Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1048
• Symbol:CEACAM5
• Description:CEA cell adhesion molecule 5

DataSource: http://genomecrispr.dkfz.de/#!/results/CEACAM5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41577427	41577450	19	+	26472758	Jiyoye	viability	CGAGAGACAATATCACCCAGTGG	CEACAM5	ENSG00000105388	1.8646481471051137	[133]	[367]	8	hSpCas9	negative selection	29440
41579367	41579390	19	-	26472758	Jiyoye	viability	GTGCTGCTGGCTTGGATGGAGGG	CEACAM5	ENSG00000105388	0.7224805341995009	[130]	[162]	5	hSpCas9	negative selection	29443
41577227	41577250	19	-	26472758	Jiyoye	viability	AATAAAGAGCCAGGCAGTGGTGG	CEACAM5	ENSG00000105388	0.022834679449945883	[247]	[189]	0	hSpCas9	negative selection	29444
41577333	41577356	19	+	26472758	Jiyoye	viability	CTGGTACAAAGGGAAAACGGTGG	CEACAM5	ENSG00000105388	0.4071753815058732	[32]	[32]	3	hSpCas9	negative selection	29446
41579537	41579560	19	+	26472758	Jiyoye	viability	CATCAGGCAGGAGGACGCTGGGG	CEACAM5	ENSG00000105388	1.7994928042846339	[39]	[104]	8	hSpCas9	negative selection	29448
41579410	41579433	19	-	26472758	Jiyoye	viability	TGTGTGGCAGGTCAGGACCACGG	CEACAM5	ENSG00000105388	-0.9453410332149119	[142]	[55]	-6	hSpCas9	negative selection	29450
41579437	41579460	19	+	26472758	Jiyoye	viability	ACACTGGAACCTCTTTCCAGTGG	CEACAM5	ENSG00000105388	0.7713317117825331	[100]	[129]	5	hSpCas9	negative selection	29452
41577256	41577279	19	+	26472758	Jiyoye	viability	GCGCCCTTTGAAGTTGCTGAAGG	CEACAM5	ENSG00000105388	-0.1688539944452749	[160]	[107]	-1	hSpCas9	negative selection	29454
41577279	41577302	19	+	26472758	Jiyoye	viability	GGAGAATGTTCATCTCTCTGTGG	CEACAM5	ENSG00000105388	0.2989224908538501	[165]	[153]	2	hSpCas9	negative selection	29457
41577403	41577426	19	+	26472758	Jiyoye	viability	ACTCCAGGGCCTGCATACAGCGG	CEACAM5	ENSG00000105388	-0.934744188568955	[108]	[42]	-6	hSpCas9	negative selection	29459
41577427	41577450	19	+	26472758	KBM7	viability	CGAGAGACAATATCACCCAGTGG	CEACAM5	ENSG00000105388	0.010247484768823867	[1355,754]	[483,490]	0	hSpCas9	negative selection	220558
41579367	41579390	19	-	26472758	KBM7	viability	GTGCTGCTGGCTTGGATGGAGGG	CEACAM5	ENSG00000105388	0.2602402030963993	[1046,810]	[652,398]	2	hSpCas9	negative selection	220561
41577227	41577250	19	-	26472758	KBM7	viability	AATAAAGAGCCAGGCAGTGGTGG	CEACAM5	ENSG00000105388	-0.10607229676189439	[732,594]	[412,176]	-1	hSpCas9	negative selection	220562
41577333	41577356	19	+	26472758	KBM7	viability	CTGGTACAAAGGGAAAACGGTGG	CEACAM5	ENSG00000105388	1.0772891418571682	[251,198]	[266,181]	9	hSpCas9	negative selection	220564
41579537	41579560	19	+	26472758	KBM7	viability	CATCAGGCAGGAGGACGCTGGGG	CEACAM5	ENSG00000105388	0.6991086820011919	[591,409]	[382,371]	7	hSpCas9	negative selection	220566
41579410	41579433	19	-	26472758	KBM7	viability	TGTGTGGCAGGTCAGGACCACGG	CEACAM5	ENSG00000105388	-0.7101548601602903	[1007,803]	[368,159]	-5	hSpCas9	negative selection	220568
41579437	41579460	19	+	26472758	KBM7	viability	ACACTGGAACCTCTTTCCAGTGG	CEACAM5	ENSG00000105388	0.49766453222598966	[588,510]	[349,376]	5	hSpCas9	negative selection	220570
41577256	41577279	19	+	26472758	KBM7	viability	GCGCCCTTTGAAGTTGCTGAAGG	CEACAM5	ENSG00000105388	0.15456350941129918	[437,512]	[278,227]	1	hSpCas9	negative selection	220572
41577279	41577302	19	+	26472758	KBM7	viability	GGAGAATGTTCATCTCTCTGTGG	CEACAM5	ENSG00000105388	0.06513806467439448	[706,518]	[311,285]	0	hSpCas9	negative selection	220575
41577403	41577426	19	+	26472758	KBM7	viability	ACTCCAGGGCCTGCATACAGCGG	CEACAM5	ENSG00000105388	-0.7294936052941347	[204,281]	[60,78]	-6	hSpCas9	negative selection	220577
41577427	41577450	19	+	26472758	Raji	viability	CGAGAGACAATATCACCCAGTGG	CEACAM5	ENSG00000105388	1.1829345683807764	[464]	[244]	9	hSpCas9	negative selection	411676
41579367	41579390	19	-	26472758	Raji	viability	GTGCTGCTGGCTTGGATGGAGGG	CEACAM5	ENSG00000105388	-0.45158375681461216	[494]	[83]	-4	hSpCas9	negative selection	411679
41577227	41577250	19	-	26472758	Raji	viability	AATAAAGAGCCAGGCAGTGGTGG	CEACAM5	ENSG00000105388	-0.09852076317427938	[405]	[87]	-1	hSpCas9	negative selection	411680
41577333	41577356	19	+	26472758	Raji	viability	CTGGTACAAAGGGAAAACGGTGG	CEACAM5	ENSG00000105388	0.8414894754005651	[100]	[41]	7	hSpCas9	negative selection	411682
41579537	41579560	19	+	26472758	Raji	viability	CATCAGGCAGGAGGACGCTGGGG	CEACAM5	ENSG00000105388	-0.5978731990652687	[299]	[45]	-5	hSpCas9	negative selection	411684
41579410	41579433	19	-	26472758	Raji	viability	TGTGTGGCAGGTCAGGACCACGG	CEACAM5	ENSG00000105388	-1.4823799516113778	[300]	[24]	-8	hSpCas9	negative selection	411686
41579437	41579460	19	+	26472758	Raji	viability	ACACTGGAACCTCTTTCCAGTGG	CEACAM5	ENSG00000105388	-0.5275041906792388	[440]	[70]	-4	hSpCas9	negative selection	411688
41577256	41577279	19	+	26472758	Raji	viability	GCGCCCTTTGAAGTTGCTGAAGG	CEACAM5	ENSG00000105388	0.21661260512835775	[177]	[47]	2	hSpCas9	negative selection	411690
41577279	41577302	19	+	26472758	Raji	viability	GGAGAATGTTCATCTCTCTGTGG	CEACAM5	ENSG00000105388	-0.04873566654368233	[311]	[69]	0	hSpCas9	negative selection	411693
41577403	41577426	19	+	26472758	Raji	viability	ACTCCAGGGCCTGCATACAGCGG	CEACAM5	ENSG00000105388	-0.8510373608750008	[170]	[21]	-6	hSpCas9	negative selection	411695
41577427	41577450	19	+	26472758	K562	viability	CGAGAGACAATATCACCCAGTGG	CEACAM5	ENSG00000105388	0.34099198736149994	[779]	[833]	2	hSpCas9	negative selection	602794
41579367	41579390	19	-	26472758	K562	viability	GTGCTGCTGGCTTGGATGGAGGG	CEACAM5	ENSG00000105388	-0.2877034488542187	[897]	[620]	-2	hSpCas9	negative selection	602797
41577227	41577250	19	-	26472758	K562	viability	AATAAAGAGCCAGGCAGTGGTGG	CEACAM5	ENSG00000105388	0.42542169283404896	[590]	[669]	3	hSpCas9	negative selection	602798
