Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1951
• Symbol:CELSR3
• Description:cadherin EGF LAG seven-pass G-type receptor 3

DataSource: http://genomecrispr.dkfz.de/#!/results/CELSR3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48650902	48650925	3	+	26472758	Jiyoye	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.3680755618169329	[186]	[181]	2	hSpCas9	negative selection	29734
48661690	48661713	3	+	26472758	Jiyoye	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	-0.44082152504907646	[62]	[34]	-3	hSpCas9	negative selection	29735
48647954	48647977	3	-	26472758	Jiyoye	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	0.4071753815058735	[156]	[156]	3	hSpCas9	negative selection	29736
48643652	48643675	3	+	26472758	Jiyoye	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.5647166584923533	[77]	[86]	4	hSpCas9	negative selection	29737
48642783	48642806	3	+	26472758	Jiyoye	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-0.4881272398274333	[92]	[49]	-4	hSpCas9	negative selection	29738
48640449	48640472	3	+	26472758	Jiyoye	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-1.0333972098801079	[75]	[27]	-6	hSpCas9	negative selection	29739
48639900	48639923	3	-	26472758	Jiyoye	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-4.236680808268852	[49]	[1]	-9	hSpCas9	negative selection	29740
48662462	48662485	3	-	26472758	Jiyoye	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.2551722880608236	[19]	[17]	2	hSpCas9	negative selection	29741
48662060	48662083	3	-	26472758	Jiyoye	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	-0.18610238742728658	[260]	[172]	-1	hSpCas9	negative selection	29742
48661767	48661790	3	+	26472758	Jiyoye	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	29743
48650902	48650925	3	+	26472758	KBM7	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	-0.19861081624725482	[638,632]	[266,256]	-2	hSpCas9	negative selection	220852
48661690	48661713	3	+	26472758	KBM7	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	0.49308517643872585	[221,108]	[82,126]	5	hSpCas9	negative selection	220853
48647954	48647977	3	-	26472758	KBM7	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-0.5494702425469985	[666,322]	[207,105]	-5	hSpCas9	negative selection	220854
48643652	48643675	3	+	26472758	KBM7	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.1319409784586525	[365,285]	[238,101]	1	hSpCas9	negative selection	220855
48642783	48642806	3	+	26472758	KBM7	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	1.5684244301096348	[195,137]	[269,193]	9	hSpCas9	negative selection	220856
48640449	48640472	3	+	26472758	KBM7	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	0.9860446764207236	[232,131]	[137,190]	9	hSpCas9	negative selection	220857
48639900	48639923	3	-	26472758	KBM7	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-0.988208305090772	[83,83]	[0,36]	-6	hSpCas9	negative selection	220858
48662462	48662485	3	-	26472758	KBM7	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.42148701174433595	[315,266]	[52,298]	4	hSpCas9	negative selection	220859
48662060	48662083	3	-	26472758	KBM7	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.8942981690310698	[956,1153]	[751,1099]	8	hSpCas9	negative selection	220860
48661767	48661790	3	+	26472758	KBM7	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-2.3944707262104954	[25,30]	[0,3]	-9	hSpCas9	negative selection	220861
48650902	48650925	3	+	26472758	Raji	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.7249138985511863	[291]	[111]	6	hSpCas9	negative selection	411970
48661690	48661713	3	+	26472758	Raji	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	-0.5727361983878965	[140]	[21]	-4	hSpCas9	negative selection	411971
48647954	48647977	3	-	26472758	Raji	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	0.08852450812228374	[307]	[75]	0	hSpCas9	negative selection	411972
48643652	48643675	3	+	26472758	Raji	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.3637232886333851	[143]	[42]	3	hSpCas9	negative selection	411973
48642783	48642806	3	+	26472758	Raji	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	1.2954558835261714	[78]	[44]	9	hSpCas9	negative selection	411974
48640449	48640472	3	+	26472758	Raji	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	1.2029611953558306	[72]	[38]	9	hSpCas9	negative selection	411975
48639900	48639923	3	-	26472758	Raji	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-2.26185027429212	[61]	[2]	-9	hSpCas9	negative selection	411976
48662462	48662485	3	-	26472758	Raji	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.8689787960485205	[150]	[63]	7	hSpCas9	negative selection	411977
48662060	48662083	3	-	26472758	Raji	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.10469444784595949	[536]	[133]	1	hSpCas9	negative selection	411978
48661767	48661790	3	+	26472758	Raji	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-1.5930561827674934	[12]	[0]	-8	hSpCas9	negative selection	411979
48650902	48650925	3	+	26472758	K562	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.19113530376815369	[523]	[504]	1	hSpCas9	negative selection	603088
48661690	48661713	3	+	26472758	K562	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	0.15770709447311604	[119]	[112]	1	hSpCas9	negative selection	603089
48647954	48647977	3	-	26472758	K562	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-2.0775093672209155	[404]	[80]	-7	hSpCas9	negative selection	603090
48643652	48643675	3	+	26472758	K562	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	-0.21991406786917067	[257]	[186]	-1	hSpCas9	negative selection	603091
48642783	48642806	3	+	26472758	K562	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	1.1293422032197542	[149]	[276]	8	hSpCas9	negative selection	603092
48640449	48640472	3	+	26472758	K562	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-1.008796617136901	[204]	[85]	-5	hSpCas9	negative selection	603093
48639900	48639923	3	-	26472758	K562	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-0.3836124949465951	[84]	[54]	-3	hSpCas9	negative selection	603094
48662462	48662485	3	-	26472758	K562	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.5778424613916386	[199]	[251]	5	hSpCas9	negative selection	603095
48662060	48662083	3	-	26472758	K562	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	-0.07426370771726121	[887]	[711]	0	hSpCas9	negative selection	603096
48661767	48661790	3	+	26472758	K562	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-4.799975391692006	[32]	[0]	-9	hSpCas9	negative selection	603097
48655114	48655137	3	-	26627737	DLD1	viability	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.8429468572914446	[596]	[126,102,84]	-7	hSpCas9	negative selection	822131
48655376	48655399	3	+	26627737	DLD1	viability	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	0.9566171671858676	[85]	[127,1,27]	8	hSpCas9	negative selection	822132
48655833	48655856	3	+	26627737	DLD1	viability	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.5376145637886667	[1848]	[640,1114,781]	5	hSpCas9	negative selection	822133
48656183	48656206	3	+	26627737	DLD1	viability	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	0.3761299642625924	[251]	[20,195,94]	4	hSpCas9	negative selection	822134
48656893	48656916	3	+	26627737	DLD1	viability	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.6494921382627641	[555]	[248,343,233]	6	hSpCas9	negative selection	822135
48661925	48661948	3	+	26627737	DLD1	viability	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.5387339770155053	[924]	[244,121,222]	-5	hSpCas9	negative selection	822136
48655114	48655137	3	-	26627737	GBM cells	viability after 5 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.24329682060074384	[203]	[115,142]	4	hSpCas9	negative selection	904446
48655376	48655399	3	+	26627737	GBM cells	viability after 5 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-4.045944570921853	[76]	[0,3]	-9	hSpCas9	negative selection	904447
48655833	48655856	3	+	26627737	GBM cells	viability after 5 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.05795056018526168	[797]	[477,412]	0	hSpCas9	negative selection	904448
48656183	48656206	3	+	26627737	GBM cells	viability after 5 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-1.315824973907327	[187]	[34,45]	-9	hSpCas9	negative selection	904449
48656893	48656916	3	+	26627737	GBM cells	viability after 5 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.18505364098227184	[350]	[181,245]	3	hSpCas9	negative selection	904450
48661925	48661948	3	+	26627737	GBM cells	viability after 5 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.28373943139954916	[369]	[165,159]	-4	hSpCas9	negative selection	904451
48655114	48655137	3	-	26627737	GBM cells	viability after 13 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.39082437325373576	[203]	[95,74]	-5	hSpCas9	negative selection	986761
48655376	48655399	3	+	26627737	GBM cells	viability after 13 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-1.7189295091878383	[76]	[15,9]	-9	hSpCas9	negative selection	986762
48655833	48655856	3	+	26627737	GBM cells	viability after 13 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.23344255497549615	[797]	[481,530]	3	hSpCas9	negative selection	986763
48656183	48656206	3	+	26627737	GBM cells	viability after 13 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.8990555870107065	[187]	[73,38]	-8	hSpCas9	negative selection	986764
48656893	48656916	3	+	26627737	GBM cells	viability after 13 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.29087098881614204	[350]	[275,197]	4	hSpCas9	negative selection	986765
48661925	48661948	3	+	26627737	GBM cells	viability after 13 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-1.009671620164498	[369]	[134,70]	-8	hSpCas9	negative selection	986766
48655114	48655137	3	-	26627737	GBM cells	viability after 21 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.36146073597184813	[203]	[79,91]	-3	hSpCas9	negative selection	1069076
48655376	48655399	3	+	26627737	GBM cells	viability after 21 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-0.5525387568334992	[76]	[27,28]	-5	hSpCas9	negative selection	1069077
48655833	48655856	3	+	26627737	GBM cells	viability after 21 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.3874759757158701	[797]	[587,547]	4	hSpCas9	negative selection	1069078
48656183	48656206	3	+	26627737	GBM cells	viability after 21 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-1.635802311292586	[187]	[35,29]	-8	hSpCas9	negative selection	1069079
48656893	48656916	3	+	26627737	GBM cells	viability after 21 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.04752737830717857	[350]	[206,187]	0	hSpCas9	negative selection	1069080
48661925	48661948	3	+	26627737	GBM cells	viability after 21 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.4228639008761147	[369]	[162,137]	-4	hSpCas9	negative selection	1069081
48655114	48655137	3	-	26627737	RPE1	viability after 9 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.030584847580516106	[1030]	[299,367]	0	hSpCas9	negative selection	1151391
48655376	48655399	3	+	26627737	RPE1	viability after 9 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	7.34308283870737	[1]	[88,117]	9	hSpCas9	negative selection	1151392
48655833	48655856	3	+	26627737	RPE1	viability after 9 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.9818981233028476	[2182]	[1196,1546]	6	hSpCas9	negative selection	1151393
48656183	48656206	3	+	26627737	RPE1	viability after 9 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	0.3137852510302333	[462]	[139,231]	2	hSpCas9	negative selection	1151394
48656893	48656916	3	+	26627737	RPE1	viability after 9 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	1.4431404585777605	[821]	[604,821]	7	hSpCas9	negative selection	1151395
48661925	48661948	3	+	26627737	RPE1	viability after 9 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	0.9198309302182697	[491]	[214,389]	6	hSpCas9	negative selection	1151396
48655114	48655137	3	-	26627737	RPE1	viability after 12 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.530043400942387	[1030]	[185,197]	-4	hSpCas9	negative selection	1233706
48655376	48655399	3	+	26627737	RPE1	viability after 12 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	7.391623850588409	[1]	[131,45]	9	hSpCas9	negative selection	1233707
48655833	48655856	3	+	26627737	RPE1	viability after 12 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	1.2888954192577984	[2182]	[1383,1484]	7	hSpCas9	negative selection	1233708
48656183	48656206	3	+	26627737	RPE1	viability after 12 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.06775448768741754	[462]	[73,165]	0	hSpCas9	negative selection	1233709
48656893	48656916	3	+	26627737	RPE1	viability after 12 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	1.4009637374310295	[821]	[623,539]	7	hSpCas9	negative selection	1233710
48661925	48661948	3	+	26627737	RPE1	viability after 12 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	0.9087901268428242	[491]	[168,331]	5	hSpCas9	negative selection	1233711
48655114	48655137	3	-	26627737	RPE1	viability after 15 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.4669032105132735	[1030]	[125,292]	-3	hSpCas9	negative selection	1316021
48655376	48655399	3	+	26627737	RPE1	viability after 15 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	7.267503436119695	[1]	[161,14]	9	hSpCas9	negative selection	1316022
48655833	48655856	3	+	26627737	RPE1	viability after 15 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	1.172166785359566	[2182]	[1442,1341]	6	hSpCas9	negative selection	1316023
48656183	48656206	3	+	26627737	RPE1	viability after 15 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.4411360858414508	[462]	[41,148]	-3	hSpCas9	negative selection	1316024
48656893	48656916	3	+	26627737	RPE1	viability after 15 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	1.6276940327064915	[821]	[743,693]	8	hSpCas9	negative selection	1316025
48661925	48661948	3	+	26627737	RPE1	viability after 15 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	0.6922029536421329	[491]	[231,217]	4	hSpCas9	negative selection	1316026
48655114	48655137	3	-	26627737	RPE1	viability after 18 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.20474820681299402	[1030]	[311,165]	-1	hSpCas9	negative selection	1398336
48655376	48655399	3	+	26627737	RPE1	viability after 18 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	6.860312590564832	[1]	[97,24]	9	hSpCas9	negative selection	1398337
