Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:51265
• Symbol:CDKL3
• Description:cyclin dependent kinase like 3

DataSource: http://genomecrispr.dkfz.de/#!/results/CDKL3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
134308225	134308248	5	-	26472758	Jiyoye	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.38371640868188434	[123]	[121]	3	hSpCas9	negative selection	28941
134308354	134308377	5	-	26472758	Jiyoye	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	-0.6451456536242088	[364]	[175]	-4	hSpCas9	negative selection	28942
134359908	134359931	5	+	26472758	Jiyoye	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-0.7341804677396682	[149]	[67]	-5	hSpCas9	negative selection	28943
134321860	134321883	5	-	26472758	Jiyoye	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.9338615363291936	[37]	[14]	-6	hSpCas9	negative selection	28944
134321837	134321860	5	+	26472758	Jiyoye	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	0.2510561795885915	[38]	[34]	2	hSpCas9	negative selection	28945
134308248	134308271	5	+	26472758	Jiyoye	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.18376804979279038	[236]	[202]	1	hSpCas9	negative selection	28946
134366501	134366524	5	-	26472758	Jiyoye	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.181408233388769	[213]	[182]	1	hSpCas9	negative selection	28947
134366477	134366500	5	-	26472758	Jiyoye	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-0.20580149538487946	[129]	[84]	-1	hSpCas9	negative selection	28948
134350325	134350348	5	-	26472758	Jiyoye	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	-0.19768667665298767	[218]	[143]	-1	hSpCas9	negative selection	28949
134319371	134319394	5	+	26472758	Jiyoye	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	-1.0683359767992857	[202]	[72]	-6	hSpCas9	negative selection	28950
134308225	134308248	5	-	26472758	KBM7	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	-0.01327539342260775	[287,233]	[169,76]	0	hSpCas9	negative selection	220059
134308354	134308377	5	-	26472758	KBM7	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.477967291995415	[1082,698]	[441,690]	5	hSpCas9	negative selection	220060
134359908	134359931	5	+	26472758	KBM7	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.666894074957461	[303,365]	[278,230]	7	hSpCas9	negative selection	220061
134321860	134321883	5	-	26472758	KBM7	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.4257965370853831	[109,98]	[75,56]	4	hSpCas9	negative selection	220062
134321837	134321860	5	+	26472758	KBM7	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	1.1228134029215264	[299,237]	[423,138]	9	hSpCas9	negative selection	220063
134308248	134308271	5	+	26472758	KBM7	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	-0.08996219611942546	[656,761]	[414,229]	-1	hSpCas9	negative selection	220064
134366501	134366524	5	-	26472758	KBM7	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.7691759274776789	[900,652]	[605,623]	8	hSpCas9	negative selection	220065
134366477	134366500	5	-	26472758	KBM7	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-0.4428458589785311	[301,135]	[97,50]	-4	hSpCas9	negative selection	220066
134350325	134350348	5	-	26472758	KBM7	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	-0.06391891547295969	[807,875]	[284,468]	0	hSpCas9	negative selection	220067
134319371	134319394	5	+	26472758	KBM7	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.0043204481780778625	[628,547]	[315,241]	0	hSpCas9	negative selection	220068
134308225	134308248	5	-	26472758	Raji	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	1.2542249237028704	[111]	[61]	9	hSpCas9	negative selection	411177
134308354	134308377	5	-	26472758	Raji	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	-0.08526154256879659	[543]	[118]	0	hSpCas9	negative selection	411178
134359908	134359931	5	+	26472758	Raji	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.5537852055617785	[181]	[61]	5	hSpCas9	negative selection	411179
134321860	134321883	5	-	26472758	Raji	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	1.770348548096029	[23]	[18]	9	hSpCas9	negative selection	411180
134321837	134321860	5	+	26472758	Raji	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-1.4704895405612373	[202]	[16]	-7	hSpCas9	negative selection	411181
134308248	134308271	5	+	26472758	Raji	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.45403405967219324	[323]	[102]	4	hSpCas9	negative selection	411182
134366501	134366524	5	-	26472758	Raji	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.6204531176129701	[383]	[136]	6	hSpCas9	negative selection	411183
134366477	134366500	5	-	26472758	Raji	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-0.9865926128354141	[110]	[12]	-6	hSpCas9	negative selection	411184
134350325	134350348	5	-	26472758	Raji	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	-0.09987761734168554	[410]	[88]	-1	hSpCas9	negative selection	411185
134319371	134319394	5	+	26472758	Raji	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	-0.12143515512228131	[374]	[79]	-1	hSpCas9	negative selection	411186
134308225	134308248	5	-	26472758	K562	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.6221486142221608	[283]	[368]	5	hSpCas9	negative selection	602295
134308354	134308377	5	-	26472758	K562	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.4855623233000326	[818]	[967]	4	hSpCas9	negative selection	602296
134359908	134359931	5	+	26472758	K562	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	1.1662471135093346	[236]	[448]	8	hSpCas9	negative selection	602297
134321860	134321883	5	-	26472758	K562	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-3.147898695112313	[104]	[9]	-8	hSpCas9	negative selection	602298
134321837	134321860	5	+	26472758	K562	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-1.0331152478624621	[239]	[98]	-5	hSpCas9	negative selection	602299
134308248	134308271	5	+	26472758	K562	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.029646586807275555	[534]	[460]	0	hSpCas9	negative selection	602300
134366501	134366524	5	-	26472758	K562	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.8204329925118748	[592]	[883]	6	hSpCas9	negative selection	602301
134366477	134366500	5	-	26472758	K562	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.9099996885958876	[144]	[229]	7	hSpCas9	negative selection	602302
134350325	134350348	5	-	26472758	K562	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.6222233207463154	[470]	[611]	5	hSpCas9	negative selection	602303
134319371	134319394	5	+	26472758	K562	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	-0.1785529531546141	[546]	[407]	-1	hSpCas9	negative selection	602304
134298688	134298711	5	-	26627737	DLD1	viability	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	0.6166160190249975	[193]	[79,114,85]	6	hSpCas9	negative selection	826862
134308125	134308148	5	+	26627737	DLD1	viability	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.17523264783107206	[659]	[160,463,103]	1	hSpCas9	negative selection	826863
134308346	134308369	5	-	26627737	DLD1	viability	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.17971613327325442	[515]	[129,80,203]	-2	hSpCas9	negative selection	826864
134312340	134312363	5	+	26627737	DLD1	viability	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	1.271327269087986	[232]	[185,147,189]	9	hSpCas9	negative selection	826865
134298688	134298711	5	-	26627737	GBM cells	viability after 5 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.44212304294938143	[75]	[37,21]	-6	hSpCas9	negative selection	909177
134308125	134308148	5	+	26627737	GBM cells	viability after 5 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.20542278492904986	[386]	[177,181]	-3	hSpCas9	negative selection	909178
134308346	134308369	5	-	26627737	GBM cells	viability after 5 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.9236969758155735	[201]	[232,177]	9	hSpCas9	negative selection	909179
134312340	134312363	5	+	26627737	GBM cells	viability after 5 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.11651616568392031	[187]	[68,116]	-2	hSpCas9	negative selection	909180
134298688	134298711	5	-	26627737	GBM cells	viability after 13 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	0.13963692451216025	[75]	[72,22]	1	hSpCas9	negative selection	991492
134308125	134308148	5	+	26627737	GBM cells	viability after 13 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.07376792579267843	[386]	[279,172]	0	hSpCas9	negative selection	991493
134308346	134308369	5	-	26627737	GBM cells	viability after 13 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.9361657454008593	[201]	[260,167]	9	hSpCas9	negative selection	991494
134312340	134312363	5	+	26627737	GBM cells	viability after 13 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.10576009628998428	[187]	[96,92]	-1	hSpCas9	negative selection	991495
134298688	134298711	5	-	26627737	GBM cells	viability after 21 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-2.682127772168365	[75]	[7,4]	-9	hSpCas9	negative selection	1073807
134308125	134308148	5	+	26627737	GBM cells	viability after 21 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.6295548106487231	[386]	[149,122]	-5	hSpCas9	negative selection	1073808
134308346	134308369	5	-	26627737	GBM cells	viability after 21 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.0007046003163933556	[201]	[116,102]	0	hSpCas9	negative selection	1073809
134312340	134312363	5	+	26627737	GBM cells	viability after 21 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.25900725490773063	[187]	[116,126]	2	hSpCas9	negative selection	1073810
134298688	134298711	5	-	26627737	RPE1	viability after 9 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-3.169941047655623	[693]	[31,13]	-9	hSpCas9	negative selection	1156122
134308125	134308148	5	+	26627737	RPE1	viability after 9 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.8445176821693137	[893]	[633,332]	5	hSpCas9	negative selection	1156123
134308346	134308369	5	-	26627737	RPE1	viability after 9 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.26185963434911186	[690]	[234,109]	-2	hSpCas9	negative selection	1156124
134312340	134312363	5	+	26627737	RPE1	viability after 9 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.5396528707408264	[150]	[42,18]	-4	hSpCas9	negative selection	1156125
134298688	134298711	5	-	26627737	RPE1	viability after 12 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-5.957717940183968	[693]	[2,2]	-9	hSpCas9	negative selection	1238437
134308125	134308148	5	+	26627737	RPE1	viability after 12 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.6880636314404953	[893]	[555,207]	4	hSpCas9	negative selection	1238438
134308346	134308369	5	-	26627737	RPE1	viability after 12 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.022533737734538678	[690]	[157,208]	0	hSpCas9	negative selection	1238439
134312340	134312363	5	+	26627737	RPE1	viability after 12 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	1.12833649759022	[150]	[111,63]	6	hSpCas9	negative selection	1238440
134298688	134298711	5	-	26627737	RPE1	viability after 15 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-7.617042978706367	[693]	[0,0]	-9	hSpCas9	negative selection	1320752
134308125	134308148	5	+	26627737	RPE1	viability after 15 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.5570574120418899	[893]	[592,158]	3	hSpCas9	negative selection	1320753
134308346	134308369	5	-	26627737	RPE1	viability after 15 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.017689627664418284	[690]	[288,109]	0	hSpCas9	negative selection	1320754
134312340	134312363	5	+	26627737	RPE1	viability after 15 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.6583694569724283	[150]	[43,89]	4	hSpCas9	negative selection	1320755
134298688	134298711	5	-	26627737	RPE1	viability after 18 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-7.549123592477518	[693]	[0,0]	-9	hSpCas9	negative selection	1403067
134308125	134308148	5	+	26627737	RPE1	viability after 18 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.7166366925907184	[893]	[526,256]	4	hSpCas9	negative selection	1403068
134308346	134308369	5	-	26627737	RPE1	viability after 18 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.5327259035539106	[690]	[335,198]	3	hSpCas9	negative selection	1403069
134312340	134312363	5	+	26627737	RPE1	viability after 18 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	1.2161444379966906	[150]	[55,135]	7	hSpCas9	negative selection	1403070
134298688	134298711	5	-	26627737	HeLa	viability after 8 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-1.320105328231239	[156]	[69,1,19]	-8	hSpCas9	negative selection	1485382
134308125	134308148	5	+	26627737	HeLa	viability after 8 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.48668792068204275	[636]	[233,133,230]	-5	hSpCas9	negative selection	1485383
134308346	134308369	5	-	26627737	HeLa	viability after 8 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.3243369933967659	[505]	[568,200,131]	3	hSpCas9	negative selection	1485384
134312340	134312363	5	+	26627737	HeLa	viability after 8 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.07093966126065876	[285]	[296,12,86]	0	hSpCas9	negative selection	1485385
134298688	134298711	5	-	26627737	HeLa	viability after 12 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-1.5066923805707648	[156]	[0,30,34]	-8	hSpCas9	negative selection	1567697
134308125	134308148	5	+	26627737	HeLa	viability after 12 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.030989051511362553	[636]	[331,239,204]	0	hSpCas9	negative selection	1567698
134308346	134308369	5	-	26627737	HeLa	viability after 12 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.2223181492094477	[505]	[241,127,174]	-2	hSpCas9	negative selection	1567699
134312340	134312363	5	+	26627737	HeLa	viability after 12 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.5041096825144946	[285]	[69,126,47]	-4	hSpCas9	negative selection	1567700
134298688	134298711	5	-	26627737	HeLa	viability after 15 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.3980104543061045	[156]	[116,22,0]	-3	hSpCas9	negative selection	1650012
134308125	134308148	5	+	26627737	HeLa	viability after 15 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.452724031503451	[636]	[188,146,235]	-4	hSpCas9	negative selection	1650013
134308346	134308369	5	-	26627737	HeLa	viability after 15 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.2030509849194335	[505]	[203,171,158]	-2	hSpCas9	negative selection	1650014