41577333	41577356	19	+	26472758	K562	viability	CTGGTACAAAGGGAAAACGGTGG	CEACAM5	ENSG00000105388	1.2775855916016463	[128]	[263]	9	hSpCas9	negative selection	602800
41579537	41579560	19	+	26472758	K562	viability	CATCAGGCAGGAGGACGCTGGGG	CEACAM5	ENSG00000105388	0.13548435611328294	[329]	[305]	1	hSpCas9	negative selection	602802
41579410	41579433	19	-	26472758	K562	viability	TGTGTGGCAGGTCAGGACCACGG	CEACAM5	ENSG00000105388	-1.8477887104306419	[532]	[124]	-7	hSpCas9	negative selection	602804
41579437	41579460	19	+	26472758	K562	viability	ACACTGGAACCTCTTTCCAGTGG	CEACAM5	ENSG00000105388	0.35556569158764983	[461]	[498]	2	hSpCas9	negative selection	602806
41577256	41577279	19	+	26472758	K562	viability	GCGCCCTTTGAAGTTGCTGAAGG	CEACAM5	ENSG00000105388	1.1025207593342878	[410]	[744]	8	hSpCas9	negative selection	602808
41577279	41577302	19	+	26472758	K562	viability	GGAGAATGTTCATCTCTCTGTGG	CEACAM5	ENSG00000105388	0.4799068066145781	[422]	[497]	4	hSpCas9	negative selection	602811
41577403	41577426	19	+	26472758	K562	viability	ACTCCAGGGCCTGCATACAGCGG	CEACAM5	ENSG00000105388	-1.0920089369160306	[249]	[98]	-5	hSpCas9	negative selection	602813
41583784	41583807	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATTCAAGGTGAGATTTGGGTGG	CEACAM5	ENSG00000105388	-1.1941293690322994	[67,141]	[3,15]	-7	dCas9-VP64	positive selection	2403168
41598329	41598352	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTGGCGG	CEACAM5	ENSG00000105388	-0.7800023955638035	[210,54]	[8,23]	-4	dCas9-VP64	positive selection	2414253
41627181	41627204	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAAGAGAAAGGGGAAGGAGGG	CEACAM5	ENSG00000105388	1.4007114066694855	[26,23]	[2,27]	5	dCas9-VP64	positive selection	2428668
41627220	41627243	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTAACCACACTTTGAGAAGCAGG	CEACAM5	ENSG00000105388	0.7412296361068171	[59,4]	[19,2]	3	dCas9-VP64	positive selection	2428669
41627249	41627272	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCCCCTGTCCCCAGAGAGG	CEACAM5	ENSG00000105388	0.7971406400401859	[49,145]	[9,66]	3	dCas9-VP64	positive selection	2428670
41708451	41708474	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATCTTTTCGGCAAGGTGGATGG	CEACAM5	ENSG00000105388	-1.674655227998451	[54,167]	[4,8]	-8	dCas9-VP64	positive selection	2435542
41708477	41708500	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGAGGAACTGAAAATAGAAGGG	CEACAM5	ENSG00000105388	-1.1300776737212406	[147,101]	[12,10]	-6	dCas9-VP64	positive selection	2435543
41708427	41708450	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTGTCCTCCCAGGGGATGGGGG	CEACAM5	ENSG00000105388	1.4931653355732828	[11,8]	[8,2]	5	dCas9-VP64	positive selection	2435544
41583784	41583807	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATTCAAGGTGAGATTTGGGTGG	CEACAM5	ENSG00000105388	5.791306622661524	[139,96]	[4450,17]	9	dCas9-VP64	positive selection	2498423
41598329	41598352	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTGGCGG	CEACAM5	ENSG00000105388	7.182660032259671	[52,50]	[5183,10]	9	dCas9-VP64	positive selection	2509508
41627181	41627204	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAAGAGAAAGGGGAAGGAGGG	CEACAM5	ENSG00000105388	-0.4996929941602293	[154,69]	[49,2]	-5	dCas9-VP64	positive selection	2523923
41627220	41627243	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTAACCACACTTTGAGAAGCAGG	CEACAM5	ENSG00000105388	8.411060587376028	[16,29]	[5540,8]	9	dCas9-VP64	positive selection	2523924
41627249	41627272	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCCCCTGTCCCCAGAGAGG	CEACAM5	ENSG00000105388	0.9053031879809783	[101,203]	[47,134]	6	dCas9-VP64	positive selection	2523925
41708451	41708474	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATCTTTTCGGCAAGGTGGATGG	CEACAM5	ENSG00000105388	2.3074244594513296	[88,266]	[46,509]	8	dCas9-VP64	positive selection	2530797
41708477	41708500	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGAGGAACTGAAAATAGAAGGG	CEACAM5	ENSG00000105388	2.83445831851148	[78,19]	[27,201]	9	dCas9-VP64	positive selection	2530798
41708427	41708450	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTGTCCTCCCAGGGGATGGGGG	CEACAM5	ENSG00000105388	-0.8858312174033113	[174,58]	[33,7]	-8	dCas9-VP64	positive selection	2530799
41577310	41577333	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCGAGAATCTTTACAGCTATGG	CEACAM5	ENSG00000105388	0.11428343733063319	[3]	[3,2]	3	hSpCas9	positive selection	4126846
41577236	41577259	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCTGATGCAATAAAGAGCCAGG	CEACAM5	ENSG00000105388	-0.0757507917296299	[2]	[1,2]	-2	hSpCas9	positive selection	4126848
41579583	41579606	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.01104928252723214	[1]	[1,0]	0	hSpCas9	positive selection	4126849
41579471	41579494	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.0812202422204659	[4]	[3,2]	-2	hSpCas9	positive selection	4126850
41577310	41577333	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCGAGAATCTTTACAGCTATGG	CEACAM5	ENSG00000105388	1.4782780786633516	[3]	[5,2,1,4]	9	hSpCas9	positive selection	4190868
41577236	41577259	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCTGATGCAATAAAGAGCCAGG	CEACAM5	ENSG00000105388	1.0737122831101935	[4]	[3,2,4,3]	7	hSpCas9	positive selection	4190870
41579583	41579606	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.3790015910175798	[1]	[0,2,0,0]	3	hSpCas9	positive selection	4190871
41579471	41579494	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.9320784222059455	[5]	[4,4,2,4]	6	hSpCas9	positive selection	4190872
41577363	41577386	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.07355661959041579	[2]	[2,1]	-1	hSpCas9	positive selection	4262632
41585445	41585468	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.46601427006854257	[3]	[3,4]	8	hSpCas9	positive selection	4262633