48655833	48655856	3	+	26627737	RPE1	viability after 18 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	1.209840673693876	[2182]	[1164,1573]	7	hSpCas9	negative selection	1398338
48656183	48656206	3	+	26627737	RPE1	viability after 18 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	0.7253109771772578	[462]	[164,250]	4	hSpCas9	negative selection	1398339
48656893	48656916	3	+	26627737	RPE1	viability after 18 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	1.3755061768316204	[821]	[591,557]	7	hSpCas9	negative selection	1398340
48661925	48661948	3	+	26627737	RPE1	viability after 18 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	1.0545133986454442	[491]	[210,344]	6	hSpCas9	negative selection	1398341
48655114	48655137	3	-	26627737	HeLa	viability after 8 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.5188281978005327	[328]	[291,159,183]	4	hSpCas9	negative selection	1480651
48655376	48655399	3	+	26627737	HeLa	viability after 8 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	1.4794858445186856	[72]	[165,1,112]	9	hSpCas9	negative selection	1480652
48655833	48655856	3	+	26627737	HeLa	viability after 8 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.22816825682699826	[1416]	[759,662,749]	2	hSpCas9	negative selection	1480653
48656183	48656206	3	+	26627737	HeLa	viability after 8 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.44548946800189043	[313]	[100,67,129]	-4	hSpCas9	negative selection	1480654
48656893	48656916	3	+	26627737	HeLa	viability after 8 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.34617556142511274	[780]	[424,489,382]	3	hSpCas9	negative selection	1480655
48661925	48661948	3	+	26627737	HeLa	viability after 8 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.891625326810128	[1032]	[450,230,100]	-7	hSpCas9	negative selection	1480656
48655114	48655137	3	-	26627737	HeLa	viability after 12 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.49095733627448124	[328]	[265,128,186]	4	hSpCas9	negative selection	1562966
48655376	48655399	3	+	26627737	HeLa	viability after 12 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	1.4088524117314687	[72]	[131,68,41]	8	hSpCas9	negative selection	1562967
48655833	48655856	3	+	26627737	HeLa	viability after 12 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.4696852002417351	[1416]	[1064,642,749]	4	hSpCas9	negative selection	1562968
48656183	48656206	3	+	26627737	HeLa	viability after 12 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	0.14524022972144957	[313]	[117,65,253]	1	hSpCas9	negative selection	1562969
48656893	48656916	3	+	26627737	HeLa	viability after 12 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	-0.41909866479612257	[780]	[296,144,293]	-4	hSpCas9	negative selection	1562970
48661925	48661948	3	+	26627737	HeLa	viability after 12 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-1.2171293092181552	[1032]	[227,222,96]	-8	hSpCas9	negative selection	1562971
48655114	48655137	3	-	26627737	HeLa	viability after 15 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.8167341670225475	[328]	[154,399,146]	6	hSpCas9	negative selection	1645281
48655376	48655399	3	+	26627737	HeLa	viability after 15 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	1.4817637098040095	[72]	[167,31,44]	8	hSpCas9	negative selection	1645282
48655833	48655856	3	+	26627737	HeLa	viability after 15 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.14121515081920077	[1416]	[739,424,750]	1	hSpCas9	negative selection	1645283
48656183	48656206	3	+	26627737	HeLa	viability after 15 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-1.5418292390076227	[313]	[21,65,43]	-8	hSpCas9	negative selection	1645284
48656893	48656916	3	+	26627737	HeLa	viability after 15 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	-0.24808889277433155	[780]	[334,214,250]	-2	hSpCas9	negative selection	1645285
48661925	48661948	3	+	26627737	HeLa	viability after 15 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-1.028672041639919	[1032]	[187,219,210]	-7	hSpCas9	negative selection	1645286
48655114	48655137	3	-	26627737	HeLa	viability after 18 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.8699157673436225	[328]	[106,348,146]	6	hSpCas9	negative selection	1727596
48655376	48655399	3	+	26627737	HeLa	viability after 18 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	1.33792781302922	[72]	[100,21,44]	8	hSpCas9	negative selection	1727597
48655833	48655856	3	+	26627737	HeLa	viability after 18 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.14883725861555175	[1416]	[494,361,750]	1	hSpCas9	negative selection	1727598
48656183	48656206	3	+	26627737	HeLa	viability after 18 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-1.4642334076228811	[313]	[15,58,43]	-8	hSpCas9	negative selection	1727599
48656893	48656916	3	+	26627737	HeLa	viability after 18 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	-0.20656661595542136	[780]	[239,177,250]	-2	hSpCas9	negative selection	1727600
48661925	48661948	3	+	26627737	HeLa	viability after 18 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-1.014615984906567	[1032]	[130,180,210]	-7	hSpCas9	negative selection	1727601
48655114	48655137	3	-	26627737	HCT116	viability after 6 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.15593911982907616	[447]	[117,32]	-1	hSpCas9	negative selection	1809911
48655376	48655399	3	+	26627737	HCT116	viability after 6 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	0.6549145605536766	[56]	[26,6]	3	hSpCas9	negative selection	1809912
48655833	48655856	3	+	26627737	HCT116	viability after 6 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	1.736647836897474	[1429]	[812,713]	8	hSpCas9	negative selection	1809913
48656183	48656206	3	+	26627737	HCT116	viability after 6 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-1.6146129139420466	[618]	[34,29]	-7	hSpCas9	negative selection	1809914
48656893	48656916	3	+	26627737	HCT116	viability after 6 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	-0.3794959046162355	[1030]	[170,98]	-2	hSpCas9	negative selection	1809915
48661925	48661948	3	+	26627737	HCT116	viability after 6 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.26583765318141184	[1229]	[281,93]	-1	hSpCas9	negative selection	1809916
48655114	48655137	3	-	26627737	HCT116	viability after 8 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.5927893351285348	[374]	[175,120,114]	-6	hSpCas9	negative selection	1892226
48655376	48655399	3	+	26627737	HCT116	viability after 8 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-1.3060529552503002	[93]	[26,18,16]	-9	hSpCas9	negative selection	1892227
48655833	48655856	3	+	26627737	HCT116	viability after 8 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	-0.15026112168580874	[938]	[405,555,435]	-2	hSpCas9	negative selection	1892228
48656183	48656206	3	+	26627737	HCT116	viability after 8 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	1.193045811542048	[54]	[69,77,59]	8	hSpCas9	negative selection	1892229
48656893	48656916	3	+	26627737	HCT116	viability after 8 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.40222787694120576	[396]	[321,183,360]	4	hSpCas9	negative selection	1892230
48661925	48661948	3	+	26627737	HCT116	viability after 8 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.810804672543729	[651]	[142,156,311]	-7	hSpCas9	negative selection	1892231
48655114	48655137	3	-	26627737	HCT116	viability after 9 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	1.2068184764112646	[447]	[107,408]	7	hSpCas9	negative selection	1974541
48655376	48655399	3	+	26627737	HCT116	viability after 9 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	2.3057626535435087	[56]	[48,95]	9	hSpCas9	negative selection	1974542
48655833	48655856	3	+	26627737	HCT116	viability after 9 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	1.250339936254131	[1429]	[775,1012]	8	hSpCas9	negative selection	1974543
48656183	48656206	3	+	26627737	HCT116	viability after 9 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	0.41355790939945547	[618]	[356,111]	3	hSpCas9	negative selection	1974544
48656893	48656916	3	+	26627737	HCT116	viability after 9 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	-1.596901345933543	[1030]	[47,124]	-8	hSpCas9	negative selection	1974545
48661925	48661948	3	+	26627737	HCT116	viability after 9 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-2.3445024474071623	[1229]	[105,31]	-9	hSpCas9	negative selection	1974546
48655114	48655137	3	-	26627737	HCT116	viability after 12 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.22543356809010426	[374]	[118,207,183]	-2	hSpCas9	negative selection	2056856
48655376	48655399	3	+	26627737	HCT116	viability after 12 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-0.6222193443832074	[93]	[74,10,5]	-6	hSpCas9	negative selection	2056857
48655833	48655856	3	+	26627737	HCT116	viability after 12 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.4699896689132983	[938]	[866,625,539]	4	hSpCas9	negative selection	2056858
48656183	48656206	3	+	26627737	HCT116	viability after 12 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	1.5124541346698597	[54]	[39,118,92]	9	hSpCas9	negative selection	2056859
48656893	48656916	3	+	26627737	HCT116	viability after 12 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.3039987860087964	[396]	[276,215,276]	3	hSpCas9	negative selection	2056860
48661925	48661948	3	+	26627737	HCT116	viability after 12 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-1.0660096578642686	[651]	[108,213,173]	-8	hSpCas9	negative selection	2056861
48655114	48655137	3	-	26627737	HCT116	viability after 15 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-1.1031978706380934	[374]	[75,138,82]	-8	hSpCas9	negative selection	2139171
48655376	48655399	3	+	26627737	HCT116	viability after 15 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-0.7519331616716276	[93]	[43,52,0]	-6	hSpCas9	negative selection	2139172
48655833	48655856	3	+	26627737	HCT116	viability after 15 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.1170575420251192	[938]	[558,824,369]	1	hSpCas9	negative selection	2139173
48656183	48656206	3	+	26627737	HCT116	viability after 15 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	1.9918937591584436	[54]	[75,262,32]	9	hSpCas9	negative selection	2139174
48656893	48656916	3	+	26627737	HCT116	viability after 15 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.6843503643240698	[396]	[449,265,392]	6	hSpCas9	negative selection	2139175
48661925	48661948	3	+	26627737	HCT116	viability after 15 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.27101000810545606	[651]	[273,547,106]	-3	hSpCas9	negative selection	2139176
48655114	48655137	3	-	26627737	HCT116	viability after 18 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	-0.09533321554080795	[374]	[262,157,84]	-1	hSpCas9	negative selection	2221486
48655376	48655399	3	+	26627737	HCT116	viability after 18 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-0.5325734876432666	[93]	[84,2,6]	-5	hSpCas9	negative selection	2221487
48655833	48655856	3	+	26627737	HCT116	viability after 18 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.8008568117808437	[938]	[586,1204,541]	6	hSpCas9	negative selection	2221488
48656183	48656206	3	+	26627737	HCT116	viability after 18 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	2.411933127504556	[54]	[93,233,87]	9	hSpCas9	negative selection	2221489
48656893	48656916	3	+	26627737	HCT116	viability after 18 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	1.09704615882802	[396]	[463,291,486]	8	hSpCas9	negative selection	2221490
48661925	48661948	3	+	26627737	HCT116	viability after 18 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.6332358382181871	[651]	[135,287,178]	-5	hSpCas9	negative selection	2221491
48657963	48657986	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTATGTCAGGG	CELSR3	ENSG00000008300	0.44891892466681377	[169,63]	[43,23]	2	dCas9-VP64	positive selection	2417535
48657963	48657986	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTATGTCAGGG	CELSR3	ENSG00000008300	-1.5346517863780793	[45,444]	[19,33]	-9	dCas9-VP64	positive selection	2512790
48661830	48661853	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGCTGTCCGAGACTCGCGGGG	CELSR3	ENSG00000008300	0.446829224024907	[0,0]	[1,0]	8	hSpCas9	positive selection	2978491
48662418	48662441	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTCTTCCGGGGTCCGGGAGG	CELSR3	ENSG00000008300	0.6521005688954193	[3,3]	[2,6]	9	hSpCas9	positive selection	2978492
48662012	48662035	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAATTCCCCACAGCAGCGCGCGG	CELSR3	ENSG00000008300	-0.3168921462134187	[2,3]	[3,0]	-4	hSpCas9	positive selection	2978493
48659143	48659166	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCATTCTGGTCAACCAGGCGG	CELSR3	ENSG00000008300	0.32370543294496157	[4,4]	[4,6]	6	hSpCas9	positive selection	2978494
48661830	48661853	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGCTGTCCGAGACTCGCGGGG	CELSR3	ENSG00000008300	0.4833744715089985	[0,0]	[0,0]	8	hSpCas9	positive selection	3046349
48662418	48662441	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTCTTCCGGGGTCCGGGAGG	CELSR3	ENSG00000008300	0.24202435854448864	[3,3]	[3,2]	4	hSpCas9	positive selection	3046350
48662012	48662035	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAATTCCCCACAGCAGCGCGCGG	CELSR3	ENSG00000008300	0.36357207974026096	[2,2]	[2,1]	6	hSpCas9	positive selection	3046351
48659143	48659166	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCATTCTGGTCAACCAGGCGG	CELSR3	ENSG00000008300	0.3234297767409951	[4,4]	[5,3]	5	hSpCas9	positive selection	3046352
48661542	48661565		-	24336571	A375	resistance to PLX after 7 days	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.38250310935660625	[4,4]	[3,2]	-9	hSpCas9	positive selection	3104912
48661461	48661484		-	24336571	A375	resistance to PLX after 7 days	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.5708148889433287	[8,7]	[4,5]	-9	hSpCas9	positive selection	3104913
48656753	48656776		+	24336571	A375	resistance to PLX after 7 days	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.051713604166661986	[18,13]	[14,15]	-1	hSpCas9	positive selection	3104914
48661542	48661565		-	24336571	A375	resistance to PLX after 14 days	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.5126196850647836	[4,3]	[1,2]	5	hSpCas9	positive selection	3162705
48661461	48661484		-	24336571	A375	resistance to PLX after 14 days	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.6233307459532396	[9,7]	[1,1]	-7	hSpCas9	positive selection	3162706