134312340	134312363	5	+	26627737	HeLa	viability after 15 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.3257470876954106	[285]	[64,145,65]	-3	hSpCas9	negative selection	1650015
134298688	134298711	5	-	26627737	HeLa	viability after 18 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.2797335018967373	[156]	[84,20,0]	-2	hSpCas9	negative selection	1732327
134308125	134308148	5	+	26627737	HeLa	viability after 18 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.5118056732499663	[636]	[118,112,235]	-4	hSpCas9	negative selection	1732328
134308346	134308369	5	-	26627737	HeLa	viability after 18 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.24345730961123468	[505]	[121,148,158]	-2	hSpCas9	negative selection	1732329
134312340	134312363	5	+	26627737	HeLa	viability after 18 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.3574392853945755	[285]	[45,112,65]	-3	hSpCas9	negative selection	1732330
134298688	134298711	5	-	26627737	HCT116	viability after 6 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.9523929805994668	[401]	[80,5]	-5	hSpCas9	negative selection	1814642
134308125	134308148	5	+	26627737	HCT116	viability after 6 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.6027599350580473	[866]	[293,158]	3	hSpCas9	negative selection	1814643
134308346	134308369	5	-	26627737	HCT116	viability after 6 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.4260476029875587	[488]	[130,87]	2	hSpCas9	negative selection	1814644
134312340	134312363	5	+	26627737	HCT116	viability after 6 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.3723067030538625	[269]	[84,3]	-2	hSpCas9	negative selection	1814645
134298688	134298711	5	-	26627737	HCT116	viability after 8 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-2.0786404658676054	[283]	[71,21,17]	-9	hSpCas9	negative selection	1896957
134308125	134308148	5	+	26627737	HCT116	viability after 8 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.3400917660975756	[388]	[280,59,168]	-4	hSpCas9	negative selection	1896958
134308346	134308369	5	-	26627737	HCT116	viability after 8 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.2023937788230501	[353]	[248,219,204]	2	hSpCas9	negative selection	1896959
134312340	134312363	5	+	26627737	HCT116	viability after 8 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.4405011260916836	[159]	[141,69,146]	4	hSpCas9	negative selection	1896960
134298688	134298711	5	-	26627737	HCT116	viability after 9 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-1.3340738322017192	[401]	[17,61]	-7	hSpCas9	negative selection	1979272
134308125	134308148	5	+	26627737	HCT116	viability after 9 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.48377909684054843	[866]	[207,131]	-3	hSpCas9	negative selection	1979273
134308346	134308369	5	-	26627737	HCT116	viability after 9 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	1.4461561018966338	[488]	[271,421]	8	hSpCas9	negative selection	1979274
134312340	134312363	5	+	26627737	HCT116	viability after 9 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.6021895411199917	[269]	[47,157]	4	hSpCas9	negative selection	1979275
134298688	134298711	5	-	26627737	HCT116	viability after 12 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-4.158076036926377	[283]	[9,10,3]	-9	hSpCas9	negative selection	2061587
134308125	134308148	5	+	26627737	HCT116	viability after 12 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.00914998621808294	[388]	[320,202,82]	0	hSpCas9	negative selection	2061588
134308346	134308369	5	-	26627737	HCT116	viability after 12 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.1641064822877163	[353]	[178,169,277]	1	hSpCas9	negative selection	2061589
134312340	134312363	5	+	26627737	HCT116	viability after 12 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.784959436230843	[159]	[109,156,170]	7	hSpCas9	negative selection	2061590
134298688	134298711	5	-	26627737	HCT116	viability after 15 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-2.9132378950568896	[283]	[36,22,6]	-9	hSpCas9	negative selection	2143902
134308125	134308148	5	+	26627737	HCT116	viability after 15 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.0269682431941074	[388]	[144,221,280]	0	hSpCas9	negative selection	2143903
134308346	134308369	5	-	26627737	HCT116	viability after 15 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.35597273494065934	[353]	[206,214,350]	3	hSpCas9	negative selection	2143904
134312340	134312363	5	+	26627737	HCT116	viability after 15 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.9363501054032201	[159]	[114,135,267]	7	hSpCas9	negative selection	2143905
134298688	134298711	5	-	26627737	HCT116	viability after 18 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-1.8329021176388933	[283]	[11,88,9]	-9	hSpCas9	negative selection	2226217
134308125	134308148	5	+	26627737	HCT116	viability after 18 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.5002978234455363	[388]	[114,121,163]	-4	hSpCas9	negative selection	2226218
134308346	134308369	5	-	26627737	HCT116	viability after 18 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.14534073392666197	[353]	[185,77,316]	1	hSpCas9	negative selection	2226219
134312340	134312363	5	+	26627737	HCT116	viability after 18 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.3950059266411651	[159]	[75,44,191]	3	hSpCas9	negative selection	2226220
134359914	134359937	5	+	24336569	HL60	viability	AGTCAATTGCTCGAAGGATCTGG	CDKL3	ENSG00000006837	0.25950813831347025	[586]	[1486]	2	hSpCas9	negative selection	2256799
134359920	134359943	5	+	24336569	HL60	viability	TTGCTCGAAGGATCTGGAAGAGG	CDKL3	ENSG00000006837	-0.5774374446416644	[1166]	[1654]	-5	hSpCas9	negative selection	2256800
134359970	134359993	5	-	24336569	HL60	viability	GAGTTACAACATTATTGTCATGG	CDKL3	ENSG00000006837	0.6235291037990298	[437]	[1427]	5	hSpCas9	negative selection	2256801
134359986	134360009	5	+	24336569	HL60	viability	GTAACTCATCTAATACTGTGTGG	CDKL3	ENSG00000006837	0.724918327262535	[847]	[2965]	6	hSpCas9	negative selection	2256802
134360052	134360075	5	+	24336569	HL60	viability	AAACTTCAATCAGATTGACCAGG	CDKL3	ENSG00000006837	0.08176076154909517	[1222]	[2738]	0	hSpCas9	negative selection	2256803
134366358	134366381	5	-	24336569	HL60	viability	GAGAGAAATAAAGTTTCTAAAGG	CDKL3	ENSG00000006837	0.495058037291607	[399]	[1192]	4	hSpCas9	negative selection	2256804
134366433	134366456	5	-	24336569	HL60	viability	TAAGAATACTGGGCAGATAGTGG	CDKL3	ENSG00000006837	-0.2044002067598878	[201]	[370]	-2	hSpCas9	negative selection	2256805
134366443	134366466	5	-	24336569	HL60	viability	AATGTAAACATAAGAATACTGGG	CDKL3	ENSG00000006837	0.1393045782278876	[634]	[1479]	1	hSpCas9	negative selection	2256806
134366477	134366500	5	-	24336569	HL60	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-0.5498386572534533	[798]	[1154]	-5	hSpCas9	negative selection	2256807
134366501	134366524	5	-	24336569	HL60	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.10442068828591144	[868]	[1976]	1	hSpCas9	negative selection	2256808
134359914	134359937	5	+	24336569	KBM7	viability	AGTCAATTGCTCGAAGGATCTGG	CDKL3	ENSG00000006837	0.03217240646801067	[563]	[1572]	0	hSpCas9	negative selection	2323976
134359920	134359943	5	+	24336569	KBM7	viability	TTGCTCGAAGGATCTGGAAGAGG	CDKL3	ENSG00000006837	0.13255938504392606	[698]	[2089]	1	hSpCas9	negative selection	2323977
134359970	134359993	5	-	24336569	KBM7	viability	GAGTTACAACATTATTGTCATGG	CDKL3	ENSG00000006837	0.5286688300177709	[443]	[1746]	5	hSpCas9	negative selection	2323978
134359986	134360009	5	+	24336569	KBM7	viability	GTAACTCATCTAATACTGTGTGG	CDKL3	ENSG00000006837	0.2889005599158512	[890]	[2968]	2	hSpCas9	negative selection	2323979
134360052	134360075	5	+	24336569	KBM7	viability	AAACTTCAATCAGATTGACCAGG	CDKL3	ENSG00000006837	0.20765926166238047	[807]	[2544]	2	hSpCas9	negative selection	2323980
134366358	134366381	5	-	24336569	KBM7	viability	GAGAGAAATAAAGTTTCTAAAGG	CDKL3	ENSG00000006837	1.067266499980497	[396]	[2268]	8	hSpCas9	negative selection	2323981
134366433	134366456	5	-	24336569	KBM7	viability	TAAGAATACTGGGCAGATAGTGG	CDKL3	ENSG00000006837	1.4259913258596097	[72]	[534]	9	hSpCas9	negative selection	2323982
134366443	134366466	5	-	24336569	KBM7	viability	AATGTAAACATAAGAATACTGGG	CDKL3	ENSG00000006837	0.0768743209996146	[421]	[1213]	0	hSpCas9	negative selection	2323983
134366477	134366500	5	-	24336569	KBM7	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-0.8295072811724108	[760]	[1167]	-6	hSpCas9	negative selection	2323984
134366501	134366524	5	-	24336569	KBM7	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.834622620022869	[485]	[2363]	7	hSpCas9	negative selection	2323985
134342473	134342496	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTGTAGTCCCAGCTACTCGGG	CDKL3	ENSG00000006837	-0.8391819250206091	[111,80]	[9,12]	-5	dCas9-VP64	positive selection	2393377
134367151	134367174	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTAGAACGCAGCAACTCCGCCGG	CDKL3	ENSG00000006837	1.395870139370202	[59,35]	[34,19]	5	dCas9-VP64	positive selection	2396987
134367228	134367251	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGAAACGGAAACCTACTCTGG	CDKL3	ENSG00000006837	1.091234629371096	[44,120]	[58,16]	4	dCas9-VP64	positive selection	2396988
134367176	134367199	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGTGCGCAAGACCGGAACATGG	CDKL3	ENSG00000006837	3.081490935869319	[41,162]	[57,339]	8	dCas9-VP64	positive selection	2396989
134293602	134293625	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTTGCTATGTTGCCCCAG	CDKL3	ENSG00000006837	0.7258925451918798	[40,76]	[27,13]	3	dCas9-VP64	positive selection	2423514
134371044	134371067	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAACGCGTCATAGGGACACGTGG	CDKL3	ENSG00000006837	0.49217220863700695	[52,15]	[2,18]	2	dCas9-VP64	positive selection	2432414
134370997	134371020	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTGGCTGAAACTCACATCCAGG	CDKL3	ENSG00000006837	0.07724778787647993	[132,38]	[30,6]	0	dCas9-VP64	positive selection	2432415
134371015	134371038	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCACGTGAGCGCCTCGCCTGG	CDKL3	ENSG00000006837	-3.3788759293884993	[13,270]	[2,2]	-9	dCas9-VP64	positive selection	2432416
134295934	134295957	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAGTGG	CDKL3	ENSG00000006837	0.9977856233970179	[9,4]	[4,0]	4	dCas9-VP64	positive selection	2435982
134362893	134362916	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCGACAGACAG	CDKL3	ENSG00000006837	1.2012671036636573	[14,1]	[1,5]	5	dCas9-VP64	positive selection	2454939
134293276	134293299	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAAATGCTGGGATTACAGG	CDKL3	ENSG00000006837	0.20161513672590614	[46,60]	[10,15]	1	dCas9-VP64	positive selection	2475393
134342473	134342496	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTGTAGTCCCAGCTACTCGGG	CDKL3	ENSG00000006837	1.1377968629765447	[99,72]	[76,47]	7	dCas9-VP64	positive selection	2488632
134367151	134367174	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTAGAACGCAGCAACTCCGCCGG	CDKL3	ENSG00000006837	0.5351163859138454	[175,46]	[30,73]	4	dCas9-VP64	positive selection	2492242
134367228	134367251	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGAAACGGAAACCTACTCTGG	CDKL3	ENSG00000006837	-0.4980458550045658	[67,81]	[17,15]	-5	dCas9-VP64	positive selection	2492243
134367176	134367199	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGTGCGCAAGACCGGAACATGG	CDKL3	ENSG00000006837	0.35018967294297965	[91,265]	[120,28]	3	dCas9-VP64	positive selection	2492244
134293602	134293625	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTTGCTATGTTGCCCCAG	CDKL3	ENSG00000006837	-0.28323094604648114	[112,110]	[38,20]	-3	dCas9-VP64	positive selection	2518769
134371044	134371067	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAACGCGTCATAGGGACACGTGG	CDKL3	ENSG00000006837	-0.3750230773219452	[185,292]	[56,61]	-4	dCas9-VP64	positive selection	2527669
134370997	134371020	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTGGCTGAAACTCACATCCAGG	CDKL3	ENSG00000006837	0.16050439279700338	[43,151]	[11,56]	1	dCas9-VP64	positive selection	2527670
134371015	134371038	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCACGTGAGCGCCTCGCCTGG	CDKL3	ENSG00000006837	-0.9212773674684264	[133,671]	[22,110]	-8	dCas9-VP64	positive selection	2527671
134295934	134295957	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAGTGG	CDKL3	ENSG00000006837	-0.1814090993543942	[50,40]	[18,6]	-2	dCas9-VP64	positive selection	2531237
134362893	134362916	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCGACAGACAG	CDKL3	ENSG00000006837	0.32779538109836626	[14,14]	[4,6]	2	dCas9-VP64	positive selection	2550194
134293276	134293299	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAAATGCTGGGATTACAGG	CDKL3	ENSG00000006837	-0.42275240861415275	[53,301]	[32,50]	-4	dCas9-VP64	positive selection	2570648
134321838	134321861	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-0.41617751715910495	[2,2]	[1,1]	-5	hSpCas9	positive selection	2978245
134360070	134360093	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.4353970100787866	[5,5]	[5,6]	8	hSpCas9	positive selection	2978246
134350310	134350333	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	-0.1169570160400211	[4,4]	[3,3]	-2	hSpCas9	positive selection	2978247
134366411	134366434	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCTCATAAAATATCTTAATGG	CDKL3	ENSG00000006837	-0.45432202057469984	[2,1]	[2,0]	-6	hSpCas9	positive selection	2978248
134321838	134321861	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	0.3021360534325498	[2,2]	[1,2]	5	hSpCas9	positive selection	3046103
134360070	134360093	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.4395350594695885	[5,5]	[5,5]	7	hSpCas9	positive selection	3046104
134350310	134350333	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.520588139249152	[4,4]	[4,5]	8	hSpCas9	positive selection	3046105
134366411	134366434	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCTCATAAAATATCTTAATGG	CDKL3	ENSG00000006837	-0.6071660273402695	[2,2]	[1,0]	-8	hSpCas9	positive selection	3046106
134306655	134306678		-	24336571	A375	resistance to PLX after 7 days	CGCACTTCTTCACAATCTATTGG	CDKL3	ENSG00000006837	-0.11204667621582437	[14,14]	[12,14]	-3	hSpCas9	positive selection	3104667
134359908	134359931		+	24336571	A375	resistance to PLX after 7 days	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.19130310743190831	[7,8]	[7,10]	6	hSpCas9	positive selection	3104668
134321860	134321883		-	24336571	A375	resistance to PLX after 7 days	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.07064785958108111	[8,7]	[6,8]	-2	hSpCas9	positive selection	3104669
