5	hSpCas9	negative selection	5656093
66389403	66389426	16	-	27260156	A673	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.6265508782055188	[1397]	[1079,1011,1245,1003]	-9	hSpCas9	negative selection	5720369
66379358	66379381	16	-	27260156	A673	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.2631622979798074	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	5720370
66389398	66389421	16	+	27260156	A673	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.17468796634168715	[41]	[35,31,17,94]	-4	hSpCas9	negative selection	5720371
66387020	66387043	16	+	27260156	A375	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.040105011465204066	[349]	[375,538,352,426]	0	hSpCas9	negative selection	5777342
66387043	66387066	16	-	27260156	A375	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.3181544284719362	[1119]	[1261,1071,752,1103]	-4	hSpCas9	negative selection	5777343
66379349	66379372	16	+	27260156	A375	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.4413723504735758	[1219]	[1812,1989,2010,1925]	6	hSpCas9	negative selection	5777344
66389403	66389426	16	-	27260156	A375	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.24773295655258143	[1397]	[1353,1155,1192,1719]	-4	hSpCas9	negative selection	5841620
66379358	66379381	16	-	27260156	A375	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.222606980940027	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	5841621
66389398	66389421	16	+	27260156	A375	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.2606074122615265	[41]	[39,8,85,25]	-4	hSpCas9	negative selection	5841622
66387020	66387043	16	+	27260156	COLO741	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.12583076629222284	[349]	[458,423,353]	-3	hSpCas9	negative selection	5898593
66387043	66387066	16	-	27260156	COLO741	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.1966319298169763	[1119]	[1180,1381,1179]	-4	hSpCas9	negative selection	5898594
66379349	66379372	16	+	27260156	COLO741	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.3053191289786388	[1219]	[2035,1871,1878]	6	hSpCas9	negative selection	5898595
66389403	66389426	16	-	27260156	COLO741	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.3405779303690444	[1397]	[1517,1397,1327]	-6	hSpCas9	negative selection	5962871
66379358	66379381	16	-	27260156	COLO741	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.3524737808476335	[3]	[0,0,0]	-9	hSpCas9	negative selection	5962872
66389398	66389421	16	+	27260156	COLO741	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.7999683677517302	[41]	[153,105,29]	9	hSpCas9	negative selection	5962873
66387020	66387043	16	+	27260156	CAL120	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.12125614132817575	[349]	[521,530,376]	1	hSpCas9	negative selection	6019844
66387043	66387066	16	-	27260156	CAL120	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.04643379140158843	[1119]	[1640,1230,1474]	0	hSpCas9	negative selection	6019845
66379349	66379372	16	+	27260156	CAL120	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.23272973181850376	[1219]	[1625,1791,1906]	3	hSpCas9	negative selection	6019846
66389403	66389426	16	-	27260156	CAL120	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.7755765612898533	[1397]	[1035,929,1083]	-8	hSpCas9	negative selection	6084122
66379358	66379381	16	-	27260156	CAL120	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.3152262340772953	[3]	[0,0,0]	-9	hSpCas9	negative selection	6084123
66389398	66389421	16	+	27260156	CAL120	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.11082735131270649	[41]	[40,50,51]	-2	hSpCas9	negative selection	6084124
66387020	66387043	16	+	27260156	CADOES1	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.19852374444777782	[349]	[358,390,274,472]	3	hSpCas9	negative selection	6141095
66387043	66387066	16	-	27260156	CADOES1	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.4015022250544886	[1119]	[786,713,769,886]	-6	hSpCas9	negative selection	6141096
66379349	66379372	16	+	27260156	CADOES1	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2350824070296118	[1219]	[1401,1351,1348,1234]	4	hSpCas9	negative selection	6141097
66389403	66389426	16	-	27260156	CADOES1	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.4290003506939115	[1397]	[1000,898,967,995]	-6	hSpCas9	negative selection	6205373
66379358	66379381	16	-	27260156	CADOES1	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.1731360232965633	[3]	[0,1,3,9]	3	hSpCas9	negative selection	6205374
66389398	66389421	16	+	27260156	CADOES1	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.03872424652020934	[41]	[23,45,38,51]	0	hSpCas9	negative selection	6205375
66387020	66387043	16	+	27260156	EWS502	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.18147671176505903	[349]	[233,276,319,500]	-3	hSpCas9	negative selection	6262346
66387043	66387066	16	-	27260156	EWS502	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.26794642829861604	[1119]	[1042,979,941,962]	-5	hSpCas9	negative selection	6262347
66379349	66379372	16	+	27260156	EWS502	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.452512265287754	[1219]	[1535,1754,1600,2233]	7	hSpCas9	negative selection	6262348
66389403	66389426	16	-	27260156	EWS502	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.4654813163179925	[1397]	[932,1092,1000,1288]	-7	hSpCas9	negative selection	6326624
66379358	66379381	16	-	27260156	EWS502	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.081568668955347	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	6326625
66389398	66389421	16	+	27260156	EWS502	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.5746674757350689	[41]	[75,62,83,38]	8	hSpCas9	negative selection	6326626
66387020	66387043	16	+	27260156	EW8	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.3904388190226362	[349]	[362,489,233,421]	7	hSpCas9	negative selection	6383597
66387043	66387066	16	-	27260156	EW8	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.1499275590114859	[1119]	[1015,869,623,814]	-3	hSpCas9	negative selection	6383598
66379349	66379372	16	+	27260156	EW8	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.33665365025494953	[1219]	[1466,1331,1007,1248]	6	hSpCas9	negative selection	6383599
66389403	66389426	16	-	27260156	EW8	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.7122278471061376	[1397]	[910,672,515,717]	-8	hSpCas9	negative selection	6447875
66379358	66379381	16	-	27260156	EW8	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.0387849050346354	[3]	[0,0,2,0]	-9	hSpCas9	negative selection	6447876
66389398	66389421	16	+	27260156	EW8	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.4351971734128144	[41]	[12,10,13,62]	-7	hSpCas9	negative selection	6447877
66387020	66387043	16	+	27260156	CORL105	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.17329779298051806	[349]	[519,466,479,385]	3	hSpCas9	negative selection	6504848
66387043	66387066	16	-	27260156	CORL105	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.14498311858845492	[1119]	[1155,1117,1293,1191]	-3	hSpCas9	negative selection	6504849
66379349	66379372	16	+	27260156	CORL105	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.23334100223577336	[1219]	[1403,1541,2373,1497]	4	hSpCas9	negative selection	6504850
66389403	66389426	16	-	27260156	CORL105	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5851148661993706	[1397]	[1048,1121,1069,1116]	-8	hSpCas9	negative selection	6569126
66379358	66379381	16	-	27260156	CORL105	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.8915180434281016	[3]	[0,0,0,1]	-9	hSpCas9	negative selection	6569127
66389398	66389421	16	+	27260156	CORL105	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.2236885947350924	[41]	[90,58,57,22]	4	hSpCas9	negative selection	6569128
