Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1033
• Symbol:CDKN3
• Description:cyclin dependent kinase inhibitor 3

DataSource: http://genomecrispr.dkfz.de/#!/results/CDKN3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
54411480	54411503	14	+	26472758	Jiyoye	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.040578237284782714	[204]	[158]	0	hSpCas9	negative selection	29071
54417889	54417912	14	-	26472758	Jiyoye	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.3627812621474198	[32]	[31]	2	hSpCas9	negative selection	29072
54417912	54417935	14	+	26472758	Jiyoye	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	1.4184906947337077	[126]	[255]	8	hSpCas9	negative selection	29073
54411563	54411586	14	-	26472758	Jiyoye	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.9997510663369047	[62]	[94]	6	hSpCas9	negative selection	29074
54397056	54397079	14	+	26472758	Jiyoye	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	0.10232079997745258	[62]	[50]	0	hSpCas9	negative selection	29075
54417930	54417953	14	+	26472758	Jiyoye	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.03646021321232429	[202]	[156]	0	hSpCas9	negative selection	29076
54411609	54411632	14	-	26472758	Jiyoye	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-1.0811110998036089	[100]	[35]	-6	hSpCas9	negative selection	29077
54415895	54415918	14	+	26472758	Jiyoye	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.2389750605330221	[208]	[185]	1	hSpCas9	negative selection	29078
54415909	54415932	14	+	26472758	Jiyoye	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	3.101072253780194	[16]	[109]	9	hSpCas9	negative selection	29079
54411515	54411538	14	+	26472758	Jiyoye	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.06203989545718569	[281]	[221]	0	hSpCas9	negative selection	29080
54411480	54411503	14	+	26472758	KBM7	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.18640639284804034	[747,465]	[419,227]	2	hSpCas9	negative selection	220189
54417889	54417912	14	-	26472758	KBM7	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.8825167698710604	[111,194]	[148,126]	8	hSpCas9	negative selection	220190
54417912	54417935	14	+	26472758	KBM7	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	-0.20549238369773504	[1029,592]	[296,346]	-2	hSpCas9	negative selection	220191
54411563	54411586	14	-	26472758	KBM7	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.5199864734654619	[488,366]	[327,247]	5	hSpCas9	negative selection	220192
54397056	54397079	14	+	26472758	KBM7	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	1.0721245913380661	[194,156]	[98,238]	9	hSpCas9	negative selection	220193
54417930	54417953	14	+	26472758	KBM7	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.3612535132869451	[654,509]	[451,256]	4	hSpCas9	negative selection	220194
54411609	54411632	14	-	26472758	KBM7	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.13326628153474412	[383,328]	[158,204]	1	hSpCas9	negative selection	220195
54415895	54415918	14	+	26472758	KBM7	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.4008953709659294	[967,912]	[632,541]	4	hSpCas9	negative selection	220196
54415909	54415932	14	+	26472758	KBM7	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.3685768785260188	[192,342]	[174,161]	4	hSpCas9	negative selection	220197
54411515	54411538	14	+	26472758	KBM7	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.5264751230671665	[1035,737]	[605,581]	6	hSpCas9	negative selection	220198
54411480	54411503	14	+	26472758	Raji	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.4498524087017985	[264]	[83]	4	hSpCas9	negative selection	411307
54417889	54417912	14	-	26472758	Raji	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	-0.012355708900496198	[112]	[25]	0	hSpCas9	negative selection	411308
54417912	54417935	14	+	26472758	Raji	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.5137821163785705	[334]	[110]	5	hSpCas9	negative selection	411309
54411563	54411586	14	-	26472758	Raji	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.7178167236108739	[130]	[49]	6	hSpCas9	negative selection	411310
54397056	54397079	14	+	26472758	Raji	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	-2.2054994199107556	[158]	[7]	-8	hSpCas9	negative selection	411311
54417930	54417953	14	+	26472758	Raji	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	1.3498076615321073	[234]	[138]	9	hSpCas9	negative selection	411312
54411609	54411632	14	-	26472758	Raji	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.5995694897261672	[221]	[33]	-5	hSpCas9	negative selection	411313
54415895	54415918	14	+	26472758	Raji	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	1.0011841315416743	[309]	[143]	8	hSpCas9	negative selection	411314
54415909	54415932	14	+	26472758	Raji	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.5756630559294227	[132]	[45]	5	hSpCas9	negative selection	411315
54411515	54411538	14	+	26472758	Raji	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.5865513720721589	[593]	[206]	5	hSpCas9	negative selection	411316
54411480	54411503	14	+	26472758	K562	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	1.1864839585823055	[469]	[902]	8	hSpCas9	negative selection	602425
54417889	54417912	14	-	26472758	K562	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.8207680980828951	[111]	[166]	6	hSpCas9	negative selection	602426
54417912	54417935	14	+	26472758	K562	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	1.167388241813521	[576]	[1093]	8	hSpCas9	negative selection	602427
54411563	54411586	14	-	26472758	K562	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.2859978314178463	[341]	[351]	2	hSpCas9	negative selection	602428
54397056	54397079	14	+	26472758	K562	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	-0.42627364708059345	[155]	[97]	-3	hSpCas9	negative selection	602429
54417930	54417953	14	+	26472758	K562	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.7184819644215306	[436]	[606]	6	hSpCas9	negative selection	602430
54411609	54411632	14	-	26472758	K562	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.8642350605235418	[258]	[397]	7	hSpCas9	negative selection	602431
54415895	54415918	14	+	26472758	K562	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.8626873150047816	[627]	[963]	7	hSpCas9	negative selection	602432
54415909	54415932	14	+	26472758	K562	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	-0.012146182837789232	[355]	[297]	0	hSpCas9	negative selection	602433
54411515	54411538	14	+	26472758	K562	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.7817282527961871	[830]	[1205]	6	hSpCas9	negative selection	602434
54401561	54401584	14	+	26627737	DLD1	viability	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-0.7039277454827269	[88]	[7,45,0]	-6	hSpCas9	negative selection	788760
54411563	54411586	14	-	26627737	DLD1	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.9060157617654117	[93]	[33,17,103]	8	hSpCas9	negative selection	788761
54411600	54411623	14	+	26627737	DLD1	viability	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.03431451412183263	[456]	[89,81,229]	0	hSpCas9	negative selection	788762
54417870	54417893	14	-	26627737	DLD1	viability	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.256078748477337	[1047]	[388,516,288]	2	hSpCas9	negative selection	788763
54401561	54401584	14	+	26627737	GBM cells	viability after 5 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.020904399264296103	[33]	[26,9]	0	hSpCas9	negative selection	871075
54411563	54411586	14	-	26627737	GBM cells	viability after 5 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.3206525023719986	[84]	[32,39]	-5	hSpCas9	negative selection	871076
54411600	54411623	14	+	26627737	GBM cells	viability after 5 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.222299712083395	[272]	[109,140]	-3	hSpCas9	negative selection	871077
54417870	54417893	14	-	26627737	GBM cells	viability after 5 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.13295557465924968	[510]	[288,311]	2	hSpCas9	negative selection	871078
54401561	54401584	14	+	26627737	GBM cells	viability after 13 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.2675102752902099	[33]	[19,23]	3	hSpCas9	negative selection	953390
54411563	54411586	14	-	26627737	GBM cells	viability after 13 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.3022483952732138	[84]	[68,46]	4	hSpCas9	negative selection	953391
54411600	54411623	14	+	26627737	GBM cells	viability after 13 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.36599440071166695	[272]	[120,109]	-4	hSpCas9	negative selection	953392
54417870	54417893	14	-	26627737	GBM cells	viability after 13 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.04078356999644095	[510]	[357,225]	0	hSpCas9	negative selection	953393
54401561	54401584	14	+	26627737	GBM cells	viability after 21 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.5682892933009183	[33]	[29,24]	6	hSpCas9	negative selection	1035705
54411563	54411586	14	-	26627737	GBM cells	viability after 21 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.27323733232492686	[84]	[44,31]	-3	hSpCas9	negative selection	1035706
54411600	54411623	14	+	26627737	GBM cells	viability after 21 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.034559744042270496	[272]	[153,149]	0	hSpCas9	negative selection	1035707
54417870	54417893	14	-	26627737	GBM cells	viability after 21 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.2190395902359188	[510]	[319,325]	2	hSpCas9	negative selection	1035708
54401561	54401584	14	+	26627737	RPE1	viability after 9 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	1.3981998747375328	[74]	[67,53]	7	hSpCas9	negative selection	1118020
54411563	54411586	14	-	26627737	RPE1	viability after 9 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.6324658771697012	[188]	[28,49]	-4	hSpCas9	negative selection	1118021
54411600	54411623	14	+	26627737	RPE1	viability after 9 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.7220754695723224	[619]	[224,442]	5	hSpCas9	negative selection	1118022
54417870	54417893	14	-	26627737	RPE1	viability after 9 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.6873652008359916	[1561]	[652,960]	4	hSpCas9	negative selection	1118023
54401561	54401584	14	+	26627737	RPE1	viability after 12 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	1.5932921397334798	[74]	[70,49]	8	hSpCas9	negative selection	1200335
54411563	54411586	14	-	26627737	RPE1	viability after 12 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.15295320209177632	[188]	[37,75]	1	hSpCas9	negative selection	1200336
54411600	54411623	14	+	26627737	RPE1	viability after 12 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.21585719336692605	[619]	[208,176]	1	hSpCas9	negative selection	1200337
54417870	54417893	14	-	26627737	RPE1	viability after 12 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.6968084676942234	[1561]	[738,617]	4	hSpCas9	negative selection	1200338
54401561	54401584	14	+	26627737	RPE1	viability after 15 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.587923481442366	[74]	[9,52]	3	hSpCas9	negative selection	1282650
54411563	54411586	14	-	26627737	RPE1	viability after 15 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.5332472882943593	[188]	[11,60]	-3	hSpCas9	negative selection	1282651
54411600	54411623	14	+	26627737	RPE1	viability after 15 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.32908941927082763	[619]	[145,291]	2	hSpCas9	negative selection	1282652
54417870	54417893	14	-	26627737	RPE1	viability after 15 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.7872407131893007	[1561]	[703,818]	5	hSpCas9	negative selection	1282653
54401561	54401584	14	+	26627737	RPE1	viability after 18 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.46380229961549935	[74]	[39,14]	3	hSpCas9	negative selection	1364965
54411563	54411586	14	-	26627737	RPE1	viability after 18 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.6815763017399692	[188]	[25,37]	-4	hSpCas9	negative selection	1364966
54411600	54411623	14	+	26627737	RPE1	viability after 18 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.8882338952904882	[619]	[256,365]	5	hSpCas9	negative selection	1364967
54417870	54417893	14	-	26627737	RPE1	viability after 18 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	1.055042404430056	[1561]	[929,817]	6	hSpCas9	negative selection	1364968
54401561	54401584	14	+	26627737	HeLa	viability after 8 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-0.3086478282067695	[99]	[55,18,34]	-3	hSpCas9	negative selection	1447280
54411563	54411586	14	-	26627737	HeLa	viability after 8 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.3864898512257182	[85]	[65,27,55]	3	hSpCas9	negative selection	1447281
54411600	54411623	14	+	26627737	HeLa	viability after 8 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.6417704841587277	[164]	[197,59,97]	5	hSpCas9	negative selection	1447282
54417870	54417893	14	-	26627737	HeLa	viability after 8 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.5046467136644579	[852]	[679,516,423]	4	hSpCas9	negative selection	1447283
54401561	54401584	14	+	26627737	HeLa	viability after 12 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-0.6164875321473837	[99]	[2,37,37]	-5	hSpCas9	negative selection	1529595
54411563	54411586	14	-	26627737	HeLa	viability after 12 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.7259385380672585	[85]	[0,57,0]	-6	hSpCas9	negative selection	1529596
54411600	54411623	14	+	26627737	HeLa	viability after 12 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	1.112433051930737	[164]	[117,160,160]	7	hSpCas9	negative selection	1529597
54417870	54417893	14	-	26627737	HeLa	viability after 12 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.5567661354088607	[852]	[654,457,452]	4	hSpCas9	negative selection	1529598