134321888	134321911		-	24336571	A375	resistance to PLX after 7 days	GTTTCAGACCTGTGGATATCTGG	CDKL3	ENSG00000006837	0.11358476686406593	[30,28]	[34,30]	4	hSpCas9	positive selection	3104670
134306626	134306649		-	24336571	A375	resistance to PLX after 7 days	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.28891431978536825	[10,11]	[13,13]	7	hSpCas9	positive selection	3104671
134306655	134306678		-	24336571	A375	resistance to PLX after 14 days	CGCACTTCTTCACAATCTATTGG	CDKL3	ENSG00000006837	-1.0633061217200663	[16,9]	[2,1]	-9	hSpCas9	positive selection	3162460
134359908	134359931		+	24336571	A375	resistance to PLX after 14 days	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	1.1534475724204716	[10,10]	[10,11]	8	hSpCas9	positive selection	3162461
134321860	134321883		-	24336571	A375	resistance to PLX after 14 days	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.01383517736513562	[8,8]	[3,3]	0	hSpCas9	positive selection	3162462
134321888	134321911		-	24336571	A375	resistance to PLX after 14 days	GTTTCAGACCTGTGGATATCTGG	CDKL3	ENSG00000006837	0.008798731344434874	[26,25]	[10,12]	0	hSpCas9	positive selection	3162463
134306626	134306649		-	24336571	A375	resistance to PLX after 14 days	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.21395644648004958	[14,17]	[9,6]	2	hSpCas9	positive selection	3162464
134306655	134306678		-	24336571	A375	viability after 7 days	CGCACTTCTTCACAATCTATTGG	CDKL3	ENSG00000006837	-0.6572531732858473	[24]	[14,14]	-7	hSpCas9	negative selection	3220253
134359908	134359931		+	24336571	A375	viability after 7 days	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-0.013564112735284128	[8]	[7,8]	0	hSpCas9	negative selection	3220254
134321860	134321883		-	24336571	A375	viability after 7 days	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.745928782037502	[14]	[8,7]	-8	hSpCas9	negative selection	3220255
134321888	134321911		-	24336571	A375	viability after 7 days	GTTTCAGACCTGTGGATATCTGG	CDKL3	ENSG00000006837	0.4477952737829357	[22]	[30,28]	6	hSpCas9	negative selection	3220256
134306626	134306649		-	24336571	A375	viability after 7 days	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.196098780287765	[10]	[10,11]	3	hSpCas9	negative selection	3220257
134306655	134306678		-	24336571	A375	viability after 14 days	CGCACTTCTTCACAATCTATTGG	CDKL3	ENSG00000006837	-0.7994524410391375	[24]	[16,9]	-7	hSpCas9	negative selection	3278046
134359908	134359931		+	24336571	A375	viability after 14 days	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.391088442029232	[8]	[10,10]	5	hSpCas9	negative selection	3278047
134321860	134321883		-	24336571	A375	viability after 14 days	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.6260512704686834	[14]	[8,8]	-6	hSpCas9	negative selection	3278048
134321888	134321911		-	24336571	A375	viability after 14 days	GTTTCAGACCTGTGGATATCTGG	CDKL3	ENSG00000006837	0.287277701735115	[22]	[26,25]	4	hSpCas9	negative selection	3278049
134306626	134306649		-	24336571	A375	viability after 14 days	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.7306459209979215	[10]	[14,17]	8	hSpCas9	negative selection	3278050
134306601	134306624	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-1.155278225477911	[303,377]	[0,0]	-7	hSpCas9	positive selection	3342453
134321860	134321883	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.9534261089736579	[79,77]	[0,0]	4	hSpCas9	positive selection	3342454
134306626	134306649	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.6501409723648456	[95,98]	[0,0]	3	hSpCas9	positive selection	3342455
134321821	134321844	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	1.1698633701954957	[67,67]	[0,0]	5	hSpCas9	positive selection	3361687
134304513	134304536	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	0.1280431945008686	[139,139]	[0,0]	0	hSpCas9	positive selection	3361688
134304543	134304566	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	-1.9496881087316973	[590,590]	[0,0]	-9	hSpCas9	positive selection	3361689
134321837	134321860	5	+	26780180	HT29	viability (Avana library 4 designs)	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	2.76562660642862	[]	[]	8	hSpCas9	negative selection	3414558
134360070	134360093	5	-	26780180	HT29	viability (Avana library 4 designs)	GCAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-0.244080125031884	[]	[]	-4	hSpCas9	negative selection	3414559
134350309	134350332	5	+	26780180	HT29	viability (Avana library 4 designs)	TAGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.540561231352785	[]	[]	2	hSpCas9	negative selection	3414560
134366410	134366433	5	+	26780180	HT29	viability (Avana library 4 designs)	TCTCTCATAAAATATCTTAATGG	CDKL3	ENSG00000006837	0.311800730048162	[]	[]	1	hSpCas9	negative selection	3414561
134321837	134321860	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-5.95791526646506	[]	[]	-6	hSpCas9	negative selection	3491134
134350309	134350332	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	-2.90415551816037	[]	[]	-3	hSpCas9	negative selection	3491135
134366410	134366433	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCTCATAAAATATCTTAATGG	CDKL3	ENSG00000006837	-21.0810436332442	[]	[]	-9	hSpCas9	negative selection	3491136
134360070	134360093	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-3.55509854150374	[]	[]	-4	hSpCas9	negative selection	3491137
134359908	134359931	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-1.61820791132088	[]	[]	-2	hSpCas9	negative selection	3491138
134359986	134360009	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAACTCATCTAATACTGTGTGG	CDKL3	ENSG00000006837	-5.72280346377822	[]	[]	-6	hSpCas9	negative selection	3491139
134321837	134321860	5	+	26780180	A375	viability (Avana lentiGuide)	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	3.92288430497753	[]	[]	4	hSpCas9	negative selection	3599793
134350309	134350332	5	+	26780180	A375	viability (Avana lentiGuide)	TAGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	3.74206721209458	[]	[]	3	hSpCas9	negative selection	3599794
134366410	134366433	5	+	26780180	A375	viability (Avana lentiGuide)	TCTCTCATAAAATATCTTAATGG	CDKL3	ENSG00000006837	8.66189830900562	[]	[]	6	hSpCas9	negative selection	3599795
134360070	134360093	5	-	26780180	A375	viability (Avana lentiGuide)	GCAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-0.651541406688456	[]	[]	-1	hSpCas9	negative selection	3599796
134359908	134359931	5	+	26780180	A375	viability (Avana lentiGuide)	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-1.01712465806663	[]	[]	-1	hSpCas9	negative selection	3599797
134359986	134360009	5	+	26780180	A375	viability (Avana lentiGuide)	GTAACTCATCTAATACTGTGTGG	CDKL3	ENSG00000006837	-1.1255389332463	[]	[]	-2	hSpCas9	negative selection	3599798
134321837	134321860	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-0.5638374230588882	[4]	[3,1]	-7	hSpCas9	positive selection	3708452
134350309	134350332	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	-0.25550078480220073	[6]	[4,4]	-4	hSpCas9	positive selection	3708453
134366410	134366433	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCTCATAAAATATCTTAATGG	CDKL3	ENSG00000006837	-2.3013394348447083	[6]	[0,0]	-9	hSpCas9	positive selection	3708454
134360070	134360093	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-0.16818864593161678	[5]	[5,4]	-3	hSpCas9	positive selection	3708455
134359908	134359931	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.07123307173501882	[5]	[5,5]	1	hSpCas9	positive selection	3708456
134359986	134360009	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAACTCATCTAATACTGTGTGG	CDKL3	ENSG00000006837	-0.3628376243641858	[6]	[4,4]	-5	hSpCas9	positive selection	3708457
134321837	134321860	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-0.35541350593522425	[4]	[2,3]	-5	hSpCas9	positive selection	3817059
134350309	134350332	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	-0.17936349744556052	[6]	[4,4]	-2	hSpCas9	positive selection	3817060
134366410	134366433	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCTCATAAAATATCTTAATGG	CDKL3	ENSG00000006837	-0.0916440424390706	[3]	[2,3]	-1	hSpCas9	positive selection	3817061
134360070	134360093	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.234636726678371	[7]	[7,6]	6	hSpCas9	positive selection	3817062
134359908	134359931	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.16040461544909576	[5]	[4,5]	4	hSpCas9	positive selection	3817063
134359986	134360009	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAACTCATCTAATACTGTGTGG	CDKL3	ENSG00000006837	0.10906813666417545	[5]	[4,5]	2	hSpCas9	positive selection	3817064
134304513	134304536	5	-	26780180	A375	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	0.871480131918093	[]	[]	3	hSpCas9	negative selection	3925241
134321860	134321883	5	-	26780180	A375	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	1.1602176212706	[]	[]	6	hSpCas9	negative selection	3925242
134304543	134304566	5	+	26780180	A375	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.792537308319791	[]	[]	3	hSpCas9	negative selection	3925243
134306626	134306649	5	-	26780180	A375	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.84156602330808	[]	[]	3	hSpCas9	negative selection	3925244
134321821	134321844	5	-	26780180	A375	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.909718600872466	[]	[]	4	hSpCas9	negative selection	3925245
134306601	134306624	5	+	26780180	A375	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	1.74398979428418	[]	[]	9	hSpCas9	negative selection	3925246
134304513	134304536	5	-	26780180	HT29	viability (GeCKOv2 library)	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	1.15690504689368	[]	[]	5	hSpCas9	negative selection	4033207
134321860	134321883	5	-	26780180	HT29	viability (GeCKOv2 library)	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	1.55717751683508	[]	[]	7	hSpCas9	negative selection	4033208
134304543	134304566	5	+	26780180	HT29	viability (GeCKOv2 library)	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.701699918769604	[]	[]	2	hSpCas9	negative selection	4033209
134306626	134306649	5	-	26780180	HT29	viability (GeCKOv2 library)	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	1.20319797490012	[]	[]	6	hSpCas9	negative selection	4033210
134321821	134321844	5	-	26780180	HT29	viability (GeCKOv2 library)	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.473800570062271	[]	[]	1	hSpCas9	negative selection	4033211
134306601	134306624	5	+	26780180	HT29	viability (GeCKOv2 library)	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	1.52421204093307	[]	[]	7	hSpCas9	negative selection	4033212
134306655	134306678	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCACTTCTTCACAATCTATTGG	CDKL3	ENSG00000006837	-0.25635350233082416	[3]	[2,1]	-6	hSpCas9	positive selection	4126696
134359908	134359931	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.2781100284950402	[3]	[2,3]	7	hSpCas9	positive selection	4126697
134321860	134321883	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.06395392040682993	[3]	[1,1]	-1	hSpCas9	positive selection	4126698
134321888	134321911	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTTCAGACCTGTGGATATCTGG	CDKL3	ENSG00000006837	0.13627305614634072	[4]	[3,3]	3	hSpCas9	positive selection	4126699
134306626	134306649	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.0011127004593212923	[3]	[1,3]	0	hSpCas9	positive selection	4126700
134306655	134306678	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCACTTCTTCACAATCTATTGG	CDKL3	ENSG00000006837	0.46927954625444834	[4]	[5,4,4,0]	3	hSpCas9	positive selection	4190718
134359908	134359931	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-0.39012998139162036	[3]	[1,0,0,0]	-6	hSpCas9	positive selection	4190719
134321860	134321883	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.11974681738920706	[2]	[0,0,4,0]	0	hSpCas9	positive selection	4190720
134321888	134321911	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTTCAGACCTGTGGATATCTGG	CDKL3	ENSG00000006837	1.1784690938272788	[4]	[4,3,3,4]	8	hSpCas9	positive selection	4190721
134306626	134306649	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.012644434747297428	[3]	[3,0,2,0]	0	hSpCas9	positive selection	4190722
134306601	134306624	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	0.14629670251359495	[4]	[2,3]	3	hSpCas9	positive selection	4262509
134321860	134321883	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.24211899179732266	[2]	[0,1]	-5	hSpCas9	positive selection	4262510
134306626	134306649	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.05193213992540707	[2]	[2,1]	1	hSpCas9	positive selection	4262511
134321821	134321844	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.6533595594546083	[1]	[1,3]	9	hSpCas9	positive selection	4326787
134304513	134304536	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.00039458326414343325	[2]	[2,1]	0	hSpCas9	positive selection	4326788
134304543	134304566	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.28971111424844204	[4]	[4,3]	6	hSpCas9	positive selection	4326789
134359909	134359931	5	+	27760321	OCIAML3	viability	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-5.259073683405567	[57,40]	[0,0]	-9	hSpCas9	negative selection	4388131
134360070	134360092	5	-	27760321	OCIAML3	viability	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-0.37881028075760736	[302,279]	[114,253]	-4	hSpCas9	negative selection	4388132
134312341	134312363	5	+	27760321	OCIAML3	viability	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.6937896076389243	[367,350]	[180,164]	-6	hSpCas9	negative selection	4388133
134350310	134350332	5	+	27760321	OCIAML3	viability	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.604847816571855	[397,306]	[433,392]	7	hSpCas9	negative selection	4388134
134350365	134350387	5	+	27760321	OCIAML3	viability	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	0.11231950842853533	[225,198]	[177,180]	1	hSpCas9	negative selection	4388135
134359909	134359931	5	+	27760321	OCIAML2	viability	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-2.695187575805508	[57,40]	[9,0]	-9	hSpCas9	negative selection	4471594
134360070	134360092	5	-	27760321	OCIAML2	viability	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.17789905748242402	[302,279]	[195,359]	2	hSpCas9	negative selection	4471595
134312341	134312363	5	+	27760321	OCIAML2	viability	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.059119862408786916	[367,350]	[245,378]	0	hSpCas9	negative selection	4471596
134350310	134350332	5	+	27760321	OCIAML2	viability	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	-0.0273245098445975	[397,306]	[228,341]	0	hSpCas9	negative selection	4471597
