Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6792
• Symbol:CDKL5
• Description:cyclin dependent kinase like 5

DataSource: http://genomecrispr.dkfz.de/#!/results/CDKL5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18587997	18588020	X	+	26472758	Jiyoye	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.33348983337285587	[240]	[228]	2	hSpCas9	negative selection	28961
18603957	18603980	X	+	26472758	Jiyoye	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.35406404504631106	[248]	[239]	2	hSpCas9	negative selection	28962
18604371	18604394	X	+	26472758	Jiyoye	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	1.441122713429211	[20]	[42]	8	hSpCas9	negative selection	28963
18604804	18604827	X	+	26472758	Jiyoye	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.856389996102805	[218]	[298]	6	hSpCas9	negative selection	28964
18609549	18609572	X	+	26472758	Jiyoye	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	-0.3297902126603329	[219]	[131]	-2	hSpCas9	negative selection	28965
18613154	18613177	X	-	26472758	Jiyoye	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.278158323643767	[338]	[309]	2	hSpCas9	negative selection	28966
18625192	18625215	X	+	26472758	Jiyoye	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.9921378822270296	[105]	[158]	6	hSpCas9	negative selection	28967
18628526	18628549	X	+	26472758	Jiyoye	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	0.6872833006986085	[27]	[33]	5	hSpCas9	negative selection	28968
18564473	18564496	X	+	26472758	Jiyoye	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.160297991879772	[514]	[433]	1	hSpCas9	negative selection	28969
18584317	18584340	X	-	26472758	Jiyoye	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	-0.011537775916368537	[130]	[97]	0	hSpCas9	negative selection	28970
18587997	18588020	X	+	26472758	KBM7	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.7295210684238342	[848,523]	[640,420]	7	hSpCas9	negative selection	220079
18603957	18603980	X	+	26472758	KBM7	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	-0.2615182606088058	[956,932]	[343,396]	-3	hSpCas9	negative selection	220080
18604371	18604394	X	+	26472758	KBM7	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.3861834041583043	[223,259]	[205,100]	4	hSpCas9	negative selection	220081
18604804	18604827	X	+	26472758	KBM7	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	1.2569434174610545	[1052,862]	[1281,881]	9	hSpCas9	negative selection	220082
18609549	18609572	X	+	26472758	KBM7	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.7325231727284979	[441,284]	[267,288]	7	hSpCas9	negative selection	220083
18613154	18613177	X	-	26472758	KBM7	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.1818052383916373	[1094,832]	[622,407]	1	hSpCas9	negative selection	220084
18625192	18625215	X	+	26472758	KBM7	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.17984307078854606	[658,663]	[265,432]	1	hSpCas9	negative selection	220085
18628526	18628549	X	+	26472758	KBM7	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	0.43060591472081544	[178,89]	[39,120]	4	hSpCas9	negative selection	220086
18564473	18564496	X	+	26472758	KBM7	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.24475487655257133	[2122,2094]	[1200,1160]	2	hSpCas9	negative selection	220087
18584317	18584340	X	-	26472758	KBM7	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	-0.16939755070713391	[883,832]	[338,377]	-2	hSpCas9	negative selection	220088
18587997	18588020	X	+	26472758	Raji	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.6828857068456893	[305]	[113]	6	hSpCas9	negative selection	411197
18603957	18603980	X	+	26472758	Raji	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	-0.024840756883489412	[490]	[111]	0	hSpCas9	negative selection	411198
18604371	18604394	X	+	26472758	Raji	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.3231122264290365	[61]	[17]	3	hSpCas9	negative selection	411199
18604804	18604827	X	+	26472758	Raji	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.3034112527106476	[425]	[121]	3	hSpCas9	negative selection	411200
18609549	18609572	X	+	26472758	Raji	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.6378982520723793	[179]	[64]	6	hSpCas9	negative selection	411201
18613154	18613177	X	-	26472758	Raji	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.9624048910615178	[386]	[174]	8	hSpCas9	negative selection	411202
18625192	18625215	X	+	26472758	Raji	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	-0.3038920451090452	[382]	[71]	-3	hSpCas9	negative selection	411203
18628526	18628549	X	+	26472758	Raji	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.3374013072992965	[97]	[17]	-3	hSpCas9	negative selection	411204
18564473	18564496	X	+	26472758	Raji	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.38249077350796856	[1070]	[323]	3	hSpCas9	negative selection	411205
18584317	18584340	X	-	26472758	Raji	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.5369571278103237	[394]	[132]	5	hSpCas9	negative selection	411206
18587997	18588020	X	+	26472758	K562	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	-0.03471620545609966	[846]	[697]	0	hSpCas9	negative selection	602315
18603957	18603980	X	+	26472758	K562	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.3276578880338672	[824]	[873]	2	hSpCas9	negative selection	602316
18604371	18604394	X	+	26472758	K562	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.09347682959170722	[150]	[135]	0	hSpCas9	negative selection	602317
18604804	18604827	X	+	26472758	K562	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.9574204189112883	[861]	[1412]	7	hSpCas9	negative selection	602318
18609549	18609572	X	+	26472758	K562	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.36315627424996966	[407]	[442]	3	hSpCas9	negative selection	602319
18613154	18613177	X	-	26472758	K562	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.3375281320579282	[929]	[991]	2	hSpCas9	negative selection	602320
18625192	18625215	X	+	26472758	K562	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.7963856579535116	[456]	[669]	6	hSpCas9	negative selection	602321
18628526	18628549	X	+	26472758	K562	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	1.3318815689167862	[87]	[186]	9	hSpCas9	negative selection	602322
18564473	18564496	X	+	26472758	K562	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	1.0993226254674773	[1666]	[3014]	8	hSpCas9	negative selection	602323
18584317	18584340	X	-	26472758	K562	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.6297645420084854	[809]	[1057]	5	hSpCas9	negative selection	602324
18575433	18575456	X	+	26627737	DLD1	viability	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.721355009952494	[73]	[84,23,111]	9	hSpCas9	negative selection	845262
18584305	18584328	X	+	26627737	DLD1	viability	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.4427864609412886	[479]	[228,138,235]	4	hSpCas9	negative selection	845263
18588131	18588154	X	-	26627737	DLD1	viability	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-0.18667022288691815	[199]	[46,102,21]	-2	hSpCas9	negative selection	845264
18595362	18595385	X	-	26627737	DLD1	viability	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.7730472952950502	[138]	[88,40,88]	7	hSpCas9	negative selection	845265
18598480	18598503	X	-	26627737	DLD1	viability	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.3701187982288956	[317]	[141,68,165]	4	hSpCas9	negative selection	845266
18604634	18604657	X	+	26627737	DLD1	viability	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.6494918541268234	[455]	[138,49,82]	-6	hSpCas9	negative selection	845267
18575433	18575456	X	+	26627737	GBM cells	viability after 5 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.6659367029080718	[56]	[48,47]	8	hSpCas9	negative selection	927577
18584305	18584328	X	+	26627737	GBM cells	viability after 5 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.15267046713146862	[233]	[108,169]	2	hSpCas9	negative selection	927578
18588131	18588154	X	-	26627737	GBM cells	viability after 5 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-0.19811057950917932	[122]	[67,46]	-3	hSpCas9	negative selection	927579
18595362	18595385	X	-	26627737	GBM cells	viability after 5 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.06883887632799773	[175]	[75,121]	1	hSpCas9	negative selection	927580
18598480	18598503	X	-	26627737	GBM cells	viability after 5 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.29533569599718235	[116]	[105,47]	4	hSpCas9	negative selection	927581
18604634	18604657	X	+	26627737	GBM cells	viability after 5 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.16038330879808638	[148]	[71,70]	-2	hSpCas9	negative selection	927582
18575433	18575456	X	+	26627737	GBM cells	viability after 13 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	-0.37780808162746027	[56]	[41,8]	-4	hSpCas9	negative selection	1009892
18584305	18584328	X	+	26627737	GBM cells	viability after 13 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.4924098256538674	[233]	[230,135]	6	hSpCas9	negative selection	1009893
18588131	18588154	X	-	26627737	GBM cells	viability after 13 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-0.10655730718168721	[122]	[104,26]	-1	hSpCas9	negative selection	1009894
18595362	18595385	X	-	26627737	GBM cells	viability after 13 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	-0.00012184228201239655	[175]	[100,90]	0	hSpCas9	negative selection	1009895
18598480	18598503	X	-	26627737	GBM cells	viability after 13 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.3232863956966937	[116]	[106,56]	4	hSpCas9	negative selection	1009896
18604634	18604657	X	+	26627737	GBM cells	viability after 13 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.7940335766284764	[148]	[55,38]	-7	hSpCas9	negative selection	1009897
18575433	18575456	X	+	26627737	GBM cells	viability after 21 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.29358244874173267	[56]	[38,36]	3	hSpCas9	negative selection	1092207
18584305	18584328	X	+	26627737	GBM cells	viability after 21 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.40018086692063737	[233]	[184,151]	4	hSpCas9	negative selection	1092208
18588131	18588154	X	-	26627737	GBM cells	viability after 21 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-1.029592587017407	[122]	[38,26]	-7	hSpCas9	negative selection	1092209
18595362	18595385	X	-	26627737	GBM cells	viability after 21 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.17078281098382325	[175]	[127,88]	1	hSpCas9	negative selection	1092210
18598480	18598503	X	-	26627737	GBM cells	viability after 21 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.17711944717624084	[116]	[74,68]	2	hSpCas9	negative selection	1092211
18604634	18604657	X	+	26627737	GBM cells	viability after 21 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.47571257050711846	[148]	[64,51]	-4	hSpCas9	negative selection	1092212
18575433	18575456	X	+	26627737	RPE1	viability after 9 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	-0.14676978807312424	[256]	[66,79]	-1	hSpCas9	negative selection	1174522
18584305	18584328	X	+	26627737	RPE1	viability after 9 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	-0.31370535918471326	[835]	[186,240]	-2	hSpCas9	negative selection	1174523
18588131	18588154	X	-	26627737	RPE1	viability after 9 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	1.752214527530514	[116]	[132,110]	8	hSpCas9	negative selection	1174524
18595362	18595385	X	-	26627737	RPE1	viability after 9 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.6607570653817394	[373]	[257,514]	8	hSpCas9	negative selection	1174525
18598480	18598503	X	-	26627737	RPE1	viability after 9 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	-0.6662859483306294	[936]	[107,283]	-5	hSpCas9	negative selection	1174526
18604634	18604657	X	+	26627737	RPE1	viability after 9 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.36189965319484874	[694]	[152,442]	2	hSpCas9	negative selection	1174527
18575433	18575456	X	+	26627737	RPE1	viability after 12 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.2675114266345995	[256]	[35,132]	1	hSpCas9	negative selection	1256837
18584305	18584328	X	+	26627737	RPE1	viability after 12 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.02561417599289069	[835]	[283,169]	0	hSpCas9	negative selection	1256838
18588131	18588154	X	-	26627737	RPE1	viability after 12 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	2.090297007691316	[116]	[145,120]	9	hSpCas9	negative selection	1256839
18595362	18595385	X	-	26627737	RPE1	viability after 12 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.7832493937268334	[373]	[272,422]	8	hSpCas9	negative selection	1256840
18598480	18598503	X	-	26627737	RPE1	viability after 12 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	-0.9601000188809039	[936]	[57,204]	-6	hSpCas9	negative selection	1256841
18604634	18604657	X	+	26627737	RPE1	viability after 12 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.39624791707898155	[694]	[168,326]	2	hSpCas9	negative selection	1256842
18575433	18575456	X	+	26627737	RPE1	viability after 15 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	-0.21709947089088666	[256]	[31,91]	-1	hSpCas9	negative selection	1339152
18584305	18584328	X	+	26627737	RPE1	viability after 15 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.05368972609337082	[835]	[219,269]	0	hSpCas9	negative selection	1339153
18588131	18588154	X	-	26627737	RPE1	viability after 15 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	2.0905882291560856	[116]	[170,111]	8	hSpCas9	negative selection	1339154
18595362	18595385	X	-	26627737	RPE1	viability after 15 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.754918080130539	[373]	[324,387]	8	hSpCas9	negative selection	1339155
18598480	18598503	X	-	26627737	RPE1	viability after 15 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	-0.9239541346535747	[936]	[43,231]	-5	hSpCas9	negative selection	1339156
18604634	18604657	X	+	26627737	RPE1	viability after 15 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.4634381970403463	[694]	[322,220]	3	hSpCas9	negative selection	1339157
18575433	18575456	X	+	26627737	RPE1	viability after 18 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	-0.37967459872778564	[256]	[3,105]	-2	hSpCas9	negative selection	1421467
18584305	18584328	X	+	26627737	RPE1	viability after 18 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.09522683499681907	[835]	[211,271]	0	hSpCas9	negative selection	1421468
18588131	18588154	X	-	26627737	RPE1	viability after 18 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	2.412231317851417	[116]	[140,196]	9	hSpCas9	negative selection	1421469
18595362	18595385	X	-	26627737	RPE1	viability after 18 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.5493599952174615	[373]	[219,375]	7	hSpCas9	negative selection	1421470
18598480	18598503	X	-	26627737	RPE1	viability after 18 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	-0.4879927677925243	[936]	[86,279]	-3	hSpCas9	negative selection	1421471
18604634	18604657	X	+	26627737	RPE1	viability after 18 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.12584234751843448	[694]	[179,230]	0	hSpCas9	negative selection	1421472
18575433	18575456	X	+	26627737	HeLa	viability after 8 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	2.0105682836725967	[46]	[217,34,27]	9	hSpCas9	negative selection	1503782
18584305	18584328	X	+	26627737	HeLa	viability after 8 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.43927983732331377	[405]	[448,257,69]	4	hSpCas9	negative selection	1503783
18588131	18588154	X	-	26627737	HeLa	viability after 8 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	1.305711054381195	[98]	[52,122,129]	8	hSpCas9	negative selection	1503784
18595362	18595385	X	-	26627737	HeLa	viability after 8 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.6252981986863897	[166]	[123,133,82]	5	hSpCas9	negative selection	1503785
18598480	18598503	X	-	26627737	HeLa	viability after 8 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	-0.11117053231135743	[177]	[104,38,77]	-1	hSpCas9	negative selection	1503786
18604634	18604657	X	+	26627737	HeLa	viability after 8 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.042527966364302006	[212]	[102,22,142]	0	hSpCas9	negative selection	1503787
18575433	18575456	X	+	26627737	HeLa	viability after 12 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	2.3672175717156323	[46]	[69,97,131]	9	hSpCas9	negative selection	1586097
18584305	18584328	X	+	26627737	HeLa	viability after 12 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.40386195765346344	[405]	[389,229,49]	3	hSpCas9	negative selection	1586098
18588131	18588154	X	-	26627737	HeLa	viability after 12 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	0.14575378603911826	[98]	[13,62,55]	1	hSpCas9	negative selection	1586099
18595362	18595385	X	-	26627737	HeLa	viability after 12 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.38914022881522636	[166]	[122,62,88]	3	hSpCas9	negative selection	1586100
18598480	18598503	X	-	26627737	HeLa	viability after 12 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.006517048020439287	[177]	[27,29,166]	0	hSpCas9	negative selection	1586101
18604634	18604657	X	+	26627737	HeLa	viability after 12 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.002888702979623403	[212]	[113,100,48]	0	hSpCas9	negative selection	1586102