54401561	54401584	14	+	26627737	HeLa	viability after 15 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-0.8240611018344759	[99]	[20,0,48]	-6	hSpCas9	negative selection	1611910
54411563	54411586	14	-	26627737	HeLa	viability after 15 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.7362591051381706	[85]	[120,32,16]	6	hSpCas9	negative selection	1611911
54411600	54411623	14	+	26627737	HeLa	viability after 15 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.5602632604300156	[164]	[61,131,103]	4	hSpCas9	negative selection	1611912
54417870	54417893	14	-	26627737	HeLa	viability after 15 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.3774070665185387	[852]	[386,480,488]	3	hSpCas9	negative selection	1611913
54401561	54401584	14	+	26627737	HeLa	viability after 18 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-0.8884610411241916	[99]	[11,0,48]	-7	hSpCas9	negative selection	1694225
54411563	54411586	14	-	26627737	HeLa	viability after 18 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.6995924212393749	[85]	[80,23,16]	5	hSpCas9	negative selection	1694226
54411600	54411623	14	+	26627737	HeLa	viability after 18 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.5807877574621626	[164]	[38,115,103]	5	hSpCas9	negative selection	1694227
54417870	54417893	14	-	26627737	HeLa	viability after 18 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.33284409285574346	[852]	[233,396,488]	2	hSpCas9	negative selection	1694228
54401561	54401584	14	+	26627737	HCT116	viability after 6 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-1.6155438116802556	[359]	[2,26]	-7	hSpCas9	negative selection	1776540
54411563	54411586	14	-	26627737	HCT116	viability after 6 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.9630908384774703	[131]	[9,10]	-5	hSpCas9	negative selection	1776541
54411600	54411623	14	+	26627737	HCT116	viability after 6 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-1.6694276510322519	[1015]	[104,19]	-7	hSpCas9	negative selection	1776542
54417870	54417893	14	-	26627737	HCT116	viability after 6 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	1.0314515779464115	[1654]	[652,464]	5	hSpCas9	negative selection	1776543
54401561	54401584	14	+	26627737	HCT116	viability after 8 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.6836999495807139	[44]	[56,39,22]	6	hSpCas9	negative selection	1858855
54411563	54411586	14	-	26627737	HCT116	viability after 8 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.10202343631547306	[100]	[70,40,43]	-1	hSpCas9	negative selection	1858856
54411600	54411623	14	+	26627737	HCT116	viability after 8 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.2212648880973922	[211]	[114,94,90]	-3	hSpCas9	negative selection	1858857
54417870	54417893	14	-	26627737	HCT116	viability after 8 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.37206430987331696	[508]	[421,385,282]	4	hSpCas9	negative selection	1858858
54401561	54401584	14	+	26627737	HCT116	viability after 9 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-2.6272267837973877	[359]	[14,15]	-9	hSpCas9	negative selection	1941170
54411563	54411586	14	-	26627737	HCT116	viability after 9 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.36824749817142854	[131]	[97,3]	2	hSpCas9	negative selection	1941171
54411600	54411623	14	+	26627737	HCT116	viability after 9 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-1.1565842777613264	[1015]	[157,92]	-7	hSpCas9	negative selection	1941172
54417870	54417893	14	-	26627737	HCT116	viability after 9 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.18792538832095107	[1654]	[532,479]	1	hSpCas9	negative selection	1941173
54401561	54401584	14	+	26627737	HCT116	viability after 12 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.5205007859543835	[44]	[27,21,51]	5	hSpCas9	negative selection	2023485
54411563	54411586	14	-	26627737	HCT116	viability after 12 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.7380109353034519	[100]	[39,41,12]	-7	hSpCas9	negative selection	2023486
54411600	54411623	14	+	26627737	HCT116	viability after 12 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.3131841697096832	[211]	[127,62,73]	-3	hSpCas9	negative selection	2023487
54417870	54417893	14	-	26627737	HCT116	viability after 12 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.7472379903706259	[508]	[502,354,481]	6	hSpCas9	negative selection	2023488
54401561	54401584	14	+	26627737	HCT116	viability after 15 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.1890505667342457	[44]	[48,31,9]	2	hSpCas9	negative selection	2105800
54411563	54411586	14	-	26627737	HCT116	viability after 15 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.18998375804797818	[100]	[102,34,64]	2	hSpCas9	negative selection	2105801
54411600	54411623	14	+	26627737	HCT116	viability after 15 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.2707383773310912	[211]	[131,28,144]	-3	hSpCas9	negative selection	2105802
54417870	54417893	14	-	26627737	HCT116	viability after 15 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.4461739791808965	[508]	[497,317,390]	4	hSpCas9	negative selection	2105803
54401561	54401584	14	+	26627737	HCT116	viability after 18 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.39100763760934765	[44]	[48,7,29]	3	hSpCas9	negative selection	2188115
54411563	54411586	14	-	26627737	HCT116	viability after 18 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.3768289704971455	[100]	[97,50,40]	3	hSpCas9	negative selection	2188116
54411600	54411623	14	+	26627737	HCT116	viability after 18 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.22333918239455353	[211]	[96,52,116]	-2	hSpCas9	negative selection	2188117
54417870	54417893	14	-	26627737	HCT116	viability after 18 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.6257342513176396	[508]	[547,259,336]	5	hSpCas9	negative selection	2188118
54399894	54399917	14	-	24336569	HL60	viability	TCACTTGTTTGTATTGAACTGGG	CDKN3	ENSG00000100526	0.4328248253196567	[1268]	[3624]	4	hSpCas9	negative selection	2256909
54411480	54411503	14	+	24336569	HL60	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.9718853239640374	[510]	[2120]	7	hSpCas9	negative selection	2256910
54411548	54411571	14	+	24336569	HL60	viability	ATATAGAGTCCCAAACCTTCTGG	CDKN3	ENSG00000100526	-0.9055552870375817	[400]	[452]	-7	hSpCas9	negative selection	2256911
54411557	54411580	14	-	24336569	HL60	viability	GGTAGAGATCCAGAAGGTTTGGG	CDKN3	ENSG00000100526	1.2307565300867798	[506]	[2517]	8	hSpCas9	negative selection	2256912
54411563	54411586	14	-	24336569	HL60	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.15031093319839675	[415]	[976]	1	hSpCas9	negative selection	2256913
54411578	54411601	14	-	24336569	HL60	viability	GGGTGATAATTCCACATTGCTGG	CDKN3	ENSG00000100526	-0.5284444924104944	[410]	[602]	-5	hSpCas9	negative selection	2256914
54411598	54411621	14	-	24336569	HL60	viability	ATCTGCGATTGGATGATGATGGG	CDKN3	ENSG00000100526	-0.08307156045078201	[897]	[1793]	0	hSpCas9	negative selection	2256915
54411603	54411626	14	+	24336569	HL60	viability	CATCATCCAATCGCAGATGGAGG	CDKN3	ENSG00000100526	0.2421602849193646	[679]	[1701]	2	hSpCas9	negative selection	2256916
54411609	54411632	14	-	24336569	HL60	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.6796139496541173	[266]	[904]	6	hSpCas9	negative selection	2256917
54411630	54411653	14	-	24336569	HL60	viability	TCACAGCAGCTGGCTATGTCAGG	CDKN3	ENSG00000100526	-0.45388859784618985	[744]	[1150]	-4	hSpCas9	negative selection	2256918
54399894	54399917	14	-	24336569	KBM7	viability	TCACTTGTTTGTATTGAACTGGG	CDKN3	ENSG00000100526	0.12385316529216883	[1106]	[3289]	1	hSpCas9	negative selection	2324086
54411480	54411503	14	+	24336569	KBM7	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	-0.5411671861299869	[803]	[1506]	-4	hSpCas9	negative selection	2324087
54411548	54411571	14	+	24336569	KBM7	viability	ATATAGAGTCCCAAACCTTCTGG	CDKN3	ENSG00000100526	1.105895912003553	[192]	[1132]	8	hSpCas9	negative selection	2324088
54411557	54411580	14	-	24336569	KBM7	viability	GGTAGAGATCCAGAAGGTTTGGG	CDKN3	ENSG00000100526	0.560366637971672	[678]	[2730]	5	hSpCas9	negative selection	2324089
54411563	54411586	14	-	24336569	KBM7	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	1.6103982047375314	[188]	[1573]	9	hSpCas9	negative selection	2324090
54411578	54411601	14	-	24336569	KBM7	viability	GGGTGATAATTCCACATTGCTGG	CDKN3	ENSG00000100526	-1.2877078597704932	[383]	[428]	-7	hSpCas9	negative selection	2324091
54411598	54411621	14	-	24336569	KBM7	viability	ATCTGCGATTGGATGATGATGGG	CDKN3	ENSG00000100526	0.047126284634891435	[785]	[2214]	0	hSpCas9	negative selection	2324092
54411603	54411626	14	+	24336569	KBM7	viability	CATCATCCAATCGCAGATGGAGG	CDKN3	ENSG00000100526	0.6864687685648334	[759]	[3335]	6	hSpCas9	negative selection	2324093
54411609	54411632	14	-	24336569	KBM7	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.08917421112965385	[354]	[1029]	0	hSpCas9	negative selection	2324094
54411630	54411653	14	-	24336569	KBM7	viability	TCACAGCAGCTGGCTATGTCAGG	CDKN3	ENSG00000100526	1.1520843535187026	[178]	[1084]	8	hSpCas9	negative selection	2324095
54396831	54396854	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGTCTTTCAAAGGTCTTCTAGG	CDKN3	ENSG00000100526	2.79392108437626	[114,196]	[20,475]	8	dCas9-VP64	positive selection	2398864
54396831	54396854	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGTCTTTCAAAGGTCTTCTAGG	CDKN3	ENSG00000100526	0.2660865660959578	[100,286]	[107,44]	2	dCas9-VP64	positive selection	2494119
54408769	54408792	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.11385199650510607	[3,3]	[4,1]	2	hSpCas9	positive selection	2978293
54411563	54411586	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.46204163216635	[4,4]	[4,6]	8	hSpCas9	positive selection	2978294
54411481	54411504	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.1172726319524636	[3,3]	[2,3]	2	hSpCas9	positive selection	2978295
54411609	54411632	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.32029513860578784	[4,4]	[6,4]	6	hSpCas9	positive selection	2978296
54408769	54408792	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.051143592122715346	[3,3]	[2,1]	0	hSpCas9	positive selection	3046151
54411563	54411586	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.3566950891877495	[4,4]	[4,3]	6	hSpCas9	positive selection	3046152
54411481	54411504	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	-0.44338205141018866	[3,3]	[1,0]	-6	hSpCas9	positive selection	3046153
54411609	54411632	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.8037699861411505	[4,4]	[4,7]	9	hSpCas9	positive selection	3046154
54417930	54417953		+	24336571	A375	resistance to PLX after 7 days	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.24652817527891713	[23,20]	[19,17]	-7	hSpCas9	positive selection	3104727
54399895	54399918		-	24336571	A375	resistance to PLX after 7 days	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.35032573640915554	[10,8]	[6,7]	-8	hSpCas9	positive selection	3104729
54401540	54401563		+	24336571	A375	resistance to PLX after 7 days	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.44466609430569	[10,12]	[16,15]	9	hSpCas9	positive selection	3104730
54417899	54417922		-	24336571	A375	resistance to PLX after 7 days	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.1685472054581454	[35,34]	[38,39]	5	hSpCas9	positive selection	3104731
54417930	54417953		+	24336571	A375	resistance to PLX after 14 days	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-1.1180535662622728	[35,28]	[6,5]	-9	hSpCas9	positive selection	3162520
54399895	54399918		-	24336571	A375	resistance to PLX after 14 days	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.440466316204557	[10,6]	[2,2]	-5	hSpCas9	positive selection	3162522
54401540	54401563		+	24336571	A375	resistance to PLX after 14 days	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.9376746827033702	[13,13]	[9,14]	7	hSpCas9	positive selection	3162523
54417899	54417922		-	24336571	A375	resistance to PLX after 14 days	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	2.376172938335991	[37,46]	[115,91]	9	hSpCas9	positive selection	3162524
54417930	54417953		+	24336571	A375	viability after 7 days	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.05888491390341044	[24]	[23,20]	-1	hSpCas9	negative selection	3220313
54399895	54399918		-	24336571	A375	viability after 7 days	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.3177946581533901	[12]	[10,8]	-4	hSpCas9	negative selection	3220315
54401540	54401563		+	24336571	A375	viability after 7 days	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.11510357384798824	[11]	[10,12]	1	hSpCas9	negative selection	3220316
54417899	54417922		-	24336571	A375	viability after 7 days	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.40020035285238076	[27]	[35,34]	6	hSpCas9	negative selection	3220317
54417930	54417953		+	24336571	A375	viability after 14 days	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.4829733656650096	[24]	[35,28]	6	hSpCas9	negative selection	3278106
54399895	54399918		-	24336571	A375	viability after 14 days	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.4360234495541094	[12]	[10,6]	-5	hSpCas9	negative selection	3278108
54401540	54401563		+	24336571	A375	viability after 14 days	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.36031103842925205	[11]	[13,13]	4	hSpCas9	negative selection	3278109
54417899	54417922		-	24336571	A375	viability after 14 days	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.6858235175677712	[27]	[37,46]	8	hSpCas9	negative selection	3278110
54417899	54417922	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	-0.5578791605787514	[258,190]	[0,0]	-4	hSpCas9	positive selection	3342489
54417930	54417953	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.4193760648375885	[292,320]	[0,1]	-3	hSpCas9	positive selection	3342490
