Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1132
• Symbol:CHRM4
• Description:cholinergic receptor muscarinic 4

DataSource: http://genomecrispr.dkfz.de/#!/results/CHRM4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
46386183	46386206	11	+	26472758	Jiyoye	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.7778187614262637	[98]	[127]	5	hSpCas9	negative selection	31652
46385831	46385854	11	-	26472758	Jiyoye	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.6748711647095301	[102]	[123]	5	hSpCas9	negative selection	31653
46385868	46385891	11	-	26472758	Jiyoye	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.29643161571390175	[170]	[104]	-2	hSpCas9	negative selection	31654
46385751	46385774	11	+	26472758	Jiyoye	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	-0.5439150180131802	[173]	[89]	-4	hSpCas9	negative selection	31655
46385384	46385407	11	-	26472758	Jiyoye	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.5226525989258093	[23]	[25]	4	hSpCas9	negative selection	31656
46385253	46385276	11	-	26472758	Jiyoye	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	0.6659096499060417	[55]	[66]	5	hSpCas9	negative selection	31657
46386149	46386172	11	+	26472758	Jiyoye	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.16073748620277453	[120]	[101]	1	hSpCas9	negative selection	31658
46386057	46386080	11	+	26472758	Jiyoye	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.9979202348210359	[82]	[124]	6	hSpCas9	negative selection	31659
46385987	46386010	11	+	26472758	Jiyoye	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-1.0283262203326862	[283]	[104]	-6	hSpCas9	negative selection	31660
46385937	46385960	11	+	26472758	Jiyoye	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-1.8782268373563753	[38]	[7]	-8	hSpCas9	negative selection	31661
46386183	46386206	11	+	26472758	KBM7	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.4245136030380206	[442,321]	[94,165]	-4	hSpCas9	negative selection	222770
46385831	46385854	11	-	26472758	KBM7	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	-0.23276865920566392	[538,539]	[151,274]	-2	hSpCas9	negative selection	222771
46385868	46385891	11	-	26472758	KBM7	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.9133121629921843	[655,673]	[165,167]	-6	hSpCas9	negative selection	222772
46385751	46385774	11	+	26472758	KBM7	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	-0.014518258141455076	[499,276]	[196,157]	0	hSpCas9	negative selection	222773
46385384	46385407	11	-	26472758	KBM7	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	-0.1949103412803046	[286,239]	[111,103]	-2	hSpCas9	negative selection	222774
46385253	46385276	11	-	26472758	KBM7	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-0.2087148253017016	[356,311]	[176,98]	-2	hSpCas9	negative selection	222775
46386149	46386172	11	+	26472758	KBM7	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.1039180687925998	[985,933]	[422,418]	-1	hSpCas9	negative selection	222776
46386057	46386080	11	+	26472758	KBM7	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-0.09561285173521994	[339,285]	[161,114]	-1	hSpCas9	negative selection	222777
46385987	46386010	11	+	26472758	KBM7	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.3062250150947182	[732,689]	[444,386]	3	hSpCas9	negative selection	222778
46385937	46385960	11	+	26472758	KBM7	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-1.8509671958776495	[139,134]	[8,25]	-8	hSpCas9	negative selection	222779
46386183	46386206	11	+	26472758	Raji	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.030119988376335394	[175]	[39]	0	hSpCas9	negative selection	413888
46385831	46385854	11	-	26472758	Raji	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	-1.4286693648666102	[463]	[39]	-7	hSpCas9	negative selection	413889
46385868	46385891	11	-	26472758	Raji	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	0.5166386820584372	[249]	[82]	5	hSpCas9	negative selection	413890
46385751	46385774	11	+	26472758	Raji	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	-1.0045093446972977	[267]	[30]	-6	hSpCas9	negative selection	413891
46385384	46385407	11	-	26472758	Raji	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	-1.170601211926166	[96]	[9]	-7	hSpCas9	negative selection	413892
46385253	46385276	11	-	26472758	Raji	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	0.13775718441711837	[93]	[23]	1	hSpCas9	negative selection	413893
46386149	46386172	11	+	26472758	Raji	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.3249685492074136	[474]	[87]	-3	hSpCas9	negative selection	413894
46386057	46386080	11	+	26472758	Raji	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-1.0423635841310825	[141]	[15]	-6	hSpCas9	negative selection	413895
46385987	46386010	11	+	26472758	Raji	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.20584617425928786	[268]	[71]	2	hSpCas9	negative selection	413896
46385937	46385960	11	+	26472758	Raji	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-2.477578965347557	[95]	[3]	-9	hSpCas9	negative selection	413897
46386183	46386206	11	+	26472758	K562	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.5314865557661047	[362]	[211]	-3	hSpCas9	negative selection	605006
46385831	46385854	11	-	26472758	K562	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	-0.8921543252089974	[619]	[281]	-5	hSpCas9	negative selection	605007
46385868	46385891	11	-	26472758	K562	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.3573194858055359	[518]	[341]	-2	hSpCas9	negative selection	605008
46385751	46385774	11	+	26472758	K562	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.6229303509201768	[329]	[428]	5	hSpCas9	negative selection	605009
46385384	46385407	11	-	26472758	K562	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	1.7859886328742223	[89]	[261]	9	hSpCas9	negative selection	605010
46385253	46385276	11	-	26472758	K562	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-1.1286246829477697	[315]	[121]	-6	hSpCas9	negative selection	605011
46386149	46386172	11	+	26472758	K562	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.09140380887929633	[938]	[743]	0	hSpCas9	negative selection	605012
46386057	46386080	11	+	26472758	K562	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-0.10350457575385996	[237]	[186]	0	hSpCas9	negative selection	605013
46385987	46386010	11	+	26472758	K562	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.9830135654173116	[530]	[885]	8	hSpCas9	negative selection	605014
46385937	46385960	11	+	26472758	K562	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	0.26713880416653035	[62]	[63]	2	hSpCas9	negative selection	605015
46385138	46385161	11	+	26627737	DLD1	viability	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.11521895638423901	[596]	[193,304,123]	1	hSpCas9	negative selection	778616
46385387	46385410	11	+	26627737	DLD1	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.30927094905696256	[469]	[209,304,55]	3	hSpCas9	negative selection	778617
46385680	46385703	11	+	26627737	DLD1	viability	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	1.5512619101068867	[64]	[53,94,34]	9	hSpCas9	negative selection	778618
46385735	46385758	11	-	26627737	DLD1	viability	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	-0.5984722577263403	[807]	[204,186,116]	-5	hSpCas9	negative selection	778619
46385987	46386010	11	+	26627737	DLD1	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.8552136427968858	[286]	[89,282,124]	8	hSpCas9	negative selection	778620
46386467	46386490	11	-	26627737	DLD1	viability	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.1716697922660939	[1047]	[296,282,291]	-2	hSpCas9	negative selection	778621
46385138	46385161	11	+	26627737	GBM cells	viability after 5 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.1275382499336482	[296]	[174,172]	2	hSpCas9	negative selection	860931
46385387	46385410	11	+	26627737	GBM cells	viability after 5 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.18904194160175458	[210]	[129,127]	3	hSpCas9	negative selection	860932
46385680	46385703	11	+	26627737	GBM cells	viability after 5 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.37361197992540585	[121]	[44,55]	-5	hSpCas9	negative selection	860933
46385735	46385758	11	-	26627737	GBM cells	viability after 5 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.30878966904875044	[349]	[254,209]	5	hSpCas9	negative selection	860934
46385987	46386010	11	+	26627737	GBM cells	viability after 5 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.5262478416668657	[285]	[101,110]	-7	hSpCas9	negative selection	860935
46386467	46386490	11	-	26627737	GBM cells	viability after 5 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.49480490306968705	[514]	[227,163]	-7	hSpCas9	negative selection	860936
46385138	46385161	11	+	26627737	GBM cells	viability after 13 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.13718640829396517	[296]	[206,152]	1	hSpCas9	negative selection	943246
46385387	46385410	11	+	26627737	GBM cells	viability after 13 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.5253317432935338	[210]	[193,140]	6	hSpCas9	negative selection	943247
46385680	46385703	11	+	26627737	GBM cells	viability after 13 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-1.0236575484532258	[121]	[47,19]	-8	hSpCas9	negative selection	943248
46385735	46385758	11	-	26627737	GBM cells	viability after 13 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.10310933770674419	[349]	[214,194]	1	hSpCas9	negative selection	943249
46385987	46386010	11	+	26627737	GBM cells	viability after 13 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.950810072703864	[285]	[87,73]	-8	hSpCas9	negative selection	943250
46386467	46386490	11	-	26627737	GBM cells	viability after 13 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.7574981028873093	[514]	[188,145]	-7	hSpCas9	negative selection	943251
46385138	46385161	11	+	26627737	GBM cells	viability after 21 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.10489080278696267	[296]	[172,173]	1	hSpCas9	negative selection	1025561
46385387	46385410	11	+	26627737	GBM cells	viability after 21 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.8870545654716726	[210]	[211,211]	8	hSpCas9	negative selection	1025562
46385680	46385703	11	+	26627737	GBM cells	viability after 21 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-1.1629787672056404	[121]	[38,20]	-7	hSpCas9	negative selection	1025563
46385735	46385758	11	-	26627737	GBM cells	viability after 21 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.01973397895829959	[349]	[209,176]	0	hSpCas9	negative selection	1025564
46385987	46386010	11	+	26627737	GBM cells	viability after 21 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.9789041645444923	[285]	[70,85]	-7	hSpCas9	negative selection	1025565
46386467	46386490	11	-	26627737	GBM cells	viability after 21 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.6222514779441676	[514]	[198,165]	-5	hSpCas9	negative selection	1025566
46385138	46385161	11	+	26627737	RPE1	viability after 9 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.9024099551934817	[446]	[268,251]	6	hSpCas9	negative selection	1107876
46385387	46385410	11	+	26627737	RPE1	viability after 9 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.344053331816999	[545]	[374,509]	7	hSpCas9	negative selection	1107877
46385680	46385703	11	+	26627737	RPE1	viability after 9 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	5.162818246045764	[10]	[118,128]	9	hSpCas9	negative selection	1107878
46385735	46385758	11	-	26627737	RPE1	viability after 9 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	-0.0851507062644059	[1736]	[299,786]	0	hSpCas9	negative selection	1107879
46385987	46386010	11	+	26627737	RPE1	viability after 9 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	1.9973746252021816	[55]	[100,29]	8	hSpCas9	negative selection	1107880
46386467	46386490	11	-	26627737	RPE1	viability after 9 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-1.2302873290892502	[1553]	[264,132]	-7	hSpCas9	negative selection	1107881
46385138	46385161	11	+	26627737	RPE1	viability after 12 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	1.1724553301262466	[446]	[395,137]	7	hSpCas9	negative selection	1190191
46385387	46385410	11	+	26627737	RPE1	viability after 12 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.215893875232489	[545]	[297,385]	7	hSpCas9	negative selection	1190192
46385680	46385703	11	+	26627737	RPE1	viability after 12 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	5.757061314567066	[10]	[170,147]	9	hSpCas9	negative selection	1190193
46385735	46385758	11	-	26627737	RPE1	viability after 12 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.026207138394641172	[1736]	[380,574]	0	hSpCas9	negative selection	1190194
46385987	46386010	11	+	26627737	RPE1	viability after 12 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	3.0935788730723766	[55]	[227,22]	9	hSpCas9	negative selection	1190195
46386467	46386490	11	-	26627737	RPE1	viability after 12 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.6661136056181876	[1553]	[266,258]	-4	hSpCas9	negative selection	1190196
46385138	46385161	11	+	26627737	RPE1	viability after 15 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.601083569927227	[446]	[202,180]	4	hSpCas9	negative selection	1272506
46385387	46385410	11	+	26627737	RPE1	viability after 15 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.6658161750950558	[545]	[373,601]	8	hSpCas9	negative selection	1272507
46385680	46385703	11	+	26627737	RPE1	viability after 15 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	5.362393753579764	[10]	[211,46]	9	hSpCas9	negative selection	1272508
46385735	46385758	11	-	26627737	RPE1	viability after 15 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	-0.38932942825570593	[1736]	[366,382]	-2	hSpCas9	negative selection	1272509
46385987	46386010	11	+	26627737	RPE1	viability after 15 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	2.87897228541414	[55]	[170,63]	9	hSpCas9	negative selection	1272510
46386467	46386490	11	-	26627737	RPE1	viability after 15 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.6369792835202801	[1553]	[412,156]	-4	hSpCas9	negative selection	1272511
46385138	46385161	11	+	26627737	RPE1	viability after 18 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.7334900572116276	[446]	[187,213]	4	hSpCas9	negative selection	1354821
