Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:80781
• Symbol:COL18A1
• Description:collagen type XVIII alpha 1 chain

DataSource: http://genomecrispr.dkfz.de/#!/results/COL18A1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45490842	45490865	21	+	26472758	Jiyoye	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.539625677529523	[103]	[113]	4	hSpCas9	negative selection	35033
45468312	45468335	21	+	26472758	Jiyoye	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.444169588988075	[76]	[78]	3	hSpCas9	negative selection	35034
45468389	45468412	21	-	26472758	Jiyoye	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.3557854211932774	[55]	[32]	-3	hSpCas9	negative selection	35035
45468621	45468644	21	+	26472758	Jiyoye	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.16751878376145557	[279]	[187]	-1	hSpCas9	negative selection	35036
45475514	45475537	21	+	26472758	Jiyoye	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.5254953486946347	[116]	[126]	4	hSpCas9	negative selection	35037
45476446	45476469	21	+	26472758	Jiyoye	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	4.577100382948185	[0]	[17]	9	hSpCas9	negative selection	35038
45477936	45477959	21	+	26472758	Jiyoye	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	0.20435849850618637	[60]	[52]	1	hSpCas9	negative selection	35039
45480498	45480521	21	+	26472758	Jiyoye	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	0.23029761942179405	[25]	[22]	1	hSpCas9	negative selection	35040
45480837	45480860	21	-	26472758	Jiyoye	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.7856870047596032	[109]	[142]	5	hSpCas9	negative selection	35041
45490842	45490865	21	+	26472758	KBM7	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.41633363622432146	[624,447]	[207,443]	4	hSpCas9	negative selection	226151
45468312	45468335	21	+	26472758	KBM7	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.6264884036937991	[442,238]	[275,209]	7	hSpCas9	negative selection	226152
45468389	45468412	21	-	26472758	KBM7	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.172220204905718	[300,262]	[146,90]	-2	hSpCas9	negative selection	226153
45468621	45468644	21	+	26472758	KBM7	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.10678343283722092	[685,802]	[342,316]	-1	hSpCas9	negative selection	226154
45475514	45475537	21	+	26472758	KBM7	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.9107888445965194	[409,316]	[418,228]	8	hSpCas9	negative selection	226155
45476446	45476469	21	+	26472758	KBM7	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	0.8473623041445919	[90,61]	[67,59]	8	hSpCas9	negative selection	226156
45477936	45477959	21	+	26472758	KBM7	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	1.116562958226649	[269,279]	[522,66]	9	hSpCas9	negative selection	226157
45480498	45480521	21	+	26472758	KBM7	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	0.972497081788517	[143,60]	[88,92]	9	hSpCas9	negative selection	226158
45480837	45480860	21	-	26472758	KBM7	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.4273631751245199	[363,244]	[158,216]	4	hSpCas9	negative selection	226159
45490842	45490865	21	+	26472758	Raji	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.1847256239067644	[344]	[90]	1	hSpCas9	negative selection	417269
45468312	45468335	21	+	26472758	Raji	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	-0.567776774319135	[197]	[30]	-4	hSpCas9	negative selection	417270
45468389	45468412	21	-	26472758	Raji	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.9650249601544504	[142]	[16]	-6	hSpCas9	negative selection	417271
45468621	45468644	21	+	26472758	Raji	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.4175982096971713	[370]	[114]	4	hSpCas9	negative selection	417272
45475514	45475537	21	+	26472758	Raji	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.02701011890957941	[202]	[47]	0	hSpCas9	negative selection	417273
45476446	45476469	21	+	26472758	Raji	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-0.3400754415976217	[59]	[10]	-3	hSpCas9	negative selection	417274
45477936	45477959	21	+	26472758	Raji	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.3726094057460141	[105]	[18]	-3	hSpCas9	negative selection	417275
45480498	45480521	21	+	26472758	Raji	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	1.446185448825358	[67]	[42]	9	hSpCas9	negative selection	417276
45480837	45480860	21	-	26472758	Raji	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.8284075856707841	[181]	[74]	7	hSpCas9	negative selection	417277
45490842	45490865	21	+	26472758	K562	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.7003186553334908	[408]	[560]	6	hSpCas9	negative selection	608387
45468312	45468335	21	+	26472758	K562	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.7421588162755403	[249]	[352]	6	hSpCas9	negative selection	608388
45468389	45468412	21	-	26472758	K562	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	1.0995450982795019	[156]	[283]	8	hSpCas9	negative selection	608389
45468621	45468644	21	+	26472758	K562	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.2585135575522336	[712]	[719]	2	hSpCas9	negative selection	608390
45475514	45475537	21	+	26472758	K562	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.3249842089701153	[295]	[312]	2	hSpCas9	negative selection	608391
45476446	45476469	21	+	26472758	K562	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	0.8558534397487945	[35]	[54]	7	hSpCas9	negative selection	608392
45477936	45477959	21	+	26472758	K562	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.9255062737758655	[269]	[119]	-5	hSpCas9	negative selection	608393
45480498	45480521	21	+	26472758	K562	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	0.49234624111003256	[79]	[94]	4	hSpCas9	negative selection	608394
45480837	45480860	21	-	26472758	K562	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.5231347557325103	[243]	[295]	4	hSpCas9	negative selection	608395
45405459	45405482	21	-	26627737	DLD1	viability	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.31552372695010256	[130]	[35,39,72]	3	hSpCas9	negative selection	816537
45455724	45455747	21	-	26627737	DLD1	viability	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	0.23717459540242414	[869]	[349,293,316]	2	hSpCas9	negative selection	816538
45468424	45468447	21	+	26627737	DLD1	viability	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	-0.10104121174342562	[1218]	[464,404,218]	-1	hSpCas9	negative selection	816539
45473903	45473926	21	+	26627737	DLD1	viability	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.5479128220884015	[416]	[265,127,176]	5	hSpCas9	negative selection	816540
45475477	45475500	21	+	26627737	DLD1	viability	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.9109092817766502	[254]	[158,144,145]	8	hSpCas9	negative selection	816541
45478333	45478356	21	-	26627737	DLD1	viability	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.8240582104727225	[296]	[110,181,195]	7	hSpCas9	negative selection	816542
45405459	45405482	21	-	26627737	GBM cells	viability after 5 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-1.1190080331115766	[80]	[24,14]	-9	hSpCas9	negative selection	898852
45455724	45455747	21	-	26627737	GBM cells	viability after 5 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.5616917801985176	[460]	[182,151]	-7	hSpCas9	negative selection	898853
45468424	45468447	21	+	26627737	GBM cells	viability after 5 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	-0.4176052341330583	[598]	[247,232]	-6	hSpCas9	negative selection	898854
45473903	45473926	21	+	26627737	GBM cells	viability after 5 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.8240266632546938	[256]	[213,273]	9	hSpCas9	negative selection	898855
45475477	45475500	21	+	26627737	GBM cells	viability after 5 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.17482957201621194	[222]	[170,98]	2	hSpCas9	negative selection	898856
45478333	45478356	21	-	26627737	GBM cells	viability after 5 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.40685395538299673	[108]	[94,59]	6	hSpCas9	negative selection	898857
45405459	45405482	21	-	26627737	GBM cells	viability after 13 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-0.9579009922229718	[80]	[31,14]	-8	hSpCas9	negative selection	981167
45455724	45455747	21	-	26627737	GBM cells	viability after 13 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.505521950155333	[460]	[141,203]	-5	hSpCas9	negative selection	981168
45468424	45468447	21	+	26627737	GBM cells	viability after 13 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.0028888921117740107	[598]	[248,387]	0	hSpCas9	negative selection	981169
45473903	45473926	21	+	26627737	GBM cells	viability after 13 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.6468509744984335	[256]	[262,181]	7	hSpCas9	negative selection	981170
45475477	45475500	21	+	26627737	GBM cells	viability after 13 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.03915877943859605	[222]	[152,100]	0	hSpCas9	negative selection	981171
45478333	45478356	21	-	26627737	GBM cells	viability after 13 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.12267695377460552	[108]	[86,45]	1	hSpCas9	negative selection	981172
45405459	45405482	21	-	26627737	GBM cells	viability after 21 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-2.3386013023076004	[80]	[3,12]	-9	hSpCas9	negative selection	1063482
45455724	45455747	21	-	26627737	GBM cells	viability after 21 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.3013175333363908	[460]	[220,186]	-3	hSpCas9	negative selection	1063483
45468424	45468447	21	+	26627737	GBM cells	viability after 21 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	-0.2629655249241458	[598]	[289,253]	-2	hSpCas9	negative selection	1063484
45473903	45473926	21	+	26627737	GBM cells	viability after 21 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	1.033414767559182	[256]	[278,291]	8	hSpCas9	negative selection	1063485
45475477	45475500	21	+	26627737	GBM cells	viability after 21 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.02588232616244915	[222]	[126,119]	0	hSpCas9	negative selection	1063486
45478333	45478356	21	-	26627737	GBM cells	viability after 21 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.40037892615946946	[108]	[47,41]	-4	hSpCas9	negative selection	1063487
45405459	45405482	21	-	26627737	RPE1	viability after 9 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	1.3009173737186008	[106]	[99,59]	7	hSpCas9	negative selection	1145797
45455724	45455747	21	-	26627737	RPE1	viability after 9 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	0.7148153127098149	[1059]	[345,800]	5	hSpCas9	negative selection	1145798
45468424	45468447	21	+	26627737	RPE1	viability after 9 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.2640193864820659	[904]	[296,395]	2	hSpCas9	negative selection	1145799
45473903	45473926	21	+	26627737	RPE1	viability after 9 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	1.0107651159650746	[766]	[499,462]	6	hSpCas9	negative selection	1145800
45475477	45475500	21	+	26627737	RPE1	viability after 9 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.7371407814951366	[391]	[204,203]	5	hSpCas9	negative selection	1145801
45478333	45478356	21	-	26627737	RPE1	viability after 9 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.14675595868988522	[448]	[59,278]	1	hSpCas9	negative selection	1145802
45405459	45405482	21	-	26627737	RPE1	viability after 12 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	1.7184127037240235	[106]	[114,72]	8	hSpCas9	negative selection	1228112
45455724	45455747	21	-	26627737	RPE1	viability after 12 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	0.5796172028364035	[1059]	[258,601]	4	hSpCas9	negative selection	1228113
45468424	45468447	21	+	26627737	RPE1	viability after 12 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.6772218384209887	[904]	[466,305]	4	hSpCas9	negative selection	1228114
