Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8558
• Symbol:CDK10
• Description:cyclin dependent kinase 10

DataSource: http://genomecrispr.dkfz.de/#!/results/CDK10

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
89691498	89691521	16	+	26472758	Jiyoye	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	0.4637589098722408	[49]	[51]	3	hSpCas9	negative selection	28657
89691486	89691509	16	+	26472758	Jiyoye	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	-0.27988530683401897	[160]	[99]	-2	hSpCas9	negative selection	28658
89694713	89694736	16	-	26472758	Jiyoye	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	28659
89690593	89690616	16	+	26472758	Jiyoye	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.3374896357015187	[614]	[585]	2	hSpCas9	negative selection	28660
89692477	89692500	16	+	26472758	Jiyoye	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	1.5520490108928184	[70]	[156]	8	hSpCas9	negative selection	28661
89691449	89691472	16	-	26472758	Jiyoye	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.5566562801810953	[228]	[253]	4	hSpCas9	negative selection	28662
89691534	89691557	16	-	26472758	Jiyoye	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.28759376575320084	[87]	[80]	2	hSpCas9	negative selection	28663
89691860	89691883	16	+	26472758	Jiyoye	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.7021720146824877	[547]	[253]	-5	hSpCas9	negative selection	28664
89694202	89694225	16	-	26472758	Jiyoye	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	-0.9284276502785656	[52]	[20]	-6	hSpCas9	negative selection	28665
89690603	89690626	16	+	26472758	Jiyoye	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-0.418795218719078	[38]	[21]	-3	hSpCas9	negative selection	28666
89693610	89693633	16	+	26472758	Jiyoye	viability	GGACAGCCTCCAGGACACAGCAG	CDK10	ENSG00000185324	-1.0382357668164892	[255]	[93]	-6	hSpCas9	negative selection	150377
89691498	89691521	16	+	26472758	KBM7	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	0.6016893600324948	[214,144]	[201,58]	6	hSpCas9	negative selection	219775
89691486	89691509	16	+	26472758	KBM7	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.08399755667171686	[326,497]	[230,192]	0	hSpCas9	negative selection	219776
89694713	89694736	16	-	26472758	KBM7	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	0.25173859695934997	[9,6]	[0,7]	2	hSpCas9	negative selection	219777
89690593	89690616	16	+	26472758	KBM7	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.3133474440973387	[2441,2222]	[1497,1241]	3	hSpCas9	negative selection	219778
89692477	89692500	16	+	26472758	KBM7	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.9300882291527204	[346,366]	[92,84]	-6	hSpCas9	negative selection	219779
89691449	89691472	16	-	26472758	KBM7	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.2052840707801481	[714,873]	[612,279]	2	hSpCas9	negative selection	219780
89691534	89691557	16	-	26472758	KBM7	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.2807082609347925	[460,462]	[175,344]	3	hSpCas9	negative selection	219781
89691860	89691883	16	+	26472758	KBM7	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.5111689599047267	[1601,1278]	[441,498]	-4	hSpCas9	negative selection	219782
89694202	89694225	16	-	26472758	KBM7	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.21734383726722983	[157,110]	[42,98]	2	hSpCas9	negative selection	219783
89690603	89690626	16	+	26472758	KBM7	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-4.293310357293903	[330,380]	[5,10]	-9	hSpCas9	negative selection	219784
89693610	89693633	16	+	26472758	KBM7	viability	GGACAGCCTCCAGGACACAGCAG	CDK10	ENSG00000185324	-0.1787319631942691	[722,590]	[281,261]	-2	hSpCas9	negative selection	341495
89691498	89691521	16	+	26472758	Raji	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	1.0042900424094958	[57]	[26]	8	hSpCas9	negative selection	410893
89691486	89691509	16	+	26472758	Raji	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.7693357751229603	[224]	[88]	7	hSpCas9	negative selection	410894
89694713	89694736	16	-	26472758	Raji	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-0.8926164646264008	[7]	[0]	-6	hSpCas9	negative selection	410895
89690593	89690616	16	+	26472758	Raji	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.014274130982117939	[1087]	[254]	0	hSpCas9	negative selection	410896
89692477	89692500	16	+	26472758	Raji	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.5224210346524433	[191]	[63]	5	hSpCas9	negative selection	410897
89691449	89691472	16	-	26472758	Raji	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.8210793502169582	[299]	[122]	7	hSpCas9	negative selection	410898
89691534	89691557	16	-	26472758	Raji	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.3830179779870269	[227]	[68]	3	hSpCas9	negative selection	410899
89691860	89691883	16	+	26472758	Raji	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.17913922338256416	[804]	[164]	-1	hSpCas9	negative selection	410900
89694202	89694225	16	-	26472758	Raji	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.8249838046728746	[89]	[36]	7	hSpCas9	negative selection	410901
89690603	89690626	16	+	26472758	Raji	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-2.98007930587674	[135]	[3]	-9	hSpCas9	negative selection	410902
89693610	89693633	16	+	26472758	Raji	viability	GGACAGCCTCCAGGACACAGCAG	CDK10	ENSG00000185324	0.5847053129067861	[203]	[70]	5	hSpCas9	negative selection	532613
89691498	89691521	16	+	26472758	K562	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-0.6789599907306405	[109]	[57]	-4	hSpCas9	negative selection	602011
89691486	89691509	16	+	26472758	K562	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.9217452465362628	[241]	[386]	7	hSpCas9	negative selection	602012
89694713	89694736	16	-	26472758	K562	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-3.2150128909708497	[10]	[0]	-8	hSpCas9	negative selection	602013
89690593	89690616	16	+	26472758	K562	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	-0.20218885061326697	[2001]	[1468]	-1	hSpCas9	negative selection	602014
89692477	89692500	16	+	26472758	K562	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.7254133085214279	[325]	[454]	6	hSpCas9	negative selection	602015
89691449	89691472	16	-	26472758	K562	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.8745668912915904	[680]	[1053]	7	hSpCas9	negative selection	602016
89691534	89691557	16	-	26472758	K562	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-2.7243303383491133	[273]	[34]	-8	hSpCas9	negative selection	602017
89691860	89691883	16	+	26472758	K562	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.242303739501867	[1113]	[794]	-2	hSpCas9	negative selection	602018
89694202	89694225	16	-	26472758	K562	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	-0.47425571764227004	[208]	[126]	-3	hSpCas9	negative selection	602019
89690603	89690626	16	+	26472758	K562	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-0.2655817153734872	[224]	[157]	-2	hSpCas9	negative selection	602020
89693610	89693633	16	+	26472758	K562	viability	GGACAGCCTCCAGGACACAGCAG	CDK10	ENSG00000185324	0.3762951212595796	[396]	[434]	3	hSpCas9	negative selection	723731
89686775	89686798	16	+	26627737	DLD1	viability	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.990183090345242	[799]	[129,112,132]	-7	hSpCas9	negative selection	795968
89687448	89687471	16	+	26627737	DLD1	viability	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	0.45687830268360763	[477]	[226,110,263]	4	hSpCas9	negative selection	795969
89689285	89689308	16	+	26627737	DLD1	viability	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-1.3942556939765567	[816]	[116,78,94]	-8	hSpCas9	negative selection	795970
89690542	89690565	16	+	26627737	DLD1	viability	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.1567946827072647	[234]	[94,50,52]	-2	hSpCas9	negative selection	795971
89691871	89691894	16	-	26627737	DLD1	viability	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-1.1733859135638924	[740]	[145,85,78]	-8	hSpCas9	negative selection	795972
89692475	89692498	16	-	26627737	DLD1	viability	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	0.20101022714869016	[328]	[265,57,39]	2	hSpCas9	negative selection	795973
89686775	89686798	16	+	26627737	GBM cells	viability after 5 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.3499066717284074	[403]	[154,184]	-5	hSpCas9	negative selection	878283
89687448	89687471	16	+	26627737	GBM cells	viability after 5 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.01962202448541806	[240]	[155,98]	0	hSpCas9	negative selection	878284
89689285	89689308	16	+	26627737	GBM cells	viability after 5 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	0.1599319351209747	[357]	[207,220]	2	hSpCas9	negative selection	878285
89690542	89690565	16	+	26627737	GBM cells	viability after 5 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.047893185948721106	[212]	[121,98]	0	hSpCas9	negative selection	878286
89691871	89691894	16	-	26627737	GBM cells	viability after 5 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.1693657522819625	[387]	[237,229]	2	hSpCas9	negative selection	878287
89692475	89692498	16	-	26627737	GBM cells	viability after 5 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.5982422448666634	[246]	[54,119]	-7	hSpCas9	negative selection	878288
89686775	89686798	16	+	26627737	GBM cells	viability after 13 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.1431131620303897	[403]	[160,228]	-2	hSpCas9	negative selection	960598
89687448	89687471	16	+	26627737	GBM cells	viability after 13 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	0.0524584474462229	[240]	[171,105]	0	hSpCas9	negative selection	960599
89689285	89689308	16	+	26627737	GBM cells	viability after 13 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	0.3390327588003752	[357]	[264,229]	4	hSpCas9	negative selection	960600
89690542	89690565	16	+	26627737	GBM cells	viability after 13 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	0.1303032174928871	[212]	[147,108]	1	hSpCas9	negative selection	960601
89691871	89691894	16	-	26627737	GBM cells	viability after 13 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.1220887527629525	[387]	[243,216]	1	hSpCas9	negative selection	960602
89692475	89692498	16	-	26627737	GBM cells	viability after 13 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-1.00302766051203	[246]	[78,56]	-8	hSpCas9	negative selection	960603
89686775	89686798	16	+	26627737	GBM cells	viability after 21 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.026582901508332313	[403]	[215,214]	0	hSpCas9	negative selection	1042913
89687448	89687471	16	+	26627737	GBM cells	viability after 21 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	0.28957258843577255	[240]	[170,149]	3	hSpCas9	negative selection	1042914
89689285	89689308	16	+	26627737	GBM cells	viability after 21 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	0.7660391011474998	[357]	[359,303]	7	hSpCas9	negative selection	1042915
89690542	89690565	16	+	26627737	GBM cells	viability after 21 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	0.18163622419409978	[212]	[148,114]	2	hSpCas9	negative selection	1042916
89691871	89691894	16	-	26627737	GBM cells	viability after 21 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.07398108588674734	[387]	[205,194]	0	hSpCas9	negative selection	1042917
89692475	89692498	16	-	26627737	GBM cells	viability after 21 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-1.9443573913305965	[246]	[37,31]	-8	hSpCas9	negative selection	1042918
89686775	89686798	16	+	26627737	RPE1	viability after 9 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.9655403010895541	[518]	[277,367]	6	hSpCas9	negative selection	1125228
89687448	89687471	16	+	26627737	RPE1	viability after 9 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	2.042115760179625	[230]	[313,276]	9	hSpCas9	negative selection	1125229
89689285	89689308	16	+	26627737	RPE1	viability after 9 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.7935724911185585	[2000]	[346,379]	-5	hSpCas9	negative selection	1125230
89690542	89690565	16	+	26627737	RPE1	viability after 9 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-1.333699667227494	[993]	[74,185]	-7	hSpCas9	negative selection	1125231
89691871	89691894	16	-	26627737	RPE1	viability after 9 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-1.2451649916266214	[1577]	[255,146]	-7	hSpCas9	negative selection	1125232
89692475	89692498	16	-	26627737	RPE1	viability after 9 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	1.6335179185665067	[236]	[179,294]	8	hSpCas9	negative selection	1125233
89686775	89686798	16	+	26627737	RPE1	viability after 12 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	1.1256680056875399	[518]	[312,294]	6	hSpCas9	negative selection	1207543
89687448	89687471	16	+	26627737	RPE1	viability after 12 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	1.922632287925831	[230]	[261,206]	8	hSpCas9	negative selection	1207544
89689285	89689308	16	+	26627737	RPE1	viability after 12 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.4568413397464408	[2000]	[431,348]	-3	hSpCas9	negative selection	1207545
89690542	89690565	16	+	26627737	RPE1	viability after 12 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-1.4450195048768582	[993]	[117,76]	-7	hSpCas9	negative selection	1207546
89691871	89691894	16	-	26627737	RPE1	viability after 12 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.8721006675529203	[1577]	[184,280]	-6	hSpCas9	negative selection	1207547
89692475	89692498	16	-	26627737	RPE1	viability after 12 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	1.5959757298171928	[236]	[89,300]	8	hSpCas9	negative selection	1207548
89686775	89686798	16	+	26627737	RPE1	viability after 15 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	1.7082120944937136	[518]	[635,328]	8	hSpCas9	negative selection	1289858
89687448	89687471	16	+	26627737	RPE1	viability after 15 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	3.4729396081986526	[230]	[1284,185]	9	hSpCas9	negative selection	1289859
89689285	89689308	16	+	26627737	RPE1	viability after 15 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.5282659471783541	[2000]	[533,255]	-3	hSpCas9	negative selection	1289860
89690542	89690565	16	+	26627737	RPE1	viability after 15 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-1.6006233631832143	[993]	[164,22]	-7	hSpCas9	negative selection	1289861
89691871	89691894	16	-	26627737	RPE1	viability after 15 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-1.7315927239437081	[1577]	[82,183]	-8	hSpCas9	negative selection	1289862
89692475	89692498	16	-	26627737	RPE1	viability after 15 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	1.8699632688858383	[236]	[241,247]	8	hSpCas9	negative selection	1289863
89686775	89686798	16	+	26627737	RPE1	viability after 18 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	1.227191708461221	[518]	[426,221]	7	hSpCas9	negative selection	1372173