46385387	46385410	11	+	26627737	RPE1	viability after 18 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.8883402383806605	[545]	[559,529]	8	hSpCas9	negative selection	1354822
46385680	46385703	11	+	26627737	RPE1	viability after 18 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	5.441410892678494	[10]	[157,97]	9	hSpCas9	negative selection	1354823
46385735	46385758	11	-	26627737	RPE1	viability after 18 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.06391020641267198	[1736]	[416,567]	0	hSpCas9	negative selection	1354824
46385987	46386010	11	+	26627737	RPE1	viability after 18 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	1.4752817965012177	[55]	[27,56]	7	hSpCas9	negative selection	1354825
46386467	46386490	11	-	26627737	RPE1	viability after 18 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.27802772380757645	[1553]	[341,349]	-2	hSpCas9	negative selection	1354826
46385138	46385161	11	+	26627737	HeLa	viability after 8 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.1937823211019878	[680]	[254,271,249]	-2	hSpCas9	negative selection	1437136
46385387	46385410	11	+	26627737	HeLa	viability after 8 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.329900533256706	[288]	[238,5,240]	3	hSpCas9	negative selection	1437137
46385680	46385703	11	+	26627737	HeLa	viability after 8 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.33184011573736416	[240]	[68,126,52]	-3	hSpCas9	negative selection	1437138
46385735	46385758	11	-	26627737	HeLa	viability after 8 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.7703989517125225	[622]	[532,410,458]	6	hSpCas9	negative selection	1437139
46385987	46386010	11	+	26627737	HeLa	viability after 8 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.6086570396471227	[431]	[221,37,130]	-6	hSpCas9	negative selection	1437140
46386467	46386490	11	-	26627737	HeLa	viability after 8 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-1.1618814993522657	[884]	[100,98,291]	-8	hSpCas9	negative selection	1437141
46385138	46385161	11	+	26627737	HeLa	viability after 12 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.022248153170327245	[680]	[268,202,366]	0	hSpCas9	negative selection	1519451
46385387	46385410	11	+	26627737	HeLa	viability after 12 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.7473051040762859	[288]	[387,76,154]	6	hSpCas9	negative selection	1519452
46385680	46385703	11	+	26627737	HeLa	viability after 12 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	0.6280420491889982	[240]	[290,94,85]	5	hSpCas9	negative selection	1519453
46385735	46385758	11	-	26627737	HeLa	viability after 12 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.8200140380340903	[622]	[499,349,525]	6	hSpCas9	negative selection	1519454
46385987	46386010	11	+	26627737	HeLa	viability after 12 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.6017566402327083	[431]	[191,42,127]	-5	hSpCas9	negative selection	1519455
46386467	46386490	11	-	26627737	HeLa	viability after 12 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.5631624737142508	[884]	[409,212,127]	-5	hSpCas9	negative selection	1519456
46385138	46385161	11	+	26627737	HeLa	viability after 15 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.32279489644208065	[680]	[157,186,328]	-3	hSpCas9	negative selection	1601766
46385387	46385410	11	+	26627737	HeLa	viability after 15 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.0764757236291271	[288]	[142,350,251]	7	hSpCas9	negative selection	1601767
46385680	46385703	11	+	26627737	HeLa	viability after 15 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-1.9651834812609632	[240]	[47,2,23]	-9	hSpCas9	negative selection	1601768
46385735	46385758	11	-	26627737	HeLa	viability after 15 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	1.0683500298726953	[622]	[658,498,427]	7	hSpCas9	negative selection	1601769
46385987	46386010	11	+	26627737	HeLa	viability after 15 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.9631107651149646	[431]	[72,117,78]	-7	hSpCas9	negative selection	1601770
46386467	46386490	11	-	26627737	HeLa	viability after 15 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-1.8686662102024547	[884]	[120,47,128]	-9	hSpCas9	negative selection	1601771
46385138	46385161	11	+	26627737	HeLa	viability after 18 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.3177361440183001	[680]	[104,157,328]	-3	hSpCas9	negative selection	1684081
46385387	46385410	11	+	26627737	HeLa	viability after 18 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.0739088133714807	[288]	[97,286,251]	7	hSpCas9	negative selection	1684082
46385680	46385703	11	+	26627737	HeLa	viability after 18 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-1.9532405029070121	[240]	[32,1,23]	-9	hSpCas9	negative selection	1684083
46385735	46385758	11	-	26627737	HeLa	viability after 18 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	1.0567070806610623	[622]	[441,402,427]	7	hSpCas9	negative selection	1684084
46385987	46386010	11	+	26627737	HeLa	viability after 18 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.9925653457019471	[431]	[45,96,78]	-7	hSpCas9	negative selection	1684085
46386467	46386490	11	-	26627737	HeLa	viability after 18 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-1.8775895125431714	[884]	[78,40,128]	-9	hSpCas9	negative selection	1684086
46385138	46385161	11	+	26627737	HCT116	viability after 6 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	1.1350635923942862	[500]	[424,33]	6	hSpCas9	negative selection	1766396
46385387	46385410	11	+	26627737	HCT116	viability after 6 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.1089884343942829	[748]	[534,98]	6	hSpCas9	negative selection	1766397
46385680	46385703	11	+	26627737	HCT116	viability after 6 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.8355934945183192	[251]	[27,18]	-5	hSpCas9	negative selection	1766398
46385735	46385758	11	-	26627737	HCT116	viability after 6 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.6260621899241738	[824]	[272,159]	3	hSpCas9	negative selection	1766399
46385987	46386010	11	+	26627737	HCT116	viability after 6 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.5398073245370764	[497]	[292,14]	3	hSpCas9	negative selection	1766400
46386467	46386490	11	-	26627737	HCT116	viability after 6 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	0.7867862784579663	[1197]	[273,352]	4	hSpCas9	negative selection	1766401
46385138	46385161	11	+	26627737	HCT116	viability after 8 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.30643144347057116	[431]	[166,215,193]	-4	hSpCas9	negative selection	1848711
46385387	46385410	11	+	26627737	HCT116	viability after 8 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.11792368741279491	[251]	[189,131,130]	1	hSpCas9	negative selection	1848712
46385680	46385703	11	+	26627737	HCT116	viability after 8 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.3139984442672119	[132]	[55,77,42]	-4	hSpCas9	negative selection	1848713
46385735	46385758	11	-	26627737	HCT116	viability after 8 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.3457173439114156	[407]	[268,236,349]	4	hSpCas9	negative selection	1848714
46385987	46386010	11	+	26627737	HCT116	viability after 8 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-1.035498035235625	[441]	[148,89,117]	-8	hSpCas9	negative selection	1848715
46386467	46386490	11	-	26627737	HCT116	viability after 8 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.403012530426906	[468]	[122,262,198]	-5	hSpCas9	negative selection	1848716
46385138	46385161	11	+	26627737	HCT116	viability after 9 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	1.5722616909704454	[500]	[370,418]	8	hSpCas9	negative selection	1931026
46385387	46385410	11	+	26627737	HCT116	viability after 9 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.2228063789024362	[748]	[448,62]	1	hSpCas9	negative selection	1931027
46385680	46385703	11	+	26627737	HCT116	viability after 9 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.08411721900158997	[251]	[15,100]	0	hSpCas9	negative selection	1931028
46385735	46385758	11	-	26627737	HCT116	viability after 9 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.8101390374487438	[824]	[545,259]	6	hSpCas9	negative selection	1931029
46385987	46386010	11	+	26627737	HCT116	viability after 9 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.9401565996277521	[497]	[124,357]	6	hSpCas9	negative selection	1931030
46386467	46386490	11	-	26627737	HCT116	viability after 9 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.210310214561355	[1197]	[266,283]	-1	hSpCas9	negative selection	1931031
46385138	46385161	11	+	26627737	HCT116	viability after 12 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.0373213590797985	[431]	[206,264,193]	0	hSpCas9	negative selection	2013341
46385387	46385410	11	+	26627737	HCT116	viability after 12 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.5015533278128557	[251]	[248,225,82]	5	hSpCas9	negative selection	2013342
46385680	46385703	11	+	26627737	HCT116	viability after 12 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.39747472329469224	[132]	[52,44,60]	-4	hSpCas9	negative selection	2013343
46385735	46385758	11	-	26627737	HCT116	viability after 12 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.13260434482905736	[407]	[215,323,168]	1	hSpCas9	negative selection	2013344
46385987	46386010	11	+	26627737	HCT116	viability after 12 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.018390070466913544	[441]	[280,120,296]	0	hSpCas9	negative selection	2013345
46386467	46386490	11	-	26627737	HCT116	viability after 12 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.07617316978438193	[468]	[332,205,152]	0	hSpCas9	negative selection	2013346
46385138	46385161	11	+	26627737	HCT116	viability after 15 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.2001636346398033	[431]	[231,299,118]	-2	hSpCas9	negative selection	2095656
46385387	46385410	11	+	26627737	HCT116	viability after 15 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.008934737678301	[251]	[267,236,364]	8	hSpCas9	negative selection	2095657
46385680	46385703	11	+	26627737	HCT116	viability after 15 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	0.1091943358995815	[132]	[65,82,95]	1	hSpCas9	negative selection	2095658
46385735	46385758	11	-	26627737	HCT116	viability after 15 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.2463894497781528	[407]	[229,318,278]	2	hSpCas9	negative selection	2095659
46385987	46386010	11	+	26627737	HCT116	viability after 15 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-1.011978240150699	[441]	[178,72,131]	-7	hSpCas9	negative selection	2095660
46386467	46386490	11	-	26627737	HCT116	viability after 15 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.28921623075750175	[468]	[352,154,169]	-3	hSpCas9	negative selection	2095661
46385138	46385161	11	+	26627737	HCT116	viability after 18 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.06019867381244948	[431]	[143,222,233]	0	hSpCas9	negative selection	2177971
46385387	46385410	11	+	26627737	HCT116	viability after 18 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.7977657190102955	[251]	[220,253,154]	6	hSpCas9	negative selection	2177972
46385680	46385703	11	+	26627737	HCT116	viability after 18 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.25389182875665073	[132]	[35,84,37]	-2	hSpCas9	negative selection	2177973
46385735	46385758	11	-	26627737	HCT116	viability after 18 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.7544664949432517	[407]	[260,552,161]	6	hSpCas9	negative selection	2177974
46385987	46386010	11	+	26627737	HCT116	viability after 18 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.6764603850038352	[441]	[79,130,192]	-6	hSpCas9	negative selection	2177975
46386467	46386490	11	-	26627737	HCT116	viability after 18 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.10128576961494651	[468]	[226,162,248]	-1	hSpCas9	negative selection	2177976
46385921	46385944	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGCCTGTGGTCATCATGACGG	CHRM4	ENSG00000180720	0.1262765137930804	[3,3]	[3,2]	2	hSpCas9	positive selection	2979190
46386150	46386173	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.0755256233528091	[3,3]	[3,2]	1	hSpCas9	positive selection	2979191
46386268	46386291	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGCCCTTGATGATGTACACGG	CHRM4	ENSG00000180720	0.06329699816730505	[3,4]	[3,3]	1	hSpCas9	positive selection	2979192
46386020	46386043	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTGTGGTGGGTAAGCGGACGG	CHRM4	ENSG00000180720	0.420519368047659	[3,3]	[4,3]	8	hSpCas9	positive selection	2979193
46385921	46385944	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGCCTGTGGTCATCATGACGG	CHRM4	ENSG00000180720	0.21652009184085946	[3,3]	[3,2]	4	hSpCas9	positive selection	3047048
46386150	46386173	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.2298022512917676	[3,3]	[3,0]	-3	hSpCas9	positive selection	3047049
46386268	46386291	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGCCCTTGATGATGTACACGG	CHRM4	ENSG00000180720	0.4896191511223222	[3,3]	[4,3]	8	hSpCas9	positive selection	3047050
46386020	46386043	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTGTGGTGGGTAAGCGGACGG	CHRM4	ENSG00000180720	0.8229110428388989	[3,3]	[3,4]	9	hSpCas9	positive selection	3047051
46385405	46385428		-	24336571	A375	resistance to PLX after 7 days	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	-0.14033352160985563	[17,16]	[15,15]	-4	hSpCas9	positive selection	3105544
46385874	46385897		+	24336571	A375	resistance to PLX after 7 days	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.011898085210295326	[14,12]	[15,11]	0	hSpCas9	positive selection	3105546
46385405	46385428		-	24336571	A375	resistance to PLX after 14 days	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	-0.14150826548687157	[14,18]	[5,7]	-1	hSpCas9	positive selection	3163337
46385874	46385897		+	24336571	A375	resistance to PLX after 14 days	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.27851441638679697	[17,12]	[6,8]	3	hSpCas9	positive selection	3163339
46385405	46385428		-	24336571	A375	viability after 7 days	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.24936171832585896	[14]	[17,16]	4	hSpCas9	negative selection	3221130