134350365	134350387	5	+	27760321	OCIAML2	viability	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	-0.9068780080662404	[225,198]	[100,78]	-7	hSpCas9	negative selection	4471598
134359909	134359931	5	+	27760321	MV411	viability	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-5.013995114490885	[57,40]	[0,0]	-9	hSpCas9	negative selection	4555057
134360070	134360092	5	-	27760321	MV411	viability	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	1.8677174420649973	[302,279]	[1018,225]	9	hSpCas9	negative selection	4555058
134312341	134312363	5	+	27760321	MV411	viability	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	1.0041738263856705	[367,350]	[575,326]	7	hSpCas9	negative selection	4555059
134350310	134350332	5	+	27760321	MV411	viability	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.18905100571787745	[397,306]	[317,180]	1	hSpCas9	negative selection	4555060
134350365	134350387	5	+	27760321	MV411	viability	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	0.24504832388029163	[225,198]	[7,402]	1	hSpCas9	negative selection	4555061
134359909	134359931	5	+	27760321	HL60	viability	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-1.3165930880703902	[57,40]	[17,13]	-8	hSpCas9	negative selection	4638520
134360070	134360092	5	-	27760321	HL60	viability	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.10528630281540252	[302,279]	[277,232]	1	hSpCas9	negative selection	4638521
134312341	134312363	5	+	27760321	HL60	viability	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.1548504009412851	[367,350]	[251,276]	-2	hSpCas9	negative selection	4638522
134350310	134350332	5	+	27760321	HL60	viability	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	-0.14530862571536912	[397,306]	[256,259]	-2	hSpCas9	negative selection	4638523
134350365	134350387	5	+	27760321	HL60	viability	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	1.102501510498746	[225,198]	[239,511]	9	hSpCas9	negative selection	4638524
134359909	134359931	5	+	27760321	HT1080	viability	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	4.128256785475958	[40,31]	[354,143]	9	hSpCas9	negative selection	4721983
134360070	134360092	5	-	27760321	HT1080	viability	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	2.228170744351295	[279,218]	[681,228]	9	hSpCas9	negative selection	4721984
134312341	134312363	5	+	27760321	HT1080	viability	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-6.959914000702176	[350,273]	[0,0]	-9	hSpCas9	negative selection	4721985
134350310	134350332	5	+	27760321	HT1080	viability	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	1.241900633884068	[306,239]	[472,21]	6	hSpCas9	negative selection	4721986
134350365	134350387	5	+	27760321	HT1080	viability	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	0.09522948588343938	[198,154]	[102,44]	0	hSpCas9	negative selection	4721987
134359909	134359931	5	+	27760321	HT29	viability after 7 days	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.9958348081514377	[40,31]	[147,129,12]	9	hSpCas9	negative selection	4805446
134360070	134360092	5	-	27760321	HT29	viability after 7 days	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-0.2595532894642715	[279,218]	[319,221,268]	-4	hSpCas9	negative selection	4805447
134312341	134312363	5	+	27760321	HT29	viability after 7 days	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.8598360056777332	[350,273]	[230,300,135]	-8	hSpCas9	negative selection	4805448
134350310	134350332	5	+	27760321	HT29	viability after 7 days	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	-0.15504873630830646	[306,239]	[379,316,260]	-2	hSpCas9	negative selection	4805449
134350365	134350387	5	+	27760321	HT29	viability after 7 days	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	-1.075202516943663	[198,154]	[170,59,101]	-8	hSpCas9	negative selection	4805450
134359909	134359931	5	+	27760321	HT29	viability after 25 days	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-2.1983434810105216	[40,31]	[7,12,5]	-8	hSpCas9	negative selection	4888909
134360070	134360092	5	-	27760321	HT29	viability after 25 days	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.1815429753354485	[279,218]	[295,269,414]	1	hSpCas9	negative selection	4888910
134312341	134312363	5	+	27760321	HT29	viability after 25 days	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-1.018607608370627	[350,273]	[150,143,241]	-6	hSpCas9	negative selection	4888911
134350310	134350332	5	+	27760321	HT29	viability after 25 days	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.5656432481873568	[306,239]	[425,479,485]	6	hSpCas9	negative selection	4888912
134350365	134350387	5	+	27760321	HT29	viability after 25 days	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	-0.21664795072833787	[198,154]	[153,161,210]	-2	hSpCas9	negative selection	4888913
134359909	134359931	5	+	27760321	HT29	viability after 22 days	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-1.111634923211147	[40,31]	[0,46,10]	-7	hSpCas9	negative selection	4972372
134360070	134360092	5	-	27760321	HT29	viability after 22 days	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.2717686821307544	[279,218]	[214,421,411]	3	hSpCas9	negative selection	4972373
134312341	134312363	5	+	27760321	HT29	viability after 22 days	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.6806595501574617	[350,273]	[295,178,198]	-5	hSpCas9	negative selection	4972374
134350310	134350332	5	+	27760321	HT29	viability after 22 days	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.609189017511429	[306,239]	[256,412,785]	6	hSpCas9	negative selection	4972375
134350365	134350387	5	+	27760321	HT29	viability after 22 days	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	-0.4188596653207224	[198,154]	[137,222,97]	-4	hSpCas9	negative selection	4972376
134359909	134359931	5	+	27760321	HT29	viability after 19 days	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.4441686588372775	[40,31]	[8,9,142]	4	hSpCas9	negative selection	5055835
134360070	134360092	5	-	27760321	HT29	viability after 19 days	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.15215458099081391	[279,218]	[146,271,506]	1	hSpCas9	negative selection	5055836
134312341	134312363	5	+	27760321	HT29	viability after 19 days	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-1.5985846090983313	[350,273]	[186,77,96]	-7	hSpCas9	negative selection	5055837
134350310	134350332	5	+	27760321	HT29	viability after 19 days	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.5137985105018856	[306,239]	[359,507,461]	5	hSpCas9	negative selection	5055838
134350365	134350387	5	+	27760321	HT29	viability after 19 days	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	0.2478277151240782	[198,154]	[230,224,262]	2	hSpCas9	negative selection	5055839
134359909	134359931	5	+	27760321	HT29	viability after 16 days	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-0.8411841536735043	[40,31]	[2,3,59]	-6	hSpCas9	negative selection	5139298
134360070	134360092	5	-	27760321	HT29	viability after 16 days	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-0.4378041606479409	[279,218]	[286,164,174]	-4	hSpCas9	negative selection	5139299
134312341	134312363	5	+	27760321	HT29	viability after 16 days	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.8333681041460279	[350,273]	[300,177,119]	-6	hSpCas9	negative selection	5139300
134350310	134350332	5	+	27760321	HT29	viability after 16 days	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.49222149142988314	[306,239]	[459,433,399]	5	hSpCas9	negative selection	5139301
134350365	134350387	5	+	27760321	HT29	viability after 16 days	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	0.003344065985387168	[198,154]	[329,36,244]	0	hSpCas9	negative selection	5139302
134359909	134359931	5	+	27760321	HT29	viability after 13 days	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-3.192041745782845	[40,31]	[4,5,2]	-9	hSpCas9	negative selection	5222761
134360070	134360092	5	-	27760321	HT29	viability after 13 days	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	0.20424144780499998	[279,218]	[205,362,425]	2	hSpCas9	negative selection	5222762
134312341	134312363	5	+	27760321	HT29	viability after 13 days	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.4312665029255139	[350,273]	[381,218,208]	-5	hSpCas9	negative selection	5222763
134350310	134350332	5	+	27760321	HT29	viability after 13 days	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.2608556014420342	[306,239]	[459,378,305]	3	hSpCas9	negative selection	5222764
134350365	134350387	5	+	27760321	HT29	viability after 13 days	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	-0.8267327722969553	[198,154]	[81,143,120]	-7	hSpCas9	negative selection	5222765
134359909	134359931	5	+	27760321	HT29	viability after 10 days	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-4.091171510458387	[40,31]	[0,2,3]	-9	hSpCas9	negative selection	5306224
134360070	134360092	5	-	27760321	HT29	viability after 10 days	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	-0.3437060706130848	[279,218]	[277,160,293]	-4	hSpCas9	negative selection	5306225
134312341	134312363	5	+	27760321	HT29	viability after 10 days	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.32804246986628477	[350,273]	[434,286,211]	-4	hSpCas9	negative selection	5306226
134350310	134350332	5	+	27760321	HT29	viability after 10 days	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.7773823622647917	[306,239]	[698,674,388]	9	hSpCas9	negative selection	5306227
134350365	134350387	5	+	27760321	HT29	viability after 10 days	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	-1.240234402704849	[198,154]	[63,154,63]	-8	hSpCas9	negative selection	5306228
134359909	134359931	5	+	27760321	MOLM13	viability	AAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-4.7879383016632895	[57,40]	[0,0]	-9	hSpCas9	negative selection	5389687
134360070	134360092	5	-	27760321	MOLM13	viability	CAATTTCATCACGAAAACCTGG	CDKL3	ENSG00000006837	1.5590111663833217	[302,279]	[435,525]	9	hSpCas9	negative selection	5389688
134312341	134312363	5	+	27760321	MOLM13	viability	TAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-1.0043997052868405	[367,350]	[97,103]	-6	hSpCas9	negative selection	5389689
134350310	134350332	5	+	27760321	MOLM13	viability	AGTCCGTATAAATGTCCCCAGG	CDKL3	ENSG00000006837	0.3029779260638915	[397,306]	[40,415]	2	hSpCas9	negative selection	5389690
134350365	134350387	5	+	27760321	MOLM13	viability	GAGCTTAGTAATTCCTGACTGG	CDKL3	ENSG00000006837	0.11593563605668156	[225,198]	[86,165]	0	hSpCas9	negative selection	5389691
134366520	134366543	5	-	27661255	K562	viability	GTAAAAGCCCAGCTTGAAAATGG	CDKL3	ENSG00000006837	-0.09112824019733745	[1805,1781]	[1532,1185]	-3	dCas9-KRAB	negative selection	5469962
134370768	134370791	5	-	27661255	K562	viability	GAGGATCGCACGATCTTCTAAGG	CDKL3	ENSG00000006837	-0.0642619541133061	[667,582]	[545,421]	-2	dCas9-KRAB	negative selection	5469963
134371015	134371038	5	-	27661255	K562	viability	GGTCACGTGAGCGCCTCGCCTGG	CDKL3	ENSG00000006837	0.7750477210902873	[130,309]	[296,296]	9	dCas9-KRAB	negative selection	5469964
134306601	134306624	5	+	27260156	BXPC3	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.010704670184906284	[1076]	[1029,1115,1139,1196]	0	hSpCas9	negative selection	5534969
134321860	134321883	5	-	27260156	BXPC3	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.10163062206343293	[362]	[373,342,489,430]	2	hSpCas9	negative selection	5534970
134306626	134306649	5	-	27260156	BXPC3	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.12540279234204513	[407]	[398,304,564,286]	-3	hSpCas9	negative selection	5534971
134321821	134321844	5	-	27260156	BXPC3	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.26444113364874267	[170]	[212,129,268,256]	6	hSpCas9	negative selection	5599247
134304513	134304536	5	-	27260156	BXPC3	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.4157458222660326	[422]	[259,370,300,405]	-7	hSpCas9	negative selection	5599248
134304543	134304566	5	+	27260156	BXPC3	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.04066023483615622	[1208]	[984,1249,1226,1831]	0	hSpCas9	negative selection	5599249
134306601	134306624	5	+	27260156	A673	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.18646187223409227	[1076]	[1446,1145,975,1003]	-5	hSpCas9	negative selection	5656220
134321860	134321883	5	-	27260156	A673	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.1666887928950364	[362]	[366,402,457,316]	-4	hSpCas9	negative selection	5656221
134306626	134306649	5	-	27260156	A673	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.20126441931413655	[407]	[500,393,382,435]	-5	hSpCas9	negative selection	5656222
134321821	134321844	5	-	27260156	A673	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.24841023418244812	[170]	[233,207,339,188]	6	hSpCas9	negative selection	5720498
134304513	134304536	5	-	27260156	A673	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.6461064676515992	[422]	[350,237,363,350]	-9	hSpCas9	negative selection	5720499
134304543	134304566	5	+	27260156	A673	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.02312059067017236	[1208]	[1571,1520,1351,1462]	0	hSpCas9	negative selection	5720500
134306601	134306624	5	+	27260156	A375	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.33104815970277557	[1076]	[1316,1038,861,808]	-5	hSpCas9	negative selection	5777471
134321860	134321883	5	-	27260156	A375	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.4197334000226653	[362]	[299,337,310,319]	-5	hSpCas9	negative selection	5777472
134306626	134306649	5	-	27260156	A375	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.6357003146560467	[407]	[285,315,282,337]	-7	hSpCas9	negative selection	5777473
134321821	134321844	5	-	27260156	A375	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.3520612757494437	[170]	[342,282,296,116]	5	hSpCas9	negative selection	5841749
134304513	134304536	5	-	27260156	A375	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.3751176628477101	[422]	[248,555,325,410]	-5	hSpCas9	negative selection	5841750
134304543	134304566	5	+	27260156	A375	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.3280872899927689	[1208]	[2133,1867,1632,1497]	5	hSpCas9	negative selection	5841751
134306601	134306624	5	+	27260156	COLO741	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.1906713266735678	[1076]	[1231,1155,1226]	-4	hSpCas9	negative selection	5898722
134321860	134321883	5	-	27260156	COLO741	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.0338266032942483	[362]	[513,498,417]	0	hSpCas9	negative selection	5898723
134306626	134306649	5	-	27260156	COLO741	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.10875122762624465	[407]	[561,524,376]	-2	hSpCas9	negative selection	5898724
