Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8837
• Symbol:CFLAR
• Description:CASP8 and FADD like apoptosis regulator

DataSource: http://genomecrispr.dkfz.de/#!/results/CFLAR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
201133093	201133116	2	+	26472758	Jiyoye	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.7917107923873731	[238]	[311]	5	hSpCas9	negative selection	30694
201160742	201160765	2	+	26472758	Jiyoye	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.7896450183282865	[111]	[145]	5	hSpCas9	negative selection	30695
201133032	201133055	2	+	26472758	Jiyoye	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	0.7965870731092228	[70]	[92]	5	hSpCas9	negative selection	30696
201133107	201133130	2	+	26472758	Jiyoye	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.6359940720017542	[63]	[74]	4	hSpCas9	negative selection	30697
201135983	201136006	2	-	26472758	Jiyoye	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	1.4071753815058736	[102]	[205]	8	hSpCas9	negative selection	30698
201136061	201136084	2	-	26472758	Jiyoye	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	0.4473034942111831	[389]	[400]	3	hSpCas9	negative selection	30699
201160563	201160586	2	+	26472758	Jiyoye	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	0.5193848850918985	[135]	[146]	4	hSpCas9	negative selection	30700
201160606	201160629	2	+	26472758	Jiyoye	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	1.7405991152310654	[49]	[125]	8	hSpCas9	negative selection	30701
201133093	201133116	2	+	26472758	KBM7	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.06003287758067355	[935,627]	[434,325]	0	hSpCas9	negative selection	221812
201160742	201160765	2	+	26472758	KBM7	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	-0.420149491011469	[691,380]	[214,155]	-4	hSpCas9	negative selection	221813
201133032	201133055	2	+	26472758	KBM7	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-4.329250312021262	[500,324]	[18,0]	-9	hSpCas9	negative selection	221814
201133107	201133130	2	+	26472758	KBM7	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-2.5648318521514764	[380,280]	[34,17]	-9	hSpCas9	negative selection	221815
201135983	201136006	2	-	26472758	KBM7	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.36071402302738265	[932,757]	[449,558]	4	hSpCas9	negative selection	221816
201136061	201136084	2	-	26472758	KBM7	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-1.978652881711125	[2331,2117]	[398,145]	-8	hSpCas9	negative selection	221817
201160563	201160586	2	+	26472758	KBM7	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-1.2860330008330303	[776,735]	[142,148]	-7	hSpCas9	negative selection	221818
201160606	201160629	2	+	26472758	KBM7	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-2.181860347340261	[335,428]	[71,11]	-8	hSpCas9	negative selection	221819
201133093	201133116	2	+	26472758	Raji	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.8080421255534775	[506]	[205]	7	hSpCas9	negative selection	412930
201160742	201160765	2	+	26472758	Raji	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.04928058081003128	[303]	[72]	0	hSpCas9	negative selection	412931
201133032	201133055	2	+	26472758	Raji	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-2.5248846801259135	[247]	[9]	-9	hSpCas9	negative selection	412932
201133107	201133130	2	+	26472758	Raji	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.5424301096975247	[181]	[28]	-4	hSpCas9	negative selection	412933
201135983	201136006	2	-	26472758	Raji	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.9538131467815893	[306]	[137]	8	hSpCas9	negative selection	412934
201136061	201136084	2	-	26472758	Raji	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-0.631595590230255	[1194]	[178]	-5	hSpCas9	negative selection	412935
201160563	201160586	2	+	26472758	Raji	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	0.12047919298528287	[328]	[82]	1	hSpCas9	negative selection	412936
201160606	201160629	2	+	26472758	Raji	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-0.6581512109893778	[203]	[29]	-5	hSpCas9	negative selection	412937
201133093	201133116	2	+	26472758	K562	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.9376697737128084	[649]	[1050]	7	hSpCas9	negative selection	604048
201160742	201160765	2	+	26472758	K562	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.7963229398083075	[411]	[603]	6	hSpCas9	negative selection	604049
201133032	201133055	2	+	26472758	K562	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-0.07908522214645475	[228]	[182]	0	hSpCas9	negative selection	604050
201133107	201133130	2	+	26472758	K562	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.5042422001321338	[288]	[171]	-3	hSpCas9	negative selection	604051
201135983	201136006	2	-	26472758	K562	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.4849584957131543	[710]	[839]	4	hSpCas9	negative selection	604052
201136061	201136084	2	-	26472758	K562	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	1.076504196613442	[1478]	[2632]	8	hSpCas9	negative selection	604053
201160563	201160586	2	+	26472758	K562	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	0.4938227482912982	[513]	[610]	4	hSpCas9	negative selection	604054
201160606	201160629	2	+	26472758	K562	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	0.6608924590608095	[250]	[334]	5	hSpCas9	negative selection	604055
201133093	201133116	2	+	26627737	DLD1	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-1.4561755947432484	[478]	[103,46,17]	-8	hSpCas9	negative selection	809896
201136228	201136251	2	-	26627737	DLD1	viability	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.005479724694663818	[416]	[112,158,122]	0	hSpCas9	negative selection	809897
201160457	201160480	2	-	26627737	DLD1	viability	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.0065476183490926765	[203]	[60,120,17]	0	hSpCas9	negative selection	809899
201160718	201160741	2	+	26627737	DLD1	viability	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.9730111337806714	[341]	[61,57,44]	-7	hSpCas9	negative selection	809900
201163842	201163865	2	-	26627737	DLD1	viability	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.4368578056432567	[724]	[186,173,144]	-4	hSpCas9	negative selection	809901
201133093	201133116	2	+	26627737	GBM cells	viability after 5 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.04643205024424428	[258]	[142,125]	0	hSpCas9	negative selection	892211
201136228	201136251	2	-	26627737	GBM cells	viability after 5 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.6010734968128786	[238]	[98,69]	-7	hSpCas9	negative selection	892212
201160457	201160480	2	-	26627737	GBM cells	viability after 5 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.09180831152630331	[154]	[72,82]	-1	hSpCas9	negative selection	892214
201160718	201160741	2	+	26627737	GBM cells	viability after 5 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.08401261175537278	[167]	[93,75]	-1	hSpCas9	negative selection	892215
201163842	201163865	2	-	26627737	GBM cells	viability after 5 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.5161236243931584	[563]	[207,214]	-7	hSpCas9	negative selection	892216
201133093	201133116	2	+	26627737	GBM cells	viability after 13 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.7897566006548576	[258]	[104,61]	-7	hSpCas9	negative selection	974526
201136228	201136251	2	-	26627737	GBM cells	viability after 13 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.0224979062012564	[238]	[157,102]	0	hSpCas9	negative selection	974527
201160457	201160480	2	-	26627737	GBM cells	viability after 13 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.4240909166165345	[154]	[135,93]	5	hSpCas9	negative selection	974529
201160718	201160741	2	+	26627737	GBM cells	viability after 13 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.11549454386415253	[167]	[154,52]	1	hSpCas9	negative selection	974530
201163842	201163865	2	-	26627737	GBM cells	viability after 13 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.4451293322328266	[563]	[253,200]	-5	hSpCas9	negative selection	974531
201133093	201133116	2	+	26627737	GBM cells	viability after 21 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-1.8098459069197121	[258]	[36,42]	-8	hSpCas9	negative selection	1056841
201136228	201136251	2	-	26627737	GBM cells	viability after 21 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.48682793175126565	[238]	[88,95]	-4	hSpCas9	negative selection	1056842
201160457	201160480	2	-	26627737	GBM cells	viability after 21 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.5728396779134728	[154]	[130,119]	6	hSpCas9	negative selection	1056844
201160718	201160741	2	+	26627737	GBM cells	viability after 21 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.12357354356359224	[167]	[100,97]	1	hSpCas9	negative selection	1056845
201163842	201163865	2	-	26627737	GBM cells	viability after 21 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.516578221205352	[563]	[244,185]	-4	hSpCas9	negative selection	1056846
201133093	201133116	2	+	26627737	RPE1	viability after 9 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.5345264202698035	[1280]	[275,277]	-4	hSpCas9	negative selection	1139156
201136228	201136251	2	-	26627737	RPE1	viability after 9 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.12430857588462384	[895]	[183,351]	-1	hSpCas9	negative selection	1139157
201160457	201160480	2	-	26627737	RPE1	viability after 9 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.4149256995364231	[314]	[58,224]	3	hSpCas9	negative selection	1139159
201160718	201160741	2	+	26627737	RPE1	viability after 9 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.20420045713441237	[801]	[344,53]	-1	hSpCas9	negative selection	1139160
201163842	201163865	2	-	26627737	RPE1	viability after 9 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.16798409689080884	[1913]	[459,627]	-1	hSpCas9	negative selection	1139161
201133093	201133116	2	+	26627737	RPE1	viability after 12 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.3906912242355513	[1280]	[313,207]	-3	hSpCas9	negative selection	1221471
201136228	201136251	2	-	26627737	RPE1	viability after 12 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.26396740245341843	[895]	[239,340]	1	hSpCas9	negative selection	1221472
201160457	201160480	2	-	26627737	RPE1	viability after 12 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.10016125288778288	[314]	[29,154]	0	hSpCas9	negative selection	1221474
201160718	201160741	2	+	26627737	RPE1	viability after 12 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.6010194506742641	[801]	[177,103]	-4	hSpCas9	negative selection	1221475
201163842	201163865	2	-	26627737	RPE1	viability after 12 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.12379532444113672	[1913]	[333,617]	-1	hSpCas9	negative selection	1221476
201133093	201133116	2	+	26627737	RPE1	viability after 15 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.6461696390817399	[1280]	[200,260]	-4	hSpCas9	negative selection	1303786
201136228	201136251	2	-	26627737	RPE1	viability after 15 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.3311618039578609	[895]	[129,500]	2	hSpCas9	negative selection	1303787
201160457	201160480	2	-	26627737	RPE1	viability after 15 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.6588476954042567	[314]	[45,231]	4	hSpCas9	negative selection	1303789
201160718	201160741	2	+	26627737	RPE1	viability after 15 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.0028505810411938864	[801]	[321,135]	0	hSpCas9	negative selection	1303790
201163842	201163865	2	-	26627737	RPE1	viability after 15 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	0.009935285644218084	[1913]	[394,689]	0	hSpCas9	negative selection	1303791
201133093	201133116	2	+	26627737	RPE1	viability after 18 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.37661396911492034	[1280]	[317,210]	-2	hSpCas9	negative selection	1386101