66387020	66387043	16	+	27260156	HS294T	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.04882567820660838	[349]	[162,136,123,131]	0	hSpCas9	negative selection	6626099
66387043	66387066	16	-	27260156	HS294T	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.23745301488546233	[1119]	[341,318,454,353]	-3	hSpCas9	negative selection	6626100
66379349	66379372	16	+	27260156	HS294T	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.31805138005269074	[1219]	[787,599,435,489]	4	hSpCas9	negative selection	6626101
66389403	66389426	16	-	27260156	HS294T	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.8767536374792154	[1397]	[273,267,309,333]	-8	hSpCas9	negative selection	6690377
66379358	66379381	16	-	27260156	HS294T	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.12159910987234213	[3]	[0,1,0,2]	1	hSpCas9	negative selection	6690378
66389398	66389421	16	+	27260156	HS294T	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.7467515093817987	[41]	[10,2,8,16]	-8	hSpCas9	negative selection	6690379
66387020	66387043	16	+	27260156	HCC44	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.2358791864511324	[349]	[500,352,851,247]	4	hSpCas9	negative selection	6747350
66387043	66387066	16	-	27260156	HCC44	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.042190976257502566	[1119]	[1118,1115,1161,1498]	0	hSpCas9	negative selection	6747351
66379349	66379372	16	+	27260156	HCC44	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.14510951960054985	[1219]	[1968,1366,1558,1272]	2	hSpCas9	negative selection	6747352
66389403	66389426	16	-	27260156	HCC44	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.8233753076931207	[1397]	[780,780,1102,941]	-8	hSpCas9	negative selection	6811628
66379358	66379381	16	-	27260156	HCC44	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.411778792332969	[3]	[3,0,0,0]	-9	hSpCas9	negative selection	6811629
66389398	66389421	16	+	27260156	HCC44	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.3511132727961779	[41]	[11,47,79,12]	-5	hSpCas9	negative selection	6811630
66387020	66387043	16	+	27260156	G402	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	1.0202857673751013	[349]	[460,1182,858,915]	9	hSpCas9	negative selection	6868601
66387043	66387066	16	-	27260156	G402	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.4236469899116194	[1119]	[1344,811,1341,626]	-5	hSpCas9	negative selection	6868602
66379349	66379372	16	+	27260156	G402	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.22143158794815743	[1219]	[1752,1977,1416,1800]	2	hSpCas9	negative selection	6868603
66389403	66389426	16	-	27260156	G402	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.24795950201698713	[1397]	[2164,1334,1589,781]	-3	hSpCas9	negative selection	6932879
66379358	66379381	16	-	27260156	G402	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-0.9313015444020998	[3]	[7,0,0,0]	-8	hSpCas9	negative selection	6932880
66389398	66389421	16	+	27260156	G402	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.3074087813786419	[41]	[133,16,17,9]	-4	hSpCas9	negative selection	6932881
66387020	66387043	16	+	27260156	L33	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.20856811191175012	[349]	[269,151,151,328]	-5	hSpCas9	negative selection	6989852
66387043	66387066	16	-	27260156	L33	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.009014846927364761	[1119]	[1128,445,738,1114]	0	hSpCas9	negative selection	6989853
66379349	66379372	16	+	27260156	L33	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.1322222151169934	[1219]	[1355,521,867,1336]	3	hSpCas9	negative selection	6989854
66389403	66389426	16	-	27260156	L33	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5070788733599847	[1397]	[902,442,528,1108]	-8	hSpCas9	negative selection	7054130
66379358	66379381	16	-	27260156	L33	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.0766717852629162	[3]	[0,0,1,0]	-9	hSpCas9	negative selection	7054131
66389398	66389421	16	+	27260156	L33	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.5229674732334093	[41]	[66,45,16,34]	9	hSpCas9	negative selection	7054132
66387020	66387043	16	+	27260156	K562	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.06353329126545226	[349]	[315,319,391,273]	0	hSpCas9	negative selection	7111103
66387043	66387066	16	-	27260156	K562	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.21396301121409822	[1119]	[944,810,760,905]	-3	hSpCas9	negative selection	7111104
66379349	66379372	16	+	27260156	K562	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.9444550078569078	[1219]	[1740,3328,1391,1919]	9	hSpCas9	negative selection	7111105
66389403	66389426	16	-	27260156	K562	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5843919781839517	[1397]	[881,858,769,803]	-6	hSpCas9	negative selection	7175381
66379358	66379381	16	-	27260156	K562	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.6049827290078831	[3]	[17,2,0,0]	7	hSpCas9	negative selection	7175382
66389398	66389421	16	+	27260156	K562	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.020128650152992034	[41]	[26,68,54,0]	0	hSpCas9	negative selection	7175383
66387020	66387043	16	+	27260156	HT29	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.02527609882309312	[349]	[472,426,502,339]	0	hSpCas9	negative selection	7232354
66387043	66387066	16	-	27260156	HT29	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.04717224946442311	[1119]	[1476,1275,1218,1299]	-1	hSpCas9	negative selection	7232355
66379349	66379372	16	+	27260156	HT29	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.3813974738930861	[1219]	[1676,2270,2051,1745]	7	hSpCas9	negative selection	7232356
66389403	66389426	16	-	27260156	HT29	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.43605872617285657	[1397]	[927,1580,1198,1303]	-7	hSpCas9	negative selection	7296632
66379358	66379381	16	-	27260156	HT29	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.2790189480051524	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7296633
66389398	66389421	16	+	27260156	HT29	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.047776779623314614	[41]	[31,58,68,49]	0	hSpCas9	negative selection	7296634
66387020	66387043	16	+	27260156	MHHES1	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.08758127121469456	[349]	[381,521,418,207]	-2	hSpCas9	negative selection	7353605
66387043	66387066	16	-	27260156	MHHES1	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.23093279081835716	[1119]	[1345,1088,970,934]	-4	hSpCas9	negative selection	7353606
66379349	66379372	16	+	27260156	MHHES1	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2264631929725054	[1219]	[1942,1401,1825,1312]	4	hSpCas9	negative selection	7353607
66389403	66389426	16	-	27260156	MHHES1	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.18307990197140156	[1397]	[1754,1581,1277,1044]	-3	hSpCas9	negative selection	7417883
66379358	66379381	16	-	27260156	MHHES1	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.1630968580950416	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7417884
66389398	66389421	16	+	27260156	MHHES1	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.6722561645896619	[41]	[9,53,28,25]	-8	hSpCas9	negative selection	7417885
66387020	66387043	16	+	27260156	MEWO	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.10225624264444427	[349]	[356,329,237]	-2	hSpCas9	negative selection	7474856
66387043	66387066	16	-	27260156	MEWO	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.05377221683166944	[1119]	[1055,1188,1010]	1	hSpCas9	negative selection	7474857
66379349	66379372	16	+	27260156	MEWO	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.3003834679545012	[1219]	[1539,1298,1403]	6	hSpCas9	negative selection	7474858
66389403	66389426	16	-	27260156	MEWO	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.44920272608532175	[1397]	[1043,832,1013]	-7	hSpCas9	negative selection	7539134