134321821	134321844	5	-	27260156	COLO741	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.030797912507106062	[170]	[191,200,243]	0	hSpCas9	negative selection	5963000
134304513	134304536	5	-	27260156	COLO741	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.8780082109444406	[422]	[337,291,257]	-9	hSpCas9	negative selection	5963001
134304543	134304566	5	+	27260156	COLO741	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.09346295678606564	[1208]	[1774,1803,1391]	2	hSpCas9	negative selection	5963002
134306601	134306624	5	+	27260156	CAL120	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.0772367850219291	[1076]	[1340,978,1496]	-1	hSpCas9	negative selection	6019973
134321860	134321883	5	-	27260156	CAL120	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.6725150002070341	[362]	[296,262,291]	-7	hSpCas9	negative selection	6019974
134306626	134306649	5	-	27260156	CAL120	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.1179363549047572	[407]	[598,461,363]	-2	hSpCas9	negative selection	6019975
134321821	134321844	5	-	27260156	CAL120	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.08125702059263173	[170]	[232,304,139]	1	hSpCas9	negative selection	6084251
134304513	134304536	5	-	27260156	CAL120	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.27351207575974257	[422]	[397,265,632]	-4	hSpCas9	negative selection	6084252
134304543	134304566	5	+	27260156	CAL120	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.012154223950183729	[1208]	[1767,1488,1334]	0	hSpCas9	negative selection	6084253
134306601	134306624	5	+	27260156	CADOES1	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.10042790970190829	[1076]	[828,870,933,1109]	-2	hSpCas9	negative selection	6141224
134321860	134321883	5	-	27260156	CADOES1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.24867533170040151	[362]	[321,206,255,353]	-4	hSpCas9	negative selection	6141225
134306626	134306649	5	-	27260156	CADOES1	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.08524344914983686	[407]	[371,200,553,485]	1	hSpCas9	negative selection	6141226
134321821	134321844	5	-	27260156	CADOES1	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.44885825532799317	[170]	[215,185,153,315]	7	hSpCas9	negative selection	6205502
134304513	134304536	5	-	27260156	CADOES1	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.34033753129962574	[422]	[266,335,357,280]	-5	hSpCas9	negative selection	6205503
134304543	134304566	5	+	27260156	CADOES1	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.4890363785772913	[1208]	[1685,1353,1664,1607]	7	hSpCas9	negative selection	6205504
134306601	134306624	5	+	27260156	EWS502	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.05912442031120069	[1076]	[907,920,1288,1304]	-1	hSpCas9	negative selection	6262475
134321860	134321883	5	-	27260156	EWS502	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.45820276288974965	[362]	[195,211,326,405]	-7	hSpCas9	negative selection	6262476
134306626	134306649	5	-	27260156	EWS502	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.0287328718364534	[407]	[314,456,459,476]	0	hSpCas9	negative selection	6262477
134321821	134321844	5	-	27260156	EWS502	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.5055762437620444	[170]	[399,153,260,194]	8	hSpCas9	negative selection	6326753
134304513	134304536	5	-	27260156	EWS502	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.22747280642403636	[422]	[274,402,302,572]	-4	hSpCas9	negative selection	6326754
134304543	134304566	5	+	27260156	EWS502	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.20568720785470673	[1208]	[1406,1284,1711,1519]	3	hSpCas9	negative selection	6326755
134306601	134306624	5	+	27260156	EW8	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.14260513780781547	[1076]	[868,662,761,878]	-3	hSpCas9	negative selection	6383726
134321860	134321883	5	-	27260156	EW8	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.08392068263320157	[362]	[334,299,223,265]	-1	hSpCas9	negative selection	6383727
134306626	134306649	5	-	27260156	EW8	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.29708831289414794	[407]	[304,259,218,303]	-5	hSpCas9	negative selection	6383728
134321821	134321844	5	-	27260156	EW8	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.7699681263370298	[170]	[312,265,166,218]	9	hSpCas9	negative selection	6448004
134304513	134304536	5	-	27260156	EW8	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.40029273011414723	[422]	[312,277,237,218]	-6	hSpCas9	negative selection	6448005
134304543	134304566	5	+	27260156	EW8	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.1442274362047402	[1208]	[934,1189,825,1403]	2	hSpCas9	negative selection	6448006
134306601	134306624	5	+	27260156	CORL105	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.13515780857531	[1076]	[1007,1190,1367,1053]	-3	hSpCas9	negative selection	6504977
134321860	134321883	5	-	27260156	CORL105	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.40492695392993255	[362]	[269,243,439,347]	-6	hSpCas9	negative selection	6504978
134306626	134306649	5	-	27260156	CORL105	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.0027530554436369092	[407]	[301,777,336,455]	0	hSpCas9	negative selection	6504979
134321821	134321844	5	-	27260156	CORL105	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.007871584558595268	[170]	[196,167,279,172]	0	hSpCas9	negative selection	6569255
134304513	134304536	5	-	27260156	CORL105	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.10987431841121695	[422]	[391,423,487,533]	-2	hSpCas9	negative selection	6569256
134304543	134304566	5	+	27260156	CORL105	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.11231310236853664	[1208]	[1411,1532,2100,1159]	2	hSpCas9	negative selection	6569257
134306601	134306624	5	+	27260156	HS294T	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	0.18175646998494122	[1076]	[614,339,387,547]	2	hSpCas9	negative selection	6626228
134321860	134321883	5	-	27260156	HS294T	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.08951856834759375	[362]	[129,86,133,269]	1	hSpCas9	negative selection	6626229
134306626	134306649	5	-	27260156	HS294T	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.21090507515268894	[407]	[136,158,140,100]	-3	hSpCas9	negative selection	6626230
134321821	134321844	5	-	27260156	HS294T	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.3128017629102542	[170]	[45,35,58,76]	-4	hSpCas9	negative selection	6690506
134304513	134304536	5	-	27260156	HS294T	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.6637629367272877	[422]	[64,140,110,96]	-7	hSpCas9	negative selection	6690507
134304543	134304566	5	+	27260156	HS294T	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	-0.16753459106131574	[1208]	[374,471,399,418]	-2	hSpCas9	negative selection	6690508
134306601	134306624	5	+	27260156	HCC44	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.06355621447557791	[1076]	[1496,858,1072,1277]	-1	hSpCas9	negative selection	6747479
134321860	134321883	5	-	27260156	HCC44	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.3404419534271583	[362]	[385,244,327,351]	-5	hSpCas9	negative selection	6747480
134306626	134306649	5	-	27260156	HCC44	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.09052043683551833	[407]	[216,393,738,418]	-1	hSpCas9	negative selection	6747481
134321821	134321844	5	-	27260156	HCC44	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.47804625485693997	[170]	[280,225,377,217]	7	hSpCas9	negative selection	6811757
134304513	134304536	5	-	27260156	HCC44	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.36488080708403425	[422]	[414,216,558,350]	-5	hSpCas9	negative selection	6811758
134304543	134304566	5	+	27260156	HCC44	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.1513894891374501	[1208]	[1285,1311,1918,1618]	2	hSpCas9	negative selection	6811759
134306601	134306624	5	+	27260156	G402	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	0.11726305612500698	[1076]	[1708,1812,1221,1034]	1	hSpCas9	negative selection	6868730
134321860	134321883	5	-	27260156	G402	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.15975060800115987	[362]	[509,376,554,168]	-2	hSpCas9	negative selection	6868731
134306626	134306649	5	-	27260156	G402	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.043488360856501956	[407]	[453,516,555,404]	0	hSpCas9	negative selection	6868732
134321821	134321844	5	-	27260156	G402	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.832757913796448	[170]	[667,249,213,387]	9	hSpCas9	negative selection	6933008
134304513	134304536	5	-	27260156	G402	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.5912970866092713	[422]	[351,367,396,258]	-6	hSpCas9	negative selection	6933009
134304543	134304566	5	+	27260156	G402	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.1615597646334479	[1208]	[1622,1796,1520,1656]	2	hSpCas9	negative selection	6933010
134306601	134306624	5	+	27260156	L33	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	0.03371533437668828	[1076]	[1250,456,746,853]	0	hSpCas9	negative selection	6989981
134321860	134321883	5	-	27260156	L33	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.06153070746722128	[362]	[305,164,218,458]	1	hSpCas9	negative selection	6989982
134306626	134306649	5	-	27260156	L33	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.05599042234094673	[407]	[515,133,229,357]	-1	hSpCas9	negative selection	6989983
134321821	134321844	5	-	27260156	L33	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.34509274111982546	[170]	[122,62,89,118]	-7	hSpCas9	negative selection	7054259
134304513	134304536	5	-	27260156	L33	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.5255039737554337	[422]	[263,113,172,357]	-8	hSpCas9	negative selection	7054260
134304543	134304566	5	+	27260156	L33	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.16035080761219245	[1208]	[1366,545,879,1304]	3	hSpCas9	negative selection	7054261
134306601	134306624	5	+	27260156	K562	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.2371291799706302	[1076]	[1134,523,596,975]	-3	hSpCas9	negative selection	7111232
134321860	134321883	5	-	27260156	K562	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.4864184134941076	[362]	[300,318,189,130]	-5	hSpCas9	negative selection	7111233
134306626	134306649	5	-	27260156	K562	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.7116346765393757	[407]	[202,256,194,227]	-7	hSpCas9	negative selection	7111234
134321821	134321844	5	-	27260156	K562	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.636115880876409	[170]	[229,202,184,312]	7	hSpCas9	negative selection	7175510
134304513	134304536	5	-	27260156	K562	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.5719968190958211	[422]	[301,187,345,181]	-6	hSpCas9	negative selection	7175511
134304543	134304566	5	+	27260156	K562	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	-0.006237274137516957	[1208]	[1369,1339,1033,616]	0	hSpCas9	negative selection	7175512
134306601	134306624	5	+	27260156	HT29	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.08234828621750712	[1076]	[1319,1538,1020,1105]	-2	hSpCas9	negative selection	7232483
134321860	134321883	5	-	27260156	HT29	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.24716113634510778	[362]	[517,408,281,298]	-5	hSpCas9	negative selection	7232484
134306626	134306649	5	-	27260156	HT29	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.23911824941169144	[407]	[588,392,398,319]	-5	hSpCas9	negative selection	7232485
134321821	134321844	5	-	27260156	HT29	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.6358232653439335	[170]	[418,428,250,219]	9	hSpCas9	negative selection	7296761
134304513	134304536	5	-	27260156	HT29	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.4590585588301569	[422]	[480,528,354,174]	-7	hSpCas9	negative selection	7296762
134304543	134304566	5	+	27260156	HT29	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.20489867532239248	[1208]	[1673,1941,1650,1535]	4	hSpCas9	negative selection	7296763
134306601	134306624	5	+	27260156	MHHES1	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.21395463849655383	[1076]	[1075,1410,866,882]	-4	hSpCas9	negative selection	7353734
134321860	134321883	5	-	27260156	MHHES1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.1417118020048484	[362]	[321,495,336,333]	-3	hSpCas9	negative selection	7353735
134306626	134306649	5	-	27260156	MHHES1	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.012723346691679988	[407]	[428,520,502,379]	0	hSpCas9	negative selection	7353736
134321821	134321844	5	-	27260156	MHHES1	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.16990605635528921	[170]	[186,174,139,178]	-3	hSpCas9	negative selection	7418012
134304513	134304536	5	-	27260156	MHHES1	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	6.432400461386933e-05	[422]	[702,441,339,440]	0	hSpCas9	negative selection	7418013
134304543	134304566	5	+	27260156	MHHES1	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.320739701680697	[1208]	[2212,1817,1759,1171]	6	hSpCas9	negative selection	7418014
134306601	134306624	5	+	27260156	MEWO	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	0.03040867953813775	[1076]	[1111,1034,955]	0	hSpCas9	negative selection	7474985
134321860	134321883	5	-	27260156	MEWO	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.05652008045143864	[362]	[332,259,462]	1	hSpCas9	negative selection	7474986
134306626	134306649	5	-	27260156	MEWO	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.10138066851388208	[407]	[409,322,344]	-2	hSpCas9	negative selection	7474987
134321821	134321844	5	-	27260156	MEWO	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.16045985763651283	[170]	[82,89,244]	-4	hSpCas9	negative selection	7539263
134304513	134304536	5	-	27260156	MEWO	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.6751799780759885	[422]	[317,256,181]	-8	hSpCas9	negative selection	7539264
134304543	134304566	5	+	27260156	MEWO	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.008599459695910028	[1208]	[1318,1016,1112]	0	hSpCas9	negative selection	7539265
134306601	134306624	5	+	27260156	LNCAPCLONEFGC	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.18390078920482256	[1076]	[804,929,985,728]	-3	hSpCas9	negative selection	7596236
134321860	134321883	5	-	27260156	LNCAPCLONEFGC	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.6735413349824784	[362]	[151,158,241,280]	-7	hSpCas9	negative selection	7596237
134306626	134306649	5	-	27260156	LNCAPCLONEFGC	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.4699708067258377	[407]	[244,221,343,270]	-6	hSpCas9	negative selection	7596238
