Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:344387
• Symbol:CDKL4
• Description:cyclin dependent kinase like 4

DataSource: http://genomecrispr.dkfz.de/#!/results/CDKL4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
39225924	39225947	2	-	26472758	Jiyoye	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.7352295791900776	[375]	[471]	5	hSpCas9	negative selection	28951
39184608	39184631	2	-	26472758	Jiyoye	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	-0.4389119350404451	[452]	[251]	-3	hSpCas9	negative selection	28952
39190335	39190358	2	-	26472758	Jiyoye	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.6798599573733866	[148]	[179]	5	hSpCas9	negative selection	28953
39184590	39184613	2	-	26472758	Jiyoye	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	-0.1833681514785822	[258]	[171]	-1	hSpCas9	negative selection	28954
39187638	39187661	2	+	26472758	Jiyoye	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.5120177473633716	[198]	[213]	4	hSpCas9	negative selection	28955
39190468	39190491	2	+	26472758	Jiyoye	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.826631552051722	[325]	[435]	6	hSpCas9	negative selection	28956
39190430	39190453	2	+	26472758	Jiyoye	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.19190739460280687	[100]	[86]	1	hSpCas9	negative selection	28957
39190349	39190372	2	-	26472758	Jiyoye	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	1.1493776240382267	[54]	[91]	7	hSpCas9	negative selection	28958
39229437	39229460	2	+	26472758	Jiyoye	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.3225129844364891	[385]	[363]	2	hSpCas9	negative selection	28959
39213461	39213484	2	-	26472758	Jiyoye	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.5969999403858905	[127]	[145]	4	hSpCas9	negative selection	28960
39225924	39225947	2	-	26472758	KBM7	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.543664047413984	[1675,1118]	[1009,882]	6	hSpCas9	negative selection	220069
39184608	39184631	2	-	26472758	KBM7	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.3540873220892218	[1331,1392]	[905,751]	4	hSpCas9	negative selection	220070
39190335	39190358	2	-	26472758	KBM7	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	-0.13985367837397644	[534,513]	[262,189]	-1	hSpCas9	negative selection	220071
39184590	39184613	2	-	26472758	KBM7	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.5280361259484357	[753,763]	[593,448]	6	hSpCas9	negative selection	220072
39187638	39187661	2	+	26472758	KBM7	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.814899541122949	[682,556]	[613,416]	8	hSpCas9	negative selection	220073
39190468	39190491	2	+	26472758	KBM7	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.3759020034401408	[1736,1202]	[1146,649]	4	hSpCas9	negative selection	220074
39190430	39190453	2	+	26472758	KBM7	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.3139219324619884	[581,555]	[353,314]	3	hSpCas9	negative selection	220075
39190349	39190372	2	-	26472758	KBM7	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.7708188552070643	[601,316]	[325,387]	8	hSpCas9	negative selection	220076
39229437	39229460	2	+	26472758	KBM7	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.31842648674273044	[1571,1461]	[777,990]	3	hSpCas9	negative selection	220077
39213461	39213484	2	-	26472758	KBM7	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.4499921205860643	[705,599]	[257,560]	5	hSpCas9	negative selection	220078
39225924	39225947	2	-	26472758	Raji	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.6243006486716569	[614]	[219]	6	hSpCas9	negative selection	411187
39184608	39184631	2	-	26472758	Raji	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.2956031649352002	[652]	[185]	3	hSpCas9	negative selection	411188
39190335	39190358	2	-	26472758	Raji	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.06730609599826437	[291]	[70]	0	hSpCas9	negative selection	411189
39184590	39184613	2	-	26472758	Raji	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.17879786866576197	[334]	[87]	1	hSpCas9	negative selection	411190
39187638	39187661	2	+	26472758	Raji	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	1.080110605223496	[266]	[130]	8	hSpCas9	negative selection	411191
39190468	39190491	2	+	26472758	Raji	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	-0.13824119220056574	[625]	[131]	-1	hSpCas9	negative selection	411192
39190430	39190453	2	+	26472758	Raji	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.10738353537359963	[311]	[77]	1	hSpCas9	negative selection	411193
39190349	39190372	2	-	26472758	Raji	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.7479807350675742	[194]	[75]	7	hSpCas9	negative selection	411194
39229437	39229460	2	+	26472758	Raji	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.0351552078184203	[941]	[223]	0	hSpCas9	negative selection	411195
39213461	39213484	2	-	26472758	Raji	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	1.229555405367544	[214]	[116]	9	hSpCas9	negative selection	411196
39225924	39225947	2	-	26472758	K562	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.17913745676655268	[1310]	[1252]	1	hSpCas9	negative selection	602305
39184608	39184631	2	-	26472758	K562	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.31262728376928806	[1197]	[1255]	2	hSpCas9	negative selection	602306
39190335	39190358	2	-	26472758	K562	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.09808438430808891	[507]	[458]	0	hSpCas9	negative selection	602307
39184590	39184613	2	-	26472758	K562	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.4122959004599005	[704]	[791]	3	hSpCas9	negative selection	602308
39187638	39187661	2	+	26472758	K562	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.47065117001071344	[535]	[626]	4	hSpCas9	negative selection	602309
39190468	39190491	2	+	26472758	K562	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.11513571072148032	[1259]	[1151]	0	hSpCas9	negative selection	602310
39190430	39190453	2	+	26472758	K562	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	-0.7846823917343192	[650]	[318]	-4	hSpCas9	negative selection	602311
39190349	39190372	2	-	26472758	K562	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	1.3190367690130316	[291]	[614]	9	hSpCas9	negative selection	602312
39229437	39229460	2	+	26472758	K562	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.36760626792568263	[1425]	[932]	-2	hSpCas9	negative selection	602313
39213461	39213484	2	-	26472758	K562	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.45039338956893227	[605]	[698]	3	hSpCas9	negative selection	602314
39178697	39178720	2	-	26627737	DLD1	viability	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.4018694207081539	[1157]	[598,606,266]	4	hSpCas9	negative selection	811920
39179265	39179288	2	+	26627737	DLD1	viability	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.17222429540620499	[330]	[130,100,116]	1	hSpCas9	negative selection	811921
39187626	39187649	2	-	26627737	DLD1	viability	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-0.3364306134892391	[402]	[145,96,61]	-3	hSpCas9	negative selection	811922
39190462	39190485	2	-	26627737	DLD1	viability	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.841778929234005	[431]	[140,348,240]	7	hSpCas9	negative selection	811923
39178697	39178720	2	-	26627737	GBM cells	viability after 5 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.29300831434393637	[849]	[531,584]	4	hSpCas9	negative selection	894235
39179265	39179288	2	+	26627737	GBM cells	viability after 5 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.5713392168571814	[255]	[229,177]	8	hSpCas9	negative selection	894236
39187626	39187649	2	-	26627737	GBM cells	viability after 5 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.3524255219791651	[221]	[138,164]	5	hSpCas9	negative selection	894237
39190462	39190485	2	-	26627737	GBM cells	viability after 5 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.17287680818232454	[411]	[216,174]	-3	hSpCas9	negative selection	894238
39178697	39178720	2	-	26627737	GBM cells	viability after 13 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.14368078709067422	[849]	[514,504]	1	hSpCas9	negative selection	976550
39179265	39179288	2	+	26627737	GBM cells	viability after 13 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.3509068259111007	[255]	[196,160]	4	hSpCas9	negative selection	976551
39187626	39187649	2	-	26627737	GBM cells	viability after 13 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.987088611097727	[221]	[235,240]	9	hSpCas9	negative selection	976552
39190462	39190485	2	-	26627737	GBM cells	viability after 13 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.4763825371571161	[411]	[206,122]	-5	hSpCas9	negative selection	976553
39178697	39178720	2	-	26627737	GBM cells	viability after 21 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	-0.11310609874872024	[849]	[415,436]	-1	hSpCas9	negative selection	1058865
39179265	39179288	2	+	26627737	GBM cells	viability after 21 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.5088611017758081	[255]	[211,184]	5	hSpCas9	negative selection	1058866
39187626	39187649	2	-	26627737	GBM cells	viability after 21 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.5983603883624121	[221]	[191,173]	6	hSpCas9	negative selection	1058867
39190462	39190485	2	-	26627737	GBM cells	viability after 21 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.05249334571480002	[411]	[207,222]	0	hSpCas9	negative selection	1058868
39178697	39178720	2	-	26627737	RPE1	viability after 9 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.8091600269252373	[2630]	[1351,1560]	5	hSpCas9	negative selection	1141180
39179265	39179288	2	+	26627737	RPE1	viability after 9 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	1.168683618061557	[330]	[180,299]	7	hSpCas9	negative selection	1141181
39187626	39187649	2	-	26627737	RPE1	viability after 9 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	1.1441291410624594	[331]	[306,129]	7	hSpCas9	negative selection	1141182
39190462	39190485	2	-	26627737	RPE1	viability after 9 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.6487787887790457	[1318]	[172,379]	-5	hSpCas9	negative selection	1141183
39178697	39178720	2	-	26627737	RPE1	viability after 12 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.9863391300483906	[2630]	[1396,1403]	6	hSpCas9	negative selection	1223495
39179265	39179288	2	+	26627737	RPE1	viability after 12 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	1.174218117456312	[330]	[121,283]	7	hSpCas9	negative selection	1223496
39187626	39187649	2	-	26627737	RPE1	viability after 12 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	1.6404578031043824	[331]	[416,130]	8	hSpCas9	negative selection	1223497
39190462	39190485	2	-	26627737	RPE1	viability after 12 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.3964297261502525	[1318]	[242,296]	-3	hSpCas9	negative selection	1223498
39178697	39178720	2	-	26627737	RPE1	viability after 15 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.8838495667426234	[2630]	[1577,1175]	5	hSpCas9	negative selection	1305810
39179265	39179288	2	+	26627737	RPE1	viability after 15 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	1.585406474988845	[330]	[84,469]	8	hSpCas9	negative selection	1305811
39187626	39187649	2	-	26627737	RPE1	viability after 15 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	1.7471396537990254	[331]	[468,166]	8	hSpCas9	negative selection	1305812
39190462	39190485	2	-	26627737	RPE1	viability after 15 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.20829174109302862	[1318]	[212,428]	-1	hSpCas9	negative selection	1305813
39178697	39178720	2	-	26627737	RPE1	viability after 18 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.8942685729896536	[2630]	[1616,1001]	5	hSpCas9	negative selection	1388125
39179265	39179288	2	+	26627737	RPE1	viability after 18 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	1.3590502554560944	[330]	[101,364]	7	hSpCas9	negative selection	1388126
39187626	39187649	2	-	26627737	RPE1	viability after 18 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	1.5312523095431883	[331]	[359,150]	7	hSpCas9	negative selection	1388127
39190462	39190485	2	-	26627737	RPE1	viability after 18 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.22842049319740587	[1318]	[196,417]	-1	hSpCas9	negative selection	1388128
39178697	39178720	2	-	26627737	HeLa	viability after 8 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.3147360712776113	[1310]	[867,667,632]	3	hSpCas9	negative selection	1470440
39179265	39179288	2	+	26627737	HeLa	viability after 8 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.07773743813060208	[552]	[336,127,310]	0	hSpCas9	negative selection	1470441
39187626	39187649	2	-	26627737	HeLa	viability after 8 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-1.1030897991848065	[414]	[60,129,57]	-8	hSpCas9	negative selection	1470442
39190462	39190485	2	-	26627737	HeLa	viability after 8 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-1.3078493176311765	[834]	[107,76,239]	-8	hSpCas9	negative selection	1470443
39178697	39178720	2	-	26627737	HeLa	viability after 12 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.36785865501129456	[1310]	[928,822,338]	3	hSpCas9	negative selection	1552755
39179265	39179288	2	+	26627737	HeLa	viability after 12 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.3079143001183603	[552]	[196,218,436]	2	hSpCas9	negative selection	1552756
39187626	39187649	2	-	26627737	HeLa	viability after 12 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-1.6346461495392155	[414]	[48,78,34]	-9	hSpCas9	negative selection	1552757
39190462	39190485	2	-	26627737	HeLa	viability after 12 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.8848206174155682	[834]	[144,237,170]	-7	hSpCas9	negative selection	1552758
39178697	39178720	2	-	26627737	HeLa	viability after 15 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.008951429348291295	[1310]	[552,579,472]	0	hSpCas9	negative selection	1635070