45473903	45473926	21	+	26627737	RPE1	viability after 12 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.9948192260787828	[766]	[551,260]	6	hSpCas9	negative selection	1228115
45475477	45475500	21	+	26627737	RPE1	viability after 12 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	1.0635105384564225	[391]	[325,107]	6	hSpCas9	negative selection	1228116
45478333	45478356	21	-	26627737	RPE1	viability after 12 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.5360440895140162	[448]	[86,267]	3	hSpCas9	negative selection	1228117
45405459	45405482	21	-	26627737	RPE1	viability after 15 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	2.0745585219105243	[106]	[155,99]	8	hSpCas9	negative selection	1310427
45455724	45455747	21	-	26627737	RPE1	viability after 15 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	0.003088918914961103	[1059]	[103,489]	0	hSpCas9	negative selection	1310428
45468424	45468447	21	+	26627737	RPE1	viability after 15 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.806229246052217	[904]	[494,401]	5	hSpCas9	negative selection	1310429
45473903	45473926	21	+	26627737	RPE1	viability after 15 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.26615935223184717	[766]	[236,283]	1	hSpCas9	negative selection	1310430
45475477	45475500	21	+	26627737	RPE1	viability after 15 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.6085170666520021	[391]	[136,199]	4	hSpCas9	negative selection	1310431
45478333	45478356	21	-	26627737	RPE1	viability after 15 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.6479658712522693	[448]	[28,362]	4	hSpCas9	negative selection	1310432
45405459	45405482	21	-	26627737	RPE1	viability after 18 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	1.9072611582769063	[106]	[131,82]	8	hSpCas9	negative selection	1392742
45455724	45455747	21	-	26627737	RPE1	viability after 18 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	0.12447663387342434	[1059]	[175,456]	0	hSpCas9	negative selection	1392743
45468424	45468447	21	+	26627737	RPE1	viability after 18 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.4357282196426292	[904]	[252,412]	2	hSpCas9	negative selection	1392744
45473903	45473926	21	+	26627737	RPE1	viability after 18 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.7561742479127651	[766]	[308,392]	4	hSpCas9	negative selection	1392745
45475477	45475500	21	+	26627737	RPE1	viability after 18 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.43554678614835407	[391]	[217,62]	2	hSpCas9	negative selection	1392746
45478333	45478356	21	-	26627737	RPE1	viability after 18 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.4548361042646798	[448]	[80,256]	3	hSpCas9	negative selection	1392747
45405459	45405482	21	-	26627737	HeLa	viability after 8 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.6399079796552911	[186]	[86,118,162]	5	hSpCas9	negative selection	1475057
45455724	45455747	21	-	26627737	HeLa	viability after 8 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.8892728658746607	[1007]	[80,326,265]	-7	hSpCas9	negative selection	1475058
45468424	45468447	21	+	26627737	HeLa	viability after 8 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	-0.25286910070019086	[821]	[424,276,230]	-2	hSpCas9	negative selection	1475059
45473903	45473926	21	+	26627737	HeLa	viability after 8 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.4723415332852378	[278]	[170,138,193]	4	hSpCas9	negative selection	1475060
45475477	45475500	21	+	26627737	HeLa	viability after 8 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	-0.1511887390515409	[376]	[32,267,118]	-1	hSpCas9	negative selection	1475061
45478333	45478356	21	-	26627737	HeLa	viability after 8 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.40055671553465577	[427]	[108,177,129]	-4	hSpCas9	negative selection	1475062
45405459	45405482	21	-	26627737	HeLa	viability after 12 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.22090035823231424	[186]	[129,17,130]	2	hSpCas9	negative selection	1557372
45455724	45455747	21	-	26627737	HeLa	viability after 12 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-1.4864062356229597	[1007]	[174,174,93]	-8	hSpCas9	negative selection	1557373
45468424	45468447	21	+	26627737	HeLa	viability after 12 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.27474299425134974	[821]	[521,364,353]	2	hSpCas9	negative selection	1557374
45473903	45473926	21	+	26627737	HeLa	viability after 12 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	1.1122986098385852	[278]	[186,135,434]	7	hSpCas9	negative selection	1557375
45475477	45475500	21	+	26627737	HeLa	viability after 12 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.09523313203131181	[376]	[57,214,217]	0	hSpCas9	negative selection	1557376
45478333	45478356	21	-	26627737	HeLa	viability after 12 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-1.5038136882592912	[427]	[4,75,102]	-8	hSpCas9	negative selection	1557377
45405459	45405482	21	-	26627737	HeLa	viability after 15 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.031104414270137326	[186]	[30,160,38]	0	hSpCas9	negative selection	1639687
45455724	45455747	21	-	26627737	HeLa	viability after 15 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.9970666808531683	[1007]	[87,255,279]	-7	hSpCas9	negative selection	1639688
45468424	45468447	21	+	26627737	HeLa	viability after 15 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.007227629620626397	[821]	[281,350,379]	0	hSpCas9	negative selection	1639689
45473903	45473926	21	+	26627737	HeLa	viability after 15 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	1.7594980322005724	[278]	[354,342,461]	9	hSpCas9	negative selection	1639690
45475477	45475500	21	+	26627737	HeLa	viability after 15 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.18061433633233548	[376]	[77,102,355]	1	hSpCas9	negative selection	1639691
45478333	45478356	21	-	26627737	HeLa	viability after 15 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.16026331777402414	[427]	[44,173,257]	-1	hSpCas9	negative selection	1639692
45405459	45405482	21	-	26627737	HeLa	viability after 18 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.034440767063884214	[186]	[22,130,38]	0	hSpCas9	negative selection	1722002
45455724	45455747	21	-	26627737	HeLa	viability after 18 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.9985998727910685	[1007]	[60,208,279]	-7	hSpCas9	negative selection	1722003
45468424	45468447	21	+	26627737	HeLa	viability after 18 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.03707978873022677	[821]	[192,302,379]	0	hSpCas9	negative selection	1722004
45473903	45473926	21	+	26627737	HeLa	viability after 18 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	1.7945484768215998	[278]	[250,290,461]	9	hSpCas9	negative selection	1722005
45475477	45475500	21	+	26627737	HeLa	viability after 18 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.2136417747359065	[376]	[57,87,355]	1	hSpCas9	negative selection	1722006
45478333	45478356	21	-	26627737	HeLa	viability after 18 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.14537872476134392	[427]	[26,151,257]	-1	hSpCas9	negative selection	1722007
45405459	45405482	21	-	26627737	HCT116	viability after 6 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-6.569144482137512	[603]	[0,0]	-9	hSpCas9	negative selection	1804317
45455724	45455747	21	-	26627737	HCT116	viability after 6 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-1.13390537590079	[1500]	[151,82]	-6	hSpCas9	negative selection	1804318
45468424	45468447	21	+	26627737	HCT116	viability after 6 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.103489434020122	[1467]	[459,130]	0	hSpCas9	negative selection	1804319
45473903	45473926	21	+	26627737	HCT116	viability after 6 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.5001422767454603	[918]	[184,214]	3	hSpCas9	negative selection	1804320
45475477	45475500	21	+	26627737	HCT116	viability after 6 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	1.9569839007048784	[269]	[187,151]	8	hSpCas9	negative selection	1804321
45478333	45478356	21	-	26627737	HCT116	viability after 6 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-2.244484009462014	[220]	[16,1]	-8	hSpCas9	negative selection	1804322
45405459	45405482	21	-	26627737	HCT116	viability after 8 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-0.5226677240535769	[162]	[83,45,57]	-6	hSpCas9	negative selection	1886632
45455724	45455747	21	-	26627737	HCT116	viability after 8 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.8598834863535243	[621]	[140,178,244]	-8	hSpCas9	negative selection	1886633
45468424	45468447	21	+	26627737	HCT116	viability after 8 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.05192738693739973	[791]	[603,391,364]	0	hSpCas9	negative selection	1886634
45473903	45473926	21	+	26627737	HCT116	viability after 8 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	-0.4137072611398501	[608]	[304,142,307]	-5	hSpCas9	negative selection	1886635
45475477	45475500	21	+	26627737	HCT116	viability after 8 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.24390290254338487	[167]	[78,112,135]	2	hSpCas9	negative selection	1886636
45478333	45478356	21	-	26627737	HCT116	viability after 8 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.2418927435206364	[111]	[89,35,92]	2	hSpCas9	negative selection	1886637
45405459	45405482	21	-	26627737	HCT116	viability after 9 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-2.3220869221700973	[603]	[5,52]	-9	hSpCas9	negative selection	1968947
45455724	45455747	21	-	26627737	HCT116	viability after 9 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.7817515661051941	[1500]	[126,316]	-5	hSpCas9	negative selection	1968948
45468424	45468447	21	+	26627737	HCT116	viability after 9 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.6161854178983384	[1467]	[568,625]	4	hSpCas9	negative selection	1968949
45473903	45473926	21	+	26627737	HCT116	viability after 9 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.49374231981157257	[918]	[287,390]	3	hSpCas9	negative selection	1968950
45475477	45475500	21	+	26627737	HCT116	viability after 9 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.3402473126811645	[269]	[40,130]	2	hSpCas9	negative selection	1968951
45478333	45478356	21	-	26627737	HCT116	viability after 9 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.8599451864908365	[220]	[60,9]	-6	hSpCas9	negative selection	1968952
45405459	45405482	21	-	26627737	HCT116	viability after 12 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-0.22981817991680398	[162]	[65,82,70]	-2	hSpCas9	negative selection	2051262
45455724	45455747	21	-	26627737	HCT116	viability after 12 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.7549462487557455	[621]	[201,219,158]	-7	hSpCas9	negative selection	2051263
45468424	45468447	21	+	26627737	HCT116	viability after 12 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	-0.10730233616687834	[791]	[490,387,270]	-1	hSpCas9	negative selection	2051264
45473903	45473926	21	+	26627737	HCT116	viability after 12 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	-0.4568868639487902	[608]	[292,139,258]	-5	hSpCas9	negative selection	2051265
45475477	45475500	21	+	26627737	HCT116	viability after 12 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	-0.034521956134731635	[167]	[80,124,53]	0	hSpCas9	negative selection	2051266
45478333	45478356	21	-	26627737	HCT116	viability after 12 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.014634684425456124	[111]	[71,33,66]	0	hSpCas9	negative selection	2051267
45405459	45405482	21	-	26627737	HCT116	viability after 15 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-0.7227874375429801	[162]	[94,37,41]	-6	hSpCas9	negative selection	2133577