134321821	134321844	5	-	27260156	LNCAPCLONEFGC	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.5926115166355528	[170]	[141,283,262,247]	8	hSpCas9	negative selection	7660514
134304513	134304536	5	-	27260156	LNCAPCLONEFGC	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.7049207984246648	[422]	[282,273,203,170]	-8	hSpCas9	negative selection	7660515
134304543	134304566	5	+	27260156	LNCAPCLONEFGC	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.06662289288641943	[1208]	[1144,1112,1279,1070]	1	hSpCas9	negative selection	7660516
134306601	134306624	5	+	27260156	PANC0327	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.023418115190897204	[1076]	[747,895,1035,1074]	0	hSpCas9	negative selection	7717487
134321860	134321883	5	-	27260156	PANC0327	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.2408704160519453	[362]	[280,282,636,327]	3	hSpCas9	negative selection	7717488
134306626	134306649	5	-	27260156	PANC0327	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.4061957352046478	[407]	[330,329,108,320]	-5	hSpCas9	negative selection	7717489
134321821	134321844	5	-	27260156	PANC0327	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.16013004323999946	[170]	[152,144,145,99]	-2	hSpCas9	negative selection	7781765
134304513	134304536	5	-	27260156	PANC0327	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.364434287300594	[422]	[192,243,548,179]	-5	hSpCas9	negative selection	7781766
134304543	134304566	5	+	27260156	PANC0327	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.10691194358461797	[1208]	[1356,1243,1035,993]	1	hSpCas9	negative selection	7781767
134306601	134306624	5	+	27260156	NCIH2009	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.18486031135232528	[1076]	[1505,1217,1282]	-3	hSpCas9	negative selection	7838738
134321860	134321883	5	-	27260156	NCIH2009	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-1.0148386932638331	[362]	[365,210,198]	-8	hSpCas9	negative selection	7838739
134306626	134306649	5	-	27260156	NCIH2009	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.22541444755137904	[407]	[487,597,373]	-3	hSpCas9	negative selection	7838740
134321821	134321844	5	-	27260156	NCIH2009	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.3156665207709235	[170]	[252,284,344]	4	hSpCas9	negative selection	7903016
134304513	134304536	5	-	27260156	NCIH2009	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	0.053026583173720915	[422]	[619,595,623]	0	hSpCas9	negative selection	7903017
134304543	134304566	5	+	27260156	NCIH2009	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.1895570905867492	[1208]	[2399,1671,1801]	2	hSpCas9	negative selection	7903018
134306601	134306624	5	+	27260156	NCIH1373	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.08327742413723116	[1076]	[1031,1140,1431,238]	-1	hSpCas9	negative selection	7959989
134321860	134321883	5	-	27260156	NCIH1373	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-1.2128126616379482	[362]	[134,274,131,36]	-8	hSpCas9	negative selection	7959990
134306626	134306649	5	-	27260156	NCIH1373	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.3667403172554627	[407]	[657,671,366,175]	3	hSpCas9	negative selection	7959991
134321821	134321844	5	-	27260156	NCIH1373	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.24675398513971647	[170]	[229,76,88,72]	-2	hSpCas9	negative selection	8024267
134304513	134304536	5	-	27260156	NCIH1373	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.22721275449489306	[422]	[244,493,467,97]	-2	hSpCas9	negative selection	8024268
134304543	134304566	5	+	27260156	NCIH1373	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.7395122473626008	[1208]	[2269,2479,2198,539]	7	hSpCas9	negative selection	8024269
134306601	134306624	5	+	27260156	PATU8902	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.3256445132543425	[1076]	[1277,1077,1161,1276]	-3	hSpCas9	negative selection	8081240
134321860	134321883	5	-	27260156	PATU8902	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-1.3650141924798478	[362]	[455,65,87,197]	-8	hSpCas9	negative selection	8081241
134306626	134306649	5	-	27260156	PATU8902	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-1.5726229791826456	[407]	[257,189,82,267]	-8	hSpCas9	negative selection	8081242
134321821	134321844	5	-	27260156	PATU8902	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.017586604845863496	[170]	[669,244,17,59]	0	hSpCas9	negative selection	8145518
134304513	134304536	5	-	27260156	PATU8902	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-1.2053240371423621	[422]	[233,278,117,447]	-8	hSpCas9	negative selection	8145519
134304543	134304566	5	+	27260156	PATU8902	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.156007516247469	[1208]	[1726,2040,1726,2056]	1	hSpCas9	negative selection	8145520
134306601	134306624	5	+	27260156	PANC1	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.1973806605292563	[1076]	[761,1044,951,548]	-3	hSpCas9	negative selection	8202491
134321860	134321883	5	-	27260156	PANC1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.45080642280658995	[362]	[216,360,212,156]	-6	hSpCas9	negative selection	8202492
134306626	134306649	5	-	27260156	PANC1	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.05054610618856631	[407]	[390,303,447,300]	0	hSpCas9	negative selection	8202493
134321821	134321844	5	-	27260156	PANC1	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.24219986747711797	[170]	[228,167,130,162]	4	hSpCas9	negative selection	8266769
134304513	134304536	5	-	27260156	PANC1	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.32593375086744236	[422]	[269,419,293,210]	-5	hSpCas9	negative selection	8266770
134304543	134304566	5	+	27260156	PANC1	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.2886937156289988	[1208]	[1157,1661,1521,863]	4	hSpCas9	negative selection	8266771
134306601	134306624	5	+	27260156	PANC0813	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	0.024336283403255665	[1076]	[1260,1089,1434,1352]	0	hSpCas9	negative selection	8323742
134321860	134321883	5	-	27260156	PANC0813	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.07427609326860829	[362]	[426,593,352,419]	1	hSpCas9	negative selection	8323743
134306626	134306649	5	-	27260156	PANC0813	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.08148597468999859	[407]	[749,358,454,486]	1	hSpCas9	negative selection	8323744
134321821	134321844	5	-	27260156	PANC0813	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.34096127247397545	[170]	[168,191,169,106]	-5	hSpCas9	negative selection	8388020
134304513	134304536	5	-	27260156	PANC0813	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.2739268775280199	[422]	[265,327,474,552]	-4	hSpCas9	negative selection	8388021
134304543	134304566	5	+	27260156	PANC0813	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	-0.035049898347139674	[1208]	[1609,1309,1426,1224]	0	hSpCas9	negative selection	8388022
134306601	134306624	5	+	27260156	RDES	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.03089974574544252	[1076]	[1053,1154,1115,1577]	0	hSpCas9	negative selection	8444993
134321860	134321883	5	-	27260156	RDES	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.4420746209653624	[362]	[227,310,394,305]	-6	hSpCas9	negative selection	8444994
134306626	134306649	5	-	27260156	RDES	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.21547185220317275	[407]	[349,438,324,510]	-4	hSpCas9	negative selection	8444995
134321821	134321844	5	-	27260156	RDES	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.5303675462324599	[170]	[263,289,245,336]	8	hSpCas9	negative selection	8509271
134304513	134304536	5	-	27260156	RDES	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.5887693885244684	[422]	[302,306,263,428]	-7	hSpCas9	negative selection	8509272
134304543	134304566	5	+	27260156	RDES	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.2959126620694934	[1208]	[1238,1729,1667,2334]	5	hSpCas9	negative selection	8509273
134306601	134306624	5	+	27260156	PC3	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.12627017978558186	[1076]	[568,830,1588,1296]	-3	hSpCas9	negative selection	8566244
134321860	134321883	5	-	27260156	PC3	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.2603108996366758	[362]	[227,395,705,571]	5	hSpCas9	negative selection	8566245
134306626	134306649	5	-	27260156	PC3	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.12001689095296639	[407]	[281,430,949,324]	2	hSpCas9	negative selection	8566246
134321821	134321844	5	-	27260156	PC3	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.15665273557281467	[170]	[132,240,326,109]	3	hSpCas9	negative selection	8630522
134304513	134304536	5	-	27260156	PC3	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.4443327978209698	[422]	[234,309,468,282]	-7	hSpCas9	negative selection	8630523
134304543	134304566	5	+	27260156	PC3	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	-0.004569219382411394	[1208]	[756,1220,1888,1284]	0	hSpCas9	negative selection	8630524
134306601	134306624	5	+	27260156	PATU8988T	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.26508941466969027	[1076]	[576,1110,764,1049]	-4	hSpCas9	negative selection	8687495
134321860	134321883	5	-	27260156	PATU8988T	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.024594229366446507	[362]	[268,454,348,363]	0	hSpCas9	negative selection	8687496
134306626	134306649	5	-	27260156	PATU8988T	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.2949877638520024	[407]	[327,187,377,382]	-5	hSpCas9	negative selection	8687497
134321821	134321844	5	-	27260156	PATU8988T	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.7275771854528493	[170]	[363,280,132,322]	9	hSpCas9	negative selection	8751773
134304513	134304536	5	-	27260156	PATU8988T	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	0.014150928158994741	[422]	[503,402,196,560]	0	hSpCas9	negative selection	8751774
134304543	134304566	5	+	27260156	PATU8988T	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.2541271089405126	[1208]	[1402,1019,1818,1280]	4	hSpCas9	negative selection	8751775
134306601	134306624	5	+	27260156	T47D	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.046837507349144714	[1076]	[1304,1211,1188,1150]	-1	hSpCas9	negative selection	8808746
134321860	134321883	5	-	27260156	T47D	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.14504356713404293	[362]	[359,369,418,380]	-3	hSpCas9	negative selection	8808747
134306626	134306649	5	-	27260156	T47D	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.12739049888263745	[407]	[433,372,497,439]	-3	hSpCas9	negative selection	8808748
134321821	134321844	5	-	27260156	T47D	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.49120442989831326	[170]	[309,251,270,289]	8	hSpCas9	negative selection	8873024
134304513	134304536	5	-	27260156	T47D	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.7645091939418398	[422]	[226,247,273,418]	-9	hSpCas9	negative selection	8873025
134304543	134304566	5	+	27260156	T47D	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.1363247525183371	[1208]	[1516,1350,1644,1698]	3	hSpCas9	negative selection	8873026
134306601	134306624	5	+	27260156	SU8686	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.03623811096585228	[1076]	[930,959,1138,1174]	0	hSpCas9	negative selection	8929997
134321860	134321883	5	-	27260156	SU8686	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.3606928626401234	[362]	[312,233,335,231]	-5	hSpCas9	negative selection	8929998
134306626	134306649	5	-	27260156	SU8686	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	0.14684799401905202	[407]	[607,333,417,418]	2	hSpCas9	negative selection	8929999
134321821	134321844	5	-	27260156	SU8686	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.12067979213443691	[170]	[101,104,186,258]	-2	hSpCas9	negative selection	8994275
134304513	134304536	5	-	27260156	SU8686	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.7719159579913891	[422]	[291,232,184,268]	-8	hSpCas9	negative selection	8994276
134304543	134304566	5	+	27260156	SU8686	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.21132785645075858	[1208]	[1260,1399,1213,1728]	3	hSpCas9	negative selection	8994277
134306601	134306624	5	+	27260156	SKES1	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.008679443663201614	[1076]	[989,1359,783,1144]	0	hSpCas9	negative selection	9051248
134321860	134321883	5	-	27260156	SKES1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.0013406358992358869	[362]	[416,480,297,279]	0	hSpCas9	negative selection	9051249
134306626	134306649	5	-	27260156	SKES1	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.32476353924613044	[407]	[489,281,285,263]	-6	hSpCas9	negative selection	9051250
134321821	134321844	5	-	27260156	SKES1	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.3501773954520966	[170]	[162,63,167,133]	-6	hSpCas9	negative selection	9115526
134304513	134304536	5	-	27260156	SKES1	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.4485587260135383	[422]	[407,272,267,295]	-7	hSpCas9	negative selection	9115527
134304543	134304566	5	+	27260156	SKES1	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.1031579978105801	[1208]	[1603,1248,1275,1099]	2	hSpCas9	negative selection	9115528
134306601	134306624	5	+	27260156	TOV112D	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	0.019997891519497824	[1076]	[921,1502,1217,823]	0	hSpCas9	negative selection	9172499
134321860	134321883	5	-	27260156	TOV112D	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.039886054707915286	[362]	[368,334,435,272]	-1	hSpCas9	negative selection	9172500
134306626	134306649	5	-	27260156	TOV112D	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.3487171783382649	[407]	[272,315,338,348]	-6	hSpCas9	negative selection	9172501
134321821	134321844	5	-	27260156	TOV112D	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	-0.1612095597002623	[170]	[95,298,114,133]	-3	hSpCas9	negative selection	9236777
134304513	134304536	5	-	27260156	TOV112D	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.6381357934412508	[422]	[320,385,230,184]	-8	hSpCas9	negative selection	9236778
134304543	134304566	5	+	27260156	TOV112D	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	-0.0021714095962050983	[1208]	[1066,1927,1114,897]	0	hSpCas9	negative selection	9236779
134306601	134306624	5	+	27260156	TC71	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.14685102271918926	[1076]	[1004,1117,1055,988]	-4	hSpCas9	negative selection	9293750
134321860	134321883	5	-	27260156	TC71	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.1307669240878094	[362]	[493,443,314,454]	3	hSpCas9	negative selection	9293751
134306626	134306649	5	-	27260156	TC71	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.14422601619743222	[407]	[386,459,360,374]	-4	hSpCas9	negative selection	9293752