46385874	46385897		+	24336571	A375	viability after 7 days	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.005568857358083407	[14]	[14,12]	0	hSpCas9	negative selection	3221132
46385405	46385428		-	24336571	A375	viability after 14 days	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.22858480182826674	[14]	[14,18]	3	hSpCas9	negative selection	3278923
46385874	46385897		+	24336571	A375	viability after 14 days	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.12514133708812503	[14]	[17,12]	1	hSpCas9	negative selection	3278925
46385405	46385428	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	-0.9588965779571826	[280,313]	[0,0]	-6	hSpCas9	positive selection	3343108
46385126	46385149	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.22706890854592107	[189,167]	[0,0]	-1	hSpCas9	positive selection	3343109
46385357	46385380	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	-1.025686462391393	[308,313]	[0,0]	-7	hSpCas9	positive selection	3343110
46386467	46386490	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.2345268848838394	[179,179]	[0,0]	-1	hSpCas9	positive selection	3362333
46385874	46385897	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	1.0285075209499543	[74,74]	[0,0]	5	hSpCas9	positive selection	3362334
46385387	46385410	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-1.5403353144079248	[444,444]	[0,0]	-8	hSpCas9	positive selection	3362335
46385921	46385944	11	-	26780180	HT29	viability (Avana library 4 designs)	CCTGCCTGTGGTCATCATGACGG	CHRM4	ENSG00000180720	0.973265490618515	[]	[]	4	hSpCas9	negative selection	3415593
46386149	46386172	11	+	26780180	HT29	viability (Avana library 4 designs)	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.21555209167238	[]	[]	-3	hSpCas9	negative selection	3415594
46386267	46386290	11	+	26780180	HT29	viability (Avana library 4 designs)	GTAGCCCTTGATGATGTACACGG	CHRM4	ENSG00000180720	-0.8112911661869	[]	[]	-9	hSpCas9	negative selection	3415595
46386020	46386043	11	-	26780180	HT29	viability (Avana library 4 designs)	GTTTGTGGTGGGTAAGCGGACGG	CHRM4	ENSG00000180720	2.05367301644487	[]	[]	7	hSpCas9	negative selection	3415596
46386267	46386290	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGCCCTTGATGATGTACACGG	CHRM4	ENSG00000180720	3.4367273268664	[]	[]	5	hSpCas9	negative selection	3492696
46386020	46386043	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTGTGGTGGGTAAGCGGACGG	CHRM4	ENSG00000180720	2.22206262756467	[]	[]	3	hSpCas9	negative selection	3492697
46386149	46386172	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	3.47507558266241	[]	[]	5	hSpCas9	negative selection	3492698
46385921	46385944	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCCTGTGGTCATCATGACGG	CHRM4	ENSG00000180720	-0.777857987429533	[]	[]	-1	hSpCas9	negative selection	3492699
46385937	46385960	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-6.8742034682116	[]	[]	-6	hSpCas9	negative selection	3492700
46386532	46386555	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAACTTCACACCTGTCAATGG	CHRM4	ENSG00000180720	0.629178366004425	[]	[]	0	hSpCas9	negative selection	3492701
46386267	46386290	11	+	26780180	A375	viability (Avana lentiGuide)	GTAGCCCTTGATGATGTACACGG	CHRM4	ENSG00000180720	-0.851583011540067	[]	[]	-1	hSpCas9	negative selection	3601355
46386020	46386043	11	-	26780180	A375	viability (Avana lentiGuide)	GTTTGTGGTGGGTAAGCGGACGG	CHRM4	ENSG00000180720	1.80883283869183	[]	[]	2	hSpCas9	negative selection	3601356
46386149	46386172	11	+	26780180	A375	viability (Avana lentiGuide)	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	1.84964659098908	[]	[]	2	hSpCas9	negative selection	3601357
46385921	46385944	11	-	26780180	A375	viability (Avana lentiGuide)	CCTGCCTGTGGTCATCATGACGG	CHRM4	ENSG00000180720	-3.14354046376777	[]	[]	-5	hSpCas9	negative selection	3601358
46385937	46385960	11	+	26780180	A375	viability (Avana lentiGuide)	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	21.0276174446791	[]	[]	8	hSpCas9	negative selection	3601359
46386532	46386555	11	-	26780180	A375	viability (Avana lentiGuide)	GCCAACTTCACACCTGTCAATGG	CHRM4	ENSG00000180720	5.9049986682552	[]	[]	5	hSpCas9	negative selection	3601360
46386267	46386290	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGCCCTTGATGATGTACACGG	CHRM4	ENSG00000180720	0.31411139048472014	[5]	[6,7]	8	hSpCas9	positive selection	3710014
46386020	46386043	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTGTGGTGGGTAAGCGGACGG	CHRM4	ENSG00000180720	-0.002562255680038955	[4]	[5,3]	0	hSpCas9	positive selection	3710015
46386149	46386172	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.09489857757832476	[3]	[4,4]	2	hSpCas9	positive selection	3710016
46385921	46385944	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCCTGTGGTCATCATGACGG	CHRM4	ENSG00000180720	0.0720810840407726	[4]	[5,3]	1	hSpCas9	positive selection	3710017
46385937	46385960	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-0.7288093130982536	[4]	[3,0]	-8	hSpCas9	positive selection	3710018
46386532	46386555	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAACTTCACACCTGTCAATGG	CHRM4	ENSG00000180720	-0.2742725797661004	[4]	[4,2]	-4	hSpCas9	positive selection	3710019
46386267	46386290	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGCCCTTGATGATGTACACGG	CHRM4	ENSG00000180720	0.20079301228250795	[6]	[6,5]	5	hSpCas9	positive selection	3818621
46386020	46386043	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTGTGGTGGGTAAGCGGACGG	CHRM4	ENSG00000180720	-0.14568314478524705	[5]	[3,4]	-2	hSpCas9	positive selection	3818622
46386149	46386172	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.4129286429384663	[5]	[1,4]	-5	hSpCas9	positive selection	3818623
46385921	46385944	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCCTGTGGTCATCATGACGG	CHRM4	ENSG00000180720	0.33509357011588914	[4]	[5,5]	8	hSpCas9	positive selection	3818624
46385937	46385960	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-0.8490889916368983	[5]	[0,2]	-8	hSpCas9	positive selection	3818625
46386532	46386555	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAACTTCACACCTGTCAATGG	CHRM4	ENSG00000180720	0.09782902634362929	[4]	[3,4]	2	hSpCas9	positive selection	3818626
46385126	46385149	11	+	26780180	A375	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	1.21913382059123	[]	[]	6	hSpCas9	negative selection	3926684
46386467	46386490	11	+	26780180	A375	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	1.01912983857133	[]	[]	5	hSpCas9	negative selection	3926685
46385405	46385428	11	-	26780180	A375	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	1.13156751505458	[]	[]	6	hSpCas9	negative selection	3926686
46385874	46385897	11	+	26780180	A375	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	1.04241621712348	[]	[]	5	hSpCas9	negative selection	3926687
46385387	46385410	11	+	26780180	A375	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.872404576659881	[]	[]	3	hSpCas9	negative selection	3926688
46385357	46385380	11	+	26780180	A375	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.309274714768027	[]	[]	0	hSpCas9	negative selection	3926689
46385126	46385149	11	+	26780180	HT29	viability (GeCKOv2 library)	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	0.730845788482533	[]	[]	3	hSpCas9	negative selection	4034650
46386467	46386490	11	+	26780180	HT29	viability (GeCKOv2 library)	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.884133996867278	[]	[]	4	hSpCas9	negative selection	4034651
46385405	46385428	11	-	26780180	HT29	viability (GeCKOv2 library)	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	1.51844916762976	[]	[]	7	hSpCas9	negative selection	4034652
46385874	46385897	11	+	26780180	HT29	viability (GeCKOv2 library)	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	1.35714550436834	[]	[]	7	hSpCas9	negative selection	4034653
46385387	46385410	11	+	26780180	HT29	viability (GeCKOv2 library)	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	1.80826178799066	[]	[]	8	hSpCas9	negative selection	4034654
46385357	46385380	11	+	26780180	HT29	viability (GeCKOv2 library)	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.168701855588861	[]	[]	0	hSpCas9	negative selection	4034655
46385405	46385428	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.022319638884372592	[3]	[2,2]	0	hSpCas9	positive selection	4127650
46385874	46385897	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.1987235082304869	[3]	[2,2]	5	hSpCas9	positive selection	4127653
46385405	46385428	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	1.089650337156083	[3]	[4,2,3,3]	7	hSpCas9	positive selection	4191672
46385874	46385897	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.02701590181506515	[3]	[0,3,1,0]	0	hSpCas9	positive selection	4191675
46385405	46385428	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.08070629822032324	[3]	[3,2]	1	hSpCas9	positive selection	4263252
46385126	46385149	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	0.18923995793898807	[3]	[3,3]	4	hSpCas9	positive selection	4263253
46385357	46385380	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.29980168830584947	[4]	[4,3]	6	hSpCas9	positive selection	4263254
46386467	46386490	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.1564856291134401	[2]	[3,1]	3	hSpCas9	positive selection	4327525
46385874	46385897	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.31535594429492114	[2]	[1,0]	-6	hSpCas9	positive selection	4327526
46385387	46385410	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.2932965814842844	[4]	[3,4]	6	hSpCas9	positive selection	4327527
46385860	46385882	11	-	27760321	OCIAML3	viability	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	-0.08817523172537955	[939,772]	[568,702]	-1	hSpCas9	negative selection	4389287
46385875	46385897	11	+	27760321	OCIAML3	viability	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.29197334586498147	[441,465]	[407,474]	3	hSpCas9	negative selection	4389288
46385976	46385998	11	+	27760321	OCIAML3	viability	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.051459255802759354	[508,389]	[284,403]	0	hSpCas9	negative selection	4389289
46386242	46386264	11	+	27760321	OCIAML3	viability	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.3084766266886978	[750,618]	[596,742]	3	hSpCas9	negative selection	4389290
46386414	46386436	11	+	27760321	OCIAML3	viability	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.15456468920618827	[1012,855]	[731,912]	1	hSpCas9	negative selection	4389291
46385860	46385882	11	-	27760321	OCIAML2	viability	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	-0.2673756551779304	[939,772]	[559,589]	-3	hSpCas9	negative selection	4472750
46385875	46385897	11	+	27760321	OCIAML2	viability	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.5341046851222726	[441,465]	[491,590]	7	hSpCas9	negative selection	4472751
46385976	46385998	11	+	27760321	OCIAML2	viability	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.33093657079493743	[508,389]	[238,349]	-4	hSpCas9	negative selection	4472752
46386242	46386264	11	+	27760321	OCIAML2	viability	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	-0.23249350538949282	[750,618]	[336,643]	-3	hSpCas9	negative selection	4472753
46386414	46386436	11	+	27760321	OCIAML2	viability	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.4943170166413986	[1012,855]	[947,1209]	6	hSpCas9	negative selection	4472754
46385860	46385882	11	-	27760321	MV411	viability	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	-0.6483737823117219	[939,772]	[236,541]	-4	hSpCas9	negative selection	4556213
46385875	46385897	11	+	27760321	MV411	viability	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.6808903292470352	[441,465]	[372,647]	5	hSpCas9	negative selection	4556214
46385976	46385998	11	+	27760321	MV411	viability	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-1.6056815559407052	[508,389]	[7,229]	-8	hSpCas9	negative selection	4556215
46386242	46386264	11	+	27760321	MV411	viability	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	-0.007520900812986175	[750,618]	[208,805]	0	hSpCas9	negative selection	4556216
46386414	46386436	11	+	27760321	MV411	viability	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.7090437280743254	[1012,855]	[1310,543]	5	hSpCas9	negative selection	4556217
46385860	46385882	11	-	27760321	HL60	viability	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.04600264958171574	[939,772]	[682,756]	0	hSpCas9	negative selection	4639676
46385875	46385897	11	+	27760321	HL60	viability	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.33061280311590424	[441,465]	[399,541]	4	hSpCas9	negative selection	4639677
46385976	46385998	11	+	27760321	HL60	viability	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.3204536770260303	[508,389]	[318,262]	-4	hSpCas9	negative selection	4639678
46386242	46386264	11	+	27760321	HL60	viability	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.5937516213115273	[750,618]	[908,767]	7	hSpCas9	negative selection	4639679
46386414	46386436	11	+	27760321	HL60	viability	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	-0.23750248654229367	[1012,855]	[633,656]	-3	hSpCas9	negative selection	4639680
46385860	46385882	11	-	27760321	HT1080	viability	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	-0.5442960548706599	[772,602]	[154,223]	-2	hSpCas9	negative selection	4723139
46385875	46385897	11	+	27760321	HT1080	viability	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.8335557498465208	[465,363]	[444,129]	4	hSpCas9	negative selection	4723140
46385976	46385998	11	+	27760321	HT1080	viability	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-6.506651057400514	[389,304]	[1,0]	-9	hSpCas9	negative selection	4723141
46386242	46386264	11	+	27760321	HT1080	viability	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.6744458036416717	[618,482]	[219,492]	3	hSpCas9	negative selection	4723142
46386414	46386436	11	+	27760321	HT1080	viability	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.007109240928243388	[855,667]	[242,372]	0	hSpCas9	negative selection	4723143
46385860	46385882	11	-	27760321	HT29	viability after 7 days	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.3627973936480857	[772,602]	[1062,910,1416]	5	hSpCas9	negative selection	4806602
46385875	46385897	11	+	27760321	HT29	viability after 7 days	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.5753408834542306	[465,363]	[233,332,484]	-7	hSpCas9	negative selection	4806603
