Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1131
• Symbol:CHRM3
• Description:cholinergic receptor muscarinic 3

DataSource: http://genomecrispr.dkfz.de/#!/results/CHRM3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
239907477	239907500	1	-	26472758	Jiyoye	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	1.667042508260984	[37]	[90]	8	hSpCas9	negative selection	31642
239908389	239908412	1	+	26472758	Jiyoye	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.8353949217682048	[167]	[70]	-5	hSpCas9	negative selection	31643
239907504	239907527	1	-	26472758	Jiyoye	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	1.6702097873396675	[14]	[35]	8	hSpCas9	negative selection	31644
239907520	239907543	1	-	26472758	Jiyoye	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	1.3002601775893616	[104]	[194]	7	hSpCas9	negative selection	31645
239907540	239907563	1	-	26472758	Jiyoye	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.2227508103684459	[324]	[285]	1	hSpCas9	negative selection	31646
239907626	239907649	1	-	26472758	Jiyoye	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.5418249082006554	[275]	[302]	4	hSpCas9	negative selection	31647
239907912	239907935	1	-	26472758	Jiyoye	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.4499250289652105	[132]	[136]	3	hSpCas9	negative selection	31648
239908100	239908123	1	-	26472758	Jiyoye	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	-0.2865454342619266	[240]	[148]	-2	hSpCas9	negative selection	31649
239908137	239908160	1	-	26472758	Jiyoye	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.36575545412589283	[211]	[205]	2	hSpCas9	negative selection	31650
239908299	239908322	1	-	26472758	Jiyoye	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.9217485543356316	[34]	[49]	6	hSpCas9	negative selection	31651
239907477	239907500	1	-	26472758	KBM7	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	-0.10267689809548358	[432,360]	[199,148]	-1	hSpCas9	negative selection	222760
239908389	239908412	1	+	26472758	KBM7	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.40232588886105036	[513,395]	[178,370]	4	hSpCas9	negative selection	222761
239907504	239907527	1	-	26472758	KBM7	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.09304404424069723	[225,174]	[93,81]	-1	hSpCas9	negative selection	222762
239907520	239907543	1	-	26472758	KBM7	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.5552155022978299	[653,430]	[212,507]	6	hSpCas9	negative selection	222763
239907540	239907563	1	-	26472758	KBM7	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.7407987457311793	[1290,738]	[727,824]	7	hSpCas9	negative selection	222764
239907626	239907649	1	-	26472758	KBM7	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.5440744565555945	[924,617]	[506,532]	6	hSpCas9	negative selection	222765
239907912	239907935	1	-	26472758	KBM7	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-0.3009113921819643	[505,425]	[192,162]	-3	hSpCas9	negative selection	222766
239908100	239908123	1	-	26472758	KBM7	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.9907206547179365	[766,478]	[652,497]	9	hSpCas9	negative selection	222767
239908137	239908160	1	-	26472758	KBM7	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.7949660073401996	[719,776]	[474,741]	8	hSpCas9	negative selection	222768
239908299	239908322	1	-	26472758	KBM7	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	1.3149471726654174	[229,194]	[243,250]	9	hSpCas9	negative selection	222769
239907477	239907500	1	-	26472758	Raji	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.6923460360947558	[279]	[104]	6	hSpCas9	negative selection	413878
239908389	239908412	1	+	26472758	Raji	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.5308771915076058	[192]	[30]	-4	hSpCas9	negative selection	413879
239907504	239907527	1	-	26472758	Raji	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.4004111048250968	[181]	[31]	-3	hSpCas9	negative selection	413880
239907520	239907543	1	-	26472758	Raji	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.438104748718968	[228]	[71]	4	hSpCas9	negative selection	413881
239907540	239907563	1	-	26472758	Raji	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.7112240463004452	[328]	[124]	6	hSpCas9	negative selection	413882
239907626	239907649	1	-	26472758	Raji	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.6883441055372594	[360]	[134]	6	hSpCas9	negative selection	413883
239907912	239907935	1	-	26472758	Raji	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-0.1556508704601945	[287]	[59]	-1	hSpCas9	negative selection	413884
239908100	239908123	1	-	26472758	Raji	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	-0.3951168051555839	[526]	[92]	-3	hSpCas9	negative selection	413885
239908137	239908160	1	-	26472758	Raji	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.0861843696677671	[616]	[151]	0	hSpCas9	negative selection	413886
239908299	239908322	1	-	26472758	Raji	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.6457792863204082	[208]	[30]	-5	hSpCas9	negative selection	413887
239907477	239907500	1	-	26472758	K562	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.8100159035206719	[374]	[554]	6	hSpCas9	negative selection	604996
239908389	239908412	1	+	26472758	K562	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.41295226858275946	[428]	[271]	-3	hSpCas9	negative selection	604997
239907504	239907527	1	-	26472758	K562	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.7289461458300863	[160]	[81]	-4	hSpCas9	negative selection	604998
239907520	239907543	1	-	26472758	K562	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.490682552621737	[547]	[649]	4	hSpCas9	negative selection	604999
239907540	239907563	1	-	26472758	K562	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.44555859977429835	[634]	[729]	3	hSpCas9	negative selection	605000
239907626	239907649	1	-	26472758	K562	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.8392351291297322	[534]	[807]	7	hSpCas9	negative selection	605001
239907912	239907935	1	-	26472758	K562	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.36014643471994706	[442]	[479]	3	hSpCas9	negative selection	605002
239908100	239908123	1	-	26472758	K562	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.8829995817619172	[536]	[835]	7	hSpCas9	negative selection	605003
239908137	239908160	1	-	26472758	K562	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.9313961860009767	[645]	[1039]	7	hSpCas9	negative selection	605004
239908299	239908322	1	-	26472758	K562	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-1.5629361943911573	[188]	[53]	-7	hSpCas9	negative selection	605005
239907778	239907801	1	-	26627737	DLD1	viability	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.2717700180304362	[234]	[58,122,85]	3	hSpCas9	negative selection	769907
239907877	239907900	1	-	26627737	DLD1	viability	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.7324652951807974	[854]	[153,156,169]	-6	hSpCas9	negative selection	769908
239908299	239908322	1	-	26627737	DLD1	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.8278417628377639	[152]	[19,107,121]	7	hSpCas9	negative selection	769909
239908492	239908515	1	+	26627737	DLD1	viability	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.12744189840447828	[867]	[316,325,253]	1	hSpCas9	negative selection	769910
239908679	239908702	1	+	26627737	DLD1	viability	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.9013759284065503	[1251]	[140,456,63]	-7	hSpCas9	negative selection	769911
239907778	239907801	1	-	26627737	GBM cells	viability after 5 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.006271284182177164	[232]	[120,129]	0	hSpCas9	negative selection	852222
239907877	239907900	1	-	26627737	GBM cells	viability after 5 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.05004669211384882	[360]	[177,195]	-1	hSpCas9	negative selection	852223
239908299	239908322	1	-	26627737	GBM cells	viability after 5 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.07256196237071544	[85]	[58,37]	1	hSpCas9	negative selection	852224
239908492	239908515	1	+	26627737	GBM cells	viability after 5 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	-0.06338541592909086	[490]	[265,237]	-1	hSpCas9	negative selection	852225
239908679	239908702	1	+	26627737	GBM cells	viability after 5 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.3085745395131103	[320]	[144,132]	-5	hSpCas9	negative selection	852226
239907778	239907801	1	-	26627737	GBM cells	viability after 13 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.0075840754719545544	[232]	[122,127]	0	hSpCas9	negative selection	934537
239907877	239907900	1	-	26627737	GBM cells	viability after 13 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.02294472903548217	[360]	[237,155]	0	hSpCas9	negative selection	934538
239908299	239908322	1	-	26627737	GBM cells	viability after 13 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.061208942626780116	[85]	[35,58]	0	hSpCas9	negative selection	934539
239908492	239908515	1	+	26627737	GBM cells	viability after 13 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.022440009642895054	[490]	[408,157]	0	hSpCas9	negative selection	934540
239908679	239908702	1	+	26627737	GBM cells	viability after 13 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.5329343757003964	[320]	[110,127]	-6	hSpCas9	negative selection	934541
239907778	239907801	1	-	26627737	GBM cells	viability after 21 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.37202638891667134	[232]	[113,82]	-3	hSpCas9	negative selection	1016852
239907877	239907900	1	-	26627737	GBM cells	viability after 21 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.01713118335800501	[360]	[210,186]	0	hSpCas9	negative selection	1016853
239908299	239908322	1	-	26627737	GBM cells	viability after 21 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.7199221207811142	[85]	[77,75]	7	hSpCas9	negative selection	1016854
239908492	239908515	1	+	26627737	GBM cells	viability after 21 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.46037769214746793	[490]	[389,345]	5	hSpCas9	negative selection	1016855
239908679	239908702	1	+	26627737	GBM cells	viability after 21 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.5952801109179349	[320]	[116,113]	-5	hSpCas9	negative selection	1016856
239907778	239907801	1	-	26627737	RPE1	viability after 9 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.7008280068599899	[491]	[152,375]	4	hSpCas9	negative selection	1099167
239907877	239907900	1	-	26627737	RPE1	viability after 9 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.7330677414346443	[654]	[356,319]	5	hSpCas9	negative selection	1099168
239908299	239908322	1	-	26627737	RPE1	viability after 9 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.10893006562419894	[192]	[38,77]	-1	hSpCas9	negative selection	1099169
239908492	239908515	1	+	26627737	RPE1	viability after 9 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	-0.010332738605940639	[2063]	[641,640]	0	hSpCas9	negative selection	1099170
239908679	239908702	1	+	26627737	RPE1	viability after 9 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.30763744448999647	[1042]	[380,433]	2	hSpCas9	negative selection	1099171
239907778	239907801	1	-	26627737	RPE1	viability after 12 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.2610254315261453	[491]	[103,215]	1	hSpCas9	negative selection	1181482
239907877	239907900	1	-	26627737	RPE1	viability after 12 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.6285262118596968	[654]	[256,287]	4	hSpCas9	negative selection	1181483
239908299	239908322	1	-	26627737	RPE1	viability after 12 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.8507692445048542	[192]	[76,110]	5	hSpCas9	negative selection	1181484
239908492	239908515	1	+	26627737	RPE1	viability after 12 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	-0.1571017797759291	[2063]	[558,431]	-1	hSpCas9	negative selection	1181485
239908679	239908702	1	+	26627737	RPE1	viability after 12 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.17101883800034495	[1042]	[314,315]	1	hSpCas9	negative selection	1181486
239907778	239907801	1	-	26627737	RPE1	viability after 15 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.7267665313059031	[491]	[211,247]	4	hSpCas9	negative selection	1263797
239907877	239907900	1	-	26627737	RPE1	viability after 15 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.1896455938710619	[654]	[277,146]	1	hSpCas9	negative selection	1263798
239908299	239908322	1	-	26627737	RPE1	viability after 15 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.14534690746207657	[192]	[66,53]	1	hSpCas9	negative selection	1263799
239908492	239908515	1	+	26627737	RPE1	viability after 15 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.2393459741785593	[2063]	[957,429]	1	hSpCas9	negative selection	1263800
239908679	239908702	1	+	26627737	RPE1	viability after 15 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.36096078369591983	[1042]	[467,292]	2	hSpCas9	negative selection	1263801
239907778	239907801	1	-	26627737	RPE1	viability after 18 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.1521224865514803	[491]	[89,150]	-1	hSpCas9	negative selection	1346112
239907877	239907900	1	-	26627737	RPE1	viability after 18 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.6257713512077027	[654]	[250,295]	4	hSpCas9	negative selection	1346113
239908299	239908322	1	-	26627737	RPE1	viability after 18 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.966751240861184	[192]	[124,76]	6	hSpCas9	negative selection	1346114
239908492	239908515	1	+	26627737	RPE1	viability after 18 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	-0.29048443761094456	[2063]	[496,410]	-2	hSpCas9	negative selection	1346115
239908679	239908702	1	+	26627737	RPE1	viability after 18 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.06875858084757469	[1042]	[213,381]	0	hSpCas9	negative selection	1346116
239907778	239907801	1	-	26627737	HeLa	viability after 8 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.27156620853417357	[279]	[15,135,129]	-3	hSpCas9	negative selection	1428427
239907877	239907900	1	-	26627737	HeLa	viability after 8 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.0914141463658712	[659]	[203,168,410]	-1	hSpCas9	negative selection	1428428
239908299	239908322	1	-	26627737	HeLa	viability after 8 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.2586447724529778	[192]	[165,36,111]	2	hSpCas9	negative selection	1428429
239908492	239908515	1	+	26627737	HeLa	viability after 8 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	-0.29695852489717883	[616]	[212,320,126]	-3	hSpCas9	negative selection	1428430
239908679	239908702	1	+	26627737	HeLa	viability after 8 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.24815055022655155	[447]	[256,119,316]	2	hSpCas9	negative selection	1428431
239907778	239907801	1	-	26627737	HeLa	viability after 12 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.3067648730764306	[279]	[194,94,145]	2	hSpCas9	negative selection	1510742
239907877	239907900	1	-	26627737	HeLa	viability after 12 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.6634080230083523	[659]	[160,127,231]	-5	hSpCas9	negative selection	1510743
239908299	239908322	1	-	26627737	HeLa	viability after 12 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.3640867497916995	[192]	[132,23,34]	-3	hSpCas9	negative selection	1510744
239908492	239908515	1	+	26627737	HeLa	viability after 12 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.21997646931238668	[616]	[173,460,234]	2	hSpCas9	negative selection	1510745
239908679	239908702	1	+	26627737	HeLa	viability after 12 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.5426813732056317	[447]	[298,353,147]	4	hSpCas9	negative selection	1510746
239907778	239907801	1	-	26627737	HeLa	viability after 15 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.20427120817609645	[279]	[108,84,102]	-2	hSpCas9	negative selection	1593057
239907877	239907900	1	-	26627737	HeLa	viability after 15 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.45701407326970234	[659]	[308,77,198]	-4	hSpCas9	negative selection	1593058
239908299	239908322	1	-	26627737	HeLa	viability after 15 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.6470422460108733	[192]	[180,104,78]	5	hSpCas9	negative selection	1593059