39179265	39179288	2	+	26627737	HeLa	viability after 15 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.3873159609333715	[552]	[250,228,412]	3	hSpCas9	negative selection	1635071
39187626	39187649	2	-	26627737	HeLa	viability after 15 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-0.6796043286421197	[414]	[46,154,115]	-5	hSpCas9	negative selection	1635072
39190462	39190485	2	-	26627737	HeLa	viability after 15 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.7078695808166571	[834]	[227,188,206]	-6	hSpCas9	negative selection	1635073
39178697	39178720	2	-	26627737	HeLa	viability after 18 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	-0.030316037136989493	[1310]	[343,478,472]	0	hSpCas9	negative selection	1717385
39179265	39179288	2	+	26627737	HeLa	viability after 18 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.3819985877690013	[552]	[169,184,412]	3	hSpCas9	negative selection	1717386
39187626	39187649	2	-	26627737	HeLa	viability after 18 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-0.6839044814997753	[414]	[27,131,115]	-6	hSpCas9	negative selection	1717387
39190462	39190485	2	-	26627737	HeLa	viability after 18 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.7748997317961885	[834]	[138,150,206]	-6	hSpCas9	negative selection	1717388
39178697	39178720	2	-	26627737	HCT116	viability after 6 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.9900476406147605	[1648]	[414,569]	5	hSpCas9	negative selection	1799700
39179265	39179288	2	+	26627737	HCT116	viability after 6 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.06878839837248041	[811]	[13,199]	0	hSpCas9	negative selection	1799701
39187626	39187649	2	-	26627737	HCT116	viability after 6 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-2.261902410536963	[618]	[18,20]	-8	hSpCas9	negative selection	1799702
39190462	39190485	2	-	26627737	HCT116	viability after 6 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	1.0932705269180205	[609]	[56,285]	6	hSpCas9	negative selection	1799703
39178697	39178720	2	-	26627737	HCT116	viability after 8 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.3286001194823607	[798]	[424,646,583]	3	hSpCas9	negative selection	1882015
39179265	39179288	2	+	26627737	HCT116	viability after 8 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	-0.18923501302113926	[318]	[137,151,171]	-2	hSpCas9	negative selection	1882016
39187626	39187649	2	-	26627737	HCT116	viability after 8 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.7015071898656109	[174]	[170,167,131]	6	hSpCas9	negative selection	1882017
39190462	39190485	2	-	26627737	HCT116	viability after 8 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.730172208867985	[323]	[332,331,224]	7	hSpCas9	negative selection	1882018
39178697	39178720	2	-	26627737	HCT116	viability after 9 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.5139103008159649	[1648]	[244,931]	4	hSpCas9	negative selection	1964330
39179265	39179288	2	+	26627737	HCT116	viability after 9 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	-0.6394427545027143	[811]	[165,117]	-4	hSpCas9	negative selection	1964331
39187626	39187649	2	-	26627737	HCT116	viability after 9 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-0.1682495470031005	[618]	[274,45]	-1	hSpCas9	negative selection	1964332
39190462	39190485	2	-	26627737	HCT116	viability after 9 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.39342691032178234	[609]	[285,156]	3	hSpCas9	negative selection	1964333
39178697	39178720	2	-	26627737	HCT116	viability after 12 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.3546316999192356	[798]	[301,728,604]	3	hSpCas9	negative selection	2046645
39179265	39179288	2	+	26627737	HCT116	viability after 12 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	-0.2198722160399449	[318]	[103,170,160]	-2	hSpCas9	negative selection	2046646
39187626	39187649	2	-	26627737	HCT116	viability after 12 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.3787310487661289	[174]	[63,176,123]	4	hSpCas9	negative selection	2046647
39190462	39190485	2	-	26627737	HCT116	viability after 12 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.735677375994653	[323]	[226,342,286]	6	hSpCas9	negative selection	2046648
39178697	39178720	2	-	26627737	HCT116	viability after 15 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.4348006449841524	[798]	[535,568,743]	4	hSpCas9	negative selection	2128960
39179265	39179288	2	+	26627737	HCT116	viability after 15 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	-0.2574396910675842	[318]	[180,115,165]	-3	hSpCas9	negative selection	2128961
39187626	39187649	2	-	26627737	HCT116	viability after 15 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.5836075596237247	[174]	[186,179,89]	5	hSpCas9	negative selection	2128962
39190462	39190485	2	-	26627737	HCT116	viability after 15 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.5296412638304518	[323]	[311,221,276]	5	hSpCas9	negative selection	2128963
39178697	39178720	2	-	26627737	HCT116	viability after 18 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.31038257604406394	[798]	[281,576,575]	2	hSpCas9	negative selection	2211275
39179265	39179288	2	+	26627737	HCT116	viability after 18 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	-0.6928032229897378	[318]	[93,37,160]	-6	hSpCas9	negative selection	2211276
39187626	39187649	2	-	26627737	HCT116	viability after 18 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.39952864004089966	[174]	[80,130,121]	3	hSpCas9	negative selection	2211277
39190462	39190485	2	-	26627737	HCT116	viability after 18 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.6955315383015601	[323]	[245,256,257]	6	hSpCas9	negative selection	2211278
39190478	39190501	2	+	24336569	HL60	viability	TAATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.3307591674980678	[897]	[2389]	3	hSpCas9	negative selection	2256809
39204543	39204566	2	-	24336569	HL60	viability	TAATCAAGATTTGTGACTTCGGG	CDKL4	ENSG00000205111	-0.4110322577183907	[425]	[677]	-4	hSpCas9	negative selection	2256810
39204568	39204591	2	-	24336569	HL60	viability	AATATTCTAATAACTAAGCAAGG	CDKL4	ENSG00000205111	1.169532511460734	[345]	[1646]	8	hSpCas9	negative selection	2256811
39225824	39225847	2	+	24336569	HL60	viability	TTCCAGATTACTTACCCATTTGG	CDKL4	ENSG00000205111	0.7376479937920762	[837]	[2956]	6	hSpCas9	negative selection	2256812
39225912	39225935	2	+	24336569	HL60	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.20941520462482197	[572]	[1401]	2	hSpCas9	negative selection	2256813
39225924	39225947	2	-	24336569	HL60	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.1694974729043225	[349]	[832]	1	hSpCas9	negative selection	2256814
39229364	39229387	2	-	24336569	HL60	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.7675656121492604	[1044]	[1298]	-6	hSpCas9	negative selection	2256815
39229437	39229460	2	+	24336569	HL60	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.5757648784323933	[423]	[601]	-5	hSpCas9	negative selection	2256816
39229485	39229508	2	-	24336569	HL60	viability	AGACTGGAGAAGGGTCTTATGGG	CDKL4	ENSG00000205111	-0.11870529277376844	[568]	[1108]	-1	hSpCas9	negative selection	2256817
39229494	39229517	2	-	24336569	HL60	viability	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	0.5502111452605882	[627]	[1945]	5	hSpCas9	negative selection	2256818
39190478	39190501	2	+	24336569	KBM7	viability	TAATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	-0.12957324736915643	[662]	[1652]	-1	hSpCas9	negative selection	2323986
39204543	39204566	2	-	24336569	KBM7	viability	TAATCAAGATTTGTGACTTCGGG	CDKL4	ENSG00000205111	2.157586874895455	[129]	[1581]	9	hSpCas9	negative selection	2323987
39204568	39204591	2	-	24336569	KBM7	viability	AATATTCTAATAACTAAGCAAGG	CDKL4	ENSG00000205111	1.598333282929608	[258]	[2138]	9	hSpCas9	negative selection	2323988
39225824	39225847	2	+	24336569	KBM7	viability	TTCCAGATTACTTACCCATTTGG	CDKL4	ENSG00000205111	0.839170760513386	[630]	[3078]	7	hSpCas9	negative selection	2323989
39225912	39225935	2	+	24336569	KBM7	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.5148324674584637	[493]	[942]	-4	hSpCas9	negative selection	2323990
39225924	39225947	2	-	24336569	KBM7	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.18823651965645394	[510]	[1587]	1	hSpCas9	negative selection	2323991
39229364	39229387	2	-	24336569	KBM7	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.8397398614083385	[539]	[2635]	7	hSpCas9	negative selection	2323992
39229437	39229460	2	+	24336569	KBM7	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.7067301678954482	[370]	[619]	-5	hSpCas9	negative selection	2323993
39229485	39229508	2	-	24336569	KBM7	viability	AGACTGGAGAAGGGTCTTATGGG	CDKL4	ENSG00000205111	1.0158213242913603	[230]	[1273]	8	hSpCas9	negative selection	2323994
39229494	39229517	2	-	24336569	KBM7	viability	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	0.4534957474837152	[463]	[1732]	4	hSpCas9	negative selection	2323995
39195684	39195707	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCACCACTACACTCCAGCCCAG	CDKL4	ENSG00000205111	1.5534549579245929	[63,822]	[25,576]	6	dCas9-VP64	positive selection	2395530
39196869	39196892	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTGTTGGGATTACAGGCGTAAG	CDKL4	ENSG00000205111	2.32900186243451	[2,3]	[4,1]	7	dCas9-VP64	positive selection	2408244
39205524	39205547	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGCAGATCACGCGG	CDKL4	ENSG00000205111	1.6160323087037833	[141,31]	[85,27]	6	dCas9-VP64	positive selection	2418286
39176574	39176597	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCATGCCCAG	CDKL4	ENSG00000205111	-2.540049325425791	[4,100]	[0,1]	-9	dCas9-VP64	positive selection	2419142
39176557	39176580	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTTGG	CDKL4	ENSG00000205111	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454671
39183029	39183052	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGCACTTTGGGAGGCCTAGG	CDKL4	ENSG00000205111	1.206940593226964	[3,2]	[1,0]	5	dCas9-VP64	positive selection	2475665
39195684	39195707	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCACCACTACACTCCAGCCCAG	CDKL4	ENSG00000205111	-0.4021395541078192	[270,438]	[81,91]	-4	dCas9-VP64	positive selection	2490785
39196869	39196892	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTGTTGGGATTACAGGCGTAAG	CDKL4	ENSG00000205111	-0.3752571813335419	[45,18]	[9,5]	-4	dCas9-VP64	positive selection	2503499
39205524	39205547	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGCAGATCACGCGG	CDKL4	ENSG00000205111	0.03329666584269164	[29,118]	[13,33]	0	dCas9-VP64	positive selection	2513541
39176574	39176597	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCATGCCCAG	CDKL4	ENSG00000205111	0.03661325214909955	[138,24]	[31,22]	0	dCas9-VP64	positive selection	2514397
39176557	39176580	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTTGG	CDKL4	ENSG00000205111	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549926
39183029	39183052	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGCACTTTGGGAGGCCTAGG	CDKL4	ENSG00000205111	0.18562790618715352	[12,24]	[5,7]	1	dCas9-VP64	positive selection	2570920
39225924	39225947	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.6280460803148035	[3,3]	[2,0]	-7	hSpCas9	positive selection	2978249
39229438	39229461	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.21321312786938074	[3,3]	[1,2]	-3	hSpCas9	positive selection	2978250
39229494	39229517	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	-0.44606909646502035	[4,3]	[2,1]	-6	hSpCas9	positive selection	2978251
39225838	39225861	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCTGGAAAGAAACCCAAATGGG	CDKL4	ENSG00000205111	-0.051580444576887055	[3,3]	[3,1]	0	hSpCas9	positive selection	2978252
39225924	39225947	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.06440978329689598	[3,3]	[4,0]	-1	hSpCas9	positive selection	3046107
39229438	39229461	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.07114698363076336	[3,3]	[2,2]	1	hSpCas9	positive selection	3046108
39229494	39229517	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	-0.34335680524719897	[4,4]	[4,0]	-5	hSpCas9	positive selection	3046109
39225838	39225861	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCTGGAAAGAAACCCAAATGGG	CDKL4	ENSG00000205111	-0.3119704593709819	[3,3]	[3,0]	-5	hSpCas9	positive selection	3046110
39225924	39225947		-	24336571	A375	resistance to PLX after 7 days	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.006075274084521659	[13,13]	[16,10]	0	hSpCas9	positive selection	3104672
39229437	39229460		+	24336571	A375	resistance to PLX after 7 days	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.015046435555386484	[13,12]	[12,13]	0	hSpCas9	positive selection	3104674
39229364	39229387		-	24336571	A375	resistance to PLX after 7 days	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.04682418991670262	[11,9]	[10,9]	-1	hSpCas9	positive selection	3104675
39229387	39229410		+	24336571	A375	resistance to PLX after 7 days	AGTGCTATTTTCTTAACAACAGG	CDKL4	ENSG00000205111	0.5119989009866768	[3,6]	[6,8]	9	hSpCas9	positive selection	3104676
39225924	39225947		-	24336571	A375	resistance to PLX after 14 days	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.07536154440480441	[15,13]	[4,6]	-1	hSpCas9	positive selection	3162465
39229437	39229460		+	24336571	A375	resistance to PLX after 14 days	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.35058356006066116	[12,12]	[3,3]	-4	hSpCas9	positive selection	3162467
39229364	39229387		-	24336571	A375	resistance to PLX after 14 days	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.2306057199194061	[7,13]	[4,3]	-2	hSpCas9	positive selection	3162468
39229387	39229410		+	24336571	A375	resistance to PLX after 14 days	AGTGCTATTTTCTTAACAACAGG	CDKL4	ENSG00000205111	1.5259770935683101	[7,4]	[9,7]	9	hSpCas9	positive selection	3162469
39225924	39225947		-	24336571	A375	viability after 7 days	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.13909015925555712	[12]	[13,13]	2	hSpCas9	negative selection	3220258
