Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1311
• Symbol:COMP
• Description:cartilage oligomeric matrix protein

DataSource: http://genomecrispr.dkfz.de/#!/results/COMP

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18791234	18791257	19	+	26472758	Jiyoye	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	0.19519957611476385	[160]	[138]	1	hSpCas9	negative selection	35535
18786082	18786105	19	-	26472758	Jiyoye	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.8799283786410046	[48]	[67]	6	hSpCas9	negative selection	35536
18790885	18790908	19	-	26472758	Jiyoye	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	5.451569500864326	[0]	[32]	9	hSpCas9	negative selection	35537
18790074	18790097	19	-	26472758	Jiyoye	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	1.1105583751476986	[112]	[183]	7	hSpCas9	negative selection	35538
18789244	18789267	19	-	26472758	Jiyoye	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.4274953658854692	[140]	[142]	3	hSpCas9	negative selection	35539
18788286	18788309	19	-	26472758	Jiyoye	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.24081699508375334	[100]	[89]	1	hSpCas9	negative selection	35540
18788267	18788290	19	-	26472758	Jiyoye	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.06234688450843227	[126]	[99]	0	hSpCas9	negative selection	35541
18787523	18787546	19	-	26472758	Jiyoye	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.09571428566957974	[102]	[82]	0	hSpCas9	negative selection	35542
18786581	18786604	19	-	26472758	Jiyoye	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	-1.4494604433229494	[133]	[36]	-7	hSpCas9	negative selection	35543
18786258	18786281	19	+	26472758	Jiyoye	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	5.051031571280598	[0]	[24]	9	hSpCas9	negative selection	35544
18791234	18791257	19	+	26472758	KBM7	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.09762243195004539	[720,521]	[232,302]	-1	hSpCas9	negative selection	226653
18786082	18786105	19	-	26472758	KBM7	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.15176090799420472	[338,243]	[169,132]	1	hSpCas9	negative selection	226654
18790885	18790908	19	-	26472758	KBM7	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.9887071916712608	[215,158]	[114,224]	9	hSpCas9	negative selection	226655
18790074	18790097	19	-	26472758	KBM7	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.14117991587027134	[943,960]	[425,559]	1	hSpCas9	negative selection	226656
18789244	18789267	19	-	26472758	KBM7	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.6053714650066016	[584,348]	[344,310]	6	hSpCas9	negative selection	226657
18788286	18788309	19	-	26472758	KBM7	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.7339579762489493	[455,425]	[234,443]	7	hSpCas9	negative selection	226658
18788267	18788290	19	-	26472758	KBM7	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.13406018872929393	[779,708]	[356,284]	-1	hSpCas9	negative selection	226659
18787523	18787546	19	-	26472758	KBM7	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.6680723619505184	[573,347]	[309,361]	7	hSpCas9	negative selection	226660
18786581	18786604	19	-	26472758	KBM7	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.11318025985702473	[374,315]	[98,242]	1	hSpCas9	negative selection	226661
18786258	18786281	19	+	26472758	KBM7	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-1.432150654451492	[55,239]	[35,19]	-7	hSpCas9	negative selection	226662
18791234	18791257	19	+	26472758	Raji	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	0.13909239510093765	[269]	[68]	1	hSpCas9	negative selection	417771
18786082	18786105	19	-	26472758	Raji	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.4498339748646525	[205]	[34]	-4	hSpCas9	negative selection	417772
18790885	18790908	19	-	26472758	Raji	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	-1.140543978069986	[75]	[7]	-7	hSpCas9	negative selection	417773
18790074	18790097	19	-	26472758	Raji	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.40694381723250705	[428]	[131]	4	hSpCas9	negative selection	417774
18789244	18789267	19	-	26472758	Raji	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.4378952638750744	[250]	[42]	-4	hSpCas9	negative selection	417775
18788286	18788309	19	-	26472758	Raji	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.4707589148299507	[198]	[63]	4	hSpCas9	negative selection	417776
18788267	18788290	19	-	26472758	Raji	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.12527722141667547	[328]	[69]	-1	hSpCas9	negative selection	417777
18787523	18787546	19	-	26472758	Raji	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.6744241280974932	[188]	[69]	6	hSpCas9	negative selection	417778
18786581	18786604	19	-	26472758	Raji	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.07261811721292294	[167]	[40]	0	hSpCas9	negative selection	417779
18786258	18786281	19	+	26472758	Raji	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	0.9781005184286331	[34]	[15]	8	hSpCas9	negative selection	417780
18791234	18791257	19	+	26472758	K562	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.1652598557737508	[626]	[471]	-1	hSpCas9	negative selection	608889
18786082	18786105	19	-	26472758	K562	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.32091496630577676	[218]	[147]	-2	hSpCas9	negative selection	608890
18790885	18790908	19	-	26472758	K562	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	-0.7459311022998341	[148]	[74]	-4	hSpCas9	negative selection	608891
18790074	18790097	19	-	26472758	K562	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.3573571058198497	[699]	[756]	3	hSpCas9	negative selection	608892
18789244	18789267	19	-	26472758	K562	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.6811788819355318	[358]	[188]	-4	hSpCas9	negative selection	608893
18788286	18788309	19	-	26472758	K562	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.6281017942043535	[406]	[530]	5	hSpCas9	negative selection	608894
18788267	18788290	19	-	26472758	K562	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.1560317335173685	[487]	[458]	1	hSpCas9	negative selection	608895
18787523	18787546	19	-	26472758	K562	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.5083812101104954	[258]	[310]	4	hSpCas9	negative selection	608896
18786581	18786604	19	-	26472758	K562	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.7656166858585106	[238]	[342]	6	hSpCas9	negative selection	608897
18786258	18786281	19	+	26472758	K562	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	0.5040625442994664	[70]	[84]	4	hSpCas9	negative selection	608898
18788463	18788486	19	+	26627737	DLD1	viability	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-0.5757870279299259	[508]	[147,20,141]	-5	hSpCas9	negative selection	803497
18788608	18788631	19	-	26627737	DLD1	viability	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.37617880713802965	[114]	[12,101,29]	4	hSpCas9	negative selection	803498
18788839	18788862	19	-	26627737	DLD1	viability	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.014313908052862034	[668]	[123,252,240]	0	hSpCas9	negative selection	803499
18789246	18789269	19	+	26627737	DLD1	viability	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.5783216165250045	[1436]	[290,380,242]	-5	hSpCas9	negative selection	803500
18790016	18790039	19	-	26627737	DLD1	viability	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.3226097747978045	[252]	[228,176,187]	9	hSpCas9	negative selection	803501
18791176	18791199	19	+	26627737	DLD1	viability	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	1.0662012491553798	[337]	[198,309,166]	8	hSpCas9	negative selection	803502
18788463	18788486	19	+	26627737	GBM cells	viability after 5 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-0.5535983298118211	[181]	[66,65]	-7	hSpCas9	negative selection	885812
18788608	18788631	19	-	26627737	GBM cells	viability after 5 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.009938237056119181	[45]	[33,14]	0	hSpCas9	negative selection	885813
18788839	18788862	19	-	26627737	GBM cells	viability after 5 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.4646828103735309	[226]	[172,162]	7	hSpCas9	negative selection	885814
18789246	18789269	19	+	26627737	GBM cells	viability after 5 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.2803106872943888	[641]	[312,253]	-4	hSpCas9	negative selection	885815