239908492	239908515	1	+	26627737	HeLa	viability after 15 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.47911556005838263	[616]	[299,400,349]	4	hSpCas9	negative selection	1593060
239908679	239908702	1	+	26627737	HeLa	viability after 15 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.38972671222167027	[447]	[64,160,196]	-3	hSpCas9	negative selection	1593061
239907778	239907801	1	-	26627737	HeLa	viability after 18 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.2564890702866899	[279]	[64,71,102]	-2	hSpCas9	negative selection	1675372
239907877	239907900	1	-	26627737	HeLa	viability after 18 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.4012592397912877	[659]	[221,64,198]	-3	hSpCas9	negative selection	1675373
239908299	239908322	1	-	26627737	HeLa	viability after 18 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.6745124745347975	[192]	[125,86,78]	5	hSpCas9	negative selection	1675374
239908492	239908515	1	+	26627737	HeLa	viability after 18 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.4699331220401394	[616]	[192,336,349]	4	hSpCas9	negative selection	1675375
239908679	239908702	1	+	26627737	HeLa	viability after 18 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.39219343375174676	[447]	[44,130,196]	-3	hSpCas9	negative selection	1675376
239907778	239907801	1	-	26627737	HCT116	viability after 6 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-1.3612128219834703	[555]	[24,38]	-7	hSpCas9	negative selection	1757687
239907877	239907900	1	-	26627737	HCT116	viability after 6 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-1.1055410155183787	[1352]	[210,36]	-6	hSpCas9	negative selection	1757688
239908299	239908322	1	-	26627737	HCT116	viability after 6 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	2.4872801025018534	[194]	[22,253]	9	hSpCas9	negative selection	1757689
239908492	239908515	1	+	26627737	HCT116	viability after 6 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.8842658401311816	[949]	[673,55]	5	hSpCas9	negative selection	1757690
239908679	239908702	1	+	26627737	HCT116	viability after 6 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	1.4025803553923288	[556]	[313,185]	7	hSpCas9	negative selection	1757691
239907778	239907801	1	-	26627737	HCT116	viability after 8 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.1714088984087065	[235]	[164,123,58]	-2	hSpCas9	negative selection	1840002
239907877	239907900	1	-	26627737	HCT116	viability after 8 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.08742553306383116	[483]	[232,208,309]	-1	hSpCas9	negative selection	1840003
239908299	239908322	1	-	26627737	HCT116	viability after 8 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	1.602835160057111	[35]	[29,71,77]	9	hSpCas9	negative selection	1840004
239908492	239908515	1	+	26627737	HCT116	viability after 8 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.44181010229182904	[454]	[415,183,421]	4	hSpCas9	negative selection	1840005
239908679	239908702	1	+	26627737	HCT116	viability after 8 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.8571669491695133	[509]	[141,153,168]	-8	hSpCas9	negative selection	1840006
239907778	239907801	1	-	26627737	HCT116	viability after 9 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.5250234457049764	[555]	[240,191]	4	hSpCas9	negative selection	1922317
239907877	239907900	1	-	26627737	HCT116	viability after 9 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.11453675170121302	[1352]	[388,289]	-1	hSpCas9	negative selection	1922318
239908299	239908322	1	-	26627737	HCT116	viability after 9 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.9835222549401954	[194]	[46,9]	-6	hSpCas9	negative selection	1922319
239908492	239908515	1	+	26627737	HCT116	viability after 9 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.3723422734931642	[949]	[405,266]	2	hSpCas9	negative selection	1922320
239908679	239908702	1	+	26627737	HCT116	viability after 9 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	1.06648205858855	[556]	[468,186]	7	hSpCas9	negative selection	1922321
239907778	239907801	1	-	26627737	HCT116	viability after 12 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.5608419497646082	[235]	[161,112,273]	5	hSpCas9	negative selection	2004632
239907877	239907900	1	-	26627737	HCT116	viability after 12 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.18421986706638205	[483]	[329,313,219]	2	hSpCas9	negative selection	2004633
239908299	239908322	1	-	26627737	HCT116	viability after 12 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	1.5999429962331482	[35]	[49,69,52]	9	hSpCas9	negative selection	2004634
239908492	239908515	1	+	26627737	HCT116	viability after 12 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.5287635511429094	[454]	[326,324,383]	5	hSpCas9	negative selection	2004635
239908679	239908702	1	+	26627737	HCT116	viability after 12 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-1.0711465160455353	[509]	[125,134,121]	-8	hSpCas9	negative selection	2004636
239907778	239907801	1	-	26627737	HCT116	viability after 15 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.7572065729166955	[235]	[377,150,176]	6	hSpCas9	negative selection	2086947
239907877	239907900	1	-	26627737	HCT116	viability after 15 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.30790538265441836	[483]	[331,537,162]	3	hSpCas9	negative selection	2086948
239908299	239908322	1	-	26627737	HCT116	viability after 15 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	1.0733067169265973	[35]	[70,30,31]	8	hSpCas9	negative selection	2086949
239908492	239908515	1	+	26627737	HCT116	viability after 15 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.23413349387126692	[454]	[258,336,319]	2	hSpCas9	negative selection	2086950
239908679	239908702	1	+	26627737	HCT116	viability after 15 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.011280110935557919	[509]	[288,232,361]	0	hSpCas9	negative selection	2086951
239907778	239907801	1	-	26627737	HCT116	viability after 18 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.7757938300950646	[235]	[257,109,224]	6	hSpCas9	negative selection	2169262
239907877	239907900	1	-	26627737	HCT116	viability after 18 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.6406599416346365	[483]	[470,435,173]	5	hSpCas9	negative selection	2169263
239908299	239908322	1	-	26627737	HCT116	viability after 18 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.18138678046978862	[35]	[27,0,31]	1	hSpCas9	negative selection	2169264
239908492	239908515	1	+	26627737	HCT116	viability after 18 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.6953804361716276	[454]	[340,418,301]	6	hSpCas9	negative selection	2169265
239908679	239908702	1	+	26627737	HCT116	viability after 18 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.6048018352776316	[509]	[219,115,152]	-5	hSpCas9	negative selection	2169266
239874804	239874827	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCGGGAGGCTGAGGCGGGACAG	CHRM3	ENSG00000133019	2.025250103485989	[67,16]	[67,5]	7	dCas9-VP64	positive selection	2395006
239488511	239488534	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACCATCCTGGCTAACAAAG	CHRM3	ENSG00000133019	-0.7007848477191231	[357,35]	[27,23]	-4	dCas9-VP64	positive selection	2404323
239568200	239568223	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACAGCCAAACCATATTACTGG	CHRM3	ENSG00000133019	0.8739034770311811	[240,269]	[9,202]	3	dCas9-VP64	positive selection	2418167
239519956	239519979	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGATCGAGACCATCCGGG	CHRM3	ENSG00000133019	-0.5760906316419423	[119,210]	[24,22]	-3	dCas9-VP64	positive selection	2418454
239643307	239643330	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGACATTTAAGTCTGCAGTGG	CHRM3	ENSG00000133019	0.7916196845249337	[134,243]	[42,103]	3	dCas9-VP64	positive selection	2419381
239618802	239618825	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAGTGCAGGGG	CHRM3	ENSG00000133019	-0.49998316673352905	[290,357]	[69,28]	-2	dCas9-VP64	positive selection	2425306
239494614	239494637	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATAGGTGCAGCAAACCACCAGGG	CHRM3	ENSG00000133019	9.45620005017045	[53,84]	[18082,3082]	9	dCas9-VP64	positive selection	2426885
239668273	239668296	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGATGGGTTTTCACCATGTTAG	CHRM3	ENSG00000133019	3.916189069033361	[314,93]	[113,1282]	9	dCas9-VP64	positive selection	2433935
239541608	239541631	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCTTCCACCTCAG	CHRM3	ENSG00000133019	-1.437181231551541	[165,262]	[21,11]	-8	dCas9-VP64	positive selection	2441654
239866125	239866148	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGCACTTTGGGAGGCCGGGG	CHRM3	ENSG00000133019	0.17643232981432222	[5,22]	[1,4]	0	dCas9-VP64	positive selection	2447732
239401563	239401586	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCCGCCTTCCGG	CHRM3	ENSG00000133019	0.2792775090634416	[552,542]	[69,227]	1	dCas9-VP64	positive selection	2464366
239447571	239447594	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGACCAGCCTGACCAACATGG	CHRM3	ENSG00000133019	-1.5081130691523483	[299,84]	[22,3]	-8	dCas9-VP64	positive selection	2464714
239490949	239490972	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTGGG	CHRM3	ENSG00000133019	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469934
239874804	239874827	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCGGGAGGCTGAGGCGGGACAG	CHRM3	ENSG00000133019	-0.11854306132123821	[57,168]	[14,50]	-1	dCas9-VP64	positive selection	2490261
239488511	239488534	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACCATCCTGGCTAACAAAG	CHRM3	ENSG00000133019	0.5549091022422933	[154,188]	[77,85]	4	dCas9-VP64	positive selection	2499578
239568200	239568223	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACAGCCAAACCATATTACTGG	CHRM3	ENSG00000133019	0.09301312862040967	[177,334]	[71,103]	0	dCas9-VP64	positive selection	2513422
239519956	239519979	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGATCGAGACCATCCGGG	CHRM3	ENSG00000133019	-0.5911896850137947	[183,271]	[71,26]	-6	dCas9-VP64	positive selection	2513709
239643307	239643330	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGACATTTAAGTCTGCAGTGG	CHRM3	ENSG00000133019	-0.5761746865528519	[375,276]	[90,52]	-6	dCas9-VP64	positive selection	2514636
239618802	239618825	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAGTGCAGGGG	CHRM3	ENSG00000133019	0.5593039216911941	[271,243]	[52,190]	4	dCas9-VP64	positive selection	2520561
239494614	239494637	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATAGGTGCAGCAAACCACCAGGG	CHRM3	ENSG00000133019	1.9932270680514117	[357,195]	[283,435]	8	dCas9-VP64	positive selection	2522140
239668273	239668296	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGATGGGTTTTCACCATGTTAG	CHRM3	ENSG00000133019	2.0642303287003654	[37,60]	[95,40]	8	dCas9-VP64	positive selection	2529190
239541608	239541631	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCTTCCACCTCAG	CHRM3	ENSG00000133019	0.43444246644375656	[171,135]	[90,46]	3	dCas9-VP64	positive selection	2536909
239866125	239866148	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGCACTTTGGGAGGCCGGGG	CHRM3	ENSG00000133019	-1.1255792224366725	[173,43]	[24,6]	-9	dCas9-VP64	positive selection	2542987
239401563	239401586	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCCGCCTTCCGG	CHRM3	ENSG00000133019	0.2904267335704165	[840,610]	[251,326]	2	dCas9-VP64	positive selection	2559621
239447571	239447594	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGACCAGCCTGACCAACATGG	CHRM3	ENSG00000133019	-0.5989378574143126	[229,363]	[80,46]	-6	dCas9-VP64	positive selection	2559969
239490949	239490972	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTGGG	CHRM3	ENSG00000133019	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565189
239907888	239907911	1	-	27260157	DLD1	viability	ATTGCTGGCTACGTAGTCAATGG	CHRM3	ENSG00000133019	0.35840059808415903	[]	[]	4	hSpCas9	negative selection	2577493
239907539	239907562	1	-	27260157	DLD1	viability	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	0.203181079002892	[]	[]	3	hSpCas9	negative selection	2577789
239907664	239907687	1	+	27260157	DLD1	viability	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	0.262513865941611	[]	[]	4	hSpCas9	negative selection	2578326
239907696	239907719	1	-	27260157	DLD1	viability	TACCAGGATGTTGCCGATGATGG	CHRM3	ENSG00000133019	0.79436771549695	[]	[]	9	hSpCas9	negative selection	2581442
239908229	239908252	1	+	27260157	DLD1	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.154895013352869	[]	[]	3	hSpCas9	negative selection	2582701
239908100	239908123	1	-	27260157	DLD1	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	1.16732163496931	[]	[]	9	hSpCas9	negative selection	2584079
239907783	239907806	1	-	27260157	DLD1	viability	CCCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	-0.556888750714195	[]	[]	-4	hSpCas9	negative selection	2607851
239908126	239908149	1	-	27260157	DLD1	viability	AAGTAATGGTGGGCTCACTGAGG	CHRM3	ENSG00000133019	-1.22640984767908	[]	[]	-7	hSpCas9	negative selection	2610443
239907569	239907592	1	+	27260157	DLD1	viability	TACAATGTTTCTCGAGCAGCTGG	CHRM3	ENSG00000133019	-0.443611066276763	[]	[]	-4	hSpCas9	negative selection	2613417
239907782	239907805	1	+	27260157	DLD1	viability	GCCTGTGCCGATCTGATTATCGG	CHRM3	ENSG00000133019	0.649810283479901	[]	[]	8	hSpCas9	negative selection	2623195
239908371	239908394	1	+	27260157	DLD1	viability	AGTATGGCCGCTGCCACTTCTGG	CHRM3	ENSG00000133019	0.0299408000501066	[]	[]	0	hSpCas9	negative selection	2641641
239908297	239908320	1	-	27260157	DLD1	viability	AGCTTCGAGAACTGCCCGTGGGG	CHRM3	ENSG00000133019	0.0887381485051888	[]	[]	3	hSpCas9	negative selection	2641722
239907610	239907633	1	+	27260157	DLD1	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	1.16901887920692	[]	[]	9	hSpCas9	negative selection	2642279
239908415	239908438	1	-	27260157	DLD1	viability	TGGTCCATCTGCTCGGAGCTGGG	CHRM3	ENSG00000133019	0.704222046839822	[]	[]	8	hSpCas9	negative selection	2642329
239907968	239907991	1	-	27260157	DLD1	viability	CGTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	-0.029095168433373	[]	[]	0	hSpCas9	negative selection	2642905
239908344	239908367	1	+	27260157	DLD1	viability	AAAGCATGAAACGCTCCAACAGG	CHRM3	ENSG00000133019	0.849977547262391	[]	[]	9	hSpCas9	negative selection	2644356
239907615	239907638	1	-	27260157	DLD1	viability	ACCTCCCAGAGGGTCATCGGTGG	CHRM3	ENSG00000133019	-0.394567078219846	[]	[]	-3	hSpCas9	negative selection	2646321
239907957	239907980	1	-	27260157	DLD1	viability	GTACGTGAGCGGCCTCGTGATGG	CHRM3	ENSG00000133019	-0.628086472203085	[]	[]	-5	hSpCas9	negative selection	2649278
239907888	239907911	1	-	27260157	HT1080	viability	ATTGCTGGCTACGTAGTCAATGG	CHRM3	ENSG00000133019	0.107734655237014	[]	[]	1	hSpCas9	negative selection	2653623
239907539	239907562	1	-	27260157	HT1080	viability	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	0.414810976797162	[]	[]	4	hSpCas9	negative selection	2653919
239907664	239907687	1	+	27260157	HT1080	viability	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	-0.358373920991427	[]	[]	-7	hSpCas9	negative selection	2654456
239907696	239907719	1	-	27260157	HT1080	viability	TACCAGGATGTTGCCGATGATGG	CHRM3	ENSG00000133019	0.905637134104355	[]	[]	7	hSpCas9	negative selection	2657572
239908229	239908252	1	+	27260157	HT1080	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.422979989526843	[]	[]	-7	hSpCas9	negative selection	2658831
239908100	239908123	1	-	27260157	HT1080	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	-0.293679231404959	[]	[]	-7	hSpCas9	negative selection	2660209
239907783	239907806	1	-	27260157	HT1080	viability	CCCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	-0.329994844551987	[]	[]	-7	hSpCas9	negative selection	2683981
239908126	239908149	1	-	27260157	HT1080	viability	AAGTAATGGTGGGCTCACTGAGG	CHRM3	ENSG00000133019	-0.0584058646533033	[]	[]	0	hSpCas9	negative selection	2686573
239907569	239907592	1	+	27260157	HT1080	viability	TACAATGTTTCTCGAGCAGCTGG	CHRM3	ENSG00000133019	-0.453413017961528	[]	[]	-7	hSpCas9	negative selection	2689547
239907782	239907805	1	+	27260157	HT1080	viability	GCCTGTGCCGATCTGATTATCGG	CHRM3	ENSG00000133019	0.505673163068933	[]	[]	4	hSpCas9	negative selection	2699325
239908371	239908394	1	+	27260157	HT1080	viability	AGTATGGCCGCTGCCACTTCTGG	CHRM3	ENSG00000133019	0.77990584555963	[]	[]	6	hSpCas9	negative selection	2717771