45455724	45455747	21	-	26627737	HCT116	viability after 15 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.8362210312375942	[621]	[213,276,111]	-7	hSpCas9	negative selection	2133578
45468424	45468447	21	+	26627737	HCT116	viability after 15 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	-0.06484972557572899	[791]	[489,530,291]	0	hSpCas9	negative selection	2133579
45473903	45473926	21	+	26627737	HCT116	viability after 15 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	-0.8662629217583204	[608]	[307,196,85]	-7	hSpCas9	negative selection	2133580
45475477	45475500	21	+	26627737	HCT116	viability after 15 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.39973620207220817	[167]	[103,145,128]	4	hSpCas9	negative selection	2133581
45478333	45478356	21	-	26627737	HCT116	viability after 15 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.05176174239932485	[111]	[63,11,122]	0	hSpCas9	negative selection	2133582
45405459	45405482	21	-	26627737	HCT116	viability after 18 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-1.0226761858630817	[162]	[18,49,46]	-7	hSpCas9	negative selection	2215892
45455724	45455747	21	-	26627737	HCT116	viability after 18 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.4649502881887331	[621]	[122,218,315]	-4	hSpCas9	negative selection	2215893
45468424	45468447	21	+	26627737	HCT116	viability after 18 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.13856162309075337	[791]	[316,536,401]	1	hSpCas9	negative selection	2215894
45473903	45473926	21	+	26627737	HCT116	viability after 18 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	-0.2898904272847428	[608]	[381,186,152]	-3	hSpCas9	negative selection	2215895
45475477	45475500	21	+	26627737	HCT116	viability after 18 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.5503372068511332	[167]	[73,152,127]	4	hSpCas9	negative selection	2215896
45478333	45478356	21	-	26627737	HCT116	viability after 18 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.7617893090631441	[111]	[54,24,204]	6	hSpCas9	negative selection	2215897
45455408	45455431	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGACAGCCGGCCAGAGGCTGGG	COL18A1	ENSG00000182871	-3.1766042707617315	[334,62]	[3,4]	-9	dCas9-VP64	positive selection	2457243
45455357	45455380	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCACCAGCCTTGGAATCAAGG	COL18A1	ENSG00000182871	1.9542207437398373	[283,171]	[43,355]	7	dCas9-VP64	positive selection	2457244
45455332	45455355	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTGGAACCCCCGGGTGCTGGG	COL18A1	ENSG00000182871	-0.20217382575517773	[23,53]	[1,11]	-1	dCas9-VP64	positive selection	2457245
45455408	45455431	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGACAGCCGGCCAGAGGCTGGG	COL18A1	ENSG00000182871	0.18716072830361474	[32,45]	[20,7]	1	dCas9-VP64	positive selection	2552498
45455357	45455380	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCACCAGCCTTGGAATCAAGG	COL18A1	ENSG00000182871	0.979041048244051	[189,890]	[446,247]	6	dCas9-VP64	positive selection	2552499
45455332	45455355	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTGGAACCCCCGGGTGCTGGG	COL18A1	ENSG00000182871	0.40301569428578443	[84,29]	[38,10]	3	dCas9-VP64	positive selection	2552500
45478332	45478355	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGGCTTTCCGTCTTCACCGGGG	COL18A1	ENSG00000182871	0.1834098907867712	[3,3]	[3,3]	4	hSpCas9	positive selection	2980386
45405437	45405460	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGCTGCTCGGGGTCCGCGCGG	COL18A1	ENSG00000182871	0.6928041781741348	[2,3]	[2,5]	9	hSpCas9	positive selection	2980387
45468496	45468519	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGGCGTGAAGCTCTCTGGGG	COL18A1	ENSG00000182871	-0.09200084809705958	[4,4]	[3,3]	-1	hSpCas9	positive selection	2980388
45480513	45480536	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAAGGGCCACTCACCCGCAGGG	COL18A1	ENSG00000182871	0.44330897418094084	[3,3]	[5,2]	8	hSpCas9	positive selection	2980389
45478332	45478355	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGGCTTTCCGTCTTCACCGGGG	COL18A1	ENSG00000182871	-0.49890368232346066	[3,3]	[2,0]	-7	hSpCas9	positive selection	3048244
45405437	45405460	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGCTGCTCGGGGTCCGCGCGG	COL18A1	ENSG00000182871	0.3761287401366624	[2,2]	[1,2]	6	hSpCas9	positive selection	3048245
45468496	45468519	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGGCGTGAAGCTCTCTGGGG	COL18A1	ENSG00000182871	0.3191960197430296	[4,4]	[4,3]	5	hSpCas9	positive selection	3048246
45480513	45480536	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAAGGGCCACTCACCCGCAGGG	COL18A1	ENSG00000182871	-0.16023366318587284	[3,3]	[2,1]	-2	hSpCas9	positive selection	3048247
45405412	45405435		-	24336571	A375	resistance to PLX after 7 days	CCAGGGGCGCGAGCACGTCCAGG	COL18A1	ENSG00000182871	-0.9974697239993504	[6,6]	[2,2]	-9	hSpCas9	positive selection	3106653
45405436	45405459		-	24336571	A375	resistance to PLX after 7 days	CCGCGCGGACCCCGAGCAGCAGG	COL18A1	ENSG00000182871	0.15934393399607916	[5,5]	[5,6]	5	hSpCas9	positive selection	3106655
45405412	45405435		-	24336571	A375	resistance to PLX after 14 days	CCAGGGGCGCGAGCACGTCCAGG	COL18A1	ENSG00000182871	-0.11359858511676135	[6,4]	[1,1]	-1	hSpCas9	positive selection	3164446
45405436	45405459		-	24336571	A375	resistance to PLX after 14 days	CCGCGCGGACCCCGAGCAGCAGG	COL18A1	ENSG00000182871	0.2269298695767744	[8,6]	[3,3]	2	hSpCas9	positive selection	3164448
45405412	45405435		-	24336571	A375	viability after 7 days	CCAGGGGCGCGAGCACGTCCAGG	COL18A1	ENSG00000182871	-0.09987307379108012	[7]	[6,6]	-1	hSpCas9	negative selection	3222239
45405436	45405459		-	24336571	A375	viability after 7 days	CCGCGCGGACCCCGAGCAGCAGG	COL18A1	ENSG00000182871	0.0935390085679455	[5]	[5,5]	1	hSpCas9	negative selection	3222241
45405412	45405435		-	24336571	A375	viability after 14 days	CCAGGGGCGCGAGCACGTCCAGG	COL18A1	ENSG00000182871	-0.3247209701028949	[7]	[6,4]	-4	hSpCas9	negative selection	3280032
45405436	45405459		-	24336571	A375	viability after 14 days	CCGCGCGGACCCCGAGCAGCAGG	COL18A1	ENSG00000182871	0.5762892647065667	[5]	[8,6]	7	hSpCas9	negative selection	3280034
45456061	45456084	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	2.4737394553211804	[33,20]	[0,0]	8	hSpCas9	positive selection	3343992
45455860	45455883	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	2.618273522438283	[161,186]	[3,9]	8	hSpCas9	positive selection	3343993
45405412	45405435	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	-0.819489385604996	[269,269]	[0,0]	-5	hSpCas9	positive selection	3363217
45478332	45478355	21	-	26780180	HT29	viability (Avana library 4 designs)	CCGGCTTTCCGTCTTCACCGGGG	COL18A1	ENSG00000182871	0.545671075303855	[]	[]	2	hSpCas9	negative selection	3416837
45405436	45405459	21	+	26780180	HT29	viability (Avana library 4 designs)	CCTGCTGCTCGGGGTCCGCGCGG	COL18A1	ENSG00000182871	1.23501600074989	[]	[]	5	hSpCas9	negative selection	3416838
45468495	45468518	21	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGGCGTGAAGCTCTCTGGGG	COL18A1	ENSG00000182871	0.342050209432384	[]	[]	1	hSpCas9	negative selection	3416839
45480513	45480536	21	-	26780180	HT29	viability (Avana library 4 designs)	TTAAGGGCCACTCACCCGCAGGG	COL18A1	ENSG00000182871	0.741686699722708	[]	[]	3	hSpCas9	negative selection	3416840
45478332	45478355	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGGCTTTCCGTCTTCACCGGGG	COL18A1	ENSG00000182871	2.21069116532589	[]	[]	3	hSpCas9	negative selection	3494559
45480513	45480536	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAGGGCCACTCACCCGCAGGG	COL18A1	ENSG00000182871	5.51437492831244	[]	[]	8	hSpCas9	negative selection	3494560
45405436	45405459	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCTGCTCGGGGTCCGCGCGG	COL18A1	ENSG00000182871	5.23253429633127	[]	[]	8	hSpCas9	negative selection	3494561
45468495	45468518	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGCGTGAAGCTCTCTGGGG	COL18A1	ENSG00000182871	4.63441134795126	[]	[]	7	hSpCas9	negative selection	3494562
45477426	45477449	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAGATTCTGTCTCCACGTGG	COL18A1	ENSG00000182871	4.42476147788945	[]	[]	7	hSpCas9	negative selection	3494563
45477475	45477498	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGGCCTTACCTCTTTCACGCGG	COL18A1	ENSG00000182871	2.1029175877418	[]	[]	3	hSpCas9	negative selection	3494564
45478332	45478355	21	-	26780180	A375	viability (Avana lentiGuide)	CCGGCTTTCCGTCTTCACCGGGG	COL18A1	ENSG00000182871	-2.82163330950823	[]	[]	-5	hSpCas9	negative selection	3603218
45480513	45480536	21	-	26780180	A375	viability (Avana lentiGuide)	TTAAGGGCCACTCACCCGCAGGG	COL18A1	ENSG00000182871	1.16285848393363	[]	[]	1	hSpCas9	negative selection	3603219
45405436	45405459	21	+	26780180	A375	viability (Avana lentiGuide)	CCTGCTGCTCGGGGTCCGCGCGG	COL18A1	ENSG00000182871	11.3166734170853	[]	[]	7	hSpCas9	negative selection	3603220
45468495	45468518	21	+	26780180	A375	viability (Avana lentiGuide)	GCTGGGCGTGAAGCTCTCTGGGG	COL18A1	ENSG00000182871	-0.896264801742865	[]	[]	-1	hSpCas9	negative selection	3603221
45477426	45477449	21	+	26780180	A375	viability (Avana lentiGuide)	GCTCAGATTCTGTCTCCACGTGG	COL18A1	ENSG00000182871	-2.63046224490543	[]	[]	-5	hSpCas9	negative selection	3603222
45477475	45477498	21	-	26780180	A375	viability (Avana lentiGuide)	GTGGCCTTACCTCTTTCACGCGG	COL18A1	ENSG00000182871	4.05963718987709	[]	[]	4	hSpCas9	negative selection	3603223
45478332	45478355	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGGCTTTCCGTCTTCACCGGGG	COL18A1	ENSG00000182871	0.21562051105688557	[4]	[5,5]	6	hSpCas9	positive selection	3711877
45480513	45480536	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAGGGCCACTCACCCGCAGGG	COL18A1	ENSG00000182871	0.08501898779567872	[5]	[5,4]	2	hSpCas9	positive selection	3711878
45405436	45405459	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCTGCTCGGGGTCCGCGCGG	COL18A1	ENSG00000182871	0.1520036674878103	[3]	[4,2]	4	hSpCas9	positive selection	3711879
45468495	45468518	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGCGTGAAGCTCTCTGGGG	COL18A1	ENSG00000182871	0.2551704289950191	[5]	[6,6]	7	hSpCas9	positive selection	3711880
45477426	45477449	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAGATTCTGTCTCCACGTGG	COL18A1	ENSG00000182871	0.3124650330946442	[4]	[6,5]	8	hSpCas9	positive selection	3711881
45477475	45477498	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGGCCTTACCTCTTTCACGCGG	COL18A1	ENSG00000182871	-0.088378834421101	[4]	[5,2]	-1	hSpCas9	positive selection	3711882
45478332	45478355	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGGCTTTCCGTCTTCACCGGGG	COL18A1	ENSG00000182871	0.21641009759418348	[5]	[5,4]	5	hSpCas9	positive selection	3820484
45480513	45480536	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAGGGCCACTCACCCGCAGGG	COL18A1	ENSG00000182871	-0.6415001477756332	[5]	[2,2]	-7	hSpCas9	positive selection	3820485
45405436	45405459	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCTGCTCGGGGTCCGCGCGG	COL18A1	ENSG00000182871	-0.6027580868605978	[4]	[2,2]	-6	hSpCas9	positive selection	3820486
45468495	45468518	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGCGTGAAGCTCTCTGGGG	COL18A1	ENSG00000182871	0.20062349277656488	[6]	[6,5]	5	hSpCas9	positive selection	3820487
45477426	45477449	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAGATTCTGTCTCCACGTGG	COL18A1	ENSG00000182871	0.21868323663855888	[5]	[6,5]	5	hSpCas9	positive selection	3820488
45477475	45477498	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGGCCTTACCTCTTTCACGCGG	COL18A1	ENSG00000182871	-0.02440852579154819	[4]	[3,4]	0	hSpCas9	positive selection	3820489
45405412	45405435	21	+	26780180	A375	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.550663708153096	[]	[]	1	hSpCas9	negative selection	3928488
45455860	45455883	21	+	26780180	A375	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.695110254297574	[]	[]	2	hSpCas9	negative selection	3928489