201136228	201136251	2	-	26627737	RPE1	viability after 18 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.5680568188708881	[895]	[284,436]	3	hSpCas9	negative selection	1386102
201160457	201160480	2	-	26627737	RPE1	viability after 18 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.44022477185341347	[314]	[66,166]	3	hSpCas9	negative selection	1386104
201160718	201160741	2	+	26627737	RPE1	viability after 18 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.18883449881773454	[801]	[200,177]	-1	hSpCas9	negative selection	1386105
201163842	201163865	2	-	26627737	RPE1	viability after 18 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	0.4753617101027656	[1913]	[429,1025]	3	hSpCas9	negative selection	1386106
201133093	201133116	2	+	26627737	HeLa	viability after 8 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.40528095134579867	[609]	[239,154,213]	-4	hSpCas9	negative selection	1468416
201136228	201136251	2	-	26627737	HeLa	viability after 8 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.8943039396532237	[500]	[239,67,73]	-7	hSpCas9	negative selection	1468417
201160457	201160480	2	-	26627737	HeLa	viability after 8 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.12992425804830843	[197]	[138,83,29]	-1	hSpCas9	negative selection	1468419
201160718	201160741	2	+	26627737	HeLa	viability after 8 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.8862747928832893	[292]	[186,239,266]	7	hSpCas9	negative selection	1468420
201163842	201163865	2	-	26627737	HeLa	viability after 8 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.1608349431514221	[853]	[390,299,319]	-1	hSpCas9	negative selection	1468421
201133093	201133116	2	+	26627737	HeLa	viability after 12 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.6728201171576215	[609]	[120,179,169]	-6	hSpCas9	negative selection	1550731
201136228	201136251	2	-	26627737	HeLa	viability after 12 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-1.6349900807105178	[500]	[39,96,58]	-9	hSpCas9	negative selection	1550732
201160457	201160480	2	-	26627737	HeLa	viability after 12 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.40249470553938105	[197]	[9,44,130]	-4	hSpCas9	negative selection	1550734
201160718	201160741	2	+	26627737	HeLa	viability after 12 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.1545946821175594	[292]	[203,90,115]	1	hSpCas9	negative selection	1550735
201163842	201163865	2	-	26627737	HeLa	viability after 12 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.43703604985226463	[853]	[387,116,295]	-4	hSpCas9	negative selection	1550736
201133093	201133116	2	+	26627737	HeLa	viability after 15 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.9195693356927552	[609]	[117,132,143]	-7	hSpCas9	negative selection	1633046
201136228	201136251	2	-	26627737	HeLa	viability after 15 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.9875904473767585	[500]	[119,113,71]	-7	hSpCas9	negative selection	1633047
201160457	201160480	2	-	26627737	HeLa	viability after 15 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.48722726249150483	[197]	[39,59,73]	-4	hSpCas9	negative selection	1633049
201160718	201160741	2	+	26627737	HeLa	viability after 15 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.15134157912014512	[292]	[129,67,204]	1	hSpCas9	negative selection	1633050
201163842	201163865	2	-	26627737	HeLa	viability after 15 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.3341257968301631	[853]	[269,274,282]	-3	hSpCas9	negative selection	1633051
201133093	201133116	2	+	26627737	HeLa	viability after 18 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.9256615522105565	[609]	[78,108,143]	-7	hSpCas9	negative selection	1715361
201136228	201136251	2	-	26627737	HeLa	viability after 18 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.9160753842740592	[500]	[82,103,71]	-7	hSpCas9	negative selection	1715362
201160457	201160480	2	-	26627737	HeLa	viability after 18 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.4313646303497558	[197]	[30,49,73]	-4	hSpCas9	negative selection	1715364
201160718	201160741	2	+	26627737	HeLa	viability after 18 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.15653684333284212	[292]	[89,53,204]	1	hSpCas9	negative selection	1715365
201163842	201163865	2	-	26627737	HeLa	viability after 18 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.3870611087343486	[853]	[167,219,282]	-3	hSpCas9	negative selection	1715366
201133093	201133116	2	+	26627737	HCT116	viability after 6 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.5730465328383775	[740]	[249,130]	3	hSpCas9	negative selection	1797676
201136228	201136251	2	-	26627737	HCT116	viability after 6 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.31637335461237936	[420]	[76,39]	-2	hSpCas9	negative selection	1797677
201160457	201160480	2	-	26627737	HCT116	viability after 6 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.2878574187976697	[204]	[37,19]	-2	hSpCas9	negative selection	1797679
201160718	201160741	2	+	26627737	HCT116	viability after 6 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.7884876532801728	[900]	[52,97]	-4	hSpCas9	negative selection	1797680
201163842	201163865	2	-	26627737	HCT116	viability after 6 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.20806270790063408	[1083]	[191,122]	-1	hSpCas9	negative selection	1797681
201133093	201133116	2	+	26627737	HCT116	viability after 8 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.5202609863191742	[568]	[271,183,200]	-6	hSpCas9	negative selection	1879991
201136228	201136251	2	-	26627737	HCT116	viability after 8 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.473816983287982	[373]	[140,151,151]	-5	hSpCas9	negative selection	1879992
201160457	201160480	2	-	26627737	HCT116	viability after 8 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-1.083616555596527	[223]	[57,81,34]	-8	hSpCas9	negative selection	1879994
201160718	201160741	2	+	26627737	HCT116	viability after 8 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.09142656519680036	[300]	[147,153,226]	1	hSpCas9	negative selection	1879995
201163842	201163865	2	-	26627737	HCT116	viability after 8 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.47436697702666586	[790]	[247,377,313]	-5	hSpCas9	negative selection	1879996
201133093	201133116	2	+	26627737	HCT116	viability after 9 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.7407759652714879	[740]	[252,391]	5	hSpCas9	negative selection	1962306
201136228	201136251	2	-	26627737	HCT116	viability after 9 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.33432691477694665	[420]	[182,14]	-2	hSpCas9	negative selection	1962307
201160457	201160480	2	-	26627737	HCT116	viability after 9 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.3398617283471055	[204]	[99,44]	2	hSpCas9	negative selection	1962309
201160718	201160741	2	+	26627737	HCT116	viability after 9 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.1570110787680462	[900]	[174,247]	-1	hSpCas9	negative selection	1962310
201163842	201163865	2	-	26627737	HCT116	viability after 9 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.6301257687598418	[1083]	[348,58]	-4	hSpCas9	negative selection	1962311
201133093	201133116	2	+	26627737	HCT116	viability after 12 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.3091694539897758	[568]	[291,175,249]	-3	hSpCas9	negative selection	2044621
201136228	201136251	2	-	26627737	HCT116	viability after 12 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.41376938919584605	[373]	[95,223,128]	-4	hSpCas9	negative selection	2044622
201160457	201160480	2	-	26627737	HCT116	viability after 12 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-1.1669882088097832	[223]	[25,68,64]	-8	hSpCas9	negative selection	2044624
201160718	201160741	2	+	26627737	HCT116	viability after 12 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.035304578716561875	[300]	[217,186,76]	0	hSpCas9	negative selection	2044625
201163842	201163865	2	-	26627737	HCT116	viability after 12 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-1.1298774916058392	[790]	[152,226,193]	-8	hSpCas9	negative selection	2044626
201133093	201133116	2	+	26627737	HCT116	viability after 15 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.4139934165731707	[568]	[295,204,240]	-4	hSpCas9	negative selection	2126936
201136228	201136251	2	-	26627737	HCT116	viability after 15 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.05881016007327683	[373]	[252,138,231]	0	hSpCas9	negative selection	2126937
201160457	201160480	2	-	26627737	HCT116	viability after 15 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.7025538076129287	[223]	[53,92,86]	-6	hSpCas9	negative selection	2126939
201160718	201160741	2	+	26627737	HCT116	viability after 15 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.0698924600217165	[300]	[212,126,159]	0	hSpCas9	negative selection	2126940
201163842	201163865	2	-	26627737	HCT116	viability after 15 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.8486305813790974	[790]	[231,243,277]	-7	hSpCas9	negative selection	2126941
201133093	201133116	2	+	26627737	HCT116	viability after 18 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.17074570889766816	[568]	[266,124,353]	-1	hSpCas9	negative selection	2209251
201136228	201136251	2	-	26627737	HCT116	viability after 18 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.3465553259385214	[373]	[106,118,204]	-3	hSpCas9	negative selection	2209252
201160457	201160480	2	-	26627737	HCT116	viability after 18 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-1.4748362924912342	[223]	[26,59,27]	-8	hSpCas9	negative selection	2209254
201160718	201160741	2	+	26627737	HCT116	viability after 18 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.14299005734686265	[300]	[75,114,208]	-1	hSpCas9	negative selection	2209255
201163842	201163865	2	-	26627737	HCT116	viability after 18 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.8680918005091199	[790]	[150,357,104]	-7	hSpCas9	negative selection	2209256
201118411	201118434	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGAAATTGCCTAGGCCCCTGG	CFLAR	ENSG00000003402	1.3244184207716172	[45,19]	[29,3]	5	dCas9-VP64	positive selection	2397499
201118429	201118452	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTAGGACCTCCAATGCCCCAGG	CFLAR	ENSG00000003402	0.8368583077030765	[134,52]	[3,70]	3	dCas9-VP64	positive selection	2397500
201118357	201118380	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAAAAAACTGCACACTATCCGG	CFLAR	ENSG00000003402	-0.4154805473526222	[474,119]	[67,26]	-2	dCas9-VP64	positive selection	2397501
201140107	201140130	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCGCCGGGTGGGCTGGGTGGG	CFLAR	ENSG00000003402	0.29011077495087967	[53,172]	[35,24]	1	dCas9-VP64	positive selection	2411271
201140087	201140110	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGCTGCCACGCTGCAGCCAGG	CFLAR	ENSG00000003402	-0.7289809487978758	[250,72]	[29,10]	-4	dCas9-VP64	positive selection	2411272
201140126	201140149	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGCTGGGGGCGGGGGCTGCGG	CFLAR	ENSG00000003402	2.8938285264002643	[0,0]	[1,0]	8	dCas9-VP64	positive selection	2411273
201132854	201132877	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCCCAGGAAGAGATCTTAAGG	CFLAR	ENSG00000003402	-0.5321840462676235	[115,45]	[9,13]	-3	dCas9-VP64	positive selection	2411342
201132780	201132803	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAAACTGTTAGTTGGCAAAGG	CFLAR	ENSG00000003402	0.9405356894782575	[23,341]	[4,156]	4	dCas9-VP64	positive selection	2411343
201132804	201132827	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTACCATCTCCTATTAAACGGG	CFLAR	ENSG00000003402	-1.2307517299451318	[255,149]	[12,23]	-7	dCas9-VP64	positive selection	2411344
201173225	201173248	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGACGGAGTCTCGCTCTGTGG	CFLAR	ENSG00000003402	-0.9138531946650479	[176,89]	[14,14]	-5	dCas9-VP64	positive selection	2443903
201134532	201134555	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGAGGCAGGAGAATTGCTAG	CFLAR	ENSG00000003402	1.7637175755419017	[20,19]	[24,4]	6	dCas9-VP64	positive selection	2454689
