Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1198
• Symbol:CLK3
• Description:CDC like kinase 3

DataSource: http://genomecrispr.dkfz.de/#!/results/CLK3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
74619243	74619266	15	+	26472758	Jiyoye	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.6890399337534298	[123]	[57]	-5	hSpCas9	negative selection	33386
74629011	74629034	15	+	26472758	Jiyoye	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.5680212274935537	[172]	[43]	-7	hSpCas9	negative selection	33387
74620078	74620101	15	+	26472758	Jiyoye	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	0.42989545800595685	[62]	[63]	3	hSpCas9	negative selection	33388
74620200	74620223	15	-	26472758	Jiyoye	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	0.1212665094194928	[177]	[145]	0	hSpCas9	negative selection	33389
74622152	74622175	15	+	26472758	Jiyoye	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	0.30355275043171615	[100]	[93]	2	hSpCas9	negative selection	33390
74622513	74622536	15	+	26472758	Jiyoye	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.3160274934476781	[48]	[45]	2	hSpCas9	negative selection	33391
74625874	74625897	15	+	26472758	Jiyoye	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-2.2985392786758934	[136]	[20]	-8	hSpCas9	negative selection	33392
74627559	74627582	15	+	26472758	Jiyoye	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-0.6145196895934457	[66]	[32]	-4	hSpCas9	negative selection	33393
74627621	74627644	15	-	26472758	Jiyoye	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.6559033011175068	[373]	[178]	-5	hSpCas9	negative selection	33394
74628672	74628695	15	-	26472758	Jiyoye	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	33395
74619243	74619266	15	+	26472758	KBM7	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.055730369538734115	[314,388]	[166,156]	0	hSpCas9	negative selection	224504
74629011	74629034	15	+	26472758	KBM7	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-0.8686787004071064	[341,542]	[104,127]	-6	hSpCas9	negative selection	224505
74620078	74620101	15	+	26472758	KBM7	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-1.1906003527178575	[325,229]	[36,73]	-7	hSpCas9	negative selection	224506
74620200	74620223	15	-	26472758	KBM7	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.9139679962884856	[692,517]	[109,184]	-6	hSpCas9	negative selection	224507
74622152	74622175	15	+	26472758	KBM7	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-0.8160871501222328	[1012,693]	[173,269]	-6	hSpCas9	negative selection	224508
74622513	74622536	15	+	26472758	KBM7	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.02383448593255899	[215,161]	[160,19]	0	hSpCas9	negative selection	224509
74625874	74625897	15	+	26472758	KBM7	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-0.49261499904028483	[305,298]	[54,142]	-4	hSpCas9	negative selection	224510
74627559	74627582	15	+	26472758	KBM7	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-0.18846676485013508	[468,400]	[85,261]	-2	hSpCas9	negative selection	224511
74627621	74627644	15	-	26472758	KBM7	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.6083216192757828	[1638,1535]	[520,462]	-5	hSpCas9	negative selection	224512
74628672	74628695	15	-	26472758	KBM7	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-0.1798796302906629	[0,22]	[5,4]	-2	hSpCas9	negative selection	224513
74619243	74619266	15	+	26472758	Raji	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.28165875537229973	[219]	[41]	-2	hSpCas9	negative selection	415622
74629011	74629034	15	+	26472758	Raji	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-0.9187687524823691	[333]	[40]	-6	hSpCas9	negative selection	415623
74620078	74620101	15	+	26472758	Raji	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	0.37466741420875105	[112]	[33]	3	hSpCas9	negative selection	415624
74620200	74620223	15	-	26472758	Raji	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.48463372288150713	[409]	[67]	-4	hSpCas9	negative selection	415625
74622152	74622175	15	+	26472758	Raji	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	0.07577392885677747	[322]	[78]	0	hSpCas9	negative selection	415626
74622513	74622536	15	+	26472758	Raji	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.35204808326369763	[76]	[13]	-3	hSpCas9	negative selection	415627
74625874	74625897	15	+	26472758	Raji	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	1.4582906972327279	[68]	[43]	9	hSpCas9	negative selection	415628
74627559	74627582	15	+	26472758	Raji	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	0.6033410300360109	[155]	[54]	6	hSpCas9	negative selection	415629
74627621	74627644	15	-	26472758	Raji	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.24603710691729996	[740]	[144]	-2	hSpCas9	negative selection	415630
74628672	74628695	15	-	26472758	Raji	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-0.3951168051555842	[16]	[2]	-3	hSpCas9	negative selection	415631
74619243	74619266	15	+	26472758	K562	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.6997200971590178	[317]	[435]	6	hSpCas9	negative selection	606740
74629011	74629034	15	+	26472758	K562	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-0.8277310580893885	[491]	[233]	-5	hSpCas9	negative selection	606741
74620078	74620101	15	+	26472758	K562	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	0.1631788797062696	[346]	[327]	1	hSpCas9	negative selection	606742
74620200	74620223	15	-	26472758	K562	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	0.1876230226630488	[543]	[522]	1	hSpCas9	negative selection	606743
74622152	74622175	15	+	26472758	K562	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	0.07586445795754893	[525]	[467]	0	hSpCas9	negative selection	606744
74622513	74622536	15	+	26472758	K562	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.7676378786747068	[182]	[262]	6	hSpCas9	negative selection	606745
74625874	74625897	15	+	26472758	K562	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	0.1578310426703562	[205]	[193]	1	hSpCas9	negative selection	606746
74627559	74627582	15	+	26472758	K562	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	0.6354667310576413	[378]	[496]	5	hSpCas9	negative selection	606747
74627621	74627644	15	-	26472758	K562	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.2093883417769722	[1407]	[1027]	-1	hSpCas9	negative selection	606748
74628672	74628695	15	-	26472758	K562	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	0.28881284702490007	[63]	[65]	2	hSpCas9	negative selection	606749
74615662	74615685	15	-	26627737	DLD1	viability	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-1.0741092734063895	[359]	[125,0,33]	-7	hSpCas9	negative selection	791714
74619243	74619266	15	+	26627737	DLD1	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.5703907361975706	[462]	[119,196,311]	6	hSpCas9	negative selection	791715
74620218	74620241	15	-	26627737	DLD1	viability	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.7814932007801134	[1093]	[301,212,97]	-6	hSpCas9	negative selection	791716
74622179	74622202	15	-	26627737	DLD1	viability	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.18299133883781205	[410]	[309,90,48]	1	hSpCas9	negative selection	791717
74622513	74622536	15	+	26627737	DLD1	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.4519677644389565	[287]	[63,148,152]	4	hSpCas9	negative selection	791718
74624920	74624943	15	+	26627737	DLD1	viability	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.2568869424172826	[2039]	[707,722,840]	2	hSpCas9	negative selection	791719
74615662	74615685	15	-	26627737	GBM cells	viability after 5 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-1.2869526704256486	[181]	[45,33]	-9	hSpCas9	negative selection	874029
74619243	74619266	15	+	26627737	GBM cells	viability after 5 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.014111527332188123	[396]	[218,210]	0	hSpCas9	negative selection	874030
74620218	74620241	15	-	26627737	GBM cells	viability after 5 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.8610826879358615	[441]	[165,94]	-8	hSpCas9	negative selection	874031
74622179	74622202	15	-	26627737	GBM cells	viability after 5 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.03641739863562056	[229]	[154,97]	0	hSpCas9	negative selection	874032
74622513	74622536	15	+	26627737	GBM cells	viability after 5 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.7415437384271744	[211]	[65,69]	-8	hSpCas9	negative selection	874033
74624920	74624943	15	+	26627737	GBM cells	viability after 5 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.026888646956055418	[1098]	[596,559]	0	hSpCas9	negative selection	874034
74615662	74615685	15	-	26627737	GBM cells	viability after 13 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-0.7513429497834249	[181]	[72,46]	-7	hSpCas9	negative selection	956344
74619243	74619266	15	+	26627737	GBM cells	viability after 13 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.039883113713230944	[396]	[235,187]	0	hSpCas9	negative selection	956345
74620218	74620241	15	-	26627737	GBM cells	viability after 13 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.7035315369795685	[441]	[197,105]	-7	hSpCas9	negative selection	956346
74622179	74622202	15	-	26627737	GBM cells	viability after 13 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.2403209307055934	[229]	[142,150]	3	hSpCas9	negative selection	956347
74622513	74622536	15	+	26627737	GBM cells	viability after 13 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.9624552708724741	[211]	[47,67]	-8	hSpCas9	negative selection	956348
74624920	74624943	15	+	26627737	GBM cells	viability after 13 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.2760434152461131	[1098]	[492,491]	-3	hSpCas9	negative selection	956349
74615662	74615685	15	-	26627737	GBM cells	viability after 21 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-0.37563189658195617	[181]	[82,69]	-3	hSpCas9	negative selection	1038659
74619243	74619266	15	+	26627737	GBM cells	viability after 21 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.18417236654034352	[396]	[181,196]	-2	hSpCas9	negative selection	1038660
74620218	74620241	15	-	26627737	GBM cells	viability after 21 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-1.5723781651211657	[441]	[74,85]	-8	hSpCas9	negative selection	1038661
74622179	74622202	15	-	26627737	GBM cells	viability after 21 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.2788691919550126	[229]	[160,142]	3	hSpCas9	negative selection	1038662
74622513	74622536	15	+	26627737	GBM cells	viability after 21 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.3920859445099965	[211]	[104,71]	-4	hSpCas9	negative selection	1038663
74624920	74624943	15	+	26627737	GBM cells	viability after 21 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.06484468124807874	[1098]	[574,566]	0	hSpCas9	negative selection	1038664
74615662	74615685	15	-	26627737	RPE1	viability after 9 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	1.6692568141314035	[226]	[146,327]	8	hSpCas9	negative selection	1120974
74619243	74619266	15	+	26627737	RPE1	viability after 9 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.5478201192204071	[1301]	[225,346]	-4	hSpCas9	negative selection	1120975
74620218	74620241	15	-	26627737	RPE1	viability after 9 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.6008438178459521	[1943]	[423,371]	-4	hSpCas9	negative selection	1120976
74622179	74622202	15	-	26627737	RPE1	viability after 9 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	1.08172720611666	[596]	[347,456]	6	hSpCas9	negative selection	1120977
74622513	74622536	15	+	26627737	RPE1	viability after 9 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-1.2225890546898428	[1001]	[188,63]	-7	hSpCas9	negative selection	1120978
74624920	74624943	15	+	26627737	RPE1	viability after 9 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.43815525071555017	[3880]	[1650,1639]	3	hSpCas9	negative selection	1120979
74615662	74615685	15	-	26627737	RPE1	viability after 12 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	2.1618670287020616	[226]	[235,311]	9	hSpCas9	negative selection	1203289
74619243	74619266	15	+	26627737	RPE1	viability after 12 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.45944746109550466	[1301]	[233,275]	-3	hSpCas9	negative selection	1203290
74620218	74620241	15	-	26627737	RPE1	viability after 12 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.22309539352042052	[1943]	[411,484]	-1	hSpCas9	negative selection	1203291
74622179	74622202	15	-	26627737	RPE1	viability after 12 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	1.306480830169575	[596]	[420,370]	7	hSpCas9	negative selection	1203292
74622513	74622536	15	+	26627737	RPE1	viability after 12 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.6692389597940531	[1001]	[229,104]	-4	hSpCas9	negative selection	1203293
74624920	74624943	15	+	26627737	RPE1	viability after 12 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.4075437431463147	[3880]	[1452,1308]	2	hSpCas9	negative selection	1203294
74615662	74615685	15	-	26627737	RPE1	viability after 15 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	1.6795444185332402	[226]	[222,188]	8	hSpCas9	negative selection	1285604
74619243	74619266	15	+	26627737	RPE1	viability after 15 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.17765961318266854	[1301]	[289,359]	-1	hSpCas9	negative selection	1285605
74620218	74620241	15	-	26627737	RPE1	viability after 15 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.1660127519002048	[1943]	[425,551]	-1	hSpCas9	negative selection	1285606
74622179	74622202	15	-	26627737	RPE1	viability after 15 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	1.677805205020468	[596]	[550,529]	8	hSpCas9	negative selection	1285607
74622513	74622536	15	+	26627737	RPE1	viability after 15 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-1.4232531144620442	[1001]	[66,142]	-7	hSpCas9	negative selection	1285608
74624920	74624943	15	+	26627737	RPE1	viability after 15 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.32087037807639485	[3880]	[1550,1197]	2	hSpCas9	negative selection	1285609
74615662	74615685	15	-	26627737	RPE1	viability after 18 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	1.8712375977232414	[226]	[212,235]	8	hSpCas9	negative selection	1367919
74619243	74619266	15	+	26627737	RPE1	viability after 18 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.11105662519026538	[1301]	[305,345]	0	hSpCas9	negative selection	1367920
74620218	74620241	15	-	26627737	RPE1	viability after 18 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.0072251484941261435	[1943]	[288,770]	0	hSpCas9	negative selection	1367921
74622179	74622202	15	-	26627737	RPE1	viability after 18 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	1.8370324294437004	[596]	[607,540]	8	hSpCas9	negative selection	1367922
74622513	74622536	15	+	26627737	RPE1	viability after 18 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.38399294909608617	[1001]	[198,215]	-2	hSpCas9	negative selection	1367923