18790016	18790039	19	-	26627737	GBM cells	viability after 5 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.1800357533851622	[250]	[141,162]	3	hSpCas9	negative selection	885816
18791176	18791199	19	+	26627737	GBM cells	viability after 5 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.1636275911830274	[164]	[67,89]	-3	hSpCas9	negative selection	885817
18788463	18788486	19	+	26627737	GBM cells	viability after 13 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	0.046109687318198755	[181]	[80,118]	0	hSpCas9	negative selection	968127
18788608	18788631	19	-	26627737	GBM cells	viability after 13 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.6089789291320225	[45]	[31,42]	7	hSpCas9	negative selection	968128
18788839	18788862	19	-	26627737	GBM cells	viability after 13 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.1932951607658343	[226]	[99,113]	-2	hSpCas9	negative selection	968129
18789246	18789269	19	+	26627737	GBM cells	viability after 13 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.2843808464923756	[641]	[317,259]	-3	hSpCas9	negative selection	968130
18790016	18790039	19	-	26627737	GBM cells	viability after 13 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.6465137293976516	[250]	[237,192]	7	hSpCas9	negative selection	968131
18791176	18791199	19	+	26627737	GBM cells	viability after 13 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.00739825191704957	[164]	[57,115]	0	hSpCas9	negative selection	968132
18788463	18788486	19	+	26627737	GBM cells	viability after 21 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-0.041430462949961555	[181]	[105,86]	0	hSpCas9	negative selection	1050442
18788608	18788631	19	-	26627737	GBM cells	viability after 21 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.0030900474011916756	[45]	[23,25]	0	hSpCas9	negative selection	1050443
18788839	18788862	19	-	26627737	GBM cells	viability after 21 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.3818692694545936	[226]	[102,86]	-3	hSpCas9	negative selection	1050444
18789246	18789269	19	+	26627737	GBM cells	viability after 21 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-1.2641881495525136	[641]	[151,138]	-8	hSpCas9	negative selection	1050445
18790016	18790039	19	-	26627737	GBM cells	viability after 21 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.28777925598458004	[250]	[178,154]	3	hSpCas9	negative selection	1050446
18791176	18791199	19	+	26627737	GBM cells	viability after 21 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.6468534449004051	[164]	[131,147]	6	hSpCas9	negative selection	1050447
18788463	18788486	19	+	26627737	RPE1	viability after 9 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-0.4707770164742989	[868]	[194,197]	-3	hSpCas9	negative selection	1132757
18788608	18788631	19	-	26627737	RPE1	viability after 9 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.41973511580568057	[226]	[53,51]	-3	hSpCas9	negative selection	1132758
18788839	18788862	19	-	26627737	RPE1	viability after 9 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.6920535246327474	[856]	[138,200]	-5	hSpCas9	negative selection	1132759
18789246	18789269	19	+	26627737	RPE1	viability after 9 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.16178357228699425	[3198]	[686,1163]	-1	hSpCas9	negative selection	1132760
18790016	18790039	19	-	26627737	RPE1	viability after 9 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.3542169022542052	[428]	[369,308]	7	hSpCas9	negative selection	1132761
18791176	18791199	19	+	26627737	RPE1	viability after 9 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	1.093999681632435	[380]	[220,297]	6	hSpCas9	negative selection	1132762
18788463	18788486	19	+	26627737	RPE1	viability after 12 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-0.4888370686514091	[868]	[246,80]	-3	hSpCas9	negative selection	1215072
18788608	18788631	19	-	26627737	RPE1	viability after 12 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.5890612185021926	[226]	[41,38]	-4	hSpCas9	negative selection	1215073
18788839	18788862	19	-	26627737	RPE1	viability after 12 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.4036227728970362	[856]	[175,171]	-3	hSpCas9	negative selection	1215074
18789246	18789269	19	+	26627737	RPE1	viability after 12 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.10890967114738181	[3198]	[778,815]	0	hSpCas9	negative selection	1215075
18790016	18790039	19	-	26627737	RPE1	viability after 12 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.1633034429805877	[428]	[211,306]	7	hSpCas9	negative selection	1215076
18791176	18791199	19	+	26627737	RPE1	viability after 12 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	1.073147286899206	[380]	[227,201]	6	hSpCas9	negative selection	1215077
18788463	18788486	19	+	26627737	RPE1	viability after 15 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-1.1766369238182675	[868]	[122,94]	-6	hSpCas9	negative selection	1297387
18788608	18788631	19	-	26627737	RPE1	viability after 15 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.12881056174348227	[226]	[73,43]	-1	hSpCas9	negative selection	1297388
18788839	18788862	19	-	26627737	RPE1	viability after 15 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.18275999286462777	[856]	[208,217]	-1	hSpCas9	negative selection	1297389
18789246	18789269	19	+	26627737	RPE1	viability after 15 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.08614249628157933	[3198]	[881,823]	0	hSpCas9	negative selection	1297390
18790016	18790039	19	-	26627737	RPE1	viability after 15 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	2.0281931573526766	[428]	[466,521]	8	hSpCas9	negative selection	1297391
18791176	18791199	19	+	26627737	RPE1	viability after 15 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	1.246596394006196	[380]	[326,186]	7	hSpCas9	negative selection	1297392
18788463	18788486	19	+	26627737	RPE1	viability after 18 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	0.1757625078977599	[868]	[363,158]	1	hSpCas9	negative selection	1379702
18788608	18788631	19	-	26627737	RPE1	viability after 18 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.5314362551850327	[226]	[38,45]	-3	hSpCas9	negative selection	1379703
18788839	18788862	19	-	26627737	RPE1	viability after 18 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.7572268629411482	[856]	[504,268]	4	hSpCas9	negative selection	1379704
18789246	18789269	19	+	26627737	RPE1	viability after 18 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	0.15301112536800732	[3198]	[927,993]	1	hSpCas9	negative selection	1379705
18790016	18790039	19	-	26627737	RPE1	viability after 18 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.481367422297769	[428]	[286,361]	7	hSpCas9	negative selection	1379706
18791176	18791199	19	+	26627737	RPE1	viability after 18 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.8674787741975157	[380]	[131,246]	5	hSpCas9	negative selection	1379707
18788463	18788486	19	+	26627737	HeLa	viability after 8 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-2.128113323303532	[587]	[45,55,69]	-9	hSpCas9	negative selection	1462017
18788608	18788631	19	-	26627737	HeLa	viability after 8 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.16829610589012045	[63]	[9,44,33]	1	hSpCas9	negative selection	1462018
18788839	18788862	19	-	26627737	HeLa	viability after 8 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.4900870741855602	[415]	[375,195,219]	4	hSpCas9	negative selection	1462019
18789246	18789269	19	+	26627737	HeLa	viability after 8 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.16890389847765452	[1566]	[652,765,423]	-2	hSpCas9	negative selection	1462020
18790016	18790039	19	-	26627737	HeLa	viability after 8 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.7175076214998979	[309]	[225,168,267]	6	hSpCas9	negative selection	1462021
18791176	18791199	19	+	26627737	HeLa	viability after 8 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.47558289634981005	[201]	[95,173,92]	4	hSpCas9	negative selection	1462022
18788463	18788486	19	+	26627737	HeLa	viability after 12 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-1.5283755687138219	[587]	[30,66,154]	-8	hSpCas9	negative selection	1544332
18788608	18788631	19	-	26627737	HeLa	viability after 12 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.816171830395283	[63]	[19,16,7]	-6	hSpCas9	negative selection	1544333