18575433	18575456	X	+	26627737	HeLa	viability after 15 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.5654121334383488	[46]	[122,25,16]	8	hSpCas9	negative selection	1668412
18584305	18584328	X	+	26627737	HeLa	viability after 15 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.011259348171920196	[405]	[165,151,182]	0	hSpCas9	negative selection	1668413
18588131	18588154	X	-	26627737	HeLa	viability after 15 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	0.9115041272767526	[98]	[129,65,26]	7	hSpCas9	negative selection	1668414
18595362	18595385	X	-	26627737	HeLa	viability after 15 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.1750836917511709	[166]	[68,64,97]	1	hSpCas9	negative selection	1668415
18598480	18598503	X	-	26627737	HeLa	viability after 15 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.01315066220422545	[177]	[30,126,60]	0	hSpCas9	negative selection	1668416
18604634	18604657	X	+	26627737	HeLa	viability after 15 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.1695558231430605	[212]	[71,73,150]	1	hSpCas9	negative selection	1668417
18575433	18575456	X	+	26627737	HeLa	viability after 18 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.6889513445250088	[46]	[91,21,16]	9	hSpCas9	negative selection	1750727
18584305	18584328	X	+	26627737	HeLa	viability after 18 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.09738106550784292	[405]	[127,129,182]	0	hSpCas9	negative selection	1750728
18588131	18588154	X	-	26627737	HeLa	viability after 18 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	0.9159433512285922	[98]	[88,52,26]	7	hSpCas9	negative selection	1750729
18595362	18595385	X	-	26627737	HeLa	viability after 18 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.14230478155412807	[166]	[41,54,97]	1	hSpCas9	negative selection	1750730
18598480	18598503	X	-	26627737	HeLa	viability after 18 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.013886923204566859	[177]	[20,104,60]	0	hSpCas9	negative selection	1750731
18604634	18604657	X	+	26627737	HeLa	viability after 18 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.204649760382157	[212]	[53,59,150]	1	hSpCas9	negative selection	1750732
18575433	18575456	X	+	26627737	HCT116	viability after 6 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	-1.0127861549558437	[163]	[15,10]	-5	hSpCas9	negative selection	1833042
18584305	18584328	X	+	26627737	HCT116	viability after 6 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.6165395773891758	[678]	[211,136]	3	hSpCas9	negative selection	1833043
18588131	18588154	X	-	26627737	HCT116	viability after 6 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-1.2431577997401053	[465]	[77,4]	-6	hSpCas9	negative selection	1833044
18595362	18595385	X	-	26627737	HCT116	viability after 6 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.052214967040976	[266]	[97,80]	6	hSpCas9	negative selection	1833045
18598480	18598503	X	-	26627737	HCT116	viability after 6 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	-1.4456238815698654	[510]	[4,42]	-7	hSpCas9	negative selection	1833046
18604634	18604657	X	+	26627737	HCT116	viability after 6 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.8815198337157821	[648]	[118,225]	5	hSpCas9	negative selection	1833047
18575433	18575456	X	+	26627737	HCT116	viability after 8 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.927604896737577	[41]	[45,33,51]	8	hSpCas9	negative selection	1915357
18584305	18584328	X	+	26627737	HCT116	viability after 8 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	-0.12822810135626345	[434]	[251,226,179]	-1	hSpCas9	negative selection	1915358
18588131	18588154	X	-	26627737	HCT116	viability after 8 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	0.2899307772398265	[118]	[75,48,114]	3	hSpCas9	negative selection	1915359
18595362	18595385	X	-	26627737	HCT116	viability after 8 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.7181139779280028	[54]	[93,102,101]	9	hSpCas9	negative selection	1915360
18598480	18598503	X	-	26627737	HCT116	viability after 8 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	1.227958532901769	[121]	[134,179,156]	8	hSpCas9	negative selection	1915361
18604634	18604657	X	+	26627737	HCT116	viability after 8 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.32712147787958146	[145]	[94,38,58]	-4	hSpCas9	negative selection	1915362
18575433	18575456	X	+	26627737	HCT116	viability after 9 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.4002554903623237	[163]	[47,168]	8	hSpCas9	negative selection	1997672
18584305	18584328	X	+	26627737	HCT116	viability after 9 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	-0.14893240633047042	[678]	[86,223]	-1	hSpCas9	negative selection	1997673
18588131	18588154	X	-	26627737	HCT116	viability after 9 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-0.27320064210940853	[465]	[88,113]	-2	hSpCas9	negative selection	1997674
18595362	18595385	X	-	26627737	HCT116	viability after 9 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	-0.7683485478753835	[266]	[47,36]	-5	hSpCas9	negative selection	1997675
18598480	18598503	X	-	26627737	HCT116	viability after 9 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.1231356215180344	[510]	[304,24]	0	hSpCas9	negative selection	1997676
18604634	18604657	X	+	26627737	HCT116	viability after 9 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.07454862467004247	[648]	[244,100]	0	hSpCas9	negative selection	1997677
18575433	18575456	X	+	26627737	HCT116	viability after 12 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.5251385397202895	[41]	[50,6,34]	5	hSpCas9	negative selection	2079987
18584305	18584328	X	+	26627737	HCT116	viability after 12 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.0945059885311873	[434]	[224,164,341]	1	hSpCas9	negative selection	2079988
18588131	18588154	X	-	26627737	HCT116	viability after 12 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-0.13601353386078907	[118]	[44,65,60]	-1	hSpCas9	negative selection	2079989
18595362	18595385	X	-	26627737	HCT116	viability after 12 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.308325705502892	[54]	[58,118,38]	8	hSpCas9	negative selection	2079990
18598480	18598503	X	-	26627737	HCT116	viability after 12 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.6222208810809923	[121]	[31,101,167]	6	hSpCas9	negative selection	2079991
18604634	18604657	X	+	26627737	HCT116	viability after 12 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.23430682951840198	[145]	[105,32,128]	2	hSpCas9	negative selection	2079992
18575433	18575456	X	+	26627737	HCT116	viability after 15 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.7603819885985423	[41]	[14,27,75]	6	hSpCas9	negative selection	2162302
18584305	18584328	X	+	26627737	HCT116	viability after 15 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.38478516568303456	[434]	[203,211,544]	4	hSpCas9	negative selection	2162303
18588131	18588154	X	-	26627737	HCT116	viability after 15 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	0.001336331672226132	[118]	[60,48,93]	0	hSpCas9	negative selection	2162304
18595362	18595385	X	-	26627737	HCT116	viability after 15 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.3322025956295285	[54]	[59,78,96]	8	hSpCas9	negative selection	2162305
18598480	18598503	X	-	26627737	HCT116	viability after 15 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.7425487833583275	[121]	[96,116,134]	6	hSpCas9	negative selection	2162306
18604634	18604657	X	+	26627737	HCT116	viability after 15 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.2910880066642526	[145]	[117,34,155]	3	hSpCas9	negative selection	2162307
18575433	18575456	X	+	26627737	HCT116	viability after 18 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.6040356192266925	[41]	[77,47,59]	9	hSpCas9	negative selection	2244617
18584305	18584328	X	+	26627737	HCT116	viability after 18 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.3023366903844422	[434]	[96,128,574]	2	hSpCas9	negative selection	2244618
18588131	18588154	X	-	26627737	HCT116	viability after 18 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-0.29691925902315286	[118]	[18,70,48]	-3	hSpCas9	negative selection	2244619
18595362	18595385	X	-	26627737	HCT116	viability after 18 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.4330307029068603	[54]	[30,108,72]	8	hSpCas9	negative selection	2244620
18598480	18598503	X	-	26627737	HCT116	viability after 18 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.9039227964632901	[121]	[83,61,191]	7	hSpCas9	negative selection	2244621
18604634	18604657	X	+	26627737	HCT116	viability after 18 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.7537409185511028	[145]	[220,68,67]	6	hSpCas9	negative selection	2244622
18507094	18507117	X	+	24336569	HL60	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.07501643612900841	[562]	[1254]	0	hSpCas9	negative selection	2256819
18507106	18507129	X	-	24336569	HL60	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	-0.911129184411589	[390]	[439]	-7	hSpCas9	negative selection	2256820
18507124	18507147	X	+	24336569	HL60	viability	ATGAATAAATTTGAGATCCTTGG	CDKL5	ENSG00000008086	0.0363723896649617	[140]	[305]	0	hSpCas9	negative selection	2256821
18510823	18510846	X	-	24336569	HL60	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.3993013491714824	[774]	[2162]	3	hSpCas9	negative selection	2256822
18510833	18510856	X	+	24336569	HL60	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.28773781111756946	[1458]	[3768]	2	hSpCas9	negative selection	2256823
18564473	18564496	X	+	24336569	HL60	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.14134546543819804	[987]	[2305]	1	hSpCas9	negative selection	2256824
18564491	18564514	X	+	24336569	HL60	viability	TGTGGCGATCAAGAAATTCAAGG	CDKL5	ENSG00000008086	0.20768136427719996	[907]	[2218]	2	hSpCas9	negative selection	2256825
18564501	18564524	X	+	24336569	HL60	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.5939136953144784	[1071]	[3423]	5	hSpCas9	negative selection	2256826
18575394	18575417	X	+	24336569	HL60	viability	AATGCTTCGGACTCTCAAGCAGG	CDKL5	ENSG00000008086	0.28963005106235057	[524]	[1357]	2	hSpCas9	negative selection	2256827
18575429	18575452	X	+	24336569	HL60	viability	AGTTGAAGGAAGCATTTCGTCGG	CDKL5	ENSG00000008086	-0.06031165988110976	[1150]	[2335]	0	hSpCas9	negative selection	2256828
18507094	18507117	X	+	24336569	KBM7	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.6166363637223149	[367]	[1538]	5	hSpCas9	negative selection	2323996
18507106	18507129	X	-	24336569	KBM7	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.44169398558458656	[378]	[1403]	4	hSpCas9	negative selection	2323997
18507124	18507147	X	+	24336569	KBM7	viability	ATGAATAAATTTGAGATCCTTGG	CDKL5	ENSG00000008086	-0.9242712137415159	[246]	[354]	-6	hSpCas9	negative selection	2323998
18510823	18510846	X	-	24336569	KBM7	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	1.189654051032107	[392]	[2444]	8	hSpCas9	negative selection	2323999
18510833	18510856	X	+	24336569	KBM7	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.8264299557560277	[1003]	[4855]	7	hSpCas9	negative selection	2324000
18564473	18564496	X	+	24336569	KBM7	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.6327804200974435	[514]	[2177]	6	hSpCas9	negative selection	2324001
18564491	18564514	X	+	24336569	KBM7	viability	TGTGGCGATCAAGAAATTCAAGG	CDKL5	ENSG00000008086	1.0507454680091073	[345]	[1954]	8	hSpCas9	negative selection	2324002
18564501	18564524	X	+	24336569	KBM7	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.38210709257875886	[1043]	[3710]	3	hSpCas9	negative selection	2324003
18575394	18575417	X	+	24336569	KBM7	viability	AATGCTTCGGACTCTCAAGCAGG	CDKL5	ENSG00000008086	0.027459692604657637	[676]	[1881]	0	hSpCas9	negative selection	2324004
18575429	18575452	X	+	24336569	KBM7	viability	AGTTGAAGGAAGCATTTCGTCGG	CDKL5	ENSG00000008086	0.5019943220346919	[967]	[3738]	4	hSpCas9	negative selection	2324005
18442066	18442089	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGCCTTCACTGTGACAGAAAGG	CDKL5	ENSG00000008086	1.6731122921121888	[776,106]	[463,136]	6	dCas9-VP64	positive selection	2391474
18442094	18442117	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCTCCCCTATCTCCACTCAGG	CDKL5	ENSG00000008086	-0.4519019400379476	[459,270]	[97,14]	-2	dCas9-VP64	positive selection	2391475
18442123	18442146	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTAGTGTCCAGCCTCTCAGG	CDKL5	ENSG00000008086	-1.0090677703258166	[67,61]	[8,3]	-6	dCas9-VP64	positive selection	2391476
18471399	18471422	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCTTGTTCTGTTGCCCAGGCGG	CDKL5	ENSG00000008086	-0.7436358345773786	[112,706]	[22,87]	-4	dCas9-VP64	positive selection	2407570
18449965	18449988	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTATTTTTAGTAGAGTCGGGG	CDKL5	ENSG00000008086	1.0128281800924883	[250,40]	[67,58]	4	dCas9-VP64	positive selection	2417012
18475204	18475227	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCCAAGGTGG	CDKL5	ENSG00000008086	0.21234444010885142	[57,122]	[21,23]	1	dCas9-VP64	positive selection	2422545
18611389	18611412	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACCCCAGCCTAG	CDKL5	ENSG00000008086	0.36632392651586576	[208,84]	[58,21]	1	dCas9-VP64	positive selection	2442343
18445119	18445142	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGCCATTGCACTCCAGCCTAG	CDKL5	ENSG00000008086	-0.5971814264096912	[233,130]	[36,14]	-3	dCas9-VP64	positive selection	2446968
18438139	18438162	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTCCCGAG	CDKL5	ENSG00000008086	0.6259309833286419	[228,309]	[35,151]	2	dCas9-VP64	positive selection	2450480
18528861	18528884	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGATCACTTGAGGCCCAG	CDKL5	ENSG00000008086	3.7396651611807004	[3,72]	[11,226]	9	dCas9-VP64	positive selection	2451772
18471400	18471423	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGTTCTGTTGCCCAGGCGGG	CDKL5	ENSG00000008086	-0.6863317618464422	[59,137]	[14,10]	-3	dCas9-VP64	positive selection	2464094
18442066	18442089	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGCCTTCACTGTGACAGAAAGG	CDKL5	ENSG00000008086	0.5382556778689539	[185,220]	[128,65]	4	dCas9-VP64	positive selection	2486729
18442094	18442117	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCTCCCCTATCTCCACTCAGG	CDKL5	ENSG00000008086	-0.2823630229575005	[263,133]	[68,38]	-3	dCas9-VP64	positive selection	2486730
18442123	18442146	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTAGTGTCCAGCCTCTCAGG	CDKL5	ENSG00000008086	-0.054977081068285916	[158,243]	[36,86]	0	dCas9-VP64	positive selection	2486731
18471399	18471422	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCTTGTTCTGTTGCCCAGGCGG	CDKL5	ENSG00000008086	1.9662405034468662	[80,153]	[37,252]	8	dCas9-VP64	positive selection	2502825
18449965	18449988	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTATTTTTAGTAGAGTCGGGG	CDKL5	ENSG00000008086	-0.03815698815020019	[56,33]	[21,6]	0	dCas9-VP64	positive selection	2512267
18475204	18475227	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCCAAGGTGG	CDKL5	ENSG00000008086	-0.9329704115466368	[100,219]	[26,25]	-8	dCas9-VP64	positive selection	2517800
18611389	18611412	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACCCCAGCCTAG	CDKL5	ENSG00000008086	-0.6605575882505516	[226,108]	[36,31]	-6	dCas9-VP64	positive selection	2537598
18445119	18445142	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGCCATTGCACTCCAGCCTAG	CDKL5	ENSG00000008086	0.14726127288975888	[140,101]	[59,28]	1	dCas9-VP64	positive selection	2542223
18438139	18438162	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTCCCGAG	CDKL5	ENSG00000008086	0.8832307312434098	[227,267]	[69,222]	6	dCas9-VP64	positive selection	2545735
18528861	18528884	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGATCACTTGAGGCCCAG	CDKL5	ENSG00000008086	0.5989374680558959	[87,40]	[52,11]	4	dCas9-VP64	positive selection	2547027
18471400	18471423	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGTTCTGTTGCCCAGGCGGG	CDKL5	ENSG00000008086	-0.6931781766025115	[37,108]	[16,10]	-6	dCas9-VP64	positive selection	2559349
18587966	18587989	X	+	27260157	DLD1	viability	AAAGTCCGTGGACATGTGGTCGG	CDKL5	ENSG00000008086	0.485383204757091	[]	[]	8	hSpCas9	negative selection	2574058
18507094	18507117	X	+	27260157	DLD1	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	1.10102885532716	[]	[]	9	hSpCas9	negative selection	2575080
18598532	18598555	X	-	27260157	DLD1	viability	AGAACGATCCAGAAGTCTCTGGG	CDKL5	ENSG00000008086	0.517984098336193	[]	[]	8	hSpCas9	negative selection	2580721
18587982	18588005	X	+	27260157	DLD1	viability	TGGTCGGTGGGCTGTATTCTTGG	CDKL5	ENSG00000008086	-0.13665521901643	[]	[]	-1	hSpCas9	negative selection	2581097
18564491	18564514	X	+	27260157	DLD1	viability	TGTGGCGATCAAGAAATTCAAGG	CDKL5	ENSG00000008086	0.53342068703449	[]	[]	8	hSpCas9	negative selection	2581170
18507124	18507147	X	+	27260157	DLD1	viability	ATGAATAAATTTGAGATCCTTGG	CDKL5	ENSG00000008086	0.522520489877	[]	[]	8	hSpCas9	negative selection	2584949
18564473	18564496	X	+	27260157	DLD1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.0954158611317673	[]	[]	3	hSpCas9	negative selection	2586224
18575429	18575452	X	+	27260157	DLD1	viability	AGTTGAAGGAAGCATTTCGTCGG	CDKL5	ENSG00000008086	-0.117198638494621	[]	[]	-1	hSpCas9	negative selection	2611315
18564501	18564524	X	+	27260157	DLD1	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.459035245268514	[]	[]	7	hSpCas9	negative selection	2611791