74624920	74624943	15	+	26627737	RPE1	viability after 18 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.34825510447900543	[3880]	[1356,1307]	2	hSpCas9	negative selection	1367924
74615662	74615685	15	-	26627737	HeLa	viability after 8 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	0.11066558025681228	[241]	[263,67,46]	1	hSpCas9	negative selection	1450234
74619243	74619266	15	+	26627737	HeLa	viability after 8 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	1.2011125899011061	[305]	[444,301,208]	8	hSpCas9	negative selection	1450235
74620218	74620241	15	-	26627737	HeLa	viability after 8 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.3773738464716578	[679]	[322,133,245]	-4	hSpCas9	negative selection	1450236
74622179	74622202	15	-	26627737	HeLa	viability after 8 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.042433435712876146	[369]	[151,170,170]	0	hSpCas9	negative selection	1450237
74622513	74622536	15	+	26627737	HeLa	viability after 8 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.3217278390782197	[391]	[198,202,232]	3	hSpCas9	negative selection	1450238
74624920	74624943	15	+	26627737	HeLa	viability after 8 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.18328552761045191	[1557]	[860,416,572]	-2	hSpCas9	negative selection	1450239
74615662	74615685	15	-	26627737	HeLa	viability after 12 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-1.3133305704891978	[241]	[21,60,34]	-8	hSpCas9	negative selection	1532549
74619243	74619266	15	+	26627737	HeLa	viability after 12 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	1.1993442914983516	[305]	[426,272,176]	8	hSpCas9	negative selection	1532550
74620218	74620241	15	-	26627737	HeLa	viability after 12 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.7783237596448404	[679]	[173,133,186]	-6	hSpCas9	negative selection	1532551
74622179	74622202	15	-	26627737	HeLa	viability after 12 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.6552355420914054	[369]	[211,85,439]	5	hSpCas9	negative selection	1532552
74622513	74622536	15	+	26627737	HeLa	viability after 12 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.09341508644447898	[391]	[228,126,168]	0	hSpCas9	negative selection	1532553
74624920	74624943	15	+	26627737	HeLa	viability after 12 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.13808241826658696	[1557]	[1042,673,421]	1	hSpCas9	negative selection	1532554
74615662	74615685	15	-	26627737	HeLa	viability after 15 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-0.5494637955072965	[241]	[53,45,104]	-5	hSpCas9	negative selection	1614864
74619243	74619266	15	+	26627737	HeLa	viability after 15 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	1.1539939611635506	[305]	[261,350,213]	7	hSpCas9	negative selection	1614865
74620218	74620241	15	-	26627737	HeLa	viability after 15 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-2.4437944127688573	[679]	[28,47,77]	-9	hSpCas9	negative selection	1614866
74622179	74622202	15	-	26627737	HeLa	viability after 15 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	-0.47101120301402705	[369]	[1,148,181]	-4	hSpCas9	negative selection	1614867
74622513	74622536	15	+	26627737	HeLa	viability after 15 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.36482422633803063	[391]	[29,61,293]	-3	hSpCas9	negative selection	1614868
74624920	74624943	15	+	26627737	HeLa	viability after 15 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.0430722685434457	[1557]	[528,864,560]	0	hSpCas9	negative selection	1614869
74615662	74615685	15	-	26627737	HeLa	viability after 18 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-0.483809932619472	[241]	[39,40,104]	-4	hSpCas9	negative selection	1697179
74619243	74619266	15	+	26627737	HeLa	viability after 18 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	1.1702147910341778	[305]	[175,297,213]	8	hSpCas9	negative selection	1697180
74620218	74620241	15	-	26627737	HeLa	viability after 18 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-2.432964399309106	[679]	[19,39,77]	-9	hSpCas9	negative selection	1697181
74622179	74622202	15	-	26627737	HeLa	viability after 18 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	-0.4469337825450351	[369]	[1,126,181]	-4	hSpCas9	negative selection	1697182
74622513	74622536	15	+	26627737	HeLa	viability after 18 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.3576548414380802	[391]	[23,47,293]	-3	hSpCas9	negative selection	1697183
74624920	74624943	15	+	26627737	HeLa	viability after 18 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.05016472281854645	[1557]	[362,713,560]	0	hSpCas9	negative selection	1697184
74615662	74615685	15	-	26627737	HCT116	viability after 6 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	2.114066241997617	[296]	[98,258]	8	hSpCas9	negative selection	1779494
74619243	74619266	15	+	26627737	HCT116	viability after 6 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.030658798138046783	[859]	[268,56]	0	hSpCas9	negative selection	1779495
74620218	74620241	15	-	26627737	HCT116	viability after 6 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	0.6660414074533743	[856]	[245,195]	3	hSpCas9	negative selection	1779496
74622179	74622202	15	-	26627737	HCT116	viability after 6 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	2.2442742804447953	[79]	[134,17]	9	hSpCas9	negative selection	1779497
74622513	74622536	15	+	26627737	HCT116	viability after 6 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.25489062682105523	[927]	[224,145]	1	hSpCas9	negative selection	1779498
74624920	74624943	15	+	26627737	HCT116	viability after 6 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.6564129271794754	[3176]	[870,740]	3	hSpCas9	negative selection	1779499
74615662	74615685	15	-	26627737	HCT116	viability after 8 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	1.0893252730444065	[88]	[132,112,67]	8	hSpCas9	negative selection	1861809
74619243	74619266	15	+	26627737	HCT116	viability after 8 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.5145404902938668	[481]	[187,282,87]	-6	hSpCas9	negative selection	1861810
74620218	74620241	15	-	26627737	HCT116	viability after 8 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	0.0334213070840117	[536]	[245,317,342]	0	hSpCas9	negative selection	1861811
74622179	74622202	15	-	26627737	HCT116	viability after 8 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	-0.7560394807920165	[440]	[139,98,191]	-7	hSpCas9	negative selection	1861812
74622513	74622536	15	+	26627737	HCT116	viability after 8 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.10616720005514285	[267]	[98,181,129]	-1	hSpCas9	negative selection	1861813
74624920	74624943	15	+	26627737	HCT116	viability after 8 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.8398155256706881	[923]	[930,709,1090]	7	hSpCas9	negative selection	1861814
74615662	74615685	15	-	26627737	HCT116	viability after 9 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	0.2638060844187169	[296]	[178,28]	2	hSpCas9	negative selection	1944124
74619243	74619266	15	+	26627737	HCT116	viability after 9 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.17064144306992896	[859]	[191,310]	1	hSpCas9	negative selection	1944125
74620218	74620241	15	-	26627737	HCT116	viability after 9 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	0.14980654208786165	[856]	[297,218]	1	hSpCas9	negative selection	1944126
74622179	74622202	15	-	26627737	HCT116	viability after 9 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	3.3359621594724302	[79]	[84,318]	9	hSpCas9	negative selection	1944127
74622513	74622536	15	+	26627737	HCT116	viability after 9 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.33404356891324	[927]	[171,215]	-2	hSpCas9	negative selection	1944128
74624920	74624943	15	+	26627737	HCT116	viability after 9 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.5171680839214896	[3176]	[1718,814]	4	hSpCas9	negative selection	1944129
74615662	74615685	15	-	26627737	HCT116	viability after 12 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	2.0064192014094013	[88]	[202,210,148]	9	hSpCas9	negative selection	2026439
74619243	74619266	15	+	26627737	HCT116	viability after 12 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.09180939511071462	[481]	[175,382,162]	-1	hSpCas9	negative selection	2026440
74620218	74620241	15	-	26627737	HCT116	viability after 12 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.21714642600033696	[536]	[172,347,215]	-2	hSpCas9	negative selection	2026441
74622179	74622202	15	-	26627737	HCT116	viability after 12 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.10408952946011973	[440]	[154,184,413]	1	hSpCas9	negative selection	2026442
74622513	74622536	15	+	26627737	HCT116	viability after 12 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.4004035014953711	[267]	[134,220,206]	4	hSpCas9	negative selection	2026443
74624920	74624943	15	+	26627737	HCT116	viability after 12 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.5053520293362253	[923]	[757,697,605]	5	hSpCas9	negative selection	2026444
74615662	74615685	15	-	26627737	HCT116	viability after 15 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	2.1060706383049093	[88]	[319,272,80]	9	hSpCas9	negative selection	2108754
74619243	74619266	15	+	26627737	HCT116	viability after 15 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.10492202248188132	[481]	[292,425,174]	1	hSpCas9	negative selection	2108755
74620218	74620241	15	-	26627737	HCT116	viability after 15 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.08798228441767109	[536]	[277,385,205]	-1	hSpCas9	negative selection	2108756
74622179	74622202	15	-	26627737	HCT116	viability after 15 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.12719330439048404	[440]	[169,216,427]	1	hSpCas9	negative selection	2108757
74622513	74622536	15	+	26627737	HCT116	viability after 15 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.7814902189478732	[267]	[280,193,319]	6	hSpCas9	negative selection	2108758
74624920	74624943	15	+	26627737	HCT116	viability after 15 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.6409317357359292	[923]	[1052,726,730]	6	hSpCas9	negative selection	2108759
74615662	74615685	15	-	26627737	HCT116	viability after 18 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	1.6006766514084616	[88]	[215,90,84]	9	hSpCas9	negative selection	2191069
74619243	74619266	15	+	26627737	HCT116	viability after 18 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.47553801374809057	[481]	[322,452,180]	4	hSpCas9	negative selection	2191070
74620218	74620241	15	-	26627737	HCT116	viability after 18 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.5049140619035367	[536]	[199,148,202]	-4	hSpCas9	negative selection	2191071
74622179	74622202	15	-	26627737	HCT116	viability after 18 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.06045612236379472	[440]	[217,163,291]	0	hSpCas9	negative selection	2191072
74622513	74622536	15	+	26627737	HCT116	viability after 18 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.6745235117597815	[267]	[203,39,395]	5	hSpCas9	negative selection	2191073
74624920	74624943	15	+	26627737	HCT116	viability after 18 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.6496517034264877	[923]	[584,802,707]	5	hSpCas9	negative selection	2191074
74619223	74619246	15	-	24336569	HL60	viability	TCAGGTACGGGTCTGGTTCAGGG	CLK3	ENSG00000179335	0.9691619724410718	[363]	[1507]	7	hSpCas9	negative selection	2258128
74619230	74619253	15	-	24336569	HL60	viability	CGGTAGCTCAGGTACGGGTCTGG	CLK3	ENSG00000179335	1.2154899544802527	[302]	[1488]	8	hSpCas9	negative selection	2258129
74619235	74619258	15	-	24336569	HL60	viability	TCCATCGGTAGCTCAGGTACGGG	CLK3	ENSG00000179335	-1.464946866032895	[813]	[623]	-8	hSpCas9	negative selection	2258130
74619240	74619263	15	+	24336569	HL60	viability	ACCTGAGCTACCGATGGAAGAGG	CLK3	ENSG00000179335	0.4985912693718513	[588]	[1760]	4	hSpCas9	negative selection	2258131
74619246	74619269	15	+	24336569	HL60	viability	GCTACCGATGGAAGAGGAGGAGG	CLK3	ENSG00000179335	1.0273933134096755	[1192]	[5145]	7	hSpCas9	negative selection	2258132
74619258	74619281	15	+	24336569	HL60	viability	AGAGGAGGAGGTCCTACAGTCGG	CLK3	ENSG00000179335	0.7369001281280894	[1062]	[3748]	6	hSpCas9	negative selection	2258133
74619269	74619292	15	+	24336569	HL60	viability	TCCTACAGTCGGGAACATGAAGG	CLK3	ENSG00000179335	0.46675697548177064	[1086]	[3178]	4	hSpCas9	negative selection	2258134
74619294	74619317	15	+	24336569	HL60	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.9555594100899548	[778]	[3196]	7	hSpCas9	negative selection	2258135
74619325	74619348	15	-	24336569	HL60	viability	TTCTGGACCGAGATCTTCGTGGG	CLK3	ENSG00000179335	-0.017848001332924635	[853]	[1784]	0	hSpCas9	negative selection	2258136
74620009	74620032	15	-	24336569	HL60	viability	TCTGGTAGGGCAGGCGGTCATGG	CLK3	ENSG00000179335	0.9110730821424828	[532]	[2120]	7	hSpCas9	negative selection	2258137
74619223	74619246	15	-	24336569	KBM7	viability	TCAGGTACGGGTCTGGTTCAGGG	CLK3	ENSG00000179335	0.5013681373265348	[301]	[1165]	4	hSpCas9	negative selection	2325305
74619230	74619253	15	-	24336569	KBM7	viability	CGGTAGCTCAGGTACGGGTCTGG	CLK3	ENSG00000179335	0.7486530331175107	[476]	[2185]	6	hSpCas9	negative selection	2325306
74619235	74619258	15	-	24336569	KBM7	viability	TCCATCGGTAGCTCAGGTACGGG	CLK3	ENSG00000179335	0.8566197039061747	[261]	[1293]	7	hSpCas9	negative selection	2325307
74619240	74619263	15	+	24336569	KBM7	viability	ACCTGAGCTACCGATGGAAGAGG	CLK3	ENSG00000179335	-0.2507026489384816	[765]	[1755]	-2	hSpCas9	negative selection	2325308
74619246	74619269	15	+	24336569	KBM7	viability	GCTACCGATGGAAGAGGAGGAGG	CLK3	ENSG00000179335	-0.23923728596540994	[1473]	[3405]	-2	hSpCas9	negative selection	2325309
74619258	74619281	15	+	24336569	KBM7	viability	AGAGGAGGAGGTCCTACAGTCGG	CLK3	ENSG00000179335	-0.004224322315873552	[926]	[2520]	0	hSpCas9	negative selection	2325310
74619269	74619292	15	+	24336569	KBM7	viability	TCCTACAGTCGGGAACATGAAGG	CLK3	ENSG00000179335	0.23041824880575112	[1210]	[3874]	2	hSpCas9	negative selection	2325311
74619294	74619317	15	+	24336569	KBM7	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.3503024405381032	[766]	[1640]	-3	hSpCas9	negative selection	2325312
74619325	74619348	15	-	24336569	KBM7	viability	TTCTGGACCGAGATCTTCGTGGG	CLK3	ENSG00000179335	-0.1700206186540162	[732]	[1776]	-1	hSpCas9	negative selection	2325313
74620009	74620032	15	-	24336569	KBM7	viability	TCTGGTAGGGCAGGCGGTCATGG	CLK3	ENSG00000179335	-0.19261999393869234	[850]	[2030]	-2	hSpCas9	negative selection	2325314
74608238	74608261	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAACTGCAGAGACTCCAGAGG	CLK3	ENSG00000179335	-1.2702398823978414	[136,9]	[10,0]	-7	dCas9-VP64	positive selection	2434365
74608270	74608293	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTCAGGGCAACTGCCAGCCGG	CLK3	ENSG00000179335	-0.6828853537329482	[154,16]	[16,4]	-3	dCas9-VP64	positive selection	2434366