18788839	18788862	19	-	26627737	HeLa	viability after 12 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.10976970604738293	[415]	[132,198,140]	-1	hSpCas9	negative selection	1544334
18789246	18789269	19	+	26627737	HeLa	viability after 12 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.1992355655331992	[1566]	[719,447,540]	-2	hSpCas9	negative selection	1544335
18790016	18790039	19	-	26627737	HeLa	viability after 12 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.4197544389778344	[309]	[176,192,141]	3	hSpCas9	negative selection	1544336
18791176	18791199	19	+	26627737	HeLa	viability after 12 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.6015392769718375	[201]	[213,93,77]	5	hSpCas9	negative selection	1544337
18788463	18788486	19	+	26627737	HeLa	viability after 15 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-2.5439918741882983	[587]	[2,62,58]	-9	hSpCas9	negative selection	1626647
18788608	18788631	19	-	26627737	HeLa	viability after 15 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.3861057380540762	[63]	[27,54,17]	3	hSpCas9	negative selection	1626648
18788839	18788862	19	-	26627737	HeLa	viability after 15 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.23216510269095597	[415]	[53,280,268]	2	hSpCas9	negative selection	1626649
18789246	18789269	19	+	26627737	HeLa	viability after 15 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.2844951683337409	[1566]	[332,580,670]	-2	hSpCas9	negative selection	1626650
18790016	18790039	19	-	26627737	HeLa	viability after 15 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.1033484170910826	[309]	[276,160,383]	7	hSpCas9	negative selection	1626651
18791176	18791199	19	+	26627737	HeLa	viability after 15 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.4989812298453715	[201]	[20,186,143]	4	hSpCas9	negative selection	1626652
18788463	18788486	19	+	26627737	HeLa	viability after 18 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-2.517943685104317	[587]	[1,53,58]	-9	hSpCas9	negative selection	1708962
18788608	18788631	19	-	26627737	HeLa	viability after 18 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.5108115949229113	[63]	[21,48,17]	4	hSpCas9	negative selection	1708963
18788839	18788862	19	-	26627737	HeLa	viability after 18 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.19755399092846598	[415]	[25,233,268]	1	hSpCas9	negative selection	1708964
18789246	18789269	19	+	26627737	HeLa	viability after 18 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.28350212800692653	[1566]	[216,489,670]	-2	hSpCas9	negative selection	1708965
18790016	18790039	19	-	26627737	HeLa	viability after 18 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.0997668269127412	[309]	[183,133,383]	7	hSpCas9	negative selection	1708966
18791176	18791199	19	+	26627737	HeLa	viability after 18 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.5270242402686095	[201]	[15,157,143]	4	hSpCas9	negative selection	1708967
18788463	18788486	19	+	26627737	HCT116	viability after 6 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-1.890013729168757	[515]	[37,12]	-8	hSpCas9	negative selection	1791277
18788608	18788631	19	-	26627737	HCT116	viability after 6 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-4.493511557301928	[327]	[0,2]	-9	hSpCas9	negative selection	1791278
18788839	18788862	19	-	26627737	HCT116	viability after 6 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.6798532010819633	[936]	[652,5]	4	hSpCas9	negative selection	1791279
18789246	18789269	19	+	26627737	HCT116	viability after 6 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	0.8236421959208642	[2169]	[1043,360]	4	hSpCas9	negative selection	1791280
18790016	18790039	19	-	26627737	HCT116	viability after 6 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.1131769312410609	[322]	[250,31]	6	hSpCas9	negative selection	1791281
18791176	18791199	19	+	26627737	HCT116	viability after 6 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	2.5935656297918612	[148]	[103,161]	9	hSpCas9	negative selection	1791282
18788463	18788486	19	+	26627737	HCT116	viability after 8 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	0.7786986663419728	[93]	[124,116,25]	7	hSpCas9	negative selection	1873592
18788608	18788631	19	-	26627737	HCT116	viability after 8 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.3924713648431466	[81]	[57,36,8]	-4	hSpCas9	negative selection	1873593
18788839	18788862	19	-	26627737	HCT116	viability after 8 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.8284674368600302	[124]	[157,121,87]	7	hSpCas9	negative selection	1873594
18789246	18789269	19	+	26627737	HCT116	viability after 8 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.3913350541623697	[1095]	[369,406,600]	-4	hSpCas9	negative selection	1873595
18790016	18790039	19	-	26627737	HCT116	viability after 8 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	-0.08275646531773058	[344]	[111,219,204]	-1	hSpCas9	negative selection	1873596
18791176	18791199	19	+	26627737	HCT116	viability after 8 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.30405541604587005	[174]	[105,137,112]	3	hSpCas9	negative selection	1873597
18788463	18788486	19	+	26627737	HCT116	viability after 9 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	0.0752841964567986	[515]	[300,21]	0	hSpCas9	negative selection	1955907
18788608	18788631	19	-	26627737	HCT116	viability after 9 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.8741129995021334	[327]	[25,64]	-6	hSpCas9	negative selection	1955908
18788839	18788862	19	-	26627737	HCT116	viability after 9 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.17654491291894198	[936]	[274,178]	-1	hSpCas9	negative selection	1955909
18789246	18789269	19	+	26627737	HCT116	viability after 9 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.5140182071339072	[2169]	[512,320]	-4	hSpCas9	negative selection	1955910
18790016	18790039	19	-	26627737	HCT116	viability after 9 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	-0.2610171957587917	[322]	[138,18]	-2	hSpCas9	negative selection	1955911
18791176	18791199	19	+	26627737	HCT116	viability after 9 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	2.1799110682354907	[148]	[210,155]	9	hSpCas9	negative selection	1955912
18788463	18788486	19	+	26627737	HCT116	viability after 12 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	0.8934779820574362	[93]	[67,116,92]	7	hSpCas9	negative selection	2038222
18788608	18788631	19	-	26627737	HCT116	viability after 12 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.5326567590009474	[81]	[18,57,13]	-5	hSpCas9	negative selection	2038223
18788839	18788862	19	-	26627737	HCT116	viability after 12 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	1.2758205906490263	[124]	[154,177,144]	8	hSpCas9	negative selection	2038224
18789246	18789269	19	+	26627737	HCT116	viability after 12 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.6812619732722038	[1095]	[247,468,372]	-6	hSpCas9	negative selection	2038225
18790016	18790039	19	-	26627737	HCT116	viability after 12 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.236957003407796	[344]	[216,183,238]	2	hSpCas9	negative selection	2038226
18791176	18791199	19	+	26627737	HCT116	viability after 12 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.025482740092709233	[174]	[119,72,84]	0	hSpCas9	negative selection	2038227
18788463	18788486	19	+	26627737	HCT116	viability after 15 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	1.432682663195299	[93]	[265,137,48]	9	hSpCas9	negative selection	2120537
18788608	18788631	19	-	26627737	HCT116	viability after 15 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.5622318417164631	[81]	[65,15,17]	-5	hSpCas9	negative selection	2120538
18788839	18788862	19	-	26627737	HCT116	viability after 15 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.7064891115176414	[124]	[167,103,85]	6	hSpCas9	negative selection	2120539
18789246	18789269	19	+	26627737	HCT116	viability after 15 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.4778219595824946	[1095]	[411,400,536]	-5	hSpCas9	negative selection	2120540
18790016	18790039	19	-	26627737	HCT116	viability after 15 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.360913083683422	[344]	[218,365,174]	3	hSpCas9	negative selection	2120541
18791176	18791199	19	+	26627737	HCT116	viability after 15 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.3488091964064036	[174]	[94,88,54]	-4	hSpCas9	negative selection	2120542