18603957	18603980	X	+	27260157	DLD1	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.499847781588012	[]	[]	8	hSpCas9	negative selection	2614857
18510833	18510856	X	+	27260157	DLD1	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.230275009928442	[]	[]	3	hSpCas9	negative selection	2615973
18575432	18575455	X	+	27260157	DLD1	viability	TGAAGGAAGCATTTCGTCGGAGG	CDKL5	ENSG00000008086	1.00376423648293	[]	[]	9	hSpCas9	negative selection	2616127
18510823	18510846	X	-	27260157	DLD1	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.303263843770974	[]	[]	4	hSpCas9	negative selection	2620377
18588123	18588146	X	-	27260157	DLD1	viability	ACCCGGAGCCCATGGAAGCGAGG	CDKL5	ENSG00000008086	1.02711483450661	[]	[]	9	hSpCas9	negative selection	2621861
18584305	18584328	X	+	27260157	DLD1	viability	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.422894396725449	[]	[]	7	hSpCas9	negative selection	2622021
18507106	18507129	X	-	27260157	DLD1	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.164362700497132	[]	[]	3	hSpCas9	negative selection	2644399
18598541	18598564	X	+	27260157	DLD1	viability	TTCTGGATCGTTCTCCTTCAAGG	CDKL5	ENSG00000008086	0.357743908898621	[]	[]	4	hSpCas9	negative selection	2644547
18587954	18587977	X	+	27260157	DLD1	viability	CGCTCCCTATGGAAAGTCCGTGG	CDKL5	ENSG00000008086	0.297404916569851	[]	[]	4	hSpCas9	negative selection	2645334
18575394	18575417	X	+	27260157	DLD1	viability	AATGCTTCGGACTCTCAAGCAGG	CDKL5	ENSG00000008086	0.869570643892798	[]	[]	9	hSpCas9	negative selection	2645807
18603967	18603990	X	+	27260157	DLD1	viability	ACCTGAGTGTAGGCCTGCCCCGG	CDKL5	ENSG00000008086	0.508106384435533	[]	[]	8	hSpCas9	negative selection	2647369
18587966	18587989	X	+	27260157	HT1080	viability	AAAGTCCGTGGACATGTGGTCGG	CDKL5	ENSG00000008086	0.603279091464094	[]	[]	5	hSpCas9	negative selection	2650188
18507094	18507117	X	+	27260157	HT1080	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	1.22510230853312	[]	[]	8	hSpCas9	negative selection	2651210
18598532	18598555	X	-	27260157	HT1080	viability	AGAACGATCCAGAAGTCTCTGGG	CDKL5	ENSG00000008086	0.580965244834242	[]	[]	5	hSpCas9	negative selection	2656851
18587982	18588005	X	+	27260157	HT1080	viability	TGGTCGGTGGGCTGTATTCTTGG	CDKL5	ENSG00000008086	-0.0975546941093378	[]	[]	0	hSpCas9	negative selection	2657227
18564491	18564514	X	+	27260157	HT1080	viability	TGTGGCGATCAAGAAATTCAAGG	CDKL5	ENSG00000008086	-0.547959342789373	[]	[]	-7	hSpCas9	negative selection	2657300
18507124	18507147	X	+	27260157	HT1080	viability	ATGAATAAATTTGAGATCCTTGG	CDKL5	ENSG00000008086	1.23826435319061	[]	[]	8	hSpCas9	negative selection	2661079
18564473	18564496	X	+	27260157	HT1080	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.104098492265391	[]	[]	1	hSpCas9	negative selection	2662354
18575429	18575452	X	+	27260157	HT1080	viability	AGTTGAAGGAAGCATTTCGTCGG	CDKL5	ENSG00000008086	-0.00920367535104787	[]	[]	0	hSpCas9	negative selection	2687445
18564501	18564524	X	+	27260157	HT1080	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.719330287042199	[]	[]	6	hSpCas9	negative selection	2687921
18603957	18603980	X	+	27260157	HT1080	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.691589404815599	[]	[]	6	hSpCas9	negative selection	2690987
18510833	18510856	X	+	27260157	HT1080	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.196692235078682	[]	[]	1	hSpCas9	negative selection	2692103
18575432	18575455	X	+	27260157	HT1080	viability	TGAAGGAAGCATTTCGTCGGAGG	CDKL5	ENSG00000008086	0.569486037653251	[]	[]	5	hSpCas9	negative selection	2692257
18510823	18510846	X	-	27260157	HT1080	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.604120567527794	[]	[]	5	hSpCas9	negative selection	2696507
18588123	18588146	X	-	27260157	HT1080	viability	ACCCGGAGCCCATGGAAGCGAGG	CDKL5	ENSG00000008086	0.838473177071299	[]	[]	7	hSpCas9	negative selection	2697991
18584305	18584328	X	+	27260157	HT1080	viability	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.86631434363237	[]	[]	7	hSpCas9	negative selection	2698151
18507106	18507129	X	-	27260157	HT1080	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.858959613983636	[]	[]	7	hSpCas9	negative selection	2720529
18598541	18598564	X	+	27260157	HT1080	viability	TTCTGGATCGTTCTCCTTCAAGG	CDKL5	ENSG00000008086	1.11883739061374	[]	[]	8	hSpCas9	negative selection	2720677
18587954	18587977	X	+	27260157	HT1080	viability	CGCTCCCTATGGAAAGTCCGTGG	CDKL5	ENSG00000008086	0.295385737969032	[]	[]	2	hSpCas9	negative selection	2721464
18575394	18575417	X	+	27260157	HT1080	viability	AATGCTTCGGACTCTCAAGCAGG	CDKL5	ENSG00000008086	0.941122605150518	[]	[]	7	hSpCas9	negative selection	2721937
18603967	18603990	X	+	27260157	HT1080	viability	ACCTGAGTGTAGGCCTGCCCCGG	CDKL5	ENSG00000008086	-0.00322236395175185	[]	[]	0	hSpCas9	negative selection	2723499
18587966	18587989	X	+	27260157	MKN45	viability	AAAGTCCGTGGACATGTGGTCGG	CDKL5	ENSG00000008086	-0.583042818229423	[]	[]	-6	hSpCas9	negative selection	2726318
18507094	18507117	X	+	27260157	MKN45	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.676939744380482	[]	[]	7	hSpCas9	negative selection	2727340
18598532	18598555	X	-	27260157	MKN45	viability	AGAACGATCCAGAAGTCTCTGGG	CDKL5	ENSG00000008086	-0.0521273649928793	[]	[]	0	hSpCas9	negative selection	2732981
18587982	18588005	X	+	27260157	MKN45	viability	TGGTCGGTGGGCTGTATTCTTGG	CDKL5	ENSG00000008086	0.475572819251619	[]	[]	6	hSpCas9	negative selection	2733357
18564491	18564514	X	+	27260157	MKN45	viability	TGTGGCGATCAAGAAATTCAAGG	CDKL5	ENSG00000008086	-0.156324748086894	[]	[]	0	hSpCas9	negative selection	2733430
18507124	18507147	X	+	27260157	MKN45	viability	ATGAATAAATTTGAGATCCTTGG	CDKL5	ENSG00000008086	0.224328887324894	[]	[]	5	hSpCas9	negative selection	2737209
18564473	18564496	X	+	27260157	MKN45	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.552031046581844	[]	[]	7	hSpCas9	negative selection	2738484
18575429	18575452	X	+	27260157	MKN45	viability	AGTTGAAGGAAGCATTTCGTCGG	CDKL5	ENSG00000008086	0.482636452812452	[]	[]	6	hSpCas9	negative selection	2763575
18564501	18564524	X	+	27260157	MKN45	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	1.02514155662907	[]	[]	8	hSpCas9	negative selection	2764051
18603957	18603980	X	+	27260157	MKN45	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	-0.212925418367703	[]	[]	-1	hSpCas9	negative selection	2767117
18510833	18510856	X	+	27260157	MKN45	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.218660784589213	[]	[]	5	hSpCas9	negative selection	2768233
18575432	18575455	X	+	27260157	MKN45	viability	TGAAGGAAGCATTTCGTCGGAGG	CDKL5	ENSG00000008086	0.498659109395754	[]	[]	6	hSpCas9	negative selection	2768387
18510823	18510846	X	-	27260157	MKN45	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.306997088205064	[]	[]	5	hSpCas9	negative selection	2772637
18588123	18588146	X	-	27260157	MKN45	viability	ACCCGGAGCCCATGGAAGCGAGG	CDKL5	ENSG00000008086	1.18684978108291	[]	[]	9	hSpCas9	negative selection	2774121
18584305	18584328	X	+	27260157	MKN45	viability	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.643012957245264	[]	[]	7	hSpCas9	negative selection	2774281
18507106	18507129	X	-	27260157	MKN45	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.773361973027406	[]	[]	7	hSpCas9	negative selection	2796659
18598541	18598564	X	+	27260157	MKN45	viability	TTCTGGATCGTTCTCCTTCAAGG	CDKL5	ENSG00000008086	-0.0515657368931269	[]	[]	0	hSpCas9	negative selection	2796807
18587954	18587977	X	+	27260157	MKN45	viability	CGCTCCCTATGGAAAGTCCGTGG	CDKL5	ENSG00000008086	0.402920352036249	[]	[]	6	hSpCas9	negative selection	2797594
18575394	18575417	X	+	27260157	MKN45	viability	AATGCTTCGGACTCTCAAGCAGG	CDKL5	ENSG00000008086	0.818794623432577	[]	[]	8	hSpCas9	negative selection	2798067
18603967	18603990	X	+	27260157	MKN45	viability	ACCTGAGTGTAGGCCTGCCCCGG	CDKL5	ENSG00000008086	-0.138964819799987	[]	[]	0	hSpCas9	negative selection	2799629
18587966	18587989	X	+	27260157	RKO	viability	AAAGTCCGTGGACATGTGGTCGG	CDKL5	ENSG00000008086	0.357021130634171	[]	[]	2	hSpCas9	negative selection	2802448
18507094	18507117	X	+	27260157	RKO	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	1.2577428352963	[]	[]	9	hSpCas9	negative selection	2803470
18598532	18598555	X	-	27260157	RKO	viability	AGAACGATCCAGAAGTCTCTGGG	CDKL5	ENSG00000008086	1.43633274495791	[]	[]	9	hSpCas9	negative selection	2809111
18587982	18588005	X	+	27260157	RKO	viability	TGGTCGGTGGGCTGTATTCTTGG	CDKL5	ENSG00000008086	-0.439767363454084	[]	[]	-6	hSpCas9	negative selection	2809487
18564491	18564514	X	+	27260157	RKO	viability	TGTGGCGATCAAGAAATTCAAGG	CDKL5	ENSG00000008086	0.037075319808268	[]	[]	0	hSpCas9	negative selection	2809560
18507124	18507147	X	+	27260157	RKO	viability	ATGAATAAATTTGAGATCCTTGG	CDKL5	ENSG00000008086	1.2048373667046	[]	[]	9	hSpCas9	negative selection	2813339
18564473	18564496	X	+	27260157	RKO	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.0183016758729056	[]	[]	0	hSpCas9	negative selection	2814614
18575429	18575452	X	+	27260157	RKO	viability	AGTTGAAGGAAGCATTTCGTCGG	CDKL5	ENSG00000008086	0.0157443229489514	[]	[]	0	hSpCas9	negative selection	2839705
18564501	18564524	X	+	27260157	RKO	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	1.45798643707136	[]	[]	9	hSpCas9	negative selection	2840181
18603957	18603980	X	+	27260157	RKO	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	1.04666400178118	[]	[]	9	hSpCas9	negative selection	2843247
18510833	18510856	X	+	27260157	RKO	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.519599285854321	[]	[]	2	hSpCas9	negative selection	2844363
18575432	18575455	X	+	27260157	RKO	viability	TGAAGGAAGCATTTCGTCGGAGG	CDKL5	ENSG00000008086	0.232830227490583	[]	[]	1	hSpCas9	negative selection	2844517
18510823	18510846	X	-	27260157	RKO	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.121843728283106	[]	[]	0	hSpCas9	negative selection	2848767
18588123	18588146	X	-	27260157	RKO	viability	ACCCGGAGCCCATGGAAGCGAGG	CDKL5	ENSG00000008086	1.16156936453302	[]	[]	9	hSpCas9	negative selection	2850251
18584305	18584328	X	+	27260157	RKO	viability	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.441740341263917	[]	[]	2	hSpCas9	negative selection	2850411
18507106	18507129	X	-	27260157	RKO	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.569453843370005	[]	[]	3	hSpCas9	negative selection	2872789
18598541	18598564	X	+	27260157	RKO	viability	TTCTGGATCGTTCTCCTTCAAGG	CDKL5	ENSG00000008086	0.764280023466174	[]	[]	8	hSpCas9	negative selection	2872937
18587954	18587977	X	+	27260157	RKO	viability	CGCTCCCTATGGAAAGTCCGTGG	CDKL5	ENSG00000008086	0.220747897106826	[]	[]	1	hSpCas9	negative selection	2873724
18575394	18575417	X	+	27260157	RKO	viability	AATGCTTCGGACTCTCAAGCAGG	CDKL5	ENSG00000008086	0.269764088114058	[]	[]	1	hSpCas9	negative selection	2874197
18603967	18603990	X	+	27260157	RKO	viability	ACCTGAGTGTAGGCCTGCCCCGG	CDKL5	ENSG00000008086	0.890787952446787	[]	[]	8	hSpCas9	negative selection	2875759
18587966	18587989	X	+	27260157	SF268	viability	AAAGTCCGTGGACATGTGGTCGG	CDKL5	ENSG00000008086	-0.0930705725164542	[]	[]	0	hSpCas9	negative selection	2878578
18507094	18507117	X	+	27260157	SF268	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.515713051338455	[]	[]	8	hSpCas9	negative selection	2879600
18598532	18598555	X	-	27260157	SF268	viability	AGAACGATCCAGAAGTCTCTGGG	CDKL5	ENSG00000008086	1.01865564160475	[]	[]	9	hSpCas9	negative selection	2885241
18587982	18588005	X	+	27260157	SF268	viability	TGGTCGGTGGGCTGTATTCTTGG	CDKL5	ENSG00000008086	-0.174511412625727	[]	[]	-1	hSpCas9	negative selection	2885617
18564491	18564514	X	+	27260157	SF268	viability	TGTGGCGATCAAGAAATTCAAGG	CDKL5	ENSG00000008086	0.237488192812052	[]	[]	3	hSpCas9	negative selection	2885690
18507124	18507147	X	+	27260157	SF268	viability	ATGAATAAATTTGAGATCCTTGG	CDKL5	ENSG00000008086	1.05789596588792	[]	[]	9	hSpCas9	negative selection	2889469
18564473	18564496	X	+	27260157	SF268	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.371916017197557	[]	[]	4	hSpCas9	negative selection	2890744
18575429	18575452	X	+	27260157	SF268	viability	AGTTGAAGGAAGCATTTCGTCGG	CDKL5	ENSG00000008086	0.52724029436937	[]	[]	8	hSpCas9	negative selection	2915835
18564501	18564524	X	+	27260157	SF268	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	1.0770665139499	[]	[]	9	hSpCas9	negative selection	2916311
18603957	18603980	X	+	27260157	SF268	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	1.03950533747993	[]	[]	9	hSpCas9	negative selection	2919377
18510833	18510856	X	+	27260157	SF268	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.57599918906717	[]	[]	8	hSpCas9	negative selection	2920493
18575432	18575455	X	+	27260157	SF268	viability	TGAAGGAAGCATTTCGTCGGAGG	CDKL5	ENSG00000008086	0.318885633314765	[]	[]	4	hSpCas9	negative selection	2920647
18510823	18510846	X	-	27260157	SF268	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	1.01512085032506	[]	[]	9	hSpCas9	negative selection	2924897
18588123	18588146	X	-	27260157	SF268	viability	ACCCGGAGCCCATGGAAGCGAGG	CDKL5	ENSG00000008086	1.06438941992262	[]	[]	9	hSpCas9	negative selection	2926381
18584305	18584328	X	+	27260157	SF268	viability	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.0832274351916585	[]	[]	0	hSpCas9	negative selection	2926541
18507106	18507129	X	-	27260157	SF268	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.491420153344659	[]	[]	7	hSpCas9	negative selection	2948919
18598541	18598564	X	+	27260157	SF268	viability	TTCTGGATCGTTCTCCTTCAAGG	CDKL5	ENSG00000008086	0.538274882836156	[]	[]	8	hSpCas9	negative selection	2949067
18587954	18587977	X	+	27260157	SF268	viability	CGCTCCCTATGGAAAGTCCGTGG	CDKL5	ENSG00000008086	0.279416809538377	[]	[]	4	hSpCas9	negative selection	2949854
18575394	18575417	X	+	27260157	SF268	viability	AATGCTTCGGACTCTCAAGCAGG	CDKL5	ENSG00000008086	0.576127501834745	[]	[]	8	hSpCas9	negative selection	2950327
18603967	18603990	X	+	27260157	SF268	viability	ACCTGAGTGTAGGCCTGCCCCGG	CDKL5	ENSG00000008086	0.234981948116285	[]	[]	3	hSpCas9	negative selection	2951889
18598584	18598607	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAATGTGCTGCTTTCCACATGG	CDKL5	ENSG00000008086	-0.03568148799770862	[3,4]	[4,2]	0	hSpCas9	positive selection	2978253
18587958	18587981	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGTCCACGGACTTTCCATAGGG	CDKL5	ENSG00000008086	0.021974488319856572	[3,2]	[2,2]	0	hSpCas9	positive selection	2978254
18584306	18584329	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.12348900058585743	[5,5]	[4,4]	2	hSpCas9	positive selection	2978255
18603984	18604007	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAGACCTTCGTCAGCCCGGGG	CDKL5	ENSG00000008086	-1.3688487289289988	[2,1]	[0,0]	-9	hSpCas9	positive selection	2978256
18598584	18598607	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAATGTGCTGCTTTCCACATGG	CDKL5	ENSG00000008086	0.19817974235038113	[3,3]	[4,2]	3	hSpCas9	positive selection	3046111
18587958	18587981	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGTCCACGGACTTTCCATAGGG	CDKL5	ENSG00000008086	0.3308170536800151	[3,3]	[3,2]	6	hSpCas9	positive selection	3046112
18584306	18584329	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.38336561260763236	[5,5]	[5,4]	6	hSpCas9	positive selection	3046113
18603984	18604007	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAGACCTTCGTCAGCCCGGGG	CDKL5	ENSG00000008086	0.08996179004297944	[2,2]	[0,1]	1	hSpCas9	positive selection	3046114
18510823	18510846		-	24336571	A375	resistance to PLX after 7 days	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.293814569855263	[9,8]	[13,9]	7	hSpCas9	positive selection	3104677
18507141	18507164		-	24336571	A375	resistance to PLX after 7 days	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.29629398439824534	[16,14]	[13,11]	-8	hSpCas9	positive selection	3104678
18510833	18510856		+	24336571	A375	resistance to PLX after 7 days	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.048577173739226154	[11,9]	[11,10]	1	hSpCas9	positive selection	3104679
18507094	18507117		+	24336571	A375	resistance to PLX after 7 days	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	-0.10626119235260312	[29,36]	[29,30]	-3	hSpCas9	positive selection	3104680
18510823	18510846		-	24336571	A375	resistance to PLX after 14 days	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.011515510350171287	[10,10]	[5,2]	0	hSpCas9	positive selection	3162470
18507141	18507164		-	24336571	A375	resistance to PLX after 14 days	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.332545767077112	[17,12]	[4,5]	-4	hSpCas9	positive selection	3162471
18510833	18510856		+	24336571	A375	resistance to PLX after 14 days	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	1.2288080746840142	[9,13]	[10,15]	8	hSpCas9	positive selection	3162472
18507094	18507117		+	24336571	A375	resistance to PLX after 14 days	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	-0.14622905156279709	[32,25]	[13,9]	-1	hSpCas9	positive selection	3162473
18510823	18510846		-	24336571	A375	viability after 7 days	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	-0.6533443253451185	[15]	[9,8]	-7	hSpCas9	negative selection	3220263
18507141	18507164		-	24336571	A375	viability after 7 days	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.8833169032620074	[31]	[16,14]	-8	hSpCas9	negative selection	3220264
18510833	18510856		+	24336571	A375	viability after 7 days	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.057987121675240644	[10]	[11,9]	0	hSpCas9	negative selection	3220265
18507094	18507117		+	24336571	A375	viability after 7 days	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	-0.11367003918961638	[37]	[29,36]	-2	hSpCas9	negative selection	3220266