41579471	41579494	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.2769723240044969	[3]	[3,3]	5	hSpCas9	positive selection	4262634
41577543	41577566	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.46234555475424216	[2]	[1,0]	-7	hSpCas9	positive selection	4326909
41579583	41579606	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.26907299307863364	[1]	[0,0]	-5	hSpCas9	positive selection	4326910
41585445	41585468	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.2743722614344526	[2]	[2,0]	-5	hSpCas9	positive selection	4326911
41577363	41577386	19	-	27260156	BXPC3	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.06564736992855791	[336]	[348,310,388,437]	1	hSpCas9	negative selection	5535092
41585445	41585468	19	-	27260156	BXPC3	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.031642511859752975	[738]	[716,610,766,961]	0	hSpCas9	negative selection	5535093
41579471	41579494	19	-	27260156	BXPC3	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.08762791538052428	[785]	[849,776,810,1081]	2	hSpCas9	negative selection	5535094
41577543	41577566	19	-	27260156	BXPC3	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.6025856213134618	[267]	[145,159,201,241]	-8	hSpCas9	negative selection	5599369
41579583	41579606	19	-	27260156	BXPC3	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.09504745977602469	[118]	[111,96,118,141]	-2	hSpCas9	negative selection	5599370
41585445	41585468	19	+	27260156	BXPC3	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.0835300015471736	[330]	[256,247,457,359]	-2	hSpCas9	negative selection	5599371
41577363	41577386	19	-	27260156	A673	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.09295414869476959	[336]	[360,386,261,512]	-2	hSpCas9	negative selection	5656343
41585445	41585468	19	-	27260156	A673	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.13085176467456838	[738]	[1135,937,877,951]	3	hSpCas9	negative selection	5656344
41579471	41579494	19	-	27260156	A673	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.03072597989178416	[785]	[992,990,852,859]	0	hSpCas9	negative selection	5656345
41577543	41577566	19	-	27260156	A673	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.47917324565105524	[267]	[309,225,162,233]	-8	hSpCas9	negative selection	5720620
41579583	41579606	19	-	27260156	A673	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.1315922558252931	[118]	[135,117,113,155]	-3	hSpCas9	negative selection	5720621
41585445	41585468	19	+	27260156	A673	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.15088056577149533	[330]	[453,298,391,294]	-4	hSpCas9	negative selection	5720622
41577363	41577386	19	-	27260156	A375	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.221138418252731	[336]	[336,521,473,502]	3	hSpCas9	negative selection	5777594
41585445	41585468	19	-	27260156	A375	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.12059208298390978	[738]	[1094,1036,788,853]	1	hSpCas9	negative selection	5777595
41579471	41579494	19	-	27260156	A375	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.12213379786012757	[785]	[764,905,929,784]	-2	hSpCas9	negative selection	5777596
41577543	41577566	19	-	27260156	A375	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.8000427541347112	[267]	[238,155,181,142]	-7	hSpCas9	negative selection	5841871
41579583	41579606	19	-	27260156	A375	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.2823148531381052	[118]	[225,262,132,77]	4	hSpCas9	negative selection	5841872
41585445	41585468	19	+	27260156	A375	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.23259031334470764	[330]	[525,328,587,365]	3	hSpCas9	negative selection	5841873
41577363	41577386	19	-	27260156	COLO741	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.16834664639198144	[336]	[536,392,521]	3	hSpCas9	negative selection	5898845
41585445	41585468	19	-	27260156	COLO741	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.10791618439513184	[738]	[993,970,685]	-2	hSpCas9	negative selection	5898846
41579471	41579494	19	-	27260156	COLO741	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.10561220632769452	[785]	[1179,1091,982]	2	hSpCas9	negative selection	5898847
41577543	41577566	19	-	27260156	COLO741	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.7384714575999475	[267]	[236,218,164]	-9	hSpCas9	negative selection	5963122
41579583	41579606	19	-	27260156	COLO741	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.06093434257131003	[118]	[195,157,126]	1	hSpCas9	negative selection	5963123
41585445	41585468	19	+	27260156	COLO741	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.09057638883948826	[330]	[372,581,392]	2	hSpCas9	negative selection	5963124
41577363	41577386	19	-	27260156	CAL120	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.4400691361176444	[336]	[355,254,322]	-6	hSpCas9	negative selection	6020096
41585445	41585468	19	-	27260156	CAL120	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.16128447078154184	[738]	[1228,919,966]	2	hSpCas9	negative selection	6020097
41579471	41579494	19	-	27260156	CAL120	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.21749989954630633	[785]	[1136,1236,1038]	3	hSpCas9	negative selection	6020098
41577543	41577566	19	-	27260156	CAL120	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.0269656995404558	[267]	[207,267,484]	0	hSpCas9	negative selection	6084373
41579583	41579606	19	-	27260156	CAL120	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.45646037332066647	[118]	[123,86,114]	-6	hSpCas9	negative selection	6084374
41585445	41585468	19	+	27260156	CAL120	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.5092855680901827	[330]	[216,342,296]	-6	hSpCas9	negative selection	6084375
41577363	41577386	19	-	27260156	CADOES1	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.12017673037783311	[336]	[476,233,362,285]	2	hSpCas9	negative selection	6141347