18788463	18788486	19	+	26627737	HCT116	viability after 18 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	1.524092682889537	[93]	[261,51,80]	9	hSpCas9	negative selection	2202852
18788608	18788631	19	-	26627737	HCT116	viability after 18 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.46544652986056234	[81]	[19,41,22]	-4	hSpCas9	negative selection	2202853
18788839	18788862	19	-	26627737	HCT116	viability after 18 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	1.3545471346628932	[124]	[94,166,202]	8	hSpCas9	negative selection	2202854
18789246	18789269	19	+	26627737	HCT116	viability after 18 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.3230538604826534	[1095]	[396,328,556]	-3	hSpCas9	negative selection	2202855
18790016	18790039	19	-	26627737	HCT116	viability after 18 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.4354868072582869	[344]	[328,188,157]	4	hSpCas9	negative selection	2202856
18791176	18791199	19	+	26627737	HCT116	viability after 18 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.35719142040546836	[174]	[62,59,75]	-3	hSpCas9	negative selection	2202857
18787945	18787968	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACTCCAGCCTAG	COMP	ENSG00000105664	-0.533989545843368	[184,280]	[23,46]	-3	dCas9-VP64	positive selection	2477354
18787945	18787968	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACTCCAGCCTAG	COMP	ENSG00000105664	0.47261086320192236	[687,417]	[369,140]	4	dCas9-VP64	positive selection	2572609
18789941	18789964	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACTGCACCGACGTCAACGAGG	COMP	ENSG00000105664	0.9479596485134929	[2,2]	[4,5]	9	hSpCas9	positive selection	2980573
18789244	18789267	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.7528986184982728	[1,1]	[0,0]	-8	hSpCas9	positive selection	2980574
18790885	18790908	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.08012041050924298	[3,3]	[3,2]	1	hSpCas9	positive selection	2980575
18790020	18790043	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGGATGCAGGCCACGCCGGGG	COMP	ENSG00000105664	0.3830268475338125	[2,2]	[3,3]	7	hSpCas9	positive selection	2980576
18789941	18789964	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACTGCACCGACGTCAACGAGG	COMP	ENSG00000105664	-0.06918871451865583	[2,2]	[3,0]	-1	hSpCas9	positive selection	3048431
18789244	18789267	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.03374535618676855	[1,1]	[1,0]	0	hSpCas9	positive selection	3048432
18790885	18790908	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.3461072732496923	[3,3]	[3,3]	6	hSpCas9	positive selection	3048433
18790020	18790043	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGGATGCAGGCCACGCCGGGG	COMP	ENSG00000105664	-0.5438220394627543	[2,2]	[2,0]	-7	hSpCas9	positive selection	3048434
18790871	18790894		+	24336571	A375	resistance to PLX after 7 days	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.03614477631310633	[14,11]	[11,15]	1	hSpCas9	positive selection	3106831
18791240	18791263		+	24336571	A375	resistance to PLX after 7 days	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.3756197627222837	[4,5]	[4,3]	-9	hSpCas9	positive selection	3106832
18791182	18791205		+	24336571	A375	resistance to PLX after 7 days	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	-0.14282729345784329	[6,7]	[6,6]	-4	hSpCas9	positive selection	3106833
18790899	18790922		+	24336571	A375	resistance to PLX after 7 days	TGCAGTTCCCGAAGCATCTGCGG	COMP	ENSG00000105664	0.4552064943807633	[11,9]	[14,15]	9	hSpCas9	positive selection	3106834
18790871	18790894		+	24336571	A375	resistance to PLX after 14 days	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.6059342238137516	[8,8]	[8,2]	5	hSpCas9	positive selection	3164624
18791240	18791263		+	24336571	A375	resistance to PLX after 14 days	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.18534300918585545	[2,4]	[1,2]	2	hSpCas9	positive selection	3164625
18791182	18791205		+	24336571	A375	resistance to PLX after 14 days	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	1.0149129002550212	[9,8]	[7,8]	7	hSpCas9	positive selection	3164626
18790899	18790922		+	24336571	A375	resistance to PLX after 14 days	TGCAGTTCCCGAAGCATCTGCGG	COMP	ENSG00000105664	1.2839062827866192	[11,13]	[18,10]	8	hSpCas9	positive selection	3164627
18790871	18790894		+	24336571	A375	viability after 7 days	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.08578594998437758	[12]	[14,11]	1	hSpCas9	negative selection	3222417
18791240	18791263		+	24336571	A375	viability after 7 days	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.3359365720660832	[4]	[4,5]	5	hSpCas9	negative selection	3222418
18791182	18791205		+	24336571	A375	viability after 7 days	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	-0.009718394317947077	[7]	[6,7]	0	hSpCas9	negative selection	3222419
18790899	18790922		+	24336571	A375	viability after 7 days	TGCAGTTCCCGAAGCATCTGCGG	COMP	ENSG00000105664	-0.023598282239266105	[11]	[11,9]	0	hSpCas9	negative selection	3222420
18790871	18790894		+	24336571	A375	viability after 14 days	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.46800998405890826	[12]	[8,8]	-5	hSpCas9	negative selection	3280210
18791240	18791263		+	24336571	A375	viability after 14 days	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.012261720279199695	[4]	[2,4]	0	hSpCas9	negative selection	3280211
18791182	18791205		+	24336571	A375	viability after 14 days	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.2571933645240623	[7]	[9,8]	3	hSpCas9	negative selection	3280212
18790899	18790922		+	24336571	A375	viability after 14 days	TGCAGTTCCCGAAGCATCTGCGG	COMP	ENSG00000105664	0.2032289704616691	[11]	[11,13]	2	hSpCas9	negative selection	3280213
18791182	18791205	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.5503731863460684	[99,108]	[0,0]	2	hSpCas9	positive selection	3344138
18791206	18791229	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.448708978483577	[126,96]	[0,0]	2	hSpCas9	positive selection	3344139
18790583	18790606	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.6968700989410402	[247,247]	[0,0]	-5	hSpCas9	positive selection	3363365
18791240	18791263	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3363366
18789941	18789964	19	-	26780180	HT29	viability (Avana library 4 designs)	GCACTGCACCGACGTCAACGAGG	COMP	ENSG00000105664	0.955931171212922	[]	[]	3	hSpCas9	negative selection	3417035
18789244	18789267	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.538430418331259	[]	[]	2	hSpCas9	negative selection	3417036
18790885	18790908	19	-	26780180	HT29	viability (Avana library 4 designs)	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	1.34670382999126	[]	[]	5	hSpCas9	negative selection	3417037
18790019	18790042	19	+	26780180	HT29	viability (Avana library 4 designs)	TCTGGATGCAGGCCACGCCGGGG	COMP	ENSG00000105664	2.30328294295253	[]	[]	8	hSpCas9	negative selection	3417038
18790885	18790908	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	1.72157434722688	[]	[]	2	hSpCas9	negative selection	3494851
18790019	18790042	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGATGCAGGCCACGCCGGGG	COMP	ENSG00000105664	2.69586641308668	[]	[]	4	hSpCas9	negative selection	3494852
18789244	18789267	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	1.88807159430614	[]	[]	2	hSpCas9	negative selection	3494853
18789941	18789964	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACTGCACCGACGTCAACGAGG	COMP	ENSG00000105664	2.46773419071227	[]	[]	3	hSpCas9	negative selection	3494854
18789968	18789991	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTTGCCCGTGAAGCCCGCGGGG	COMP	ENSG00000105664	4.27735101593528	[]	[]	7	hSpCas9	negative selection	3494855
18790016	18790039	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	5.35279333967542	[]	[]	8	hSpCas9	negative selection	3494856
18790885	18790908	19	-	26780180	A375	viability (Avana lentiGuide)	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	-0.774381785767655	[]	[]	-1	hSpCas9	negative selection	3603510
18790019	18790042	19	+	26780180	A375	viability (Avana lentiGuide)	TCTGGATGCAGGCCACGCCGGGG	COMP	ENSG00000105664	6.45863149557132	[]	[]	5	hSpCas9	negative selection	3603511
18789244	18789267	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	2.85743051752844	[]	[]	3	hSpCas9	negative selection	3603512
18789941	18789964	19	-	26780180	A375	viability (Avana lentiGuide)	GCACTGCACCGACGTCAACGAGG	COMP	ENSG00000105664	5.82588304984399	[]	[]	5	hSpCas9	negative selection	3603513