239908297	239908320	1	-	27260157	HT1080	viability	AGCTTCGAGAACTGCCCGTGGGG	CHRM3	ENSG00000133019	0.27535731269543	[]	[]	2	hSpCas9	negative selection	2717852
239907610	239907633	1	+	27260157	HT1080	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-0.116483332248065	[]	[]	0	hSpCas9	negative selection	2718409
239908415	239908438	1	-	27260157	HT1080	viability	TGGTCCATCTGCTCGGAGCTGGG	CHRM3	ENSG00000133019	1.81259622378639	[]	[]	9	hSpCas9	negative selection	2718459
239907968	239907991	1	-	27260157	HT1080	viability	CGTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	-0.299593878391532	[]	[]	-7	hSpCas9	negative selection	2719035
239908344	239908367	1	+	27260157	HT1080	viability	AAAGCATGAAACGCTCCAACAGG	CHRM3	ENSG00000133019	1.24786903208862	[]	[]	8	hSpCas9	negative selection	2720486
239907615	239907638	1	-	27260157	HT1080	viability	ACCTCCCAGAGGGTCATCGGTGG	CHRM3	ENSG00000133019	-0.00404575576971057	[]	[]	0	hSpCas9	negative selection	2722451
239907957	239907980	1	-	27260157	HT1080	viability	GTACGTGAGCGGCCTCGTGATGG	CHRM3	ENSG00000133019	-0.993136199985592	[]	[]	-8	hSpCas9	negative selection	2725408
239907888	239907911	1	-	27260157	MKN45	viability	ATTGCTGGCTACGTAGTCAATGG	CHRM3	ENSG00000133019	-0.0579442110551838	[]	[]	0	hSpCas9	negative selection	2729753
239907539	239907562	1	-	27260157	MKN45	viability	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	-0.349797288886319	[]	[]	-1	hSpCas9	negative selection	2730049
239907664	239907687	1	+	27260157	MKN45	viability	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	-0.744029535687666	[]	[]	-7	hSpCas9	negative selection	2730586
239907696	239907719	1	-	27260157	MKN45	viability	TACCAGGATGTTGCCGATGATGG	CHRM3	ENSG00000133019	0.820763292663876	[]	[]	8	hSpCas9	negative selection	2733702
239908229	239908252	1	+	27260157	MKN45	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.813428479337453	[]	[]	8	hSpCas9	negative selection	2734961
239908100	239908123	1	-	27260157	MKN45	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.115007013446053	[]	[]	4	hSpCas9	negative selection	2736339
239907783	239907806	1	-	27260157	MKN45	viability	CCCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.229455626195187	[]	[]	5	hSpCas9	negative selection	2760111
239908126	239908149	1	-	27260157	MKN45	viability	AAGTAATGGTGGGCTCACTGAGG	CHRM3	ENSG00000133019	-0.517145821274237	[]	[]	-6	hSpCas9	negative selection	2762703
239907569	239907592	1	+	27260157	MKN45	viability	TACAATGTTTCTCGAGCAGCTGG	CHRM3	ENSG00000133019	-0.0132803321714257	[]	[]	0	hSpCas9	negative selection	2765677
239907782	239907805	1	+	27260157	MKN45	viability	GCCTGTGCCGATCTGATTATCGG	CHRM3	ENSG00000133019	0.948565196442079	[]	[]	8	hSpCas9	negative selection	2775455
239908371	239908394	1	+	27260157	MKN45	viability	AGTATGGCCGCTGCCACTTCTGG	CHRM3	ENSG00000133019	0.045368309746116	[]	[]	0	hSpCas9	negative selection	2793901
239908297	239908320	1	-	27260157	MKN45	viability	AGCTTCGAGAACTGCCCGTGGGG	CHRM3	ENSG00000133019	0.529638474985515	[]	[]	6	hSpCas9	negative selection	2793982
239907610	239907633	1	+	27260157	MKN45	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	1.36622446985576	[]	[]	9	hSpCas9	negative selection	2794539
239908415	239908438	1	-	27260157	MKN45	viability	TGGTCCATCTGCTCGGAGCTGGG	CHRM3	ENSG00000133019	1.18498279985035	[]	[]	8	hSpCas9	negative selection	2794589
239907968	239907991	1	-	27260157	MKN45	viability	CGTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.35899725666895	[]	[]	6	hSpCas9	negative selection	2795165
239908344	239908367	1	+	27260157	MKN45	viability	AAAGCATGAAACGCTCCAACAGG	CHRM3	ENSG00000133019	0.417731653275038	[]	[]	6	hSpCas9	negative selection	2796616
239907615	239907638	1	-	27260157	MKN45	viability	ACCTCCCAGAGGGTCATCGGTGG	CHRM3	ENSG00000133019	0.469706876392849	[]	[]	6	hSpCas9	negative selection	2798581
239907957	239907980	1	-	27260157	MKN45	viability	GTACGTGAGCGGCCTCGTGATGG	CHRM3	ENSG00000133019	0.265368944801394	[]	[]	5	hSpCas9	negative selection	2801538
239907888	239907911	1	-	27260157	RKO	viability	ATTGCTGGCTACGTAGTCAATGG	CHRM3	ENSG00000133019	0.670768584527007	[]	[]	7	hSpCas9	negative selection	2805883
239907539	239907562	1	-	27260157	RKO	viability	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	0.159147546673085	[]	[]	0	hSpCas9	negative selection	2806179
239907664	239907687	1	+	27260157	RKO	viability	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	-0.135322589225572	[]	[]	0	hSpCas9	negative selection	2806716
239907696	239907719	1	-	27260157	RKO	viability	TACCAGGATGTTGCCGATGATGG	CHRM3	ENSG00000133019	0.6503645524295	[]	[]	3	hSpCas9	negative selection	2809832
239908229	239908252	1	+	27260157	RKO	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.415942535266588	[]	[]	-6	hSpCas9	negative selection	2811091
239908100	239908123	1	-	27260157	RKO	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.870304267985734	[]	[]	8	hSpCas9	negative selection	2812469
239907783	239907806	1	-	27260157	RKO	viability	CCCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	-0.230821613763528	[]	[]	-1	hSpCas9	negative selection	2836241
239908126	239908149	1	-	27260157	RKO	viability	AAGTAATGGTGGGCTCACTGAGG	CHRM3	ENSG00000133019	-0.226481977985233	[]	[]	-1	hSpCas9	negative selection	2838833
239907569	239907592	1	+	27260157	RKO	viability	TACAATGTTTCTCGAGCAGCTGG	CHRM3	ENSG00000133019	0.441066648191793	[]	[]	2	hSpCas9	negative selection	2841807
239907782	239907805	1	+	27260157	RKO	viability	GCCTGTGCCGATCTGATTATCGG	CHRM3	ENSG00000133019	0.547509690037539	[]	[]	3	hSpCas9	negative selection	2851585
239908371	239908394	1	+	27260157	RKO	viability	AGTATGGCCGCTGCCACTTCTGG	CHRM3	ENSG00000133019	0.105266412814009	[]	[]	0	hSpCas9	negative selection	2870031
239908297	239908320	1	-	27260157	RKO	viability	AGCTTCGAGAACTGCCCGTGGGG	CHRM3	ENSG00000133019	0.664506945023077	[]	[]	3	hSpCas9	negative selection	2870112
239907610	239907633	1	+	27260157	RKO	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	1.42929968187227	[]	[]	9	hSpCas9	negative selection	2870669
239908415	239908438	1	-	27260157	RKO	viability	TGGTCCATCTGCTCGGAGCTGGG	CHRM3	ENSG00000133019	1.44500933171819	[]	[]	9	hSpCas9	negative selection	2870719
239907968	239907991	1	-	27260157	RKO	viability	CGTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	-0.696584425396104	[]	[]	-7	hSpCas9	negative selection	2871295
239908344	239908367	1	+	27260157	RKO	viability	AAAGCATGAAACGCTCCAACAGG	CHRM3	ENSG00000133019	0.726300114151606	[]	[]	8	hSpCas9	negative selection	2872746
239907615	239907638	1	-	27260157	RKO	viability	ACCTCCCAGAGGGTCATCGGTGG	CHRM3	ENSG00000133019	-0.217401315407288	[]	[]	-1	hSpCas9	negative selection	2874711
239907957	239907980	1	-	27260157	RKO	viability	GTACGTGAGCGGCCTCGTGATGG	CHRM3	ENSG00000133019	0.994495201889523	[]	[]	9	hSpCas9	negative selection	2877668
239907888	239907911	1	-	27260157	SF268	viability	ATTGCTGGCTACGTAGTCAATGG	CHRM3	ENSG00000133019	0.785202949160613	[]	[]	8	hSpCas9	negative selection	2882013
239907539	239907562	1	-	27260157	SF268	viability	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	0.136156573850443	[]	[]	0	hSpCas9	negative selection	2882309
239907664	239907687	1	+	27260157	SF268	viability	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	-1.82617099954882	[]	[]	-8	hSpCas9	negative selection	2882846
239907696	239907719	1	-	27260157	SF268	viability	TACCAGGATGTTGCCGATGATGG	CHRM3	ENSG00000133019	0.535296339622153	[]	[]	8	hSpCas9	negative selection	2885962
239908229	239908252	1	+	27260157	SF268	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.747697791320074	[]	[]	-6	hSpCas9	negative selection	2887221
239908100	239908123	1	-	27260157	SF268	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.519635177621966	[]	[]	8	hSpCas9	negative selection	2888599
239907783	239907806	1	-	27260157	SF268	viability	CCCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	-0.13025402444363	[]	[]	-1	hSpCas9	negative selection	2912371
239908126	239908149	1	-	27260157	SF268	viability	AAGTAATGGTGGGCTCACTGAGG	CHRM3	ENSG00000133019	0.0154780465896474	[]	[]	0	hSpCas9	negative selection	2914963
239907569	239907592	1	+	27260157	SF268	viability	TACAATGTTTCTCGAGCAGCTGG	CHRM3	ENSG00000133019	0.189017713936892	[]	[]	0	hSpCas9	negative selection	2917937
239907782	239907805	1	+	27260157	SF268	viability	GCCTGTGCCGATCTGATTATCGG	CHRM3	ENSG00000133019	0.410360788954118	[]	[]	4	hSpCas9	negative selection	2927715
239908371	239908394	1	+	27260157	SF268	viability	AGTATGGCCGCTGCCACTTCTGG	CHRM3	ENSG00000133019	-0.156294662798286	[]	[]	-1	hSpCas9	negative selection	2946161
239908297	239908320	1	-	27260157	SF268	viability	AGCTTCGAGAACTGCCCGTGGGG	CHRM3	ENSG00000133019	0.455134527056944	[]	[]	7	hSpCas9	negative selection	2946242
239907610	239907633	1	+	27260157	SF268	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	1.57125177247625	[]	[]	9	hSpCas9	negative selection	2946799
239908415	239908438	1	-	27260157	SF268	viability	TGGTCCATCTGCTCGGAGCTGGG	CHRM3	ENSG00000133019	1.57904436367806	[]	[]	9	hSpCas9	negative selection	2946849
239907968	239907991	1	-	27260157	SF268	viability	CGTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	-0.191023258373476	[]	[]	-1	hSpCas9	negative selection	2947425
239908344	239908367	1	+	27260157	SF268	viability	AAAGCATGAAACGCTCCAACAGG	CHRM3	ENSG00000133019	0.88107814345688	[]	[]	9	hSpCas9	negative selection	2948876
239907615	239907638	1	-	27260157	SF268	viability	ACCTCCCAGAGGGTCATCGGTGG	CHRM3	ENSG00000133019	0.530212800582667	[]	[]	8	hSpCas9	negative selection	2950841
239907957	239907980	1	-	27260157	SF268	viability	GTACGTGAGCGGCCTCGTGATGG	CHRM3	ENSG00000133019	0.95593423429617	[]	[]	9	hSpCas9	negative selection	2953798
239907642	239907665	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGAAGACCACTTGCCAGACGG	CHRM3	ENSG00000133019	-0.35072846102822397	[3,3]	[3,0]	-5	hSpCas9	positive selection	2979186
239907504	239907527	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.12152164349666156	[3,3]	[3,2]	-2	hSpCas9	positive selection	2979187
239907591	239907614	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCAATTTCTCCTCTCCAGACGG	CHRM3	ENSG00000133019	0.1538638178355925	[4,3]	[2,3]	3	hSpCas9	positive selection	2979188
239907549	239907572	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGCTGCCGAAATGAGTGACGG	CHRM3	ENSG00000133019	0.34743023723332683	[4,4]	[5,5]	7	hSpCas9	positive selection	2979189
239907642	239907665	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGAAGACCACTTGCCAGACGG	CHRM3	ENSG00000133019	0.7414418246474718	[3,3]	[4,3]	9	hSpCas9	positive selection	3047044
239907504	239907527	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	0.2815750672205775	[3,3]	[2,3]	5	hSpCas9	positive selection	3047045
239907591	239907614	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCAATTTCTCCTCTCCAGACGG	CHRM3	ENSG00000133019	0.372842203523463	[4,4]	[2,4]	6	hSpCas9	positive selection	3047046
239907549	239907572	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGCTGCCGAAATGAGTGACGG	CHRM3	ENSG00000133019	0.15508863727119032	[4,4]	[4,3]	2	hSpCas9	positive selection	3047047
239907664	239907687		+	24336571	A375	resistance to PLX after 7 days	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	0.09978084885520877	[11,9]	[12,9]	3	hSpCas9	positive selection	3105541
239907610	239907633		+	24336571	A375	resistance to PLX after 7 days	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-0.1042771615161181	[19,23]	[21,18]	-3	hSpCas9	positive selection	3105542
239909194	239909217		+	24336571	A375	resistance to PLX after 7 days	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.17457690791800862	[10,9]	[9,7]	-5	hSpCas9	positive selection	3105543
239907664	239907687		+	24336571	A375	resistance to PLX after 14 days	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	1.0610977044423973	[10,10]	[7,12]	8	hSpCas9	positive selection	3163334
239907610	239907633		+	24336571	A375	resistance to PLX after 14 days	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	1.0270887251058678	[14,21]	[19,14]	7	hSpCas9	positive selection	3163335
239909194	239909217		+	24336571	A375	resistance to PLX after 14 days	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.08298375743803443	[7,10]	[3,4]	-1	hSpCas9	positive selection	3163336
239907664	239907687		+	24336571	A375	viability after 7 days	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	0.674079856823066	[6]	[11,9]	8	hSpCas9	negative selection	3221127
239907610	239907633		+	24336571	A375	viability after 7 days	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.6762112082036152	[13]	[19,23]	8	hSpCas9	negative selection	3221128
239909194	239909217		+	24336571	A375	viability after 7 days	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.6373294530668829	[16]	[10,9]	-7	hSpCas9	negative selection	3221129
239907664	239907687		+	24336571	A375	viability after 14 days	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	0.6792600617746274	[6]	[10,10]	8	hSpCas9	negative selection	3278920
239907610	239907633		+	24336571	A375	viability after 14 days	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.4268609188476873	[13]	[14,21]	5	hSpCas9	negative selection	3278921
239909194	239909217		+	24336571	A375	viability after 14 days	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.696957402693646	[16]	[7,10]	-7	hSpCas9	negative selection	3278922
239909194	239909217	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.48129105260103655	[123,94]	[0,0]	2	hSpCas9	positive selection	3343105
239908229	239908252	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	1.2333635391574511	[75,53]	[0,0]	5	hSpCas9	positive selection	3343106
239908602	239908625	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.28517463452510394	[175,196]	[0,0]	-2	hSpCas9	positive selection	3343107
239907831	239907854	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	5.13516762893425	[504,504]	[115,115]	9	hSpCas9	positive selection	3362330
239907610	239907633	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-1.147815251690509	[338,338]	[0,0]	-7	hSpCas9	positive selection	3362331
239908005	239908028	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-1.8221585723809801	[540,540]	[0,0]	-9	hSpCas9	positive selection	3362332
239907642	239907665	1	-	26780180	HT29	viability (Avana library 4 designs)	GATGAAGACCACTTGCCAGACGG	CHRM3	ENSG00000133019	-0.552830206863858	[]	[]	-7	hSpCas9	negative selection	3415589
239907504	239907527	1	-	26780180	HT29	viability (Avana library 4 designs)	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	0.354641237659457	[]	[]	1	hSpCas9	negative selection	3415590
239907590	239907613	1	+	26780180	HT29	viability (Avana library 4 designs)	GGCAATTTCTCCTCTCCAGACGG	CHRM3	ENSG00000133019	0.990032247205481	[]	[]	4	hSpCas9	negative selection	3415591
239907549	239907572	1	-	26780180	HT29	viability (Avana library 4 designs)	GTAGCTGCCGAAATGAGTGACGG	CHRM3	ENSG00000133019	-0.118007624568786	[]	[]	-2	hSpCas9	negative selection	3415592
239907549	239907572	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGCTGCCGAAATGAGTGACGG	CHRM3	ENSG00000133019	4.27889844989334	[]	[]	7	hSpCas9	negative selection	3492690
239907590	239907613	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCAATTTCTCCTCTCCAGACGG	CHRM3	ENSG00000133019	-6.44167460017155	[]	[]	-6	hSpCas9	negative selection	3492691
239907642	239907665	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAAGACCACTTGCCAGACGG	CHRM3	ENSG00000133019	-2.3749015757953	[]	[]	-3	hSpCas9	negative selection	3492692
239907504	239907527	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.698715500704933	[]	[]	-1	hSpCas9	negative selection	3492693
239907539	239907562	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	-2.11463323944399	[]	[]	-3	hSpCas9	negative selection	3492694
239907789	239907812	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGACCCCGATAATCAGATCGG	CHRM3	ENSG00000133019	-3.14853581239621	[]	[]	-4	hSpCas9	negative selection	3492695
239907549	239907572	1	-	26780180	A375	viability (Avana lentiGuide)	GTAGCTGCCGAAATGAGTGACGG	CHRM3	ENSG00000133019	-0.617234638122633	[]	[]	-1	hSpCas9	negative selection	3601349
239907590	239907613	1	+	26780180	A375	viability (Avana lentiGuide)	GGCAATTTCTCCTCTCCAGACGG	CHRM3	ENSG00000133019	2.15832339604965	[]	[]	2	hSpCas9	negative selection	3601350
239907642	239907665	1	-	26780180	A375	viability (Avana lentiGuide)	GATGAAGACCACTTGCCAGACGG	CHRM3	ENSG00000133019	-5.32560147549766	[]	[]	-8	hSpCas9	negative selection	3601351