41585445	41585468	19	-	27260156	CADOES1	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.15959746474308845	[738]	[490,627,692,650]	-3	hSpCas9	negative selection	6141348
41579471	41579494	19	-	27260156	CADOES1	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.00873268192952048	[785]	[781,755,764,634]	0	hSpCas9	negative selection	6141349
41577543	41577566	19	-	27260156	CADOES1	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.17328025438102224	[267]	[202,263,229,185]	-3	hSpCas9	negative selection	6205624
41579583	41579606	19	-	27260156	CADOES1	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.17147425421219764	[118]	[148,136,101,109]	3	hSpCas9	negative selection	6205625
41585445	41585468	19	+	27260156	CADOES1	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.14389648503891528	[330]	[299,213,252,349]	-2	hSpCas9	negative selection	6205626
41577363	41577386	19	-	27260156	EWS502	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.4664712910998057	[336]	[492,388,386,720]	7	hSpCas9	negative selection	6262598
41585445	41585468	19	-	27260156	EWS502	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.16287625446113807	[738]	[866,938,888,799]	3	hSpCas9	negative selection	6262599
41579471	41579494	19	-	27260156	EWS502	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.006077053268069621	[785]	[712,710,780,1148]	0	hSpCas9	negative selection	6262600
41577543	41577566	19	-	27260156	EWS502	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.306807654542972	[267]	[153,240,313,216]	-5	hSpCas9	negative selection	6326875
41579583	41579606	19	-	27260156	EWS502	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.3194368989093259	[118]	[127,102,80,86]	-5	hSpCas9	negative selection	6326876
41585445	41585468	19	+	27260156	EWS502	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.14999334579949675	[330]	[336,297,401,217]	-3	hSpCas9	negative selection	6326877
41577363	41577386	19	-	27260156	EW8	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.1376799854885274	[336]	[290,283,268,360]	2	hSpCas9	negative selection	6383849
41585445	41585468	19	-	27260156	EW8	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.19095353761772926	[738]	[582,490,418,627]	-4	hSpCas9	negative selection	6383850
41579471	41579494	19	-	27260156	EW8	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.1347381364909388	[785]	[641,613,551,522]	-3	hSpCas9	negative selection	6383851
41577543	41577566	19	-	27260156	EW8	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.2077597896332094	[267]	[214,198,162,181]	-4	hSpCas9	negative selection	6448126
41579583	41579606	19	-	27260156	EW8	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.5160597257512822	[118]	[82,68,224,152]	8	hSpCas9	negative selection	6448127
41585445	41585468	19	+	27260156	EW8	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.06244744885159431	[330]	[371,297,268,192]	1	hSpCas9	negative selection	6448128
41577363	41577386	19	-	27260156	CORL105	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.011191017843741824	[336]	[378,320,461,438]	0	hSpCas9	negative selection	6505100
41585445	41585468	19	-	27260156	CORL105	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.22143433307369748	[738]	[640,678,835,823]	-4	hSpCas9	negative selection	6505101
41579471	41579494	19	-	27260156	CORL105	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.017694558225212154	[785]	[931,929,908,864]	0	hSpCas9	negative selection	6505102
41577543	41577566	19	-	27260156	CORL105	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.3463336253088424	[267]	[330,282,185,179]	-6	hSpCas9	negative selection	6569377
41579583	41579606	19	-	27260156	CORL105	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.15794353851726428	[118]	[156,113,175,61]	-3	hSpCas9	negative selection	6569378
41585445	41585468	19	+	27260156	CORL105	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.18860668711625916	[330]	[291,426,472,185]	-3	hSpCas9	negative selection	6569379
41577363	41577386	19	-	27260156	HS294T	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.3028879514820311	[336]	[107,163,191,187]	4	hSpCas9	negative selection	6626351
41585445	41585468	19	-	27260156	HS294T	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.3365048583619321	[738]	[369,416,326,317]	4	hSpCas9	negative selection	6626352
41579471	41579494	19	-	27260156	HS294T	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.0007123157887708453	[785]	[270,218,331,416]	0	hSpCas9	negative selection	6626353
41577543	41577566	19	-	27260156	HS294T	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.8262853068182258	[267]	[57,44,67,63]	-8	hSpCas9	negative selection	6690628
41579583	41579606	19	-	27260156	HS294T	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.515703554868638	[118]	[58,34,122,43]	7	hSpCas9	negative selection	6690629
41585445	41585468	19	+	27260156	HS294T	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.04303568619717446	[330]	[137,75,193,117]	0	hSpCas9	negative selection	6690630
41577363	41577386	19	-	27260156	HCC44	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.036359391357845605	[336]	[355,217,496,451]	0	hSpCas9	negative selection	6747602
41585445	41585468	19	-	27260156	HCC44	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.25640797821961236	[738]	[902,755,1471,962]	4	hSpCas9	negative selection	6747603
41579471	41579494	19	-	27260156	HCC44	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.2502734221485374	[785]	[1389,757,1273,913]	4	hSpCas9	negative selection	6747604
41577543	41577566	19	-	27260156	HCC44	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.20535382274464353	[267]	[292,278,290,193]	-3	hSpCas9	negative selection	6811879