18789968	18789991	19	+	26780180	A375	viability (Avana lentiGuide)	CGTTGCCCGTGAAGCCCGCGGGG	COMP	ENSG00000105664	11.8368732053318	[]	[]	7	hSpCas9	negative selection	3603514
18790016	18790039	19	-	26780180	A375	viability (Avana lentiGuide)	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	1.30132296600032	[]	[]	1	hSpCas9	negative selection	3603515
18790885	18790908	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.033343829547595134	[5]	[5,4]	0	hSpCas9	positive selection	3712169
18790019	18790042	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGATGCAGGCCACGCCGGGG	COMP	ENSG00000105664	0.1347683855283289	[4]	[5,4]	3	hSpCas9	positive selection	3712170
18789244	18789267	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.029987947403572357	[3]	[3,2]	0	hSpCas9	positive selection	3712171
18789941	18789964	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACTGCACCGACGTCAACGAGG	COMP	ENSG00000105664	-0.008528400608262238	[4]	[5,3]	0	hSpCas9	positive selection	3712172
18789968	18789991	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTTGCCCGTGAAGCCCGCGGGG	COMP	ENSG00000105664	0.2494442528030905	[3]	[3,4]	7	hSpCas9	positive selection	3712173
18790016	18790039	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.3352480096154528	[4]	[4,5]	8	hSpCas9	positive selection	3712174
18790885	18790908	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	-0.131269488073471	[5]	[3,4]	-2	hSpCas9	positive selection	3820776
18790019	18790042	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGATGCAGGCCACGCCGGGG	COMP	ENSG00000105664	-0.6111040827337012	[5]	[3,0]	-7	hSpCas9	positive selection	3820777
18789244	18789267	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.8156653774535629	[2]	[0,1]	-7	hSpCas9	positive selection	3820778
18789941	18789964	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACTGCACCGACGTCAACGAGG	COMP	ENSG00000105664	-0.09117675314518253	[4]	[4,2]	-1	hSpCas9	positive selection	3820779
18789968	18789991	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTTGCCCGTGAAGCCCGCGGGG	COMP	ENSG00000105664	-0.6134799405523033	[4]	[0,3]	-7	hSpCas9	positive selection	3820780
18790016	18790039	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	-0.007446743182289356	[5]	[4,3]	0	hSpCas9	positive selection	3820781
18790868	18790891	19	-	26780180	A375	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.486694221201416	[]	[]	1	hSpCas9	negative selection	3928791
18790871	18790894	19	+	26780180	A375	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	1.21442441335108	[]	[]	6	hSpCas9	negative selection	3928792
18791240	18791263	19	+	26780180	A375	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	1.28508427468922	[]	[]	7	hSpCas9	negative selection	3928793
18790583	18790606	19	-	26780180	A375	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	1.46460413172196	[]	[]	8	hSpCas9	negative selection	3928794
18791182	18791205	19	+	26780180	A375	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	1.59277577391565	[]	[]	8	hSpCas9	negative selection	3928795
18791206	18791229	19	-	26780180	A375	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	1.39575319204736	[]	[]	7	hSpCas9	negative selection	3928796
18790868	18790891	19	-	26780180	HT29	viability (GeCKOv2 library)	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.681635355854744	[]	[]	2	hSpCas9	negative selection	4036757
18790871	18790894	19	+	26780180	HT29	viability (GeCKOv2 library)	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	1.61519277668228	[]	[]	8	hSpCas9	negative selection	4036758
18791240	18791263	19	+	26780180	HT29	viability (GeCKOv2 library)	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	1.50432449399844	[]	[]	7	hSpCas9	negative selection	4036759
18790583	18790606	19	-	26780180	HT29	viability (GeCKOv2 library)	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	1.5974877575056	[]	[]	8	hSpCas9	negative selection	4036760
18791182	18791205	19	+	26780180	HT29	viability (GeCKOv2 library)	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	2.63981386520795	[]	[]	9	hSpCas9	negative selection	4036761
18791206	18791229	19	-	26780180	HT29	viability (GeCKOv2 library)	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.852578536205544	[]	[]	3	hSpCas9	negative selection	4036762
18790871	18790894	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.0298645415323725	[3]	[1,2]	0	hSpCas9	positive selection	4129041
18791240	18791263	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.1052120041628587	[1]	[0,0]	-2	hSpCas9	positive selection	4129042
18791182	18791205	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.47168368603936794	[2]	[2,3]	8	hSpCas9	positive selection	4129043
18790899	18790922	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCAGTTCCCGAAGCATCTGCGG	COMP	ENSG00000105664	0.013080949291920788	[3]	[1,3]	0	hSpCas9	positive selection	4129044
18790871	18790894	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	1.2441799284530897	[2]	[0,3,2,3]	8	hSpCas9	positive selection	4193063
18791240	18791263	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.11466278872748015	[1]	[0,0,0,0]	-2	hSpCas9	positive selection	4193064
18791182	18791205	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.6310584666222427	[2]	[3,2,1,0]	4	hSpCas9	positive selection	4193065
18790899	18790922	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCAGTTCCCGAAGCATCTGCGG	COMP	ENSG00000105664	0.0768789507918416	[3]	[2,2,0,0]	0	hSpCas9	positive selection	4193066
18791182	18791205	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	-1.007289348420654	[2]	[0,0]	-9	hSpCas9	positive selection	4264379
18791206	18791229	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.1941234099080058	[2]	[2,0]	-4	hSpCas9	positive selection	4264380
18790871	18790894	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.14437758725817523	[4]	[3,2]	-3	hSpCas9	positive selection	4264381
18790868	18790891	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.7839380818656484	[1]	[1,2]	9	hSpCas9	positive selection	4328650
18790583	18790606	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.14256351962672142	[3]	[3,0]	-3	hSpCas9	positive selection	4328651
18791240	18791263	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.5385461892553476	[2]	[2,0]	-8	hSpCas9	positive selection	4328652
18788234	18788256	19	+	27760321	OCIAML3	viability	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.25689308187441773	[1576,1230]	[949,863]	-3	hSpCas9	negative selection	4391041
18788591	18788613	19	-	27760321	OCIAML3	viability	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.15696832434823427	[901,866]	[650,930]	1	hSpCas9	negative selection	4391042
18789934	18789956	19	+	27760321	OCIAML3	viability	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.7016945767249746	[1011,774]	[395,465]	-6	hSpCas9	negative selection	4391043
18787496	18787518	19	-	27760321	OCIAML3	viability	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	0.6100248011741698	[817,628]	[851,863]	7	hSpCas9	negative selection	4391044
18787600	18787622	19	+	27760321	OCIAML3	viability	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.3171306998228165	[1356,1288]	[702,998]	-3	hSpCas9	negative selection	4391045
18788234	18788256	19	+	27760321	OCIAML2	viability	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.1885232197435851	[1576,1230]	[928,1069]	-2	hSpCas9	negative selection	4474504
18788591	18788613	19	-	27760321	OCIAML2	viability	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.3193365203447205	[901,866]	[810,1003]	4	hSpCas9	negative selection	4474505
18789934	18789956	19	+	27760321	OCIAML2	viability	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.3884159670054269	[1011,774]	[484,630]	-4	hSpCas9	negative selection	4474506
18787496	18787518	19	-	27760321	OCIAML2	viability	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	0.11005940666151148	[817,628]	[566,705]	1	hSpCas9	negative selection	4474507
18787600	18787622	19	+	27760321	OCIAML2	viability	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.39471373575336965	[1356,1288]	[767,876]	-5	hSpCas9	negative selection	4474508
18788234	18788256	19	+	27760321	MV411	viability	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.5880792382857238	[1576,1230]	[520,748]	-4	hSpCas9	negative selection	4557967
18788591	18788613	19	-	27760321	MV411	viability	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.738721273947964	[901,866]	[981,965]	5	hSpCas9	negative selection	4557968