54399895	54399918	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.7904133809289198	[81,94]	[0,0]	4	hSpCas9	positive selection	3342491
54401540	54401563	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	-1.1731263402196963	[344,344]	[0,0]	-7	hSpCas9	positive selection	3361723
54408768	54408791	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3361724
54417929	54417952	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	3.5997950847740343	[264,264]	[20,20]	9	hSpCas9	positive selection	3361725
54408768	54408791	14	+	26780180	HT29	viability (Avana library 4 designs)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	1.56730338543326	[]	[]	6	hSpCas9	negative selection	3414606
54411563	54411586	14	-	26780180	HT29	viability (Avana library 4 designs)	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.159380989801821	[]	[]	0	hSpCas9	negative selection	3414607
54411480	54411503	14	+	26780180	HT29	viability (Avana library 4 designs)	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	1.41483973632276	[]	[]	5	hSpCas9	negative selection	3414608
54411609	54411632	14	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.0964839733186531	[]	[]	0	hSpCas9	negative selection	3414609
54411563	54411586	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.810029522944485	[]	[]	-1	hSpCas9	negative selection	3491206
54411480	54411503	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.436902431126678	[]	[]	0	hSpCas9	negative selection	3491207
54411609	54411632	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	6.56598487699591	[]	[]	9	hSpCas9	negative selection	3491208
54408768	54408791	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-15.2991982695132	[]	[]	-9	hSpCas9	negative selection	3491209
54411604	54411627	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATCATCCAATCGCAGATGGAGGG	CDKN3	ENSG00000100526	4.97819892844242	[]	[]	8	hSpCas9	negative selection	3491210
54408772	54408795	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGTCCAAAAAGATACAGGTAGG	CDKN3	ENSG00000100526	-6.04332057631878	[]	[]	-6	hSpCas9	negative selection	3491211
54411563	54411586	14	-	26780180	A375	viability (Avana lentiGuide)	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.121198859707921	[]	[]	0	hSpCas9	negative selection	3599865
54411480	54411503	14	+	26780180	A375	viability (Avana lentiGuide)	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	-3.61329834138675	[]	[]	-6	hSpCas9	negative selection	3599866
54411609	54411632	14	-	26780180	A375	viability (Avana lentiGuide)	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-3.8289395935152	[]	[]	-6	hSpCas9	negative selection	3599867
54408768	54408791	14	+	26780180	A375	viability (Avana lentiGuide)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	4.38671380072383	[]	[]	4	hSpCas9	negative selection	3599868
54411604	54411627	14	+	26780180	A375	viability (Avana lentiGuide)	ATCATCCAATCGCAGATGGAGGG	CDKN3	ENSG00000100526	-5.11768132837092	[]	[]	-8	hSpCas9	negative selection	3599869
54408772	54408795	14	+	26780180	A375	viability (Avana lentiGuide)	ATGTCCAAAAAGATACAGGTAGG	CDKN3	ENSG00000100526	-0.844149497922175	[]	[]	-1	hSpCas9	negative selection	3599870
54411563	54411586	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.12079453411409125	[7]	[6,5]	-2	hSpCas9	positive selection	3708524
54411480	54411503	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.04740288687091775	[4]	[4,4]	1	hSpCas9	positive selection	3708525
54411609	54411632	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.2974728404725866	[5]	[7,6]	8	hSpCas9	positive selection	3708526
54408768	54408791	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.4982348815260046	[6]	[3,4]	-6	hSpCas9	positive selection	3708527
54411604	54411627	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCATCCAATCGCAGATGGAGGG	CDKN3	ENSG00000100526	0.02830601811727762	[5]	[6,5]	0	hSpCas9	positive selection	3708528
54408772	54408795	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGTCCAAAAAGATACAGGTAGG	CDKN3	ENSG00000100526	-0.6944615278866813	[5]	[4,2]	-7	hSpCas9	positive selection	3708529
54411563	54411586	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.21715305801072343	[6]	[6,6]	5	hSpCas9	positive selection	3817131
54411480	54411503	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.047676630864317525	[5]	[5,2]	1	hSpCas9	positive selection	3817132
54411609	54411632	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.28624997636022587	[6]	[6,7]	7	hSpCas9	positive selection	3817133
54408768	54408791	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.20232358453608262	[5]	[2,4]	-3	hSpCas9	positive selection	3817134
54411604	54411627	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCATCCAATCGCAGATGGAGGG	CDKN3	ENSG00000100526	0.3482721758402591	[4]	[5,4]	8	hSpCas9	positive selection	3817135
54408772	54408795	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGTCCAAAAAGATACAGGTAGG	CDKN3	ENSG00000100526	0.2266436304452685	[5]	[4,5]	6	hSpCas9	positive selection	3817136
54408768	54408791	14	+	26780180	A375	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	1.29511410054204	[]	[]	7	hSpCas9	negative selection	3925313
54417930	54417953	14	+	26780180	A375	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.606923626636435	[]	[]	2	hSpCas9	negative selection	3925314
54399895	54399918	14	-	26780180	A375	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	1.08268473453493	[]	[]	5	hSpCas9	negative selection	3925315
54417929	54417952	14	-	26780180	A375	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	1.67776820763548	[]	[]	9	hSpCas9	negative selection	3925316
54401540	54401563	14	+	26780180	A375	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.862863141485465	[]	[]	3	hSpCas9	negative selection	3925317
54417899	54417922	14	-	26780180	A375	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.607421952771295	[]	[]	2	hSpCas9	negative selection	3925318
54408768	54408791	14	+	26780180	HT29	viability (GeCKOv2 library)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	1.42535591594477	[]	[]	7	hSpCas9	negative selection	4033279
54417930	54417953	14	+	26780180	HT29	viability (GeCKOv2 library)	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.932423194704586	[]	[]	4	hSpCas9	negative selection	4033280
54399895	54399918	14	-	26780180	HT29	viability (GeCKOv2 library)	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.884018249874735	[]	[]	4	hSpCas9	negative selection	4033281
54417929	54417952	14	-	26780180	HT29	viability (GeCKOv2 library)	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	1.78472427647203	[]	[]	8	hSpCas9	negative selection	4033282
54401540	54401563	14	+	26780180	HT29	viability (GeCKOv2 library)	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.252743292184944	[]	[]	0	hSpCas9	negative selection	4033283
54417899	54417922	14	-	26780180	HT29	viability (GeCKOv2 library)	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.131531856162507	[]	[]	0	hSpCas9	negative selection	4033284
54417930	54417953	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.031600970273634316	[4]	[2,2]	0	hSpCas9	positive selection	4126756
54399895	54399918	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.28417060995747223	[3]	[1,1]	-6	hSpCas9	positive selection	4126758
54401540	54401563	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.16609741971657876	[3]	[1,3]	4	hSpCas9	positive selection	4126759
54417899	54417922	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.7446802210261747	[5]	[5,6]	9	hSpCas9	positive selection	4126760
54417930	54417953	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	1.1797452319147064	[4]	[3,4,3,4]	8	hSpCas9	positive selection	4190778
54399895	54399918	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	1.1508998607872174	[1]	[3,0,1,0]	8	hSpCas9	positive selection	4190780
54401540	54401563	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.8194586981749463	[3]	[1,4,1,3]	5	hSpCas9	positive selection	4190781
54417899	54417922	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.32527013336244637	[5]	[5,4,3,0]	2	hSpCas9	positive selection	4190782
54417899	54417922	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.09701392643446685	[3]	[3,2]	2	hSpCas9	positive selection	4262545
54417930	54417953	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.41050768003159377	[3]	[4,3]	8	hSpCas9	positive selection	4262546
54399895	54399918	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.14093929512290715	[2]	[2,0]	-3	hSpCas9	positive selection	4262547
54401540	54401563	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.20562429252773481	[3]	[4,1]	4	hSpCas9	positive selection	4326823
54408768	54408791	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.01119249578516407	[1]	[1,1]	0	hSpCas9	positive selection	4326824
54417929	54417952	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	0.0028644849202493494	[3]	[3,2]	0	hSpCas9	positive selection	4326825
54411481	54411503	14	+	27760321	OCIAML3	viability	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.7582003059321685	[221,183]	[239,302]	8	hSpCas9	negative selection	4388197
54411514	54411536	14	+	27760321	OCIAML3	viability	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	0.9787891466128222	[587,561]	[732,1088]	9	hSpCas9	negative selection	4388198
54411529	54411551	14	-	27760321	OCIAML3	viability	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.06015350027291616	[454,383]	[293,338]	0	hSpCas9	negative selection	4388199
54411568	54411590	14	+	27760321	OCIAML3	viability	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.060830161280036946	[424,401]	[285,404]	0	hSpCas9	negative selection	4388200
54411609	54411631	14	-	27760321	OCIAML3	viability	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.05091953398661786	[652,626]	[468,584]	0	hSpCas9	negative selection	4388201
54411481	54411503	14	+	27760321	OCIAML2	viability	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.14268440306258612	[221,183]	[170,192]	1	hSpCas9	negative selection	4471660
54411514	54411536	14	+	27760321	OCIAML2	viability	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	1.0669554511533919	[587,561]	[949,1009]	9	hSpCas9	negative selection	4471661
54411529	54411551	14	-	27760321	OCIAML2	viability	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	0.23493000551001259	[454,383]	[368,435]	3	hSpCas9	negative selection	4471662
54411568	54411590	14	+	27760321	OCIAML2	viability	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.4519759538158219	[424,401]	[369,573]	6	hSpCas9	negative selection	4471663
54411609	54411631	14	-	27760321	OCIAML2	viability	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.3195603266805701	[652,626]	[603,703]	4	hSpCas9	negative selection	4471664
54411481	54411503	14	+	27760321	MV411	viability	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	-0.6175364446756393	[221,183]	[0,215]	-4	hSpCas9	negative selection	4555123
54411514	54411536	14	+	27760321	MV411	viability	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	1.0380930560412462	[587,561]	[663,954]	7	hSpCas9	negative selection	4555124
54411529	54411551	14	-	27760321	MV411	viability	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	0.6855294860594	[454,383]	[431,460]	5	hSpCas9	negative selection	4555125
54411568	54411590	14	+	27760321	MV411	viability	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.48789200580103653	[424,401]	[446,286]	3	hSpCas9	negative selection	4555126
54411609	54411631	14	-	27760321	MV411	viability	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.656536096620878	[652,626]	[669,661]	5	hSpCas9	negative selection	4555127
54411481	54411503	14	+	27760321	HL60	viability	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	-0.2016924055839493	[221,183]	[161,123]	-2	hSpCas9	negative selection	4638586
54411514	54411536	14	+	27760321	HL60	viability	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	1.1773017363206788	[587,561]	[906,1229]	9	hSpCas9	negative selection	4638587
54411529	54411551	14	-	27760321	HL60	viability	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	0.0400054538837165	[454,383]	[268,437]	0	hSpCas9	negative selection	4638588
54411568	54411590	14	+	27760321	HL60	viability	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.5425951639628837	[424,401]	[508,474]	6	hSpCas9	negative selection	4638589
54411609	54411631	14	-	27760321	HL60	viability	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.019014837944445584	[652,626]	[367,702]	0	hSpCas9	negative selection	4638590
54411481	54411503	14	+	27760321	HT1080	viability	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.05385595448900182	[183,143]	[0,140]	0	hSpCas9	negative selection	4722049
54411514	54411536	14	+	27760321	HT1080	viability	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	0.5827825583626056	[561,438]	[406,179]	3	hSpCas9	negative selection	4722050
54411529	54411551	14	-	27760321	HT1080	viability	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.5428815252678488	[383,299]	[93,92]	-2	hSpCas9	negative selection	4722051
54411568	54411590	14	+	27760321	HT1080	viability	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.7390214213058163	[401,313]	[238,236]	4	hSpCas9	negative selection	4722052
54411609	54411631	14	-	27760321	HT1080	viability	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.6352318720652637	[626,488]	[244,454]	3	hSpCas9	negative selection	4722053
54411481	54411503	14	+	27760321	HT29	viability after 7 days	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.1810712146201191	[183,143]	[269,105,341]	2	hSpCas9	negative selection	4805512
54411514	54411536	14	+	27760321	HT29	viability after 7 days	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	-0.41423058254891726	[561,438]	[428,611,401]	-6	hSpCas9	negative selection	4805513