66379358	66379381	16	-	27260156	MEWO	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.9037906333919228	[3]	[0,0,0]	-9	hSpCas9	negative selection	7539135
66389398	66389421	16	+	27260156	MEWO	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.5137728568513644	[41]	[64,59,44]	9	hSpCas9	negative selection	7539136
66387020	66387043	16	+	27260156	LNCAPCLONEFGC	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.324771619967736	[349]	[338,336,516,417]	5	hSpCas9	negative selection	7596107
66387043	66387066	16	-	27260156	LNCAPCLONEFGC	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.30885121791501535	[1119]	[899,750,1037,621]	-5	hSpCas9	negative selection	7596108
66379349	66379372	16	+	27260156	LNCAPCLONEFGC	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2004237465990637	[1219]	[1241,1185,1386,1286]	3	hSpCas9	negative selection	7596109
66389403	66389426	16	-	27260156	LNCAPCLONEFGC	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5995413131655872	[1397]	[853,806,949,749]	-7	hSpCas9	negative selection	7660385
66379358	66379381	16	-	27260156	LNCAPCLONEFGC	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.2550663828566737	[3]	[2,0,0,0]	-9	hSpCas9	negative selection	7660386
66389398	66389421	16	+	27260156	LNCAPCLONEFGC	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.13657704403919935	[41]	[86,38,10,24]	2	hSpCas9	negative selection	7660387
66387020	66387043	16	+	27260156	PANC0327	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.18553786648791354	[349]	[223,186,494,194]	-3	hSpCas9	negative selection	7717358
66387043	66387066	16	-	27260156	PANC0327	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.004715211773740791	[1119]	[1083,1093,939,868]	0	hSpCas9	negative selection	7717359
66379349	66379372	16	+	27260156	PANC0327	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.3680625920600731	[1219]	[1765,1223,1356,1299]	5	hSpCas9	negative selection	7717360
66389403	66389426	16	-	27260156	PANC0327	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.21991129383550367	[1397]	[1456,1089,1054,691]	-3	hSpCas9	negative selection	7781636
66379358	66379381	16	-	27260156	PANC0327	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.8290241986648574	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	7781637
66389398	66389421	16	+	27260156	PANC0327	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-1.0122231479278998	[41]	[45,4,23,2]	-8	hSpCas9	negative selection	7781638
66387020	66387043	16	+	27260156	NCIH2009	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.1954110966713546	[349]	[587,526,569]	2	hSpCas9	negative selection	7838609
66387043	66387066	16	-	27260156	NCIH2009	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.07785546316801328	[1119]	[1795,1220,1494]	-1	hSpCas9	negative selection	7838610
66379349	66379372	16	+	27260156	NCIH2009	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.14671412464498168	[1219]	[2255,1760,1715]	2	hSpCas9	negative selection	7838611
66389403	66389426	16	-	27260156	NCIH2009	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.7071725382290363	[1397]	[1253,1169,1174]	-7	hSpCas9	negative selection	7902887
66379358	66379381	16	-	27260156	NCIH2009	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.120453841754019	[3]	[1,0,0]	-9	hSpCas9	negative selection	7902888
66389398	66389421	16	+	27260156	NCIH2009	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.2238965624419751	[41]	[106,42,11]	-3	hSpCas9	negative selection	7902889
66387020	66387043	16	+	27260156	NCIH1373	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.46384686554805815	[349]	[383,745,438,143]	4	hSpCas9	negative selection	7959860
66387043	66387066	16	-	27260156	NCIH1373	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.45103967253027677	[1119]	[911,1040,425,343]	-4	hSpCas9	negative selection	7959861
66379349	66379372	16	+	27260156	NCIH1373	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2601724842950164	[1219]	[2077,1458,1799,332]	2	hSpCas9	negative selection	7959862
66389403	66389426	16	-	27260156	NCIH1373	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5011477676276865	[1397]	[1077,975,1263,291]	-5	hSpCas9	negative selection	8024138
66379358	66379381	16	-	27260156	NCIH1373	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	0.7841700672284757	[3]	[28,0,0,0]	7	hSpCas9	negative selection	8024139
66389398	66389421	16	+	27260156	NCIH1373	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.5313116751231042	[41]	[162,65,4,13]	5	hSpCas9	negative selection	8024140
66387020	66387043	16	+	27260156	PATU8902	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.6528379156213988	[349]	[462,1265,316,1185]	7	hSpCas9	negative selection	8081111
66387043	66387066	16	-	27260156	PATU8902	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.9222898276171807	[1119]	[748,700,653,1280]	-7	hSpCas9	negative selection	8081112
66379349	66379372	16	+	27260156	PATU8902	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.11875951282925312	[1219]	[1893,1505,1677,2393]	1	hSpCas9	negative selection	8081113
66389403	66389426	16	-	27260156	PATU8902	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5826301860356803	[1397]	[1062,1916,417,2124]	-5	hSpCas9	negative selection	8145389
66379358	66379381	16	-	27260156	PATU8902	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.4750772158616208	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	8145390
66389398	66389421	16	+	27260156	PATU8902	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.5817701892018885	[41]	[72,80,127,52]	6	hSpCas9	negative selection	8145391
66387020	66387043	16	+	27260156	PANC1	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.12033153717241357	[349]	[227,376,333,197]	-2	hSpCas9	negative selection	8202362
66387043	66387066	16	-	27260156	PANC1	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.30490215045525737	[1119]	[788,865,726,742]	-5	hSpCas9	negative selection	8202363
66379349	66379372	16	+	27260156	PANC1	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.4901302858740326	[1219]	[1459,1649,1646,1190]	7	hSpCas9	negative selection	8202364
66389403	66389426	16	-	27260156	PANC1	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.7849079651166208	[1397]	[726,769,612,681]	-8	hSpCas9	negative selection	8266640
66379358	66379381	16	-	27260156	PANC1	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.1906950514100405	[3]	[0,0,2,0]	-9	hSpCas9	negative selection	8266641
66389398	66389421	16	+	27260156	PANC1	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.9740448965294659	[41]	[6,53,3,15]	-8	hSpCas9	negative selection	8266642
66387020	66387043	16	+	27260156	PANC0813	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.3449984184792545	[349]	[713,504,365,519]	5	hSpCas9	negative selection	8323613
66387043	66387066	16	-	27260156	PANC0813	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.10714521717057712	[1119]	[1216,1797,1247,1384]	1	hSpCas9	negative selection	8323614
66379349	66379372	16	+	27260156	PANC0813	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.19832455859580778	[1219]	[1599,1767,1631,1573]	3	hSpCas9	negative selection	8323615
66389403	66389426	16	-	27260156	PANC0813	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.538710871957722	[1397]	[1164,987,1125,1237]	-7	hSpCas9	negative selection	8387891
66379358	66379381	16	-	27260156	PANC0813	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.906596834867175	[3]	[0,1,0,0]	-9	hSpCas9	negative selection	8387892
66389398	66389421	16	+	27260156	PANC0813	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.9500277851437549	[41]	[46,33,197,97]	9	hSpCas9	negative selection	8387893
66387020	66387043	16	+	27260156	RDES	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.427555565737707	[349]	[479,503,619,567]	6	hSpCas9	negative selection	8444864