45456061	45456084	21	+	26780180	A375	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	1.30404398004904	[]	[]	7	hSpCas9	negative selection	3928490
45405412	45405435	21	+	26780180	HT29	viability (GeCKOv2 library)	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.944627274099465	[]	[]	4	hSpCas9	negative selection	4036454
45455860	45455883	21	+	26780180	HT29	viability (GeCKOv2 library)	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	1.08554172531669	[]	[]	5	hSpCas9	negative selection	4036455
45456061	45456084	21	+	26780180	HT29	viability (GeCKOv2 library)	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.865640127570209	[]	[]	3	hSpCas9	negative selection	4036456
45405412	45405435	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGGGGCGCGAGCACGTCCAGG	COL18A1	ENSG00000182871	-0.23004251927046898	[2]	[1,0]	-5	hSpCas9	positive selection	4128848
45405436	45405459	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCGCGGACCCCGAGCAGCAGG	COL18A1	ENSG00000182871	-0.16178500588584077	[2]	[0,1]	-4	hSpCas9	positive selection	4128850
45405412	45405435	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGGGGCGCGAGCACGTCCAGG	COL18A1	ENSG00000182871	0.735846983186752	[2]	[3,2,2,0]	5	hSpCas9	positive selection	4192870
45405436	45405459	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCGCGGACCCCGAGCAGCAGG	COL18A1	ENSG00000182871	-0.7866787048100945	[3]	[0,0,1,0]	-9	hSpCas9	positive selection	4192872
45456061	45456084	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.06828248964581157	[2]	[2,0]	-1	hSpCas9	positive selection	4264220
45455860	45455883	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.2259388473492546	[3]	[3,3]	4	hSpCas9	positive selection	4264221
45405412	45405435	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.11848173396134126	[3]	[3,2]	2	hSpCas9	positive selection	4328491
45480488	45480510	21	+	27760321	OCIAML3	viability	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	0.0897294957648418	[955,798]	[676,792]	1	hSpCas9	negative selection	4390796
45468600	45468622	21	-	27760321	OCIAML3	viability	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	-0.24488478838045913	[317,263]	[195,184]	-3	hSpCas9	negative selection	4390797
45477465	45477487	21	-	27760321	OCIAML3	viability	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.4716889125201964	[947,842]	[822,1160]	5	hSpCas9	negative selection	4390798
45477882	45477904	21	-	27760321	OCIAML3	viability	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	-0.0029591203551722067	[840,730]	[525,723]	0	hSpCas9	negative selection	4390799
45479944	45479966	21	+	27760321	OCIAML3	viability	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.9582232716678267	[401,303]	[393,711]	9	hSpCas9	negative selection	4390800
45480488	45480510	21	+	27760321	OCIAML2	viability	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	0.13703949134086013	[955,798]	[776,777]	1	hSpCas9	negative selection	4474259
45468600	45468622	21	-	27760321	OCIAML2	viability	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	-0.7352449239023803	[317,263]	[148,129]	-6	hSpCas9	negative selection	4474260
45477465	45477487	21	-	27760321	OCIAML2	viability	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.11362319810349253	[947,842]	[675,922]	1	hSpCas9	negative selection	4474261
45477882	45477904	21	-	27760321	OCIAML2	viability	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.1326408394842914	[840,730]	[621,791]	1	hSpCas9	negative selection	4474262
45479944	45479966	21	+	27760321	OCIAML2	viability	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.1722607271891765	[401,303]	[231,433]	2	hSpCas9	negative selection	4474263
45480488	45480510	21	+	27760321	MV411	viability	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	-0.16124175501007443	[955,798]	[428,645]	-1	hSpCas9	negative selection	4557722
45468600	45468622	21	-	27760321	MV411	viability	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	-1.3774877095413145	[317,263]	[61,90]	-7	hSpCas9	negative selection	4557723
45477465	45477487	21	-	27760321	MV411	viability	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.5128217515126856	[947,842]	[707,1042]	3	hSpCas9	negative selection	4557724
45477882	45477904	21	-	27760321	MV411	viability	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.36645754069973735	[840,730]	[463,971]	2	hSpCas9	negative selection	4557725
45479944	45479966	21	+	27760321	MV411	viability	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.13041406096161956	[401,303]	[150,405]	0	hSpCas9	negative selection	4557726
45480488	45480510	21	+	27760321	HL60	viability	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	-0.3574057786327386	[955,798]	[465,653]	-4	hSpCas9	negative selection	4641185
45468600	45468622	21	-	27760321	HL60	viability	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	-0.36491532068714627	[317,263]	[242,120]	-4	hSpCas9	negative selection	4641186
45477465	45477487	21	-	27760321	HL60	viability	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.1219652649755254	[947,842]	[871,712]	1	hSpCas9	negative selection	4641187
45477882	45477904	21	-	27760321	HL60	viability	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	-0.07437162937462516	[840,730]	[518,702]	-1	hSpCas9	negative selection	4641188
45479944	45479966	21	+	27760321	HL60	viability	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.2521728880401715	[401,303]	[328,352]	3	hSpCas9	negative selection	4641189
45480488	45480510	21	+	27760321	HT1080	viability	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	-1.099144105772646	[798,623]	[159,101]	-4	hSpCas9	negative selection	4724648
45468600	45468622	21	-	27760321	HT1080	viability	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	2.6793242673735675	[263,205]	[581,618]	9	hSpCas9	negative selection	4724649
45477465	45477487	21	-	27760321	HT1080	viability	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	-1.416141798209876	[842,657]	[59,168]	-5	hSpCas9	negative selection	4724650
45477882	45477904	21	-	27760321	HT1080	viability	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.860266884528295	[730,570]	[308,647]	4	hSpCas9	negative selection	4724651
45479944	45479966	21	+	27760321	HT1080	viability	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	2.318817977582074	[303,236]	[623,442]	9	hSpCas9	negative selection	4724652
45480488	45480510	21	+	27760321	HT29	viability after 7 days	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	-0.14516328234815556	[798,623]	[1176,766,593]	-2	hSpCas9	negative selection	4808111
45468600	45468622	21	-	27760321	HT29	viability after 7 days	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	0.1947861850973016	[263,205]	[389,267,383]	3	hSpCas9	negative selection	4808112
45477465	45477487	21	-	27760321	HT29	viability after 7 days	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.35621924216325906	[842,657]	[1504,867,1364]	5	hSpCas9	negative selection	4808113
45477882	45477904	21	-	27760321	HT29	viability after 7 days	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.04235927469659362	[730,570]	[905,791,891]	0	hSpCas9	negative selection	4808114
45479944	45479966	21	+	27760321	HT29	viability after 7 days	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.4215646077628287	[303,236]	[440,449,500]	6	hSpCas9	negative selection	4808115
45480488	45480510	21	+	27760321	HT29	viability after 25 days	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	0.03249285874033281	[798,623]	[908,798,774]	0	hSpCas9	negative selection	4891574
45468600	45468622	21	-	27760321	HT29	viability after 25 days	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	0.6156894653378061	[263,205]	[409,222,622]	7	hSpCas9	negative selection	4891575
45477465	45477487	21	-	27760321	HT29	viability after 25 days	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.3315833416635676	[842,657]	[824,1169,1277]	3	hSpCas9	negative selection	4891576
45477882	45477904	21	-	27760321	HT29	viability after 25 days	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.26512123269767707	[730,570]	[888,874,919]	2	hSpCas9	negative selection	4891577
45479944	45479966	21	+	27760321	HT29	viability after 25 days	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.5782834315589859	[303,236]	[424,371,603]	6	hSpCas9	negative selection	4891578
45480488	45480510	21	+	27760321	HT29	viability after 22 days	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	0.05863004965852081	[798,623]	[763,1004,802]	0	hSpCas9	negative selection	4975037
45468600	45468622	21	-	27760321	HT29	viability after 22 days	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	0.18972252776246556	[263,205]	[233,239,458]	2	hSpCas9	negative selection	4975038
45477465	45477487	21	-	27760321	HT29	viability after 22 days	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.20920774805783693	[842,657]	[1034,775,1198]	2	hSpCas9	negative selection	4975039
45477882	45477904	21	-	27760321	HT29	viability after 22 days	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.2806653918137423	[730,570]	[686,1134,926]	3	hSpCas9	negative selection	4975040
45479944	45479966	21	+	27760321	HT29	viability after 22 days	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.38546537184600527	[303,236]	[346,369,510]	4	hSpCas9	negative selection	4975041
45480488	45480510	21	+	27760321	HT29	viability after 19 days	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	-0.05193835438604544	[798,623]	[971,1045,371]	0	hSpCas9	negative selection	5058500
45468600	45468622	21	-	27760321	HT29	viability after 19 days	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	0.4327384278160118	[263,205]	[365,187,527]	4	hSpCas9	negative selection	5058501
45477465	45477487	21	-	27760321	HT29	viability after 19 days	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.04476906711812023	[842,657]	[1053,620,993]	0	hSpCas9	negative selection	5058502
45477882	45477904	21	-	27760321	HT29	viability after 19 days	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	-0.13707321585788168	[730,570]	[698,868,472]	-1	hSpCas9	negative selection	5058503
45479944	45479966	21	+	27760321	HT29	viability after 19 days	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.5077146206008265	[303,236]	[458,363,495]	5	hSpCas9	negative selection	5058504
45480488	45480510	21	+	27760321	HT29	viability after 16 days	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	0.2084968161256162	[798,623]	[1205,934,644]	2	hSpCas9	negative selection	5141963
45468600	45468622	21	-	27760321	HT29	viability after 16 days	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	-0.045245821345882176	[263,205]	[316,186,267]	0	hSpCas9	negative selection	5141964
45477465	45477487	21	-	27760321	HT29	viability after 16 days	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	-0.06502421206139808	[842,657]	[758,715,930]	0	hSpCas9	negative selection	5141965
45477882	45477904	21	-	27760321	HT29	viability after 16 days	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.47688341272417745	[730,570]	[1204,976,877]	5	hSpCas9	negative selection	5141966
45479944	45479966	21	+	27760321	HT29	viability after 16 days	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.7138943729347138	[303,236]	[708,422,378]	8	hSpCas9	negative selection	5141967
45480488	45480510	21	+	27760321	HT29	viability after 13 days	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	0.27681082518525857	[798,623]	[963,1205,839]	3	hSpCas9	negative selection	5225426
45468600	45468622	21	-	27760321	HT29	viability after 13 days	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	0.2615752163334193	[263,205]	[244,415,319]	3	hSpCas9	negative selection	5225427
45477465	45477487	21	-	27760321	HT29	viability after 13 days	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	-0.048327988168050284	[842,657]	[683,792,1036]	0	hSpCas9	negative selection	5225428