48656753	48656776		+	24336571	A375	resistance to PLX after 14 days	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.6947454719014692	[13,13]	[3,3]	-7	hSpCas9	positive selection	3162707
48661542	48661565		-	24336571	A375	viability after 7 days	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.13383181901026875	[5]	[4,4]	-2	hSpCas9	negative selection	3220498
48661461	48661484		-	24336571	A375	viability after 7 days	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.4021464782420783	[6]	[8,7]	6	hSpCas9	negative selection	3220499
48656753	48656776		+	24336571	A375	viability after 7 days	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	0.07612859252243992	[15]	[18,13]	1	hSpCas9	negative selection	3220500
48661542	48661565		-	24336571	A375	viability after 14 days	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.258263824746618	[5]	[4,3]	-3	hSpCas9	negative selection	3278291
48661461	48661484		-	24336571	A375	viability after 14 days	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.5293641833511062	[6]	[9,7]	6	hSpCas9	negative selection	3278292
48656753	48656776		+	24336571	A375	viability after 14 days	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.12456143158712116	[15]	[13,13]	-1	hSpCas9	negative selection	3278293
48661542	48661565	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	1.1478454679713939	[75,61]	[0,0]	5	hSpCas9	positive selection	3342637
48661461	48661484	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.9469955962877328	[57,100]	[0,0]	4	hSpCas9	positive selection	3342638
48656753	48656776	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.06466081585880194	[160,158]	[0,0]	0	hSpCas9	positive selection	3342639
48656176	48656199	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	6.794699253648731	[112,112]	[81,81]	9	hSpCas9	positive selection	3361872
48656178	48656201	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3361873
48657322	48657345	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3361874
48661829	48661852	3	+	26780180	HT29	viability (Avana library 4 designs)	GGAGCTGTCCGAGACTCGCGGGG	CELSR3	ENSG00000008300	1.20915611525768	[]	[]	5	hSpCas9	negative selection	3414823
48662418	48662441	3	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTCTTCCGGGGTCCGGGAGG	CELSR3	ENSG00000008300	1.78624711408983	[]	[]	6	hSpCas9	negative selection	3414824
48662011	48662034	3	+	26780180	HT29	viability (Avana library 4 designs)	TAATTCCCCACAGCAGCGCGCGG	CELSR3	ENSG00000008300	0.837415690230439	[]	[]	3	hSpCas9	negative selection	3414825
48659142	48659165	3	+	26780180	HT29	viability (Avana library 4 designs)	TGTCATTCTGGTCAACCAGGCGG	CELSR3	ENSG00000008300	-0.0513932755089038	[]	[]	-1	hSpCas9	negative selection	3414826
48659142	48659165	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCATTCTGGTCAACCAGGCGG	CELSR3	ENSG00000008300	-2.03622270184478	[]	[]	-2	hSpCas9	negative selection	3491529
48661829	48661852	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGCTGTCCGAGACTCGCGGGG	CELSR3	ENSG00000008300	-4.28527057895696	[]	[]	-5	hSpCas9	negative selection	3491530
48662418	48662441	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTCTTCCGGGGTCCGGGAGG	CELSR3	ENSG00000008300	4.6099664000153	[]	[]	7	hSpCas9	negative selection	3491531
48662011	48662034	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAATTCCCCACAGCAGCGCGCGG	CELSR3	ENSG00000008300	3.94287649823559	[]	[]	6	hSpCas9	negative selection	3491532
48661881	48661904	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGATTCAGCACCACGCACGG	CELSR3	ENSG00000008300	1.57093508066427	[]	[]	2	hSpCas9	negative selection	3491533
48655072	48655095	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTGGCAACTACTCATGCGCGG	CELSR3	ENSG00000008300	4.70760540425628	[]	[]	7	hSpCas9	negative selection	3491534
48659142	48659165	3	+	26780180	A375	viability (Avana lentiGuide)	TGTCATTCTGGTCAACCAGGCGG	CELSR3	ENSG00000008300	-0.890291292876263	[]	[]	-1	hSpCas9	negative selection	3600188
48661829	48661852	3	+	26780180	A375	viability (Avana lentiGuide)	GGAGCTGTCCGAGACTCGCGGGG	CELSR3	ENSG00000008300	13.6125076935052	[]	[]	7	hSpCas9	negative selection	3600189
48662418	48662441	3	-	26780180	A375	viability (Avana lentiGuide)	GGAGTCTTCCGGGGTCCGGGAGG	CELSR3	ENSG00000008300	4.39708495498429	[]	[]	4	hSpCas9	negative selection	3600190
48662011	48662034	3	+	26780180	A375	viability (Avana lentiGuide)	TAATTCCCCACAGCAGCGCGCGG	CELSR3	ENSG00000008300	-2.19468523654948	[]	[]	-4	hSpCas9	negative selection	3600191
48661881	48661904	3	-	26780180	A375	viability (Avana lentiGuide)	GCTGGATTCAGCACCACGCACGG	CELSR3	ENSG00000008300	-1.29582762696593	[]	[]	-2	hSpCas9	negative selection	3600192
48655072	48655095	3	-	26780180	A375	viability (Avana lentiGuide)	GATTGGCAACTACTCATGCGCGG	CELSR3	ENSG00000008300	-1.48318202072975	[]	[]	-2	hSpCas9	negative selection	3600193
48659142	48659165	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCATTCTGGTCAACCAGGCGG	CELSR3	ENSG00000008300	-0.19989629420302857	[6]	[6,4]	-3	hSpCas9	positive selection	3708847
48661829	48661852	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGCTGTCCGAGACTCGCGGGG	CELSR3	ENSG00000008300	-0.6783483595714336	[2]	[0,0]	-7	hSpCas9	positive selection	3708848
48662418	48662441	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTCTTCCGGGGTCCGGGAGG	CELSR3	ENSG00000008300	0.06104381875703434	[4]	[4,4]	1	hSpCas9	positive selection	3708849
48662011	48662034	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAATTCCCCACAGCAGCGCGCGG	CELSR3	ENSG00000008300	0.07664839805091907	[5]	[4,5]	2	hSpCas9	positive selection	3708850
48661881	48661904	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGATTCAGCACCACGCACGG	CELSR3	ENSG00000008300	0.2123091202199764	[5]	[6,6]	6	hSpCas9	positive selection	3708851
48655072	48655095	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTGGCAACTACTCATGCGCGG	CELSR3	ENSG00000008300	0.24303457850163795	[4]	[5,5]	7	hSpCas9	positive selection	3708852
48659142	48659165	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCATTCTGGTCAACCAGGCGG	CELSR3	ENSG00000008300	0.2134968190778957	[6]	[6,6]	5	hSpCas9	positive selection	3817454
48661829	48661852	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGCTGTCCGAGACTCGCGGGG	CELSR3	ENSG00000008300	-1.5252007899602749	[2]	[0,0]	-9	hSpCas9	positive selection	3817455
48662418	48662441	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTCTTCCGGGGTCCGGGAGG	CELSR3	ENSG00000008300	-0.16686795565366597	[5]	[3,3]	-2	hSpCas9	positive selection	3817456
48662011	48662034	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAATTCCCCACAGCAGCGCGCGG	CELSR3	ENSG00000008300	0.20462249309344369	[4]	[4,4]	5	hSpCas9	positive selection	3817457
48661881	48661904	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGATTCAGCACCACGCACGG	CELSR3	ENSG00000008300	0.04791454764081686	[6]	[5,4]	1	hSpCas9	positive selection	3817458
48655072	48655095	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTGGCAACTACTCATGCGCGG	CELSR3	ENSG00000008300	-0.3465444043127186	[5]	[2,4]	-4	hSpCas9	positive selection	3817459
48657322	48657345	3	+	26780180	A375	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.947766007045985	[]	[]	4	hSpCas9	negative selection	3925617
48656176	48656199	3	-	26780180	A375	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.78961536159866	[]	[]	3	hSpCas9	negative selection	3925618
48661542	48661565	3	-	26780180	A375	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	2.17006171904961	[]	[]	9	hSpCas9	negative selection	3925619
48656178	48656201	3	+	26780180	A375	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	1.60741700045473	[]	[]	8	hSpCas9	negative selection	3925620
48661461	48661484	3	-	26780180	A375	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	1.84251546075413	[]	[]	9	hSpCas9	negative selection	3925621
48656753	48656776	3	+	26780180	A375	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	1.24367030228503	[]	[]	6	hSpCas9	negative selection	3925622
48657322	48657345	3	+	26780180	HT29	viability (GeCKOv2 library)	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.951396820509591	[]	[]	4	hSpCas9	negative selection	4033583
48656176	48656199	3	-	26780180	HT29	viability (GeCKOv2 library)	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.754521753534264	[]	[]	3	hSpCas9	negative selection	4033584
48661542	48661565	3	-	26780180	HT29	viability (GeCKOv2 library)	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	2.98135655121907	[]	[]	9	hSpCas9	negative selection	4033585
48656178	48656201	3	+	26780180	HT29	viability (GeCKOv2 library)	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	1.50989338137034	[]	[]	7	hSpCas9	negative selection	4033586
48661461	48661484	3	-	26780180	HT29	viability (GeCKOv2 library)	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	2.09015569581142	[]	[]	9	hSpCas9	negative selection	4033587
48656753	48656776	3	+	26780180	HT29	viability (GeCKOv2 library)	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	1.5400249980333	[]	[]	7	hSpCas9	negative selection	4033588
48661542	48661565	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.040911288977896976	[2]	[1,1]	-1	hSpCas9	positive selection	4126962
48661461	48661484	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.5448507619084264	[3]	[1,0]	-9	hSpCas9	positive selection	4126963
48656753	48656776	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.21080415342156172	[3]	[2,1]	-5	hSpCas9	positive selection	4126964
48661542	48661565	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.04136803763586572	[1]	[0,1,0,0]	0	hSpCas9	positive selection	4190984
48661461	48661484	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.054998282110445884	[1]	[1,0,0,0]	-1	hSpCas9	positive selection	4190985
48656753	48656776	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.4104888859055863	[4]	[2,0,1,0]	-6	hSpCas9	positive selection	4190986
48661542	48661565	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.8191977581586681	[2]	[1,0]	-9	hSpCas9	positive selection	4262725
48661461	48661484	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.020551095157880193	[3]	[2,1]	0	hSpCas9	positive selection	4262726
48656753	48656776	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.14565330819521852	[3]	[3,2]	-3	hSpCas9	positive selection	4262727
48656176	48656199	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.45640172998448364	[2]	[3,2]	8	hSpCas9	positive selection	4327000
48656178	48656201	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	0.7305277903161067	[2]	[2,4]	9	hSpCas9	positive selection	4327001
48657322	48657345	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.40901272271671635	[2]	[2,0]	-7	hSpCas9	positive selection	4327002
48659053	48659075	3	+	27760321	OCIAML3	viability	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	-0.013792190752569267	[653,510]	[277,669]	0	hSpCas9	negative selection	4388455
48660930	48660952	3	-	27760321	OCIAML3	viability	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	0.2611387187933031	[780,654]	[599,761]	3	hSpCas9	negative selection	4388456
48661465	48661487	3	+	27760321	OCIAML3	viability	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.04644651929025345	[689,673]	[564,455]	0	hSpCas9	negative selection	4388457
48662265	48662287	3	+	27760321	OCIAML3	viability	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.5875901922088491	[483,493]	[514,657]	7	hSpCas9	negative selection	4388458
48662460	48662482	3	+	27760321	OCIAML3	viability	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.11345987931435508	[732,691]	[516,715]	1	hSpCas9	negative selection	4388459
48659053	48659075	3	+	27760321	OCIAML2	viability	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.07946573290139658	[653,510]	[459,539]	1	hSpCas9	negative selection	4471918
48660930	48660952	3	-	27760321	OCIAML2	viability	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	-0.03691820700162185	[780,654]	[509,634]	0	hSpCas9	negative selection	4471919
48661465	48661487	3	+	27760321	OCIAML2	viability	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.4633312654365435	[689,673]	[366,445]	-5	hSpCas9	negative selection	4471920
48662265	48662287	3	+	27760321	OCIAML2	viability	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.3578081263054431	[483,493]	[401,649]	5	hSpCas9	negative selection	4471921
48662460	48662482	3	+	27760321	OCIAML2	viability	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.023362640695883008	[732,691]	[474,732]	0	hSpCas9	negative selection	4471922
48659053	48659075	3	+	27760321	MV411	viability	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	-0.3338166027530646	[653,510]	[204,449]	-2	hSpCas9	negative selection	4555381
48660930	48660952	3	-	27760321	MV411	viability	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	0.31376968351011203	[780,654]	[602,561]	2	hSpCas9	negative selection	4555382
48661465	48661487	3	+	27760321	MV411	viability	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	0.5914351754992203	[689,673]	[785,519]	4	hSpCas9	negative selection	4555383
48662265	48662287	3	+	27760321	MV411	viability	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.4185287752431859	[483,493]	[283,656]	3	hSpCas9	negative selection	4555384
48662460	48662482	3	+	27760321	MV411	viability	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.4236862822285218	[732,691]	[458,889]	3	hSpCas9	negative selection	4555385
48659053	48659075	3	+	27760321	HL60	viability	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	-0.4620043041846239	[653,510]	[395,286]	-5	hSpCas9	negative selection	4638844
48660930	48660952	3	-	27760321	HL60	viability	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	-0.546843032981017	[780,654]	[429,367]	-5	hSpCas9	negative selection	4638845
48661465	48661487	3	+	27760321	HL60	viability	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	0.19392200566331586	[689,673]	[480,805]	2	hSpCas9	negative selection	4638846
48662265	48662287	3	+	27760321	HL60	viability	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.7380707187881969	[483,493]	[569,773]	8	hSpCas9	negative selection	4638847
48662460	48662482	3	+	27760321	HL60	viability	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	-0.17833140943474757	[732,691]	[508,520]	-2	hSpCas9	negative selection	4638848
48659053	48659075	3	+	27760321	HT1080	viability	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	1.0580598782302821	[510,398]	[480,263]	6	hSpCas9	negative selection	4722307