66387043	66387066	16	-	27260156	RDES	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.3657578761062459	[1119]	[853,942,1127,1098]	-6	hSpCas9	negative selection	8444865
66379349	66379372	16	+	27260156	RDES	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2579949877981331	[1219]	[1370,1627,1792,1990]	4	hSpCas9	negative selection	8444866
66389403	66389426	16	-	27260156	RDES	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5205926064466677	[1397]	[856,1042,1180,1492]	-7	hSpCas9	negative selection	8509142
66379358	66379381	16	-	27260156	RDES	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.8126748250091058	[3]	[1,0,0,0]	-9	hSpCas9	negative selection	8509143
66389398	66389421	16	+	27260156	RDES	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.2907879661339363	[41]	[28,52,107,52]	5	hSpCas9	negative selection	8509144
66387020	66387043	16	+	27260156	PC3	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.011405275744449939	[349]	[356,262,517,279]	0	hSpCas9	negative selection	8566115
66387043	66387066	16	-	27260156	PC3	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.011319866424276848	[1119]	[762,892,2043,1218]	0	hSpCas9	negative selection	8566116
66379349	66379372	16	+	27260156	PC3	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2794911204282997	[1219]	[1003,1560,2248,1434]	6	hSpCas9	negative selection	8566117
66389403	66389426	16	-	27260156	PC3	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.4747409006087062	[1397]	[631,1142,1366,1067]	-8	hSpCas9	negative selection	8630393
66379358	66379381	16	-	27260156	PC3	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.9424665231552556	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	8630394
66389398	66389421	16	+	27260156	PC3	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.481416652991673	[41]	[27,19,41,31]	-8	hSpCas9	negative selection	8630395
66387020	66387043	16	+	27260156	PATU8988T	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.23793252506083423	[349]	[204,405,295,247]	-4	hSpCas9	negative selection	8687366
66387043	66387066	16	-	27260156	PATU8988T	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.1783765605453067	[1119]	[672,877,1150,1126]	-3	hSpCas9	negative selection	8687367
66379349	66379372	16	+	27260156	PATU8988T	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.17133785752943043	[1219]	[936,1699,1213,1509]	3	hSpCas9	negative selection	8687368
66389403	66389426	16	-	27260156	PATU8988T	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.30183730826646493	[1397]	[865,892,971,1681]	-5	hSpCas9	negative selection	8751644
66379358	66379381	16	-	27260156	PATU8988T	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.9504748017735896	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	8751645
66389398	66389421	16	+	27260156	PATU8988T	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.3744530725053088	[41]	[26,56,49,78]	6	hSpCas9	negative selection	8751646
66387020	66387043	16	+	27260156	T47D	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.18495398821159753	[349]	[348,339,402,342]	-4	hSpCas9	negative selection	8808617
66387043	66387066	16	-	27260156	T47D	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.0995237840651928	[1119]	[1147,1177,1170,1382]	-2	hSpCas9	negative selection	8808618
66379349	66379372	16	+	27260156	T47D	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.28998743926549375	[1219]	[1737,1628,1890,1697]	6	hSpCas9	negative selection	8808619
66389403	66389426	16	-	27260156	T47D	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.500962985158478	[1397]	[1087,1246,1089,1170]	-8	hSpCas9	negative selection	8872895
66379358	66379381	16	-	27260156	T47D	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.4256143980297846	[3]	[3,0,0,0]	-9	hSpCas9	negative selection	8872896
66389398	66389421	16	+	27260156	T47D	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.020273895322852287	[41]	[43,47,70,28]	0	hSpCas9	negative selection	8872897
66387020	66387043	16	+	27260156	SU8686	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	0.37374816342552014	[349]	[478,388,448,488]	6	hSpCas9	negative selection	8929868
66387043	66387066	16	-	27260156	SU8686	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.11053307874129659	[1119]	[1208,955,1124,1587]	1	hSpCas9	negative selection	8929869
66379349	66379372	16	+	27260156	SU8686	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2607800017130344	[1219]	[1269,1253,1413,1978]	4	hSpCas9	negative selection	8929870
66389403	66389426	16	-	27260156	SU8686	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.4122908791868716	[1397]	[843,1029,1028,1324]	-6	hSpCas9	negative selection	8994146
66379358	66379381	16	-	27260156	SU8686	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-1.1172731437684407	[3]	[3,0,0,0]	-8	hSpCas9	negative selection	8994147
66389398	66389421	16	+	27260156	SU8686	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.5211772883269252	[41]	[39,81,23,96]	8	hSpCas9	negative selection	8994148
66387020	66387043	16	+	27260156	SKES1	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.20835194446097288	[349]	[382,278,326,232]	-4	hSpCas9	negative selection	9051119
66387043	66387066	16	-	27260156	SKES1	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.09512271012198803	[1119]	[1257,1023,1094,845]	-2	hSpCas9	negative selection	9051120
66379349	66379372	16	+	27260156	SKES1	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.2369548436796156	[1219]	[1448,1641,1387,1287]	5	hSpCas9	negative selection	9051121
66389403	66389426	16	-	27260156	SKES1	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.6395513553296874	[1397]	[1085,873,885,764]	-8	hSpCas9	negative selection	9115397
66379358	66379381	16	-	27260156	SKES1	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-0.6201950435733599	[3]	[0,7,0,0]	-8	hSpCas9	negative selection	9115398
66389398	66389421	16	+	27260156	SKES1	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.22821280766438745	[41]	[55,42,35,13]	-5	hSpCas9	negative selection	9115399
66387020	66387043	16	+	27260156	TOV112D	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.18293100141997015	[349]	[182,484,346,253]	-4	hSpCas9	negative selection	9172370
66387043	66387066	16	-	27260156	TOV112D	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.26585741354271886	[1119]	[945,1130,838,865]	-5	hSpCas9	negative selection	9172371
66379349	66379372	16	+	27260156	TOV112D	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.185527119338871	[1219]	[1592,1923,1245,953]	3	hSpCas9	negative selection	9172372
66389403	66389426	16	-	27260156	TOV112D	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.43182590406626886	[1397]	[1072,1501,1004,696]	-7	hSpCas9	negative selection	9236648
66379358	66379381	16	-	27260156	TOV112D	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.001586890435524	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	9236649
66389398	66389421	16	+	27260156	TOV112D	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	-0.21472045854758148	[41]	[56,9,28,43]	-4	hSpCas9	negative selection	9236650
66387020	66387043	16	+	27260156	TC71	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.1824805740164252	[349]	[276,330,341,375]	-5	hSpCas9	negative selection	9293621
66387043	66387066	16	-	27260156	TC71	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.3781701385514993	[1119]	[837,1012,989,848]	-8	hSpCas9	negative selection	9293622
66379349	66379372	16	+	27260156	TC71	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.27315580582542665	[1219]	[1327,1590,1631,1786]	6	hSpCas9	negative selection	9293623
66389403	66389426	16	-	27260156	TC71	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.4541678989152593	[1397]	[1132,984,993,1276]	-8	hSpCas9	negative selection	9357899