18510823	18510846		-	24336571	A375	viability after 14 days	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	-0.47618944576169075	[15]	[10,10]	-5	hSpCas9	negative selection	3278056
18507141	18507164		-	24336571	A375	viability after 14 days	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.9476340849784552	[31]	[17,12]	-8	hSpCas9	negative selection	3278057
18510833	18510856		+	24336571	A375	viability after 14 days	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.24329428341196607	[10]	[9,13]	3	hSpCas9	negative selection	3278058
18507094	18507117		+	24336571	A375	viability after 14 days	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	-0.26440668943331636	[37]	[32,25]	-3	hSpCas9	negative selection	3278059
18507094	18507117	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	-1.0034165585564916	[338,273]	[0,0]	-6	hSpCas9	positive selection	3342459
18507106	18507129	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	-0.716817870946318	[892,866]	[0,5]	-5	hSpCas9	positive selection	3342460
18510823	18510846	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	1.9168166908167468	[389,338]	[0,16]	7	hSpCas9	positive selection	3342461
18564473	18564496	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	-0.44311350669525723	[207,207]	[0,0]	-3	hSpCas9	positive selection	3361693
18510833	18510856	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.9374306429764127	[292,292]	[0,0]	-6	hSpCas9	positive selection	3361694
18564501	18564524	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.19123702098806272	[133,133]	[0,0]	1	hSpCas9	positive selection	3361695
18598584	18598607	X	-	26780180	HT29	viability (Avana library 4 designs)	ACAATGTGCTGCTTTCCACATGG	CDKL5	ENSG00000008086	0.595060305632765	[]	[]	2	hSpCas9	negative selection	3414566
18587958	18587981	X	-	26780180	HT29	viability (Avana library 4 designs)	ATGTCCACGGACTTTCCATAGGG	CDKL5	ENSG00000008086	1.47151261911903	[]	[]	6	hSpCas9	negative selection	3414567
18584305	18584328	X	+	26780180	HT29	viability (Avana library 4 designs)	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.00793532470233282	[]	[]	0	hSpCas9	negative selection	3414568
18603984	18604007	X	-	26780180	HT29	viability (Avana library 4 designs)	GGGAGACCTTCGTCAGCCCGGGG	CDKL5	ENSG00000008086	0.682065962552236	[]	[]	2	hSpCas9	negative selection	3414569
18598584	18598607	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAATGTGCTGCTTTCCACATGG	CDKL5	ENSG00000008086	1.76223551036185	[]	[]	2	hSpCas9	negative selection	3491146
18587958	18587981	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGTCCACGGACTTTCCATAGGG	CDKL5	ENSG00000008086	5.00754165033595	[]	[]	8	hSpCas9	negative selection	3491147
18584305	18584328	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	5.75044148030587	[]	[]	9	hSpCas9	negative selection	3491148
18603984	18604007	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAGACCTTCGTCAGCCCGGGG	CDKL5	ENSG00000008086	5.02309935950454	[]	[]	8	hSpCas9	negative selection	3491149
18579860	18579883	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGCTGGAAGAAATGCCAAATGG	CDKL5	ENSG00000008086	0.542273927107735	[]	[]	0	hSpCas9	negative selection	3491150
18507141	18507164	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.888207039934153	[]	[]	-1	hSpCas9	negative selection	3491151
18598584	18598607	X	-	26780180	A375	viability (Avana lentiGuide)	ACAATGTGCTGCTTTCCACATGG	CDKL5	ENSG00000008086	0.520654058772215	[]	[]	0	hSpCas9	negative selection	3599805
18587958	18587981	X	-	26780180	A375	viability (Avana lentiGuide)	ATGTCCACGGACTTTCCATAGGG	CDKL5	ENSG00000008086	-3.69412694375123	[]	[]	-6	hSpCas9	negative selection	3599806
18584305	18584328	X	+	26780180	A375	viability (Avana lentiGuide)	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	-3.48544073157753	[]	[]	-6	hSpCas9	negative selection	3599807
18603984	18604007	X	-	26780180	A375	viability (Avana lentiGuide)	GGGAGACCTTCGTCAGCCCGGGG	CDKL5	ENSG00000008086	8.33976297316109	[]	[]	6	hSpCas9	negative selection	3599808
18579860	18579883	X	+	26780180	A375	viability (Avana lentiGuide)	TTGCTGGAAGAAATGCCAAATGG	CDKL5	ENSG00000008086	-3.53226218569882	[]	[]	-6	hSpCas9	negative selection	3599809
18507141	18507164	X	-	26780180	A375	viability (Avana lentiGuide)	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-5.26211560863202	[]	[]	-8	hSpCas9	negative selection	3599810
18598584	18598607	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAATGTGCTGCTTTCCACATGG	CDKL5	ENSG00000008086	0.11571852972673229	[5]	[5,5]	3	hSpCas9	positive selection	3708464
18587958	18587981	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGTCCACGGACTTTCCATAGGG	CDKL5	ENSG00000008086	0.061251845192930636	[5]	[5,4]	1	hSpCas9	positive selection	3708465
18584305	18584328	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.22229681655930572	[5]	[6,6]	6	hSpCas9	positive selection	3708466
18603984	18604007	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAGACCTTCGTCAGCCCGGGG	CDKL5	ENSG00000008086	0.27386724467120876	[3]	[5,4]	7	hSpCas9	positive selection	3708467
18579860	18579883	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGCTGGAAGAAATGCCAAATGG	CDKL5	ENSG00000008086	-0.3354138275368325	[4]	[5,1]	-5	hSpCas9	positive selection	3708468
18507141	18507164	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.11158343116776798	[5]	[4,4]	-2	hSpCas9	positive selection	3708469
18598584	18598607	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAATGTGCTGCTTTCCACATGG	CDKL5	ENSG00000008086	0.3004901444214326	[5]	[6,5]	8	hSpCas9	positive selection	3817071
18587958	18587981	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGTCCACGGACTTTCCATAGGG	CDKL5	ENSG00000008086	-0.43665670441618143	[5]	[2,3]	-5	hSpCas9	positive selection	3817072
18584305	18584328	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.24315453225785633	[7]	[7,6]	6	hSpCas9	positive selection	3817073
18603984	18604007	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAGACCTTCGTCAGCCCGGGG	CDKL5	ENSG00000008086	-0.16305663381569674	[4]	[2,3]	-2	hSpCas9	positive selection	3817074
18579860	18579883	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGCTGGAAGAAATGCCAAATGG	CDKL5	ENSG00000008086	0.30815632309148633	[4]	[4,4]	8	hSpCas9	positive selection	3817075
18507141	18507164	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	0.3195027321052007	[5]	[6,5]	8	hSpCas9	positive selection	3817076
18564501	18564524	X	+	26780180	A375	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.615471028809362	[]	[]	2	hSpCas9	negative selection	3925253
18564473	18564496	X	+	26780180	A375	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.654611219913935	[]	[]	2	hSpCas9	negative selection	3925254
18510823	18510846	X	-	26780180	A375	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.464767851624952	[]	[]	1	hSpCas9	negative selection	3925255
18510833	18510856	X	+	26780180	A375	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	1.24644638051238	[]	[]	6	hSpCas9	negative selection	3925256
18507106	18507129	X	-	26780180	A375	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	-0.270846463625537	[]	[]	-7	hSpCas9	negative selection	3925257
18507094	18507117	X	+	26780180	A375	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.664858501210113	[]	[]	2	hSpCas9	negative selection	3925258
18564501	18564524	X	+	26780180	HT29	viability (GeCKOv2 library)	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.950175986251743	[]	[]	4	hSpCas9	negative selection	4033219
18564473	18564496	X	+	26780180	HT29	viability (GeCKOv2 library)	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	1.58922578083631	[]	[]	8	hSpCas9	negative selection	4033220
18510823	18510846	X	-	26780180	HT29	viability (GeCKOv2 library)	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.275000207237737	[]	[]	0	hSpCas9	negative selection	4033221
18510833	18510856	X	+	26780180	HT29	viability (GeCKOv2 library)	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	1.54830875461604	[]	[]	7	hSpCas9	negative selection	4033222
18507106	18507129	X	-	26780180	HT29	viability (GeCKOv2 library)	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	-0.263067099754177	[]	[]	-6	hSpCas9	negative selection	4033223
18507094	18507117	X	+	26780180	HT29	viability (GeCKOv2 library)	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.82078910539799	[]	[]	3	hSpCas9	negative selection	4033224
18510823	18510846	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	-0.10053133029301423	[3]	[1,2]	-2	hSpCas9	positive selection	4126706
18507141	18507164	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.02452130534288698	[3]	[2,2]	0	hSpCas9	positive selection	4126707
18510833	18510856	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.2474783648587574	[3]	[1,3]	6	hSpCas9	positive selection	4126708
18507094	18507117	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.10196074326806642	[4]	[3,3]	2	hSpCas9	positive selection	4126709
18510823	18510846	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.18269408142083746	[4]	[0,4,3,0]	1	hSpCas9	positive selection	4190728
18507141	18507164	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCTTCACCTACAACCCCAAGG	CDKL5	ENSG00000008086	-0.3923545410830005	[4]	[2,0,1,0]	-6	hSpCas9	positive selection	4190729
18510833	18510856	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.13546267227452552	[3]	[3,2,1,0]	1	hSpCas9	positive selection	4190730
18507094	18507117	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	1.0470860651098917	[4]	[3,5,3,4]	7	hSpCas9	positive selection	4190731
18507094	18507117	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.19015970757641387	[4]	[3,3]	4	hSpCas9	positive selection	4262515
18507106	18507129	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.44089527084847613	[5]	[5,5]	8	hSpCas9	positive selection	4262516
18510823	18510846	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.328181786197274	[4]	[4,3]	6	hSpCas9	positive selection	4262517
18564473	18564496	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.5523828915304356	[2]	[2,3]	9	hSpCas9	positive selection	4326793
18510833	18510856	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.01204805773440315	[3]	[3,1]	0	hSpCas9	positive selection	4326794
18564501	18564524	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	-0.058792851648402256	[2]	[3,0]	-1	hSpCas9	positive selection	4326795
18603905	18603927	X	-	27760321	OCIAML3	viability	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.44670186730634154	[818,772]	[840,859]	5	hSpCas9	negative selection	4388141
18604034	18604056	X	-	27760321	OCIAML3	viability	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.4926959693499093	[366,315]	[316,449]	6	hSpCas9	negative selection	4388142
18604435	18604457	X	-	27760321	OCIAML3	viability	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	-0.019760715675249937	[473,441]	[237,503]	0	hSpCas9	negative selection	4388143
18575435	18575457	X	+	27760321	OCIAML3	viability	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	0.8650637387079855	[491,393]	[494,799]	8	hSpCas9	negative selection	4388144
18584266	18584288	X	+	27760321	OCIAML3	viability	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.7161794997133438	[342,249]	[263,524]	8	hSpCas9	negative selection	4388145
18603905	18603927	X	-	27760321	OCIAML2	viability	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.7515650038061693	[818,772]	[1107,1054]	8	hSpCas9	negative selection	4471604
18604034	18604056	X	-	27760321	OCIAML2	viability	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	1.2512008365890597	[366,315]	[568,769]	9	hSpCas9	negative selection	4471605
18604435	18604457	X	-	27760321	OCIAML2	viability	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	0.3855318283086618	[473,441]	[453,523]	5	hSpCas9	negative selection	4471606
18575435	18575457	X	+	27760321	OCIAML2	viability	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	0.8043195949196449	[491,393]	[550,715]	9	hSpCas9	negative selection	4471607
18584266	18584288	X	+	27760321	OCIAML2	viability	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.13607216906714986	[342,249]	[169,380]	1	hSpCas9	negative selection	4471608
18603905	18603927	X	-	27760321	MV411	viability	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	1.1848337731089882	[818,772]	[1012,1468]	8	hSpCas9	negative selection	4555067
18604034	18604056	X	-	27760321	MV411	viability	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	-0.17722844387378522	[366,315]	[123,310]	-1	hSpCas9	negative selection	4555068
18604435	18604457	X	-	27760321	MV411	viability	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	0.889528905250085	[473,441]	[492,660]	6	hSpCas9	negative selection	4555069
18575435	18575457	X	+	27760321	MV411	viability	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	-0.9171203050017774	[491,393]	[49,309]	-6	hSpCas9	negative selection	4555070
18584266	18584288	X	+	27760321	MV411	viability	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	1.1907578469776292	[342,249]	[630,158]	8	hSpCas9	negative selection	4555071
18603905	18603927	X	-	27760321	HL60	viability	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.6237576368489764	[818,772]	[1146,849]	7	hSpCas9	negative selection	4638530
18604034	18604056	X	-	27760321	HL60	viability	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.6084539507999978	[366,315]	[410,437]	7	hSpCas9	negative selection	4638531
18604435	18604457	X	-	27760321	HL60	viability	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	0.7695207634454805	[473,441]	[738,530]	8	hSpCas9	negative selection	4638532
18575435	18575457	X	+	27760321	HL60	viability	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	0.6124505910071939	[491,393]	[501,600]	7	hSpCas9	negative selection	4638533
18584266	18584288	X	+	27760321	HL60	viability	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.6976498690021579	[342,249]	[423,351]	7	hSpCas9	negative selection	4638534
18603905	18603927	X	-	27760321	HT1080	viability	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	-0.4531154154070663	[772,602]	[235,160]	-2	hSpCas9	negative selection	4721993
18604034	18604056	X	-	27760321	HT1080	viability	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.3797576924144161	[315,246]	[196,89]	2	hSpCas9	negative selection	4721994
18604435	18604457	X	-	27760321	HT1080	viability	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	-1.075437913231142	[441,344]	[71,76]	-4	hSpCas9	negative selection	4721995
18575435	18575457	X	+	27760321	HT1080	viability	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	2.526351493244304	[393,307]	[597,1032]	9	hSpCas9	negative selection	4721996
18584266	18584288	X	+	27760321	HT1080	viability	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	2.5498186777938963	[249,194]	[613,414]	9	hSpCas9	negative selection	4721997
18603905	18603927	X	-	27760321	HT29	viability after 7 days	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.2209284299389802	[772,602]	[1342,832,961]	3	hSpCas9	negative selection	4805456
18604034	18604056	X	-	27760321	HT29	viability after 7 days	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.5918564169779534	[315,246]	[730,344,584]	8	hSpCas9	negative selection	4805457
18604435	18604457	X	-	27760321	HT29	viability after 7 days	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	-0.158019104482575	[441,344]	[500,492,374]	-2	hSpCas9	negative selection	4805458
18575435	18575457	X	+	27760321	HT29	viability after 7 days	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	-0.2349801607885254	[393,307]	[501,286,377]	-3	hSpCas9	negative selection	4805459
18584266	18584288	X	+	27760321	HT29	viability after 7 days	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.12178669080446647	[249,194]	[428,269,252]	1	hSpCas9	negative selection	4805460
18603905	18603927	X	-	27760321	HT29	viability after 25 days	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.5496657905113402	[772,602]	[1184,1221,1028]	6	hSpCas9	negative selection	4888919
18604034	18604056	X	-	27760321	HT29	viability after 25 days	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.9013285710821708	[315,246]	[543,655,605]	9	hSpCas9	negative selection	4888920
18604435	18604457	X	-	27760321	HT29	viability after 25 days	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	0.34731274163132225	[441,344]	[526,526,674]	3	hSpCas9	negative selection	4888921
18575435	18575457	X	+	27760321	HT29	viability after 25 days	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	-0.07483173263674775	[393,307]	[299,355,503]	-1	hSpCas9	negative selection	4888922
18584266	18584288	X	+	27760321	HT29	viability after 25 days	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	-0.022509731299193203	[249,194]	[212,297,240]	0	hSpCas9	negative selection	4888923
18603905	18603927	X	-	27760321	HT29	viability after 22 days	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.5382682500226048	[772,602]	[1239,1139,1081]	6	hSpCas9	negative selection	4972382
18604034	18604056	X	-	27760321	HT29	viability after 22 days	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	1.0806799192740086	[315,246]	[602,811,651]	9	hSpCas9	negative selection	4972383
18604435	18604457	X	-	27760321	HT29	viability after 22 days	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	0.5584717128715495	[441,344]	[717,569,720]	6	hSpCas9	negative selection	4972384
18575435	18575457	X	+	27760321	HT29	viability after 22 days	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	-0.15140957926453383	[393,307]	[234,358,506]	-1	hSpCas9	negative selection	4972385