54411529	54411551	14	-	27760321	HT29	viability after 7 days	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.364200878523602	[383,299]	[308,217,487]	-5	hSpCas9	negative selection	4805514
54411568	54411590	14	+	27760321	HT29	viability after 7 days	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.28570016127423714	[401,313]	[589,482,611]	4	hSpCas9	negative selection	4805515
54411609	54411631	14	-	27760321	HT29	viability after 7 days	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.3038258091317047	[626,488]	[499,583,644]	-4	hSpCas9	negative selection	4805516
54411481	54411503	14	+	27760321	HT29	viability after 25 days	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.2716507383018486	[183,143]	[290,186,192]	3	hSpCas9	negative selection	4888975
54411514	54411536	14	+	27760321	HT29	viability after 25 days	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	-0.04083382841386152	[561,438]	[624,360,690]	0	hSpCas9	negative selection	4888976
54411529	54411551	14	-	27760321	HT29	viability after 25 days	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.4316136382635951	[383,299]	[355,268,233]	-4	hSpCas9	negative selection	4888977
54411568	54411590	14	+	27760321	HT29	viability after 25 days	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.3146374631852719	[401,313]	[475,429,634]	3	hSpCas9	negative selection	4888978
54411609	54411631	14	-	27760321	HT29	viability after 25 days	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.03905448043908033	[626,488]	[550,730,692]	0	hSpCas9	negative selection	4888979
54411481	54411503	14	+	27760321	HT29	viability after 22 days	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.42289596302214916	[183,143]	[254,316,189]	4	hSpCas9	negative selection	4972438
54411514	54411536	14	+	27760321	HT29	viability after 22 days	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	-0.2313825262350135	[561,438]	[508,498,469]	-2	hSpCas9	negative selection	4972439
54411529	54411551	14	-	27760321	HT29	viability after 22 days	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.02580861491183184	[383,299]	[341,371,452]	0	hSpCas9	negative selection	4972440
54411568	54411590	14	+	27760321	HT29	viability after 22 days	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.31146814277758356	[401,313]	[718,332,482]	3	hSpCas9	negative selection	4972441
54411609	54411631	14	-	27760321	HT29	viability after 22 days	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.08242592789197534	[626,488]	[492,880,679]	0	hSpCas9	negative selection	4972442
54411481	54411503	14	+	27760321	HT29	viability after 19 days	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.3477644818477438	[183,143]	[508,121,117]	3	hSpCas9	negative selection	5055901
54411514	54411536	14	+	27760321	HT29	viability after 19 days	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	-0.2810569428586297	[561,438]	[657,287,485]	-3	hSpCas9	negative selection	5055902
54411529	54411551	14	-	27760321	HT29	viability after 19 days	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.18591722921059295	[383,299]	[587,153,315]	-2	hSpCas9	negative selection	5055903
54411568	54411590	14	+	27760321	HT29	viability after 19 days	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.4441188808801974	[401,313]	[474,436,742]	4	hSpCas9	negative selection	5055904
54411609	54411631	14	-	27760321	HT29	viability after 19 days	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.014324330039814037	[626,488]	[690,704,509]	0	hSpCas9	negative selection	5055905
54411481	54411503	14	+	27760321	HT29	viability after 16 days	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	-0.04914637548984491	[183,143]	[147,188,191]	0	hSpCas9	negative selection	5139364
54411514	54411536	14	+	27760321	HT29	viability after 16 days	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	0.22373354357489877	[561,438]	[748,602,619]	2	hSpCas9	negative selection	5139365
54411529	54411551	14	-	27760321	HT29	viability after 16 days	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	0.0630522566285895	[383,299]	[452,407,342]	0	hSpCas9	negative selection	5139366
54411568	54411590	14	+	27760321	HT29	viability after 16 days	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.33036689856391815	[401,313]	[356,539,598]	3	hSpCas9	negative selection	5139367
54411609	54411631	14	-	27760321	HT29	viability after 16 days	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.1305435612257061	[626,488]	[431,708,552]	-1	hSpCas9	negative selection	5139368
54411481	54411503	14	+	27760321	HT29	viability after 13 days	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.5139392762248426	[183,143]	[416,180,219]	6	hSpCas9	negative selection	5222827
54411514	54411536	14	+	27760321	HT29	viability after 13 days	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	-0.25136843099498707	[561,438]	[454,393,606]	-3	hSpCas9	negative selection	5222828
54411529	54411551	14	-	27760321	HT29	viability after 13 days	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.38836238155457004	[383,299]	[251,277,374]	-4	hSpCas9	negative selection	5222829
54411568	54411590	14	+	27760321	HT29	viability after 13 days	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	0.32130863571957075	[401,313]	[492,530,531]	4	hSpCas9	negative selection	5222830
54411609	54411631	14	-	27760321	HT29	viability after 13 days	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.011840503186953288	[626,488]	[537,708,676]	0	hSpCas9	negative selection	5222831
54411481	54411503	14	+	27760321	HT29	viability after 10 days	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.5051446754988121	[183,143]	[368,336,169]	7	hSpCas9	negative selection	5306290
54411514	54411536	14	+	27760321	HT29	viability after 10 days	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	-0.24309214631435186	[561,438]	[635,579,372]	-3	hSpCas9	negative selection	5306291
54411529	54411551	14	-	27760321	HT29	viability after 10 days	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-0.7044614014603181	[383,299]	[289,266,229]	-7	hSpCas9	negative selection	5306292
54411568	54411590	14	+	27760321	HT29	viability after 10 days	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	-0.17158917590937078	[401,313]	[284,695,221]	-2	hSpCas9	negative selection	5306293
54411609	54411631	14	-	27760321	HT29	viability after 10 days	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.44270928019176414	[626,488]	[427,617,494]	-5	hSpCas9	negative selection	5306294
54411481	54411503	14	+	27760321	MOLM13	viability	CAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.7446436505893161	[221,183]	[122,248]	5	hSpCas9	negative selection	5389753
54411514	54411536	14	+	27760321	MOLM13	viability	TATTTGTTTTCTGCACCAGAGG	CDKN3	ENSG00000100526	1.1442153780972877	[587,561]	[992,483]	7	hSpCas9	negative selection	5389754
54411529	54411551	14	-	27760321	MOLM13	viability	TATTTTGACAGTTCCCCTCTGG	CDKN3	ENSG00000100526	-1.2022722658290628	[454,383]	[95,107]	-6	hSpCas9	negative selection	5389755
54411568	54411590	14	+	27760321	MOLM13	viability	TGGATCTCTACCAGCAATGTGG	CDKN3	ENSG00000100526	1.839935206651388	[424,401]	[781,881]	9	hSpCas9	negative selection	5389756
54411609	54411631	14	-	27760321	MOLM13	viability	GAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.6470254329068559	[652,626]	[601,535]	4	hSpCas9	negative selection	5389757
54397037	54397060	14	+	27661255	K562	viability	GCGGCACTGGTCTCGACGTGGGG	CDKN3	ENSG00000100526	0.10096095612794988	[619,733]	[581,574]	3	dCas9-KRAB	negative selection	5470016
54397434	54397457	14	+	27661255	K562	viability	GATACCCCAGCCCCGAAGGGTGG	CDKN3	ENSG00000100526	0.05272699720738838	[572,813]	[631,518]	1	dCas9-KRAB	negative selection	5470017
54397163	54397186	14	-	27661255	K562	viability	GTCGCACTGCTACCAGGCTAGGG	CDKN3	ENSG00000100526	0.2633107401948971	[88,218]	[139,149]	8	dCas9-KRAB	negative selection	5470018
54417899	54417922	14	-	27260156	BXPC3	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.43138303269309874	[723]	[986,995,972,1138]	8	hSpCas9	negative selection	5535005
54417930	54417953	14	+	27260156	BXPC3	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.17906498663596349	[898]	[988,1075,986,1222]	4	hSpCas9	negative selection	5535006
54399895	54399918	14	-	27260156	BXPC3	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.02768193938798491	[269]	[238,250,258,423]	0	hSpCas9	negative selection	5535007
54401540	54401563	14	+	27260156	BXPC3	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.46790091654559995	[469]	[627,660,752,679]	8	hSpCas9	negative selection	5599283
54408768	54408791	14	+	27260156	BXPC3	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.3242307701073901	[176]	[114,108,188,188]	-6	hSpCas9	negative selection	5599284
54417929	54417952	14	-	27260156	BXPC3	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.14591098449509254	[801]	[657,781,633,987]	-3	hSpCas9	negative selection	5599285
54417899	54417922	14	-	27260156	A673	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.2754612699908756	[723]	[1031,1137,948,1085]	6	hSpCas9	negative selection	5656256
54417930	54417953	14	+	27260156	A673	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.20598587026065185	[898]	[1289,1217,1201,1275]	5	hSpCas9	negative selection	5656257
54399895	54399918	14	-	27260156	A673	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.15705387619161293	[269]	[249,271,384,247]	-4	hSpCas9	negative selection	5656258
54401540	54401563	14	+	27260156	A673	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.3856529968796373	[469]	[802,697,680,776]	8	hSpCas9	negative selection	5720534
54408768	54408791	14	+	27260156	A673	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.05762751203569949	[176]	[235,160,220,202]	-1	hSpCas9	negative selection	5720535
54417929	54417952	14	-	27260156	A673	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.33626753542254423	[801]	[864,695,670,835]	-7	hSpCas9	negative selection	5720536
54417899	54417922	14	-	27260156	A375	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.40623327902322437	[723]	[1094,1338,968,1106]	6	hSpCas9	negative selection	5777507
54417930	54417953	14	+	27260156	A375	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.22077565613558248	[898]	[967,1334,1307,1284]	3	hSpCas9	negative selection	5777508
54399895	54399918	14	-	27260156	A375	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.25775777353028784	[269]	[155,308,325,267]	-4	hSpCas9	negative selection	5777509
54401540	54401563	14	+	27260156	A375	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.9549034515209339	[469]	[1200,1138,741,1168]	9	hSpCas9	negative selection	5841785
54408768	54408791	14	+	27260156	A375	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.02722693283064337	[176]	[164,165,225,270]	0	hSpCas9	negative selection	5841786
54417929	54417952	14	-	27260156	A375	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.1388601985457274	[801]	[619,1255,1000,606]	-2	hSpCas9	negative selection	5841787
54417899	54417922	14	-	27260156	COLO741	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.4140113163078263	[723]	[1388,1158,1164]	8	hSpCas9	negative selection	5898758
54417930	54417953	14	+	27260156	COLO741	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.12769029378038543	[898]	[1197,832,1126]	-3	hSpCas9	negative selection	5898759
54399895	54399918	14	-	27260156	COLO741	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.11523867610272098	[269]	[305,304,340]	-2	hSpCas9	negative selection	5898760
54401540	54401563	14	+	27260156	COLO741	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.35508487595485233	[469]	[960,567,787]	7	hSpCas9	negative selection	5963036
54408768	54408791	14	+	27260156	COLO741	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.23048818421947614	[176]	[205,166,204]	-5	hSpCas9	negative selection	5963037
54417929	54417952	14	-	27260156	COLO741	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.10905484349793526	[801]	[1117,917,834]	-2	hSpCas9	negative selection	5963038
54417899	54417922	14	-	27260156	CAL120	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.30653755716093567	[723]	[1142,947,1252]	4	hSpCas9	negative selection	6020009
54417930	54417953	14	+	27260156	CAL120	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.0540621997761187	[898]	[1088,1228,1154]	0	hSpCas9	negative selection	6020010
54399895	54399918	14	-	27260156	CAL120	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.2909157306628204	[269]	[426,543,266]	4	hSpCas9	negative selection	6020011
54401540	54401563	14	+	27260156	CAL120	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.2872614548765261	[469]	[690,651,792]	4	hSpCas9	negative selection	6084287
54408768	54408791	14	+	27260156	CAL120	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.285460396794049	[176]	[294,232,280]	4	hSpCas9	negative selection	6084288
54417929	54417952	14	-	27260156	CAL120	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.45203885899388135	[801]	[818,552,827]	-6	hSpCas9	negative selection	6084289
54417899	54417922	14	-	27260156	CADOES1	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.28600161767187193	[723]	[845,802,785,849]	5	hSpCas9	negative selection	6141260
54417930	54417953	14	+	27260156	CADOES1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.26081561544152554	[898]	[1040,1026,1043,890]	4	hSpCas9	negative selection	6141261
54399895	54399918	14	-	27260156	CADOES1	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.5437340718948079	[269]	[243,399,469,349]	8	hSpCas9	negative selection	6141262
54401540	54401563	14	+	27260156	CADOES1	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.40334913659365945	[469]	[773,503,427,606]	6	hSpCas9	negative selection	6205538
54408768	54408791	14	+	27260156	CADOES1	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.34748245890794416	[176]	[213,69,108,123]	-6	hSpCas9	negative selection	6205539