48660930	48660952	3	-	27760321	HT1080	viability	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	0.32936074565401596	[654,510]	[371,203]	1	hSpCas9	negative selection	4722308
48661465	48661487	3	+	27760321	HT1080	viability	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.09460650105991586	[673,525]	[304,134]	0	hSpCas9	negative selection	4722309
48662265	48662287	3	+	27760321	HT1080	viability	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.8610999858261201	[493,385]	[305,331]	4	hSpCas9	negative selection	4722310
48662460	48662482	3	+	27760321	HT1080	viability	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	-0.06408720886467467	[691,539]	[207,263]	0	hSpCas9	negative selection	4722311
48659053	48659075	3	+	27760321	HT29	viability after 7 days	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.5505158935656136	[510,398]	[787,869,899]	8	hSpCas9	negative selection	4805770
48660930	48660952	3	-	27760321	HT29	viability after 7 days	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	-0.33675527526104126	[654,510]	[704,637,456]	-5	hSpCas9	negative selection	4805771
48661465	48661487	3	+	27760321	HT29	viability after 7 days	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.04284385848465355	[673,525]	[886,623,753]	0	hSpCas9	negative selection	4805772
48662265	48662287	3	+	27760321	HT29	viability after 7 days	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	-0.2254896226859562	[493,385]	[531,478,447]	-3	hSpCas9	negative selection	4805773
48662460	48662482	3	+	27760321	HT29	viability after 7 days	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	-0.02865045611927408	[691,539]	[787,676,861]	0	hSpCas9	negative selection	4805774
48659053	48659075	3	+	27760321	HT29	viability after 25 days	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.7584921517958376	[510,398]	[1135,636,844]	8	hSpCas9	negative selection	4889233
48660930	48660952	3	-	27760321	HT29	viability after 25 days	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	-0.3268637185508487	[654,510]	[642,382,562]	-3	hSpCas9	negative selection	4889234
48661465	48661487	3	+	27760321	HT29	viability after 25 days	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.1562553385591695	[673,525]	[601,514,741]	-2	hSpCas9	negative selection	4889235
48662265	48662287	3	+	27760321	HT29	viability after 25 days	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.4993773121660031	[493,385]	[722,513,914]	5	hSpCas9	negative selection	4889236
48662460	48662482	3	+	27760321	HT29	viability after 25 days	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.20287566624318942	[691,539]	[546,1072,827]	2	hSpCas9	negative selection	4889237
48659053	48659075	3	+	27760321	HT29	viability after 22 days	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.6787095039237092	[510,398]	[993,879,645]	7	hSpCas9	negative selection	4972696
48660930	48660952	3	-	27760321	HT29	viability after 22 days	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	0.07440278184451776	[654,510]	[685,576,867]	0	hSpCas9	negative selection	4972697
48661465	48661487	3	+	27760321	HT29	viability after 22 days	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.01496684825443606	[673,525]	[492,634,938]	0	hSpCas9	negative selection	4972698
48662265	48662287	3	+	27760321	HT29	viability after 22 days	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.08888821844073475	[493,385]	[677,541,397]	0	hSpCas9	negative selection	4972699
48662460	48662482	3	+	27760321	HT29	viability after 22 days	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.29345607055166567	[691,539]	[975,916,720]	3	hSpCas9	negative selection	4972700
48659053	48659075	3	+	27760321	HT29	viability after 19 days	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.5303124435397037	[510,398]	[1205,725,383]	5	hSpCas9	negative selection	5056159
48660930	48660952	3	-	27760321	HT29	viability after 19 days	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	-0.43735879884333007	[654,510]	[458,566,448]	-4	hSpCas9	negative selection	5056160
48661465	48661487	3	+	27760321	HT29	viability after 19 days	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	0.2727642484899728	[673,525]	[911,963,626]	2	hSpCas9	negative selection	5056161
48662265	48662287	3	+	27760321	HT29	viability after 19 days	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	-0.019904648254660207	[493,385]	[640,342,518]	0	hSpCas9	negative selection	5056162
48662460	48662482	3	+	27760321	HT29	viability after 19 days	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.0006983679272760668	[691,539]	[795,767,564]	0	hSpCas9	negative selection	5056163
48659053	48659075	3	+	27760321	HT29	viability after 16 days	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.3850337980805461	[510,398]	[511,1002,455]	4	hSpCas9	negative selection	5139622
48660930	48660952	3	-	27760321	HT29	viability after 16 days	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	-0.6295538863421343	[654,510]	[423,457,381]	-5	hSpCas9	negative selection	5139623
48661465	48661487	3	+	27760321	HT29	viability after 16 days	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	0.052161322723147885	[673,525]	[764,710,617]	0	hSpCas9	negative selection	5139624
48662265	48662287	3	+	27760321	HT29	viability after 16 days	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.3246183990710676	[493,385]	[765,563,534]	3	hSpCas9	negative selection	5139625
48662460	48662482	3	+	27760321	HT29	viability after 16 days	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.26032320525557295	[691,539]	[896,863,720]	3	hSpCas9	negative selection	5139626
48659053	48659075	3	+	27760321	HT29	viability after 13 days	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.3181406389856734	[510,398]	[491,865,618]	4	hSpCas9	negative selection	5223085
48660930	48660952	3	-	27760321	HT29	viability after 13 days	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	-0.099139293326442	[654,510]	[598,830,473]	-1	hSpCas9	negative selection	5223086
48661465	48661487	3	+	27760321	HT29	viability after 13 days	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.10219448459823222	[673,525]	[868,550,531]	-1	hSpCas9	negative selection	5223087
48662265	48662287	3	+	27760321	HT29	viability after 13 days	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	-0.026261309284751677	[493,385]	[394,590,516]	0	hSpCas9	negative selection	5223088
48662460	48662482	3	+	27760321	HT29	viability after 13 days	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.4131380743491623	[691,539]	[1053,945,859]	5	hSpCas9	negative selection	5223089
48659053	48659075	3	+	27760321	HT29	viability after 10 days	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	0.7607853473185344	[510,398]	[803,979,1100]	9	hSpCas9	negative selection	5306548
48660930	48660952	3	-	27760321	HT29	viability after 10 days	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	0.09313393464194919	[654,510]	[721,977,637]	1	hSpCas9	negative selection	5306549
48661465	48661487	3	+	27760321	HT29	viability after 10 days	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	-0.0945396369397069	[673,525]	[518,868,720]	-1	hSpCas9	negative selection	5306550
48662265	48662287	3	+	27760321	HT29	viability after 10 days	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	0.25075516207830484	[493,385]	[789,572,596]	3	hSpCas9	negative selection	5306551
48662460	48662482	3	+	27760321	HT29	viability after 10 days	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.08856481857047904	[691,539]	[560,1107,792]	1	hSpCas9	negative selection	5306552
48659053	48659075	3	+	27760321	MOLM13	viability	GCGCCCAATAATGCCCGACGGG	CELSR3	ENSG00000008300	1.414677701838031	[653,510]	[1633,219]	8	hSpCas9	negative selection	5390011
48660930	48660952	3	-	27760321	MOLM13	viability	ACAGTCGTGCTGCGCGTCACGG	CELSR3	ENSG00000008300	0.20460308593846233	[780,654]	[444,481]	1	hSpCas9	negative selection	5390012
48661465	48661487	3	+	27760321	MOLM13	viability	AGCTGCCGCCGTACGGATAAGG	CELSR3	ENSG00000008300	0.2035895332876344	[689,673]	[354,519]	1	hSpCas9	negative selection	5390013
48662265	48662287	3	+	27760321	MOLM13	viability	CTCGTTCGCGGCTGCCCAATGG	CELSR3	ENSG00000008300	1.7863779370795445	[483,493]	[1007,910]	9	hSpCas9	negative selection	5390014
48662460	48662482	3	+	27760321	MOLM13	viability	CGCCACCGATATGCGCCCTTGG	CELSR3	ENSG00000008300	0.7913892753164734	[732,691]	[428,923]	5	hSpCas9	negative selection	5390015
48662462	48662485	3	-	27661255	K562	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	-0.06838719258423775	[1298,1086]	[975,856]	-3	dCas9-KRAB	negative selection	5470206
48662839	48662862	3	-	27661255	K562	viability	GCGTCGGGGATGCTGTGGTGGGG	CELSR3	ENSG00000008300	0.18515517453986086	[564,773]	[663,553]	6	dCas9-KRAB	negative selection	5470207
48662877	48662900	3	-	27661255	K562	viability	GGCCGGGAGCCATGTTGGAGCGG	CELSR3	ENSG00000008300	0.03500660211028295	[520,500]	[431,406]	1	dCas9-KRAB	negative selection	5470208
48661542	48661565	3	-	27260156	BXPC3	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.0374630861674134	[452]	[407,432,720,381]	0	hSpCas9	negative selection	5535185
48661461	48661484	3	-	27260156	BXPC3	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.10111067665643025	[559]	[589,582,632,719]	2	hSpCas9	negative selection	5535186
48656753	48656776	3	+	27260156	BXPC3	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.14346192465951102	[929]	[888,845,855,930]	-3	hSpCas9	negative selection	5535187
48656176	48656199	3	-	27260156	BXPC3	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.1596367057459238	[284]	[245,471,296,311]	3	hSpCas9	negative selection	5599460
48656178	48656201	3	+	27260156	BXPC3	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.0567937746890632	[315]	[146,124,193,173]	-9	hSpCas9	negative selection	5599461
48657322	48657345	3	+	27260156	BXPC3	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.07070640546792914	[382]	[370,437,456,417]	1	hSpCas9	negative selection	5599462
48661542	48661565	3	-	27260156	A673	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.26273718876480223	[452]	[599,537,820,644]	6	hSpCas9	negative selection	5656436
48661461	48661484	3	-	27260156	A673	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.4115561308856095	[559]	[560,461,582,416]	-7	hSpCas9	negative selection	5656437
48656753	48656776	3	+	27260156	A673	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.05240955194324237	[929]	[1068,1000,1078,1161]	-1	hSpCas9	negative selection	5656438
48656176	48656199	3	-	27260156	A673	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.0819102239921573	[284]	[346,293,390,418]	2	hSpCas9	negative selection	5720711
48656178	48656201	3	+	27260156	A673	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.8823458174215424	[315]	[178,165,229,247]	-9	hSpCas9	negative selection	5720712
48657322	48657345	3	+	27260156	A673	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.28609689979140984	[382]	[412,374,351,371]	-6	hSpCas9	negative selection	5720713
48661542	48661565	3	-	27260156	A375	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.09752631781859387	[452]	[673,724,346,541]	1	hSpCas9	negative selection	5777687
48661461	48661484	3	-	27260156	A375	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.5678108461847172	[559]	[508,437,500,328]	-6	hSpCas9	negative selection	5777688
48656753	48656776	3	+	27260156	A375	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.29785079902911404	[929]	[973,953,845,779]	-4	hSpCas9	negative selection	5777689
48656176	48656199	3	-	27260156	A375	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.5347882915441046	[284]	[327,606,559,451]	7	hSpCas9	negative selection	5841962
48656178	48656201	3	+	27260156	A375	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.7666706999818951	[315]	[241,257,166,206]	-7	hSpCas9	negative selection	5841963
48657322	48657345	3	+	27260156	A375	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.01941390676889032	[382]	[186,578,508,498]	0	hSpCas9	negative selection	5841964
48661542	48661565	3	-	27260156	COLO741	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.0487435306168362	[452]	[567,594,626]	1	hSpCas9	negative selection	5898938
48661461	48661484	3	-	27260156	COLO741	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.2957989405288577	[559]	[599,694,462]	-6	hSpCas9	negative selection	5898939
48656753	48656776	3	+	27260156	COLO741	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.15016522484295325	[929]	[951,1146,1098]	-3	hSpCas9	negative selection	5898940
48656176	48656199	3	-	27260156	COLO741	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.4353087568478809	[284]	[487,526,462]	8	hSpCas9	negative selection	5963213
48656178	48656201	3	+	27260156	COLO741	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.9557389046868374	[315]	[264,214,152]	-9	hSpCas9	negative selection	5963214
48657322	48657345	3	+	27260156	COLO741	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.012146756614688337	[382]	[431,460,574]	0	hSpCas9	negative selection	5963215
48661542	48661565	3	-	27260156	CAL120	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.07796007221613203	[452]	[802,581,433]	1	hSpCas9	negative selection	6020189
48661461	48661484	3	-	27260156	CAL120	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.7575684043518741	[559]	[401,372,458]	-8	hSpCas9	negative selection	6020190
48656753	48656776	3	+	27260156	CAL120	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.6888382234013045	[929]	[882,727,569]	-7	hSpCas9	negative selection	6020191
48656176	48656199	3	-	27260156	CAL120	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	-0.13180903168415614	[284]	[324,259,384]	-2	hSpCas9	negative selection	6084464
48656178	48656201	3	+	27260156	CAL120	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.551368945578658	[315]	[87,145,160]	-9	hSpCas9	negative selection	6084465
48657322	48657345	3	+	27260156	CAL120	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.3179903322476949	[382]	[344,458,337]	-5	hSpCas9	negative selection	6084466
48661542	48661565	3	-	27260156	CADOES1	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.09133181712660901	[452]	[428,488,416,460]	1	hSpCas9	negative selection	6141440
48661461	48661484	3	-	27260156	CADOES1	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.23528498413702764	[559]	[555,345,458,406]	-4	hSpCas9	negative selection	6141441
48656753	48656776	3	+	27260156	CADOES1	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.26990240203417626	[929]	[776,545,750,797]	-5	hSpCas9	negative selection	6141442