45477882	45477904	21	-	27760321	HT29	viability after 13 days	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	-0.09499689464832639	[730,570]	[743,768,613]	-1	hSpCas9	negative selection	5225429
45479944	45479966	21	+	27760321	HT29	viability after 13 days	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.6830323200584411	[303,236]	[468,719,332]	8	hSpCas9	negative selection	5225430
45480488	45480510	21	+	27760321	HT29	viability after 10 days	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	-0.04890186840569444	[798,623]	[852,997,731]	0	hSpCas9	negative selection	5308889
45468600	45468622	21	-	27760321	HT29	viability after 10 days	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	0.3079777299182968	[263,205]	[350,295,438]	4	hSpCas9	negative selection	5308890
45477465	45477487	21	-	27760321	HT29	viability after 10 days	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	0.13850401133867507	[842,657]	[975,730,1370]	1	hSpCas9	negative selection	5308891
45477882	45477904	21	-	27760321	HT29	viability after 10 days	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.3105767080549724	[730,570]	[1089,1108,831]	4	hSpCas9	negative selection	5308892
45479944	45479966	21	+	27760321	HT29	viability after 10 days	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	0.626788856357298	[303,236]	[603,397,557]	8	hSpCas9	negative selection	5308893
45480488	45480510	21	+	27760321	MOLM13	viability	TCTGGCTTCGGGGGCGATCTGG	COL18A1	ENSG00000182871	0.8582007331414776	[955,798]	[532,1200]	6	hSpCas9	negative selection	5392352
45468600	45468622	21	-	27760321	MOLM13	viability	CCACTGGCCGACGAAGGCGGGG	COL18A1	ENSG00000182871	-0.40918454557161643	[317,263]	[188,66]	-3	hSpCas9	negative selection	5392353
45477465	45477487	21	-	27760321	MOLM13	viability	TCTTTCACGCGGCCCCCAGGGG	COL18A1	ENSG00000182871	-0.0665658357591633	[947,842]	[424,529]	0	hSpCas9	negative selection	5392354
45477882	45477904	21	-	27760321	MOLM13	viability	CGGGGACAGTTTGCAACGCTGG	COL18A1	ENSG00000182871	0.05980266603951501	[840,730]	[701,255]	0	hSpCas9	negative selection	5392355
45479944	45479966	21	+	27760321	MOLM13	viability	GTAGGTCCCAAGGGCGACAAGG	COL18A1	ENSG00000182871	-0.5739197179732378	[401,303]	[102,157]	-4	hSpCas9	negative selection	5392356
45455988	45456011	21	-	27661255	K562	viability	GGTGCTGGAAGGCCCAGCGAGGG	COL18A1	ENSG00000182871	0.4208195188782508	[511,632]	[604,613]	9	dCas9-KRAB	negative selection	5472004
45456027	45456050	21	-	27661255	K562	viability	GCCACGGCTGGGCCAGAGAGTGG	COL18A1	ENSG00000182871	0.16714312878367377	[1591,1865]	[1595,1503]	6	dCas9-KRAB	negative selection	5472005
45456038	45456061	21	-	27661255	K562	viability	GAGCTAGGAATGCCACGGCTGGG	COL18A1	ENSG00000182871	0.21147190527330328	[711,929]	[833,688]	7	dCas9-KRAB	negative selection	5472006
45456069	45456092	21	-	27661255	K562	viability	GGTGCCAGCCTCGGTTGTGTGGG	COL18A1	ENSG00000182871	0.05128053872012872	[1078,1412]	[1102,960]	1	dCas9-KRAB	negative selection	5472007
45456061	45456084	21	+	27260156	BXPC3	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.11986998763954881	[214]	[303,242,197,219]	2	hSpCas9	negative selection	5536680
45455860	45455883	21	+	27260156	BXPC3	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.17626556571999435	[704]	[466,745,692,722]	-4	hSpCas9	negative selection	5536681
45405412	45405435	21	+	27260156	BXPC3	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.28732111194001686	[604]	[823,653,717,902]	6	hSpCas9	negative selection	5600951
45456061	45456084	21	+	27260156	A673	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.23636398726842534	[214]	[206,208,236,221]	-5	hSpCas9	negative selection	5657931
45455860	45455883	21	+	27260156	A673	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.061864978714653684	[704]	[1002,647,817,798]	-1	hSpCas9	negative selection	5657932
45405412	45405435	21	+	27260156	A673	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.3115366067851352	[604]	[1080,739,909,897]	7	hSpCas9	negative selection	5722202
45456061	45456084	21	+	27260156	A375	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.3595871936209787	[214]	[394,103,160,119]	-5	hSpCas9	negative selection	5779182
45455860	45455883	21	+	27260156	A375	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.17647208434463618	[704]	[745,610,694,830]	-3	hSpCas9	negative selection	5779183
45405412	45405435	21	+	27260156	A375	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.21734770534677283	[604]	[852,983,695,777]	3	hSpCas9	negative selection	5843453
45456061	45456084	21	+	27260156	COLO741	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.10332927579036588	[214]	[303,266,312]	2	hSpCas9	negative selection	5900433
45455860	45455883	21	+	27260156	COLO741	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.002526628042170298	[704]	[1006,818,879]	0	hSpCas9	negative selection	5900434
45405412	45405435	21	+	27260156	COLO741	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.18010384924785883	[604]	[829,906,883]	4	hSpCas9	negative selection	5964704
45456061	45456084	21	+	27260156	CAL120	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.5959688312385267	[214]	[161,262,104]	-7	hSpCas9	negative selection	6021684
45455860	45455883	21	+	27260156	CAL120	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.007584012863754319	[704]	[798,1012,821]	0	hSpCas9	negative selection	6021685
45405412	45405435	21	+	27260156	CAL120	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.42867243816612033	[604]	[960,1184,887]	6	hSpCas9	negative selection	6085955
45456061	45456084	21	+	27260156	CADOES1	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.07946736954333122	[214]	[73,237,137,311]	-1	hSpCas9	negative selection	6142935
45455860	45455883	21	+	27260156	CADOES1	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.3104421784233247	[704]	[441,583,542,546]	-5	hSpCas9	negative selection	6142936
45405412	45405435	21	+	27260156	CADOES1	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.21839461363044266	[604]	[654,633,586,745]	3	hSpCas9	negative selection	6207206
45456061	45456084	21	+	27260156	EWS502	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.4258645169275177	[214]	[208,142,126,195]	-6	hSpCas9	negative selection	6264186
45455860	45455883	21	+	27260156	EWS502	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.25946713491922435	[704]	[758,819,1064,953]	4	hSpCas9	negative selection	6264187
45405412	45405435	21	+	27260156	EWS502	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.35293902360312035	[604]	[558,749,969,1043]	6	hSpCas9	negative selection	6328457
45456061	45456084	21	+	27260156	EW8	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.26215103408788254	[214]	[279,103,148,61]	-5	hSpCas9	negative selection	6385437
45455860	45455883	21	+	27260156	EW8	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.06635991089432569	[704]	[616,799,311,500]	-1	hSpCas9	negative selection	6385438
45405412	45405435	21	+	27260156	EW8	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.28916277750133657	[604]	[620,616,534,634]	5	hSpCas9	negative selection	6449708
45456061	45456084	21	+	27260156	CORL105	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.48424973496780455	[214]	[335,273,396,408]	8	hSpCas9	negative selection	6506688
45455860	45455883	21	+	27260156	CORL105	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.18391614438438542	[704]	[1020,787,1078,889]	3	hSpCas9	negative selection	6506689
45405412	45405435	21	+	27260156	CORL105	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.3937297424485816	[604]	[1100,653,1120,886]	7	hSpCas9	negative selection	6570959
45456061	45456084	21	+	27260156	HS294T	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.8243571413329354	[214]	[28,33,53,77]	-8	hSpCas9	negative selection	6627939
45455860	45455883	21	+	27260156	HS294T	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.4537069583949346	[704]	[420,300,243,553]	6	hSpCas9	negative selection	6627940
45405412	45405435	21	+	27260156	HS294T	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.4563536640049112	[604]	[230,355,443,246]	6	hSpCas9	negative selection	6692210
45456061	45456084	21	+	27260156	HCC44	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.45987083182874966	[214]	[111,132,168,286]	-6	hSpCas9	negative selection	6749190
45455860	45455883	21	+	27260156	HCC44	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.05115538123664898	[704]	[814,636,1023,879]	0	hSpCas9	negative selection	6749191
45405412	45405435	21	+	27260156	HCC44	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.3263662134857024	[604]	[1057,678,897,840]	5	hSpCas9	negative selection	6813461
45456061	45456084	21	+	27260156	G402	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.32685080295582125	[214]	[139,266,229,192]	-4	hSpCas9	negative selection	6870441
45455860	45455883	21	+	27260156	G402	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.008861965261594218	[704]	[1159,947,777,592]	0	hSpCas9	negative selection	6870442
45405412	45405435	21	+	27260156	G402	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.4791481551679554	[604]	[891,877,1336,978]	6	hSpCas9	negative selection	6934712
45456061	45456084	21	+	27260156	L33	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.19572755853136303	[214]	[134,95,141,390]	4	hSpCas9	negative selection	6991692
45455860	45455883	21	+	27260156	L33	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.2346717083550961	[704]	[891,365,491,748]	5	hSpCas9	negative selection	6991693
45405412	45405435	21	+	27260156	L33	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.285381326161086	[604]	[734,310,423,779]	6	hSpCas9	negative selection	7055963
45456061	45456084	21	+	27260156	K562	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.064694030503325	[214]	[205,92,327,107]	-1	hSpCas9	negative selection	7112943
45455860	45455883	21	+	27260156	K562	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.5697152652328378	[704]	[554,428,406,316]	-6	hSpCas9	negative selection	7112944
45405412	45405435	21	+	27260156	K562	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.05236764620583462	[604]	[507,526,494,674]	0	hSpCas9	negative selection	7177214
45456061	45456084	21	+	27260156	HT29	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.4411495416691975	[214]	[253,123,174,211]	-7	hSpCas9	negative selection	7234194
45455860	45455883	21	+	27260156	HT29	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.07889695741947789	[704]	[1105,787,833,892]	1	hSpCas9	negative selection	7234195
45405412	45405435	21	+	27260156	HT29	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.4693487260883744	[604]	[1219,1183,904,811]	8	hSpCas9	negative selection	7298465
45456061	45456084	21	+	27260156	MHHES1	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.13149621726975758	[214]	[275,194,135,264]	-2	hSpCas9	negative selection	7355445
45455860	45455883	21	+	27260156	MHHES1	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.07318399629231787	[704]	[866,696,696,748]	-1	hSpCas9	negative selection	7355446
45405412	45405435	21	+	27260156	MHHES1	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.1616464267912343	[604]	[1103,836,635,551]	3	hSpCas9	negative selection	7419716
45456061	45456084	21	+	27260156	MEWO	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.21864980430416026	[214]	[325,222,170]	5	hSpCas9	negative selection	7476696
45455860	45455883	21	+	27260156	MEWO	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.023166040959385792	[704]	[918,514,565]	0	hSpCas9	negative selection	7476697
45405412	45405435	21	+	27260156	MEWO	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.32724913564094915	[604]	[819,817,512]	7	hSpCas9	negative selection	7540967
45456061	45456084	21	+	27260156	LNCAPCLONEFGC	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.029369411907483434	[214]	[236,201,186,134]	0	hSpCas9	negative selection	7597947
45455860	45455883	21	+	27260156	LNCAPCLONEFGC	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.04723957396514522	[704]	[489,759,766,469]	0	hSpCas9	negative selection	7597948