39229437	39229460		+	24336571	A375	viability after 7 days	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.30671146170541624	[17]	[13,12]	-4	hSpCas9	negative selection	3220260
39229364	39229387		-	24336571	A375	viability after 7 days	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.26865546706163373	[8]	[11,9]	4	hSpCas9	negative selection	3220261
39229387	39229410		+	24336571	A375	viability after 7 days	AGTGCTATTTTCTTAACAACAGG	CDKL4	ENSG00000205111	-0.9612050872851647	[11]	[3,6]	-8	hSpCas9	negative selection	3220262
39225924	39225947		-	24336571	A375	viability after 14 days	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.24609498605209096	[12]	[15,13]	3	hSpCas9	negative selection	3278051
39229437	39229460		+	24336571	A375	viability after 14 days	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.33778742229339886	[17]	[12,12]	-4	hSpCas9	negative selection	3278053
39229364	39229387		-	24336571	A375	viability after 14 days	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.3191373973527099	[8]	[7,13]	4	hSpCas9	negative selection	3278054
39229387	39229410		+	24336571	A375	viability after 14 days	AGTGCTATTTTCTTAACAACAGG	CDKL4	ENSG00000205111	-0.7282308557159293	[11]	[7,4]	-7	hSpCas9	negative selection	3278055
39225924	39225947	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.4601038172489684	[204,215]	[0,0]	-3	hSpCas9	positive selection	3342456
39225912	39225935	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.40629002587486596	[241,162]	[0,0]	-3	hSpCas9	positive selection	3342457
39229437	39229460	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.4755672212218343	[247,176]	[0,0]	-3	hSpCas9	positive selection	3342458
39229364	39229387	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.22390320990838475	[130,130]	[0,0]	1	hSpCas9	positive selection	3361690
39229424	39229447	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.18051061439500407	[134,134]	[0,0]	1	hSpCas9	positive selection	3361691
39229453	39229476	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	1.2129320920873818	[65,65]	[0,0]	5	hSpCas9	positive selection	3361692
39225924	39225947	2	-	26780180	HT29	viability (Avana library 4 designs)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	1.25896258509267	[]	[]	5	hSpCas9	negative selection	3414562
39229437	39229460	2	+	26780180	HT29	viability (Avana library 4 designs)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	1.29726645557608	[]	[]	5	hSpCas9	negative selection	3414563
39229494	39229517	2	-	26780180	HT29	viability (Avana library 4 designs)	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	0.0827963853867504	[]	[]	0	hSpCas9	negative selection	3414564
39225838	39225861	2	-	26780180	HT29	viability (Avana library 4 designs)	AGCTGGAAAGAAACCCAAATGGG	CDKL4	ENSG00000205111	0.136567152707733	[]	[]	0	hSpCas9	negative selection	3414565
39229494	39229517	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	-0.536042947966041	[]	[]	0	hSpCas9	negative selection	3491140
39225924	39225947	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.12189779801858	[]	[]	0	hSpCas9	negative selection	3491141
39229437	39229460	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.122651598053661	[]	[]	0	hSpCas9	negative selection	3491142
39225838	39225861	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTGGAAAGAAACCCAAATGGG	CDKL4	ENSG00000205111	-1.02565732053131	[]	[]	-1	hSpCas9	negative selection	3491143
39225912	39225935	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.77722442642133	[]	[]	-1	hSpCas9	negative selection	3491144
39229484	39229507	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACTGGAGAAGGGTCTTATGGGG	CDKL4	ENSG00000205111	5.19361209522744	[]	[]	8	hSpCas9	negative selection	3491145
39229494	39229517	2	-	26780180	A375	viability (Avana lentiGuide)	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	-3.99603326610273	[]	[]	-7	hSpCas9	negative selection	3599799
39225924	39225947	2	-	26780180	A375	viability (Avana lentiGuide)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	4.58551821893513	[]	[]	4	hSpCas9	negative selection	3599800
39229437	39229460	2	+	26780180	A375	viability (Avana lentiGuide)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	6.61680448383999	[]	[]	5	hSpCas9	negative selection	3599801
39225838	39225861	2	-	26780180	A375	viability (Avana lentiGuide)	AGCTGGAAAGAAACCCAAATGGG	CDKL4	ENSG00000205111	-4.0644168229675	[]	[]	-7	hSpCas9	negative selection	3599802
39225912	39225935	2	+	26780180	A375	viability (Avana lentiGuide)	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-1.66757731574012	[]	[]	-3	hSpCas9	negative selection	3599803
39229484	39229507	2	-	26780180	A375	viability (Avana lentiGuide)	GACTGGAGAAGGGTCTTATGGGG	CDKL4	ENSG00000205111	-3.7462473512171	[]	[]	-6	hSpCas9	negative selection	3599804
39229494	39229517	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	-0.01746642911633528	[6]	[7,5]	0	hSpCas9	positive selection	3708458
39225924	39225947	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.00484572039379709	[5]	[5,4]	0	hSpCas9	positive selection	3708459
39229437	39229460	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.04079600353748328	[5]	[5,4]	0	hSpCas9	positive selection	3708460
39225838	39225861	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTGGAAAGAAACCCAAATGGG	CDKL4	ENSG00000205111	-0.056217354740570526	[4]	[5,3]	-1	hSpCas9	positive selection	3708461
39225912	39225935	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.05137390615322768	[5]	[5,5]	1	hSpCas9	positive selection	3708462
39229484	39229507	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTGGAGAAGGGTCTTATGGGG	CDKL4	ENSG00000205111	0.21983231125102892	[5]	[6,6]	6	hSpCas9	positive selection	3708463
39229494	39229517	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATTAGCTAAGACTGGAGAAGGG	CDKL4	ENSG00000205111	0.19508296698201613	[5]	[5,4]	5	hSpCas9	positive selection	3817065
39225924	39225947	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.3281545225456648	[4]	[3,1]	-4	hSpCas9	positive selection	3817066
39229437	39229460	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.2140135194584228	[5]	[2,4]	-3	hSpCas9	positive selection	3817067
39225838	39225861	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTGGAAAGAAACCCAAATGGG	CDKL4	ENSG00000205111	0.43136687943078267	[4]	[5,5]	9	hSpCas9	positive selection	3817068
39225912	39225935	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.07280937545788131	[5]	[4,5]	1	hSpCas9	positive selection	3817069
39229484	39229507	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTGGAGAAGGGTCTTATGGGG	CDKL4	ENSG00000205111	0.2905630197780261	[6]	[7,6]	7	hSpCas9	positive selection	3817070
39225924	39225947	2	-	26780180	A375	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	1.09596787461592	[]	[]	5	hSpCas9	negative selection	3925247
39229453	39229476	2	-	26780180	A375	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	1.11840710045293	[]	[]	5	hSpCas9	negative selection	3925248
39229437	39229460	2	+	26780180	A375	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.980974170487515	[]	[]	4	hSpCas9	negative selection	3925249
39229364	39229387	2	-	26780180	A375	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	1.26399084789212	[]	[]	6	hSpCas9	negative selection	3925250
39229424	39229447	2	-	26780180	A375	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	-0.0166987448940433	[]	[]	0	hSpCas9	negative selection	3925251
39225912	39225935	2	+	26780180	A375	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.707398528403619	[]	[]	2	hSpCas9	negative selection	3925252
39225924	39225947	2	-	26780180	HT29	viability (GeCKOv2 library)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.706892908042524	[]	[]	2	hSpCas9	negative selection	4033213
39229453	39229476	2	-	26780180	HT29	viability (GeCKOv2 library)	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.875195482148588	[]	[]	3	hSpCas9	negative selection	4033214
39229437	39229460	2	+	26780180	HT29	viability (GeCKOv2 library)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	1.18501636411767	[]	[]	6	hSpCas9	negative selection	4033215
39229364	39229387	2	-	26780180	HT29	viability (GeCKOv2 library)	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	1.03406576241229	[]	[]	5	hSpCas9	negative selection	4033216
39229424	39229447	2	-	26780180	HT29	viability (GeCKOv2 library)	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	1.01938277432738	[]	[]	4	hSpCas9	negative selection	4033217
39225912	39225935	2	+	26780180	HT29	viability (GeCKOv2 library)	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.325504180495751	[]	[]	0	hSpCas9	negative selection	4033218
39225924	39225947	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.1080740559452118	[4]	[2,2]	-3	hSpCas9	positive selection	4126701
39229437	39229460	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.38498649242070865	[3]	[5,1]	8	hSpCas9	positive selection	4126703
39229364	39229387	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.06981397551411495	[3]	[2,1]	-2	hSpCas9	positive selection	4126704
39229387	39229410	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTGCTATTTTCTTAACAACAGG	CDKL4	ENSG00000205111	0.8981462231338551	[2]	[3,3]	9	hSpCas9	positive selection	4126705
39225924	39225947	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.5585618705758209	[3]	[1,0,0,0]	-7	hSpCas9	positive selection	4190723
39229437	39229460	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.24855635719854346	[3]	[4,2,1,0]	2	hSpCas9	positive selection	4190725
39229364	39229387	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.11929743553515185	[3]	[3,1,1,0]	-2	hSpCas9	positive selection	4190726
39229387	39229410	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTGCTATTTTCTTAACAACAGG	CDKL4	ENSG00000205111	0.3245835570041575	[3]	[0,2,4,0]	2	hSpCas9	positive selection	4190727
39225924	39225947	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.09807806226167703	[4]	[3,2]	2	hSpCas9	positive selection	4262512
39225912	39225935	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.20602990959693757	[3]	[4,2]	4	hSpCas9	positive selection	4262513
39229437	39229460	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.1287205024449057	[3]	[3,2]	2	hSpCas9	positive selection	4262514
39229364	39229387	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.10107087640887258	[2]	[2,1]	2	hSpCas9	positive selection	4326790
39229424	39229447	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.5883559507938142	[2]	[3,2]	9	hSpCas9	positive selection	4326791
39229453	39229476	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.4820418517486761	[1]	[2,1]	8	hSpCas9	positive selection	4326792
39190421	39190443	2	-	27760321	OCIAML3	viability	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.5238971048458152	[97,64]	[56,133]	6	hSpCas9	negative selection	4388136
39190479	39190501	2	+	27760321	OCIAML3	viability	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	-0.4725641110163996	[545,478]	[233,358]	-5	hSpCas9	negative selection	4388137
39225907	39225929	2	-	27760321	OCIAML3	viability	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	-0.669975462141728	[104,87]	[38,57]	-6	hSpCas9	negative selection	4388138
39225924	39225946	2	-	27760321	OCIAML3	viability	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.2076779616617882	[383,401]	[272,465]	2	hSpCas9	negative selection	4388139
39229364	39229386	2	-	27760321	OCIAML3	viability	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.7230926997628391	[26,20]	[48,6]	8	hSpCas9	negative selection	4388140
39190421	39190443	2	-	27760321	OCIAML2	viability	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	1.0950904487788835	[97,64]	[122,159]	9	hSpCas9	negative selection	4471599
39190479	39190501	2	+	27760321	OCIAML2	viability	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.21806752041891306	[545,478]	[466,499]	3	hSpCas9	negative selection	4471600
39225907	39225929	2	-	27760321	OCIAML2	viability	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.9264914131642232	[104,87]	[136,161]	9	hSpCas9	negative selection	4471601
39225924	39225946	2	-	27760321	OCIAML2	viability	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.6613629121673175	[383,401]	[444,584]	8	hSpCas9	negative selection	4471602
39229364	39229386	2	-	27760321	OCIAML2	viability	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.9404462367758537	[26,20]	[36,36]	9	hSpCas9	negative selection	4471603
39190421	39190443	2	-	27760321	MV411	viability	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	1.3439221502377978	[97,64]	[13,315]	8	hSpCas9	negative selection	4555062
39190479	39190501	2	+	27760321	MV411	viability	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.028014331229666817	[545,478]	[238,501]	0	hSpCas9	negative selection	4555063
39225907	39225929	2	-	27760321	MV411	viability	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	1.5539618964031208	[104,87]	[236,109]	9	hSpCas9	negative selection	4555064
39225924	39225946	2	-	27760321	MV411	viability	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.6515306660582663	[383,401]	[105,255]	-4	hSpCas9	negative selection	4555065
39229364	39229386	2	-	27760321	MV411	viability	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.12672114911955656	[26,20]	[19,5]	-1	hSpCas9	negative selection	4555066
39190421	39190443	2	-	27760321	HL60	viability	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	1.5815549539134484	[97,64]	[116,280]	9	hSpCas9	negative selection	4638525
39190479	39190501	2	+	27760321	HL60	viability	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.04928580202964347	[545,478]	[408,456]	0	hSpCas9	negative selection	4638526
39225907	39225929	2	-	27760321	HL60	viability	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	-0.10313610318527777	[104,87]	[92,51]	-1	hSpCas9	negative selection	4638527
39225924	39225946	2	-	27760321	HL60	viability	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.07183431647623309	[383,401]	[290,323]	-1	hSpCas9	negative selection	4638528