46385976	46385998	11	+	27760321	HT29	viability after 7 days	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.5036791472155694	[389,304]	[522,210,242]	-6	hSpCas9	negative selection	4806604
46386242	46386264	11	+	27760321	HT29	viability after 7 days	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.6910492970587186	[618,482]	[1000,1037,1362]	9	hSpCas9	negative selection	4806605
46386414	46386436	11	+	27760321	HT29	viability after 7 days	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.28055145833053974	[855,667]	[1334,1191,1065]	4	hSpCas9	negative selection	4806606
46385860	46385882	11	-	27760321	HT29	viability after 25 days	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.3142354246445951	[772,602]	[960,1133,820]	3	hSpCas9	negative selection	4890065
46385875	46385897	11	+	27760321	HT29	viability after 25 days	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.13112340607952985	[465,363]	[298,428,595]	-1	hSpCas9	negative selection	4890066
46385976	46385998	11	+	27760321	HT29	viability after 25 days	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	0.14929952570013552	[389,304]	[325,483,526]	1	hSpCas9	negative selection	4890067
46386242	46386264	11	+	27760321	HT29	viability after 25 days	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.8364334648652479	[618,482]	[1102,936,1356]	8	hSpCas9	negative selection	4890068
46386414	46386436	11	+	27760321	HT29	viability after 25 days	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.2700320120557316	[855,667]	[934,1005,1233]	3	hSpCas9	negative selection	4890069
46385860	46385882	11	-	27760321	HT29	viability after 22 days	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.12871384880473147	[772,602]	[1031,832,737]	1	hSpCas9	negative selection	4973528
46385875	46385897	11	+	27760321	HT29	viability after 22 days	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.3122734562918857	[465,363]	[345,353,460]	-3	hSpCas9	negative selection	4973529
46385976	46385998	11	+	27760321	HT29	viability after 22 days	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	0.11231739646517686	[389,304]	[555,268,474]	1	hSpCas9	negative selection	4973530
46386242	46386264	11	+	27760321	HT29	viability after 22 days	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.9202819828002234	[618,482]	[1131,1210,1275]	9	hSpCas9	negative selection	4973531
46386414	46386436	11	+	27760321	HT29	viability after 22 days	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.2751114965627539	[855,667]	[705,1079,1424]	3	hSpCas9	negative selection	4973532
46385860	46385882	11	-	27760321	HT29	viability after 19 days	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.11334752149194127	[772,602]	[1176,613,797]	1	hSpCas9	negative selection	5056991
46385875	46385897	11	+	27760321	HT29	viability after 19 days	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.4669582105861171	[465,363]	[430,233,372]	-4	hSpCas9	negative selection	5056992
46385976	46385998	11	+	27760321	HT29	viability after 19 days	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.11057333774351366	[389,304]	[510,342,268]	-1	hSpCas9	negative selection	5056993
46386242	46386264	11	+	27760321	HT29	viability after 19 days	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.9510089905580522	[618,482]	[1271,1396,998]	8	hSpCas9	negative selection	5056994
46386414	46386436	11	+	27760321	HT29	viability after 19 days	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.6123259527474205	[855,667]	[1198,1051,1715]	6	hSpCas9	negative selection	5056995
46385860	46385882	11	-	27760321	HT29	viability after 16 days	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.0920893539476908	[772,602]	[936,828,705]	1	hSpCas9	negative selection	5140454
46385875	46385897	11	+	27760321	HT29	viability after 16 days	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.49744476077292976	[465,363]	[463,230,306]	-5	hSpCas9	negative selection	5140455
46385976	46385998	11	+	27760321	HT29	viability after 16 days	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	0.32051962161814646	[389,304]	[426,603,416]	3	hSpCas9	negative selection	5140456
46386242	46386264	11	+	27760321	HT29	viability after 16 days	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.9066136107934387	[618,482]	[1003,1054,1395]	9	hSpCas9	negative selection	5140457
46386414	46386436	11	+	27760321	HT29	viability after 16 days	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.29480459701837036	[855,667]	[1264,890,1005]	3	hSpCas9	negative selection	5140458
46385860	46385882	11	-	27760321	HT29	viability after 13 days	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.5566860920632022	[772,602]	[1656,1157,732]	7	hSpCas9	negative selection	5223917
46385875	46385897	11	+	27760321	HT29	viability after 13 days	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.5150175843403947	[465,363]	[295,295,413]	-5	hSpCas9	negative selection	5223918
46385976	46385998	11	+	27760321	HT29	viability after 13 days	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.12773663518405426	[389,304]	[294,371,435]	-1	hSpCas9	negative selection	5223919
46386242	46386264	11	+	27760321	HT29	viability after 13 days	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.9368900655719966	[618,482]	[1384,1291,1006]	9	hSpCas9	negative selection	5223920
46386414	46386436	11	+	27760321	HT29	viability after 13 days	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.25917522685183747	[855,667]	[1211,897,1062]	3	hSpCas9	negative selection	5223921
46385860	46385882	11	-	27760321	HT29	viability after 10 days	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.2733881171392807	[772,602]	[1146,1000,966]	3	hSpCas9	negative selection	5307380
46385875	46385897	11	+	27760321	HT29	viability after 10 days	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.4644460976277328	[465,363]	[337,540,254]	-5	hSpCas9	negative selection	5307381
46385976	46385998	11	+	27760321	HT29	viability after 10 days	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.09307129316379242	[389,304]	[399,341,474]	-1	hSpCas9	negative selection	5307382
46386242	46386264	11	+	27760321	HT29	viability after 10 days	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.6274438359621101	[618,482]	[1010,1003,1168]	8	hSpCas9	negative selection	5307383
46386414	46386436	11	+	27760321	HT29	viability after 10 days	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	0.48473436184758323	[855,667]	[1320,1461,1216]	6	hSpCas9	negative selection	5307384
46385860	46385882	11	-	27760321	MOLM13	viability	TCCACAAGCACCGGCCCGAGGG	CHRM4	ENSG00000180720	0.1801387330316283	[939,772]	[693,417]	1	hSpCas9	negative selection	5390843
46385875	46385897	11	+	27760321	MOLM13	viability	TTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	1.699683167581875	[441,465]	[801,865]	9	hSpCas9	negative selection	5390844
46385976	46385998	11	+	27760321	MOLM13	viability	TGCTGGGTTGGACAGGAACTGG	CHRM4	ENSG00000180720	-0.5757830629257688	[508,389]	[237,109]	-4	hSpCas9	negative selection	5390845
46386242	46386264	11	+	27760321	MOLM13	viability	CGCAGACCACGGCGCCCAGGGG	CHRM4	ENSG00000180720	0.49458558786983065	[750,618]	[642,455]	3	hSpCas9	negative selection	5390846
46386414	46386436	11	+	27760321	MOLM13	viability	CACGACAGTCACCAGGCTCAGG	CHRM4	ENSG00000180720	1.1371129714749246	[1012,855]	[1337,999]	7	hSpCas9	negative selection	5390847
46386149	46386172	11	+	27661255	K562	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.23795374735888508	[442,498]	[506,387]	7	dCas9-KRAB	negative selection	5470872
46386215	46386238	11	-	27661255	K562	viability	GTGGCTGGCCCTGGACTACGTGG	CHRM4	ENSG00000180720	-0.026502437340508278	[1618,1553]	[1364,1142]	-1	dCas9-KRAB	negative selection	5470873
46385405	46385428	11	-	27260156	BXPC3	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.45812751968395293	[745]	[931,1051,1291,1015]	8	hSpCas9	negative selection	5535712
46385126	46385149	11	+	27260156	BXPC3	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.03341975303081779	[779]	[705,764,779,962]	0	hSpCas9	negative selection	5535713
46385357	46385380	11	+	27260156	BXPC3	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.16025698207049377	[1145]	[1339,1152,1205,1700]	3	hSpCas9	negative selection	5535714
46386467	46386490	11	+	27260156	BXPC3	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.050838901589958185	[405]	[402,454,504,390]	1	hSpCas9	negative selection	5599985
46385874	46385897	11	+	27260156	BXPC3	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.29564409830055294	[241]	[270,300,263,421]	6	hSpCas9	negative selection	5599986
46385387	46385410	11	+	27260156	BXPC3	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.2761874663348012	[1355]	[1022,1221,1147,1311]	-6	hSpCas9	negative selection	5599987
46385405	46385428	11	-	27260156	A673	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.5141899944990753	[745]	[1271,1128,1264,1461]	9	hSpCas9	negative selection	5656963
46385126	46385149	11	+	27260156	A673	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.25776893213981256	[779]	[736,670,891,830]	-6	hSpCas9	negative selection	5656964
46385357	46385380	11	+	27260156	A673	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.24240030142184565	[1145]	[1790,1423,1462,1868]	6	hSpCas9	negative selection	5656965
46386467	46386490	11	+	27260156	A673	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.18750165836471702	[405]	[554,388,381,399]	-5	hSpCas9	negative selection	5721236
46385874	46385897	11	+	27260156	A673	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.258163013375432	[241]	[266,357,395,358]	6	hSpCas9	negative selection	5721237
46385387	46385410	11	+	27260156	A673	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.2541315963303976	[1355]	[1342,1235,1434,1448]	-6	hSpCas9	negative selection	5721238
46385405	46385428	11	-	27260156	A375	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6264204691168973	[745]	[1472,1488,1328,1130]	8	hSpCas9	negative selection	5778214
46385126	46385149	11	+	27260156	A375	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.18081866836721605	[779]	[903,978,791,587]	-3	hSpCas9	negative selection	5778215
46385357	46385380	11	+	27260156	A375	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.41785936126714085	[1145]	[1775,1856,1962,1583]	6	hSpCas9	negative selection	5778216
46386467	46386490	11	+	27260156	A375	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.06230972489701961	[405]	[535,444,441,397]	-1	hSpCas9	negative selection	5842487
46385874	46385897	11	+	27260156	A375	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.13124213362601156	[241]	[200,115,360,324]	-2	hSpCas9	negative selection	5842488
46385387	46385410	11	+	27260156	A375	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.04337510320462723	[1355]	[1689,1940,1583,1380]	0	hSpCas9	negative selection	5842489
46385405	46385428	11	-	27260156	COLO741	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.41540757428456665	[745]	[1378,1075,1357]	8	hSpCas9	negative selection	5899465
46385126	46385149	11	+	27260156	COLO741	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	0.061482629335264494	[779]	[1267,1071,813]	1	hSpCas9	negative selection	5899466
46385357	46385380	11	+	27260156	COLO741	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.2676175771674645	[1145]	[1661,1853,1759]	5	hSpCas9	negative selection	5899467
46386467	46386490	11	+	27260156	COLO741	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.39935278854106093	[405]	[889,548,632]	7	hSpCas9	negative selection	5963738
46385874	46385897	11	+	27260156	COLO741	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.061336278795669164	[241]	[280,321,357]	1	hSpCas9	negative selection	5963739
46385387	46385410	11	+	27260156	COLO741	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.08398586852300438	[1355]	[1619,1617,1658]	-2	hSpCas9	negative selection	5963740
46385405	46385428	11	-	27260156	CAL120	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6143782030418361	[745]	[2209,998,1176]	8	hSpCas9	negative selection	6020716
46385126	46385149	11	+	27260156	CAL120	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.1200697945780812	[779]	[1080,831,795]	-2	hSpCas9	negative selection	6020717
46385357	46385380	11	+	27260156	CAL120	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.21662833195022624	[1145]	[2000,1733,1293]	3	hSpCas9	negative selection	6020718
46386467	46386490	11	+	27260156	CAL120	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.3855536762230337	[405]	[790,467,738]	6	hSpCas9	negative selection	6084989
46385874	46385897	11	+	27260156	CAL120	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.3233819965662822	[241]	[234,297,188]	-5	hSpCas9	negative selection	6084990
46385387	46385410	11	+	27260156	CAL120	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.01640732318324445	[1355]	[1424,1778,1869]	0	hSpCas9	negative selection	6084991
46385405	46385428	11	-	27260156	CADOES1	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.7492359949156837	[745]	[1353,1232,1107,961]	9	hSpCas9	negative selection	6141967
46385126	46385149	11	+	27260156	CADOES1	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.04125414386621473	[779]	[557,465,982,816]	0	hSpCas9	negative selection	6141968
46385357	46385380	11	+	27260156	CADOES1	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.3296844669293377	[1145]	[1490,1343,1147,1375]	5	hSpCas9	negative selection	6141969
46386467	46386490	11	+	27260156	CADOES1	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.19093693309634371	[405]	[342,326,274,379]	-3	hSpCas9	negative selection	6206240
46385874	46385897	11	+	27260156	CADOES1	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.16717222685526878	[241]	[200,254,302,251]	3	hSpCas9	negative selection	6206241
46385387	46385410	11	+	27260156	CADOES1	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.06408428358218488	[1355]	[1131,1357,1179,1153]	-1	hSpCas9	negative selection	6206242
46385405	46385428	11	-	27260156	EWS502	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.7777811832136505	[745]	[1227,1226,1642,1338]	9	hSpCas9	negative selection	6263218
46385126	46385149	11	+	27260156	EWS502	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.06194357891980129	[779]	[766,811,823,759]	-1	hSpCas9	negative selection	6263219
46385357	46385380	11	+	27260156	EWS502	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.2841333470061891	[1145]	[1274,1487,1509,1671]	5	hSpCas9	negative selection	6263220