48656176	48656199	3	-	27260156	CADOES1	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.16269864573203396	[284]	[340,216,294,334]	3	hSpCas9	negative selection	6205715
48656178	48656201	3	+	27260156	CADOES1	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.7428958185473187	[315]	[179,161,220,137]	-8	hSpCas9	negative selection	6205716
48657322	48657345	3	+	27260156	CADOES1	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.1676005736029438	[382]	[380,489,319,409]	3	hSpCas9	negative selection	6205717
48661542	48661565	3	-	27260156	EWS502	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.017833633205924244	[452]	[420,669,327,470]	0	hSpCas9	negative selection	6262691
48661461	48661484	3	-	27260156	EWS502	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.21230970775552888	[559]	[478,482,593,494]	-4	hSpCas9	negative selection	6262692
48656753	48656776	3	+	27260156	EWS502	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.44020353938348056	[929]	[588,647,852,840]	-6	hSpCas9	negative selection	6262693
48656176	48656199	3	-	27260156	EWS502	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.05315100179615706	[284]	[254,350,312,339]	0	hSpCas9	negative selection	6326966
48656178	48656201	3	+	27260156	EWS502	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.888624726792796	[315]	[196,146,133,247]	-8	hSpCas9	negative selection	6326967
48657322	48657345	3	+	27260156	EWS502	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.07366980797624761	[382]	[325,541,331,336]	-1	hSpCas9	negative selection	6326968
48661542	48661565	3	-	27260156	EW8	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.15525613263341387	[452]	[475,514,273,399]	3	hSpCas9	negative selection	6383942
48661461	48661484	3	-	27260156	EW8	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.577326912108472	[559]	[432,261,231,314]	-8	hSpCas9	negative selection	6383943
48656753	48656776	3	+	27260156	EW8	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.3875294106403008	[929]	[707,535,452,640]	-6	hSpCas9	negative selection	6383944
48656176	48656199	3	-	27260156	EW8	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.07868907083831089	[284]	[274,293,188,229]	1	hSpCas9	negative selection	6448217
48656178	48656201	3	+	27260156	EW8	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.1458839602532735	[315]	[104,180,90,88]	-9	hSpCas9	negative selection	6448218
48657322	48657345	3	+	27260156	EW8	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.0130228390192349	[382]	[244,324,304,347]	0	hSpCas9	negative selection	6448219
48661542	48661565	3	-	27260156	CORL105	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.040804489936282905	[452]	[700,386,636,479]	0	hSpCas9	negative selection	6505193
48661461	48661484	3	-	27260156	CORL105	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.1339285149239765	[559]	[688,629,966,630]	2	hSpCas9	negative selection	6505194
48656753	48656776	3	+	27260156	CORL105	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.007338233378467729	[929]	[903,1067,1221,1153]	0	hSpCas9	negative selection	6505195
48656176	48656199	3	-	27260156	CORL105	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.32355144020403886	[284]	[466,461,378,356]	6	hSpCas9	negative selection	6569468
48656178	48656201	3	+	27260156	CORL105	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.7763745905284616	[315]	[261,185,252,170]	-8	hSpCas9	negative selection	6569469
48657322	48657345	3	+	27260156	CORL105	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.37465158943800647	[382]	[409,321,301,344]	-6	hSpCas9	negative selection	6569470
48661542	48661565	3	-	27260156	HS294T	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.12072826061207467	[452]	[110,219,157,156]	-2	hSpCas9	negative selection	6626444
48661461	48661484	3	-	27260156	HS294T	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.5604615297177127	[559]	[137,156,131,162]	-7	hSpCas9	negative selection	6626445
48656753	48656776	3	+	27260156	HS294T	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.07221369379335763	[929]	[302,257,488,319]	-1	hSpCas9	negative selection	6626446
48656176	48656199	3	-	27260156	HS294T	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.4413233826955642	[284]	[137,232,86,135]	6	hSpCas9	negative selection	6690719
48656178	48656201	3	+	27260156	HS294T	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.9199402642856478	[315]	[28,26,28,46]	-9	hSpCas9	negative selection	6690720
48657322	48657345	3	+	27260156	HS294T	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.36912480258047475	[382]	[158,244,178,180]	5	hSpCas9	negative selection	6690721
48661542	48661565	3	-	27260156	HCC44	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.2780570403375229	[452]	[381,318,839,234]	-4	hSpCas9	negative selection	6747695
48661461	48661484	3	-	27260156	HCC44	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.020901278997452644	[559]	[497,640,677,737]	0	hSpCas9	negative selection	6747696
48656753	48656776	3	+	27260156	HCC44	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.5934324160590427	[929]	[695,582,958,608]	-7	hSpCas9	negative selection	6747697
48656176	48656199	3	-	27260156	HCC44	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	-0.19315424075259002	[284]	[320,242,214,341]	-3	hSpCas9	negative selection	6811970
48656178	48656201	3	+	27260156	HCC44	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.1758339680062784	[315]	[188,50,345,97]	-9	hSpCas9	negative selection	6811971
48657322	48657345	3	+	27260156	HCC44	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.10021390796306762	[382]	[526,248,574,554]	1	hSpCas9	negative selection	6811972
48661542	48661565	3	-	27260156	G402	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.48018097688576517	[452]	[578,899,1002,587]	6	hSpCas9	negative selection	6868946
48661461	48661484	3	-	27260156	G402	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.30987109142349845	[559]	[1322,581,724,809]	4	hSpCas9	negative selection	6868947
48656753	48656776	3	+	27260156	G402	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.3540585944213879	[929]	[710,904,884,1015]	-4	hSpCas9	negative selection	6868948
48656176	48656199	3	-	27260156	G402	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.15483828339643002	[284]	[493,530,202,344]	2	hSpCas9	negative selection	6933221
48656178	48656201	3	+	27260156	G402	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.7148167197448922	[315]	[151,236,70,455]	-7	hSpCas9	negative selection	6933222
48657322	48657345	3	+	27260156	G402	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.33912510512760335	[382]	[1417,172,412,459]	4	hSpCas9	negative selection	6933223
48661542	48661565	3	-	27260156	L33	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.231294918790362	[452]	[467,107,256,400]	-5	hSpCas9	negative selection	6990197
48661461	48661484	3	-	27260156	L33	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.16292609036320782	[559]	[542,233,285,430]	-4	hSpCas9	negative selection	6990198
48656753	48656776	3	+	27260156	L33	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	0.03243560767082698	[929]	[875,410,533,1075]	0	hSpCas9	negative selection	6990199
48656176	48656199	3	-	27260156	L33	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.17493615032328602	[284]	[308,123,229,309]	4	hSpCas9	negative selection	7054472
48656178	48656201	3	+	27260156	L33	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.1515817346370325	[315]	[169,38,85,165]	-9	hSpCas9	negative selection	7054473
48657322	48657345	3	+	27260156	L33	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.31120052280484467	[382]	[221,173,161,331]	-6	hSpCas9	negative selection	7054474
48661542	48661565	3	-	27260156	K562	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.7226879301956738	[452]	[845,748,833,285]	8	hSpCas9	negative selection	7111448
48661461	48661484	3	-	27260156	K562	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.10662945683868927	[559]	[493,328,555,460]	-1	hSpCas9	negative selection	7111449
48656753	48656776	3	+	27260156	K562	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.6430616862951207	[929]	[620,365,361,736]	-6	hSpCas9	negative selection	7111450
48656176	48656199	3	-	27260156	K562	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.2723666611447554	[284]	[440,469,152,189]	3	hSpCas9	negative selection	7175723
48656178	48656201	3	+	27260156	K562	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.4051125513196284	[315]	[308,143,85,300]	-5	hSpCas9	negative selection	7175724
48657322	48657345	3	+	27260156	K562	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.26487268582495427	[382]	[311,606,501,233]	3	hSpCas9	negative selection	7175725
48661542	48661565	3	-	27260156	HT29	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.02761317520213183	[452]	[657,570,580,452]	0	hSpCas9	negative selection	7232699
48661461	48661484	3	-	27260156	HT29	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.308639140098525	[559]	[496,705,532,476]	-5	hSpCas9	negative selection	7232700
48656753	48656776	3	+	27260156	HT29	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	0.10912987922118123	[929]	[1487,1083,1224,1095]	2	hSpCas9	negative selection	7232701
48656176	48656199	3	-	27260156	HT29	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.13164532581824684	[284]	[372,301,531,309]	2	hSpCas9	negative selection	7296974
48656178	48656201	3	+	27260156	HT29	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.6471998147123097	[315]	[183,307,197,284]	-8	hSpCas9	negative selection	7296975
48657322	48657345	3	+	27260156	HT29	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.05641306274529828	[382]	[518,720,401,332]	1	hSpCas9	negative selection	7296976
48661542	48661565	3	-	27260156	MHHES1	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.20501748355173474	[452]	[389,719,678,548]	4	hSpCas9	negative selection	7353950
48661461	48661484	3	-	27260156	MHHES1	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.22580232517764473	[559]	[623,438,492,578]	-4	hSpCas9	negative selection	7353951
48656753	48656776	3	+	27260156	MHHES1	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	0.18082948310139035	[929]	[1510,1339,1199,813]	3	hSpCas9	negative selection	7353952
48656176	48656199	3	-	27260156	MHHES1	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.47485251618542273	[284]	[637,519,294,368]	8	hSpCas9	negative selection	7418225
48656178	48656201	3	+	27260156	MHHES1	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.9641986379416754	[315]	[121,256,130,208]	-9	hSpCas9	negative selection	7418226
48657322	48657345	3	+	27260156	MHHES1	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.11566808550153379	[382]	[473,398,482,267]	-2	hSpCas9	negative selection	7418227
48661542	48661565	3	-	27260156	MEWO	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.30272881918177136	[452]	[522,564,479]	6	hSpCas9	negative selection	7475201
48661461	48661484	3	-	27260156	MEWO	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.001800095298203741	[559]	[547,550,478]	0	hSpCas9	negative selection	7475202
48656753	48656776	3	+	27260156	MEWO	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.09888156977223361	[929]	[1178,636,692]	-2	hSpCas9	negative selection	7475203
48656176	48656199	3	-	27260156	MEWO	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	-0.1929158675053062	[284]	[367,199,157]	-4	hSpCas9	negative selection	7539476
48656178	48656201	3	+	27260156	MEWO	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.9569397741180568	[315]	[198,132,133]	-9	hSpCas9	negative selection	7539477
48657322	48657345	3	+	27260156	MEWO	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.08160099667722781	[382]	[264,442,292]	-2	hSpCas9	negative selection	7539478
48661542	48661565	3	-	27260156	LNCAPCLONEFGC	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.05282552076258338	[452]	[357,287,615,478]	0	hSpCas9	negative selection	7596452
48661461	48661484	3	-	27260156	LNCAPCLONEFGC	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.09007058819713942	[559]	[441,485,600,644]	1	hSpCas9	negative selection	7596453
48656753	48656776	3	+	27260156	LNCAPCLONEFGC	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.3485046048964836	[929]	[691,603,840,538]	-5	hSpCas9	negative selection	7596454
48656176	48656199	3	-	27260156	LNCAPCLONEFGC	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.16046296981132957	[284]	[220,214,482,269]	2	hSpCas9	negative selection	7660727
48656178	48656201	3	+	27260156	LNCAPCLONEFGC	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.55893590690209	[315]	[178,249,202,142]	-7	hSpCas9	negative selection	7660728
48657322	48657345	3	+	27260156	LNCAPCLONEFGC	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.20934098211448415	[382]	[313,216,290,381]	-3	hSpCas9	negative selection	7660729
48661542	48661565	3	-	27260156	PANC0327	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.13547651706774388	[452]	[280,524,439,497]	2	hSpCas9	negative selection	7717703
48661461	48661484	3	-	27260156	PANC0327	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.07490969693537017	[559]	[470,209,665,575]	-1	hSpCas9	negative selection	7717704
48656753	48656776	3	+	27260156	PANC0327	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.3297601690015085	[929]	[875,556,642,583]	-5	hSpCas9	negative selection	7717705
48656176	48656199	3	-	27260156	PANC0327	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	-0.43247821379440154	[284]	[224,135,173,224]	-6	hSpCas9	negative selection	7781978
48656178	48656201	3	+	27260156	PANC0327	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.24985859728407478	[315]	[151,109,475,215]	-4	hSpCas9	negative selection	7781979
48657322	48657345	3	+	27260156	PANC0327	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.036096382149695794	[382]	[308,362,283,433]	0	hSpCas9	negative selection	7781980
48661542	48661565	3	-	27260156	NCIH2009	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.27248956980174377	[452]	[1070,860,418]	4	hSpCas9	negative selection	7838954
48661461	48661484	3	-	27260156	NCIH2009	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.0037858102975072416	[559]	[1045,825,530]	0	hSpCas9	negative selection	7838955
48656753	48656776	3	+	27260156	NCIH2009	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.2974439506419171	[929]	[1127,1057,997]	-4	hSpCas9	negative selection	7838956
48656176	48656199	3	-	27260156	NCIH2009	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.1387198167026117	[284]	[520,422,386]	2	hSpCas9	negative selection	7903229