74608195	74608218	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGGAGACAGTGCCCACCTGG	CLK3	ENSG00000179335	2.6848861449169092	[5,1]	[8,1]	8	dCas9-VP64	positive selection	2434367
74608238	74608261	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAACTGCAGAGACTCCAGAGG	CLK3	ENSG00000179335	-0.5933036729556326	[107,148]	[18,34]	-6	dCas9-VP64	positive selection	2529620
74608270	74608293	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTCAGGGCAACTGCCAGCCGG	CLK3	ENSG00000179335	-0.6739323890917961	[114,35]	[18,11]	-6	dCas9-VP64	positive selection	2529621
74608195	74608218	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGGAGACAGTGCCCACCTGG	CLK3	ENSG00000179335	0.13611475586296007	[125,42]	[49,11]	1	dCas9-VP64	positive selection	2529622
74619296	74619319	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGCGATACCCGTCCCGAAGGG	CLK3	ENSG00000179335	-0.18521478912313755	[2,2]	[2,0]	-3	hSpCas9	positive selection	2979819
74622154	74622177	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGTGGAAGATGACAAGGAGGG	CLK3	ENSG00000179335	-0.4396572098941108	[3,4]	[1,2]	-6	hSpCas9	positive selection	2979820
74620060	74620083	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACATACCGGTGTGAAGAGCGG	CLK3	ENSG00000179335	-0.6339342477323353	[3,6]	[2,2]	-7	hSpCas9	positive selection	2979821
74619271	74619294	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTACAGTCGGGAACATGAAGGG	CLK3	ENSG00000179335	-0.45143287693724826	[3,3]	[2,1]	-6	hSpCas9	positive selection	2979822
74619296	74619319	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGCGATACCCGTCCCGAAGGG	CLK3	ENSG00000179335	-0.1278027662045927	[2,2]	[2,0]	-2	hSpCas9	positive selection	3047677
74622154	74622177	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGTGGAAGATGACAAGGAGGG	CLK3	ENSG00000179335	0.2667210691352036	[3,3]	[4,2]	5	hSpCas9	positive selection	3047678
74620060	74620083	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACATACCGGTGTGAAGAGCGG	CLK3	ENSG00000179335	-0.3423704516586164	[3,3]	[2,0]	-5	hSpCas9	positive selection	3047679
74619271	74619294	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTACAGTCGGGAACATGAAGGG	CLK3	ENSG00000179335	0.2022367854229674	[3,3]	[2,2]	3	hSpCas9	positive selection	3047680
74627428	74627451		-	24336571	A375	resistance to PLX after 7 days	ATACCTTGTGCTCATTGTAGAGG	CLK3	ENSG00000179335	-0.22762425526171073	[12,13]	[10,10]	-7	hSpCas9	positive selection	3106120
74619294	74619317		+	24336571	A375	resistance to PLX after 7 days	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.10644656881606618	[20,19]	[20,21]	3	hSpCas9	positive selection	3106121
74627428	74627451		-	24336571	A375	resistance to PLX after 14 days	ATACCTTGTGCTCATTGTAGAGG	CLK3	ENSG00000179335	-0.6915169661542538	[10,12]	[2,3]	-7	hSpCas9	positive selection	3163913
74619294	74619317		+	24336571	A375	resistance to PLX after 14 days	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.35827021731378483	[27,18]	[15,11]	3	hSpCas9	positive selection	3163914
74627428	74627451		-	24336571	A375	viability after 7 days	ATACCTTGTGCTCATTGTAGAGG	CLK3	ENSG00000179335	-0.5613435521095016	[20]	[12,13]	-7	hSpCas9	negative selection	3221706
74619294	74619317		+	24336571	A375	viability after 7 days	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.41491607044962686	[27]	[20,19]	-5	hSpCas9	negative selection	3221707
74627428	74627451		-	24336571	A375	viability after 14 days	ATACCTTGTGCTCATTGTAGAGG	CLK3	ENSG00000179335	-0.6449208924576628	[20]	[10,12]	-7	hSpCas9	negative selection	3279499
74619294	74619317		+	24336571	A375	viability after 14 days	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.16993220144896037	[27]	[27,18]	-2	hSpCas9	negative selection	3279500
74619294	74619317	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.13425298904951358	[123,154]	[0,0]	0	hSpCas9	positive selection	3343572
74627637	74627660	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	-0.19544663764442688	[203,145]	[0,0]	-1	hSpCas9	positive selection	3343573
74627624	74627647	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.4986522414818658	[240,190]	[0,0]	-3	hSpCas9	positive selection	3343574
74619234	74619257	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.7925223380047265	[264,264]	[0,0]	-5	hSpCas9	positive selection	3362792
74627425	74627448	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.9374306429764127	[292,292]	[0,0]	-6	hSpCas9	positive selection	3362793
74627374	74627397	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	-0.15206472469186658	[169,169]	[0,0]	-1	hSpCas9	positive selection	3362794
74619295	74619318	15	+	26780180	HT29	viability (Avana library 4 designs)	ACTGCGATACCCGTCCCGAAGGG	CLK3	ENSG00000179335	1.43995729035578	[]	[]	5	hSpCas9	negative selection	3416252
74622153	74622176	15	+	26780180	HT29	viability (Avana library 4 designs)	AGTGTGGAAGATGACAAGGAGGG	CLK3	ENSG00000179335	1.29537140906283	[]	[]	5	hSpCas9	negative selection	3416253
74620059	74620082	15	+	26780180	HT29	viability (Avana library 4 designs)	ATACATACCGGTGTGAAGAGCGG	CLK3	ENSG00000179335	0.142737271933704	[]	[]	0	hSpCas9	negative selection	3416254
74619270	74619293	15	+	26780180	HT29	viability (Avana library 4 designs)	CCTACAGTCGGGAACATGAAGGG	CLK3	ENSG00000179335	0.282449002026878	[]	[]	1	hSpCas9	negative selection	3416255
74620059	74620082	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATACATACCGGTGTGAAGAGCGG	CLK3	ENSG00000179335	2.35761283500695	[]	[]	3	hSpCas9	negative selection	3493695
74619295	74619318	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCGATACCCGTCCCGAAGGG	CLK3	ENSG00000179335	3.23886506440644	[]	[]	5	hSpCas9	negative selection	3493696
74619270	74619293	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACAGTCGGGAACATGAAGGG	CLK3	ENSG00000179335	2.16994555980539	[]	[]	3	hSpCas9	negative selection	3493697
74622153	74622176	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGTGGAAGATGACAAGGAGGG	CLK3	ENSG00000179335	0.373785404046602	[]	[]	0	hSpCas9	negative selection	3493698
74619324	74619347	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGACCGAGATCTTCGTGGGG	CLK3	ENSG00000179335	-0.72161170825741	[]	[]	-1	hSpCas9	negative selection	3493699
74619250	74619273	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGACCTCCTCCTCTTCCATCGG	CLK3	ENSG00000179335	1.09981161864517	[]	[]	1	hSpCas9	negative selection	3493700
74620059	74620082	15	+	26780180	A375	viability (Avana lentiGuide)	ATACATACCGGTGTGAAGAGCGG	CLK3	ENSG00000179335	-4.31086049705443	[]	[]	-7	hSpCas9	negative selection	3602354
74619295	74619318	15	+	26780180	A375	viability (Avana lentiGuide)	ACTGCGATACCCGTCCCGAAGGG	CLK3	ENSG00000179335	0.445712496619909	[]	[]	0	hSpCas9	negative selection	3602355
74619270	74619293	15	+	26780180	A375	viability (Avana lentiGuide)	CCTACAGTCGGGAACATGAAGGG	CLK3	ENSG00000179335	-2.7956843014457	[]	[]	-5	hSpCas9	negative selection	3602356
74622153	74622176	15	+	26780180	A375	viability (Avana lentiGuide)	AGTGTGGAAGATGACAAGGAGGG	CLK3	ENSG00000179335	7.96138439709513	[]	[]	6	hSpCas9	negative selection	3602357
74619324	74619347	15	-	26780180	A375	viability (Avana lentiGuide)	TCTGGACCGAGATCTTCGTGGGG	CLK3	ENSG00000179335	5.89009795792227	[]	[]	5	hSpCas9	negative selection	3602358
74619250	74619273	15	-	26780180	A375	viability (Avana lentiGuide)	AGGACCTCCTCCTCTTCCATCGG	CLK3	ENSG00000179335	2.66755319825179	[]	[]	3	hSpCas9	negative selection	3602359
74620059	74620082	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACATACCGGTGTGAAGAGCGG	CLK3	ENSG00000179335	0.030296469698386577	[5]	[5,5]	0	hSpCas9	positive selection	3711013
74619295	74619318	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCGATACCCGTCCCGAAGGG	CLK3	ENSG00000179335	0.10193491945044733	[4]	[5,4]	2	hSpCas9	positive selection	3711014
74619270	74619293	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACAGTCGGGAACATGAAGGG	CLK3	ENSG00000179335	-0.1153734241528322	[4]	[5,2]	-2	hSpCas9	positive selection	3711015
74622153	74622176	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGTGGAAGATGACAAGGAGGG	CLK3	ENSG00000179335	-0.12880663897214154	[6]	[5,4]	-2	hSpCas9	positive selection	3711016
74619324	74619347	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGACCGAGATCTTCGTGGGG	CLK3	ENSG00000179335	0.023913755551958404	[6]	[6,5]	0	hSpCas9	positive selection	3711017
74619250	74619273	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGACCTCCTCCTCTTCCATCGG	CLK3	ENSG00000179335	-0.2006500516749924	[5]	[5,3]	-3	hSpCas9	positive selection	3711018
74620059	74620082	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACATACCGGTGTGAAGAGCGG	CLK3	ENSG00000179335	-0.16594190954068436	[5]	[2,5]	-2	hSpCas9	positive selection	3819620
74619295	74619318	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCGATACCCGTCCCGAAGGG	CLK3	ENSG00000179335	-0.7748198450733411	[4]	[2,0]	-7	hSpCas9	positive selection	3819621
74619270	74619293	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACAGTCGGGAACATGAAGGG	CLK3	ENSG00000179335	-0.8054815524863947	[4]	[2,0]	-7	hSpCas9	positive selection	3819622
74622153	74622176	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGTGGAAGATGACAAGGAGGG	CLK3	ENSG00000179335	-0.09230085687367198	[6]	[3,5]	-1	hSpCas9	positive selection	3819623
74619324	74619347	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGACCGAGATCTTCGTGGGG	CLK3	ENSG00000179335	-0.035203003238719	[7]	[5,6]	0	hSpCas9	positive selection	3819624
74619250	74619273	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGACCTCCTCCTCTTCCATCGG	CLK3	ENSG00000179335	-0.25196241949455	[6]	[4,3]	-3	hSpCas9	positive selection	3819625
74627425	74627448	15	+	26780180	A375	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.645204394390364	[]	[]	2	hSpCas9	negative selection	3927616
74619234	74619257	15	+	26780180	A375	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	1.73651444374808	[]	[]	9	hSpCas9	negative selection	3927617
74627624	74627647	15	-	26780180	A375	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.872073369560749	[]	[]	3	hSpCas9	negative selection	3927618
74627637	74627660	15	+	26780180	A375	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	1.20077273812992	[]	[]	6	hSpCas9	negative selection	3927619
74619294	74619317	15	+	26780180	A375	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	1.43082420924621	[]	[]	8	hSpCas9	negative selection	3927620
74627374	74627397	15	-	26780180	A375	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.189110279427445	[]	[]	0	hSpCas9	negative selection	3927621
74627425	74627448	15	+	26780180	HT29	viability (GeCKOv2 library)	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.578532864277728	[]	[]	2	hSpCas9	negative selection	4035582
74619234	74619257	15	+	26780180	HT29	viability (GeCKOv2 library)	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	1.43489117427489	[]	[]	7	hSpCas9	negative selection	4035583
74627624	74627647	15	-	26780180	HT29	viability (GeCKOv2 library)	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	1.12338464800589	[]	[]	5	hSpCas9	negative selection	4035584
74627637	74627660	15	+	26780180	HT29	viability (GeCKOv2 library)	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.417094796291008	[]	[]	1	hSpCas9	negative selection	4035585
74619294	74619317	15	+	26780180	HT29	viability (GeCKOv2 library)	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.77258041144998	[]	[]	3	hSpCas9	negative selection	4035586
74627374	74627397	15	-	26780180	HT29	viability (GeCKOv2 library)	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.503647863546318	[]	[]	1	hSpCas9	negative selection	4035587
74627428	74627451	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATACCTTGTGCTCATTGTAGAGG	CLK3	ENSG00000179335	-0.22771324908651228	[3]	[1,1]	-5	hSpCas9	positive selection	4128260
74619294	74619317	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.21671578243501927	[4]	[3,3]	5	hSpCas9	positive selection	4128261
74627428	74627451	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATACCTTGTGCTCATTGTAGAGG	CLK3	ENSG00000179335	0.6746575931254006	[4]	[3,2,2,3]	4	hSpCas9	positive selection	4192282
74619294	74619317	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.9234566867336601	[4]	[2,3,2,3]	6	hSpCas9	positive selection	4192283
74619294	74619317	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.9545822830726886	[2]	[2,6]	9	hSpCas9	positive selection	4263756
74627637	74627660	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.4366432249707097	[3]	[3,3]	8	hSpCas9	positive selection	4263757
74627624	74627647	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.28444736968773077	[3]	[2,0]	-5	hSpCas9	positive selection	4263758
74619234	74619257	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.518940845888997	[3]	[2,0]	-8	hSpCas9	positive selection	4328029
74627425	74627448	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.12041284043700873	[3]	[3,2]	2	hSpCas9	positive selection	4328030
74627374	74627397	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	-0.12755515708537668	[2]	[2,0]	-3	hSpCas9	positive selection	4328031
74619295	74619317	15	+	27760321	OCIAML3	viability	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.3417303635854836	[1055,913]	[964,984]	4	hSpCas9	negative selection	4390058
74619328	74619350	15	+	27760321	OCIAML3	viability	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.769615392661823	[384,290]	[278,665]	8	hSpCas9	negative selection	4390059
74620048	74620070	15	+	27760321	OCIAML3	viability	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.44748991437060703	[308,240]	[117,206]	-4	hSpCas9	negative selection	4390060
74620123	74620145	15	+	27760321	OCIAML3	viability	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.5193577339087927	[728,609]	[585,957]	6	hSpCas9	negative selection	4390061
74622188	74622210	15	-	27760321	OCIAML3	viability	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	0.28431083477270147	[551,529]	[417,643]	3	hSpCas9	negative selection	4390062
74619295	74619317	15	+	27760321	OCIAML2	viability	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.06691002190995565	[1055,913]	[737,785]	-1	hSpCas9	negative selection	4473521
74619328	74619350	15	+	27760321	OCIAML2	viability	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.16030219042722613	[384,290]	[249,372]	2	hSpCas9	negative selection	4473522
74620048	74620070	15	+	27760321	OCIAML2	viability	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.5270586007497284	[308,240]	[126,187]	-5	hSpCas9	negative selection	4473523
74620123	74620145	15	+	27760321	OCIAML2	viability	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.1273449238510016	[728,609]	[558,628]	1	hSpCas9	negative selection	4473524
74622188	74622210	15	-	27760321	OCIAML2	viability	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	0.03932546054159969	[551,529]	[402,512]	0	hSpCas9	negative selection	4473525
74619295	74619317	15	+	27760321	MV411	viability	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.07778357652172385	[1055,913]	[208,1222]	0	hSpCas9	negative selection	4556984