46386467	46386490	11	+	27260156	EWS502	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.3668314189808227	[405]	[304,218,482,335]	-6	hSpCas9	negative selection	6327491
46385874	46385897	11	+	27260156	EWS502	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.018495294592711153	[241]	[310,237,235,216]	0	hSpCas9	negative selection	6327492
46385387	46385410	11	+	27260156	EWS502	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.17345605742696213	[1355]	[911,1339,1256,1647]	-3	hSpCas9	negative selection	6327493
46385405	46385428	11	-	27260156	EW8	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.627116909015804	[745]	[1281,801,762,951]	9	hSpCas9	negative selection	6384469
46385126	46385149	11	+	27260156	EW8	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.47181115491260983	[779]	[425,438,469,480]	-7	hSpCas9	negative selection	6384470
46385357	46385380	11	+	27260156	EW8	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.287698646485705	[1145]	[1135,1280,1078,1045]	5	hSpCas9	negative selection	6384471
46386467	46386490	11	+	27260156	EW8	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.7137427796948353	[405]	[170,158,201,265]	-8	hSpCas9	negative selection	6448742
46385874	46385897	11	+	27260156	EW8	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.27746887016001887	[241]	[290,121,119,134]	-5	hSpCas9	negative selection	6448743
46385387	46385410	11	+	27260156	EW8	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.08387341331412013	[1355]	[1159,1108,891,1021]	-1	hSpCas9	negative selection	6448744
46385405	46385428	11	-	27260156	CORL105	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6337747302393184	[745]	[1319,1326,1586,1221]	9	hSpCas9	negative selection	6505720
46385126	46385149	11	+	27260156	CORL105	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.47029218291741876	[779]	[626,620,767,636]	-7	hSpCas9	negative selection	6505721
46385357	46385380	11	+	27260156	CORL105	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.37185060250347934	[1145]	[1890,1510,2310,1331]	7	hSpCas9	negative selection	6505722
46386467	46386490	11	+	27260156	CORL105	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.19494878415777087	[405]	[510,439,389,318]	-4	hSpCas9	negative selection	6569993
46385874	46385897	11	+	27260156	CORL105	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.06391920936966777	[241]	[363,212,267,242]	-1	hSpCas9	negative selection	6569994
46385387	46385410	11	+	27260156	CORL105	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.37271547978139363	[1355]	[1326,1100,1447,1068]	-6	hSpCas9	negative selection	6569995
46385405	46385428	11	-	27260156	HS294T	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6742256564501832	[745]	[417,473,406,560]	8	hSpCas9	negative selection	6626971
46385126	46385149	11	+	27260156	HS294T	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.47112967714667897	[779]	[235,206,197,228]	-6	hSpCas9	negative selection	6626972
46385357	46385380	11	+	27260156	HS294T	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.497790767572339	[1145]	[461,711,756,573]	6	hSpCas9	negative selection	6626973
46386467	46386490	11	+	27260156	HS294T	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.046873967327237226	[405]	[225,99,185,125]	0	hSpCas9	negative selection	6691244
46385874	46385897	11	+	27260156	HS294T	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.0472377242541836	[241]	[84,60,174,61]	0	hSpCas9	negative selection	6691245
46385387	46385410	11	+	27260156	HS294T	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.028905832419138466	[1355]	[405,527,719,488]	0	hSpCas9	negative selection	6691246
46385405	46385428	11	-	27260156	HCC44	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.4502469043326853	[745]	[1205,1000,1321,1128]	7	hSpCas9	negative selection	6748222
46385126	46385149	11	+	27260156	HCC44	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.01810568215796604	[779]	[925,645,1040,928]	0	hSpCas9	negative selection	6748223
46385357	46385380	11	+	27260156	HCC44	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.293451808838342	[1145]	[1565,1395,2120,1381]	5	hSpCas9	negative selection	6748224
46386467	46386490	11	+	27260156	HCC44	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.168020021880763	[405]	[305,456,528,345]	-3	hSpCas9	negative selection	6812495
46385874	46385897	11	+	27260156	HCC44	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.27960493389117225	[241]	[255,309,170,146]	-4	hSpCas9	negative selection	6812496
46385387	46385410	11	+	27260156	HCC44	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.3194454421840358	[1355]	[1288,748,1553,1436]	-5	hSpCas9	negative selection	6812497
46385405	46385428	11	-	27260156	G402	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.5617493498742376	[745]	[1635,1228,1115,1419]	7	hSpCas9	negative selection	6869473
46385126	46385149	11	+	27260156	G402	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.40787216414366373	[779]	[875,570,862,577]	-5	hSpCas9	negative selection	6869474
46385357	46385380	11	+	27260156	G402	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.35618305373954073	[1145]	[1443,2368,1607,1718]	4	hSpCas9	negative selection	6869475
46386467	46386490	11	+	27260156	G402	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.3646336425961054	[405]	[752,941,456,440]	4	hSpCas9	negative selection	6933746
46385874	46385897	11	+	27260156	G402	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.441831383072966	[241]	[603,359,269,395]	5	hSpCas9	negative selection	6933747
46385387	46385410	11	+	27260156	G402	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.20884251979611146	[1355]	[1762,1555,2059,2205]	2	hSpCas9	negative selection	6933748
46385405	46385428	11	-	27260156	L33	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.4132772130441864	[745]	[934,488,539,986]	8	hSpCas9	negative selection	6990724
46385126	46385149	11	+	27260156	L33	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.3419550953991916	[779]	[647,243,417,552]	-7	hSpCas9	negative selection	6990725
46385357	46385380	11	+	27260156	L33	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.01510568096981002	[1145]	[1103,487,727,1179]	0	hSpCas9	negative selection	6990726
46386467	46386490	11	+	27260156	L33	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.09931122062571476	[405]	[491,153,302,388]	2	hSpCas9	negative selection	7054997
46385874	46385897	11	+	27260156	L33	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.3001919531598113	[241]	[311,66,264,294]	6	hSpCas9	negative selection	7054998
46385387	46385410	11	+	27260156	L33	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.3858441090101703	[1355]	[1110,421,594,1060]	-7	hSpCas9	negative selection	7054999
46385405	46385428	11	-	27260156	K562	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.8094756426438263	[745]	[1017,1313,1088,1205]	8	hSpCas9	negative selection	7111975
46385126	46385149	11	+	27260156	K562	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	0.2891983071607076	[779]	[1194,672,1003,560]	3	hSpCas9	negative selection	7111976
46385357	46385380	11	+	27260156	K562	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.16074302399804452	[1145]	[1413,1128,1027,1008]	2	hSpCas9	negative selection	7111977
46386467	46386490	11	+	27260156	K562	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.006972990171988547	[405]	[235,516,296,390]	0	hSpCas9	negative selection	7176248
46385874	46385897	11	+	27260156	K562	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.29111714843549763	[241]	[425,211,96,318]	3	hSpCas9	negative selection	7176249
46385387	46385410	11	+	27260156	K562	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.06546054786693234	[1355]	[1536,1075,1581,892]	0	hSpCas9	negative selection	7176250
46385405	46385428	11	-	27260156	HT29	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.523741580315624	[745]	[1224,1366,1408,1214]	8	hSpCas9	negative selection	7233226
46385126	46385149	11	+	27260156	HT29	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.11731856994483492	[779]	[1052,833,923,709]	-2	hSpCas9	negative selection	7233227
46385357	46385380	11	+	27260156	HT29	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.26900237225224166	[1145]	[1779,1994,1496,1488]	5	hSpCas9	negative selection	7233228
46386467	46386490	11	+	27260156	HT29	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.2989054090151667	[405]	[643,719,548,532]	6	hSpCas9	negative selection	7297499
46385874	46385897	11	+	27260156	HT29	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.2232964786756817	[241]	[286,514,257,323]	4	hSpCas9	negative selection	7297500
46385387	46385410	11	+	27260156	HT29	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.2345942644303627	[1355]	[1274,1493,1672,1177]	-5	hSpCas9	negative selection	7297501
46385405	46385428	11	-	27260156	MHHES1	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.5407107925802257	[745]	[1356,1447,1283,889]	8	hSpCas9	negative selection	7354477
46385126	46385149	11	+	27260156	MHHES1	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.3668159964300571	[779]	[679,886,578,601]	-6	hSpCas9	negative selection	7354478
46385357	46385380	11	+	27260156	MHHES1	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.2564416860498222	[1145]	[1672,1702,1575,1274]	5	hSpCas9	negative selection	7354479
46386467	46386490	11	+	27260156	MHHES1	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.08792796808812695	[405]	[541,436,429,337]	-2	hSpCas9	negative selection	7418750
46385874	46385897	11	+	27260156	MHHES1	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.07832987711450146	[241]	[374,246,224,204]	-1	hSpCas9	negative selection	7418751
46385387	46385410	11	+	27260156	MHHES1	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.2710870120944362	[1355]	[1184,1483,1381,1046]	-5	hSpCas9	negative selection	7418752
46385405	46385428	11	-	27260156	MEWO	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.5935993977429284	[745]	[1121,978,1071]	9	hSpCas9	negative selection	7475728
46385126	46385149	11	+	27260156	MEWO	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	0.00038103828957614105	[779]	[993,686,559]	0	hSpCas9	negative selection	7475729
46385357	46385380	11	+	27260156	MEWO	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.16657136988090104	[1145]	[1402,1310,933]	3	hSpCas9	negative selection	7475730
46386467	46386490	11	+	27260156	MEWO	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.16959759614239692	[405]	[537,308,204]	-4	hSpCas9	negative selection	7540001
46385874	46385897	11	+	27260156	MEWO	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.2432588898605984	[241]	[134,166,260]	-5	hSpCas9	negative selection	7540002
46385387	46385410	11	+	27260156	MEWO	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.03339422612549647	[1355]	[1329,1243,1161]	0	hSpCas9	negative selection	7540003
46385405	46385428	11	-	27260156	LNCAPCLONEFGC	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6465071386118848	[745]	[883,1268,1077,991]	8	hSpCas9	negative selection	7596979
46385126	46385149	11	+	27260156	LNCAPCLONEFGC	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.30737089419732494	[779]	[489,542,806,481]	-5	hSpCas9	negative selection	7596980
46385357	46385380	11	+	27260156	LNCAPCLONEFGC	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.6115946056578159	[1145]	[1575,1502,1738,1553]	8	hSpCas9	negative selection	7596981
46386467	46386490	11	+	27260156	LNCAPCLONEFGC	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.12391189802860408	[405]	[380,263,486,492]	2	hSpCas9	negative selection	7661252
46385874	46385897	11	+	27260156	LNCAPCLONEFGC	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.19239888737284505	[241]	[176,325,221,268]	3	hSpCas9	negative selection	7661253
46385387	46385410	11	+	27260156	LNCAPCLONEFGC	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.025188419872038237	[1355]	[979,1168,1622,1292]	0	hSpCas9	negative selection	7661254
46385405	46385428	11	-	27260156	PANC0327	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.685114132420785	[745]	[923,847,1152,1352]	8	hSpCas9	negative selection	7718230
46385126	46385149	11	+	27260156	PANC0327	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.5156010992311468	[779]	[550,644,298,427]	-6	hSpCas9	negative selection	7718231
46385357	46385380	11	+	27260156	PANC0327	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.04227393337406227	[1145]	[1567,807,818,1070]	0	hSpCas9	negative selection	7718232
46386467	46386490	11	+	27260156	PANC0327	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.05583262213593834	[405]	[561,194,341,325]	-1	hSpCas9	negative selection	7782503
46385874	46385897	11	+	27260156	PANC0327	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.2989124055243342	[241]	[129,402,317,177]	4	hSpCas9	negative selection	7782504
46385387	46385410	11	+	27260156	PANC0327	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.45124070815556294	[1355]	[1064,863,795,815]	-6	hSpCas9	negative selection	7782505
46385405	46385428	11	-	27260156	NCIH2009	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.9455197876440178	[745]	[2263,1965,1839]	9	hSpCas9	negative selection	7839481
46385126	46385149	11	+	27260156	NCIH2009	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.2962106176554841	[779]	[1125,950,629]	-4	hSpCas9	negative selection	7839482
46385357	46385380	11	+	27260156	NCIH2009	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.2772920994987742	[1145]	[2047,1902,1888]	4	hSpCas9	negative selection	7839483
46386467	46386490	11	+	27260156	NCIH2009	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.15556663397449536	[405]	[408,569,526]	-2	hSpCas9	negative selection	7903754
46385874	46385897	11	+	27260156	NCIH2009	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.06431960867464748	[241]	[276,344,337]	-1	hSpCas9	negative selection	7903755
46385387	46385410	11	+	27260156	NCIH2009	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.050438871169344424	[1355]	[2083,1556,2272]	0	hSpCas9	negative selection	7903756
46385405	46385428	11	-	27260156	NCIH1373	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	1.2205319932854537	[745]	[3263,1071,1869,492]	9	hSpCas9	negative selection	7960732
46385126	46385149	11	+	27260156	NCIH1373	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.02416921835804764	[779]	[750,998,509,306]	0	hSpCas9	negative selection	7960733