45405412	45405435	21	+	27260156	LNCAPCLONEFGC	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.1849142749220143	[604]	[635,510,732,634]	3	hSpCas9	negative selection	7662218
45456061	45456084	21	+	27260156	PANC0327	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.06945438994641862	[214]	[425,138,166,95]	1	hSpCas9	negative selection	7719198
45455860	45455883	21	+	27260156	PANC0327	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.4518117011330828	[704]	[498,503,1396,1042]	6	hSpCas9	negative selection	7719199
45405412	45405435	21	+	27260156	PANC0327	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.30835481596398784	[604]	[800,561,561,760]	4	hSpCas9	negative selection	7783469
45456061	45456084	21	+	27260156	NCIH2009	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.22482443444999256	[214]	[420,260,385]	3	hSpCas9	negative selection	7840449
45455860	45455883	21	+	27260156	NCIH2009	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.28314668094614104	[704]	[1662,951,1074]	4	hSpCas9	negative selection	7840450
45405412	45405435	21	+	27260156	NCIH2009	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.5514938139602327	[604]	[1540,1081,1153]	7	hSpCas9	negative selection	7904720
45456061	45456084	21	+	27260156	NCIH1373	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.1021385002053361	[214]	[413,49,120,134]	1	hSpCas9	negative selection	7961700
45455860	45455883	21	+	27260156	NCIH1373	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.04210265607975283	[704]	[794,668,674,250]	0	hSpCas9	negative selection	7961701
45405412	45405435	21	+	27260156	NCIH1373	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.5786550406973652	[604]	[1249,1041,674,295]	6	hSpCas9	negative selection	8025971
45456061	45456084	21	+	27260156	PATU8902	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.24885399870405467	[214]	[227,264,367,584]	2	hSpCas9	negative selection	8082951
45455860	45455883	21	+	27260156	PATU8902	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.3209409337644682	[704]	[1486,1464,731,1352]	3	hSpCas9	negative selection	8082952
45405412	45405435	21	+	27260156	PATU8902	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.8815094281581375	[604]	[1460,1603,1340,1886]	8	hSpCas9	negative selection	8147222
45456061	45456084	21	+	27260156	PANC1	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.4096245914259411	[214]	[74,121,253,106]	-6	hSpCas9	negative selection	8204202
45455860	45455883	21	+	27260156	PANC1	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.11098854503272482	[704]	[617,675,647,665]	1	hSpCas9	negative selection	8204203
45405412	45405435	21	+	27260156	PANC1	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	-0.06275883393181775	[604]	[396,659,673,317]	-1	hSpCas9	negative selection	8268473
45456061	45456084	21	+	27260156	PANC0813	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.044772159637730846	[214]	[288,229,323,145]	0	hSpCas9	negative selection	8325453
45455860	45455883	21	+	27260156	PANC0813	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.025827934397941177	[704]	[941,870,783,785]	0	hSpCas9	negative selection	8325454
45405412	45405435	21	+	27260156	PANC0813	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.2940404639492652	[604]	[883,778,857,958]	5	hSpCas9	negative selection	8389724
45456061	45456084	21	+	27260156	RDES	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.35007186940641044	[214]	[143,176,253,212]	-5	hSpCas9	negative selection	8446704
45455860	45455883	21	+	27260156	RDES	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.021379471473973344	[704]	[740,792,760,900]	0	hSpCas9	negative selection	8446705
45405412	45405435	21	+	27260156	RDES	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.47899214741287865	[604]	[851,800,1214,1042]	7	hSpCas9	negative selection	8510975
45456061	45456084	21	+	27260156	PC3	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.6565121696738179	[214]	[144,118,123,125]	-9	hSpCas9	negative selection	8567955
45455860	45455883	21	+	27260156	PC3	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.19665748421866114	[704]	[646,519,1328,923]	4	hSpCas9	negative selection	8567956
45405412	45405435	21	+	27260156	PC3	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.4454775380498852	[604]	[597,1055,1188,563]	8	hSpCas9	negative selection	8632226
45456061	45456084	21	+	27260156	PATU8988T	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.2502626543573534	[214]	[157,156,260,114]	-4	hSpCas9	negative selection	8689206
45455860	45455883	21	+	27260156	PATU8988T	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.2520492725129102	[704]	[950,838,617,844]	4	hSpCas9	negative selection	8689207
45405412	45405435	21	+	27260156	PATU8988T	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.4644016004383863	[604]	[743,748,883,845]	7	hSpCas9	negative selection	8753477
45456061	45456084	21	+	27260156	T47D	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.12060471182113108	[214]	[283,256,326,219]	2	hSpCas9	negative selection	8810457
45455860	45455883	21	+	27260156	T47D	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.16530717965933628	[704]	[832,970,923,951]	3	hSpCas9	negative selection	8810458
45405412	45405435	21	+	27260156	T47D	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.27048714750289904	[604]	[787,812,924,876]	6	hSpCas9	negative selection	8874728
45456061	45456084	21	+	27260156	SU8686	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.12128201187130871	[214]	[207,225,276,216]	2	hSpCas9	negative selection	8931708
45455860	45455883	21	+	27260156	SU8686	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.22910224383808364	[704]	[672,800,852,991]	4	hSpCas9	negative selection	8931709
45405412	45405435	21	+	27260156	SU8686	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.5349723117118557	[604]	[898,671,878,1075]	8	hSpCas9	negative selection	8995979
45456061	45456084	21	+	27260156	SKES1	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.48566448502976955	[214]	[243,115,139,122]	-8	hSpCas9	negative selection	9052959
45455860	45455883	21	+	27260156	SKES1	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.04201771653786979	[704]	[908,795,560,665]	0	hSpCas9	negative selection	9052960
45405412	45405435	21	+	27260156	SKES1	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.34030340719052443	[604]	[736,1141,741,500]	7	hSpCas9	negative selection	9117230
45456061	45456084	21	+	27260156	TOV112D	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.1650015123312768	[214]	[399,146,296,114]	3	hSpCas9	negative selection	9174210
45455860	45455883	21	+	27260156	TOV112D	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	0.12446539967322501	[704]	[847,856,860,545]	2	hSpCas9	negative selection	9174211
45405412	45405435	21	+	27260156	TOV112D	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.4158135682513534	[604]	[877,765,647,931]	7	hSpCas9	negative selection	9238481
45456061	45456084	21	+	27260156	TC71	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	-0.127311975772326	[214]	[194,235,168,247]	-3	hSpCas9	negative selection	9295461
45455860	45455883	21	+	27260156	TC71	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.04709781999983653	[704]	[739,663,754,767]	-1	hSpCas9	negative selection	9295462
45405412	45405435	21	+	27260156	TC71	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.15232087732911603	[604]	[671,783,681,748]	4	hSpCas9	negative selection	9359732
45456061	45456084	21	+	27260156	TC32	viability	TCCGGGCGCCCACACAACCGAGG	COL18A1	ENSG00000182871	0.15736101873121278	[214]	[189,170,383,193]	3	hSpCas9	negative selection	9416712
45455860	45455883	21	+	27260156	TC32	viability	CGGAGCCGAGATCCTGAACGTGG	COL18A1	ENSG00000182871	-0.12199221811319888	[704]	[612,348,890,699]	-2	hSpCas9	negative selection	9416713
45405412	45405435	21	+	27260156	TC32	viability	CCTGGACGTGCTCGCGCCCCTGG	COL18A1	ENSG00000182871	0.26605348439360077	[604]	[483,397,1089,945]	5	hSpCas9	negative selection	9480983
45405459	45405482	21	-	27869803	HPAFII	viability after 27 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-0.20033702054503344	[89]	[74,12,NaN]	-1	hSpCas9	negative selection	9579597
45455724	45455747	21	-	27869803	HPAFII	viability after 27 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.24915823265733167	[409]	[308,74,NaN]	-2	hSpCas9	negative selection	9579598
45468424	45468447	21	+	27869803	HPAFII	viability after 27 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.08646075300744993	[448]	[314,196,NaN]	0	hSpCas9	negative selection	9579599
45473903	45473926	21	+	27869803	HPAFII	viability after 27 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.7594068794478633	[289]	[352,178,NaN]	6	hSpCas9	negative selection	9579600
45475477	45475500	21	+	27869803	HPAFII	viability after 27 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.2567671952144247	[154]	[158,45,NaN]	2	hSpCas9	negative selection	9579601
45478333	45478356	21	-	27869803	HPAFII	viability after 27 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.010676070139165938	[91]	[45,50,NaN]	0	hSpCas9	negative selection	9579602
45405459	45405482	21	-	27869803	HPAFII	viability after 15 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-0.4497107691320681	[89]	[121,38,NaN]	-5	hSpCas9	negative selection	9662046
45455724	45455747	21	-	27869803	HPAFII	viability after 15 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.23501367374376575	[409]	[559,258,NaN]	-3	hSpCas9	negative selection	9662047
45468424	45468447	21	+	27869803	HPAFII	viability after 15 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.09433302694853163	[448]	[627,444,NaN]	1	hSpCas9	negative selection	9662048
45473903	45473926	21	+	27869803	HPAFII	viability after 15 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.5480113196195981	[289]	[652,332,NaN]	6	hSpCas9	negative selection	9662049
45475477	45475500	21	+	27869803	HPAFII	viability after 15 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.3965261544470957	[154]	[349,137,NaN]	4	hSpCas9	negative selection	9662050
45478333	45478356	21	-	27869803	HPAFII	viability after 15 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.5668377891770221	[91]	[262,73,NaN]	6	hSpCas9	negative selection	9662051
45405459	45405482	21	-	27869803	ASPC1	viability after 36 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.6333042138171808	[251]	[183,4,205]	6	hSpCas9	negative selection	9744495
45455724	45455747	21	-	27869803	ASPC1	viability after 36 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	0.18352738161419446	[906]	[296,372,388]	1	hSpCas9	negative selection	9744496
45468424	45468447	21	+	27869803	ASPC1	viability after 36 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	-0.1090421722192022	[1159]	[479,226,415]	-1	hSpCas9	negative selection	9744497
45473903	45473926	21	+	27869803	ASPC1	viability after 36 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	-0.16457518231418578	[611]	[331,209,73]	-2	hSpCas9	negative selection	9744498
45475477	45475500	21	+	27869803	ASPC1	viability after 36 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.5955694500249513	[475]	[563,27,205]	6	hSpCas9	negative selection	9744499
45478333	45478356	21	-	27869803	ASPC1	viability after 36 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	0.7943428233788448	[359]	[507,231,0]	7	hSpCas9	negative selection	9744500
45405459	45405482	21	-	27869803	PATU8988S	viability after 35 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.19883187017301207	[226]	[75,133,NaN]	2	hSpCas9	negative selection	9826944
45455724	45455747	21	-	27869803	PATU8988S	viability after 35 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.4037800592602862	[952]	[342,236,NaN]	-4	hSpCas9	negative selection	9826945
45468424	45468447	21	+	27869803	PATU8988S	viability after 35 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.5636571677279391	[955]	[602,534,NaN]	6	hSpCas9	negative selection	9826946