54417929	54417952	14	-	27260156	CADOES1	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.13924187517181608	[801]	[586,745,838,531]	-2	hSpCas9	negative selection	6205540
54417899	54417922	14	-	27260156	EWS502	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.31583001421400325	[723]	[719,999,1071,1057]	5	hSpCas9	negative selection	6262511
54417930	54417953	14	+	27260156	EWS502	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.0030135643725746064	[898]	[898,927,960,1038]	0	hSpCas9	negative selection	6262512
54399895	54399918	14	-	27260156	EWS502	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.33918219627061497	[269]	[104,206,302,310]	-5	hSpCas9	negative selection	6262513
54401540	54401563	14	+	27260156	EWS502	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.5727367124491114	[469]	[889,749,648,642]	8	hSpCas9	negative selection	6326789
54408768	54408791	14	+	27260156	EWS502	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.06907897944927566	[176]	[137,156,261,162]	-1	hSpCas9	negative selection	6326790
54417929	54417952	14	-	27260156	EWS502	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.3002395027594177	[801]	[572,771,575,856]	-5	hSpCas9	negative selection	6326791
54417899	54417922	14	-	27260156	EW8	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.03802845875786254	[723]	[583,725,558,544]	0	hSpCas9	negative selection	6383762
54417930	54417953	14	+	27260156	EW8	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.03639819179343651	[898]	[860,648,590,774]	0	hSpCas9	negative selection	6383763
54399895	54399918	14	-	27260156	EW8	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.11303241284701881	[269]	[367,215,161,226]	2	hSpCas9	negative selection	6383764
54401540	54401563	14	+	27260156	EW8	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.4419176979301528	[469]	[678,502,380,545]	7	hSpCas9	negative selection	6448040
54408768	54408791	14	+	27260156	EW8	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.5488241385293229	[176]	[150,86,60,104]	-7	hSpCas9	negative selection	6448041
54417929	54417952	14	-	27260156	EW8	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.42965917997095604	[801]	[659,536,327,449]	-7	hSpCas9	negative selection	6448042
54417899	54417922	14	-	27260156	CORL105	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.1500233959763777	[723]	[1069,1004,899,783]	3	hSpCas9	negative selection	6505013
54417930	54417953	14	+	27260156	CORL105	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.15065007544777687	[898]	[1216,1032,1163,1261]	3	hSpCas9	negative selection	6505014
54399895	54399918	14	-	27260156	CORL105	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.11491637446909297	[269]	[427,249,399,304]	2	hSpCas9	negative selection	6505015
54401540	54401563	14	+	27260156	CORL105	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.48486041569628124	[469]	[709,893,822,656]	8	hSpCas9	negative selection	6569291
54408768	54408791	14	+	27260156	CORL105	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.13101658218814927	[176]	[199,121,274,174]	-2	hSpCas9	negative selection	6569292
54417929	54417952	14	-	27260156	CORL105	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.015753076831446666	[801]	[850,843,1198,861]	0	hSpCas9	negative selection	6569293
54417899	54417922	14	-	27260156	HS294T	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.640396128838697	[723]	[369,373,474,552]	8	hSpCas9	negative selection	6626264
54417930	54417953	14	+	27260156	HS294T	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.44952499483973685	[898]	[562,306,495,538]	6	hSpCas9	negative selection	6626265
54399895	54399918	14	-	27260156	HS294T	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.47771778127762476	[269]	[157,199,123,85]	6	hSpCas9	negative selection	6626266
54401540	54401563	14	+	27260156	HS294T	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.12252292967758764	[469]	[227,180,187,189]	1	hSpCas9	negative selection	6690542
54408768	54408791	14	+	27260156	HS294T	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.3501702131003377	[176]	[30,77,42,65]	-5	hSpCas9	negative selection	6690543
54417929	54417952	14	-	27260156	HS294T	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.04573895147642437	[801]	[267,297,226,432]	0	hSpCas9	negative selection	6690544
54417899	54417922	14	-	27260156	HCC44	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.09038544079508659	[723]	[852,677,1185,843]	1	hSpCas9	negative selection	6747515
54417930	54417953	14	+	27260156	HCC44	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.014156902181206354	[898]	[1266,708,1055,1059]	0	hSpCas9	negative selection	6747516
54399895	54399918	14	-	27260156	HCC44	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.3493513991819879	[269]	[278,395,363,494]	6	hSpCas9	negative selection	6747517
54401540	54401563	14	+	27260156	HCC44	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.5779952849394308	[469]	[737,731,1061,688]	8	hSpCas9	negative selection	6811793
54408768	54408791	14	+	27260156	HCC44	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.2905083506140127	[176]	[252,87,237,107]	-4	hSpCas9	negative selection	6811794
54417929	54417952	14	-	27260156	HCC44	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.4353996461753929	[801]	[683,510,980,581]	-6	hSpCas9	negative selection	6811795
54417899	54417922	14	-	27260156	G402	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.5293699567734884	[723]	[1796,1074,1520,789]	6	hSpCas9	negative selection	6868766
54417930	54417953	14	+	27260156	G402	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.398386028454343	[898]	[1868,1139,1640,1183]	5	hSpCas9	negative selection	6868767
54399895	54399918	14	-	27260156	G402	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.3169910368657065	[269]	[285,477,408,450]	4	hSpCas9	negative selection	6868768
54401540	54401563	14	+	27260156	G402	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.8464128882739935	[469]	[1251,771,987,1120]	9	hSpCas9	negative selection	6933044
54408768	54408791	14	+	27260156	G402	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.46456002568609467	[176]	[190,97,201,136]	-5	hSpCas9	negative selection	6933045
54417929	54417952	14	-	27260156	G402	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.4130987657574515	[801]	[820,706,563,849]	-5	hSpCas9	negative selection	6933046
54417899	54417922	14	-	27260156	L33	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.44326067341324316	[723]	[929,419,572,1070]	8	hSpCas9	negative selection	6990017
54417930	54417953	14	+	27260156	L33	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.37942621771813534	[898]	[1285,426,831,1024]	7	hSpCas9	negative selection	6990018
54399895	54399918	14	-	27260156	L33	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.017869476738154866	[269]	[323,96,189,202]	0	hSpCas9	negative selection	6990019
54401540	54401563	14	+	27260156	L33	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.4440341665920357	[469]	[569,284,378,689]	8	hSpCas9	negative selection	7054295
54408768	54408791	14	+	27260156	L33	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.022436990213448027	[176]	[192,98,91,137]	0	hSpCas9	negative selection	7054296
54417929	54417952	14	-	27260156	L33	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.20332908455482124	[801]	[690,315,414,663]	-5	hSpCas9	negative selection	7054297
54417899	54417922	14	-	27260156	K562	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.37203324521035175	[723]	[937,619,778,966]	5	hSpCas9	negative selection	7111268
54417930	54417953	14	+	27260156	K562	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.06333886816760748	[898]	[697,1081,1022,561]	0	hSpCas9	negative selection	7111269
54399895	54399918	14	-	27260156	K562	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.46194046956306	[269]	[185,74,209,214]	-5	hSpCas9	negative selection	7111270
54401540	54401563	14	+	27260156	K562	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.7572170843777849	[469]	[778,468,889,675]	8	hSpCas9	negative selection	7175546
54408768	54408791	14	+	27260156	K562	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.07952713463063721	[176]	[424,144,85,41]	1	hSpCas9	negative selection	7175547
54417929	54417952	14	-	27260156	K562	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.34254729325884564	[801]	[559,501,478,683]	-4	hSpCas9	negative selection	7175548
54417899	54417922	14	-	27260156	HT29	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.23710860287391045	[723]	[1030,1075,896,1128]	4	hSpCas9	negative selection	7232519
54417930	54417953	14	+	27260156	HT29	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.2889763114975268	[898]	[1222,1641,1159,1324]	5	hSpCas9	negative selection	7232520
54399895	54399918	14	-	27260156	HT29	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.087954029186056	[269]	[360,331,499,215]	1	hSpCas9	negative selection	7232521
54401540	54401563	14	+	27260156	HT29	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.42210425355110864	[469]	[857,926,773,545]	7	hSpCas9	negative selection	7296797
54408768	54408791	14	+	27260156	HT29	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.05899345940693035	[176]	[241,170,211,261]	1	hSpCas9	negative selection	7296798
54417929	54417952	14	-	27260156	HT29	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.025524954750659523	[801]	[1050,910,1109,777]	0	hSpCas9	negative selection	7296799
54417899	54417922	14	-	27260156	MHHES1	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.2930978042179019	[723]	[1322,1173,910,693]	5	hSpCas9	negative selection	7353770
54417930	54417953	14	+	27260156	MHHES1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.16368883304956294	[898]	[1299,942,1326,978]	3	hSpCas9	negative selection	7353771
54399895	54399918	14	-	27260156	MHHES1	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.13139007603538355	[269]	[207,428,294,197]	-2	hSpCas9	negative selection	7353772
54401540	54401563	14	+	27260156	MHHES1	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.6921534402290122	[469]	[912,1059,992,538]	9	hSpCas9	negative selection	7418048
54408768	54408791	14	+	27260156	MHHES1	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.34517893492824436	[176]	[190,239,169,58]	-6	hSpCas9	negative selection	7418049
54417929	54417952	14	-	27260156	MHHES1	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.09633378082864308	[801]	[881,949,974,621]	-2	hSpCas9	negative selection	7418050
54417899	54417922	14	-	27260156	MEWO	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.22025683539662555	[723]	[921,744,725]	5	hSpCas9	negative selection	7475021
54417930	54417953	14	+	27260156	MEWO	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.03566535853344499	[898]	[927,848,821]	0	hSpCas9	negative selection	7475022
54399895	54399918	14	-	27260156	MEWO	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.23465581646578548	[269]	[290,170,196]	-5	hSpCas9	negative selection	7475023
54401540	54401563	14	+	27260156	MEWO	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.278760029293366	[469]	[529,642,425]	6	hSpCas9	negative selection	7539299
54408768	54408791	14	+	27260156	MEWO	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.07803199507100045	[176]	[111,135,213]	-2	hSpCas9	negative selection	7539300
54417929	54417952	14	-	27260156	MEWO	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.37889035265927334	[801]	[795,443,533]	-7	hSpCas9	negative selection	7539301
54417899	54417922	14	-	27260156	LNCAPCLONEFGC	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.16060991205738628	[723]	[663,635,816,834]	2	hSpCas9	negative selection	7596272
54417930	54417953	14	+	27260156	LNCAPCLONEFGC	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.03586441368941906	[898]	[904,666,947,685]	0	hSpCas9	negative selection	7596273
54399895	54399918	14	-	27260156	LNCAPCLONEFGC	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.16539629810340817	[269]	[253,217,367,274]	2	hSpCas9	negative selection	7596274
54401540	54401563	14	+	27260156	LNCAPCLONEFGC	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.5011433194417755	[469]	[754,520,606,529]	7	hSpCas9	negative selection	7660550
54408768	54408791	14	+	27260156	LNCAPCLONEFGC	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.40467582133997393	[176]	[119,119,164,85]	-6	hSpCas9	negative selection	7660551
54417929	54417952	14	-	27260156	LNCAPCLONEFGC	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.20462454762704463	[801]	[472,491,990,630]	-3	hSpCas9	negative selection	7660552
54417899	54417922	14	-	27260156	PANC0327	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.4039180634174686	[723]	[648,837,1087,813]	6	hSpCas9	negative selection	7717523
54417930	54417953	14	+	27260156	PANC0327	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.42321052098584167	[898]	[1108,637,1189,1404]	6	hSpCas9	negative selection	7717524
54399895	54399918	14	-	27260156	PANC0327	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.2311741822466561	[269]	[363,270,204,293]	3	hSpCas9	negative selection	7717525
54401540	54401563	14	+	27260156	PANC0327	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.23751034617606015	[469]	[425,678,369,463]	3	hSpCas9	negative selection	7781801
54408768	54408791	14	+	27260156	PANC0327	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.6658925880399662	[176]	[105,97,60,131]	-7	hSpCas9	negative selection	7781802
54417929	54417952	14	-	27260156	PANC0327	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.6883873591446142	[801]	[408,392,525,443]	-7	hSpCas9	negative selection	7781803
54417899	54417922	14	-	27260156	NCIH2009	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.5763728326003601	[723]	[2004,1206,1413]	7	hSpCas9	negative selection	7838774
54417930	54417953	14	+	27260156	NCIH2009	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.31241923747075506	[898]	[1851,1247,1639]	4	hSpCas9	negative selection	7838775