89687448	89687471	16	+	26627737	RPE1	viability after 18 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	3.4644622135354934	[230]	[1201,138]	9	hSpCas9	negative selection	1372174
89689285	89689308	16	+	26627737	RPE1	viability after 18 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.49990962278487583	[2000]	[479,276]	-3	hSpCas9	negative selection	1372175
89690542	89690565	16	+	26627737	RPE1	viability after 18 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.8401201075040452	[993]	[188,107]	-5	hSpCas9	negative selection	1372176
89691871	89691894	16	-	26627737	RPE1	viability after 18 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.9950805209196872	[1577]	[188,239]	-6	hSpCas9	negative selection	1372177
89692475	89692498	16	-	26627737	RPE1	viability after 18 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	1.4649722649651014	[236]	[90,267]	7	hSpCas9	negative selection	1372178
89686775	89686798	16	+	26627737	HeLa	viability after 8 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-1.2118219622479436	[944]	[329,189,54]	-8	hSpCas9	negative selection	1454488
89687448	89687471	16	+	26627737	HeLa	viability after 8 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.8817648814797436	[682]	[232,154,114]	-7	hSpCas9	negative selection	1454489
89689285	89689308	16	+	26627737	HeLa	viability after 8 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.5018617337530701	[623]	[240,240,109]	-5	hSpCas9	negative selection	1454490
89690542	89690565	16	+	26627737	HeLa	viability after 8 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.6681048145542781	[215]	[82,44,54]	-6	hSpCas9	negative selection	1454491
89691871	89691894	16	-	26627737	HeLa	viability after 8 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.5124756244659476	[507]	[119,60,267]	-5	hSpCas9	negative selection	1454492
89692475	89692498	16	-	26627737	HeLa	viability after 8 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.2369053775721127	[472]	[317,10,222]	-2	hSpCas9	negative selection	1454493
89686775	89686798	16	+	26627737	HeLa	viability after 12 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-2.455882776101946	[944]	[23,119,62]	-9	hSpCas9	negative selection	1536803
89687448	89687471	16	+	26627737	HeLa	viability after 12 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.9038770974179792	[682]	[173,86,198]	-7	hSpCas9	negative selection	1536804
89689285	89689308	16	+	26627737	HeLa	viability after 12 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.7940114604601503	[623]	[113,206,117]	-6	hSpCas9	negative selection	1536805
89690542	89690565	16	+	26627737	HeLa	viability after 12 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	0.4886964776890819	[215]	[156,93,128]	4	hSpCas9	negative selection	1536806
89691871	89691894	16	-	26627737	HeLa	viability after 12 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.10924992496061325	[507]	[158,267,245]	1	hSpCas9	negative selection	1536807
89692475	89692498	16	-	26627737	HeLa	viability after 12 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.880690777751304	[472]	[151,28,146]	-7	hSpCas9	negative selection	1536808
89686775	89686798	16	+	26627737	HeLa	viability after 15 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-1.7648183166651044	[944]	[62,118,161]	-9	hSpCas9	negative selection	1619118
89687448	89687471	16	+	26627737	HeLa	viability after 15 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.5211365481124324	[682]	[237,120,223]	-4	hSpCas9	negative selection	1619119
89689285	89689308	16	+	26627737	HeLa	viability after 15 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.1479820997644289	[623]	[313,151,219]	-1	hSpCas9	negative selection	1619120
89690542	89690565	16	+	26627737	HeLa	viability after 15 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	0.8898955368904302	[215]	[126,202,158]	6	hSpCas9	negative selection	1619121
89691871	89691894	16	-	26627737	HeLa	viability after 15 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.003390921103815392	[507]	[263,210,137]	0	hSpCas9	negative selection	1619122
89692475	89692498	16	-	26627737	HeLa	viability after 15 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.05545148509752562	[472]	[294,79,178]	0	hSpCas9	negative selection	1619123
89686775	89686798	16	+	26627737	HeLa	viability after 18 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-1.8107409771989307	[944]	[42,88,161]	-9	hSpCas9	negative selection	1701433
89687448	89687471	16	+	26627737	HeLa	viability after 18 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.5182423714074541	[682]	[158,101,223]	-4	hSpCas9	negative selection	1701434
89689285	89689308	16	+	26627737	HeLa	viability after 18 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.13757628593987892	[623]	[212,126,219]	-1	hSpCas9	negative selection	1701435
89690542	89690565	16	+	26627737	HeLa	viability after 18 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	0.8628602825215648	[215]	[76,170,158]	6	hSpCas9	negative selection	1701436
89691871	89691894	16	-	26627737	HeLa	viability after 18 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.010982143750931539	[507]	[177,170,137]	0	hSpCas9	negative selection	1701437
89692475	89692498	16	-	26627737	HeLa	viability after 18 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.012582411935729176	[472]	[212,60,178]	0	hSpCas9	negative selection	1701438
89686775	89686798	16	+	26627737	HCT116	viability after 6 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.722471057043359	[510]	[303,37]	4	hSpCas9	negative selection	1783748
89687448	89687471	16	+	26627737	HCT116	viability after 6 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.3177174595757915	[621]	[149,38]	-2	hSpCas9	negative selection	1783749
89689285	89689308	16	+	26627737	HCT116	viability after 6 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-2.004637101172693	[1119]	[117,2]	-8	hSpCas9	negative selection	1783750
89690542	89690565	16	+	26627737	HCT116	viability after 6 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.12794584054625976	[716]	[126,89]	0	hSpCas9	negative selection	1783751
89691871	89691894	16	-	26627737	HCT116	viability after 6 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-1.5581768898485986	[1044]	[136,10]	-7	hSpCas9	negative selection	1783752
89692475	89692498	16	-	26627737	HCT116	viability after 6 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.8668516117166439	[973]	[43,105]	-5	hSpCas9	negative selection	1783753
89686775	89686798	16	+	26627737	HCT116	viability after 8 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.2354294091973959	[313]	[175,182,250]	2	hSpCas9	negative selection	1866063
89687448	89687471	16	+	26627737	HCT116	viability after 8 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-1.2709158334715571	[495]	[113,129,95]	-9	hSpCas9	negative selection	1866064
89689285	89689308	16	+	26627737	HCT116	viability after 8 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	0.2376506707869936	[350]	[268,198,216]	2	hSpCas9	negative selection	1866065
89690542	89690565	16	+	26627737	HCT116	viability after 8 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.35752252318155603	[228]	[132,57,104]	-4	hSpCas9	negative selection	1866066
89691871	89691894	16	-	26627737	HCT116	viability after 8 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.6515340999794456	[326]	[278,364,205]	6	hSpCas9	negative selection	1866067
89692475	89692498	16	-	26627737	HCT116	viability after 8 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	0.10032489417115809	[205]	[140,151,72]	1	hSpCas9	negative selection	1866068
89686775	89686798	16	+	26627737	HCT116	viability after 9 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.39496232331728975	[510]	[308,76]	3	hSpCas9	negative selection	1948378
89687448	89687471	16	+	26627737	HCT116	viability after 9 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	0.05154132414512379	[621]	[251,108]	0	hSpCas9	negative selection	1948379
89689285	89689308	16	+	26627737	HCT116	viability after 9 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.8529384205578424	[1119]	[264,86]	-5	hSpCas9	negative selection	1948380
89690542	89690565	16	+	26627737	HCT116	viability after 9 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.8471675896510004	[716]	[130,86]	-5	hSpCas9	negative selection	1948381
89691871	89691894	16	-	26627737	HCT116	viability after 9 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.05515613155319954	[1044]	[410,155]	0	hSpCas9	negative selection	1948382
89692475	89692498	16	-	26627737	HCT116	viability after 9 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-1.5640952014236156	[973]	[54,113]	-8	hSpCas9	negative selection	1948383
89686775	89686798	16	+	26627737	HCT116	viability after 12 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.6410974333643269	[313]	[363,229,167]	6	hSpCas9	negative selection	2030693
89687448	89687471	16	+	26627737	HCT116	viability after 12 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.9895554443432568	[495]	[90,115,189]	-8	hSpCas9	negative selection	2030694
89689285	89689308	16	+	26627737	HCT116	viability after 12 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	0.2753024769618707	[350]	[174,265,233]	3	hSpCas9	negative selection	2030695
89690542	89690565	16	+	26627737	HCT116	viability after 12 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.20362613839304095	[228]	[147,75,84]	-2	hSpCas9	negative selection	2030696
89691871	89691894	16	-	26627737	HCT116	viability after 12 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.3039895933969228	[326]	[124,330,190]	3	hSpCas9	negative selection	2030697
89692475	89692498	16	-	26627737	HCT116	viability after 12 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	0.45510863066092894	[205]	[113,137,195]	4	hSpCas9	negative selection	2030698
89686775	89686798	16	+	26627737	HCT116	viability after 15 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.6456701829511039	[313]	[325,268,256]	6	hSpCas9	negative selection	2113008
89687448	89687471	16	+	26627737	HCT116	viability after 15 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-1.5469605678170315	[495]	[134,62,98]	-8	hSpCas9	negative selection	2113009
89689285	89689308	16	+	26627737	HCT116	viability after 15 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	0.0421515201050614	[350]	[219,181,221]	0	hSpCas9	negative selection	2113010
89690542	89690565	16	+	26627737	HCT116	viability after 15 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.16597920735934085	[228]	[229,68,66]	-2	hSpCas9	negative selection	2113011
89691871	89691894	16	-	26627737	HCT116	viability after 15 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.7070731941065368	[326]	[193,237,471]	6	hSpCas9	negative selection	2113012
89692475	89692498	16	-	26627737	HCT116	viability after 15 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	0.10096113768892151	[205]	[109,175,92]	1	hSpCas9	negative selection	2113013
89686775	89686798	16	+	26627737	HCT116	viability after 18 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.010284713377516672	[313]	[100,256,90]	0	hSpCas9	negative selection	2195323
89687448	89687471	16	+	26627737	HCT116	viability after 18 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.7358615425508843	[495]	[104,73,262]	-6	hSpCas9	negative selection	2195324
89689285	89689308	16	+	26627737	HCT116	viability after 18 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	0.3077661664527873	[350]	[328,187,109]	2	hSpCas9	negative selection	2195325
89690542	89690565	16	+	26627737	HCT116	viability after 18 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.5269143949247104	[228]	[98,54,77]	-5	hSpCas9	negative selection	2195326
89691871	89691894	16	-	26627737	HCT116	viability after 18 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.6819175316933577	[326]	[111,241,414]	5	hSpCas9	negative selection	2195327
89692475	89692498	16	-	26627737	HCT116	viability after 18 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	0.8480684002005019	[205]	[258,144,133]	6	hSpCas9	negative selection	2195328
89690593	89690616	16	+	24336569	HL60	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.6572057997495588	[1268]	[4234]	5	hSpCas9	negative selection	2256575
89690599	89690622	16	+	24336569	HL60	viability	GGTGCGGATGGACAAGGAGAAGG	CDK10	ENSG00000185324	1.0611879706633123	[711]	[3143]	7	hSpCas9	negative selection	2256576
89691448	89691471	16	-	24336569	HL60	viability	ATCTCCCGCAAGCTGCTGATGGG	CDK10	ENSG00000185324	1.2476895270959891	[238]	[1200]	8	hSpCas9	negative selection	2256577
89691483	89691506	16	-	24336569	HL60	viability	CGATGTTCGGATGACGCAGGCGG	CDK10	ENSG00000185324	1.4755312487558365	[598]	[3524]	8	hSpCas9	negative selection	2256578
89691495	89691518	16	+	24336569	HL60	viability	TCCGAACATCGTGGAGCTGAAGG	CDK10	ENSG00000185324	1.433439927618179	[980]	[5606]	8	hSpCas9	negative selection	2256579
89691501	89691524	16	+	24336569	HL60	viability	CATCGTGGAGCTGAAGGAGGTGG	CDK10	ENSG00000185324	1.454409677403443	[1110]	[6442]	8	hSpCas9	negative selection	2256580
89691507	89691530	16	+	24336569	HL60	viability	GGAGCTGAAGGAGGTGGTTGTGG	CDK10	ENSG00000185324	0.4590052999069769	[910]	[2649]	4	hSpCas9	negative selection	2256581
89691534	89691557	16	-	24336569	HL60	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.8658613593788607	[773]	[2984]	7	hSpCas9	negative selection	2256582
89691800	89691823	16	+	24336569	HL60	viability	TTCCAGCATCTTCCTGGTGATGG	CDK10	ENSG00000185324	0.5202376166366368	[456]	[1386]	4	hSpCas9	negative selection	2256583
89691812	89691835	16	-	24336569	HL60	viability	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	0.7491365656485398	[685]	[2439]	6	hSpCas9	negative selection	2256584
89690593	89690616	16	+	24336569	KBM7	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	-0.3763668040496957	[750]	[1577]	-3	hSpCas9	negative selection	2323752
89690599	89690622	16	+	24336569	KBM7	viability	GGTGCGGATGGACAAGGAGAAGG	CDK10	ENSG00000185324	-2.0106585793715888	[915]	[619]	-8	hSpCas9	negative selection	2323753
89691448	89691471	16	-	24336569	KBM7	viability	ATCTCCCGCAAGCTGCTGATGGG	CDK10	ENSG00000185324	0.39162459154806134	[319]	[1144]	3	hSpCas9	negative selection	2323754
89691483	89691506	16	-	24336569	KBM7	viability	CGATGTTCGGATGACGCAGGCGG	CDK10	ENSG00000185324	-0.8143615272205054	[685]	[1063]	-6	hSpCas9	negative selection	2323755
89691495	89691518	16	+	24336569	KBM7	viability	TCCGAACATCGTGGAGCTGAAGG	CDK10	ENSG00000185324	0.013128740059331623	[718]	[1978]	0	hSpCas9	negative selection	2323756
89691501	89691524	16	+	24336569	KBM7	viability	CATCGTGGAGCTGAAGGAGGTGG	CDK10	ENSG00000185324	-1.235460629468933	[1066]	[1235]	-7	hSpCas9	negative selection	2323757
89691507	89691530	16	+	24336569	KBM7	viability	GGAGCTGAAGGAGGTGGTTGTGG	CDK10	ENSG00000185324	-2.2412225235962233	[1020]	[588]	-8	hSpCas9	negative selection	2323758
89691534	89691557	16	-	24336569	KBM7	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.8746177932979214	[844]	[1256]	-6	hSpCas9	negative selection	2323759
89691800	89691823	16	+	24336569	KBM7	viability	TTCCAGCATCTTCCTGGTGATGG	CDK10	ENSG00000185324	-0.5587485724853548	[417]	[773]	-4	hSpCas9	negative selection	2323760