46385357	46385380	11	+	27260156	NCIH1373	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.45264735508724474	[1145]	[1948,1512,1901,448]	4	hSpCas9	negative selection	7960734
46386467	46386490	11	+	27260156	NCIH1373	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.5008126196913962	[405]	[282,398,258,86]	-5	hSpCas9	negative selection	8025005
46385874	46385897	11	+	27260156	NCIH1373	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.025583356646890487	[241]	[415,81,264,91]	0	hSpCas9	negative selection	8025006
46385387	46385410	11	+	27260156	NCIH1373	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.01634523635873264	[1355]	[1454,1153,1438,567]	0	hSpCas9	negative selection	8025007
46385405	46385428	11	-	27260156	PATU8902	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.7716319023046616	[745]	[1465,1433,2197,1888]	7	hSpCas9	negative selection	8081983
46385126	46385149	11	+	27260156	PATU8902	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.46202892298380577	[779]	[849,493,987,758]	-4	hSpCas9	negative selection	8081984
46385357	46385380	11	+	27260156	PATU8902	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.7256864408786694	[1145]	[3556,2301,1832,3094]	7	hSpCas9	negative selection	8081985
46386467	46386490	11	+	27260156	PATU8902	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.25915758968839175	[405]	[648,392,157,804]	-3	hSpCas9	negative selection	8146256
46385874	46385897	11	+	27260156	PATU8902	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.5266734704888464	[241]	[138,151,330,294]	-5	hSpCas9	negative selection	8146257
46385387	46385410	11	+	27260156	PATU8902	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.35540391802992155	[1355]	[2040,3374,2157,2108]	3	hSpCas9	negative selection	8146258
46385405	46385428	11	-	27260156	PANC1	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6740928774670758	[745]	[985,1279,925,945]	9	hSpCas9	negative selection	8203234
46385126	46385149	11	+	27260156	PANC1	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.13529087343580415	[779]	[609,698,691,470]	-2	hSpCas9	negative selection	8203235
46385357	46385380	11	+	27260156	PANC1	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.1810199381820039	[1145]	[1094,1301,967,1116]	3	hSpCas9	negative selection	8203236
46386467	46386490	11	+	27260156	PANC1	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.14558338705341864	[405]	[291,417,418,411]	2	hSpCas9	negative selection	8267507
46385874	46385897	11	+	27260156	PANC1	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.1911689699189557	[241]	[159,453,187,195]	3	hSpCas9	negative selection	8267508
46385387	46385410	11	+	27260156	PANC1	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.18915031283357453	[1355]	[842,1323,1041,939]	-3	hSpCas9	negative selection	8267509
46385405	46385428	11	-	27260156	PANC0813	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.7892246824638571	[745]	[1628,1507,1499,1432]	9	hSpCas9	negative selection	8324485
46385126	46385149	11	+	27260156	PANC0813	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.3715080791183534	[779]	[866,646,623,707]	-5	hSpCas9	negative selection	8324486
46385357	46385380	11	+	27260156	PANC0813	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.2632094405368095	[1145]	[1922,1426,1510,1625]	4	hSpCas9	negative selection	8324487
46386467	46386490	11	+	27260156	PANC0813	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.058401963216097474	[405]	[667,448,353,527]	0	hSpCas9	negative selection	8388758
46385874	46385897	11	+	27260156	PANC0813	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.2500981479016059	[241]	[497,416,208,246]	4	hSpCas9	negative selection	8388759
46385387	46385410	11	+	27260156	PANC0813	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.08349797730608333	[1355]	[1494,1490,1523,1499]	-1	hSpCas9	negative selection	8388760
46385405	46385428	11	-	27260156	RDES	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6777103135125297	[745]	[1094,1297,1404,1780]	9	hSpCas9	negative selection	8445736
46385126	46385149	11	+	27260156	RDES	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.30863292290043964	[779]	[533,703,667,1062]	-5	hSpCas9	negative selection	8445737
46385357	46385380	11	+	27260156	RDES	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.35228745077273804	[1145]	[1426,1852,1525,1941]	5	hSpCas9	negative selection	8445738
46386467	46386490	11	+	27260156	RDES	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.5846041549932393	[405]	[298,261,385,295]	-7	hSpCas9	negative selection	8510009
46385874	46385897	11	+	27260156	RDES	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.08409430496158043	[241]	[213,248,217,390]	-1	hSpCas9	negative selection	8510010
46385387	46385410	11	+	27260156	RDES	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.12361448905068761	[1355]	[1185,1746,1913,2071]	2	hSpCas9	negative selection	8510011
46385405	46385428	11	-	27260156	PC3	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.4556839556507484	[745]	[557,903,1669,1335]	8	hSpCas9	negative selection	8566987
46385126	46385149	11	+	27260156	PC3	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.26097880856795924	[779]	[442,666,1191,519]	-5	hSpCas9	negative selection	8566988
46385357	46385380	11	+	27260156	PC3	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.04697245646230441	[1145]	[620,1144,1843,1532]	1	hSpCas9	negative selection	8566989
46386467	46386490	11	+	27260156	PC3	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.06159381928609595	[405]	[185,532,512,417]	-1	hSpCas9	negative selection	8631260
46385874	46385897	11	+	27260156	PC3	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.15268529901159533	[241]	[69,195,544,239]	-3	hSpCas9	negative selection	8631261
46385387	46385410	11	+	27260156	PC3	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.21233154294945034	[1355]	[737,1208,2095,1050]	-5	hSpCas9	negative selection	8631262
46385405	46385428	11	-	27260156	PATU8988T	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.7129380896041	[745]	[1495,1396,886,951]	9	hSpCas9	negative selection	8688238
46385126	46385149	11	+	27260156	PATU8988T	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.12008239469337567	[779]	[690,726,777,569]	-2	hSpCas9	negative selection	8688239
46385357	46385380	11	+	27260156	PATU8988T	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.33358880942146607	[1145]	[1520,1177,1350,1521]	6	hSpCas9	negative selection	8688240
46386467	46386490	11	+	27260156	PATU8988T	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.21174393149369278	[405]	[654,392,374,383]	3	hSpCas9	negative selection	8752511
46385874	46385897	11	+	27260156	PATU8988T	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.1637599244999186	[241]	[348,224,189,282]	3	hSpCas9	negative selection	8752512
46385387	46385410	11	+	27260156	PATU8988T	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.2983554582504211	[1355]	[1119,1201,772,1193]	-5	hSpCas9	negative selection	8752513
46385405	46385428	11	-	27260156	T47D	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.41423619448747995	[745]	[1060,1092,1155,1332]	8	hSpCas9	negative selection	8809489
46385126	46385149	11	+	27260156	T47D	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.4059462654549958	[779]	[663,662,715,701]	-7	hSpCas9	negative selection	8809490
46385357	46385380	11	+	27260156	T47D	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.2933470822220734	[1145]	[1689,1412,1630,1835]	6	hSpCas9	negative selection	8809491
46386467	46386490	11	+	27260156	T47D	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.10326505326553014	[405]	[498,597,453,472]	2	hSpCas9	negative selection	8873762
46385874	46385897	11	+	27260156	T47D	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.17059638104421315	[241]	[328,229,287,433]	3	hSpCas9	negative selection	8873763
46385387	46385410	11	+	27260156	T47D	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.22387967913220508	[1355]	[1436,1137,1557,1290]	-5	hSpCas9	negative selection	8873764
46385405	46385428	11	-	27260156	SU8686	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.6967613304727631	[745]	[1099,955,1298,1530]	9	hSpCas9	negative selection	8930740
46385126	46385149	11	+	27260156	SU8686	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.2935817361051153	[779]	[690,549,521,780]	-5	hSpCas9	negative selection	8930741
46385357	46385380	11	+	27260156	SU8686	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.0391737509378407	[1145]	[1134,1139,1214,1181]	0	hSpCas9	negative selection	8930742
46386467	46386490	11	+	27260156	SU8686	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.2667501161447501	[405]	[406,294,291,337]	-4	hSpCas9	negative selection	8995013
46385874	46385897	11	+	27260156	SU8686	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.17548953689905677	[241]	[192,297,231,380]	3	hSpCas9	negative selection	8995014
46385387	46385410	11	+	27260156	SU8686	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.3332302498957904	[1355]	[945,1017,930,1442]	-5	hSpCas9	negative selection	8995015
46385405	46385428	11	-	27260156	SKES1	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.4360343653732892	[745]	[1163,1289,923,728]	8	hSpCas9	negative selection	9051991
46385126	46385149	11	+	27260156	SKES1	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.023307170752942863	[779]	[861,834,708,680]	0	hSpCas9	negative selection	9051992
46385357	46385380	11	+	27260156	SKES1	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.3017457374602792	[1145]	[1510,1546,1269,1334]	6	hSpCas9	negative selection	9051993
46386467	46386490	11	+	27260156	SKES1	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	-0.13099237120484827	[405]	[458,338,370,320]	-3	hSpCas9	negative selection	9116264
46385874	46385897	11	+	27260156	SKES1	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.332471908991276	[241]	[323,425,283,207]	7	hSpCas9	negative selection	9116265
46385387	46385410	11	+	27260156	SKES1	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.24219958455130275	[1355]	[1204,1110,1166,1089]	-5	hSpCas9	negative selection	9116266
46385405	46385428	11	-	27260156	TOV112D	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.347357993313852	[745]	[915,1141,841,944]	6	hSpCas9	negative selection	9173242
46385126	46385149	11	+	27260156	TOV112D	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.08741344548458851	[779]	[774,935,667,616]	-2	hSpCas9	negative selection	9173243
46385357	46385380	11	+	27260156	TOV112D	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.19837156099898778	[1145]	[1274,1793,901,1405]	4	hSpCas9	negative selection	9173244
46386467	46386490	11	+	27260156	TOV112D	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.33135265522179136	[405]	[460,466,431,665]	6	hSpCas9	negative selection	9237515
46385874	46385897	11	+	27260156	TOV112D	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.0922491914340221	[241]	[172,391,115,262]	-2	hSpCas9	negative selection	9237516
46385387	46385410	11	+	27260156	TOV112D	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.06141315221516375	[1355]	[1462,1891,931,1081]	-1	hSpCas9	negative selection	9237517
46385405	46385428	11	-	27260156	TC71	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.3397129275509896	[745]	[890,996,1067,1097]	7	hSpCas9	negative selection	9294493
46385126	46385149	11	+	27260156	TC71	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.05631127111046308	[779]	[684,875,796,864]	-1	hSpCas9	negative selection	9294494
46385357	46385380	11	+	27260156	TC71	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.1590460329683705	[1145]	[1405,1362,1349,1366]	4	hSpCas9	negative selection	9294495
46386467	46386490	11	+	27260156	TC71	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.15529363291756168	[405]	[537,515,432,449]	4	hSpCas9	negative selection	9358766
46385874	46385897	11	+	27260156	TC71	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	-0.1744012723932441	[241]	[157,279,215,269]	-4	hSpCas9	negative selection	9358767
46385387	46385410	11	+	27260156	TC71	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.38883096107389625	[1355]	[922,1318,995,1216]	-8	hSpCas9	negative selection	9358768
46385405	46385428	11	-	27260156	TC32	viability	CGCCAGCATCGCTCGCAACCAGG	CHRM4	ENSG00000180720	0.8174971180515778	[745]	[1134,786,1532,1675]	9	hSpCas9	negative selection	9415744
46385126	46385149	11	+	27260156	TC32	viability	CAGTGCCGATGTTCCGATACTGG	CHRM4	ENSG00000180720	-0.3004328386572213	[779]	[557,448,814,622]	-5	hSpCas9	negative selection	9415745
46385357	46385380	11	+	27260156	TC32	viability	TTCGTGTCACTTTGCGCTCCCGG	CHRM4	ENSG00000180720	0.49402708222376535	[1145]	[1401,1065,1973,1817]	8	hSpCas9	negative selection	9415746
46386467	46386490	11	+	27260156	TC32	viability	CCACCGTCTCATAGCGATTGTGG	CHRM4	ENSG00000180720	0.13072968522275716	[405]	[417,232,463,621]	2	hSpCas9	negative selection	9480017
46385874	46385897	11	+	27260156	TC32	viability	CTTGTGGACTCGGCTGCGACTGG	CHRM4	ENSG00000180720	0.38804860848118494	[241]	[246,253,432,283]	6	hSpCas9	negative selection	9480018
46385387	46385410	11	+	27260156	TC32	viability	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.10128130618301467	[1355]	[1358,1243,1517,1329]	1	hSpCas9	negative selection	9480019
46385138	46385161	11	+	27869803	HPAFII	viability after 27 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.04892353949612893	[229]	[159,95,NaN]	0	hSpCas9	negative selection	9541616
46385387	46385410	11	+	27869803	HPAFII	viability after 27 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.6090190247840538	[215]	[8,128,NaN]	-4	hSpCas9	negative selection	9541617
46385680	46385703	11	+	27869803	HPAFII	viability after 27 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.397995417526803	[89]	[24,44,NaN]	-3	hSpCas9	negative selection	9541618
46385735	46385758	11	-	27869803	HPAFII	viability after 27 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.17919870651209124	[395]	[124,327,NaN]	1	hSpCas9	negative selection	9541619
46385987	46386010	11	+	27869803	HPAFII	viability after 27 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.04608761284174562	[305]	[277,53,NaN]	0	hSpCas9	negative selection	9541620
46386467	46386490	11	-	27869803	HPAFII	viability after 27 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	0.34094623267851687	[470]	[407,234,NaN]	2	hSpCas9	negative selection	9541621
46385138	46385161	11	+	27869803	HPAFII	viability after 15 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.18652771291066061	[229]	[305,161,NaN]	-2	hSpCas9	negative selection	9624065