74619328	74619350	15	+	27760321	MV411	viability	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	-0.08874193640005568	[384,290]	[249,144]	0	hSpCas9	negative selection	4556985
74620048	74620070	15	+	27760321	MV411	viability	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.21663629567925713	[308,240]	[31,339]	-1	hSpCas9	negative selection	4556986
74620123	74620145	15	+	27760321	MV411	viability	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.4969170578383473	[728,609]	[584,674]	3	hSpCas9	negative selection	4556987
74622188	74622210	15	-	27760321	MV411	viability	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.5311057145028218	[551,529]	[314,145]	-4	hSpCas9	negative selection	4556988
74619295	74619317	15	+	27760321	HL60	viability	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.6747809876761637	[1055,913]	[1432,1119]	7	hSpCas9	negative selection	4640447
74619328	74619350	15	+	27760321	HL60	viability	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.7692096294911165	[384,290]	[474,457]	8	hSpCas9	negative selection	4640448
74620048	74620070	15	+	27760321	HL60	viability	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	0.04465721555554347	[308,240]	[266,190]	0	hSpCas9	negative selection	4640449
74620123	74620145	15	+	27760321	HL60	viability	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.499052129022884	[728,609]	[647,898]	6	hSpCas9	negative selection	4640450
74622188	74622210	15	-	27760321	HL60	viability	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	0.6402906735274138	[551,529]	[703,674]	7	hSpCas9	negative selection	4640451
74619295	74619317	15	+	27760321	HT1080	viability	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.2615870502938933	[913,712]	[461,307]	1	hSpCas9	negative selection	4723910
74619328	74619350	15	+	27760321	HT1080	viability	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	1.1963357899446696	[290,226]	[371,87]	6	hSpCas9	negative selection	4723911
74620048	74620070	15	+	27760321	HT1080	viability	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	0.6444567653575115	[240,187]	[134,131]	3	hSpCas9	negative selection	4723912
74620123	74620145	15	+	27760321	HT1080	viability	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.7008840742096203	[609,475]	[332,371]	4	hSpCas9	negative selection	4723913
74622188	74622210	15	-	27760321	HT1080	viability	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.04272292908712394	[529,413]	[267,88]	0	hSpCas9	negative selection	4723914
74619295	74619317	15	+	27760321	HT29	viability after 7 days	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.4378599924103106	[913,712]	[1711,1309,1272]	6	hSpCas9	negative selection	4807373
74619328	74619350	15	+	27760321	HT29	viability after 7 days	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.6307998730489828	[290,226]	[499,532,510]	8	hSpCas9	negative selection	4807374
74620048	74620070	15	+	27760321	HT29	viability after 7 days	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.7184595136762353	[240,187]	[154,121,221]	-7	hSpCas9	negative selection	4807375
74620123	74620145	15	+	27760321	HT29	viability after 7 days	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.0034795092240185177	[609,475]	[692,784,621]	0	hSpCas9	negative selection	4807376
74622188	74622210	15	-	27760321	HT29	viability after 7 days	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.266639566227013	[529,413]	[523,407,580]	-4	hSpCas9	negative selection	4807377
74619295	74619317	15	+	27760321	HT29	viability after 25 days	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.3062161345172827	[913,712]	[711,1304,1492]	3	hSpCas9	negative selection	4890836
74619328	74619350	15	+	27760321	HT29	viability after 25 days	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.9777400133209704	[290,226]	[655,419,676]	9	hSpCas9	negative selection	4890837
74620048	74620070	15	+	27760321	HT29	viability after 25 days	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.5090840789002182	[240,187]	[64,218,246]	-5	hSpCas9	negative selection	4890838
74620123	74620145	15	+	27760321	HT29	viability after 25 days	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.5425493625095441	[609,475]	[973,937,780]	6	hSpCas9	negative selection	4890839
74622188	74622210	15	-	27760321	HT29	viability after 25 days	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.045169591750685245	[529,413]	[387,588,607]	0	hSpCas9	negative selection	4890840
74619295	74619317	15	+	27760321	HT29	viability after 22 days	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.38179692919905706	[913,712]	[1220,1235,1218]	4	hSpCas9	negative selection	4974299
74619328	74619350	15	+	27760321	HT29	viability after 22 days	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.783292432365364	[290,226]	[301,486,764]	8	hSpCas9	negative selection	4974300
74620048	74620070	15	+	27760321	HT29	viability after 22 days	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	0.07273214091327396	[240,187]	[321,165,292]	0	hSpCas9	negative selection	4974301
74620123	74620145	15	+	27760321	HT29	viability after 22 days	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.5858733225494781	[609,475]	[763,1264,800]	6	hSpCas9	negative selection	4974302
74622188	74622210	15	-	27760321	HT29	viability after 22 days	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.3886932648634809	[529,413]	[307,354,591]	-4	hSpCas9	negative selection	4974303
74619295	74619317	15	+	27760321	HT29	viability after 19 days	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.6844061716459657	[913,712]	[1335,1832,1305]	7	hSpCas9	negative selection	5057762
74619328	74619350	15	+	27760321	HT29	viability after 19 days	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.9510197607489566	[290,226]	[582,707,432]	8	hSpCas9	negative selection	5057763
74620048	74620070	15	+	27760321	HT29	viability after 19 days	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.04359905301987199	[240,187]	[133,277,288]	0	hSpCas9	negative selection	5057764
74620123	74620145	15	+	27760321	HT29	viability after 19 days	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.4559544679497298	[609,475]	[1366,822,434]	4	hSpCas9	negative selection	5057765
74622188	74622210	15	-	27760321	HT29	viability after 19 days	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	0.39675459796279927	[529,413]	[729,512,883]	4	hSpCas9	negative selection	5057766
74619295	74619317	15	+	27760321	HT29	viability after 16 days	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.3631459532000547	[913,712]	[1270,946,1308]	4	hSpCas9	negative selection	5141225
74619328	74619350	15	+	27760321	HT29	viability after 16 days	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.4271249363622981	[290,226]	[615,355,218]	5	hSpCas9	negative selection	5141226
74620048	74620070	15	+	27760321	HT29	viability after 16 days	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.09531067335336996	[240,187]	[179,172,317]	-1	hSpCas9	negative selection	5141227
74620123	74620145	15	+	27760321	HT29	viability after 16 days	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.4850840811676349	[609,475]	[710,1141,676]	5	hSpCas9	negative selection	5141228
74622188	74622210	15	-	27760321	HT29	viability after 16 days	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.09300027915143094	[529,413]	[423,479,574]	-1	hSpCas9	negative selection	5141229
74619295	74619317	15	+	27760321	HT29	viability after 13 days	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.44827001387964716	[913,712]	[1402,1472,1003]	6	hSpCas9	negative selection	5224688
74619328	74619350	15	+	27760321	HT29	viability after 13 days	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.5556437914030634	[290,226]	[337,527,457]	7	hSpCas9	negative selection	5224689
74620048	74620070	15	+	27760321	HT29	viability after 13 days	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.4239479072291119	[240,187]	[230,185,141]	-5	hSpCas9	negative selection	5224690
74620123	74620145	15	+	27760321	HT29	viability after 13 days	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.5017086215503461	[609,475]	[856,1051,773]	6	hSpCas9	negative selection	5224691
74622188	74622210	15	-	27760321	HT29	viability after 13 days	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	0.11562740277390199	[529,413]	[575,715,493]	1	hSpCas9	negative selection	5224692
74619295	74619317	15	+	27760321	HT29	viability after 10 days	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.41870469574329916	[913,712]	[1366,1517,1195]	5	hSpCas9	negative selection	5308151
74619328	74619350	15	+	27760321	HT29	viability after 10 days	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.5312480708910742	[290,226]	[549,612,247]	7	hSpCas9	negative selection	5308152
74620048	74620070	15	+	27760321	HT29	viability after 10 days	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	-0.38878451963516314	[240,187]	[116,351,149]	-5	hSpCas9	negative selection	5308153
74620123	74620145	15	+	27760321	HT29	viability after 10 days	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.4891340052298496	[609,475]	[764,942,1141]	6	hSpCas9	negative selection	5308154
74622188	74622210	15	-	27760321	HT29	viability after 10 days	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.022630931610504945	[529,413]	[541,788,418]	0	hSpCas9	negative selection	5308155
74619295	74619317	15	+	27760321	MOLM13	viability	ACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.7180855749904032	[1055,913]	[330,341]	-4	hSpCas9	negative selection	5391614
74619328	74619350	15	+	27760321	MOLM13	viability	ACGAAGATCTCGGTCCAGAAGG	CLK3	ENSG00000179335	0.05404576829084656	[384,290]	[372,45]	0	hSpCas9	negative selection	5391615
74620048	74620070	15	+	27760321	MOLM13	viability	CCGTGACAGCGATACATACCGG	CLK3	ENSG00000179335	0.5745593051943755	[308,240]	[54,377]	4	hSpCas9	negative selection	5391616
74620123	74620145	15	+	27760321	MOLM13	viability	TCGTCATCGTCGGCGATCGCGG	CLK3	ENSG00000179335	0.45167170478538554	[728,609]	[520,508]	3	hSpCas9	negative selection	5391617
74622188	74622210	15	-	27760321	MOLM13	viability	TTGGAGCCAATCGCCGATCCGG	CLK3	ENSG00000179335	-0.7484101292285323	[551,529]	[235,135]	-4	hSpCas9	negative selection	5391618
74615846	74615869	15	+	27661255	K562	viability	GAGGCGCTCGGAGCGGGGAGTGG	CLK3	ENSG00000179335	-0.7496093811517238	[826,862]	[459,350]	-8	dCas9-KRAB	negative selection	5471501
74615887	74615910	15	+	27661255	K562	viability	GCCTGGGAGACGGTAAGTGTGGG	CLK3	ENSG00000179335	0.15716196538238988	[802,896]	[841,681]	5	dCas9-KRAB	negative selection	5471502
74598504	74598527	15	-	27661255	K562	viability	GGCAGAGGCGCAGCCTGTAGTGG	CLK3	ENSG00000179335	0.23063436915809332	[1111,1352]	[1196,1111]	7	dCas9-KRAB	negative selection	5471503
74598519	74598542	15	-	27661255	K562	viability	GGTGCCCCTCGCAGGGGCAGAGG	CLK3	ENSG00000179335	-0.11601289922974245	[439,462]	[352,314]	-4	dCas9-KRAB	negative selection	5471504
74615978	74616001	15	-	27661255	K562	viability	GGGAGTAGGCCGAGACCGAATGG	CLK3	ENSG00000179335	-0.045346237318990124	[1115,1300]	[1028,850]	-2	dCas9-KRAB	negative selection	5471505
74616019	74616042	15	-	27661255	K562	viability	GAGAGGTCGCGGCCCGATATGGG	CLK3	ENSG00000179335	0.1992708054656016	[1338,1587]	[1451,1240]	7	dCas9-KRAB	negative selection	5471506
74616298	74616321	15	-	27661255	K562	viability	GACAGAGGGAAAGCCGGACTGGG	CLK3	ENSG00000179335	-0.06924422789876675	[782,883]	[697,577]	-3	dCas9-KRAB	negative selection	5471507
74619294	74619317	15	+	27260156	BXPC3	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.19695537539123698	[449]	[419,513,556,696]	4	hSpCas9	negative selection	5536216
74627637	74627660	15	+	27260156	BXPC3	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.36941397882335936	[522]	[730,581,635,898]	7	hSpCas9	negative selection	5536217
74627624	74627647	15	-	27260156	BXPC3	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.22808567189048382	[478]	[529,484,628,728]	5	hSpCas9	negative selection	5536218
74619234	74619257	15	+	27260156	BXPC3	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.3631955521786478	[795]	[695,639,574,668]	-7	hSpCas9	negative selection	5600489
74627425	74627448	15	+	27260156	BXPC3	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.13857075705125366	[665]	[744,637,821,880]	3	hSpCas9	negative selection	5600490
74627374	74627397	15	-	27260156	BXPC3	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.5138335793025629	[266]	[323,429,476,363]	9	hSpCas9	negative selection	5600491
74619294	74619317	15	+	27260156	A673	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.23031300310688024	[449]	[663,511,699,665]	5	hSpCas9	negative selection	5657467
74627637	74627660	15	+	27260156	A673	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.5038736270875601	[522]	[1048,773,936,816]	9	hSpCas9	negative selection	5657468
74627624	74627647	15	-	27260156	A673	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.2574022228836722	[478]	[725,427,678,940]	6	hSpCas9	negative selection	5657469
74619234	74619257	15	+	27260156	A673	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.3550337438498986	[795]	[783,781,744,675]	-7	hSpCas9	negative selection	5721740
74627425	74627448	15	+	27260156	A673	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.15302844545595928	[665]	[1007,775,890,896]	3	hSpCas9	negative selection	5721741
74627374	74627397	15	-	27260156	A673	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.49687351307558664	[266]	[541,407,425,443]	9	hSpCas9	negative selection	5721742
74619294	74619317	15	+	27260156	A375	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.33065472066819135	[449]	[367,370,577,353]	-5	hSpCas9	negative selection	5778718
74627637	74627660	15	+	27260156	A375	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.0921773722630378	[522]	[789,587,829,414]	1	hSpCas9	negative selection	5778719
74627624	74627647	15	-	27260156	A375	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.02233651298747589	[478]	[567,500,615,513]	0	hSpCas9	negative selection	5778720
74619234	74619257	15	+	27260156	A375	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5434810517952795	[795]	[718,689,750,422]	-6	hSpCas9	negative selection	5842991
74627425	74627448	15	+	27260156	A375	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.09261926499316275	[665]	[664,1069,746,860]	1	hSpCas9	negative selection	5842992
74627374	74627397	15	-	27260156	A375	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.5629864961917277	[266]	[501,588,425,354]	8	hSpCas9	negative selection	5842993
74619294	74619317	15	+	27260156	COLO741	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.03393152066339787	[449]	[657,603,438]	0	hSpCas9	negative selection	5899969
74627637	74627660	15	+	27260156	COLO741	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.4700124403317606	[522]	[1216,853,741]	8	hSpCas9	negative selection	5899970
74627624	74627647	15	-	27260156	COLO741	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.1774987624228561	[478]	[728,578,344]	-4	hSpCas9	negative selection	5899971
74619234	74619257	15	+	27260156	COLO741	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.6696560223978397	[795]	[572,681,654]	-8	hSpCas9	negative selection	5964242