89691812	89691835	16	-	24336569	KBM7	viability	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	-0.29314243801864637	[384]	[856]	-2	hSpCas9	negative selection	2323761
89689005	89689028	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGAGAATCACTTGAACCCAGG	CDK10	ENSG00000185324	-0.9245662108867054	[38,121]	[11,5]	-5	dCas9-VP64	positive selection	2436945
89681050	89681073	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCCACTTCCTGG	CDK10	ENSG00000185324	-0.2161485283045399	[306,330]	[36,85]	-1	dCas9-VP64	positive selection	2459297
89691218	89691241	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCGGTGAGCCGAGATGG	CDK10	ENSG00000185324	2.3233621518244867	[14,12]	[9,20]	7	dCas9-VP64	positive selection	2460601
89689005	89689028	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGAGAATCACTTGAACCCAGG	CDK10	ENSG00000185324	-0.8437819202675474	[206,112]	[32,24]	-7	dCas9-VP64	positive selection	2532200
89681050	89681073	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCCACTTCCTGG	CDK10	ENSG00000185324	0.9402930649503107	[330,263]	[213,160]	6	dCas9-VP64	positive selection	2554552
89691218	89691241	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCGGTGAGCCGAGATGG	CDK10	ENSG00000185324	1.0057399992234806	[75,12]	[21,35]	6	dCas9-VP64	positive selection	2555856
89693291	89693314	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACTTGCTCATGACCGACAAGGG	CDK10	ENSG00000185324	0.023525101855664088	[2,3]	[3,1]	0	hSpCas9	positive selection	2978144
89691534	89691557	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.468899443750842	[4,3]	[3,1]	-6	hSpCas9	positive selection	2978145
89691812	89691835	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	-0.20486042623124923	[4,5]	[4,2]	-3	hSpCas9	positive selection	2978146
89691848	89691871	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGTTGGCATATTCTCCAGGAGG	CDK10	ENSG00000185324	0.33812263468424664	[4,4]	[3,6]	7	hSpCas9	positive selection	2978147
89693291	89693314	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACTTGCTCATGACCGACAAGGG	CDK10	ENSG00000185324	-0.49152047293834966	[2,2]	[2,0]	-7	hSpCas9	positive selection	3046002
89691534	89691557	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.1467364231427841	[4,4]	[3,1]	-2	hSpCas9	positive selection	3046003
89691812	89691835	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	0.13266204169578677	[4,4]	[5,2]	2	hSpCas9	positive selection	3046004
89691848	89691871	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGTTGGCATATTCTCCAGGAGG	CDK10	ENSG00000185324	0.07826701994760393	[4,4]	[4,2]	1	hSpCas9	positive selection	3046005
89695282	89695305		+	24336571	A375	resistance to PLX after 7 days	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.22506443119231637	[9,8]	[9,11]	6	hSpCas9	positive selection	3104561
89695322	89695345		-	24336571	A375	resistance to PLX after 7 days	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.07673778098650455	[10,11]	[9,10]	-2	hSpCas9	positive selection	3104562
89695049	89695072		+	24336571	A375	resistance to PLX after 7 days	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.16589876498733905	[10,11]	[13,11]	5	hSpCas9	positive selection	3104563
89695282	89695305		+	24336571	A375	resistance to PLX after 14 days	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.3756566828641089	[7,9]	[3,6]	3	hSpCas9	positive selection	3162354
89695322	89695345		-	24336571	A375	resistance to PLX after 14 days	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.7450706071603218	[10,15]	[3,2]	-8	hSpCas9	positive selection	3162355
89695049	89695072		+	24336571	A375	resistance to PLX after 14 days	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.6284959976316844	[9,12]	[2,2]	-7	hSpCas9	positive selection	3162356
89695282	89695305		+	24336571	A375	viability after 7 days	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.05017511445560918	[9]	[9,8]	0	hSpCas9	negative selection	3220147
89695322	89695345		-	24336571	A375	viability after 7 days	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.08784877119368835	[12]	[10,11]	-1	hSpCas9	negative selection	3220148
89695049	89695072		+	24336571	A375	viability after 7 days	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.8184808529090545	[21]	[10,11]	-8	hSpCas9	negative selection	3220149
89695282	89695305		+	24336571	A375	viability after 14 days	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.07434547516710777	[9]	[7,9]	-1	hSpCas9	negative selection	3277940
89695322	89695345		-	24336571	A375	viability after 14 days	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.18720679821367978	[12]	[10,15]	2	hSpCas9	negative selection	3277941
89695049	89695072		+	24336571	A375	viability after 14 days	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.7971200528420079	[21]	[9,12]	-7	hSpCas9	negative selection	3277942
89689244	89689267	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	2.149485204886942	[31,36]	[0,0]	7	hSpCas9	positive selection	3342369
89689310	89689333	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-1.4128093031277384	[384,429]	[0,0]	-8	hSpCas9	positive selection	3342370
89695049	89695072	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.4824960959604269	[109,108]	[0,0]	2	hSpCas9	positive selection	3342371
89695282	89695305	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	3.935398116558473	[9,9]	[0,0]	9	hSpCas9	positive selection	3361601
89695322	89695345	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	1.8310614567437373	[42,42]	[0,0]	7	hSpCas9	positive selection	3361602
89695006	89695029	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.7978945928085378	[87,87]	[0,0]	4	hSpCas9	positive selection	3361603
89693290	89693313	16	+	26780180	HT29	viability (Avana library 4 designs)	AACTTGCTCATGACCGACAAGGG	CDK10	ENSG00000185324	0.817417840828196	[]	[]	3	hSpCas9	negative selection	3414455
89691534	89691557	16	-	26780180	HT29	viability (Avana library 4 designs)	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.977732162020328	[]	[]	4	hSpCas9	negative selection	3414456
89691812	89691835	16	-	26780180	HT29	viability (Avana library 4 designs)	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	-0.1076778431762	[]	[]	-2	hSpCas9	negative selection	3414457
89691848	89691871	16	-	26780180	HT29	viability (Avana library 4 designs)	GTGTTGGCATATTCTCCAGGAGG	CDK10	ENSG00000185324	-0.234044963003161	[]	[]	-4	hSpCas9	negative selection	3414458
89691848	89691871	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTTGGCATATTCTCCAGGAGG	CDK10	ENSG00000185324	-1.36655110419932	[]	[]	-2	hSpCas9	negative selection	3490980
89691534	89691557	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-3.84695439926449	[]	[]	-4	hSpCas9	negative selection	3490981
89693290	89693313	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACTTGCTCATGACCGACAAGGG	CDK10	ENSG00000185324	-2.88743959011188	[]	[]	-3	hSpCas9	negative selection	3490982
89691812	89691835	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	1.33054588449925	[]	[]	1	hSpCas9	negative selection	3490983
89691483	89691506	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGATGTTCGGATGACGCAGGCGG	CDK10	ENSG00000185324	1.67498884754048	[]	[]	2	hSpCas9	negative selection	3490984
89693446	89693469	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGAGAGTGACCACCTTGGGGG	CDK10	ENSG00000185324	3.25608215605027	[]	[]	5	hSpCas9	negative selection	3490985
89691848	89691871	16	-	26780180	A375	viability (Avana lentiGuide)	GTGTTGGCATATTCTCCAGGAGG	CDK10	ENSG00000185324	-1.16547342751526	[]	[]	-2	hSpCas9	negative selection	3599639
89691534	89691557	16	-	26780180	A375	viability (Avana lentiGuide)	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	12.5381993820616	[]	[]	7	hSpCas9	negative selection	3599640
89693290	89693313	16	+	26780180	A375	viability (Avana lentiGuide)	AACTTGCTCATGACCGACAAGGG	CDK10	ENSG00000185324	-0.697676602127538	[]	[]	-1	hSpCas9	negative selection	3599641
89691812	89691835	16	-	26780180	A375	viability (Avana lentiGuide)	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	1.42974304928311	[]	[]	1	hSpCas9	negative selection	3599642
89691483	89691506	16	-	26780180	A375	viability (Avana lentiGuide)	CGATGTTCGGATGACGCAGGCGG	CDK10	ENSG00000185324	0.11093221329127	[]	[]	0	hSpCas9	negative selection	3599643
89693446	89693469	16	-	26780180	A375	viability (Avana lentiGuide)	CCAGAGAGTGACCACCTTGGGGG	CDK10	ENSG00000185324	14.0644952809939	[]	[]	7	hSpCas9	negative selection	3599644
89691848	89691871	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTTGGCATATTCTCCAGGAGG	CDK10	ENSG00000185324	0.01369084586623276	[6]	[6,5]	0	hSpCas9	positive selection	3708298
89691534	89691557	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.26063479476704415	[4]	[5,2]	-4	hSpCas9	positive selection	3708299
89693290	89693313	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTTGCTCATGACCGACAAGGG	CDK10	ENSG00000185324	-0.3875014782575663	[4]	[2,3]	-5	hSpCas9	positive selection	3708300
89691812	89691835	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	0.0018425909771549037	[5]	[5,5]	0	hSpCas9	positive selection	3708301
89691483	89691506	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGATGTTCGGATGACGCAGGCGG	CDK10	ENSG00000185324	0.3161604331805025	[4]	[5,5]	8	hSpCas9	positive selection	3708302
89693446	89693469	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGAGAGTGACCACCTTGGGGG	CDK10	ENSG00000185324	0.11407328736115277	[4]	[4,4]	3	hSpCas9	positive selection	3708303
89691848	89691871	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTTGGCATATTCTCCAGGAGG	CDK10	ENSG00000185324	-0.10821750151151198	[6]	[4,5]	-1	hSpCas9	positive selection	3816905
89691534	89691557	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.9758345900283705	[5]	[1,2]	-8	hSpCas9	positive selection	3816906
89693290	89693313	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTTGCTCATGACCGACAAGGG	CDK10	ENSG00000185324	-0.6047047572779805	[4]	[1,3]	-6	hSpCas9	positive selection	3816907
89691812	89691835	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCACAGTAACCCATCACCAGG	CDK10	ENSG00000185324	0.21250752447168741	[6]	[6,6]	5	hSpCas9	positive selection	3816908
89691483	89691506	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGATGTTCGGATGACGCAGGCGG	CDK10	ENSG00000185324	-0.3601640183178846	[4]	[4,1]	-5	hSpCas9	positive selection	3816909
89693446	89693469	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGAGAGTGACCACCTTGGGGG	CDK10	ENSG00000185324	-0.1283732131131897	[4]	[3,2]	-2	hSpCas9	positive selection	3816910
89695006	89695029	16	-	26780180	A375	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	1.36014188931569	[]	[]	7	hSpCas9	negative selection	3925074
89689310	89689333	16	-	26780180	A375	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	1.41645119170561	[]	[]	7	hSpCas9	negative selection	3925075
89695282	89695305	16	+	26780180	A375	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.348307377633223	[]	[]	0	hSpCas9	negative selection	3925076
89695322	89695345	16	-	26780180	A375	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	1.17783613183101	[]	[]	6	hSpCas9	negative selection	3925077
89695049	89695072	16	+	26780180	A375	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.885842965222175	[]	[]	4	hSpCas9	negative selection	3925078
89689244	89689267	16	+	26780180	A375	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.770406139454061	[]	[]	3	hSpCas9	negative selection	3925079
89695006	89695029	16	-	26780180	HT29	viability (GeCKOv2 library)	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.635629472394028	[]	[]	2	hSpCas9	negative selection	4033040
89689310	89689333	16	-	26780180	HT29	viability (GeCKOv2 library)	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.451004267783708	[]	[]	1	hSpCas9	negative selection	4033041
89695282	89695305	16	+	26780180	HT29	viability (GeCKOv2 library)	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.549732654293662	[]	[]	1	hSpCas9	negative selection	4033042
89695322	89695345	16	-	26780180	HT29	viability (GeCKOv2 library)	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.93012156018405	[]	[]	4	hSpCas9	negative selection	4033043
89695049	89695072	16	+	26780180	HT29	viability (GeCKOv2 library)	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	1.16197558015083	[]	[]	5	hSpCas9	negative selection	4033044
89689244	89689267	16	+	26780180	HT29	viability (GeCKOv2 library)	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	1.44290513614845	[]	[]	7	hSpCas9	negative selection	4033045
89695282	89695305	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.17622847078228412	[3]	[1,2]	-4	hSpCas9	positive selection	4126586
89695322	89695345	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.14895857772322701	[4]	[2,1]	-4	hSpCas9	positive selection	4126587
89695049	89695072	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.14423809758648795	[3]	[1,1]	-3	hSpCas9	positive selection	4126588
89695282	89695305	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.5439072160766474	[3]	[0,2,0,0]	-7	hSpCas9	positive selection	4190608
89695322	89695345	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.10225934195105105	[3]	[3,1,0,0]	0	hSpCas9	positive selection	4190609
89695049	89695072	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.5225724754278307	[4]	[4,2,2,0]	3	hSpCas9	positive selection	4190610
89689244	89689267	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.7914581332942278	[1]	[0,0]	-9	hSpCas9	positive selection	4262419
89689310	89689333	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.0817753429860128	[4]	[3,2]	1	hSpCas9	positive selection	4262420
89695049	89695072	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.08139622391288129	[2]	[2,1]	1	hSpCas9	positive selection	4262421
89695282	89695305	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.1734572510433321	[0]	[0,0]	-4	hSpCas9	positive selection	4326697
89695322	89695345	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.1714054598750291	[1]	[1,0]	-3	hSpCas9	positive selection	4326698
89695006	89695029	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.27726508828543106	[2]	[1,0]	-5	hSpCas9	positive selection	4326699
89691871	89691893	16	-	27760321	OCIAML3	viability	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.4753179792207772	[763,570]	[360,386]	-5	hSpCas9	negative selection	4387991
89692499	89692521	16	+	27760321	OCIAML3	viability	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	-1.400862219661038	[325,293]	[56,136]	-8	hSpCas9	negative selection	4387992
89693290	89693312	16	+	27760321	OCIAML3	viability	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	0.012042257088505814	[749,651]	[580,512]	0	hSpCas9	negative selection	4387993
89693391	89693413	16	+	27760321	OCIAML3	viability	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.09795925936409522	[1025,896]	[677,965]	1	hSpCas9	negative selection	4387994
89694734	89694756	16	-	27760321	OCIAML3	viability	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	-1.4884194922001937	[614,481]	[150,152]	-8	hSpCas9	negative selection	4387995