48656178	48656201	3	+	27260156	NCIH2009	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.5576381880345422	[315]	[219,123,119]	-9	hSpCas9	negative selection	7903230
48657322	48657345	3	+	27260156	NCIH2009	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.1888622261918026	[382]	[654,316,474]	-3	hSpCas9	negative selection	7903231
48661542	48661565	3	-	27260156	NCIH1373	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.5039238876050037	[452]	[1167,682,484,160]	5	hSpCas9	negative selection	7960205
48661461	48661484	3	-	27260156	NCIH1373	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.14512693956067718	[559]	[987,526,367,256]	1	hSpCas9	negative selection	7960206
48656753	48656776	3	+	27260156	NCIH1373	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.3179002146018095	[929]	[1117,573,784,247]	-3	hSpCas9	negative selection	7960207
48656176	48656199	3	-	27260156	NCIH1373	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.8246185903373267	[284]	[1013,443,417,121]	7	hSpCas9	negative selection	8024480
48656178	48656201	3	+	27260156	NCIH1373	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.9780625359224866	[315]	[177,22,94,21]	-9	hSpCas9	negative selection	8024481
48657322	48657345	3	+	27260156	NCIH1373	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.5702474712189637	[382]	[756,849,424,132]	5	hSpCas9	negative selection	8024482
48661542	48661565	3	-	27260156	PATU8902	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.7632637166042109	[452]	[1004,855,1160,1250]	7	hSpCas9	negative selection	8081456
48661461	48661484	3	-	27260156	PATU8902	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.48135265779765735	[559]	[469,253,688,813]	-5	hSpCas9	negative selection	8081457
48656753	48656776	3	+	27260156	PATU8902	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	0.05515079340659823	[929]	[1992,1214,635,1751]	0	hSpCas9	negative selection	8081458
48656176	48656199	3	-	27260156	PATU8902	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.39151723037131875	[284]	[292,609,312,973]	4	hSpCas9	negative selection	8145731
48656178	48656201	3	+	27260156	PATU8902	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.7632615269081187	[315]	[410,149,106,423]	-6	hSpCas9	negative selection	8145732
48657322	48657345	3	+	27260156	PATU8902	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	0.30305976310224275	[382]	[848,556,309,1044]	3	hSpCas9	negative selection	8145733
48661542	48661565	3	-	27260156	PANC1	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.029697250054950407	[452]	[345,474,446,340]	0	hSpCas9	negative selection	8202707
48661461	48661484	3	-	27260156	PANC1	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.748469865744644	[559]	[230,350,326,251]	-8	hSpCas9	negative selection	8202708
48656753	48656776	3	+	27260156	PANC1	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.6314576672387264	[929]	[474,651,451,504]	-7	hSpCas9	negative selection	8202709
48656176	48656199	3	-	27260156	PANC1	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.11345065276923738	[284]	[160,446,292,203]	1	hSpCas9	negative selection	8266982
48656178	48656201	3	+	27260156	PANC1	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.9731579242564041	[315]	[100,168,169,120]	-8	hSpCas9	negative selection	8266983
48657322	48657345	3	+	27260156	PANC1	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.34213660445734173	[382]	[117,314,382,236]	-5	hSpCas9	negative selection	8266984
48661542	48661565	3	-	27260156	PANC0813	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.3607092307017205	[452]	[851,670,817,421]	6	hSpCas9	negative selection	8323958
48661461	48661484	3	-	27260156	PANC0813	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.4241911601012647	[559]	[517,452,625,372]	-6	hSpCas9	negative selection	8323959
48656753	48656776	3	+	27260156	PANC0813	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.2352253804272304	[929]	[1255,841,695,944]	-4	hSpCas9	negative selection	8323960
48656176	48656199	3	-	27260156	PANC0813	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.05151793407801308	[284]	[484,364,300,253]	0	hSpCas9	negative selection	8388233
48656178	48656201	3	+	27260156	PANC0813	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.0133418363167128	[315]	[256,148,222,116]	-8	hSpCas9	negative selection	8388234
48657322	48657345	3	+	27260156	PANC0813	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.27554097558085977	[382]	[520,341,326,312]	-4	hSpCas9	negative selection	8388235
48661542	48661565	3	-	27260156	RDES	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.13189141910387817	[452]	[492,480,643,694]	2	hSpCas9	negative selection	8445209
48661461	48661484	3	-	27260156	RDES	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.8643208570327787	[559]	[290,284,421,442]	-8	hSpCas9	negative selection	8445210
48656753	48656776	3	+	27260156	RDES	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.3791700359574883	[929]	[764,813,780,929]	-6	hSpCas9	negative selection	8445211
48656176	48656199	3	-	27260156	RDES	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.12451511747710164	[284]	[311,350,278,505]	2	hSpCas9	negative selection	8509484
48656178	48656201	3	+	27260156	RDES	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.826342089941573	[315]	[151,203,234,240]	-8	hSpCas9	negative selection	8509485
48657322	48657345	3	+	27260156	RDES	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.026589064204515955	[382]	[343,488,406,498]	0	hSpCas9	negative selection	8509486
48661542	48661565	3	-	27260156	PC3	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.03205480106630847	[452]	[237,368,709,617]	0	hSpCas9	negative selection	8566460
48661461	48661484	3	-	27260156	PC3	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.007435366725325632	[559]	[366,493,919,638]	0	hSpCas9	negative selection	8566461
48656753	48656776	3	+	27260156	PC3	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.17900026260092716	[929]	[460,971,1340,776]	-4	hSpCas9	negative selection	8566462
48656176	48656199	3	-	27260156	PC3	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	-0.03576524541995929	[284]	[147,362,381,283]	-1	hSpCas9	negative selection	8630735
48656178	48656201	3	+	27260156	PC3	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.7518737026327156	[315]	[118,137,402,186]	-9	hSpCas9	negative selection	8630736
48657322	48657345	3	+	27260156	PC3	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.1497788069358526	[382]	[226,270,435,505]	-3	hSpCas9	negative selection	8630737
48661542	48661565	3	-	27260156	PATU8988T	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.6189576269059344	[452]	[685,909,448,668]	8	hSpCas9	negative selection	8687711
48661461	48661484	3	-	27260156	PATU8988T	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.27846261322691535	[559]	[686,787,435,735]	5	hSpCas9	negative selection	8687712
48656753	48656776	3	+	27260156	PATU8988T	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.05756549073980344	[929]	[773,960,961,755]	-1	hSpCas9	negative selection	8687713
48656176	48656199	3	-	27260156	PATU8988T	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.1145454009519119	[284]	[403,251,284,242]	2	hSpCas9	negative selection	8751986
48656178	48656201	3	+	27260156	PATU8988T	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.0203292848341707	[315]	[43,104,323,119]	-9	hSpCas9	negative selection	8751987
48657322	48657345	3	+	27260156	PATU8988T	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.4004128595721762	[382]	[240,404,160,331]	-6	hSpCas9	negative selection	8751988
48661542	48661565	3	-	27260156	T47D	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.13417440469391279	[452]	[569,538,572,639]	3	hSpCas9	negative selection	8808962
48661461	48661484	3	-	27260156	T47D	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.005942303980213837	[559]	[642,597,684,699]	0	hSpCas9	negative selection	8808963
48656753	48656776	3	+	27260156	T47D	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.10762500476931325	[929]	[965,847,1073,1150]	-2	hSpCas9	negative selection	8808964
48656176	48656199	3	-	27260156	T47D	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.09283518429123039	[284]	[396,319,357,343]	2	hSpCas9	negative selection	8873237
48656178	48656201	3	+	27260156	T47D	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.8375957917133001	[315]	[242,175,196,210]	-9	hSpCas9	negative selection	8873238
48657322	48657345	3	+	27260156	T47D	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.26746015907536225	[382]	[386,367,359,367]	-5	hSpCas9	negative selection	8873239
48661542	48661565	3	-	27260156	SU8686	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.13253374470459392	[452]	[320,549,413,728]	2	hSpCas9	negative selection	8930213
48661461	48661484	3	-	27260156	SU8686	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.7865488322006179	[559]	[293,278,388,335]	-8	hSpCas9	negative selection	8930214
48656753	48656776	3	+	27260156	SU8686	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.07010971802576327	[929]	[871,706,985,984]	-1	hSpCas9	negative selection	8930215
48656176	48656199	3	-	27260156	SU8686	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.032414188436695635	[284]	[238,201,408,330]	0	hSpCas9	negative selection	8994488
48656178	48656201	3	+	27260156	SU8686	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.959854898297011	[315]	[111,165,131,251]	-8	hSpCas9	negative selection	8994489
48657322	48657345	3	+	27260156	SU8686	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.014589636538882289	[382]	[319,347,440,408]	0	hSpCas9	negative selection	8994490
48661542	48661565	3	-	27260156	SKES1	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.07990254704785893	[452]	[441,627,372,476]	1	hSpCas9	negative selection	9051464
48661461	48661484	3	-	27260156	SKES1	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.03863108689953201	[559]	[593,586,489,514]	-1	hSpCas9	negative selection	9051465
48656753	48656776	3	+	27260156	SKES1	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.08913549444036206	[929]	[858,1233,693,750]	-2	hSpCas9	negative selection	9051466
48656176	48656199	3	-	27260156	SKES1	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.038721749472035105	[284]	[258,331,236,332]	0	hSpCas9	negative selection	9115739
48656178	48656201	3	+	27260156	SKES1	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.1131375041448404	[315]	[104,99,205,156]	-9	hSpCas9	negative selection	9115740
48657322	48657345	3	+	27260156	SKES1	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.003867780136239729	[382]	[547,360,381,263]	0	hSpCas9	negative selection	9115741
48661542	48661565	3	-	27260156	TOV112D	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.06258855699835741	[452]	[395,684,460,399]	1	hSpCas9	negative selection	9172715
48661461	48661484	3	-	27260156	TOV112D	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	0.08458869266655428	[559]	[604,951,432,479]	1	hSpCas9	negative selection	9172716
48656753	48656776	3	+	27260156	TOV112D	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.28957929051793085	[929]	[816,934,647,695]	-5	hSpCas9	negative selection	9172717
48656176	48656199	3	-	27260156	TOV112D	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.10793921918542537	[284]	[308,151,394,334]	2	hSpCas9	negative selection	9236990
48656178	48656201	3	+	27260156	TOV112D	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-1.2404652868321522	[315]	[169,153,101,117]	-9	hSpCas9	negative selection	9236991
48657322	48657345	3	+	27260156	TOV112D	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.45930596043447625	[382]	[342,196,326,234]	-7	hSpCas9	negative selection	9236992
48661542	48661565	3	-	27260156	TC71	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	-0.09719580028695049	[452]	[434,401,392,596]	-2	hSpCas9	negative selection	9293966
48661461	48661484	3	-	27260156	TC71	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.18401411195636666	[559]	[437,629,557,485]	-5	hSpCas9	negative selection	9293967
48656753	48656776	3	+	27260156	TC71	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.18976357751339912	[929]	[826,833,862,979]	-5	hSpCas9	negative selection	9293968
48656176	48656199	3	-	27260156	TC71	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	0.013157225353041535	[284]	[269,406,239,319]	0	hSpCas9	negative selection	9358241
48656178	48656201	3	+	27260156	TC71	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.8278401004010152	[315]	[226,220,161,150]	-9	hSpCas9	negative selection	9358242
48657322	48657345	3	+	27260156	TC71	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.11970827479994195	[382]	[431,338,388,347]	-3	hSpCas9	negative selection	9358243
48661542	48661565	3	-	27260156	TC32	viability	CGGGCGCCTAGTCTACTCGCTGG	CELSR3	ENSG00000008300	0.02409253166031284	[452]	[420,248,569,569]	0	hSpCas9	negative selection	9415217
48661461	48661484	3	-	27260156	TC32	viability	TATCCGTACGGCGGCAGCTCTGG	CELSR3	ENSG00000008300	-0.3926773525533952	[559]	[459,249,631,322]	-6	hSpCas9	negative selection	9415218
48656753	48656776	3	+	27260156	TC32	viability	TCCGCCGTTGCGACATGGGTTGG	CELSR3	ENSG00000008300	-0.1898406427914181	[929]	[686,495,1032,975]	-3	hSpCas9	negative selection	9415219
48656176	48656199	3	-	27260156	TC32	viability	AGTTCGTTCGTCATGTTTCGCGG	CELSR3	ENSG00000008300	-0.14403532976822675	[284]	[234,216,272,244]	-3	hSpCas9	negative selection	9479492
48656178	48656201	3	+	27260156	TC32	viability	GCGAAACATGACGAACGAACTGG	CELSR3	ENSG00000008300	-0.71126198008528	[315]	[149,41,331,281]	-8	hSpCas9	negative selection	9479493
48657322	48657345	3	+	27260156	TC32	viability	ACTGCGCCGTCACGCTGTGCAGG	CELSR3	ENSG00000008300	-0.05021932689018316	[382]	[257,241,571,391]	-1	hSpCas9	negative selection	9479494
48655114	48655137	3	-	27869803	HPAFII	viability after 27 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	1.1401343986969281	[192]	[203,239,NaN]	8	hSpCas9	negative selection	9585202
48655376	48655399	3	+	27869803	HPAFII	viability after 27 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	0.6645460485419097	[53]	[74,19,NaN]	5	hSpCas9	negative selection	9585203
48655833	48655856	3	+	27869803	HPAFII	viability after 27 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.9138782585915017	[778]	[763,777,NaN]	7	hSpCas9	negative selection	9585204
48656183	48656206	3	+	27869803	HPAFII	viability after 27 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.38603861893608904	[180]	[110,40,NaN]	-3	hSpCas9	negative selection	9585205