74627425	74627448	15	+	27260156	COLO741	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.08830660686304814	[665]	[1179,806,758]	2	hSpCas9	negative selection	5964243
74627374	74627397	15	-	27260156	COLO741	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.3590050268022947	[266]	[515,362,438]	7	hSpCas9	negative selection	5964244
74619294	74619317	15	+	27260156	CAL120	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.1890423584491573	[449]	[567,483,433]	-3	hSpCas9	negative selection	6021220
74627637	74627660	15	+	27260156	CAL120	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.2748113905603182	[522]	[935,818,631]	4	hSpCas9	negative selection	6021221
74627624	74627647	15	-	27260156	CAL120	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.04373472333241349	[478]	[939,395,556]	0	hSpCas9	negative selection	6021222
74619234	74619257	15	+	27260156	CAL120	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.4685676225800752	[795]	[830,642,690]	-6	hSpCas9	negative selection	6085493
74627425	74627448	15	+	27260156	CAL120	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.08524676198716785	[665]	[767,887,962]	1	hSpCas9	negative selection	6085494
74627374	74627397	15	-	27260156	CAL120	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.4622235796484323	[266]	[548,338,497]	7	hSpCas9	negative selection	6085495
74619294	74619317	15	+	27260156	CADOES1	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.6592386829869014	[449]	[288,336,249,180]	-8	hSpCas9	negative selection	6142471
74627637	74627660	15	+	27260156	CADOES1	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	-0.05736525923618595	[522]	[421,483,444,520]	-1	hSpCas9	negative selection	6142472
74627624	74627647	15	-	27260156	CADOES1	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.02186238106981978	[478]	[568,495,317,424]	0	hSpCas9	negative selection	6142473
74619234	74619257	15	+	27260156	CADOES1	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.8118617372588857	[795]	[511,415,455,297]	-8	hSpCas9	negative selection	6206744
74627425	74627448	15	+	27260156	CADOES1	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.1313101303402146	[665]	[581,563,628,483]	-2	hSpCas9	negative selection	6206745
74627374	74627397	15	-	27260156	CADOES1	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.7421070049176304	[266]	[448,504,305,400]	9	hSpCas9	negative selection	6206746
74619294	74619317	15	+	27260156	EWS502	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.04930927864036096	[449]	[507,409,456,604]	0	hSpCas9	negative selection	6263722
74627637	74627660	15	+	27260156	EWS502	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.32989392812889173	[522]	[639,644,793,714]	6	hSpCas9	negative selection	6263723
74627624	74627647	15	-	27260156	EWS502	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.12205590410887869	[478]	[606,477,532,586]	2	hSpCas9	negative selection	6263724
74619234	74619257	15	+	27260156	EWS502	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5039144986548965	[795]	[566,529,662,624]	-7	hSpCas9	negative selection	6327995
74627425	74627448	15	+	27260156	EWS502	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.1513735878544662	[665]	[590,821,941,800]	2	hSpCas9	negative selection	6327996
74627374	74627397	15	-	27260156	EWS502	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.48019716924131023	[266]	[469,396,350,344]	8	hSpCas9	negative selection	6327997
74619294	74619317	15	+	27260156	EW8	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.19782228303905403	[449]	[356,364,249,314]	-4	hSpCas9	negative selection	6384973
74627637	74627660	15	+	27260156	EW8	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	-0.11636170631879622	[522]	[536,344,396,298]	-2	hSpCas9	negative selection	6384974
74627624	74627647	15	-	27260156	EW8	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.45182879636932205	[478]	[332,248,233,331]	-7	hSpCas9	negative selection	6384975
74619234	74619257	15	+	27260156	EW8	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.6226909605272823	[795]	[642,323,347,395]	-8	hSpCas9	negative selection	6449246
74627425	74627448	15	+	27260156	EW8	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.05554274759692579	[665]	[480,460,435,706]	-1	hSpCas9	negative selection	6449247
74627374	74627397	15	-	27260156	EW8	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.32940652296322676	[266]	[219,225,328,295]	6	hSpCas9	negative selection	6449248
74619294	74619317	15	+	27260156	CORL105	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.27771218580135015	[449]	[577,567,606,794]	5	hSpCas9	negative selection	6506224
74627637	74627660	15	+	27260156	CORL105	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.17591134083491786	[522]	[799,558,718,698]	3	hSpCas9	negative selection	6506225
74627624	74627647	15	-	27260156	CORL105	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.28763258193294217	[478]	[750,515,997,527]	5	hSpCas9	negative selection	6506226
74619234	74619257	15	+	27260156	CORL105	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.6136875395997478	[795]	[573,702,752,425]	-8	hSpCas9	negative selection	6570497
74627425	74627448	15	+	27260156	CORL105	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.0758463204606507	[665]	[703,843,753,655]	-1	hSpCas9	negative selection	6570498
74627374	74627397	15	-	27260156	CORL105	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.5125306283160567	[266]	[338,511,568,377]	8	hSpCas9	negative selection	6570499
74619294	74619317	15	+	27260156	HS294T	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.1366149105790761	[449]	[139,149,173,329]	1	hSpCas9	negative selection	6627475
74627637	74627660	15	+	27260156	HS294T	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.8833760944951389	[522]	[455,254,416,355]	9	hSpCas9	negative selection	6627476
74627624	74627647	15	-	27260156	HS294T	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.21885792475693494	[478]	[191,195,267,206]	3	hSpCas9	negative selection	6627477
74619234	74619257	15	+	27260156	HS294T	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5360394186083932	[795]	[209,134,204,318]	-6	hSpCas9	negative selection	6691748
74627425	74627448	15	+	27260156	HS294T	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.4315580271530054	[665]	[479,241,217,456]	6	hSpCas9	negative selection	6691749
74627374	74627397	15	-	27260156	HS294T	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.36000362422730253	[266]	[70,251,97,105]	5	hSpCas9	negative selection	6691750
74619294	74619317	15	+	27260156	HCC44	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.030391623070097913	[449]	[612,498,627,369]	0	hSpCas9	negative selection	6748726
74627637	74627660	15	+	27260156	HCC44	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	-0.27946064878706456	[522]	[357,274,836,551]	-4	hSpCas9	negative selection	6748727
74627624	74627647	15	-	27260156	HCC44	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.2611403179972421	[478]	[639,382,408,393]	-4	hSpCas9	negative selection	6748728
74619234	74619257	15	+	27260156	HCC44	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5435530052675867	[795]	[657,426,899,561]	-7	hSpCas9	negative selection	6812999
74627425	74627448	15	+	27260156	HCC44	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.002993447731009513	[665]	[852,664,716,791]	0	hSpCas9	negative selection	6813000
74627374	74627397	15	-	27260156	HCC44	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.6919040604520641	[266]	[669,373,545,402]	9	hSpCas9	negative selection	6813001
74619294	74619317	15	+	27260156	G402	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.2148586181296866	[449]	[386,309,704,466]	-3	hSpCas9	negative selection	6869977
74627637	74627660	15	+	27260156	G402	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.13712152290094734	[522]	[943,917,478,519]	1	hSpCas9	negative selection	6869978
74627624	74627647	15	-	27260156	G402	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.2738883445436056	[478]	[818,433,423,308]	-3	hSpCas9	negative selection	6869979
74619234	74619257	15	+	27260156	G402	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.31423957368245137	[795]	[827,571,780,927]	-4	hSpCas9	negative selection	6934250
74627425	74627448	15	+	27260156	G402	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.31152786524707865	[665]	[1012,1079,1018,926]	4	hSpCas9	negative selection	6934251
74627374	74627397	15	-	27260156	G402	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	1.086411380333948	[266]	[1092,714,242,768]	9	hSpCas9	negative selection	6934252
74619294	74619317	15	+	27260156	L33	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.3246554547149666	[449]	[499,232,387,569]	7	hSpCas9	negative selection	6991228
74627637	74627660	15	+	27260156	L33	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.4090348816048952	[522]	[608,251,508,745]	8	hSpCas9	negative selection	6991229
74627624	74627647	15	-	27260156	L33	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.15866414805906992	[478]	[659,206,331,442]	3	hSpCas9	negative selection	6991230
74619234	74619257	15	+	27260156	L33	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5614094139094139	[795]	[522,243,323,523]	-8	hSpCas9	negative selection	7055501
74627425	74627448	15	+	27260156	L33	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.08783277650647986	[665]	[529,268,407,672]	-2	hSpCas9	negative selection	7055502
74627374	74627397	15	-	27260156	L33	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.2494184249484126	[266]	[254,137,216,333]	5	hSpCas9	negative selection	7055503
74619294	74619317	15	+	27260156	K562	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.008451138230202854	[449]	[584,606,151,298]	0	hSpCas9	negative selection	7112479
74627637	74627660	15	+	27260156	K562	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.5816772878911757	[522]	[827,784,689,509]	7	hSpCas9	negative selection	7112480
74627624	74627647	15	-	27260156	K562	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.4785966807429743	[478]	[578,489,564,711]	6	hSpCas9	negative selection	7112481
74619234	74619257	15	+	27260156	K562	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.6062489747876383	[795]	[739,437,427,289]	-6	hSpCas9	negative selection	7176752
74627425	74627448	15	+	27260156	K562	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.22232539121881423	[665]	[653,921,504,683]	2	hSpCas9	negative selection	7176753
74627374	74627397	15	-	27260156	K562	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.24667329731819376	[266]	[289,269,230,326]	3	hSpCas9	negative selection	7176754
74619294	74619317	15	+	27260156	HT29	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.0021519611966403923	[449]	[492,669,521,512]	0	hSpCas9	negative selection	7233730
74627637	74627660	15	+	27260156	HT29	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.19112870053344463	[522]	[838,952,639,519]	4	hSpCas9	negative selection	7233731
74627624	74627647	15	-	27260156	HT29	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.341294875259155	[478]	[438,344,582,456]	-6	hSpCas9	negative selection	7233732
74619234	74619257	15	+	27260156	HT29	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.42332007297864005	[795]	[699,853,590,742]	-7	hSpCas9	negative selection	7298003
74627425	74627448	15	+	27260156	HT29	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.130837703305825	[665]	[918,838,1029,764]	2	hSpCas9	negative selection	7298004
74627374	74627397	15	-	27260156	HT29	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.6227957527983546	[266]	[532,447,605,416]	9	hSpCas9	negative selection	7298005
74619294	74619317	15	+	27260156	MHHES1	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.027546805197556715	[449]	[506,695,512,323]	0	hSpCas9	negative selection	7354981
74627637	74627660	15	+	27260156	MHHES1	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.4261853201661645	[522]	[821,797,914,650]	7	hSpCas9	negative selection	7354982
74627624	74627647	15	-	27260156	MHHES1	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.17269797279353022	[478]	[813,739,659,312]	3	hSpCas9	negative selection	7354983
74619234	74619257	15	+	27260156	MHHES1	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.4857173596847771	[795]	[503,895,561,601]	-7	hSpCas9	negative selection	7419254
74627425	74627448	15	+	27260156	MHHES1	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.09287824065979633	[665]	[1127,565,851,679]	1	hSpCas9	negative selection	7419255
74627374	74627397	15	-	27260156	MHHES1	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.7991413138541429	[266]	[624,441,748,318]	9	hSpCas9	negative selection	7419256
74619294	74619317	15	+	27260156	MEWO	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.14984129344408437	[449]	[431,536,424]	3	hSpCas9	negative selection	7476232
74627637	74627660	15	+	27260156	MEWO	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.07375156488643403	[522]	[496,574,468]	1	hSpCas9	negative selection	7476233
74627624	74627647	15	-	27260156	MEWO	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.3887956116412628	[478]	[274,280,457]	-7	hSpCas9	negative selection	7476234
74619234	74619257	15	+	27260156	MEWO	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.6870343639462512	[795]	[589,311,510]	-8	hSpCas9	negative selection	7540505
74627425	74627448	15	+	27260156	MEWO	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.032341689497728754	[665]	[833,557,557]	0	hSpCas9	negative selection	7540506
74627374	74627397	15	-	27260156	MEWO	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.09786592930772986	[266]	[452,245,138]	2	hSpCas9	negative selection	7540507
74619294	74619317	15	+	27260156	LNCAPCLONEFGC	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.13777355902967492	[449]	[435,296,394,360]	-2	hSpCas9	negative selection	7597483
74627637	74627660	15	+	27260156	LNCAPCLONEFGC	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	-0.08978716059003997	[522]	[328,408,646,429]	-1	hSpCas9	negative selection	7597484
74627624	74627647	15	-	27260156	LNCAPCLONEFGC	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.09356371830679182	[478]	[324,522,561,454]	1	hSpCas9	negative selection	7597485
74619234	74619257	15	+	27260156	LNCAPCLONEFGC	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.6583310967075339	[795]	[508,418,539,372]	-7	hSpCas9	negative selection	7661756
74627425	74627448	15	+	27260156	LNCAPCLONEFGC	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.25349443990030374	[665]	[781,554,793,765]	4	hSpCas9	negative selection	7661757
74627374	74627397	15	-	27260156	LNCAPCLONEFGC	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.5340197492886174	[266]	[234,224,618,371]	8	hSpCas9	negative selection	7661758
74619294	74619317	15	+	27260156	PANC0327	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.6063840014085069	[449]	[868,393,532,686]	8	hSpCas9	negative selection	7718734
74627637	74627660	15	+	27260156	PANC0327	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.5610001428872292	[522]	[912,636,515,699]	7	hSpCas9	negative selection	7718735