89691871	89691893	16	-	27760321	OCIAML2	viability	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.6815430344200265	[763,570]	[218,484]	-6	hSpCas9	negative selection	4471454
89692499	89692521	16	+	27760321	OCIAML2	viability	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	-0.5193606420596188	[325,293]	[141,217]	-5	hSpCas9	negative selection	4471455
89693290	89693312	16	+	27760321	OCIAML2	viability	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	-0.44065712197357265	[749,651]	[424,405]	-5	hSpCas9	negative selection	4471456
89693391	89693413	16	+	27760321	OCIAML2	viability	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.10476524059985692	[1025,896]	[796,883]	1	hSpCas9	negative selection	4471457
89694734	89694756	16	-	27760321	OCIAML2	viability	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	-0.4429195865042115	[614,481]	[309,342]	-5	hSpCas9	negative selection	4471458
89691871	89691893	16	-	27760321	MV411	viability	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.5135199966083462	[763,570]	[203,458]	-4	hSpCas9	negative selection	4554917
89692499	89692521	16	+	27760321	MV411	viability	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	0.4510130519244459	[325,293]	[13,677]	3	hSpCas9	negative selection	4554918
89693290	89693312	16	+	27760321	MV411	viability	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	1.1873537273342625	[749,651]	[922,1242]	8	hSpCas9	negative selection	4554919
89693391	89693413	16	+	27760321	MV411	viability	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	1.170127437542609	[1025,896]	[749,2437]	8	hSpCas9	negative selection	4554920
89694734	89694756	16	-	27760321	MV411	viability	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.0773306935463065	[614,481]	[306,487]	0	hSpCas9	negative selection	4554921
89691871	89691893	16	-	27760321	HL60	viability	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.07595168912720696	[763,570]	[463,681]	0	hSpCas9	negative selection	4638380
89692499	89692521	16	+	27760321	HL60	viability	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	0.34655059144566347	[325,293]	[277,367]	4	hSpCas9	negative selection	4638381
89693290	89693312	16	+	27760321	HL60	viability	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	0.32940941301418614	[749,651]	[758,673]	4	hSpCas9	negative selection	4638382
89693391	89693413	16	+	27760321	HL60	viability	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.784534186794277	[1025,896]	[1164,1545]	8	hSpCas9	negative selection	4638383
89694734	89694756	16	-	27760321	HL60	viability	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.41940655542798716	[614,481]	[436,762]	5	hSpCas9	negative selection	4638384
89691871	89691893	16	-	27760321	HT1080	viability	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-4.036916510019551	[570,445]	[8,15]	-8	hSpCas9	negative selection	4721843
89692499	89692521	16	+	27760321	HT1080	viability	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	-0.5463327009082226	[293,229]	[49,94]	-2	hSpCas9	negative selection	4721844
89693290	89693312	16	+	27760321	HT1080	viability	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	-0.9670148703934474	[651,508]	[208,18]	-4	hSpCas9	negative selection	4721845
89693391	89693413	16	+	27760321	HT1080	viability	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.1550786578514256	[896,699]	[273,441]	0	hSpCas9	negative selection	4721846
89694734	89694756	16	-	27760321	HT1080	viability	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	-3.1229609526905655	[481,375]	[0,39]	-7	hSpCas9	negative selection	4721847
89691871	89691893	16	-	27760321	HT29	viability after 7 days	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.4624261197782864	[570,445]	[1174,874,696]	7	hSpCas9	negative selection	4805306
89692499	89692521	16	+	27760321	HT29	viability after 7 days	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	0.3562164731515784	[293,229]	[373,320,584]	5	hSpCas9	negative selection	4805307
89693290	89693312	16	+	27760321	HT29	viability after 7 days	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	-0.13423925768169442	[651,508]	[830,749,485]	-2	hSpCas9	negative selection	4805308
89693391	89693413	16	+	27760321	HT29	viability after 7 days	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.5873739260570405	[896,699]	[1933,1421,1331]	8	hSpCas9	negative selection	4805309
89694734	89694756	16	-	27760321	HT29	viability after 7 days	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.5013542904635511	[481,375]	[638,808,869]	7	hSpCas9	negative selection	4805310
89691871	89691893	16	-	27760321	HT29	viability after 25 days	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.44598831030153296	[570,445]	[758,694,936]	5	hSpCas9	negative selection	4888769
89692499	89692521	16	+	27760321	HT29	viability after 25 days	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	0.3595459581460362	[293,229]	[399,289,469]	4	hSpCas9	negative selection	4888770
89693290	89693312	16	+	27760321	HT29	viability after 25 days	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	0.3674582820103681	[651,508]	[698,996,882]	4	hSpCas9	negative selection	4888771
89693391	89693413	16	+	27760321	HT29	viability after 25 days	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.42724210541519714	[896,699]	[1233,1164,1285]	4	hSpCas9	negative selection	4888772
89694734	89694756	16	-	27760321	HT29	viability after 25 days	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.5363589123220146	[481,375]	[713,549,885]	6	hSpCas9	negative selection	4888773
89691871	89691893	16	-	27760321	HT29	viability after 22 days	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.5367627160029713	[570,445]	[1079,761,708]	6	hSpCas9	negative selection	4972232
89692499	89692521	16	+	27760321	HT29	viability after 22 days	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	-0.19603514751696355	[293,229]	[288,306,195]	-2	hSpCas9	negative selection	4972233
89693290	89693312	16	+	27760321	HT29	viability after 22 days	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	0.14473434321052114	[651,508]	[523,715,993]	1	hSpCas9	negative selection	4972234
89693391	89693413	16	+	27760321	HT29	viability after 22 days	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.6999101582375395	[896,699]	[1348,1388,1766]	7	hSpCas9	negative selection	4972235
89694734	89694756	16	-	27760321	HT29	viability after 22 days	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.47480115405721446	[481,375]	[815,471,776]	5	hSpCas9	negative selection	4972236
89691871	89691893	16	-	27760321	HT29	viability after 19 days	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.4516254294013816	[570,445]	[936,469,985]	4	hSpCas9	negative selection	5055695
89692499	89692521	16	+	27760321	HT29	viability after 19 days	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	0.03781867274723766	[293,229]	[507,269,170]	0	hSpCas9	negative selection	5055696
89693290	89693312	16	+	27760321	HT29	viability after 19 days	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	0.4308826210765514	[651,508]	[914,970,803]	4	hSpCas9	negative selection	5055697
89693391	89693413	16	+	27760321	HT29	viability after 19 days	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.4045995201479635	[896,699]	[1277,905,1439]	4	hSpCas9	negative selection	5055698
89694734	89694756	16	-	27760321	HT29	viability after 19 days	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.2764522567085479	[481,375]	[699,514,578]	2	hSpCas9	negative selection	5055699
89691871	89691893	16	-	27760321	HT29	viability after 16 days	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.46413829755703406	[570,445]	[1078,677,627]	5	hSpCas9	negative selection	5139158
89692499	89692521	16	+	27760321	HT29	viability after 16 days	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	0.05487456782940486	[293,229]	[420,325,176]	0	hSpCas9	negative selection	5139159
89693290	89693312	16	+	27760321	HT29	viability after 16 days	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	-0.27690400376450547	[651,508]	[474,585,539]	-3	hSpCas9	negative selection	5139160
89693391	89693413	16	+	27760321	HT29	viability after 16 days	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.6040873893390266	[896,699]	[1595,1435,1061]	7	hSpCas9	negative selection	5139161
89694734	89694756	16	-	27760321	HT29	viability after 16 days	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.3346138561875387	[481,375]	[825,431,582]	3	hSpCas9	negative selection	5139162
89691871	89691893	16	-	27760321	HT29	viability after 13 days	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.3626032228311651	[570,445]	[606,760,898]	4	hSpCas9	negative selection	5222621
89692499	89692521	16	+	27760321	HT29	viability after 13 days	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	-0.11702895501751837	[293,229]	[308,288,244]	-1	hSpCas9	negative selection	5222622
89693290	89693312	16	+	27760321	HT29	viability after 13 days	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	-0.011588577573859338	[651,508]	[1081,489,444]	0	hSpCas9	negative selection	5222623
89693391	89693413	16	+	27760321	HT29	viability after 13 days	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.5837360712057802	[896,699]	[1290,1673,1210]	7	hSpCas9	negative selection	5222624
89694734	89694756	16	-	27760321	HT29	viability after 13 days	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.15102241316516424	[481,375]	[613,481,560]	1	hSpCas9	negative selection	5222625
89691871	89691893	16	-	27760321	HT29	viability after 10 days	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.7165545405491465	[570,445]	[1166,1331,647]	8	hSpCas9	negative selection	5306084
89692499	89692521	16	+	27760321	HT29	viability after 10 days	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	-0.17538296773953038	[293,229]	[214,340,313]	-2	hSpCas9	negative selection	5306085
89693290	89693312	16	+	27760321	HT29	viability after 10 days	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	0.21744209169668471	[651,508]	[873,648,995]	3	hSpCas9	negative selection	5306086
89693391	89693413	16	+	27760321	HT29	viability after 10 days	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	0.5622993844069923	[896,699]	[1361,1537,1516]	7	hSpCas9	negative selection	5306087
89694734	89694756	16	-	27760321	HT29	viability after 10 days	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	0.4873068478328457	[481,375]	[849,838,569]	6	hSpCas9	negative selection	5306088
89691871	89691893	16	-	27760321	MOLM13	viability	CGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.7197170748490372	[763,570]	[243,211]	-4	hSpCas9	negative selection	5389547
89692499	89692521	16	+	27760321	MOLM13	viability	GAACTTCATTATCCACAGGTGG	CDK10	ENSG00000185324	0.2379787760250629	[325,293]	[305,120]	1	hSpCas9	negative selection	5389548
89693290	89693312	16	+	27760321	MOLM13	viability	AACTTGCTCATGACCGACAAGG	CDK10	ENSG00000185324	0.10973250765577702	[749,651]	[664,221]	0	hSpCas9	negative selection	5389549
89693391	89693413	16	+	27760321	MOLM13	viability	GCTGCAGCGGATTTCGGCCTGG	CDK10	ENSG00000185324	1.385932138372307	[1025,896]	[2314,647]	8	hSpCas9	negative selection	5389550
89694734	89694756	16	-	27760321	MOLM13	viability	CTGCACGATCAAGTCGATCTGG	CDK10	ENSG00000185324	-0.33874227860930656	[614,481]	[416,94]	-2	hSpCas9	negative selection	5389551
89686674	89686697	16	+	27661255	K562	viability	GCGCCTGCGCGCAAGAGAGGCGG	CDK10	ENSG00000185324	0.51030279720572	[345,550]	[531,483]	9	dCas9-KRAB	negative selection	5469867
89686695	89686718	16	+	27661255	K562	viability	GGGGCCAGCGCTCGGCATGGCGG	CDK10	ENSG00000185324	0.014076287579223745	[1822,1592]	[1501,1277]	0	dCas9-KRAB	negative selection	5469868
89689244	89689267	16	+	27260156	BXPC3	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.24632167141502825	[167]	[217,224,188,195]	5	hSpCas9	negative selection	5534879
89689310	89689333	16	-	27260156	BXPC3	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.05130573637095304	[1177]	[1055,924,1359,1473]	-1	hSpCas9	negative selection	5534880
89695049	89695072	16	+	27260156	BXPC3	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.21065009350240943	[337]	[380,445,327,486]	4	hSpCas9	negative selection	5534881
89695282	89695305	16	+	27260156	BXPC3	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.021318757500326413	[24]	[9,38,23,34]	0	hSpCas9	negative selection	5599157
89695322	89695345	16	-	27260156	BXPC3	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.08754982792097965	[164]	[144,129,166,216]	-2	hSpCas9	negative selection	5599158
89695006	89695029	16	-	27260156	BXPC3	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.11914846032994109	[216]	[190,150,316,350]	2	hSpCas9	negative selection	5599159
89689244	89689267	16	+	27260156	A673	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.04929477591166376	[167]	[178,221,238,132]	-1	hSpCas9	negative selection	5656130
89689310	89689333	16	-	27260156	A673	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.09814934047871637	[1177]	[1589,1472,1386,1619]	2	hSpCas9	negative selection	5656131
89695049	89695072	16	+	27260156	A673	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.04324909148252154	[337]	[444,429,411,385]	1	hSpCas9	negative selection	5656132
89695282	89695305	16	+	27260156	A673	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.20361840070575976	[24]	[13,8,24,56]	-5	hSpCas9	negative selection	5720408
89695322	89695345	16	-	27260156	A673	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.20242000991187847	[164]	[407,105,188,232]	5	hSpCas9	negative selection	5720409
89695006	89695029	16	-	27260156	A673	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.18682948867370142	[216]	[320,269,362,230]	4	hSpCas9	negative selection	5720410
89689244	89689267	16	+	27260156	A375	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.2241550988858565	[167]	[149,210,351,202]	3	hSpCas9	negative selection	5777381
89689310	89689333	16	-	27260156	A375	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.321585080578211	[1177]	[868,1392,996,1170]	-4	hSpCas9	negative selection	5777382
89695049	89695072	16	+	27260156	A375	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.148674650780229	[337]	[336,436,600,379]	2	hSpCas9	negative selection	5777383
89695282	89695305	16	+	27260156	A375	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-1.0682181122914747	[24]	[20,28,4,3]	-8	hSpCas9	negative selection	5841659
89695322	89695345	16	-	27260156	A375	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.3624886747649403	[164]	[348,281,175,194]	5	hSpCas9	negative selection	5841660
89695006	89695029	16	-	27260156	A375	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.6350142268565406	[216]	[189,156,117,183]	-7	hSpCas9	negative selection	5841661
89689244	89689267	16	+	27260156	COLO741	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.44372013912079966	[167]	[228,362,278]	8	hSpCas9	negative selection	5898632
89689310	89689333	16	-	27260156	COLO741	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.00029468107130825594	[1177]	[1491,1414,1595]	0	hSpCas9	negative selection	5898633