239907504	239907527	1	-	26780180	A375	viability (Avana lentiGuide)	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	7.16568306756852	[]	[]	5	hSpCas9	negative selection	3601352
239907539	239907562	1	-	26780180	A375	viability (Avana lentiGuide)	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	9.36256803799829	[]	[]	6	hSpCas9	negative selection	3601353
239907789	239907812	1	-	26780180	A375	viability (Avana lentiGuide)	AATGACCCCGATAATCAGATCGG	CHRM3	ENSG00000133019	-0.923221311315685	[]	[]	-1	hSpCas9	negative selection	3601354
239907549	239907572	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGCTGCCGAAATGAGTGACGG	CHRM3	ENSG00000133019	0.17317924161109532	[6]	[7,6]	5	hSpCas9	positive selection	3710008
239907590	239907613	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCAATTTCTCCTCTCCAGACGG	CHRM3	ENSG00000133019	-0.5765543226385518	[4]	[4,1]	-7	hSpCas9	positive selection	3710009
239907642	239907665	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAAGACCACTTGCCAGACGG	CHRM3	ENSG00000133019	-1.0438178182421312	[3]	[1,0]	-9	hSpCas9	positive selection	3710010
239907504	239907527	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	0.051873286843599695	[4]	[5,4]	1	hSpCas9	positive selection	3710011
239907539	239907562	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	-0.03499596487488922	[5]	[5,4]	0	hSpCas9	positive selection	3710012
239907789	239907812	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGACCCCGATAATCAGATCGG	CHRM3	ENSG00000133019	-0.11651276240420988	[6]	[4,6]	-2	hSpCas9	positive selection	3710013
239907549	239907572	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGCTGCCGAAATGAGTGACGG	CHRM3	ENSG00000133019	0.28900025066014856	[6]	[7,6]	7	hSpCas9	positive selection	3818615
239907590	239907613	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCAATTTCTCCTCTCCAGACGG	CHRM3	ENSG00000133019	-0.3733139894059613	[5]	[4,2]	-5	hSpCas9	positive selection	3818616
239907642	239907665	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAAGACCACTTGCCAGACGG	CHRM3	ENSG00000133019	-0.03882183886505636	[4]	[5,1]	0	hSpCas9	positive selection	3818617
239907504	239907527	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.17447429810493562	[5]	[3,4]	-2	hSpCas9	positive selection	3818618
239907539	239907562	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAATGAGTGACGGTTCCCGGGGG	CHRM3	ENSG00000133019	-0.2080497435699193	[6]	[4,4]	-3	hSpCas9	positive selection	3818619
239907789	239907812	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGACCCCGATAATCAGATCGG	CHRM3	ENSG00000133019	0.14880032166826795	[7]	[7,6]	3	hSpCas9	positive selection	3818620
239908229	239908252	1	+	26780180	A375	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	1.60241622627585	[]	[]	8	hSpCas9	negative selection	3926678
239908005	239908028	1	-	26780180	A375	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	1.35931623977193	[]	[]	7	hSpCas9	negative selection	3926679
239908602	239908625	1	-	26780180	A375	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	1.30479113672751	[]	[]	7	hSpCas9	negative selection	3926680
239907831	239907854	1	+	26780180	A375	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.401404565947261	[]	[]	1	hSpCas9	negative selection	3926681
239907610	239907633	1	+	26780180	A375	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.617318183767287	[]	[]	2	hSpCas9	negative selection	3926682
239909194	239909217	1	+	26780180	A375	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	1.29693557778621	[]	[]	7	hSpCas9	negative selection	3926683
239908229	239908252	1	+	26780180	HT29	viability (GeCKOv2 library)	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	1.64596419207114	[]	[]	8	hSpCas9	negative selection	4034644
239908005	239908028	1	-	26780180	HT29	viability (GeCKOv2 library)	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.739892024937163	[]	[]	3	hSpCas9	negative selection	4034645
239908602	239908625	1	-	26780180	HT29	viability (GeCKOv2 library)	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	1.13572754175516	[]	[]	5	hSpCas9	negative selection	4034646
239907831	239907854	1	+	26780180	HT29	viability (GeCKOv2 library)	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.672984588806437	[]	[]	2	hSpCas9	negative selection	4034647
239907610	239907633	1	+	26780180	HT29	viability (GeCKOv2 library)	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.624903587698118	[]	[]	2	hSpCas9	negative selection	4034648
239909194	239909217	1	+	26780180	HT29	viability (GeCKOv2 library)	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.856894165297536	[]	[]	3	hSpCas9	negative selection	4034649
239907664	239907687	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	0.8983883300225689	[1]	[2,3]	9	hSpCas9	positive selection	4127647
239907610	239907633	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.4042983082968477	[3]	[2,4]	8	hSpCas9	positive selection	4127648
239909194	239909217	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.09649204414945249	[3]	[2,1]	2	hSpCas9	positive selection	4127649
239907664	239907687	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCTTTCTTAACGGGCATCCTGG	CHRM3	ENSG00000133019	-0.6905900059660646	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4191669
239907610	239907633	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-0.26891577479636547	[4]	[2,1,2,0]	-4	hSpCas9	positive selection	4191670
239909194	239909217	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	1.2559631317128457	[3]	[1,4,2,3]	9	hSpCas9	positive selection	4191671
239909194	239909217	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.11146739354886594	[3]	[2,2]	2	hSpCas9	positive selection	4263249
239908229	239908252	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.3924725162254835	[2]	[1,0]	-7	hSpCas9	positive selection	4263250
239908602	239908625	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.3055057536295225	[3]	[3,3]	6	hSpCas9	positive selection	4263251
239907831	239907854	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.2544315465037754	[3]	[4,3]	5	hSpCas9	positive selection	4327522
239907610	239907633	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.208037317467116	[4]	[3,3]	4	hSpCas9	positive selection	4327523
239908005	239908028	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.02972349597361429	[4]	[3,2]	0	hSpCas9	positive selection	4327524
239907611	239907633	1	+	27760321	OCIAML3	viability	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.3249448345743665	[453,417]	[397,464]	4	hSpCas9	negative selection	4389282
239907783	239907805	1	-	27760321	OCIAML3	viability	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	-0.18604857539797492	[235,220]	[131,189]	-2	hSpCas9	negative selection	4389283
239907832	239907854	1	+	27760321	OCIAML3	viability	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.6033638652634766	[178,163]	[158,261]	7	hSpCas9	negative selection	4389284
239907968	239907990	1	-	27760321	OCIAML3	viability	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.10703880956078976	[528,513]	[424,459]	1	hSpCas9	negative selection	4389285
239908005	239908027	1	-	27760321	OCIAML3	viability	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.1676028411814946	[387,343]	[277,376]	2	hSpCas9	negative selection	4389286
239907611	239907633	1	+	27760321	OCIAML2	viability	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-0.47057418234942894	[453,417]	[241,270]	-5	hSpCas9	negative selection	4472745
239907783	239907805	1	-	27760321	OCIAML2	viability	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.2529776492410991	[235,220]	[181,270]	3	hSpCas9	negative selection	4472746
239907832	239907854	1	+	27760321	OCIAML2	viability	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	-0.3188743612342839	[178,163]	[124,92]	-4	hSpCas9	negative selection	4472747
239907968	239907990	1	-	27760321	OCIAML2	viability	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.027093550209162875	[528,513]	[296,606]	0	hSpCas9	negative selection	4472748
239908005	239908027	1	-	27760321	OCIAML2	viability	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.34647339885083966	[387,343]	[358,397]	5	hSpCas9	negative selection	4472749
239907611	239907633	1	+	27760321	MV411	viability	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.09809029229506118	[453,417]	[219,439]	0	hSpCas9	negative selection	4556208
239907783	239907805	1	-	27760321	MV411	viability	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	-0.13098815354865512	[235,220]	[114,171]	-1	hSpCas9	negative selection	4556209
239907832	239907854	1	+	27760321	MV411	viability	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.5513350278667054	[178,163]	[162,169]	4	hSpCas9	negative selection	4556210
239907968	239907990	1	-	27760321	MV411	viability	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	1.0709143350243582	[528,513]	[572,951]	7	hSpCas9	negative selection	4556211
239908005	239908027	1	-	27760321	MV411	viability	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.3140950584325271	[387,343]	[268,345]	2	hSpCas9	negative selection	4556212
239907611	239907633	1	+	27760321	HL60	viability	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-0.005110602958608245	[453,417]	[399,306]	0	hSpCas9	negative selection	4639671
239907783	239907805	1	-	27760321	HL60	viability	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.8850626271239568	[235,220]	[441,241]	8	hSpCas9	negative selection	4639672
239907832	239907854	1	+	27760321	HL60	viability	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	1.0529220426973742	[178,163]	[325,252]	9	hSpCas9	negative selection	4639673
239907968	239907990	1	-	27760321	HL60	viability	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.3723627100818823	[528,513]	[638,460]	4	hSpCas9	negative selection	4639674
239908005	239908027	1	-	27760321	HL60	viability	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.11867654564825666	[387,343]	[309,338]	1	hSpCas9	negative selection	4639675
239907611	239907633	1	+	27760321	HT1080	viability	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.6442093507637416	[417,325]	[180,286]	3	hSpCas9	negative selection	4723134
239907783	239907805	1	-	27760321	HT1080	viability	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	-0.05028354982657868	[220,172]	[18,137]	0	hSpCas9	negative selection	4723135
239907832	239907854	1	+	27760321	HT1080	viability	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	3.397306501622393	[163,127]	[1019,166]	9	hSpCas9	negative selection	4723136
239907968	239907990	1	-	27760321	HT1080	viability	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.8294070651731684	[513,400]	[267,384]	4	hSpCas9	negative selection	4723137
239908005	239908027	1	-	27760321	HT1080	viability	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.3964580210860764	[343,268]	[87,97]	-2	hSpCas9	negative selection	4723138
239907611	239907633	1	+	27760321	HT29	viability after 7 days	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.10300295177926444	[417,325]	[594,543,415]	1	hSpCas9	negative selection	4806597
239907783	239907805	1	-	27760321	HT29	viability after 7 days	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.3740834631248571	[220,172]	[350,189,442]	6	hSpCas9	negative selection	4806598
239907832	239907854	1	+	27760321	HT29	viability after 7 days	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.025510231547780204	[163,127]	[298,183,107]	0	hSpCas9	negative selection	4806599
239907968	239907990	1	-	27760321	HT29	viability after 7 days	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	-0.10854996648064733	[513,400]	[471,530,619]	-2	hSpCas9	negative selection	4806600
239908005	239908027	1	-	27760321	HT29	viability after 7 days	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.18551758011221842	[343,268]	[476,420,449]	3	hSpCas9	negative selection	4806601
239907611	239907633	1	+	27760321	HT29	viability after 25 days	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.47702541051429787	[417,325]	[817,435,495]	5	hSpCas9	negative selection	4890060
239907783	239907805	1	-	27760321	HT29	viability after 25 days	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.09378695441197815	[220,172]	[181,208,343]	0	hSpCas9	negative selection	4890061
239907832	239907854	1	+	27760321	HT29	viability after 25 days	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.3249801167049734	[163,127]	[316,161,132]	3	hSpCas9	negative selection	4890062
239907968	239907990	1	-	27760321	HT29	viability after 25 days	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.5267999063501314	[513,400]	[635,738,906]	6	hSpCas9	negative selection	4890063
239908005	239908027	1	-	27760321	HT29	viability after 25 days	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	1.1456560247201517	[343,268]	[730,706,901]	9	hSpCas9	negative selection	4890064
239907611	239907633	1	+	27760321	HT29	viability after 22 days	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.3821813395297152	[417,325]	[522,638,519]	4	hSpCas9	negative selection	4973523
239907783	239907805	1	-	27760321	HT29	viability after 22 days	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.23234369803808363	[220,172]	[193,106,505]	2	hSpCas9	negative selection	4973524
239907832	239907854	1	+	27760321	HT29	viability after 22 days	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.5173190000182797	[163,127]	[316,235,168]	6	hSpCas9	negative selection	4973525
239907968	239907990	1	-	27760321	HT29	viability after 22 days	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.5042252252702888	[513,400]	[677,755,818]	5	hSpCas9	negative selection	4973526
239908005	239908027	1	-	27760321	HT29	viability after 22 days	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	1.1698391132445336	[343,268]	[927,589,870]	9	hSpCas9	negative selection	4973527
239907611	239907633	1	+	27760321	HT29	viability after 19 days	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.7671390128214152	[417,325]	[709,651,804]	7	hSpCas9	negative selection	5056986
239907783	239907805	1	-	27760321	HT29	viability after 19 days	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.35752146470373813	[220,172]	[266,235,357]	3	hSpCas9	negative selection	5056987
239907832	239907854	1	+	27760321	HT29	viability after 19 days	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.48192176578117285	[163,127]	[398,223,98]	5	hSpCas9	negative selection	5056988
239907968	239907990	1	-	27760321	HT29	viability after 19 days	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	-0.08362360798999863	[513,400]	[522,547,415]	-1	hSpCas9	negative selection	5056989
239908005	239908027	1	-	27760321	HT29	viability after 19 days	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.9650348370191573	[343,268]	[865,476,726]	8	hSpCas9	negative selection	5056990
239907611	239907633	1	+	27760321	HT29	viability after 16 days	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.21849804788185712	[417,325]	[585,492,382]	2	hSpCas9	negative selection	5140449
239907783	239907805	1	-	27760321	HT29	viability after 16 days	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.7759272656852926	[220,172]	[345,199,587]	8	hSpCas9	negative selection	5140450
239907832	239907854	1	+	27760321	HT29	viability after 16 days	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	-0.007237413498371037	[163,127]	[302,155,41]	0	hSpCas9	negative selection	5140451
239907968	239907990	1	-	27760321	HT29	viability after 16 days	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.12692387888710316	[513,400]	[768,232,702]	1	hSpCas9	negative selection	5140452
239908005	239908027	1	-	27760321	HT29	viability after 16 days	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.9104151992562027	[343,268]	[699,719,516]	9	hSpCas9	negative selection	5140453
239907611	239907633	1	+	27760321	HT29	viability after 13 days	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.14249634156904611	[417,325]	[611,380,437]	1	hSpCas9	negative selection	5223912
239907783	239907805	1	-	27760321	HT29	viability after 13 days	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.39612241008903526	[220,172]	[303,103,482]	5	hSpCas9	negative selection	5223913
239907832	239907854	1	+	27760321	HT29	viability after 13 days	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.3845697114558656	[163,127]	[211,360,97]	5	hSpCas9	negative selection	5223914