54399895	54399918	14	-	27260156	NCIH2009	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.2366363203202111	[269]	[447,408,476]	3	hSpCas9	negative selection	7838776
54401540	54401563	14	+	27260156	NCIH2009	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.41333472254211917	[469]	[877,695,1051]	6	hSpCas9	negative selection	7903052
54408768	54408791	14	+	27260156	NCIH2009	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.12046337196576373	[176]	[149,158,358]	-2	hSpCas9	negative selection	7903053
54417929	54417952	14	-	27260156	NCIH2009	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.020504278264188325	[801]	[1509,958,925]	0	hSpCas9	negative selection	7903054
54417899	54417922	14	-	27260156	NCIH1373	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.5946810564309541	[723]	[1162,896,1035,490]	6	hSpCas9	negative selection	7960025
54417930	54417953	14	+	27260156	NCIH1373	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.4203796842985137	[898]	[1700,1074,1085,428]	4	hSpCas9	negative selection	7960026
54399895	54399918	14	-	27260156	NCIH1373	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.6443374225748764	[269]	[376,268,901,86]	6	hSpCas9	negative selection	7960027
54401540	54401563	14	+	27260156	NCIH1373	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	1.2035304111681848	[469]	[1166,1515,1464,161]	9	hSpCas9	negative selection	8024303
54408768	54408791	14	+	27260156	NCIH1373	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.17724100809519894	[176]	[307,109,417,18]	1	hSpCas9	negative selection	8024304
54417929	54417952	14	-	27260156	NCIH1373	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.7681555898402469	[801]	[342,434,682,165]	-6	hSpCas9	negative selection	8024305
54417899	54417922	14	-	27260156	PATU8902	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.20766912188782627	[723]	[1065,897,962,1856]	2	hSpCas9	negative selection	8081276
54417930	54417953	14	+	27260156	PATU8902	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.09701488691656834	[898]	[1196,1469,1121,1652]	1	hSpCas9	negative selection	8081277
54399895	54399918	14	-	27260156	PATU8902	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.411939622951109	[269]	[493,551,276,763]	4	hSpCas9	negative selection	8081278
54401540	54401563	14	+	27260156	PATU8902	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.9090162997179824	[469]	[1447,804,997,1776]	8	hSpCas9	negative selection	8145554
54408768	54408791	14	+	27260156	PATU8902	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.25811786520275315	[176]	[156,163,290,186]	-3	hSpCas9	negative selection	8145555
54417929	54417952	14	-	27260156	PATU8902	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.5305222269898426	[801]	[637,877,479,1222]	-5	hSpCas9	negative selection	8145556
54417899	54417922	14	-	27260156	PANC1	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.12043296390341618	[723]	[547,983,842,426]	2	hSpCas9	negative selection	8202527
54417930	54417953	14	+	27260156	PANC1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.04241922465189407	[898]	[806,1020,675,720]	0	hSpCas9	negative selection	8202528
54399895	54399918	14	-	27260156	PANC1	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.6148854233201437	[269]	[277,502,327,339]	8	hSpCas9	negative selection	8202529
54401540	54401563	14	+	27260156	PANC1	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.5473176715555438	[469]	[494,551,720,578]	8	hSpCas9	negative selection	8266805
54408768	54408791	14	+	27260156	PANC1	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.38349556024252207	[176]	[190,148,68,67]	-5	hSpCas9	negative selection	8266806
54417929	54417952	14	-	27260156	PANC1	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.3992700106593469	[801]	[438,679,543,461]	-6	hSpCas9	negative selection	8266807
54417899	54417922	14	-	27260156	PANC0813	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.4349475253212338	[723]	[1435,1247,1105,849]	7	hSpCas9	negative selection	8323778
54417930	54417953	14	+	27260156	PANC0813	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.03808860277891102	[898]	[1228,1148,840,1125]	0	hSpCas9	negative selection	8323779
54399895	54399918	14	-	27260156	PANC0813	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.33721607484925253	[269]	[247,201,237,311]	-5	hSpCas9	negative selection	8323780
54401540	54401563	14	+	27260156	PANC0813	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.31891587258225124	[469]	[706,669,805,578]	5	hSpCas9	negative selection	8388056
54408768	54408791	14	+	27260156	PANC0813	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.7764328017073694	[176]	[151,122,142,72]	-8	hSpCas9	negative selection	8388057
54417929	54417952	14	-	27260156	PANC0813	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.5762765169689458	[801]	[706,536,821,476]	-7	hSpCas9	negative selection	8388058
54417899	54417922	14	-	27260156	RDES	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.268448754308121	[723]	[878,936,888,1357]	4	hSpCas9	negative selection	8445029
54417930	54417953	14	+	27260156	RDES	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.01872914339694831	[898]	[888,980,1234,1108]	0	hSpCas9	negative selection	8445030
54399895	54399918	14	-	27260156	RDES	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.33070832683293344	[269]	[334,266,419,582]	5	hSpCas9	negative selection	8445031
54401540	54401563	14	+	27260156	RDES	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.5383270803077259	[469]	[596,781,933,861]	8	hSpCas9	negative selection	8509307
54408768	54408791	14	+	27260156	RDES	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.1462727787689233	[176]	[223,194,199,285]	2	hSpCas9	negative selection	8509308
54417929	54417952	14	-	27260156	RDES	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.18937353389263234	[801]	[652,691,944,1000]	-3	hSpCas9	negative selection	8509309
54417899	54417922	14	-	27260156	PC3	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	-0.03590629162774284	[723]	[405,654,1457,658]	-1	hSpCas9	negative selection	8566280
54417930	54417953	14	+	27260156	PC3	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.1580210469366441	[898]	[551,759,1328,803]	-4	hSpCas9	negative selection	8566281
54399895	54399918	14	-	27260156	PC3	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.015568519188593588	[269]	[254,159,370,318]	0	hSpCas9	negative selection	8566282
54401540	54401563	14	+	27260156	PC3	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.34886887183931814	[469]	[347,521,982,749]	7	hSpCas9	negative selection	8630558
54408768	54408791	14	+	27260156	PC3	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.09893187902770006	[176]	[121,219,138,163]	-2	hSpCas9	negative selection	8630559
54417929	54417952	14	-	27260156	PC3	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-1.083170494460052	[801]	[276,326,603,394]	-9	hSpCas9	negative selection	8630560
54417899	54417922	14	-	27260156	PATU8988T	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.2929917613768138	[723]	[944,756,673,1061]	5	hSpCas9	negative selection	8687531
54417930	54417953	14	+	27260156	PATU8988T	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.09293655743010443	[898]	[706,1035,1019,953]	1	hSpCas9	negative selection	8687532
54399895	54399918	14	-	27260156	PATU8988T	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.2863428679156661	[269]	[254,441,268,318]	5	hSpCas9	negative selection	8687533
54401540	54401563	14	+	27260156	PATU8988T	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.5831060635664694	[469]	[582,929,586,642]	8	hSpCas9	negative selection	8751809
54408768	54408791	14	+	27260156	PATU8988T	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.4580053667327415	[176]	[89,72,224,101]	-6	hSpCas9	negative selection	8751810
54417929	54417952	14	-	27260156	PATU8988T	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.1884367687178875	[801]	[653,750,596,729]	-3	hSpCas9	negative selection	8751811
54417899	54417922	14	-	27260156	T47D	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.2418486272408824	[723]	[1103,857,1063,973]	5	hSpCas9	negative selection	8808782
54417930	54417953	14	+	27260156	T47D	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.05867671056081991	[898]	[1078,961,1130,1204]	1	hSpCas9	negative selection	8808783
54399895	54399918	14	-	27260156	T47D	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.04597082146354181	[269]	[366,262,242,351]	-1	hSpCas9	negative selection	8808784
54401540	54401563	14	+	27260156	T47D	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.4921271072031165	[469]	[818,667,818,782]	8	hSpCas9	negative selection	8873060
54408768	54408791	14	+	27260156	T47D	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.2327397022992499	[176]	[178,137,243,141]	-5	hSpCas9	negative selection	8873061
54417929	54417952	14	-	27260156	T47D	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.278693502619416	[801]	[795,670,667,961]	-6	hSpCas9	negative selection	8873062
54417899	54417922	14	-	27260156	SU8686	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.36924292020249283	[723]	[753,799,1045,1182]	6	hSpCas9	negative selection	8930033
54417930	54417953	14	+	27260156	SU8686	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.28353923028399497	[898]	[1011,994,1042,1341]	5	hSpCas9	negative selection	8930034
54399895	54399918	14	-	27260156	SU8686	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.07187877050569524	[269]	[172,267,358,221]	-1	hSpCas9	negative selection	8930035
54401540	54401563	14	+	27260156	SU8686	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.652647291196497	[469]	[572,595,751,1099]	9	hSpCas9	negative selection	8994311
54408768	54408791	14	+	27260156	SU8686	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.8560401081276445	[176]	[91,99,99,94]	-8	hSpCas9	negative selection	8994312
54417929	54417952	14	-	27260156	SU8686	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.042331096883138075	[801]	[466,808,738,1159]	0	hSpCas9	negative selection	8994313
54417899	54417922	14	-	27260156	SKES1	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.22341606504157507	[723]	[1116,855,801,651]	5	hSpCas9	negative selection	9051284
54417930	54417953	14	+	27260156	SKES1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.09249922448080783	[898]	[1006,979,749,678]	-2	hSpCas9	negative selection	9051285
54399895	54399918	14	-	27260156	SKES1	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.08239144127741183	[269]	[324,306,275,242]	1	hSpCas9	negative selection	9051286
54401540	54401563	14	+	27260156	SKES1	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.6167151144369861	[469]	[700,955,783,480]	9	hSpCas9	negative selection	9115562
54408768	54408791	14	+	27260156	SKES1	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.41591338535503475	[176]	[159,114,92,158]	-7	hSpCas9	negative selection	9115563
54417929	54417952	14	-	27260156	SKES1	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.24285987878068926	[801]	[708,613,570,787]	-5	hSpCas9	negative selection	9115564
54417899	54417922	14	-	27260156	TOV112D	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.2825118494830854	[723]	[842,1151,871,726]	5	hSpCas9	negative selection	9172535
54417930	54417953	14	+	27260156	TOV112D	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.032349247499986244	[898]	[1012,1021,925,757]	0	hSpCas9	negative selection	9172536
54399895	54399918	14	-	27260156	TOV112D	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	0.5411475182174441	[269]	[350,518,422,309]	8	hSpCas9	negative selection	9172537
54401540	54401563	14	+	27260156	TOV112D	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.4545441145470497	[469]	[567,859,494,700]	8	hSpCas9	negative selection	9236813
54408768	54408791	14	+	27260156	TOV112D	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	0.514037717308779	[176]	[136,323,310,247]	8	hSpCas9	negative selection	9236814
54417929	54417952	14	-	27260156	TOV112D	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.23909055664319034	[801]	[767,784,548,652]	-5	hSpCas9	negative selection	9236815
54417899	54417922	14	-	27260156	TC71	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.28019110142733095	[723]	[834,887,950,1107]	6	hSpCas9	negative selection	9293786
54417930	54417953	14	+	27260156	TC71	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.13497140092732685	[898]	[1174,991,963,1104]	3	hSpCas9	negative selection	9293787
54399895	54399918	14	-	27260156	TC71	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.14719374864904444	[269]	[258,325,234,223]	-4	hSpCas9	negative selection	9293788
54401540	54401563	14	+	27260156	TC71	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.4380842679742631	[469]	[630,702,726,667]	8	hSpCas9	negative selection	9358064
54408768	54408791	14	+	27260156	TC71	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.2809542425804157	[176]	[126,194,152,149]	-6	hSpCas9	negative selection	9358065
54417929	54417952	14	-	27260156	TC71	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.2124115811524574	[801]	[716,872,677,699]	-5	hSpCas9	negative selection	9358066
54417899	54417922	14	-	27260156	TC32	viability	TAGGTCTCGCAGGCTGTCTATGG	CDKN3	ENSG00000100526	0.34017032633282085	[723]	[761,638,1012,1117]	6	hSpCas9	negative selection	9415037
54417930	54417953	14	+	27260156	TC32	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.14445832893727206	[898]	[852,620,1203,1193]	2	hSpCas9	negative selection	9415038
54399895	54399918	14	-	27260156	TC32	viability	CTCACTTGTTTGTATTGAACTGG	CDKN3	ENSG00000100526	-0.24494963406555104	[269]	[196,115,328,264]	-4	hSpCas9	negative selection	9415039
54401540	54401563	14	+	27260156	TC32	viability	GTGAATTGTTCTCAGTTTCTCGG	CDKN3	ENSG00000100526	0.4834274444725497	[469]	[594,346,931,727]	7	hSpCas9	negative selection	9479315