89695049	89695072	16	+	27260156	COLO741	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.03718126058983817	[337]	[485,400,382]	-1	hSpCas9	negative selection	5898634
89695282	89695305	16	+	27260156	COLO741	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-1.9441203675328138	[24]	[1,8,12]	-9	hSpCas9	negative selection	5962910
89695322	89695345	16	-	27260156	COLO741	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.15685514538803735	[164]	[339,259,121]	3	hSpCas9	negative selection	5962911
89695006	89695029	16	-	27260156	COLO741	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.07841561469178893	[216]	[243,255,283]	-2	hSpCas9	negative selection	5962912
89689244	89689267	16	+	27260156	CAL120	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.6688909695728685	[167]	[543,162,321]	8	hSpCas9	negative selection	6019883
89689310	89689333	16	-	27260156	CAL120	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.7266101707322411	[1177]	[665,783,1168]	-7	hSpCas9	negative selection	6019884
89695049	89695072	16	+	27260156	CAL120	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.4171360572287188	[337]	[623,339,726]	6	hSpCas9	negative selection	6019885
89695282	89695305	16	+	27260156	CAL120	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.07445903137545784	[24]	[38,18,31]	-1	hSpCas9	negative selection	6084161
89695322	89695345	16	-	27260156	CAL120	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.13844236827964918	[164]	[224,183,267]	2	hSpCas9	negative selection	6084162
89695006	89695029	16	-	27260156	CAL120	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.16742167925565976	[216]	[207,303,204]	-2	hSpCas9	negative selection	6084163
89689244	89689267	16	+	27260156	CADOES1	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.3127734838450009	[167]	[215,222,125,211]	5	hSpCas9	negative selection	6141134
89689310	89689333	16	-	27260156	CADOES1	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.06285429618010796	[1177]	[986,1124,1369,1093]	1	hSpCas9	negative selection	6141135
89695049	89695072	16	+	27260156	CADOES1	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.0035718359926758536	[337]	[356,248,361,284]	0	hSpCas9	negative selection	6141136
89695282	89695305	16	+	27260156	CADOES1	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.5233619935594827	[24]	[23,31,61,14]	8	hSpCas9	negative selection	6205412
89695322	89695345	16	-	27260156	CADOES1	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.3578990679060503	[164]	[91,129,138,117]	-6	hSpCas9	negative selection	6205413
89695006	89695029	16	-	27260156	CADOES1	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.07306189925765993	[216]	[302,185,171,186]	1	hSpCas9	negative selection	6205414
89689244	89689267	16	+	27260156	EWS502	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.3896549492256056	[167]	[235,218,274,199]	6	hSpCas9	negative selection	6262385
89689310	89689333	16	-	27260156	EWS502	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.2606947438184366	[1177]	[897,1069,973,1249]	-4	hSpCas9	negative selection	6262386
89695049	89695072	16	+	27260156	EWS502	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.2836272790643224	[337]	[214,319,478,162]	-5	hSpCas9	negative selection	6262387
89695282	89695305	16	+	27260156	EWS502	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.6017873346161742	[24]	[10,73,64,10]	9	hSpCas9	negative selection	6326663
89695322	89695345	16	-	27260156	EWS502	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.10625164857843195	[164]	[40,217,214,302]	1	hSpCas9	negative selection	6326664
89695006	89695029	16	-	27260156	EWS502	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.09105969223500199	[216]	[211,148,351,276]	1	hSpCas9	negative selection	6326665
89689244	89689267	16	+	27260156	EW8	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.029566973794682427	[167]	[283,81,71,121]	0	hSpCas9	negative selection	6383636
89689310	89689333	16	-	27260156	EW8	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.016088049198303533	[1177]	[1080,905,1056,811]	0	hSpCas9	negative selection	6383637
89695049	89695072	16	+	27260156	EW8	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.2088096755297017	[337]	[332,293,268,378]	4	hSpCas9	negative selection	6383638
89695282	89695305	16	+	27260156	EW8	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.003993200149022158	[24]	[41,8,14,17]	0	hSpCas9	negative selection	6447914
89695322	89695345	16	-	27260156	EW8	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.4437591452533656	[164]	[109,119,70,97]	-7	hSpCas9	negative selection	6447915
89695006	89695029	16	-	27260156	EW8	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.40809772996390503	[216]	[236,116,104,86]	-6	hSpCas9	negative selection	6447916
89689244	89689267	16	+	27260156	CORL105	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.2598957382442999	[167]	[159,90,245,173]	-5	hSpCas9	negative selection	6504887
89689310	89689333	16	-	27260156	CORL105	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.21917850251224835	[1177]	[1071,1448,1153,1049]	-4	hSpCas9	negative selection	6504888
89695049	89695072	16	+	27260156	CORL105	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.1978187225758074	[337]	[482,442,506,391]	3	hSpCas9	negative selection	6504889
89695282	89695305	16	+	27260156	CORL105	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.27954777654732377	[24]	[21,45,57,18]	5	hSpCas9	negative selection	6569165
89695322	89695345	16	-	27260156	CORL105	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.04442295072750624	[164]	[204,250,131,151]	-1	hSpCas9	negative selection	6569166
89695006	89695029	16	-	27260156	CORL105	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.006715435378540802	[216]	[176,254,418,192]	0	hSpCas9	negative selection	6569167
89689244	89689267	16	+	27260156	HS294T	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.7901459065605201	[167]	[33,38,36,40]	-8	hSpCas9	negative selection	6626138
89689310	89689333	16	-	27260156	HS294T	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.20465617524033952	[1177]	[254,421,496,422]	-3	hSpCas9	negative selection	6626139
89695049	89695072	16	+	27260156	HS294T	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.17819518489761033	[337]	[136,79,126,116]	-3	hSpCas9	negative selection	6626140
89695282	89695305	16	+	27260156	HS294T	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-1.7487023629391372	[24]	[1,0,3,4]	-9	hSpCas9	negative selection	6690416
89695322	89695345	16	-	27260156	HS294T	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.38881054511522595	[164]	[36,36,44,82]	-5	hSpCas9	negative selection	6690417
89695006	89695029	16	-	27260156	HS294T	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.4674206800713874	[216]	[55,56,54,77]	-6	hSpCas9	negative selection	6690418
89689244	89689267	16	+	27260156	HCC44	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.23242894366227795	[167]	[334,201,233,137]	4	hSpCas9	negative selection	6747389
89689310	89689333	16	-	27260156	HCC44	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.37496168579064204	[1177]	[1216,756,1509,764]	-5	hSpCas9	negative selection	6747390
89695049	89695072	16	+	27260156	HCC44	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.044794530131110066	[337]	[439,357,486,316]	0	hSpCas9	negative selection	6747391
89695282	89695305	16	+	27260156	HCC44	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.028723664449460173	[24]	[23,10,62,20]	0	hSpCas9	negative selection	6811667
89695322	89695345	16	-	27260156	HCC44	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.057478062591584944	[164]	[254,238,209,76]	0	hSpCas9	negative selection	6811668
89695006	89695029	16	-	27260156	HCC44	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.6269406536626041	[216]	[174,201,204,58]	-7	hSpCas9	negative selection	6811669
89689244	89689267	16	+	27260156	G402	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.38803468979671596	[167]	[542,171,184,208]	5	hSpCas9	negative selection	6868640
89689310	89689333	16	-	27260156	G402	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.35646443606429234	[1177]	[1843,1785,1767,1947]	4	hSpCas9	negative selection	6868641
89695049	89695072	16	+	27260156	G402	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.40417521535260226	[337]	[507,256,265,242]	-5	hSpCas9	negative selection	6868642
89695282	89695305	16	+	27260156	G402	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.22587038695126083	[24]	[98,9,0,39]	3	hSpCas9	negative selection	6932918
89695322	89695345	16	-	27260156	G402	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.07139161989979703	[164]	[319,73,267,191]	0	hSpCas9	negative selection	6932919
89695006	89695029	16	-	27260156	G402	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.10502372888578093	[216]	[130,158,253,409]	-1	hSpCas9	negative selection	6932920
89689244	89689267	16	+	27260156	L33	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.41503792802803297	[167]	[138,64,60,108]	-7	hSpCas9	negative selection	6989891
89689310	89689333	16	-	27260156	L33	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.11775941837852044	[1177]	[1301,483,875,1235]	2	hSpCas9	negative selection	6989892
89695049	89695072	16	+	27260156	L33	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.3441172715426153	[337]	[409,151,245,542]	7	hSpCas9	negative selection	6989893
89695282	89695305	16	+	27260156	L33	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.37811109008669064	[24]	[18,3,11,28]	-7	hSpCas9	negative selection	7054169
89695322	89695345	16	-	27260156	L33	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.04665529880717867	[164]	[135,66,126,180]	1	hSpCas9	negative selection	7054170
89695006	89695029	16	-	27260156	L33	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.02475045532012876	[216]	[151,146,137,154]	0	hSpCas9	negative selection	7054171
89689244	89689267	16	+	27260156	K562	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.31619344051548115	[167]	[305,159,58,220]	4	hSpCas9	negative selection	7111142
89689310	89689333	16	-	27260156	K562	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.3570932088459855	[1177]	[809,1210,609,667]	-4	hSpCas9	negative selection	7111143
89695049	89695072	16	+	27260156	K562	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.6921260748882417	[337]	[195,210,141,193]	-7	hSpCas9	negative selection	7111144
89695282	89695305	16	+	27260156	K562	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.2721801613542576	[24]	[7,65,0,1]	-3	hSpCas9	negative selection	7175420
89695322	89695345	16	-	27260156	K562	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.6618133048890373	[164]	[204,57,47,68]	-7	hSpCas9	negative selection	7175421
89695006	89695029	16	-	27260156	K562	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.649909331796579	[216]	[49,60,188,174]	-6	hSpCas9	negative selection	7175422
89689244	89689267	16	+	27260156	HT29	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.28523982095389044	[167]	[272,221,390,122]	5	hSpCas9	negative selection	7232393
89689310	89689333	16	-	27260156	HT29	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.041606555703541215	[1177]	[1721,1354,1614,1231]	0	hSpCas9	negative selection	7232394
89695049	89695072	16	+	27260156	HT29	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.05942599902461021	[337]	[376,577,492,287]	1	hSpCas9	negative selection	7232395
89695282	89695305	16	+	27260156	HT29	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.17015849423059848	[24]	[10,14,71,34]	3	hSpCas9	negative selection	7296671
89695322	89695345	16	-	27260156	HT29	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.4722748167250348	[164]	[514,274,213,141]	8	hSpCas9	negative selection	7296672
89695006	89695029	16	-	27260156	HT29	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.07325392463450986	[216]	[178,234,271,395]	1	hSpCas9	negative selection	7296673
89689244	89689267	16	+	27260156	MHHES1	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.1531221075980742	[167]	[210,280,95,116]	-3	hSpCas9	negative selection	7353644
89689310	89689333	16	-	27260156	MHHES1	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.07913764434493609	[1177]	[1206,1512,1203,1121]	-1	hSpCas9	negative selection	7353645
89695049	89695072	16	+	27260156	MHHES1	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.15346301909893717	[337]	[403,543,412,349]	3	hSpCas9	negative selection	7353646
89695282	89695305	16	+	27260156	MHHES1	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.09679348942792299	[24]	[91,7,0,24]	1	hSpCas9	negative selection	7417922
89695322	89695345	16	-	27260156	MHHES1	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.25627033051006287	[164]	[91,161,161,187]	-5	hSpCas9	negative selection	7417923
89695006	89695029	16	-	27260156	MHHES1	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.4864251772124768	[216]	[133,215,208,141]	-7	hSpCas9	negative selection	7417924
89689244	89689267	16	+	27260156	MEWO	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.09964727155225583	[167]	[248,130,140]	2	hSpCas9	negative selection	7474895
89689310	89689333	16	-	27260156	MEWO	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.18212171203586314	[1177]	[940,984,981]	-4	hSpCas9	negative selection	7474896
89695049	89695072	16	+	27260156	MEWO	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.21067856938545343	[337]	[392,361,347]	4	hSpCas9	negative selection	7474897
89695282	89695305	16	+	27260156	MEWO	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-2.625810946831961	[24]	[1,7,0]	-9	hSpCas9	negative selection	7539173
89695322	89695345	16	-	27260156	MEWO	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.042784373540171616	[164]	[133,191,145]	1	hSpCas9	negative selection	7539174
89695006	89695029	16	-	27260156	MEWO	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.0055093004738744344	[216]	[264,169,183]	0	hSpCas9	negative selection	7539175
89689244	89689267	16	+	27260156	LNCAPCLONEFGC	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.5843342484049476	[167]	[196,182,361,193]	8	hSpCas9	negative selection	7596146
89689310	89689333	16	-	27260156	LNCAPCLONEFGC	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.16375125519510858	[1177]	[809,997,1029,982]	-3	hSpCas9	negative selection	7596147
89695049	89695072	16	+	27260156	LNCAPCLONEFGC	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.02749381107412363	[337]	[322,214,356,319]	0	hSpCas9	negative selection	7596148
89695282	89695305	16	+	27260156	LNCAPCLONEFGC	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.6109535454198642	[24]	[15,0,26,17]	-7	hSpCas9	negative selection	7660424
89695322	89695345	16	-	27260156	LNCAPCLONEFGC	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.015627280214508543	[164]	[182,153,147,117]	0	hSpCas9	negative selection	7660425
89695006	89695029	16	-	27260156	LNCAPCLONEFGC	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.0889508707124338	[216]	[124,107,316,214]	-1	hSpCas9	negative selection	7660426
89689244	89689267	16	+	27260156	PANC0327	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.3232253757792991	[167]	[141,179,202,218]	5	hSpCas9	negative selection	7717397
