Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1128
• Symbol:CHRM1
• Description:cholinergic receptor muscarinic 1

DataSource: http://genomecrispr.dkfz.de/#!/results/CHRM1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
62921710	62921733	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACAGGGGCTGGGGGCTCTAAGG	CHRM1	ENSG00000168539	0.1244193776072513	[33,33]	[6,7]	0	dCas9-VP64	positive selection	2384649
62921630	62921653	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCACACCCACTGCACAGACCCGG	CHRM1	ENSG00000168539	-0.41319225581501884	[95,77]	[12,14]	-2	dCas9-VP64	positive selection	2384650
62921648	62921671	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGGGTGTGTGTGCCGCCGGG	CHRM1	ENSG00000168539	2.21387618897944	[42,22]	[14,52]	7	dCas9-VP64	positive selection	2384651
62921710	62921733	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACAGGGGCTGGGGGCTCTAAGG	CHRM1	ENSG00000168539	8.491809446854623	[16,13]	[15,3626]	9	dCas9-VP64	positive selection	2479904
62921630	62921653	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCACACCCACTGCACAGACCCGG	CHRM1	ENSG00000168539	-0.8279741344721445	[133,428]	[57,44]	-7	dCas9-VP64	positive selection	2479905
62921648	62921671	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGGGTGTGTGTGCCGCCGGG	CHRM1	ENSG00000168539	-0.11322079670614293	[38,57]	[6,20]	-1	dCas9-VP64	positive selection	2479906
62921310	62921333	11	+	27661255	K562	viability	GGGGGAGCTGCGCCCTGTGCTGG	CHRM1	ENSG00000168539	0.03962353821792164	[1319,1649]	[1391,1062]	1	dCas9-KRAB	negative selection	5470862
62921338	62921361	11	+	27661255	K562	viability	GGAGAGGCACAGCCAGTGATTGG	CHRM1	ENSG00000168539	0.10902340562004453	[1808,1894]	[1706,1497]	4	dCas9-KRAB	negative selection	5470863
62921166	62921189	11	-	27661255	K562	viability	GCTGCACTAAGGTAGAGGGTAGG	CHRM1	ENSG00000168539	0.07470518682768906	[526,594]	[559,394]	2	dCas9-KRAB	negative selection	5470864
62921260	62921283	11	-	27661255	K562	viability	GACGCCGCAGGCCCCCAGGGAGG	CHRM1	ENSG00000168539	0.051913893397891764	[663,671]	[572,535]	1	dCas9-KRAB	negative selection	5470865
62921263	62921286	11	-	27661255	K562	viability	GGAGACGCCGCAGGCCCCCAGGG	CHRM1	ENSG00000168539	0.09861561409450692	[884,852]	[861,642]	3	dCas9-KRAB	negative selection	5470866
62921350	62921373	11	-	27661255	K562	viability	GGGTGGGACATGCCAATCACTGG	CHRM1	ENSG00000168539	0.246771491202341	[843,963]	[911,805]	8	dCas9-KRAB	negative selection	5470867