39229364	39229386	2	-	27760321	HL60	viability	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.6188180860879369	[26,20]	[1,23]	-6	hSpCas9	negative selection	4638529
39190421	39190443	2	-	27760321	HT1080	viability	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	-0.3002783640976041	[64,50]	[34,0]	-1	hSpCas9	negative selection	4721988
39190479	39190501	2	+	27760321	HT1080	viability	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.7917676809779225	[478,373]	[370,209]	4	hSpCas9	negative selection	4721989
39225907	39225929	2	-	27760321	HT1080	viability	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	-2.118104269756827	[87,68]	[0,13]	-6	hSpCas9	negative selection	4721990
39225924	39225946	2	-	27760321	HT1080	viability	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.9469427029673366	[401,313]	[178,379]	5	hSpCas9	negative selection	4721991
39229364	39229386	2	-	27760321	HT1080	viability	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-2.9233782605522816	[20,16]	[0,0]	-7	hSpCas9	negative selection	4721992
39190421	39190443	2	-	27760321	HT29	viability after 7 days	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.5341697059114612	[64,50]	[83,112,122]	7	hSpCas9	negative selection	4805451
39190479	39190501	2	+	27760321	HT29	viability after 7 days	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	-0.08061805484837714	[478,373]	[711,493,380]	-1	hSpCas9	negative selection	4805452
39225907	39225929	2	-	27760321	HT29	viability after 7 days	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.7834933714444017	[87,68]	[204,256,66]	9	hSpCas9	negative selection	4805453
39225924	39225946	2	-	27760321	HT29	viability after 7 days	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.1733261497389457	[401,313]	[467,402,362]	-3	hSpCas9	negative selection	4805454
39229364	39229386	2	-	27760321	HT29	viability after 7 days	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-2.5818423947149993	[20,16]	[1,6,2]	-9	hSpCas9	negative selection	4805455
39190421	39190443	2	-	27760321	HT29	viability after 25 days	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.9240752710334728	[64,50]	[111,80,191]	9	hSpCas9	negative selection	4888914
39190479	39190501	2	+	27760321	HT29	viability after 25 days	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	-0.4170324883065736	[478,373]	[418,360,304]	-4	hSpCas9	negative selection	4888915
39225907	39225929	2	-	27760321	HT29	viability after 25 days	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.5766158912445065	[87,68]	[183,89,122]	6	hSpCas9	negative selection	4888916
39225924	39225946	2	-	27760321	HT29	viability after 25 days	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.3980525072414649	[401,313]	[282,362,283]	-4	hSpCas9	negative selection	4888917
39229364	39229386	2	-	27760321	HT29	viability after 25 days	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.3696081943248344	[20,16]	[2,27,57]	4	hSpCas9	negative selection	4888918
39190421	39190443	2	-	27760321	HT29	viability after 22 days	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.4442163126932317	[64,50]	[52,109,111]	5	hSpCas9	negative selection	4972377
39190479	39190501	2	+	27760321	HT29	viability after 22 days	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.30639585710208816	[478,373]	[649,368,810]	3	hSpCas9	negative selection	4972378
39225907	39225929	2	-	27760321	HT29	viability after 22 days	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	-0.24629861673836917	[87,68]	[84,104,38]	-3	hSpCas9	negative selection	4972379
39225924	39225946	2	-	27760321	HT29	viability after 22 days	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.08259934898243024	[401,313]	[565,343,400]	0	hSpCas9	negative selection	4972380
39229364	39229386	2	-	27760321	HT29	viability after 22 days	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.7579959003781678	[20,16]	[49,59,0]	8	hSpCas9	negative selection	4972381
39190421	39190443	2	-	27760321	HT29	viability after 19 days	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.18409353895813974	[64,50]	[67,72,83]	1	hSpCas9	negative selection	5055840
39190479	39190501	2	+	27760321	HT29	viability after 19 days	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	-0.35569067785331926	[478,373]	[516,377,266]	-3	hSpCas9	negative selection	5055841
39225907	39225929	2	-	27760321	HT29	viability after 19 days	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.4736929804543788	[87,68]	[153,175,49]	5	hSpCas9	negative selection	5055842
39225924	39225946	2	-	27760321	HT29	viability after 19 days	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.3776807122731119	[401,313]	[359,383,209]	-3	hSpCas9	negative selection	5055843
39229364	39229386	2	-	27760321	HT29	viability after 19 days	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.36035427945465015	[20,16]	[47,37,0]	3	hSpCas9	negative selection	5055844
39190421	39190443	2	-	27760321	HT29	viability after 16 days	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.5486458942028847	[64,50]	[32,93,151]	6	hSpCas9	negative selection	5139303
39190479	39190501	2	+	27760321	HT29	viability after 16 days	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.3524420601766063	[478,373]	[859,504,488]	4	hSpCas9	negative selection	5139304
39225907	39225929	2	-	27760321	HT29	viability after 16 days	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.2758281858215015	[87,68]	[64,188,58]	3	hSpCas9	negative selection	5139305
39225924	39225946	2	-	27760321	HT29	viability after 16 days	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.5784783547362716	[401,313]	[364,260,187]	-5	hSpCas9	negative selection	5139306
39229364	39229386	2	-	27760321	HT29	viability after 16 days	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.763638076875266	[20,16]	[81,29,0]	8	hSpCas9	negative selection	5139307
39190421	39190443	2	-	27760321	HT29	viability after 13 days	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.49181611013059356	[64,50]	[105,135,44]	6	hSpCas9	negative selection	5222766
39190479	39190501	2	+	27760321	HT29	viability after 13 days	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.12279146496387416	[478,373]	[597,546,474]	1	hSpCas9	negative selection	5222767
39225907	39225929	2	-	27760321	HT29	viability after 13 days	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.689099008079125	[87,68]	[229,73,136]	8	hSpCas9	negative selection	5222768
39225924	39225946	2	-	27760321	HT29	viability after 13 days	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.03141073837570693	[401,313]	[377,482,360]	0	hSpCas9	negative selection	5222769
39229364	39229386	2	-	27760321	HT29	viability after 13 days	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-1.0925132358521763	[20,16]	[0,0,27]	-7	hSpCas9	negative selection	5222770
39190421	39190443	2	-	27760321	HT29	viability after 10 days	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.36860829489729996	[64,50]	[50,20,203]	5	hSpCas9	negative selection	5306229
39190479	39190501	2	+	27760321	HT29	viability after 10 days	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.18493336217207917	[478,373]	[800,678,343]	2	hSpCas9	negative selection	5306230
39225907	39225929	2	-	27760321	HT29	viability after 10 days	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.45581986768945515	[87,68]	[144,61,192]	6	hSpCas9	negative selection	5306231
39225924	39225946	2	-	27760321	HT29	viability after 10 days	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.7278489396153419	[401,313]	[273,374,165]	-7	hSpCas9	negative selection	5306232
39229364	39229386	2	-	27760321	HT29	viability after 10 days	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-1.2268081827998918	[20,16]	[4,22,2]	-8	hSpCas9	negative selection	5306233
39190421	39190443	2	-	27760321	MOLM13	viability	TTGTGGGAGATACTCAGTATGG	CDKL4	ENSG00000205111	0.35670133704646956	[97,64]	[76,41]	2	hSpCas9	negative selection	5389692
39190479	39190501	2	+	27760321	MOLM13	viability	AATCGGTGTAGGCATCTCCTGG	CDKL4	ENSG00000205111	0.6175675122095367	[545,478]	[728,198]	4	hSpCas9	negative selection	5389693
39225907	39225929	2	-	27760321	MOLM13	viability	CGAGGTGTTCAGGAGAAAAAGG	CDKL4	ENSG00000205111	0.3772189251110707	[104,87]	[151,0]	2	hSpCas9	negative selection	5389694
39225924	39225946	2	-	27760321	MOLM13	viability	AATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	1.8473450813652759	[383,401]	[660,921]	9	hSpCas9	negative selection	5389695
39229364	39229386	2	-	27760321	MOLM13	viability	AGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-1.5230140743722078	[26,20]	[8,0]	-7	hSpCas9	negative selection	5389696
39229056	39229079	2	+	27661255	K562	viability	GTATTTGGAGGGATATCCAGAGG	CDKL4	ENSG00000205111	-0.05080219865269031	[3601,3834]	[3231,2550]	-2	dCas9-KRAB	negative selection	5469965
39229091	39229114	2	+	27661255	K562	viability	GGGGGCGAGCGTAAACACTGGGG	CDKL4	ENSG00000205111	0.18538207162176623	[1082,1217]	[1193,913]	6	dCas9-KRAB	negative selection	5469966
39229484	39229507	2	-	27661255	K562	viability	GACTGGAGAAGGGTCTTATGGGG	CDKL4	ENSG00000205111	0.16555925661730536	[814,847]	[839,662]	6	dCas9-KRAB	negative selection	5469967
39225924	39225947	2	-	27260156	BXPC3	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.017803313781024954	[1025]	[1137,952,1048,1213]	0	hSpCas9	negative selection	5534972
39225912	39225935	2	+	27260156	BXPC3	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.05615422956562788	[814]	[659,968,906,1040]	1	hSpCas9	negative selection	5534973
39229437	39229460	2	+	27260156	BXPC3	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.26328996102078234	[737]	[486,604,733,778]	-5	hSpCas9	negative selection	5534974
39229364	39229387	2	-	27260156	BXPC3	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.05755808782296651	[351]	[333,331,299,461]	-1	hSpCas9	negative selection	5599250
39229424	39229447	2	-	27260156	BXPC3	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.4892042771497554	[266]	[426,346,426,358]	9	hSpCas9	negative selection	5599251
39229453	39229476	2	-	27260156	BXPC3	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.37652452657169433	[193]	[177,297,301,283]	7	hSpCas9	negative selection	5599252
39225924	39225947	2	-	27260156	A673	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.11890995180815644	[1025]	[1466,1284,1513,1082]	3	hSpCas9	negative selection	5656223
39225912	39225935	2	+	27260156	A673	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.2039398283304521	[814]	[1065,1192,1079,1160]	5	hSpCas9	negative selection	5656224
39229437	39229460	2	+	27260156	A673	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.11600437703302358	[737]	[844,715,824,892]	-3	hSpCas9	negative selection	5656225
39229364	39229387	2	-	27260156	A673	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.17886761491276454	[351]	[541,310,267,394]	-4	hSpCas9	negative selection	5720501
39229424	39229447	2	-	27260156	A673	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.4023083975158306	[266]	[459,425,350,463]	8	hSpCas9	negative selection	5720502
39229453	39229476	2	-	27260156	A673	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.06212556249365209	[193]	[321,204,221,232]	1	hSpCas9	negative selection	5720503
39225924	39225947	2	-	27260156	A375	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.20726112763128834	[1025]	[1382,1656,1580,992]	3	hSpCas9	negative selection	5777474
39225912	39225935	2	+	27260156	A375	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.15447441682373098	[814]	[942,917,691,871]	-2	hSpCas9	negative selection	5777475
39229437	39229460	2	+	27260156	A375	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.2273470228964769	[737]	[973,760,526,690]	-3	hSpCas9	negative selection	5777476
39229364	39229387	2	-	27260156	A375	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.10488928003596848	[351]	[324,519,389,530]	1	hSpCas9	negative selection	5841752
39229424	39229447	2	-	27260156	A375	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.3074475918139268	[266]	[440,257,413,408]	4	hSpCas9	negative selection	5841753
39229453	39229476	2	-	27260156	A375	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	-0.12825211079975984	[193]	[256,104,285,170]	-2	hSpCas9	negative selection	5841754
39225924	39225947	2	-	27260156	COLO741	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.054051371791496106	[1025]	[1607,1182,1312]	1	hSpCas9	negative selection	5898725
39225912	39225935	2	+	27260156	COLO741	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.18995075073825995	[814]	[1074,692,976]	-4	hSpCas9	negative selection	5898726
39229437	39229460	2	+	27260156	COLO741	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.08467926651812518	[737]	[1019,905,1067]	1	hSpCas9	negative selection	5898727
39229364	39229387	2	-	27260156	COLO741	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.47196907630348245	[351]	[336,365,273]	-7	hSpCas9	negative selection	5963003
39229424	39229447	2	-	27260156	COLO741	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.4833805541334215	[266]	[537,436,460]	8	hSpCas9	negative selection	5963004
39229453	39229476	2	-	27260156	COLO741	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	-0.07102247213300861	[193]	[320,109,279]	-1	hSpCas9	negative selection	5963005
39225924	39225947	2	-	27260156	CAL120	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.23366388154592332	[1025]	[1262,1133,2059]	3	hSpCas9	negative selection	6019976
39225912	39225935	2	+	27260156	CAL120	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.11874164852263602	[814]	[1454,1117,788]	1	hSpCas9	negative selection	6019977
39229437	39229460	2	+	27260156	CAL120	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.19685122174241748	[737]	[703,731,949]	-3	hSpCas9	negative selection	6019978
39229364	39229387	2	-	27260156	CAL120	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.03775846516021847	[351]	[512,356,422]	0	hSpCas9	negative selection	6084254
39229424	39229447	2	-	27260156	CAL120	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.6972604712362712	[266]	[536,557,520]	8	hSpCas9	negative selection	6084255