66379358	66379381	16	-	27260156	TC71	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	-2.1001916311946562	[3]	[0,0,0,0]	-9	hSpCas9	negative selection	9357900
66389398	66389421	16	+	27260156	TC71	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.3329946678732827	[41]	[30,74,65,54]	7	hSpCas9	negative selection	9357901
66387020	66387043	16	+	27260156	TC32	viability	TTCATGACGTGAACGACAACTGG	CDH5	ENSG00000179776	-0.06083212741700794	[349]	[345,216,375,348]	-1	hSpCas9	negative selection	9414872
66387043	66387066	16	-	27260156	TC32	viability	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.41593205376639153	[1119]	[745,565,1203,752]	-7	hSpCas9	negative selection	9414873
66379349	66379372	16	+	27260156	TC32	viability	CATGATGCTCCTCGCCACATCGG	CDH5	ENSG00000179776	0.09893723356949025	[1219]	[1133,898,1634,1386]	1	hSpCas9	negative selection	9414874
66389403	66389426	16	-	27260156	TC32	viability	TTCCACCACGATCTCATACCTGG	CDH5	ENSG00000179776	-0.5318708248473818	[1397]	[895,577,1220,1077]	-7	hSpCas9	negative selection	9479150
66379358	66379381	16	-	27260156	TC32	viability	GGCAGGCGCCCGATGTGGCGAGG	CDH5	ENSG00000179776	1.402498288347326	[3]	[2,22,0,5]	9	hSpCas9	negative selection	9479151
66389398	66389421	16	+	27260156	TC32	viability	GCAGGCCAGGTATGAGATCGTGG	CDH5	ENSG00000179776	0.7370369681600821	[41]	[52,113,20,43]	9	hSpCas9	negative selection	9479152
66379415	66379438	16	+	27869803	HPAFII	viability after 27 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	1.844336391697659	[226]	[373,473,NaN]	9	hSpCas9	negative selection	9557720
66387043	66387066	16	-	27869803	HPAFII	viability after 27 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.6194332765953012	[250]	[235,174,NaN]	5	hSpCas9	negative selection	9557721
66388384	66388407	16	-	27869803	HPAFII	viability after 27 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.428425107324818	[358]	[337,183,NaN]	3	hSpCas9	negative selection	9557722
66389419	66389442	16	+	27869803	HPAFII	viability after 27 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-4.853779259148956	[54]	[0,0,NaN]	-9	hSpCas9	negative selection	9557723
66390554	66390577	16	-	27869803	HPAFII	viability after 27 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.911130628311209	[432]	[618,268,NaN]	7	hSpCas9	negative selection	9557724
66392216	66392239	16	-	27869803	HPAFII	viability after 27 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.21734054093671423	[194]	[115,64,NaN]	-2	hSpCas9	negative selection	9557725
66379415	66379438	16	+	27869803	HPAFII	viability after 15 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.7706214074899935	[226]	[623,286,NaN]	8	hSpCas9	negative selection	9640169
66387043	66387066	16	-	27869803	HPAFII	viability after 15 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.3462393940651815	[250]	[382,105,NaN]	-4	hSpCas9	negative selection	9640170
66388384	66388407	16	-	27869803	HPAFII	viability after 15 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.3605462115559288	[358]	[696,369,NaN]	4	hSpCas9	negative selection	9640171
66389419	66389442	16	+	27869803	HPAFII	viability after 15 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-3.0441503031073696	[54]	[0,10,NaN]	-9	hSpCas9	negative selection	9640172
66390554	66390577	16	-	27869803	HPAFII	viability after 15 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.6176827201705412	[432]	[1231,391,NaN]	7	hSpCas9	negative selection	9640173
66392216	66392239	16	-	27869803	HPAFII	viability after 15 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.6568464879870022	[194]	[209,84,NaN]	-6	hSpCas9	negative selection	9640174
66379415	66379438	16	+	27869803	ASPC1	viability after 36 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.7835388869722705	[366]	[619,62,62]	7	hSpCas9	negative selection	9722618
66387043	66387066	16	-	27869803	ASPC1	viability after 36 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.09800910122696879	[569]	[274,381,32]	1	hSpCas9	negative selection	9722619
66388384	66388407	16	-	27869803	ASPC1	viability after 36 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.035691262877608376	[1045]	[76,435,484]	0	hSpCas9	negative selection	9722620
66389419	66389442	16	+	27869803	ASPC1	viability after 36 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	0.703362352619691	[69]	[0,37,67]	7	hSpCas9	negative selection	9722621
66390554	66390577	16	-	27869803	ASPC1	viability after 36 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.38419983124544577	[1385]	[565,911,447]	4	hSpCas9	negative selection	9722622
66392216	66392239	16	-	27869803	ASPC1	viability after 36 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.17389739696654305	[321]	[160,25,113]	-2	hSpCas9	negative selection	9722623
66379415	66379438	16	+	27869803	PATU8988S	viability after 35 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.6883456237733879	[311]	[197,206,NaN]	7	hSpCas9	negative selection	9805067
66387043	66387066	16	-	27869803	PATU8988S	viability after 35 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.6544855766839099	[640]	[168,158,NaN]	-6	hSpCas9	negative selection	9805068
66388384	66388407	16	-	27869803	PATU8988S	viability after 35 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.5019442861276551	[1001]	[272,296,NaN]	-5	hSpCas9	negative selection	9805069
66389419	66389442	16	+	27869803	PATU8988S	viability after 35 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	0.3702218705113114	[91]	[0,94,NaN]	4	hSpCas9	negative selection	9805070
66390554	66390577	16	-	27869803	PATU8988S	viability after 35 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.3590531767010907	[987]	[449,570,NaN]	4	hSpCas9	negative selection	9805071
66392216	66392239	16	-	27869803	PATU8988S	viability after 35 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.3067168494795992	[271]	[134,135,NaN]	3	hSpCas9	negative selection	9805072
66379415	66379438	16	+	27869803	PATU8988S	viability after 31 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	0.4167349008077953	[311]	[129,211,NaN]	5	hSpCas9	negative selection	9887516
66387043	66387066	16	-	27869803	PATU8988S	viability after 31 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	-0.38776827850873463	[640]	[164,233,NaN]	-4	hSpCas9	negative selection	9887517
66388384	66388407	16	-	27869803	PATU8988S	viability after 31 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.773625486146475	[1001]	[183,296,NaN]	-7	hSpCas9	negative selection	9887518
66389419	66389442	16	+	27869803	PATU8988S	viability after 31 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-0.5420285641925746	[91]	[0,55,NaN]	-5	hSpCas9	negative selection	9887519
66390554	66390577	16	-	27869803	PATU8988S	viability after 31 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.2531684033279187	[987]	[315,664,NaN]	3	hSpCas9	negative selection	9887520
66392216	66392239	16	-	27869803	PATU8988S	viability after 31 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.23670229922312624	[271]	[107,152,NaN]	3	hSpCas9	negative selection	9887521
66379415	66379438	16	+	27869803	HPAFII	viability after 35 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	2.4261262520641753	[226]	[452,802,NaN]	9	hSpCas9	negative selection	9969965
66387043	66387066	16	-	27869803	HPAFII	viability after 35 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	1.1777548700345601	[250]	[262,314,NaN]	7	hSpCas9	negative selection	9969966
66388384	66388407	16	-	27869803	HPAFII	viability after 35 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.4585950950147504	[358]	[340,146,NaN]	3	hSpCas9	negative selection	9969967
66389419	66389442	16	+	27869803	HPAFII	viability after 35 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-4.799271160527985	[54]	[0,0,NaN]	-9	hSpCas9	negative selection	9969968
66390554	66390577	16	-	27869803	HPAFII	viability after 35 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.6932899833078895	[432]	[424,274,NaN]	4	hSpCas9	negative selection	9969969