18789934	18789956	19	+	27760321	MV411	viability	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	0.13273568173407568	[1011,774]	[796,407]	0	hSpCas9	negative selection	4557969
18787496	18787518	19	-	27760321	MV411	viability	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.24990114852706397	[817,628]	[298,547]	-2	hSpCas9	negative selection	4557970
18787600	18787622	19	+	27760321	MV411	viability	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	0.4956928028996652	[1356,1288]	[1765,430]	3	hSpCas9	negative selection	4557971
18788234	18788256	19	+	27760321	HL60	viability	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.045773176396473714	[1576,1230]	[953,1261]	0	hSpCas9	negative selection	4641430
18788591	18788613	19	-	27760321	HL60	viability	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.43657742929065213	[901,866]	[1094,856]	5	hSpCas9	negative selection	4641431
18789934	18789956	19	+	27760321	HL60	viability	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.015492761241238995	[1011,774]	[785,642]	0	hSpCas9	negative selection	4641432
18787496	18787518	19	-	27760321	HL60	viability	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.12443768688883527	[817,628]	[492,585]	-1	hSpCas9	negative selection	4641433
18787600	18787622	19	+	27760321	HL60	viability	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	0.010945731889271615	[1356,1288]	[1180,993]	0	hSpCas9	negative selection	4641434
18788234	18788256	19	+	27760321	HT1080	viability	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-1.9008620003954688	[1230,960]	[51,187]	-6	hSpCas9	negative selection	4724893
18788591	18788613	19	-	27760321	HT1080	viability	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	-0.05504443096985323	[866,676]	[338,248]	0	hSpCas9	negative selection	4724894
18789934	18789956	19	+	27760321	HT1080	viability	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	0.4499124162631206	[774,604]	[258,502]	2	hSpCas9	negative selection	4724895
18787496	18787518	19	-	27760321	HT1080	viability	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	0.9774078454951132	[628,490]	[317,571]	5	hSpCas9	negative selection	4724896
18787600	18787622	19	+	27760321	HT1080	viability	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.26901381183012885	[1288,1005]	[365,393]	-1	hSpCas9	negative selection	4724897
18788234	18788256	19	+	27760321	HT29	viability after 7 days	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.6557334717969061	[1230,960]	[1120,812,783]	-7	hSpCas9	negative selection	4808356
18788591	18788613	19	-	27760321	HT29	viability after 7 days	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.22827731187769884	[866,676]	[1321,1077,1110]	3	hSpCas9	negative selection	4808357
18789934	18789956	19	+	27760321	HT29	viability after 7 days	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.14849349229943054	[774,604]	[1013,728,690]	-2	hSpCas9	negative selection	4808358
18787496	18787518	19	-	27760321	HT29	viability after 7 days	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.43451597101518624	[628,490]	[320,448,788]	-6	hSpCas9	negative selection	4808359
18787600	18787622	19	+	27760321	HT29	viability after 7 days	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.5580081787512061	[1288,1005]	[1458,988,633]	-7	hSpCas9	negative selection	4808360
18788234	18788256	19	+	27760321	HT29	viability after 25 days	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.5988256924746456	[1230,960]	[745,799,951]	-5	hSpCas9	negative selection	4891819
18788591	18788613	19	-	27760321	HT29	viability after 25 days	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.08811975501367852	[866,676]	[1095,881,810]	0	hSpCas9	negative selection	4891820
18789934	18789956	19	+	27760321	HT29	viability after 25 days	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.2832972179928235	[774,604]	[635,587,727]	-3	hSpCas9	negative selection	4891821
18787496	18787518	19	-	27760321	HT29	viability after 25 days	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.2200531260063075	[628,490]	[458,706,479]	-2	hSpCas9	negative selection	4891822
18787600	18787622	19	+	27760321	HT29	viability after 25 days	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.4026198390280791	[1288,1005]	[1127,949,875]	-4	hSpCas9	negative selection	4891823
18788234	18788256	19	+	27760321	HT29	viability after 22 days	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.37469850346745615	[1230,960]	[1018,780,1131]	-4	hSpCas9	negative selection	4975282
18788591	18788613	19	-	27760321	HT29	viability after 22 days	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.20949369982589539	[866,676]	[1256,885,945]	2	hSpCas9	negative selection	4975283
18789934	18789956	19	+	27760321	HT29	viability after 22 days	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.2003483124860821	[774,604]	[796,689,591]	-2	hSpCas9	negative selection	4975284
18787496	18787518	19	-	27760321	HT29	viability after 22 days	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.45579759818181587	[628,490]	[253,688,478]	-4	hSpCas9	negative selection	4975285
18787600	18787622	19	+	27760321	HT29	viability after 22 days	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.42369333839823486	[1288,1005]	[954,1106,904]	-4	hSpCas9	negative selection	4975286
18788234	18788256	19	+	27760321	HT29	viability after 19 days	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.4745955733823872	[1230,960]	[640,1259,781]	-4	hSpCas9	negative selection	5058745
18788591	18788613	19	-	27760321	HT29	viability after 19 days	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.1204358609962024	[866,676]	[1236,849,825]	1	hSpCas9	negative selection	5058746
18789934	18789956	19	+	27760321	HT29	viability after 19 days	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	0.0413426674790367	[774,604]	[667,601,1137]	0	hSpCas9	negative selection	5058747
18787496	18787518	19	-	27760321	HT29	viability after 19 days	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	0.04497862488516824	[628,490]	[635,676,665]	0	hSpCas9	negative selection	5058748
18787600	18787622	19	+	27760321	HT29	viability after 19 days	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.5989019963100624	[1288,1005]	[1138,663,825]	-5	hSpCas9	negative selection	5058749
18788234	18788256	19	+	27760321	HT29	viability after 16 days	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.7349496779753467	[1230,960]	[551,687,953]	-6	hSpCas9	negative selection	5142208
18788591	18788613	19	-	27760321	HT29	viability after 16 days	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.3068516457826618	[866,676]	[1044,1488,657]	3	hSpCas9	negative selection	5142209
18789934	18789956	19	+	27760321	HT29	viability after 16 days	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.2571858942219978	[774,604]	[823,665,463]	-3	hSpCas9	negative selection	5142210
18787496	18787518	19	-	27760321	HT29	viability after 16 days	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.7419353098207437	[628,490]	[295,389,429]	-6	hSpCas9	negative selection	5142211
18787600	18787622	19	+	27760321	HT29	viability after 16 days	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.5216017164210067	[1288,1005]	[1043,929,721]	-5	hSpCas9	negative selection	5142212
18788234	18788256	19	+	27760321	HT29	viability after 13 days	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.6523940777566393	[1230,960]	[839,868,722]	-6	hSpCas9	negative selection	5225671
18788591	18788613	19	-	27760321	HT29	viability after 13 days	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	-0.24550896862485017	[866,676]	[776,899,598]	-3	hSpCas9	negative selection	5225672
18789934	18789956	19	+	27760321	HT29	viability after 13 days	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.27512511038072207	[774,604]	[730,604,648]	-3	hSpCas9	negative selection	5225673
18787496	18787518	19	-	27760321	HT29	viability after 13 days	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.21698491807480302	[628,490]	[495,674,508]	-3	hSpCas9	negative selection	5225674
18787600	18787622	19	+	27760321	HT29	viability after 13 days	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.6821032992881773	[1288,1005]	[729,960,799]	-6	hSpCas9	negative selection	5225675
18788234	18788256	19	+	27760321	HT29	viability after 10 days	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.8140714703524691	[1230,960]	[943,786,607]	-7	hSpCas9	negative selection	5309134