74627624	74627647	15	-	27260156	PANC0327	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.6773451644718185	[478]	[629,1138,425,462]	8	hSpCas9	negative selection	7718736
74619234	74619257	15	+	27260156	PANC0327	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.09532999005991771	[795]	[1032,456,545,667]	-1	hSpCas9	negative selection	7783007
74627425	74627448	15	+	27260156	PANC0327	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.7382008051822303	[665]	[1022,846,942,1154]	9	hSpCas9	negative selection	7783008
74627374	74627397	15	-	27260156	PANC0327	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	1.4062376906904532	[266]	[401,1135,421,469]	9	hSpCas9	negative selection	7783009
74619294	74619317	15	+	27260156	NCIH2009	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.25979316244694844	[449]	[1040,642,631]	3	hSpCas9	negative selection	7839985
74627637	74627660	15	+	27260156	NCIH2009	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.1709399634561297	[522]	[791,901,764]	2	hSpCas9	negative selection	7839986
74627624	74627647	15	-	27260156	NCIH2009	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.5725209688749312	[478]	[1335,1015,698]	7	hSpCas9	negative selection	7839987
74619234	74619257	15	+	27260156	NCIH2009	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.3119371576852386	[795]	[913,715,1062]	-4	hSpCas9	negative selection	7904258
74627425	74627448	15	+	27260156	NCIH2009	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.0326446766982561	[665]	[1264,934,715]	0	hSpCas9	negative selection	7904259
74627374	74627397	15	-	27260156	NCIH2009	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.2519420586178349	[266]	[565,442,346]	3	hSpCas9	negative selection	7904260
74619294	74619317	15	+	27260156	NCIH1373	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.3738327702669172	[449]	[432,496,325,75]	-4	hSpCas9	negative selection	7961236
74627637	74627660	15	+	27260156	NCIH1373	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.5820798450610198	[522]	[1147,820,656,245]	6	hSpCas9	negative selection	7961237
74627624	74627647	15	-	27260156	NCIH1373	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.3980527851726836	[478]	[955,591,500,220]	4	hSpCas9	negative selection	7961238
74619234	74619257	15	+	27260156	NCIH1373	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5524906050166486	[795]	[1117,426,348,168]	-5	hSpCas9	negative selection	8025509
74627425	74627448	15	+	27260156	NCIH1373	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.3503180368505363	[665]	[1056,852,1036,229]	3	hSpCas9	negative selection	8025510
74627374	74627397	15	-	27260156	NCIH1373	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	1.4084895988351303	[266]	[452,1071,1063,124]	9	hSpCas9	negative selection	8025511
74619294	74619317	15	+	27260156	PATU8902	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-1.2215927867251704	[449]	[192,579,128,200]	-8	hSpCas9	negative selection	8082487
74627637	74627660	15	+	27260156	PATU8902	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.06871960804600635	[522]	[609,1234,581,660]	0	hSpCas9	negative selection	8082488
74627624	74627647	15	-	27260156	PATU8902	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.4113183517086445	[478]	[500,522,385,638]	-4	hSpCas9	negative selection	8082489
74619234	74619257	15	+	27260156	PATU8902	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.730553932914195	[795]	[740,1129,387,455]	-6	hSpCas9	negative selection	8146760
74627425	74627448	15	+	27260156	PATU8902	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.783467931217218	[665]	[448,653,308,835]	-6	hSpCas9	negative selection	8146761
74627374	74627397	15	-	27260156	PATU8902	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.1263880459575294	[266]	[531,324,267,545]	1	hSpCas9	negative selection	8146762
74619294	74619317	15	+	27260156	PANC1	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.06016301252999274	[449]	[418,483,336,383]	0	hSpCas9	negative selection	8203738
74627637	74627660	15	+	27260156	PANC1	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.029671907501755912	[522]	[465,507,515,362]	0	hSpCas9	negative selection	8203739
74627624	74627647	15	-	27260156	PANC1	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.10371670469875795	[478]	[339,912,323,304]	1	hSpCas9	negative selection	8203740
74619234	74619257	15	+	27260156	PANC1	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5617019679237989	[795]	[648,445,496,276]	-7	hSpCas9	negative selection	8268011
74627425	74627448	15	+	27260156	PANC1	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.14104364704851025	[665]	[666,847,484,565]	2	hSpCas9	negative selection	8268012
74627374	74627397	15	-	27260156	PANC1	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.8503039601894596	[266]	[295,629,522,269]	9	hSpCas9	negative selection	8268013
74619294	74619317	15	+	27260156	PANC0813	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.3742036759182499	[449]	[832,633,709,581]	6	hSpCas9	negative selection	8324989
74627637	74627660	15	+	27260156	PANC0813	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.35936768709564326	[522]	[1057,793,725,607]	6	hSpCas9	negative selection	8324990
74627624	74627647	15	-	27260156	PANC0813	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.2579513433362048	[478]	[686,681,729,596]	4	hSpCas9	negative selection	8324991
74619234	74619257	15	+	27260156	PANC0813	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.2552944124999351	[795]	[737,734,915,741]	-4	hSpCas9	negative selection	8389262
74627425	74627448	15	+	27260156	PANC0813	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.32228829071740484	[665]	[899,808,1132,1057]	5	hSpCas9	negative selection	8389263
74627374	74627397	15	-	27260156	PANC0813	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.23960943523078937	[266]	[553,412,287,248]	4	hSpCas9	negative selection	8389264
74619294	74619317	15	+	27260156	RDES	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.2854773612630605	[449]	[307,369,529,528]	-5	hSpCas9	negative selection	8446240
74627637	74627660	15	+	27260156	RDES	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.2633753066839096	[522]	[536,897,699,757]	4	hSpCas9	negative selection	8446241
74627624	74627647	15	-	27260156	RDES	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.03800708585742649	[478]	[513,582,575,582]	0	hSpCas9	negative selection	8446242
74619234	74619257	15	+	27260156	RDES	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.6717860402214815	[795]	[505,637,466,690]	-8	hSpCas9	negative selection	8510513
74627425	74627448	15	+	27260156	RDES	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.13035701518513887	[665]	[743,842,910,852]	2	hSpCas9	negative selection	8510514
74627374	74627397	15	-	27260156	RDES	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.6733307957354244	[266]	[462,417,478,613]	9	hSpCas9	negative selection	8510515
74619294	74619317	15	+	27260156	PC3	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.052486606495717014	[449]	[280,339,663,569]	-1	hSpCas9	negative selection	8567491
74627637	74627660	15	+	27260156	PC3	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	-0.006195675156176028	[522]	[344,257,960,733]	0	hSpCas9	negative selection	8567492
74627624	74627647	15	-	27260156	PC3	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.362366994609861	[478]	[242,352,611,391]	-7	hSpCas9	negative selection	8567493
74619234	74619257	15	+	27260156	PC3	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.7991345977886568	[795]	[260,398,779,562]	-9	hSpCas9	negative selection	8631764
74627425	74627448	15	+	27260156	PC3	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.10326188935391123	[665]	[522,672,1235,625]	2	hSpCas9	negative selection	8631765
74627374	74627397	15	-	27260156	PC3	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.005218807128515857	[266]	[139,364,322,289]	0	hSpCas9	negative selection	8631766
74619294	74619317	15	+	27260156	PATU8988T	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.3865974011614639	[449]	[761,483,476,541]	6	hSpCas9	negative selection	8688742
74627637	74627660	15	+	27260156	PATU8988T	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.49116320855267215	[522]	[494,840,640,891]	7	hSpCas9	negative selection	8688743
74627624	74627647	15	-	27260156	PATU8988T	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.05998527004880318	[478]	[469,848,358,270]	1	hSpCas9	negative selection	8688744
74619234	74619257	15	+	27260156	PATU8988T	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.2030490857812437	[795]	[607,821,512,752]	-3	hSpCas9	negative selection	8753015
74627425	74627448	15	+	27260156	PATU8988T	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.08105354683426852	[665]	[584,770,440,657]	-1	hSpCas9	negative selection	8753016
74627374	74627397	15	-	27260156	PATU8988T	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.8082995547966956	[266]	[495,449,541,305]	9	hSpCas9	negative selection	8753017
74619294	74619317	15	+	27260156	T47D	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.11787550673171972	[449]	[531,446,509,444]	-3	hSpCas9	negative selection	8809993
74627637	74627660	15	+	27260156	T47D	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	-0.15613845465883996	[522]	[575,461,618,535]	-3	hSpCas9	negative selection	8809994
74627624	74627647	15	-	27260156	T47D	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.03322717251694152	[478]	[541,613,559,563]	0	hSpCas9	negative selection	8809995
74619234	74619257	15	+	27260156	T47D	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5894046732375384	[795]	[657,667,524,610]	-8	hSpCas9	negative selection	8874266
74627425	74627448	15	+	27260156	T47D	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.07140572899040187	[665]	[765,751,873,874]	1	hSpCas9	negative selection	8874267
74627374	74627397	15	-	27260156	T47D	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.7185756278799579	[266]	[520,442,540,548]	9	hSpCas9	negative selection	8874268
74619294	74619317	15	+	27260156	SU8686	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.029310885786951298	[449]	[400,341,490,634]	0	hSpCas9	negative selection	8931244
74627637	74627660	15	+	27260156	SU8686	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.27277884931228824	[522]	[542,582,681,725]	4	hSpCas9	negative selection	8931245
74627624	74627647	15	-	27260156	SU8686	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.042650402504532225	[478]	[440,435,505,600]	0	hSpCas9	negative selection	8931246
74619234	74619257	15	+	27260156	SU8686	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.7676444577805682	[795]	[367,418,495,608]	-8	hSpCas9	negative selection	8995517
74627425	74627448	15	+	27260156	SU8686	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.02954356808155756	[665]	[622,591,658,732]	0	hSpCas9	negative selection	8995518
74627374	74627397	15	-	27260156	SU8686	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.3810102174393117	[266]	[324,274,485,297]	6	hSpCas9	negative selection	8995519
74619294	74619317	15	+	27260156	SKES1	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.29107044928591275	[449]	[270,380,399,395]	-6	hSpCas9	negative selection	9052495
74627637	74627660	15	+	27260156	SKES1	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.22456342821302686	[522]	[641,585,578,624]	5	hSpCas9	negative selection	9052496
74627624	74627647	15	-	27260156	SKES1	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	-0.13295823867270776	[478]	[514,497,428,327]	-3	hSpCas9	negative selection	9052497
74619234	74619257	15	+	27260156	SKES1	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.4930746566126656	[795]	[702,575,573,433]	-8	hSpCas9	negative selection	9116768
74627425	74627448	15	+	27260156	SKES1	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.05660465177854612	[665]	[662,837,717,565]	1	hSpCas9	negative selection	9116769
74627374	74627397	15	-	27260156	SKES1	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.49937892867731476	[266]	[300,389,419,380]	8	hSpCas9	negative selection	9116770
74619294	74619317	15	+	27260156	TOV112D	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	0.020393490828414435	[449]	[502,481,406,445]	0	hSpCas9	negative selection	9173746
74627637	74627660	15	+	27260156	TOV112D	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.23884366415056865	[522]	[456,933,539,604]	4	hSpCas9	negative selection	9173747
74627624	74627647	15	-	27260156	TOV112D	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.2985621945836935	[478]	[886,530,445,507]	5	hSpCas9	negative selection	9173748
74619234	74619257	15	+	27260156	TOV112D	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.5073192659996133	[795]	[331,638,618,649]	-7	hSpCas9	negative selection	9238019
74627425	74627448	15	+	27260156	TOV112D	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.011184843508359799	[665]	[258,1063,775,650]	0	hSpCas9	negative selection	9238020
74627374	74627397	15	-	27260156	TOV112D	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.2928844527615242	[266]	[277,640,214,250]	5	hSpCas9	negative selection	9238021
74619294	74619317	15	+	27260156	TC71	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.21163453890982697	[449]	[467,383,383,430]	-5	hSpCas9	negative selection	9294997
74627637	74627660	15	+	27260156	TC71	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.30649157927718584	[522]	[740,701,567,769]	7	hSpCas9	negative selection	9294998
74627624	74627647	15	-	27260156	TC71	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.19156742706188953	[478]	[632,596,591,517]	5	hSpCas9	negative selection	9294999
74619234	74619257	15	+	27260156	TC71	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.40238412904683374	[795]	[667,587,665,659]	-8	hSpCas9	negative selection	9359270
74627425	74627448	15	+	27260156	TC71	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	-0.04428855922058833	[665]	[645,793,619,713]	-1	hSpCas9	negative selection	9359271
74627374	74627397	15	-	27260156	TC71	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.7149285306867246	[266]	[602,421,442,404]	9	hSpCas9	negative selection	9359272
74619294	74619317	15	+	27260156	TC32	viability	GACTGCGATACCCGTCCCGAAGG	CLK3	ENSG00000179335	-0.33817995320468247	[449]	[327,278,392,349]	-6	hSpCas9	negative selection	9416248
74627637	74627660	15	+	27260156	TC32	viability	CCGTCACTATCGCCCGCCTGAGG	CLK3	ENSG00000179335	0.28632040179224527	[522]	[633,352,864,648]	5	hSpCas9	negative selection	9416249
74627624	74627647	15	-	27260156	TC32	viability	ATAGTGACGGGTGGCCACAATGG	CLK3	ENSG00000179335	0.1740110565313169	[478]	[510,365,637,564]	3	hSpCas9	negative selection	9416250
74619234	74619257	15	+	27260156	TC32	viability	ACCCGTACCTGAGCTACCGATGG	CLK3	ENSG00000179335	-0.691807459835316	[795]	[372,368,565,588]	-8	hSpCas9	negative selection	9480521
74627425	74627448	15	+	27260156	TC32	viability	AACCCTCTACAATGAGCACAAGG	CLK3	ENSG00000179335	0.07534664486172282	[665]	[543,532,870,754]	1	hSpCas9	negative selection	9480522