41579583	41579606	19	-	27260156	HCC44	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.06634873615132997	[118]	[64,81,221,159]	-1	hSpCas9	negative selection	6811880
41585445	41585468	19	+	27260156	HCC44	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.13862970345595838	[330]	[441,362,337,223]	-2	hSpCas9	negative selection	6811881
41577363	41577386	19	-	27260156	G402	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.7605919788618114	[336]	[489,854,460,944]	8	hSpCas9	negative selection	6868853
41585445	41585468	19	-	27260156	G402	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.3550663799969134	[738]	[1256,1540,770,1080]	4	hSpCas9	negative selection	6868854
41579471	41579494	19	-	27260156	G402	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.17181177024280592	[785]	[462,1303,806,800]	-2	hSpCas9	negative selection	6868855
41577543	41577566	19	-	27260156	G402	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.350399271938994	[267]	[338,322,126,251]	-4	hSpCas9	negative selection	6933130
41579583	41579606	19	-	27260156	G402	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.46970904448806605	[118]	[154,303,208,137]	6	hSpCas9	negative selection	6933131
41585445	41585468	19	+	27260156	G402	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.22122963712790905	[330]	[645,533,292,438]	2	hSpCas9	negative selection	6933132
41577363	41577386	19	-	27260156	L33	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.2215806189597908	[336]	[405,133,230,469]	5	hSpCas9	negative selection	6990104
41585445	41585468	19	-	27260156	L33	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.04312393233259593	[738]	[767,336,493,669]	1	hSpCas9	negative selection	6990105
41579471	41579494	19	-	27260156	L33	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.4914874782492141	[785]	[1172,451,666,1080]	8	hSpCas9	negative selection	6990106
41577543	41577566	19	-	27260156	L33	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.41707137294628815	[267]	[185,87,139,179]	-7	hSpCas9	negative selection	7054381
41579583	41579606	19	-	27260156	L33	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.12845467085769013	[118]	[141,54,56,67]	-3	hSpCas9	negative selection	7054382
41585445	41585468	19	+	27260156	L33	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.5164058335012036	[330]	[230,55,178,272]	-8	hSpCas9	negative selection	7054383
41577363	41577386	19	-	27260156	K562	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.3508303200365229	[336]	[435,224,258,576]	4	hSpCas9	negative selection	7111355
41585445	41585468	19	-	27260156	K562	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.207241689727109	[738]	[826,1142,472,623]	2	hSpCas9	negative selection	7111356
41579471	41579494	19	-	27260156	K562	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.02688034795683336	[785]	[1048,665,397,654]	0	hSpCas9	negative selection	7111357
41577543	41577566	19	-	27260156	K562	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.15775546660212647	[267]	[363,159,223,123]	-2	hSpCas9	negative selection	7175632
41579583	41579606	19	-	27260156	K562	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	1.4468608798677163	[118]	[396,297,225,243]	9	hSpCas9	negative selection	7175633
41585445	41585468	19	+	27260156	K562	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.32966538234086684	[330]	[141,230,231,311]	-4	hSpCas9	negative selection	7175634
41577363	41577386	19	-	27260156	HT29	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.1542142832012104	[336]	[489,364,530,431]	3	hSpCas9	negative selection	7232606
41585445	41585468	19	-	27260156	HT29	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.06758724809639438	[738]	[897,864,918,756]	-1	hSpCas9	negative selection	7232607
41579471	41579494	19	-	27260156	HT29	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.20826744028403887	[785]	[831,845,860,771]	-4	hSpCas9	negative selection	7232608
41577543	41577566	19	-	27260156	HT29	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.705717750490715	[267]	[168,331,127,179]	-8	hSpCas9	negative selection	7296883
41579583	41579606	19	-	27260156	HT29	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.045161432484265296	[118]	[87,178,168,124]	-1	hSpCas9	negative selection	7296884
41585445	41585468	19	+	27260156	HT29	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.23914430697009037	[330]	[342,398,262,358]	-5	hSpCas9	negative selection	7296885
41577363	41577386	19	-	27260156	MHHES1	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.3167503066506311	[336]	[428,686,451,355]	6	hSpCas9	negative selection	7353857
41585445	41585468	19	-	27260156	MHHES1	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.09470207171996481	[738]	[906,910,768,586]	-2	hSpCas9	negative selection	7353858
41579471	41579494	19	-	27260156	MHHES1	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.15015502993873553	[785]	[1019,1261,787,889]	2	hSpCas9	negative selection	7353859
41577543	41577566	19	-	27260156	MHHES1	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.2858853535789435	[267]	[383,290,155,187]	-5	hSpCas9	negative selection	7418134
41579583	41579606	19	-	27260156	MHHES1	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.302927785486105	[118]	[168,168,178,145]	5	hSpCas9	negative selection	7418135
41585445	41585468	19	+	27260156	MHHES1	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.11318194499017897	[330]	[479,439,384,328]	2	hSpCas9	negative selection	7418136
41577363	41577386	19	-	27260156	MEWO	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.20070252385624254	[336]	[262,223,333]	-4	hSpCas9	negative selection	7475108
41585445	41585468	19	-	27260156	MEWO	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.044055772650844705	[738]	[814,526,816]	1	hSpCas9	negative selection	7475109
