Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:57396
• Symbol:CLK4
• Description:CDC like kinase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/CLK4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
178618621	178618644	5	+	26472758	Jiyoye	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	-0.0078621177729703	[371]	[278]	0	hSpCas9	negative selection	33396
178623294	178623317	5	-	26472758	Jiyoye	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.17778711921528284	[98]	[65]	-1	hSpCas9	negative selection	33397
178623361	178623384	5	-	26472758	Jiyoye	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.27789236456090705	[139]	[127]	2	hSpCas9	negative selection	33398
178623324	178623347	5	-	26472758	Jiyoye	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	1.2561094073148773	[170]	[307]	7	hSpCas9	negative selection	33399
178617420	178617443	5	-	26472758	Jiyoye	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	1.344439626157911	[46]	[89]	7	hSpCas9	negative selection	33400
178617398	178617421	5	-	26472758	Jiyoye	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	-0.09343784947904432	[190]	[134]	0	hSpCas9	negative selection	33401
178616896	178616919	5	+	26472758	Jiyoye	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	-0.08925044461362541	[78]	[55]	0	hSpCas9	negative selection	33402
178612425	178612448	5	-	26472758	Jiyoye	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	1.5311640987813266	[38]	[84]	8	hSpCas9	negative selection	33403
178623343	178623366	5	-	26472758	Jiyoye	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.20364198742074113	[227]	[197]	1	hSpCas9	negative selection	33404
178603843	178603866	5	-	26472758	Jiyoye	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.4071753815058734	[286]	[286]	3	hSpCas9	negative selection	33405
178618621	178618644	5	+	26472758	KBM7	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.13969022385917507	[1599,908]	[772,510]	1	hSpCas9	negative selection	224514
178623294	178623317	5	-	26472758	KBM7	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.3865770181342469	[345,381]	[146,118]	-4	hSpCas9	negative selection	224515
178623361	178623384	5	-	26472758	KBM7	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.7697438762098554	[521,501]	[616,227]	8	hSpCas9	negative selection	224516
178623324	178623347	5	-	26472758	KBM7	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.7284716156109131	[948,916]	[896,578]	7	hSpCas9	negative selection	224517
178617420	178617443	5	-	26472758	KBM7	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	0.3967763342930889	[237,252]	[177,130]	4	hSpCas9	negative selection	224518
178617398	178617421	5	-	26472758	KBM7	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.3099025171752003	[650,514]	[376,301]	3	hSpCas9	negative selection	224519
178616896	178616919	5	+	26472758	KBM7	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	-0.07627934845295892	[321,288]	[170,104]	0	hSpCas9	negative selection	224520
178612425	178612448	5	-	26472758	KBM7	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.7641495029421755	[415,206]	[223,256]	8	hSpCas9	negative selection	224521
178623343	178623366	5	-	26472758	KBM7	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.6416235634016774	[1015,893]	[805,603]	7	hSpCas9	negative selection	224522
178603843	178603866	5	-	26472758	KBM7	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.5821679958366182	[1341,1482]	[858,1133]	6	hSpCas9	negative selection	224523
178618621	178618644	5	+	26472758	Raji	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.5730471077224113	[419]	[144]	5	hSpCas9	negative selection	415632
178623294	178623317	5	-	26472758	Raji	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.11500888596284864	[139]	[29]	-1	hSpCas9	negative selection	415633
178623361	178623384	5	-	26472758	Raji	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.9273485062864459	[178]	[78]	8	hSpCas9	negative selection	415634
178623324	178623347	5	-	26472758	Raji	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.6969538172102996	[520]	[195]	6	hSpCas9	negative selection	415635
178617420	178617443	5	-	26472758	Raji	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	1.3506546863859634	[146]	[86]	9	hSpCas9	negative selection	415636
178617398	178617421	5	-	26472758	Raji	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.47935231276055723	[203]	[65]	4	hSpCas9	negative selection	415637
178616896	178616919	5	+	26472758	Raji	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.36014960575356647	[140]	[41]	3	hSpCas9	negative selection	415638
178612425	178612448	5	-	26472758	Raji	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.3159701571850168	[179]	[51]	3	hSpCas9	negative selection	415639
178623343	178623366	5	-	26472758	Raji	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.17624539351840374	[449]	[117]	1	hSpCas9	negative selection	415640
178603843	178603866	5	-	26472758	Raji	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.13024764372533637	[625]	[158]	1	hSpCas9	negative selection	415641
178618621	178618644	5	+	26472758	K562	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.47222464518925933	[835]	[978]	4	hSpCas9	negative selection	606750
178623294	178623317	5	-	26472758	K562	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.460958422757457	[246]	[286]	3	hSpCas9	negative selection	606751
178623361	178623384	5	-	26472758	K562	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.4779088578862254	[517]	[608]	4	hSpCas9	negative selection	606752
178623324	178623347	5	-	26472758	K562	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.6137814472228731	[1082]	[1398]	5	hSpCas9	negative selection	606753
178617420	178617443	5	-	26472758	K562	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	0.04278486649679647	[183]	[159]	0	hSpCas9	negative selection	606754
178617398	178617421	5	-	26472758	K562	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.8732355179770306	[431]	[667]	7	hSpCas9	negative selection	606755
178616896	178616919	5	+	26472758	K562	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.6594562269452905	[245]	[327]	5	hSpCas9	negative selection	606756
178612425	178612448	5	-	26472758	K562	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.25099138158993317	[218]	[219]	2	hSpCas9	negative selection	606757
178623343	178623366	5	-	26472758	K562	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.7240065425468735	[671]	[936]	6	hSpCas9	negative selection	606758
178603843	178603866	5	-	26472758	K562	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.6375870469847	[1129]	[1483]	5	hSpCas9	negative selection	606759
178612425	178612448	5	-	26627737	DLD1	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.8885922323570918	[733]	[479,379,413]	8	hSpCas9	negative selection	828343
178618730	178618753	5	-	26627737	DLD1	viability	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	1.2879296185169933	[166]	[72,178,131]	9	hSpCas9	negative selection	828344
178623330	178623353	5	-	26627737	DLD1	viability	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.49633818399170393	[447]	[103,84,106]	-5	hSpCas9	negative selection	828345
178623363	178623386	5	-	26627737	DLD1	viability	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	1.0072069992256214	[140]	[107,132,34]	8	hSpCas9	negative selection	828346
178612425	178612448	5	-	26627737	GBM cells	viability after 5 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.10404550059485851	[487]	[257,228]	-2	hSpCas9	negative selection	910658
178618730	178618753	5	-	26627737	GBM cells	viability after 5 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.04026972413122695	[203]	[121,102]	0	hSpCas9	negative selection	910659
178623330	178623353	5	-	26627737	GBM cells	viability after 5 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.46365620449902284	[287]	[106,116]	-6	hSpCas9	negative selection	910660
178623363	178623386	5	-	26627737	GBM cells	viability after 5 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.21250740778273758	[147]	[60,75]	-3	hSpCas9	negative selection	910661
178612425	178612448	5	-	26627737	GBM cells	viability after 13 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.38539006900982997	[487]	[237,173]	-4	hSpCas9	negative selection	992973
178618730	178618753	5	-	26627737	GBM cells	viability after 13 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.05411927949450651	[203]	[83,124]	0	hSpCas9	negative selection	992974
178623330	178623353	5	-	26627737	GBM cells	viability after 13 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.5232429527218176	[287]	[116,101]	-6	hSpCas9	negative selection	992975
178623363	178623386	5	-	26627737	GBM cells	viability after 13 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.29344145734187965	[147]	[75,56]	-4	hSpCas9	negative selection	992976
178612425	178612448	5	-	26627737	GBM cells	viability after 21 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.7772782746602186	[487]	[161,147]	-6	hSpCas9	negative selection	1075288
178618730	178618753	5	-	26627737	GBM cells	viability after 21 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.4462201294888175	[203]	[84,77]	-4	hSpCas9	negative selection	1075289
178623330	178623353	5	-	26627737	GBM cells	viability after 21 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.6919288039282241	[287]	[111,82]	-6	hSpCas9	negative selection	1075290
178623363	178623386	5	-	26627737	GBM cells	viability after 21 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.9779372512316168	[147]	[44,36]	-7	hSpCas9	negative selection	1075291
178612425	178612448	5	-	26627737	RPE1	viability after 9 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.6935495726027731	[1352]	[705,657]	4	hSpCas9	negative selection	1157603
178618730	178618753	5	-	26627737	RPE1	viability after 9 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	1.1655762269591143	[333]	[141,353]	7	hSpCas9	negative selection	1157604
178623330	178623353	5	-	26627737	RPE1	viability after 9 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.3372638815064139	[561]	[116,167]	-2	hSpCas9	negative selection	1157605
178623363	178623386	5	-	26627737	RPE1	viability after 9 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.13891933136395374	[490]	[160,111]	-1	hSpCas9	negative selection	1157606
178612425	178612448	5	-	26627737	RPE1	viability after 12 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.9890494372953799	[1352]	[670,774]	6	hSpCas9	negative selection	1239918
178618730	178618753	5	-	26627737	RPE1	viability after 12 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	1.266531088642489	[333]	[279,147]	7	hSpCas9	negative selection	1239919
178623330	178623353	5	-	26627737	RPE1	viability after 12 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.35881917721225526	[561]	[91,144]	-2	hSpCas9	negative selection	1239920
178623363	178623386	5	-	26627737	RPE1	viability after 12 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.5203539581088438	[490]	[107,74]	-4	hSpCas9	negative selection	1239921
178612425	178612448	5	-	26627737	RPE1	viability after 15 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	1.1657545931127342	[1352]	[989,731]	6	hSpCas9	negative selection	1322233
178618730	178618753	5	-	26627737	RPE1	viability after 15 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	1.1505015535746628	[333]	[139,276]	6	hSpCas9	negative selection	1322234
178623330	178623353	5	-	26627737	RPE1	viability after 15 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.46741447525258734	[561]	[115,113]	-3	hSpCas9	negative selection	1322235
178623363	178623386	5	-	26627737	RPE1	viability after 15 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.42958794409721024	[490]	[67,136]	-3	hSpCas9	negative selection	1322236
178612425	178612448	5	-	26627737	RPE1	viability after 18 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.3258954650550382	[1352]	[520,389]	2	hSpCas9	negative selection	1404548
178618730	178618753	5	-	26627737	RPE1	viability after 18 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.4216026719510141	[333]	[141,97]	2	hSpCas9	negative selection	1404549
178623330	178623353	5	-	26627737	RPE1	viability after 18 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.049470681663046356	[561]	[111,204]	0	hSpCas9	negative selection	1404550
178623363	178623386	5	-	26627737	RPE1	viability after 18 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.15027483393880414	[490]	[130,106]	-1	hSpCas9	negative selection	1404551
178612425	178612448	5	-	26627737	HeLa	viability after 8 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.42951547791465505	[1298]	[303,396,524]	-4	hSpCas9	negative selection	1486863
178618730	178618753	5	-	26627737	HeLa	viability after 8 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	1.1590482773611939	[158]	[55,233,151]	8	hSpCas9	negative selection	1486864
178623330	178623353	5	-	26627737	HeLa	viability after 8 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.049126547325385406	[446]	[304,111,208]	0	hSpCas9	negative selection	1486865
178623363	178623386	5	-	26627737	HeLa	viability after 8 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.4897738135891158	[221]	[203,126,93]	4	hSpCas9	negative selection	1486866
178612425	178612448	5	-	26627737	HeLa	viability after 12 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.5267675495225315	[1298]	[343,353,420]	-5	hSpCas9	negative selection	1569178
178618730	178618753	5	-	26627737	HeLa	viability after 12 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.8180733471539521	[158]	[49,168,120]	6	hSpCas9	negative selection	1569179
178623330	178623353	5	-	26627737	HeLa	viability after 12 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.37788309499794076	[446]	[233,86,113]	-3	hSpCas9	negative selection	1569180
178623363	178623386	5	-	26627737	HeLa	viability after 12 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.19785223346262482	[221]	[173,73,72]	1	hSpCas9	negative selection	1569181
178612425	178612448	5	-	26627737	HeLa	viability after 15 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.12110540099522726	[1298]	[705,177,578]	-1	hSpCas9	negative selection	1651493
178618730	178618753	5	-	26627737	HeLa	viability after 15 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.9993655777535144	[158]	[245,55,80]	7	hSpCas9	negative selection	1651494
178623330	178623353	5	-	26627737	HeLa	viability after 15 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.39031576292742626	[446]	[191,82,140]	-3	hSpCas9	negative selection	1651495
178623363	178623386	5	-	26627737	HeLa	viability after 15 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.751542980713606	[221]	[207,152,89]	6	hSpCas9	negative selection	1651496
178612425	178612448	5	-	26627737	HeLa	viability after 18 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.09123667154260029	[1298]	[488,152,578]	-1	hSpCas9	negative selection	1733808