46385387	46385410	11	+	27869803	HPAFII	viability after 15 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.044117986360037775	[215]	[226,223,NaN]	0	hSpCas9	negative selection	9624066
46385680	46385703	11	+	27869803	HPAFII	viability after 15 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	0.055984985498919615	[89]	[131,80,NaN]	0	hSpCas9	negative selection	9624067
46385735	46385758	11	-	27869803	HPAFII	viability after 15 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.1261490067761133	[395]	[453,470,NaN]	1	hSpCas9	negative selection	9624068
46385987	46386010	11	+	27869803	HPAFII	viability after 15 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.17773501565364785	[305]	[728,149,NaN]	2	hSpCas9	negative selection	9624069
46386467	46386490	11	-	27869803	HPAFII	viability after 15 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.5434807691326249	[470]	[617,178,NaN]	-5	hSpCas9	negative selection	9624070
46385138	46385161	11	+	27869803	ASPC1	viability after 36 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.5355075370571328	[615]	[464,250,248]	5	hSpCas9	negative selection	9706514
46385387	46385410	11	+	27869803	ASPC1	viability after 36 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.05541909693610124	[632]	[238,145,286]	0	hSpCas9	negative selection	9706515
46385680	46385703	11	+	27869803	ASPC1	viability after 36 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	1.1686272432214022	[223]	[97,450,9]	9	hSpCas9	negative selection	9706516
46385735	46385758	11	-	27869803	ASPC1	viability after 36 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	-0.8764243676460041	[1094]	[136,216,248]	-7	hSpCas9	negative selection	9706517
46385987	46386010	11	+	27869803	ASPC1	viability after 36 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.12272739915836976	[588]	[171,166,215]	-1	hSpCas9	negative selection	9706518
46386467	46386490	11	-	27869803	ASPC1	viability after 36 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.16317132157746217	[1199]	[225,678,231]	-2	hSpCas9	negative selection	9706519
46385138	46385161	11	+	27869803	PATU8988S	viability after 35 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.0965101489115332	[757]	[284,367,NaN]	1	hSpCas9	negative selection	9788963
46385387	46385410	11	+	27869803	PATU8988S	viability after 35 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.6769989720777729	[473]	[400,208,NaN]	7	hSpCas9	negative selection	9788964
46385680	46385703	11	+	27869803	PATU8988S	viability after 35 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-1.031958309101141	[286]	[68,43,NaN]	-7	hSpCas9	negative selection	9788965
46385735	46385758	11	-	27869803	PATU8988S	viability after 35 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.17442751307335058	[999]	[458,449,NaN]	2	hSpCas9	negative selection	9788966
46385987	46386010	11	+	27869803	PATU8988S	viability after 35 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	1.216552172515421	[498]	[484,448,NaN]	9	hSpCas9	negative selection	9788967
46386467	46386490	11	-	27869803	PATU8988S	viability after 35 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.5513711047162356	[1031]	[335,230,NaN]	-5	hSpCas9	negative selection	9788968
46385138	46385161	11	+	27869803	PATU8988S	viability after 31 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	0.15555136134865033	[757]	[227,474,NaN]	2	hSpCas9	negative selection	9871412
46385387	46385410	11	+	27869803	PATU8988S	viability after 31 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.8151853417794536	[473]	[321,345,NaN]	8	hSpCas9	negative selection	9871413
46385680	46385703	11	+	27869803	PATU8988S	viability after 31 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.4669124808568458	[286]	[73,93,NaN]	-5	hSpCas9	negative selection	9871414
46385735	46385758	11	-	27869803	PATU8988S	viability after 31 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.0579893593404166	[999]	[305,553,NaN]	0	hSpCas9	negative selection	9871415
46385987	46386010	11	+	27869803	PATU8988S	viability after 31 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	1.423145578284877	[498]	[460,625,NaN]	9	hSpCas9	negative selection	9871416
46386467	46386490	11	-	27869803	PATU8988S	viability after 31 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.6613105723546229	[1031]	[235,290,NaN]	-6	hSpCas9	negative selection	9871417
46385138	46385161	11	+	27869803	HPAFII	viability after 35 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.03622513497735219	[229]	[153,67,NaN]	0	hSpCas9	negative selection	9953861
46385387	46385410	11	+	27869803	HPAFII	viability after 35 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	-0.3709413344763566	[215]	[21,154,NaN]	-2	hSpCas9	negative selection	9953862
46385680	46385703	11	+	27869803	HPAFII	viability after 35 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.5886880414811695	[89]	[34,24,NaN]	-4	hSpCas9	negative selection	9953863
46385735	46385758	11	-	27869803	HPAFII	viability after 35 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.9891559542710973	[395]	[166,657,NaN]	6	hSpCas9	negative selection	9953864
46385987	46386010	11	+	27869803	HPAFII	viability after 35 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.3058701079973472	[305]	[169,74,NaN]	-2	hSpCas9	negative selection	9953865
46386467	46386490	11	-	27869803	HPAFII	viability after 35 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	0.4584221711105918	[470]	[408,235,NaN]	3	hSpCas9	negative selection	9953866
46385138	46385161	11	+	27869803	HPAFII	viability after 31 days	TCCGATACTGGCACAGCAGCAGG	CHRM4	ENSG00000180720	-0.3504425345152608	[229]	[128,70,NaN]	-2	hSpCas9	negative selection	10036310
46385387	46385410	11	+	27869803	HPAFII	viability after 31 days	TCTGCCGCTTCTTGCGCACCTGG	CHRM4	ENSG00000180720	0.020243983939947557	[215]	[20,233,NaN]	0	hSpCas9	negative selection	10036311
46385680	46385703	11	+	27869803	HPAFII	viability after 31 days	GAAGTGTCCTTATCAGCCACGGG	CHRM4	ENSG00000180720	-0.26028790753898723	[89]	[45,37,NaN]	-2	hSpCas9	negative selection	10036312
46385735	46385758	11	-	27869803	HPAFII	viability after 31 days	GCGCAATGGCAAGCTGGAGGAGG	CHRM4	ENSG00000180720	0.33965058409080306	[395]	[118,457,NaN]	2	hSpCas9	negative selection	10036313
46385987	46386010	11	+	27869803	HPAFII	viability after 31 days	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.04377205253920868	[305]	[246,78,NaN]	0	hSpCas9	negative selection	10036314
46386467	46386490	11	-	27869803	HPAFII	viability after 31 days	CCACAATCGCTATGAGACGGTGG	CHRM4	ENSG00000180720	-0.2812457040182613	[470]	[295,131,NaN]	-2	hSpCas9	negative selection	10036315
46386183	46386206	11	+	28162770	P31FUJ	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.13332569438351882	[134]	[173]	1	hSpCas9	negative selection	10133129
46385831	46385854	11	-	28162770	P31FUJ	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.1363047916406679	[366]	[473]	1	hSpCas9	negative selection	10133130
46385868	46385891	11	-	28162770	P31FUJ	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.044729856261806866	[236]	[269]	0	hSpCas9	negative selection	10133131
46385751	46385774	11	+	28162770	P31FUJ	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.705797250921478	[131]	[252]	7	hSpCas9	negative selection	10133132
46385384	46385407	11	-	28162770	P31FUJ	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.8826750130055572	[65]	[142]	8	hSpCas9	negative selection	10133133
46385253	46385276	11	-	28162770	P31FUJ	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	0.007024810258089875	[93]	[110]	0	hSpCas9	negative selection	10133134
46386149	46386172	11	+	28162770	P31FUJ	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.3590279497284574	[488]	[736]	4	hSpCas9	negative selection	10133135
46386057	46386080	11	+	28162770	P31FUJ	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.36792761216509406	[181]	[275]	4	hSpCas9	negative selection	10133136
46385987	46386010	11	+	28162770	P31FUJ	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.5469316753575613	[338]	[581]	6	hSpCas9	negative selection	10133137
46385937	46385960	11	+	28162770	P31FUJ	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	0.21971000028312826	[37]	[51]	2	hSpCas9	negative selection	10133138
46386183	46386206	11	+	28162770	TF1	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10302495
46385831	46385854	11	-	28162770	TF1	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	NaN	[NaN]	[298]	1	hSpCas9	negative selection	10302496
46385868	46385891	11	-	28162770	TF1	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	NaN	[NaN]	[221]	1	hSpCas9	negative selection	10302497
46385751	46385774	11	+	28162770	TF1	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10302498
46385384	46385407	11	-	28162770	TF1	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10302499
46385253	46385276	11	-	28162770	TF1	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10302500
46386149	46386172	11	+	28162770	TF1	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	NaN	[NaN]	[372]	1	hSpCas9	negative selection	10302501
46386057	46386080	11	+	28162770	TF1	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	NaN	[NaN]	[301]	1	hSpCas9	negative selection	10302502
46385987	46386010	11	+	28162770	TF1	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	NaN	[NaN]	[502]	1	hSpCas9	negative selection	10302503
46385937	46385960	11	+	28162770	TF1	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10302504
46386183	46386206	11	+	28162770	SKM1	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.10697865673647636	[52]	[86]	-1	hSpCas9	negative selection	10471861
46385831	46385854	11	-	28162770	SKM1	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	-0.5258696040119809	[78]	[96]	-4	hSpCas9	negative selection	10471862
46385868	46385891	11	-	28162770	SKM1	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.12338241550528205	[60]	[98]	-1	hSpCas9	negative selection	10471863
46385751	46385774	11	+	28162770	SKM1	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.8925960831157462	[38]	[127]	8	hSpCas9	negative selection	10471864
46385384	46385407	11	-	28162770	SKM1	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	-0.3129880505341478	[25]	[36]	-3	hSpCas9	negative selection	10471865
46385253	46385276	11	-	28162770	SKM1	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-0.7201220840027919	[40]	[43]	-5	hSpCas9	negative selection	10471866
46386149	46386172	11	+	28162770	SKM1	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.3422585093553465	[108]	[151]	-3	hSpCas9	negative selection	10471867
46386057	46386080	11	+	28162770	SKM1	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-0.7969107170591749	[56]	[57]	-5	hSpCas9	negative selection	10471868
46385987	46386010	11	+	28162770	SKM1	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.9766184140579901	[70]	[246]	8	hSpCas9	negative selection	10471869
46385937	46385960	11	+	28162770	SKM1	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-1.2370391973008492	[11]	[8]	-7	hSpCas9	negative selection	10471870
46386183	46386206	11	+	28162770	SKM1	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.10697865673647636	[52]	[86]	-1	hSpCas9	negative selection	10641227
46385831	46385854	11	-	28162770	SKM1	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	-0.5258696040119809	[78]	[96]	-4	hSpCas9	negative selection	10641228
46385868	46385891	11	-	28162770	SKM1	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.12338241550528205	[60]	[98]	-1	hSpCas9	negative selection	10641229
46385751	46385774	11	+	28162770	SKM1	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.8925960831157462	[38]	[127]	8	hSpCas9	negative selection	10641230
46385384	46385407	11	-	28162770	SKM1	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	-0.3129880505341478	[25]	[36]	-3	hSpCas9	negative selection	10641231
46385253	46385276	11	-	28162770	SKM1	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-0.7201220840027919	[40]	[43]	-5	hSpCas9	negative selection	10641232
46386149	46386172	11	+	28162770	SKM1	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.3422585093553465	[108]	[151]	-3	hSpCas9	negative selection	10641233
46386057	46386080	11	+	28162770	SKM1	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-0.7969107170591749	[56]	[57]	-5	hSpCas9	negative selection	10641234
46385987	46386010	11	+	28162770	SKM1	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.9766184140579901	[70]	[246]	8	hSpCas9	negative selection	10641235
46385937	46385960	11	+	28162770	SKM1	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-1.2370391973008492	[11]	[8]	-7	hSpCas9	negative selection	10641236
46386183	46386206	11	+	28162770	PL21	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.725697828012881	[156]	[112]	6	hSpCas9	negative selection	10810593
46385831	46385854	11	-	28162770	PL21	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	-0.7498197030110844	[339]	[87]	-5	hSpCas9	negative selection	10810594
46385868	46385891	11	-	28162770	PL21	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.02225280684712777	[230]	[98]	0	hSpCas9	negative selection	10810595
46385751	46385774	11	+	28162770	PL21	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	-1.0266312473577022	[219]	[46]	-6	hSpCas9	negative selection	10810596
46385384	46385407	11	-	28162770	PL21	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.853689200467889	[88]	[69]	7	hSpCas9	negative selection	10810597
46385253	46385276	11	-	28162770	PL21	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	0.4389264740764367	[99]	[58]	4	hSpCas9	negative selection	10810598
46386149	46386172	11	+	28162770	PL21	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.9709686605218103	[319]	[272]	7	hSpCas9	negative selection	10810599
46386057	46386080	11	+	28162770	PL21	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.695908385881021	[138]	[97]	6	hSpCas9	negative selection	10810600
46385987	46386010	11	+	28162770	PL21	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.21881293479290684	[245]	[91]	-1	hSpCas9	negative selection	10810601
46385937	46385960	11	+	28162770	PL21	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-1.844254504869134	[32]	[3]	-8	hSpCas9	negative selection	10810602
46386183	46386206	11	+	28162770	P31FUJ	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.13332569438351882	[134]	[173]	1	hSpCas9	negative selection	10979959