41579471	41579494	19	-	27260156	MEWO	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.025472834923198184	[785]	[720,721,723]	0	hSpCas9	negative selection	7475110
41577543	41577566	19	-	27260156	MEWO	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.524272827252387	[267]	[241,189,103]	-8	hSpCas9	negative selection	7539385
41579583	41579606	19	-	27260156	MEWO	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.3046866267481685	[118]	[226,104,97]	6	hSpCas9	negative selection	7539386
41585445	41585468	19	+	27260156	MEWO	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.016474106257541365	[330]	[452,249,263]	0	hSpCas9	negative selection	7539387
41577363	41577386	19	-	27260156	LNCAPCLONEFGC	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.05270764017032148	[336]	[265,193,278,442]	-1	hSpCas9	negative selection	7596359
41585445	41585468	19	-	27260156	LNCAPCLONEFGC	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.14198447859114005	[738]	[716,642,853,763]	2	hSpCas9	negative selection	7596360
41579471	41579494	19	-	27260156	LNCAPCLONEFGC	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.15585409256649807	[785]	[719,923,798,722]	2	hSpCas9	negative selection	7596361
41577543	41577566	19	-	27260156	LNCAPCLONEFGC	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.21629792190797403	[267]	[288,139,203,204]	-3	hSpCas9	negative selection	7660636
41579583	41579606	19	-	27260156	LNCAPCLONEFGC	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.5260701770674796	[118]	[185,95,86,244]	8	hSpCas9	negative selection	7660637
41585445	41585468	19	+	27260156	LNCAPCLONEFGC	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.10302669688019295	[330]	[233,312,333,410]	1	hSpCas9	negative selection	7660638
41577363	41577386	19	-	27260156	PANC0327	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.3874533922541653	[336]	[324,775,224,184]	6	hSpCas9	negative selection	7717610
41585445	41585468	19	-	27260156	PANC0327	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.2583331291050902	[738]	[603,641,815,1081]	4	hSpCas9	negative selection	7717611
41579471	41579494	19	-	27260156	PANC0327	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.21286618408244762	[785]	[617,482,536,787]	-3	hSpCas9	negative selection	7717612
41577543	41577566	19	-	27260156	PANC0327	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	0.008935068968966675	[267]	[89,300,294,251]	0	hSpCas9	negative selection	7781887
41579583	41579606	19	-	27260156	PANC0327	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.21551926076975714	[118]	[153,56,145,144]	3	hSpCas9	negative selection	7781888
41585445	41585468	19	+	27260156	PANC0327	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.15048648660710362	[330]	[254,322,151,320]	-2	hSpCas9	negative selection	7781889
41577363	41577386	19	-	27260156	NCIH2009	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.47525839161017014	[336]	[816,634,542]	6	hSpCas9	negative selection	7838861
41585445	41585468	19	-	27260156	NCIH2009	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.02856612076913878	[738]	[1157,1128,889]	0	hSpCas9	negative selection	7838862
41579471	41579494	19	-	27260156	NCIH2009	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.4339583003640507	[785]	[1575,1009,1888]	6	hSpCas9	negative selection	7838863
41577543	41577566	19	-	27260156	NCIH2009	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-1.135468978815724	[267]	[194,163,156]	-8	hSpCas9	negative selection	7903138
41579583	41579606	19	-	27260156	NCIH2009	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.3334071900520046	[118]	[301,175,168]	4	hSpCas9	negative selection	7903139
41585445	41585468	19	+	27260156	NCIH2009	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.1975006734894944	[330]	[562,389,287]	-3	hSpCas9	negative selection	7903140
41577363	41577386	19	-	27260156	NCIH1373	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.579193676828244	[336]	[648,398,650,153]	6	hSpCas9	negative selection	7960112
41585445	41585468	19	-	27260156	NCIH1373	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.1385163816207735	[738]	[727,791,1281,212]	1	hSpCas9	negative selection	7960113
41579471	41579494	19	-	27260156	NCIH1373	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.07920214630269884	[785]	[613,1026,969,170]	-1	hSpCas9	negative selection	7960114
41577543	41577566	19	-	27260156	NCIH1373	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.9437201674291061	[267]	[74,30,249,71]	-7	hSpCas9	negative selection	8024389
41579583	41579606	19	-	27260156	NCIH1373	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.16520786838755552	[118]	[102,151,71,37]	-2	hSpCas9	negative selection	8024390
41585445	41585468	19	+	27260156	NCIH1373	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.10316421385635494	[330]	[313,696,364,40]	1	hSpCas9	negative selection	8024391
41577363	41577386	19	-	27260156	PATU8902	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.1831976809202116	[336]	[438,1051,349,309]	1	hSpCas9	negative selection	8081363
41585445	41585468	19	-	27260156	PATU8902	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.6315570850851702	[738]	[1448,1933,1585,1374]	6	hSpCas9	negative selection	8081364
41579471	41579494	19	-	27260156	PATU8902	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.13415053236461139	[785]	[791,1329,804,2082]	1	hSpCas9	negative selection	8081365
41577543	41577566	19	-	27260156	PATU8902	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.3860299193308302	[267]	[119,572,210,254]	-4	hSpCas9	negative selection	8145640
41579583	41579606	19	-	27260156	PATU8902	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.42119073342607827	[118]	[530,206,84,76]	4	hSpCas9	negative selection	8145641
