| 37321835 | 37321858 | 18 | - | 26472758 | Jiyoye | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 1.4851778935071462 | [26] | [56] | 8 | hSpCas9 | negative selection | 29689 | 37270884 | 37270907 | 18 | + | 26472758 | Jiyoye | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 1.0564882936370872 | [94] | [148] | 7 | hSpCas9 | negative selection | 29690 | 37264701 | 37264724 | 18 | + | 26472758 | Jiyoye | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -1.3813205133004152 | [75] | [21] | -7 | hSpCas9 | negative selection | 29691 | 37565542 | 37565565 | 18 | + | 26472758 | Jiyoye | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.40044951831756004 | [214] | [213] | 3 | hSpCas9 | negative selection | 29692 | 37565519 | 37565542 | 18 | - | 26472758 | Jiyoye | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.7434587693703059 | [159] | [201] | 5 | hSpCas9 | negative selection | 29693 | 37321835 | 37321858 | 18 | - | 26472758 | KBM7 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.30071635343817804 | [158,134] | [68,98] | 3 | hSpCas9 | negative selection | 220807 | 37270884 | 37270907 | 18 | + | 26472758 | KBM7 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.8129696162457007 | [374,343] | [266,323] | 8 | hSpCas9 | negative selection | 220808 | 37264701 | 37264724 | 18 | + | 26472758 | KBM7 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.4216015395564137 | [417,506] | [65,18] | -9 | hSpCas9 | negative selection | 220809 | 37565542 | 37565565 | 18 | + | 26472758 | KBM7 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.41192363948988664 | [865,809] | [581,473] | 4 | hSpCas9 | negative selection | 220810 | 37565519 | 37565542 | 18 | - | 26472758 | KBM7 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.4588837561799761 | [804,535] | [406,443] | 5 | hSpCas9 | negative selection | 220811 | 37321835 | 37321858 | 18 | - | 26472758 | Raji | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | -0.7185870648513513 | [77] | [10] | -5 | hSpCas9 | negative selection | 411925 | 37270884 | 37270907 | 18 | + | 26472758 | Raji | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | -0.14811719777478688 | [190] | [39] | -1 | hSpCas9 | negative selection | 411926 | 37264701 | 37264724 | 18 | + | 26472758 | Raji | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -1.390867332154226 | [225] | [19] | -7 | hSpCas9 | negative selection | 411927 | 37565542 | 37565565 | 18 | + | 26472758 | Raji | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | -0.08526154256879637 | [575] | [125] | 0 | hSpCas9 | negative selection | 411928 | 37565519 | 37565542 | 18 | - | 26472758 | Raji | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.49346966095631417 | [452] | [147] | 5 | hSpCas9 | negative selection | 411929 | 37321835 | 37321858 | 18 | - | 26472758 | K562 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 1.1032426647057525 | [117] | [213] | 8 | hSpCas9 | negative selection | 603043 | 37270884 | 37270907 | 18 | + | 26472758 | K562 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.7100823000152585 | [188] | [260] | 6 | hSpCas9 | negative selection | 603044 | 37264701 | 37264724 | 18 | + | 26472758 | K562 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -3.5549874412756663 | [361] | [25] | -8 | hSpCas9 | negative selection | 603045 | 37565542 | 37565565 | 18 | + | 26472758 | K562 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | -0.26057546835129414 | [578] | [407] | -2 | hSpCas9 | negative selection | 603046 | 37565519 | 37565542 | 18 | - | 26472758 | K562 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.6340336300653839 | [457] | [599] | 5 | hSpCas9 | negative selection | 603047 | 37273121 | 37273144 | 18 | - | 26627737 | DLD1 | viability | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.07228725150784068 | [512] | [107,146,238] | 0 | hSpCas9 | negative selection | 801495 | 37321790 | 37321813 | 18 | + | 26627737 | DLD1 | viability | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 0.5149261786964122 | [206] | [84,159,42] | 5 | hSpCas9 | negative selection | 801496 | 37485579 | 37485602 | 18 | + | 26627737 | DLD1 | viability | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.07069679352617128 | [437] | [104,130,187] | 0 | hSpCas9 | negative selection | 801497 | 37565519 | 37565542 | 18 | - | 26627737 | DLD1 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.1809474075137507 | [696] | [267,195,270] | 1 | hSpCas9 | negative selection | 801498 | 37273121 | 37273144 | 18 | - | 26627737 | GBM cells | viability after 5 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.8423303465193179 | [142] | [121,152] | 9 | hSpCas9 | negative selection | 883810 | 37321790 | 37321813 | 18 | + | 26627737 | GBM cells | viability after 5 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.3702727579297035 | [140] | [57,58] | -5 | hSpCas9 | negative selection | 883811 | 37485579 | 37485602 | 18 | + | 26627737 | GBM cells | viability after 5 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.060664944882297844 | [294] | [116,212] | 0 | hSpCas9 | negative selection | 883812 | 37565519 | 37565542 | 18 | - | 26627737 | GBM cells | viability after 5 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.04496625852431002 | [412] | [271,184] | 0 | hSpCas9 | negative selection | 883813 | 37273121 | 37273144 | 18 | - | 26627737 | GBM cells | viability after 13 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.9857771671287463 | [142] | [151,154] | 9 | hSpCas9 | negative selection | 966125 | 37321790 | 37321813 | 18 | + | 26627737 | GBM cells | viability after 13 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.44310138574705704 | [140] | [47,62] | -5 | hSpCas9 | negative selection | 966126 | 37485579 | 37485602 | 18 | + | 26627737 | GBM cells | viability after 13 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.2257872584099524 | [294] | [195,179] | 3 | hSpCas9 | negative selection | 966127 | 37565519 | 37565542 | 18 | - | 26627737 | GBM cells | viability after 13 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.4581257880518588 | [412] | [193,137] | -5 | hSpCas9 | negative selection | 966128 | 37273121 | 37273144 | 18 | - | 26627737 | GBM cells | viability after 21 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.6811362156094949 | [142] | [122,125] | 7 | hSpCas9 | negative selection | 1048440 | 37321790 | 37321813 | 18 | + | 26627737 | GBM cells | viability after 21 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.5435466808860524 | [140] | [62,42] | -5 | hSpCas9 | negative selection | 1048441 | 37485579 | 37485602 | 18 | + | 26627737 | GBM cells | viability after 21 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.6283710511409764 | [294] | [241,252] | 6 | hSpCas9 | negative selection | 1048442 | 37565519 | 37565542 | 18 | - | 26627737 | GBM cells | viability after 21 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.03642216497441242 | [412] | [250,210] | 0 | hSpCas9 | negative selection | 1048443 | 37273121 | 37273144 | 18 | - | 26627737 | RPE1 | viability after 9 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.007012519340253709 | [692] | [193,248] | 0 | hSpCas9 | negative selection | 1130755 | 37321790 | 37321813 | 18 | + | 26627737 | RPE1 | viability after 9 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.2795924868176619 | [403] | [46,177] | -2 | hSpCas9 | negative selection | 1130756 | 37485579 | 37485602 | 18 | + | 26627737 | RPE1 | viability after 9 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.15794520872232848 | [1037] | [424,281] | 1 | hSpCas9 | negative selection | 1130757 | 37565519 | 37565542 | 18 | - | 26627737 | RPE1 | viability after 9 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -1.0741557177526835 | [2196] | [289,373] | -7 | hSpCas9 | negative selection | 1130758 | 37273121 | 37273144 | 18 | - | 26627737 | RPE1 | viability after 12 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.21237778169076116 | [692] | [273,153] | 1 | hSpCas9 | negative selection | 1213070 | 37321790 | 37321813 | 18 | + | 26627737 | RPE1 | viability after 12 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.11659602842244998 | [403] | [52,149] | -1 | hSpCas9 | negative selection | 1213071 | 37485579 | 37485602 | 18 | + | 26627737 | RPE1 | viability after 12 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.2545367904930563 | [1037] | [440,217] | 1 | hSpCas9 | negative selection | 1213072 | 37565519 | 37565542 | 18 | - | 26627737 | RPE1 | viability after 12 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -1.0460572129020018 | [2196] | [246,326] | -6 | hSpCas9 | negative selection | 1213073 | 37273121 | 37273144 | 18 | - | 26627737 | RPE1 | viability after 15 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.8729228246734081 | [692] | [498,223] | 5 | hSpCas9 | negative selection | 1295385 | 37321790 | 37321813 | 18 | + | 26627737 | RPE1 | viability after 15 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.3920566749526858 | [403] | [53,118] | -2 | hSpCas9 | negative selection | 1295386 | 37485579 | 37485602 | 18 | + | 26627737 | RPE1 | viability after 15 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | -0.7054811116692468 | [1037] | [288,74] | -4 | hSpCas9 | negative selection | 1295387 | 37565519 | 37565542 | 18 | - | 26627737 | RPE1 | viability after 15 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -1.291065511387278 | [2196] | [311,197] | -7 | hSpCas9 | negative selection | 1295388 | 37273121 | 37273144 | 18 | - | 26627737 | RPE1 | viability after 18 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.4205995824291252 | [692] | [419,68] | 2 | hSpCas9 | negative selection | 1377700 | 37321790 | 37321813 | 18 | + | 26627737 | RPE1 | viability after 18 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 0.23161702041628018 | [403] | [40,220] | 1 | hSpCas9 | negative selection | 1377701 | 37485579 | 37485602 | 18 | + | 26627737 | RPE1 | viability after 18 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | -0.23582309988137332 | [1037] | [248,225] | -1 | hSpCas9 | negative selection | 1377702 | 37565519 | 37565542 | 18 | - | 26627737 | RPE1 | viability after 18 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -1.0881423844194633 | [2196] | [187,375] | -6 | hSpCas9 | negative selection | 1377703 | 37273121 | 37273144 | 18 | - | 26627737 | HeLa | viability after 8 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | -0.13835168514799612 | [318] | [148,72,158] | -1 | hSpCas9 | negative selection | 1460015 | 37321790 | 37321813 | 18 | + | 26627737 | HeLa | viability after 8 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.957809796366066 | [331] | [91,104,32] | -7 | hSpCas9 | negative selection | 1460016 | 37485579 | 37485602 | 18 | + | 26627737 | HeLa | viability after 8 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.35017038153814845 | [510] | [476,281,143] | 3 | hSpCas9 | negative selection | 1460017 | 37565519 | 37565542 | 18 | - | 26627737 | HeLa | viability after 8 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.9487356749298057 | [806] | [211,196,145] | -7 | hSpCas9 | negative selection | 1460018 | 37273121 | 37273144 | 18 | - | 26627737 | HeLa | viability after 12 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.9363314315645979 | [318] | [309,209,242] | 7 | hSpCas9 | negative selection | 1542330 | 37321790 | 37321813 | 18 | + | 26627737 | HeLa | viability after 12 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.014946847742734165 | [331] | [257,68,90] | 0 | hSpCas9 | negative selection | 1542331 | 37485579 | 37485602 | 18 | + | 26627737 | HeLa | viability after 12 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.4621434193301804 | [510] | [245,162,475] | 4 | hSpCas9 | negative selection | 1542332 | 37565519 | 37565542 | 18 | - | 26627737 | HeLa | viability after 12 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.25937881274797847 | [806] | [259,328,240] | -2 | hSpCas9 | negative selection | 1542333 | 37273121 | 37273144 | 18 | - | 26627737 | HeLa | viability after 15 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.9990946839144819 | [318] | [222,334,217] | 7 | hSpCas9 | negative selection | 1624645 | 37321790 | 37321813 | 18 | + | 26627737 | HeLa | viability after 15 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -1.4748816516687775 | [331] | [52,41,50] | -8 | hSpCas9 | negative selection | 1624646 | 37485579 | 37485602 | 18 | + | 26627737 | HeLa | viability after 15 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.3743231798664511 | [510] | [169,276,370] | 3 | hSpCas9 | negative selection | 1624647 | 37565519 | 37565542 | 18 | - | 26627737 | HeLa | viability after 15 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.1544360071090397 | [806] | [182,456,242] | -1 | hSpCas9 | negative selection | 1624648 | 37273121 | 37273144 | 18 | - | 26627737 | HeLa | viability after 18 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.9929765526239265 | [318] | [138,287,217] | 7 | hSpCas9 | negative selection | 1706960 | 37321790 | 37321813 | 18 | + | 26627737 | HeLa | viability after 18 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -1.429580588077273 | [331] | [39,32,50] | -8 | hSpCas9 | negative selection | 1706961 | 37485579 | 37485602 | 18 | + | 26627737 | HeLa | viability after 18 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.38267436084461864 | [510] | [110,236,370] | 3 | hSpCas9 | negative selection | 1706962 | 37565519 | 37565542 | 18 | - | 26627737 | HeLa | viability after 18 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.13773151055853117 | [806] | [120,388,242] | -1 | hSpCas9 | negative selection | 1706963 | 37273121 | 37273144 | 18 | - | 26627737 | HCT116 | viability after 6 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.986917450922818 | [640] | [414,80] | 5 | hSpCas9 | negative selection | 1789275 | 37321790 | 37321813 | 18 | + | 26627737 | HCT116 | viability after 6 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -1.129867331907073 | [386] | [21,30] | -6 | hSpCas9 | negative selection | 1789276 | 37485579 | 37485602 | 18 | + | 26627737 | HCT116 | viability after 6 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.6677090140479902 | [612] | [38,215] | 3 | hSpCas9 | negative selection | 1789277 | 37565519 | 37565542 | 18 | - | 26627737 | HCT116 | viability after 6 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.22014754244481405 | [1351] | [195,174] | -1 | hSpCas9 | negative selection | 1789278 | 37273121 | 37273144 | 18 | - | 26627737 | HCT116 | viability after 8 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.5256440490178641 | [190] | [192,170,91] | 5 | hSpCas9 | negative selection | 1871590 | 37321790 | 37321813 | 18 | + | 26627737 | HCT116 | viability after 8 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 1.8970910583302008 | [67] | [122,123,170] | 9 | hSpCas9 | negative selection | 1871591 | 37485579 | 37485602 | 18 | + | 26627737 | HCT116 | viability after 8 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.12923169221181685 | [408] | [333,157,248] | 1 | hSpCas9 | negative selection | 1871592 | 37565519 | 37565542 | 18 | - | 26627737 | HCT116 | viability after 8 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.08703101148050785 | [563] | [414,260,315] | 1 | hSpCas9 | negative selection | 1871593 | 37273121 | 37273144 | 18 | - | 26627737 | HCT116 | viability after 9 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.8799347585229169 | [640] | [462,197] | 6 | hSpCas9 | negative selection | 1953905 | 37321790 | 37321813 | 18 | + | 26627737 | HCT116 | viability after 9 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -1.0957156383679831 | [386] | [106,1] | -6 | hSpCas9 | negative selection | 1953906 | 37485579 | 37485602 | 18 | + | 26627737 | HCT116 | viability after 9 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.5026672075826526 | [612] | [227,234] | 3 | hSpCas9 | negative selection | 1953907 | 37565519 | 37565542 | 18 | - | 26627737 | HCT116 | viability after 9 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.6469565881561172 | [1351] | [272,196] | -4 | hSpCas9 | negative selection | 1953908 | 37273121 | 37273144 | 18 | - | 26627737 | HCT116 | viability after 12 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 1.0607796531480278 | [190] | [171,231,227] | 8 | hSpCas9 | negative selection | 2036220 | 37321790 | 37321813 | 18 | + | 26627737 | HCT116 | viability after 12 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 2.1066547079774103 | [67] | [78,140,247] | 9 | hSpCas9 | negative selection | 2036221 | 37485579 | 37485602 | 18 | + | 26627737 | HCT116 | viability after 12 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | -0.4703409044642823 | [408] | [142,175,147] | -5 | hSpCas9 | negative selection | 2036222 | 37565519 | 37565542 | 18 | - | 26627737 | HCT116 | viability after 12 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.051860772108461184 | [563] | [308,241,368] | 0 | hSpCas9 | negative selection | 2036223 | 37273121 | 37273144 | 18 | - | 26627737 | HCT116 | viability after 15 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 1.214944321328439 | [190] | [177,358,217] | 8 | hSpCas9 | negative selection | 2118535 | 37321790 | 37321813 | 18 | + | 26627737 | HCT116 | viability after 15 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 2.1980475461519546 | [67] | [123,238,167] | 9 | hSpCas9 | negative selection | 2118536 | 37485579 | 37485602 | 18 | + | 26627737 | HCT116 | viability after 15 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.22909100261405435 | [408] | [245,436,140] | 2 | hSpCas9 | negative selection | 2118537 | 37565519 | 37565542 | 18 | - | 26627737 | HCT116 | viability after 15 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.36773573958650696 | [563] | [230,215,302] | -4 | hSpCas9 | negative selection | 2118538 | 37273121 | 37273144 | 18 | - | 26627737 | HCT116 | viability after 18 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.625413367823732 | [190] | [85,159,181] | 5 | hSpCas9 | negative selection | 2200850 | 37321790 | 37321813 | 18 | + | 26627737 | HCT116 | viability after 18 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 2.0854776971722053 | [67] | [50,137,233] | 9 | hSpCas9 | negative selection | 2200851 | 37485579 | 37485602 | 18 | + | 26627737 | HCT116 | viability after 18 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | -0.06053836860936879 | [408] | [218,175,173] | 0 | hSpCas9 | negative selection | 2200852 | 37565519 | 37565542 | 18 | - | 26627737 | HCT116 | viability after 18 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.02587005040355761 | [563] | [277,181,352] | 0 | hSpCas9 | negative selection | 2200853 | 37565520 | 37565543 | 18 | - | 24336569 | HL60 | viability | AACGGATTAAGCCACAGCCCGGG | CELF4 | ENSG00000101489 | -0.36416848660282364 | [575] | [946] | -3 | hSpCas9 | negative selection | 2257073 | 37565531 | 37565554 | 18 | + | 24336569 | HL60 | viability | GCTTAATCCGTTCATGTGCCCGG | CELF4 | ENSG00000101489 | 0.6686902652938499 | [293] | [988] | 6 | hSpCas9 | negative selection | 2257074 | 37565538 | 37565561 | 18 | - | 24336569 | HL60 | viability | GGCAGTGCCGGGCACATGAACGG | CELF4 | ENSG00000101489 | -0.7975829098894982 | [583] | [710] | -6 | hSpCas9 | negative selection | 2257075 | 37565549 | 37565572 | 18 | - | 24336569 | HL60 | viability | GCAGCAGCCCGGGCAGTGCCGGG | CELF4 | ENSG00000101489 | -1.3527661224462908 | [139] | [115] | -8 | hSpCas9 | negative selection | 2257076 | 37565559 | 37565582 | 18 | - | 24336569 | HL60 | viability | AACGGGCTCGGCAGCAGCCCGGG | CELF4 | ENSG00000101489 | -0.1697636263780613 | [538] | [1013] | -1 | hSpCas9 | negative selection | 2257077 | 37565569 | 37565592 | 18 | + | 24336569 | HL60 | viability | TGCCGAGCCCGTTGGTACTGAGG | CELF4 | ENSG00000101489 | 0.6025457693430689 | [196] | [632] | 5 | hSpCas9 | negative selection | 2257078 | 37565576 | 37565599 | 18 | - | 24336569 | HL60 | viability | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | 0.5494738288926465 | [349] | [1083] | 5 | hSpCas9 | negative selection | 2257079 | 37565603 | 37565626 | 18 | + | 24336569 | HL60 | viability | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | -0.24277955785272887 | [448] | [802] | -2 | hSpCas9 | negative selection | 2257080 | 37565610 | 37565633 | 18 | - | 24336569 | HL60 | viability | AAGATGGCCACGTTAGCAAACGG | CELF4 | ENSG00000101489 | 0.8457954406621628 | [782] | [2977] | 7 | hSpCas9 | negative selection | 2257081 | 37565626 | 37565649 | 18 | - | 24336569 | HL60 | viability | TTTCTCTATGTATATAAAGATGG | CELF4 | ENSG00000101489 | 1.8238990252330285 | [188] | [1415] | 9 | hSpCas9 | negative selection | 2257082 | 37565520 | 37565543 | 18 | - | 24336569 | KBM7 | viability | AACGGATTAAGCCACAGCCCGGG | CELF4 | ENSG00000101489 | -0.02958837988069124 | [304] | [814] | 0 | hSpCas9 | negative selection | 2324250 | 37565531 | 37565554 | 18 | + | 24336569 | KBM7 | viability | GCTTAATCCGTTCATGTGCCCGG | CELF4 | ENSG00000101489 | -0.6983162435792919 | [256] | [431] | -5 | hSpCas9 | negative selection | 2324251 | 37565538 | 37565561 | 18 | - | 24336569 | KBM7 | viability | GGCAGTGCCGGGCACATGAACGG | CELF4 | ENSG00000101489 | 0.5779558955582552 | [335] | [1367] | 5 | hSpCas9 | negative selection | 2324252 | 37565549 | 37565572 | 18 | - | 24336569 | KBM7 | viability | GCAGCAGCCCGGGCAGTGCCGGG | CELF4 | ENSG00000101489 | -0.23542595971727276 | [201] | [467] | -2 | hSpCas9 | negative selection | 2324253 | 37565559 | 37565582 | 18 | - | 24336569 | KBM7 | viability | AACGGGCTCGGCAGCAGCCCGGG | CELF4 | ENSG00000101489 | 0.8149278120789323 | [113] | [546] | 7 | hSpCas9 | negative selection | 2324254 | 37565569 | 37565592 | 18 | + | 24336569 | KBM7 | viability | TGCCGAGCCCGTTGGTACTGAGG | CELF4 | ENSG00000101489 | 0.4004177100060675 | [124] | [449] | 4 | hSpCas9 | negative selection | 2324255 | 37565576 | 37565599 | 18 | - | 24336569 | KBM7 | viability | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | 0.5865465873557439 | [281] | [1154] | 5 | hSpCas9 | negative selection | 2324256 | 37565603 | 37565626 | 18 | + | 24336569 | KBM7 | viability | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | 1.7560766622059796 | [154] | [1427] | 9 | hSpCas9 | negative selection | 2324257 | 37565610 | 37565633 | 18 | - | 24336569 | KBM7 | viability | AAGATGGCCACGTTAGCAAACGG | CELF4 | ENSG00000101489 | 0.8306706877998005 | [616] | [2992] | 7 | hSpCas9 | negative selection | 2324258 | 37565626 | 37565649 | 18 | - | 24336569 | KBM7 | viability | TTTCTCTATGTATATAAAGATGG | CELF4 | ENSG00000101489 | 0.6009193211423076 | [233] | [967] | 5 | hSpCas9 | negative selection | 2324259 | 37360128 | 37360151 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGCATGAGCCACCATGCCGGG | CELF4 | ENSG00000101489 | 0.3888402363631881 | [40,30] | [14,4] | 1 | dCas9-VP64 | positive selection | 2384379 | 37461526 | 37461549 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CACCAGGTCCCTCCCACAACGGG | CELF4 | ENSG00000101489 | 1.373288406874937 | [589,582] | [407,255] | 5 | dCas9-VP64 | positive selection | 2387898 | 37296229 | 37296252 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TACTGCAGCCTCTGCCTTCCAGG | CELF4 | ENSG00000101489 | -1.8629537168229047 | [109,575] | [11,29] | -8 | dCas9-VP64 | positive selection | 2411026 | 37335495 | 37335518 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GTGTGTGTGTGTGTGTGTGGAGG | CELF4 | ENSG00000101489 | 1.250295307438589 | [24,5] | [12,2] | 5 | dCas9-VP64 | positive selection | 2434546 | 37335494 | 37335517 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGTGTGTGTGTGTGTGTGTGGAG | CELF4 | ENSG00000101489 | 4.012697497775513 | [34,46] | [124,170] | 9 | dCas9-VP64 | positive selection | 2437037 | 37360128 | 37360151 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGCATGAGCCACCATGCCGGG | CELF4 | ENSG00000101489 | 0.501495088189527 | [102,55] | [55,18] | 4 | dCas9-VP64 | positive selection | 2479634 | 37461526 | 37461549 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CACCAGGTCCCTCCCACAACGGG | CELF4 | ENSG00000101489 | 0.3715532225034628 | [214,308] | [113,106] | 3 | dCas9-VP64 | positive selection | 2483153 | 37296229 | 37296252 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TACTGCAGCCTCTGCCTTCCAGG | CELF4 | ENSG00000101489 | 0.19869405022527492 | [66,100] | [28,32] | 1 | dCas9-VP64 | positive selection | 2506281 | 37335495 | 37335518 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GTGTGTGTGTGTGTGTGTGGAGG | CELF4 | ENSG00000101489 | 0.8668431868856517 | [26,20] | [22,6] | 6 | dCas9-VP64 | positive selection | 2529801 | 37335494 | 37335517 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGTGTGTGTGTGTGTGTGTGGAG | CELF4 | ENSG00000101489 | 0.624785689505321 | [134,23] | [72,8] | 4 | dCas9-VP64 | positive selection | 2532292 | 37565576 | 37565599 | 18 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | 0.14642205275601483 | [3,3] | [3,3] | 3 | hSpCas9 | positive selection | 2978474 | 37565576 | 37565599 | 18 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | -0.31455287829618966 | [3,3] | [2,1] | -5 | hSpCas9 | positive selection | 3046332 | 37565603 | 37565626 | | + | 24336571 | A375 | resistance to PLX after 7 days | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | 0.12442172989030764 | [76,63] | [77,74] | 4 | hSpCas9 | positive selection | 3104890 | 37565494 | 37565517 | | - | 24336571 | A375 | resistance to PLX after 7 days | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | -0.08344076957361146 | [67,64] | [69,54] | -2 | hSpCas9 | positive selection | 3104891 | 37485563 | 37485586 | | - | 24336571 | A375 | resistance to PLX after 7 days | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.2780297725854536 | [26,21] | [17,21] | -7 | hSpCas9 | positive selection | 3104892 | 37485570 | 37485593 | | + | 24336571 | A375 | resistance to PLX after 7 days | CGCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | -0.4418998287611341 | [25,31] | [30,10] | -9 | hSpCas9 | positive selection | 3104893 | 37565603 | 37565626 | | + | 24336571 | A375 | resistance to PLX after 14 days | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | 0.17493941649283595 | [81,77] | [41,41] | 1 | hSpCas9 | positive selection | 3162683 | 37565494 | 37565517 | | - | 24336571 | A375 | resistance to PLX after 14 days | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.19173255378132525 | [70,74] | [33,43] | 2 | hSpCas9 | positive selection | 3162684 | 37485563 | 37485586 | | - | 24336571 | A375 | resistance to PLX after 14 days | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.4149401853730544 | [22,22] | [4,9] | -5 | hSpCas9 | positive selection | 3162685 | 37485570 | 37485593 | | + | 24336571 | A375 | resistance to PLX after 14 days | CGCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.3395658251008673 | [23,28] | [14,15] | 3 | hSpCas9 | positive selection | 3162686 | 37565603 | 37565626 | | + | 24336571 | A375 | viability after 7 days | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | 0.5883963467986382 | [48] | [76,63] | 8 | hSpCas9 | negative selection | 3220476 | 37565494 | 37565517 | | - | 24336571 | A375 | viability after 7 days | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.012450582138278321 | [68] | [67,64] | 0 | hSpCas9 | negative selection | 3220477 | 37485563 | 37485586 | | - | 24336571 | A375 | viability after 7 days | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 2.2718255460464305 | [4] | [26,21] | 9 | hSpCas9 | negative selection | 3220478 | 37485570 | 37485593 | | + | 24336571 | A375 | viability after 7 days | CGCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 2.9936343873908267 | [2] | [25,31] | 9 | hSpCas9 | negative selection | 3220479 | 37565603 | 37565626 | | + | 24336571 | A375 | viability after 14 days | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | 0.7770232046594425 | [48] | [81,77] | 8 | hSpCas9 | negative selection | 3278269 | 37565494 | 37565517 | | - | 24336571 | A375 | viability after 14 days | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.16375998641789513 | [68] | [70,74] | 2 | hSpCas9 | negative selection | 3278270 | 37485563 | 37485586 | | - | 24336571 | A375 | viability after 14 days | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 2.180454534674002 | [4] | [22,22] | 9 | hSpCas9 | negative selection | 3278271 | 37485570 | 37485593 | | + | 24336571 | A375 | viability after 14 days | CGCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 2.8743413809309715 | [2] | [23,28] | 9 | hSpCas9 | negative selection | 3278272 | 37565494 | 37565517 | 18 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 1.4257602263205786 | [48,64] | [0,0] | 6 | hSpCas9 | positive selection | 3342625 | 37485539 | 37485562 | 18 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.06750165256581787 | [145,145] | [0,0] | 0 | hSpCas9 | positive selection | 3361857 | 37485563 | 37485586 | 18 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.8310614567437372 | [85,85] | [0,0] | 4 | hSpCas9 | positive selection | 3361858 | 37565521 | 37565544 | 18 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.9905396707509337 | [76,76] | [0,0] | 4 | hSpCas9 | positive selection | 3361859 | 37565576 | 37565599 | 18 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | 0.876484664707698 | [] | [] | 3 | hSpCas9 | negative selection | 3414806 | 37565576 | 37565599 | 18 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | -0.402724287360181 | [] | [] | 0 | hSpCas9 | negative selection | 3491503 | 37485524 | 37485547 | 18 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CGAGCAGAAGACTCTGCCCGGGG | CELF4 | ENSG00000101489 | 3.4984933721252 | [] | [] | 5 | hSpCas9 | negative selection | 3491504 | 37565576 | 37565599 | 18 | - | 26780180 | A375 | viability (Avana lentiGuide) | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | 3.43124293471895 | [] | [] | 3 | hSpCas9 | negative selection | 3600162 | 37485524 | 37485547 | 18 | - | 26780180 | A375 | viability (Avana lentiGuide) | CGAGCAGAAGACTCTGCCCGGGG | CELF4 | ENSG00000101489 | 3.12586588650778 | [] | [] | 3 | hSpCas9 | negative selection | 3600163 | 37565576 | 37565599 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | -0.40681854033086545 | [4] | [3,2] | -6 | hSpCas9 | positive selection | 3708821 | 37485524 | 37485547 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CGAGCAGAAGACTCTGCCCGGGG | CELF4 | ENSG00000101489 | 0.352429179239503 | [5] | [7,6] | 9 | hSpCas9 | positive selection | 3708822 | 37565576 | 37565599 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACGCAAGCCTCAGTACCAACGGG | CELF4 | ENSG00000101489 | -0.02796501730165893 | [5] | [5,4] | 0 | hSpCas9 | positive selection | 3817428 | 37485524 | 37485547 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CGAGCAGAAGACTCTGCCCGGGG | CELF4 | ENSG00000101489 | 0.07395225631532393 | [6] | [5,5] | 1 | hSpCas9 | positive selection | 3817429 | 37565494 | 37565517 | 18 | - | 26780180 | A375 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.983615086208801 | [] | [] | 4 | hSpCas9 | negative selection | 3925589 | 37485563 | 37485586 | 18 | - | 26780180 | A375 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.547397535681095 | [] | [] | 1 | hSpCas9 | negative selection | 3925590 | 37565521 | 37565544 | 18 | - | 26780180 | A375 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 1.19350612216022 | [] | [] | 6 | hSpCas9 | negative selection | 3925591 | 37485539 | 37485562 | 18 | + | 26780180 | A375 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 1.35274722329338 | [] | [] | 7 | hSpCas9 | negative selection | 3925592 | 37565494 | 37565517 | 18 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 1.21064298863652 | [] | [] | 6 | hSpCas9 | negative selection | 4033555 | 37485563 | 37485586 | 18 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.914921755053632 | [] | [] | 4 | hSpCas9 | negative selection | 4033556 | 37565521 | 37565544 | 18 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 1.55451351431497 | [] | [] | 7 | hSpCas9 | negative selection | 4033557 | 37485539 | 37485562 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.986832517075737 | [] | [] | 4 | hSpCas9 | negative selection | 4033558 | 37565603 | 37565626 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | 0.32867713959587574 | [6] | [5,5] | 7 | hSpCas9 | positive selection | 4126940 | 37565494 | 37565517 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.2832984728656839 | [6] | [5,5] | 7 | hSpCas9 | positive selection | 4126941 | 37485563 | 37485586 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.10403893434074976 | [4] | [2,2] | -2 | hSpCas9 | positive selection | 4126942 | 37485570 | 37485593 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CGCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.5225572108382261 | [5] | [6,3] | 9 | hSpCas9 | positive selection | 4126943 | 37565603 | 37565626 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AGCCTGTCCGTTTGCTAACGTGG | CELF4 | ENSG00000101489 | 1.033437065111199 | [5] | [6,5,5,4] | 7 | hSpCas9 | positive selection | 4190962 | 37565494 | 37565517 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 1.026529200130012 | [6] | [5,6,4,4] | 7 | hSpCas9 | positive selection | 4190963 | 37485563 | 37485586 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.22434847682745968 | [4] | [4,3,1,0] | 1 | hSpCas9 | positive selection | 4190964 | 37485570 | 37485593 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CGCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.013881660793103046 | [5] | [4,3,3,0] | 0 | hSpCas9 | positive selection | 4190965 | 37565494 | 37565517 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.27688357963977756 | [2] | [2,2] | 5 | hSpCas9 | positive selection | 4262712 | 37485539 | 37485562 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.13374588910763746 | [2] | [2,1] | -3 | hSpCas9 | positive selection | 4326985 | 37485563 | 37485586 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.3145212285283998 | [1] | [1,0] | -6 | hSpCas9 | positive selection | 4326986 | 37565521 | 37565544 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.24015499340475588 | [2] | [1,0] | -5 | hSpCas9 | positive selection | 4326987 | 37485571 | 37485593 | 18 | + | 27760321 | OCIAML3 | viability | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | -0.27922208408237276 | [790,705] | [413,569] | -3 | hSpCas9 | negative selection | 4388432 | 37565494 | 37565516 | 18 | - | 27760321 | OCIAML3 | viability | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.32244952124762094 | [727,610] | [557,774] | 4 | hSpCas9 | negative selection | 4388433 | 37565521 | 37565543 | 18 | - | 27760321 | OCIAML3 | viability | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.18411188129958891 | [440,354] | [276,448] | 2 | hSpCas9 | negative selection | 4388434 | 37485571 | 37485593 | 18 | + | 27760321 | OCIAML2 | viability | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.051398275286187456 | [790,705] | [579,687] | 0 | hSpCas9 | negative selection | 4471895 | 37565494 | 37565516 | 18 | - | 27760321 | OCIAML2 | viability | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | -0.3639582425911757 | [727,610] | [451,375] | -4 | hSpCas9 | negative selection | 4471896 | 37565521 | 37565543 | 18 | - | 27760321 | OCIAML2 | viability | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.1613594286252974 | [440,354] | [307,423] | 2 | hSpCas9 | negative selection | 4471897 | 37485571 | 37485593 | 18 | + | 27760321 | MV411 | viability | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.8728986733200885 | [790,705] | [1045,688] | 6 | hSpCas9 | negative selection | 4555358 | 37565494 | 37565516 | 18 | - | 27760321 | MV411 | viability | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 1.051107705075375 | [727,610] | [1044,711] | 7 | hSpCas9 | negative selection | 4555359 | 37565521 | 37565543 | 18 | - | 27760321 | MV411 | viability | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.18200067859086957 | [440,354] | [404,132] | 1 | hSpCas9 | negative selection | 4555360 | 37485571 | 37485593 | 18 | + | 27760321 | HL60 | viability | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.20428855212455121 | [790,705] | [337,1090] | 2 | hSpCas9 | negative selection | 4638821 | 37565494 | 37565516 | 18 | - | 27760321 | HL60 | viability | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.23304908913376166 | [727,610] | [632,647] | 3 | hSpCas9 | negative selection | 4638822 | 37565521 | 37565543 | 18 | - | 27760321 | HL60 | viability | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.9537738871149486 | [440,354] | [682,565] | 8 | hSpCas9 | negative selection | 4638823 | 37485571 | 37485593 | 18 | + | 27760321 | HT1080 | viability | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.7652240964846035 | [705,550] | [415,435] | 4 | hSpCas9 | negative selection | 4722284 | 37565494 | 37565516 | 18 | - | 27760321 | HT1080 | viability | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.5214549245002732 | [610,476] | [259,366] | 2 | hSpCas9 | negative selection | 4722285 | 37565521 | 37565543 | 18 | - | 27760321 | HT1080 | viability | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 2.1686087776690073 | [354,276] | [543,589] | 9 | hSpCas9 | negative selection | 4722286 | 37485571 | 37485593 | 18 | + | 27760321 | HT29 | viability after 7 days | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | -0.07631482398408052 | [705,550] | [875,708,729] | -1 | hSpCas9 | negative selection | 4805747 | 37565494 | 37565516 | 18 | - | 27760321 | HT29 | viability after 7 days | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.15640553160386794 | [610,476] | [901,802,653] | 2 | hSpCas9 | negative selection | 4805748 | 37565521 | 37565543 | 18 | - | 27760321 | HT29 | viability after 7 days | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.36366391632800427 | [354,276] | [387,659,500] | 5 | hSpCas9 | negative selection | 4805749 | 37485571 | 37485593 | 18 | + | 27760321 | HT29 | viability after 25 days | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.14041436343333058 | [705,550] | [787,889,684] | 1 | hSpCas9 | negative selection | 4889210 | 37565494 | 37565516 | 18 | - | 27760321 | HT29 | viability after 25 days | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.2668564453449874 | [610,476] | [727,657,870] | 2 | hSpCas9 | negative selection | 4889211 | 37565521 | 37565543 | 18 | - | 27760321 | HT29 | viability after 25 days | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.144478433513469 | [354,276] | [372,318,518] | 1 | hSpCas9 | negative selection | 4889212 | 37485571 | 37485593 | 18 | + | 27760321 | HT29 | viability after 22 days | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.20813645173821005 | [705,550] | [943,851,717] | 2 | hSpCas9 | negative selection | 4972673 | 37565494 | 37565516 | 18 | - | 27760321 | HT29 | viability after 22 days | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.35133665514428514 | [610,476] | [909,796,695] | 4 | hSpCas9 | negative selection | 4972674 | 37565521 | 37565543 | 18 | - | 27760321 | HT29 | viability after 22 days | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.03935655583658473 | [354,276] | [338,461,264] | 0 | hSpCas9 | negative selection | 4972675 | 37485571 | 37485593 | 18 | + | 27760321 | HT29 | viability after 19 days | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.3306323810072276 | [705,550] | [951,1014,754] | 3 | hSpCas9 | negative selection | 5056136 | 37565494 | 37565516 | 18 | - | 27760321 | HT29 | viability after 19 days | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.4839278448207259 | [610,476] | [854,876,875] | 5 | hSpCas9 | negative selection | 5056137 | 37565521 | 37565543 | 18 | - | 27760321 | HT29 | viability after 19 days | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.2313820105618688 | [354,276] | [460,294,187] | -2 | hSpCas9 | negative selection | 5056138 | 37485571 | 37485593 | 18 | + | 27760321 | HT29 | viability after 16 days | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.05417289516742163 | [705,550] | [799,718,677] | 0 | hSpCas9 | negative selection | 5139599 | 37565494 | 37565516 | 18 | - | 27760321 | HT29 | viability after 16 days | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.46548295122758254 | [610,476] | [736,774,1000] | 5 | hSpCas9 | negative selection | 5139600 | 37565521 | 37565543 | 18 | - | 27760321 | HT29 | viability after 16 days | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.30800801234920416 | [354,276] | [505,491,319] | 3 | hSpCas9 | negative selection | 5139601 | 37485571 | 37485593 | 18 | + | 27760321 | HT29 | viability after 13 days | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.25786335929116766 | [705,550] | [907,916,794] | 3 | hSpCas9 | negative selection | 5223062 | 37565494 | 37565516 | 18 | - | 27760321 | HT29 | viability after 13 days | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.4941265637360538 | [610,476] | [1105,687,872] | 6 | hSpCas9 | negative selection | 5223063 | 37565521 | 37565543 | 18 | - | 27760321 | HT29 | viability after 13 days | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.062435654712221345 | [354,276] | [191,484,374] | 0 | hSpCas9 | negative selection | 5223064 | 37485571 | 37485593 | 18 | + | 27760321 | HT29 | viability after 10 days | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.2789207411222421 | [705,550] | [1139,865,849] | 4 | hSpCas9 | negative selection | 5306525 | 37565494 | 37565516 | 18 | - | 27760321 | HT29 | viability after 10 days | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.2688023296641946 | [610,476] | [525,1111,824] | 3 | hSpCas9 | negative selection | 5306526 | 37565521 | 37565543 | 18 | - | 27760321 | HT29 | viability after 10 days | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.3385025969229084 | [354,276] | [531,733,242] | 4 | hSpCas9 | negative selection | 5306527 | 37485571 | 37485593 | 18 | + | 27760321 | MOLM13 | viability | GCTGACTCACGCTCGCAGTAGG | CELF4 | ENSG00000101489 | 0.6773202591106171 | [790,705] | [816,552] | 5 | hSpCas9 | negative selection | 5389988 | 37565494 | 37565516 | 18 | - | 27760321 | MOLM13 | viability | CCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.6439554878039365 | [727,610] | [702,489] | 4 | hSpCas9 | negative selection | 5389989 | 37565521 | 37565543 | 18 | - | 27760321 | MOLM13 | viability | AACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.9286797482028143 | [440,354] | [726,167] | 6 | hSpCas9 | negative selection | 5389990 | 37565503 | 37565526 | 18 | + | 27661255 | K562 | viability | GAATGGTCGACGGGTTCCCCGGG | CELF4 | ENSG00000101489 | -0.06818968436288175 | [1889,1966] | [1612,1344] | -3 | dCas9-KRAB | negative selection | 5470188 | 37565272 | 37565295 | 18 | - | 27661255 | K562 | viability | GCCGGCCGGCGACTGACGAGCGG | CELF4 | ENSG00000101489 | 0.010967224711691148 | [561,609] | [565,389] | 0 | dCas9-KRAB | negative selection | 5470189 | 37565367 | 37565390 | 18 | - | 27661255 | K562 | viability | GTTCTGAAGGACAGGTTCACAGG | CELF4 | ENSG00000101489 | 0.15625568397217898 | [950,1153] | [951,917] | 5 | dCas9-KRAB | negative selection | 5470190 | 37565538 | 37565561 | 18 | - | 27661255 | K562 | viability | GGCAGTGCCGGGCACATGAACGG | CELF4 | ENSG00000101489 | 0.07381492550304825 | [697,828] | [755,540] | 2 | dCas9-KRAB | negative selection | 5470191 | 37565752 | 37565775 | 18 | - | 27661255 | K562 | viability | GCGAGGTGTAGAGAAACCGAGGG | CELF4 | ENSG00000101489 | 0.5470888992666499 | [329,386] | [420,413] | 9 | dCas9-KRAB | negative selection | 5470192 | 37565806 | 37565829 | 18 | - | 27661255 | K562 | viability | GCGCGAGCGAGCGAGAGAAGAGG | CELF4 | ENSG00000101489 | -0.014401661771122898 | [258,385] | [276,232] | 0 | dCas9-KRAB | negative selection | 5470193 | 37565494 | 37565517 | 18 | - | 27260156 | BXPC3 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.24140234269969485 | [318] | [423,450,270,422] | 5 | hSpCas9 | negative selection | 5535172 | 37485539 | 37485562 | 18 | + | 27260156 | BXPC3 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.04707483734249848 | [398] | [445,427,382,465] | 1 | hSpCas9 | negative selection | 5599445 | 37485563 | 37485586 | 18 | - | 27260156 | BXPC3 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.20415500638680473 | [184] | [117,172,163,227] | -5 | hSpCas9 | negative selection | 5599446 | 37565521 | 37565544 | 18 | - | 27260156 | BXPC3 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.10875749725169537 | [205] | [275,127,201,334] | 2 | hSpCas9 | negative selection | 5599447 | 37565494 | 37565517 | 18 | - | 27260156 | A673 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.1800201611092565 | [318] | [539,285,409,519] | 4 | hSpCas9 | negative selection | 5656423 | 37485539 | 37485562 | 18 | + | 27260156 | A673 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.03469791278357473 | [398] | [578,426,458,415] | -1 | hSpCas9 | negative selection | 5720696 | 37485563 | 37485586 | 18 | - | 27260156 | A673 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.015458638000299674 | [184] | [290,221,203,166] | 0 | hSpCas9 | negative selection | 5720697 | 37565521 | 37565544 | 18 | - | 27260156 | A673 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.03956620083414353 | [205] | [369,138,256,211] | -1 | hSpCas9 | negative selection | 5720698 | 37565494 | 37565517 | 18 | - | 27260156 | A375 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.0619487064774884 | [318] | [439,327,424,356] | 0 | hSpCas9 | negative selection | 5777674 | 37485539 | 37485562 | 18 | + | 27260156 | A375 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.31457808796164594 | [398] | [528,913,448,481] | 4 | hSpCas9 | negative selection | 5841947 | 37485563 | 37485586 | 18 | - | 27260156 | A375 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.020268152766257153 | [184] | [198,247,272,165] | 0 | hSpCas9 | negative selection | 5841948 | 37565521 | 37565544 | 18 | - | 27260156 | A375 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.3888676724992587 | [205] | [346,267,362,278] | 5 | hSpCas9 | negative selection | 5841949 | 37565494 | 37565517 | 18 | - | 27260156 | COLO741 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | -0.17642059979801172 | [318] | [425,374,290] | -4 | hSpCas9 | negative selection | 5898925 | 37485539 | 37485562 | 18 | + | 27260156 | COLO741 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.025413954088010948 | [398] | [569,586,410] | 0 | hSpCas9 | negative selection | 5963198 | 37485563 | 37485586 | 18 | - | 27260156 | COLO741 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.31095706095114206 | [184] | [230,214,132] | -6 | hSpCas9 | negative selection | 5963199 | 37565521 | 37565544 | 18 | - | 27260156 | COLO741 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.12629449016527183 | [205] | [274,171,275] | -3 | hSpCas9 | negative selection | 5963200 | 37565494 | 37565517 | 18 | - | 27260156 | CAL120 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.11135228116715268 | [318] | [462,488,340] | 1 | hSpCas9 | negative selection | 6020176 | 37485539 | 37485562 | 18 | + | 27260156 | CAL120 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.1072335274343105 | [398] | [498,407,480] | -1 | hSpCas9 | negative selection | 6084449 | 37485563 | 37485586 | 18 | - | 27260156 | CAL120 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.4653067033640863 | [184] | [337,389,229] | 7 | hSpCas9 | negative selection | 6084450 | 37565521 | 37565544 | 18 | - | 27260156 | CAL120 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.03354870113547448 | [205] | [286,256,246] | 0 | hSpCas9 | negative selection | 6084451 | 37565494 | 37565517 | 18 | - | 27260156 | CADOES1 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.3971039355168342 | [318] | [482,356,369,350] | 6 | hSpCas9 | negative selection | 6141427 | 37485539 | 37485562 | 18 | + | 27260156 | CADOES1 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.023447709456319216 | [398] | [373,395,286,404] | 0 | hSpCas9 | negative selection | 6205700 | 37485563 | 37485586 | 18 | - | 27260156 | CADOES1 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.16596863540736417 | [184] | [205,230,172,160] | 3 | hSpCas9 | negative selection | 6205701 | 37565521 | 37565544 | 18 | - | 27260156 | CADOES1 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.06216992060746662 | [205] | [210,235,182,168] | 1 | hSpCas9 | negative selection | 6205702 | 37565494 | 37565517 | 18 | - | 27260156 | EWS502 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.03938922593046401 | [318] | [281,388,410,309] | 0 | hSpCas9 | negative selection | 6262678 | 37485539 | 37485562 | 18 | + | 27260156 | EWS502 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.26372216802315335 | [398] | [535,304,634,561] | 4 | hSpCas9 | negative selection | 6326951 | 37485563 | 37485586 | 18 | - | 27260156 | EWS502 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.030735037535361887 | [184] | [121,185,196,312] | 0 | hSpCas9 | negative selection | 6326952 | 37565521 | 37565544 | 18 | - | 27260156 | EWS502 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.60207862543931 | [205] | [160,642,282,236] | 9 | hSpCas9 | negative selection | 6326953 | 37565494 | 37565517 | 18 | - | 27260156 | EW8 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.4639744275190159 | [318] | [471,406,306,260] | 8 | hSpCas9 | negative selection | 6383929 | 37485539 | 37485562 | 18 | + | 27260156 | EW8 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.08810128270988724 | [398] | [396,378,189,279] | -2 | hSpCas9 | negative selection | 6448202 | 37485563 | 37485586 | 18 | - | 27260156 | EW8 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.19191032427459342 | [184] | [140,160,112,113] | -4 | hSpCas9 | negative selection | 6448203 | 37565521 | 37565544 | 18 | - | 27260156 | EW8 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.1938545453504137 | [205] | [157,221,99,112] | -4 | hSpCas9 | negative selection | 6448204 | 37565494 | 37565517 | 18 | - | 27260156 | CORL105 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | -0.006516106263487642 | [318] | [317,351,401,417] | 0 | hSpCas9 | negative selection | 6505180 | 37485539 | 37485562 | 18 | + | 27260156 | CORL105 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.18392980986562613 | [398] | [356,572,805,422] | 3 | hSpCas9 | negative selection | 6569453 | 37485563 | 37485586 | 18 | - | 27260156 | CORL105 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.1855877752696964 | [184] | [166,149,262,192] | -3 | hSpCas9 | negative selection | 6569454 | 37565521 | 37565544 | 18 | - | 27260156 | CORL105 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.07006019407404462 | [205] | [228,208,294,285] | 1 | hSpCas9 | negative selection | 6569455 | 37565494 | 37565517 | 18 | - | 27260156 | HS294T | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.11094696376718982 | [318] | [100,107,165,166] | 1 | hSpCas9 | negative selection | 6626431 | 37485539 | 37485562 | 18 | + | 27260156 | HS294T | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.3091613419927558 | [398] | [116,286,166,197] | 4 | hSpCas9 | negative selection | 6690704 | 37485563 | 37485586 | 18 | - | 27260156 | HS294T | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.7412988851323904 | [184] | [62,244,71,94] | 8 | hSpCas9 | negative selection | 6690705 | 37565521 | 37565544 | 18 | - | 27260156 | HS294T | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.9794616754107603 | [205] | [221,233,83,62] | 9 | hSpCas9 | negative selection | 6690706 | 37565494 | 37565517 | 18 | - | 27260156 | HCC44 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.7005856647828801 | [318] | [541,450,1114,346] | 9 | hSpCas9 | negative selection | 6747682 | 37485539 | 37485562 | 18 | + | 27260156 | HCC44 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.4203600639624325 | [398] | [812,642,543,419] | 7 | hSpCas9 | negative selection | 6811955 | 37485563 | 37485586 | 18 | - | 27260156 | HCC44 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.1811318196930165 | [184] | [300,267,239,142] | 3 | hSpCas9 | negative selection | 6811956 | 37565521 | 37565544 | 18 | - | 27260156 | HCC44 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.1187770221669231 | [205] | [218,165,533,151] | 1 | hSpCas9 | negative selection | 6811957 | 37565494 | 37565517 | 18 | - | 27260156 | G402 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.2301223707334521 | [318] | [397,232,460,698] | 3 | hSpCas9 | negative selection | 6868933 | 37485539 | 37485562 | 18 | + | 27260156 | G402 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.07144205666541573 | [398] | [590,502,223,549] | -1 | hSpCas9 | negative selection | 6933206 | 37485563 | 37485586 | 18 | - | 27260156 | G402 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.5302165321487251 | [184] | [95,200,259,65] | -6 | hSpCas9 | negative selection | 6933207 | 37565521 | 37565544 | 18 | - | 27260156 | G402 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.15607880023504395 | [205] | [149,511,130,318] | 2 | hSpCas9 | negative selection | 6933208 | 37565494 | 37565517 | 18 | - | 27260156 | L33 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.17175882609836196 | [318] | [369,144,256,304] | 4 | hSpCas9 | negative selection | 6990184 | 37485539 | 37485562 | 18 | + | 27260156 | L33 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.06126785113786329 | [398] | [413,131,298,317] | -1 | hSpCas9 | negative selection | 7054457 | 37485563 | 37485586 | 18 | - | 27260156 | L33 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.2182526520348953 | [184] | [100,73,84,219] | -5 | hSpCas9 | negative selection | 7054458 | 37565521 | 37565544 | 18 | - | 27260156 | L33 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.3558517713418077 | [205] | [153,62,143,107] | -7 | hSpCas9 | negative selection | 7054459 | 37565494 | 37565517 | 18 | - | 27260156 | K562 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | -0.2529206925405165 | [318] | [334,77,327,210] | -3 | hSpCas9 | negative selection | 7111435 | 37485539 | 37485562 | 18 | + | 27260156 | K562 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.10881752787562907 | [398] | [362,301,258,382] | -1 | hSpCas9 | negative selection | 7175708 | 37485563 | 37485586 | 18 | - | 27260156 | K562 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.8202653527369492 | [184] | [145,190,548,258] | 9 | hSpCas9 | negative selection | 7175709 | 37565521 | 37565544 | 18 | - | 27260156 | K562 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.671511427175331 | [205] | [211,603,222,150] | 8 | hSpCas9 | negative selection | 7175710 | 37565494 | 37565517 | 18 | - | 27260156 | HT29 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.270187669292545 | [318] | [379,440,585,452] | 5 | hSpCas9 | negative selection | 7232686 | 37485539 | 37485562 | 18 | + | 27260156 | HT29 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.026263252332959203 | [398] | [435,399,498,547] | 0 | hSpCas9 | negative selection | 7296959 | 37485563 | 37485586 | 18 | - | 27260156 | HT29 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.354146334073579 | [184] | [318,457,182,213] | 7 | hSpCas9 | negative selection | 7296960 | 37565521 | 37565544 | 18 | - | 