66392216	66392239	16	-	27869803	HPAFII	viability after 35 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	0.15056042895596763	[194]	[205,0,NaN]	0	hSpCas9	negative selection	9969970
66379415	66379438	16	+	27869803	HPAFII	viability after 31 days	AGGTGCTAACCCTGCCCAACGGG	CDH5	ENSG00000179776	2.021779693631799	[226]	[468,569,NaN]	9	hSpCas9	negative selection	10052414
66387043	66387066	16	-	27869803	HPAFII	viability after 31 days	AACAACCGATGCGTGAACACAGG	CDH5	ENSG00000179776	0.6041611445723832	[250]	[216,210,NaN]	4	hSpCas9	negative selection	10052415
66388384	66388407	16	-	27869803	HPAFII	viability after 31 days	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.20542086967959383	[358]	[294,163,NaN]	1	hSpCas9	negative selection	10052416
66389419	66389442	16	+	27869803	HPAFII	viability after 31 days	GGTGGAAGCGCGAGATGCCCAGG	CDH5	ENSG00000179776	-4.947988513849402	[54]	[0,0,NaN]	-9	hSpCas9	negative selection	10052417
66390554	66390577	16	-	27869803	HPAFII	viability after 31 days	TGATGCCCTCGTTGTGGGCGGGG	CDH5	ENSG00000179776	0.7924572010284586	[432]	[451,386,NaN]	6	hSpCas9	negative selection	10052418
66392216	66392239	16	-	27869803	HPAFII	viability after 31 days	GGGCTCTGTTTCCCGCGGGAGGG	CDH5	ENSG00000179776	-0.3822552124789356	[194]	[138,23,NaN]	-3	hSpCas9	negative selection	10052419
66389401	66389424	16	+	28162770	P31FUJ	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.3405583847702615	[263]	[244]	-3	hSpCas9	negative selection	10130429
66388426	66388449	16	-	28162770	P31FUJ	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.7673911826204155	[196]	[135]	-5	hSpCas9	negative selection	10130430
66389466	66389489	16	-	28162770	P31FUJ	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.31821296438344	[128]	[188]	3	hSpCas9	negative selection	10130431
66390445	66390468	16	-	28162770	P31FUJ	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.39149844425727826	[204]	[315]	4	hSpCas9	negative selection	10130432
66390548	66390571	16	+	28162770	P31FUJ	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.18980851456926612	[284]	[381]	2	hSpCas9	negative selection	10130433
66392361	66392384	16	+	28162770	P31FUJ	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-0.28776866363230713	[106]	[102]	-3	hSpCas9	negative selection	10130434
66379385	66379408	16	+	28162770	P31FUJ	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	-0.6951454184715791	[123]	[89]	-5	hSpCas9	negative selection	10130435
66379442	66379465	16	-	28162770	P31FUJ	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-1.030920436200405	[505]	[290]	-6	hSpCas9	negative selection	10130436
66388331	66388354	16	+	28162770	P31FUJ	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.834448036994817	[240]	[504]	8	hSpCas9	negative selection	10130437
66388384	66388407	16	-	28162770	P31FUJ	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.6426992534677356	[126]	[232]	7	hSpCas9	negative selection	10130438
66389401	66389424	16	+	28162770	TF1	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10299795
66388426	66388449	16	-	28162770	TF1	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10299796
66389466	66389489	16	-	28162770	TF1	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10299797
66390445	66390468	16	-	28162770	TF1	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	NaN	[NaN]	[257]	1	hSpCas9	negative selection	10299798
66390548	66390571	16	+	28162770	TF1	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	NaN	[NaN]	[459]	1	hSpCas9	negative selection	10299799
66392361	66392384	16	+	28162770	TF1	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10299800
66379385	66379408	16	+	28162770	TF1	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10299801
66379442	66379465	16	-	28162770	TF1	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10299802
66388331	66388354	16	+	28162770	TF1	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10299803
66388384	66388407	16	-	28162770	TF1	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10299804
66389401	66389424	16	+	28162770	SKM1	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-1.2005133212757353	[51]	[39]	-7	hSpCas9	negative selection	10469161
66388426	66388449	16	-	28162770	SKM1	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.8047809783937778	[33]	[104]	7	hSpCas9	negative selection	10469162
66389466	66389489	16	-	28162770	SKM1	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.16405911102012072	[51]	[102]	1	hSpCas9	negative selection	10469163
66390445	66390468	16	-	28162770	SKM1	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.29946181446366177	[73]	[160]	3	hSpCas9	negative selection	10469164
66390548	66390571	16	+	28162770	SKM1	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.4498029174395205	[81]	[197]	4	hSpCas9	negative selection	10469165
66392361	66392384	16	+	28162770	SKM1	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-0.27885937299547636	[34]	[50]	-2	hSpCas9	negative selection	10469166
66379385	66379408	16	+	28162770	SKM1	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.47078005120584043	[19]	[48]	4	hSpCas9	negative selection	10469167
66379442	66379465	16	-	28162770	SKM1	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	0.08223931917256366	[108]	[203]	0	hSpCas9	negative selection	10469168
66388331	66388354	16	+	28162770	SKM1	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.8395820843020633	[54]	[173]	7	hSpCas9	negative selection	10469169
66388384	66388407	16	-	28162770	SKM1	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.6597302691231285	[41]	[46]	-5	hSpCas9	negative selection	10469170
66389401	66389424	16	+	28162770	SKM1	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-1.2005133212757353	[51]	[39]	-7	hSpCas9	negative selection	10638527
66388426	66388449	16	-	28162770	SKM1	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.8047809783937778	[33]	[104]	7	hSpCas9	negative selection	10638528
66389466	66389489	16	-	28162770	SKM1	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.16405911102012072	[51]	[102]	1	hSpCas9	negative selection	10638529
66390445	66390468	16	-	28162770	SKM1	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.29946181446366177	[73]	[160]	3	hSpCas9	negative selection	10638530
66390548	66390571	16	+	28162770	SKM1	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.4498029174395205	[81]	[197]	4	hSpCas9	negative selection	10638531
66392361	66392384	16	+	28162770	SKM1	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-0.27885937299547636	[34]	[50]	-2	hSpCas9	negative selection	10638532
66379385	66379408	16	+	28162770	SKM1	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.47078005120584043	[19]	[48]	4	hSpCas9	negative selection	10638533
66379442	66379465	16	-	28162770	SKM1	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	0.08223931917256366	[108]	[203]	0	hSpCas9	negative selection	10638534
66388331	66388354	16	+	28162770	SKM1	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.8395820843020633	[54]	[173]	7	hSpCas9	negative selection	10638535
66388384	66388407	16	-	28162770	SKM1	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.6597302691231285	[41]	[46]	-5	hSpCas9	negative selection	10638536
66389401	66389424	16	+	28162770	PL21	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-1.212799418905526	[228]	[42]	-7	hSpCas9	negative selection	10807893
66388426	66388449	16	-	28162770	PL21	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.5031428534205974	[126]	[38]	-4	hSpCas9	negative selection	10807894
66389466	66389489	16	-	28162770	PL21	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.7437613198295768	[117]	[85]	6	hSpCas9	negative selection	10807895