239907968	239907990	1	-	27760321	HT29	viability after 13 days	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	0.22418061235205983	[513,400]	[466,719,669]	2	hSpCas9	negative selection	5223915
239908005	239908027	1	-	27760321	HT29	viability after 13 days	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.4799935757619638	[343,268]	[541,555,395]	6	hSpCas9	negative selection	5223916
239907611	239907633	1	+	27760321	HT29	viability after 10 days	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-0.1183576073313033	[417,325]	[337,537,410]	-1	hSpCas9	negative selection	5307375
239907783	239907805	1	-	27760321	HT29	viability after 10 days	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.5315672349166484	[220,172]	[236,252,568]	7	hSpCas9	negative selection	5307376
239907832	239907854	1	+	27760321	HT29	viability after 10 days	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.645735978149367	[163,127]	[421,212,219]	8	hSpCas9	negative selection	5307377
239907968	239907990	1	-	27760321	HT29	viability after 10 days	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	-0.0843500353053368	[513,400]	[522,581,512]	-1	hSpCas9	negative selection	5307378
239908005	239908027	1	-	27760321	HT29	viability after 10 days	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.5928660028389738	[343,268]	[398,583,744]	7	hSpCas9	negative selection	5307379
239907611	239907633	1	+	27760321	MOLM13	viability	GGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	-0.05970365800477744	[453,417]	[262,212]	0	hSpCas9	negative selection	5390838
239907783	239907805	1	-	27760321	MOLM13	viability	CCGATAATCAGATCGGCACAGG	CHRM3	ENSG00000133019	0.7826630471425398	[235,220]	[323,134]	5	hSpCas9	negative selection	5390839
239907832	239907854	1	+	27760321	MOLM13	viability	CTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	-0.5173139827756381	[178,163]	[126,16]	-3	hSpCas9	negative selection	5390840
239907968	239907990	1	-	27760321	MOLM13	viability	GTTTGGCTCGGTACGTGAGCGG	CHRM3	ENSG00000133019	1.4395875434173906	[528,513]	[829,773]	8	hSpCas9	negative selection	5390841
239908005	239908027	1	-	27760321	MOLM13	viability	GCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	1.4040447601325736	[387,343]	[436,637]	8	hSpCas9	negative selection	5390842
239909194	239909217	1	+	27260156	BXPC3	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.11635693036583486	[477]	[432,522,579,654]	2	hSpCas9	negative selection	5535709
239908229	239908252	1	+	27260156	BXPC3	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.09941093384256272	[408]	[374,340,506,375]	-2	hSpCas9	negative selection	5535710
239908602	239908625	1	-	27260156	BXPC3	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.1326166039994109	[720]	[693,683,985,980]	3	hSpCas9	negative selection	5535711
239907831	239907854	1	+	27260156	BXPC3	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.19250636237333263	[926]	[1019,1127,962,1346]	4	hSpCas9	negative selection	5599982
239907610	239907633	1	+	27260156	BXPC3	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.21009192743070804	[1046]	[1218,1179,1263,1422]	4	hSpCas9	negative selection	5599983
239908005	239908028	1	-	27260156	BXPC3	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.0038745496634469134	[1343]	[1403,1199,1418,1610]	0	hSpCas9	negative selection	5599984
239909194	239909217	1	+	27260156	A673	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.12801204090439305	[477]	[681,585,663,579]	3	hSpCas9	negative selection	5656960
239908229	239908252	1	+	27260156	A673	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.03311590054583982	[408]	[535,472,449,465]	-1	hSpCas9	negative selection	5656961
239908602	239908625	1	-	27260156	A673	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.015170248462911817	[720]	[912,970,659,887]	0	hSpCas9	negative selection	5656962
239907831	239907854	1	+	27260156	A673	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.15646689977499706	[926]	[1414,982,1328,1259]	4	hSpCas9	negative selection	5721233
239907610	239907633	1	+	27260156	A673	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.24944540577992824	[1046]	[1759,1309,1383,1560]	6	hSpCas9	negative selection	5721234
239908005	239908028	1	-	27260156	A673	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.024449371877544923	[1343]	[1832,1321,1539,1689]	0	hSpCas9	negative selection	5721235
239909194	239909217	1	+	27260156	A375	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.25853440754501994	[477]	[591,335,667,274]	-4	hSpCas9	negative selection	5778211
239908229	239908252	1	+	27260156	A375	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.37573778900929156	[408]	[591,875,781,300]	5	hSpCas9	negative selection	5778212
239908602	239908625	1	-	27260156	A375	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.07943602747604928	[720]	[866,932,668,741]	-1	hSpCas9	negative selection	5778213
239907831	239907854	1	+	27260156	A375	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.2226622099410388	[926]	[1073,1389,1374,1229]	3	hSpCas9	negative selection	5842484
239907610	239907633	1	+	27260156	A375	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.38065883924578414	[1046]	[1572,1634,1437,1707]	5	hSpCas9	negative selection	5842485
239908005	239908028	1	-	27260156	A375	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.35133999183338793	[1343]	[954,1594,1288,1137]	-5	hSpCas9	negative selection	5842486
239909194	239909217	1	+	27260156	COLO741	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.06153125376847022	[477]	[629,502,766]	1	hSpCas9	negative selection	5899462
239908229	239908252	1	+	27260156	COLO741	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.03269887389723111	[408]	[638,460,446]	0	hSpCas9	negative selection	5899463
239908602	239908625	1	-	27260156	COLO741	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.1372506142160328	[720]	[975,646,894]	-3	hSpCas9	negative selection	5899464
239907831	239907854	1	+	27260156	COLO741	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.1129141389289775	[926]	[1449,1363,1056]	2	hSpCas9	negative selection	5963735
239907610	239907633	1	+	27260156	COLO741	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.2950680108164203	[1046]	[1794,1620,1525]	6	hSpCas9	negative selection	5963736
239908005	239908028	1	-	27260156	COLO741	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.34778169975441875	[1343]	[1381,1262,1398]	-6	hSpCas9	negative selection	5963737
239909194	239909217	1	+	27260156	CAL120	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.3017751657938854	[477]	[523,520,409]	-4	hSpCas9	negative selection	6020713
239908229	239908252	1	+	27260156	CAL120	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.5118258499950685	[408]	[748,409,1015]	7	hSpCas9	negative selection	6020714
239908602	239908625	1	-	27260156	CAL120	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.046148792902258706	[720]	[903,794,911]	0	hSpCas9	negative selection	6020715
239907831	239907854	1	+	27260156	CAL120	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.19435953072149348	[926]	[1432,1100,1439]	3	hSpCas9	negative selection	6084986
239907610	239907633	1	+	27260156	CAL120	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.5710277098239982	[1046]	[2054,2126,1646]	8	hSpCas9	negative selection	6084987
239908005	239908028	1	-	27260156	CAL120	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.6308097227082176	[1343]	[1226,1069,966]	-7	hSpCas9	negative selection	6084988
239909194	239909217	1	+	27260156	CADOES1	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.20685392507792083	[477]	[460,340,364,372]	-4	hSpCas9	negative selection	6141964
239908229	239908252	1	+	27260156	CADOES1	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.13946540002244992	[408]	[416,485,332,440]	2	hSpCas9	negative selection	6141965
239908602	239908625	1	-	27260156	CADOES1	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.3261296274546275	[720]	[460,421,606,653]	-5	hSpCas9	negative selection	6141966
239907831	239907854	1	+	27260156	CADOES1	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.2182751262766981	[926]	[1141,1069,918,875]	3	hSpCas9	negative selection	6206237
239907610	239907633	1	+	27260156	CADOES1	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.20377743860486408	[1046]	[1285,925,1257,1010]	3	hSpCas9	negative selection	6206238
239908005	239908028	1	-	27260156	CADOES1	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.4346389892379505	[1343]	[924,915,840,1020]	-6	hSpCas9	negative selection	6206239
239909194	239909217	1	+	27260156	EWS502	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.01862355891091523	[477]	[630,394,448,567]	0	hSpCas9	negative selection	6263215
239908229	239908252	1	+	27260156	EWS502	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.0036000513406821977	[408]	[484,483,333,421]	0	hSpCas9	negative selection	6263216
239908602	239908625	1	-	27260156	EWS502	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.05371025517479411	[720]	[823,828,732,773]	0	hSpCas9	negative selection	6263217
239907831	239907854	1	+	27260156	EWS502	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.46227008267491854	[926]	[1252,1460,1188,1519]	7	hSpCas9	negative selection	6327488
239907610	239907633	1	+	27260156	EWS502	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.44766520636673235	[1046]	[1464,1493,1407,1694]	7	hSpCas9	negative selection	6327489
239908005	239908028	1	-	27260156	EWS502	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.12869813674103736	[1343]	[982,1263,1537,1473]	-2	hSpCas9	negative selection	6327490
239909194	239909217	1	+	27260156	EW8	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.07010717180443232	[477]	[376,331,589,291]	1	hSpCas9	negative selection	6384466
239908229	239908252	1	+	27260156	EW8	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.13201949285870385	[408]	[334,418,197,278]	-3	hSpCas9	negative selection	6384467
239908602	239908625	1	-	27260156	EW8	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.13073538312693833	[720]	[983,654,405,589]	2	hSpCas9	negative selection	6384468
239907831	239907854	1	+	27260156	EW8	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.18172814865794062	[926]	[1126,832,598,919]	3	hSpCas9	negative selection	6448739
239907610	239907633	1	+	27260156	EW8	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.5160259366899622	[1046]	[1573,1271,997,1082]	8	hSpCas9	negative selection	6448740
239908005	239908028	1	-	27260156	EW8	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.012849410058316524	[1343]	[1363,1116,949,937]	0	hSpCas9	negative selection	6448741
239909194	239909217	1	+	27260156	CORL105	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.0767392720274934	[477]	[404,519,620,585]	-1	hSpCas9	negative selection	6505717
239908229	239908252	1	+	27260156	CORL105	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.17162547031917183	[408]	[673,559,558,371]	3	hSpCas9	negative selection	6505718
239908602	239908625	1	-	27260156	CORL105	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.2415803863273962	[720]	[785,696,835,558]	-4	hSpCas9	negative selection	6505719
239907831	239907854	1	+	27260156	CORL105	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.03279600548004835	[926]	[1127,946,1256,1134]	0	hSpCas9	negative selection	6569990
239907610	239907633	1	+	27260156	CORL105	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.3223690531690706	[1046]	[1645,1448,1666,1394]	6	hSpCas9	negative selection	6569991
239908005	239908028	1	-	27260156	CORL105	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.20132688128879073	[1343]	[1346,1203,1667,1303]	-4	hSpCas9	negative selection	6569992
239909194	239909217	1	+	27260156	HS294T	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.1888451582209247	[477]	[126,164,163,201]	-3	hSpCas9	negative selection	6626968
239908229	239908252	1	+	27260156	HS294T	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.48108590850458516	[408]	[171,166,137,449]	6	hSpCas9	negative selection	6626969
239908602	239908625	1	-	27260156	HS294T	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.08607987891749491	[720]	[255,239,373,322]	1	hSpCas9	negative selection	6626970
239907831	239907854	1	+	27260156	HS294T	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.4429754762601309	[926]	[288,384,459,905]	6	hSpCas9	negative selection	6691241
239907610	239907633	1	+	27260156	HS294T	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.8487846514206048	[1046]	[798,439,773,938]	9	hSpCas9	negative selection	6691242
239908005	239908028	1	-	27260156	HS294T	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.0972043255967503	[1343]	[539,532,474,699]	1	hSpCas9	negative selection	6691243
239909194	239909217	1	+	27260156	HCC44	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.037425332746970845	[477]	[601,541,509,452]	0	hSpCas9	negative selection	6748219
239908229	239908252	1	+	27260156	HCC44	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.2480357043695517	[408]	[646,542,551,463]	4	hSpCas9	negative selection	6748220
239908602	239908625	1	-	27260156	HCC44	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.2245170235228635	[720]	[1147,989,786,864]	3	hSpCas9	negative selection	6748221
239907831	239907854	1	+	27260156	HCC44	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.599943082569392	[926]	[2060,1427,1209,1642]	8	hSpCas9	negative selection	6812492
239907610	239907633	1	+	27260156	HCC44	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.36692510682548574	[1046]	[1559,1480,2033,1130]	6	hSpCas9	negative selection	6812493
239908005	239908028	1	-	27260156	HCC44	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.09941877708574043	[1343]	[1405,1470,1644,1971]	1	hSpCas9	negative selection	6812494
239909194	239909217	1	+	27260156	G402	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.14473024640359008	[477]	[458,579,859,646]	1	hSpCas9	negative selection	6869470
239908229	239908252	1	+	27260156	G402	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.012620938218454197	[408]	[518,664,261,541]	0	hSpCas9	negative selection	6869471
239908602	239908625	1	-	27260156	G402	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.07206907600596191	[720]	[1056,667,903,741]	-1	hSpCas9	negative selection	6869472
239907831	239907854	1	+	27260156	G402	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.7915231467482212	[926]	[1931,2408,1624,1883]	8	hSpCas9	negative selection	6933743
239907610	239907633	1	+	27260156	G402	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.47524563472045656	[1046]	[2154,1860,1560,1588]	6	hSpCas9	negative selection	6933744
239908005	239908028	1	-	27260156	G402	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.14748967677212765	[1343]	[1512,1706,1415,1306]	-2	hSpCas9	negative selection	6933745
239909194	239909217	1	+	27260156	L33	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.023757609902444257	[477]	[573,185,309,420]	0	hSpCas9	negative selection	6990721
239908229	239908252	1	+	27260156	L33	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.008875639291437504	[408]	[435,179,287,292]	0	hSpCas9	negative selection	6990722
239908602	239908625	1	-	27260156	L33	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.11301827054236124	[720]	[837,317,530,659]	2	hSpCas9	negative selection	6990723
239907831	239907854	1	+	27260156	L33	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	-0.009030951102083074	[926]	[911,364,565,980]	0	hSpCas9	negative selection	7054994
239907610	239907633	1	+	27260156	L33	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.238105480574353	[1046]	[1169,552,814,1125]	5	hSpCas9	negative selection	7054995
239908005	239908028	1	-	27260156	L33	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.13740900252745125	[1343]	[1131,408,900,1325]	-3	hSpCas9	negative selection	7054996
239909194	239909217	1	+	27260156	K562	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.12896810162954253	[477]	[525,775,222,361]	1	hSpCas9	negative selection	7111972
239908229	239908252	1	+	27260156	K562	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.33519300573984123	[408]	[606,587,368,302]	4	hSpCas9	negative selection	7111973
239908602	239908625	1	-	27260156	K562	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.12871339407537907	[720]	[657,627,839,665]	1	hSpCas9	negative selection	7111974