27260156 | HT29 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.09074913717232924 | [205] | [240,380,97,342] | 1 | hSpCas9 | negative selection | 7296961 | 37565494 | 37565517 | 18 | - | 27260156 | MHHES1 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.0808035838435946 | [318] | [574,281,382,302] | 1 | hSpCas9 | negative selection | 7353937 | 37485539 | 37485562 | 18 | + | 27260156 | MHHES1 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.17820380792787727 | [398] | [463,735,443,416] | 3 | hSpCas9 | negative selection | 7418210 | 37485563 | 37485586 | 18 | - | 27260156 | MHHES1 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.09071442325095647 | [184] | [86,346,289,167] | 1 | hSpCas9 | negative selection | 7418211 | 37565521 | 37565544 | 18 | - | 27260156 | MHHES1 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.3347008377461249 | [205] | [398,270,227,278] | 6 | hSpCas9 | negative selection | 7418212 | 37565494 | 37565517 | 18 | - | 27260156 | MEWO | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.5566064598880324 | [318] | [382,422,499] | 9 | hSpCas9 | negative selection | 7475188 | 37485539 | 37485562 | 18 | + | 27260156 | MEWO | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.14476528672261677 | [398] | [407,235,382] | -3 | hSpCas9 | negative selection | 7539461 | 37485563 | 37485586 | 18 | - | 27260156 | MEWO | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.0533003870072446 | [184] | [215,136,192] | 1 | hSpCas9 | negative selection | 7539462 | 37565521 | 37565544 | 18 | - | 27260156 | MEWO | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.3408992663778716 | [205] | [246,118,108] | -6 | hSpCas9 | negative selection | 7539463 | 37565494 | 37565517 | 18 | - | 27260156 | LNCAPCLONEFGC | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.11146508067531491 | [318] | [356,309,279,295] | 1 | hSpCas9 | negative selection | 7596439 | 37485539 | 37485562 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.04598354174587452 | [398] | [364,385,393,258] | 0 | hSpCas9 | negative selection | 7660712 | 37485563 | 37485586 | 18 | - | 27260156 | LNCAPCLONEFGC | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.017009966347637295 | [184] | [122,163,230,154] | 0 | hSpCas9 | negative selection | 7660713 | 37565521 | 37565544 | 18 | - | 27260156 | LNCAPCLONEFGC | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.2432200861347964 | [205] | [172,215,290,214] | 4 | hSpCas9 | negative selection | 7660714 | 37565494 | 37565517 | 18 | - | 27260156 | PANC0327 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.1495505045399439 | [318] | [411,401,311,127] | 2 | hSpCas9 | negative selection | 7717690 | 37485539 | 37485562 | 18 | + | 27260156 | PANC0327 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.06245944484612326 | [398] | [517,341,293,341] | 0 | hSpCas9 | negative selection | 7781963 | 37485563 | 37485586 | 18 | - | 27260156 | PANC0327 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.6523556666010033 | [184] | [377,107,141,433] | 8 | hSpCas9 | negative selection | 7781964 | 37565521 | 37565544 | 18 | - | 27260156 | PANC0327 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.18549856824694344 | [205] | [121,147,141,229] | -3 | hSpCas9 | negative selection | 7781965 | 37565494 | 37565517 | 18 | - | 27260156 | NCIH2009 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.37848245351728077 | [318] | [743,563,461] | 5 | hSpCas9 | negative selection | 7838941 | 37485539 | 37485562 | 18 | + | 27260156 | NCIH2009 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.6452834978594051 | [398] | [974,794,865] | 8 | hSpCas9 | negative selection | 7903214 | 37485563 | 37485586 | 18 | - | 27260156 | NCIH2009 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.24003203990438626 | [184] | [546,252,163] | 3 | hSpCas9 | negative selection | 7903215 | 37565521 | 37565544 | 18 | - | 27260156 | NCIH2009 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.141072249054627 | [205] | [319,378,251] | 2 | hSpCas9 | negative selection | 7903216 | 37565494 | 37565517 | 18 | - | 27260156 | NCIH1373 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.5690876982312585 | [318] | [686,450,387,166] | 5 | hSpCas9 | negative selection | 7960192 | 37485539 | 37485562 | 18 | + | 27260156 | NCIH1373 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.5684177977422246 | [398] | [573,691,982,93] | 5 | hSpCas9 | negative selection | 8024465 | 37485563 | 37485586 | 18 | - | 27260156 | NCIH1373 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.2622103968425813 | [184] | [186,123,532,36] | 2 | hSpCas9 | negative selection | 8024466 | 37565521 | 37565544 | 18 | - | 27260156 | NCIH1373 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.687815339713294 | [205] | [437,277,153,172] | 6 | hSpCas9 | negative selection | 8024467 | 37565494 | 37565517 | 18 | - | 27260156 | PATU8902 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.34706493473352873 | [318] | [591,554,498,634] | 3 | hSpCas9 | negative selection | 8081443 | 37485539 | 37485562 | 18 | + | 27260156 | PATU8902 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.481104353895332 | [398] | [1125,942,430,668] | 5 | hSpCas9 | negative selection | 8145716 | 37485563 | 37485586 | 18 | - | 27260156 | PATU8902 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.32394285282103996 | [184] | [292,349,370,252] | 3 | hSpCas9 | negative selection | 8145717 | 37565521 | 37565544 | 18 | - | 27260156 | PATU8902 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.08815092946148995 | [205] | [239,327,111,461] | -1 | hSpCas9 | negative selection | 8145718 | 37565494 | 37565517 | 18 | - | 27260156 | PANC1 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.28786663695131837 | [318] | [342,367,248,371] | 4 | hSpCas9 | negative selection | 8202694 | 37485539 | 37485562 | 18 | + | 27260156 | PANC1 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.25142982229299893 | [398] | [429,315,379,468] | 4 | hSpCas9 | negative selection | 8266967 | 37485563 | 37485586 | 18 | - | 27260156 | PANC1 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.32259975237460803 | [184] | [219,182,187,196] | 5 | hSpCas9 | negative selection | 8266968 | 37565521 | 37565544 | 18 | - | 27260156 | PANC1 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.6713782208681445 | [205] | [175,456,374,171] | 9 | hSpCas9 | negative selection | 8266969 | 37565494 | 37565517 | 18 | - | 27260156 | PANC0813 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.536817847919166 | [318] | [611,755,516,307] | 8 | hSpCas9 | negative selection | 8323945 | 37485539 | 37485562 | 18 | + | 27260156 | PANC0813 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.3991649250676989 | [398] | [529,722,678,535] | 6 | hSpCas9 | negative selection | 8388218 | 37485563 | 37485586 | 18 | - | 27260156 | PANC0813 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.37107995418121564 | [184] | [96,338,317,348] | 6 | hSpCas9 | negative selection | 8388219 | 37565521 | 37565544 | 18 | - | 27260156 | PANC0813 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.30321026762807524 | [205] | [236,279,484,192] | 5 | hSpCas9 | negative selection | 8388220 | 37565494 | 37565517 | 18 | - | 27260156 | RDES | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | -0.10372910521071299 | [318] | [251,211,371,591] | -2 | hSpCas9 | negative selection | 8445196 | 37485539 | 37485562 | 18 | + | 27260156 | RDES | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.23558445037215076 | [398] | [490,465,605,611] | 4 | hSpCas9 | negative selection | 8509469 | 37485563 | 37485586 | 18 | - | 27260156 | RDES | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.006065640243383852 | [184] | [193,234,181,232] | 0 | hSpCas9 | negative selection | 8509470 | 37565521 | 37565544 | 18 | - | 27260156 | RDES | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.3806654197068218 | [205] | [294,231,303,419] | 6 | hSpCas9 | negative selection | 8509471 | 37565494 | 37565517 | 18 | - | 27260156 | PC3 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.11869125511493 | [318] | [300,387,418,268] | 2 | hSpCas9 | negative selection | 8566447 | 37485539 | 37485562 | 18 | + | 27260156 | PC3 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.27149322408530796 | [398] | [253,242,560,350] | -6 | hSpCas9 | negative selection | 8630720 | 37485563 | 37485586 | 18 | - | 27260156 | PC3 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.008503928119742987 | [184] | [103,327,167,142] | 0 | hSpCas9 | negative selection | 8630721 | 37565521 | 37565544 | 18 | - | 27260156 | PC3 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.6675339186001147 | [205] | [196,297,495,410] | 9 | hSpCas9 | negative selection | 8630722 | 37565494 | 37565517 | 18 | - | 27260156 | PATU8988T | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.2305153860599552 | [318] | [328,326,213,593] | 4 | hSpCas9 | negative selection | 8687698 | 37485539 | 37485562 | 18 | + | 27260156 | PATU8988T | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.22168590602819618 | [398] | [404,470,336,600] | 4 | hSpCas9 | negative selection | 8751971 | 37485563 | 37485586 | 18 | - | 27260156 | PATU8988T | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.14124723691722307 | [184] | [178,169,200,92] | -2 | hSpCas9 | negative selection | 8751972 | 37565521 | 37565544 | 18 | - | 27260156 | PATU8988T | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.3774344526429312 | [205] | [229,326,138,353] | 6 | hSpCas9 | negative selection | 8751973 | 37565494 | 37565517 | 18 | - | 27260156 | T47D | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.1552964594893625 | [318] | [427,426,358,441] | 3 | hSpCas9 | negative selection | 8808949 | 37485539 | 37485562 | 18 | + | 27260156 | T47D | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.15092117983581774 | [398] | [457,406,373,437] | -3 | hSpCas9 | negative selection | 8873222 | 37485563 | 37485586 | 18 | - | 27260156 | T47D | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.1626470893892631 | [184] | [222,191,218,133] | -4 | hSpCas9 | negative selection | 8873223 | 37565521 | 37565544 | 18 | - | 27260156 | T47D | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.06837197776407478 | [205] | [213,269,256,263] | 1 | hSpCas9 | negative selection | 8873224 | 37565494 | 37565517 | 18 | - | 27260156 | SU8686 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.35666382010750847 | [318] | [243,334,435,673] | 6 | hSpCas9 | negative selection | 8930200 | 37485539 | 37485562 | 18 | + | 27260156 | SU8686 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.1592998150228569 | [398] | [408,373,395,625] | 2 | hSpCas9 | negative selection | 8994473 | 37485563 | 37485586 | 18 | - | 27260156 | SU8686 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.4881943064251524 | [184] | [207,200,342,296] | 7 | hSpCas9 | negative selection | 8994474 | 37565521 | 37565544 | 18 | - | 27260156 | SU8686 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.11210077834349441 | [205] | [208,198,235,245] | 1 | hSpCas9 | negative selection | 8994475 | 37565494 | 37565517 | 18 | - | 27260156 | SKES1 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.008838178580956924 | [318] | [257,460,251,315] | 0 | hSpCas9 | negative selection | 9051451 | 37485539 | 37485562 | 18 | + | 27260156 | SKES1 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.05128777820757649 | [398] | [348,396,441,344] | -1 | hSpCas9 | negative selection | 9115724 | 37485563 | 37485586 | 18 | - | 27260156 | SKES1 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.382781534573408 | [184] | [128,190,114,134] | -7 | hSpCas9 | negative selection | 9115725 | 37565521 | 37565544 | 18 | - | 27260156 | SKES1 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.3055505891861703 | [205] | [264,308,244,207] | 6 | hSpCas9 | negative selection | 9115726 | 37565494 | 37565517 | 18 | - | 27260156 | TOV112D | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.12120470067375866 | [318] | [426,283,340,328] | 2 | hSpCas9 | negative selection | 9172702 | 37485539 | 37485562 | 18 | + | 27260156 | TOV112D | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.0031440329388692234 | [398] | [289,766,335,285] | 0 | hSpCas9 | negative selection | 9236975 | 37485563 | 37485586 | 18 | - | 27260156 | TOV112D | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | 0.03205380307650185 | [184] | [160,180,184,224] | 0 | hSpCas9 | negative selection | 9236976 | 37565521 | 37565544 | 18 | - | 27260156 | TOV112D | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.0677835434885139 | [205] | [352,230,232,66] | 1 | hSpCas9 | negative selection | 9236977 | 37565494 | 37565517 | 18 | - | 27260156 | TC71 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | 0.07553456364738242 | [318] | [383,340,304,415] | 2 | hSpCas9 | negative selection | 9293953 | 37485539 | 37485562 | 18 | + | 27260156 | TC71 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | -0.12316936021899003 | [398] | [311,479,295,493] | -3 | hSpCas9 | negative selection | 9358226 | 37485563 | 37485586 | 18 | - | 27260156 | TC71 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.13238558430904313 | [184] | [163,175,175,209] | -3 | hSpCas9 | negative selection | 9358227 | 37565521 | 37565544 | 18 | - | 27260156 | TC71 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | -0.26026619964685116 | [205] | [137,219,196,182] | -6 | hSpCas9 | negative selection | 9358228 | 37565494 | 37565517 | 18 | - | 27260156 | TC32 | viability | CCCGTCGACCATTCCCATGAAGG | CELF4 | ENSG00000101489 | -0.03238334051639935 | [318] | [218,362,252,292] | 0 | hSpCas9 | negative selection | 9415204 | 37485539 | 37485562 | 18 | + | 27260156 | TC32 | viability | TCTGCTCGTGCAGCGCGCTCTGG | CELF4 | ENSG00000101489 | 0.3782694505132796 | [398] | [563,324,663,446] | 6 | hSpCas9 | negative selection | 9479477 | 37485563 | 37485586 | 18 | - | 27260156 | TC32 | viability | CGAGCGTGAGTCAGCGCTGAAGG | CELF4 | ENSG00000101489 | -0.307714918516804 | [184] | [145,59,116,263] | -5 | hSpCas9 | negative selection | 9479478 | 37565521 | 37565544 | 18 | - | 27260156 | TC32 | viability | GAACGGATTAAGCCACAGCCCGG | CELF4 | ENSG00000101489 | 0.40093376003704095 | [205] | [246,277,262,207] | 7 | hSpCas9 | negative selection | 9479479 | 37273121 | 37273144 | 18 | - | 27869803 | HPAFII | viability after 27 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 1.3954568213148544 | [144] | [181,215,NaN] | 9 | hSpCas9 | negative selection | 9564531 | 37321790 | 37321813 | 18 | + | 27869803 | HPAFII | viability after 27 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 0.05146348357808006 | [145] | [54,99,NaN] | 0 | hSpCas9 | negative selection | 9564532 | 37485579 | 37485602 | 18 | + | 27869803 | HPAFII | viability after 27 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 1.2597699945457443 | [269] | [310,363,NaN] | 8 | hSpCas9 | negative selection | 9564533 | 37565519 | 37565542 | 18 | - | 27869803 | HPAFII | viability after 27 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.643578212575523 | [435] | [452,278,NaN] | 5 | hSpCas9 | negative selection | 9564534 | 37273121 | 37273144 | 18 | - | 27869803 | HPAFII | viability after 15 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.6843152762794973 | [144] | [271,236,NaN] | 7 | hSpCas9 | negative selection | 9646980 | 37321790 | 37321813 | 18 | + | 27869803 | HPAFII | viability after 15 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.3139924310993675 | [145] | [169,98,NaN] | -4 | hSpCas9 | negative selection | 9646981 | 37485579 | 37485602 | 18 | + | 27869803 | HPAFII | viability after 15 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.6987013662355362 | [269] | [330,557,NaN] | 7 | hSpCas9 | negative selection | 9646982 | 37565519 | 37565542 | 18 | - | 27869803 | HPAFII | viability after 15 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.0940079651517044 | [435] | [665,396,NaN] | 1 | hSpCas9 | negative selection | 9646983 | 37273121 | 37273144 | 18 | - | 27869803 | ASPC1 | viability after 36 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.2714789139835471 | [474] | [157,181,241] | 2 | hSpCas9 | negative selection | 9729429 | 37321790 | 37321813 | 18 | + | 27869803 | ASPC1 | viability after 36 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | -0.5948730083852382 | [341] | [45,8,156] | -5 | hSpCas9 | negative selection | 9729430 | 37485579 | 37485602 | 18 | + | 27869803 | ASPC1 | viability after 36 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | -0.42283809929773863 | [702] | [366,128,94] | -4 | hSpCas9 | negative selection | 9729431 | 37565519 | 37565542 | 18 | - | 27869803 | ASPC1 | viability after 36 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | -0.7063223751121159 | [977] | [112,219,265] | -6 | hSpCas9 | negative selection | 9729432 | 37273121 | 37273144 | 18 | - | 27869803 | PATU8988S | viability after 35 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.15482618972807044 | [368] | [143,186,NaN] | 1 | hSpCas9 | negative selection | 9811878 | 37321790 | 37321813 | 18 | + | 27869803 | PATU8988S | viability after 35 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 0.9953461949431136 | [268] | [207,223,NaN] | 8 | hSpCas9 | negative selection | 9811879 | 37485579 | 37485602 | 18 | + | 27869803 | PATU8988S | viability after 35 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.5225856036336145 | [701] | [252,559,NaN] | 6 | hSpCas9 | negative selection | 9811880 | 37565519 | 37565542 | 18 | - | 27869803 | PATU8988S | viability after 35 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.21878011309483492 | [984] | [535,386,NaN] | 2 | hSpCas9 | negative selection | 9811881 | 37273121 | 37273144 | 18 | - | 27869803 | PATU8988S | viability after 31 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.724906201915809 | [368] | [174,329,NaN] | 8 | hSpCas9 | negative selection | 9894327 | 37321790 | 37321813 | 18 | + | 27869803 | PATU8988S | viability after 31 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 1.2795477521809804 | [268] | [222,307,NaN] | 9 | hSpCas9 | negative selection | 9894328 | 37485579 | 37485602 | 18 | + | 27869803 | PATU8988S | viability after 31 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 0.3808835623439916 | [701] | [228,536,NaN] | 4 | hSpCas9 | negative selection | 9894329 | 37565519 | 37565542 | 18 | - | 27869803 | PATU8988S | viability after 31 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.0933873999064464 | [984] | [356,497,NaN] | 1 | hSpCas9 | negative selection | 9894330 | 37273121 | 37273144 | 18 | - | 27869803 | HPAFII | viability after 35 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.9531709253502472 | [144] | [151,130,NaN] | 6 | hSpCas9 | negative selection | 9976776 | 37321790 | 37321813 | 18 | + | 27869803 | HPAFII | viability after 35 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 0.15654574326912607 | [145] | [24,146,NaN] | 1 | hSpCas9 | negative selection | 9976777 | 37485579 | 37485602 | 18 | + | 27869803 | HPAFII | viability after 35 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 1.3039237176742795 | [269] | [233,453,NaN] | 8 | hSpCas9 | negative selection | 9976778 | 37565519 | 37565542 | 18 | - | 27869803 | HPAFII | viability after 35 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.5938304650099129 | [435] | [350,312,NaN] | 4 | hSpCas9 | negative selection | 9976779 | 37273121 | 37273144 | 18 | - | 27869803 | HPAFII | viability after 31 days | CCTGATGGCATCAGTCGCGCAGG | CELF4 | ENSG00000101489 | 0.7216261808179228 | [144] | [104,165,NaN] | 5 | hSpCas9 | negative selection | 10059225 | 37321790 | 37321813 | 18 | + | 27869803 | HPAFII | viability after 31 days | AGTGGGCCCTCACGTGAAGGGGG | CELF4 | ENSG00000101489 | 0.5334199494344388 | [145] | [75,164,NaN] | 4 | hSpCas9 | negative selection | 10059226 | 37485579 | 37485602 | 18 | + | 27869803 | HPAFII | viability after 31 days | ACGCTCGCAGTAGGTGAGGAAGG | CELF4 | ENSG00000101489 | 1.3514933083007008 | [269] | [367,406,NaN] | 8 | hSpCas9 | negative selection | 10059227 | 37565519 | 37565542 | 18 | - | 27869803 | HPAFII | viability after 31 days | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.7503110830447899 | [435] | [480,335,NaN] | 5 | hSpCas9 | negative selection | 10059228 | 37321835 | 37321858 | 18 | - | 28162770 | P31FUJ | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.7320939946297054 | [103] | [202] | 8 | hSpCas9 | negative selection | 10131462 | 37270884 | 37270907 | 18 | + | 28162770 | P31FUJ | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.36137882633615637 | [207] | [313] | 4 | hSpCas9 | negative selection | 10131463 | 37264701 | 37264724 | 18 | + | 28162770 | P31FUJ | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.707404257693029 | [238] | [42] | -9 | hSpCas9 | negative selection | 10131464 | 37565542 | 37565565 | 18 | + | 28162770 | P31FUJ | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.5196443765408361 | [481] | [811] | 6 | hSpCas9 | negative selection | 10131465 | 37565519 | 37565542 | 18 | - | 28162770 | P31FUJ | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.08980146765268504 | [426] | [533] | 0 | hSpCas9 | negative selection | 10131466 | 37321835 | 37321858 | 18 | - | 28162770 | TF1 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | NaN | [NaN] | [104] | 1 | hSpCas9 | negative selection | 10300828 | 37270884 | 37270907 | 18 | + | 28162770 | TF1 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | NaN | [NaN] | [206] | 1 | hSpCas9 | negative selection | 10300829 | 37264701 | 37264724 | 18 | + | 28162770 | TF1 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | NaN | [NaN] | [80] | 1 | hSpCas9 | negative selection | 10300830 | 37565542 | 37565565 | 18 | + | 28162770 | TF1 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | NaN | [NaN] | [541] | 1 | hSpCas9 | negative selection | 10300831 | 37565519 | 37565542 | 18 | - | 28162770 | TF1 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | NaN | [NaN] | [467] | 1 | hSpCas9 | negative selection | 10300832 | 37321835 | 37321858 | 18 | - | 28162770 | SKM1 