66390445	66390468	16	-	28162770	PL21	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	-0.14204731938184212	[250]	[98]	-1	hSpCas9	negative selection	10807896
66390548	66390571	16	+	28162770	PL21	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	-0.29512008328360395	[264]	[93]	-2	hSpCas9	negative selection	10807897
66392361	66392384	16	+	28162770	PL21	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-2.769486736467161	[93]	[5]	-9	hSpCas9	negative selection	10807898
66379385	66379408	16	+	28162770	PL21	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	-2.3323554663377006	[80]	[6]	-8	hSpCas9	negative selection	10807899
66379442	66379465	16	-	28162770	PL21	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-0.15854703040815998	[317]	[123]	-1	hSpCas9	negative selection	10807900
66388331	66388354	16	+	28162770	PL21	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	1.0348911002564811	[230]	[205]	8	hSpCas9	negative selection	10807901
66388384	66388407	16	-	28162770	PL21	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-1.7784867347181128	[133]	[16]	-8	hSpCas9	negative selection	10807902
66389401	66389424	16	+	28162770	P31FUJ	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.3405583847702615	[263]	[244]	-3	hSpCas9	negative selection	10977259
66388426	66388449	16	-	28162770	P31FUJ	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.7673911826204155	[196]	[135]	-5	hSpCas9	negative selection	10977260
66389466	66389489	16	-	28162770	P31FUJ	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.31821296438344	[128]	[188]	3	hSpCas9	negative selection	10977261
66390445	66390468	16	-	28162770	P31FUJ	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.39149844425727826	[204]	[315]	4	hSpCas9	negative selection	10977262
66390548	66390571	16	+	28162770	P31FUJ	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.18980851456926612	[284]	[381]	2	hSpCas9	negative selection	10977263
66392361	66392384	16	+	28162770	P31FUJ	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-0.28776866363230713	[106]	[102]	-3	hSpCas9	negative selection	10977264
66379385	66379408	16	+	28162770	P31FUJ	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	-0.6951454184715791	[123]	[89]	-5	hSpCas9	negative selection	10977265
66379442	66379465	16	-	28162770	P31FUJ	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-1.030920436200405	[505]	[290]	-6	hSpCas9	negative selection	10977266
66388331	66388354	16	+	28162770	P31FUJ	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.834448036994817	[240]	[504]	8	hSpCas9	negative selection	10977267
66388384	66388407	16	-	28162770	P31FUJ	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.6426992534677356	[126]	[232]	7	hSpCas9	negative selection	10977268
66389401	66389424	16	+	28162770	OCIAML5	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.7347096202258382	[117]	[127]	-5	hSpCas9	negative selection	11146625
66388426	66388449	16	-	28162770	OCIAML5	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.7067661980325057	[129]	[382]	6	hSpCas9	negative selection	11146626
66389466	66389489	16	-	28162770	OCIAML5	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	-0.8229202252044805	[48]	[49]	-5	hSpCas9	negative selection	11146627
66390445	66390468	16	-	28162770	OCIAML5	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.8334228058111237	[96]	[311]	7	hSpCas9	negative selection	11146628
66390548	66390571	16	+	28162770	OCIAML5	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.9006820205431368	[99]	[336]	7	hSpCas9	negative selection	11146629
66392361	66392384	16	+	28162770	OCIAML5	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-2.4236085558228315	[106]	[35]	-8	hSpCas9	negative selection	11146630
66379385	66379408	16	+	28162770	OCIAML5	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.6981305116964824	[27]	[81]	6	hSpCas9	negative selection	11146631
66379442	66379465	16	-	28162770	OCIAML5	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-2.4512429308048542	[305]	[100]	-8	hSpCas9	negative selection	11146632
66388331	66388354	16	+	28162770	OCIAML5	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.5581410108106527	[186]	[496]	5	hSpCas9	negative selection	11146633
66388384	66388407	16	-	28162770	OCIAML5	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.5338245827553304	[74]	[195]	4	hSpCas9	negative selection	11146634
66389401	66389424	16	+	28162770	EOL1	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.8978093138263162	[434]	[122]	-6	hSpCas9	negative selection	11315991
66388426	66388449	16	-	28162770	EOL1	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.10615457806048223	[163]	[92]	1	hSpCas9	negative selection	11315992
66389466	66389489	16	-	28162770	EOL1	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.6654605502534036	[218]	[182]	6	hSpCas9	negative selection	11315993
66390445	66390468	16	-	28162770	EOL1	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.5247151439030231	[408]	[309]	5	hSpCas9	negative selection	11315994
66390548	66390571	16	+	28162770	EOL1	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.9245477715705346	[512]	[512]	7	hSpCas9	negative selection	11315995
66392361	66392384	16	+	28162770	EOL1	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	-1.0260642014673018	[200]	[51]	-6	hSpCas9	negative selection	11315996
66379385	66379408	16	+	28162770	EOL1	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	-2.611505128669675	[115]	[9]	-9	hSpCas9	negative selection	11315997
66379442	66379465	16	-	28162770	EOL1	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-0.8043241405493351	[473]	[142]	-5	hSpCas9	negative selection	11315998
66388331	66388354	16	+	28162770	EOL1	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.3784866216657702	[310]	[212]	3	hSpCas9	negative selection	11315999
66388384	66388407	16	-	28162770	EOL1	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.10219068617368376	[144]	[81]	0	hSpCas9	negative selection	11316000
66389401	66389424	16	+	28162770	MOLM13	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	0.5001297185447866	[353]	[361]	4	hSpCas9	negative selection	11485357
66388426	66388449	16	-	28162770	MOLM13	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-2.164378833954934	[340]	[54]	-7	hSpCas9	negative selection	11485358
66389466	66389489	16	-	28162770	MOLM13	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.008457762907281396	[142]	[103]	0	hSpCas9	negative selection	11485359
66390445	66390468	16	-	28162770	MOLM13	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.20329446172316806	[369]	[307]	1	hSpCas9	negative selection	11485360
66390548	66390571	16	+	28162770	MOLM13	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.13990861653495812	[417]	[332]	1	hSpCas9	negative selection	11485361
66392361	66392384	16	+	28162770	MOLM13	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.2765907293096993	[152]	[133]	2	hSpCas9	negative selection	11485362
66379385	66379408	16	+	28162770	MOLM13	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.577118451299337	[88]	[95]	4	hSpCas9	negative selection	11485363
66379442	66379465	16	-	28162770	MOLM13	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-2.409854868404423	[440]	[59]	-8	hSpCas9	negative selection	11485364
66388331	66388354	16	+	28162770	MOLM13	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	-0.09206911304668297	[428]	[290]	0	hSpCas9	negative selection	11485365
66388384	66388407	16	-	28162770	MOLM13	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.07903581406938975	[181]	[138]	0	hSpCas9	negative selection	11485366
66389401	66389424	16	+	28162770	HEL	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.3759977305812288	[309]	[152]	-3	hSpCas9	negative selection	11654723
66388426	66388449	16	-	28162770	HEL	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.1173103752788904	[209]	[123]	-1	hSpCas9	negative selection	11654724