178618730	178618753	5	-	26627737	HeLa	viability after 18 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.9518582405379048	[158]	[157,44,80]	7	hSpCas9	negative selection	1733809
178623330	178623353	5	-	26627737	HeLa	viability after 18 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.35551729416863254	[446]	[131,72,140]	-3	hSpCas9	negative selection	1733810
178623363	178623386	5	-	26627737	HeLa	viability after 18 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.7274006779700523	[221]	[131,129,89]	6	hSpCas9	negative selection	1733811
178612425	178612448	5	-	26627737	HCT116	viability after 6 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.6878076377818123	[1837]	[458,468]	4	hSpCas9	negative selection	1816123
178618730	178618753	5	-	26627737	HCT116	viability after 6 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.790884737779793	[440]	[12,54]	-4	hSpCas9	negative selection	1816124
178623330	178623353	5	-	26627737	HCT116	viability after 6 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.20572500088946938	[588]	[187,61]	1	hSpCas9	negative selection	1816125
178623363	178623386	5	-	26627737	HCT116	viability after 6 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	1.9751338993326604	[396]	[644,24]	8	hSpCas9	negative selection	1816126
178612425	178612448	5	-	26627737	HCT116	viability after 8 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.6343600511880925	[933]	[237,340,412]	-6	hSpCas9	negative selection	1898438
178618730	178618753	5	-	26627737	HCT116	viability after 8 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.4801024978281685	[285]	[131,152,54]	-5	hSpCas9	negative selection	1898439
178623330	178623353	5	-	26627737	HCT116	viability after 8 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.656168596706458	[341]	[128,116,112]	-7	hSpCas9	negative selection	1898440
178623363	178623386	5	-	26627737	HCT116	viability after 8 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.2021618779500484	[278]	[164,146,89]	-2	hSpCas9	negative selection	1898441
178612425	178612448	5	-	26627737	HCT116	viability after 9 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.12203407549667267	[1837]	[393,495]	-1	hSpCas9	negative selection	1980753
178618730	178618753	5	-	26627737	HCT116	viability after 9 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-2.4090319580959982	[440]	[10,30]	-9	hSpCas9	negative selection	1980754
178623330	178623353	5	-	26627737	HCT116	viability after 9 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.5855090368848492	[588]	[359,137]	4	hSpCas9	negative selection	1980755
178623363	178623386	5	-	26627737	HCT116	viability after 9 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.02769064664452414	[396]	[22,167]	0	hSpCas9	negative selection	1980756
178612425	178612448	5	-	26627737	HCT116	viability after 12 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.6545090275288329	[933]	[262,279,395]	-6	hSpCas9	negative selection	2063068
178618730	178618753	5	-	26627737	HCT116	viability after 12 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.14818342344029656	[285]	[134,137,133]	-1	hSpCas9	negative selection	2063069
178623330	178623353	5	-	26627737	HCT116	viability after 12 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.9068813173584942	[341]	[92,61,131]	-7	hSpCas9	negative selection	2063070
178623363	178623386	5	-	26627737	HCT116	viability after 12 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.6233053087053317	[278]	[74,122,89]	-6	hSpCas9	negative selection	2063071
178612425	178612448	5	-	26627737	HCT116	viability after 15 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.48987234673440216	[933]	[523,409,230]	-5	hSpCas9	negative selection	2145383
178618730	178618753	5	-	26627737	HCT116	viability after 15 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.4682908632958448	[285]	[76,147,125]	-5	hSpCas9	negative selection	2145384
178623330	178623353	5	-	26627737	HCT116	viability after 15 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.06667959811272842	[341]	[206,171,185]	0	hSpCas9	negative selection	2145385
178623363	178623386	5	-	26627737	HCT116	viability after 15 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.03776002765861766	[278]	[206,155,111]	0	hSpCas9	negative selection	2145386
178612425	178612448	5	-	26627737	HCT116	viability after 18 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.6833834219058892	[933]	[279,388,161]	-6	hSpCas9	negative selection	2227698
178618730	178618753	5	-	26627737	HCT116	viability after 18 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.9323829832876882	[285]	[65,60,91]	-7	hSpCas9	negative selection	2227699
178623330	178623353	5	-	26627737	HCT116	viability after 18 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.18127875921219536	[341]	[217,42,184]	-2	hSpCas9	negative selection	2227700
178623363	178623386	5	-	26627737	HCT116	viability after 18 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.10788349795425878	[278]	[87,237,101]	1	hSpCas9	negative selection	2227701
178618735	178618758	5	-	24336569	HL60	viability	CTTGAATGAGCGAGATTATCGGG	CLK4	ENSG00000113240	0.4809028710123677	[428]	[1266]	4	hSpCas9	negative selection	2258138
178618760	178618783	5	-	24336569	HL60	viability	GCAGTCATTATTTAGAAGCAAGG	CLK4	ENSG00000113240	-0.011790572822085066	[191]	[402]	0	hSpCas9	negative selection	2258139
178623254	178623277	5	+	24336569	HL60	viability	ACCAATCAGATTCTTTAAACTGG	CLK4	ENSG00000113240	0.5894083133200357	[564]	[1798]	5	hSpCas9	negative selection	2258140
178623262	178623285	5	+	24336569	HL60	viability	GATTCTTTAAACTGGTGATGTGG	CLK4	ENSG00000113240	0.8633303973476496	[292]	[1127]	7	hSpCas9	negative selection	2258141
178623294	178623317	5	-	24336569	HL60	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.48696983773508884	[1407]	[2125]	-4	hSpCas9	negative selection	2258142
178623324	178623347	5	-	24336569	HL60	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.11227811595080595	[1067]	[2442]	1	hSpCas9	negative selection	2258143
178623330	178623353	5	-	24336569	HL60	viability	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.609730462185913	[854]	[2760]	5	hSpCas9	negative selection	2258144
178623362	178623385	5	-	24336569	HL60	viability	TTGGGATAGCAGAGAAAGCTGGG	CLK4	ENSG00000113240	0.3883974233944689	[1064]	[2949]	3	hSpCas9	negative selection	2258145
178623367	178623390	5	+	24336569	HL60	viability	CTTTCTCTGCTATCCCAATCAGG	CLK4	ENSG00000113240	-0.6728243725482028	[112]	[149]	-6	hSpCas9	negative selection	2258146
178623380	178623403	5	-	24336569	HL60	viability	AAGAACTCACTGTCCTGATTGGG	CLK4	ENSG00000113240	1.1986438185638388	[370]	[1801]	8	hSpCas9	negative selection	2258147
178618735	178618758	5	-	24336569	KBM7	viability	CTTGAATGAGCGAGATTATCGGG	CLK4	ENSG00000113240	0.7738565304283104	[430]	[2009]	7	hSpCas9	negative selection	2325315
178618760	178618783	5	-	24336569	KBM7	viability	GCAGTCATTATTTAGAAGCAAGG	CLK4	ENSG00000113240	0.44884440000856723	[248]	[926]	4	hSpCas9	negative selection	2325316
178623254	178623277	5	+	24336569	KBM7	viability	ACCAATCAGATTCTTTAAACTGG	CLK4	ENSG00000113240	0.7039001375726115	[550]	[2447]	6	hSpCas9	negative selection	2325317
178623262	178623285	5	+	24336569	KBM7	viability	GATTCTTTAAACTGGTGATGTGG	CLK4	ENSG00000113240	0.06095789454588746	[490]	[1396]	0	hSpCas9	negative selection	2325318
178623294	178623317	5	-	24336569	KBM7	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.4050744814155194	[841]	[3040]	4	hSpCas9	negative selection	2325319
178623324	178623347	5	-	24336569	KBM7	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.3207366901647648	[1005]	[3426]	3	hSpCas9	negative selection	2325320
178623330	178623353	5	-	24336569	KBM7	viability	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.5845725212750337	[831]	[3402]	5	hSpCas9	negative selection	2325321
178623362	178623385	5	-	24336569	KBM7	viability	TTGGGATAGCAGAGAAAGCTGGG	CLK4	ENSG00000113240	0.7353456914588159	[846]	[3845]	6	hSpCas9	negative selection	2325322
178623367	178623390	5	+	24336569	KBM7	viability	CTTTCTCTGCTATCCCAATCAGG	CLK4	ENSG00000113240	1.1118482120651363	[18]	[111]	8	hSpCas9	negative selection	2325323
178623380	178623403	5	-	24336569	KBM7	viability	AAGAACTCACTGTCCTGATTGGG	CLK4	ENSG00000113240	0.8170270580413334	[343]	[1652]	7	hSpCas9	negative selection	2325324
178627173	178627196	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCTCGAGCCTCCACACTGCGG	CLK4	ENSG00000113240	1.6789319504273723	[151,44]	[126,6]	6	dCas9-VP64	positive selection	2452058
178627204	178627227	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGGGGGGTGGAAATGCTTGGG	CLK4	ENSG00000113240	-2.53365818709809	[51,41]	[0,0]	-9	dCas9-VP64	positive selection	2452059
178627140	178627163	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACGTGGAGCCCCGCCCTTAGG	CLK4	ENSG00000113240	-0.4076935552312131	[554,126]	[100,6]	-2	dCas9-VP64	positive selection	2452060
178627173	178627196	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCTCGAGCCTCCACACTGCGG	CLK4	ENSG00000113240	0.6735720364052233	[179,179]	[116,70]	5	dCas9-VP64	positive selection	2547313
178627204	178627227	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGGGGGGTGGAAATGCTTGGG	CLK4	ENSG00000113240	-1.2511778330205598	[263,68]	[26,18]	-9	dCas9-VP64	positive selection	2547314
178627140	178627163	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACGTGGAGCCCCGCCCTTAGG	CLK4	ENSG00000113240	1.0669268247322643	[132,140]	[162,28]	6	dCas9-VP64	positive selection	2547315
178618621	178618644	5	+	27013184	SW480	treatment with recombinant TRAIL	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	2.2872311704602852	[17,20]	[1,95]	8	hSpCas9	positive selection	2957821
178618662	178618685	5	+	27013184	SW480	treatment with recombinant TRAIL	ATGTCTCTGTGATAATGTCTAGG	CLK4	ENSG00000113240	0.45771767168449395	[690,352]	[231,440]	2	hSpCas9	positive selection	2957822
178623254	178623277	5	+	27013184	SW480	treatment with recombinant TRAIL	ACCAATCAGATTCTTTAAACTGG	CLK4	ENSG00000113240	-0.40858172947627036	[184,359]	[83,88]	-2	hSpCas9	positive selection	2957823
178623367	178623390	5	+	27013184	SW480	treatment with recombinant TRAIL	CTTTCTCTGCTATCCCAATCAGG	CLK4	ENSG00000113240	1.1760198670347055	[199,169]	[113,277]	5	hSpCas9	positive selection	2957824
178623384	178623407	5	+	27013184	SW480	treatment with recombinant TRAIL	ATCAGGACAGTGAGTTCTTTTGG	CLK4	ENSG00000113240	-0.6906711618762108	[348,423]	[87,122]	-3	hSpCas9	positive selection	2957825
178618546	178618569	5	-	27013184	SW480	treatment with recombinant TRAIL	TCAGTCACGTTCGGTATGATTGG	CLK4	ENSG00000113240	1.8575034008604605	[117,170]	[173,290]	8	hSpCas9	positive selection	2957826
178618555	178618578	5	-	27013184	SW480	treatment with recombinant TRAIL	TTCAAGTCATCAGTCACGTTCGG	CLK4	ENSG00000113240	-3.986578679124188	[130,284]	[2,8]	-9	hSpCas9	positive selection	2957827
178618613	178618636	5	-	27013184	SW480	treatment with recombinant TRAIL	GTAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	0.47199409185525454	[9,3]	[5,1]	2	hSpCas9	positive selection	2957828
178618711	178618734	5	+	27013184	SW480	treatment with recombinant TRAIL	TGTATTCGTCAACGTATCTCCGG	CLK4	ENSG00000113240	0.600551306081426	[67,31]	[8,68]	3	hSpCas9	positive selection	2957829
178618652	178618675	5	-	27013184	SW480	treatment with recombinant TRAIL	ATCACAGAGACATTGAAAGCGGG	CLK4	ENSG00000113240	-0.26829102871601335	[226,458]	[105,137]	-1	hSpCas9	positive selection	2957830
178618653	178618676	5	-	27013184	SW480	treatment with recombinant TRAIL	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	-0.3944172505938923	[49,247]	[31,65]	-2	hSpCas9	positive selection	2957831
178618692	178618715	5	-	27013184	SW480	treatment with recombinant TRAIL	TACAGGAATGACTACTGTGAAGG	CLK4	ENSG00000113240	-5.1611028527491	[81,265]	[1,1]	-9	hSpCas9	positive selection	2957832
178618709	178618732	5	-	27013184	SW480	treatment with recombinant TRAIL	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	2.7545545064919748	[198,175]	[496,622]	9	hSpCas9	positive selection	2957833
178618730	178618753	5	-	27013184	SW480	treatment with recombinant TRAIL	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.5876248826087228	[206,255]	[144,153]	3	hSpCas9	positive selection	2957834
178618735	178618758	5	-	27013184	SW480	treatment with recombinant TRAIL	CTTGAATGAGCGAGATTATCGGG	CLK4	ENSG00000113240	0.2936614163057353	[201,232]	[77,165]	1	hSpCas9	positive selection	2957835
178618736	178618759	5	-	27013184	SW480	treatment with recombinant TRAIL	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	2.4454813536021804	[134,184]	[400,327]	9	hSpCas9	positive selection	2957836
178618760	178618783	5	-	27013184	SW480	treatment with recombinant TRAIL	GCAGTCATTATTTAGAAGCAAGG	CLK4	ENSG00000113240	-0.027201221493676403	[173,192]	[52,111]	0	hSpCas9	positive selection	2957837
178616921	178616944	5	-	27013184	SW480	treatment with recombinant TRAIL	ATCGTGGACACTTTGGGTGAAGG	CLK4	ENSG00000113240	0.45078438301159574	[352,305]	[98,332]	2	hSpCas9	positive selection	2957838
178618736	178618759	5	+	27013184	SW480	treatment with recombinant TRAIL	CCGATAATCTCGCTCATTCAAGG	CLK4	ENSG00000113240	0.28147785539313386	[304,684]	[192,332]	1	hSpCas9	positive selection	2957839
178616927	178616950	5	-	27013184	SW480	treatment with recombinant TRAIL	GATGAAATCGTGGACACTTTGGG	CLK4	ENSG00000113240	0.19353834326452432	[167,319]	[55,203]	1	hSpCas9	positive selection	2957840
178616928	178616951	5	-	27013184	SW480	treatment with recombinant TRAIL	AGATGAAATCGTGGACACTTTGG	CLK4	ENSG00000113240	-0.9494591051020782	[127,202]	[8,74]	-4	hSpCas9	positive selection	2957841
178616937	178616960	5	-	27013184	SW480	treatment with recombinant TRAIL	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	1.1894864993662775	[127,193]	[240,33]	5	hSpCas9	positive selection	2957842
178623255	178623278	5	-	27013184	SW480	treatment with recombinant TRAIL	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	-4.824470060525022	[149,108]	[1,1]	-9	hSpCas9	positive selection	2957843
178623330	178623353	5	-	27013184	SW480	treatment with recombinant TRAIL	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.0951610483005716	[407,553]	[181,270]	0	hSpCas9	positive selection	2957844
178623343	178623366	5	-	27013184	SW480	treatment with recombinant TRAIL	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.49728937041613075	[193,328]	[54,110]	-2	hSpCas9	positive selection	2957845
178623380	178623403	5	-	27013184	SW480	treatment with recombinant TRAIL	AAGAACTCACTGTCCTGATTGGG	CLK4	ENSG00000113240	-0.528306066396053	[185,144]	[21,89]	-2	hSpCas9	positive selection	2957846
178623381	178623404	5	-	27013184	SW480	treatment with recombinant TRAIL	AAAGAACTCACTGTCCTGATTGG	CLK4	ENSG00000113240	-0.5540225472587049	[172,187]	[11,110]	-3	hSpCas9	positive selection	2957847
178623411	178623434	5	-	27013184	SW480	treatment with recombinant TRAIL	TTCATTTCTATCAACAGATGCGG	CLK4	ENSG00000113240	0.04595861821769187	[637,502]	[229,294]	0	hSpCas9	positive selection	2957848