239907831	239907854	1	+	27260156	K562	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.23897977902960832	[926]	[886,704,885,1336]	3	hSpCas9	negative selection	7176245
239907610	239907633	1	+	27260156	K562	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.5914209688734418	[1046]	[1470,1273,1475,1374]	7	hSpCas9	negative selection	7176246
239908005	239908028	1	-	27260156	K562	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.16606606800049684	[1343]	[1475,939,1079,808]	-2	hSpCas9	negative selection	7176247
239909194	239909217	1	+	27260156	HT29	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.23918807716055424	[477]	[656,466,475,388]	-5	hSpCas9	negative selection	7233223
239908229	239908252	1	+	27260156	HT29	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.0523613000647446	[408]	[536,699,296,538]	1	hSpCas9	negative selection	7233224
239908602	239908625	1	-	27260156	HT29	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.08250912447497527	[720]	[937,955,697,742]	-2	hSpCas9	negative selection	7233225
239907831	239907854	1	+	27260156	HT29	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.2539971163090998	[926]	[1398,1480,1458,1075]	5	hSpCas9	negative selection	7297496
239907610	239907633	1	+	27260156	HT29	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.2695565306176704	[1046]	[1785,1829,1303,1281]	5	hSpCas9	negative selection	7297497
239908005	239908028	1	-	27260156	HT29	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.12596658945242512	[1343]	[1664,1558,1570,1233]	-3	hSpCas9	negative selection	7297498
239909194	239909217	1	+	27260156	MHHES1	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.036556011782321506	[477]	[726,482,419,485]	0	hSpCas9	negative selection	7354474
239908229	239908252	1	+	27260156	MHHES1	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.14661639943260374	[408]	[559,474,367,301]	-3	hSpCas9	negative selection	7354475
239908602	239908625	1	-	27260156	MHHES1	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.008860983250006393	[720]	[942,711,688,858]	0	hSpCas9	negative selection	7354476
239907831	239907854	1	+	27260156	MHHES1	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.4136892568416354	[926]	[1633,1553,1440,1032]	7	hSpCas9	negative selection	7418747
239907610	239907633	1	+	27260156	MHHES1	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.23631541402512934	[1046]	[1545,1514,1504,1066]	4	hSpCas9	negative selection	7418748
239908005	239908028	1	-	27260156	MHHES1	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.3797760621607218	[1343]	[1320,1139,1204,1012]	-6	hSpCas9	negative selection	7418749
239909194	239909217	1	+	27260156	MEWO	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.057272181573386156	[477]	[681,424,330]	1	hSpCas9	negative selection	7475725
239908229	239908252	1	+	27260156	MEWO	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.03460752355749322	[408]	[368,447,353]	0	hSpCas9	negative selection	7475726
239908602	239908625	1	-	27260156	MEWO	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.20220527314123615	[720]	[951,571,838]	4	hSpCas9	negative selection	7475727
239907831	239907854	1	+	27260156	MEWO	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.28288701168287156	[926]	[1209,1092,891]	6	hSpCas9	negative selection	7539998
239907610	239907633	1	+	27260156	MEWO	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.05262549614059098	[1046]	[1306,797,999]	1	hSpCas9	negative selection	7539999
239908005	239908028	1	-	27260156	MEWO	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.2693213351309873	[1343]	[1196,913,1048]	-5	hSpCas9	negative selection	7540000
239909194	239909217	1	+	27260156	LNCAPCLONEFGC	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.3526847589197358	[477]	[269,430,423,238]	-5	hSpCas9	negative selection	7596976
239908229	239908252	1	+	27260156	LNCAPCLONEFGC	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.33828701342388146	[408]	[469,377,540,500]	5	hSpCas9	negative selection	7596977
239908602	239908625	1	-	27260156	LNCAPCLONEFGC	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.22639798012410733	[720]	[488,535,628,591]	-4	hSpCas9	negative selection	7596978
239907831	239907854	1	+	27260156	LNCAPCLONEFGC	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.3352688824216902	[926]	[969,1171,1212,898]	5	hSpCas9	negative selection	7661249
239907610	239907633	1	+	27260156	LNCAPCLONEFGC	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.447572795762071	[1046]	[1252,1112,1471,1373]	7	hSpCas9	negative selection	7661250
239908005	239908028	1	-	27260156	LNCAPCLONEFGC	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.20678224580300553	[1343]	[1310,811,1189,936]	-3	hSpCas9	negative selection	7661251
239909194	239909217	1	+	27260156	PANC0327	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.07151504553581961	[477]	[409,302,440,645]	1	hSpCas9	negative selection	7718227
239908229	239908252	1	+	27260156	PANC0327	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.3054026941565154	[408]	[337,327,211,296]	-4	hSpCas9	negative selection	7718228
239908602	239908625	1	-	27260156	PANC0327	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.1817950612876773	[720]	[572,491,390,811]	-3	hSpCas9	negative selection	7718229
239907831	239907854	1	+	27260156	PANC0327	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.2236664450824083	[926]	[1021,756,888,1208]	3	hSpCas9	negative selection	7782500
239907610	239907633	1	+	27260156	PANC0327	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.4526183445886145	[1046]	[1147,955,1616,1400]	6	hSpCas9	negative selection	7782501
239908005	239908028	1	-	27260156	PANC0327	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.04363281928267959	[1343]	[976,1125,1533,1277]	0	hSpCas9	negative selection	7782502
239909194	239909217	1	+	27260156	NCIH2009	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.3409457661159007	[477]	[670,490,447]	-4	hSpCas9	negative selection	7839478
239908229	239908252	1	+	27260156	NCIH2009	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.4413184681152611	[408]	[934,714,708]	6	hSpCas9	negative selection	7839479
239908602	239908625	1	-	27260156	NCIH2009	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.3247780471124131	[720]	[1350,1456,988]	4	hSpCas9	negative selection	7839480
239907831	239907854	1	+	27260156	NCIH2009	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.18113911326603904	[926]	[1369,1376,1637]	2	hSpCas9	negative selection	7903751
239907610	239907633	1	+	27260156	NCIH2009	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.46213602861017167	[1046]	[2260,1829,2002]	6	hSpCas9	negative selection	7903752
239908005	239908028	1	-	27260156	NCIH2009	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.19709850092568804	[1343]	[1904,1360,1702]	-3	hSpCas9	negative selection	7903753
239909194	239909217	1	+	27260156	NCIH1373	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.1978964640288317	[477]	[286,595,286,175]	-2	hSpCas9	negative selection	7960729
239908229	239908252	1	+	27260156	NCIH1373	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.6740188254377513	[408]	[827,509,706,243]	6	hSpCas9	negative selection	7960730
239908602	239908625	1	-	27260156	NCIH1373	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.1903549177313585	[720]	[1384,666,994,189]	1	hSpCas9	negative selection	7960731
239907831	239907854	1	+	27260156	NCIH1373	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.5331373869487087	[926]	[1568,1351,1056,551]	5	hSpCas9	negative selection	8025002
239907610	239907633	1	+	27260156	NCIH1373	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.7497601110579624	[1046]	[1785,1930,2294,480]	7	hSpCas9	negative selection	8025003
239908005	239908028	1	-	27260156	NCIH1373	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.4524192982955211	[1343]	[1017,1269,959,294]	-4	hSpCas9	negative selection	8025004
239909194	239909217	1	+	27260156	PATU8902	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.2768177909989704	[477]	[498,763,245,793]	-3	hSpCas9	negative selection	8081980
239908229	239908252	1	+	27260156	PATU8902	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.6314060235555268	[408]	[711,917,669,1333]	6	hSpCas9	negative selection	8081981
239908602	239908625	1	-	27260156	PATU8902	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.09716675622552484	[720]	[785,1058,751,1236]	-1	hSpCas9	negative selection	8081982
239907831	239907854	1	+	27260156	PATU8902	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.2704528825734328	[926]	[1265,2365,1103,1610]	2	hSpCas9	negative selection	8146253
239907610	239907633	1	+	27260156	PATU8902	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.6665357193998882	[1046]	[2234,2832,2026,2208]	7	hSpCas9	negative selection	8146254
239908005	239908028	1	-	27260156	PATU8902	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.1509688617991718	[1343]	[1924,1305,1541,2030]	-1	hSpCas9	negative selection	8146255
239909194	239909217	1	+	27260156	PANC1	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	0.07981005842136105	[477]	[367,579,414,401]	1	hSpCas9	negative selection	8203231
239908229	239908252	1	+	27260156	PANC1	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.16976685850464796	[408]	[306,433,305,234]	-3	hSpCas9	negative selection	8203232
239908602	239908625	1	-	27260156	PANC1	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.061386283882112314	[720]	[627,638,752,566]	0	hSpCas9	negative selection	8203233
239907831	239907854	1	+	27260156	PANC1	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.35053321014547645	[926]	[954,1088,1033,986]	5	hSpCas9	negative selection	8267504
239907610	239907633	1	+	27260156	PANC1	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.1993002208288539	[1046]	[928,1465,1026,817]	3	hSpCas9	negative selection	8267505
239908005	239908028	1	-	27260156	PANC1	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.02381877867178739	[1343]	[938,1482,1265,1072]	0	hSpCas9	negative selection	8267506
239909194	239909217	1	+	27260156	PANC0813	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.3435739649404175	[477]	[571,344,555,315]	-5	hSpCas9	negative selection	8324482
239908229	239908252	1	+	27260156	PANC0813	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.29222825565978483	[408]	[594,632,663,467]	5	hSpCas9	negative selection	8324483
239908602	239908625	1	-	27260156	PANC0813	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.07035260022822942	[720]	[798,845,948,949]	1	hSpCas9	negative selection	8324484
239907831	239907854	1	+	27260156	PANC0813	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.20817085100658372	[926]	[1212,1513,1241,1066]	3	hSpCas9	negative selection	8388755
239907610	239907633	1	+	27260156	PANC0813	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.3624032746584538	[1046]	[1344,1489,1828,1633]	6	hSpCas9	negative selection	8388756
239908005	239908028	1	-	27260156	PANC0813	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	0.113350806764966	[1343]	[1668,1507,1994,1656]	1	hSpCas9	negative selection	8388757
239909194	239909217	1	+	27260156	RDES	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.30105145137655703	[477]	[456,322,435,583]	-5	hSpCas9	negative selection	8445733
239908229	239908252	1	+	27260156	RDES	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.15234963334836785	[408]	[439,490,641,527]	2	hSpCas9	negative selection	8445734
239908602	239908625	1	-	27260156	RDES	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.1618934556622873	[720]	[678,492,872,974]	-3	hSpCas9	negative selection	8445735
239907831	239907854	1	+	27260156	RDES	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.3339372951069991	[926]	[1019,1334,1627,1449]	5	hSpCas9	negative selection	8510006
239907610	239907633	1	+	27260156	RDES	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.435033971741122	[1046]	[1200,1443,1835,2187]	7	hSpCas9	negative selection	8510007
239908005	239908028	1	-	27260156	RDES	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.5429385571924061	[1343]	[902,837,1099,1493]	-7	hSpCas9	negative selection	8510008
239909194	239909217	1	+	27260156	PC3	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.743811593978117	[477]	[220,220,510,270]	-9	hSpCas9	negative selection	8566984
239908229	239908252	1	+	27260156	PC3	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.010802050400555346	[408]	[199,388,999,316]	0	hSpCas9	negative selection	8566985
239908602	239908625	1	-	27260156	PC3	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.15643011620122105	[720]	[365,727,1108,614]	-4	hSpCas9	negative selection	8566986
239907831	239907854	1	+	27260156	PC3	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.012949136386718352	[926]	[548,909,1809,883]	0	hSpCas9	negative selection	8631257
239907610	239907633	1	+	27260156	PC3	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.16354405843959863	[1046]	[853,972,2205,1061]	3	hSpCas9	negative selection	8631258
239908005	239908028	1	-	27260156	PC3	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.6844475620198609	[1343]	[501,977,1452,693]	-9	hSpCas9	negative selection	8631259
239909194	239909217	1	+	27260156	PATU8988T	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.13053759505861925	[477]	[785,214,293,370]	-2	hSpCas9	negative selection	8688235
239908229	239908252	1	+	27260156	PATU8988T	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.09123258505796353	[408]	[470,374,273,573]	1	hSpCas9	negative selection	8688236
239908602	239908625	1	-	27260156	PATU8988T	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.3025500553352237	[720]	[319,711,847,373]	-5	hSpCas9	negative selection	8688237
239907831	239907854	1	+	27260156	PATU8988T	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.15060581287844055	[926]	[755,1065,1188,967]	2	hSpCas9	negative selection	8752508
239907610	239907633	1	+	27260156	PATU8988T	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.16716574916764282	[1046]	[1256,1068,1040,1174]	3	hSpCas9	negative selection	8752509
239908005	239908028	1	-	27260156	PATU8988T	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.053317724988030335	[1343]	[1514,1105,1114,1258]	-1	hSpCas9	negative selection	8752510
239909194	239909217	1	+	27260156	T47D	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.2472025496324513	[477]	[426,359,573,524]	-5	hSpCas9	negative selection	8809486
239908229	239908252	1	+	27260156	T47D	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.007073667019870389	[408]	[507,433,400,560]	0	hSpCas9	negative selection	8809487
239908602	239908625	1	-	27260156	T47D	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.2234469531968435	[720]	[795,652,667,768]	-5	hSpCas9	negative selection	8809488
239907831	239907854	1	+	27260156	T47D	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.20522044443699616	[926]	[1198,1179,1284,1322]	4	hSpCas9	negative selection	8873759
239907610	239907633	1	+	27260156	T47D	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.24338504386889492	[1046]	[1459,1337,1516,1468]	5	hSpCas9	negative selection	8873760
239908005	239908028	1	-	27260156	T47D	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.4014314282990339	[1343]	[1364,1043,1196,1146]	-7	hSpCas9	negative selection	8873761
239909194	239909217	1	+	27260156	SU8686	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.1507562005675372	[477]	[442,281,445,574]	-3	hSpCas9	negative selection	8930737
239908229	239908252	1	+	27260156	SU8686	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.1663600674169252	[408]	[293,406,580,583]	3	hSpCas9	negative selection	8930738
239908602	239908625	1	-	27260156	SU8686	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.03782292380615959	[720]	[611,733,788,824]	0	hSpCas9	negative selection	8930739
239907831	239907854	1	+	27260156	SU8686	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.34933095629273037	[926]	[1072,1009,937,1777]	6	hSpCas9	negative selection	8995010
239907610	239907633	1	+	27260156	SU8686	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.3906422799304887	[1046]	[1340,1135,1306,1740]	6	hSpCas9	negative selection	8995011
239908005	239908028	1	-	27260156	SU8686	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.06725713704617964	[1343]	[939,1163,1291,1823]	-1	hSpCas9	negative selection	8995012
239909194	239909217	1	+	27260156	SKES1	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.3237060945893507	[477]	[402,311,447,353]	-6	hSpCas9	negative selection	9051988
