| 41755657 | 41755680 | 19 | - | 26472758 | Jiyoye | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | 0.43271047361301085 | [55] | [56] | 3 | hSpCas9 | negative selection | 29490 | 41755677 | 41755700 | 19 | - | 26472758 | Jiyoye | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.026334777844449153 | [523] | [387] | 0 | hSpCas9 | negative selection | 29491 | 41756622 | 41756645 | 19 | - | 26472758 | Jiyoye | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.4739241993604595 | [358] | [375] | 3 | hSpCas9 | negative selection | 29492 | 41756700 | 41756723 | 19 | - | 26472758 | Jiyoye | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.28518485712726305 | [36] | [33] | 2 | hSpCas9 | negative selection | 29493 | 41756733 | 41756756 | 19 | + | 26472758 | Jiyoye | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 1.8620773416626566 | [57] | [158] | 8 | hSpCas9 | negative selection | 29494 | 41755657 | 41755680 | 19 | - | 26472758 | KBM7 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.179432851746253 | [322,204] | [104,109] | -2 | hSpCas9 | negative selection | 220608 | 41755677 | 41755700 | 19 | - | 26472758 | KBM7 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.19355058908528866 | [2173,1573] | [692,822] | -2 | hSpCas9 | negative selection | 220609 | 41756622 | 41756645 | 19 | - | 26472758 | KBM7 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.9637908406366071 | [1737,1318] | [1673,1133] | 9 | hSpCas9 | negative selection | 220610 | 41756700 | 41756723 | 19 | - | 26472758 | KBM7 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | -0.511675401559202 | [230,136] | [51,65] | -4 | hSpCas9 | negative selection | 220611 | 41756733 | 41756756 | 19 | + | 26472758 | KBM7 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.13135417863817456 | [752,690] | [503,253] | 1 | hSpCas9 | negative selection | 220612 | 41755657 | 41755680 | 19 | - | 26472758 | Raji | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.563154697053631 | [190] | [29] | -4 | hSpCas9 | negative selection | 411726 | 41755677 | 41755700 | 19 | - | 26472758 | Raji | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | 0.018116197276512036 | [799] | [187] | 0 | hSpCas9 | negative selection | 411727 | 41756622 | 41756645 | 19 | - | 26472758 | Raji | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.2775445991646164 | [678] | [190] | 2 | hSpCas9 | negative selection | 411728 | 41756700 | 41756723 | 19 | - | 26472758 | Raji | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 2.1073835353735992 | [28] | [28] | 9 | hSpCas9 | negative selection | 411729 | 41756733 | 41756756 | 19 | + | 26472758 | Raji | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.710660933474838 | [286] | [108] | 6 | hSpCas9 | negative selection | 411730 | 41755657 | 41755680 | 19 | - | 26472758 | K562 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.18816697282324402 | [192] | [142] | -1 | hSpCas9 | negative selection | 602844 | 41755677 | 41755700 | 19 | - | 26472758 | K562 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | 0.07420903060586692 | [1266] | [1125] | 0 | hSpCas9 | negative selection | 602845 | 41756622 | 41756645 | 19 | - | 26472758 | K562 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.6704872640695836 | [1367] | [1837] | 5 | hSpCas9 | negative selection | 602846 | 41756700 | 41756723 | 19 | - | 26472758 | K562 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 1.0176478658194248 | [164] | [281] | 8 | hSpCas9 | negative selection | 602847 | 41756733 | 41756756 | 19 | + | 26472758 | K562 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.5856645198381881 | [726] | [920] | 5 | hSpCas9 | negative selection | 602848 | 41755396 | 41755419 | 19 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACAGAAAGGGAAGAGGAGGAGGG | CEACAM6 | ENSG00000086548 | -0.5892115815378526 | [19,209] | [17,15] | -3 | dCas9-VP64 | positive selection | 2430504 | 41755361 | 41755384 | 19 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCTTCTCAGAGCATCTTCTGGGG | CEACAM6 | ENSG00000086548 | 3.081438561677653 | [57,39] | [166,8] | 8 | dCas9-VP64 | positive selection | 2430505 | 41755330 | 41755353 | 19 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTGGACCCCTGTTCCATAACAGG | CEACAM6 | ENSG00000086548 | 2.7648111174156837 | [203,856] | [25,1640] | 8 | dCas9-VP64 | positive selection | 2430506 | 41755396 | 41755419 | 19 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACAGAAAGGGAAGAGGAGGAGGG | CEACAM6 | ENSG00000086548 | -0.19589662629201077 | [90,54] | [22,17] | -2 | dCas9-VP64 | positive selection | 2525759 | 41755361 | 41755384 | 19 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCTTCTCAGAGCATCTTCTGGGG | CEACAM6 | ENSG00000086548 | 0.7341736961206571 | [105,23] | [36,32] | 5 | dCas9-VP64 | positive selection | 2525760 | 41755330 | 41755353 | 19 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTGGACCCCTGTTCCATAACAGG | CEACAM6 | ENSG00000086548 | -0.8556598105828218 | [159,338] | [35,52] | -7 | dCas9-VP64 | positive selection | 2525761 | 41755661 | 41755684 | 19 | + | 27260157 | DLD1 | viability | CCTGCAGATTGCATGTCCCCTGG | CEACAM6 | ENSG00000086548 | -0.29064138552196 | [] | [] | -2 | hSpCas9 | negative selection | 2577478 | 41755655 | 41755678 | 19 | - | 27260157 | DLD1 | viability | GACATGCAATCTGCAGGGAGGGG | CEACAM6 | ENSG00000086548 | -0.266769313248857 | [] | [] | -2 | hSpCas9 | negative selection | 2605824 | 41756714 | 41756737 | 19 | + | 27260157 | DLD1 | viability | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 0.251064188732835 | [] | [] | 4 | hSpCas9 | negative selection | 2607958 | 41756704 | 41756727 | 19 | + | 27260157 | DLD1 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.353460700213299 | [] | [] | -3 | hSpCas9 | negative selection | 2613550 | 41755661 | 41755684 | 19 | + | 27260157 | HT1080 | viability | CCTGCAGATTGCATGTCCCCTGG | CEACAM6 | ENSG00000086548 | 0.364900619239041 | [] | [] | 3 | hSpCas9 | negative selection | 2653608 | 41755655 | 41755678 | 19 | - | 27260157 | HT1080 | viability | GACATGCAATCTGCAGGGAGGGG | CEACAM6 | ENSG00000086548 | 0.726395549927237 | [] | [] | 6 | hSpCas9 | negative selection | 2681954 | 41756714 | 41756737 | 19 | + | 27260157 | HT1080 | viability | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.889156434690698 | [] | [] | -8 | hSpCas9 | negative selection | 2684088 | 41756704 | 41756727 | 19 | + | 27260157 | HT1080 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.137904698586616 | [] | [] | 1 | hSpCas9 | negative selection | 2689680 | 41755661 | 41755684 | 19 | + | 27260157 | MKN45 | viability | CCTGCAGATTGCATGTCCCCTGG | CEACAM6 | ENSG00000086548 | 0.216616113103414 | [] | [] | 5 | hSpCas9 | negative selection | 2729738 | 41755655 | 41755678 | 19 | - | 27260157 | MKN45 | viability | GACATGCAATCTGCAGGGAGGGG | CEACAM6 | ENSG00000086548 | 0.17335058232233 | [] | [] | 5 | hSpCas9 | negative selection | 2758084 | 41756714 | 41756737 | 19 | + | 27260157 | MKN45 | viability | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.503079941879454 | [] | [] | -6 | hSpCas9 | negative selection | 2760218 | 41756704 | 41756727 | 19 | + | 27260157 | MKN45 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.58435698577054 | [] | [] | -6 | hSpCas9 | negative selection | 2765810 | 41755661 | 41755684 | 19 | + | 27260157 | RKO | viability | CCTGCAGATTGCATGTCCCCTGG | CEACAM6 | ENSG00000086548 | 0.000875520445136738 | [] | [] | 0 | hSpCas9 | negative selection | 2805868 | 41755655 | 41755678 | 19 | - | 27260157 | RKO | viability | GACATGCAATCTGCAGGGAGGGG | CEACAM6 | ENSG00000086548 | -0.188731041850005 | [] | [] | -1 | hSpCas9 | negative selection | 2834214 | 41756714 | 41756737 | 19 | + | 27260157 | RKO | viability | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -1.13411828452958 | [] | [] | -8 | hSpCas9 | negative selection | 2836348 | 41756704 | 41756727 | 19 | + | 27260157 | RKO | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.206525454971948 | [] | [] | 1 | hSpCas9 | negative selection | 2841940 | 41755661 | 41755684 | 19 | + | 27260157 | SF268 | viability | CCTGCAGATTGCATGTCCCCTGG | CEACAM6 | ENSG00000086548 | 0.527913992035135 | [] | [] | 8 | hSpCas9 | negative selection | 2881998 | 41755655 | 41755678 | 19 | - | 27260157 | SF268 | viability | GACATGCAATCTGCAGGGAGGGG | CEACAM6 | ENSG00000086548 | 0.708462512085563 | [] | [] | 8 | hSpCas9 | negative selection | 2910344 | 41756714 | 41756737 | 19 | + | 27260157 | SF268 | viability | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 0.284061319204157 | [] | [] | 4 | hSpCas9 | negative selection | 2912478 | 41756704 | 41756727 | 19 | + | 27260157 | SF268 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.014492074561295 | [] | [] | 0 | hSpCas9 | negative selection | 2918070 | 41756715 | 41756738 | 19 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.26913206685379276 | [3,3] | [2,1] | -4 | hSpCas9 | positive selection | 2978394 | 41755660 | 41755683 | 19 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CAGGGGACATGCAATCTGCAGGG | CEACAM6 | ENSG00000086548 | 0.25494778939704266 | [4,3] | [4,3] | 5 | hSpCas9 | positive selection | 2978395 | 41756738 | 41756761 | 19 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TACAAAGGCGAAAGAGTGGATGG | CEACAM6 | ENSG00000086548 | -0.4496325850346224 | [2,2] | [0,1] | -6 | hSpCas9 | positive selection | 2978396 | 41755677 | 41755700 | 19 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.17737910738956655 | [3,2] | [3,0] | -3 | hSpCas9 | positive selection | 2978397 | 41756715 | 41756738 | 19 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 0.04467559090033317 | [3,3] | [4,1] | 0 | hSpCas9 | positive selection | 3046252 | 41755660 | 41755683 | 19 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CAGGGGACATGCAATCTGCAGGG | CEACAM6 | ENSG00000086548 | 0.16410844013688694 | [4,4] | [3,2] | 3 | hSpCas9 | positive selection | 3046253 | 41756738 | 41756761 | 19 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TACAAAGGCGAAAGAGTGGATGG | CEACAM6 | ENSG00000086548 | 0.2333832827669307 | [2,2] | [2,1] | 4 | hSpCas9 | positive selection | 3046254 | 41755677 | 41755700 | 19 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.5616035765663703 | [3,3] | [0,1] | -7 | hSpCas9 | positive selection | 3046255 | 41756704 | 41756727 | | + | 24336571 | A375 | resistance to PLX after 7 days | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.10337623311333843 | [7,6] | [7,7] | 3 | hSpCas9 | positive selection | 3104817 | 41756712 | 41756735 | | - | 24336571 | A375 | resistance to PLX after 7 days | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.13570304992933102 | [20,18] | [15,19] | -4 | hSpCas9 | positive selection | 3104818 | 41756704 | 41756727 | | + | 24336571 | A375 | resistance to PLX after 14 days | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.04110897794934021 | [4,6] | [1,2] | 0 | hSpCas9 | positive selection | 3162610 | 41756712 | 41756735 | | - | 24336571 | A375 | resistance to PLX after 14 days | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.6707459327949612 | [23,24] | [7,5] | -7 | hSpCas9 | positive selection | 3162611 | 41756704 | 41756727 | | + | 24336571 | A375 | viability after 7 days | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.9176720327446352 | [15] | [7,6] | -8 | hSpCas9 | negative selection | 3220403 | 41756712 | 41756735 | | - | 24336571 | A375 | viability after 7 days | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.18742237362344738 | [18] | [20,18] | 3 | hSpCas9 | negative selection | 3220404 | 41756704 | 41756727 | | + | 24336571 | A375 | viability after 14 days | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -1.1656071831831114 | [15] | [4,6] | -9 | hSpCas9 | negative selection | 3278196 | 41756712 | 41756735 | | - | 24336571 | A375 | viability after 14 days | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.4638839344175558 | [18] | [23,24] | 6 | hSpCas9 | negative selection | 3278197 | 41756712 | 41756735 | 19 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.5877127986828672 | [218,240] | [0,0] | -4 | hSpCas9 | positive selection | 3342564 | 41756704 | 41756727 | 19 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.291677716236612 | [307,316] | [3,0] | 1 | hSpCas9 | positive selection | 3342565 | 41756714 | 41756737 | 19 | + | 26780180 | HT29 | viability (Avana library 4 designs) | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 1.63563020396164 | [] | [] | 6 | hSpCas9 | negative selection | 3414724 | 41755660 | 41755683 | 19 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CAGGGGACATGCAATCTGCAGGG | CEACAM6 | ENSG00000086548 | -0.4892508883005 | [] | [] | -7 | hSpCas9 | negative selection | 3414725 | 41756737 | 41756760 | 19 | + | 26780180 | HT29 | viability (Avana library 4 designs) | TACAAAGGCGAAAGAGTGGATGG | CEACAM6 | ENSG00000086548 | 3.31545171672504 | [] | [] | 8 | hSpCas9 | negative selection | 3414726 | 41755677 | 41755700 | 19 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | 3.19015368456557 | [] | [] | 8 | hSpCas9 | negative selection | 3414727 | 41755660 | 41755683 | 19 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CAGGGGACATGCAATCTGCAGGG | CEACAM6 | ENSG00000086548 | 5.23951437539696 | [] | [] | 8 | hSpCas9 | negative selection | 3491382 | 41756714 | 41756737 | 19 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 0.243963605694653 | [] | [] | 0 | hSpCas9 | negative selection | 3491383 | 41755677 | 41755700 | 19 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -9.05063563601648 | [] | [] | -7 | hSpCas9 | negative selection | 3491384 | 41756737 | 41756760 | 19 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TACAAAGGCGAAAGAGTGGATGG | CEACAM6 | ENSG00000086548 | -4.04238529106486 | [] | [] | -4 | hSpCas9 | negative selection | 3491385 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.932200170652516 | [] | [] | 1 | hSpCas9 | negative selection | 3491386 | 41755668 | 41755691 | 19 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATTGCATGTCCCCTGGAAGGAGG | CEACAM6 | ENSG00000086548 | 2.44333695073541 | [] | [] | 3 | hSpCas9 | negative selection | 3491387 | 41755660 | 41755683 | 19 | - | 26780180 | A375 | viability (Avana lentiGuide) | CAGGGGACATGCAATCTGCAGGG | CEACAM6 | ENSG00000086548 | -8.4629291516272 | [] | [] | -9 | hSpCas9 | negative selection | 3600041 | 41756714 | 41756737 | 19 | + | 26780180 | A375 | viability (Avana lentiGuide) | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.140705341557791 | [] | [] | 0 | hSpCas9 | negative selection | 3600042 | 41755677 | 41755700 | 19 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | 12.7498647931818 | [] | [] | 7 | hSpCas9 | negative selection | 3600043 | 41756737 | 41756760 | 19 | + | 26780180 | A375 | viability (Avana lentiGuide) | TACAAAGGCGAAAGAGTGGATGG | CEACAM6 | ENSG00000086548 | 20.3647747282924 | [] | [] | 8 | hSpCas9 | negative selection | 3600044 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | viability (Avana lentiGuide) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -6.38643747371095 | [] | [] | -9 | hSpCas9 | negative selection | 3600045 | 41755668 | 41755691 | 19 | + | 26780180 | A375 | viability (Avana lentiGuide) | ATTGCATGTCCCCTGGAAGGAGG | CEACAM6 | ENSG00000086548 | 4.9990059816708 | [] | [] | 4 | hSpCas9 | negative selection | 3600046 | 41755660 | 41755683 | 19 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CAGGGGACATGCAATCTGCAGGG | CEACAM6 | ENSG00000086548 | 0.19855021753813834 | [5] | [6,6] | 5 | hSpCas9 | positive selection | 3708700 | 41756714 | 41756737 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.058489067271364714 | [5] | [5,4] | -1 | hSpCas9 | positive selection | 3708701 | 41755677 | 41755700 | 19 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.04587475107680897 | [4] | [3,4] | -1 | hSpCas9 | positive selection | 3708702 | 41756737 | 41756760 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TACAAAGGCGAAAGAGTGGATGG | CEACAM6 | ENSG00000086548 | -0.3275814878073285 | [5] | [4,3] | -5 | hSpCas9 | positive selection | 3708703 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.1049587294085291 | [5] | [5,5] | 2 | hSpCas9 | positive selection | 3708704 | 41755668 | 41755691 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATTGCATGTCCCCTGGAAGGAGG | CEACAM6 | ENSG00000086548 | 0.07634157114017948 | [6] | [6,5] | 2 | hSpCas9 | positive selection | 3708705 | 41755660 | 41755683 | 19 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CAGGGGACATGCAATCTGCAGGG | CEACAM6 | ENSG00000086548 | 0.28054262567128563 | [5] | [5,5] | 7 | hSpCas9 | positive selection | 3817307 | 41756714 | 41756737 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.29152246718581515 | [6] | [4,3] | -4 | hSpCas9 | positive selection | 3817308 | 41755677 | 41755700 | 19 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.7700043516446209 | [5] | [2,1] | -7 | hSpCas9 | positive selection | 3817309 | 41756737 | 41756760 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TACAAAGGCGAAAGAGTGGATGG | CEACAM6 | ENSG00000086548 | -0.2890228528058409 | [4] | [2,3] | -4 | hSpCas9 | positive selection | 3817310 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.4023342275387008 | [5] | [5,6] | 9 | hSpCas9 | positive selection | 3817311 | 41755668 | 41755691 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATTGCATGTCCCCTGGAAGGAGG | CEACAM6 | ENSG00000086548 | -0.15550859637932546 | [6] | [5,4] | -2 | hSpCas9 | positive selection | 3817312 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.00283478049953213 | [] | [] | 0 | hSpCas9 | negative selection | 3925467 | 41756712 | 41756735 | 19 | - | 26780180 | A375 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.783996648702156 | [] | [] | 3 | hSpCas9 | negative selection | 3925468 | 41756704 | 41756727 | 19 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.222454655987489 | [] | [] | -6 | hSpCas9 | negative selection | 4033433 | 41756712 | 41756735 | 19 | - | 26780180 | HT29 | viability (GeCKOv2 library) | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.996268240597013 | [] | [] | 4 | hSpCas9 | negative selection | 4033434 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.19861772387935941 | [3] | [1,1] | -5 | hSpCas9 | positive selection | 4126861 | 41756712 | 41756735 | 19 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.033401907025864624 | [4] | [2,2] | -1 | hSpCas9 | positive selection | 4126862 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.29573833234153796 | [4] | [2,3,0,0] | -4 | hSpCas9 | positive selection | 4190883 | 41756712 | 41756735 | 19 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.19407874285192925 | [4] | [1,2,4,0] | 1 | hSpCas9 | positive selection | 4190884 | 41756712 | 41756735 | 19 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.03679499818093812 | [4] | [3,2] | 0 | hSpCas9 | positive selection | 4262644 | 41756704 | 41756727 | 19 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.21691902100867233 | [4] | [4,3] | 4 | hSpCas9 | positive selection | 4262645 | 41756654 | 41756676 | 19 | - | 27760321 | OCIAML3 | viability | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | 0.09006830313619746 | [595,574] | [453,532] | 1 | hSpCas9 | negative selection | 4388331 | 41756715 | 41756737 | 19 | + | 27760321 | OCIAML3 | viability | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.15214348170883119 | [312,312] | [230,207] | -2 | hSpCas9 | negative selection | 4388332 | 41756939 | 41756961 | 19 | - | 27760321 | OCIAML3 | viability | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -1.0057751378825914 | [286,289] | [84,148] | -7 | hSpCas9 | negative selection | 4388333 | 41756654 | 41756676 | 19 | - | 27760321 | OCIAML2 | viability | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -0.37058090824253087 | [595,574] | [322,424] | -4 | hSpCas9 | negative selection | 4471794 | 41756715 | 41756737 | 19 | + | 27760321 | OCIAML2 | viability | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.0073684467592391445 | [312,312] | [206,312] | 0 | hSpCas9 | negative selection | 4471795 | 41756939 | 41756961 | 19 | - | 27760321 | OCIAML2 | viability | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -0.7017005584012818 | [286,289] | [118,176] | -6 | hSpCas9 | negative selection | 4471796 | 41756654 | 41756676 | 19 | - | 27760321 | MV411 | viability | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | 0.49864109515011584 | [595,574] | [651,388] | 3 | hSpCas9 | negative selection | 4555257 | 41756715 | 41756737 | 19 | + | 27760321 | MV411 | viability | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 0.8470118474848847 | [312,312] | [558,92] | 6 | hSpCas9 | negative selection | 4555258 | 41756939 | 41756961 | 19 | - | 27760321 | MV411 | viability | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -2.093061017860814 | [286,289] | [29,66] | -8 | hSpCas9 | negative selection | 4555259 | 41756654 | 41756676 | 19 | - | 27760321 | HL60 | viability | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | 0.006505367656127137 | [595,574] | [557,399] | 0 | hSpCas9 | negative selection | 4638720 | 41756715 | 41756737 | 19 | + | 27760321 | HL60 | viability | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 0.2857277179690879 | [312,312] | [302,322] | 3 | hSpCas9 | negative selection | 4638721 | 41756939 | 41756961 | 19 | - | 27760321 | HL60 | viability | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -0.47813502601255065 | [286,289] | [113,228] | -5 | hSpCas9 | negative selection | 4638722 | 41756654 | 41756676 | 19 | - | 27760321 | HT1080 | viability | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | 0.7829259636461957 | [574,448] | [465,224] | 4 | hSpCas9 | negative selection | 4722183 | 41756715 | 41756737 | 19 | + | 27760321 | HT1080 | viability | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | 0.5746280717188216 | [312,243] | [211,113] | 3 | hSpCas9 | negative selection | 4722184 | 41756939 | 41756961 | 19 | - | 27760321 | HT1080 | viability | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | 3.6483293077299557 | [289,226] | [1353,1222] | 9 | hSpCas9 | negative selection | 4722185 | 41756654 | 41756676 | 19 | - | 27760321 | HT29 | viability after 7 days | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -0.49463537173855204 | [574,448] | [543,306,557] | -6 | hSpCas9 | negative selection | 4805646 | 41756715 | 41756737 | 19 | + | 27760321 | HT29 | viability after 7 days | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.853660112178303 | [312,243] | [191,258,143] | -8 | hSpCas9 | negative selection | 4805647 | 41756939 | 41756961 | 19 | - | 27760321 | HT29 | viability after 7 days | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -1.2823068389357144 | [289,226] | [166,137,109] | -9 | hSpCas9 | negative selection | 4805648 | 41756654 | 41756676 | 19 | - | 27760321 | HT29 | viability after 25 days | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -1.061838413752497 | [574,448] | [218,321,305] | -6 | hSpCas9 | negative selection | 4889109 | 41756715 | 41756737 | 19 | + | 27760321 | HT29 | viability after 25 days | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.9804978954494048 | [312,243] | [115,221,146] | -6 | hSpCas9 | negative selection | 4889110 | 41756939 | 41756961 | 19 | - | 27760321 | HT29 | viability after 25 days | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -1.2912484973225231 | [289,226] | [103,112,148] | -7 | hSpCas9 | negative selection | 4889111 | 41756654 | 41756676 | 19 | - | 27760321 | HT29 | viability after 22 days | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -0.8837886105731126 | [574,448] | [360,305,293] | -6 | hSpCas9 | negative selection | 4972572 | 41756715 | 41756737 | 19 | + | 27760321 | HT29 | viability after 22 days | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.6641119711015457 | [312,243] | [214,208,184] | -5 | hSpCas9 | negative selection | 4972573 | 41756939 | 41756961 | 19 | - | 27760321 | HT29 | viability after 22 days | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -0.1485806170739845 | [289,226] | [238,169,401] | -1 | hSpCas9 | negative selection | 4972574 | 41756654 | 41756676 | 19 | - | 27760321 | HT29 | viability after 19 days | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -1.4230732731521152 | [574,448] | [348,217,105] | -7 | hSpCas9 | negative selection | 5056035 | 41756715 | 41756737 | 19 | + | 27760321 | HT29 | viability after 19 days | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.867400115334584 | [312,243] | [319,155,66] | -6 | hSpCas9 | negative selection | 5056036 | 41756939 | 41756961 | 19 | - | 27760321 | HT29 | viability after 19 days | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -0.9032957131045977 | [289,226] | [66,114,277] | -6 | hSpCas9 | negative selection | 5056037 | 41756654 | 41756676 | 19 | - | 27760321 | HT29 | viability after 16 days | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -1.311249839718865 | [574,448] | [394,153,160] | -7 | hSpCas9 | negative selection | 5139498 | 41756715 | 41756737 | 19 | + | 27760321 | HT29 | viability after 16 days | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -1.0429318873251952 | [312,243] | [178,83,194] | -7 | hSpCas9 | negative selection | 5139499 | 41756939 | 41756961 | 19 | - | 27760321 | HT29 | viability after 16 days | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -0.23902992302134685 | [289,226] | [380,171,196] | -3 | hSpCas9 | negative selection | 5139500 | 41756654 | 41756676 | 19 | - | 27760321 | HT29 | viability after 13 days | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -0.5064088034749946 | [574,448] | [531,318,403] | -5 | hSpCas9 | negative selection | 5222961 | 41756715 | 41756737 | 19 | + | 27760321 | HT29 | viability after 13 days | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -1.1855545485882488 | [312,243] | [148,201,78] | -8 | hSpCas9 | negative selection | 5222962 | 41756939 | 41756961 | 19 | - | 27760321 | HT29 | viability after 13 days | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -0.9569557909612875 | [289,226] | [91,222,148] | -7 | hSpCas9 | negative selection | 5222963 | 41756654 | 41756676 | 19 | - | 27760321 | HT29 | viability after 10 days | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | -0.7384605275767828 | [574,448] | [403,444,303] | -7 | hSpCas9 | negative selection | 5306424 | 41756715 | 41756737 | 19 | + | 27760321 | HT29 | viability after 10 days | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -0.6452255643852727 | [312,243] | [157,292,217] | -6 | hSpCas9 | negative selection | 5306425 | 41756939 | 41756961 | 19 | - | 27760321 | HT29 | viability after 10 days | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | -0.8035585316749473 | [289,226] | [201,180,171] | -7 | hSpCas9 | negative selection | 5306426 | 41756654 | 41756676 | 19 | - | 27760321 | MOLM13 | viability | TCTGCGACATTGAACGGCGTGG | CEACAM6 | ENSG00000086548 | 0.10832329796219503 | [595,574] | [292,410] | 0 | hSpCas9 | negative selection | 5389887 | 41756715 | 41756737 | 19 | + | 27760321 | MOLM13 | viability | GAATCGTATTGGTTACAGCTGG | CEACAM6 | ENSG00000086548 | -1.8605248931648575 | [312,312] | [17,74] | -7 | hSpCas9 | negative selection | 5389888 | 41756939 | 41756961 | 19 | - | 27760321 | MOLM13 | viability | CGGTATACATGGAACTGTCCGG | CEACAM6 | ENSG00000086548 | 0.1519176393062619 | [286,289] | [261,112] | 1 | hSpCas9 | negative selection | 5389889 | 41755592 | 41755615 | 19 | + | 27661255 | K562 | viability | GCTCAAGCTCCTCTACAAAGAGG | CEACAM6 | ENSG00000086548 | 0.010552489558823597 | [235,182] | [211,132] | 0 | dCas9-KRAB | negative selection | 5470113 | 41756712 | 41756735 | 19 | - | 27260156 | BXPC3 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.036280822279599834 | [1078] | [1092,1088,1127,1342] | 0 | hSpCas9 | negative selection | 5535104 | 41756704 | 41756727 | 19 | + | 27260156 | BXPC3 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.28849067649616233 | [1163] | [1382,1443,1479,1663] | 6 | hSpCas9 | negative selection | 5535105 | 41756712 | 41756735 | 19 | - | 27260156 | A673 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.19005828817075288 | [1078] | [1323,1003,1129,1105] | -5 | hSpCas9 | negative selection | 5656355 | 41756704 | 41756727 | 19 | + | 27260156 | A673 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.04513754214649124 | [1163] | [1748,1265,1352,1437] | 1 | hSpCas9 | negative selection | 5656356 | 41756712 | 41756735 | 19 | - | 27260156 | A375 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.07674428681687928 | [1078] | [1315,1306,1622,1090] | 1 | hSpCas9 | negative selection | 5777606 | 41756704 | 41756727 | 19 | + | 27260156 | A375 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.4118219135039358 | [1163] | [2039,1973,1869,1415] | 6 | hSpCas9 | negative selection | 5777607 | 41756712 | 41756735 | 19 | - | 27260156 | COLO741 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.19780515775099405 | [1078] | [1177,1341,1089] | -4 | hSpCas9 | negative selection | 5898857 | 41756704 | 41756727 | 19 | + | 27260156 | COLO741 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.21416287670377354 | [1163] | [1733,1662,1771] | 4 | hSpCas9 | negative selection | 5898858 | 41756712 | 41756735 | 19 | - | 27260156 | CAL120 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.05831259775498676 | [1078] | [1381,1327,1173] | -1 | hSpCas9 | negative selection | 6020108 | 41756704 | 41756727 | 19 | + | 27260156 | CAL120 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.4420710264281176 | [1163] | [1974,1752,2171] | 6 | hSpCas9 | negative selection | 6020109 | 41756712 | 41756735 | 19 | - | 27260156 | CADOES1 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.026142636296766497 | [1078] | [1087,1110,957,926] | 0 | hSpCas9 | negative selection | 6141359 | 41756704 | 41756727 | 19 | + | 27260156 | CADOES1 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.07859914360791365 | [1163] | [1083,1167,1228,1089] | 1 | hSpCas9 | negative selection | 6141360 | 41756712 | 41756735 | 19 | - | 27260156 | EWS502 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.006621465996020426 | [1078] | [1127,1071,1067,1291] | 0 | hSpCas9 | negative selection | 6262610 | 41756704 | 41756727 | 19 | + | 27260156 | EWS502 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.08686321395146113 | [1163] | [1383,1323,1225,1285] | 1 | hSpCas9 | negative selection | 6262611 | 41756712 | 41756735 | 19 | - | 27260156 | EW8 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.16447437153665723 | [1078] | [816,1022,615,695] | -3 | hSpCas9 | negative selection | 6383861 | 41756704 | 41756727 | 19 | + | 27260156 | EW8 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.18040716118740985 | [1163] | [1158,1183,1019,928] | 3 | hSpCas9 | negative selection | 6383862 | 41756712 | 41756735 | 19 | - | 27260156 | CORL105 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.056248499959236975 | [1078] | [1217,1183,1360,1119] | -1 | hSpCas9 | negative selection | 6505112 | 41756704 | 41756727 | 19 | + | 27260156 | CORL105 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.09593192230342518 | [1163] | [1634,1240,1692,1303] | 1 | hSpCas9 | negative selection | 6505113 | 41756712 | 41756735 | 19 | - | 27260156 | HS294T | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.010639653561463902 | [1078] | [466,344,397,447] | 0 | hSpCas9 | negative selection | 6626363 | 41756704 | 41756727 | 19 | + | 27260156 | HS294T | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.8481232833742673 | [1163] | [730,926,791,787] | 9 | hSpCas9 | negative selection | 6626364 | 41756712 | 41756735 | 19 | - | 27260156 | HCC44 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.31722595449655766 | [1078] | [1222,1563,1880,1432] | 5 | hSpCas9 | negative selection | 6747614 | 41756704 | 41756727 | 19 | + | 27260156 | HCC44 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.28383787794245396 | [1163] | [1549,1144,2078,1760] | 4 | hSpCas9 | negative selection | 6747615 | 41756712 | 41756735 | 19 | - | 27260156 | G402 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.11039649843917188 | [1078] | [1727,1008,1298,913] | -1 | hSpCas9 | negative selection | 6868865 | 41756704 | 41756727 | 19 | + | 27260156 | G402 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.29925280582080727 | [1163] | [1457,2095,1926,1493] | 4 | hSpCas9 | negative selection | 6868866 | 41756712 | 41756735 | 19 | - | 27260156 | L33 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.0588051228044546 | [1078] | [1258,387,644,906] | -1 | hSpCas9 | negative selection | 6990116 | 41756704 | 41756727 | 19 | + | 27260156 | L33 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.10086509593821402 | [1163] | [1249,471,809,1301] | 2 | hSpCas9 | negative selection | 6990117 | 41756712 | 41756735 | 19 | - | 27260156 | K562 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.23753630221633903 | [1078] | [658,1646,1464,770] | 3 | hSpCas9 | negative selection | 7111367 | 41756704 | 41756727 | 19 | + | 27260156 | K562 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.49692444938026425 | [1163] | [1916,2169,942,931] | 6 | hSpCas9 | negative selection | 7111368 | 41756712 | 41756735 | 19 | - | 27260156 | HT29 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.08761153084934303 | [1078] | [1322,1782,1273,1232] | 1 | hSpCas9 | negative selection | 7232618 | 41756704 | 41756727 | 19 | + | 27260156 | HT29 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.2671962960608747 | [1163] | [2193,1866,1500,1334] | 5 | hSpCas9 | negative selection | 7232619 | 41756712 | 