178616937	178616960	5	+	27013184	SW480	treatment with recombinant TRAIL	CCACGATTTCATCTAGAGTGAGG	CLK4	ENSG00000113240	3.4367975522528718	[21,8]	[18,154]	9	hSpCas9	positive selection	2957849
178616940	178616963	5	+	27013184	SW480	treatment with recombinant TRAIL	CGATTTCATCTAGAGTGAGGAGG	CLK4	ENSG00000113240	-2.1712586031738343	[13,47]	[1,3]	-7	hSpCas9	positive selection	2957850
178617385	178617408	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTATAGAGGATGATGAGGAGGG	CLK4	ENSG00000113240	-0.04172324785497767	[3,3]	[2,2]	0	hSpCas9	positive selection	2979823
178613618	178613641	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTCTAGCATCTGGACACATCGG	CLK4	ENSG00000113240	-0.009918897154260892	[4,4]	[3,3]	0	hSpCas9	positive selection	2979824
178623330	178623353	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.09250411602045197	[3,2]	[2,2]	2	hSpCas9	positive selection	2979825
178618653	178618676	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	0.2429929628980778	[4,5]	[5,4]	5	hSpCas9	positive selection	2979826
178617385	178617408	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTATAGAGGATGATGAGGAGGG	CLK4	ENSG00000113240	-0.4460094398131116	[3,3]	[3,0]	-6	hSpCas9	positive selection	3047681
178613618	178613641	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTCTAGCATCTGGACACATCGG	CLK4	ENSG00000113240	-0.302045569991967	[4,4]	[2,1]	-4	hSpCas9	positive selection	3047682
178623330	178623353	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.23871080088676222	[3,3]	[2,1]	-4	hSpCas9	positive selection	3047683
178618653	178618676	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	0.12665012320591224	[4,4]	[5,2]	2	hSpCas9	positive selection	3047684
178623255	178623278		-	24336571	A375	resistance to PLX after 7 days	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.1438612552378091	[11,13]	[16,10]	4	hSpCas9	positive selection	3106122
178618736	178618759		+	24336571	A375	resistance to PLX after 7 days	CCGATAATCTCGCTCATTCAAGG	CLK4	ENSG00000113240	-0.28944288691308784	[17,16]	[14,12]	-8	hSpCas9	positive selection	3106123
178618709	178618732		-	24336571	A375	resistance to PLX after 7 days	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.11228776043711913	[15,16]	[16,17]	4	hSpCas9	positive selection	3106124
178623343	178623366		-	24336571	A375	resistance to PLX after 7 days	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.14034378298337802	[5,3]	[4,3]	-4	hSpCas9	positive selection	3106125
178623255	178623278		-	24336571	A375	resistance to PLX after 14 days	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	1.40398854309103	[11,10]	[12,15]	8	hSpCas9	positive selection	3163915
178618736	178618759		+	24336571	A375	resistance to PLX after 14 days	CCGATAATCTCGCTCATTCAAGG	CLK4	ENSG00000113240	-0.02640790410890806	[9,19]	[4,7]	0	hSpCas9	positive selection	3163916
178618709	178618732		-	24336571	A375	resistance to PLX after 14 days	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.06025523490790316	[9,14]	[5,4]	0	hSpCas9	positive selection	3163917
178623343	178623366		-	24336571	A375	resistance to PLX after 14 days	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.6442859177670527	[5,3]	[2,3]	6	hSpCas9	positive selection	3163918
178623255	178623278		-	24336571	A375	viability after 7 days	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	-0.5389021019854818	[19]	[11,13]	-6	hSpCas9	negative selection	3221708
178618736	178618759		+	24336571	A375	viability after 7 days	CCGATAATCTCGCTCATTCAAGG	CLK4	ENSG00000113240	-0.21017821659322866	[20]	[17,16]	-3	hSpCas9	negative selection	3221709
178618709	178618732		-	24336571	A375	viability after 7 days	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.019195155620494564	[16]	[15,16]	0	hSpCas9	negative selection	3221710
178623343	178623366		-	24336571	A375	viability after 7 days	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.30069078778387603	[6]	[5,3]	-4	hSpCas9	negative selection	3221711
178623255	178623278		-	24336571	A375	viability after 14 days	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	-0.6357084905435678	[19]	[11,10]	-6	hSpCas9	negative selection	3279501
178618736	178618759		+	24336571	A375	viability after 14 days	CCGATAATCTCGCTCATTCAAGG	CLK4	ENSG00000113240	-0.39584099951429297	[20]	[9,19]	-5	hSpCas9	negative selection	3279502
178618709	178618732		-	24336571	A375	viability after 14 days	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.35460401389574836	[16]	[9,14]	-4	hSpCas9	negative selection	3279503
178623343	178623366		-	24336571	A375	viability after 14 days	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.3012493708199091	[6]	[5,3]	-4	hSpCas9	negative selection	3279504
178618709	178618732	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.7064537064824601	[56,130]	[0,0]	3	hSpCas9	positive selection	3343575
178618736	178618759	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	-0.7315811993778559	[259,247]	[0,0]	-5	hSpCas9	positive selection	3343576
178623343	178623366	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.1721694192307853	[154,189]	[0,0]	-1	hSpCas9	positive selection	3343577
178616937	178616960	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.7370272254130229	[254,254]	[0,0]	-5	hSpCas9	positive selection	3362795
178623255	178623278	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	-0.29726264023180216	[187,187]	[0,0]	-2	hSpCas9	positive selection	3362796
178616885	178616908	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	0.5849008694743394	[101,101]	[0,0]	3	hSpCas9	positive selection	3362797
178617385	178617408	5	-	26780180	HT29	viability (Avana library 4 designs)	AGTATAGAGGATGATGAGGAGGG	CLK4	ENSG00000113240	1.86037780902486	[]	[]	7	hSpCas9	negative selection	3416256
178613617	178613640	5	+	26780180	HT29	viability (Avana library 4 designs)	ATTCTAGCATCTGGACACATCGG	CLK4	ENSG00000113240	1.27377942545604	[]	[]	5	hSpCas9	negative selection	3416257
178623330	178623353	5	-	26780180	HT29	viability (Avana library 4 designs)	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	2.78391099977681	[]	[]	8	hSpCas9	negative selection	3416258
178618653	178618676	5	-	26780180	HT29	viability (Avana library 4 designs)	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	0.156150894383431	[]	[]	0	hSpCas9	negative selection	3416259
178623330	178623353	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-3.21378447821812	[]	[]	-4	hSpCas9	negative selection	3493701
178618653	178618676	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	-5.82132750104645	[]	[]	-6	hSpCas9	negative selection	3493702
178613617	178613640	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTCTAGCATCTGGACACATCGG	CLK4	ENSG00000113240	-4.44360381432057	[]	[]	-5	hSpCas9	negative selection	3493703
178617385	178617408	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTATAGAGGATGATGAGGAGGG	CLK4	ENSG00000113240	-5.12102594398329	[]	[]	-5	hSpCas9	negative selection	3493704
178613773	178613796	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCTGAACGAGCTGCTTCACGG	CLK4	ENSG00000113240	1.28412488920803	[]	[]	1	hSpCas9	negative selection	3493705
178617398	178617421	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	-4.44868514351953	[]	[]	-5	hSpCas9	negative selection	3493706
178623330	178623353	5	-	26780180	A375	viability (Avana lentiGuide)	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-5.96993178560171	[]	[]	-8	hSpCas9	negative selection	3602360
178618653	178618676	5	-	26780180	A375	viability (Avana lentiGuide)	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	-1.23191617382384	[]	[]	-2	hSpCas9	negative selection	3602361
178613617	178613640	5	+	26780180	A375	viability (Avana lentiGuide)	ATTCTAGCATCTGGACACATCGG	CLK4	ENSG00000113240	-1.55946374948817	[]	[]	-3	hSpCas9	negative selection	3602362
178617385	178617408	5	-	26780180	A375	viability (Avana lentiGuide)	AGTATAGAGGATGATGAGGAGGG	CLK4	ENSG00000113240	3.49584620636597	[]	[]	3	hSpCas9	negative selection	3602363
178613773	178613796	5	+	26780180	A375	viability (Avana lentiGuide)	TTTCTGAACGAGCTGCTTCACGG	CLK4	ENSG00000113240	-1.54974245823401	[]	[]	-3	hSpCas9	negative selection	3602364
178617398	178617421	5	-	26780180	A375	viability (Avana lentiGuide)	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	-5.04313576835254	[]	[]	-8	hSpCas9	negative selection	3602365
178623330	178623353	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.0408761238223622	[4]	[5,4]	1	hSpCas9	positive selection	3711019
178618653	178618676	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	-0.42521158034211876	[7]	[5,4]	-6	hSpCas9	positive selection	3711020
178613617	178613640	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTCTAGCATCTGGACACATCGG	CLK4	ENSG00000113240	-0.22851519949364055	[6]	[5,4]	-4	hSpCas9	positive selection	3711021
178617385	178617408	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTATAGAGGATGATGAGGAGGG	CLK4	ENSG00000113240	-0.2585602753249014	[6]	[5,5]	-4	hSpCas9	positive selection	3711022
178613773	178613796	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCTGAACGAGCTGCTTCACGG	CLK4	ENSG00000113240	-0.00023896161695965978	[5]	[5,5]	0	hSpCas9	positive selection	3711023
178617398	178617421	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	-0.16344722036213932	[6]	[5,4]	-3	hSpCas9	positive selection	3711024
178623330	178623353	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.12804622386051995	[4]	[2,3]	-2	hSpCas9	positive selection	3819626
178618653	178618676	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCACAGAGACATTGAAAGCGG	CLK4	ENSG00000113240	-0.21597620931905168	[6]	[5,4]	-3	hSpCas9	positive selection	3819627
178613617	178613640	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTCTAGCATCTGGACACATCGG	CLK4	ENSG00000113240	0.19455580043547996	[6]	[6,5]	5	hSpCas9	positive selection	3819628
178617385	178617408	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTATAGAGGATGATGAGGAGGG	CLK4	ENSG00000113240	-0.07224888290244237	[5]	[4,4]	-1	hSpCas9	positive selection	3819629
178613773	178613796	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCTGAACGAGCTGCTTCACGG	CLK4	ENSG00000113240	0.3912751696597496	[5]	[6,6]	9	hSpCas9	positive selection	3819630
178617398	178617421	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	-0.010923396289880566	[4]	[5,2]	0	hSpCas9	positive selection	3819631
178623255	178623278	5	-	26780180	A375	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.466007901602692	[]	[]	1	hSpCas9	negative selection	3927622
178616937	178616960	5	-	26780180	A375	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.852195319692236	[]	[]	3	hSpCas9	negative selection	3927623
178618736	178618759	5	-	26780180	A375	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.225736396979612	[]	[]	0	hSpCas9	negative selection	3927624
178618709	178618732	5	-	26780180	A375	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	1.34633210480148	[]	[]	7	hSpCas9	negative selection	3927625
178616885	178616908	5	-	26780180	A375	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	1.23219828141747	[]	[]	6	hSpCas9	negative selection	3927626
178623343	178623366	5	-	26780180	A375	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	1.21143689001792	[]	[]	6	hSpCas9	negative selection	3927627
178623255	178623278	5	-	26780180	HT29	viability (GeCKOv2 library)	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	-0.168151470800894	[]	[]	-5	hSpCas9	negative selection	4035588
178616937	178616960	5	-	26780180	HT29	viability (GeCKOv2 library)	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	1.56539910676055	[]	[]	8	hSpCas9	negative selection	4035589
178618736	178618759	5	-	26780180	HT29	viability (GeCKOv2 library)	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.684806421601145	[]	[]	2	hSpCas9	negative selection	4035590
178618709	178618732	5	-	26780180	HT29	viability (GeCKOv2 library)	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	1.43665045464295	[]	[]	7	hSpCas9	negative selection	4035591
178616885	178616908	5	-	26780180	HT29	viability (GeCKOv2 library)	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	1.63088769953578	[]	[]	8	hSpCas9	negative selection	4035592
178623343	178623366	5	-	26780180	HT29	viability (GeCKOv2 library)	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.659368181137168	[]	[]	2	hSpCas9	negative selection	4035593
178623255	178623278	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.31460467178532087	[3]	[1,3]	7	hSpCas9	positive selection	4128262
178618736	178618759	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGATAATCTCGCTCATTCAAGG	CLK4	ENSG00000113240	-0.1591546235722486	[3]	[1,2]	-4	hSpCas9	positive selection	4128263
178618709	178618732	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.04044300633248369	[3]	[2,2]	-1	hSpCas9	positive selection	4128264
178623343	178623366	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.09094858355003549	[2]	[1,1]	2	hSpCas9	positive selection	4128265
178623255	178623278	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.8041020146676313	[3]	[0,1,4,3]	5	hSpCas9	positive selection	4192284
178618736	178618759	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGATAATCTCGCTCATTCAAGG	CLK4	ENSG00000113240	-0.33319149700027295	[4]	[2,1,0,0]	-5	hSpCas9	positive selection	4192285
178618709	178618732	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.16632700995943525	[3]	[1,0,2,0]	-2	hSpCas9	positive selection	4192286
178623343	178623366	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.14201097004748087	[1]	[0,1,0,0]	1	hSpCas9	positive selection	4192287
178618709	178618732	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.16233136001913076	[2]	[2,1]	-3	hSpCas9	positive selection	4263759
178618736	178618759	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.2672522948782242	[3]	[4,2]	5	hSpCas9	positive selection	4263760
178623343	178623366	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.08909449497904133	[3]	[3,1]	1	hSpCas9	positive selection	4263761
178616937	178616960	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.46248086837371605	[3]	[3,0]	-7	hSpCas9	positive selection	4328032
178623255	178623278	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.2638372967908707	[3]	[5,1]	5	hSpCas9	positive selection	4328033
178616885	178616908	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.49658437063765354	[2]	[1,0]	-8	hSpCas9	positive selection	4328034
178618613	178618635	5	-	27760321	OCIAML3	viability	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.18025159659634704	[825,745]	[426,691]	-2	hSpCas9	negative selection	4390063
178618709	178618731	5	-	27760321	OCIAML3	viability	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.6336476526208772	[112,108]	[117,156]	7	hSpCas9	negative selection	4390064