54408768	54408791	14	+	27260156	TC32	viability	AGAAATGTCCAAAAAGATACAGG	CDKN3	ENSG00000100526	-0.09747564921249907	[176]	[132,151,185,149]	-2	hSpCas9	negative selection	9479316
54417929	54417952	14	-	27260156	TC32	viability	CTTGATGGTCTGTATTGCCCCGG	CDKN3	ENSG00000100526	-0.3529126830114375	[801]	[531,356,874,715]	-6	hSpCas9	negative selection	9479317
54401561	54401584	14	+	27869803	HPAFII	viability after 27 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-1.058781543611335	[66]	[5,25,NaN]	-6	hSpCas9	negative selection	9551766
54411563	54411586	14	-	27869803	HPAFII	viability after 27 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.42332670748342505	[47]	[32,6,NaN]	-3	hSpCas9	negative selection	9551767
54411600	54411623	14	+	27869803	HPAFII	viability after 27 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	1.011705819242151	[161]	[156,183,NaN]	8	hSpCas9	negative selection	9551768
54417870	54417893	14	-	27869803	HPAFII	viability after 27 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.004035344762135962	[597]	[443,207,NaN]	0	hSpCas9	negative selection	9551769
54401561	54401584	14	+	27869803	HPAFII	viability after 15 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-1.491055936894942	[66]	[24,25,NaN]	-8	hSpCas9	negative selection	9634215
54411563	54411586	14	-	27869803	HPAFII	viability after 15 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.059425691989026586	[47]	[104,14,NaN]	0	hSpCas9	negative selection	9634216
54411600	54411623	14	+	27869803	HPAFII	viability after 15 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.4573944228914761	[161]	[325,184,NaN]	5	hSpCas9	negative selection	9634217
54417870	54417893	14	-	27869803	HPAFII	viability after 15 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.38337483446604903	[597]	[1182,623,NaN]	4	hSpCas9	negative selection	9634218
54401561	54401584	14	+	27869803	ASPC1	viability after 36 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	1.6108705926658875	[156]	[202,74,213]	9	hSpCas9	negative selection	9716664
54411563	54411586	14	-	27869803	ASPC1	viability after 36 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.6832220818634922	[76]	[98,0,36]	6	hSpCas9	negative selection	9716665
54411600	54411623	14	+	27869803	ASPC1	viability after 36 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	1.065194765533747	[413]	[252,402,253]	8	hSpCas9	negative selection	9716666
54417870	54417893	14	-	27869803	ASPC1	viability after 36 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	-0.014186766855751598	[1356]	[263,463,611]	0	hSpCas9	negative selection	9716667
54401561	54401584	14	+	27869803	PATU8988S	viability after 35 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.9131910966515069	[84]	[50,77,NaN]	8	hSpCas9	negative selection	9799113
54411563	54411586	14	-	27869803	PATU8988S	viability after 35 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.5155168254527678	[132]	[24,49,NaN]	-5	hSpCas9	negative selection	9799114
54411600	54411623	14	+	27869803	PATU8988S	viability after 35 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.2928440325651907	[425]	[162,116,NaN]	-3	hSpCas9	negative selection	9799115
54417870	54417893	14	-	27869803	PATU8988S	viability after 35 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	-0.1925397968458038	[1083]	[397,365,NaN]	-2	hSpCas9	negative selection	9799116
54401561	54401584	14	+	27869803	PATU8988S	viability after 31 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	0.7337479358766223	[84]	[69,38,NaN]	8	hSpCas9	negative selection	9881562
54411563	54411586	14	-	27869803	PATU8988S	viability after 31 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.0052839240100710505	[132]	[47,58,NaN]	0	hSpCas9	negative selection	9881563
54411600	54411623	14	+	27869803	PATU8988S	viability after 31 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	-0.38589978071551895	[425]	[118,143,NaN]	-4	hSpCas9	negative selection	9881564
54417870	54417893	14	-	27869803	PATU8988S	viability after 31 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.0018536744429259455	[1083]	[401,471,NaN]	0	hSpCas9	negative selection	9881565
54401561	54401584	14	+	27869803	HPAFII	viability after 35 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-0.4509048985732924	[66]	[5,45,NaN]	-3	hSpCas9	negative selection	9964011
54411563	54411586	14	-	27869803	HPAFII	viability after 35 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.6400579375179705	[47]	[24,4,NaN]	-4	hSpCas9	negative selection	9964012
54411600	54411623	14	+	27869803	HPAFII	viability after 35 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.9737574143109051	[161]	[58,275,NaN]	6	hSpCas9	negative selection	9964013
54417870	54417893	14	-	27869803	HPAFII	viability after 35 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.2749858936981404	[597]	[505,208,NaN]	1	hSpCas9	negative selection	9964014
54401561	54401584	14	+	27869803	HPAFII	viability after 31 days	GGTTTATGTGCTCTTCCAGGTGG	CDKN3	ENSG00000100526	-0.6785677148920792	[66]	[0,47,NaN]	-4	hSpCas9	negative selection	10046460
54411563	54411586	14	-	27869803	HPAFII	viability after 31 days	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.31111019536944573	[47]	[53,10,NaN]	2	hSpCas9	negative selection	10046461
54411600	54411623	14	+	27869803	HPAFII	viability after 31 days	CATCATCATCCAATCGCAGATGG	CDKN3	ENSG00000100526	0.7006052612354624	[161]	[119,177,NaN]	5	hSpCas9	negative selection	10046462
54417870	54417893	14	-	27869803	HPAFII	viability after 31 days	CTGGTGATATTGTGTCAGACAGG	CDKN3	ENSG00000100526	0.31117103592339657	[597]	[547,272,NaN]	2	hSpCas9	negative selection	10046463
54411480	54411503	14	+	28162770	P31FUJ	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.4939132930580703	[225]	[373]	5	hSpCas9	negative selection	10130960
54417889	54417912	14	-	28162770	P31FUJ	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.2868688360550584	[112]	[161]	3	hSpCas9	negative selection	10130961
54417912	54417935	14	+	28162770	P31FUJ	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.20914198749407753	[331]	[450]	2	hSpCas9	negative selection	10130962
54411563	54411586	14	-	28162770	P31FUJ	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.25262462275586295	[209]	[293]	2	hSpCas9	negative selection	10130963
54397056	54397079	14	+	28162770	P31FUJ	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	1.5094000381179744	[54]	[183]	9	hSpCas9	negative selection	10130964
54417930	54417953	14	+	28162770	P31FUJ	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.42281484987056306	[258]	[407]	5	hSpCas9	negative selection	10130965
54411609	54411632	14	-	28162770	P31FUJ	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.4795396027830053	[129]	[212]	5	hSpCas9	negative selection	10130966
54415895	54415918	14	+	28162770	P31FUJ	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.6461384093488397	[409]	[753]	7	hSpCas9	negative selection	10130967
54415909	54415932	14	+	28162770	P31FUJ	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.6860610328602158	[127]	[241]	7	hSpCas9	negative selection	10130968
54411515	54411538	14	+	28162770	P31FUJ	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.8513832154995793	[673]	[1428]	8	hSpCas9	negative selection	10130969
54411480	54411503	14	+	28162770	TF1	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10300326
54417889	54417912	14	-	28162770	TF1	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10300327
54417912	54417935	14	+	28162770	TF1	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	NaN	[NaN]	[227]	1	hSpCas9	negative selection	10300328
54411563	54411586	14	-	28162770	TF1	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10300329
54397056	54397079	14	+	28162770	TF1	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10300330
54417930	54417953	14	+	28162770	TF1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10300331
54411609	54411632	14	-	28162770	TF1	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	NaN	[NaN]	[266]	1	hSpCas9	negative selection	10300332
54415895	54415918	14	+	28162770	TF1	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10300333
54415909	54415932	14	+	28162770	TF1	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10300334
54411515	54411538	14	+	28162770	TF1	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	NaN	[NaN]	[827]	1	hSpCas9	negative selection	10300335
54411480	54411503	14	+	28162770	SKM1	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.641654506477017	[61]	[170]	6	hSpCas9	negative selection	10469692
54417889	54417912	14	-	28162770	SKM1	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.1779983019779947	[16]	[33]	1	hSpCas9	negative selection	10469693
54417912	54417935	14	+	28162770	SKM1	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	1.2852923151499032	[67]	[292]	9	hSpCas9	negative selection	10469694
54411563	54411586	14	-	28162770	SKM1	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.7290134707758129	[42]	[125]	7	hSpCas9	negative selection	10469695
54397056	54397079	14	+	28162770	SKM1	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	-0.45003292063504774	[16]	[21]	-4	hSpCas9	negative selection	10469696
54417930	54417953	14	+	28162770	SKM1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.627801219417515	[81]	[223]	6	hSpCas9	negative selection	10469697
54411609	54411632	14	-	28162770	SKM1	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.4285417636285914	[28]	[68]	4	hSpCas9	negative selection	10469698
54415895	54415918	14	+	28162770	SKM1	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.8434106351191665	[92]	[294]	7	hSpCas9	negative selection	10469699
54415909	54415932	14	+	28162770	SKM1	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	1.802489166885788	[29]	[184]	9	hSpCas9	negative selection	10469700
54411515	54411538	14	+	28162770	SKM1	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.8766175844947179	[121]	[395]	8	hSpCas9	negative selection	10469701
54411480	54411503	14	+	28162770	SKM1	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.641654506477017	[61]	[170]	6	hSpCas9	negative selection	10639058
54417889	54417912	14	-	28162770	SKM1	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.1779983019779947	[16]	[33]	1	hSpCas9	negative selection	10639059
54417912	54417935	14	+	28162770	SKM1	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	1.2852923151499032	[67]	[292]	9	hSpCas9	negative selection	10639060
54411563	54411586	14	-	28162770	SKM1	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.7290134707758129	[42]	[125]	7	hSpCas9	negative selection	10639061
54397056	54397079	14	+	28162770	SKM1	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	-0.45003292063504774	[16]	[21]	-4	hSpCas9	negative selection	10639062
54417930	54417953	14	+	28162770	SKM1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.627801219417515	[81]	[223]	6	hSpCas9	negative selection	10639063
54411609	54411632	14	-	28162770	SKM1	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.4285417636285914	[28]	[68]	4	hSpCas9	negative selection	10639064
54415895	54415918	14	+	28162770	SKM1	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.8434106351191665	[92]	[294]	7	hSpCas9	negative selection	10639065
54415909	54415932	14	+	28162770	SKM1	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	1.802489166885788	[29]	[184]	9	hSpCas9	negative selection	10639066
54411515	54411538	14	+	28162770	SKM1	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.8766175844947179	[121]	[395]	8	hSpCas9	negative selection	10639067
54411480	54411503	14	+	28162770	PL21	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	-0.5938569247132648	[214]	[61]	-4	hSpCas9	negative selection	10808424
54417889	54417912	14	-	28162770	PL21	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	-0.46612298833368415	[72]	[22]	-3	hSpCas9	negative selection	10808425
54417912	54417935	14	+	28162770	PL21	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	1.381018197331759	[276]	[313]	9	hSpCas9	negative selection	10808426
54411563	54411586	14	-	28162770	PL21	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.538725053330291	[154]	[97]	5	hSpCas9	negative selection	10808427
54397056	54397079	14	+	28162770	PL21	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	0.2266118258505112	[107]	[54]	2	hSpCas9	negative selection	10808428
54417930	54417953	14	+	28162770	PL21	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.1802841297081867	[301]	[115]	-1	hSpCas9	negative selection	10808429
54411609	54411632	14	-	28162770	PL21	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	1.904315273537857	[88]	[144]	9	hSpCas9	negative selection	10808430
54415895	54415918	14	+	28162770	PL21	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.5071944328951521	[311]	[192]	4	hSpCas9	negative selection	10808431
54415909	54415932	14	+	28162770	PL21	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.12537184608734786	[98]	[46]	1	hSpCas9	negative selection	10808432
54411515	54411538	14	+	28162770	PL21	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.2833335500157188	[437]	[231]	2	hSpCas9	negative selection	10808433
54411480	54411503	14	+	28162770	P31FUJ	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.4939132930580703	[225]	[373]	5	hSpCas9	negative selection	10977790
54417889	54417912	14	-	28162770	P31FUJ	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.2868688360550584	[112]	[161]	3	hSpCas9	negative selection	10977791
54417912	54417935	14	+	28162770	P31FUJ	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.20914198749407753	[331]	[450]	2	hSpCas9	negative selection	10977792
54411563	54411586	14	-	28162770	P31FUJ	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.25262462275586295	[209]	[293]	2	hSpCas9	negative selection	10977793