45473903	45473926	21	+	27869803	PATU8988S	viability after 35 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.3143088720844454	[625]	[309,316,NaN]	3	hSpCas9	negative selection	9826947
45475477	45475500	21	+	27869803	PATU8988S	viability after 35 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	-0.49941848434476543	[443]	[124,127,NaN]	-5	hSpCas9	negative selection	9826948
45478333	45478356	21	-	27869803	PATU8988S	viability after 35 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.30917455792931325	[331]	[72,142,NaN]	-3	hSpCas9	negative selection	9826949
45405459	45405482	21	-	27869803	PATU8988S	viability after 31 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.04273124385467564	[226]	[72,118,NaN]	0	hSpCas9	negative selection	9909393
45455724	45455747	21	-	27869803	PATU8988S	viability after 31 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.27205991177274946	[952]	[381,228,NaN]	-3	hSpCas9	negative selection	9909394
45468424	45468447	21	+	27869803	PATU8988S	viability after 31 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.9551902942047367	[955]	[746,728,NaN]	9	hSpCas9	negative selection	9909395
45473903	45473926	21	+	27869803	PATU8988S	viability after 31 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.009073276509835526	[625]	[193,323,NaN]	0	hSpCas9	negative selection	9909396
45475477	45475500	21	+	27869803	PATU8988S	viability after 31 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	-0.6174889495930618	[443]	[99,134,NaN]	-6	hSpCas9	negative selection	9909397
45478333	45478356	21	-	27869803	PATU8988S	viability after 31 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.7947595861450862	[331]	[30,133,NaN]	-7	hSpCas9	negative selection	9909398
45405459	45405482	21	-	27869803	HPAFII	viability after 35 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	0.8094523885214926	[89]	[132,19,NaN]	5	hSpCas9	negative selection	9991842
45455724	45455747	21	-	27869803	HPAFII	viability after 35 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	0.019892024485114068	[409]	[272,139,NaN]	0	hSpCas9	negative selection	9991843
45468424	45468447	21	+	27869803	HPAFII	viability after 35 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.4359502463353587	[448]	[243,378,NaN]	3	hSpCas9	negative selection	9991844
45473903	45473926	21	+	27869803	HPAFII	viability after 35 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.8049388990392626	[289]	[295,211,NaN]	5	hSpCas9	negative selection	9991845
45475477	45475500	21	+	27869803	HPAFII	viability after 35 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.004755743811865165	[154]	[121,29,NaN]	0	hSpCas9	negative selection	9991846
45478333	45478356	21	-	27869803	HPAFII	viability after 35 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-1.6571882380449858	[91]	[18,9,NaN]	-7	hSpCas9	negative selection	9991847
45405459	45405482	21	-	27869803	HPAFII	viability after 31 days	GGTCTTACCTGGCTCCGCGGAGG	COL18A1	ENSG00000182871	-0.26984952068351253	[89]	[72,7,NaN]	-2	hSpCas9	negative selection	10074291
45455724	45455747	21	-	27869803	HPAFII	viability after 31 days	CTCTGTGGAACCATTCCGGGGGG	COL18A1	ENSG00000182871	-0.06470234631783311	[409]	[342,85,NaN]	0	hSpCas9	negative selection	10074292
45468424	45468447	21	+	27869803	HPAFII	viability after 31 days	CACATCCGGCCAGCCACAGAGGG	COL18A1	ENSG00000182871	0.32096034978233756	[448]	[264,368,NaN]	2	hSpCas9	negative selection	10074293
45473903	45473926	21	+	27869803	HPAFII	viability after 31 days	CGCTGAGCTGAAGGTGCGCAGGG	COL18A1	ENSG00000182871	0.7264942630241925	[289]	[286,249,NaN]	5	hSpCas9	negative selection	10074294
45475477	45475500	21	+	27869803	HPAFII	viability after 31 days	CATCCGGAGACTCTGGCAGCGGG	COL18A1	ENSG00000182871	0.6887363298095873	[154]	[211,61,NaN]	5	hSpCas9	negative selection	10074295
45478333	45478356	21	-	27869803	HPAFII	viability after 31 days	ACCGGCTTTCCGTCTTCACCGGG	COL18A1	ENSG00000182871	-0.16282546157937183	[91]	[59,30,NaN]	-1	hSpCas9	negative selection	10074296
45490842	45490865	21	+	28162770	P31FUJ	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	-0.3128417023394958	[314]	[297]	-3	hSpCas9	negative selection	10136162
45468312	45468335	21	+	28162770	P31FUJ	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.4790724087889972	[173]	[284]	5	hSpCas9	negative selection	10136163
45468389	45468412	21	-	28162770	P31FUJ	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.6146728397580232	[42]	[32]	-5	hSpCas9	negative selection	10136164
45468621	45468644	21	+	28162770	P31FUJ	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.5207829673784032	[209]	[171]	-4	hSpCas9	negative selection	10136165
45475514	45475537	21	+	28162770	P31FUJ	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.6198253275236258	[135]	[103]	-5	hSpCas9	negative selection	10136166
45476446	45476469	21	+	28162770	P31FUJ	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	0.09342602790660903	[66]	[83]	0	hSpCas9	negative selection	10136167
45477936	45477959	21	+	28162770	P31FUJ	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	0.7013098599291643	[111]	[213]	7	hSpCas9	negative selection	10136168
45480498	45480521	21	+	28162770	P31FUJ	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	-0.06679225297544955	[122]	[137]	0	hSpCas9	negative selection	10136169
45480837	45480860	21	-	28162770	P31FUJ	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.6024836503910174	[379]	[677]	7	hSpCas9	negative selection	10136170
45490842	45490865	21	+	28162770	TF1	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10305528
45468312	45468335	21	+	28162770	TF1	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10305529
45468389	45468412	21	-	28162770	TF1	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10305530
45468621	45468644	21	+	28162770	TF1	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10305531
45475514	45475537	21	+	28162770	TF1	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10305532
45476446	45476469	21	+	28162770	TF1	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10305533
45477936	45477959	21	+	28162770	TF1	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10305534
45480498	45480521	21	+	28162770	TF1	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10305535
45480837	45480860	21	-	28162770	TF1	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10305536
45490842	45490865	21	+	28162770	SKM1	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	-0.3416727384914424	[80]	[112]	-3	hSpCas9	negative selection	10474894
45468312	45468335	21	+	28162770	SKM1	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	1.1198953474144262	[37]	[145]	9	hSpCas9	negative selection	10474895
45468389	45468412	21	-	28162770	SKM1	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.76953427812787	[26]	[27]	-5	hSpCas9	negative selection	10474896
45468621	45468644	21	+	28162770	SKM1	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.7931754157461584	[62]	[192]	7	hSpCas9	negative selection	10474897
45475514	45475537	21	+	28162770	SKM1	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.16080361147376415	[42]	[67]	-1	hSpCas9	negative selection	10474898
45476446	45476469	21	+	28162770	SKM1	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-0.6699986045769557	[8]	[9]	-5	hSpCas9	negative selection	10474899
45477936	45477959	21	+	28162770	SKM1	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.008414822252886811	[32]	[57]	0	hSpCas9	negative selection	10474900
45480498	45480521	21	+	28162770	SKM1	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	0.4999263968653569	[15]	[39]	5	hSpCas9	negative selection	10474901
45480837	45480860	21	-	28162770	SKM1	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.17799830197799443	[62]	[125]	1	hSpCas9	negative selection	10474902
45490842	45490865	21	+	28162770	SKM1	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	-0.3416727384914424	[80]	[112]	-3	hSpCas9	negative selection	10644260
45468312	45468335	21	+	28162770	SKM1	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	1.1198953474144262	[37]	[145]	9	hSpCas9	negative selection	10644261
45468389	45468412	21	-	28162770	SKM1	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.76953427812787	[26]	[27]	-5	hSpCas9	negative selection	10644262
45468621	45468644	21	+	28162770	SKM1	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.7931754157461584	[62]	[192]	7	hSpCas9	negative selection	10644263
45475514	45475537	21	+	28162770	SKM1	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.16080361147376415	[42]	[67]	-1	hSpCas9	negative selection	10644264
45476446	45476469	21	+	28162770	SKM1	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-0.6699986045769557	[8]	[9]	-5	hSpCas9	negative selection	10644265
45477936	45477959	21	+	28162770	SKM1	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.008414822252886811	[32]	[57]	0	hSpCas9	negative selection	10644266
45480498	45480521	21	+	28162770	SKM1	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	0.4999263968653569	[15]	[39]	5	hSpCas9	negative selection	10644267
45480837	45480860	21	-	28162770	SKM1	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.17799830197799443	[62]	[125]	1	hSpCas9	negative selection	10644268
45490842	45490865	21	+	28162770	PL21	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.33937541186049236	[226]	[124]	3	hSpCas9	negative selection	10813626
45468312	45468335	21	+	28162770	PL21	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.2751016721705422	[149]	[78]	2	hSpCas9	negative selection	10813627
45468389	45468412	21	-	28162770	PL21	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-2.8442545048691334	[98]	[5]	-9	hSpCas9	negative selection	10813628
45468621	45468644	21	+	28162770	PL21	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.00891521124655148	[289]	[126]	0	hSpCas9	negative selection	10813629
45475514	45475537	21	+	28162770	PL21	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	1.56429594476598	[100]	[129]	9	hSpCas9	negative selection	10813630
45476446	45476469	21	+	28162770	PL21	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	0.6151771137681639	[29]	[19]	5	hSpCas9	negative selection	10813631
45477936	45477959	21	+	28162770	PL21	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.009313751139629733	[73]	[31]	0	hSpCas9	negative selection	10813632
45480498	45480521	21	+	28162770	PL21	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	-2.4292170055902895	[98]	[7]	-9	hSpCas9	negative selection	10813633
45480837	45480860	21	-	28162770	PL21	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	-0.19516166672826138	[241]	[91]	-1	hSpCas9	negative selection	10813634
45490842	45490865	21	+	28162770	P31FUJ	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	-0.3128417023394958	[314]	[297]	-3	hSpCas9	negative selection	10982992
45468312	45468335	21	+	28162770	P31FUJ	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.4790724087889972	[173]	[284]	5	hSpCas9	negative selection	10982993
45468389	45468412	21	-	28162770	P31FUJ	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.6146728397580232	[42]	[32]	-5	hSpCas9	negative selection	10982994
45468621	45468644	21	+	28162770	P31FUJ	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.5207829673784032	[209]	[171]	-4	hSpCas9	negative selection	10982995
45475514	45475537	21	+	28162770	P31FUJ	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.6198253275236258	[135]	[103]	-5	hSpCas9	negative selection	10982996
45476446	45476469	21	+	28162770	P31FUJ	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	0.09342602790660903	[66]	[83]	0	hSpCas9	negative selection	10982997
45477936	45477959	21	+	28162770	P31FUJ	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	0.7013098599291643	[111]	[213]	7	hSpCas9	negative selection	10982998
45480498	45480521	21	+	28162770	P31FUJ	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	-0.06679225297544955	[122]	[137]	0	hSpCas9	negative selection	10982999