201118411	201118434	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGAAATTGCCTAGGCCCCTGG	CFLAR	ENSG00000003402	-0.1459460449647052	[13,41]	[6,8]	-1	dCas9-VP64	positive selection	2492754
201118429	201118452	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTAGGACCTCCAATGCCCCAGG	CFLAR	ENSG00000003402	0.5202103561508583	[47,125]	[56,24]	4	dCas9-VP64	positive selection	2492755
201118357	201118380	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAAAAAACTGCACACTATCCGG	CFLAR	ENSG00000003402	-0.13626523967323337	[180,100]	[33,49]	-1	dCas9-VP64	positive selection	2492756
201140107	201140130	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCGCCGGGTGGGCTGGGTGGG	CFLAR	ENSG00000003402	-0.07598458364438347	[198,62]	[62,18]	0	dCas9-VP64	positive selection	2506526
201140087	201140110	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGCTGCCACGCTGCAGCCAGG	CFLAR	ENSG00000003402	0.49055135083170454	[89,210]	[36,96]	4	dCas9-VP64	positive selection	2506527
201140126	201140149	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGCTGGGGGCGGGGGCTGCGG	CFLAR	ENSG00000003402	-0.7829928431826723	[46,132]	[9,22]	-7	dCas9-VP64	positive selection	2506528
201132854	201132877	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCCCAGGAAGAGATCTTAAGG	CFLAR	ENSG00000003402	-0.38931676686107236	[119,128]	[36,24]	-4	dCas9-VP64	positive selection	2506597
201132780	201132803	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAAACTGTTAGTTGGCAAAGG	CFLAR	ENSG00000003402	0.053044507798047924	[57,36]	[11,18]	0	dCas9-VP64	positive selection	2506598
201132804	201132827	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTACCATCTCCTATTAAACGGG	CFLAR	ENSG00000003402	-0.25149989726322763	[245,400]	[121,55]	-2	dCas9-VP64	positive selection	2506599
201173225	201173248	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGACGGAGTCTCGCTCTGTGG	CFLAR	ENSG00000003402	1.2938008933610645	[146,100]	[61,133]	7	dCas9-VP64	positive selection	2539158
201134532	201134555	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGAGGCAGGAGAATTGCTAG	CFLAR	ENSG00000003402	-0.8253509621016023	[144,7]	[19,7]	-7	dCas9-VP64	positive selection	2549944
201129965	201129988	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGGTCCCTGACATTAGGTGG	CFLAR	ENSG00000003402	0.137336818062318	[2,2]	[0,4]	3	hSpCas9	positive selection	2978893
201130067	201130090	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCAAACGTATCTTGAAGATGG	CFLAR	ENSG00000003402	-0.26173203069178325	[2,2]	[1,1]	-4	hSpCas9	positive selection	2978894
201130123	201130146	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATAGTCCGAAACAAGGTGAGGG	CFLAR	ENSG00000003402	-0.7707390417288387	[2,2]	[1,0]	-8	hSpCas9	positive selection	2978895
201129982	201130005	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCCCGTAAAATATCCAGAAGG	CFLAR	ENSG00000003402	-1.3845501964609725	[4,3]	[0,0]	-9	hSpCas9	positive selection	2978896
201129965	201129988	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGGTCCCTGACATTAGGTGG	CFLAR	ENSG00000003402	0.04617082562619543	[2,2]	[0,2]	0	hSpCas9	positive selection	3046751
201130067	201130090	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCAAACGTATCTTGAAGATGG	CFLAR	ENSG00000003402	-0.015428505485593158	[2,2]	[2,0]	0	hSpCas9	positive selection	3046752
201130123	201130146	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATAGTCCGAAACAAGGTGAGGG	CFLAR	ENSG00000003402	-0.6002920873450028	[2,2]	[0,0]	-8	hSpCas9	positive selection	3046753
201129982	201130005	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCCCGTAAAATATCCAGAAGG	CFLAR	ENSG00000003402	-0.4819309714360571	[4,4]	[2,1]	-7	hSpCas9	positive selection	3046754
201133107	201133130		+	24336571	A375	resistance to PLX after 7 days	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.10825622544466174	[9,10]	[8,9]	-3	hSpCas9	positive selection	3105235
201136088	201136111		-	24336571	A375	resistance to PLX after 7 days	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.03567417395541783	[126,127]	[117,127]	-1	hSpCas9	positive selection	3105237
201133107	201133130		+	24336571	A375	resistance to PLX after 14 days	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.45798947370596454	[10,11]	[6,6]	4	hSpCas9	positive selection	3163028
201136088	201136111		-	24336571	A375	resistance to PLX after 14 days	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.17862314702822024	[141,129]	[56,54]	-2	hSpCas9	positive selection	3163030
201133107	201133130		+	24336571	A375	viability after 7 days	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.5276013857555713	[6]	[9,10]	7	hSpCas9	negative selection	3220821
201136088	201136111		-	24336571	A375	viability after 7 days	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.6217153204024091	[86]	[126,127]	8	hSpCas9	negative selection	3220823
201133107	201133130		+	24336571	A375	viability after 14 days	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.665117639833372	[6]	[10,11]	8	hSpCas9	negative selection	3278614
201136088	201136111		-	24336571	A375	viability after 14 days	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.7367376298005026	[86]	[141,129]	8	hSpCas9	negative selection	3278616
201133107	201133130	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	3.508287784979054	[147,228]	[26,0]	9	hSpCas9	positive selection	3342875
201136088	201136111	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.3937254797330936	[602,602]	[2,2]	-2	hSpCas9	positive selection	3362105
201135983	201136006	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.8459615969661868	[274,274]	[0,0]	-6	hSpCas9	positive selection	3362106
201129965	201129988	2	-	26780180	HT29	viability (Avana library 4 designs)	AGAAGGTCCCTGACATTAGGTGG	CFLAR	ENSG00000003402	3.11219262304879	[]	[]	8	hSpCas9	negative selection	3415248
201130066	201130089	2	+	26780180	HT29	viability (Avana library 4 designs)	GCTCAAACGTATCTTGAAGATGG	CFLAR	ENSG00000003402	1.54160717906264	[]	[]	6	hSpCas9	negative selection	3415249
201130123	201130146	2	-	26780180	HT29	viability (Avana library 4 designs)	TATAGTCCGAAACAAGGTGAGGG	CFLAR	ENSG00000003402	4.02203464230994	[]	[]	9	hSpCas9	negative selection	3415250
201129982	201130005	2	-	26780180	HT29	viability (Avana library 4 designs)	TTTCCCGTAAAATATCCAGAAGG	CFLAR	ENSG00000003402	1.08151854110546	[]	[]	4	hSpCas9	negative selection	3415251
201129982	201130005	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCCCGTAAAATATCCAGAAGG	CFLAR	ENSG00000003402	-7.59020893897462	[]	[]	-7	hSpCas9	negative selection	3492155
201130123	201130146	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATAGTCCGAAACAAGGTGAGGG	CFLAR	ENSG00000003402	1.66263220651572	[]	[]	2	hSpCas9	negative selection	3492156
201129965	201129988	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGGTCCCTGACATTAGGTGG	CFLAR	ENSG00000003402	3.28377505361802	[]	[]	5	hSpCas9	negative selection	3492157
201130066	201130089	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAAACGTATCTTGAAGATGG	CFLAR	ENSG00000003402	-7.24646082185763	[]	[]	-6	hSpCas9	negative selection	3492158
201130124	201130147	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTATAGTCCGAAACAAGGTGAGG	CFLAR	ENSG00000003402	2.17230198300717	[]	[]	3	hSpCas9	negative selection	3492159
201130081	201130104	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAGATGGACAGAAAAGCTGTGG	CFLAR	ENSG00000003402	-0.570758792005019	[]	[]	0	hSpCas9	negative selection	3492160
201129982	201130005	2	-	26780180	A375	viability (Avana lentiGuide)	TTTCCCGTAAAATATCCAGAAGG	CFLAR	ENSG00000003402	3.33893995378734	[]	[]	3	hSpCas9	negative selection	3600814
201130123	201130146	2	-	26780180	A375	viability (Avana lentiGuide)	TATAGTCCGAAACAAGGTGAGGG	CFLAR	ENSG00000003402	0.486207364213476	[]	[]	0	hSpCas9	negative selection	3600815
201129965	201129988	2	-	26780180	A375	viability (Avana lentiGuide)	AGAAGGTCCCTGACATTAGGTGG	CFLAR	ENSG00000003402	2.47040280310637	[]	[]	2	hSpCas9	negative selection	3600816
201130066	201130089	2	+	26780180	A375	viability (Avana lentiGuide)	GCTCAAACGTATCTTGAAGATGG	CFLAR	ENSG00000003402	-1.90608302889204	[]	[]	-3	hSpCas9	negative selection	3600817
201130124	201130147	2	-	26780180	A375	viability (Avana lentiGuide)	CTATAGTCCGAAACAAGGTGAGG	CFLAR	ENSG00000003402	6.68254899456619	[]	[]	5	hSpCas9	negative selection	3600818
201130081	201130104	2	+	26780180	A375	viability (Avana lentiGuide)	GAAGATGGACAGAAAAGCTGTGG	CFLAR	ENSG00000003402	7.75922980635205	[]	[]	6	hSpCas9	negative selection	3600819
201129982	201130005	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCCCGTAAAATATCCAGAAGG	CFLAR	ENSG00000003402	-0.899448458996803	[6]	[2,3]	-8	hSpCas9	positive selection	3709473
201130123	201130146	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATAGTCCGAAACAAGGTGAGGG	CFLAR	ENSG00000003402	0.059359382292859586	[6]	[6,5]	1	hSpCas9	positive selection	3709474
201129965	201129988	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGGTCCCTGACATTAGGTGG	CFLAR	ENSG00000003402	0.14291118155245863	[4]	[5,4]	4	hSpCas9	positive selection	3709475
201130066	201130089	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAAACGTATCTTGAAGATGG	CFLAR	ENSG00000003402	-0.7787366972471403	[5]	[3,1]	-8	hSpCas9	positive selection	3709476
201130124	201130147	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATAGTCCGAAACAAGGTGAGG	CFLAR	ENSG00000003402	0.2535243212856673	[4]	[5,5]	7	hSpCas9	positive selection	3709477
201130081	201130104	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAGATGGACAGAAAAGCTGTGG	CFLAR	ENSG00000003402	-0.3539694341433064	[4]	[3,3]	-5	hSpCas9	positive selection	3709478
201129982	201130005	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCCCGTAAAATATCCAGAAGG	CFLAR	ENSG00000003402	-0.11349639335169302	[5]	[3,5]	-1	hSpCas9	positive selection	3818080
201130123	201130146	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATAGTCCGAAACAAGGTGAGGG	CFLAR	ENSG00000003402	-0.6794426291356244	[5]	[2,1]	-7	hSpCas9	positive selection	3818081
201129965	201129988	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGGTCCCTGACATTAGGTGG	CFLAR	ENSG00000003402	-0.5122568097553594	[5]	[2,2]	-6	hSpCas9	positive selection	3818082
201130066	201130089	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAAACGTATCTTGAAGATGG	CFLAR	ENSG00000003402	-0.017823609205418728	[4]	[3,4]	0	hSpCas9	positive selection	3818083
201130124	201130147	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATAGTCCGAAACAAGGTGAGG	CFLAR	ENSG00000003402	-0.32880637221728376	[5]	[3,2]	-4	hSpCas9	positive selection	3818084
201130081	201130104	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAGATGGACAGAAAAGCTGTGG	CFLAR	ENSG00000003402	-0.2694767686184811	[5]	[4,2]	-4	hSpCas9	positive selection	3818085
201133107	201133130	2	+	26780180	A375	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.812091168870326	[]	[]	3	hSpCas9	negative selection	3926224
201135983	201136006	2	-	26780180	A375	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.0449406997991679	[]	[]	0	hSpCas9	negative selection	3926225
201136088	201136111	2	-	26780180	A375	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	1.04837499582604	[]	[]	5	hSpCas9	negative selection	3926226
201133107	201133130	2	+	26780180	HT29	viability (GeCKOv2 library)	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	1.20780333234415	[]	[]	6	hSpCas9	negative selection	4034190
201135983	201136006	2	-	26780180	HT29	viability (GeCKOv2 library)	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	1.11253007042577	[]	[]	5	hSpCas9	negative selection	4034191
201136088	201136111	2	-	26780180	HT29	viability (GeCKOv2 library)	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	1.39998094620531	[]	[]	7	hSpCas9	negative selection	4034192
201133107	201133130	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.017996119244656952	[3]	[1,2]	0	hSpCas9	positive selection	4127310
201136088	201136111	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.28185936959749247	[6]	[5,5]	7	hSpCas9	positive selection	4127312
201133107	201133130	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.2709651984330874	[2]	[3,2,0,0]	2	hSpCas9	positive selection	4191332