41756735 | 19 | - | 27260156 | MHHES1 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.05407969421676562 | [1078] | [1518,1165,1211,870] | -1 | hSpCas9 | negative selection | 7353869 | 41756704 | 41756727 | 19 | + | 27260156 | MHHES1 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.3606675778870414 | [1163] | [1780,1885,1898,1261] | 6 | hSpCas9 | negative selection | 7353870 | 41756712 | 41756735 | 19 | - | 27260156 | MEWO | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.13141458113261772 | [1078] | [975,733,1065] | -3 | hSpCas9 | negative selection | 7475120 | 41756704 | 41756727 | 19 | + | 27260156 | MEWO | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.23114370419910868 | [1163] | [1380,1338,1133] | 5 | hSpCas9 | negative selection | 7475121 | 41756712 | 41756735 | 19 | - | 27260156 | LNCAPCLONEFGC | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.3102988310540282 | [1078] | [1259,1190,1046,1324] | 5 | hSpCas9 | negative selection | 7596371 | 41756704 | 41756727 | 19 | + | 27260156 | LNCAPCLONEFGC | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.3198618959383792 | [1163] | [1359,1132,1545,1269] | 5 | hSpCas9 | negative selection | 7596372 | 41756712 | 41756735 | 19 | - | 27260156 | PANC0327 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.1636742019854327 | [1078] | [1064,1145,985,1086] | 2 | hSpCas9 | negative selection | 7717622 | 41756704 | 41756727 | 19 | + | 27260156 | PANC0327 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.47870472935101605 | [1163] | [1924,1253,1029,1616] | 7 | hSpCas9 | negative selection | 7717623 | 41756712 | 41756735 | 19 | - | 27260156 | NCIH2009 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.0026558011490820377 | [1078] | [1626,1533,1389] | 0 | hSpCas9 | negative selection | 7838873 | 41756704 | 41756727 | 19 | + | 27260156 | NCIH2009 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.41545454122970704 | [1163] | [2939,1934,1784] | 6 | hSpCas9 | negative selection | 7838874 | 41756712 | 41756735 | 19 | - | 27260156 | NCIH1373 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.684311059431824 | [1078] | [2828,1801,1577,446] | 6 | hSpCas9 | negative selection | 7960124 | 41756704 | 41756727 | 19 | + | 27260156 | NCIH1373 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.8421888926590464 | [1163] | [2517,2238,2831,458] | 8 | hSpCas9 | negative selection | 7960125 | 41756712 | 41756735 | 19 | - | 27260156 | PATU8902 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.4329014807466758 | [1078] | [1867,1732,2021,2538] | 4 | hSpCas9 | negative selection | 8081375 | 41756704 | 41756727 | 19 | + | 27260156 | PATU8902 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.40474183076878645 | [1163] | [2129,2090,1956,2477] | 4 | hSpCas9 | negative selection | 8081376 | 41756712 | 41756735 | 19 | - | 27260156 | PANC1 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.1998525564075475 | [1078] | [1129,821,1116,1111] | 3 | hSpCas9 | negative selection | 8202626 | 41756704 | 41756727 | 19 | + | 27260156 | PANC1 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.45032624679244093 | [1163] | [1377,1499,1261,1332] | 7 | hSpCas9 | negative selection | 8202627 | 41756712 | 41756735 | 19 | - | 27260156 | PANC0813 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.17517630200360879 | [1078] | [1761,1221,1505,1271] | 3 | hSpCas9 | negative selection | 8323877 | 41756704 | 41756727 | 19 | + | 27260156 | PANC0813 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.3605027007034436 | [1163] | [1595,1802,1773,1826] | 6 | hSpCas9 | negative selection | 8323878 | 41756712 | 41756735 | 19 | - | 27260156 | RDES | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.1521378172511305 | [1078] | [1289,1240,1476,1519] | 2 | hSpCas9 | negative selection | 8445128 | 41756704 | 41756727 | 19 | + | 27260156 | RDES | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.15551209414152423 | [1163] | [1207,1476,1779,1532] | 2 | hSpCas9 | negative selection | 8445129 | 41756712 | 41756735 | 19 | - | 27260156 | PC3 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.11493989652414993 | [1078] | [692,1050,1539,918] | -3 | hSpCas9 | negative selection | 8566379 | 41756704 | 41756727 | 19 | + | 27260156 | PC3 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.03119627977193251 | [1163] | [750,1119,2166,1163] | 0 | hSpCas9 | negative selection | 8566380 | 41756712 | 41756735 | 19 | - | 27260156 | PATU8988T | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.0960911745961528 | [1078] | [1129,1153,1043,1135] | 1 | hSpCas9 | negative selection | 8687630 | 41756704 | 41756727 | 19 | + | 27260156 | PATU8988T | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.3876948391200552 | [1163] | [1685,1420,1172,1616] | 6 | hSpCas9 | negative selection | 8687631 | 41756712 | 41756735 | 19 | - | 27260156 | T47D | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.08269761153243937 | [1078] | [1242,1139,1160,1208] | -2 | hSpCas9 | negative selection | 8808881 | 41756704 | 41756727 | 19 | + | 27260156 | T47D | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.29353443806811796 | [1163] | [1658,1579,1573,1848] | 6 | hSpCas9 | negative selection | 8808882 | 41756712 | 41756735 | 19 | - | 27260156 | SU8686 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | 0.1331198351003764 | [1078] | [1107,1007,1175,1468] | 2 | hSpCas9 | negative selection | 8930132 | 41756704 | 41756727 | 19 | + | 27260156 | SU8686 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.5371462475415709 | [1163] | [1600,1257,1932,2019] | 8 | hSpCas9 | negative selection | 8930133 | 41756712 | 41756735 | 19 | - | 27260156 | SKES1 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.14191855618860116 | [1078] | [1027,947,975,946] | -3 | hSpCas9 | negative selection | 9051383 | 41756704 | 41756727 | 19 | + | 27260156 | SKES1 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.22717119183232537 | [1163] | [1740,1409,1211,1145] | 5 | hSpCas9 | negative selection | 9051384 | 41756712 | 41756735 | 19 | - | 27260156 | TOV112D | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.15728825333468444 | [1078] | [1005,1168,894,859] | -3 | hSpCas9 | negative selection | 9172634 | 41756704 | 41756727 | 19 | + | 27260156 | TOV112D | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.2517290903300715 | [1163] | [1464,2101,955,1213] | 5 | hSpCas9 | negative selection | 9172635 | 41756712 | 41756735 | 19 | - | 27260156 | TC71 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.1414891233437725 | [1078] | [1161,998,991,1039] | -4 | hSpCas9 | negative selection | 9293885 | 41756704 | 41756727 | 19 | + | 27260156 | TC71 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | 0.18160553483163455 | [1163] | [1660,1471,1122,1407] | 4 | hSpCas9 | negative selection | 9293886 | 41756712 | 41756735 | 19 | - | 27260156 | TC32 | viability | AGCTGTAACCAATACGATTCTGG | CEACAM6 | ENSG00000086548 | -0.06530394189958577 | [1078] | [1059,706,1222,957] | -1 | hSpCas9 | negative selection | 9415136 | 41756704 | 41756727 | 19 | + | 27260156 | TC32 | viability | AACCTGCCCCAGAATCGTATTGG | CEACAM6 | ENSG00000086548 | -0.10175673855569456 | [1163] | [965,768,1185,1237] | -2 | hSpCas9 | negative selection | 9415137 | 41755657 | 41755680 | 19 | - | 28162770 | P31FUJ | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | 0.708304106532053 | [49] | [95] | 7 | hSpCas9 | negative selection | 10131259 | 41755677 | 41755700 | 19 | - | 28162770 | P31FUJ | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.23899847037828414 | [699] | [696] | -2 | hSpCas9 | negative selection | 10131260 | 41756622 | 41756645 | 19 | - | 28162770 | P31FUJ | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.08845314854384823 | [428] | [535] | 0 | hSpCas9 | negative selection | 10131261 | 41756700 | 41756723 | 19 | - | 28162770 | P31FUJ | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | -0.06679225297544944 | [81] | [91] | 0 | hSpCas9 | negative selection | 10131262 | 41756733 | 41756756 | 19 | + | 28162770 | P31FUJ | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.07454490687638327 | [357] | [442] | 0 | hSpCas9 | negative selection | 10131263 | 41755657 | 41755680 | 19 | - | 28162770 | TF1 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | NaN | [NaN] | [64] | 1 | hSpCas9 | negative selection | 10300625 | 41755677 | 41755700 | 19 | - | 28162770 | TF1 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | NaN | [NaN] | [355] | 1 | hSpCas9 | negative selection | 10300626 | 41756622 | 41756645 | 19 | - | 28162770 | TF1 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | NaN | [NaN] | [195] | 1 | hSpCas9 | negative selection | 10300627 | 41756700 | 41756723 | 19 | - | 28162770 | TF1 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | NaN | [NaN] | [117] | 1 | hSpCas9 | negative selection | 10300628 | 41756733 | 41756756 | 19 | + | 28162770 | TF1 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | NaN | [NaN] | [364] | 1 | hSpCas9 | negative selection | 10300629 | 41755657 | 41755680 | 19 | - | 28162770 | SKM1 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.3074285251922473 | [27] | [39] | -3 | hSpCas9 | negative selection | 10469991 | 41755677 | 41755700 | 19 | - | 28162770 | SKM1 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.5901860227989317 | [217] | [255] | -5 | hSpCas9 | negative selection | 10469992 | 41756622 | 41756645 | 19 | - | 28162770 | SKM1 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.5020942335480671 | [132] | [332] | 5 | hSpCas9 | negative selection | 10469993 | 41756700 | 41756723 | 19 | - | 28162770 | SKM1 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.05935380547937541 | [18] | [34] | 0 | hSpCas9 | negative selection | 10469994 | 41756733 | 41756756 | 19 | + | 28162770 | SKM1 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.3829297532482201 | [94] | [218] | 4 | hSpCas9 | negative selection | 10469995 | 41755657 | 41755680 | 19 | - | 28162770 | SKM1 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.3074285251922473 | [27] | [39] | -3 | hSpCas9 | negative selection | 10639357 | 41755677 | 41755700 | 19 | - | 28162770 | SKM1 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.5901860227989317 | [217] | [255] | -5 | hSpCas9 | negative selection | 10639358 | 41756622 | 41756645 | 19 | - | 28162770 | SKM1 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.5020942335480671 | [132] | [332] | 5 | hSpCas9 | negative selection | 10639359 | 41756700 | 41756723 | 19 | - | 28162770 | SKM1 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.05935380547937541 | [18] | [34] | 0 | hSpCas9 | negative selection | 10639360 | 41756733 | 41756756 | 19 | + | 28162770 | SKM1 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.3829297532482201 | [94] | [218] | 4 | hSpCas9 | negative selection | 10639361 | 41755657 | 41755680 | 19 | - | 28162770 | PL21 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | 1.2001396144893202 | [75] | [75] | 8 | hSpCas9 | negative selection | 10808723 | 41755677 | 41755700 | 19 | - | 28162770 | PL21 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.39551748702807266 | [676] | [223] | -3 | hSpCas9 | negative selection | 10808724 | 41756622 | 41756645 | 19 | - | 28162770 | PL21 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | -0.15648119856420184 | [483] | [188] | -1 | hSpCas9 | negative selection | 10808725 | 41756700 | 41756723 | 19 | - | 28162770 | PL21 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | -3.1217884803980427 | [39] | [1] | -9 | hSpCas9 | negative selection | 10808726 | 41756733 | 41756756 | 19 | + | 28162770 | PL21 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.684718047021241 | [242] | [169] | 6 | hSpCas9 | negative selection | 10808727 | 41755657 | 41755680 | 19 | - | 28162770 | P31FUJ | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | 0.708304106532053 | [49] | [95] | 7 | hSpCas9 | negative selection | 10978089 | 41755677 | 41755700 | 19 | - | 28162770 | P31FUJ | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.23899847037828414 | [699] | [696] | -2 | hSpCas9 | negative selection | 10978090 | 41756622 | 41756645 | 19 | - | 28162770 | P31FUJ | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.08845314854384823 | [428] | [535] | 0 | hSpCas9 | negative selection | 10978091 | 41756700 | 41756723 | 19 | - | 28162770 | P31FUJ | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | -0.06679225297544944 | [81] | [91] | 0 | hSpCas9 | negative selection | 10978092 | 41756733 | 41756756 | 19 | + | 28162770 | P31FUJ | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.07454490687638327 | [357] | [442] | 0 | hSpCas9 | negative selection | 10978093 | 41755657 | 41755680 | 19 | - | 28162770 | OCIAML5 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.19115521690954218 | [73] | [116] | -1 | hSpCas9 | negative selection | 11147455 | 41755677 | 41755700 | 19 | - | 28162770 | OCIAML5 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.38909459452145145 | [332] | [458] | -3 | hSpCas9 | negative selection | 11147456 | 41756622 | 41756645 | 19 | - | 28162770 | OCIAML5 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.6714953851930158 | [223] | [643] | 6 | hSpCas9 | negative selection | 11147457 | 41756700 | 41756723 | 19 | - | 28162770 | OCIAML5 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.08204549347954593 | [55] | [106] | 0 | hSpCas9 | negative selection | 11147458 | 41756733 | 