18788591	18788613	19	-	27760321	HT29	viability after 10 days	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.07248042284235412	[866,676]	[1160,1276,618]	0	hSpCas9	negative selection	5309135
18789934	18789956	19	+	27760321	HT29	viability after 10 days	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.06722276871907584	[774,604]	[701,780,978]	-1	hSpCas9	negative selection	5309136
18787496	18787518	19	-	27760321	HT29	viability after 10 days	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	-0.3936924716912145	[628,490]	[400,699,500]	-5	hSpCas9	negative selection	5309137
18787600	18787622	19	+	27760321	HT29	viability after 10 days	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.5256419055878834	[1288,1005]	[855,1206,929]	-6	hSpCas9	negative selection	5309138
18788234	18788256	19	+	27760321	MOLM13	viability	CCGTCGGCATCCGGATCGCAGG	COMP	ENSG00000105664	-0.3753061698671525	[1576,1230]	[491,703]	-2	hSpCas9	negative selection	5392597
18788591	18788613	19	-	27760321	MOLM13	viability	GATGGCTCGCGGTCGTGCGTGG	COMP	ENSG00000105664	0.387009019207184	[901,866]	[738,580]	2	hSpCas9	negative selection	5392598
18789934	18789956	19	+	27760321	MOLM13	viability	TAGCGCACCTCGTTGACGTCGG	COMP	ENSG00000105664	-0.0823463972884726	[1011,774]	[673,300]	0	hSpCas9	negative selection	5392599
18787496	18787518	19	-	27760321	MOLM13	viability	CGTGCGACGACGACATCGACGG	COMP	ENSG00000105664	0.3827255371529772	[817,628]	[571,490]	2	hSpCas9	negative selection	5392600
18787600	18787622	19	+	27760321	MOLM13	viability	GTCCTCGTCCGTGTTGCGCTGG	COMP	ENSG00000105664	-0.538122724638586	[1356,1288]	[700,355]	-3	hSpCas9	negative selection	5392601
18791234	18791257	19	+	27661255	K562	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.07741290594685497	[809,799]	[709,523]	-3	dCas9-KRAB	negative selection	5472200
18791249	18791272	19	+	27661255	K562	viability	GCAGGCGGTGTCGGGGACCATGG	COMP	ENSG00000105664	-0.11025734842609913	[959,1041]	[777,706]	-4	dCas9-KRAB	negative selection	5472201
18791252	18791275	19	+	27661255	K562	viability	GGCGGTGTCGGGGACCATGGCGG	COMP	ENSG00000105664	-1.3186538802625671	[296,436]	[133,101]	-9	dCas9-KRAB	negative selection	5472202
18791255	18791278	19	+	27661255	K562	viability	GGTGTCGGGGACCATGGCGGTGG	COMP	ENSG00000105664	-1.269065036645178	[1251,1239]	[506,332]	-8	dCas9-KRAB	negative selection	5472203
18790804	18790827	19	-	27661255	K562	viability	GGGAGTGCCAGGGAACGGAAGGG	COMP	ENSG00000105664	0.20298941818627006	[761,832]	[750,715]	7	dCas9-KRAB	negative selection	5472204
18790814	18790837	19	-	27661255	K562	viability	GTGCGGGGCAGGGAGTGCCAGGG	COMP	ENSG00000105664	-0.013295096041605281	[1190,1214]	[1028,885]	0	dCas9-KRAB	negative selection	5472205
18790885	18790908	19	-	27661255	K562	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.19956632182428313	[621,710]	[671,556]	7	dCas9-KRAB	negative selection	5472206
18791182	18791205	19	+	27260156	BXPC3	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.5373415394023409	[312]	[412,488,429,582]	9	hSpCas9	negative selection	5536839
18791206	18791229	19	-	27260156	BXPC3	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.3017830458959544	[324]	[407,456,335,475]	6	hSpCas9	negative selection	5536840
18790871	18790894	19	+	27260156	BXPC3	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.1007651256652069	[1295]	[1174,1380,1592,1723]	2	hSpCas9	negative selection	5536841
18790868	18790891	19	-	27260156	BXPC3	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.529613972454239	[102]	[155,185,105,171]	9	hSpCas9	negative selection	5601110
18790583	18790606	19	-	27260156	BXPC3	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.016706356684927315	[568]	[601,536,577,701]	0	hSpCas9	negative selection	5601111
18791240	18791263	19	+	27260156	BXPC3	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.11118498241089453	[340]	[263,339,356,368]	-3	hSpCas9	negative selection	5601112
18791182	18791205	19	+	27260156	A673	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.2923898667259893	[312]	[673,462,348,374]	7	hSpCas9	negative selection	5658090
18791206	18791229	19	-	27260156	A673	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.16634190457185888	[324]	[455,371,490,434]	4	hSpCas9	negative selection	5658091
18790871	18790894	19	+	27260156	A673	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.09543294950016956	[1295]	[1719,1590,1553,1798]	2	hSpCas9	negative selection	5658092
18790868	18790891	19	-	27260156	A673	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.22588179723071344	[102]	[130,155,91,200]	5	hSpCas9	negative selection	5722361
18790583	18790606	19	-	27260156	A673	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	9.80784284333458e-05	[568]	[689,597,732,714]	0	hSpCas9	negative selection	5722362
18791240	18791263	19	+	27260156	A673	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.09010641592345076	[340]	[402,367,346,424]	-2	hSpCas9	negative selection	5722363
18791182	18791205	19	+	27260156	A375	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.42308823597552814	[312]	[543,478,558,387]	6	hSpCas9	negative selection	5779341
18791206	18791229	19	-	27260156	A375	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.04877038240147019	[324]	[347,499,299,430]	0	hSpCas9	negative selection	5779342
18790871	18790894	19	+	27260156	A375	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.19713562243532423	[1295]	[1233,1624,1414,1073]	-3	hSpCas9	negative selection	5779343
18790868	18790891	19	-	27260156	A375	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.05215737915025276	[102]	[126,229,48,108]	0	hSpCas9	negative selection	5843612
18790583	18790606	19	-	27260156	A375	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.11231433237650396	[568]	[758,641,773,688]	1	hSpCas9	negative selection	5843613
18791240	18791263	19	+	27260156	A375	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.10636101312374652	[340]	[486,373,286,335]	-1	hSpCas9	negative selection	5843614
18791182	18791205	19	+	27260156	COLO741	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.3835002648131119	[312]	[485,678,404]	7	hSpCas9	negative selection	5900592
18791206	18791229	19	-	27260156	COLO741	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.15611542265030753	[324]	[435,349,338]	-3	hSpCas9	negative selection	5900593
18790871	18790894	19	+	27260156	COLO741	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.11740058362970096	[1295]	[1950,1933,1532]	2	hSpCas9	negative selection	5900594
18790868	18790891	19	-	27260156	COLO741	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.7447876450192079	[102]	[333,150,187]	9	hSpCas9	negative selection	5964863
18790583	18790606	19	-	27260156	COLO741	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.2649410829678486	[568]	[864,850,899]	5	hSpCas9	negative selection	5964864
18791240	18791263	19	+	27260156	COLO741	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.4047704291351007	[340]	[304,397,284]	-7	hSpCas9	negative selection	5964865
18791182	18791205	19	+	27260156	CAL120	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.39897730677455356	[312]	[918,363,321]	6	hSpCas9	negative selection	6021843
18791206	18791229	19	-	27260156	CAL120	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.4379498426845566	[324]	[840,271,573]	6	hSpCas9	negative selection	6021844
18790871	18790894	19	+	27260156	CAL120	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.030173282351540598	[1295]	[2094,1421,1302]	0	hSpCas9	negative selection	6021845
18790868	18790891	19	-	27260156	CAL120	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	1.0184938614594583	[102]	[197,335,235]	9	hSpCas9	negative selection	6086114
18790583	18790606	19	-	27260156	CAL120	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.2673630879354134	[568]	[856,1013,688]	4	hSpCas9	negative selection	6086115
18791240	18791263	19	+	27260156	CAL120	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.4741718646843727	[340]	[401,233,294]	-6	hSpCas9	negative selection	6086116
18791182	18791205	19	+	27260156	CADOES1	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.48110177667535636	[312]	[350,425,352,498]	7	hSpCas9	negative selection	6143094
18791206	18791229	19	-	27260156	CADOES1	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.06410664291329199	[324]	[328,340,329,261]	1	hSpCas9	negative selection	6143095
18790871	18790894	19	+	27260156	CADOES1	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.0481152699980365	[1295]	[1284,1187,999,1190]	-1	hSpCas9	negative selection	6143096