45480837	45480860	21	-	28162770	P31FUJ	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.6024836503910174	[379]	[677]	7	hSpCas9	negative selection	10983000
45490842	45490865	21	+	28162770	OCIAML5	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.5748310836249078	[105]	[284]	5	hSpCas9	negative selection	11152358
45468312	45468335	21	+	28162770	OCIAML5	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.19057776654449654	[49]	[102]	1	hSpCas9	negative selection	11152359
45468389	45468412	21	-	28162770	OCIAML5	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-1.795483042497629	[24]	[12]	-7	hSpCas9	negative selection	11152360
45468621	45468644	21	+	28162770	OCIAML5	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.13175221724795458	[121]	[200]	-1	hSpCas9	negative selection	11152361
45475514	45475537	21	+	28162770	OCIAML5	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.8557526776426927	[59]	[195]	7	hSpCas9	negative selection	11152362
45476446	45476469	21	+	28162770	OCIAML5	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	0.619239148061592	[21]	[60]	5	hSpCas9	negative selection	11152363
45477936	45477959	21	+	28162770	OCIAML5	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	0.7234356006080929	[50]	[151]	6	hSpCas9	negative selection	11152364
45480498	45480521	21	+	28162770	OCIAML5	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	1.8390953336890843	[23]	[154]	9	hSpCas9	negative selection	11152365
45480837	45480860	21	-	28162770	OCIAML5	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	-0.34377966088167	[160]	[228]	-2	hSpCas9	negative selection	11152366
45490842	45490865	21	+	28162770	EOL1	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.6521755011574044	[278]	[230]	6	hSpCas9	negative selection	11321724
45468312	45468335	21	+	28162770	EOL1	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	-0.3065513451168125	[276]	[117]	-2	hSpCas9	negative selection	11321725
45468389	45468412	21	-	28162770	EOL1	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.5514803575974577	[152]	[54]	-4	hSpCas9	negative selection	11321726
45468621	45468644	21	+	28162770	EOL1	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-1.0781413159571054	[536]	[133]	-6	hSpCas9	negative selection	11321727
45475514	45475537	21	+	28162770	EOL1	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.8828071504870694	[216]	[61]	-6	hSpCas9	negative selection	11321728
45476446	45476469	21	+	28162770	EOL1	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	1.5959250241091638	[26]	[42]	9	hSpCas9	negative selection	11321729
45477936	45477959	21	+	28162770	EOL1	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-1.8334794381235011	[114]	[16]	-8	hSpCas9	negative selection	11321730
45480498	45480521	21	+	28162770	EOL1	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	-0.43390619934194197	[99]	[38]	-3	hSpCas9	negative selection	11321731
45480837	45480860	21	-	28162770	EOL1	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	-0.9156717843926963	[332]	[92]	-6	hSpCas9	negative selection	11321732
45490842	45490865	21	+	28162770	MOLM13	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	-0.11500770001079325	[348]	[232]	0	hSpCas9	negative selection	11491090
45468312	45468335	21	+	28162770	MOLM13	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	1.506658951709154	[256]	[527]	9	hSpCas9	negative selection	11491091
45468389	45468412	21	-	28162770	MOLM13	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.7139489414412344	[151]	[66]	-4	hSpCas9	negative selection	11491092
45468621	45468644	21	+	28162770	MOLM13	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.4806755365004222	[336]	[339]	3	hSpCas9	negative selection	11491093
45475514	45475537	21	+	28162770	MOLM13	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.9320537382945981	[165]	[228]	7	hSpCas9	negative selection	11491094
45476446	45476469	21	+	28162770	MOLM13	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	1.1142524269298781	[45]	[71]	8	hSpCas9	negative selection	11491095
45477936	45477959	21	+	28162770	MOLM13	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	0.38108455400730623	[136]	[128]	2	hSpCas9	negative selection	11491096
45480498	45480521	21	+	28162770	MOLM13	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	0.6793934867382905	[75]	[87]	5	hSpCas9	negative selection	11491097
45480837	45480860	21	-	28162770	MOLM13	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.5273432317548213	[308]	[321]	4	hSpCas9	negative selection	11491098
45490842	45490865	21	+	28162770	HEL	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.03297294027862835	[263]	[172]	0	hSpCas9	negative selection	11660456
45468312	45468335	21	+	28162770	HEL	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.5331143408258588	[204]	[189]	4	hSpCas9	negative selection	11660457
45468389	45468412	21	-	28162770	HEL	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	0.2969639951586269	[121]	[95]	2	hSpCas9	negative selection	11660458
45468621	45468644	21	+	28162770	HEL	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.10101592782848845	[354]	[211]	0	hSpCas9	negative selection	11660459
45475514	45475537	21	+	28162770	HEL	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.8512500086733089	[168]	[59]	-5	hSpCas9	negative selection	11660460
45476446	45476469	21	+	28162770	HEL	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-1.1386208815243024	[54]	[15]	-6	hSpCas9	negative selection	11660461
45477936	45477959	21	+	28162770	HEL	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.8718343408294011	[119]	[41]	-5	hSpCas9	negative selection	11660462
45480498	45480521	21	+	28162770	HEL	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	1.3336347774705781	[69]	[112]	9	hSpCas9	negative selection	11660463
45480837	45480860	21	-	28162770	HEL	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	-0.18598974084981423	[237]	[133]	-1	hSpCas9	negative selection	11660464
45490842	45490865	21	+	28162770	MV411	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	0.07659684315872801	[196]	[174]	0	hSpCas9	negative selection	11829822
45468312	45468335	21	+	28162770	MV411	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.21067900077265758	[158]	[154]	1	hSpCas9	negative selection	11829823
45468389	45468412	21	-	28162770	MV411	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.1770602777451351	[50]	[37]	-1	hSpCas9	negative selection	11829824
45468621	45468644	21	+	28162770	MV411	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.48737315867975695	[222]	[133]	-4	hSpCas9	negative selection	11829825
45475514	45475537	21	+	28162770	MV411	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.8900659729671595	[142]	[64]	-6	hSpCas9	negative selection	11829826
45476446	45476469	21	+	28162770	MV411	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-1.5301700278807773	[23]	[6]	-7	hSpCas9	negative selection	11829827
45477936	45477959	21	+	28162770	MV411	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.021379207645024434	[99]	[82]	0	hSpCas9	negative selection	11829828
45480498	45480521	21	+	28162770	MV411	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	-0.074490544104587	[94]	[75]	0	hSpCas9	negative selection	11829829
45480837	45480860	21	-	28162770	MV411	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	-0.7581006327586546	[260]	[129]	-5	hSpCas9	negative selection	11829830
45490842	45490865	21	+	28162770	MONOMAC1	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	1.0770397295658252	[140]	[340]	8	hSpCas9	negative selection	11999188
45468312	45468335	21	+	28162770	MONOMAC1	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	1.0298781329675883	[90]	[212]	8	hSpCas9	negative selection	11999189
45468389	45468412	21	-	28162770	MONOMAC1	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	-0.6244580707942298	[38]	[28]	-5	hSpCas9	negative selection	11999190
45468621	45468644	21	+	28162770	MONOMAC1	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.33347786963922593	[161]	[233]	3	hSpCas9	negative selection	11999191
45475514	45475537	21	+	28162770	MONOMAC1	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	-0.4253058347326708	[81]	[69]	-4	hSpCas9	negative selection	11999192
45476446	45476469	21	+	28162770	MONOMAC1	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-0.039495570073073694	[25]	[28]	0	hSpCas9	negative selection	11999193
45477936	45477959	21	+	28162770	MONOMAC1	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	1.1297734692075547	[58]	[147]	8	hSpCas9	negative selection	11999194
45480498	45480521	21	+	28162770	MONOMAC1	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	-0.5869833653755672	[37]	[28]	-5	hSpCas9	negative selection	11999195
45480837	45480860	21	-	28162770	MONOMAC1	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.9841329115503811	[141]	[321]	8	hSpCas9	negative selection	11999196
45490842	45490865	21	+	28162770	OCIAML2	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	-0.32585830102818736	[44]	[198]	-3	hSpCas9	negative selection	12168554
45468312	45468335	21	+	28162770	OCIAML2	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	-0.4706298252421612	[26]	[107]	-4	hSpCas9	negative selection	12168555
45468389	45468412	21	-	28162770	OCIAML2	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	0.15085855150410876	[12]	[79]	1	hSpCas9	negative selection	12168556
45468621	45468644	21	+	28162770	OCIAML2	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	0.7794655248841343	[34]	[332]	7	hSpCas9	negative selection	12168557
45475514	45475537	21	+	28162770	OCIAML2	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.024134866507416697	[21]	[123]	0	hSpCas9	negative selection	12168558
45476446	45476469	21	+	28162770	OCIAML2	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-0.11307782062407767	[7]	[40]	-1	hSpCas9	negative selection	12168559
45477936	45477959	21	+	28162770	OCIAML2	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.996698636909749	[17]	[49]	-6	hSpCas9	negative selection	12168560
45480498	45480521	21	+	28162770	OCIAML2	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	0.3537986101743844	[11]	[84]	3	hSpCas9	negative selection	12168561
45480837	45480860	21	-	28162770	OCIAML2	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	0.4305920202796652	[33]	[253]	4	hSpCas9	negative selection	12168562
45490842	45490865	21	+	28162770	OCIAML3	viability	AAGGGAGACAGAGGCAGCCGGGG	COL18A1	ENSG00000182871	-0.11827420935776528	[63]	[177]	-1	hSpCas9	negative selection	12337920
45468312	45468335	21	+	28162770	OCIAML3	viability	GGATGACCCCGACGTCGGGCTGG	COL18A1	ENSG00000182871	0.7763608096209522	[40]	[211]	7	hSpCas9	negative selection	12337921
45468389	45468412	21	-	28162770	OCIAML3	viability	GAAGTCACGGAAGAAGAGGCTGG	COL18A1	ENSG00000182871	0.24926685598838372	[16]	[60]	2	hSpCas9	negative selection	12337922
45468621	45468644	21	+	28162770	OCIAML3	viability	GACACACTTAGCCCTCAGTGTGG	COL18A1	ENSG00000182871	-0.14775141043459927	[79]	[217]	-1	hSpCas9	negative selection	12337923
45475514	45475537	21	+	28162770	OCIAML3	viability	GGAGCTTCTCAGGGAGGAGACGG	COL18A1	ENSG00000182871	0.7279204545631993	[36]	[184]	6	hSpCas9	negative selection	12337924
45476446	45476469	21	+	28162770	OCIAML3	viability	AGTCGAGGAGCAGACCACGGTGG	COL18A1	ENSG00000182871	-0.9419309437444698	[6]	[10]	-6	hSpCas9	negative selection	12337925
45477936	45477959	21	+	28162770	OCIAML3	viability	GACGGCACCCCTGGAAGGGACGG	COL18A1	ENSG00000182871	-0.2628017318487901	[30]	[77]	-2	hSpCas9	negative selection	12337926
45480498	45480521	21	+	28162770	OCIAML3	viability	GGGGCGATCTGGAGGCCCTGCGG	COL18A1	ENSG00000182871	-1.9565777197088716	[17]	[13]	-8	hSpCas9	negative selection	12337927
45480837	45480860	21	-	28162770	OCIAML3	viability	CCGGGAGGCCAGGAAACCCGGGG	COL18A1	ENSG00000182871	-0.06763979351385507	[66]	[192]	0	hSpCas9	negative selection	12337928