66389466	66389489	16	-	28162770	HEL	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	-0.0469210473874927	[149]	[92]	0	hSpCas9	negative selection	11654725
66390445	66390468	16	-	28162770	HEL	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.36480856611299173	[330]	[272]	3	hSpCas9	negative selection	11654726
66390548	66390571	16	+	28162770	HEL	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.7287786630670484	[357]	[379]	6	hSpCas9	negative selection	11654727
66392361	66392384	16	+	28162770	HEL	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.1573120048301151	[97]	[69]	1	hSpCas9	negative selection	11654728
66379385	66379408	16	+	28162770	HEL	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	-0.5519085988531867	[102]	[44]	-4	hSpCas9	negative selection	11654729
66379442	66379465	16	-	28162770	HEL	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-1.9227011104559804	[366]	[61]	-7	hSpCas9	negative selection	11654730
66388331	66388354	16	+	28162770	HEL	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.0417589339418325	[316]	[208]	0	hSpCas9	negative selection	11654731
66388384	66388407	16	-	28162770	HEL	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	1.0404983398473653	[125]	[165]	8	hSpCas9	negative selection	11654732
66389401	66389424	16	+	28162770	MV411	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-0.7696359625761663	[254]	[125]	-5	hSpCas9	negative selection	11824089
66388426	66388449	16	-	28162770	MV411	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.13626674169127695	[166]	[127]	-1	hSpCas9	negative selection	11824090
66389466	66389489	16	-	28162770	MV411	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.6972404682222959	[122]	[167]	6	hSpCas9	negative selection	11824091
66390445	66390468	16	-	28162770	MV411	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	0.9620353319205269	[194]	[319]	8	hSpCas9	negative selection	11824092
66390548	66390571	16	+	28162770	MV411	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.6812585257410348	[247]	[334]	6	hSpCas9	negative selection	11824093
66392361	66392384	16	+	28162770	MV411	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.5170446105400553	[72]	[87]	4	hSpCas9	negative selection	11824094
66379385	66379408	16	+	28162770	MV411	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.7104095271253212	[73]	[101]	6	hSpCas9	negative selection	11824095
66379442	66379465	16	-	28162770	MV411	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-1.0813989134467648	[313]	[124]	-6	hSpCas9	negative selection	11824096
66388331	66388354	16	+	28162770	MV411	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.4504646472522921	[224]	[258]	4	hSpCas9	negative selection	11824097
66388384	66388407	16	-	28162770	MV411	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.5727414116324122	[112]	[63]	-4	hSpCas9	negative selection	11824098
66389401	66389424	16	+	28162770	MONOMAC1	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-1.0792003567656956	[187]	[101]	-7	hSpCas9	negative selection	11993455
66388426	66388449	16	-	28162770	MONOMAC1	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.16227142889887702	[81]	[83]	-1	hSpCas9	negative selection	11993456
66389466	66389489	16	-	28162770	MONOMAC1	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	-0.03265002915867132	[57]	[64]	0	hSpCas9	negative selection	11993457
66390445	66390468	16	-	28162770	MONOMAC1	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	-0.5485092175609314	[184]	[144]	-5	hSpCas9	negative selection	11993458
66390548	66390571	16	+	28162770	MONOMAC1	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.14961367723904	[161]	[205]	1	hSpCas9	negative selection	11993459
66392361	66392384	16	+	28162770	MONOMAC1	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.5399287471066525	[47]	[79]	5	hSpCas9	negative selection	11993460
66379385	66379408	16	+	28162770	MONOMAC1	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.2180006522192901	[38]	[51]	2	hSpCas9	negative selection	11993461
66379442	66379465	16	-	28162770	MONOMAC1	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-0.7721515618243626	[218]	[146]	-6	hSpCas9	negative selection	11993462
66388331	66388354	16	+	28162770	MONOMAC1	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	-0.009103896466478564	[114]	[130]	0	hSpCas9	negative selection	11993463
66388384	66388407	16	-	28162770	MONOMAC1	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	1.7168065091907316	[68]	[259]	9	hSpCas9	negative selection	11993464
66389401	66389424	16	+	28162770	OCIAML2	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-1.3865655604536868	[49]	[105]	-7	hSpCas9	negative selection	12162821
66388426	66388449	16	-	28162770	OCIAML2	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	0.8147723936200871	[19]	[194]	7	hSpCas9	negative selection	12162822
66389466	66389489	16	-	28162770	OCIAML2	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.14828000740233227	[13]	[85]	1	hSpCas9	negative selection	12162823
66390445	66390468	16	-	28162770	OCIAML2	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	-0.5220289777488054	[49]	[192]	-4	hSpCas9	negative selection	12162824
66390548	66390571	16	+	28162770	OCIAML2	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	0.6262317140104275	[53]	[461]	6	hSpCas9	negative selection	12162825
66392361	66392384	16	+	28162770	OCIAML2	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.6491094190319343	[12]	[112]	6	hSpCas9	negative selection	12162826
66379385	66379408	16	+	28162770	OCIAML2	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.37067242873878037	[11]	[85]	3	hSpCas9	negative selection	12162827
66379442	66379465	16	-	28162770	OCIAML2	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-0.4966250337751058	[55]	[219]	-4	hSpCas9	negative selection	12162828
66388331	66388354	16	+	28162770	OCIAML2	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.6295068460432888	[39]	[342]	6	hSpCas9	negative selection	12162829
66388384	66388407	16	-	28162770	OCIAML2	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	0.4553695933140621	[14]	[113]	4	hSpCas9	negative selection	12162830
66389401	66389424	16	+	28162770	OCIAML3	viability	GGCCAGGTATGAGATCGTGGTGG	CDH5	ENSG00000179776	-1.1388130145733366	[61]	[84]	-7	hSpCas9	negative selection	12332187
66388426	66388449	16	-	28162770	OCIAML3	viability	ACACAGACCAGAATTATCGATGG	CDH5	ENSG00000179776	-0.021756191352560794	[37]	[112]	0	hSpCas9	negative selection	12332188
66389466	66389489	16	-	28162770	OCIAML3	viability	TTGCAGAGTGACCAGCACGGTGG	CDH5	ENSG00000179776	0.11786697287921266	[28]	[94]	1	hSpCas9	negative selection	12332189
66390445	66390468	16	-	28162770	OCIAML3	viability	AACAAACAGAGAGCCCACAGAGG	CDH5	ENSG00000179776	-0.37499785838236743	[60]	[141]	-3	hSpCas9	negative selection	12332190
66390548	66390571	16	+	28162770	OCIAML3	viability	GACAAACCCCGCCCACAACGAGG	CDH5	ENSG00000179776	-0.6324817881387987	[75]	[147]	-5	hSpCas9	negative selection	12332191
66392361	66392384	16	+	28162770	OCIAML3	viability	GATGCGGCTAGGCATAGCATTGG	CDH5	ENSG00000179776	0.33199177823205994	[24]	[94]	3	hSpCas9	negative selection	12332192
66379385	66379408	16	+	28162770	OCIAML3	viability	CCTGCTGGCAGTGGCAGCAGTGG	CDH5	ENSG00000179776	0.6337982771986492	[18]	[88]	6	hSpCas9	negative selection	12332193
66379442	66379465	16	-	28162770	OCIAML3	viability	GGTGGGTGGGCAGCAGGCTGTGG	CDH5	ENSG00000179776	-1.0634929236253834	[116]	[168]	-6	hSpCas9	negative selection	12332194
66388331	66388354	16	+	28162770	OCIAML3	viability	AGTCATCTCTGTGACAGCAGTGG	CDH5	ENSG00000179776	0.7279204545631992	[69]	[349]	6	hSpCas9	negative selection	12332195
66388384	66388407	16	-	28162770	OCIAML3	viability	CAGGATTTGGTACATGACAGAGG	CDH5	ENSG00000179776	-0.07743211458325694	[35]	[102]	0	hSpCas9	negative selection	12332196