18584266	18584288	X	+	27760321	HT29	viability after 22 days	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.18502913188164716	[249,194]	[185,410,282]	1	hSpCas9	negative selection	4972386
18603905	18603927	X	-	27760321	HT29	viability after 19 days	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.8142043496501046	[772,602]	[1230,1690,1217]	8	hSpCas9	negative selection	5055845
18604034	18604056	X	-	27760321	HT29	viability after 19 days	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.5985840058703109	[315,246]	[452,606,401]	6	hSpCas9	negative selection	5055846
18604435	18604457	X	-	27760321	HT29	viability after 19 days	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	0.23318875820452606	[441,344]	[467,737,379]	2	hSpCas9	negative selection	5055847
18575435	18575457	X	+	27760321	HT29	viability after 19 days	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	-0.07319085022274568	[393,307]	[446,391,314]	0	hSpCas9	negative selection	5055848
18584266	18584288	X	+	27760321	HT29	viability after 19 days	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	-0.018751372390351184	[249,194]	[311,230,217]	0	hSpCas9	negative selection	5055849
18603905	18603927	X	-	27760321	HT29	viability after 16 days	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.739019401248616	[772,602]	[1357,1275,1226]	8	hSpCas9	negative selection	5139308
18604034	18604056	X	-	27760321	HT29	viability after 16 days	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	1.029703339765193	[315,246]	[988,287,693]	9	hSpCas9	negative selection	5139309
18604435	18604457	X	-	27760321	HT29	viability after 16 days	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	0.051552855483828236	[441,344]	[440,543,379]	0	hSpCas9	negative selection	5139310
18575435	18575457	X	+	27760321	HT29	viability after 16 days	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	-0.2465752211655558	[393,307]	[293,275,420]	-3	hSpCas9	negative selection	5139311
18584266	18584288	X	+	27760321	HT29	viability after 16 days	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.14960737353849007	[249,194]	[354,305,173]	1	hSpCas9	negative selection	5139312
18603905	18603927	X	-	27760321	HT29	viability after 13 days	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.578525271811126	[772,602]	[1135,1562,894]	7	hSpCas9	negative selection	5222771
18604034	18604056	X	-	27760321	HT29	viability after 13 days	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.7702835672179799	[315,246]	[761,392,517]	8	hSpCas9	negative selection	5222772
18604435	18604457	X	-	27760321	HT29	viability after 13 days	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	-0.07108108787979359	[441,344]	[410,412,476]	-1	hSpCas9	negative selection	5222773
18575435	18575457	X	+	27760321	HT29	viability after 13 days	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	0.060652500373721	[393,307]	[320,556,397]	0	hSpCas9	negative selection	5222774
18584266	18584288	X	+	27760321	HT29	viability after 13 days	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.08261053915912397	[249,194]	[326,256,237]	1	hSpCas9	negative selection	5222775
18603905	18603927	X	-	27760321	HT29	viability after 10 days	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.5736169177163437	[772,602]	[1640,1217,980]	7	hSpCas9	negative selection	5306234
18604034	18604056	X	-	27760321	HT29	viability after 10 days	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	0.8238157914995181	[315,246]	[682,645,539]	9	hSpCas9	negative selection	5306235
18604435	18604457	X	-	27760321	HT29	viability after 10 days	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	-0.2744694570047873	[441,344]	[410,473,336]	-3	hSpCas9	negative selection	5306236
18575435	18575457	X	+	27760321	HT29	viability after 10 days	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	-0.6185091745666024	[393,307]	[416,198,238]	-6	hSpCas9	negative selection	5306237
18584266	18584288	X	+	27760321	HT29	viability after 10 days	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	0.5674231328148753	[249,194]	[519,244,463]	7	hSpCas9	negative selection	5306238
18603905	18603927	X	-	27760321	MOLM13	viability	AGCAGTACTTTTGCCGGCTTGG	CDKL5	ENSG00000008086	0.9248187031082234	[818,772]	[1298,473]	6	hSpCas9	negative selection	5389697
18604034	18604056	X	-	27760321	MOLM13	viability	ACTAAGACTAGCTCCAGCAAGG	CDKL5	ENSG00000008086	1.2203015556335852	[366,315]	[243,620]	8	hSpCas9	negative selection	5389698
18604435	18604457	X	-	27760321	MOLM13	viability	GGCTCCGCAATTTGGGCCCTGG	CDKL5	ENSG00000008086	1.150479597690142	[473,441]	[447,680]	7	hSpCas9	negative selection	5389699
18575435	18575457	X	+	27760321	MOLM13	viability	AGGAAGCATTTCGTCGGAGGGG	CDKL5	ENSG00000008086	1.0895725839797126	[491,393]	[685,394]	7	hSpCas9	negative selection	5389700
18584266	18584288	X	+	27760321	MOLM13	viability	TTGCTCGTAATCTGTCAGAAGG	CDKL5	ENSG00000008086	1.059703621751531	[342,249]	[548,171]	7	hSpCas9	negative selection	5389701
18425660	18425683	X	+	27661255	K562	viability	GTGGGGTCCCCTGCTAGAAGTGG	CDKL5	ENSG00000008086	0.1263623977647581	[2484,2405]	[2288,2000]	4	dCas9-KRAB	negative selection	5469968
18425663	18425686	X	+	27661255	K562	viability	GGGTCCCCTGCTAGAAGTGGGGG	CDKL5	ENSG00000008086	0.022113879844723128	[1187,1363]	[1127,950]	0	dCas9-KRAB	negative selection	5469969
18425672	18425695	X	+	27661255	K562	viability	GCTAGAAGTGGGGGACTCGGCGG	CDKL5	ENSG00000008086	-0.4282123959009472	[271,364]	[213,165]	-7	dCas9-KRAB	negative selection	5469970
18425667	18425690	X	-	27661255	K562	viability	GAGTCCCCCACTTCTAGCAGGGG	CDKL5	ENSG00000008086	0.12182803720646845	[897,1170]	[963,835]	4	dCas9-KRAB	negative selection	5469971
18426040	18426063	X	-	27661255	K562	viability	GGGAGCTCGTGCCGCGGGAGCGG	CDKL5	ENSG00000008086	0.20495985728284555	[914,766]	[853,710]	7	dCas9-KRAB	negative selection	5469972
18507094	18507117	X	+	27260156	BXPC3	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.17468167808016255	[1126]	[1290,1176,1336,1545]	4	hSpCas9	negative selection	5534975
18507106	18507129	X	-	27260156	BXPC3	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.3033366464784564	[2124]	[2524,2671,2453,3400]	6	hSpCas9	negative selection	5534976
18510823	18510846	X	-	27260156	BXPC3	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.30099926919138187	[1047]	[1077,1418,1374,1571]	6	hSpCas9	negative selection	5534977
18564473	18564496	X	+	27260156	BXPC3	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.4577794374850432	[387]	[740,405,480,587]	8	hSpCas9	negative selection	5599253
18510833	18510856	X	+	27260156	BXPC3	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.20079158152056586	[796]	[629,762,738,777]	-4	hSpCas9	negative selection	5599254
18564501	18564524	X	+	27260156	BXPC3	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.2803818238051844	[418]	[520,576,477,547]	6	hSpCas9	negative selection	5599255
18507094	18507117	X	+	27260156	A673	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.06138489604637498	[1126]	[1745,1321,1223,1394]	1	hSpCas9	negative selection	5656226
18507106	18507129	X	-	27260156	A673	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.25623539656909333	[2124]	[3289,2943,2940,3039]	6	hSpCas9	negative selection	5656227
18510823	18510846	X	-	27260156	A673	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.018339508714897867	[1047]	[1374,1189,1125,1427]	0	hSpCas9	negative selection	5656228
18564473	18564496	X	+	27260156	A673	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.07866857341517847	[387]	[546,447,465,514]	2	hSpCas9	negative selection	5720504
18510833	18510856	X	+	27260156	A673	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.04337928371819777	[796]	[964,781,936,1042]	-1	hSpCas9	negative selection	5720505
18564501	18564524	X	+	27260156	A673	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3065071906046599	[418]	[661,568,659,600]	7	hSpCas9	negative selection	5720506
18507094	18507117	X	+	27260156	A375	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.08305746578271589	[1126]	[1273,1527,1350,1431]	1	hSpCas9	negative selection	5777477
18507106	18507129	X	-	27260156	A375	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.4560522727629399	[2124]	[3304,3879,3293,3214]	6	hSpCas9	negative selection	5777478
18510823	18510846	X	-	27260156	A375	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.3604269812035017	[1047]	[1255,1757,1742,1548]	5	hSpCas9	negative selection	5777479
18564473	18564496	X	+	27260156	A375	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.38130316828908933	[387]	[467,713,527,656]	5	hSpCas9	negative selection	5841755
18510833	18510856	X	+	27260156	A375	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.0826295725447751	[796]	[563,1167,1163,678]	-1	hSpCas9	negative selection	5841756
18564501	18564524	X	+	27260156	A375	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.07525526575649649	[418]	[580,627,439,436]	1	hSpCas9	negative selection	5841757
18507094	18507117	X	+	27260156	COLO741	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.3241880570707767	[1126]	[1894,1491,2008]	6	hSpCas9	negative selection	5898728
18507106	18507129	X	-	27260156	COLO741	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.36312898344986744	[2124]	[4087,3604,2872]	7	hSpCas9	negative selection	5898729
18510823	18510846	X	-	27260156	COLO741	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.10293790815976989	[1047]	[1482,1578,1265]	2	hSpCas9	negative selection	5898730
18564473	18564496	X	+	27260156	COLO741	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.3447183724579153	[387]	[584,688,610]	7	hSpCas9	negative selection	5963006
18510833	18510856	X	+	27260156	COLO741	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.14973042010363125	[796]	[954,925,876]	-3	hSpCas9	negative selection	5963007
18564501	18564524	X	+	27260156	COLO741	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.19395265969574196	[418]	[590,657,586]	4	hSpCas9	negative selection	5963008
18507094	18507117	X	+	27260156	CAL120	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.13732964396899927	[1126]	[1686,1164,1791]	2	hSpCas9	negative selection	6019979
18507106	18507129	X	-	27260156	CAL120	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.5605271735471495	[2124]	[4646,3520,3646]	8	hSpCas9	negative selection	6019980
18510823	18510846	X	-	27260156	CAL120	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	-0.24131806285775126	[1047]	[1288,987,1060]	-4	hSpCas9	negative selection	6019981
18564473	18564496	X	+	27260156	CAL120	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.16726088267607378	[387]	[457,745,411]	2	hSpCas9	negative selection	6084257
18510833	18510856	X	+	27260156	CAL120	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.061587924513245684	[796]	[882,1148,810]	-1	hSpCas9	negative selection	6084258
18564501	18564524	X	+	27260156	CAL120	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.46121216837975143	[418]	[944,674,569]	7	hSpCas9	negative selection	6084259
18507094	18507117	X	+	27260156	CADOES1	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.26792880548074693	[1126]	[1270,992,1462,1322]	4	hSpCas9	negative selection	6141230
18507106	18507129	X	-	27260156	CADOES1	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.36207921583427893	[2124]	[2370,2369,2541,2890]	6	hSpCas9	negative selection	6141231
18510823	18510846	X	-	27260156	CADOES1	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.07180313711391784	[1047]	[956,942,987,1216]	1	hSpCas9	negative selection	6141232
18564473	18564496	X	+	27260156	CADOES1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.1642536188253677	[387]	[395,417,387,415]	3	hSpCas9	negative selection	6205508
18510833	18510856	X	+	27260156	CADOES1	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.12479121614181432	[796]	[640,870,1000,716]	2	hSpCas9	negative selection	6205509
18564501	18564524	X	+	27260156	CADOES1	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.0984252006605052	[418]	[419,379,393,476]	1	hSpCas9	negative selection	6205510
18507094	18507117	X	+	27260156	EWS502	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.19657884418550498	[1126]	[1080,1465,1477,1481]	3	hSpCas9	negative selection	6262481
18507106	18507129	X	-	27260156	EWS502	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.41275606303785795	[2124]	[2954,2839,3124,3071]	7	hSpCas9	negative selection	6262482
18510823	18510846	X	-	27260156	EWS502	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.14212947202624449	[1047]	[1337,1243,964,1337]	2	hSpCas9	negative selection	6262483
18564473	18564496	X	+	27260156	EWS502	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.2749587797244917	[387]	[495,446,436,616]	5	hSpCas9	negative selection	6326759
18510833	18510856	X	+	27260156	EWS502	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.0016594033396217789	[796]	[1154,533,1025,623]	0	hSpCas9	negative selection	6326760
18564501	18564524	X	+	27260156	EWS502	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.4357386152510685	[418]	[461,598,720,637]	7	hSpCas9	negative selection	6326761
18507094	18507117	X	+	27260156	EW8	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.2655042167963888	[1126]	[1249,1229,818,1153]	5	hSpCas9	negative selection	6383732
18507106	18507129	X	-	27260156	EW8	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.37990700500414354	[2124]	[2608,2165,2223,2001]	7	hSpCas9	negative selection	6383733
18510823	18510846	X	-	27260156	EW8	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.3983180047895687	[1047]	[1232,1083,1009,1177]	7	hSpCas9	negative selection	6383734
18564473	18564496	X	+	27260156	EW8	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.5147363559555003	[387]	[461,490,373,482]	8	hSpCas9	negative selection	6448010
18510833	18510856	X	+	27260156	EW8	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.05783694898473957	[796]	[536,724,608,811]	1	hSpCas9	negative selection	6448011
18564501	18564524	X	+	27260156	EW8	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.4021241438221803	[418]	[633,543,299,361]	7	hSpCas9	negative selection	6448012
18507094	18507117	X	+	27260156	CORL105	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.3525097885564632	[1126]	[1750,1269,2093,1696]	6	hSpCas9	negative selection	6504983
18507106	18507129	X	-	27260156	CORL105	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.4543049570833486	[2124]	[3148,3527,3684,3302]	8	hSpCas9	negative selection	6504984
18510823	18510846	X	-	27260156	CORL105	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.32106595363436297	[1047]	[1600,1353,1697,1508]	6	hSpCas9	negative selection	6504985
18564473	18564496	X	+	27260156	CORL105	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.14536200531242208	[387]	[446,541,504,512]	2	hSpCas9	negative selection	6569261
18510833	18510856	X	+	27260156	CORL105	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.1445146030205544	[796]	[806,769,1038,790]	-3	hSpCas9	negative selection	6569262
18564501	18564524	X	+	27260156	CORL105	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3242898187801786	[418]	[646,565,617,627]	6	hSpCas9	negative selection	6569263
18507094	18507117	X	+	27260156	HS294T	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.07706161287632596	[1126]	[413,409,335,727]	1	hSpCas9	negative selection	6626234
18507106	18507129	X	-	27260156	HS294T	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.6794095595990517	[2124]	[1371,1236,1311,1338]	8	hSpCas9	negative selection	6626235
18510823	18510846	X	-	27260156	HS294T	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.010920490761409551	[1047]	[397,390,377,477]	0	hSpCas9	negative selection	6626236
18564473	18564496	X	+	27260156	HS294T	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.12756242068980464	[387]	[135,170,218,124]	1	hSpCas9	negative selection	6690512
18510833	18510856	X	+	27260156	HS294T	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.15208045248796387	[796]	[478,263,276,336]	2	hSpCas9	negative selection	6690513
18564501	18564524	X	+	27260156	HS294T	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.19233411156959257	[418]	[188,148,165,246]	2	hSpCas9	negative selection	6690514
18507094	18507117	X	+	27260156	HCC44	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.1408087652657093	[1126]	[1244,1201,2086,1213]	2	hSpCas9	negative selection	6747485
18507106	18507129	X	-	27260156	HCC44	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.5538302256283516	[2124]	[4356,2878,4200,2949]	8	hSpCas9	negative selection	6747486
18510823	18510846	X	-	27260156	HCC44	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.06279985112877484	[1047]	[1212,1155,1529,1106]	1	hSpCas9	negative selection	6747487
18564473	18564496	X	+	27260156	HCC44	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.2564810071293853	[387]	[819,473,565,281]	4	hSpCas9	negative selection	6811763
18510833	18510856	X	+	27260156	HCC44	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.17248951758723152	[796]	[653,1443,1038,833]	2	hSpCas9	negative selection	6811764
18564501	18564524	X	+	27260156	HCC44	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3466283209617719	[418]	[634,452,811,566]	5	hSpCas9	negative selection	6811765
18507094	18507117	X	+	27260156	G402	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.1864099565543318	[1126]	[1464,2427,1317,1100]	2	hSpCas9	negative selection	6868736
18507106	18507129	X	-	27260156	G402	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.5611212788465862	[2124]	[3226,4303,3955,3745]	7	hSpCas9	negative selection	6868737