48656893	48656916	3	+	27869803	HPAFII	viability after 27 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.7294968649443131	[427]	[509,258,NaN]	6	hSpCas9	negative selection	9585206
48661925	48661948	3	+	27869803	HPAFII	viability after 27 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.8120918855017272	[387]	[137,97,NaN]	-5	hSpCas9	negative selection	9585207
48655114	48655137	3	-	27869803	HPAFII	viability after 15 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	1.2255409982742709	[192]	[772,305,NaN]	9	hSpCas9	negative selection	9667651
48655376	48655399	3	+	27869803	HPAFII	viability after 15 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	0.8675429419083027	[53]	[161,70,NaN]	8	hSpCas9	negative selection	9667652
48655833	48655856	3	+	27869803	HPAFII	viability after 15 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.6115520021359131	[778]	[1613,1070,NaN]	7	hSpCas9	negative selection	9667653
48656183	48656206	3	+	27869803	HPAFII	viability after 15 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.5650562579352391	[180]	[157,114,NaN]	-6	hSpCas9	negative selection	9667654
48656893	48656916	3	+	27869803	HPAFII	viability after 15 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.29705822405372306	[427]	[603,540,NaN]	3	hSpCas9	negative selection	9667655
48661925	48661948	3	+	27869803	HPAFII	viability after 15 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.13309274320713538	[387]	[526,288,NaN]	-1	hSpCas9	negative selection	9667656
48655114	48655137	3	-	27869803	ASPC1	viability after 36 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.12408202093084517	[612]	[205,266,222]	1	hSpCas9	negative selection	9750100
48655376	48655399	3	+	27869803	ASPC1	viability after 36 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	0.6702907038927304	[137]	[5,148,67]	6	hSpCas9	negative selection	9750101
48655833	48655856	3	+	27869803	ASPC1	viability after 36 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	-0.4331284199067056	[1782]	[316,406,599]	-4	hSpCas9	negative selection	9750102
48656183	48656206	3	+	27869803	ASPC1	viability after 36 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.36580945777331775	[425]	[46,262,44]	-4	hSpCas9	negative selection	9750103
48656893	48656916	3	+	27869803	ASPC1	viability after 36 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.7762504270091471	[1081]	[792,702,492]	7	hSpCas9	negative selection	9750104
48661925	48661948	3	+	27869803	ASPC1	viability after 36 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.30843879737652824	[1170]	[164,346,428]	-3	hSpCas9	negative selection	9750105
48655114	48655137	3	-	27869803	PATU8988S	viability after 35 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.45667155603797394	[470]	[186,333,NaN]	5	hSpCas9	negative selection	9832549
48655376	48655399	3	+	27869803	PATU8988S	viability after 35 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-2.1099391261879292	[144]	[25,0,NaN]	-9	hSpCas9	negative selection	9832550
48655833	48655856	3	+	27869803	PATU8988S	viability after 35 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.4685691548468307	[1566]	[561,1185,NaN]	5	hSpCas9	negative selection	9832551
48656183	48656206	3	+	27869803	PATU8988S	viability after 35 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	0.2556680106599969	[305]	[206,86,NaN]	3	hSpCas9	negative selection	9832552
48656893	48656916	3	+	27869803	PATU8988S	viability after 35 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	-0.08081019287816094	[925]	[190,514,NaN]	-1	hSpCas9	negative selection	9832553
48661925	48661948	3	+	27869803	PATU8988S	viability after 35 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.15086469781962264	[788]	[381,189,NaN]	-1	hSpCas9	negative selection	9832554
48655114	48655137	3	-	27869803	PATU8988S	viability after 31 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.54480856548215	[470]	[174,399,NaN]	6	hSpCas9	negative selection	9914998
48655376	48655399	3	+	27869803	PATU8988S	viability after 31 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	-0.17653334900530204	[144]	[44,58,NaN]	-2	hSpCas9	negative selection	9914999
48655833	48655856	3	+	27869803	PATU8988S	viability after 31 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.390884603688362	[1566]	[414,1333,NaN]	5	hSpCas9	negative selection	9915000
48656183	48656206	3	+	27869803	PATU8988S	viability after 31 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.14572954944519567	[305]	[170,32,NaN]	-2	hSpCas9	negative selection	9915001
48656893	48656916	3	+	27869803	PATU8988S	viability after 31 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.04632747627412992	[925]	[214,592,NaN]	0	hSpCas9	negative selection	9915002
48661925	48661948	3	+	27869803	PATU8988S	viability after 31 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.23395195605674562	[788]	[230,313,NaN]	-3	hSpCas9	negative selection	9915003
48655114	48655137	3	-	27869803	HPAFII	viability after 35 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.8782179039298175	[192]	[188,168,NaN]	6	hSpCas9	negative selection	9997447
48655376	48655399	3	+	27869803	HPAFII	viability after 35 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	1.1789119392556195	[53]	[83,36,NaN]	7	hSpCas9	negative selection	9997448
48655833	48655856	3	+	27869803	HPAFII	viability after 35 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	1.0704609518877948	[778]	[537,1154,NaN]	7	hSpCas9	negative selection	9997449
48656183	48656206	3	+	27869803	HPAFII	viability after 35 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-0.9737627033488333	[180]	[64,25,NaN]	-5	hSpCas9	negative selection	9997450
48656893	48656916	3	+	27869803	HPAFII	viability after 35 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.6226517429354922	[427]	[382,277,NaN]	4	hSpCas9	negative selection	9997451
48661925	48661948	3	+	27869803	HPAFII	viability after 35 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.7665443486500638	[387]	[98,133,NaN]	-4	hSpCas9	negative selection	9997452
48655114	48655137	3	-	27869803	HPAFII	viability after 31 days	GGATGATTGTGATGTGGCCGTGG	CELSR3	ENSG00000008300	0.9995656954457126	[192]	[217,214,NaN]	7	hSpCas9	negative selection	10079896
48655376	48655399	3	+	27869803	HPAFII	viability after 31 days	ACCACGGTGTTGGATTCACCTGG	CELSR3	ENSG00000008300	1.3992520178408687	[53]	[111,44,NaN]	8	hSpCas9	negative selection	10079897
48655833	48655856	3	+	27869803	HPAFII	viability after 31 days	CTGCTGCACTGTCGCGAACCTGG	CELSR3	ENSG00000008300	0.7690989500572678	[778]	[522,986,NaN]	5	hSpCas9	negative selection	10079898
48656183	48656206	3	+	27869803	HPAFII	viability after 31 days	ACATGACGAACGAACTGGGCGGG	CELSR3	ENSG00000008300	-1.359566708871497	[180]	[74,0,NaN]	-7	hSpCas9	negative selection	10079899
48656893	48656916	3	+	27869803	HPAFII	viability after 31 days	AGGGCGCGGACGAGTCAAAGCGG	CELSR3	ENSG00000008300	0.7287618418375036	[427]	[432,359,NaN]	5	hSpCas9	negative selection	10079900
48661925	48661948	3	+	27869803	HPAFII	viability after 31 days	CCTGGAAGACAGTTCCGCCGGGG	CELSR3	ENSG00000008300	-0.2924880879146639	[387]	[161,194,NaN]	-2	hSpCas9	negative selection	10079901
48650902	48650925	3	+	28162770	P31FUJ	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	-0.1756068028328355	[271]	[282]	-2	hSpCas9	negative selection	10131507
48661690	48661713	3	+	28162770	P31FUJ	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	0.6282213824368109	[97]	[177]	7	hSpCas9	negative selection	10131508
48647954	48647977	3	-	28162770	P31FUJ	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.6828351250494262	[305]	[111]	-8	hSpCas9	negative selection	10131509
48643652	48643675	3	+	28162770	P31FUJ	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	-0.3244326798799466	[129]	[121]	-3	hSpCas9	negative selection	10131510
48642783	48642806	3	+	28162770	P31FUJ	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-0.4993171789831343	[82]	[68]	-4	hSpCas9	negative selection	10131511
48640449	48640472	3	+	28162770	P31FUJ	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.04935606331844733	[117]	[133]	0	hSpCas9	negative selection	10131512
48639900	48639923	3	-	28162770	P31FUJ	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-0.14260439544280024	[92]	[98]	-1	hSpCas9	negative selection	10131513
48662462	48662485	3	-	28162770	P31FUJ	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.15911805523981168	[172]	[226]	1	hSpCas9	negative selection	10131514
48662060	48662083	3	-	28162770	P31FUJ	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.6595888214990246	[479]	[890]	7	hSpCas9	negative selection	10131515
48661767	48661790	3	+	28162770	P31FUJ	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-4.139692800022897	[14]	[0]	-9	hSpCas9	negative selection	10131516
48650902	48650925	3	+	28162770	TF1	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10300873
48661690	48661713	3	+	28162770	TF1	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10300874
48647954	48647977	3	-	28162770	TF1	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10300875
48643652	48643675	3	+	28162770	TF1	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10300876
48642783	48642806	3	+	28162770	TF1	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10300877
48640449	48640472	3	+	28162770	TF1	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10300878
48639900	48639923	3	-	28162770	TF1	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10300879
48662462	48662485	3	-	28162770	TF1	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10300880
48662060	48662083	3	-	28162770	TF1	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	NaN	[NaN]	[480]	1	hSpCas9	negative selection	10300881
48661767	48661790	3	+	28162770	TF1	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10300882
48650902	48650925	3	+	28162770	SKM1	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	-0.30575194738486366	[85]	[122]	-3	hSpCas9	negative selection	10470239
48661690	48661713	3	+	28162770	SKM1	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	2.229660421800487	[23]	[198]	9	hSpCas9	negative selection	10470240
48647954	48647977	3	-	28162770	SKM1	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.071979951030353	[87]	[73]	-7	hSpCas9	negative selection	10470241
48643652	48643675	3	+	28162770	SKM1	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.2934755193979304	[35]	[77]	3	hSpCas9	negative selection	10470242
48642783	48642806	3	+	28162770	SKM1	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-1.5138794026596734	[20]	[12]	-7	hSpCas9	negative selection	10470243
48640449	48640472	3	+	28162770	SKM1	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.8220016980220055	[30]	[30]	-6	hSpCas9	negative selection	10470244
48639900	48639923	3	-	28162770	SKM1	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-1.269460674993227	[14]	[10]	-7	hSpCas9	negative selection	10470245
48662462	48662485	3	-	28162770	SKM1	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.21647244979263014	[36]	[75]	2	hSpCas9	negative selection	10470246
48662060	48662083	3	-	28162770	SKM1	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.3381328002274975	[114]	[256]	3	hSpCas9	negative selection	10470247
48661767	48661790	3	+	28162770	SKM1	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-3.8220016980220053	[7]	[0]	-9	hSpCas9	negative selection	10470248
48650902	48650925	3	+	28162770	SKM1	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	-0.30575194738486366	[85]	[122]	-3	hSpCas9	negative selection	10639605
48661690	48661713	3	+	28162770	SKM1	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	2.229660421800487	[23]	[198]	9	hSpCas9	negative selection	10639606
48647954	48647977	3	-	28162770	SKM1	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.071979951030353	[87]	[73]	-7	hSpCas9	negative selection	10639607
48643652	48643675	3	+	28162770	SKM1	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.2934755193979304	[35]	[77]	3	hSpCas9	negative selection	10639608
48642783	48642806	3	+	28162770	SKM1	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-1.5138794026596734	[20]	[12]	-7	hSpCas9	negative selection	10639609
48640449	48640472	3	+	28162770	SKM1	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.8220016980220055	[30]	[30]	-6	hSpCas9	negative selection	10639610
48639900	48639923	3	-	28162770	SKM1	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-1.269460674993227	[14]	[10]	-7	hSpCas9	negative selection	10639611
48662462	48662485	3	-	28162770	SKM1	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.21647244979263014	[36]	[75]	2	hSpCas9	negative selection	10639612
48662060	48662083	3	-	28162770	SKM1	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.3381328002274975	[114]	[256]	3	hSpCas9	negative selection	10639613
48661767	48661790	3	+	28162770	SKM1	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-3.8220016980220053	[7]	[0]	-9	hSpCas9	negative selection	10639614
48650902	48650925	3	+	28162770	PL21	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.4765235739821337	[250]	[151]	4	hSpCas9	negative selection	10808971
48661690	48661713	3	+	28162770	PL21	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	-0.12178848039804202	[64]	[25]	-1	hSpCas9	negative selection	10808972
48647954	48647977	3	-	28162770	PL21	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.4187702181551738	[343]	[55]	-7	hSpCas9	negative selection	10808973
48643652	48643675	3	+	28162770	PL21	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.9848716275862539	[100]	[86]	8	hSpCas9	negative selection	10808974
48642783	48642806	3	+	28162770	PL21	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-0.31832747444492926	[105]	[36]	-2	hSpCas9	negative selection	10808975
48640449	48640472	3	+	28162770	PL21	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	0.25391087093030085	[78]	[40]	2	hSpCas9	negative selection	10808976
48639900	48639923	3	-	28162770	PL21	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	0.007494536546924113	[31]	[13]	0	hSpCas9	negative selection	10808977
48662462	48662485	3	-	28162770	PL21	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	-1.3562537340350649	[99]	[16]	-7	hSpCas9	negative selection	10808978
48662060	48662083	3	-	28162770	PL21	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.518109695807999	[291]	[181]	4	hSpCas9	negative selection	10808979
48661767	48661790	3	+	28162770	PL21	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-2.6072153075682842	[13]	[0]	-9	hSpCas9	negative selection	10808980