201136088	201136111	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	1.0826612731403444	[6]	[5,5,7,5]	7	hSpCas9	positive selection	4191334
201133107	201133130	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.24177286189375474	[2]	[2,1]	-5	hSpCas9	positive selection	4262986
201136088	201136111	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.010072018560264573	[4]	[3,2]	0	hSpCas9	positive selection	4327258
201135983	201136006	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.0845867940508814	[3]	[3,1]	1	hSpCas9	positive selection	4327259
201130063	201130085	2	-	27760321	OCIAML3	viability	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	0.1434284634003939	[321,271]	[295,202]	1	hSpCas9	negative selection	4388892
201130129	201130151	2	-	27760321	OCIAML3	viability	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-0.3258923606263071	[49,42]	[11,50]	-3	hSpCas9	negative selection	4388893
201133108	201133130	2	+	27760321	OCIAML3	viability	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.5350690166481238	[241,157]	[82,136]	-5	hSpCas9	negative selection	4388894
201135983	201136005	2	-	27760321	OCIAML3	viability	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.4446764298274615	[119,112]	[66,66]	-4	hSpCas9	negative selection	4388895
201136011	201136033	2	+	27760321	OCIAML3	viability	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.21216260387482205	[600,569]	[360,440]	-2	hSpCas9	negative selection	4388896
201160480	201160502	2	+	27760321	OCIAML3	viability	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	-0.12575962233465254	[362,303]	[274,189]	-1	hSpCas9	negative selection	4388897
201160528	201160550	2	-	27760321	OCIAML3	viability	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.26772660251414615	[688,542]	[384,413]	-3	hSpCas9	negative selection	4388898
201130063	201130085	2	-	27760321	OCIAML2	viability	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.3730405589448823	[321,271]	[123,264]	-4	hSpCas9	negative selection	4472355
201130129	201130151	2	-	27760321	OCIAML2	viability	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	0.03353807266800324	[49,42]	[43,30]	0	hSpCas9	negative selection	4472356
201133108	201133130	2	+	27760321	OCIAML2	viability	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.12108102873791582	[241,157]	[141,214]	1	hSpCas9	negative selection	4472357
201135983	201136005	2	-	27760321	OCIAML2	viability	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.0093230284553667	[119,112]	[72,120]	0	hSpCas9	negative selection	4472358
201136011	201136033	2	+	27760321	OCIAML2	viability	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.49895194186073283	[600,569]	[319,355]	-5	hSpCas9	negative selection	4472359
201160480	201160502	2	+	27760321	OCIAML2	viability	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	0.8340176136824947	[362,303]	[412,565]	9	hSpCas9	negative selection	4472360
201160528	201160550	2	-	27760321	OCIAML2	viability	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.6701802950177741	[688,542]	[248,392]	-6	hSpCas9	negative selection	4472361
201130063	201130085	2	-	27760321	MV411	viability	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.32916047682160543	[321,271]	[206,77]	-2	hSpCas9	negative selection	4555818
201130129	201130151	2	-	27760321	MV411	viability	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	1.2630552022103354	[49,42]	[112,13]	8	hSpCas9	negative selection	4555819
201133108	201133130	2	+	27760321	MV411	viability	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.583180764175869	[241,157]	[154,254]	4	hSpCas9	negative selection	4555820
201135983	201136005	2	-	27760321	MV411	viability	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.2302382153662625	[119,112]	[27,39]	-7	hSpCas9	negative selection	4555821
201136011	201136033	2	+	27760321	MV411	viability	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.04811282559387686	[600,569]	[270,528]	0	hSpCas9	negative selection	4555822
201160480	201160502	2	+	27760321	MV411	viability	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	-0.2644347323755112	[362,303]	[50,379]	-2	hSpCas9	negative selection	4555823
201160528	201160550	2	-	27760321	MV411	viability	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	0.2610224852518963	[688,542]	[218,881]	1	hSpCas9	negative selection	4555824
201130063	201130085	2	-	27760321	HL60	viability	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.6322165686405601	[321,271]	[220,86]	-6	hSpCas9	negative selection	4639281
201130129	201130151	2	-	27760321	HL60	viability	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-1.2181099123605246	[49,42]	[8,23]	-8	hSpCas9	negative selection	4639282
201133108	201133130	2	+	27760321	HL60	viability	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.8399212065679742	[241,157]	[89,89]	-7	hSpCas9	negative selection	4639283
201135983	201136005	2	-	27760321	HL60	viability	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.4853062936685433	[119,112]	[193,68]	6	hSpCas9	negative selection	4639284
201136011	201136033	2	+	27760321	HL60	viability	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.7249508329250649	[600,569]	[295,282]	-6	hSpCas9	negative selection	4639285
201160480	201160502	2	+	27760321	HL60	viability	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	0.13502101834695812	[362,303]	[329,263]	1	hSpCas9	negative selection	4639286
201160528	201160550	2	-	27760321	HL60	viability	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-1.0188982245270068	[688,542]	[220,273]	-7	hSpCas9	negative selection	4639287
201130063	201130085	2	-	27760321	HT1080	viability	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.8207597518890277	[271,211]	[13,98]	-3	hSpCas9	negative selection	4722744
201130129	201130151	2	-	27760321	HT1080	viability	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	2.211736309272715	[42,33]	[125,10]	9	hSpCas9	negative selection	4722745
201133108	201133130	2	+	27760321	HT1080	viability	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-1.3396066874641817	[157,123]	[36,5]	-5	hSpCas9	negative selection	4722746
201135983	201136005	2	-	27760321	HT1080	viability	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.9449147566504308	[112,87]	[26,13]	-4	hSpCas9	negative selection	4722747
201136011	201136033	2	+	27760321	HT1080	viability	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-2.1043506893788435	[569,444]	[78,11]	-6	hSpCas9	negative selection	4722748
201160480	201160502	2	+	27760321	HT1080	viability	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	-0.563812214925886	[303,236]	[17,132]	-3	hSpCas9	negative selection	4722749
201160528	201160550	2	-	27760321	HT1080	viability	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	0.2750402286732258	[542,423]	[202,265]	1	hSpCas9	negative selection	4722750
201130063	201130085	2	-	27760321	HT29	viability after 7 days	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	0.2253110935778863	[271,211]	[460,296,346]	3	hSpCas9	negative selection	4806207
201130129	201130151	2	-	27760321	HT29	viability after 7 days	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-0.16209882791858732	[42,33]	[28,6,92]	-2	hSpCas9	negative selection	4806208
201133108	201133130	2	+	27760321	HT29	viability after 7 days	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.9285832682018407	[157,123]	[330,419,283]	9	hSpCas9	negative selection	4806209
201135983	201136005	2	-	27760321	HT29	viability after 7 days	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.22939653402516558	[112,87]	[137,281,35]	3	hSpCas9	negative selection	4806210
201136011	201136033	2	+	27760321	HT29	viability after 7 days	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	0.06953547248977465	[569,444]	[648,710,687]	1	hSpCas9	negative selection	4806211
201160480	201160502	2	+	27760321	HT29	viability after 7 days	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	-0.4475984380089297	[303,236]	[287,310,172]	-6	hSpCas9	negative selection	4806212
201160528	201160550	2	-	27760321	HT29	viability after 7 days	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	0.1454678874156436	[542,423]	[700,555,802]	2	hSpCas9	negative selection	4806213
201130063	201130085	2	-	27760321	HT29	viability after 25 days	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.6565937393396191	[271,211]	[166,231,121]	-5	hSpCas9	negative selection	4889670
201130129	201130151	2	-	27760321	HT29	viability after 25 days	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-0.9857939194879366	[42,33]	[0,18,50]	-6	hSpCas9	negative selection	4889671
201133108	201133130	2	+	27760321	HT29	viability after 25 days	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.3122879823686582	[157,123]	[186,204,209]	3	hSpCas9	negative selection	4889672
201135983	201136005	2	-	27760321	HT29	viability after 25 days	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.3237470791558714	[112,87]	[38,9,93]	-7	hSpCas9	negative selection	4889673
201136011	201136033	2	+	27760321	HT29	viability after 25 days	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-1.2965918835977996	[569,444]	[241,225,239]	-7	hSpCas9	negative selection	4889674
201160480	201160502	2	+	27760321	HT29	viability after 25 days	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	-0.32319949457253433	[303,236]	[214,270,257]	-3	hSpCas9	negative selection	4889675
201160528	201160550	2	-	27760321	HT29	viability after 25 days	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.4221578048321559	[542,423]	[413,387,436]	-4	hSpCas9	negative selection	4889676
201130063	201130085	2	-	27760321	HT29	viability after 22 days	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.5150749061995581	[271,211]	[150,288,147]	-5	hSpCas9	negative selection	4973133
201130129	201130151	2	-	27760321	HT29	viability after 22 days	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-0.10359477473331147	[42,33]	[0,26,97]	-1	hSpCas9	negative selection	4973134
201133108	201133130	2	+	27760321	HT29	viability after 22 days	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.44319049273516753	[157,123]	[168,223,273]	5	hSpCas9	negative selection	4973135
201135983	201136005	2	-	27760321	HT29	viability after 22 days	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.9523193660006115	[112,87]	[59,70,48]	-6	hSpCas9	negative selection	4973136
201136011	201136033	2	+	27760321	HT29	viability after 22 days	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.8982663280934386	[569,444]	[327,299,315]	-6	hSpCas9	negative selection	4973137
201160480	201160502	2	+	27760321	HT29	viability after 22 days	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	0.0406587481032456	[303,236]	[394,338,227]	0	hSpCas9	negative selection	4973138
201160528	201160550	2	-	27760321	HT29	viability after 22 days	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.28319688582199803	[542,423]	[457,464,454]	-3	hSpCas9	negative selection	4973139
201130063	201130085	2	-	27760321	HT29	viability after 19 days	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.994148346335658	[271,211]	[155,136,125]	-6	hSpCas9	negative selection	5056596
201130129	201130151	2	-	27760321	HT29	viability after 19 days	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-1.083741908264507	[42,33]	[0,3,53]	-6	hSpCas9	negative selection	5056597
201133108	201133130	2	+	27760321	HT29	viability after 19 days	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.0283101775582284	[157,123]	[227,212,62]	0	hSpCas9	negative selection	5056598
201135983	201136005	2	-	27760321	HT29	viability after 19 days	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-2.4269626582571044	[112,87]	[23,8,30]	-8	hSpCas9	negative selection	5056599
201136011	201136033	2	+	27760321	HT29	viability after 19 days	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	0.0461858237647359	[569,444]	[528,469,783]	0	hSpCas9	negative selection	5056600
201160480	201160502	2	+	27760321	HT29	viability after 19 days	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	0.35867309536032127	[303,236]	[306,387,481]	3	hSpCas9	negative selection	5056601