41756756 | 19 | + | 28162770 | OCIAML5 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.3144726157389335 | [236] | [531] | 2 | hSpCas9 | negative selection | 11147459 | 41755657 | 41755680 | 19 | - | 28162770 | EOL1 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -1.8828071504870696 | [146] | [20] | -8 | hSpCas9 | negative selection | 11316821 | 41755677 | 41755700 | 19 | - | 28162770 | EOL1 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.41765015229511193 | [1325] | [522] | -3 | hSpCas9 | negative selection | 11316822 | 41756622 | 41756645 | 19 | - | 28162770 | EOL1 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | -0.18887828976381948 | [819] | [378] | -1 | hSpCas9 | negative selection | 11316823 | 41756700 | 41756723 | 19 | - | 28162770 | EOL1 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.38239835438835135 | [82] | [56] | 3 | hSpCas9 | negative selection | 11316824 | 41756733 | 41756756 | 19 | + | 28162770 | EOL1 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.4426787638134819 | [323] | [231] | 4 | hSpCas9 | negative selection | 11316825 | 41755657 | 41755680 | 19 | - | 28162770 | MOLM13 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -1.0466837912851794 | [159] | [55] | -5 | hSpCas9 | negative selection | 11486187 | 41755677 | 41755700 | 19 | - | 28162770 | MOLM13 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.10844594182387324 | [916] | [614] | 0 | hSpCas9 | negative selection | 11486188 | 41756622 | 41756645 | 19 | - | 28162770 | MOLM13 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.8985237358744409 | [666] | [898] | 7 | hSpCas9 | negative selection | 11486189 | 41756700 | 41756723 | 19 | - | 28162770 | MOLM13 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.28147625731369774 | [65] | [57] | 2 | hSpCas9 | negative selection | 11486190 | 41756733 | 41756756 | 19 | + | 28162770 | MOLM13 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.2000264436939555 | [418] | [347] | 1 | hSpCas9 | negative selection | 11486191 | 41755657 | 41755680 | 19 | - | 28162770 | HEL | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | 0.7895802203296282 | [111] | [123] | 6 | hSpCas9 | negative selection | 11655553 | 41755677 | 41755700 | 19 | - | 28162770 | HEL | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | 0.18523724046145906 | [746] | [543] | 1 | hSpCas9 | negative selection | 11655554 | 41756622 | 41756645 | 19 | - | 28162770 | HEL | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.8145806725376419 | [584] | [658] | 7 | hSpCas9 | negative selection | 11655555 | 41756700 | 41756723 | 19 | - | 28162770 | HEL | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.8303658351761282 | [71] | [81] | 7 | hSpCas9 | negative selection | 11655556 | 41756733 | 41756756 | 19 | + | 28162770 | HEL | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.6706628335627958 | [306] | [312] | 6 | hSpCas9 | negative selection | 11655557 | 41755657 | 41755680 | 19 | - | 28162770 | MV411 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | 0.15185989080054418 | [77] | [72] | 1 | hSpCas9 | negative selection | 11824919 | 41755677 | 41755700 | 19 | - | 28162770 | MV411 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -1.1420036326292136 | [688] | [262] | -6 | hSpCas9 | negative selection | 11824920 | 41756622 | 41756645 | 19 | - | 28162770 | MV411 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.3488395829909883 | [411] | [441] | 3 | hSpCas9 | negative selection | 11824921 | 41756700 | 41756723 | 19 | - | 28162770 | MV411 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 1.1702696902603154 | [47] | [90] | 9 | hSpCas9 | negative selection | 11824922 | 41756733 | 41756756 | 19 | + | 28162770 | MV411 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | -0.548767246758107 | [289] | [166] | -4 | hSpCas9 | negative selection | 11824923 | 41755657 | 41755680 | 19 | - | 28162770 | MONOMAC1 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.9340024412257599 | [54] | [32] | -6 | hSpCas9 | negative selection | 11994285 | 41755677 | 41755700 | 19 | - | 28162770 | MONOMAC1 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | 0.09949447076232731 | [446] | [548] | 1 | hSpCas9 | negative selection | 11994286 | 41756622 | 41756645 | 19 | - | 28162770 | MONOMAC1 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | -0.09379574115820688 | [336] | [361] | -1 | hSpCas9 | negative selection | 11994287 | 41756700 | 41756723 | 19 | - | 28162770 | MONOMAC1 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.8751129386962816 | [38] | [81] | 7 | hSpCas9 | negative selection | 11994288 | 41756733 | 41756756 | 19 | + | 28162770 | MONOMAC1 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.3801900048819973 | [186] | [278] | 4 | hSpCas9 | negative selection | 11994289 | 41755657 | 41755680 | 19 | - | 28162770 | OCIAML2 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -1.5164335148552859 | [15] | [30] | -7 | hSpCas9 | negative selection | 12163651 | 41755677 | 41755700 | 19 | - | 28162770 | OCIAML2 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | -0.31097315925367575 | [140] | [629] | -3 | hSpCas9 | negative selection | 12163652 | 41756622 | 41756645 | 19 | - | 28162770 | OCIAML2 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.41046476948901955 | [78] | [581] | 4 | hSpCas9 | negative selection | 12163653 | 41756700 | 41756723 | 19 | - | 28162770 | OCIAML2 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.7517625960942865 | [11] | [111] | 7 | hSpCas9 | negative selection | 12163654 | 41756733 | 41756756 | 19 | + | 28162770 | OCIAML2 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 0.6919903755769177 | [43] | [393] | 6 | hSpCas9 | negative selection | 12163655 | 41755657 | 41755680 | 19 | - | 28162770 | OCIAML3 | viability | GGGACATGCAATCTGCAGGGAGG | CEACAM6 | ENSG00000086548 | -0.1880152806483264 | [19] | [52] | -1 | hSpCas9 | negative selection | 12333017 | 41755677 | 41755700 | 19 | - | 28162770 | OCIAML3 | viability | TGAGCAGGACCTCCTTCCAGGGG | CEACAM6 | ENSG00000086548 | 0.2954659022069457 | [199] | [740] | 2 | hSpCas9 | negative selection | 12333018 | 41756622 | 41756645 | 19 | - | 28162770 | OCIAML3 | viability | TGAGCTTGGCAGTGGTGGGTGGG | CEACAM6 | ENSG00000086548 | 0.5413442125707231 | [121] | [535] | 5 | hSpCas9 | negative selection | 12333019 | 41756700 | 41756723 | 19 | - | 28162770 | OCIAML3 | viability | TACGATTCTGGGGCAGGTTGTGG | CEACAM6 | ENSG00000086548 | 0.8914191868460783 | [9] | [55] | 7 | hSpCas9 | negative selection | 12333020 | 41756733 | 41756756 | 19 | + | 28162770 | OCIAML3 | viability | CTGGTACAAAGGCGAAAGAGTGG | CEACAM6 | ENSG00000086548 | 1.0547307708303075 | [58] | [369] | 8 | hSpCas9 | negative selection | 12333021 |