46385831	46385854	11	-	28162770	P31FUJ	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.1363047916406679	[366]	[473]	1	hSpCas9	negative selection	10979960
46385868	46385891	11	-	28162770	P31FUJ	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.044729856261806866	[236]	[269]	0	hSpCas9	negative selection	10979961
46385751	46385774	11	+	28162770	P31FUJ	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.705797250921478	[131]	[252]	7	hSpCas9	negative selection	10979962
46385384	46385407	11	-	28162770	P31FUJ	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.8826750130055572	[65]	[142]	8	hSpCas9	negative selection	10979963
46385253	46385276	11	-	28162770	P31FUJ	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	0.007024810258089875	[93]	[110]	0	hSpCas9	negative selection	10979964
46386149	46386172	11	+	28162770	P31FUJ	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.3590279497284574	[488]	[736]	4	hSpCas9	negative selection	10979965
46386057	46386080	11	+	28162770	P31FUJ	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.36792761216509406	[181]	[275]	4	hSpCas9	negative selection	10979966
46385987	46386010	11	+	28162770	P31FUJ	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.5469316753575613	[338]	[581]	6	hSpCas9	negative selection	10979967
46385937	46385960	11	+	28162770	P31FUJ	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	0.21971000028312826	[37]	[51]	2	hSpCas9	negative selection	10979968
46386183	46386206	11	+	28162770	OCIAML5	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.09937662440477435	[72]	[122]	0	hSpCas9	negative selection	11149325
46385831	46385854	11	-	28162770	OCIAML5	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.33696725352601986	[199]	[455]	3	hSpCas9	negative selection	11149326
46385868	46385891	11	-	28162770	OCIAML5	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	0.4484425403884599	[94]	[233]	4	hSpCas9	negative selection	11149327
46385751	46385774	11	+	28162770	OCIAML5	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.4374400463309878	[125]	[307]	4	hSpCas9	negative selection	11149328
46385384	46385407	11	-	28162770	OCIAML5	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.5264450523897329	[44]	[116]	4	hSpCas9	negative selection	11149329
46385253	46385276	11	-	28162770	OCIAML5	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-1.9713654992363412	[62]	[28]	-8	hSpCas9	negative selection	11149330
46386149	46386172	11	+	28162770	OCIAML5	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.4947047824820501	[369]	[473]	-3	hSpCas9	negative selection	11149331
46386057	46386080	11	+	28162770	OCIAML5	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-0.14157318805898195	[87]	[143]	-1	hSpCas9	negative selection	11149332
46385987	46386010	11	+	28162770	OCIAML5	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.23982320557665104	[226]	[346]	-2	hSpCas9	negative selection	11149333
46385937	46385960	11	+	28162770	OCIAML5	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-0.508112169646636	[25]	[32]	-4	hSpCas9	negative selection	11149334
46386183	46386206	11	+	28162770	EOL1	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.7156645897160843	[345]	[110]	-5	hSpCas9	negative selection	11318691
46385831	46385854	11	-	28162770	EOL1	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	-0.8220957364980255	[348]	[103]	-5	hSpCas9	negative selection	11318692
46385868	46385891	11	-	28162770	EOL1	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	0.37376238616746627	[437]	[298]	3	hSpCas9	negative selection	11318693
46385751	46385774	11	+	28162770	EOL1	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.5537100762022256	[299]	[231]	5	hSpCas9	negative selection	11318694
46385384	46385407	11	-	28162770	EOL1	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.13511475751019275	[139]	[80]	1	hSpCas9	negative selection	11318695
46385253	46385276	11	-	28162770	EOL1	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-0.8379529147028093	[189]	[55]	-5	hSpCas9	negative selection	11318696
46386149	46386172	11	+	28162770	EOL1	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.8703041782822385	[516]	[148]	-6	hSpCas9	negative selection	11318697
46386057	46386080	11	+	28162770	EOL1	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.7546227701282222	[188]	[167]	6	hSpCas9	negative selection	11318698
46385987	46386010	11	+	28162770	EOL1	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.22126530366061697	[380]	[233]	2	hSpCas9	negative selection	11318699
46385937	46385960	11	+	28162770	EOL1	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	0.133134393381952	[44]	[25]	1	hSpCas9	negative selection	11318700
46386183	46386206	11	+	28162770	MOLM13	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	2.9716371886805732	[203]	[1156]	9	hSpCas9	negative selection	11488057
46385831	46385854	11	-	28162770	MOLM13	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.30972169013251816	[442]	[396]	2	hSpCas9	negative selection	11488058
46385868	46385891	11	-	28162770	MOLM13	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	0.44495257026741997	[316]	[311]	3	hSpCas9	negative selection	11488059
46385751	46385774	11	+	28162770	MOLM13	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.8602068043233391	[271]	[356]	6	hSpCas9	negative selection	11488060
46385384	46385407	11	-	28162770	MOLM13	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.787646377390314	[132]	[165]	6	hSpCas9	negative selection	11488061
46385253	46385276	11	-	28162770	MOLM13	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	1.5489878068388168	[146]	[310]	9	hSpCas9	negative selection	11488062
46386149	46386172	11	+	28162770	MOLM13	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.1585275463482952	[405]	[262]	-1	hSpCas9	negative selection	11488063
46386057	46386080	11	+	28162770	MOLM13	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.1733194022776782	[221]	[180]	1	hSpCas9	negative selection	11488064
46385987	46386010	11	+	28162770	MOLM13	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	-0.9504838302975214	[432]	[161]	-5	hSpCas9	negative selection	11488065
46385937	46385960	11	+	28162770	MOLM13	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-3.4955847424303075	[77]	[4]	-8	hSpCas9	negative selection	11488066
46386183	46386206	11	+	28162770	HEL	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	-0.22720062743527	[211]	[115]	-2	hSpCas9	negative selection	11657423
46385831	46385854	11	-	28162770	HEL	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.5818098333580255	[265]	[254]	5	hSpCas9	negative selection	11657424
46385868	46385891	11	-	28162770	HEL	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	0.4746717767786268	[290]	[258]	4	hSpCas9	negative selection	11657425
46385751	46385774	11	+	28162770	HEL	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.044837275571702806	[279]	[184]	0	hSpCas9	negative selection	11657426
46385384	46385407	11	-	28162770	HEL	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	1.709507844213058	[94]	[198]	9	hSpCas9	negative selection	11657427
46385253	46385276	11	-	28162770	HEL	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-0.32771689238562784	[144]	[73]	-2	hSpCas9	negative selection	11657428
46386149	46386172	11	+	28162770	HEL	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.13884794192651873	[345]	[243]	1	hSpCas9	negative selection	11657429
46386057	46386080	11	+	28162770	HEL	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-0.505783692709731	[183]	[82]	-3	hSpCas9	negative selection	11657430
46385987	46386010	11	+	28162770	HEL	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.9856265455233655	[327]	[415]	8	hSpCas9	negative selection	11657431
46385937	46385960	11	+	28162770	HEL	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-2.387008511393695	[48]	[5]	-8	hSpCas9	negative selection	11657432
46386183	46386206	11	+	28162770	MV411	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.12911758359401415	[126]	[116]	1	hSpCas9	negative selection	11826789
46385831	46385854	11	-	28162770	MV411	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.3313998619271039	[266]	[282]	3	hSpCas9	negative selection	11826790
46385868	46385891	11	-	28162770	MV411	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	-0.6530267756663104	[223]	[119]	-4	hSpCas9	negative selection	11826791
46385751	46385774	11	+	28162770	MV411	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.5566064149547963	[158]	[196]	5	hSpCas9	negative selection	11826792
46385384	46385407	11	-	28162770	MV411	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	1.0603519981822802	[73]	[129]	8	hSpCas9	negative selection	11826793
46385253	46385276	11	-	28162770	MV411	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-0.04206906641220948	[131]	[107]	0	hSpCas9	negative selection	11826794
46386149	46386172	11	+	28162770	MV411	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.5786434592581485	[340]	[428]	5	hSpCas9	negative selection	11826795
46386057	46386080	11	+	28162770	MV411	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.13995312411637006	[194]	[180]	1	hSpCas9	negative selection	11826796
46385987	46386010	11	+	28162770	MV411	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.38197967416160294	[265]	[291]	3	hSpCas9	negative selection	11826797
46385937	46385960	11	+	28162770	MV411	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	0.9393152554204438	[25]	[41]	8	hSpCas9	negative selection	11826798
46386183	46386206	11	+	28162770	MONOMAC1	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.4711195891880011	[72]	[115]	4	hSpCas9	negative selection	11996155
46385831	46385854	11	-	28162770	MONOMAC1	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.4896883698125116	[186]	[300]	5	hSpCas9	negative selection	11996156
46385868	46385891	11	-	28162770	MONOMAC1	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	0.6074123438226395	[141]	[247]	6	hSpCas9	negative selection	11996157
46385751	46385774	11	+	28162770	MONOMAC1	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	-0.9340024412257597	[149]	[89]	-6	hSpCas9	negative selection	11996158
46385384	46385407	11	-	28162770	MONOMAC1	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	-0.004391769117157773	[55]	[63]	0	hSpCas9	negative selection	11996159
46385253	46385276	11	-	28162770	MONOMAC1	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	0.32002158915979884	[57]	[82]	3	hSpCas9	negative selection	11996160
46386149	46386172	11	+	28162770	MONOMAC1	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.054202068888098864	[220]	[243]	0	hSpCas9	negative selection	11996161
46386057	46386080	11	+	28162770	MONOMAC1	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	-0.5322210386491828	[81]	[64]	-4	hSpCas9	negative selection	11996162
46385987	46386010	11	+	28162770	MONOMAC1	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.7753068100375806	[157]	[309]	7	hSpCas9	negative selection	11996163
46385937	46385960	11	+	28162770	MONOMAC1	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-0.7819993477807099	[23]	[15]	-6	hSpCas9	negative selection	11996164
46386183	46386206	11	+	28162770	OCIAML2	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.5579393269546097	[24]	[203]	5	hSpCas9	negative selection	12165521
46385831	46385854	11	-	28162770	OCIAML2	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.4362607703663572	[45]	[344]	4	hSpCas9	negative selection	12165522
46385868	46385891	11	-	28162770	OCIAML2	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	0.6949562404758137	[36]	[331]	6	hSpCas9	negative selection	12165523
46385751	46385774	11	+	28162770	OCIAML2	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	1.1732263645325636	[21]	[274]	9	hSpCas9	negative selection	12165524
46385384	46385407	11	-	28162770	OCIAML2	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	0.2998883286350714	[16]	[115]	3	hSpCas9	negative selection	12165525
46385253	46385276	11	-	28162770	OCIAML2	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	1.10225984317842	[9]	[118]	9	hSpCas9	negative selection	12165526
46386149	46386172	11	+	28162770	OCIAML2	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	0.038029308165797526	[54]	[312]	0	hSpCas9	negative selection	12165527
46386057	46386080	11	+	28162770	OCIAML2	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.5091922928202085	[17]	[141]	5	hSpCas9	negative selection	12165528
46385987	46386010	11	+	28162770	OCIAML2	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.8398633745829176	[37]	[376]	7	hSpCas9	negative selection	12165529
46385937	46385960	11	+	28162770	OCIAML2	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-1.3637146213256495	[12]	[27]	-7	hSpCas9	negative selection	12165530
46386183	46386206	11	+	28162770	OCIAML3	viability	GATGAGAAGGTTCATGACGGAGG	CHRM4	ENSG00000180720	0.37797798350624046	[38]	[152]	3	hSpCas9	negative selection	12334887
46385831	46385854	11	-	28162770	OCIAML3	viability	GGAGAAGAAAGCCAAGACGCTGG	CHRM4	ENSG00000180720	0.6504110873422838	[64]	[307]	6	hSpCas9	negative selection	12334888
46385868	46385891	11	-	28162770	OCIAML3	viability	GCAGCCGAGTCCACAAGCACCGG	CHRM4	ENSG00000180720	1.0951294287514282	[68]	[444]	8	hSpCas9	negative selection	12334889
46385751	46385774	11	+	28162770	OCIAML3	viability	ATTGCGCAGCTCCTCCCGGGCGG	CHRM4	ENSG00000180720	0.39328130792628296	[56]	[225]	3	hSpCas9	negative selection	12334890
46385384	46385407	11	-	28162770	OCIAML3	viability	GGTGCGCAAGAAGCGGCAGATGG	CHRM4	ENSG00000180720	1.8080908032471823	[20]	[221]	9	hSpCas9	negative selection	12334891
46385253	46385276	11	-	28162770	OCIAML3	viability	GCTGCATCCCTGACACGGTGTGG	CHRM4	ENSG00000180720	-0.8439858933325106	[21]	[36]	-6	hSpCas9	negative selection	12334892
46386149	46386172	11	+	28162770	OCIAML3	viability	GCTTGGTGACGCAGAAGTAGCGG	CHRM4	ENSG00000180720	-0.6302278282369165	[120]	[235]	-5	hSpCas9	negative selection	12334893
46386057	46386080	11	+	28162770	OCIAML3	viability	GGCAGGCGCCCAGAGCACGAAGG	CHRM4	ENSG00000180720	0.18560229125053684	[29]	[102]	1	hSpCas9	negative selection	12334894
46385987	46386010	11	+	28162770	OCIAML3	viability	ACAGGAACTGGATGAAGCACTGG	CHRM4	ENSG00000180720	0.34306110394938005	[81]	[313]	3	hSpCas9	negative selection	12334895
46385937	46385960	11	+	28162770	OCIAML3	viability	AGGCAGGTAGAAGGCAGCAATGG	CHRM4	ENSG00000180720	-0.35696844302331376	[13]	[32]	-3	hSpCas9	negative selection	12334896