201160528	201160550	2	-	27760321	HT29	viability after 19 days	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.38625069282713553	[542,423]	[731,297,276]	-4	hSpCas9	negative selection	5056602
201130063	201130085	2	-	27760321	HT29	viability after 16 days	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	0.028232962078377777	[271,211]	[99,373,334]	0	hSpCas9	negative selection	5140059
201130129	201130151	2	-	27760321	HT29	viability after 16 days	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-1.2544959635502018	[42,33]	[1,5,44]	-7	hSpCas9	negative selection	5140060
201133108	201133130	2	+	27760321	HT29	viability after 16 days	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.7313777905629956	[157,123]	[174,480,115]	8	hSpCas9	negative selection	5140061
201135983	201136005	2	-	27760321	HT29	viability after 16 days	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.3127939641987878	[112,87]	[38,89,4]	-7	hSpCas9	negative selection	5140062
201136011	201136033	2	+	27760321	HT29	viability after 16 days	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.42409304082186094	[569,444]	[523,423,330]	-4	hSpCas9	negative selection	5140063
201160480	201160502	2	+	27760321	HT29	viability after 16 days	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	0.26797385191475975	[303,236]	[162,481,425]	3	hSpCas9	negative selection	5140064
201160528	201160550	2	-	27760321	HT29	viability after 16 days	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.35811921971401917	[542,423]	[513,450,308]	-4	hSpCas9	negative selection	5140065
201130063	201130085	2	-	27760321	HT29	viability after 13 days	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.15011219120947128	[271,211]	[257,300,202]	-2	hSpCas9	negative selection	5223522
201130129	201130151	2	-	27760321	HT29	viability after 13 days	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-0.5303004966827269	[42,33]	[44,2,43]	-5	hSpCas9	negative selection	5223523
201133108	201133130	2	+	27760321	HT29	viability after 13 days	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.49712578855843037	[157,123]	[168,344,181]	6	hSpCas9	negative selection	5223524
201135983	201136005	2	-	27760321	HT29	viability after 13 days	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.4592134305522	[112,87]	[101,78,73]	-5	hSpCas9	negative selection	5223525
201136011	201136033	2	+	27760321	HT29	viability after 13 days	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.6676479692512995	[569,444]	[279,442,387]	-6	hSpCas9	negative selection	5223526
201160480	201160502	2	+	27760321	HT29	viability after 13 days	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	0.2524857339204957	[303,236]	[204,325,577]	3	hSpCas9	negative selection	5223527
201160528	201160550	2	-	27760321	HT29	viability after 13 days	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.22274450051641578	[542,423]	[552,428,460]	-3	hSpCas9	negative selection	5223528
201130063	201130085	2	-	27760321	HT29	viability after 10 days	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	-0.06743972651433217	[271,211]	[237,231,390]	-1	hSpCas9	negative selection	5306985
201130129	201130151	2	-	27760321	HT29	viability after 10 days	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	0.2872556395097794	[42,33]	[81,25,66]	4	hSpCas9	negative selection	5306986
201133108	201133130	2	+	27760321	HT29	viability after 10 days	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.48762733603573594	[157,123]	[280,256,203]	6	hSpCas9	negative selection	5306987
201135983	201136005	2	-	27760321	HT29	viability after 10 days	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.3516477621532432	[112,87]	[78,167,50]	-4	hSpCas9	negative selection	5306988
201136011	201136033	2	+	27760321	HT29	viability after 10 days	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.81348690387877	[569,444]	[336,298,441]	-7	hSpCas9	negative selection	5306989
201160480	201160502	2	+	27760321	HT29	viability after 10 days	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	0.5584100716819287	[303,236]	[624,381,481]	7	hSpCas9	negative selection	5306990
201160528	201160550	2	-	27760321	HT29	viability after 10 days	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	-0.2147754687141289	[542,423]	[611,328,611]	-3	hSpCas9	negative selection	5306991
201130063	201130085	2	-	27760321	MOLM13	viability	CTTCAAGATACGTTTGAGCAGG	CFLAR	ENSG00000003402	0.033339566922789055	[321,271]	[165,174]	0	hSpCas9	negative selection	5390448
201130129	201130151	2	-	27760321	MOLM13	viability	TTACCTATAGTCCGAAACAAGG	CFLAR	ENSG00000003402	-4.709241394730899	[49,42]	[0,0]	-9	hSpCas9	negative selection	5390449
201133108	201133130	2	+	27760321	MOLM13	viability	GGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.40390988724276333	[241,157]	[102,67]	-3	hSpCas9	negative selection	5390450
201135983	201136005	2	-	27760321	MOLM13	viability	TTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.33184465124858153	[119,112]	[98,68]	2	hSpCas9	negative selection	5390451
201136011	201136033	2	+	27760321	MOLM13	viability	CTGGTTGCCCCAGATCAACTGG	CFLAR	ENSG00000003402	-0.2722481227256036	[600,569]	[302,248]	-2	hSpCas9	negative selection	5390452
201160480	201160502	2	+	27760321	MOLM13	viability	TCTTGCATCTCAGTATGCATGG	CFLAR	ENSG00000003402	1.1411735231308815	[362,303]	[569,279]	7	hSpCas9	negative selection	5390453
201160528	201160550	2	-	27760321	MOLM13	viability	TCTCGGTGCTCGGGCATACAGG	CFLAR	ENSG00000003402	0.7622806050226776	[688,542]	[266,856]	5	hSpCas9	negative selection	5390454
201116224	201116247	2	+	27661255	K562	viability	GGACTCCCGGAGCTAGGGGTGGG	CFLAR	ENSG00000003402	-2.0708818655689543	[256,359]	[60,55]	-9	dCas9-KRAB	negative selection	5470523
201118683	201118706	2	+	27661255	K562	viability	GGCGGGGATTAGGCGTGAAGCGG	CFLAR	ENSG00000003402	-0.0579117384632247	[743,604]	[586,461]	-2	dCas9-KRAB	negative selection	5470524
201118705	201118728	2	+	27661255	K562	viability	GTTCAGCAGGCAGAGGTTCTCGG	CFLAR	ENSG00000003402	0.39509685993737925	[521,762]	[712,633]	9	dCas9-KRAB	negative selection	5470525
201118857	201118880	2	+	27661255	K562	viability	GGTCCCGGCGGAGATCCAGTGGG	CFLAR	ENSG00000003402	-0.16269914919169545	[837,833]	[594,597]	-5	dCas9-KRAB	negative selection	5470526
201119089	201119112	2	+	27661255	K562	viability	GGAATGGACTCTGGGGAATGGGG	CFLAR	ENSG00000003402	0.17609737142528548	[1346,1375]	[1352,1121]	6	dCas9-KRAB	negative selection	5470527
201118735	201118758	2	-	27661255	K562	viability	GCATCAACAGGTGGCTTCGCCGG	CFLAR	ENSG00000003402	0.16720402968799897	[344,347]	[347,278]	6	dCas9-KRAB	negative selection	5470528
201133107	201133130	2	+	27260156	BXPC3	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.6992064210518809	[427]	[174,317,293,328]	-8	hSpCas9	negative selection	5535446
201136088	201136111	2	-	27260156	BXPC3	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.08107579720735147	[1256]	[1198,1382,1433,1580]	1	hSpCas9	negative selection	5599718
201135983	201136006	2	-	27260156	BXPC3	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.315242139923973	[640]	[281,260,264,265]	-9	hSpCas9	negative selection	5599719
201133107	201133130	2	+	27260156	A673	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.24984723687800311	[427]	[752,618,542,540]	6	hSpCas9	negative selection	5656697
201136088	201136111	2	-	27260156	A673	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.037223083819419855	[1256]	[1724,1335,1326,1529]	-1	hSpCas9	negative selection	5720969
201135983	201136006	2	-	27260156	A673	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.2824666462921435	[640]	[1007,750,995,1003]	6	hSpCas9	negative selection	5720970
201133107	201133130	2	+	27260156	A375	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.48254975842861697	[427]	[842,892,511,584]	7	hSpCas9	negative selection	5777948
201136088	201136111	2	-	27260156	A375	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.5262151417112408	[1256]	[1781,2291,2601,1829]	7	hSpCas9	negative selection	5842220
201135983	201136006	2	-	27260156	A375	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.30223183319331665	[640]	[947,1170,896,730]	4	hSpCas9	negative selection	5842221
201133107	201133130	2	+	27260156	COLO741	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.3687979120324486	[427]	[658,845,614]	7	hSpCas9	negative selection	5899199
201136088	201136111	2	-	27260156	COLO741	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.09453602365580394	[1256]	[2083,1466,1626]	2	hSpCas9	negative selection	5963471
201135983	201136006	2	-	27260156	COLO741	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.33980317141147526	[640]	[1111,985,1016]	7	hSpCas9	negative selection	5963472
201133107	201133130	2	+	27260156	CAL120	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.8524289108437306	[427]	[192,354,320]	-8	hSpCas9	negative selection	6020450
201136088	201136111	2	-	27260156	CAL120	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.17349639632603897	[1256]	[1786,1913,1596]	2	hSpCas9	negative selection	6084722
201135983	201136006	2	-	27260156	CAL120	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.783147386418902	[640]	[555,369,477]	-8	hSpCas9	negative selection	6084723
201133107	201133130	2	+	27260156	CADOES1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.23366698516175155	[427]	[464,447,469,489]	4	hSpCas9	negative selection	6141701
201136088	201136111	2	-	27260156	CADOES1	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.40973262549918066	[1256]	[1502,1499,1406,1811]	6	hSpCas9	negative selection	6205973
201135983	201136006	2	-	27260156	CADOES1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.21544788644963525	[640]	[633,816,604,713]	3	hSpCas9	negative selection	6205974
201133107	201133130	2	+	27260156	EWS502	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.22270302582685098	[427]	[447,574,609,486]	4	hSpCas9	negative selection	6262952
201136088	201136111	2	-	27260156	EWS502	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.26123051357220417	[1256]	[1427,1217,1733,2067]	4	hSpCas9	negative selection	6327224
201135983	201136006	2	-	27260156	EWS502	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.23633642193622523	[640]	[654,876,727,960]	4	hSpCas9	negative selection	6327225
201133107	201133130	2	+	27260156	EW8	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.09705025680393578	[427]	[462,354,198,315]	-2	hSpCas9	negative selection	6384203
201136088	201136111	2	-	27260156	EW8	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.24171265301898326	[1256]	[1664,1263,837,1160]	4	hSpCas9	negative selection	6448475
201135983	201136006	2	-	27260156	EW8	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.21547140747520815	[640]	[390,552,343,511]	-4	hSpCas9	negative selection	6448476
201133107	201133130	2	+	27260156	CORL105	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.004156674864091214	[427]	[597,375,530,514]	0	hSpCas9	negative selection	6505454
201136088	201136111	2	-	27260156	CORL105	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.2739403792338859	[1256]	[1791,1558,2364,1497]	5	hSpCas9	negative selection	6569726
201135983	201136006	2	-	27260156	CORL105	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.8525693009537824	[640]	[337,463,412,442]	-9	hSpCas9	negative selection	6569727
201133107	201133130	2	+	27260156	HS294T	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.8405138627108752	[427]	[80,40,118,138]	-8	hSpCas9	negative selection	6626705
201136088	201136111	2	-	27260156	HS294T	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.3132050562903097	[1256]	[491,502,402,1114]	4	hSpCas9	negative selection	6690977
201135983	201136006	2	-	27260156	HS294T	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.4930733249035095	[640]	[78,61,102,113]	-9	hSpCas9	negative selection	6690978
201133107	201133130	2	+	27260156	HCC44	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.6826245027596689	[427]	[473,252,281,216]	-7	hSpCas9	negative selection	6747956