178618730	178618752	5	-	27760321	OCIAML3	viability	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.7847246234264544	[506,399]	[227,173]	-6	hSpCas9	negative selection	4390065
178623294	178623316	5	-	27760321	OCIAML3	viability	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-1.9506407177181422	[111,100]	[24,16]	-9	hSpCas9	negative selection	4390066
178616937	178616959	5	-	27760321	OCIAML3	viability	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.5868623901177671	[333,243]	[155,139]	-5	hSpCas9	negative selection	4390067
178618613	178618635	5	-	27760321	OCIAML2	viability	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.22304140217555357	[825,745]	[586,487]	-3	hSpCas9	negative selection	4473526
178618709	178618731	5	-	27760321	OCIAML2	viability	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-1.1068493607594567	[112,108]	[33,51]	-8	hSpCas9	negative selection	4473527
178618730	178618752	5	-	27760321	OCIAML2	viability	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.7774944549915607	[506,399]	[200,227]	-7	hSpCas9	negative selection	4473528
178623294	178623316	5	-	27760321	OCIAML2	viability	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.45582616110249363	[111,100]	[130,100]	6	hSpCas9	negative selection	4473529
178616937	178616959	5	-	27760321	OCIAML2	viability	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.2683888155136231	[333,243]	[290,262]	3	hSpCas9	negative selection	4473530
178618613	178618635	5	-	27760321	MV411	viability	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	0.5824491915802966	[825,745]	[986,458]	4	hSpCas9	negative selection	4556989
178618709	178618731	5	-	27760321	MV411	viability	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-1.4223880506962339	[112,108]	[0,66]	-7	hSpCas9	negative selection	4556990
178618730	178618752	5	-	27760321	MV411	viability	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.24751373263043985	[506,399]	[113,711]	1	hSpCas9	negative selection	4556991
178623294	178623316	5	-	27760321	MV411	viability	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-1.501229745563112	[111,100]	[27,19]	-7	hSpCas9	negative selection	4556992
178616937	178616959	5	-	27760321	MV411	viability	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.6899932232721161	[333,243]	[241,398]	5	hSpCas9	negative selection	4556993
178618613	178618635	5	-	27760321	HL60	viability	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.3923871633481543	[825,745]	[396,585]	-4	hSpCas9	negative selection	4640452
178618709	178618731	5	-	27760321	HL60	viability	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.3494382275083512	[112,108]	[47,95]	-4	hSpCas9	negative selection	4640453
178618730	178618752	5	-	27760321	HL60	viability	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.564588851721359	[506,399]	[277,217]	-6	hSpCas9	negative selection	4640454
178623294	178623316	5	-	27760321	HL60	viability	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.16263566048566114	[111,100]	[65,89]	-2	hSpCas9	negative selection	4640455
178616937	178616959	5	-	27760321	HL60	viability	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.22336338205326922	[333,243]	[222,325]	2	hSpCas9	negative selection	4640456
178618613	178618635	5	-	27760321	HT1080	viability	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-2.90589053803615	[745,581]	[51,16]	-7	hSpCas9	negative selection	4723915
178618709	178618731	5	-	27760321	HT1080	viability	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	2.6114943567424826	[108,84]	[333,128]	9	hSpCas9	negative selection	4723916
178618730	178618752	5	-	27760321	HT1080	viability	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.89511548984032	[399,311]	[49,104]	-4	hSpCas9	negative selection	4723917
178623294	178623316	5	-	27760321	HT1080	viability	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.13706499732008215	[100,78]	[37,40]	0	hSpCas9	negative selection	4723918
178616937	178616959	5	-	27760321	HT1080	viability	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	1.7134003044524821	[243,190]	[361,198]	8	hSpCas9	negative selection	4723919
178618613	178618635	5	-	27760321	HT29	viability after 7 days	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	0.012185923742740745	[745,581]	[767,897,900]	0	hSpCas9	negative selection	4807378
178618709	178618731	5	-	27760321	HT29	viability after 7 days	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-2.300974309019927	[108,84]	[42,28,6]	-9	hSpCas9	negative selection	4807379
178618730	178618752	5	-	27760321	HT29	viability after 7 days	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.4388368273437696	[399,311]	[181,397,407]	-6	hSpCas9	negative selection	4807380
178623294	178623316	5	-	27760321	HT29	viability after 7 days	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.8288261503307106	[100,78]	[23,147,18]	-8	hSpCas9	negative selection	4807381
178616937	178616959	5	-	27760321	HT29	viability after 7 days	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.05779890143268762	[243,190]	[350,318,213]	0	hSpCas9	negative selection	4807382
178618613	178618635	5	-	27760321	HT29	viability after 25 days	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	0.026684936769756584	[745,581]	[678,1006,621]	0	hSpCas9	negative selection	4890841
178618709	178618731	5	-	27760321	HT29	viability after 25 days	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.9572541094535572	[108,84]	[57,82,26]	-6	hSpCas9	negative selection	4890842
178618730	178618752	5	-	27760321	HT29	viability after 25 days	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.44155746893583353	[399,311]	[207,430,260]	-4	hSpCas9	negative selection	4890843
178623294	178623316	5	-	27760321	HT29	viability after 25 days	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.2354909562546037	[100,78]	[18,242,105]	2	hSpCas9	negative selection	4890844
178616937	178616959	5	-	27760321	HT29	viability after 25 days	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.03913969971951092	[243,190]	[202,273,251]	0	hSpCas9	negative selection	4890845
178618613	178618635	5	-	27760321	HT29	viability after 22 days	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	0.12183174827686294	[745,581]	[871,972,657]	1	hSpCas9	negative selection	4974304
178618709	178618731	5	-	27760321	HT29	viability after 22 days	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-1.2343223652696613	[108,84]	[76,36,27]	-7	hSpCas9	negative selection	4974305
178618730	178618752	5	-	27760321	HT29	viability after 22 days	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.38865697950145	[399,311]	[155,509,280]	-4	hSpCas9	negative selection	4974306
178623294	178623316	5	-	27760321	HT29	viability after 22 days	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.20011136632577808	[100,78]	[24,106,141]	-2	hSpCas9	negative selection	4974307
178616937	178616959	5	-	27760321	HT29	viability after 22 days	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.08912662069070632	[243,190]	[207,342,252]	0	hSpCas9	negative selection	4974308
178618613	178618635	5	-	27760321	HT29	viability after 19 days	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.3673520286863894	[745,581]	[775,440,568]	-3	hSpCas9	negative selection	5057767
178618709	178618731	5	-	27760321	HT29	viability after 19 days	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-1.2716518866771453	[108,84]	[44,0,89]	-7	hSpCas9	negative selection	5057768
178618730	178618752	5	-	27760321	HT29	viability after 19 days	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.18850702833636318	[399,311]	[387,514,479]	1	hSpCas9	negative selection	5057769
178623294	178623316	5	-	27760321	HT29	viability after 19 days	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.10980448059707015	[100,78]	[31,237,56]	1	hSpCas9	negative selection	5057770
178616937	178616959	5	-	27760321	HT29	viability after 19 days	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.3035954296999946	[243,190]	[305,310,303]	3	hSpCas9	negative selection	5057771
178618613	178618635	5	-	27760321	HT29	viability after 16 days	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.035746321555606086	[745,581]	[639,760,763]	0	hSpCas9	negative selection	5141230
178618709	178618731	5	-	27760321	HT29	viability after 16 days	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.5831559038622225	[108,84]	[107,20,92]	-5	hSpCas9	negative selection	5141231
178618730	178618752	5	-	27760321	HT29	viability after 16 days	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.3089754391077577	[399,311]	[316,436,206]	-3	hSpCas9	negative selection	5141232
178623294	178623316	5	-	27760321	HT29	viability after 16 days	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.2864617036590069	[100,78]	[10,194,31]	-3	hSpCas9	negative selection	5141233
178616937	178616959	5	-	27760321	HT29	viability after 16 days	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.09067011735048813	[243,190]	[318,263,199]	0	hSpCas9	negative selection	5141234
178618613	178618635	5	-	27760321	HT29	viability after 13 days	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.14579161177159183	[745,581]	[929,681,488]	-2	hSpCas9	negative selection	5224693
178618709	178618731	5	-	27760321	HT29	viability after 13 days	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-1.069790090421959	[108,84]	[37,105,18]	-7	hSpCas9	negative selection	5224694
178618730	178618752	5	-	27760321	HT29	viability after 13 days	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.29328025391517176	[399,311]	[210,594,212]	-4	hSpCas9	negative selection	5224695
178623294	178623316	5	-	27760321	HT29	viability after 13 days	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.12153392007591934	[100,78]	[118,77,141]	1	hSpCas9	negative selection	5224696
178616937	178616959	5	-	27760321	HT29	viability after 13 days	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.23408464698956488	[243,190]	[232,367,289]	3	hSpCas9	negative selection	5224697
178618613	178618635	5	-	27760321	HT29	viability after 10 days	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.13972962210594553	[745,581]	[526,725,997]	-2	hSpCas9	negative selection	5308156
178618709	178618731	5	-	27760321	HT29	viability after 10 days	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.007583345010833353	[108,84]	[45,125,187]	0	hSpCas9	negative selection	5308157
178618730	178618752	5	-	27760321	HT29	viability after 10 days	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-1.143591209751018	[399,311]	[146,114,335]	-8	hSpCas9	negative selection	5308158
178623294	178623316	5	-	27760321	HT29	viability after 10 days	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.29603013279458135	[100,78]	[92,98,82]	-4	hSpCas9	negative selection	5308159
178616937	178616959	5	-	27760321	HT29	viability after 10 days	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.13285364175138092	[243,190]	[344,248,297]	1	hSpCas9	negative selection	5308160
178618613	178618635	5	-	27760321	MOLM13	viability	TAAATCTTCAGTCCGCAGCAGG	CLK4	ENSG00000113240	-0.017063056909067953	[825,745]	[533,355]	0	hSpCas9	negative selection	5391619
178618709	178618731	5	-	27760321	MOLM13	viability	GAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.7979383259875317	[112,108]	[181,46]	5	hSpCas9	negative selection	5391620
178618730	178618752	5	-	27760321	MOLM13	viability	TGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.7877337290105014	[506,399]	[426,448]	5	hSpCas9	negative selection	5391621
178623294	178623316	5	-	27760321	MOLM13	viability	TAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.2749068134082715	[111,100]	[0,90]	-2	hSpCas9	negative selection	5391622
178616937	178616959	5	-	27760321	MOLM13	viability	CTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.11210883860705145	[333,243]	[193,157]	0	hSpCas9	negative selection	5391623
178626542	178626565	5	+	27661255	K562	viability	GGCCCAGGCCAGGAATCCAGGGG	CLK4	ENSG00000113240	0.10440108345688093	[1023,1053]	[921,865]	3	dCas9-KRAB	negative selection	5471508
178626639	178626662	5	+	27661255	K562	viability	GGCTGGAAGAGGTCCCGACAGGG	CLK4	ENSG00000113240	0.08070636261721753	[556,656]	[507,513]	3	dCas9-KRAB	negative selection	5471509
178627015	178627038	5	+	27661255	K562	viability	GCGACAAACACCCCACAAAATGG	CLK4	ENSG00000113240	0.2185017621397749	[206,190]	[188,181]	7	dCas9-KRAB	negative selection	5471510
178626616	178626639	5	-	27661255	K562	viability	GGCGGGCGCTAGGACCTGTCGGG	CLK4	ENSG00000113240	0.17474407350555157	[576,566]	[550,485]	6	dCas9-KRAB	negative selection	5471511
178618709	178618732	5	-	27260156	BXPC3	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.06193715689533261	[410]	[346,341,487,488]	-1	hSpCas9	negative selection	5536219
178618736	178618759	5	-	27260156	BXPC3	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.39180050189672144	[911]	[1198,1320,1212,1264]	8	hSpCas9	negative selection	5536220
178623343	178623366	5	-	27260156	BXPC3	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.18240821719689587	[617]	[552,716,828,867]	4	hSpCas9	negative selection	5536221
178616937	178616960	5	-	27260156	BXPC3	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.2872685674012109	[623]	[546,485,518,590]	-6	hSpCas9	negative selection	5600492
178623255	178623278	5	-	27260156	BXPC3	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.5588516471551725	[536]	[731,839,763,995]	9	hSpCas9	negative selection	5600493
178616885	178616908	5	-	27260156	BXPC3	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.1940871819419574	[240]	[188,120,314,271]	-4	hSpCas9	negative selection	5600494
178618709	178618732	5	-	27260156	A673	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.20241069372953965	[410]	[478,337,424,483]	-5	hSpCas9	negative selection	5657470
178618736	178618759	5	-	27260156	A673	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.16017459138995926	[911]	[1403,1035,1072,1416]	4	hSpCas9	negative selection	5657471
178623343	178623366	5	-	27260156	A673	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.17550761792735642	[617]	[850,795,762,949]	4	hSpCas9	negative selection	5657472
178616937	178616960	5	-	27260156	A673	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.12074876586763011	[623]	[781,751,562,666]	-3	hSpCas9	negative selection	5721743
178623255	178623278	5	-	27260156	A673	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.3162102119478102	[536]	[809,823,716,862]	7	hSpCas9	negative selection	5721744
178616885	178616908	5	-	27260156	A673	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.4539739983930655	[240]	[265,266,111,204]	-8	hSpCas9	negative selection	5721745
178618709	178618732	5	-	27260156	A375	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.4258206314922355	[410]	[373,598,253,247]	-5	hSpCas9	negative selection	5778721
178618736	178618759	5	-	27260156	A375	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.6479374327350342	[911]	[1825,1827,1756,1323]	8	hSpCas9	negative selection	5778722