74627374	74627397	15	-	27260156	TC32	viability	TCTCTGGTTTCAAGTCTGTATGG	CLK3	ENSG00000179335	0.908238961159895	[266]	[296,469,591,542]	9	hSpCas9	negative selection	9480523
74615662	74615685	15	-	27869803	HPAFII	viability after 27 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-1.2952771273842127	[187]	[36,42,NaN]	-7	hSpCas9	negative selection	9554720
74619243	74619266	15	+	27869803	HPAFII	viability after 27 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.5498102555999034	[484]	[315,55,NaN]	-4	hSpCas9	negative selection	9554721
74620218	74620241	15	-	27869803	HPAFII	viability after 27 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-1.8217271823140289	[650]	[98,94,NaN]	-8	hSpCas9	negative selection	9554722
74622179	74622202	15	-	27869803	HPAFII	viability after 27 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.7053068271470166	[183]	[202,119,NaN]	6	hSpCas9	negative selection	9554723
74622513	74622536	15	+	27869803	HPAFII	viability after 27 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.4505510621597458	[206]	[29,120,NaN]	-3	hSpCas9	negative selection	9554724
74624920	74624943	15	+	27869803	HPAFII	viability after 27 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.8579182623686803	[1068]	[398,235,NaN]	-6	hSpCas9	negative selection	9554725
74615662	74615685	15	-	27869803	HPAFII	viability after 15 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-1.0165943888311189	[187]	[126,82,NaN]	-7	hSpCas9	negative selection	9637169
74619243	74619266	15	+	27869803	HPAFII	viability after 15 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.8053386141392243	[484]	[510,165,NaN]	-7	hSpCas9	negative selection	9637170
74620218	74620241	15	-	27869803	HPAFII	viability after 15 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-1.6025508521760286	[650]	[304,183,NaN]	-8	hSpCas9	negative selection	9637171
74622179	74622202	15	-	27869803	HPAFII	viability after 15 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.7820795844890225	[183]	[545,211,NaN]	8	hSpCas9	negative selection	9637172
74622513	74622536	15	+	27869803	HPAFII	viability after 15 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.1934942053387147	[206]	[151,220,NaN]	-2	hSpCas9	negative selection	9637173
74624920	74624943	15	+	27869803	HPAFII	viability after 15 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.9533285562788321	[1068]	[736,503,NaN]	-7	hSpCas9	negative selection	9637174
74615662	74615685	15	-	27869803	ASPC1	viability after 36 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	0.24362651877995845	[332]	[45,306,65]	2	hSpCas9	negative selection	9719618
74619243	74619266	15	+	27869803	ASPC1	viability after 36 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.06331917481440219	[921]	[491,215,318]	0	hSpCas9	negative selection	9719619
74620218	74620241	15	-	27869803	ASPC1	viability after 36 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.22255086236201438	[1363]	[258,371,536]	-2	hSpCas9	negative selection	9719620
74622179	74622202	15	-	27869803	ASPC1	viability after 36 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.7562865482020562	[426]	[109,152,426]	7	hSpCas9	negative selection	9719621
74622513	74622536	15	+	27869803	ASPC1	viability after 36 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.2714597210790284	[672]	[117,155,497]	2	hSpCas9	negative selection	9719622
74624920	74624943	15	+	27869803	ASPC1	viability after 36 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	0.539035251370688	[2610]	[1125,1004,1702]	5	hSpCas9	negative selection	9719623
74615662	74615685	15	-	27869803	PATU8988S	viability after 35 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-0.48917856491717115	[323]	[77,107,NaN]	-5	hSpCas9	negative selection	9802067
74619243	74619266	15	+	27869803	PATU8988S	viability after 35 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.5567533608416384	[793]	[172,261,NaN]	-5	hSpCas9	negative selection	9802068
74620218	74620241	15	-	27869803	PATU8988S	viability after 35 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-0.22810277729865291	[928]	[291,346,NaN]	-2	hSpCas9	negative selection	9802069
74622179	74622202	15	-	27869803	PATU8988S	viability after 35 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.15039252403103395	[436]	[124,265,NaN]	1	hSpCas9	negative selection	9802070
74622513	74622536	15	+	27869803	PATU8988S	viability after 35 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.361464719073692	[404]	[110,142,NaN]	-4	hSpCas9	negative selection	9802071
74624920	74624943	15	+	27869803	PATU8988S	viability after 35 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.3747226077444803	[1967]	[525,696,NaN]	-4	hSpCas9	negative selection	9802072
74615662	74615685	15	-	27869803	PATU8988S	viability after 31 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-0.38743380835429897	[323]	[129,58,NaN]	-4	hSpCas9	negative selection	9884516
74619243	74619266	15	+	27869803	PATU8988S	viability after 31 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.2820479008656541	[793]	[167,377,NaN]	-3	hSpCas9	negative selection	9884517
74620218	74620241	15	-	27869803	PATU8988S	viability after 31 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	0.015304368890731057	[928]	[292,477,NaN]	0	hSpCas9	negative selection	9884518
74622179	74622202	15	-	27869803	PATU8988S	viability after 31 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	-0.7458413463438585	[436]	[51,169,NaN]	-7	hSpCas9	negative selection	9884519
74622513	74622536	15	+	27869803	PATU8988S	viability after 31 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.22564901375737906	[404]	[83,206,NaN]	-3	hSpCas9	negative selection	9884520
74624920	74624943	15	+	27869803	PATU8988S	viability after 31 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.2563724453936558	[1967]	[491,866,NaN]	-3	hSpCas9	negative selection	9884521
74615662	74615685	15	-	27869803	HPAFII	viability after 35 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-1.3882325507450468	[187]	[49,20,NaN]	-6	hSpCas9	negative selection	9966965
74619243	74619266	15	+	27869803	HPAFII	viability after 35 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.6566182665153139	[484]	[254,43,NaN]	-4	hSpCas9	negative selection	9966966
74620218	74620241	15	-	27869803	HPAFII	viability after 35 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-2.487495782001513	[650]	[62,53,NaN]	-8	hSpCas9	negative selection	9966967
74622179	74622202	15	-	27869803	HPAFII	viability after 35 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.623890434162602	[183]	[175,106,NaN]	4	hSpCas9	negative selection	9966968
74622513	74622536	15	+	27869803	HPAFII	viability after 35 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.0043394274297967605	[206]	[0,220,NaN]	0	hSpCas9	negative selection	9966969
74624920	74624943	15	+	27869803	HPAFII	viability after 35 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.6964411064843432	[1068]	[364,298,NaN]	-4	hSpCas9	negative selection	9966970
74615662	74615685	15	-	27869803	HPAFII	viability after 31 days	CCTAGGAGACTAGTTCCGGGAGG	CLK3	ENSG00000179335	-0.9732165354241509	[187]	[47,59,NaN]	-6	hSpCas9	negative selection	10049414
74619243	74619266	15	+	27869803	HPAFII	viability after 31 days	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.19885713322254928	[484]	[351,111,NaN]	-1	hSpCas9	negative selection	10049415
74620218	74620241	15	-	27869803	HPAFII	viability after 31 days	CTGGCTACCACTCACCGAGGAGG	CLK3	ENSG00000179335	-1.9277507231273425	[650]	[118,70,NaN]	-8	hSpCas9	negative selection	10049416
74622179	74622202	15	-	27869803	HPAFII	viability after 31 days	AATCGCCGATCCGGCACACCAGG	CLK3	ENSG00000179335	0.26881758402109635	[183]	[155,89,NaN]	2	hSpCas9	negative selection	10049417
74622513	74622536	15	+	27869803	HPAFII	viability after 31 days	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.6738246198650752	[206]	[12,137,NaN]	-4	hSpCas9	negative selection	10049418
74624920	74624943	15	+	27869803	HPAFII	viability after 31 days	CCTGAAGATCATCCGCAACGTGG	CLK3	ENSG00000179335	-0.8468848124837398	[1068]	[345,319,NaN]	-5	hSpCas9	negative selection	10049419
74619243	74619266	15	+	28162770	P31FUJ	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.24112898391803372	[89]	[124]	2	hSpCas9	negative selection	10134712
74629011	74629034	15	+	28162770	P31FUJ	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	0.1762613938198323	[362]	[481]	1	hSpCas9	negative selection	10134713
74620078	74620101	15	+	28162770	P31FUJ	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-0.6235921574465452	[117]	[89]	-5	hSpCas9	negative selection	10134714
74620200	74620223	15	-	28162770	P31FUJ	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.5132975803143949	[265]	[218]	-4	hSpCas9	negative selection	10134715
74622152	74622175	15	+	28162770	P31FUJ	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	0.003804076141770224	[201]	[237]	0	hSpCas9	negative selection	10134716
74622513	74622536	15	+	28162770	P31FUJ	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.9276624677788673	[84]	[189]	9	hSpCas9	negative selection	10134717
74625874	74625897	15	+	28162770	P31FUJ	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	0.3445870766019768	[190]	[284]	4	hSpCas9	negative selection	10134718
74627559	74627582	15	+	28162770	P31FUJ	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	0.598744181359977	[244]	[435]	6	hSpCas9	negative selection	10134719
74627621	74627644	15	-	28162770	P31FUJ	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.11338703746960777	[787]	[855]	-1	hSpCas9	negative selection	10134720
74628672	74628695	15	-	28162770	P31FUJ	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	0.030232201419415183	[24]	[29]	0	hSpCas9	negative selection	10134721
74619243	74619266	15	+	28162770	TF1	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10304078
74629011	74629034	15	+	28162770	TF1	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10304079
74620078	74620101	15	+	28162770	TF1	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10304080
74620200	74620223	15	-	28162770	TF1	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10304081
74622152	74622175	15	+	28162770	TF1	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10304082
74622513	74622536	15	+	28162770	TF1	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10304083
74625874	74625897	15	+	28162770	TF1	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10304084
74627559	74627582	15	+	28162770	TF1	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10304085
74627621	74627644	15	-	28162770	TF1	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	NaN	[NaN]	[646]	1	hSpCas9	negative selection	10304086
74628672	74628695	15	-	28162770	TF1	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10304087
74619243	74619266	15	+	28162770	SKM1	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.6927186810770389	[31]	[34]	-5	hSpCas9	negative selection	10473444
74629011	74629034	15	+	28162770	SKM1	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.2431393968372673	[78]	[58]	-7	hSpCas9	negative selection	10473445
74620078	74620101	15	+	28162770	SKM1	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	0.10399772053421774	[29]	[56]	1	hSpCas9	negative selection	10473446
74620200	74620223	15	-	28162770	SKM1	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.6776117886868306	[56]	[62]	-5	hSpCas9	negative selection	10473447
74622152	74622175	15	+	28162770	SKM1	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-0.9330330104107494	[80]	[74]	-6	hSpCas9	negative selection	10473448
74622513	74622536	15	+	28162770	SKM1	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.9824663702152518	[18]	[16]	-6	hSpCas9	negative selection	10473449
74625874	74625897	15	+	28162770	SKM1	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	0.7856808791992342	[41]	[127]	7	hSpCas9	negative selection	10473450
74627559	74627582	15	+	28162770	SKM1	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-0.8220016980220055	[61]	[61]	-6	hSpCas9	negative selection	10473451
74627621	74627644	15	-	28162770	SKM1	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-1.331556796085139	[204]	[143]	-7	hSpCas9	negative selection	10473452
74628672	74628695	15	-	28162770	SKM1	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-2.6293566200796095	[6]	[1]	-9	hSpCas9	negative selection	10473453
74619243	74619266	15	+	28162770	SKM1	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.6927186810770389	[31]	[34]	-5	hSpCas9	negative selection	10642810
74629011	74629034	15	+	28162770	SKM1	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.2431393968372673	[78]	[58]	-7	hSpCas9	negative selection	10642811
74620078	74620101	15	+	28162770	SKM1	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	0.10399772053421774	[29]	[56]	1	hSpCas9	negative selection	10642812
74620200	74620223	15	-	28162770	SKM1	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.6776117886868306	[56]	[62]	-5	hSpCas9	negative selection	10642813
74622152	74622175	15	+	28162770	SKM1	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-0.9330330104107494	[80]	[74]	-6	hSpCas9	negative selection	10642814
74622513	74622536	15	+	28162770	SKM1	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.9824663702152518	[18]	[16]	-6	hSpCas9	negative selection	10642815
74625874	74625897	15	+	28162770	SKM1	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	0.7856808791992342	[41]	[127]	7	hSpCas9	negative selection	10642816
74627559	74627582	15	+	28162770	SKM1	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-0.8220016980220055	[61]	[61]	-6	hSpCas9	negative selection	10642817
74627621	74627644	15	-	28162770	SKM1	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-1.331556796085139	[204]	[143]	-7	hSpCas9	negative selection	10642818
74628672	74628695	15	-	28162770	SKM1	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-2.6293566200796095	[6]	[1]	-9	hSpCas9	negative selection	10642819
74619243	74619266	15	+	28162770	PL21	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.18708346166387368	[110]	[54]	1	hSpCas9	negative selection	10812176
74629011	74629034	15	+	28162770	PL21	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-0.5209595742178652	[210]	[63]	-4	hSpCas9	negative selection	10812177
74620078	74620101	15	+	28162770	PL21	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-0.5628211882098304	[111]	[32]	-4	hSpCas9	negative selection	10812178
74620200	74620223	15	-	28162770	PL21	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.13658548232612297	[244]	[96]	-1	hSpCas9	negative selection	10812179
74622152	74622175	15	+	28162770	PL21	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-0.7998603855106798	[295]	[73]	-5	hSpCas9	negative selection	10812180
74622513	74622536	15	+	28162770	PL21	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	1.2261348230222644	[54]	[55]	8	hSpCas9	negative selection	10812181
74625874	74625897	15	+	28162770	PL21	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	0.6503053371717658	[141]	[96]	5	hSpCas9	negative selection	10812182