39229453	39229476	2	-	27260156	CAL120	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	-0.041364385735125575	[193]	[210,247,240]	0	hSpCas9	negative selection	6084256
39225924	39225947	2	-	27260156	CADOES1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.23148471430958573	[1025]	[1163,1016,1075,1227]	4	hSpCas9	negative selection	6141227
39225912	39225935	2	+	27260156	CADOES1	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.14375476146357125	[814]	[800,505,667,771]	-2	hSpCas9	negative selection	6141228
39229437	39229460	2	+	27260156	CADOES1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.11602359414231589	[737]	[645,518,634,736]	-2	hSpCas9	negative selection	6141229
39229364	39229387	2	-	27260156	CADOES1	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.02298428855361445	[351]	[242,518,216,309]	0	hSpCas9	negative selection	6205505
39229424	39229447	2	-	27260156	CADOES1	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.8866695055254036	[266]	[453,607,337,435]	9	hSpCas9	negative selection	6205506
39229453	39229476	2	-	27260156	CADOES1	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	-0.2747441513163684	[193]	[203,194,87,107]	-5	hSpCas9	negative selection	6205507
39225924	39225947	2	-	27260156	EWS502	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.17229798419019882	[1025]	[1335,1230,1050,1261]	3	hSpCas9	negative selection	6262478
39225912	39225935	2	+	27260156	EWS502	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.061462746176136895	[814]	[737,849,814,918]	-1	hSpCas9	negative selection	6262479
39229437	39229460	2	+	27260156	EWS502	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.045428777372132356	[737]	[821,613,653,1162]	0	hSpCas9	negative selection	6262480
39229364	39229387	2	-	27260156	EWS502	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.026451667425084036	[351]	[486,344,286,385]	0	hSpCas9	negative selection	6326756
39229424	39229447	2	-	27260156	EWS502	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.8347321135386538	[266]	[489,537,573,407]	9	hSpCas9	negative selection	6326757
39229453	39229476	2	-	27260156	EWS502	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.6188999525614157	[193]	[238,301,290,447]	9	hSpCas9	negative selection	6326758
39225924	39225947	2	-	27260156	EW8	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.08448968239600996	[1025]	[756,728,741,909]	-1	hSpCas9	negative selection	6383729
39225912	39225935	2	+	27260156	EW8	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.153140281060952	[814]	[846,567,812,705]	3	hSpCas9	negative selection	6383730
39229437	39229460	2	+	27260156	EW8	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.341625929922275	[737]	[464,460,439,524]	-6	hSpCas9	negative selection	6383731
39229364	39229387	2	-	27260156	EW8	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.062305438632142274	[351]	[273,232,347,323]	1	hSpCas9	negative selection	6448007
39229424	39229447	2	-	27260156	EW8	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.5575872123454788	[266]	[364,324,319,267]	8	hSpCas9	negative selection	6448008
39229453	39229476	2	-	27260156	EW8	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.20764261125397288	[193]	[225,97,169,237]	4	hSpCas9	negative selection	6448009
39225924	39225947	2	-	27260156	CORL105	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.08058945579888732	[1025]	[1386,1111,1438,1175]	1	hSpCas9	negative selection	6504980
39225912	39225935	2	+	27260156	CORL105	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.02029934859237048	[814]	[878,861,1186,872]	0	hSpCas9	negative selection	6504981
39229437	39229460	2	+	27260156	CORL105	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.14684782395375728	[737]	[835,684,931,695]	-3	hSpCas9	negative selection	6504982
39229364	39229387	2	-	27260156	CORL105	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.2717020769744301	[351]	[371,274,375,349]	-5	hSpCas9	negative selection	6569258
39229424	39229447	2	-	27260156	CORL105	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.45489201475956664	[266]	[417,430,514,362]	8	hSpCas9	negative selection	6569259
39229453	39229476	2	-	27260156	CORL105	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.2155124056054103	[193]	[339,215,304,203]	4	hSpCas9	negative selection	6569260
39225924	39225947	2	-	27260156	HS294T	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.20561692776345764	[1025]	[280,305,372,437]	-3	hSpCas9	negative selection	6626231
39225912	39225935	2	+	27260156	HS294T	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.061927149368622314	[814]	[279,378,234,313]	-1	hSpCas9	negative selection	6626232
39229437	39229460	2	+	27260156	HS294T	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.248567352476749	[737]	[190,192,273,321]	-3	hSpCas9	negative selection	6626233
39229364	39229387	2	-	27260156	HS294T	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.9434002329730475	[351]	[123,242,516,158]	9	hSpCas9	negative selection	6690509
39229424	39229447	2	-	27260156	HS294T	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.9095296061304091	[266]	[183,203,241,135]	9	hSpCas9	negative selection	6690510
39229453	39229476	2	-	27260156	HS294T	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.30549936204178185	[193]	[71,137,62,98]	4	hSpCas9	negative selection	6690511
39225924	39225947	2	-	27260156	HCC44	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.21645526608881238	[1025]	[1284,1123,1617,1424]	3	hSpCas9	negative selection	6747482
39225912	39225935	2	+	27260156	HCC44	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.2307276842113497	[814]	[959,1738,892,603]	3	hSpCas9	negative selection	6747483
39229437	39229460	2	+	27260156	HCC44	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.39096841735751797	[737]	[657,480,911,563]	-6	hSpCas9	negative selection	6747484
39229364	39229387	2	-	27260156	HCC44	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.203215505956512	[351]	[308,320,432,332]	-3	hSpCas9	negative selection	6811760
39229424	39229447	2	-	27260156	HCC44	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.3200247986631065	[266]	[390,417,420,280]	5	hSpCas9	negative selection	6811761
39229453	39229476	2	-	27260156	HCC44	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.2959123108529883	[193]	[289,209,263,318]	5	hSpCas9	negative selection	6811762
39225924	39225947	2	-	27260156	G402	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.09859190670990081	[1025]	[2118,1092,780,1455]	1	hSpCas9	negative selection	6868733
39225912	39225935	2	+	27260156	G402	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.0788607298550843	[814]	[1116,692,820,1132]	-1	hSpCas9	negative selection	6868734
39229437	39229460	2	+	27260156	G402	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.32227750812453515	[737]	[846,1126,308,640]	-4	hSpCas9	negative selection	6868735
39229364	39229387	2	-	27260156	G402	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.09992260894666122	[351]	[532,333,396,354]	-1	hSpCas9	negative selection	6933011
39229424	39229447	2	-	27260156	G402	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.3112687284733504	[266]	[397,463,436,322]	4	hSpCas9	negative selection	6933012
39229453	39229476	2	-	27260156	G402	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	-0.15781913489862198	[193]	[172,40,483,137]	-2	hSpCas9	negative selection	6933013
39225924	39225947	2	-	27260156	L33	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.17431145567016637	[1025]	[799,504,914,1152]	4	hSpCas9	negative selection	6989984
39225912	39225935	2	+	27260156	L33	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.11216361464971691	[814]	[747,315,436,800]	-3	hSpCas9	negative selection	6989985
39229437	39229460	2	+	27260156	L33	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.039082429417302667	[737]	[771,212,471,827]	-1	hSpCas9	negative selection	6989986
39229364	39229387	2	-	27260156	L33	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.05295114599080741	[351]	[278,180,248,242]	-1	hSpCas9	negative selection	7054262
39229424	39229447	2	-	27260156	L33	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.4362586925725403	[266]	[352,170,200,354]	8	hSpCas9	negative selection	7054263
39229453	39229476	2	-	27260156	L33	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.37721777963351455	[193]	[297,133,98,223]	7	hSpCas9	negative selection	7054264
39225924	39225947	2	-	27260156	K562	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.05433421320920662	[1025]	[1124,788,630,963]	0	hSpCas9	negative selection	7111235
39225912	39225935	2	+	27260156	K562	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.3171077173034705	[814]	[521,582,751,470]	-4	hSpCas9	negative selection	7111236
39229437	39229460	2	+	27260156	K562	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.518939137415476	[737]	[727,486,337,313]	-6	hSpCas9	negative selection	7111237
39229364	39229387	2	-	27260156	K562	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.14543907166648834	[351]	[208,162,332,621]	1	hSpCas9	negative selection	7175513
39229424	39229447	2	-	27260156	K562	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	-0.06894170121116738	[266]	[301,242,150,214]	-1	hSpCas9	negative selection	7175514
39229453	39229476	2	-	27260156	K562	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.0908404754402874	[193]	[230,73,253,172]	1	hSpCas9	negative selection	7175515
39225924	39225947	2	-	27260156	HT29	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.04781990347183407	[1025]	[1438,1361,1412,988]	0	hSpCas9	negative selection	7232486
39225912	39225935	2	+	27260156	HT29	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.29104129531556255	[814]	[1103,1468,1188,1104]	6	hSpCas9	negative selection	7232487
39229437	39229460	2	+	27260156	HT29	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.13993418568782323	[737]	[894,1425,854,821]	2	hSpCas9	negative selection	7232488
39229364	39229387	2	-	27260156	HT29	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.07969405602511348	[351]	[354,618,445,398]	1	hSpCas9	negative selection	7296764
39229424	39229447	2	-	27260156	HT29	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.3135735197982892	[266]	[457,386,397,373]	6	hSpCas9	negative selection	7296765
39229453	39229476	2	-	27260156	HT29	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.33660923423537836	[193]	[250,446,307,203]	6	hSpCas9	negative selection	7296766
39225924	39225947	2	-	27260156	MHHES1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.03606348837946394	[1025]	[1304,1189,1411,890]	0	hSpCas9	negative selection	7353737
39225912	39225935	2	+	27260156	MHHES1	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.1632524029016752	[814]	[1092,1228,1006,832]	3	hSpCas9	negative selection	7353738
39229437	39229460	2	+	27260156	MHHES1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.11567542574966672	[737]	[1230,714,699,514]	-2	hSpCas9	negative selection	7353739
39229364	39229387	2	-	27260156	MHHES1	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.15131081176962408	[351]	[174,771,440,378]	2	hSpCas9	negative selection	7418015
39229424	39229447	2	-	27260156	MHHES1	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.7361237216777401	[266]	[609,453,814,195]	9	hSpCas9	negative selection	7418016
39229453	39229476	2	-	27260156	MHHES1	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.4125727781263958	[193]	[481,403,172,161]	7	hSpCas9	negative selection	7418017
39225924	39225947	2	-	27260156	MEWO	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.09520462812058761	[1025]	[1033,856,830]	-2	hSpCas9	negative selection	7474988
39225912	39225935	2	+	27260156	MEWO	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.15119091914304017	[814]	[1007,894,667]	3	hSpCas9	negative selection	7474989
39229437	39229460	2	+	27260156	MEWO	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.13445239361579064	[737]	[669,591,632]	-3	hSpCas9	negative selection	7474990
39229364	39229387	2	-	27260156	MEWO	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.21980060370615467	[351]	[290,255,302]	-5	hSpCas9	negative selection	7539266
39229424	39229447	2	-	27260156	MEWO	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.09084266906299188	[266]	[279,211,308]	2	hSpCas9	negative selection	7539267
39229453	39229476	2	-	27260156	MEWO	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	-0.3298011546960744	[193]	[168,135,132]	-6	hSpCas9	negative selection	7539268
39225924	39225947	2	-	27260156	LNCAPCLONEFGC	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.16403550629182972	[1025]	[1295,850,1113,921]	2	hSpCas9	negative selection	7596239
39225912	39225935	2	+	27260156	LNCAPCLONEFGC	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.2770424339454094	[814]	[933,805,848,986]	4	hSpCas9	negative selection	7596240
39229437	39229460	2	+	27260156	LNCAPCLONEFGC	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.004489891555438885	[737]	[561,644,822,661]	0	hSpCas9	negative selection	7596241
39229364	39229387	2	-	27260156	LNCAPCLONEFGC	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.3941184790335299	[351]	[322,355,547,473]	6	hSpCas9	negative selection	7660517
39229424	39229447	2	-	27260156	LNCAPCLONEFGC	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.7910761770994752	[266]	[449,359,505,373]	9	hSpCas9	negative selection	7660518
39229453	39229476	2	-	27260156	LNCAPCLONEFGC	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.1347041577629824	[193]	[168,173,183,244]	2	hSpCas9	negative selection	7660519
39225924	39225947	2	-	27260156	PANC0327	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.3456153391593797	[1025]	[950,457,985,526]	-5	hSpCas9	negative selection	7717490
39225912	39225935	2	+	27260156	PANC0327	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.434740686627438	[814]	[614,443,701,399]	-6	hSpCas9	negative selection	7717491
39229437	39229460	2	+	27260156	PANC0327	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.1913909844733767	[737]	[605,703,452,518]	-3	hSpCas9	negative selection	7717492