41585445	41585468	19	+	27260156	PATU8902	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.07543440918810496	[330]	[242,659,427,418]	0	hSpCas9	negative selection	8145642
41577363	41577386	19	-	27260156	PANC1	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.31539209097713883	[336]	[413,496,273,287]	5	hSpCas9	negative selection	8202614
41585445	41585468	19	-	27260156	PANC1	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.4924260208497726	[738]	[717,1164,905,836]	7	hSpCas9	negative selection	8202615
41579471	41579494	19	-	27260156	PANC1	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.48413072610152985	[785]	[863,1431,900,705]	7	hSpCas9	negative selection	8202616
41577543	41577566	19	-	27260156	PANC1	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.20477472259288387	[267]	[253,191,170,178]	-3	hSpCas9	negative selection	8266891
41579583	41579606	19	-	27260156	PANC1	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.0777078575980128	[118]	[149,89,117,72]	1	hSpCas9	negative selection	8266892
41585445	41585468	19	+	27260156	PANC1	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.12173579929319489	[330]	[236,218,321,255]	-2	hSpCas9	negative selection	8266893
41577363	41577386	19	-	27260156	PANC0813	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.691379637241353	[336]	[591,668,435,841]	9	hSpCas9	negative selection	8323865
41585445	41585468	19	-	27260156	PANC0813	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.11004178343202775	[738]	[958,1096,754,935]	1	hSpCas9	negative selection	8323866
41579471	41579494	19	-	27260156	PANC0813	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.10841078748896615	[785]	[1080,792,826,749]	-2	hSpCas9	negative selection	8323867
41577543	41577566	19	-	27260156	PANC0813	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.1884961383975129	[267]	[364,155,229,356]	-3	hSpCas9	negative selection	8388142
41579583	41579606	19	-	27260156	PANC0813	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.6340191011335456	[118]	[189,62,75,42]	-7	hSpCas9	negative selection	8388143
41585445	41585468	19	+	27260156	PANC0813	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.14193005118440494	[330]	[478,315,233,388]	-2	hSpCas9	negative selection	8388144
41577363	41577386	19	-	27260156	RDES	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.042876453874677034	[336]	[360,377,315,560]	0	hSpCas9	negative selection	8445116
41585445	41585468	19	-	27260156	RDES	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.06786120654773353	[738]	[774,862,951,989]	1	hSpCas9	negative selection	8445117
41579471	41579494	19	-	27260156	RDES	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.007733864285159986	[785]	[730,908,905,1086]	0	hSpCas9	negative selection	8445118
41577543	41577566	19	-	27260156	RDES	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.614559215833809	[267]	[126,175,178,359]	-8	hSpCas9	negative selection	8509393
41579583	41579606	19	-	27260156	RDES	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.5763416871223397	[118]	[167,245,267,120]	8	hSpCas9	negative selection	8509394
41585445	41585468	19	+	27260156	RDES	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.05021124750399253	[330]	[229,380,418,477]	-1	hSpCas9	negative selection	8509395
41577363	41577386	19	-	27260156	PC3	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.06697293346658273	[336]	[281,313,506,354]	1	hSpCas9	negative selection	8566367
41585445	41585468	19	-	27260156	PC3	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.07490425256943178	[738]	[506,638,1445,822]	1	hSpCas9	negative selection	8566368
41579471	41579494	19	-	27260156	PC3	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.1458341772972308	[785]	[514,724,1814,864]	3	hSpCas9	negative selection	8566369
41577543	41577566	19	-	27260156	PC3	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.14335891267599987	[267]	[181,163,271,369]	-3	hSpCas9	negative selection	8630644
41579583	41579606	19	-	27260156	PC3	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.09393018373112083	[118]	[54,167,158,157]	2	hSpCas9	negative selection	8630645
41585445	41585468	19	+	27260156	PC3	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.01972623954164876	[330]	[195,331,512,360]	0	hSpCas9	negative selection	8630646
41577363	41577386	19	-	27260156	PATU8988T	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.023199163923829702	[336]	[325,439,290,228]	0	hSpCas9	negative selection	8687618
41585445	41585468	19	-	27260156	PATU8988T	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	-0.2738834840673125	[738]	[464,782,366,783]	-4	hSpCas9	negative selection	8687619
41579471	41579494	19	-	27260156	PATU8988T	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.3521984886200812	[785]	[1076,790,1173,802]	6	hSpCas9	negative selection	8687620
41577543	41577566	19	-	27260156	PATU8988T	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.46039266006918445	[267]	[155,165,200,230]	-6	hSpCas9	negative selection	8751895
41579583	41579606	19	-	27260156	PATU8988T	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.6511590350187604	[118]	[44,90,78,79]	-7	hSpCas9	negative selection	8751896
41585445	41585468	19	+	27260156	PATU8988T	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.21345221096231326	[330]	[483,162,222,218]	-4	hSpCas9	negative selection	8751897
41577363	41577386	19	-	27260156	T47D	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.041922959651479075	[336]	[397,377,324,426]	-1	hSpCas9	negative selection	8808869
41585445	41585468	19	-	27260156	T47D	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.1898281632650729	[738]	[1043,913,1026,946]	4	hSpCas9	negative selection	8808870
41579471	41579494	19	-	27260156	T47D	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.012799303372736826	[785]	[924,910,975,881]	0	hSpCas9	negative selection	8808871