74627559	74627582	15	+	28162770	PL21	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	0.6759803928303638	[150]	[104]	6	hSpCas9	negative selection	10812183
74627621	74627644	15	-	28162770	PL21	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.15162370993880536	[512]	[200]	-1	hSpCas9	negative selection	10812184
74628672	74628695	15	-	28162770	PL21	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-2.384822886231836	[11]	[0]	-8	hSpCas9	negative selection	10812185
74619243	74619266	15	+	28162770	P31FUJ	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.24112898391803372	[89]	[124]	2	hSpCas9	negative selection	10981542
74629011	74629034	15	+	28162770	P31FUJ	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	0.1762613938198323	[362]	[481]	1	hSpCas9	negative selection	10981543
74620078	74620101	15	+	28162770	P31FUJ	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-0.6235921574465452	[117]	[89]	-5	hSpCas9	negative selection	10981544
74620200	74620223	15	-	28162770	P31FUJ	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.5132975803143949	[265]	[218]	-4	hSpCas9	negative selection	10981545
74622152	74622175	15	+	28162770	P31FUJ	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	0.003804076141770224	[201]	[237]	0	hSpCas9	negative selection	10981546
74622513	74622536	15	+	28162770	P31FUJ	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.9276624677788673	[84]	[189]	9	hSpCas9	negative selection	10981547
74625874	74625897	15	+	28162770	P31FUJ	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	0.3445870766019768	[190]	[284]	4	hSpCas9	negative selection	10981548
74627559	74627582	15	+	28162770	P31FUJ	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	0.598744181359977	[244]	[435]	6	hSpCas9	negative selection	10981549
74627621	74627644	15	-	28162770	P31FUJ	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.11338703746960777	[787]	[855]	-1	hSpCas9	negative selection	10981550
74628672	74628695	15	-	28162770	P31FUJ	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	0.030232201419415183	[24]	[29]	0	hSpCas9	negative selection	10981551
74619243	74619266	15	+	28162770	OCIAML5	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	0.3849726264368525	[41]	[98]	3	hSpCas9	negative selection	11150908
74629011	74629034	15	+	28162770	OCIAML5	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	0.010429905386068028	[186]	[339]	0	hSpCas9	negative selection	11150909
74620078	74620101	15	+	28162770	OCIAML5	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-1.2801602229682871	[73]	[54]	-6	hSpCas9	negative selection	11150910
74620200	74620223	15	-	28162770	OCIAML5	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.9369554684505099	[104]	[98]	-5	hSpCas9	negative selection	11150911
74622152	74622175	15	+	28162770	OCIAML5	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	0.26056228424690864	[116]	[252]	2	hSpCas9	negative selection	11150912
74622513	74622536	15	+	28162770	OCIAML5	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.5937545752726061	[50]	[60]	-4	hSpCas9	negative selection	11150913
74625874	74625897	15	+	28162770	OCIAML5	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-1.430426336760906	[108]	[72]	-7	hSpCas9	negative selection	11150914
74627559	74627582	15	+	28162770	OCIAML5	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	0.5904516648369538	[116]	[317]	5	hSpCas9	negative selection	11150915
74627621	74627644	15	-	28162770	OCIAML5	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.2308605495430116	[510]	[785]	-2	hSpCas9	negative selection	11150916
74628672	74628695	15	-	28162770	OCIAML5	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11150917
74619243	74619266	15	+	28162770	EOL1	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.12549291092906112	[175]	[84]	-1	hSpCas9	negative selection	11320274
74629011	74629034	15	+	28162770	EOL1	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.0524910799861544	[373]	[94]	-6	hSpCas9	negative selection	11320275
74620078	74620101	15	+	28162770	EOL1	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-2.224315614343948	[203]	[22]	-8	hSpCas9	negative selection	11320276
74620200	74620223	15	-	28162770	EOL1	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-1.8734084524848198	[458]	[65]	-8	hSpCas9	negative selection	11320277
74622152	74622175	15	+	28162770	EOL1	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-0.3680597496466065	[413]	[168]	-3	hSpCas9	negative selection	11320278
74622513	74622536	15	+	28162770	EOL1	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-1.5479399998922092	[110]	[19]	-7	hSpCas9	negative selection	11320279
74625874	74625897	15	+	28162770	EOL1	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-1.294620748891627	[148]	[31]	-7	hSpCas9	negative selection	11320280
74627559	74627582	15	+	28162770	EOL1	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-1.7513232253488318	[261]	[40]	-8	hSpCas9	negative selection	11320281
74627621	74627644	15	-	28162770	EOL1	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-2.5482732242939417	[865]	[77]	-8	hSpCas9	negative selection	11320282
74628672	74628695	15	-	28162770	EOL1	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-2.245377229871778	[17]	[1]	-8	hSpCas9	negative selection	11320283
74619243	74619266	15	+	28162770	MOLM13	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-2.0598482504836273	[172]	[29]	-7	hSpCas9	negative selection	11489640
74629011	74629034	15	+	28162770	MOLM13	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.060627972186834	[400]	[138]	-5	hSpCas9	negative selection	11489641
74620078	74620101	15	+	28162770	MOLM13	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	0.2879107154383434	[161]	[142]	2	hSpCas9	negative selection	11489642
74620200	74620223	15	-	28162770	MOLM13	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	0.5302377582123892	[316]	[330]	4	hSpCas9	negative selection	11489643
74622152	74622175	15	+	28162770	MOLM13	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-0.39586471068594176	[312]	[171]	-2	hSpCas9	negative selection	11489644
74622513	74622536	15	+	28162770	MOLM13	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	0.4678893815445788	[116]	[116]	3	hSpCas9	negative selection	11489645
74625874	74625897	15	+	28162770	MOLM13	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-1.64946756909358	[255]	[58]	-7	hSpCas9	negative selection	11489646
74627559	74627582	15	+	28162770	MOLM13	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-0.8867049022631056	[334]	[130]	-5	hSpCas9	negative selection	11489647
74627621	74627644	15	-	28162770	MOLM13	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-2.2545766429265126	[791]	[119]	-7	hSpCas9	negative selection	11489648
74628672	74628695	15	-	28162770	MOLM13	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-2.339465540513025	[20]	[2]	-8	hSpCas9	negative selection	11489649
74619243	74619266	15	+	28162770	HEL	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.972597317764318	[143]	[46]	-6	hSpCas9	negative selection	11659006
74629011	74629034	15	+	28162770	HEL	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.1957977453055268	[303]	[84]	-6	hSpCas9	negative selection	11659007
74620078	74620101	15	+	28162770	HEL	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-1.0020330639561028	[196]	[62]	-6	hSpCas9	negative selection	11659008
74620200	74620223	15	-	28162770	HEL	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.5285325951494722	[267]	[118]	-4	hSpCas9	negative selection	11659009
74622152	74622175	15	+	28162770	HEL	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-1.6791892628870053	[329]	[65]	-7	hSpCas9	negative selection	11659010
74622513	74622536	15	+	28162770	HEL	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.5362313090449624	[119]	[52]	-4	hSpCas9	negative selection	11659011
74625874	74625897	15	+	28162770	HEL	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-1.429211009878658	[184]	[43]	-7	hSpCas9	negative selection	11659012
74627559	74627582	15	+	28162770	HEL	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-1.8461967809470234	[246]	[43]	-7	hSpCas9	negative selection	11659013
74627621	74627644	15	-	28162770	HEL	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-2.2092600051120894	[721]	[99]	-8	hSpCas9	negative selection	11659014
74628672	74628695	15	-	28162770	HEL	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-4.527186169441956	[35]	[0]	-9	hSpCas9	negative selection	11659015
74619243	74619266	15	+	28162770	MV411	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.012206265850244424	[84]	[70]	0	hSpCas9	negative selection	11828372
74629011	74629034	15	+	28162770	MV411	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-2.60903513783952	[238]	[32]	-9	hSpCas9	negative selection	11828373
74620078	74620101	15	+	28162770	MV411	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-2.181405748021099	[139]	[25]	-8	hSpCas9	negative selection	11828374
74620200	74620223	15	-	28162770	MV411	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.25150120610501364	[235]	[166]	-2	hSpCas9	negative selection	11828375
74622152	74622175	15	+	28162770	MV411	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-1.1791879227712805	[249]	[92]	-6	hSpCas9	negative selection	11828376
74622513	74622536	15	+	28162770	MV411	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-2.811456138270793	[74]	[8]	-9	hSpCas9	negative selection	11828377
74625874	74625897	15	+	28162770	MV411	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-1.3498032797168176	[117]	[38]	-7	hSpCas9	negative selection	11828378
74627559	74627582	15	+	28162770	MV411	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-1.1282618005455678	[204]	[78]	-6	hSpCas9	negative selection	11828379
74627621	74627644	15	-	28162770	MV411	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-1.9172221344468952	[546]	[121]	-8	hSpCas9	negative selection	11828380
74628672	74628695	15	-	28162770	MV411	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-1.3375249499383806	[5]	[1]	-7	hSpCas9	negative selection	11828381
74619243	74619266	15	+	28162770	MONOMAC1	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.5678745424278626	[74]	[57]	-5	hSpCas9	negative selection	11997738
74629011	74629034	15	+	28162770	MONOMAC1	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.3765862673902665	[187]	[82]	-8	hSpCas9	negative selection	11997739
74620078	74620101	15	+	28162770	MONOMAC1	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-0.9917179390820472	[84]	[48]	-7	hSpCas9	negative selection	11997740
74620200	74620223	15	-	28162770	MONOMAC1	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.7390472025961631	[181]	[124]	-6	hSpCas9	negative selection	11997741
74622152	74622175	15	+	28162770	MONOMAC1	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-1.1653279873322153	[179]	[91]	-7	hSpCas9	negative selection	11997742
74622513	74622536	15	+	28162770	MONOMAC1	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.5725459821517602	[47]	[36]	-5	hSpCas9	negative selection	11997743
74625874	74625897	15	+	28162770	MONOMAC1	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-1.5125386727874828	[111]	[44]	-8	hSpCas9	negative selection	11997744
74627559	74627582	15	+	28162770	MONOMAC1	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-1.360535579342433	[111]	[49]	-7	hSpCas9	negative selection	11997745
74627621	74627644	15	-	28162770	MONOMAC1	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-1.4549926128555868	[396]	[165]	-8	hSpCas9	negative selection	11997746
74628672	74628695	15	-	28162770	MONOMAC1	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-0.897476565200646	[12]	[7]	-6	hSpCas9	negative selection	11997747
74619243	74619266	15	+	28162770	OCIAML2	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-1.2830028220663898	[35]	[81]	-7	hSpCas9	negative selection	12167104
74629011	74629034	15	+	28162770	OCIAML2	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-1.7001116713649285	[50]	[86]	-7	hSpCas9	negative selection	12167105
74620078	74620101	15	+	28162770	OCIAML2	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-2.0555923259633175	[32]	[43]	-8	hSpCas9	negative selection	12167106
74620200	74620223	15	-	28162770	OCIAML2	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.4531423985133203	[40]	[165]	-4	hSpCas9	negative selection	12167107
74622152	74622175	15	+	28162770	OCIAML2	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-0.4283190203841968	[41]	[172]	-3	hSpCas9	negative selection	12167108
74622513	74622536	15	+	28162770	OCIAML2	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-0.9180888022133824	[14]	[43]	-6	hSpCas9	negative selection	12167109
74625874	74625897	15	+	28162770	OCIAML2	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-0.9512556661485819	[29]	[85]	-6	hSpCas9	negative selection	12167110
74627559	74627582	15	+	28162770	OCIAML2	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	-2.240332205820367	[51]	[60]	-8	hSpCas9	negative selection	12167111
74627621	74627644	15	-	28162770	OCIAML2	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-1.9072004860706464	[89]	[132]	-8	hSpCas9	negative selection	12167112
74628672	74628695	15	-	28162770	OCIAML2	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	-1.8856673245210054	[1]	[2]	-8	hSpCas9	negative selection	12167113
74619243	74619266	15	+	28162770	OCIAML3	viability	TGAGCTACCGATGGAAGAGGAGG	CLK3	ENSG00000179335	-0.719538522408022	[17]	[32]	-5	hSpCas9	negative selection	12336470
74629011	74629034	15	+	28162770	OCIAML3	viability	GGAGAACTGCAAACCTCTGAAGG	CLK3	ENSG00000179335	-0.3689410846893897	[76]	[179]	-3	hSpCas9	negative selection	12336471
74620078	74620101	15	+	28162770	OCIAML3	viability	GCGGAGCCCATCCTTTGGAGAGG	CLK3	ENSG00000179335	-0.5509389184322773	[32]	[67]	-4	hSpCas9	negative selection	12336472
74620200	74620223	15	-	28162770	OCIAML3	viability	GGAGGCGCTGCTACAAGACCTGG	CLK3	ENSG00000179335	-0.6577332379345504	[80]	[154]	-5	hSpCas9	negative selection	12336473
74622152	74622175	15	+	28162770	OCIAML3	viability	GAGTGTGGAAGATGACAAGGAGG	CLK3	ENSG00000179335	-1.927431374049355	[62]	[49]	-8	hSpCas9	negative selection	12336474
74622513	74622536	15	+	28162770	OCIAML3	viability	GGGTGAAGGCACCTTTGGCAAGG	CLK3	ENSG00000179335	-1.8696420829375908	[22]	[18]	-8	hSpCas9	negative selection	12336475
74625874	74625897	15	+	28162770	OCIAML3	viability	GAACACCTTTGAGTTCCTGAAGG	CLK3	ENSG00000179335	-0.7956415014938137	[45]	[79]	-5	hSpCas9	negative selection	12336476
74627559	74627582	15	+	28162770	OCIAML3	viability	GAAGAACACCAGCATCCGAGTGG	CLK3	ENSG00000179335	0.21695853528581988	[56]	[199]	2	hSpCas9	negative selection	12336477
74627621	74627644	15	-	28162770	OCIAML3	viability	GTGACGGGTGGCCACAATGGTGG	CLK3	ENSG00000179335	-0.13542242537256244	[154]	[425]	-1	hSpCas9	negative selection	12336478
74628672	74628695	15	-	28162770	OCIAML3	viability	GGGGTCCTTACCTGGTACGGTGG	CLK3	ENSG00000179335	0.1064320778169292	[7]	[25]	1	hSpCas9	negative selection	12336479