178623343	178623366	5	-	27260156	A375	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.13452932325319528	[617]	[741,908,699,826]	2	hSpCas9	negative selection	5778723
178616937	178616960	5	-	27260156	A375	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.2162616466223192	[623]	[566,788,535,635]	-3	hSpCas9	negative selection	5842994
178623255	178623278	5	-	27260156	A375	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.45736741936012903	[536]	[997,867,777,805]	6	hSpCas9	negative selection	5842995
178616885	178616908	5	-	27260156	A375	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.3409606379474228	[240]	[237,162,330,155]	-5	hSpCas9	negative selection	5842996
178618709	178618732	5	-	27260156	COLO741	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.12621502087527295	[410]	[524,439,480]	-3	hSpCas9	negative selection	5899972
178618736	178618759	5	-	27260156	COLO741	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.26712328833142474	[911]	[1565,1314,1340]	5	hSpCas9	negative selection	5899973
178623343	178623366	5	-	27260156	COLO741	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.28308776953738196	[617]	[1120,901,876]	6	hSpCas9	negative selection	5899974
178616937	178616960	5	-	27260156	COLO741	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.5088216109181544	[623]	[524,607,544]	-8	hSpCas9	negative selection	5964245
178623255	178623278	5	-	27260156	COLO741	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.30970566082398	[536]	[1017,830,723]	6	hSpCas9	negative selection	5964246
178616885	178616908	5	-	27260156	COLO741	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.3558893178467768	[240]	[246,180,289]	-6	hSpCas9	negative selection	5964247
178618709	178618732	5	-	27260156	CAL120	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.21763668416107726	[410]	[796,189,386]	-3	hSpCas9	negative selection	6021223
178618736	178618759	5	-	27260156	CAL120	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.6792676876285944	[911]	[1953,1769,1748]	8	hSpCas9	negative selection	6021224
178623343	178623366	5	-	27260156	CAL120	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.10591042313823673	[617]	[909,609,653]	-1	hSpCas9	negative selection	6021225
178616937	178616960	5	-	27260156	CAL120	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.18049572413989073	[623]	[699,644,711]	-3	hSpCas9	negative selection	6085496
178623255	178623278	5	-	27260156	CAL120	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.5456501755857044	[536]	[1296,801,876]	7	hSpCas9	negative selection	6085497
178616885	178616908	5	-	27260156	CAL120	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.9753624417841606	[240]	[168,137,152]	-8	hSpCas9	negative selection	6085498
178618709	178618732	5	-	27260156	CADOES1	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.20003870524198744	[410]	[337,411,304,273]	-3	hSpCas9	negative selection	6142474
178618736	178618759	5	-	27260156	CADOES1	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.47196761856383995	[911]	[1282,1186,1126,1105]	7	hSpCas9	negative selection	6142475
178623343	178623366	5	-	27260156	CADOES1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.2849988783449608	[617]	[738,859,642,553]	5	hSpCas9	negative selection	6142476
178616937	178616960	5	-	27260156	CADOES1	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.09444145078656657	[623]	[405,730,470,567]	-2	hSpCas9	negative selection	6206747
178623255	178623278	5	-	27260156	CADOES1	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.45720099154752725	[536]	[632,688,602,822]	7	hSpCas9	negative selection	6206748
178616885	178616908	5	-	27260156	CADOES1	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.2967392752635365	[240]	[163,184,196,183]	-5	hSpCas9	negative selection	6206749
178618709	178618732	5	-	27260156	EWS502	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.12738564142702433	[410]	[293,343,539,433]	-2	hSpCas9	negative selection	6263725
178618736	178618759	5	-	27260156	EWS502	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.4170768139058345	[911]	[1048,1429,1334,1369]	7	hSpCas9	negative selection	6263726
178623343	178623366	5	-	27260156	EWS502	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.06067569704565018	[617]	[617,662,571,655]	-1	hSpCas9	negative selection	6263727
178616937	178616960	5	-	27260156	EWS502	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.06195656219442225	[623]	[547,636,683,674]	-1	hSpCas9	negative selection	6327998
178623255	178623278	5	-	27260156	EWS502	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.31261119863084896	[536]	[773,653,688,698]	5	hSpCas9	negative selection	6327999
178616885	178616908	5	-	27260156	EWS502	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.4204189182597864	[240]	[76,220,272,205]	-6	hSpCas9	negative selection	6328000
178618709	178618732	5	-	27260156	EW8	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.09900116030464187	[410]	[318,402,212,325]	-2	hSpCas9	negative selection	6384976
178618736	178618759	5	-	27260156	EW8	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.4422967409633578	[911]	[1047,1293,807,903]	7	hSpCas9	negative selection	6384977
178623343	178623366	5	-	27260156	EW8	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.10209513648248947	[617]	[717,539,447,477]	1	hSpCas9	negative selection	6384978
178616937	178616960	5	-	27260156	EW8	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.20926849228377542	[623]	[586,456,343,392]	-4	hSpCas9	negative selection	6449249
178623255	178623278	5	-	27260156	EW8	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.32184852599048275	[536]	[467,801,397,523]	6	hSpCas9	negative selection	6449250
178616885	178616908	5	-	27260156	EW8	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.34875066872544846	[240]	[111,184,126,188]	-6	hSpCas9	negative selection	6449251
178618709	178618732	5	-	27260156	CORL105	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.14481497844759622	[410]	[546,343,849,440]	2	hSpCas9	negative selection	6506227
178618736	178618759	5	-	27260156	CORL105	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.4478019475083983	[911]	[1518,1365,1366,1561]	7	hSpCas9	negative selection	6506228
178623343	178623366	5	-	27260156	CORL105	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.041301748793751425	[617]	[801,707,778,696]	0	hSpCas9	negative selection	6506229
178616937	178616960	5	-	27260156	CORL105	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.035313833820882934	[623]	[907,792,622,518]	0	hSpCas9	negative selection	6570500
178623255	178623278	5	-	27260156	CORL105	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.34123111593680755	[536]	[814,678,940,775]	6	hSpCas9	negative selection	6570501
178616885	178616908	5	-	27260156	CORL105	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.3937882346794106	[240]	[191,261,212,189]	-6	hSpCas9	negative selection	6570502
178618709	178618732	5	-	27260156	HS294T	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.626503277725743	[410]	[98,91,83,143]	-7	hSpCas9	negative selection	6627478
178618736	178618759	5	-	27260156	HS294T	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.18310848335161078	[911]	[280,369,419,569]	2	hSpCas9	negative selection	6627479
178623343	178623366	5	-	27260156	HS294T	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.5556441819215694	[617]	[284,532,198,393]	7	hSpCas9	negative selection	6627480
178616937	178616960	5	-	27260156	HS294T	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.4310323877209146	[623]	[217,139,687,259]	6	hSpCas9	negative selection	6691751
178623255	178623278	5	-	27260156	HS294T	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.2050918661737286	[536]	[288,239,181,240]	2	hSpCas9	negative selection	6691752
178616885	178616908	5	-	27260156	HS294T	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	0.12319389145551007	[240]	[47,103,135,126]	1	hSpCas9	negative selection	6691753
178618709	178618732	5	-	27260156	HCC44	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.2661419163580346	[410]	[678,559,478,511]	4	hSpCas9	negative selection	6748729
178618736	178618759	5	-	27260156	HCC44	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.45852719034425227	[911]	[1603,883,2073,1305]	7	hSpCas9	negative selection	6748730
178623343	178623366	5	-	27260156	HCC44	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.009235503989579397	[617]	[625,432,1142,712]	0	hSpCas9	negative selection	6748731
178616937	178616960	5	-	27260156	HCC44	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.3863138954370373	[623]	[640,447,557,533]	-6	hSpCas9	negative selection	6813002
178623255	178623278	5	-	27260156	HCC44	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.5627847336759672	[536]	[1230,681,1130,646]	8	hSpCas9	negative selection	6813003
178616885	178616908	5	-	27260156	HCC44	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.47901482985353705	[240]	[160,238,180,187]	-6	hSpCas9	negative selection	6813004
178618709	178618732	5	-	27260156	G402	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.46060041536396645	[410]	[552,617,1045,524]	6	hSpCas9	negative selection	6869980
178618736	178618759	5	-	27260156	G402	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.5292670434941253	[911]	[1623,1721,1873,1225]	6	hSpCas9	negative selection	6869981
178623343	178623366	5	-	27260156	G402	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.07868999813066513	[617]	[1508,678,496,602]	1	hSpCas9	negative selection	6869982
178616937	178616960	5	-	27260156	G402	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.09349942604000311	[623]	[1223,940,816,353]	1	hSpCas9	negative selection	6934253
178623255	178623278	5	-	27260156	G402	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.3030707229849574	[536]	[1197,541,715,814]	4	hSpCas9	negative selection	6934254
178616885	178616908	5	-	27260156	G402	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.4967458720773339	[240]	[150,340,253,91]	-6	hSpCas9	negative selection	6934255
178618709	178618732	5	-	27260156	L33	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.2379837446320289	[410]	[250,181,265,278]	-5	hSpCas9	negative selection	6991231
178618736	178618759	5	-	27260156	L33	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.21101910334513185	[911]	[1012,437,617,1156]	4	hSpCas9	negative selection	6991232
178623343	178623366	5	-	27260156	L33	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.04035436111218821	[617]	[545,308,399,607]	0	hSpCas9	negative selection	6991233
178616937	178616960	5	-	27260156	L33	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.37284990096591775	[623]	[482,212,279,478]	-7	hSpCas9	negative selection	7055504
178623255	178623278	5	-	27260156	L33	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.21363485767006768	[536]	[576,257,423,610]	4	hSpCas9	negative selection	7055505
178616885	178616908	5	-	27260156	L33	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.13475168273447324	[240]	[214,84,151,213]	-3	hSpCas9	negative selection	7055506
178618709	178618732	5	-	27260156	K562	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.4912833950289982	[410]	[343,146,279,265]	-5	hSpCas9	negative selection	7112482
178618736	178618759	5	-	27260156	K562	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.42099120383564625	[911]	[969,982,1173,1176]	5	hSpCas9	negative selection	7112483
178623343	178623366	5	-	27260156	K562	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.18982986800870877	[617]	[613,432,650,772]	2	hSpCas9	negative selection	7112484
178616937	178616960	5	-	27260156	K562	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.047821326609784054	[623]	[656,698,628,342]	0	hSpCas9	negative selection	7176755
178623255	178623278	5	-	27260156	K562	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.6222471300228081	[536]	[450,678,946,817]	7	hSpCas9	negative selection	7176756
178616885	178616908	5	-	27260156	K562	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.3321071909425459	[240]	[278,54,217,133]	-4	hSpCas9	negative selection	7176757
178618709	178618732	5	-	27260156	HT29	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.35646555710766537	[410]	[377,477,392,323]	-6	hSpCas9	negative selection	7233733
178618736	178618759	5	-	27260156	HT29	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.35158154246196816	[911]	[1380,1644,1294,1351]	7	hSpCas9	negative selection	7233734
178623343	178623366	5	-	27260156	HT29	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.14142763621772753	[617]	[873,838,736,858]	2	hSpCas9	negative selection	7233735
178616937	178616960	5	-	27260156	HT29	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.014942612358968044	[623]	[982,670,579,826]	0	hSpCas9	negative selection	7298006
178623255	178623278	5	-	27260156	HT29	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.5995712164814085	[536]	[1155,1151,946,750]	9	hSpCas9	negative selection	7298007
178616885	178616908	5	-	27260156	HT29	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.25965657110467877	[240]	[300,199,244,232]	-5	hSpCas9	negative selection	7298008
178618709	178618732	5	-	27260156	MHHES1	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.4319706182662527	[410]	[308,442,284,334]	-7	hSpCas9	negative selection	7354984
178618736	178618759	5	-	27260156	MHHES1	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.10442163721217512	[911]	[1267,1142,1193,866]	2	hSpCas9	negative selection	7354985
178623343	178623366	5	-	27260156	MHHES1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.030125050743128712	[617]	[783,441,816,754]	0	hSpCas9	negative selection	7354986
178616937	178616960	5	-	27260156	MHHES1	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.039849995659906656	[623]	[791,698,661,599]	0	hSpCas9	negative selection	7419257
178623255	178623278	5	-	27260156	MHHES1	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.35143156940034903	[536]	[1049,902,747,482]	6	hSpCas9	negative selection	7419258
178616885	178616908	5	-	27260156	MHHES1	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.5601837138764088	[240]	[152,170,293,123]	-8	hSpCas9	negative selection	7419259
178618709	178618732	5	-	27260156	MEWO	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.5195355504611855	[410]	[342,295,179]	-8	hSpCas9	negative selection	7476235
178618736	178618759	5	-	27260156	MEWO	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.09781074459406436	[911]	[917,913,907]	2	hSpCas9	negative selection	7476236
178623343	178623366	5	-	27260156	MEWO	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.35572409573637936	[617]	[900,659,689]	7	hSpCas9	negative selection	7476237
178616937	178616960	5	-	27260156	MEWO	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.22703405196500356	[623]	[523,524,451]	-5	hSpCas9	negative selection	7540508