54397056	54397079	14	+	28162770	P31FUJ	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	1.5094000381179744	[54]	[183]	9	hSpCas9	negative selection	10977794
54417930	54417953	14	+	28162770	P31FUJ	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.42281484987056306	[258]	[407]	5	hSpCas9	negative selection	10977795
54411609	54411632	14	-	28162770	P31FUJ	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.4795396027830053	[129]	[212]	5	hSpCas9	negative selection	10977796
54415895	54415918	14	+	28162770	P31FUJ	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.6461384093488397	[409]	[753]	7	hSpCas9	negative selection	10977797
54415909	54415932	14	+	28162770	P31FUJ	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.6860610328602158	[127]	[241]	7	hSpCas9	negative selection	10977798
54411515	54411538	14	+	28162770	P31FUJ	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.8513832154995793	[673]	[1428]	8	hSpCas9	negative selection	10977799
54411480	54411503	14	+	28162770	OCIAML5	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.12607399517226353	[132]	[261]	1	hSpCas9	negative selection	11147156
54417889	54417912	14	-	28162770	OCIAML5	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	-1.9723608045817087	[49]	[22]	-8	hSpCas9	negative selection	11147157
54417912	54417935	14	+	28162770	OCIAML5	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.5035446502796541	[126]	[324]	4	hSpCas9	negative selection	11147158
54411563	54411586	14	-	28162770	OCIAML5	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.44226396545933544	[94]	[232]	4	hSpCas9	negative selection	11147159
54397056	54397079	14	+	28162770	OCIAML5	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	-0.19998987428430393	[62]	[98]	-1	hSpCas9	negative selection	11147160
54417930	54417953	14	+	28162770	OCIAML5	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.334319150239095	[226]	[324]	-2	hSpCas9	negative selection	11147161
54411609	54411632	14	-	28162770	OCIAML5	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.8848565059816664	[88]	[86]	-5	hSpCas9	negative selection	11147162
54415895	54415918	14	+	28162770	OCIAML5	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.5654058573319006	[221]	[592]	5	hSpCas9	negative selection	11147163
54415909	54415932	14	+	28162770	OCIAML5	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	-0.28459149687168184	[82]	[122]	-2	hSpCas9	negative selection	11147164
54411515	54411538	14	+	28162770	OCIAML5	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.9020887845997243	[291]	[984]	7	hSpCas9	negative selection	11147165
54411480	54411503	14	+	28162770	EOL1	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.3335614832216085	[359]	[238]	3	hSpCas9	negative selection	11316522
54417889	54417912	14	-	28162770	EOL1	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	-0.2860192143691238	[80]	[34]	-2	hSpCas9	negative selection	11316523
54417912	54417935	14	+	28162770	EOL1	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.24382628804394746	[544]	[339]	2	hSpCas9	negative selection	11316524
54411563	54411586	14	-	28162770	EOL1	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.23782255469846922	[300]	[186]	2	hSpCas9	negative selection	11316525
54397056	54397079	14	+	28162770	EOL1	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	0.8122815393196223	[186]	[172]	7	hSpCas9	negative selection	11316526
54417930	54417953	14	+	28162770	EOL1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.5175475913571091	[536]	[404]	5	hSpCas9	negative selection	11316527
54411609	54411632	14	-	28162770	EOL1	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-1.343224553269922	[182]	[37]	-7	hSpCas9	negative selection	11316528
54415895	54415918	14	+	28162770	EOL1	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.6225192341208771	[359]	[291]	5	hSpCas9	negative selection	11316529
54415909	54415932	14	+	28162770	EOL1	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.7302789511484745	[126]	[110]	6	hSpCas9	negative selection	11316530
54411515	54411538	14	+	28162770	EOL1	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.09144508031527909	[635]	[356]	0	hSpCas9	negative selection	11316531
54411480	54411503	14	+	28162770	MOLM13	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.46267167227355943	[276]	[275]	3	hSpCas9	negative selection	11485888
54417889	54417912	14	-	28162770	MOLM13	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.6112535567157562	[66]	[73]	4	hSpCas9	negative selection	11485889
54417912	54417935	14	+	28162770	MOLM13	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	1.441821909992716	[362]	[712]	9	hSpCas9	negative selection	11485890
54411563	54411586	14	-	28162770	MOLM13	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	1.4799119097937918	[238]	[481]	9	hSpCas9	negative selection	11485891
54397056	54397079	14	+	28162770	MOLM13	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	-2.664560914479071	[113]	[12]	-8	hSpCas9	negative selection	11485892
54417930	54417953	14	+	28162770	MOLM13	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	1.2425472657827354	[407]	[697]	8	hSpCas9	negative selection	11485893
54411609	54411632	14	-	28162770	MOLM13	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.51988401918284	[108]	[112]	4	hSpCas9	negative selection	11485894
54415895	54415918	14	+	28162770	MOLM13	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.699896891757748	[469]	[551]	5	hSpCas9	negative selection	11485895
54415909	54415932	14	+	28162770	MOLM13	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	-1.3726324044482245	[153]	[42]	-6	hSpCas9	negative selection	11485896
54411515	54411538	14	+	28162770	MOLM13	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.32360732516358204	[703]	[636]	2	hSpCas9	negative selection	11485897
54411480	54411503	14	+	28162770	HEL	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.3649578407973767	[353]	[291]	3	hSpCas9	negative selection	11655254
54417889	54417912	14	-	28162770	HEL	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	1.3032523657286899	[30]	[48]	9	hSpCas9	negative selection	11655255
54417912	54417935	14	+	28162770	HEL	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	1.0445526361230357	[273]	[361]	8	hSpCas9	negative selection	11655256
54411563	54411586	14	-	28162770	HEL	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.7329366409719352	[247]	[263]	6	hSpCas9	negative selection	11655257
54397056	54397079	14	+	28162770	HEL	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	0.5946445437993119	[121]	[117]	5	hSpCas9	negative selection	11655258
54417930	54417953	14	+	28162770	HEL	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	1.0917693723523527	[366]	[500]	8	hSpCas9	negative selection	11655259
54411609	54411632	14	-	28162770	HEL	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.17439711084983278	[110]	[62]	-1	hSpCas9	negative selection	11655260
54415895	54415918	14	+	28162770	HEL	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	1.0284820244851627	[397]	[519]	8	hSpCas9	negative selection	11655261
54415909	54415932	14	+	28162770	HEL	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	-0.27373781243735973	[150]	[79]	-2	hSpCas9	negative selection	11655262
54411515	54411538	14	+	28162770	HEL	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	1.138064120236837	[497]	[701]	8	hSpCas9	negative selection	11655263
54411480	54411503	14	+	28162770	MV411	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.3242531478336062	[255]	[269]	3	hSpCas9	negative selection	11824620
54417889	54417912	14	-	28162770	MV411	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.7844655744402294	[50]	[73]	7	hSpCas9	negative selection	11824621
54417912	54417935	14	+	28162770	MV411	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	-1.1035390766150857	[300]	[117]	-6	hSpCas9	negative selection	11824622
54411563	54411586	14	-	28162770	MV411	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.8236298418761994	[164]	[245]	7	hSpCas9	negative selection	11824623
54397056	54397079	14	+	28162770	MV411	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	-0.3740508259634947	[79]	[51]	-3	hSpCas9	negative selection	11824624
54417930	54417953	14	+	28162770	MV411	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.44773620126860625	[328]	[377]	4	hSpCas9	negative selection	11824625
54411609	54411632	14	-	28162770	MV411	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.6569847892349936	[72]	[38]	-5	hSpCas9	negative selection	11824626
54415895	54415918	14	+	28162770	MV411	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.40918862077938756	[294]	[329]	3	hSpCas9	negative selection	11824627
54415909	54415932	14	+	28162770	MV411	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.9365084548446698	[97]	[157]	8	hSpCas9	negative selection	11824628
54411515	54411538	14	+	28162770	MV411	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.6938130165946261	[443]	[604]	6	hSpCas9	negative selection	11824629
54411480	54411503	14	+	28162770	MONOMAC1	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	1.9217006995239694	[101]	[442]	9	hSpCas9	negative selection	11993986
54417889	54417912	14	-	28162770	MONOMAC1	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.0022719611638528647	[26]	[30]	0	hSpCas9	negative selection	11993987
54417912	54417935	14	+	28162770	MONOMAC1	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.020380758861602066	[165]	[192]	0	hSpCas9	negative selection	11993988
54411563	54411586	14	-	28162770	MONOMAC1	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.2322262755218536	[82]	[80]	-2	hSpCas9	negative selection	11993989
54397056	54397079	14	+	28162770	MONOMAC1	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	1.6662268161487068	[46]	[170]	9	hSpCas9	negative selection	11993990
54417930	54417953	14	+	28162770	MONOMAC1	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	-0.22892090807933974	[182]	[178]	-2	hSpCas9	negative selection	11993991
54411609	54411632	14	-	28162770	MONOMAC1	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	0.8162599755539042	[53]	[108]	7	hSpCas9	negative selection	11993992
54415895	54415918	14	+	28162770	MONOMAC1	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.10034906356501727	[165]	[203]	1	hSpCas9	negative selection	11993993
54415909	54415932	14	+	28162770	MONOMAC1	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	-0.4160466290013495	[70]	[60]	-4	hSpCas9	negative selection	11993994
54411515	54411538	14	+	28162770	MONOMAC1	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	-0.22964151249148146	[357]	[349]	-2	hSpCas9	negative selection	11993995
54411480	54411503	14	+	28162770	OCIAML2	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.5688985389444761	[44]	[369]	5	hSpCas9	negative selection	12163352
54417889	54417912	14	-	28162770	OCIAML2	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	0.5492697321955438	[8]	[72]	5	hSpCas9	negative selection	12163353
54417912	54417935	14	+	28162770	OCIAML2	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.49653878229046633	[49]	[390]	5	hSpCas9	negative selection	12163354
54411563	54411586	14	-	28162770	OCIAML2	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	-0.06623957016282586	[33]	[179]	0	hSpCas9	negative selection	12163355
54397056	54397079	14	+	28162770	OCIAML2	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	1.6723281285998817	[11]	[211]	9	hSpCas9	negative selection	12163356
54417930	54417953	14	+	28162770	OCIAML2	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.7716621535319915	[53]	[510]	7	hSpCas9	negative selection	12163357
54411609	54411632	14	-	28162770	OCIAML2	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	-0.47062982524216124	[15]	[63]	-4	hSpCas9	negative selection	12163358
54415895	54415918	14	+	28162770	OCIAML2	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	0.6507383560219504	[46]	[408]	6	hSpCas9	negative selection	12163359
54415909	54415932	14	+	28162770	OCIAML2	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.607372686759112	[17]	[151]	6	hSpCas9	negative selection	12163360
54411515	54411538	14	+	28162770	OCIAML2	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	0.6509996191593699	[80]	[704]	6	hSpCas9	negative selection	12163361
54411480	54411503	14	+	28162770	OCIAML3	viability	GCAGAAGAACTAAAGAGCTGTGG	CDKN3	ENSG00000100526	0.6629006627127891	[58]	[281]	6	hSpCas9	negative selection	12332718
54417889	54417912	14	-	28162770	OCIAML3	viability	AGGCTGTCTATGGCTTGCTCTGG	CDKN3	ENSG00000100526	-0.09924294857458538	[10]	[30]	-1	hSpCas9	negative selection	12332719
54417912	54417935	14	+	28162770	OCIAML3	viability	GCGAGACCTAAGAGGATCCGGGG	CDKN3	ENSG00000100526	0.6740977550570528	[70]	[341]	6	hSpCas9	negative selection	12332720
54411563	54411586	14	-	28162770	OCIAML3	viability	ATTGCTGGTAGAGATCCAGAAGG	CDKN3	ENSG00000100526	0.6147098441152082	[52]	[244]	5	hSpCas9	negative selection	12332721
54397056	54397079	14	+	28162770	OCIAML3	viability	GGGGCGGCCAGCGATGAAGCCGG	CDKN3	ENSG00000100526	0.7036729083165219	[23]	[117]	6	hSpCas9	negative selection	12332722
54417930	54417953	14	+	28162770	OCIAML3	viability	CGGGGCAATACAGACCATCAAGG	CDKN3	ENSG00000100526	0.3668217623951591	[55]	[217]	3	hSpCas9	negative selection	12332723
54411609	54411632	14	-	28162770	OCIAML3	viability	GGAGTCCCTCCATCTGCGATTGG	CDKN3	ENSG00000100526	1.6076262208454872	[19]	[183]	9	hSpCas9	negative selection	12332724
54415895	54415918	14	+	28162770	OCIAML3	viability	TCAGCTGCTATGGAGGACTTGGG	CDKN3	ENSG00000100526	1.1683297435503546	[92]	[630]	8	hSpCas9	negative selection	12332725
54415909	54415932	14	+	28162770	OCIAML3	viability	GGACTTGGGAGATCTTGTCTTGG	CDKN3	ENSG00000100526	0.3478894051122686	[37]	[145]	3	hSpCas9	negative selection	12332726
54411515	54411538	14	+	28162770	OCIAML3	viability	ATTTGTTTTCTGCACCAGAGGGG	CDKN3	ENSG00000100526	1.0301761701947116	[126]	[782]	8	hSpCas9	negative selection	12332727