239908229	239908252	1	+	27260156	SKES1	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.21998900479660646	[408]	[639,479,448,363]	5	hSpCas9	negative selection	9051989
239908602	239908625	1	-	27260156	SKES1	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.06497639322258919	[720]	[971,764,569,507]	-1	hSpCas9	negative selection	9051990
239907831	239907854	1	+	27260156	SKES1	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.27058057084226783	[926]	[1174,1209,1089,1007]	6	hSpCas9	negative selection	9116261
239907610	239907633	1	+	27260156	SKES1	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.3899506417509184	[1046]	[1626,1325,1441,1123]	7	hSpCas9	negative selection	9116262
239908005	239908028	1	-	27260156	SKES1	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.10131466931548982	[1343]	[1346,1494,1243,975]	-2	hSpCas9	negative selection	9116263
239909194	239909217	1	+	27260156	TOV112D	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.010969251899355747	[477]	[643,575,289,429]	0	hSpCas9	negative selection	9173239
239908229	239908252	1	+	27260156	TOV112D	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.21988655754330805	[408]	[455,353,861,210]	4	hSpCas9	negative selection	9173240
239908602	239908625	1	-	27260156	TOV112D	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.025321426812618397	[720]	[629,894,605,743]	0	hSpCas9	negative selection	9173241
239907831	239907854	1	+	27260156	TOV112D	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.15185027737140533	[926]	[1174,975,915,1054]	3	hSpCas9	negative selection	9237512
239907610	239907633	1	+	27260156	TOV112D	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.27674825386692703	[1046]	[1556,1230,1114,1192]	5	hSpCas9	negative selection	9237513
239908005	239908028	1	-	27260156	TOV112D	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.06974997576803954	[1343]	[1255,1625,1394,942]	-1	hSpCas9	negative selection	9237514
239909194	239909217	1	+	27260156	TC71	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.0917023040784343	[477]	[445,472,469,538]	-2	hSpCas9	negative selection	9294490
239908229	239908252	1	+	27260156	TC71	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	-0.0966349359303258	[408]	[396,389,434,417]	-2	hSpCas9	negative selection	9294491
239908602	239908625	1	-	27260156	TC71	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	0.04984616179189538	[720]	[751,696,860,894]	1	hSpCas9	negative selection	9294492
239907831	239907854	1	+	27260156	TC71	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.1100141633481172	[926]	[833,1099,1172,1191]	3	hSpCas9	negative selection	9358763
239907610	239907633	1	+	27260156	TC71	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.26424267374194454	[1046]	[1334,1596,1072,1398]	6	hSpCas9	negative selection	9358764
239908005	239908028	1	-	27260156	TC71	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.18422963098112	[1343]	[1302,1185,1148,1447]	-5	hSpCas9	negative selection	9358765
239909194	239909217	1	+	27260156	TC32	viability	TCACAAGCGCGCACCCGAGCAGG	CHRM3	ENSG00000133019	-0.23835633990461488	[477]	[360,206,700,355]	-4	hSpCas9	negative selection	9415741
239908229	239908252	1	+	27260156	TC32	viability	AAGCGTACCAAAGAGCTTGCTGG	CHRM3	ENSG00000133019	0.36161975035572097	[408]	[308,509,581,580]	6	hSpCas9	negative selection	9415742
239908602	239908625	1	-	27260156	TC32	viability	CACCTGCAGGTTGTCCGATGAGG	CHRM3	ENSG00000133019	-0.39863408557280366	[720]	[445,430,737,486]	-6	hSpCas9	negative selection	9415743
239907831	239907854	1	+	27260156	TC32	viability	CCTACATCATCATGAATCGATGG	CHRM3	ENSG00000133019	0.303507785939119	[926]	[1172,718,1289,1221]	5	hSpCas9	negative selection	9480014
239907610	239907633	1	+	27260156	TC32	viability	CGGTACCACCGATGACCCTCTGG	CHRM3	ENSG00000133019	0.2039930272006043	[1046]	[1058,918,1366,1256]	3	hSpCas9	negative selection	9480015
239908005	239908028	1	-	27260156	TC32	viability	AGCCAGACCGATCATCACACCGG	CHRM3	ENSG00000133019	-0.4164937241394582	[1343]	[859,615,1401,1075]	-7	hSpCas9	negative selection	9480016
239907778	239907801	1	-	27869803	HPAFII	viability after 27 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.1868921007188905	[173]	[69,88,NaN]	-1	hSpCas9	negative selection	9532895
239907877	239907900	1	-	27869803	HPAFII	viability after 27 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.004919078352335626	[415]	[279,168,NaN]	0	hSpCas9	negative selection	9532896
239908299	239908322	1	-	27869803	HPAFII	viability after 27 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.23933014524252516	[74]	[63,31,NaN]	2	hSpCas9	negative selection	9532897
239908492	239908515	1	+	27869803	HPAFII	viability after 27 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.10879546903724088	[287]	[219,115,NaN]	0	hSpCas9	negative selection	9532898
239908679	239908702	1	+	27869803	HPAFII	viability after 27 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-1.4080746236231712	[239]	[76,22,NaN]	-7	hSpCas9	negative selection	9532899
239907778	239907801	1	-	27869803	HPAFII	viability after 15 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.10242092632643285	[173]	[320,125,NaN]	1	hSpCas9	negative selection	9615344
239907877	239907900	1	-	27869803	HPAFII	viability after 15 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.025251517334122897	[415]	[582,349,NaN]	0	hSpCas9	negative selection	9615345
239908299	239908322	1	-	27869803	HPAFII	viability after 15 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.29833908070626647	[74]	[153,64,NaN]	3	hSpCas9	negative selection	9615346
239908492	239908515	1	+	27869803	HPAFII	viability after 15 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.4677820813552759	[287]	[744,230,NaN]	5	hSpCas9	negative selection	9615347
239908679	239908702	1	+	27869803	HPAFII	viability after 15 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.24393839908051435	[239]	[503,181,NaN]	3	hSpCas9	negative selection	9615348
239907778	239907801	1	-	27869803	ASPC1	viability after 36 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.6092862821762881	[347]	[252,130,178]	6	hSpCas9	negative selection	9697793
239907877	239907900	1	-	27869803	ASPC1	viability after 36 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.2505432718827084	[920]	[836,357,78]	2	hSpCas9	negative selection	9697794
239908299	239908322	1	-	27869803	ASPC1	viability after 36 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.018069777019769306	[187]	[34,166,7]	0	hSpCas9	negative selection	9697795
239908492	239908515	1	+	27869803	ASPC1	viability after 36 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.7641896859094018	[1012]	[724,495,589]	7	hSpCas9	negative selection	9697796
239908679	239908702	1	+	27869803	ASPC1	viability after 36 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	0.22564192168804095	[714]	[276,281,306]	2	hSpCas9	negative selection	9697797
239907778	239907801	1	-	27869803	PATU8988S	viability after 35 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.41827494637335894	[274]	[150,144,NaN]	5	hSpCas9	negative selection	9780242
239907877	239907900	1	-	27869803	PATU8988S	viability after 35 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.01093302338023383	[800]	[349,299,NaN]	0	hSpCas9	negative selection	9780243
239908299	239908322	1	-	27869803	PATU8988S	viability after 35 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-1.1522258223188626	[195]	[42,27,NaN]	-8	hSpCas9	negative selection	9780244
239908492	239908515	1	+	27869803	PATU8988S	viability after 35 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	-0.4679599644417124	[983]	[296,275,NaN]	-5	hSpCas9	negative selection	9780245
239908679	239908702	1	+	27869803	PATU8988S	viability after 35 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.5899547809240906	[729]	[338,50,NaN]	-5	hSpCas9	negative selection	9780246
239907778	239907801	1	-	27869803	PATU8988S	viability after 31 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.41698687918647026	[274]	[163,123,NaN]	5	hSpCas9	negative selection	9862691
239907877	239907900	1	-	27869803	PATU8988S	viability after 31 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	-0.06320458720895344	[800]	[222,410,NaN]	0	hSpCas9	negative selection	9862692
239908299	239908322	1	-	27869803	PATU8988S	viability after 31 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.8237640455089965	[195]	[15,79,NaN]	-7	hSpCas9	negative selection	9862693
239908492	239908515	1	+	27869803	PATU8988S	viability after 31 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	-0.2349507570609134	[983]	[317,352,NaN]	-3	hSpCas9	negative selection	9862694
239908679	239908702	1	+	27869803	PATU8988S	viability after 31 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-0.49618285380776816	[729]	[263,132,NaN]	-5	hSpCas9	negative selection	9862695
239907778	239907801	1	-	27869803	HPAFII	viability after 35 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	-0.38958337792059994	[173]	[78,53,NaN]	-2	hSpCas9	negative selection	9945140
239907877	239907900	1	-	27869803	HPAFII	viability after 35 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.3116507250754428	[415]	[314,200,NaN]	2	hSpCas9	negative selection	9945141
239908299	239908322	1	-	27869803	HPAFII	viability after 35 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-1.4516465826581577	[74]	[11,15,NaN]	-7	hSpCas9	negative selection	9945142
239908492	239908515	1	+	27869803	HPAFII	viability after 35 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.531721471480997	[287]	[230,187,NaN]	3	hSpCas9	negative selection	9945143
239908679	239908702	1	+	27869803	HPAFII	viability after 35 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-1.2126760976309312	[239]	[74,26,NaN]	-6	hSpCas9	negative selection	9945144
239907778	239907801	1	-	27869803	HPAFII	viability after 31 days	TAATCAGATCGGCACAGGCCAGG	CHRM3	ENSG00000133019	0.1421630256815033	[173]	[135,76,NaN]	1	hSpCas9	negative selection	10027589
239907877	239907900	1	-	27869803	HPAFII	viability after 31 days	CGTAGTCAATGGCAAGCCAGAGG	CHRM3	ENSG00000133019	0.2765697914562022	[415]	[389,165,NaN]	2	hSpCas9	negative selection	10027590
239908299	239908322	1	-	27869803	HPAFII	viability after 31 days	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.40175081620080966	[74]	[57,52,NaN]	3	hSpCas9	negative selection	10027591
239908492	239908515	1	+	27869803	HPAFII	viability after 31 days	GAACTCCGCCTCCTCCGACGAGG	CHRM3	ENSG00000133019	0.6797769568013682	[287]	[256,260,NaN]	5	hSpCas9	negative selection	10027592
239908679	239908702	1	+	27869803	HPAFII	viability after 31 days	GCCCAGAAGAGCGTGGACGATGG	CHRM3	ENSG00000133019	-2.181475380253855	[239]	[33,24,NaN]	-8	hSpCas9	negative selection	10027593
239907477	239907500	1	-	28162770	P31FUJ	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.3023567403861636	[166]	[241]	3	hSpCas9	negative selection	10133119
239908389	239908412	1	+	28162770	P31FUJ	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.6927478464257403	[337]	[641]	7	hSpCas9	negative selection	10133120
239907504	239907527	1	-	28162770	P31FUJ	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.34645898620994586	[65]	[60]	-3	hSpCas9	negative selection	10133121
239907520	239907543	1	-	28162770	P31FUJ	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.4827897389592605	[203]	[334]	5	hSpCas9	negative selection	10133122
239907540	239907563	1	-	28162770	P31FUJ	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.13492958008610856	[340]	[439]	1	hSpCas9	negative selection	10133123
239907626	239907649	1	-	28162770	P31FUJ	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.20590812384883272	[407]	[552]	2	hSpCas9	negative selection	10133124
239907912	239907935	1	-	28162770	P31FUJ	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-0.021072766140804167	[290]	[336]	0	hSpCas9	negative selection	10133125
239908100	239908123	1	-	28162770	P31FUJ	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.5015557161256727	[442]	[736]	5	hSpCas9	negative selection	10133126
239908137	239908160	1	-	28162770	P31FUJ	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.4123954034401476	[515]	[806]	4	hSpCas9	negative selection	10133127
239908299	239908322	1	-	28162770	P31FUJ	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.42082884143496013	[252]	[397]	5	hSpCas9	negative selection	10133128
239907477	239907500	1	-	28162770	TF1	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10302485
239908389	239908412	1	+	28162770	TF1	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10302486
239907504	239907527	1	-	28162770	TF1	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10302487
239907520	239907543	1	-	28162770	TF1	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10302488
239907540	239907563	1	-	28162770	TF1	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10302489
239907626	239907649	1	-	28162770	TF1	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10302490
239907912	239907935	1	-	28162770	TF1	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10302491
239908100	239908123	1	-	28162770	TF1	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10302492
239908137	239908160	1	-	28162770	TF1	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10302493
239908299	239908322	1	-	28162770	TF1	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10302494
239907477	239907500	1	-	28162770	SKM1	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.20714464763751106	[48]	[99]	2	hSpCas9	negative selection	10471851
239908389	239908412	1	+	28162770	SKM1	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.2594070103293039	[64]	[95]	-2	hSpCas9	negative selection	10471852
239907504	239907527	1	-	28162770	SKM1	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.6520766965796931	[15]	[17]	-5	hSpCas9	negative selection	10471853
239907520	239907543	1	-	28162770	SKM1	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.4035580023931252	[64]	[151]	4	hSpCas9	negative selection	10471854
239907540	239907563	1	-	28162770	SKM1	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	-0.7502110149539952	[97]	[102]	-5	hSpCas9	negative selection	10471855
239907626	239907649	1	-	28162770	SKM1	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	-0.3949915570770857	[89]	[120]	-3	hSpCas9	negative selection	10471856
239907912	239907935	1	-	28162770	SKM1	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.8280558309210354	[64]	[203]	7	hSpCas9	negative selection	10471857
239908100	239908123	1	-	28162770	SKM1	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	-0.4280874903089158	[85]	[112]	-4	hSpCas9	negative selection	10471858
239908137	239908160	1	-	28162770	SKM1	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.532226888768667	[105]	[270]	5	hSpCas9	negative selection	10471859
239908299	239908322	1	-	28162770	SKM1	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.16992500144231237	[48]	[76]	-1	hSpCas9	negative selection	10471860
239907477	239907500	1	-	28162770	SKM1	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.20714464763751106	[48]	[99]	2	hSpCas9	negative selection	10641217
239908389	239908412	1	+	28162770	SKM1	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.2594070103293039	[64]	[95]	-2	hSpCas9	negative selection	10641218
239907504	239907527	1	-	28162770	SKM1	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.6520766965796931	[15]	[17]	-5	hSpCas9	negative selection	10641219
239907520	239907543	1	-	28162770	SKM1	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.4035580023931252	[64]	[151]	4	hSpCas9	negative selection	10641220
239907540	239907563	1	-	28162770	SKM1	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	-0.7502110149539952	[97]	[102]	-5	hSpCas9	negative selection	10641221
239907626	239907649	1	-	28162770	SKM1	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	-0.3949915570770857	[89]	[120]	-3	hSpCas9	negative selection	10641222
239907912	239907935	1	-	28162770	SKM1	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.8280558309210354	[64]	[203]	7	hSpCas9	negative selection	10641223
239908100	239908123	1	-	28162770	SKM1	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	-0.4280874903089158	[85]	[112]	-4	hSpCas9	negative selection	10641224
239908137	239908160	1	-	28162770	SKM1	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.532226888768667	[105]	[270]	5	hSpCas9	negative selection	10641225