89689310	89689333	16	-	27260156	PANC0327	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.3194796553822197	[1177]	[1273,809,568,739]	-5	hSpCas9	negative selection	7717398
89695049	89695072	16	+	27260156	PANC0327	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.39338492091882227	[337]	[383,412,350,425]	6	hSpCas9	negative selection	7717399
89695282	89695305	16	+	27260156	PANC0327	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.7178571407604286	[24]	[13,13,20,4]	-7	hSpCas9	negative selection	7781675
89695322	89695345	16	-	27260156	PANC0327	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.6597746157982713	[164]	[106,117,86,56]	-7	hSpCas9	negative selection	7781676
89695006	89695029	16	-	27260156	PANC0327	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.713895331580185	[216]	[245,35,62,145]	-7	hSpCas9	negative selection	7781677
89689244	89689267	16	+	27260156	NCIH2009	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.27972160363538534	[167]	[158,189,223]	-4	hSpCas9	negative selection	7838648
89689310	89689333	16	-	27260156	NCIH2009	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.7665041189046204	[1177]	[1173,893,874]	-7	hSpCas9	negative selection	7838649
89695049	89695072	16	+	27260156	NCIH2009	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.2229038886129246	[337]	[562,651,437]	3	hSpCas9	negative selection	7838650
89695282	89695305	16	+	27260156	NCIH2009	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.19171634803051685	[24]	[25,18,45]	-3	hSpCas9	negative selection	7902926
89695322	89695345	16	-	27260156	NCIH2009	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.17022281746929768	[164]	[295,148,341]	2	hSpCas9	negative selection	7902927
89695006	89695029	16	-	27260156	NCIH2009	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.4006813618278311	[216]	[214,267,201]	-5	hSpCas9	negative selection	7902928
89689244	89689267	16	+	27260156	NCIH1373	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.9570912151540674	[167]	[67,86,90,36]	-7	hSpCas9	negative selection	7959899
89689310	89689333	16	-	27260156	NCIH1373	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.29046584614374926	[1177]	[1115,1018,880,348]	-3	hSpCas9	negative selection	7959900
89695049	89695072	16	+	27260156	NCIH1373	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.31546146172472056	[337]	[582,212,234,61]	-3	hSpCas9	negative selection	7959901
89695282	89695305	16	+	27260156	NCIH1373	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.6282220124963551	[24]	[13,20,27,1]	-6	hSpCas9	negative selection	8024177
89695322	89695345	16	-	27260156	NCIH1373	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.10596637736825754	[164]	[180,366,69,40]	1	hSpCas9	negative selection	8024178
89695006	89695029	16	-	27260156	NCIH1373	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.3481077428668917	[216]	[87,156,172,89]	-3	hSpCas9	negative selection	8024179
89689244	89689267	16	+	27260156	PATU8902	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.23442267882428136	[167]	[191,170,76,410]	-2	hSpCas9	negative selection	8081150
89689310	89689333	16	-	27260156	PATU8902	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-1.020711376116154	[1177]	[661,1016,584,1053]	-7	hSpCas9	negative selection	8081151
89695049	89695072	16	+	27260156	PATU8902	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-1.0035298576284517	[337]	[41,183,463,183]	-7	hSpCas9	negative selection	8081152
89695282	89695305	16	+	27260156	PATU8902	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-1.0656121954590771	[24]	[0,2,3,67]	-7	hSpCas9	negative selection	8145428
89695322	89695345	16	-	27260156	PATU8902	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.022273717605943766	[164]	[100,242,220,356]	0	hSpCas9	negative selection	8145429
89695006	89695029	16	-	27260156	PATU8902	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-1.3238928158541714	[216]	[53,179,78,188]	-8	hSpCas9	negative selection	8145430
89689244	89689267	16	+	27260156	PANC1	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.17194197396299016	[167]	[273,225,68,98]	2	hSpCas9	negative selection	8202401
89689310	89689333	16	-	27260156	PANC1	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.07384120769011648	[1177]	[1007,1177,1121,973]	1	hSpCas9	negative selection	8202402
89695049	89695072	16	+	27260156	PANC1	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.6819866659859215	[337]	[531,526,437,382]	9	hSpCas9	negative selection	8202403
89695282	89695305	16	+	27260156	PANC1	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.0655829557362404	[24]	[14,2,56,5]	-1	hSpCas9	negative selection	8266679
89695322	89695345	16	-	27260156	PANC1	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.05739271121812739	[164]	[172,213,92,123]	0	hSpCas9	negative selection	8266680
89695006	89695029	16	-	27260156	PANC1	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.025032010889814327	[216]	[190,137,218,173]	0	hSpCas9	negative selection	8266681
89689244	89689267	16	+	27260156	PANC0813	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.0030498780161474226	[167]	[276,120,234,166]	0	hSpCas9	negative selection	8323652
89689310	89689333	16	-	27260156	PANC0813	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.31375020852574265	[1177]	[1143,1272,1058,984]	-5	hSpCas9	negative selection	8323653
89695049	89695072	16	+	27260156	PANC0813	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.06476987587035754	[337]	[465,422,322,316]	-1	hSpCas9	negative selection	8323654
89695282	89695305	16	+	27260156	PANC0813	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.8015482219928742	[24]	[6,14,76,98]	9	hSpCas9	negative selection	8387930
89695322	89695345	16	-	27260156	PANC0813	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.124596287520228	[164]	[151,220,134,198]	-2	hSpCas9	negative selection	8387931
89695006	89695029	16	-	27260156	PANC0813	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.6167697024824761	[216]	[121,177,182,176]	-7	hSpCas9	negative selection	8387932
89689244	89689267	16	+	27260156	RDES	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.24282489624506298	[167]	[211,242,274,171]	4	hSpCas9	negative selection	8444903
89689310	89689333	16	-	27260156	RDES	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.06126643631530104	[1177]	[1226,1064,1354,1588]	-1	hSpCas9	negative selection	8444904
89695049	89695072	16	+	27260156	RDES	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.3231169618619363	[337]	[455,488,516,471]	5	hSpCas9	negative selection	8444905
89695282	89695305	16	+	27260156	RDES	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.5454373291458579	[24]	[8,14,36,20]	-7	hSpCas9	negative selection	8509181
89695322	89695345	16	-	27260156	RDES	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.18028877736765336	[164]	[133,161,183,428]	3	hSpCas9	negative selection	8509182
89695006	89695029	16	-	27260156	RDES	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.0018411947083558644	[216]	[218,241,225,318]	0	hSpCas9	negative selection	8509183
89689244	89689267	16	+	27260156	PC3	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.3318830417306824	[167]	[112,135,474,253]	7	hSpCas9	negative selection	8566154
89689310	89689333	16	-	27260156	PC3	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.08507024643507388	[1177]	[829,1250,2403,990]	2	hSpCas9	negative selection	8566155
89695049	89695072	16	+	27260156	PC3	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	-0.03601148143791011	[337]	[210,357,623,249]	-1	hSpCas9	negative selection	8566156
89695282	89695305	16	+	27260156	PC3	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.10947431154263398	[24]	[20,2,21,45]	-2	hSpCas9	negative selection	8630432
89695322	89695345	16	-	27260156	PC3	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.20319501900128056	[164]	[92,100,526,201]	4	hSpCas9	negative selection	8630433
89695006	89695029	16	-	27260156	PC3	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.00620256554896681	[216]	[91,217,403,261]	0	hSpCas9	negative selection	8630434
89689244	89689267	16	+	27260156	PATU8988T	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.3060165967776918	[167]	[296,147,225,119]	5	hSpCas9	negative selection	8687405
89689310	89689333	16	-	27260156	PATU8988T	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.015014707264746185	[1177]	[1232,1247,952,1180]	0	hSpCas9	negative selection	8687406
89695049	89695072	16	+	27260156	PATU8988T	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.27106120892057983	[337]	[201,246,569,553]	4	hSpCas9	negative selection	8687407
89695282	89695305	16	+	27260156	PATU8988T	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-1.8517149633426264	[24]	[0,16,0,8]	-9	hSpCas9	negative selection	8751683
89695322	89695345	16	-	27260156	PATU8988T	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.243473808242318	[164]	[170,160,267,147]	4	hSpCas9	negative selection	8751684
89695006	89695029	16	-	27260156	PATU8988T	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.3721143915683264	[216]	[164,454,304,168]	6	hSpCas9	negative selection	8751685
89689244	89689267	16	+	27260156	T47D	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.14664511634249977	[167]	[189,247,225,198]	3	hSpCas9	negative selection	8808656
89689310	89689333	16	-	27260156	T47D	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.32040492606187043	[1177]	[1145,1101,1140,1002]	-6	hSpCas9	negative selection	8808657
89695049	89695072	16	+	27260156	T47D	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.13345827177729747	[337]	[484,301,533,415]	3	hSpCas9	negative selection	8808658
89695282	89695305	16	+	27260156	T47D	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	0.13621337359362506	[24]	[43,24,42,15]	3	hSpCas9	negative selection	8872934
89695322	89695345	16	-	27260156	T47D	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.1266772979133075	[164]	[228,188,217,204]	2	hSpCas9	negative selection	8872935
89695006	89695029	16	-	27260156	T47D	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.15875850671147052	[216]	[219,283,182,213]	-4	hSpCas9	negative selection	8872936
89689244	89689267	16	+	27260156	SU8686	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.09482247052960369	[167]	[163,122,231,205]	1	hSpCas9	negative selection	8929907
89689310	89689333	16	-	27260156	SU8686	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.19705854306389337	[1177]	[741,974,1061,1386]	-3	hSpCas9	negative selection	8929908
89695049	89695072	16	+	27260156	SU8686	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.07137244371612345	[337]	[357,331,353,365]	1	hSpCas9	negative selection	8929909
89695282	89695305	16	+	27260156	SU8686	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.25156099456782144	[24]	[11,39,3,25]	-4	hSpCas9	negative selection	8994185
89695322	89695345	16	-	27260156	SU8686	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.10061250249830778	[164]	[150,120,142,206]	-2	hSpCas9	negative selection	8994186
89695006	89695029	16	-	27260156	SU8686	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.26095800538713876	[216]	[134,272,151,142]	-4	hSpCas9	negative selection	8994187
89689244	89689267	16	+	27260156	SKES1	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.3438538788835548	[167]	[304,220,150,188]	7	hSpCas9	negative selection	9051158
89689310	89689333	16	-	27260156	SKES1	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.013439844668363454	[1177]	[1332,1212,1097,1044]	0	hSpCas9	negative selection	9051159
89695049	89695072	16	+	27260156	SKES1	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.2910012738225653	[337]	[511,479,362,323]	6	hSpCas9	negative selection	9051160
89695282	89695305	16	+	27260156	SKES1	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.20478368668861702	[24]	[41,14,14,16]	-4	hSpCas9	negative selection	9115436
89695322	89695345	16	-	27260156	SKES1	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.30526917145539856	[164]	[156,151,131,99]	-6	hSpCas9	negative selection	9115437
89695006	89695029	16	-	27260156	SKES1	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.05928993112529568	[216]	[408,159,199,156]	1	hSpCas9	negative selection	9115438
89689244	89689267	16	+	27260156	TOV112D	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.3476189034319863	[167]	[321,172,180,179]	6	hSpCas9	negative selection	9172409
89689310	89689333	16	-	27260156	TOV112D	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.11742079800125782	[1177]	[1281,1362,998,796]	-2	hSpCas9	negative selection	9172410
89695049	89695072	16	+	27260156	TOV112D	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.23607818763075555	[337]	[320,504,432,355]	4	hSpCas9	negative selection	9172411
89695282	89695305	16	+	27260156	TOV112D	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.0666019671834297	[24]	[12,1,39,33]	-1	hSpCas9	negative selection	9236687
89695322	89695345	16	-	27260156	TOV112D	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.18290125996183648	[164]	[143,100,108,214]	-4	hSpCas9	negative selection	9236688
89695006	89695029	16	-	27260156	TOV112D	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	-0.08766390867955631	[216]	[262,315,134,137]	-2	hSpCas9	negative selection	9236689
89689244	89689267	16	+	27260156	TC71	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	-0.1217790537311021	[167]	[155,177,165,161]	-3	hSpCas9	negative selection	9293660
89689310	89689333	16	-	27260156	TC71	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	0.08984479323146144	[1177]	[1401,1313,1275,1386]	2	hSpCas9	negative selection	9293661
89695049	89695072	16	+	27260156	TC71	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.26958945035980153	[337]	[308,506,414,524]	6	hSpCas9	negative selection	9293662
89695282	89695305	16	+	27260156	TC71	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	-0.12109111631584923	[24]	[16,39,26,13]	-3	hSpCas9	negative selection	9357938
89695322	89695345	16	-	27260156	TC71	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	-0.12684874935820822	[164]	[191,113,125,219]	-3	hSpCas9	negative selection	9357939
89695006	89695029	16	-	27260156	TC71	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.03835625539309473	[216]	[203,221,245,286]	1	hSpCas9	negative selection	9357940
89689244	89689267	16	+	27260156	TC32	viability	TGTTTCAGCTGGGACGATGCCGG	CDK10	ENSG00000185324	0.2880207988599064	[167]	[188,118,311,188]	5	hSpCas9	negative selection	9414911
89689310	89689333	16	-	27260156	TC32	viability	CCACTCACACACAATGCCGTAGG	CDK10	ENSG00000185324	-0.0055461853397040795	[1177]	[906,925,1272,1374]	0	hSpCas9	negative selection	9414912
89695049	89695072	16	+	27260156	TC32	viability	TCATGTACGACCCTAAGAAAAGG	CDK10	ENSG00000185324	0.03262734853577626	[337]	[262,190,398,510]	0	hSpCas9	negative selection	9414913
89695282	89695305	16	+	27260156	TC32	viability	GCCTCCTCCAGGGCGACGGCCGG	CDK10	ENSG00000185324	1.143094073432183	[24]	[18,77,75,27]	9	hSpCas9	negative selection	9479189