201136088	201136111	2	-	27260156	HCC44	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.42418202615622524	[1256]	[1803,1643,2436,1850]	7	hSpCas9	negative selection	6812228
201135983	201136006	2	-	27260156	HCC44	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.0801661071017834	[640]	[376,218,432,374]	-8	hSpCas9	negative selection	6812229
201133107	201133130	2	+	27260156	G402	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.2544243568144086	[427]	[518,791,883,304]	3	hSpCas9	negative selection	6869207
201136088	201136111	2	-	27260156	G402	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.5612713801255644	[1256]	[2491,2986,2220,1458]	7	hSpCas9	negative selection	6933479
201135983	201136006	2	-	27260156	G402	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.2863338021643301	[640]	[887,1262,668,997]	3	hSpCas9	negative selection	6933480
201133107	201133130	2	+	27260156	L33	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.2951922898947116	[427]	[391,120,222,351]	-6	hSpCas9	negative selection	6990458
201136088	201136111	2	-	27260156	L33	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.09939923664387962	[1256]	[1228,478,672,1221]	-2	hSpCas9	negative selection	7054730
201135983	201136006	2	-	27260156	L33	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.35414023655248095	[640]	[581,193,310,453]	-7	hSpCas9	negative selection	7054731
201133107	201133130	2	+	27260156	K562	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.7049504311580139	[427]	[506,981,754,279]	8	hSpCas9	negative selection	7111709
201136088	201136111	2	-	27260156	K562	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.16462993353078303	[1256]	[913,1443,1552,1086]	2	hSpCas9	negative selection	7175981
201135983	201136006	2	-	27260156	K562	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.46979480089617004	[640]	[1058,756,824,554]	6	hSpCas9	negative selection	7175982
201133107	201133130	2	+	27260156	HT29	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.6139780512444948	[427]	[417,460,318,193]	-7	hSpCas9	negative selection	7232960
201136088	201136111	2	-	27260156	HT29	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.09231614084852713	[1256]	[1636,1756,1674,1466]	1	hSpCas9	negative selection	7297232
201135983	201136006	2	-	27260156	HT29	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.9316068191114908	[640]	[389,335,466,427]	-8	hSpCas9	negative selection	7297233
201133107	201133130	2	+	27260156	MHHES1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.3136495529232842	[427]	[589,628,610,562]	6	hSpCas9	negative selection	7354211
201136088	201136111	2	-	27260156	MHHES1	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.23626774355094327	[1256]	[1960,1762,1797,1253]	4	hSpCas9	negative selection	7418483
201135983	201136006	2	-	27260156	MHHES1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.19381043171421491	[640]	[830,1008,637,823]	3	hSpCas9	negative selection	7418484
201133107	201133130	2	+	27260156	MEWO	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.24753302006271583	[427]	[485,487,453]	5	hSpCas9	negative selection	7475462
201136088	201136111	2	-	27260156	MEWO	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.036013729345911516	[1256]	[1366,1021,1094]	-1	hSpCas9	negative selection	7539734
201135983	201136006	2	-	27260156	MEWO	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.2655633723655027	[640]	[856,699,631]	6	hSpCas9	negative selection	7539735
201133107	201133130	2	+	27260156	LNCAPCLONEFGC	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.3289806268542048	[427]	[391,381,604,594]	5	hSpCas9	negative selection	7596713
201136088	201136111	2	-	27260156	LNCAPCLONEFGC	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.24717619719368655	[1256]	[1073,1468,1320,1533]	4	hSpCas9	negative selection	7660985
201135983	201136006	2	-	27260156	LNCAPCLONEFGC	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.22751545068411533	[640]	[690,601,707,726]	3	hSpCas9	negative selection	7660986
201133107	201133130	2	+	27260156	PANC0327	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.7477597514636323	[427]	[187,338,235,124]	-7	hSpCas9	negative selection	7717964
201136088	201136111	2	-	27260156	PANC0327	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.24179846438131025	[1256]	[1152,859,953,837]	-4	hSpCas9	negative selection	7782236
201135983	201136006	2	-	27260156	PANC0327	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-2.2900220941693963	[640]	[92,184,141,34]	-9	hSpCas9	negative selection	7782237
201133107	201133130	2	+	27260156	NCIH2009	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.6716381559928617	[427]	[572,355,235]	-7	hSpCas9	negative selection	7839215
201136088	201136111	2	-	27260156	NCIH2009	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.2239266123092145	[1256]	[2495,1873,1870]	3	hSpCas9	negative selection	7903487
201135983	201136006	2	-	27260156	NCIH2009	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.9278055579951586	[640]	[539,480,403]	-8	hSpCas9	negative selection	7903488
201133107	201133130	2	+	27260156	NCIH1373	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-1.3682427585017765	[427]	[278,186,133,40]	-8	hSpCas9	negative selection	7960466
201136088	201136111	2	-	27260156	NCIH1373	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.6204435784798918	[1256]	[2557,2046,2208,497]	6	hSpCas9	negative selection	8024738
201135983	201136006	2	-	27260156	NCIH1373	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.6895529136211467	[640]	[160,218,295,52]	-9	hSpCas9	negative selection	8024739
201133107	201133130	2	+	27260156	PATU8902	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-1.6858192533814313	[427]	[54,162,291,205]	-8	hSpCas9	negative selection	8081717
201136088	201136111	2	-	27260156	PATU8902	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.8049617915276936	[1256]	[2276,4394,2703,2923]	8	hSpCas9	negative selection	8145989
201135983	201136006	2	-	27260156	PATU8902	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-2.4019899031068985	[640]	[250,236,28,195]	-9	hSpCas9	negative selection	8145990
201133107	201133130	2	+	27260156	PANC1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.22250743797664713	[427]	[417,256,294,276]	-4	hSpCas9	negative selection	8202968
201136088	201136111	2	-	27260156	PANC1	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.21988079458654242	[1256]	[981,1814,1439,945]	3	hSpCas9	negative selection	8267240
201135983	201136006	2	-	27260156	PANC1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.2835876996959451	[640]	[372,437,503,480]	-4	hSpCas9	negative selection	8267241
201133107	201133130	2	+	27260156	PANC0813	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.8594576813539012	[427]	[172,309,242,366]	-8	hSpCas9	negative selection	8324219
201136088	201136111	2	-	27260156	PANC0813	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.16799844227886318	[1256]	[1546,2177,1458,1448]	2	hSpCas9	negative selection	8388491
201135983	201136006	2	-	27260156	PANC0813	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-1.7085609742328778	[640]	[318,187,274,151]	-9	hSpCas9	negative selection	8388492
201133107	201133130	2	+	27260156	RDES	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.20477099574234137	[427]	[348,419,411,549]	-3	hSpCas9	negative selection	8445470
201136088	201136111	2	-	27260156	RDES	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.20295597073488736	[1256]	[1354,1396,1970,2045]	3	hSpCas9	negative selection	8509742
201135983	201136006	2	-	27260156	RDES	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.10399121013429652	[640]	[566,621,697,900]	-2	hSpCas9	negative selection	8509743
201133107	201133130	2	+	27260156	PC3	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.168539249703289	[427]	[296,663,625,405]	4	hSpCas9	negative selection	8566721
201136088	201136111	2	-	27260156	PC3	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.0603879797481619	[1256]	[729,1490,2245,1247]	1	hSpCas9	negative selection	8630993
201135983	201136006	2	-	27260156	PC3	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.13766488484118694	[640]	[417,512,1256,920]	3	hSpCas9	negative selection	8630994
201133107	201133130	2	+	27260156	PATU8988T	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.0291466596924283	[427]	[479,443,328,369]	0	hSpCas9	negative selection	8687972
201136088	201136111	2	-	27260156	PATU8988T	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.0651464499484824	[1256]	[1160,1316,986,1656]	1	hSpCas9	negative selection	8752244
201135983	201136006	2	-	27260156	PATU8988T	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.49148646384341815	[640]	[465,405,415,473]	-7	hSpCas9	negative selection	8752245
201133107	201133130	2	+	27260156	T47D	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.4509581323966859	[427]	[670,662,694,698]	8	hSpCas9	negative selection	8809223
201136088	201136111	2	-	27260156	T47D	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.0803604855172182	[1256]	[1743,1312,1565,1591]	1	hSpCas9	negative selection	8873495
201135983	201136006	2	-	27260156	T47D	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.22096995864945207	[640]	[788,898,888,901]	5	hSpCas9	negative selection	8873496
201133107	201133130	2	+	27260156	SU8686	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-1.7725404613756708	[427]	[151,117,121,96]	-9	hSpCas9	negative selection	8930474
201136088	201136111	2	-	27260156	SU8686	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.1436974547133798	[1256]	[1031,1070,1598,1977]	2	hSpCas9	negative selection	8994746
201135983	201136006	2	-	27260156	SU8686	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-2.3617455351088834	[640]	[102,83,105,223]	-9	hSpCas9	negative selection	8994747
201133107	201133130	2	+	27260156	SKES1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.31628317210324997	[427]	[709,615,407,434]	6	hSpCas9	negative selection	9051725
201136088	201136111	2	-	27260156	SKES1	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.008021746515199712	[1256]	[1317,1395,1240,1116]	0	hSpCas9	negative selection	9115997
201135983	201136006	2	-	27260156	SKES1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.3469707239452419	[640]	[996,989,708,619]	7	hSpCas9	negative selection	9115998
201133107	201133130	2	+	27260156	TOV112D	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.4667595043192302	[427]	[807,847,464,335]	8	hSpCas9	negative selection	9172976
201136088	201136111	2	-	27260156	TOV112D	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.06917242576007854	[1256]	[941,1673,932,1339]	-1	hSpCas9	negative selection	9237248
201135983	201136006	2	-	27260156	TOV112D	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.20200801371742244	[640]	[671,1027,892,433]	4	hSpCas9	negative selection	9237249
201133107	201133130	2	+	27260156	TC71	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.15188426873951077	[427]	[538,483,498,516]	4	hSpCas9	negative selection	9294227
201136088	201136111	2	-	27260156	TC71	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	-0.03786105335465484	[1256]	[1196,1277,1367,1413]	-1	hSpCas9	negative selection	9358499
201135983	201136006	2	-	27260156	TC71	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.11009345166763268	[640]	[626,888,690,764]	3	hSpCas9	negative selection	9358500
201133107	201133130	2	+	27260156	TC32	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.2978068445908587	[427]	[428,498,550,481]	5	hSpCas9	negative selection	9415478
201136088	201136111	2	-	27260156	TC32	viability	TACCAGACTGCTTGTACTTCTGG	CFLAR	ENSG00000003402	0.11105396243763832	[1256]	[1265,1001,1596,1322]	2	hSpCas9	negative selection	9479750
201135983	201136006	2	-	27260156	TC32	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.47266566491637535	[640]	[797,821,869,812]	7	hSpCas9	negative selection	9479751
201133093	201133116	2	+	27869803	HPAFII	viability after 27 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.9321483580574176	[171]	[117,217,NaN]	7	hSpCas9	negative selection	9572944