239908299	239908322	1	-	28162770	SKM1	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.16992500144231237	[48]	[76]	-1	hSpCas9	negative selection	10641226
239907477	239907500	1	-	28162770	PL21	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	-0.37650761801983235	[172]	[57]	-3	hSpCas9	negative selection	10810583
239908389	239908412	1	+	28162770	PL21	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.4697117838183492	[209]	[65]	-3	hSpCas9	negative selection	10810584
239907504	239907527	1	-	28162770	PL21	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.0343256391477027	[79]	[33]	0	hSpCas9	negative selection	10810585
239907520	239907543	1	-	28162770	PL21	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	-0.022252806847127875	[195]	[83]	0	hSpCas9	negative selection	10810586
239907540	239907563	1	-	28162770	PL21	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	-0.07320829995298062	[364]	[150]	0	hSpCas9	negative selection	10810587
239907626	239907649	1	-	28162770	PL21	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.2399406225472951	[285]	[146]	2	hSpCas9	negative selection	10810588
239907912	239907935	1	-	28162770	PL21	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-1.1921778082894403	[209]	[39]	-7	hSpCas9	negative selection	10810589
239908100	239908123	1	-	28162770	PL21	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.8294522076821021	[330]	[255]	7	hSpCas9	negative selection	10810590
239908137	239908160	1	-	28162770	PL21	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	1.1235980596163269	[328]	[311]	8	hSpCas9	negative selection	10810591
239908299	239908322	1	-	28162770	PL21	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.16911271886869575	[187]	[91]	1	hSpCas9	negative selection	10810592
239907477	239907500	1	-	28162770	P31FUJ	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.3023567403861636	[166]	[241]	3	hSpCas9	negative selection	10979949
239908389	239908412	1	+	28162770	P31FUJ	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.6927478464257403	[337]	[641]	7	hSpCas9	negative selection	10979950
239907504	239907527	1	-	28162770	P31FUJ	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.34645898620994586	[65]	[60]	-3	hSpCas9	negative selection	10979951
239907520	239907543	1	-	28162770	P31FUJ	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.4827897389592605	[203]	[334]	5	hSpCas9	negative selection	10979952
239907540	239907563	1	-	28162770	P31FUJ	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.13492958008610856	[340]	[439]	1	hSpCas9	negative selection	10979953
239907626	239907649	1	-	28162770	P31FUJ	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.20590812384883272	[407]	[552]	2	hSpCas9	negative selection	10979954
239907912	239907935	1	-	28162770	P31FUJ	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-0.021072766140804167	[290]	[336]	0	hSpCas9	negative selection	10979955
239908100	239908123	1	-	28162770	P31FUJ	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.5015557161256727	[442]	[736]	5	hSpCas9	negative selection	10979956
239908137	239908160	1	-	28162770	P31FUJ	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.4123954034401476	[515]	[806]	4	hSpCas9	negative selection	10979957
239908299	239908322	1	-	28162770	P31FUJ	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.42082884143496013	[252]	[397]	5	hSpCas9	negative selection	10979958
239907477	239907500	1	-	28162770	OCIAML5	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	-0.07762627127912769	[75]	[129]	0	hSpCas9	negative selection	11149315
239908389	239908412	1	+	28162770	OCIAML5	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	1.0473010660295121	[140]	[525]	8	hSpCas9	negative selection	11149316
239907504	239907527	1	-	28162770	OCIAML5	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.13837075602063797	[49]	[81]	-1	hSpCas9	negative selection	11149317
239907520	239907543	1	-	28162770	OCIAML5	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.5974593048001373	[92]	[253]	5	hSpCas9	negative selection	11149318
239907540	239907563	1	-	28162770	OCIAML5	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	-2.5289515610261923	[242]	[75]	-8	hSpCas9	negative selection	11149319
239907626	239907649	1	-	28162770	OCIAML5	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	-0.2918507324785264	[195]	[288]	-2	hSpCas9	negative selection	11149320
239907912	239907935	1	-	28162770	OCIAML5	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	1.0604705878856635	[135]	[511]	8	hSpCas9	negative selection	11149321
239908100	239908123	1	-	28162770	OCIAML5	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.35087348780627836	[191]	[441]	3	hSpCas9	negative selection	11149322
239908137	239908160	1	-	28162770	OCIAML5	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.6676499052417209	[195]	[561]	6	hSpCas9	negative selection	11149323
239908299	239908322	1	-	28162770	OCIAML5	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.714458681600483	[104]	[310]	6	hSpCas9	negative selection	11149324
239907477	239907500	1	-	28162770	EOL1	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.30822109994004315	[278]	[181]	3	hSpCas9	negative selection	11318681
239908389	239908412	1	+	28162770	EOL1	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.35019337041535925	[270]	[181]	3	hSpCas9	negative selection	11318682
239907504	239907527	1	-	28162770	EOL1	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.11049917552866617	[124]	[60]	-1	hSpCas9	negative selection	11318683
239907520	239907543	1	-	28162770	EOL1	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.7640830993772885	[398]	[356]	6	hSpCas9	negative selection	11318684
239907540	239907563	1	-	28162770	EOL1	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.24833620848342464	[619]	[387]	2	hSpCas9	negative selection	11318685
239907626	239907649	1	-	28162770	EOL1	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.26660582549227274	[668]	[423]	2	hSpCas9	negative selection	11318686
239907912	239907935	1	-	28162770	EOL1	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.8135164591817907	[323]	[299]	7	hSpCas9	negative selection	11318687
239908100	239908123	1	-	28162770	EOL1	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.45902882305432213	[474]	[343]	4	hSpCas9	negative selection	11318688
239908137	239908160	1	-	28162770	EOL1	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	-0.21356849164110187	[470]	[213]	-2	hSpCas9	negative selection	11318689
239908299	239908322	1	-	28162770	EOL1	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-1.2480026992786009	[274]	[60]	-7	hSpCas9	negative selection	11318690
239907477	239907500	1	-	28162770	MOLM13	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.26735639417187007	[261]	[227]	2	hSpCas9	negative selection	11488047
239908389	239908412	1	+	28162770	MOLM13	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.42575863728308744	[365]	[196]	-3	hSpCas9	negative selection	11488048
239907504	239907527	1	-	28162770	MOLM13	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	0.5655001781710012	[99]	[106]	4	hSpCas9	negative selection	11488049
239907520	239907543	1	-	28162770	MOLM13	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	-1.411429136032958	[297]	[80]	-6	hSpCas9	negative selection	11488050
239907540	239907563	1	-	28162770	MOLM13	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.8406986454341251	[467]	[605]	6	hSpCas9	negative selection	11488051
239907626	239907649	1	-	28162770	MOLM13	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	-0.013062234465605838	[514]	[368]	0	hSpCas9	negative selection	11488052
239907912	239907935	1	-	28162770	MOLM13	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-0.22370084774275303	[385]	[238]	-1	hSpCas9	negative selection	11488053
239908100	239908123	1	-	28162770	MOLM13	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.6328627403293592	[453]	[508]	5	hSpCas9	negative selection	11488054
239908137	239908160	1	-	28162770	MOLM13	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.878891367588266	[536]	[713]	6	hSpCas9	negative selection	11488055
239908299	239908322	1	-	28162770	MOLM13	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.26593055246255315	[221]	[192]	2	hSpCas9	negative selection	11488056
239907477	239907500	1	-	28162770	HEL	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.8962324706245446	[176]	[210]	7	hSpCas9	negative selection	11657413
239908389	239908412	1	+	28162770	HEL	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.6427388320003571	[317]	[317]	5	hSpCas9	negative selection	11657414
239907504	239907527	1	-	28162770	HEL	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-1.3180905707189652	[108]	[27]	-6	hSpCas9	negative selection	11657415
239907520	239907543	1	-	28162770	HEL	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.3797044261665631	[341]	[284]	3	hSpCas9	negative selection	11657416
239907540	239907563	1	-	28162770	HEL	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.7954420929140825	[411]	[457]	7	hSpCas9	negative selection	11657417
239907626	239907649	1	-	28162770	HEL	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	1.0756982392764631	[439]	[593]	8	hSpCas9	negative selection	11657418
239907912	239907935	1	-	28162770	HEL	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.7240389341022051	[275]	[291]	6	hSpCas9	negative selection	11657419
239908100	239908123	1	-	28162770	HEL	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.4844767480836246	[384]	[344]	4	hSpCas9	negative selection	11657420
239908137	239908160	1	-	28162770	HEL	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	1.0065510079240276	[386]	[497]	8	hSpCas9	negative selection	11657421
239908299	239908322	1	-	28162770	HEL	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.7162678674223223	[152]	[160]	6	hSpCas9	negative selection	11657422
239907477	239907500	1	-	28162770	MV411	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	-0.27812066274078523	[225]	[156]	-2	hSpCas9	negative selection	11826779
239908389	239908412	1	+	28162770	MV411	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	-0.019449180546624978	[224]	[186]	0	hSpCas9	negative selection	11826780
239907504	239907527	1	-	28162770	MV411	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-1.378747612664894	[70]	[22]	-7	hSpCas9	negative selection	11826781
239907520	239907543	1	-	28162770	MV411	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	-0.10117258675709254	[190]	[149]	-1	hSpCas9	negative selection	11826782
239907540	239907563	1	-	28162770	MV411	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.09167988126705695	[341]	[306]	0	hSpCas9	negative selection	11826783
239907626	239907649	1	-	28162770	MV411	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.9160579805508412	[267]	[425]	8	hSpCas9	negative selection	11826784
239907912	239907935	1	-	28162770	MV411	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.6766423819882132	[227]	[306]	6	hSpCas9	negative selection	11826785
239908100	239908123	1	-	28162770	MV411	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.5492912055070972	[274]	[338]	5	hSpCas9	negative selection	11826786
239908137	239908160	1	-	28162770	MV411	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.22748294440713046	[363]	[358]	2	hSpCas9	negative selection	11826787
239908299	239908322	1	-	28162770	MV411	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.0655992277969622	[151]	[133]	0	hSpCas9	negative selection	11826788
239907477	239907500	1	-	28162770	MONOMAC1	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.5569447241222538	[117]	[198]	5	hSpCas9	negative selection	11996145
239908389	239908412	1	+	28162770	MONOMAC1	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.1855791745269126	[134]	[175]	2	hSpCas9	negative selection	11996146
239907504	239907527	1	-	28162770	MONOMAC1	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-0.510194732319184	[40]	[32]	-4	hSpCas9	negative selection	11996147
239907520	239907543	1	-	28162770	MONOMAC1	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	-0.08600553467080965	[149]	[161]	0	hSpCas9	negative selection	11996148
239907540	239907563	1	-	28162770	MONOMAC1	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	-0.2531799250970874	[261]	[251]	-2	hSpCas9	negative selection	11996149
239907626	239907649	1	-	28162770	MONOMAC1	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	0.43136491492649964	[228]	[353]	4	hSpCas9	negative selection	11996150
239907912	239907935	1	-	28162770	MONOMAC1	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-0.27846444640339985	[163]	[154]	-2	hSpCas9	negative selection	11996151
239908100	239908123	1	-	28162770	MONOMAC1	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	0.3135783122015212	[218]	[311]	3	hSpCas9	negative selection	11996152
239908137	239908160	1	-	28162770	MONOMAC1	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.45309070032805876	[201]	[316]	4	hSpCas9	negative selection	11996153
239908299	239908322	1	-	28162770	MONOMAC1	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	0.5425734683622162	[108]	[181]	5	hSpCas9	negative selection	11996154
239907477	239907500	1	-	28162770	OCIAML2	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	-0.0011445419409410462	[25]	[143]	0	hSpCas9	negative selection	12165511
239908389	239908412	1	+	28162770	OCIAML2	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.3873511698854109	[27]	[202]	4	hSpCas9	negative selection	12165512
239907504	239907527	1	-	28162770	OCIAML2	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	-1.6863585162975983	[17]	[30]	-7	hSpCas9	negative selection	12165513
239907520	239907543	1	-	28162770	OCIAML2	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	0.08945800683996563	[38]	[229]	0	hSpCas9	negative selection	12165514
239907540	239907563	1	-	28162770	OCIAML2	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	-0.45940256981890715	[63]	[257]	-4	hSpCas9	negative selection	12165515
239907626	239907649	1	-	28162770	OCIAML2	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	-0.511271809739507	[71]	[279]	-4	hSpCas9	negative selection	12165516
239907912	239907935	1	-	28162770	OCIAML2	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	-0.9082098931720933	[42]	[126]	-6	hSpCas9	negative selection	12165517
239908100	239908123	1	-	28162770	OCIAML2	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	-0.8174958218794257	[61]	[194]	-5	hSpCas9	negative selection	12165518
239908137	239908160	1	-	28162770	OCIAML2	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	0.1253878639879905	[64]	[392]	1	hSpCas9	negative selection	12165519
239908299	239908322	1	-	28162770	OCIAML2	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.2517952233189026	[28]	[134]	-2	hSpCas9	negative selection	12165520
239907477	239907500	1	-	28162770	OCIAML3	viability	GATGTTTGGAAACAAAGGCGAGG	CHRM3	ENSG00000133019	0.24505614146077917	[44]	[160]	2	hSpCas9	negative selection	12334877
239908389	239908412	1	+	28162770	OCIAML3	viability	TCTGGTTCACAACCAAGAGCTGG	CHRM3	ENSG00000133019	0.36376412428653937	[51]	[201]	3	hSpCas9	negative selection	12334878
239907504	239907527	1	-	28162770	OCIAML3	viability	GGAGGGGCTGTGTATCCAGGAGG	CHRM3	ENSG00000133019	0.8585045643733437	[18]	[103]	7	hSpCas9	negative selection	12334879
239907520	239907543	1	-	28162770	OCIAML3	viability	GGGGCAGCCCTGCATCGGAGGGG	CHRM3	ENSG00000133019	-1.0559117446409811	[72]	[105]	-6	hSpCas9	negative selection	12334880
239907540	239907563	1	-	28162770	OCIAML3	viability	GAAATGAGTGACGGTTCCCGGGG	CHRM3	ENSG00000133019	0.24349689241314443	[114]	[410]	2	hSpCas9	negative selection	12334881
239907626	239907649	1	-	28162770	OCIAML3	viability	CAGACGGTATGACCTCCCAGAGG	CHRM3	ENSG00000133019	-0.3299001998251433	[111]	[268]	-3	hSpCas9	negative selection	12334882
239907912	239907935	1	-	28162770	OCIAML3	viability	GACCAGAAGATTCATAACAGAGG	CHRM3	ENSG00000133019	0.2072727673237565	[67]	[236]	2	hSpCas9	negative selection	12334883
239908100	239908123	1	-	28162770	OCIAML3	viability	TGAATGAAGCACTCTCCCGGAGG	CHRM3	ENSG00000133019	-0.15106414447543481	[95]	[260]	-1	hSpCas9	negative selection	12334884
239908137	239908160	1	-	28162770	OCIAML3	viability	GGCTGTGCCAAAAGTAATGGTGG	CHRM3	ENSG00000133019	-0.23645563570607941	[95]	[245]	-2	hSpCas9	negative selection	12334885
239908299	239908322	1	-	28162770	OCIAML3	viability	GCAGCTTCGAGAACTGCCCGTGG	CHRM3	ENSG00000133019	-0.5338866478865922	[46]	[97]	-4	hSpCas9	negative selection	12334886