178623255	178623278	5	-	27260156	MEWO	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.4954676752979418	[536]	[675,788,652]	8	hSpCas9	negative selection	7540509
178616885	178616908	5	-	27260156	MEWO	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.40711872739138877	[240]	[245,124,153]	-7	hSpCas9	negative selection	7540510
178618709	178618732	5	-	27260156	LNCAPCLONEFGC	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.3372843686375254	[410]	[221,308,435,232]	-5	hSpCas9	negative selection	7597486
178618736	178618759	5	-	27260156	LNCAPCLONEFGC	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.43695239954939913	[911]	[1002,968,1226,1301]	7	hSpCas9	negative selection	7597487
178623343	178623366	5	-	27260156	LNCAPCLONEFGC	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.31740692483765903	[617]	[738,717,766,573]	5	hSpCas9	negative selection	7597488
178616937	178616960	5	-	27260156	LNCAPCLONEFGC	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.24089481401505877	[623]	[361,496,612,461]	-4	hSpCas9	negative selection	7661759
178623255	178623278	5	-	27260156	LNCAPCLONEFGC	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.5530218653270627	[536]	[623,895,713,609]	8	hSpCas9	negative selection	7661760
178616885	178616908	5	-	27260156	LNCAPCLONEFGC	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.206646755504849	[240]	[199,85,261,225]	-3	hSpCas9	negative selection	7661761
178618709	178618732	5	-	27260156	PANC0327	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.02209080893863083	[410]	[339,440,267,421]	0	hSpCas9	negative selection	7718737
178618736	178618759	5	-	27260156	PANC0327	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.3635503183697253	[911]	[1047,948,1303,880]	5	hSpCas9	negative selection	7718738
178623343	178623366	5	-	27260156	PANC0327	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.08840330879804026	[617]	[707,571,475,589]	1	hSpCas9	negative selection	7718739
178616937	178616960	5	-	27260156	PANC0327	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.5033163416028792	[623]	[373,364,379,446]	-6	hSpCas9	negative selection	7783010
178623255	178623278	5	-	27260156	PANC0327	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.6411399893113032	[536]	[957,681,665,694]	8	hSpCas9	negative selection	7783011
178616885	178616908	5	-	27260156	PANC0327	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	0.3333712000326068	[240]	[195,222,370,288]	5	hSpCas9	negative selection	7783012
178618709	178618732	5	-	27260156	NCIH2009	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.1778818934873226	[410]	[814,383,385]	-2	hSpCas9	negative selection	7839988
178618736	178618759	5	-	27260156	NCIH2009	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.5981084965786803	[911]	[2184,1420,2236]	7	hSpCas9	negative selection	7839989
178623343	178623366	5	-	27260156	NCIH2009	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.09842659899889633	[617]	[1031,734,696]	-1	hSpCas9	negative selection	7839990
178616937	178616960	5	-	27260156	NCIH2009	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.09707714676462104	[623]	[848,957,640]	-1	hSpCas9	negative selection	7904261
178623255	178623278	5	-	27260156	NCIH2009	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.40865011495225	[536]	[932,648,1397]	5	hSpCas9	negative selection	7904262
178616885	178616908	5	-	27260156	NCIH2009	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.39037664857823096	[240]	[286,211,277]	-5	hSpCas9	negative selection	7904263
178618709	178618732	5	-	27260156	NCIH1373	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.1519534549258306	[410]	[266,464,286,163]	-1	hSpCas9	negative selection	7961239
178618736	178618759	5	-	27260156	NCIH1373	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.6581508831514093	[911]	[2212,1423,1544,357]	6	hSpCas9	negative selection	7961240
178623343	178623366	5	-	27260156	NCIH1373	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.18878573043119246	[617]	[400,528,459,472]	1	hSpCas9	negative selection	7961241
178616937	178616960	5	-	27260156	NCIH1373	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.18227484474013164	[623]	[413,693,716,155]	-2	hSpCas9	negative selection	8025512
178623255	178623278	5	-	27260156	NCIH1373	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.8363543296617285	[536]	[891,1081,1209,282]	8	hSpCas9	negative selection	8025513
178616885	178616908	5	-	27260156	NCIH1373	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.643558822521507	[240]	[149,130,272,34]	-6	hSpCas9	negative selection	8025514
178618709	178618732	5	-	27260156	PATU8902	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.79709689708963	[410]	[449,366,362,96]	-6	hSpCas9	negative selection	8082490
178618736	178618759	5	-	27260156	PATU8902	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.5003342344489896	[911]	[1951,1701,1474,2168]	5	hSpCas9	negative selection	8082491
178623343	178623366	5	-	27260156	PATU8902	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.21976105915708294	[617]	[1245,855,852,1091]	2	hSpCas9	negative selection	8082492
178616937	178616960	5	-	27260156	PATU8902	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	0.12121218230387104	[623]	[1098,1205,616,933]	1	hSpCas9	negative selection	8146763
178623255	178623278	5	-	27260156	PATU8902	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.28510191804805757	[536]	[1266,804,913,609]	3	hSpCas9	negative selection	8146764
178616885	178616908	5	-	27260156	PATU8902	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-1.1988560473948777	[240]	[204,114,198,36]	-8	hSpCas9	negative selection	8146765
178618709	178618732	5	-	27260156	PANC1	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.17150298677070122	[410]	[236,412,157,439]	-3	hSpCas9	negative selection	8203741
178618736	178618759	5	-	27260156	PANC1	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.38532979539689727	[911]	[1061,1094,932,1001]	6	hSpCas9	negative selection	8203742
178623343	178623366	5	-	27260156	PANC1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.09673365369232678	[617]	[360,751,835,386]	1	hSpCas9	negative selection	8203743
178616937	178616960	5	-	27260156	PANC1	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.32351016068218447	[623]	[507,553,340,340]	-5	hSpCas9	negative selection	8268014
178623255	178623278	5	-	27260156	PANC1	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.4652327593477883	[536]	[591,675,611,660]	7	hSpCas9	negative selection	8268015
178616885	178616908	5	-	27260156	PANC1	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.2503501815836606	[240]	[129,219,201,154]	-4	hSpCas9	negative selection	8268016
178618709	178618732	5	-	27260156	PANC0813	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.3239624407274133	[410]	[483,268,354,439]	-5	hSpCas9	negative selection	8324992
178618736	178618759	5	-	27260156	PANC0813	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.44173243054964506	[911]	[1547,1675,1373,1239]	7	hSpCas9	negative selection	8324993
178623343	178623366	5	-	27260156	PANC0813	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.07518480812380984	[617]	[834,680,682,575]	-1	hSpCas9	negative selection	8324994
178616937	178616960	5	-	27260156	PANC0813	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.1716680837312837	[623]	[730,535,612,724]	-3	hSpCas9	negative selection	8389265
178623255	178623278	5	-	27260156	PANC0813	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.40377776740500504	[536]	[850,921,616,940]	6	hSpCas9	negative selection	8389266
178616885	178616908	5	-	27260156	PANC0813	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.2565026482612247	[240]	[231,330,136,245]	-4	hSpCas9	negative selection	8389267
178618709	178618732	5	-	27260156	RDES	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.061155148851879365	[410]	[392,443,481,500]	-1	hSpCas9	negative selection	8446243
178618736	178618759	5	-	27260156	RDES	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.5327564050131284	[911]	[1066,1357,1724,2084]	8	hSpCas9	negative selection	8446244
178623343	178623366	5	-	27260156	RDES	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.34077754743081873	[617]	[735,907,1006,970]	5	hSpCas9	negative selection	8446245
178616937	178616960	5	-	27260156	RDES	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.2992444656559523	[623]	[486,532,746,578]	-5	hSpCas9	negative selection	8510516
178623255	178623278	5	-	27260156	RDES	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.47440636181566365	[536]	[676,857,918,1017]	7	hSpCas9	negative selection	8510517
178616885	178616908	5	-	27260156	RDES	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.11227144927683153	[240]	[164,342,307,207]	-2	hSpCas9	negative selection	8510518
178618709	178618732	5	-	27260156	PC3	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.31049834296476464	[410]	[205,342,358,450]	-6	hSpCas9	negative selection	8567494
178618736	178618759	5	-	27260156	PC3	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.23455201843976203	[911]	[497,1098,1815,1335]	5	hSpCas9	negative selection	8567495
178623343	178623366	5	-	27260156	PC3	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.3328348445944818	[617]	[611,731,1140,739]	7	hSpCas9	negative selection	8567496
178616937	178616960	5	-	27260156	PC3	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.277794837534281	[623]	[390,567,751,419]	-6	hSpCas9	negative selection	8631767
178623255	178623278	5	-	27260156	PC3	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.6502511381411734	[536]	[553,937,1215,830]	9	hSpCas9	negative selection	8631768
178616885	178616908	5	-	27260156	PC3	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.32949864857537814	[240]	[143,240,211,169]	-6	hSpCas9	negative selection	8631769
178618709	178618732	5	-	27260156	PATU8988T	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.19100767003950173	[410]	[482,353,495,471]	3	hSpCas9	negative selection	8688745
178618736	178618759	5	-	27260156	PATU8988T	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.4050006770465002	[911]	[920,1674,942,1179]	7	hSpCas9	negative selection	8688746
178623343	178623366	5	-	27260156	PATU8988T	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.0407453974906396	[617]	[459,632,718,647]	0	hSpCas9	negative selection	8688747
178616937	178616960	5	-	27260156	PATU8988T	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.10497589087996351	[623]	[706,679,369,493]	-2	hSpCas9	negative selection	8753018
178623255	178623278	5	-	27260156	PATU8988T	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.33817750435630634	[536]	[616,816,445,770]	6	hSpCas9	negative selection	8753019
178616885	178616908	5	-	27260156	PATU8988T	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.5479536583509348	[240]	[156,98,143,237]	-7	hSpCas9	negative selection	8753020
178618709	178618732	5	-	27260156	T47D	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.10018395825508067	[410]	[411,537,525,575]	2	hSpCas9	negative selection	8809996
178618736	178618759	5	-	27260156	T47D	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.2864038298770111	[911]	[1219,1284,1440,1232]	6	hSpCas9	negative selection	8809997
178623343	178623366	5	-	27260156	T47D	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.19217703591769658	[617]	[854,778,828,830]	4	hSpCas9	negative selection	8809998
178616937	178616960	5	-	27260156	T47D	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.15210524212347282	[623]	[683,573,747,614]	-3	hSpCas9	negative selection	8874269
178623255	178623278	5	-	27260156	T47D	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.3769198421368758	[536]	[913,801,722,812]	7	hSpCas9	negative selection	8874270
178616885	178616908	5	-	27260156	T47D	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.27751153404826345	[240]	[195,256,197,274]	-6	hSpCas9	negative selection	8874271
178618709	178618732	5	-	27260156	SU8686	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.2652742427296252	[410]	[428,221,371,335]	-4	hSpCas9	negative selection	8931247
178618736	178618759	5	-	27260156	SU8686	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.5196654287759703	[911]	[1399,1171,1311,1295]	8	hSpCas9	negative selection	8931248
178623343	178623366	5	-	27260156	SU8686	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.34851059403079493	[617]	[801,555,914,889]	6	hSpCas9	negative selection	8931249
178616937	178616960	5	-	27260156	SU8686	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.2031875112910727	[623]	[454,575,539,586]	-4	hSpCas9	negative selection	8995520
178623255	178623278	5	-	27260156	SU8686	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.2455602333899875	[536]	[422,725,722,667]	4	hSpCas9	negative selection	8995521
178616885	178616908	5	-	27260156	SU8686	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.39746587716269377	[240]	[159,166,156,255]	-6	hSpCas9	negative selection	8995522
178618709	178618732	5	-	27260156	SKES1	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.39821893694544086	[410]	[368,356,292,243]	-7	hSpCas9	negative selection	9052498
178618736	178618759	5	-	27260156	SKES1	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.14032994449325153	[911]	[1232,1022,929,865]	3	hSpCas9	negative selection	9052499
178623343	178623366	5	-	27260156	SKES1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.11476117771754463	[617]	[780,670,700,540]	2	hSpCas9	negative selection	9052500
178616937	178616960	5	-	27260156	SKES1	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.32240185243348285	[623]	[573,454,508,457]	-6	hSpCas9	negative selection	9116771
178623255	178623278	5	-	27260156	SKES1	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.5363880558201064	[536]	[816,988,659,677]	9	hSpCas9	negative selection	9116772
178616885	178616908	5	-	27260156	SKES1	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.03345030245110381	[240]	[436,220,138,174]	0	hSpCas9	negative selection	9116773
178618709	178618732	5	-	27260156	TOV112D	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.041939706807265054	[410]	[414,341,582,249]	-1	hSpCas9	negative selection	9173749
178618736	178618759	5	-	27260156	TOV112D	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.3099943607475961	[911]	[845,1520,1204,1029]	6	hSpCas9	negative selection	9173750
178623343	178623366	5	-	27260156	TOV112D	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.3559061164452771	[617]	[840,1025,645,717]	6	hSpCas9	negative selection	9173751
178616937	178616960	5	-	27260156	TOV112D	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.2716099097316238	[623]	[419,747,560,392]	-5	hSpCas9	negative selection	9238022
178623255	178623278	5	-	27260156	TOV112D	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.47884662248353316	[536]	[954,533,788,684]	8	hSpCas9	negative selection	9238023
178616885	178616908	5	-	27260156	TOV112D	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	0.4957776952816131	[240]	[151,185,736,234]	8	hSpCas9	negative selection	9238024