39229364	39229387	2	-	27260156	PANC0327	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.17628914340981808	[351]	[416,343,500,157]	2	hSpCas9	negative selection	7781768
39229424	39229447	2	-	27260156	PANC0327	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.24723922541288568	[266]	[467,235,187,254]	3	hSpCas9	negative selection	7781769
39229453	39229476	2	-	27260156	PANC0327	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.5379718395765747	[193]	[384,186,238,208]	7	hSpCas9	negative selection	7781770
39225924	39225947	2	-	27260156	NCIH2009	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.18858408232254065	[1025]	[1467,1493,1905]	2	hSpCas9	negative selection	7838741
39225912	39225935	2	+	27260156	NCIH2009	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.36627971531668907	[814]	[963,802,898]	-5	hSpCas9	negative selection	7838742
39229437	39229460	2	+	27260156	NCIH2009	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.6695712162843245	[737]	[661,667,615]	-7	hSpCas9	negative selection	7838743
39229364	39229387	2	-	27260156	NCIH2009	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.2584136007435606	[351]	[776,649,372]	3	hSpCas9	negative selection	7903019
39229424	39229447	2	-	27260156	NCIH2009	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.7897999847835582	[266]	[639,683,607]	9	hSpCas9	negative selection	7903020
39229453	39229476	2	-	27260156	NCIH2009	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.36732132405851936	[193]	[251,240,537]	5	hSpCas9	negative selection	7903021
39225924	39225947	2	-	27260156	NCIH1373	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.05315144682711592	[1025]	[1390,1013,1458,151]	0	hSpCas9	negative selection	7959992
39225912	39225935	2	+	27260156	NCIH1373	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.4926674839959614	[814]	[632,672,722,144]	-5	hSpCas9	negative selection	7959993
39229437	39229460	2	+	27260156	NCIH1373	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.6559787025845736	[737]	[635,324,503,178]	-6	hSpCas9	negative selection	7959994
39229364	39229387	2	-	27260156	NCIH1373	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.186141367979791	[351]	[702,242,585,81]	1	hSpCas9	negative selection	8024270
39229424	39229447	2	-	27260156	NCIH1373	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	1.3353144974744138	[266]	[626,913,769,173]	9	hSpCas9	negative selection	8024271
39229453	39229476	2	-	27260156	NCIH1373	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.11610281891651786	[193]	[157,142,363,71]	1	hSpCas9	negative selection	8024272
39225924	39225947	2	-	27260156	PATU8902	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.30246812495803566	[1025]	[1183,1599,1906,2387]	3	hSpCas9	negative selection	8081243
39225912	39225935	2	+	27260156	PATU8902	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.42633330907630085	[814]	[1120,1482,1459,2117]	4	hSpCas9	negative selection	8081244
39229437	39229460	2	+	27260156	PATU8902	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.02723014268441315	[737]	[865,1109,1304,806]	0	hSpCas9	negative selection	8081245
39229364	39229387	2	-	27260156	PATU8902	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.6555906940074141	[351]	[463,268,1358,849]	7	hSpCas9	negative selection	8145521
39229424	39229447	2	-	27260156	PATU8902	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.5737135112643239	[266]	[727,842,258,440]	6	hSpCas9	negative selection	8145522
39229453	39229476	2	-	27260156	PATU8902	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.5447138856075755	[193]	[481,283,542,200]	5	hSpCas9	negative selection	8145523
39225924	39225947	2	-	27260156	PANC1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.10494791056229857	[1025]	[619,1004,718,940]	-2	hSpCas9	negative selection	8202494
39225912	39225935	2	+	27260156	PANC1	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.14513193536607893	[814]	[723,1121,745,593]	2	hSpCas9	negative selection	8202495
39229437	39229460	2	+	27260156	PANC1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.4192990315282252	[737]	[544,761,412,260]	-6	hSpCas9	negative selection	8202496
39229364	39229387	2	-	27260156	PANC1	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.10072837065897988	[351]	[333,617,182,230]	1	hSpCas9	negative selection	8266772
39229424	39229447	2	-	27260156	PANC1	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.5001568086353883	[266]	[438,435,232,220]	7	hSpCas9	negative selection	8266773
39229453	39229476	2	-	27260156	PANC1	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.25339859474657755	[193]	[337,244,99,125]	4	hSpCas9	negative selection	8266774
39225924	39225947	2	-	27260156	PANC0813	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.3734175681207277	[1025]	[1790,1504,1700,1282]	6	hSpCas9	negative selection	8323745
39225912	39225935	2	+	27260156	PANC0813	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.05102642427805504	[814]	[1155,1045,876,905]	0	hSpCas9	negative selection	8323746
39229437	39229460	2	+	27260156	PANC0813	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.20330904897790236	[737]	[1088,958,920,1027]	3	hSpCas9	negative selection	8323747
39229364	39229387	2	-	27260156	PANC0813	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.23672936389402766	[351]	[556,473,397,522]	4	hSpCas9	negative selection	8388023
39229424	39229447	2	-	27260156	PANC0813	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.7868404176824011	[266]	[539,613,484,524]	9	hSpCas9	negative selection	8388024
39229453	39229476	2	-	27260156	PANC0813	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.5892058849329369	[193]	[211,415,373,355]	8	hSpCas9	negative selection	8388025
39225924	39225947	2	-	27260156	RDES	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.13016428663594581	[1025]	[964,1077,1647,1587]	2	hSpCas9	negative selection	8444996
39225912	39225935	2	+	27260156	RDES	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.055029466959955475	[814]	[825,946,1090,1050]	0	hSpCas9	negative selection	8444997
39229437	39229460	2	+	27260156	RDES	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.12453663272224691	[737]	[640,703,1013,776]	-2	hSpCas9	negative selection	8444998
39229364	39229387	2	-	27260156	RDES	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.09528650826012747	[351]	[390,443,399,496]	1	hSpCas9	negative selection	8509274
39229424	39229447	2	-	27260156	RDES	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.638782769534301	[266]	[396,625,347,531]	8	hSpCas9	negative selection	8509275
39229453	39229476	2	-	27260156	RDES	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	-0.07719277739139851	[193]	[193,242,157,247]	-1	hSpCas9	negative selection	8509276
39225924	39225947	2	-	27260156	PC3	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.00923758926218321	[1025]	[728,957,1908,825]	0	hSpCas9	negative selection	8566247
39225912	39225935	2	+	27260156	PC3	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.20424979832520984	[814]	[394,848,1179,642]	-4	hSpCas9	negative selection	8566248
39229437	39229460	2	+	27260156	PC3	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.4769202778270316	[737]	[302,342,911,779]	-8	hSpCas9	negative selection	8566249
39229364	39229387	2	-	27260156	PC3	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.19784254958065634	[351]	[211,346,416,295]	-4	hSpCas9	negative selection	8630525
39229424	39229447	2	-	27260156	PC3	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.0794206020021333	[266]	[202,336,289,297]	1	hSpCas9	negative selection	8630526
39229453	39229476	2	-	27260156	PC3	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.19306186853470275	[193]	[181,120,404,244]	4	hSpCas9	negative selection	8630527
39225924	39225947	2	-	27260156	PATU8988T	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.2151279227678089	[1025]	[1008,1478,850,1311]	3	hSpCas9	negative selection	8687498
39225912	39225935	2	+	27260156	PATU8988T	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.3046250097860179	[814]	[955,811,851,1281]	5	hSpCas9	negative selection	8687499
39229437	39229460	2	+	27260156	PATU8988T	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.08014159681053634	[737]	[530,849,706,621]	-1	hSpCas9	negative selection	8687500
39229364	39229387	2	-	27260156	PATU8988T	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.02756453217570254	[351]	[249,194,482,450]	0	hSpCas9	negative selection	8751776
39229424	39229447	2	-	27260156	PATU8988T	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.3487967236213474	[266]	[143,620,196,385]	6	hSpCas9	negative selection	8751777
39229453	39229476	2	-	27260156	PATU8988T	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.24117879854726487	[193]	[192,289,130,284]	4	hSpCas9	negative selection	8751778
39225924	39225947	2	-	27260156	T47D	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.1797904507874013	[1025]	[1327,1293,1257,1547]	4	hSpCas9	negative selection	8808749
39225912	39225935	2	+	27260156	T47D	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.1709597418692257	[814]	[1018,1057,1089,1109]	3	hSpCas9	negative selection	8808750
39229437	39229460	2	+	27260156	T47D	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.05952295144782904	[737]	[733,811,965,784]	-1	hSpCas9	negative selection	8808751
39229364	39229387	2	-	27260156	T47D	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.05405707220416672	[351]	[351,459,418,469]	1	hSpCas9	negative selection	8873027
39229424	39229447	2	-	27260156	T47D	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.4929156167019491	[266]	[438,484,395,426]	8	hSpCas9	negative selection	8873028
39229453	39229476	2	-	27260156	T47D	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.11396005568148415	[193]	[233,231,205,309]	2	hSpCas9	negative selection	8873029
39225924	39225947	2	-	27260156	SU8686	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	-0.02530733427485865	[1025]	[849,989,1116,1065]	0	hSpCas9	negative selection	8930000
39225912	39225935	2	+	27260156	SU8686	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.2012862683328931	[814]	[661,753,1029,1394]	3	hSpCas9	negative selection	8930001
39229437	39229460	2	+	27260156	SU8686	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.20762062490209088	[737]	[665,836,1031,868]	3	hSpCas9	negative selection	8930002
39229364	39229387	2	-	27260156	SU8686	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.37423463694784914	[351]	[258,220,317,288]	-6	hSpCas9	negative selection	8994278
39229424	39229447	2	-	27260156	SU8686	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.668976612762241	[266]	[325,303,445,671]	9	hSpCas9	negative selection	8994279
39229453	39229476	2	-	27260156	SU8686	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.2749624111067972	[193]	[249,182,272,227]	4	hSpCas9	negative selection	8994280
39225924	39225947	2	-	27260156	SKES1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.0730805489695392	[1025]	[984,1305,904,1111]	1	hSpCas9	negative selection	9051251
39225912	39225935	2	+	27260156	SKES1	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.2150254277119814	[814]	[1131,1108,756,828]	4	hSpCas9	negative selection	9051252
39229437	39229460	2	+	27260156	SKES1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.19851542722798593	[737]	[636,722,562,645]	-4	hSpCas9	negative selection	9051253
39229364	39229387	2	-	27260156	SKES1	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	0.019807311862850174	[351]	[345,565,329,218]	0	hSpCas9	negative selection	9115529
39229424	39229447	2	-	27260156	SKES1	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.37851902177517655	[266]	[484,486,208,249]	7	hSpCas9	negative selection	9115530
39229453	39229476	2	-	27260156	SKES1	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.2215938872510228	[193]	[254,147,292,200]	5	hSpCas9	negative selection	9115531
39225924	39225947	2	-	27260156	TOV112D	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.1863952219072147	[1025]	[928,1210,1343,1180]	3	hSpCas9	negative selection	9172502
39225912	39225935	2	+	27260156	TOV112D	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	-0.046302259461866946	[814]	[808,1032,521,855]	-1	hSpCas9	negative selection	9172503
39229437	39229460	2	+	27260156	TOV112D	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.21844724482622258	[737]	[578,854,540,614]	-4	hSpCas9	negative selection	9172504
39229364	39229387	2	-	27260156	TOV112D	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.3727200458842049	[351]	[244,373,277,215]	-6	hSpCas9	negative selection	9236780
39229424	39229447	2	-	27260156	TOV112D	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.013884373051176069	[266]	[312,220,262,273]	0	hSpCas9	negative selection	9236781
39229453	39229476	2	-	27260156	TOV112D	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.17588710599967738	[193]	[236,277,213,165]	3	hSpCas9	negative selection	9236782
39225924	39225947	2	-	27260156	TC71	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.013736035465742535	[1025]	[874,1093,1063,1434]	0	hSpCas9	negative selection	9293753
39225912	39225935	2	+	27260156	TC71	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.20700964255490417	[814]	[1050,951,1082,939]	5	hSpCas9	negative selection	9293754
39229437	39229460	2	+	27260156	TC71	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.30472964876139913	[737]	[623,567,580,800]	-7	hSpCas9	negative selection	9293755
39229364	39229387	2	-	27260156	TC71	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.01657107188053325	[351]	[408,392,357,328]	0	hSpCas9	negative selection	9358031
39229424	39229447	2	-	27260156	TC71	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.23125641519490325	[266]	[251,421,332,338]	6	hSpCas9	negative selection	9358032
39229453	39229476	2	-	27260156	TC71	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.012631402043215445	[193]	[265,232,125,215]	0	hSpCas9	negative selection	9358033
39225924	39225947	2	-	27260156	TC32	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.09521757904123707	[1025]	[965,795,1397,1059]	1	hSpCas9	negative selection	9415004