134321821	134321844	5	-	27260156	TC71	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.16607944450565193	[170]	[212,219,225,159]	4	hSpCas9	negative selection	9358028
134304513	134304536	5	-	27260156	TC71	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.2768042188888694	[422]	[419,319,438,310]	-6	hSpCas9	negative selection	9358029
134304543	134304566	5	+	27260156	TC71	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	0.09681644014036794	[1208]	[1319,1555,1418,1239]	2	hSpCas9	negative selection	9358030
134306601	134306624	5	+	27260156	TC32	viability	TGCCTTACTTGAATAGGACCTGG	CDKL3	ENSG00000006837	-0.05439783368579576	[1076]	[905,733,1462,918]	-1	hSpCas9	negative selection	9415001
134321860	134321883	5	-	27260156	TC32	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.06410563589502949	[362]	[192,350,439,327]	-1	hSpCas9	negative selection	9415002
134306626	134306649	5	-	27260156	TC32	viability	TATGCCTAATAGCAGGCAAGAGG	CDKL3	ENSG00000006837	-0.1534560102786087	[407]	[428,210,400,367]	-3	hSpCas9	negative selection	9415003
134321821	134321844	5	-	27260156	TC32	viability	TCTTCCTAGTAGTTCTGATTTGG	CDKL3	ENSG00000006837	0.20361340562811336	[170]	[193,211,144,155]	3	hSpCas9	negative selection	9479279
134304513	134304536	5	-	27260156	TC32	viability	AACAGGTCACAGTGACCAAATGG	CDKL3	ENSG00000006837	-0.6720220408451554	[422]	[383,116,315,207]	-8	hSpCas9	negative selection	9479280
134304543	134304566	5	+	27260156	TC32	viability	TAAATATACCCTTCTCCATTTGG	CDKL3	ENSG00000006837	-0.027395901172009296	[1208]	[1019,839,1637,1100]	0	hSpCas9	negative selection	9479281
134298688	134298711	5	-	27869803	HPAFII	viability after 27 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.6175810382874778	[116]	[56,25,NaN]	-4	hSpCas9	negative selection	9589961
134308125	134308148	5	+	27869803	HPAFII	viability after 27 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.9341888012415764	[376]	[142,70,NaN]	-6	hSpCas9	negative selection	9589962
134308346	134308369	5	-	27869803	HPAFII	viability after 27 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.49239638198508323	[294]	[185,244,NaN]	4	hSpCas9	negative selection	9589963
134312340	134312363	5	+	27869803	HPAFII	viability after 27 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.29833825671284814	[196]	[140,115,NaN]	2	hSpCas9	negative selection	9589964
134298688	134298711	5	-	27869803	HPAFII	viability after 15 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	0.2119196319451616	[116]	[210,104,NaN]	2	hSpCas9	negative selection	9672410
134308125	134308148	5	+	27869803	HPAFII	viability after 15 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-1.021907325872533	[376]	[201,197,NaN]	-8	hSpCas9	negative selection	9672411
134308346	134308369	5	-	27869803	HPAFII	viability after 15 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	-0.005184185181381917	[294]	[400,262,NaN]	0	hSpCas9	negative selection	9672412
134312340	134312363	5	+	27869803	HPAFII	viability after 15 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.4314053543189174	[196]	[156,156,NaN]	-5	hSpCas9	negative selection	9672413
134298688	134298711	5	-	27869803	ASPC1	viability after 36 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.5352105340349962	[307]	[72,8,125]	-5	hSpCas9	negative selection	9754859
134308125	134308148	5	+	27869803	ASPC1	viability after 36 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	0.29712454427456325	[919]	[629,399,220]	3	hSpCas9	negative selection	9754860
134308346	134308369	5	-	27869803	ASPC1	viability after 36 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.6128102585641749	[613]	[468,385,178]	6	hSpCas9	negative selection	9754861
134312340	134312363	5	+	27869803	ASPC1	viability after 36 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.627570143457026	[402]	[421,290,12]	6	hSpCas9	negative selection	9754862
134298688	134298711	5	-	27869803	PATU8988S	viability after 35 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.23655575735829915	[305]	[149,58,NaN]	-3	hSpCas9	negative selection	9837308
134308125	134308148	5	+	27869803	PATU8988S	viability after 35 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.13550266309986886	[697]	[219,291,NaN]	-1	hSpCas9	negative selection	9837309
134308346	134308369	5	-	27869803	PATU8988S	viability after 35 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.29772746516900755	[576]	[351,218,NaN]	3	hSpCas9	negative selection	9837310
134312340	134312363	5	+	27869803	PATU8988S	viability after 35 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	-0.5828808485821868	[454]	[53,190,NaN]	-5	hSpCas9	negative selection	9837311
134298688	134298711	5	-	27869803	PATU8988S	viability after 31 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	0.35049163686920065	[305]	[199,98,NaN]	4	hSpCas9	negative selection	9919757
134308125	134308148	5	+	27869803	PATU8988S	viability after 31 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.823164226225524	[697]	[100,228,NaN]	-7	hSpCas9	negative selection	9919758
134308346	134308369	5	-	27869803	PATU8988S	viability after 31 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.4834216328280241	[576]	[406,212,NaN]	6	hSpCas9	negative selection	9919759
134312340	134312363	5	+	27869803	PATU8988S	viability after 31 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.1301598499495894	[454]	[187,211,NaN]	1	hSpCas9	negative selection	9919760
134298688	134298711	5	-	27869803	HPAFII	viability after 35 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.5663480716993672	[116]	[39,39,NaN]	-3	hSpCas9	negative selection	10002206
134308125	134308148	5	+	27869803	HPAFII	viability after 35 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-1.112953180070352	[376]	[99,74,NaN]	-6	hSpCas9	negative selection	10002207
134308346	134308369	5	-	27869803	HPAFII	viability after 35 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.24489742445926022	[294]	[120,239,NaN]	1	hSpCas9	negative selection	10002208
134312340	134312363	5	+	27869803	HPAFII	viability after 35 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.6480319220249088	[196]	[128,186,NaN]	4	hSpCas9	negative selection	10002209
134298688	134298711	5	-	27869803	HPAFII	viability after 31 days	GGTGGAGATGGCCATTGCGAGGG	CDKL3	ENSG00000006837	-0.9127244742156497	[116]	[20,49,NaN]	-5	hSpCas9	negative selection	10084655
134308125	134308148	5	+	27869803	HPAFII	viability after 31 days	TGTTACAGCTCACCTCACACTGG	CDKL3	ENSG00000006837	-0.6874633405084494	[376]	[150,109,NaN]	-4	hSpCas9	negative selection	10084656
134308346	134308369	5	-	27869803	HPAFII	viability after 31 days	TGAAGGTGGACTTGGTCAACAGG	CDKL3	ENSG00000006837	0.3261151771422995	[294]	[96,327,NaN]	2	hSpCas9	negative selection	10084657
134312340	134312363	5	+	27869803	HPAFII	viability after 31 days	CTAGATGATATCCTGTCAGCAGG	CDKL3	ENSG00000006837	0.4566683495606908	[196]	[167,133,NaN]	3	hSpCas9	negative selection	10084658
134308225	134308248	5	-	28162770	P31FUJ	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.35626469463951405	[116]	[175]	4	hSpCas9	negative selection	10130840
134308354	134308377	5	-	28162770	P31FUJ	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.6407230501767064	[416]	[763]	7	hSpCas9	negative selection	10130841
134359908	134359931	5	+	28162770	P31FUJ	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-0.12177089202563479	[199]	[215]	-1	hSpCas9	negative selection	10130842
134321860	134321883	5	-	28162770	P31FUJ	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-3.969767798580585	[39]	[2]	-9	hSpCas9	negative selection	10130843
134321837	134321860	5	+	28162770	P31FUJ	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-0.7414138190054202	[137]	[96]	-5	hSpCas9	negative selection	10130844
134308248	134308271	5	+	28162770	P31FUJ	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.41476430469872083	[232]	[364]	4	hSpCas9	negative selection	10130845
134366501	134366524	5	-	28162770	P31FUJ	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.02658442440427078	[527]	[631]	0	hSpCas9	negative selection	10130846
134366477	134366500	5	-	28162770	P31FUJ	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.15485885593316007	[132]	[173]	1	hSpCas9	negative selection	10130847
134350325	134350348	5	-	28162770	P31FUJ	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.34386551757505646	[406]	[606]	4	hSpCas9	negative selection	10130848
134319371	134319394	5	+	28162770	P31FUJ	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.49850852688860425	[408]	[678]	5	hSpCas9	negative selection	10130849
134308225	134308248	5	-	28162770	TF1	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10300206
134308354	134308377	5	-	28162770	TF1	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	NaN	[NaN]	[681]	1	hSpCas9	negative selection	10300207
134359908	134359931	5	+	28162770	TF1	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	NaN	[NaN]	[187]	1	hSpCas9	negative selection	10300208
134321860	134321883	5	-	28162770	TF1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10300209
134321837	134321860	5	+	28162770	TF1	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10300210
134308248	134308271	5	+	28162770	TF1	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	NaN	[NaN]	[212]	1	hSpCas9	negative selection	10300211
134366501	134366524	5	-	28162770	TF1	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	NaN	[NaN]	[460]	1	hSpCas9	negative selection	10300212
134366477	134366500	5	-	28162770	TF1	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10300213
134350325	134350348	5	-	28162770	TF1	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	NaN	[NaN]	[289]	1	hSpCas9	negative selection	10300214
134319371	134319394	5	+	28162770	TF1	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	NaN	[NaN]	[530]	1	hSpCas9	negative selection	10300215
134308225	134308248	5	-	28162770	SKM1	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	1.0899421253127983	[37]	[142]	8	hSpCas9	negative selection	10469572
134308354	134308377	5	-	28162770	SKM1	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.5575869652525486	[102]	[267]	5	hSpCas9	negative selection	10469573
134359908	134359931	5	+	28162770	SKM1	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	2.8547033713267265	[32]	[421]	9	hSpCas9	negative selection	10469574
134321860	134321883	5	-	28162770	SKM1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.26546114322833403	[15]	[33]	2	hSpCas9	negative selection	10469575
134321837	134321860	5	+	28162770	SKM1	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-1.1021096172147407	[33]	[27]	-7	hSpCas9	negative selection	10469576
134308248	134308271	5	+	28162770	SKM1	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	1.5518131385303253	[70]	[367]	9	hSpCas9	negative selection	10469577
134366501	134366524	5	-	28162770	SKM1	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.7230680755756379	[109]	[320]	7	hSpCas9	negative selection	10469578
134366477	134366500	5	-	28162770	SKM1	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.8517700696570067	[20]	[66]	7	hSpCas9	negative selection	10469579
134350325	134350348	5	-	28162770	SKM1	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.17799830197799427	[124]	[249]	1	hSpCas9	negative selection	10469580
134319371	134319394	5	+	28162770	SKM1	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.12011738589749466	[88]	[170]	1	hSpCas9	negative selection	10469581
134308225	134308248	5	-	28162770	SKM1	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	1.0899421253127983	[37]	[142]	8	hSpCas9	negative selection	10638938
134308354	134308377	5	-	28162770	SKM1	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.5575869652525486	[102]	[267]	5	hSpCas9	negative selection	10638939
134359908	134359931	5	+	28162770	SKM1	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	2.8547033713267265	[32]	[421]	9	hSpCas9	negative selection	10638940
134321860	134321883	5	-	28162770	SKM1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.26546114322833403	[15]	[33]	2	hSpCas9	negative selection	10638941
134321837	134321860	5	+	28162770	SKM1	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-1.1021096172147407	[33]	[27]	-7	hSpCas9	negative selection	10638942
134308248	134308271	5	+	28162770	SKM1	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	1.5518131385303253	[70]	[367]	9	hSpCas9	negative selection	10638943
134366501	134366524	5	-	28162770	SKM1	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.7230680755756379	[109]	[320]	7	hSpCas9	negative selection	10638944
134366477	134366500	5	-	28162770	SKM1	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.8517700696570067	[20]	[66]	7	hSpCas9	negative selection	10638945
134350325	134350348	5	-	28162770	SKM1	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.17799830197799427	[124]	[249]	1	hSpCas9	negative selection	10638946
134319371	134319394	5	+	28162770	SKM1	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.12011738589749466	[88]	[170]	1	hSpCas9	negative selection	10638947
134308225	134308248	5	-	28162770	PL21	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	1.912337303506584	[140]	[230]	9	hSpCas9	negative selection	10808304
134308354	134308377	5	-	28162770	PL21	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.4273732988952671	[339]	[198]	4	hSpCas9	negative selection	10808305
134359908	134359931	5	+	28162770	PL21	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.6493253361800096	[166]	[113]	5	hSpCas9	negative selection	10808306
134321860	134321883	5	-	28162770	PL21	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.47221915992612096	[52]	[31]	4	hSpCas9	negative selection	10808307
134321837	134321860	5	+	28162770	PL21	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	0.3618906844859324	[117]	[65]	3	hSpCas9	negative selection	10808308
134308248	134308271	5	+	28162770	PL21	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.9344797392487028	[219]	[182]	7	hSpCas9	negative selection	10808309
134366501	134366524	5	-	28162770	PL21	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	-0.3177086903732992	[377]	[131]	-2	hSpCas9	negative selection	10808310
134366477	134366500	5	-	28162770	PL21	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-0.8823225457026527	[71]	[16]	-6	hSpCas9	negative selection	10808311
134350325	134350348	5	-	28162770	PL21	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.3484623614464215	[313]	[173]	3	hSpCas9	negative selection	10808312
134319371	134319394	5	+	28162770	PL21	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.4787148712188921	[276]	[167]	4	hSpCas9	negative selection	10808313