89695322	89695345	16	-	27260156	TC32	viability	TAGGGGCTTCTCCTTGAAATAGG	CDK10	ENSG00000185324	0.2272531628268768	[164]	[256,34,278,209]	4	hSpCas9	negative selection	9479190
89695006	89695029	16	-	27260156	TC32	viability	AGCCCGGCCTCCGACAGCCATGG	CDK10	ENSG00000185324	0.2463529139774696	[216]	[152,280,274,244]	4	hSpCas9	negative selection	9479191
89686775	89686798	16	+	27869803	HPAFII	viability after 27 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.4505837826396782	[452]	[212,141,NaN]	-3	hSpCas9	negative selection	9558986
89687448	89687471	16	+	27869803	HPAFII	viability after 27 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.07762888142190616	[226]	[57,158,NaN]	0	hSpCas9	negative selection	9558987
89689285	89689308	16	+	27869803	HPAFII	viability after 27 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.4594125532970921	[334]	[198,68,NaN]	-3	hSpCas9	negative selection	9558988
89690542	89690565	16	+	27869803	HPAFII	viability after 27 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-1.0039993000752148	[145]	[34,40,NaN]	-6	hSpCas9	negative selection	9558989
89691871	89691894	16	-	27869803	HPAFII	viability after 27 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-1.9359728860612542	[394]	[68,41,NaN]	-8	hSpCas9	negative selection	9558990
89692475	89692498	16	-	27869803	HPAFII	viability after 27 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.6222664594838121	[320]	[107,110,NaN]	-4	hSpCas9	negative selection	9558991
89686775	89686798	16	+	27869803	HPAFII	viability after 15 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.4892035798369768	[452]	[270,393,NaN]	-5	hSpCas9	negative selection	9641435
89687448	89687471	16	+	27869803	HPAFII	viability after 15 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.15708646237185134	[226]	[166,250,NaN]	-2	hSpCas9	negative selection	9641436
89689285	89689308	16	+	27869803	HPAFII	viability after 15 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.10336571214867102	[334]	[418,282,NaN]	-1	hSpCas9	negative selection	9641437
89690542	89690565	16	+	27869803	HPAFII	viability after 15 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.44461204065366144	[145]	[237,38,NaN]	-5	hSpCas9	negative selection	9641438
89691871	89691894	16	-	27869803	HPAFII	viability after 15 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-1.0173688061566826	[394]	[234,193,NaN]	-7	hSpCas9	negative selection	9641439
89692475	89692498	16	-	27869803	HPAFII	viability after 15 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.15876752503948194	[320]	[173,392,NaN]	-2	hSpCas9	negative selection	9641440
89686775	89686798	16	+	27869803	ASPC1	viability after 36 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.1273327353806079	[901]	[242,189,394]	-1	hSpCas9	negative selection	9723884
89687448	89687471	16	+	27869803	ASPC1	viability after 36 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	0.3004552979283245	[651]	[208,378,248]	3	hSpCas9	negative selection	9723885
89689285	89689308	16	+	27869803	ASPC1	viability after 36 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.8729081232974173	[810]	[215,98,153]	-7	hSpCas9	negative selection	9723886
89690542	89690565	16	+	27869803	ASPC1	viability after 36 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	0.06675500410845459	[421]	[141,233,97]	0	hSpCas9	negative selection	9723887
89691871	89691894	16	-	27869803	ASPC1	viability after 36 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	0.046382165523234264	[1028]	[166,525,386]	0	hSpCas9	negative selection	9723888
89692475	89692498	16	-	27869803	ASPC1	viability after 36 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-1.2825532546135756	[628]	[92,91,85]	-8	hSpCas9	negative selection	9723889
89686775	89686798	16	+	27869803	PATU8988S	viability after 35 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.15487892770191608	[719]	[243,276,NaN]	-2	hSpCas9	negative selection	9806333
89687448	89687471	16	+	27869803	PATU8988S	viability after 35 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.3309541501007783	[627]	[235,165,NaN]	-3	hSpCas9	negative selection	9806334
89689285	89689308	16	+	27869803	PATU8988S	viability after 35 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.9234063404600064	[660]	[81,198,NaN]	-7	hSpCas9	negative selection	9806335
89690542	89690565	16	+	27869803	PATU8988S	viability after 35 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.9372950630034759	[386]	[34,127,NaN]	-7	hSpCas9	negative selection	9806336
89691871	89691894	16	-	27869803	PATU8988S	viability after 35 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.665384079855706	[958]	[256,229,NaN]	-6	hSpCas9	negative selection	9806337
89692475	89692498	16	-	27869803	PATU8988S	viability after 35 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.655210329369937	[470]	[99,140,NaN]	-6	hSpCas9	negative selection	9806338
89686775	89686798	16	+	27869803	PATU8988S	viability after 31 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	0.20543986339700077	[719]	[290,381,NaN]	2	hSpCas9	negative selection	9888782
89687448	89687471	16	+	27869803	PATU8988S	viability after 31 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	-0.4672958740228187	[627]	[214,137,NaN]	-5	hSpCas9	negative selection	9888783
89689285	89689308	16	+	27869803	PATU8988S	viability after 31 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.05980879683855991	[660]	[185,337,NaN]	0	hSpCas9	negative selection	9888784
89690542	89690565	16	+	27869803	PATU8988S	viability after 31 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-0.9823085692595005	[386]	[23,146,NaN]	-7	hSpCas9	negative selection	9888785
89691871	89691894	16	-	27869803	PATU8988S	viability after 31 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.4358461302644508	[958]	[133,471,NaN]	-5	hSpCas9	negative selection	9888786
89692475	89692498	16	-	27869803	PATU8988S	viability after 31 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.23561115030960225	[470]	[111,219,NaN]	-3	hSpCas9	negative selection	9888787
89686775	89686798	16	+	27869803	HPAFII	viability after 35 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.38961145917141826	[452]	[167,182,NaN]	-2	hSpCas9	negative selection	9971231
89687448	89687471	16	+	27869803	HPAFII	viability after 35 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	0.04107970627131215	[226]	[2,247,NaN]	0	hSpCas9	negative selection	9971232
89689285	89689308	16	+	27869803	HPAFII	viability after 35 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.5366366485325996	[334]	[178,46,NaN]	-3	hSpCas9	negative selection	9971233
89690542	89690565	16	+	27869803	HPAFII	viability after 35 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-4.273357501100811	[145]	[0,6,NaN]	-9	hSpCas9	negative selection	9971234
89691871	89691894	16	-	27869803	HPAFII	viability after 35 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-0.9432354032757682	[394]	[95,112,NaN]	-5	hSpCas9	negative selection	9971235
89692475	89692498	16	-	27869803	HPAFII	viability after 35 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	0.2247041123223557	[320]	[92,298,NaN]	1	hSpCas9	negative selection	9971236
89686775	89686798	16	+	27869803	HPAFII	viability after 31 days	TCACGGTGCCTCCGGAACACAGG	CDK10	ENSG00000185324	-0.30119623778575966	[452]	[168,246,NaN]	-2	hSpCas9	negative selection	10053680
89687448	89687471	16	+	27869803	HPAFII	viability after 31 days	GATCGTGGCTGGATGACAACAGG	CDK10	ENSG00000185324	0.03709572349814341	[226]	[34,234,NaN]	0	hSpCas9	negative selection	10053681
89689285	89689308	16	+	27869803	HPAFII	viability after 31 days	AAGCTGAACCGCATTGGAGAGGG	CDK10	ENSG00000185324	-0.4914051055394816	[334]	[205,54,NaN]	-3	hSpCas9	negative selection	10053682
89690542	89690565	16	+	27869803	HPAFII	viability after 31 days	TTCCATTCCAGATCGGGCCCGGG	CDK10	ENSG00000185324	-1.8604841544028528	[145]	[23,20,NaN]	-8	hSpCas9	negative selection	10053683
89691871	89691894	16	-	27869803	HPAFII	viability after 31 days	ACGCACCTGAGCCTCCGAGAAGG	CDK10	ENSG00000185324	-1.5263543104950785	[394]	[75,77,NaN]	-7	hSpCas9	negative selection	10053684
89692475	89692498	16	-	27869803	HPAFII	viability after 31 days	TGTGCAGATACTGGAGGCCCCGG	CDK10	ENSG00000185324	-0.3062719492828222	[320]	[82,213,NaN]	-2	hSpCas9	negative selection	10053685
89691498	89691521	16	+	28162770	P31FUJ	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-0.5547302993017411	[59]	[47]	-5	hSpCas9	negative selection	10130559
89691486	89691509	16	+	28162770	P31FUJ	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.4156568998964527	[362]	[568]	4	hSpCas9	negative selection	10130560
89694713	89694736	16	-	28162770	P31FUJ	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	2.5745527176432255	[0]	[6]	9	hSpCas9	negative selection	10130561
89690593	89690616	16	+	28162770	P31FUJ	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	-0.058499917648413335	[840]	[948]	0	hSpCas9	negative selection	10130562
89692477	89692500	16	+	28162770	P31FUJ	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.6478397036932224	[151]	[113]	-5	hSpCas9	negative selection	10130563
89691449	89691472	16	-	28162770	P31FUJ	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	-0.09874128167968468	[266]	[292]	-1	hSpCas9	negative selection	10130564
89691534	89691557	16	-	28162770	P31FUJ	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.0473057147783567	[223]	[271]	0	hSpCas9	negative selection	10130565
89691860	89691883	16	+	28162770	P31FUJ	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.22094030786107433	[968]	[976]	-2	hSpCas9	negative selection	10130566
89694202	89694225	16	-	28162770	P31FUJ	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.37385536740609626	[43]	[66]	4	hSpCas9	negative selection	10130567
89690603	89690626	16	+	28162770	P31FUJ	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-1.5111033669014828	[113]	[46]	-7	hSpCas9	negative selection	10130568
89691498	89691521	16	+	28162770	TF1	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10299925
89691486	89691509	16	+	28162770	TF1	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	NaN	[NaN]	[339]	1	hSpCas9	negative selection	10299926
89694713	89694736	16	-	28162770	TF1	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10299927
89690593	89690616	16	+	28162770	TF1	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	NaN	[NaN]	[447]	1	hSpCas9	negative selection	10299928
89692477	89692500	16	+	28162770	TF1	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10299929
89691449	89691472	16	-	28162770	TF1	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	NaN	[NaN]	[219]	1	hSpCas9	negative selection	10299930
89691534	89691557	16	-	28162770	TF1	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10299931
89691860	89691883	16	+	28162770	TF1	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	NaN	[NaN]	[406]	1	hSpCas9	negative selection	10299932
89694202	89694225	16	-	28162770	TF1	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10299933
89690603	89690626	16	+	28162770	TF1	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10299934
89691498	89691521	16	+	28162770	SKM1	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-0.1781455082472807	[15]	[24]	-1	hSpCas9	negative selection	10469291
89691486	89691509	16	+	28162770	SKM1	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.3544959573437931	[72]	[164]	3	hSpCas9	negative selection	10469292
89694713	89694736	16	-	28162770	SKM1	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	0.9853532240355989	[1]	[6]	8	hSpCas9	negative selection	10469293
89690593	89690616	16	+	28162770	SKM1	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.6471692383903167	[254]	[705]	6	hSpCas9	negative selection	10469294
89692477	89692500	16	+	28162770	SKM1	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.6824708848387827	[42]	[121]	6	hSpCas9	negative selection	10469295
89691449	89691472	16	-	28162770	SKM1	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.7994866787242646	[64]	[199]	7	hSpCas9	negative selection	10469296
89691534	89691557	16	-	28162770	SKM1	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.2633897932086392	[40]	[86]	2	hSpCas9	negative selection	10469297
89691860	89691883	16	+	28162770	SKM1	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	0.4181063109622809	[184]	[436]	4	hSpCas9	negative selection	10469298
89694202	89694225	16	-	28162770	SKM1	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.9853532240355987	[15]	[55]	8	hSpCas9	negative selection	10469299
89690603	89690626	16	+	28162770	SKM1	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-3.2814333166593026	[32]	[5]	-9	hSpCas9	negative selection	10469300
89691498	89691521	16	+	28162770	SKM1	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-0.1781455082472807	[15]	[24]	-1	hSpCas9	negative selection	10638657
89691486	89691509	16	+	28162770	SKM1	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.3544959573437931	[72]	[164]	3	hSpCas9	negative selection	10638658
89694713	89694736	16	-	28162770	SKM1	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	0.9853532240355989	[1]	[6]	8	hSpCas9	negative selection	10638659
89690593	89690616	16	+	28162770	SKM1	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.6471692383903167	[254]	[705]	6	hSpCas9	negative selection	10638660
89692477	89692500	16	+	28162770	SKM1	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.6824708848387827	[42]	[121]	6	hSpCas9	negative selection	10638661
89691449	89691472	16	-	28162770	SKM1	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.7994866787242646	[64]	[199]	7	hSpCas9	negative selection	10638662
89691534	89691557	16	-	28162770	SKM1	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.2633897932086392	[40]	[86]	2	hSpCas9	negative selection	10638663
89691860	89691883	16	+	28162770	SKM1	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	0.4181063109622809	[184]	[436]	4	hSpCas9	negative selection	10638664
89694202	89694225	16	-	28162770	SKM1	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.9853532240355987	[15]	[55]	8	hSpCas9	negative selection	10638665
89690603	89690626	16	+	28162770	SKM1	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-3.2814333166593026	[32]	[5]	-9	hSpCas9	negative selection	10638666
89691498	89691521	16	+	28162770	PL21	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-2.7067509811191988	[44]	[2]	-9	hSpCas9	negative selection	10808023
89691486	89691509	16	+	28162770	PL21	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.7532532491711365	[228]	[167]	6	hSpCas9	negative selection	10808024
89694713	89694736	16	-	28162770	PL21	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	4.659571233126618	[0]	[10]	9	hSpCas9	negative selection	10808025
89690593	89690616	16	+	28162770	PL21	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.3517912168762569	[820]	[455]	3	hSpCas9	negative selection	10808026
89692477	89692500	16	+	28162770	PL21	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.2392820434164828	[178]	[65]	-2	hSpCas9	negative selection	10808027
89691449	89691472	16	-	28162770	PL21	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.5302882161816508	[244]	[153]	4	hSpCas9	negative selection	10808028