39225912	39225935	2	+	27260156	TC32	viability	TTCTCCTGAACACCTCGATGAGG	CDKL4	ENSG00000205111	0.13200788043891176	[814]	[555,803,1072,969]	2	hSpCas9	negative selection	9415005
39229437	39229460	2	+	27260156	TC32	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.3558568751838453	[737]	[521,396,701,602]	-6	hSpCas9	negative selection	9415006
39229364	39229387	2	-	27260156	TC32	viability	AAGAGAAATACGTATGTTGAAGG	CDKL4	ENSG00000205111	-0.09809902165177592	[351]	[260,185,522,340]	-2	hSpCas9	negative selection	9479282
39229424	39229447	2	-	27260156	TC32	viability	AGTAGCTGTTAAAAAATTTGTGG	CDKL4	ENSG00000205111	0.7962839017848482	[266]	[354,314,581,553]	9	hSpCas9	negative selection	9479283
39229453	39229476	2	-	27260156	TC32	viability	AAATGCAGAAACAAAACCTCTGG	CDKL4	ENSG00000205111	0.020955474973344268	[193]	[148,132,347,149]	0	hSpCas9	negative selection	9479284
39178697	39178720	2	-	27869803	HPAFII	viability after 27 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.6656112821990041	[639]	[716,380,NaN]	5	hSpCas9	negative selection	9574980
39179265	39179288	2	+	27869803	HPAFII	viability after 27 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.7064019119841458	[251]	[189,237,NaN]	6	hSpCas9	negative selection	9574981
39187626	39187649	2	-	27869803	HPAFII	viability after 27 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-0.02246443814717053	[208]	[33,169,NaN]	0	hSpCas9	negative selection	9574982
39190462	39190485	2	-	27869803	HPAFII	viability after 27 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.14757602046305485	[398]	[89,350,NaN]	1	hSpCas9	negative selection	9574983
39178697	39178720	2	-	27869803	HPAFII	viability after 15 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.4968028338861956	[639]	[1297,766,NaN]	5	hSpCas9	negative selection	9657429
39179265	39179288	2	+	27869803	HPAFII	viability after 15 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.6489608642417621	[251]	[510,370,NaN]	7	hSpCas9	negative selection	9657430
39187626	39187649	2	-	27869803	HPAFII	viability after 15 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	-0.02790128843563855	[208]	[215,222,NaN]	0	hSpCas9	negative selection	9657431
39190462	39190485	2	-	27869803	HPAFII	viability after 15 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.22899999794303944	[398]	[310,399,NaN]	-3	hSpCas9	negative selection	9657432
39178697	39178720	2	-	27869803	ASPC1	viability after 36 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.4502008293553117	[1833]	[1835,618,393]	4	hSpCas9	negative selection	9739878
39179265	39179288	2	+	27869803	ASPC1	viability after 36 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.5910255856234284	[616]	[258,118,529]	6	hSpCas9	negative selection	9739879
39187626	39187649	2	-	27869803	ASPC1	viability after 36 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.8385491067244173	[433]	[312,355,170]	7	hSpCas9	negative selection	9739880
39190462	39190485	2	-	27869803	ASPC1	viability after 36 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.9002406828632118	[770]	[635,683,258]	8	hSpCas9	negative selection	9739881
39178697	39178720	2	-	27869803	PATU8988S	viability after 35 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	-0.46707088753493653	[1511]	[457,422,NaN]	-5	hSpCas9	negative selection	9822327
39179265	39179288	2	+	27869803	PATU8988S	viability after 35 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.7967279062184724	[534]	[508,238,NaN]	8	hSpCas9	negative selection	9822328
39187626	39187649	2	-	27869803	PATU8988S	viability after 35 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.20074281763059837	[551]	[258,251,NaN]	2	hSpCas9	negative selection	9822329
39190462	39190485	2	-	27869803	PATU8988S	viability after 35 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	-0.3341645986362778	[803]	[195,317,NaN]	-4	hSpCas9	negative selection	9822330
39178697	39178720	2	-	27869803	PATU8988S	viability after 31 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	-0.273731752324365	[1511]	[426,589,NaN]	-3	hSpCas9	negative selection	9904776
39179265	39179288	2	+	27869803	PATU8988S	viability after 31 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.5644490567950767	[534]	[285,352,NaN]	6	hSpCas9	negative selection	9904777
39187626	39187649	2	-	27869803	PATU8988S	viability after 31 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.009275461081735908	[551]	[250,183,NaN]	0	hSpCas9	negative selection	9904778
39190462	39190485	2	-	27869803	PATU8988S	viability after 31 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.06803471867529753	[803]	[288,395,NaN]	0	hSpCas9	negative selection	9904779
39178697	39178720	2	-	27869803	HPAFII	viability after 35 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.4361577832845285	[639]	[467,404,NaN]	3	hSpCas9	negative selection	9987225
39179265	39179288	2	+	27869803	HPAFII	viability after 35 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.7326214885018002	[251]	[179,247,NaN]	5	hSpCas9	negative selection	9987226
39187626	39187649	2	-	27869803	HPAFII	viability after 35 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.04850063562562121	[208]	[12,217,NaN]	0	hSpCas9	negative selection	9987227
39190462	39190485	2	-	27869803	HPAFII	viability after 35 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.7817196590636023	[398]	[160,556,NaN]	5	hSpCas9	negative selection	9987228
39178697	39178720	2	-	27869803	HPAFII	viability after 31 days	CCAAGATCTGCCAGGTACAAAGG	CDKL4	ENSG00000205111	0.318452953284144	[639]	[478,413,NaN]	2	hSpCas9	negative selection	10069674
39179265	39179288	2	+	27869803	HPAFII	viability after 31 days	GCTCTCCAGGAGTTGGGAACAGG	CDKL4	ENSG00000205111	0.8041247051114014	[251]	[200,296,NaN]	6	hSpCas9	negative selection	10069675
39187626	39187649	2	-	27869803	HPAFII	viability after 31 days	TATACCTGAGCCAGAAGACATGG	CDKL4	ENSG00000205111	0.16728008596610894	[208]	[35,235,NaN]	1	hSpCas9	negative selection	10069676
39190462	39190485	2	-	27869803	HPAFII	viability after 31 days	CCGATTATGTAGCTACGAGATGG	CDKL4	ENSG00000205111	0.23591910226482626	[398]	[111,428,NaN]	1	hSpCas9	negative selection	10069677
39225924	39225947	2	-	28162770	P31FUJ	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.26639574252846376	[565]	[799]	3	hSpCas9	negative selection	10130850
39184608	39184631	2	-	28162770	P31FUJ	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.2179452354870628	[817]	[1117]	2	hSpCas9	negative selection	10130851
39190335	39190358	2	-	28162770	P31FUJ	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.10254640623530542	[213]	[269]	1	hSpCas9	negative selection	10130852
39184590	39184613	2	-	28162770	P31FUJ	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.7989701416401008	[246]	[504]	8	hSpCas9	negative selection	10130853
39187638	39187661	2	+	28162770	P31FUJ	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.1993088082234065	[251]	[339]	2	hSpCas9	negative selection	10130854
39190468	39190491	2	+	28162770	P31FUJ	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.8991094710912024	[375]	[823]	8	hSpCas9	negative selection	10130855
39190430	39190453	2	+	28162770	P31FUJ	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.7349831707204516	[316]	[619]	8	hSpCas9	negative selection	10130856
39190349	39190372	2	-	28162770	P31FUJ	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.6208634522272635	[253]	[458]	7	hSpCas9	negative selection	10130857
39229437	39229460	2	+	28162770	P31FUJ	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.2807339286863686	[834]	[1191]	3	hSpCas9	negative selection	10130858
39213461	39213484	2	-	28162770	P31FUJ	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	-0.18766004864894237	[408]	[421]	-2	hSpCas9	negative selection	10130859
39225924	39225947	2	-	28162770	TF1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	NaN	[NaN]	[620]	1	hSpCas9	negative selection	10300216
39184608	39184631	2	-	28162770	TF1	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	NaN	[NaN]	[620]	1	hSpCas9	negative selection	10300217
39190335	39190358	2	-	28162770	TF1	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10300218
39184590	39184613	2	-	28162770	TF1	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10300219
39187638	39187661	2	+	28162770	TF1	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10300220
39190468	39190491	2	+	28162770	TF1	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10300221
39190430	39190453	2	+	28162770	TF1	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10300222
39190349	39190372	2	-	28162770	TF1	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	NaN	[NaN]	[314]	1	hSpCas9	negative selection	10300223
39229437	39229460	2	+	28162770	TF1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	NaN	[NaN]	[621]	1	hSpCas9	negative selection	10300224
39213461	39213484	2	-	28162770	TF1	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	NaN	[NaN]	[581]	1	hSpCas9	negative selection	10300225
39225924	39225947	2	-	28162770	SKM1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.6180871733122055	[156]	[425]	6	hSpCas9	negative selection	10469582
39184608	39184631	2	-	28162770	SKM1	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.3006175886419502	[185]	[404]	3	hSpCas9	negative selection	10469583
39190335	39190358	2	-	28162770	SKM1	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	-0.12338241550528205	[60]	[98]	-1	hSpCas9	negative selection	10469584
39184590	39184613	2	-	28162770	SKM1	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	-0.012104581401948256	[80]	[141]	0	hSpCas9	negative selection	10469585
39187638	39187661	2	+	28162770	SKM1	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.38380783911883826	[74]	[172]	4	hSpCas9	negative selection	10469586
39190468	39190491	2	+	28162770	SKM1	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.4966807373617027	[88]	[221]	5	hSpCas9	negative selection	10469587
39190430	39190453	2	+	28162770	SKM1	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.5565099252317243	[69]	[181]	5	hSpCas9	negative selection	10469588
39190349	39190372	2	-	28162770	SKM1	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.6786918858015467	[46]	[132]	6	hSpCas9	negative selection	10469589
39229437	39229460	2	+	28162770	SKM1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.8747748060285017	[181]	[589]	8	hSpCas9	negative selection	10469590
39213461	39213484	2	-	28162770	SKM1	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.45101679638441033	[71]	[173]	4	hSpCas9	negative selection	10469591
39225924	39225947	2	-	28162770	SKM1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.6180871733122055	[156]	[425]	6	hSpCas9	negative selection	10638948
39184608	39184631	2	-	28162770	SKM1	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.3006175886419502	[185]	[404]	3	hSpCas9	negative selection	10638949
39190335	39190358	2	-	28162770	SKM1	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	-0.12338241550528205	[60]	[98]	-1	hSpCas9	negative selection	10638950
39184590	39184613	2	-	28162770	SKM1	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	-0.012104581401948256	[80]	[141]	0	hSpCas9	negative selection	10638951
39187638	39187661	2	+	28162770	SKM1	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.38380783911883826	[74]	[172]	4	hSpCas9	negative selection	10638952
39190468	39190491	2	+	28162770	SKM1	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.4966807373617027	[88]	[221]	5	hSpCas9	negative selection	10638953
39190430	39190453	2	+	28162770	SKM1	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.5565099252317243	[69]	[181]	5	hSpCas9	negative selection	10638954
39190349	39190372	2	-	28162770	SKM1	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.6786918858015467	[46]	[132]	6	hSpCas9	negative selection	10638955
39229437	39229460	2	+	28162770	SKM1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.8747748060285017	[181]	[589]	8	hSpCas9	negative selection	10638956
39213461	39213484	2	-	28162770	SKM1	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.45101679638441033	[71]	[173]	4	hSpCas9	negative selection	10638957
39225924	39225947	2	-	28162770	PL21	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.2073954304921195	[594]	[298]	1	hSpCas9	negative selection	10808314
39184608	39184631	2	-	28162770	PL21	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.33714054459512344	[521]	[286]	3	hSpCas9	negative selection	10808315
39190335	39190358	2	-	28162770	PL21	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	-0.6859924209524012	[206]	[55]	-5	hSpCas9	negative selection	10808316
39184590	39184613	2	-	28162770	PL21	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	-0.237481170156649	[278]	[102]	-2	hSpCas9	negative selection	10808317
39187638	39187661	2	+	28162770	PL21	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.9141440602122152	[227]	[186]	7	hSpCas9	negative selection	10808318
39190468	39190491	2	+	28162770	PL21	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.16787925076672194	[406]	[198]	1	hSpCas9	negative selection	10808319
39190430	39190453	2	+	28162770	PL21	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	1.5657890868060005	[155]	[200]	9	hSpCas9	negative selection	10808320
39190349	39190372	2	-	28162770	PL21	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.6107719346481628	[163]	[108]	5	hSpCas9	negative selection	10808321
39229437	39229460	2	+	28162770	PL21	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.36049407736729266	[688]	[384]	3	hSpCas9	negative selection	10808322
39213461	39213484	2	-	28162770	PL21	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	1.1698933276211996	[240]	[235]	8	hSpCas9	negative selection	10808323
39225924	39225947	2	-	28162770	P31FUJ	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.26639574252846376	[565]	[799]	3	hSpCas9	negative selection	10977680
39184608	39184631	2	-	28162770	P31FUJ	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.2179452354870628	[817]	[1117]	2	hSpCas9	negative selection	10977681