134308225	134308248	5	-	28162770	P31FUJ	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.35626469463951405	[116]	[175]	4	hSpCas9	negative selection	10977670
134308354	134308377	5	-	28162770	P31FUJ	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.6407230501767064	[416]	[763]	7	hSpCas9	negative selection	10977671
134359908	134359931	5	+	28162770	P31FUJ	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-0.12177089202563479	[199]	[215]	-1	hSpCas9	negative selection	10977672
134321860	134321883	5	-	28162770	P31FUJ	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-3.969767798580585	[39]	[2]	-9	hSpCas9	negative selection	10977673
134321837	134321860	5	+	28162770	P31FUJ	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-0.7414138190054202	[137]	[96]	-5	hSpCas9	negative selection	10977674
134308248	134308271	5	+	28162770	P31FUJ	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.41476430469872083	[232]	[364]	4	hSpCas9	negative selection	10977675
134366501	134366524	5	-	28162770	P31FUJ	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.02658442440427078	[527]	[631]	0	hSpCas9	negative selection	10977676
134366477	134366500	5	-	28162770	P31FUJ	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.15485885593316007	[132]	[173]	1	hSpCas9	negative selection	10977677
134350325	134350348	5	-	28162770	P31FUJ	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.34386551757505646	[406]	[606]	4	hSpCas9	negative selection	10977678
134319371	134319394	5	+	28162770	P31FUJ	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.49850852688860425	[408]	[678]	5	hSpCas9	negative selection	10977679
134308225	134308248	5	-	28162770	OCIAML5	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.8037172670468559	[52]	[166]	7	hSpCas9	negative selection	11147036
134308354	134308377	5	-	28162770	OCIAML5	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.512505861431859	[279]	[720]	4	hSpCas9	negative selection	11147037
134359908	134359931	5	+	28162770	OCIAML5	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.5375002408987286	[99]	[261]	5	hSpCas9	negative selection	11147038
134321860	134321883	5	-	28162770	OCIAML5	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.5171672388017221	[11]	[30]	4	hSpCas9	negative selection	11147039
134321837	134321860	5	+	28162770	OCIAML5	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-0.2956732223396117	[67]	[99]	-2	hSpCas9	negative selection	11147040
134308248	134308271	5	+	28162770	OCIAML5	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	1.5118168404647438	[121]	[627]	9	hSpCas9	negative selection	11147041
134366501	134366524	5	-	28162770	OCIAML5	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.46725972883508515	[221]	[553]	4	hSpCas9	negative selection	11147042
134366477	134366500	5	-	28162770	OCIAML5	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-1.8895412762826598	[38]	[18]	-7	hSpCas9	negative selection	11147043
134350325	134350348	5	-	28162770	OCIAML5	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.39321998681962866	[258]	[613]	3	hSpCas9	negative selection	11147044
134319371	134319394	5	+	28162770	OCIAML5	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.5289090923412139	[224]	[585]	4	hSpCas9	negative selection	11147045
134308225	134308248	5	-	28162770	EOL1	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.5158517991655175	[226]	[170]	4	hSpCas9	negative selection	11316402
134308354	134308377	5	-	28162770	EOL1	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.3038006957094047	[448]	[291]	2	hSpCas9	negative selection	11316403
134359908	134359931	5	+	28162770	EOL1	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	-0.7610186700890272	[385]	[119]	-5	hSpCas9	negative selection	11316404
134321860	134321883	5	-	28162770	EOL1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.2069475022712597	[73]	[44]	1	hSpCas9	negative selection	11316405
134321837	134321860	5	+	28162770	EOL1	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	0.7725446781254844	[249]	[224]	6	hSpCas9	negative selection	11316406
134308248	134308271	5	+	28162770	EOL1	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.9399366645839613	[372]	[376]	7	hSpCas9	negative selection	11316407
134366501	134366524	5	-	28162770	EOL1	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.6219015098378841	[575]	[466]	5	hSpCas9	negative selection	11316408
134366477	134366500	5	-	28162770	EOL1	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	2.627079868672867	[105]	[344]	9	hSpCas9	negative selection	11316409
134350325	134350348	5	-	28162770	EOL1	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.3839793902078319	[479]	[329]	3	hSpCas9	negative selection	11316410
134319371	134319394	5	+	28162770	EOL1	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.3690892651594616	[362]	[246]	3	hSpCas9	negative selection	11316411
134308225	134308248	5	-	28162770	MOLM13	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.8417042180969095	[212]	[275]	6	hSpCas9	negative selection	11485768
134308354	134308377	5	-	28162770	MOLM13	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.65567416839644	[445]	[507]	5	hSpCas9	negative selection	11485769
134359908	134359931	5	+	28162770	MOLM13	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	1.0592496534638856	[299]	[451]	7	hSpCas9	negative selection	11485770
134321860	134321883	5	-	28162770	MOLM13	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-1.2895403151813432	[70]	[20]	-6	hSpCas9	negative selection	11485771
134321837	134321860	5	+	28162770	MOLM13	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	1.7835312135845098	[183]	[457]	9	hSpCas9	negative selection	11485772
134308248	134308271	5	+	28162770	MOLM13	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	1.0434444290100369	[358]	[534]	7	hSpCas9	negative selection	11485773
134366501	134366524	5	-	28162770	MOLM13	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	-0.1608134347065775	[585]	[378]	-1	hSpCas9	negative selection	11485774
134366477	134366500	5	-	28162770	MOLM13	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-0.2690762126216275	[94]	[56]	-2	hSpCas9	negative selection	11485775
134350325	134350348	5	-	28162770	MOLM13	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.04841691092539324	[542]	[405]	0	hSpCas9	negative selection	11485776
134319371	134319394	5	+	28162770	MOLM13	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.4074886750756166	[438]	[420]	3	hSpCas9	negative selection	11485777
134308225	134308248	5	-	28162770	HEL	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	1.3979666325592914	[156]	[264]	9	hSpCas9	negative selection	11655134
134308354	134308377	5	-	28162770	HEL	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.944181299437241	[382]	[471]	7	hSpCas9	negative selection	11655135
134359908	134359931	5	+	28162770	HEL	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.9985005219635947	[235]	[301]	8	hSpCas9	negative selection	11655136
134321860	134321883	5	-	28162770	HEL	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	0.8044899019969693	[58]	[65]	7	hSpCas9	negative selection	11655137
134321837	134321860	5	+	28162770	HEL	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	1.0083883043170374	[155]	[200]	8	hSpCas9	negative selection	11655138
134308248	134308271	5	+	28162770	HEL	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	1.0767594346467737	[301]	[407]	8	hSpCas9	negative selection	11655139
134366501	134366524	5	-	28162770	HEL	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.9818499385610763	[433]	[548]	8	hSpCas9	negative selection	11655140
134366477	134366500	5	-	28162770	HEL	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.7821418886657734	[68]	[75]	6	hSpCas9	negative selection	11655141
134350325	134350348	5	-	28162770	HEL	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	-0.9276875755629188	[394]	[132]	-5	hSpCas9	negative selection	11655142
134319371	134319394	5	+	28162770	HEL	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	-0.10003238384705482	[414]	[247]	0	hSpCas9	negative selection	11655143
134308225	134308248	5	-	28162770	MV411	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.5898297482298531	[111]	[141]	5	hSpCas9	negative selection	11824500
134308354	134308377	5	-	28162770	MV411	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.3231372769146279	[296]	[312]	3	hSpCas9	negative selection	11824501
134359908	134359931	5	+	28162770	MV411	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	1.434206062388502	[122]	[279]	9	hSpCas9	negative selection	11824502
134321860	134321883	5	-	28162770	MV411	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.6242383522416852	[85]	[46]	-4	hSpCas9	negative selection	11824503
134321837	134321860	5	+	28162770	MV411	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	1.2020456479687611	[112]	[218]	9	hSpCas9	negative selection	11824504
134308248	134308271	5	+	28162770	MV411	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.29857639977457634	[193]	[200]	2	hSpCas9	negative selection	11824505
134366501	134366524	5	-	28162770	MV411	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.48114528534705725	[380]	[447]	4	hSpCas9	negative selection	11824506
134366477	134366500	5	-	28162770	MV411	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.6685752495980369	[58]	[78]	6	hSpCas9	negative selection	11824507
134350325	134350348	5	-	28162770	MV411	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	-0.7309755870090788	[397]	[201]	-5	hSpCas9	negative selection	11824508
134319371	134319394	5	+	28162770	MV411	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.5152889729143451	[298]	[359]	4	hSpCas9	negative selection	11824509
134308225	134308248	5	-	28162770	MONOMAC1	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	-0.29219408009989384	[93]	[87]	-3	hSpCas9	negative selection	11993866
134308354	134308377	5	-	28162770	MONOMAC1	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.713102540427313	[206]	[388]	6	hSpCas9	negative selection	11993867
134359908	134359931	5	+	28162770	MONOMAC1	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.09374254925714434	[102]	[125]	1	hSpCas9	negative selection	11993868
134321860	134321883	5	-	28162770	MONOMAC1	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.3986707082292038	[22]	[19]	-3	hSpCas9	negative selection	11993869
134321837	134321860	5	+	28162770	MONOMAC1	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	0.5172086706065688	[63]	[104]	5	hSpCas9	negative selection	11993870
134308248	134308271	5	+	28162770	MONOMAC1	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	0.13227077819340616	[155]	[195]	1	hSpCas9	negative selection	11993871
134366501	134366524	5	-	28162770	MONOMAC1	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.6684621173520346	[263]	[480]	6	hSpCas9	negative selection	11993872
134366477	134366500	5	-	28162770	MONOMAC1	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	-1.7275515637583334	[77]	[26]	-8	hSpCas9	negative selection	11993873
134350325	134350348	5	-	28162770	MONOMAC1	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.14626489862037584	[200]	[254]	1	hSpCas9	negative selection	11993874
134319371	134319394	5	+	28162770	MONOMAC1	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.180847653801824	[176]	[229]	1	hSpCas9	negative selection	11993875
134308225	134308248	5	-	28162770	OCIAML2	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	0.40383929267397967	[26]	[197]	4	hSpCas9	negative selection	12163232
134308354	134308377	5	-	28162770	OCIAML2	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	0.5293701747578388	[58]	[471]	5	hSpCas9	negative selection	12163233
134359908	134359931	5	+	28162770	OCIAML2	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	1.2934409990866427	[28]	[393]	9	hSpCas9	negative selection	12163234
134321860	134321883	5	-	28162770	OCIAML2	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	-0.8076648125197319	[5]	[18]	-5	hSpCas9	negative selection	12163235
134321837	134321860	5	+	28162770	OCIAML2	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-0.5598971633392484	[24]	[93]	-4	hSpCas9	negative selection	12163236
134308248	134308271	5	+	28162770	OCIAML2	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	1.276604104377872	[41]	[563]	9	hSpCas9	negative selection	12163237
134366501	134366524	5	-	28162770	OCIAML2	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.05453959063673741	[77]	[448]	0	hSpCas9	negative selection	12163238
134366477	134366500	5	-	28162770	OCIAML2	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	0.11433267547899506	[9]	[59]	1	hSpCas9	negative selection	12163239
134350325	134350348	5	-	28162770	OCIAML2	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.09415479354136469	[59]	[354]	0	hSpCas9	negative selection	12163240
134319371	134319394	5	+	28162770	OCIAML2	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	0.10162162372944106	[56]	[338]	1	hSpCas9	negative selection	12163241
134308225	134308248	5	-	28162770	OCIAML3	viability	AAAGAAAATCCACATTGCGGAGG	CDKL3	ENSG00000006837	1.277005918955759	[37]	[277]	9	hSpCas9	negative selection	12332598
134308354	134308377	5	-	28162770	OCIAML3	viability	AAAGAGTATGAAGGTGGACTTGG	CDKL3	ENSG00000006837	1.1358284897839381	[70]	[470]	8	hSpCas9	negative selection	12332599
134359908	134359931	5	+	28162770	OCIAML3	viability	GAAGATAGTCAATTGCTCGAAGG	CDKL3	ENSG00000006837	0.22312830252602633	[62]	[221]	2	hSpCas9	negative selection	12332600
134321860	134321883	5	-	28162770	OCIAML3	viability	GGGCTGTATGATCATTGAGATGG	CDKL3	ENSG00000006837	3.2236156171872676	[4]	[140]	9	hSpCas9	negative selection	12332601
134321837	134321860	5	+	28162770	OCIAML3	viability	AGGAAGATAGGGATTTCCAGTGG	CDKL3	ENSG00000006837	-1.050865315297634	[34]	[50]	-6	hSpCas9	negative selection	12332602
134308248	134308271	5	+	28162770	OCIAML3	viability	CAAGCCATTACAGTTAGTGCTGG	CDKL3	ENSG00000006837	-0.34287532354666095	[70]	[168]	-3	hSpCas9	negative selection	12332603
134366501	134366524	5	-	28162770	OCIAML3	viability	ATGGAGATGTATGAAACCCTTGG	CDKL3	ENSG00000006837	0.8461963053358085	[102]	[558]	7	hSpCas9	negative selection	12332604
134366477	134366500	5	-	28162770	OCIAML3	viability	AAAGTGGGAGAGGGAAGTTACGG	CDKL3	ENSG00000006837	1.1820963477490012	[19]	[136]	8	hSpCas9	negative selection	12332605
134350325	134350348	5	-	28162770	OCIAML3	viability	ACGAACACTAGCAGCTCCTGGGG	CDKL3	ENSG00000006837	0.12422139126045728	[92]	[305]	1	hSpCas9	negative selection	12332606
134319371	134319394	5	+	28162770	OCIAML3	viability	GCCAACAATCCATTAAGCTTTGG	CDKL3	ENSG00000006837	-0.33766788706437767	[107]	[257]	-3	hSpCas9	negative selection	12332607