89691534	89691557	16	-	28162770	PL21	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.48893128957257453	[157]	[48]	-3	hSpCas9	negative selection	10808029
89691860	89691883	16	+	28162770	PL21	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	0.1523388936876171	[582]	[281]	1	hSpCas9	negative selection	10808030
89694202	89694225	16	-	28162770	PL21	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	-2.929143402455647	[69]	[3]	-9	hSpCas9	negative selection	10808031
89690603	89690626	16	+	28162770	PL21	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-1.4779322906233172	[95]	[14]	-7	hSpCas9	negative selection	10808032
89691498	89691521	16	+	28162770	P31FUJ	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-0.5547302993017411	[59]	[47]	-5	hSpCas9	negative selection	10977389
89691486	89691509	16	+	28162770	P31FUJ	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.4156568998964527	[362]	[568]	4	hSpCas9	negative selection	10977390
89694713	89694736	16	-	28162770	P31FUJ	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	2.5745527176432255	[0]	[6]	9	hSpCas9	negative selection	10977391
89690593	89690616	16	+	28162770	P31FUJ	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	-0.058499917648413335	[840]	[948]	0	hSpCas9	negative selection	10977392
89692477	89692500	16	+	28162770	P31FUJ	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.6478397036932224	[151]	[113]	-5	hSpCas9	negative selection	10977393
89691449	89691472	16	-	28162770	P31FUJ	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	-0.09874128167968468	[266]	[292]	-1	hSpCas9	negative selection	10977394
89691534	89691557	16	-	28162770	P31FUJ	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.0473057147783567	[223]	[271]	0	hSpCas9	negative selection	10977395
89691860	89691883	16	+	28162770	P31FUJ	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.22094030786107433	[968]	[976]	-2	hSpCas9	negative selection	10977396
89694202	89694225	16	-	28162770	P31FUJ	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.37385536740609626	[43]	[66]	4	hSpCas9	negative selection	10977397
89690603	89690626	16	+	28162770	P31FUJ	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-1.5111033669014828	[113]	[46]	-7	hSpCas9	negative selection	10977398
89691498	89691521	16	+	28162770	OCIAML5	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	1.076040510654217	[35]	[136]	8	hSpCas9	negative selection	11146755
89691486	89691509	16	+	28162770	OCIAML5	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	-0.011449194674644558	[195]	[350]	0	hSpCas9	negative selection	11146756
89694713	89694736	16	-	28162770	OCIAML5	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11146757
89690593	89690616	16	+	28162770	OCIAML5	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.8787729205053676	[353]	[1174]	7	hSpCas9	negative selection	11146758
89692477	89692500	16	+	28162770	OCIAML5	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.3563325783929511	[73]	[170]	3	hSpCas9	negative selection	11146759
89691449	89691472	16	-	28162770	OCIAML5	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.9783719643066482	[123]	[440]	8	hSpCas9	negative selection	11146760
89691534	89691557	16	-	28162770	OCIAML5	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.5203574551840493	[146]	[184]	-4	hSpCas9	negative selection	11146761
89691860	89691883	16	+	28162770	OCIAML5	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	0.19717694815585207	[431]	[893]	1	hSpCas9	negative selection	11146762
89694202	89694225	16	-	28162770	OCIAML5	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	-2.884488048556374	[89]	[21]	-8	hSpCas9	negative selection	11146763
89690603	89690626	16	+	28162770	OCIAML5	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-5.244383993642757	[62]	[2]	-9	hSpCas9	negative selection	11146764
89691498	89691521	16	+	28162770	EOL1	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-1.0376501957170814	[112]	[28]	-6	hSpCas9	negative selection	11316121
89691486	89691509	16	+	28162770	EOL1	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.18758217740432823	[329]	[197]	1	hSpCas9	negative selection	11316122
89694713	89694736	16	-	28162770	EOL1	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	0.40997459874077613	[9]	[6]	4	hSpCas9	negative selection	11316123
89690593	89690616	16	+	28162770	EOL1	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.8273915341163511	[1427]	[1334]	7	hSpCas9	negative selection	11316124
89692477	89692500	16	+	28162770	EOL1	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.6585958823544465	[296]	[246]	6	hSpCas9	negative selection	11316125
89691449	89691472	16	-	28162770	EOL1	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.3614683887478283	[457]	[309]	3	hSpCas9	negative selection	11316126
89691534	89691557	16	-	28162770	EOL1	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	1.2241080534294424	[181]	[223]	8	hSpCas9	negative selection	11316127
89691860	89691883	16	+	28162770	EOL1	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.3633966418541672	[922]	[377]	-3	hSpCas9	negative selection	11316128
89694202	89694225	16	-	28162770	EOL1	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	1.1714625120410513	[74]	[88]	8	hSpCas9	negative selection	11316129
89690603	89690626	16	+	28162770	EOL1	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	0.8420856113785617	[125]	[118]	7	hSpCas9	negative selection	11316130
89691498	89691521	16	+	28162770	MOLM13	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-2.307404331280727	[88]	[12]	-8	hSpCas9	negative selection	11485487
89691486	89691509	16	+	28162770	MOLM13	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	-0.6300857780187186	[395]	[184]	-4	hSpCas9	negative selection	11485488
89694713	89694736	16	-	28162770	MOLM13	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-1.5321106184554214	[3]	[0]	-6	hSpCas9	negative selection	11485489
89690593	89690616	16	+	28162770	MOLM13	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	-0.22438366324515258	[1122]	[694]	-1	hSpCas9	negative selection	11485490
89692477	89692500	16	+	28162770	MOLM13	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.6729731542952707	[257]	[116]	-4	hSpCas9	negative selection	11485491
89691449	89691472	16	-	28162770	MOLM13	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.7223106570736645	[419]	[500]	5	hSpCas9	negative selection	11485492
89691534	89691557	16	-	28162770	MOLM13	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-1.3823634989507392	[255]	[70]	-6	hSpCas9	negative selection	11485493
89691860	89691883	16	+	28162770	MOLM13	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.6496510397177198	[932]	[429]	-4	hSpCas9	negative selection	11485494
89694202	89694225	16	-	28162770	MOLM13	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	-0.7104478597139336	[42]	[18]	-4	hSpCas9	negative selection	11485495
89690603	89690626	16	+	28162770	MOLM13	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-1.3394655405130256	[181]	[51]	-6	hSpCas9	negative selection	11485496
89691498	89691521	16	+	28162770	HEL	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	0.49299171249567486	[70]	[63]	4	hSpCas9	negative selection	11654853
89691486	89691509	16	+	28162770	HEL	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	-0.7807011082741838	[286]	[106]	-5	hSpCas9	negative selection	11654854
89694713	89694736	16	-	28162770	HEL	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-0.942223668720799	[2]	[0]	-5	hSpCas9	negative selection	11654855
89690593	89690616	16	+	28162770	HEL	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.25301618517446434	[1110]	[847]	2	hSpCas9	negative selection	11654856
89692477	89692500	16	+	28162770	HEL	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.9431337653380779	[215]	[265]	7	hSpCas9	negative selection	11654857
89691449	89691472	16	-	28162770	HEL	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.7642254989223429	[386]	[420]	6	hSpCas9	negative selection	11654858
89691534	89691557	16	-	28162770	HEL	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.7296790333406984	[188]	[72]	-5	hSpCas9	negative selection	11654859
89691860	89691883	16	+	28162770	HEL	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.3622388441540283	[870]	[433]	-3	hSpCas9	negative selection	11654860
89694202	89694225	16	-	28162770	HEL	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.1612059209346064	[73]	[52]	1	hSpCas9	negative selection	11654861
89690603	89690626	16	+	28162770	HEL	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-4.401655287358096	[164]	[4]	-9	hSpCas9	negative selection	11654862
89691498	89691521	16	+	28162770	MV411	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	0.7779522674815551	[26]	[38]	7	hSpCas9	negative selection	11824219
89691486	89691509	16	+	28162770	MV411	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.24051813684298476	[208]	[207]	2	hSpCas9	negative selection	11824220
89694713	89694736	16	-	28162770	MV411	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11824221
89690593	89690616	16	+	28162770	MV411	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.40142919732127913	[869]	[967]	3	hSpCas9	negative selection	11824222
89692477	89692500	16	+	28162770	MV411	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	0.9266153931215821	[162]	[260]	8	hSpCas9	negative selection	11824223
89691449	89691472	16	-	28162770	MV411	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.22251991857844589	[291]	[286]	2	hSpCas9	negative selection	11824224
89691534	89691557	16	-	28162770	MV411	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	0.07751254934046292	[152]	[135]	0	hSpCas9	negative selection	11824225
89691860	89691883	16	+	28162770	MV411	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.19407215985725967	[549]	[404]	-1	hSpCas9	negative selection	11824226
89694202	89694225	16	-	28162770	MV411	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	-0.8207339518588039	[64]	[30]	-5	hSpCas9	negative selection	11824227
89690603	89690626	16	+	28162770	MV411	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-2.144879871995985	[125]	[23]	-8	hSpCas9	negative selection	11824228
89691498	89691521	16	+	28162770	MONOMAC1	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	0.47434040547907563	[26]	[42]	5	hSpCas9	negative selection	11993585
89691486	89691509	16	+	28162770	MONOMAC1	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	-0.10652455415411143	[138]	[147]	-1	hSpCas9	negative selection	11993586
89694713	89694736	16	-	28162770	MONOMAC1	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	11993587
89690593	89690616	16	+	28162770	MONOMAC1	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	-0.01475781361966666	[645]	[732]	0	hSpCas9	negative selection	11993588
89692477	89692500	16	+	28162770	MONOMAC1	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.12799520262990227	[101]	[106]	-1	hSpCas9	negative selection	11993589
89691449	89691472	16	-	28162770	MONOMAC1	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.3167646247403636	[186]	[266]	3	hSpCas9	negative selection	11993590
89691534	89691557	16	-	28162770	MONOMAC1	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.23236992017183425	[123]	[120]	-2	hSpCas9	negative selection	11993591
89691860	89691883	16	+	28162770	MONOMAC1	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-0.027496307988840618	[416]	[468]	0	hSpCas9	negative selection	11993592
89694202	89694225	16	-	28162770	MONOMAC1	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.7098537485489651	[23]	[44]	6	hSpCas9	negative selection	11993593
89690603	89690626	16	+	28162770	MONOMAC1	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-0.4738770524183781	[62]	[51]	-4	hSpCas9	negative selection	11993594
89691498	89691521	16	+	28162770	OCIAML2	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-0.05559232596331709	[8]	[47]	0	hSpCas9	negative selection	12162951
89691486	89691509	16	+	28162770	OCIAML2	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	0.22186113978344	[27]	[180]	2	hSpCas9	negative selection	12162952
89694713	89694736	16	-	28162770	OCIAML2	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-2.0555923259633175	[2]	[3]	-8	hSpCas9	negative selection	12162953
89690593	89690616	16	+	28162770	OCIAML2	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	-0.14870173035479883	[170]	[854]	-1	hSpCas9	negative selection	12162954
89692477	89692500	16	+	28162770	OCIAML2	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.9490927046626386	[30]	[88]	-6	hSpCas9	negative selection	12162955
89691449	89691472	16	-	28162770	OCIAML2	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.6203647069784315	[47]	[408]	6	hSpCas9	negative selection	12162956
89691534	89691557	16	-	28162770	OCIAML2	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.2585793481271722	[29]	[138]	-2	hSpCas9	negative selection	12162957
89691860	89691883	16	+	28162770	OCIAML2	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	-1.1576072835766906	[129]	[322]	-6	hSpCas9	negative selection	12162958
89694202	89694225	16	-	28162770	OCIAML2	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	-0.470629825242161	[8]	[35]	-4	hSpCas9	negative selection	12162959
89690603	89690626	16	+	28162770	OCIAML2	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-1.18683685924157	[22]	[55]	-7	hSpCas9	negative selection	12162960
89691498	89691521	16	+	28162770	OCIAML3	viability	GAACATCGTGGAGCTGAAGGAGG	CDK10	ENSG00000185324	-1.226275855823676	[30]	[39]	-7	hSpCas9	negative selection	12332317
89691486	89691509	16	+	28162770	OCIAML3	viability	CCTGCGTCATCCGAACATCGTGG	CDK10	ENSG00000185324	-0.6174666131481521	[61]	[121]	-5	hSpCas9	negative selection	12332318
89694713	89694736	16	-	28162770	OCIAML3	viability	GGTGGATCTCGGAAGTGCCGGGG	CDK10	ENSG00000185324	-4.178970141045319	[5]	[0]	-9	hSpCas9	negative selection	12332319
89690593	89690616	16	+	28162770	OCIAML3	viability	GAAGAAGGTGCGGATGGACAAGG	CDK10	ENSG00000185324	0.9997922236561698	[216]	[1309]	8	hSpCas9	negative selection	12332320
89692477	89692500	16	+	28162770	OCIAML3	viability	GGGGCCTCCAGTATCTGCACAGG	CDK10	ENSG00000185324	-0.03269640766765247	[40]	[120]	0	hSpCas9	negative selection	12332321
89691449	89691472	16	-	28162770	OCIAML3	viability	GATCTCCCGCAAGCTGCTGATGG	CDK10	ENSG00000185324	0.05209515521089725	[76]	[240]	0	hSpCas9	negative selection	12332322
89691534	89691557	16	-	28162770	OCIAML3	viability	AGACCACGTACCTCTCCAGGTGG	CDK10	ENSG00000185324	-0.9773362798756688	[44]	[68]	-6	hSpCas9	negative selection	12332323
89691860	89691883	16	+	28162770	OCIAML3	viability	TATGCCAACACCCTTCTCGGAGG	CDK10	ENSG00000185324	0.041661822426691364	[204]	[636]	0	hSpCas9	negative selection	12332324
89694202	89694225	16	-	28162770	OCIAML3	viability	GATGCTGGTGGTCTGCGTGGTGG	CDK10	ENSG00000185324	0.6076262208454872	[19]	[91]	5	hSpCas9	negative selection	12332325
89690603	89690626	16	+	28162770	OCIAML3	viability	CGGATGGACAAGGAGAAGGATGG	CDK10	ENSG00000185324	-1.1633732859943011	[22]	[30]	-7	hSpCas9	negative selection	12332326