18510823	18510846	X	-	27260156	G402	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	-0.17728681782084932	[1047]	[1486,1078,878,1122]	-2	hSpCas9	negative selection	6868738
18564473	18564496	X	+	27260156	G402	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.3760949540884733	[387]	[797,543,419,710]	5	hSpCas9	negative selection	6933014
18510833	18510856	X	+	27260156	G402	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.4774712625526672	[796]	[1047,759,544,501]	-5	hSpCas9	negative selection	6933015
18564501	18564524	X	+	27260156	G402	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.24830182558561642	[418]	[765,596,391,689]	3	hSpCas9	negative selection	6933016
18507094	18507117	X	+	27260156	L33	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.26411092907132727	[1126]	[1319,551,920,1282]	5	hSpCas9	negative selection	6989987
18507106	18507129	X	-	27260156	L33	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.5074890474211635	[2124]	[3155,1243,1836,2964]	8	hSpCas9	negative selection	6989988
18510823	18510846	X	-	27260156	L33	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.0676864140003337	[1047]	[1039,446,679,1180]	1	hSpCas9	negative selection	6989989
18564473	18564496	X	+	27260156	L33	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	-0.21196510608605384	[387]	[336,127,211,352]	-5	hSpCas9	negative selection	7054265
18510833	18510856	X	+	27260156	L33	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.28547049332418795	[796]	[646,271,440,603]	-6	hSpCas9	negative selection	7054266
18564501	18564524	X	+	27260156	L33	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3996667010828338	[418]	[656,222,272,571]	8	hSpCas9	negative selection	7054267
18507094	18507117	X	+	27260156	K562	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.21536558019873442	[1126]	[1502,1366,1029,818]	2	hSpCas9	negative selection	7111238
18507106	18507129	X	-	27260156	K562	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.6657997727370204	[2124]	[3243,3060,3442,2310]	8	hSpCas9	negative selection	7111239
18510823	18510846	X	-	27260156	K562	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.2818511704689788	[1047]	[1053,1084,1180,1182]	3	hSpCas9	negative selection	7111240
18564473	18564496	X	+	27260156	K562	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.22446218693892647	[387]	[379,459,350,415]	3	hSpCas9	negative selection	7175516
18510833	18510856	X	+	27260156	K562	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.38004235300586847	[796]	[827,409,397,550]	-5	hSpCas9	negative selection	7175517
18564501	18564524	X	+	27260156	K562	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.2565642316720707	[418]	[443,578,531,249]	3	hSpCas9	negative selection	7175518
18507094	18507117	X	+	27260156	HT29	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.16541796819803167	[1126]	[1581,1796,1438,1363]	3	hSpCas9	negative selection	7232489
18507106	18507129	X	-	27260156	HT29	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.42247909839472486	[2124]	[3922,3674,3286,3043]	7	hSpCas9	negative selection	7232490
18510823	18510846	X	-	27260156	HT29	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.09893455823825104	[1047]	[1438,1323,1547,1163]	2	hSpCas9	negative selection	7232491
18564473	18564496	X	+	27260156	HT29	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.15124855792783012	[387]	[659,490,531,427]	3	hSpCas9	negative selection	7296767
18510833	18510856	X	+	27260156	HT29	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.1884257980050481	[796]	[815,863,869,843]	-4	hSpCas9	negative selection	7296768
18564501	18564524	X	+	27260156	HT29	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.09469738977515009	[418]	[658,499,655,381]	1	hSpCas9	negative selection	7296769
18507094	18507117	X	+	27260156	MHHES1	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.4174921349977063	[1126]	[1891,1997,1648,1340]	7	hSpCas9	negative selection	7353740
18507106	18507129	X	-	27260156	MHHES1	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.4301253790557076	[2124]	[3575,3700,3481,2361]	7	hSpCas9	negative selection	7353741
18510823	18510846	X	-	27260156	MHHES1	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.45156254967461695	[1047]	[2037,1733,1321,1429]	7	hSpCas9	negative selection	7353742
18564473	18564496	X	+	27260156	MHHES1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.41044006313600345	[387]	[839,764,469,340]	7	hSpCas9	negative selection	7418018
18510833	18510856	X	+	27260156	MHHES1	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.26423560380791933	[796]	[1121,1148,1269,820]	5	hSpCas9	negative selection	7418019
18564501	18564524	X	+	27260156	MHHES1	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.4365843904635657	[418]	[598,686,565,677]	7	hSpCas9	negative selection	7418020
18507094	18507117	X	+	27260156	MEWO	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.12845913239694529	[1126]	[1368,1024,1105]	3	hSpCas9	negative selection	7474991
18507106	18507129	X	-	27260156	MEWO	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.3763704636002507	[2124]	[2842,2420,2528]	7	hSpCas9	negative selection	7474992
18510823	18510846	X	-	27260156	MEWO	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.22462220899770413	[1047]	[1338,971,1163]	5	hSpCas9	negative selection	7474993
18564473	18564496	X	+	27260156	MEWO	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.1423193593861984	[387]	[390,388,419]	3	hSpCas9	negative selection	7539269
18510833	18510856	X	+	27260156	MEWO	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.22886737853638817	[796]	[561,687,643]	-5	hSpCas9	negative selection	7539270
18564501	18564524	X	+	27260156	MEWO	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3194313465169405	[418]	[643,355,497]	6	hSpCas9	negative selection	7539271
18507094	18507117	X	+	27260156	LNCAPCLONEFGC	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.15538484957065823	[1126]	[1047,1100,1390,1048]	2	hSpCas9	negative selection	7596242
18507106	18507129	X	-	27260156	LNCAPCLONEFGC	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.5723973261057673	[2124]	[3194,2489,2951,2841]	8	hSpCas9	negative selection	7596243
18510823	18510846	X	-	27260156	LNCAPCLONEFGC	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.09758713166075217	[1047]	[885,1129,1046,998]	1	hSpCas9	negative selection	7596244
18564473	18564496	X	+	27260156	LNCAPCLONEFGC	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.7526234801600136	[387]	[686,400,705,601]	9	hSpCas9	negative selection	7660520
18510833	18510856	X	+	27260156	LNCAPCLONEFGC	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.12176603178858669	[796]	[528,552,955,668]	-2	hSpCas9	negative selection	7660521
18564501	18564524	X	+	27260156	LNCAPCLONEFGC	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.435509500485352	[418]	[482,411,518,646]	6	hSpCas9	negative selection	7660522
18507094	18507117	X	+	27260156	PANC0327	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.4079767507606309	[1126]	[1215,1880,1055,1078]	6	hSpCas9	negative selection	7717493
18507106	18507129	X	-	27260156	PANC0327	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.5489347858170168	[2124]	[2087,2670,2869,3372]	7	hSpCas9	negative selection	7717494
18510823	18510846	X	-	27260156	PANC0327	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.4567027216274737	[1047]	[1159,1203,1328,1416]	6	hSpCas9	negative selection	7717495
18564473	18564496	X	+	27260156	PANC0327	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.4265069671598163	[387]	[318,608,414,478]	6	hSpCas9	negative selection	7781771
18510833	18510856	X	+	27260156	PANC0327	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.028541660857825946	[796]	[782,635,986,498]	0	hSpCas9	negative selection	7781772
18564501	18564524	X	+	27260156	PANC0327	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.28289163248960325	[418]	[578,454,311,474]	4	hSpCas9	negative selection	7781773
18507094	18507117	X	+	27260156	NCIH2009	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.006126016538608781	[1126]	[1840,1114,1844]	0	hSpCas9	negative selection	7838744
18507106	18507129	X	-	27260156	NCIH2009	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.6029373694771571	[2124]	[5253,3922,4500]	8	hSpCas9	negative selection	7838745
18510823	18510846	X	-	27260156	NCIH2009	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.28783885535147413	[1047]	[2148,1512,1773]	4	hSpCas9	negative selection	7838746
18564473	18564496	X	+	27260156	NCIH2009	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.08768769767107418	[387]	[666,586,490]	1	hSpCas9	negative selection	7903022
18510833	18510856	X	+	27260156	NCIH2009	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.24311110324408547	[796]	[1192,818,860]	-3	hSpCas9	negative selection	7903023
18564501	18564524	X	+	27260156	NCIH2009	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3488028706997515	[418]	[898,614,753]	5	hSpCas9	negative selection	7903024
18507094	18507117	X	+	27260156	NCIH1373	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.3291731651199905	[1126]	[1988,1196,1284,526]	3	hSpCas9	negative selection	7959995
18507106	18507129	X	-	27260156	NCIH1373	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	1.1668371644290558	[2124]	[5547,4694,4431,1813]	9	hSpCas9	negative selection	7959996
18510823	18510846	X	-	27260156	NCIH1373	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.6320309232169585	[1047]	[2139,1227,2201,474]	6	hSpCas9	negative selection	7959997
18564473	18564496	X	+	27260156	NCIH1373	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.17206804353807698	[387]	[670,413,275,169]	1	hSpCas9	negative selection	8024273
18510833	18510856	X	+	27260156	NCIH1373	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.05857201742927054	[796]	[1279,562,951,188]	0	hSpCas9	negative selection	8024274
18564501	18564524	X	+	27260156	NCIH1373	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.2944933545504179	[418]	[448,640,618,147]	3	hSpCas9	negative selection	8024275
18507094	18507117	X	+	27260156	PATU8902	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.4826315029095576	[1126]	[1923,2157,2187,2529]	5	hSpCas9	negative selection	8081246
18507106	18507129	X	-	27260156	PATU8902	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.6281936708396092	[2124]	[6132,4840,2877,4863]	6	hSpCas9	negative selection	8081247
18510823	18510846	X	-	27260156	PATU8902	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.14786016948421987	[1047]	[1462,1762,1675,1529]	1	hSpCas9	negative selection	8081248
18564473	18564496	X	+	27260156	PATU8902	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.32683299834603863	[387]	[652,602,650,822]	3	hSpCas9	negative selection	8145524
18510833	18510856	X	+	27260156	PATU8902	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.2579669411846771	[796]	[1184,1049,1364,1738]	2	hSpCas9	negative selection	8145525
18564501	18564524	X	+	27260156	PATU8902	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.5607565400096514	[418]	[1028,626,576,1329]	6	hSpCas9	negative selection	8145526
18507094	18507117	X	+	27260156	PANC1	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.39026784866935293	[1126]	[1256,1532,1152,1178]	6	hSpCas9	negative selection	8202497
18507106	18507129	X	-	27260156	PANC1	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.6067107062066506	[2124]	[2678,3813,2826,2082]	8	hSpCas9	negative selection	8202498
18510823	18510846	X	-	27260156	PANC1	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.46026236809922905	[1047]	[1082,1741,1248,1004]	7	hSpCas9	negative selection	8202499
18564473	18564496	X	+	27260156	PANC1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.3225394748255945	[387]	[412,380,574,303]	5	hSpCas9	negative selection	8266775
18510833	18510856	X	+	27260156	PANC1	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.2392838943105544	[796]	[748,613,563,413]	-4	hSpCas9	negative selection	8266776
18564501	18564524	X	+	27260156	PANC1	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.5865689039332246	[418]	[636,597,431,500]	8	hSpCas9	negative selection	8266777
18507094	18507117	X	+	27260156	PANC0813	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.30693777160997193	[1126]	[1290,1575,1879,1762]	5	hSpCas9	negative selection	8323748
18507106	18507129	X	-	27260156	PANC0813	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.5703066368401353	[2124]	[3537,4061,3541,3662]	8	hSpCas9	negative selection	8323749
18510823	18510846	X	-	27260156	PANC0813	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.2504200651350452	[1047]	[1526,1465,1050,1795]	4	hSpCas9	negative selection	8323750
18564473	18564496	X	+	27260156	PANC0813	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.2675106642789144	[387]	[500,462,628,593]	4	hSpCas9	negative selection	8388026
18510833	18510856	X	+	27260156	PANC0813	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.31770067777628286	[796]	[915,975,482,647]	-5	hSpCas9	negative selection	8388027
18564501	18564524	X	+	27260156	PANC0813	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.5381535812169338	[418]	[748,575,866,671]	8	hSpCas9	negative selection	8388028
18507094	18507117	X	+	27260156	RDES	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.16640553276355563	[1126]	[984,1347,1649,1997]	2	hSpCas9	negative selection	8444999
18507106	18507129	X	-	27260156	RDES	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.4588930900147896	[2124]	[2566,3372,3653,4024]	7	hSpCas9	negative selection	8445000
18510823	18510846	X	-	27260156	RDES	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.11752497726720912	[1047]	[1068,1104,1342,1825]	2	hSpCas9	negative selection	8445001
18564473	18564496	X	+	27260156	RDES	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.33956312969561286	[387]	[442,517,663,666]	5	hSpCas9	negative selection	8509277
18510833	18510856	X	+	27260156	RDES	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.22441862808103907	[796]	[697,711,796,958]	-4	hSpCas9	negative selection	8509278
18564501	18564524	X	+	27260156	RDES	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.20735175160126168	[418]	[482,482,552,739]	3	hSpCas9	negative selection	8509279
18507094	18507117	X	+	27260156	PC3	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.2243217762907963	[1126]	[747,1524,2349,1138]	5	hSpCas9	negative selection	8566250
18507106	18507129	X	-	27260156	PC3	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.34111180196277013	[2124]	[1797,2325,4575,2912]	7	hSpCas9	negative selection	8566251
18510823	18510846	X	-	27260156	PC3	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.19328907975967824	[1047]	[786,1064,2086,1253]	4	hSpCas9	negative selection	8566252
18564473	18564496	X	+	27260156	PC3	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.14763490567527598	[387]	[319,363,681,449]	3	hSpCas9	negative selection	8630528
18510833	18510856	X	+	27260156	PC3	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.43796303874758347	[796]	[459,517,701,704]	-7	hSpCas9	negative selection	8630529
18564501	18564524	X	+	27260156	PC3	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3877342348638212	[418]	[288,426,1097,666]	7	hSpCas9	negative selection	8630530
18507094	18507117	X	+	27260156	PATU8988T	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.22791951572406455	[1126]	[979,1437,1103,1624]	4	hSpCas9	negative selection	8687501
18507106	18507129	X	-	27260156	PATU8988T	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.43667733356617644	[2124]	[2638,3326,2207,3020]	7	hSpCas9	negative selection	8687502
18510823	18510846	X	-	27260156	PATU8988T	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.04309765929685394	[1047]	[1132,942,1053,1032]	0	hSpCas9	negative selection	8687503
18564473	18564496	X	+	27260156	PATU8988T	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.6000845591927007	[387]	[824,470,473,488]	8	hSpCas9	negative selection	8751779
18510833	18510856	X	+	27260156	PATU8988T	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.43720003205850844	[796]	[663,602,512,492]	-6	hSpCas9	negative selection	8751780
18564501	18564524	X	+	27260156	PATU8988T	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.39564394650293155	[418]	[408,462,465,808]	6	hSpCas9	negative selection	8751781
18507094	18507117	X	+	27260156	T47D	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.27275031961155105	[1126]	[1702,1428,1547,1681]	6	hSpCas9	negative selection	8808752
18507106	18507129	X	-	27260156	T47D	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.40814680640402834	[2124]	[3387,2972,3437,3367]	8	hSpCas9	negative selection	8808753
18510823	18510846	X	-	27260156	T47D	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.22306521704332116	[1047]	[1589,1260,1326,1541]	5	hSpCas9	negative selection	8808754
18564473	18564496	X	+	27260156	T47D	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.3220754768658575	[387]	[511,545,604,598]	6	hSpCas9	negative selection	8873030
18510833	18510856	X	+	27260156	T47D	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.032079307033444415	[796]	[791,920,820,1103]	0	hSpCas9	negative selection	8873031
18564501	18564524	X	+	27260156	T47D	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.2260740621550689	[418]	[607,498,516,669]	5	hSpCas9	negative selection	8873032
18507094	18507117	X	+	27260156	SU8686	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.20792127244876224	[1126]	[1055,1218,1397,1562]	3	hSpCas9	negative selection	8930003