201136228	201136251	2	-	27869803	HPAFII	viability after 27 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.8282015614205627	[238]	[155,278,NaN]	6	hSpCas9	negative selection	9572945
201160457	201160480	2	-	27869803	HPAFII	viability after 27 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.7439594638611068	[88]	[97,61,NaN]	6	hSpCas9	negative selection	9572947
201160718	201160741	2	+	27869803	HPAFII	viability after 27 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.02636310319085791	[226]	[246,8,NaN]	0	hSpCas9	negative selection	9572948
201163842	201163865	2	-	27869803	HPAFII	viability after 27 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.8257583271966646	[528]	[43,250,NaN]	-5	hSpCas9	negative selection	9572949
201133093	201133116	2	+	27869803	HPAFII	viability after 15 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.10294876027576094	[171]	[126,242,NaN]	1	hSpCas9	negative selection	9655393
201136228	201136251	2	-	27869803	HPAFII	viability after 15 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.2531314503323687	[238]	[299,162,NaN]	-3	hSpCas9	negative selection	9655394
201160457	201160480	2	-	27869803	HPAFII	viability after 15 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.037072297465475135	[88]	[173,42,NaN]	0	hSpCas9	negative selection	9655396
201160718	201160741	2	+	27869803	HPAFII	viability after 15 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.01771030002981358	[226]	[529,70,NaN]	0	hSpCas9	negative selection	9655397
201163842	201163865	2	-	27869803	HPAFII	viability after 15 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-0.5933672787237411	[528]	[234,464,NaN]	-6	hSpCas9	negative selection	9655398
201133093	201133116	2	+	27869803	ASPC1	viability after 36 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.17552785254083642	[666]	[298,316,191]	1	hSpCas9	negative selection	9737842
201136228	201136251	2	-	27869803	ASPC1	viability after 36 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	-0.5239588014645087	[589]	[228,119,99]	-5	hSpCas9	negative selection	9737843
201160457	201160480	2	-	27869803	ASPC1	viability after 36 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	1.2463125941546565	[304]	[787,63,23]	9	hSpCas9	negative selection	9737845
201160718	201160741	2	+	27869803	ASPC1	viability after 36 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.13748815227784048	[554]	[165,212,243]	1	hSpCas9	negative selection	9737846
201163842	201163865	2	-	27869803	ASPC1	viability after 36 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	0.18709989716178366	[1302]	[581,676,340]	1	hSpCas9	negative selection	9737847
201133093	201133116	2	+	27869803	PATU8988S	viability after 35 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.5901259172470132	[665]	[257,97,NaN]	-5	hSpCas9	negative selection	9820291
201136228	201136251	2	-	27869803	PATU8988S	viability after 35 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.3155769526941561	[416]	[213,203,NaN]	3	hSpCas9	negative selection	9820292
201160457	201160480	2	-	27869803	PATU8988S	viability after 35 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-1.1750661746056297	[198]	[32,37,NaN]	-8	hSpCas9	negative selection	9820294
201160718	201160741	2	+	27869803	PATU8988S	viability after 35 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	0.0800281437040939	[537]	[245,211,NaN]	0	hSpCas9	negative selection	9820295
201163842	201163865	2	-	27869803	PATU8988S	viability after 35 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-1.2353517864518913	[1051]	[161,197,NaN]	-8	hSpCas9	negative selection	9820296
201133093	201133116	2	+	27869803	PATU8988S	viability after 31 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.7385475838596529	[665]	[174,138,NaN]	-7	hSpCas9	negative selection	9902740
201136228	201136251	2	-	27869803	PATU8988S	viability after 31 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.6032407739668472	[416]	[223,288,NaN]	7	hSpCas9	negative selection	9902741
201160457	201160480	2	-	27869803	PATU8988S	viability after 31 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	-0.8880068265358072	[198]	[30,57,NaN]	-7	hSpCas9	negative selection	9902743
201160718	201160741	2	+	27869803	PATU8988S	viability after 31 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.10058294755158771	[537]	[185,217,NaN]	-1	hSpCas9	negative selection	9902744
201163842	201163865	2	-	27869803	PATU8988S	viability after 31 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-1.1221660383092928	[1051]	[142,255,NaN]	-8	hSpCas9	negative selection	9902745
201133093	201133116	2	+	27869803	HPAFII	viability after 35 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.6389194140580393	[171]	[17,267,NaN]	4	hSpCas9	negative selection	9985189
201136228	201136251	2	-	27869803	HPAFII	viability after 35 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.6114005869890413	[238]	[110,267,NaN]	4	hSpCas9	negative selection	9985190
201160457	201160480	2	-	27869803	HPAFII	viability after 35 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.3156434745149277	[88]	[88,18,NaN]	2	hSpCas9	negative selection	9985192
201160718	201160741	2	+	27869803	HPAFII	viability after 35 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.8779915296283959	[226]	[62,61,NaN]	-5	hSpCas9	negative selection	9985193
201163842	201163865	2	-	27869803	HPAFII	viability after 35 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-1.356176387998287	[528]	[26,191,NaN]	-6	hSpCas9	negative selection	9985194
201133093	201133116	2	+	27869803	HPAFII	viability after 31 days	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.4435155803483071	[171]	[47,221,NaN]	3	hSpCas9	negative selection	10067638
201136228	201136251	2	-	27869803	HPAFII	viability after 31 days	TTCTAGCCACAAGCTAAAGGAGG	CFLAR	ENSG00000003402	0.37503326042703705	[238]	[116,235,NaN]	2	hSpCas9	negative selection	10067639
201160457	201160480	2	-	27869803	HPAFII	viability after 31 days	ATTTCTGGACTTCATAGCCCAGG	CFLAR	ENSG00000003402	0.6346926448575884	[88]	[100,51,NaN]	4	hSpCas9	negative selection	10067641
201160718	201160741	2	+	27869803	HPAFII	viability after 31 days	TGTGGTGTCAGAGGGCCAGCTGG	CFLAR	ENSG00000003402	-0.4697273463916438	[226]	[102,79,NaN]	-3	hSpCas9	negative selection	10067642
201163842	201163865	2	-	27869803	HPAFII	viability after 31 days	TCAATGTGAAGATCCAGGAGTGG	CFLAR	ENSG00000003402	-1.1544468836763864	[528]	[29,245,NaN]	-6	hSpCas9	negative selection	10067643
201133093	201133116	2	+	28162770	P31FUJ	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.4718375022559993	[342]	[558]	5	hSpCas9	negative selection	10132321
201160742	201160765	2	+	28162770	P31FUJ	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.6259682271437745	[251]	[456]	7	hSpCas9	negative selection	10132322
201133032	201133055	2	+	28162770	P31FUJ	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-0.4703015181410347	[111]	[94]	-4	hSpCas9	negative selection	10132323
201133107	201133130	2	+	28162770	P31FUJ	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.6062605999418229	[113]	[87]	-5	hSpCas9	negative selection	10132324
201135983	201136006	2	-	28162770	P31FUJ	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.18561551896993633	[390]	[403]	-2	hSpCas9	negative selection	10132325
201136061	201136084	2	-	28162770	P31FUJ	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	0.23184574308369754	[1028]	[1419]	2	hSpCas9	negative selection	10132326
201160563	201160586	2	+	28162770	P31FUJ	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	0.31140720279163336	[370]	[540]	3	hSpCas9	negative selection	10132327
201160606	201160629	2	+	28162770	P31FUJ	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	0.314192446107757	[153]	[224]	3	hSpCas9	negative selection	10132328
201133093	201133116	2	+	28162770	TF1	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10301687
201160742	201160765	2	+	28162770	TF1	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10301688
201133032	201133055	2	+	28162770	TF1	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10301689
201133107	201133130	2	+	28162770	TF1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10301690
201135983	201136006	2	-	28162770	TF1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10301691
201136061	201136084	2	-	28162770	TF1	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10301692
201160563	201160586	2	+	28162770	TF1	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10301693
201160606	201160629	2	+	28162770	TF1	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10301694
201133093	201133116	2	+	28162770	SKM1	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.8208417187796506	[113]	[355]	7	hSpCas9	negative selection	10471053
201160742	201160765	2	+	28162770	SKM1	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.4925089253028738	[77]	[193]	5	hSpCas9	negative selection	10471054
201133032	201133055	2	+	28162770	SKM1	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-1.690757164743753	[41]	[22]	-8	hSpCas9	negative selection	10471055
201133107	201133130	2	+	28162770	SKM1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.5153403597879538	[37]	[46]	-4	hSpCas9	negative selection	10471056
201135983	201136006	2	-	28162770	SKM1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.061484293251569344	[115]	[213]	0	hSpCas9	negative selection	10471057
201136061	201136084	2	-	28162770	SKM1	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	0.543647774294675	[207]	[535]	5	hSpCas9	negative selection	10471058
201160563	201160586	2	+	28162770	SKM1	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.3843154597979615	[78]	[106]	-3	hSpCas9	negative selection	10471059
201160606	201160629	2	+	28162770	SKM1	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-0.34666368847534734	[40]	[56]	-3	hSpCas9	negative selection	10471060
201133093	201133116	2	+	28162770	SKM1	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.8208417187796506	[113]	[355]	7	hSpCas9	negative selection	10640419
201160742	201160765	2	+	28162770	SKM1	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.4925089253028738	[77]	[193]	5	hSpCas9	negative selection	10640420
201133032	201133055	2	+	28162770	SKM1	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-1.690757164743753	[41]	[22]	-8	hSpCas9	negative selection	10640421
201133107	201133130	2	+	28162770	SKM1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.5153403597879538	[37]	[46]	-4	hSpCas9	negative selection	10640422
201135983	201136006	2	-	28162770	SKM1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.061484293251569344	[115]	[213]	0	hSpCas9	negative selection	10640423
201136061	201136084	2	-	28162770	SKM1	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	0.543647774294675	[207]	[535]	5	hSpCas9	negative selection	10640424
201160563	201160586	2	+	28162770	SKM1	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.3843154597979615	[78]	[106]	-3	hSpCas9	negative selection	10640425
201160606	201160629	2	+	28162770	SKM1	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-0.34666368847534734	[40]	[56]	-3	hSpCas9	negative selection	10640426
201133093	201133116	2	+	28162770	PL21	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.5595631385571644	[356]	[228]	5	hSpCas9	negative selection	10809785
201160742	201160765	2	+	28162770	PL21	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	-0.05428166103976553	[166]	[69]	0	hSpCas9	negative selection	10809786
201133032	201133055	2	+	28162770	PL21	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-2.7998603855106796	[111]	[6]	-9	hSpCas9	negative selection	10809787
201133107	201133130	2	+	28162770	PL21	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-3.9697853869529927	[143]	[3]	-9	hSpCas9	negative selection	10809788
201135983	201136006	2	-	28162770	PL21	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.027010255645942394	[404]	[172]	0	hSpCas9	negative selection	10809789
201136061	201136084	2	-	28162770	PL21	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-1.166735886452017	[814]	[157]	-7	hSpCas9	negative selection	10809790