39190335	39190358	2	-	28162770	P31FUJ	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.10254640623530542	[213]	[269]	1	hSpCas9	negative selection	10977682
39184590	39184613	2	-	28162770	P31FUJ	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.7989701416401008	[246]	[504]	8	hSpCas9	negative selection	10977683
39187638	39187661	2	+	28162770	P31FUJ	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.1993088082234065	[251]	[339]	2	hSpCas9	negative selection	10977684
39190468	39190491	2	+	28162770	P31FUJ	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.8991094710912024	[375]	[823]	8	hSpCas9	negative selection	10977685
39190430	39190453	2	+	28162770	P31FUJ	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.7349831707204516	[316]	[619]	8	hSpCas9	negative selection	10977686
39190349	39190372	2	-	28162770	P31FUJ	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.6208634522272635	[253]	[458]	7	hSpCas9	negative selection	10977687
39229437	39229460	2	+	28162770	P31FUJ	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.2807339286863686	[834]	[1191]	3	hSpCas9	negative selection	10977688
39213461	39213484	2	-	28162770	P31FUJ	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	-0.18766004864894237	[408]	[421]	-2	hSpCas9	negative selection	10977689
39225924	39225947	2	-	28162770	OCIAML5	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.6945852602343003	[317]	[928]	6	hSpCas9	negative selection	11147046
39184608	39184631	2	-	28162770	OCIAML5	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.3801736364287982	[437]	[1028]	3	hSpCas9	negative selection	11147047
39190335	39190358	2	-	28162770	OCIAML5	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.034839650290366744	[125]	[232]	0	hSpCas9	negative selection	11147048
39184590	39184613	2	-	28162770	OCIAML5	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.6174187124372232	[155]	[431]	5	hSpCas9	negative selection	11147049
39187638	39187661	2	+	28162770	OCIAML5	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.6634745288996797	[148]	[425]	6	hSpCas9	negative selection	11147050
39190468	39190491	2	+	28162770	OCIAML5	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.9425340787128604	[210]	[731]	7	hSpCas9	negative selection	11147051
39190430	39190453	2	+	28162770	OCIAML5	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.14114426347336395	[212]	[423]	1	hSpCas9	negative selection	11147052
39190349	39190372	2	-	28162770	OCIAML5	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.405169990431684	[186]	[446]	3	hSpCas9	negative selection	11147053
39229437	39229460	2	+	28162770	OCIAML5	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.7777501656414196	[379]	[1175]	6	hSpCas9	negative selection	11147054
39213461	39213484	2	-	28162770	OCIAML5	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.031192795363417902	[237]	[438]	0	hSpCas9	negative selection	11147055
39225924	39225947	2	-	28162770	EOL1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.5330388077879318	[1114]	[849]	5	hSpCas9	negative selection	11316412
39184608	39184631	2	-	28162770	EOL1	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.4867389646330327	[744]	[549]	4	hSpCas9	negative selection	11316413
39190335	39190358	2	-	28162770	EOL1	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.19840920788868405	[353]	[213]	1	hSpCas9	negative selection	11316414
39184590	39184613	2	-	28162770	EOL1	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	-0.30811298521974056	[516]	[219]	-2	hSpCas9	negative selection	11316415
39187638	39187661	2	+	28162770	EOL1	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	-0.1614759722628326	[500]	[235]	-1	hSpCas9	negative selection	11316416
39190468	39190491	2	+	28162770	EOL1	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	-0.25867405248523556	[653]	[287]	-2	hSpCas9	negative selection	11316417
39190430	39190453	2	+	28162770	EOL1	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.4839751801845531	[284]	[209]	4	hSpCas9	negative selection	11316418
39190349	39190372	2	-	28162770	EOL1	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.7154521728475444	[251]	[217]	6	hSpCas9	negative selection	11316419
39229437	39229460	2	+	28162770	EOL1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.09560233688535069	[992]	[558]	0	hSpCas9	negative selection	11316420
39213461	39213484	2	-	28162770	EOL1	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	1.3384952103208376	[330]	[440]	9	hSpCas9	negative selection	11316421
39225924	39225947	2	-	28162770	MOLM13	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.9762306006628227	[927]	[1319]	7	hSpCas9	negative selection	11485778
39184608	39184631	2	-	28162770	MOLM13	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.8250596905123979	[921]	[1180]	6	hSpCas9	negative selection	11485779
39190335	39190358	2	-	28162770	MOLM13	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	1.2389836532494565	[258]	[441]	8	hSpCas9	negative selection	11485780
39184590	39184613	2	-	28162770	MOLM13	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.9279733606003574	[401]	[552]	7	hSpCas9	negative selection	11485781
39187638	39187661	2	+	28162770	MOLM13	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.5118327291321758	[387]	[399]	4	hSpCas9	negative selection	11485782
39190468	39190491	2	+	28162770	MOLM13	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	1.236002672009332	[558]	[951]	8	hSpCas9	negative selection	11485783
39190430	39190453	2	+	28162770	MOLM13	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.34792875750366603	[375]	[345]	2	hSpCas9	negative selection	11485784
39190349	39190372	2	-	28162770	MOLM13	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	1.1496369448006147	[244]	[392]	8	hSpCas9	negative selection	11485785
39229437	39229460	2	+	28162770	MOLM13	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.4061320420185859	[1073]	[585]	-2	hSpCas9	negative selection	11485786
39213461	39213484	2	-	28162770	MOLM13	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.3856316994254999	[414]	[391]	3	hSpCas9	negative selection	11485787
39225924	39225947	2	-	28162770	HEL	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	1.0157822426145733	[670]	[868]	8	hSpCas9	negative selection	11655144
39184608	39184631	2	-	28162770	HEL	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.08752367467325284	[719]	[489]	0	hSpCas9	negative selection	11655145
39190335	39190358	2	-	28162770	HEL	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	1.4409045826033007	[179]	[312]	9	hSpCas9	negative selection	11655146
39184590	39184613	2	-	28162770	HEL	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.4183468330175606	[360]	[308]	3	hSpCas9	negative selection	11655147
39187638	39187661	2	+	28162770	HEL	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.22283557754969707	[395]	[295]	1	hSpCas9	negative selection	11655148
39190468	39190491	2	+	28162770	HEL	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.8461209605502638	[501]	[577]	7	hSpCas9	negative selection	11655149
39190430	39190453	2	+	28162770	HEL	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.40729025783846257	[258]	[219]	3	hSpCas9	negative selection	11655150
39190349	39190372	2	-	28162770	HEL	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.831316540344561	[221]	[252]	7	hSpCas9	negative selection	11655151
39229437	39229460	2	+	28162770	HEL	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	-0.20132556178646333	[805]	[448]	-1	hSpCas9	negative selection	11655152
39213461	39213484	2	-	28162770	HEL	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	-0.03132001060565737	[358]	[224]	0	hSpCas9	negative selection	11655153
39225924	39225947	2	-	28162770	MV411	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.35687715611483384	[570]	[615]	3	hSpCas9	negative selection	11824510
39184608	39184631	2	-	28162770	MV411	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.4571087310178443	[536]	[620]	4	hSpCas9	negative selection	11824511
39190335	39190358	2	-	28162770	MV411	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.03868480598874695	[192]	[166]	0	hSpCas9	negative selection	11824512
39184590	39184613	2	-	28162770	MV411	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.6147146328450113	[237]	[306]	5	hSpCas9	negative selection	11824513
39187638	39187661	2	+	28162770	MV411	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.42714357301767325	[293]	[332]	4	hSpCas9	negative selection	11824514
39190468	39190491	2	+	28162770	MV411	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.009697165112891648	[440]	[373]	0	hSpCas9	negative selection	11824515
39190430	39190453	2	+	28162770	MV411	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	1.08311023895713	[208]	[372]	8	hSpCas9	negative selection	11824516
39190349	39190372	2	-	28162770	MV411	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	1.381637821708072	[158]	[348]	9	hSpCas9	negative selection	11824517
39229437	39229460	2	+	28162770	MV411	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.6497737293865269	[655]	[866]	6	hSpCas9	negative selection	11824518
39213461	39213484	2	-	28162770	MV411	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.298738779488288	[220]	[228]	2	hSpCas9	negative selection	11824519
39225924	39225947	2	-	28162770	MONOMAC1	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.6898347824834077	[357]	[661]	6	hSpCas9	negative selection	11993876
39184608	39184631	2	-	28162770	MONOMAC1	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.18548041053297437	[414]	[540]	1	hSpCas9	negative selection	11993877
39190335	39190358	2	-	28162770	MONOMAC1	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	-0.7320741224490276	[141]	[97]	-6	hSpCas9	negative selection	11993878
39184590	39184613	2	-	28162770	MONOMAC1	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	1.0296429326799923	[143]	[336]	8	hSpCas9	negative selection	11993879
39187638	39187661	2	+	28162770	MONOMAC1	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	1.4898880646070567	[131]	[424]	9	hSpCas9	negative selection	11993880
39190468	39190491	2	+	28162770	MONOMAC1	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	-0.20986088741713727	[225]	[223]	-2	hSpCas9	negative selection	11993881
39190430	39190453	2	+	28162770	MONOMAC1	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	1.380210688533597	[124]	[372]	9	hSpCas9	negative selection	11993882
39190349	39190372	2	-	28162770	MONOMAC1	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	1.4791747160275561	[96]	[309]	9	hSpCas9	negative selection	11993883
39229437	39229460	2	+	28162770	MONOMAC1	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.08450873547177284	[412]	[501]	0	hSpCas9	negative selection	11993884
39213461	39213484	2	-	28162770	MONOMAC1	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.9338106324000679	[157]	[345]	8	hSpCas9	negative selection	11993885
39225924	39225947	2	-	28162770	OCIAML2	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.38650773516925785	[117]	[854]	4	hSpCas9	negative selection	12163242
39184608	39184631	2	-	28162770	OCIAML2	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.6196907819625328	[88]	[757]	6	hSpCas9	negative selection	12163243
39190335	39190358	2	-	28162770	OCIAML2	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	0.7683368206298024	[33]	[320]	7	hSpCas9	negative selection	12163244
39184590	39184613	2	-	28162770	OCIAML2	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.5681894236483669	[54]	[451]	5	hSpCas9	negative selection	12163245
39187638	39187661	2	+	28162770	OCIAML2	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.02122327108751343	[55]	[314]	0	hSpCas9	negative selection	12163246
39190468	39190491	2	+	28162770	OCIAML2	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	0.38132509488147215	[90]	[656]	3	hSpCas9	negative selection	12163247
39190430	39190453	2	+	28162770	OCIAML2	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	0.620868529243335	[41]	[357]	6	hSpCas9	negative selection	12163248
39190349	39190372	2	-	28162770	OCIAML2	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.21669439310867278	[33]	[218]	2	hSpCas9	negative selection	12163249
39229437	39229460	2	+	28162770	OCIAML2	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.30877103524444127	[133]	[919]	3	hSpCas9	negative selection	12163250
39213461	39213484	2	-	28162770	OCIAML2	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.5893522795860713	[52]	[441]	6	hSpCas9	negative selection	12163251
39225924	39225947	2	-	28162770	OCIAML3	viability	AAATCTTGTGAACCTCATCGAGG	CDKL4	ENSG00000205111	0.1785818635727645	[143]	[491]	1	hSpCas9	negative selection	12332608
39184608	39184631	2	-	28162770	OCIAML3	viability	GTTCTCAGATGTTCATCCTGTGG	CDKL4	ENSG00000205111	0.46795235177718886	[187]	[784]	4	hSpCas9	negative selection	12332609
39190335	39190358	2	-	28162770	OCIAML3	viability	GTGGCCTGGAAAATCAGATGTGG	CDKL4	ENSG00000205111	1.226583108890135	[61]	[437]	8	hSpCas9	negative selection	12332610
39184590	39184613	2	-	28162770	OCIAML3	viability	TGTGGCTCTGAACTTCATGAAGG	CDKL4	ENSG00000205111	0.02748073642210691	[90]	[279]	0	hSpCas9	negative selection	12332611
39187638	39187661	2	+	28162770	OCIAML3	viability	GCTCAGGTATACTGATGCCATGG	CDKL4	ENSG00000205111	0.8051634534956597	[79]	[421]	7	hSpCas9	negative selection	12332612
39190468	39190491	2	+	28162770	OCIAML3	viability	CGTAGCTACATAATCGGTGTAGG	CDKL4	ENSG00000205111	1.0921948401601562	[93]	[604]	8	hSpCas9	negative selection	12332613
39190430	39190453	2	+	28162770	OCIAML3	viability	GTATCTCCCACAAGAAGTTCAGG	CDKL4	ENSG00000205111	-0.32930441412975076	[71]	[172]	-3	hSpCas9	negative selection	12332614
39190349	39190372	2	-	28162770	OCIAML3	viability	ACAGGCCAGCCACTGTGGCCTGG	CDKL4	ENSG00000205111	0.37561871063231805	[47]	[187]	3	hSpCas9	negative selection	12332615
39229437	39229460	2	+	28162770	OCIAML3	viability	AACAGCTACTACTTGTCCAGAGG	CDKL4	ENSG00000205111	0.41003919273853895	[177]	[713]	4	hSpCas9	negative selection	12332616
39213461	39213484	2	-	28162770	OCIAML3	viability	TTTTCCCTCAGAGTTGCTGATGG	CDKL4	ENSG00000205111	0.9211037511430215	[66]	[382]	7	hSpCas9	negative selection	12332617