178618709	178618732	5	-	27260156	TC71	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	-0.47270274905999476	[410]	[281,223,378,387]	-8	hSpCas9	negative selection	9295000
178618736	178618759	5	-	27260156	TC71	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.23539540222319033	[911]	[1160,1151,1114,1177]	6	hSpCas9	negative selection	9295001
178623343	178623366	5	-	27260156	TC71	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.23987630347236716	[617]	[590,815,811,921]	6	hSpCas9	negative selection	9295002
178616937	178616960	5	-	27260156	TC71	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.14114409330652256	[623]	[637,516,538,741]	-4	hSpCas9	negative selection	9359273
178623255	178623278	5	-	27260156	TC71	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.4323658895032205	[536]	[833,695,808,764]	8	hSpCas9	negative selection	9359274
178616885	178616908	5	-	27260156	TC71	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	-0.19640644575021105	[240]	[237,205,234,221]	-5	hSpCas9	negative selection	9359275
178618709	178618732	5	-	27260156	TC32	viability	GGAGATACGTTGACGAATACAGG	CLK4	ENSG00000113240	0.002012997016703072	[410]	[318,396,444,374]	0	hSpCas9	negative selection	9416251
178618736	178618759	5	-	27260156	TC32	viability	CCTTGAATGAGCGAGATTATCGG	CLK4	ENSG00000113240	0.20595158052869333	[911]	[871,925,1166,995]	4	hSpCas9	negative selection	9416252
178623343	178623366	5	-	27260156	TC32	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.1346060269685499	[617]	[483,553,783,773]	2	hSpCas9	negative selection	9416253
178616937	178616960	5	-	27260156	TC32	viability	CCTCACTCTAGATGAAATCGTGG	CLK4	ENSG00000113240	-0.19245280467595327	[623]	[437,375,594,699]	-3	hSpCas9	negative selection	9480524
178623255	178623278	5	-	27260156	TC32	viability	ACCAGTTTAAAGAATCTGATTGG	CLK4	ENSG00000113240	0.23715440339042676	[536]	[476,320,945,794]	4	hSpCas9	negative selection	9480525
178616885	178616908	5	-	27260156	TC32	viability	GTTGTAGAGTGCATTGATCATGG	CLK4	ENSG00000113240	0.01906874495300348	[240]	[289,186,239,193]	0	hSpCas9	negative selection	9480526
178612425	178612448	5	-	27869803	HPAFII	viability after 27 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-1.4584135688676032	[832]	[100,207,NaN]	-7	hSpCas9	negative selection	9591447
178618730	178618753	5	-	27869803	HPAFII	viability after 27 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.8173133367898133	[187]	[90,26,NaN]	-5	hSpCas9	negative selection	9591448
178623330	178623353	5	-	27869803	HPAFII	viability after 27 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.5993277546884661	[238]	[251,138,NaN]	5	hSpCas9	negative selection	9591449
178623363	178623386	5	-	27869803	HPAFII	viability after 27 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	-0.020537753926101354	[143]	[120,35,NaN]	0	hSpCas9	negative selection	9591450
178612425	178612448	5	-	27869803	HPAFII	viability after 15 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.979688314798888	[832]	[506,420,NaN]	-7	hSpCas9	negative selection	9673896
178618730	178618753	5	-	27869803	HPAFII	viability after 15 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-1.201334547624595	[187]	[77,93,NaN]	-8	hSpCas9	negative selection	9673897
178623330	178623353	5	-	27869803	HPAFII	viability after 15 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.6476682065621847	[238]	[468,360,NaN]	7	hSpCas9	negative selection	9673898
178623363	178623386	5	-	27869803	HPAFII	viability after 15 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.02639263314747231	[143]	[349,37,NaN]	0	hSpCas9	negative selection	9673899
178612425	178612448	5	-	27869803	ASPC1	viability after 36 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.6027196532353325	[1605]	[663,350,1370]	6	hSpCas9	negative selection	9756345
178618730	178618753	5	-	27869803	ASPC1	viability after 36 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.7395287057871522	[418]	[190,83,16]	-6	hSpCas9	negative selection	9756346
178623330	178623353	5	-	27869803	ASPC1	viability after 36 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.14527697634765352	[524]	[102,133,324]	1	hSpCas9	negative selection	9756347
178623363	178623386	5	-	27869803	ASPC1	viability after 36 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.9624650596201895	[301]	[229,47,310]	8	hSpCas9	negative selection	9756348
178612425	178612448	5	-	27869803	PATU8988S	viability after 35 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.16421058709828862	[1325]	[516,435,NaN]	-2	hSpCas9	negative selection	9838794
178618730	178618753	5	-	27869803	PATU8988S	viability after 35 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.23014009769382215	[284]	[193,74,NaN]	2	hSpCas9	negative selection	9838795
178623330	178623353	5	-	27869803	PATU8988S	viability after 35 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.3219021764540836	[503]	[114,209,NaN]	-3	hSpCas9	negative selection	9838796
178623363	178623386	5	-	27869803	PATU8988S	viability after 35 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.5605744702799286	[242]	[74,213,NaN]	6	hSpCas9	negative selection	9838797
178612425	178612448	5	-	27869803	PATU8988S	viability after 31 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.42653141612757817	[1325]	[216,617,NaN]	-5	hSpCas9	negative selection	9921243
178618730	178618753	5	-	27869803	PATU8988S	viability after 31 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	0.31003989106906726	[284]	[172,99,NaN]	4	hSpCas9	negative selection	9921244
178623330	178623353	5	-	27869803	PATU8988S	viability after 31 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	-0.17548369023213015	[503]	[129,238,NaN]	-2	hSpCas9	negative selection	9921245
178623363	178623386	5	-	27869803	PATU8988S	viability after 31 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.3696095599276932	[242]	[67,197,NaN]	4	hSpCas9	negative selection	9921246
178612425	178612448	5	-	27869803	HPAFII	viability after 35 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-1.2352174663553046	[832]	[85,283,NaN]	-6	hSpCas9	negative selection	10003692
178618730	178618753	5	-	27869803	HPAFII	viability after 35 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.3649746906825584	[187]	[111,30,NaN]	-2	hSpCas9	negative selection	10003693
178623330	178623353	5	-	27869803	HPAFII	viability after 35 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.4702769955943897	[238]	[232,93,NaN]	3	hSpCas9	negative selection	10003694
178623363	178623386	5	-	27869803	HPAFII	viability after 35 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	1.1216713601066108	[143]	[239,66,NaN]	7	hSpCas9	negative selection	10003695
178612425	178612448	5	-	27869803	HPAFII	viability after 31 days	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-1.5884946792365882	[832]	[64,253,NaN]	-7	hSpCas9	negative selection	10086141
178618730	178618753	5	-	27869803	HPAFII	viability after 31 days	ATGAGCGAGATTATCGGGACCGG	CLK4	ENSG00000113240	-0.2179597924004555	[187]	[128,48,NaN]	-1	hSpCas9	negative selection	10086142
178623330	178623353	5	-	27869803	HPAFII	viability after 31 days	GCTATCGTGGAAGTCACAAGCGG	CLK4	ENSG00000113240	0.2661709054954421	[238]	[223,92,NaN]	2	hSpCas9	negative selection	10086143
178623363	178623386	5	-	27869803	HPAFII	viability after 31 days	ATTGGGATAGCAGAGAAAGCTGG	CLK4	ENSG00000113240	0.5149275533988819	[143]	[181,42,NaN]	4	hSpCas9	negative selection	10086144
178618621	178618644	5	+	28162770	P31FUJ	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.427612524736243	[297]	[470]	5	hSpCas9	negative selection	10134722
178623294	178623317	5	-	28162770	P31FUJ	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.2805373684762691	[233]	[333]	3	hSpCas9	negative selection	10134723
178623361	178623384	5	-	28162770	P31FUJ	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.02295896650723743	[231]	[276]	0	hSpCas9	negative selection	10134724
178623324	178623347	5	-	28162770	P31FUJ	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.8287730747065749	[343]	[717]	8	hSpCas9	negative selection	10134725
178617420	178617443	5	-	28162770	P31FUJ	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-0.36815405730926465	[133]	[121]	-3	hSpCas9	negative selection	10134726
178617398	178617421	5	-	28162770	P31FUJ	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	1.0361937596581319	[160]	[387]	9	hSpCas9	negative selection	10134727
178616896	178616919	5	+	28162770	P31FUJ	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.007596004976385351	[181]	[214]	0	hSpCas9	negative selection	10134728
178612425	178612448	5	-	28162770	P31FUJ	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.8603071999771028	[209]	[447]	8	hSpCas9	negative selection	10134729
178623343	178623366	5	-	28162770	P31FUJ	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.8529276696115053	[440]	[935]	8	hSpCas9	negative selection	10134730
178603843	178603866	5	-	28162770	P31FUJ	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.44561120739671445	[527]	[844]	5	hSpCas9	negative selection	10134731
178618621	178618644	5	+	28162770	TF1	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	NaN	[NaN]	[284]	1	hSpCas9	negative selection	10304088
178623294	178623317	5	-	28162770	TF1	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	NaN	[NaN]	[159]	1	hSpCas9	negative selection	10304089
178623361	178623384	5	-	28162770	TF1	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10304090
178623324	178623347	5	-	28162770	TF1	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10304091
178617420	178617443	5	-	28162770	TF1	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10304092
178617398	178617421	5	-	28162770	TF1	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	NaN	[NaN]	[354]	1	hSpCas9	negative selection	10304093
178616896	178616919	5	+	28162770	TF1	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10304094
178612425	178612448	5	-	28162770	TF1	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10304095
178623343	178623366	5	-	28162770	TF1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	NaN	[NaN]	[499]	1	hSpCas9	negative selection	10304096
178603843	178603866	5	-	28162770	TF1	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	NaN	[NaN]	[608]	1	hSpCas9	negative selection	10304097
178618621	178618644	5	+	28162770	SKM1	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.5268934444656261	[105]	[269]	5	hSpCas9	negative selection	10473454
178623294	178623317	5	-	28162770	SKM1	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.6044102629493788	[42]	[49]	-5	hSpCas9	negative selection	10473455
178623361	178623384	5	-	28162770	SKM1	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	-0.6029919160802096	[60]	[70]	-5	hSpCas9	negative selection	10473456
178623324	178623347	5	-	28162770	SKM1	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.5553653832907832	[96]	[251]	5	hSpCas9	negative selection	10473457
178617420	178617443	5	-	28162770	SKM1	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-1.4809647801869388	[29]	[18]	-7	hSpCas9	negative selection	10473458
178617398	178617421	5	-	28162770	SKM1	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.45671433004405815	[60]	[147]	4	hSpCas9	negative selection	10473459
178616896	178616919	5	+	28162770	SKM1	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	1.2654611432283338	[31]	[135]	9	hSpCas9	negative selection	10473460
178612425	178612448	5	-	28162770	SKM1	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.14392979290936794	[49]	[79]	-1	hSpCas9	negative selection	10473461
178623343	178623366	5	-	28162770	SKM1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.16175106999661215	[111]	[176]	-1	hSpCas9	negative selection	10473462
178603843	178603866	5	-	28162770	SKM1	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.14052359655933166	[155]	[303]	1	hSpCas9	negative selection	10473463
178618621	178618644	5	+	28162770	SKM1	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.5268934444656261	[105]	[269]	5	hSpCas9	negative selection	10642820
178623294	178623317	5	-	28162770	SKM1	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.6044102629493788	[42]	[49]	-5	hSpCas9	negative selection	10642821
178623361	178623384	5	-	28162770	SKM1	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	-0.6029919160802096	[60]	[70]	-5	hSpCas9	negative selection	10642822
178623324	178623347	5	-	28162770	SKM1	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.5553653832907832	[96]	[251]	5	hSpCas9	negative selection	10642823
178617420	178617443	5	-	28162770	SKM1	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-1.4809647801869388	[29]	[18]	-7	hSpCas9	negative selection	10642824
178617398	178617421	5	-	28162770	SKM1	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.45671433004405815	[60]	[147]	4	hSpCas9	negative selection	10642825
178616896	178616919	5	+	28162770	SKM1	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	1.2654611432283338	[31]	[135]	9	hSpCas9	negative selection	10642826
178612425	178612448	5	-	28162770	SKM1	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.14392979290936794	[49]	[79]	-1	hSpCas9	negative selection	10642827
178623343	178623366	5	-	28162770	SKM1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.16175106999661215	[111]	[176]	-1	hSpCas9	negative selection	10642828
178603843	178603866	5	-	28162770	SKM1	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.14052359655933166	[155]	[303]	1	hSpCas9	negative selection	10642829
178618621	178618644	5	+	28162770	PL21	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	-0.12924428531708965	[484]	[192]	-1	hSpCas9	negative selection	10812186
178623294	178623317	5	-	28162770	PL21	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.04378596839676907	[134]	[56]	0	hSpCas9	negative selection	10812187
178623361	178623384	5	-	28162770	PL21	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	-0.054674284539505305	[209]	[87]	0	hSpCas9	negative selection	10812188
178623324	178623347	5	-	28162770	PL21	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.9297256782899286	[391]	[324]	7	hSpCas9	negative selection	10812189
178617420	178617443	5	-	28162770	PL21	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	0.04581146809802639	[137]	[61]	0	hSpCas9	negative selection	10812190
178617398	178617421	5	-	28162770	PL21	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	-0.5295944104458102	[198]	[59]	-4	hSpCas9	negative selection	10812191
178616896	178616919	5	+	28162770	PL21	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	1.2133150032370534	[108]	[109]	8	hSpCas9	negative selection	10812192
178612425	178612448	5	-	28162770	PL21	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.19272214292683693	[194]	[96]	1	hSpCas9	negative selection	10812193
178623343	178623366	5	-	28162770	PL21	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.26229241086040056	[360]	[130]	-2	hSpCas9	negative selection	10812194