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 1.0259952085329442 | [9] | [35] | 8 | hSpCas9 | negative selection | 10470194 | 37270884 | 37270907 | 18 | + | 28162770 | SKM1 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.289506617194985 | [55] | [120] | 3 | hSpCas9 | negative selection | 10470195 | 37264701 | 37264724 | 18 | + | 28162770 | SKM1 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.9649596518640484 | [52] | [11] | -9 | hSpCas9 | negative selection | 10470196 | 37565542 | 37565565 | 18 | + | 28162770 | SKM1 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | -0.06623850840167322 | [121] | [205] | 0 | hSpCas9 | negative selection | 10470197 | 37565519 | 37565542 | 18 | - | 28162770 | SKM1 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.43018532557479594 | [88] | [211] | 4 | hSpCas9 | negative selection | 10470198 | 37321835 | 37321858 | 18 | - | 28162770 | SKM1 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 1.0259952085329442 | [9] | [35] | 8 | hSpCas9 | negative selection | 10639560 | 37270884 | 37270907 | 18 | + | 28162770 | SKM1 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.289506617194985 | [55] | [120] | 3 | hSpCas9 | negative selection | 10639561 | 37264701 | 37264724 | 18 | + | 28162770 | SKM1 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.9649596518640484 | [52] | [11] | -9 | hSpCas9 | negative selection | 10639562 | 37565542 | 37565565 | 18 | + | 28162770 | SKM1 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | -0.06623850840167322 | [121] | [205] | 0 | hSpCas9 | negative selection | 10639563 | 37565519 | 37565542 | 18 | - | 28162770 | SKM1 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.43018532557479594 | [88] | [211] | 4 | hSpCas9 | negative selection | 10639564 | 37321835 | 37321858 | 18 | - | 28162770 | PL21 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.6582458356600498 | [98] | [67] | 5 | hSpCas9 | negative selection | 10808926 | 37270884 | 37270907 | 18 | + | 28162770 | PL21 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | -0.3303751022094597 | [181] | [62] | -2 | hSpCas9 | negative selection | 10808927 | 37264701 | 37264724 | 18 | + | 28162770 | PL21 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -0.9311049187889324 | [183] | [41] | -6 | hSpCas9 | negative selection | 10808928 | 37565542 | 37565565 | 18 | + | 28162770 | PL21 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.21234867218453746 | [352] | [177] | 2 | hSpCas9 | negative selection | 10808929 | 37565519 | 37565542 | 18 | - | 28162770 | PL21 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.47410358048137313 | [262] | [158] | 4 | hSpCas9 | negative selection | 10808930 | 37321835 | 37321858 | 18 | - | 28162770 | P31FUJ | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.7320939946297054 | [103] | [202] | 8 | hSpCas9 | negative selection | 10978292 | 37270884 | 37270907 | 18 | + | 28162770 | P31FUJ | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.36137882633615637 | [207] | [313] | 4 | hSpCas9 | negative selection | 10978293 | 37264701 | 37264724 | 18 | + | 28162770 | P31FUJ | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.707404257693029 | [238] | [42] | -9 | hSpCas9 | negative selection | 10978294 | 37565542 | 37565565 | 18 | + | 28162770 | P31FUJ | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.5196443765408361 | [481] | [811] | 6 | hSpCas9 | negative selection | 10978295 | 37565519 | 37565542 | 18 | - | 28162770 | P31FUJ | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.08980146765268504 | [426] | [533] | 0 | hSpCas9 | negative selection | 10978296 | 37321835 | 37321858 | 18 | - | 28162770 | OCIAML5 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 1.0166888958577505 | [22] | [83] | 8 | hSpCas9 | negative selection | 11147658 | 37270884 | 37270907 | 18 | + | 28162770 | OCIAML5 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.5381675374142743 | [65] | [172] | 5 | hSpCas9 | negative selection | 11147659 | 37264701 | 37264724 | 18 | + | 28162770 | OCIAML5 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.811424586366651 | [139] | [35] | -8 | hSpCas9 | negative selection | 11147660 | 37565542 | 37565565 | 18 | + | 28162770 | OCIAML5 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 1.1364115592407837 | [219] | [872] | 8 | hSpCas9 | negative selection | 11147661 | 37565519 | 37565542 | 18 | - | 28162770 | OCIAML5 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.15376250793820034 | [246] | [495] | 1 | hSpCas9 | negative selection | 11147662 | 37321835 | 37321858 | 18 | - | 28162770 | EOL1 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.5602733859735773 | [120] | [93] | 5 | hSpCas9 | negative selection | 11317024 | 37270884 | 37270907 | 18 | + | 28162770 | EOL1 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.7433780129605996 | [321] | [283] | 6 | hSpCas9 | negative selection | 11317025 | 37264701 | 37264724 | 18 | + | 28162770 | EOL1 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.0244682997106604 | [277] | [35] | -8 | hSpCas9 | negative selection | 11317026 | 37565542 | 37565565 | 18 | + | 28162770 | EOL1 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 1.0160927134473607 | [518] | [552] | 8 | hSpCas9 | negative selection | 11317027 | 37565519 | 37565542 | 18 | - | 28162770 | EOL1 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.24647586645789699 | [447] | [279] | 2 | hSpCas9 | negative selection | 11317028 | 37321835 | 37321858 | 18 | - | 28162770 | MOLM13 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.603950931120607 | [90] | [99] | 4 | hSpCas9 | negative selection | 11486390 | 37270884 | 37270907 | 18 | + | 28162770 | MOLM13 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 1.3779080147069136 | [214] | [403] | 9 | hSpCas9 | negative selection | 11486391 | 37264701 | 37264724 | 18 | + | 28162770 | MOLM13 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -3.3304767572857705 | [319] | [22] | -8 | hSpCas9 | negative selection | 11486392 | 37565542 | 37565565 | 18 | + | 28162770 | MOLM13 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | -0.050511955502099415 | [592] | [413] | 0 | hSpCas9 | negative selection | 11486393 | 37565519 | 37565542 | 18 | - | 28162770 | MOLM13 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.40479254621953675 | [443] | [424] | 3 | hSpCas9 | negative selection | 11486394 | 37321835 | 37321858 | 18 | - | 28162770 | HEL | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 1.309315098275165 | [62] | [99] | 9 | hSpCas9 | negative selection | 11655756 | 37270884 | 37270907 | 18 | + | 28162770 | HEL | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 1.4421009633044304 | [180] | [314] | 9 | hSpCas9 | negative selection | 11655757 | 37264701 | 37264724 | 18 | + | 28162770 | HEL | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -1.9065997589900778 | [239] | [40] | -7 | hSpCas9 | negative selection | 11655758 | 37565542 | 37565565 | 18 | + | 28162770 | HEL | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.18021240694019391 | [349] | [253] | 1 | hSpCas9 | negative selection | 11655759 | 37565519 | 37565542 | 18 | - | 28162770 | HEL | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.5949631074309432 | [306] | [296] | 5 | hSpCas9 | negative selection | 11655760 | 37321835 | 37321858 | 18 | - | 28162770 | MV411 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.6202468146723218 | [77] | [100] | 5 | hSpCas9 | negative selection | 11825122 | 37270884 | 37270907 | 18 | + | 28162770 | MV411 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.6755312028870656 | [109] | [147] | 6 | hSpCas9 | negative selection | 11825123 | 37264701 | 37264724 | 18 | + | 28162770 | MV411 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -1.5472435412397183 | [169] | [48] | -7 | hSpCas9 | negative selection | 11825124 | 37565542 | 37565565 | 18 | + | 28162770 | MV411 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.4269385544664194 | [316] | [358] | 4 | hSpCas9 | negative selection | 11825125 | 37565519 | 37565542 | 18 | - | 28162770 | MV411 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.11149005275357804 | [277] | [252] | 0 | hSpCas9 | negative selection | 11825126 | 37321835 | 37321858 | 18 | - | 28162770 | MONOMAC1 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 2.156600107555147 | [71] | [367] | 9 | hSpCas9 | negative selection | 11994488 | 37270884 | 37270907 | 18 | + | 28162770 | MONOMAC1 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.8759425982975518 | [105] | [222] | 7 | hSpCas9 | negative selection | 11994489 | 37264701 | 37264724 | 18 | + | 28162770 | MONOMAC1 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -0.4025059653595332 | [112] | [97] | -3 | hSpCas9 | negative selection | 11994490 | 37565542 | 37565565 | 18 | + | 28162770 | MONOMAC1 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | -0.005812443816784807 | [253] | [289] | 0 | hSpCas9 | negative selection | 11994491 | 37565519 | 37565542 | 18 | - | 28162770 | MONOMAC1 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.5475823196500874 | [187] | [314] | 5 | hSpCas9 | negative selection | 11994492 | 37321835 | 37321858 | 18 | - | 28162770 | OCIAML2 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 0.24361569242396142 | [15] | [104] | 2 | hSpCas9 | negative selection | 12163854 | 37270884 | 37270907 | 18 | + | 28162770 | OCIAML2 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | -0.17995266433923862 | [27] | [136] | -1 | hSpCas9 | negative selection | 12163855 | 37264701 | 37264724 | 18 | + | 28162770 | OCIAML2 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -2.148701730354799 | [19] | [24] | -8 | hSpCas9 | negative selection | 12163856 | 37565542 | 37565565 | 18 | + | 28162770 | OCIAML2 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | 0.2975544995347651 | [63] | [435] | 3 | hSpCas9 | negative selection | 12163857 | 37565519 | 37565542 | 18 | - | 28162770 | OCIAML2 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.6515984341688547 | [40] | [356] | 6 | hSpCas9 | negative selection | 12163858 | 37321835 | 37321858 | 18 | - | 28162770 | OCIAML3 | viability | CCTGCGGACAGCGAGAGCCGAGG | CELF4 | ENSG00000101489 | 3.365653430539523 | [16] | [528] | 9 | hSpCas9 | negative selection | 12333220 | 37270884 | 37270907 | 18 | + | 28162770 | OCIAML3 | viability | GCTGGTGCAGTGATGCCCGGAGG | CELF4 | ENSG00000101489 | 0.9420452599160467 | [34] | [202] | 7 | hSpCas9 | negative selection | 12333221 | 37264701 | 37264724 | 18 | + | 28162770 | OCIAML3 | viability | GAGGCGGCTGAGGAAAGGCCTGG | CELF4 | ENSG00000101489 | -0.9626522341185557 | [50] | [78] | -6 | hSpCas9 | negative selection | 12333222 | 37565542 | 37565565 | 18 | + | 28162770 | OCIAML3 | viability | TCATGTGCCCGGCACTGCCCGGG | CELF4 | ENSG00000101489 | -0.03733418403443056 | [102] | [302] | 0 | hSpCas9 | negative selection | 12333223 | 37565519 | 37565542 | 18 | - | 28162770 | OCIAML3 | viability | ACGGATTAAGCCACAGCCCGGGG | CELF4 | ENSG00000101489 | 0.7701486899524966 | [100] | [519] | 7 | hSpCas9 | negative selection | 12333224 |