18507106	18507129	X	-	27260156	SU8686	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.6223928508520897	[2124]	[3064,2593,3535,3987]	9	hSpCas9	negative selection	8930004
18510823	18510846	X	-	27260156	SU8686	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.20437882892307435	[1047]	[1137,932,1643,1102]	3	hSpCas9	negative selection	8930005
18564473	18564496	X	+	27260156	SU8686	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.13844876374298945	[387]	[349,334,361,707]	2	hSpCas9	negative selection	8994281
18510833	18510856	X	+	27260156	SU8686	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.037930196049549614	[796]	[652,666,844,1169]	0	hSpCas9	negative selection	8994282
18564501	18564524	X	+	27260156	SU8686	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.17018030270877332	[418]	[436,380,434,657]	3	hSpCas9	negative selection	8994283
18507094	18507117	X	+	27260156	SKES1	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.20298817064749564	[1126]	[1384,1363,1344,1110]	4	hSpCas9	negative selection	9051254
18507106	18507129	X	-	27260156	SKES1	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.2847433792335119	[2124]	[2651,2990,2511,2246]	6	hSpCas9	negative selection	9051255
18510823	18510846	X	-	27260156	SKES1	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.18375483684423388	[1047]	[1357,1164,1227,1025]	4	hSpCas9	negative selection	9051256
18564473	18564496	X	+	27260156	SKES1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.21685098964421612	[387]	[420,590,410,391]	4	hSpCas9	negative selection	9115532
18510833	18510856	X	+	27260156	SKES1	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.04430389505148502	[796]	[884,846,807,582]	-1	hSpCas9	negative selection	9115533
18564501	18564524	X	+	27260156	SKES1	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3936298966186531	[418]	[884,477,541,347]	7	hSpCas9	negative selection	9115534
18507094	18507117	X	+	27260156	TOV112D	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.10582381604479885	[1126]	[1290,1624,1013,1038]	2	hSpCas9	negative selection	9172505
18507106	18507129	X	-	27260156	TOV112D	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.19328134245678852	[2124]	[2581,3142,1948,2247]	4	hSpCas9	negative selection	9172506
18510823	18510846	X	-	27260156	TOV112D	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	-0.0270530817283674	[1047]	[821,1248,1302,787]	0	hSpCas9	negative selection	9172507
18564473	18564496	X	+	27260156	TOV112D	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.22750402024482153	[387]	[712,428,400,295]	4	hSpCas9	negative selection	9236783
18510833	18510856	X	+	27260156	TOV112D	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	0.03731416189132297	[796]	[773,676,1130,658]	0	hSpCas9	negative selection	9236784
18564501	18564524	X	+	27260156	TOV112D	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.3740486516528242	[418]	[622,691,479,425]	7	hSpCas9	negative selection	9236785
18507094	18507117	X	+	27260156	TC71	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.2010993555706031	[1126]	[1352,1388,1260,1567]	5	hSpCas9	negative selection	9293756
18507106	18507129	X	-	27260156	TC71	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.37757713494774947	[2124]	[3007,2774,3045,3006]	8	hSpCas9	negative selection	9293757
18510823	18510846	X	-	27260156	TC71	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.1552825861459699	[1047]	[1086,1378,1224,1321]	4	hSpCas9	negative selection	9293758
18564473	18564496	X	+	27260156	TC71	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.10620400395956686	[387]	[496,413,392,489]	2	hSpCas9	negative selection	9358034
18510833	18510856	X	+	27260156	TC71	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.12469895362321681	[796]	[812,837,714,768]	-3	hSpCas9	negative selection	9358035
18564501	18564524	X	+	27260156	TC71	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.12057010196872951	[418]	[480,417,511,544]	3	hSpCas9	negative selection	9358036
18507094	18507117	X	+	27260156	TC32	viability	TTCATGAAGATTCCTAACATTGG	CDKL5	ENSG00000008086	0.29477502752900975	[1126]	[1058,1041,1819,1423]	5	hSpCas9	negative selection	9415007
18507106	18507129	X	-	27260156	TC32	viability	TTCATCACATTACCAATGTTAGG	CDKL5	ENSG00000008086	0.22691914629646792	[2124]	[2122,1642,3389,2540]	4	hSpCas9	negative selection	9415008
18510823	18510846	X	-	27260156	TC32	viability	GCATTTAAGTACAACTCCATAGG	CDKL5	ENSG00000008086	0.1499614401354683	[1047]	[955,1045,1048,1287]	2	hSpCas9	negative selection	9415009
18564473	18564496	X	+	27260156	TC32	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.14081833855732168	[387]	[428,184,532,548]	2	hSpCas9	negative selection	9479285
18510833	18510856	X	+	27260156	TC32	viability	TGTACTTAAATGCAGACACAAGG	CDKL5	ENSG00000008086	-0.46067594674018236	[796]	[538,388,743,567]	-7	hSpCas9	negative selection	9479286
18564501	18564524	X	+	27260156	TC32	viability	AAGAAATTCAAGGACAGTGAAGG	CDKL5	ENSG00000008086	0.23237443458657608	[418]	[360,293,639,647]	4	hSpCas9	negative selection	9479287
18575433	18575456	X	+	27869803	HPAFII	viability after 27 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.8272299290432346	[45]	[37,46,NaN]	6	hSpCas9	negative selection	9608373
18584305	18584328	X	+	27869803	HPAFII	viability after 27 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.7116678047556704	[275]	[331,158,NaN]	6	hSpCas9	negative selection	9608374
18588131	18588154	X	-	27869803	HPAFII	viability after 27 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	1.9350132118822203	[87]	[153,195,NaN]	9	hSpCas9	negative selection	9608375
18595362	18595385	X	-	27869803	HPAFII	viability after 27 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.0513158227979482	[133]	[229,75,NaN]	8	hSpCas9	negative selection	9608376
18598480	18598503	X	-	27869803	HPAFII	viability after 27 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.8180725606361398	[147]	[242,48,NaN]	6	hSpCas9	negative selection	9608377
18604634	18604657	X	+	27869803	HPAFII	viability after 27 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.4123131775917871	[134]	[112,78,NaN]	3	hSpCas9	negative selection	9608378
18575433	18575456	X	+	27869803	HPAFII	viability after 15 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.08496037972273	[45]	[168,64,NaN]	9	hSpCas9	negative selection	9690822
18584305	18584328	X	+	27869803	HPAFII	viability after 15 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.3293025078409484	[275]	[532,272,NaN]	4	hSpCas9	negative selection	9690823
18588131	18588154	X	-	27869803	HPAFII	viability after 15 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	1.0317428293499584	[87]	[127,233,NaN]	9	hSpCas9	negative selection	9690824
18595362	18595385	X	-	27869803	HPAFII	viability after 15 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.5838324362500413	[133]	[406,96,NaN]	6	hSpCas9	negative selection	9690825
18598480	18598503	X	-	27869803	HPAFII	viability after 15 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.4913646878030193	[147]	[423,98,NaN]	5	hSpCas9	negative selection	9690826
18604634	18604657	X	+	27869803	HPAFII	viability after 15 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.6890082984055687	[134]	[318,180,NaN]	7	hSpCas9	negative selection	9690827
18575433	18575456	X	+	27869803	ASPC1	viability after 36 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	-0.4207053659073887	[231]	[41,150,0]	-4	hSpCas9	negative selection	9773271
18584305	18584328	X	+	27869803	ASPC1	viability after 36 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.5568156966985273	[556]	[358,184,311]	5	hSpCas9	negative selection	9773272
18588131	18588154	X	-	27869803	ASPC1	viability after 36 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	0.5805254468954165	[341]	[140,146,227]	6	hSpCas9	negative selection	9773273
18595362	18595385	X	-	27869803	ASPC1	viability after 36 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.7894600867005086	[252]	[230,153,94]	7	hSpCas9	negative selection	9773274
18598480	18598503	X	-	27869803	ASPC1	viability after 36 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.2667610363910907	[273]	[43,280,31]	2	hSpCas9	negative selection	9773275
18604634	18604657	X	+	27869803	ASPC1	viability after 36 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.22973060134882417	[389]	[144,102,104]	-2	hSpCas9	negative selection	9773276
18575433	18575456	X	+	27869803	PATU8988S	viability after 35 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.8086414588076456	[89]	[58,67,NaN]	8	hSpCas9	negative selection	9855720
18584305	18584328	X	+	27869803	PATU8988S	viability after 35 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.23259746831808073	[571]	[347,192,NaN]	2	hSpCas9	negative selection	9855721
18588131	18588154	X	-	27869803	PATU8988S	viability after 35 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-1.442477995776366	[279]	[37,44,NaN]	-8	hSpCas9	negative selection	9855722
18595362	18595385	X	-	27869803	PATU8988S	viability after 35 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.6200332202936716	[231]	[189,96,NaN]	6	hSpCas9	negative selection	9855723
18598480	18598503	X	-	27869803	PATU8988S	viability after 35 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	1.1253934401016887	[355]	[223,401,NaN]	9	hSpCas9	negative selection	9855724
18604634	18604657	X	+	27869803	PATU8988S	viability after 35 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.08742228809218122	[327]	[51,196,NaN]	-1	hSpCas9	negative selection	9855725
18575433	18575456	X	+	27869803	PATU8988S	viability after 31 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	0.7681374900026645	[89]	[50,73,NaN]	8	hSpCas9	negative selection	9938169
18584305	18584328	X	+	27869803	PATU8988S	viability after 31 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.3111038125552129	[571]	[333,217,NaN]	4	hSpCas9	negative selection	9938170
18588131	18588154	X	-	27869803	PATU8988S	viability after 31 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	-0.7044256026123105	[279]	[53,86,NaN]	-6	hSpCas9	negative selection	9938171
18595362	18595385	X	-	27869803	PATU8988S	viability after 31 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	0.6499962641105131	[231]	[149,138,NaN]	7	hSpCas9	negative selection	9938172
18598480	18598503	X	-	27869803	PATU8988S	viability after 31 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.5830146523622799	[355]	[220,201,NaN]	7	hSpCas9	negative selection	9938173
18604634	18604657	X	+	27869803	PATU8988S	viability after 31 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	-0.24402625982879744	[327]	[87,138,NaN]	-3	hSpCas9	negative selection	9938174
18575433	18575456	X	+	27869803	HPAFII	viability after 35 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.1707613137411024	[45]	[82,17,NaN]	7	hSpCas9	negative selection	10020618
18584305	18584328	X	+	27869803	HPAFII	viability after 35 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.6542238058459178	[275]	[241,194,NaN]	4	hSpCas9	negative selection	10020619
18588131	18588154	X	-	27869803	HPAFII	viability after 35 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	1.8353246905023903	[87]	[110,212,NaN]	9	hSpCas9	negative selection	10020620
18595362	18595385	X	-	27869803	HPAFII	viability after 35 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.3907072871911077	[133]	[278,63,NaN]	8	hSpCas9	negative selection	10020621
18598480	18598503	X	-	27869803	HPAFII	viability after 35 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.6771954415487496	[147]	[203,24,NaN]	4	hSpCas9	negative selection	10020622
18604634	18604657	X	+	27869803	HPAFII	viability after 35 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.5405501608317858	[134]	[89,109,NaN]	3	hSpCas9	negative selection	10020623
18575433	18575456	X	+	27869803	HPAFII	viability after 31 days	GAAGGAAGCATTTCGTCGGAGGG	CDKL5	ENSG00000008086	1.7343954698693458	[45]	[105,63,NaN]	9	hSpCas9	negative selection	10103067
18584305	18584328	X	+	27869803	HPAFII	viability after 31 days	CAGAGTACGTTGCCACCAGATGG	CDKL5	ENSG00000008086	0.9244139312013981	[275]	[259,330,NaN]	7	hSpCas9	negative selection	10103068
18588131	18588154	X	-	27869803	HPAFII	viability after 31 days	AACCTCTTACCCGGAGCCCATGG	CDKL5	ENSG00000008086	1.990330888095128	[87]	[111,287,NaN]	9	hSpCas9	negative selection	10103069
18595362	18595385	X	-	27869803	HPAFII	viability after 31 days	TTCTTTCCAAGGACTGAGGATGG	CDKL5	ENSG00000008086	1.961018557633719	[133]	[410,163,NaN]	9	hSpCas9	negative selection	10103070
18598480	18598503	X	-	27869803	HPAFII	viability after 31 days	TCTGTCAAGTATCTGTCAGCTGG	CDKL5	ENSG00000008086	0.790547210482927	[147]	[247,29,NaN]	6	hSpCas9	negative selection	10103071
18604634	18604657	X	+	27869803	HPAFII	viability after 31 days	ATTGAAGCTGCCGGAGCACATGG	CDKL5	ENSG00000008086	0.3253260698429973	[134]	[70,120,NaN]	2	hSpCas9	negative selection	10103072
18587997	18588020	X	+	28162770	P31FUJ	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.4573185262921602	[312]	[504]	5	hSpCas9	negative selection	10130860
18603957	18603980	X	+	28162770	P31FUJ	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.10319300260853381	[346]	[437]	1	hSpCas9	negative selection	10130861
18604371	18604394	X	+	28162770	P31FUJ	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	1.0302322014194154	[49]	[119]	9	hSpCas9	negative selection	10130862
18604804	18604827	X	+	28162770	P31FUJ	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.6689337792707555	[242]	[453]	7	hSpCas9	negative selection	10130863
18609549	18609572	X	+	28162770	P31FUJ	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.2255627265285658	[122]	[168]	2	hSpCas9	negative selection	10130864
18613154	18613177	X	-	28162770	P31FUJ	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.36057253612297757	[341]	[515]	4	hSpCas9	negative selection	10130865
18625192	18625215	X	+	28162770	P31FUJ	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	1.087275094785042	[311]	[778]	9	hSpCas9	negative selection	10130866
18628526	18628549	X	+	28162770	P31FUJ	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.02844370590819234	[137]	[158]	0	hSpCas9	negative selection	10130867
18564473	18564496	X	+	28162770	P31FUJ	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.4827539994928407	[963]	[1582]	5	hSpCas9	negative selection	10130868
18584317	18584340	X	-	28162770	P31FUJ	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.5311725100848067	[380]	[646]	6	hSpCas9	negative selection	10130869
18587997	18588020	X	+	28162770	TF1	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	NaN	[NaN]	[496]	1	hSpCas9	negative selection	10300226
18603957	18603980	X	+	28162770	TF1	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	NaN	[NaN]	[463]	1	hSpCas9	negative selection	10300227
18604371	18604394	X	+	28162770	TF1	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10300228
18604804	18604827	X	+	28162770	TF1	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	NaN	[NaN]	[532]	1	hSpCas9	negative selection	10300229
18609549	18609572	X	+	28162770	TF1	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10300230
18613154	18613177	X	-	28162770	TF1	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	NaN	[NaN]	[584]	1	hSpCas9	negative selection	10300231
18625192	18625215	X	+	28162770	TF1	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	NaN	[NaN]	[490]	1	hSpCas9	negative selection	10300232
18628526	18628549	X	+	28162770	TF1	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10300233
18564473	18564496	X	+	28162770	TF1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	NaN	[NaN]	[1186]	1	hSpCas9	negative selection	10300234
18584317	18584340	X	-	28162770	TF1	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	NaN	[NaN]	[446]	1	hSpCas9	negative selection	10300235
18587997	18588020	X	+	28162770	SKM1	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.21547300739665726	[75]	[155]	2	hSpCas9	negative selection	10469592
18603957	18603980	X	+	28162770	SKM1	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.30280475771427506	[82]	[180]	3	hSpCas9	negative selection	10469593
18604371	18604394	X	+	28162770	SKM1	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	-0.2914869813232257	[17]	[25]	-2	hSpCas9	negative selection	10469594
18604804	18604827	X	+	28162770	SKM1	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	1.0625210845580586	[90]	[335]	8	hSpCas9	negative selection	10469595
18609549	18609572	X	+	28162770	SKM1	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.5190352198130613	[59]	[151]	5	hSpCas9	negative selection	10469596
18613154	18613177	X	-	28162770	SKM1	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.5405683813627027	[104]	[269]	5	hSpCas9	negative selection	10469597
18625192	18625215	X	+	28162770	SKM1	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	-0.2480103151218524	[87]	[130]	-2	hSpCas9	negative selection	10469598
18628526	18628549	X	+	28162770	SKM1	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.2814333166593026	[21]	[31]	-2	hSpCas9	negative selection	10469599
18564473	18564496	X	+	28162770	SKM1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.7048578481355823	[227]	[656]	6	hSpCas9	negative selection	10469600
18584317	18584340	X	-	28162770	SKM1	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.4146045825341431	[100]	[237]	4	hSpCas9	negative selection	10469601
18587997	18588020	X	+	28162770	SKM1	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.21547300739665726	[75]	[155]	2	hSpCas9	negative selection	10638958