178603843	178603866	5	-	28162770	PL21	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	1.0966350387354602	[389]	[362]	8	hSpCas9	negative selection	10812195
178618621	178618644	5	+	28162770	P31FUJ	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.427612524736243	[297]	[470]	5	hSpCas9	negative selection	10981552
178623294	178623317	5	-	28162770	P31FUJ	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.2805373684762691	[233]	[333]	3	hSpCas9	negative selection	10981553
178623361	178623384	5	-	28162770	P31FUJ	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.02295896650723743	[231]	[276]	0	hSpCas9	negative selection	10981554
178623324	178623347	5	-	28162770	P31FUJ	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.8287730747065749	[343]	[717]	8	hSpCas9	negative selection	10981555
178617420	178617443	5	-	28162770	P31FUJ	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-0.36815405730926465	[133]	[121]	-3	hSpCas9	negative selection	10981556
178617398	178617421	5	-	28162770	P31FUJ	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	1.0361937596581319	[160]	[387]	9	hSpCas9	negative selection	10981557
178616896	178616919	5	+	28162770	P31FUJ	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.007596004976385351	[181]	[214]	0	hSpCas9	negative selection	10981558
178612425	178612448	5	-	28162770	P31FUJ	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.8603071999771028	[209]	[447]	8	hSpCas9	negative selection	10981559
178623343	178623366	5	-	28162770	P31FUJ	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.8529276696115053	[440]	[935]	8	hSpCas9	negative selection	10981560
178603843	178603866	5	-	28162770	P31FUJ	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.44561120739671445	[527]	[844]	5	hSpCas9	negative selection	10981561
178618621	178618644	5	+	28162770	OCIAML5	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.40032059077028825	[169]	[404]	3	hSpCas9	negative selection	11150918
178623294	178623317	5	-	28162770	OCIAML5	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.015565303146876486	[153]	[274]	0	hSpCas9	negative selection	11150919
178623361	178623384	5	-	28162770	OCIAML5	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	-0.7849523750054602	[125]	[131]	-5	hSpCas9	negative selection	11150920
178623324	178623347	5	-	28162770	OCIAML5	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	-0.4042229265019116	[249]	[340]	-3	hSpCas9	negative selection	11150921
178617420	178617443	5	-	28162770	OCIAML5	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	1.254132832967928	[35]	[154]	9	hSpCas9	negative selection	11150922
178617398	178617421	5	-	28162770	OCIAML5	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	1.0758620145153086	[117]	[448]	8	hSpCas9	negative selection	11150923
178616896	178616919	5	+	28162770	OCIAML5	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.4745078888797302	[123]	[310]	4	hSpCas9	negative selection	11150924
178612425	178612448	5	-	28162770	OCIAML5	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	-0.490558468001948	[150]	[193]	-3	hSpCas9	negative selection	11150925
178623343	178623366	5	-	28162770	OCIAML5	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.6451670804856846	[225]	[637]	5	hSpCas9	negative selection	11150926
178603843	178603866	5	-	28162770	OCIAML5	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	-0.19377529082570333	[357]	[564]	-1	hSpCas9	negative selection	11150927
178618621	178618644	5	+	28162770	EOL1	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	1.0395134856910548	[650]	[704]	8	hSpCas9	negative selection	11320284
178623294	178623317	5	-	28162770	EOL1	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.49330474331536334	[170]	[63]	-4	hSpCas9	negative selection	11320285
178623361	178623384	5	-	28162770	EOL1	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	-0.8136609894463038	[386]	[115]	-5	hSpCas9	negative selection	11320286
178623324	178623347	5	-	28162770	EOL1	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.11667897772089408	[701]	[400]	1	hSpCas9	negative selection	11320287
178617420	178617443	5	-	28162770	EOL1	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-0.7723076092215186	[200]	[61]	-5	hSpCas9	negative selection	11320288
178617398	178617421	5	-	28162770	EOL1	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.6573255687733071	[413]	[343]	6	hSpCas9	negative selection	11320289
178616896	178616919	5	+	28162770	EOL1	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.407870010415853	[195]	[136]	4	hSpCas9	negative selection	11320290
178612425	178612448	5	-	28162770	EOL1	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.8241458746126971	[237]	[221]	7	hSpCas9	negative selection	11320291
178623343	178623366	5	-	28162770	EOL1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.48055889859556167	[452]	[332]	4	hSpCas9	negative selection	11320292
178603843	178603866	5	-	28162770	EOL1	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	-0.4714927372509432	[678]	[257]	-3	hSpCas9	negative selection	11320293
178618621	178618644	5	+	28162770	MOLM13	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.8395296889173931	[598]	[774]	6	hSpCas9	negative selection	11489650
178623294	178623317	5	-	28162770	MOLM13	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.2858275769109521	[230]	[136]	-2	hSpCas9	negative selection	11489651
178623361	178623384	5	-	28162770	MOLM13	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.7778808566642424	[266]	[330]	6	hSpCas9	negative selection	11489652
178623324	178623347	5	-	28162770	MOLM13	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.13359629254096317	[497]	[394]	0	hSpCas9	negative selection	11489653
178617420	178617443	5	-	28162770	MOLM13	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-1.2363720475489217	[188]	[57]	-6	hSpCas9	negative selection	11489654
178617398	178617421	5	-	28162770	MOLM13	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.2528051247880104	[360]	[310]	1	hSpCas9	negative selection	11489655
178616896	178616919	5	+	28162770	MOLM13	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.2986525246614087	[261]	[232]	2	hSpCas9	negative selection	11489656
178612425	178612448	5	-	28162770	MOLM13	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.06879342613475661	[239]	[181]	0	hSpCas9	negative selection	11489657
178623343	178623366	5	-	28162770	MOLM13	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.1282879066725039	[451]	[298]	-1	hSpCas9	negative selection	11489658
178603843	178603866	5	-	28162770	MOLM13	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	-0.19603646707143385	[750]	[473]	-1	hSpCas9	negative selection	11489659
178618621	178618644	5	+	28162770	HEL	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.4313939031780639	[476]	[411]	3	hSpCas9	negative selection	11659016
178623294	178623317	5	-	28162770	HEL	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.20670149142426175	[199]	[110]	-1	hSpCas9	negative selection	11659017
178623361	178623384	5	-	28162770	HEL	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.2891018773856564	[252]	[197]	2	hSpCas9	negative selection	11659018
178623324	178623347	5	-	28162770	HEL	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	1.0503050818480655	[483]	[641]	8	hSpCas9	negative selection	11659019
178617420	178617443	5	-	28162770	HEL	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	0.29791033500291564	[126]	[99]	2	hSpCas9	negative selection	11659020
178617398	178617421	5	-	28162770	HEL	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.6971866160227334	[259]	[269]	6	hSpCas9	negative selection	11659021
178616896	178616919	5	+	28162770	HEL	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.018496343617389496	[241]	[156]	0	hSpCas9	negative selection	11659022
178612425	178612448	5	-	28162770	HEL	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.6503120517051576	[189]	[190]	5	hSpCas9	negative selection	11659023
178623343	178623366	5	-	28162770	HEL	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.9714401554831457	[339]	[426]	8	hSpCas9	negative selection	11659024
178603843	178603866	5	-	28162770	HEL	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.49434699210768596	[531]	[479]	4	hSpCas9	negative selection	11659025
178618621	178618644	5	+	28162770	MV411	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.09543445733772538	[359]	[323]	0	hSpCas9	negative selection	11828382
178623294	178623317	5	-	28162770	MV411	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.35742450737608567	[145]	[95]	-3	hSpCas9	negative selection	11828383
178623361	178623384	5	-	28162770	MV411	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.8791311018489225	[161]	[250]	7	hSpCas9	negative selection	11828384
178623324	178623347	5	-	28162770	MV411	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.4395582983392837	[343]	[392]	4	hSpCas9	negative selection	11828385
178617420	178617443	5	-	28162770	MV411	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	0.6980989597923406	[119]	[163]	6	hSpCas9	negative selection	11828386
178617398	178617421	5	-	28162770	MV411	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	1.1191134538072358	[187]	[343]	8	hSpCas9	negative selection	11828387
178616896	178616919	5	+	28162770	MV411	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.6489539104080002	[133]	[176]	6	hSpCas9	negative selection	11828388
178612425	178612448	5	-	28162770	MV411	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.13612052791861734	[201]	[186]	1	hSpCas9	negative selection	11828389
178623343	178623366	5	-	28162770	MV411	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	-0.10756236571023581	[352]	[275]	-1	hSpCas9	negative selection	11828390
178603843	178603866	5	-	28162770	MV411	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.13002438650160464	[434]	[400]	1	hSpCas9	negative selection	11828391
178618621	178618644	5	+	28162770	MONOMAC1	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.46736012115600745	[264]	[419]	4	hSpCas9	negative selection	11997748
178623294	178623317	5	-	28162770	MONOMAC1	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	-0.1656726761502187	[90]	[92]	-1	hSpCas9	negative selection	11997749
178623361	178623384	5	-	28162770	MONOMAC1	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	1.0483741908796238	[150]	[357]	8	hSpCas9	negative selection	11997750
178623324	178623347	5	-	28162770	MONOMAC1	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.5079070740561267	[245]	[400]	5	hSpCas9	negative selection	11997751
178617420	178617443	5	-	28162770	MONOMAC1	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-1.0715059649756948	[76]	[41]	-7	hSpCas9	negative selection	11997752
178617398	178617421	5	-	28162770	MONOMAC1	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.3498576128280828	[127]	[186]	3	hSpCas9	negative selection	11997753
178616896	178616919	5	+	28162770	MONOMAC1	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	1.7278616976997274	[68]	[261]	9	hSpCas9	negative selection	11997754
178612425	178612448	5	-	28162770	MONOMAC1	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.1331117546327772	[104]	[131]	1	hSpCas9	negative selection	11997755
178623343	178623366	5	-	28162770	MONOMAC1	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	2.0014573065795296	[199]	[917]	9	hSpCas9	negative selection	11997756
178603843	178603866	5	-	28162770	MONOMAC1	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	-0.32434117133463203	[295]	[270]	-3	hSpCas9	negative selection	11997757
178618621	178618644	5	+	28162770	OCIAML2	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	-0.5019939961514963	[92]	[363]	-4	hSpCas9	negative selection	12167114
178623294	178623317	5	-	28162770	OCIAML2	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.5964843706163758	[20]	[175]	6	hSpCas9	negative selection	12167115
178623361	178623384	5	-	28162770	OCIAML2	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.25285253956042275	[42]	[283]	2	hSpCas9	negative selection	12167116
178623324	178623347	5	-	28162770	OCIAML2	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	0.3644458543738929	[80]	[577]	3	hSpCas9	negative selection	12167117
178617420	178617443	5	-	28162770	OCIAML2	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	-0.17995266433923862	[27]	[136]	-1	hSpCas9	negative selection	12167118
178617398	178617421	5	-	28162770	OCIAML2	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	0.8676000819743015	[43]	[444]	8	hSpCas9	negative selection	12167119
178616896	178616919	5	+	28162770	OCIAML2	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	-0.0011445419409410462	[25]	[143]	0	hSpCas9	negative selection	12167120
178612425	178612448	5	-	28162770	OCIAML2	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.34335818914788996	[30]	[217]	3	hSpCas9	negative selection	12167121
178623343	178623366	5	-	28162770	OCIAML2	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.005103605724236515	[63]	[355]	0	hSpCas9	negative selection	12167122
178603843	178603866	5	-	28162770	OCIAML2	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.25291525316172314	[80]	[534]	2	hSpCas9	negative selection	12167123
178618621	178618644	5	+	28162770	OCIAML3	viability	GGACTGAAGATTTACTGCAGTGG	CLK4	ENSG00000113240	0.024121724332192174	[85]	[263]	0	hSpCas9	negative selection	12336480
178623294	178623317	5	-	28162770	OCIAML3	viability	ATAGTAGCACACAAGAGAACAGG	CLK4	ENSG00000113240	0.35919814819689566	[46]	[181]	3	hSpCas9	negative selection	12336481
178623361	178623384	5	-	28162770	OCIAML3	viability	TGGGATAGCAGAGAAAGCTGGGG	CLK4	ENSG00000113240	0.6420597179093612	[44]	[211]	6	hSpCas9	negative selection	12336482
178623324	178623347	5	-	28162770	OCIAML3	viability	GTGGAAGTCACAAGCGGAAGAGG	CLK4	ENSG00000113240	1.1876758741312439	[80]	[556]	8	hSpCas9	negative selection	12336483
178617420	178617443	5	-	28162770	OCIAML3	viability	CGTTCCAGAAGAGCCACCGAAGG	CLK4	ENSG00000113240	1.3570827591948904	[14]	[115]	9	hSpCas9	negative selection	12336484
178617398	178617421	5	-	28162770	OCIAML3	viability	GAAAAGATCCAGGAGTATAGAGG	CLK4	ENSG00000113240	-0.08059840062804094	[61]	[176]	0	hSpCas9	negative selection	12336485
178616896	178616919	5	+	28162770	OCIAML3	viability	GCACTCTACAACTTTGCCAAAGG	CLK4	ENSG00000113240	0.7937225129589454	[29]	[156]	7	hSpCas9	negative selection	12336486
178612425	178612448	5	-	28162770	OCIAML3	viability	CCGGCACTACAGAGCTCCCGAGG	CLK4	ENSG00000113240	0.9213493929111263	[45]	[262]	7	hSpCas9	negative selection	12336487
178623343	178623366	5	-	28162770	OCIAML3	viability	TGGGGACATGAAAGCTATCGTGG	CLK4	ENSG00000113240	0.952065847003398	[93]	[548]	8	hSpCas9	negative selection	12336488
178603843	178603866	5	-	28162770	OCIAML3	viability	GAGACGCTGCAAACCGTTGAAGG	CLK4	ENSG00000113240	0.0707221371943314	[128]	[408]	0	hSpCas9	negative selection	12336489