48650902	48650925	3	+	28162770	P31FUJ	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	-0.1756068028328355	[271]	[282]	-2	hSpCas9	negative selection	10978337
48661690	48661713	3	+	28162770	P31FUJ	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	0.6282213824368109	[97]	[177]	7	hSpCas9	negative selection	10978338
48647954	48647977	3	-	28162770	P31FUJ	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.6828351250494262	[305]	[111]	-8	hSpCas9	negative selection	10978339
48643652	48643675	3	+	28162770	P31FUJ	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	-0.3244326798799466	[129]	[121]	-3	hSpCas9	negative selection	10978340
48642783	48642806	3	+	28162770	P31FUJ	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-0.4993171789831343	[82]	[68]	-4	hSpCas9	negative selection	10978341
48640449	48640472	3	+	28162770	P31FUJ	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.04935606331844733	[117]	[133]	0	hSpCas9	negative selection	10978342
48639900	48639923	3	-	28162770	P31FUJ	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-0.14260439544280024	[92]	[98]	-1	hSpCas9	negative selection	10978343
48662462	48662485	3	-	28162770	P31FUJ	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.15911805523981168	[172]	[226]	1	hSpCas9	negative selection	10978344
48662060	48662083	3	-	28162770	P31FUJ	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.6595888214990246	[479]	[890]	7	hSpCas9	negative selection	10978345
48661767	48661790	3	+	28162770	P31FUJ	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-4.139692800022897	[14]	[0]	-9	hSpCas9	negative selection	10978346
48650902	48650925	3	+	28162770	OCIAML5	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.20913358557274042	[149]	[312]	1	hSpCas9	negative selection	11147703
48661690	48661713	3	+	28162770	OCIAML5	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	1.218322757027401	[49]	[209]	9	hSpCas9	negative selection	11147704
48647954	48647977	3	-	28162770	OCIAML5	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.2671040701428409	[143]	[107]	-6	hSpCas9	negative selection	11147705
48643652	48643675	3	+	28162770	OCIAML5	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.3936898435379614	[104]	[248]	3	hSpCas9	negative selection	11147706
48642783	48642806	3	+	28162770	OCIAML5	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	0.20451695750237042	[49]	[103]	1	hSpCas9	negative selection	11147707
48640449	48640472	3	+	28162770	OCIAML5	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-1.37562852692101	[68]	[47]	-7	hSpCas9	negative selection	11147708
48639900	48639923	3	-	28162770	OCIAML5	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-2.014337999762874	[46]	[20]	-8	hSpCas9	negative selection	11147709
48662462	48662485	3	-	28162770	OCIAML5	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	1.1533878592281113	[65]	[264]	8	hSpCas9	negative selection	11147710
48662060	48662083	3	-	28162770	OCIAML5	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.7174245210947192	[249]	[741]	6	hSpCas9	negative selection	11147711
48661767	48661790	3	+	28162770	OCIAML5	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	0.9552883511936079	[1]	[6]	8	hSpCas9	negative selection	11147712
48650902	48650925	3	+	28162770	EOL1	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.7277748080054622	[399]	[348]	6	hSpCas9	negative selection	11317069
48661690	48661713	3	+	28162770	EOL1	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	0.8420856113785616	[107]	[101]	7	hSpCas9	negative selection	11317070
48647954	48647977	3	-	28162770	EOL1	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.4733898181945264	[642]	[121]	-7	hSpCas9	negative selection	11317071
48643652	48643675	3	+	28162770	EOL1	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	-0.5009365151434252	[230]	[85]	-4	hSpCas9	negative selection	11317072
48642783	48642806	3	+	28162770	EOL1	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-0.8494485535406388	[170]	[49]	-5	hSpCas9	negative selection	11317073
48640449	48640472	3	+	28162770	EOL1	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.3405942972252507	[136]	[56]	-3	hSpCas9	negative selection	11317074
48639900	48639923	3	-	28162770	EOL1	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-1.9685370245129539	[51]	[6]	-8	hSpCas9	negative selection	11317075
48662462	48662485	3	-	28162770	EOL1	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.522110309071324	[151]	[114]	5	hSpCas9	negative selection	11317076
48662060	48662083	3	-	28162770	EOL1	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.5612253088358461	[547]	[425]	5	hSpCas9	negative selection	11317077
48661767	48661790	3	+	28162770	EOL1	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-3.075452228429466	[15]	[0]	-9	hSpCas9	negative selection	11317078
48650902	48650925	3	+	28162770	MOLM13	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.4098420961767067	[354]	[340]	3	hSpCas9	negative selection	11486435
48661690	48661713	3	+	28162770	MOLM13	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	-0.4251954145389092	[116]	[62]	-3	hSpCas9	negative selection	11486436
48647954	48647977	3	-	28162770	MOLM13	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.0117201190303486	[395]	[141]	-5	hSpCas9	negative selection	11486437
48643652	48643675	3	+	28162770	MOLM13	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	1.7164242176832576	[124]	[296]	9	hSpCas9	negative selection	11486438
48642783	48642806	3	+	28162770	MOLM13	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	1.1534558232041408	[119]	[192]	8	hSpCas9	negative selection	11486439
48640449	48640472	3	+	28162770	MOLM13	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.0312123825227395	[105]	[74]	0	hSpCas9	negative selection	11486440
48639900	48639923	3	-	28162770	MOLM13	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	0.08086625843533168	[33]	[25]	0	hSpCas9	negative selection	11486441
48662462	48662485	3	-	28162770	MOLM13	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	-2.3900916135829933	[115]	[15]	-8	hSpCas9	negative selection	11486442
48662060	48662083	3	-	28162770	MOLM13	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	1.1445544654429707	[512]	[819]	8	hSpCas9	negative selection	11486443
48661767	48661790	3	+	28162770	MOLM13	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-2.269076212621627	[19]	[2]	-8	hSpCas9	negative selection	11486444
48650902	48650925	3	+	28162770	HEL	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.18283381055622328	[380]	[276]	1	hSpCas9	negative selection	11655801
48661690	48661713	3	+	28162770	HEL	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	0.7595524969831069	[82]	[89]	6	hSpCas9	negative selection	11655802
48647954	48647977	3	-	28162770	HEL	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.1897070710200777	[405]	[113]	-6	hSpCas9	negative selection	11655803
48643652	48643675	3	+	28162770	HEL	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	1.0131072819454727	[122]	[158]	8	hSpCas9	negative selection	11655804
48642783	48642806	3	+	28162770	HEL	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	1.3852426097079928	[103]	[173]	9	hSpCas9	negative selection	11655805
48640449	48640472	3	+	28162770	HEL	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	0.006429451278980203	[142]	[91]	0	hSpCas9	negative selection	11655806
48639900	48639923	3	-	28162770	HEL	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-0.8845081708645117	[48]	[16]	-5	hSpCas9	negative selection	11655807
48662462	48662485	3	-	28162770	HEL	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	-1.8353084648042872	[116]	[20]	-7	hSpCas9	negative selection	11655808
48662060	48662083	3	-	28162770	HEL	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	-0.15590365872067358	[453]	[260]	-1	hSpCas9	negative selection	11655809
48661767	48661790	3	+	28162770	HEL	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-3.5271861694419555	[17]	[0]	-9	hSpCas9	negative selection	11655810
48650902	48650925	3	+	28162770	MV411	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.03693880802758087	[301]	[260]	0	hSpCas9	negative selection	11825167
48661690	48661713	3	+	28162770	MV411	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	0.8641089112312699	[74]	[114]	7	hSpCas9	negative selection	11825168
48647954	48647977	3	-	28162770	MV411	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.4574344136735777	[325]	[99]	-7	hSpCas9	negative selection	11825169
48643652	48643675	3	+	28162770	MV411	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	-0.20115250820709518	[115]	[84]	-1	hSpCas9	negative selection	11825170
48642783	48642806	3	+	28162770	MV411	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-0.21822602156603654	[86]	[62]	-2	hSpCas9	negative selection	11825171
48640449	48640472	3	+	28162770	MV411	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-1.2306097460218688	[77]	[27]	-7	hSpCas9	negative selection	11825172
48639900	48639923	3	-	28162770	MV411	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	2.1382084810280166	[23]	[88]	9	hSpCas9	negative selection	11825173
48662462	48662485	3	-	28162770	MV411	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	-0.738887512320148	[104]	[52]	-5	hSpCas9	negative selection	11825174
48662060	48662083	3	-	28162770	MV411	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.22934709379987928	[320]	[316]	2	hSpCas9	negative selection	11825175
48661767	48661790	3	+	28162770	MV411	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-4.074490544104587	[19]	[0]	-9	hSpCas9	negative selection	11825176
48650902	48650925	3	+	28162770	MONOMAC1	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.0037821623285423933	[153]	[176]	0	hSpCas9	negative selection	11994533
48661690	48661713	3	+	28162770	MONOMAC1	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	-0.2901462514510351	[47]	[44]	-3	hSpCas9	negative selection	11994534
48647954	48647977	3	-	28162770	MONOMAC1	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.233378694123274	[200]	[97]	-7	hSpCas9	negative selection	11994535
48643652	48643675	3	+	28162770	MONOMAC1	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	1.5034028710815386	[59]	[194]	9	hSpCas9	negative selection	11994536
48642783	48642806	3	+	28162770	MONOMAC1	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	-0.014833515838804656	[51]	[58]	0	hSpCas9	negative selection	11994537
48640449	48640472	3	+	28162770	MONOMAC1	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.2641510429180908	[65]	[62]	-2	hSpCas9	negative selection	11994538
48639900	48639923	3	-	28162770	MONOMAC1	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-1.8751087521721914	[31]	[9]	-8	hSpCas9	negative selection	11994539
48662462	48662485	3	-	28162770	MONOMAC1	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	0.3879256536616025	[43]	[65]	4	hSpCas9	negative selection	11994540
48662060	48662083	3	-	28162770	MONOMAC1	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.16242330432440988	[257]	[330]	1	hSpCas9	negative selection	11994541
48661767	48661790	3	+	28162770	MONOMAC1	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-1.0901216431430414	[12]	[6]	-7	hSpCas9	negative selection	11994542
48650902	48650925	3	+	28162770	OCIAML2	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	0.9150238672555885	[30]	[323]	8	hSpCas9	negative selection	12163899
48661690	48661713	3	+	28162770	OCIAML2	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	-0.019418713409832367	[31]	[174]	0	hSpCas9	negative selection	12163900
48647954	48647977	3	-	28162770	OCIAML2	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.191770452246685	[67]	[164]	-7	hSpCas9	negative selection	12163901
48643652	48643675	3	+	28162770	OCIAML2	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.14675415317137241	[21]	[134]	1	hSpCas9	negative selection	12163902
48642783	48642806	3	+	28162770	OCIAML2	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	1.318424280072499	[16]	[234]	9	hSpCas9	negative selection	12163903
48640449	48640472	3	+	28162770	OCIAML2	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	-0.09211820198843124	[14]	[77]	-1	hSpCas9	negative selection	12163904
48639900	48639923	3	-	28162770	OCIAML2	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	-1.733664231075955	[8]	[14]	-8	hSpCas9	negative selection	12163905
48662462	48662485	3	-	28162770	OCIAML2	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	-1.108059745857453	[27]	[71]	-6	hSpCas9	negative selection	12163906
48662060	48662083	3	-	28162770	OCIAML2	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.2581684480526466	[61]	[410]	2	hSpCas9	negative selection	12163907
48661767	48661790	3	+	28162770	OCIAML2	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-3.0555923259633175	[2]	[1]	-9	hSpCas9	negative selection	12163908
48650902	48650925	3	+	28162770	OCIAML3	viability	GCTGGCTGTCACCTCTGCGAAGG	CELSR3	ENSG00000008300	1.021543180230416	[69]	[428]	8	hSpCas9	negative selection	12333265
48661690	48661713	3	+	28162770	OCIAML3	viability	AAAGCGTGCCCGGTTCGCCGAGG	CELSR3	ENSG00000008300	-1.0704456842671504	[15]	[22]	-6	hSpCas9	negative selection	12333266
48647954	48647977	3	-	28162770	OCIAML3	viability	GAGCACCCCAGTTCTCCCCGGGG	CELSR3	ENSG00000008300	-1.594007640324163	[73]	[73]	-8	hSpCas9	negative selection	12333267
48643652	48643675	3	+	28162770	OCIAML3	viability	GCAGCAGGAAGGAGCTGCGAAGG	CELSR3	ENSG00000008300	0.2236156171872679	[39]	[140]	2	hSpCas9	negative selection	12333268
48642783	48642806	3	+	28162770	OCIAML3	viability	GGAGCGGGCACTGCTCACAGAGG	CELSR3	ENSG00000008300	0.5164163493694874	[21]	[94]	5	hSpCas9	negative selection	12333269
48640449	48640472	3	+	28162770	OCIAML3	viability	AGGCAGCTGGCACAGCACGGTGG	CELSR3	ENSG00000008300	0.1932630356901086	[30]	[106]	1	hSpCas9	negative selection	12333270
48639900	48639923	3	-	28162770	OCIAML3	viability	GCAGCTGCTCAGAGCTAGGGAGG	CELSR3	ENSG00000008300	0.48691235505940433	[12]	[54]	4	hSpCas9	negative selection	12333271
48662462	48662485	3	-	28162770	OCIAML3	viability	GGGCCAAGGGCGCATATCGGTGG	CELSR3	ENSG00000008300	-0.3138997211314277	[34]	[84]	-2	hSpCas9	negative selection	12333272
48662060	48662083	3	-	28162770	OCIAML3	viability	GTGTCCTCCCAGCGGAACGCTGG	CELSR3	ENSG00000008300	0.7644463305883131	[116]	[599]	7	hSpCas9	negative selection	12333273
48661767	48661790	3	+	28162770	OCIAML3	viability	GCTGCGGGAGGAAGCGGCAGCGG	CELSR3	ENSG00000008300	-3.915935735211526	[4]	[0]	-9	hSpCas9	negative selection	12333274