41577543	41577566	19	-	27260156	T47D	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.39350944757828554	[267]	[240,210,213,288]	-7	hSpCas9	negative selection	8873146
41579583	41579606	19	-	27260156	T47D	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.00024340585771831513	[118]	[133,171,146,96]	0	hSpCas9	negative selection	8873147
41585445	41585468	19	+	27260156	T47D	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.08051222636523159	[330]	[428,329,364,336]	-2	hSpCas9	negative selection	8873148
41577363	41577386	19	-	27260156	SU8686	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.178472181324891	[336]	[392,375,401,329]	3	hSpCas9	negative selection	8930120
41585445	41585468	19	-	27260156	SU8686	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.003116325018310717	[738]	[601,582,877,940]	0	hSpCas9	negative selection	8930121
41579471	41579494	19	-	27260156	SU8686	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.4166076381940672	[785]	[990,980,885,1354]	7	hSpCas9	negative selection	8930122
41577543	41577566	19	-	27260156	SU8686	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.6954577618753454	[267]	[115,173,202,167]	-7	hSpCas9	negative selection	8994397
41579583	41579606	19	-	27260156	SU8686	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.5967660415871439	[118]	[214,113,187,203]	8	hSpCas9	negative selection	8994398
41585445	41585468	19	+	27260156	SU8686	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	0.053347477660162845	[330]	[266,340,347,425]	0	hSpCas9	negative selection	8994399
41577363	41577386	19	-	27260156	SKES1	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.18138469003993246	[336]	[446,529,354,233]	4	hSpCas9	negative selection	9051371
41585445	41585468	19	-	27260156	SKES1	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.08743721590367814	[738]	[990,773,692,704]	2	hSpCas9	negative selection	9051372
41579471	41579494	19	-	27260156	SKES1	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.05343748551516425	[785]	[865,863,765,568]	-1	hSpCas9	negative selection	9051373
41577543	41577566	19	-	27260156	SKES1	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.19693187267179757	[267]	[290,272,163,217]	-4	hSpCas9	negative selection	9115648
41579583	41579606	19	-	27260156	SKES1	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.011621977829778585	[118]	[90,167,126,95]	0	hSpCas9	negative selection	9115649
41585445	41585468	19	+	27260156	SKES1	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.2876897796649237	[330]	[262,371,316,151]	-6	hSpCas9	negative selection	9115650
41577363	41577386	19	-	27260156	TOV112D	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.1358759876452309	[336]	[153,699,186,271]	-3	hSpCas9	negative selection	9172622
41585445	41585468	19	-	27260156	TOV112D	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.3009037088648454	[738]	[1043,1038,942,668]	6	hSpCas9	negative selection	9172623
41579471	41579494	19	-	27260156	TOV112D	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.3288733779736622	[785]	[634,943,569,440]	-6	hSpCas9	negative selection	9172624
41577543	41577566	19	-	27260156	TOV112D	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.593735456097216	[267]	[156,255,187,128]	-8	hSpCas9	negative selection	9236899
41579583	41579606	19	-	27260156	TOV112D	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.2370313099772281	[118]	[141,213,160,64]	4	hSpCas9	negative selection	9236900
41585445	41585468	19	+	27260156	TOV112D	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.24105395779098782	[330]	[108,355,282,374]	-5	hSpCas9	negative selection	9236901
41577363	41577386	19	-	27260156	TC71	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	-0.30157004048082037	[336]	[269,365,249,287]	-7	hSpCas9	negative selection	9293873
41585445	41585468	19	-	27260156	TC71	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.08790113878392791	[738]	[805,766,938,853]	2	hSpCas9	negative selection	9293874
41579471	41579494	19	-	27260156	TC71	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	-0.006351948766203486	[785]	[639,792,948,982]	0	hSpCas9	negative selection	9293875
41577543	41577566	19	-	27260156	TC71	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.01396099029503517	[267]	[277,346,219,295]	0	hSpCas9	negative selection	9358150
41579583	41579606	19	-	27260156	TC71	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	-0.1048474737897076	[118]	[66,176,140,87]	-3	hSpCas9	negative selection	9358151
41585445	41585468	19	+	27260156	TC71	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.29706857876012316	[330]	[280,296,191,394]	-7	hSpCas9	negative selection	9358152
41577363	41577386	19	-	27260156	TC32	viability	TTACATATGCTGCGATTAGCTGG	CEACAM5	ENSG00000105388	0.026207912084495966	[336]	[413,150,349,419]	0	hSpCas9	negative selection	9415124
41585445	41585468	19	-	27260156	TC32	viability	CCTGAAGTCACTCTGATCGCTGG	CEACAM5	ENSG00000105388	0.12894430766859255	[738]	[614,584,1104,836]	2	hSpCas9	negative selection	9415125
41579471	41579494	19	-	27260156	TC32	viability	TCTTCGTGACCTGCAGACGCTGG	CEACAM5	ENSG00000105388	0.16267707062128123	[785]	[642,550,1399,898]	3	hSpCas9	negative selection	9415126
41577543	41577566	19	-	27260156	TC32	viability	ACTCACCGTATACACGGAGATGG	CEACAM5	ENSG00000105388	-0.5257995746555021	[267]	[188,161,169,168]	-7	hSpCas9	negative selection	9479401
41579583	41579606	19	-	27260156	TC32	viability	TCGCTCCTGTTGGAGCTGACTGG	CEACAM5	ENSG00000105388	0.41429550503827417	[118]	[78,72,234,260]	7	hSpCas9	negative selection	9479402
41585445	41585468	19	+	27260156	TC32	viability	CCAGCGATCAGAGTGACTTCAGG	CEACAM5	ENSG00000105388	-0.020713331124967316	[330]	[262,181,509,344]	0	hSpCas9	negative selection	9479403