18603957	18603980	X	+	28162770	SKM1	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.30280475771427506	[82]	[180]	3	hSpCas9	negative selection	10638959
18604371	18604394	X	+	28162770	SKM1	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	-0.2914869813232257	[17]	[25]	-2	hSpCas9	negative selection	10638960
18604804	18604827	X	+	28162770	SKM1	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	1.0625210845580586	[90]	[335]	8	hSpCas9	negative selection	10638961
18609549	18609572	X	+	28162770	SKM1	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.5190352198130613	[59]	[151]	5	hSpCas9	negative selection	10638962
18613154	18613177	X	-	28162770	SKM1	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.5405683813627027	[104]	[269]	5	hSpCas9	negative selection	10638963
18625192	18625215	X	+	28162770	SKM1	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	-0.2480103151218524	[87]	[130]	-2	hSpCas9	negative selection	10638964
18628526	18628549	X	+	28162770	SKM1	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.2814333166593026	[21]	[31]	-2	hSpCas9	negative selection	10638965
18564473	18564496	X	+	28162770	SKM1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.7048578481355823	[227]	[656]	6	hSpCas9	negative selection	10638966
18584317	18584340	X	-	28162770	SKM1	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.4146045825341431	[100]	[237]	4	hSpCas9	negative selection	10638967
18587997	18588020	X	+	28162770	PL21	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	-0.6236097458189527	[353]	[99]	-4	hSpCas9	negative selection	10808324
18603957	18603980	X	+	28162770	PL21	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	-0.08576925759706022	[355]	[145]	0	hSpCas9	negative selection	10808325
18604371	18604394	X	+	28162770	PL21	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	1.0015939351072398	[69]	[60]	8	hSpCas9	negative selection	10808326
18604804	18604827	X	+	28162770	PL21	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.7867424735917318	[292]	[219]	6	hSpCas9	negative selection	10808327
18609549	18609572	X	+	28162770	PL21	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.45647936774910564	[143]	[85]	4	hSpCas9	negative selection	10808328
18613154	18613177	X	-	28162770	PL21	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.09409797707899559	[380]	[176]	0	hSpCas9	negative selection	10808329
18625192	18625215	X	+	28162770	PL21	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.509243669019099	[225]	[139]	4	hSpCas9	negative selection	10808330
18628526	18628549	X	+	28162770	PL21	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.11180439182542012	[71]	[28]	-1	hSpCas9	negative selection	10808331
18564473	18564496	X	+	28162770	PL21	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.008029760088914761	[769]	[336]	0	hSpCas9	negative selection	10808332
18584317	18584340	X	-	28162770	PL21	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.5307267919688525	[298]	[187]	4	hSpCas9	negative selection	10808333
18587997	18588020	X	+	28162770	P31FUJ	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.4573185262921602	[312]	[504]	5	hSpCas9	negative selection	10977690
18603957	18603980	X	+	28162770	P31FUJ	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.10319300260853381	[346]	[437]	1	hSpCas9	negative selection	10977691
18604371	18604394	X	+	28162770	P31FUJ	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	1.0302322014194154	[49]	[119]	9	hSpCas9	negative selection	10977692
18604804	18604827	X	+	28162770	P31FUJ	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.6689337792707555	[242]	[453]	7	hSpCas9	negative selection	10977693
18609549	18609572	X	+	28162770	P31FUJ	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.2255627265285658	[122]	[168]	2	hSpCas9	negative selection	10977694
18613154	18613177	X	-	28162770	P31FUJ	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.36057253612297757	[341]	[515]	4	hSpCas9	negative selection	10977695
18625192	18625215	X	+	28162770	P31FUJ	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	1.087275094785042	[311]	[778]	9	hSpCas9	negative selection	10977696
18628526	18628549	X	+	28162770	P31FUJ	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.02844370590819234	[137]	[158]	0	hSpCas9	negative selection	10977697
18564473	18564496	X	+	28162770	P31FUJ	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.4827539994928407	[963]	[1582]	5	hSpCas9	negative selection	10977698
18584317	18584340	X	-	28162770	P31FUJ	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.5311725100848067	[380]	[646]	6	hSpCas9	negative selection	10977699
18587997	18588020	X	+	28162770	OCIAML5	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.9013760688443135	[147]	[498]	7	hSpCas9	negative selection	11147056
18603957	18603980	X	+	28162770	OCIAML5	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	-0.08813392909752138	[264]	[449]	0	hSpCas9	negative selection	11147057
18604371	18604394	X	+	28162770	OCIAML5	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.3615289022352919	[46]	[108]	3	hSpCas9	negative selection	11147058
18604804	18604827	X	+	28162770	OCIAML5	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.332851145053788	[233]	[531]	3	hSpCas9	negative selection	11147059
18609549	18609572	X	+	28162770	OCIAML5	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	1.268685588596613	[62]	[273]	9	hSpCas9	negative selection	11147060
18613154	18613177	X	-	28162770	OCIAML5	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	-0.053053628597173996	[222]	[387]	0	hSpCas9	negative selection	11147061
18625192	18625215	X	+	28162770	OCIAML5	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.6081597021811022	[164]	[453]	5	hSpCas9	negative selection	11147062
18628526	18628549	X	+	28162770	OCIAML5	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	1.910434115409347	[41]	[284]	9	hSpCas9	negative selection	11147063
18564473	18564496	X	+	28162770	OCIAML5	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.8172244487064311	[514]	[1637]	7	hSpCas9	negative selection	11147064
18584317	18584340	X	-	28162770	OCIAML5	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.33470194074172954	[245]	[559]	3	hSpCas9	negative selection	11147065
18587997	18588020	X	+	28162770	EOL1	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	1.0217874251067423	[544]	[582]	8	hSpCas9	negative selection	11316422
18603957	18603980	X	+	28162770	EOL1	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.828192707675399	[355]	[332]	7	hSpCas9	negative selection	11316423
18604371	18604394	X	+	28162770	EOL1	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	1.0892925339071668	[123]	[138]	8	hSpCas9	negative selection	11316424
18604804	18604827	X	+	28162770	EOL1	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.508553895033672	[502]	[376]	4	hSpCas9	negative selection	11316425
18609549	18609572	X	+	28162770	EOL1	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	-0.3815553561551454	[271]	[109]	-3	hSpCas9	negative selection	11316426
18613154	18613177	X	-	28162770	EOL1	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.7880270101480363	[586]	[533]	7	hSpCas9	negative selection	11316427
18625192	18625215	X	+	28162770	EOL1	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.7783771234276395	[383]	[346]	7	hSpCas9	negative selection	11316428
18628526	18628549	X	+	28162770	EOL1	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.03481024393211962	[104]	[53]	0	hSpCas9	negative selection	11316429
18564473	18564496	X	+	28162770	EOL1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.3453908925305842	[991]	[663]	3	hSpCas9	negative selection	11316430
18584317	18584340	X	-	28162770	EOL1	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.3904576006479274	[403]	[278]	3	hSpCas9	negative selection	11316431
18587997	18588020	X	+	28162770	MOLM13	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.3092644125346863	[460]	[412]	2	hSpCas9	negative selection	11485788
18603957	18603980	X	+	28162770	MOLM13	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.9175730236303139	[431]	[589]	7	hSpCas9	negative selection	11485789
18604371	18604394	X	+	28162770	MOLM13	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.6475954037794768	[97]	[110]	5	hSpCas9	negative selection	11485790
18604804	18604827	X	+	28162770	MOLM13	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	1.4411720431687995	[435]	[855]	9	hSpCas9	negative selection	11485791
18609549	18609572	X	+	28162770	MOLM13	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.4617891820081609	[236]	[235]	3	hSpCas9	negative selection	11485792
18613154	18613177	X	-	28162770	MOLM13	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	1.1894629252938032	[489]	[807]	8	hSpCas9	negative selection	11485793
18625192	18625215	X	+	28162770	MOLM13	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.02965103882386888	[396]	[292]	0	hSpCas9	negative selection	11485794
18628526	18628549	X	+	28162770	MOLM13	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	0.005783628608956093	[134]	[97]	0	hSpCas9	negative selection	11485795
18564473	18564496	X	+	28162770	MOLM13	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.1663880020747901	[1086]	[881]	1	hSpCas9	negative selection	11485796
18584317	18584340	X	-	28162770	MOLM13	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	1.0289218654669972	[384]	[567]	7	hSpCas9	negative selection	11485797
18587997	18588020	X	+	28162770	HEL	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	1.1785417201021906	[397]	[576]	9	hSpCas9	negative selection	11655154
18603957	18603980	X	+	28162770	HEL	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.1348317579442303	[400]	[281]	1	hSpCas9	negative selection	11655155
18604371	18604394	X	+	28162770	HEL	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	-0.42630281242929446	[106]	[50]	-3	hSpCas9	negative selection	11655156
18604804	18604827	X	+	28162770	HEL	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	1.0506694447849407	[406]	[539]	8	hSpCas9	negative selection	11655157
18609549	18609572	X	+	28162770	HEL	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.5067611624813823	[188]	[171]	4	hSpCas9	negative selection	11655158
18613154	18613177	X	-	28162770	HEL	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.40408135630112463	[445]	[377]	3	hSpCas9	negative selection	11655159
18625192	18625215	X	+	28162770	HEL	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.1355684918853518	[360]	[253]	1	hSpCas9	negative selection	11655160
18628526	18628549	X	+	28162770	HEL	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	0.7965441680793924	[79]	[88]	7	hSpCas9	negative selection	11655161
18564473	18564496	X	+	28162770	HEL	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.4897397460815829	[804]	[723]	4	hSpCas9	negative selection	11655162
18584317	18584340	X	-	28162770	HEL	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.030881104216140542	[378]	[247]	0	hSpCas9	negative selection	11655163
18587997	18588020	X	+	28162770	MV411	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	1.462866024369459	[266]	[619]	9	hSpCas9	negative selection	11824520
18603957	18603980	X	+	28162770	MV411	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.44694354277480564	[235]	[270]	4	hSpCas9	negative selection	11824521
18604371	18604394	X	+	28162770	MV411	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.41736255222508745	[55]	[62]	4	hSpCas9	negative selection	11824522
18604804	18604827	X	+	28162770	MV411	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.22625222089214736	[342]	[337]	2	hSpCas9	negative selection	11824523
18609549	18609572	X	+	28162770	MV411	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	-0.09263789081484647	[199]	[157]	0	hSpCas9	negative selection	11824524
18613154	18613177	X	-	28162770	MV411	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.3374871554251988	[294]	[313]	3	hSpCas9	negative selection	11824525
18625192	18625215	X	+	28162770	MV411	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.3549219774491806	[180]	[194]	3	hSpCas9	negative selection	11824526
18628526	18628549	X	+	28162770	MV411	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	1.1608498657866846	[102]	[193]	8	hSpCas9	negative selection	11824527
18564473	18564496	X	+	28162770	MV411	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.7135355389857845	[686]	[948]	6	hSpCas9	negative selection	11824528
18584317	18584340	X	-	28162770	MV411	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.4538884282502018	[311]	[359]	4	hSpCas9	negative selection	11824529
18587997	18588020	X	+	28162770	MONOMAC1	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	-0.5437683329474885	[219]	[172]	-4	hSpCas9	negative selection	11993886
18603957	18603980	X	+	28162770	MONOMAC1	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	0.4771929917586897	[234]	[374]	5	hSpCas9	negative selection	11993887
18604371	18604394	X	+	28162770	MONOMAC1	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	-0.07150596497569484	[43]	[47]	0	hSpCas9	negative selection	11993888
18604804	18604827	X	+	28162770	MONOMAC1	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.16229121963300241	[197]	[253]	1	hSpCas9	negative selection	11993889
18609549	18609572	X	+	28162770	MONOMAC1	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.16692646762502086	[114]	[147]	1	hSpCas9	negative selection	11993890
18613154	18613177	X	-	28162770	MONOMAC1	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	-0.49615505903882995	[250]	[203]	-4	hSpCas9	negative selection	11993891
18625192	18625215	X	+	28162770	MONOMAC1	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.3600914454648769	[156]	[230]	3	hSpCas9	negative selection	11993892
18628526	18628549	X	+	28162770	MONOMAC1	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	0.8253309659689005	[31]	[64]	7	hSpCas9	negative selection	11993893
18564473	18564496	X	+	28162770	MONOMAC1	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.49406173834932376	[440]	[711]	5	hSpCas9	negative selection	11993894
18584317	18584340	X	-	28162770	MONOMAC1	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.6664611530355841	[215]	[392]	6	hSpCas9	negative selection	11993895
18587997	18588020	X	+	28162770	OCIAML2	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	1.0891620997440892	[52]	[624]	9	hSpCas9	negative selection	12163252
18603957	18603980	X	+	28162770	OCIAML2	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	-0.37806370650608867	[82]	[353]	-3	hSpCas9	negative selection	12163253
18604371	18604394	X	+	28162770	OCIAML2	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.06280237483891293	[18]	[109]	0	hSpCas9	negative selection	12163254
18604804	18604827	X	+	28162770	OCIAML2	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.6262317140104278	[62]	[538]	6	hSpCas9	negative selection	12163255
18609549	18609572	X	+	28162770	OCIAML2	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	0.5159496589955173	[26]	[213]	5	hSpCas9	negative selection	12163256
18613154	18613177	X	-	28162770	OCIAML2	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	1.0425969218800804	[66]	[764]	8	hSpCas9	negative selection	12163257
18625192	18625215	X	+	28162770	OCIAML2	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	1.2392909459098163	[34]	[457]	9	hSpCas9	negative selection	12163258
18628526	18628549	X	+	28162770	OCIAML2	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-1.055592325963317	[14]	[39]	-6	hSpCas9	negative selection	12163259
18564473	18564496	X	+	28162770	OCIAML2	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.6268217130129818	[126]	[1086]	6	hSpCas9	negative selection	12163260
18584317	18584340	X	-	28162770	OCIAML2	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.5053532936393033	[52]	[416]	5	hSpCas9	negative selection	12163261
18587997	18588020	X	+	28162770	OCIAML3	viability	ATTCTTGGGGAGCTTAGCGATGG	CDKL5	ENSG00000008086	0.48763082870019425	[72]	[308]	4	hSpCas9	negative selection	12332618
18603957	18603980	X	+	28162770	OCIAML3	viability	GACATCCAGAACCTGAGTGTAGG	CDKL5	ENSG00000008086	-0.11952167596457663	[103]	[288]	-1	hSpCas9	negative selection	12332619
18604371	18604394	X	+	28162770	OCIAML3	viability	AGGACCAAGGCCAAAAGCCATGG	CDKL5	ENSG00000008086	0.7733634253243662	[24]	[128]	7	hSpCas9	negative selection	12332620
18604804	18604827	X	+	28162770	OCIAML3	viability	GAAGCTTGAGCATAGGGCAAGGG	CDKL5	ENSG00000008086	0.7990327566821495	[94]	[498]	7	hSpCas9	negative selection	12332621
18609549	18609572	X	+	28162770	OCIAML3	viability	AGAGTTGGTAGCTTTTACAGAGG	CDKL5	ENSG00000008086	-0.38964914181797694	[45]	[105]	-3	hSpCas9	negative selection	12332622
18613154	18613177	X	-	28162770	OCIAML3	viability	GAATTGTCTGGACGTGGAGATGG	CDKL5	ENSG00000008086	0.28195109573246424	[87]	[322]	2	hSpCas9	negative selection	12332623
18625192	18625215	X	+	28162770	OCIAML3	viability	CAAGCAGCAGACCAAAGGAGTGG	CDKL5	ENSG00000008086	0.5916355948650796	[70]	[322]	5	hSpCas9	negative selection	12332624
18628526	18628549	X	+	28162770	OCIAML3	viability	CGGGAGCAGCAACATCCGGCAGG	CDKL5	ENSG00000008086	-0.2720795454368008	[21]	[54]	-2	hSpCas9	negative selection	12332625
18564473	18564496	X	+	28162770	OCIAML3	viability	GCAGGAAACACATGAAATTGTGG	CDKL5	ENSG00000008086	0.3152268957526547	[204]	[769]	3	hSpCas9	negative selection	12332626
18584317	18584340	X	-	28162770	OCIAML3	viability	TGGGGACCGATACCATCTGGTGG	CDKL5	ENSG00000008086	0.5228561173667353	[79]	[346]	5	hSpCas9	negative selection	12332627