201160563	201160586	2	+	28162770	PL21	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-1.5547478876741487	[242]	[35]	-7	hSpCas9	negative selection	10809791
201160606	201160629	2	+	28162770	PL21	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-5.157412390128764	[163]	[1]	-9	hSpCas9	negative selection	10809792
201133093	201133116	2	+	28162770	P31FUJ	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.4718375022559993	[342]	[558]	5	hSpCas9	negative selection	10979151
201160742	201160765	2	+	28162770	P31FUJ	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.6259682271437745	[251]	[456]	7	hSpCas9	negative selection	10979152
201133032	201133055	2	+	28162770	P31FUJ	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-0.4703015181410347	[111]	[94]	-4	hSpCas9	negative selection	10979153
201133107	201133130	2	+	28162770	P31FUJ	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.6062605999418229	[113]	[87]	-5	hSpCas9	negative selection	10979154
201135983	201136006	2	-	28162770	P31FUJ	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.18561551896993633	[390]	[403]	-2	hSpCas9	negative selection	10979155
201136061	201136084	2	-	28162770	P31FUJ	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	0.23184574308369754	[1028]	[1419]	2	hSpCas9	negative selection	10979156
201160563	201160586	2	+	28162770	P31FUJ	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	0.31140720279163336	[370]	[540]	3	hSpCas9	negative selection	10979157
201160606	201160629	2	+	28162770	P31FUJ	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	0.314192446107757	[153]	[224]	3	hSpCas9	negative selection	10979158
201133093	201133116	2	+	28162770	OCIAML5	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.3276394513709007	[146]	[332]	2	hSpCas9	negative selection	11148517
201160742	201160765	2	+	28162770	OCIAML5	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	-0.8606797011687051	[167]	[166]	-5	hSpCas9	negative selection	11148518
201133032	201133055	2	+	28162770	OCIAML5	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-0.6821415694216846	[23]	[26]	-4	hSpCas9	negative selection	11148519
201133107	201133130	2	+	28162770	OCIAML5	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-1.1569211523924179	[62]	[50]	-6	hSpCas9	negative selection	11148520
201135983	201136006	2	-	28162770	OCIAML5	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.10916395168993898	[290]	[486]	-1	hSpCas9	negative selection	11148521
201136061	201136084	2	-	28162770	OCIAML5	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-0.054426803639604726	[446]	[776]	0	hSpCas9	negative selection	11148522
201160563	201160586	2	+	28162770	OCIAML5	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.8889033390443684	[237]	[231]	-5	hSpCas9	negative selection	11148523
201160606	201160629	2	+	28162770	OCIAML5	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	0.6758649848207803	[85]	[247]	6	hSpCas9	negative selection	11148524
201133093	201133116	2	+	28162770	EOL1	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	-0.35253689622061035	[680]	[280]	-3	hSpCas9	negative selection	11317883
201160742	201160765	2	+	28162770	EOL1	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.6098151780873761	[249]	[200]	5	hSpCas9	negative selection	11317884
201133032	201133055	2	+	28162770	EOL1	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-1.5382428591566775	[214]	[38]	-7	hSpCas9	negative selection	11317885
201133107	201133130	2	+	28162770	EOL1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.10489600632194751	[197]	[96]	-1	hSpCas9	negative selection	11317886
201135983	201136006	2	-	28162770	EOL1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.2564810282039349	[660]	[415]	2	hSpCas9	negative selection	11317887
201136061	201136084	2	-	28162770	EOL1	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-0.3907165930358172	[1079]	[433]	-3	hSpCas9	negative selection	11317888
201160563	201160586	2	+	28162770	EOL1	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	0.2977650951547513	[314]	[203]	2	hSpCas9	negative selection	11317889
201160606	201160629	2	+	28162770	EOL1	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-0.4454018381797711	[167]	[64]	-3	hSpCas9	negative selection	11317890
201133093	201133116	2	+	28162770	MOLM13	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.536060884186158	[433]	[454]	4	hSpCas9	negative selection	11487249
201160742	201160765	2	+	28162770	MOLM13	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.31371845141681853	[295]	[265]	2	hSpCas9	negative selection	11487250
201133032	201133055	2	+	28162770	MOLM13	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-1.6169995160419341	[139]	[32]	-7	hSpCas9	negative selection	11487251
201133107	201133130	2	+	28162770	MOLM13	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.510958103436465	[164]	[169]	4	hSpCas9	negative selection	11487252
201135983	201136006	2	-	28162770	MOLM13	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.4771226613226158	[622]	[626]	3	hSpCas9	negative selection	11487253
201136061	201136084	2	-	28162770	MOLM13	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-1.0628864328005365	[1227]	[424]	-5	hSpCas9	negative selection	11487254
201160563	201160586	2	+	28162770	MOLM13	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.30308510478652617	[371]	[217]	-2	hSpCas9	negative selection	11487255
201160606	201160629	2	+	28162770	MOLM13	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-1.7349275014551082	[243]	[52]	-7	hSpCas9	negative selection	11487256
201133093	201133116	2	+	28162770	HEL	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.5217977948461718	[484]	[445]	4	hSpCas9	negative selection	11656615
201160742	201160765	2	+	28162770	HEL	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	-0.6224998447601668	[261]	[108]	-4	hSpCas9	negative selection	11656616
201133032	201133055	2	+	28162770	HEL	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-1.5486872386528776	[168]	[36]	-7	hSpCas9	negative selection	11656617
201133107	201133130	2	+	28162770	HEL	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.7722986672784867	[127]	[47]	-5	hSpCas9	negative selection	11656618
201135983	201136006	2	-	28162770	HEL	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.714738555862892	[468]	[492]	6	hSpCas9	negative selection	11656619
201136061	201136084	2	-	28162770	HEL	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-0.8810008068010013	[1014]	[352]	-5	hSpCas9	negative selection	11656620
201160563	201160586	2	+	28162770	HEL	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.4342231498145272	[307]	[145]	-3	hSpCas9	negative selection	11656621
201160606	201160629	2	+	28162770	HEL	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-1.0055496040896283	[162]	[51]	-6	hSpCas9	negative selection	11656622
201133093	201133116	2	+	28162770	MV411	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.8921062976281993	[354]	[554]	7	hSpCas9	negative selection	11825981
201160742	201160765	2	+	28162770	MV411	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.2823713408921624	[203]	[208]	2	hSpCas9	negative selection	11825982
201133032	201133055	2	+	28162770	MV411	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-0.5395687258830264	[87]	[50]	-4	hSpCas9	negative selection	11825983
201133107	201133130	2	+	28162770	MV411	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	1.0037684698159126	[73]	[124]	8	hSpCas9	negative selection	11825984
201135983	201136006	2	-	28162770	MV411	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	1.0106346865221612	[326]	[554]	8	hSpCas9	negative selection	11825985
201136061	201136084	2	-	28162770	MV411	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	0.05074563977767732	[713]	[622]	0	hSpCas9	negative selection	11825986
201160563	201160586	2	+	28162770	MV411	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.047396883222312086	[210]	[171]	0	hSpCas9	negative selection	11825987
201160606	201160629	2	+	28162770	MV411	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	0.6022802681428728	[103]	[132]	5	hSpCas9	negative selection	11825988
201133093	201133116	2	+	28162770	MONOMAC1	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.17566581506093493	[267]	[346]	1	hSpCas9	negative selection	11995347
201160742	201160765	2	+	28162770	MONOMAC1	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	-1.0211870116601358	[107]	[60]	-7	hSpCas9	negative selection	11995348
201133032	201133055	2	+	28162770	MONOMAC1	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-2.93954062476719	[86]	[12]	-9	hSpCas9	negative selection	11995349
201133107	201133130	2	+	28162770	MONOMAC1	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	-0.5913157861716001	[91]	[69]	-5	hSpCas9	negative selection	11995350
201135983	201136006	2	-	28162770	MONOMAC1	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.3543176392496431	[212]	[190]	-3	hSpCas9	negative selection	11995351
201136061	201136084	2	-	28162770	MONOMAC1	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-1.7237847338354142	[509]	[176]	-8	hSpCas9	negative selection	11995352
201160563	201160586	2	+	28162770	MONOMAC1	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.49375437914963627	[155]	[126]	-4	hSpCas9	negative selection	11995353
201160606	201160629	2	+	28162770	MONOMAC1	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-0.6853233283690362	[100]	[71]	-5	hSpCas9	negative selection	11995354
201133093	201133116	2	+	28162770	OCIAML2	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.6229695418101303	[68]	[588]	6	hSpCas9	negative selection	12164713
201160742	201160765	2	+	28162770	OCIAML2	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	0.40588712132283844	[31]	[234]	4	hSpCas9	negative selection	12164714
201133032	201133055	2	+	28162770	OCIAML2	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-3.766085708768333	[26]	[10]	-9	hSpCas9	negative selection	12164715
201133107	201133130	2	+	28162770	OCIAML2	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.8023886691642549	[17]	[173]	7	hSpCas9	negative selection	12164716
201135983	201136006	2	-	28162770	OCIAML2	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	0.737478370088039	[57]	[535]	7	hSpCas9	negative selection	12164717
201136061	201136084	2	-	28162770	OCIAML2	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-2.0363987607300067	[167]	[226]	-8	hSpCas9	negative selection	12164718
201160563	201160586	2	+	28162770	OCIAML2	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	0.27012734808641925	[37]	[253]	2	hSpCas9	negative selection	12164719
201160606	201160629	2	+	28162770	OCIAML2	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-1.3610053340676629	[18]	[40]	-7	hSpCas9	negative selection	12164720
201133093	201133116	2	+	28162770	OCIAML3	viability	ATGAAGGATTACATGGGCCGAGG	CFLAR	ENSG00000003402	0.503603156302259	[99]	[427]	4	hSpCas9	negative selection	12334079
201160742	201160765	2	+	28162770	OCIAML3	viability	GGACAGCAGCCTCTTGGAGGTGG	CFLAR	ENSG00000003402	-0.17897014104531941	[68]	[183]	-1	hSpCas9	negative selection	12334080
201133032	201133055	2	+	28162770	OCIAML3	viability	GCTGATGGCAGAGATTGGTGAGG	CFLAR	ENSG00000003402	-2.548203950711038	[30]	[15]	-9	hSpCas9	negative selection	12334081
201133107	201133130	2	+	28162770	OCIAML3	viability	GGGCCGAGGCAAGATAAGCAAGG	CFLAR	ENSG00000003402	0.5835305452280243	[20]	[94]	5	hSpCas9	negative selection	12334082
201135983	201136006	2	-	28162770	OCIAML3	viability	GTTTCTCCAACTCAACCACAAGG	CFLAR	ENSG00000003402	-0.356968443023314	[111]	[263]	-3	hSpCas9	negative selection	12334083
201136061	201136084	2	-	28162770	OCIAML3	viability	TTGTCTTCAGGTCTATTCTGTGG	CFLAR	ENSG00000003402	-0.07495457961626029	[208]	[598]	0	hSpCas9	negative selection	12334084
201160563	201160586	2	+	28162770	OCIAML3	viability	GTGTGTGTCCTGGTGAGCCGAGG	CFLAR	ENSG00000003402	-0.44276405994792584	[94]	[210]	-3	hSpCas9	negative selection	12334085
201160606	201160629	2	+	28162770	OCIAML3	viability	GTGTGGATCAGACTCACTCAGGG	CFLAR	ENSG00000003402	-0.9565777197088713	[35]	[55]	-6	hSpCas9	negative selection	12334086