18790868	18790891	19	-	27260156	CADOES1	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.17149896834999678	[102]	[103,116,142,65]	3	hSpCas9	negative selection	6207365
18790583	18790606	19	-	27260156	CADOES1	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.14135105976906776	[568]	[753,515,560,499]	2	hSpCas9	negative selection	6207366
18791240	18791263	19	+	27260156	CADOES1	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.16325028107466644	[340]	[307,481,300,328]	3	hSpCas9	negative selection	6207367
18791182	18791205	19	+	27260156	EWS502	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.5864323221563404	[312]	[447,576,446,520]	8	hSpCas9	negative selection	6264345
18791206	18791229	19	-	27260156	EWS502	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.31415394265517366	[324]	[273,686,375,376]	5	hSpCas9	negative selection	6264346
18790871	18790894	19	+	27260156	EWS502	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.06429661075892734	[1295]	[1226,1312,1597,1644]	1	hSpCas9	negative selection	6264347
18790868	18790891	19	-	27260156	EWS502	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.17293205837293923	[102]	[64,88,164,185]	3	hSpCas9	negative selection	6328616
18790583	18790606	19	-	27260156	EWS502	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.12854612015773687	[568]	[769,610,646,587]	2	hSpCas9	negative selection	6328617
18791240	18791263	19	+	27260156	EWS502	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.4087016280133741	[340]	[199,288,321,285]	-6	hSpCas9	negative selection	6328618
18791182	18791205	19	+	27260156	EW8	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.6928477928469712	[312]	[429,362,450,389]	9	hSpCas9	negative selection	6385596
18791206	18791229	19	-	27260156	EW8	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.17868677474905875	[324]	[345,361,186,320]	3	hSpCas9	negative selection	6385597
18790871	18790894	19	+	27260156	EW8	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.08088408259953628	[1295]	[1060,982,1063,856]	-1	hSpCas9	negative selection	6385598
18790868	18790891	19	-	27260156	EW8	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.2846708421170887	[102]	[175,45,115,73]	5	hSpCas9	negative selection	6449867
18790583	18790606	19	-	27260156	EW8	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.34904267965899616	[568]	[594,490,609,647]	6	hSpCas9	negative selection	6449868
18791240	18791263	19	+	27260156	EW8	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.21536650294198728	[340]	[401,245,195,132]	-4	hSpCas9	negative selection	6449869
18791182	18791205	19	+	27260156	CORL105	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.34418202684609034	[312]	[509,470,570,326]	6	hSpCas9	negative selection	6506847
18791206	18791229	19	-	27260156	CORL105	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.348704863635805	[324]	[283,457,474,711]	6	hSpCas9	negative selection	6506848
18790871	18790894	19	+	27260156	CORL105	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.040877798988839587	[1295]	[1219,1371,1758,1584]	0	hSpCas9	negative selection	6506849
18790868	18790891	19	-	27260156	CORL105	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.18999652380933973	[102]	[134,73,130,209]	3	hSpCas9	negative selection	6571118
18790583	18790606	19	-	27260156	CORL105	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.08358993221274677	[568]	[805,533,593,582]	-1	hSpCas9	negative selection	6571119
18791240	18791263	19	+	27260156	CORL105	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.2842816472846544	[340]	[280,451,591,628]	5	hSpCas9	negative selection	6571120
18791182	18791205	19	+	27260156	HS294T	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.46797575334580443	[312]	[153,193,185,128]	6	hSpCas9	negative selection	6628098
18791206	18791229	19	-	27260156	HS294T	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.34475301224674226	[324]	[81,155,68,85]	-5	hSpCas9	negative selection	6628099
18790871	18790894	19	+	27260156	HS294T	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.5722855099766258	[1295]	[528,851,944,653]	7	hSpCas9	negative selection	6628100
18790868	18790891	19	-	27260156	HS294T	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.36497584504099745	[102]	[33,49,39,88]	5	hSpCas9	negative selection	6692369
18790583	18790606	19	-	27260156	HS294T	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.19872096167114633	[568]	[186,161,274,133]	-3	hSpCas9	negative selection	6692370
18791240	18791263	19	+	27260156	HS294T	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.405247148755926	[340]	[115,90,87,101]	-5	hSpCas9	negative selection	6692371
18791182	18791205	19	+	27260156	HCC44	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.6262737462711346	[312]	[619,381,728,512]	8	hSpCas9	negative selection	6749349
18791206	18791229	19	-	27260156	HCC44	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.44335965655312365	[324]	[958,342,427,322]	7	hSpCas9	negative selection	6749350
18790871	18790894	19	+	27260156	HCC44	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.26452746708794805	[1295]	[1789,1510,2468,1429]	4	hSpCas9	negative selection	6749351
18790868	18790891	19	-	27260156	HCC44	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.8009766346669209	[102]	[158,226,165,242]	9	hSpCas9	negative selection	6813620
18790583	18790606	19	-	27260156	HCC44	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.38547785192339257	[568]	[1143,836,775,622]	6	hSpCas9	negative selection	6813621
18791240	18791263	19	+	27260156	HCC44	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.020569487320811652	[340]	[325,281,662,306]	0	hSpCas9	negative selection	6813622
18791182	18791205	19	+	27260156	G402	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.7695850056074857	[312]	[817,302,881,604]	8	hSpCas9	negative selection	6870600
18791206	18791229	19	-	27260156	G402	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.5758623138493629	[324]	[737,312,805,513]	7	hSpCas9	negative selection	6870601
18790871	18790894	19	+	27260156	G402	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.03614530141745931	[1295]	[1556,1973,1556,1122]	0	hSpCas9	negative selection	6870602
18790868	18790891	19	-	27260156	G402	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	-0.46262816787507743	[102]	[77,137,115,35]	-5	hSpCas9	negative selection	6934871
18790583	18790606	19	-	27260156	G402	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.45297105677249905	[568]	[754,1329,1037,681]	5	hSpCas9	negative selection	6934872
18791240	18791263	19	+	27260156	G402	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.25289772761789514	[340]	[242,385,399,352]	-3	hSpCas9	negative selection	6934873
18791182	18791205	19	+	27260156	L33	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.2677170063340995	[312]	[419,153,253,306]	6	hSpCas9	negative selection	6991851
18791206	18791229	19	-	27260156	L33	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.2086783301973809	[324]	[258,114,190,281]	-5	hSpCas9	negative selection	6991852
18790871	18790894	19	+	27260156	L33	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.3832473061775099	[1295]	[1574,691,1132,1697]	7	hSpCas9	negative selection	6991853
18790868	18790891	19	-	27260156	L33	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.3269435793556623	[102]	[127,39,80,161]	7	hSpCas9	negative selection	7056122
18790583	18790606	19	-	27260156	L33	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.18924577433490802	[568]	[579,250,428,720]	4	hSpCas9	negative selection	7056123
18791240	18791263	19	+	27260156	L33	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.33192587801387147	[340]	[331,92,174,244]	-7	hSpCas9	negative selection	7056124
18791182	18791205	19	+	27260156	K562	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.3571516388870446	[312]	[437,600,147,264]	4	hSpCas9	negative selection	7113102
18791206	18791229	19	-	27260156	K562	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.5128874257730106	[324]	[213,462,693,275]	6	hSpCas9	negative selection	7113103
18790871	18790894	19	+	27260156	K562	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.24543613125011965	[1295]	[896,945,1203,837]	-3	hSpCas9	negative selection	7113104
18790868	18790891	19	-	27260156	K562	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.9244879486846858	[102]	[83,34,153,380]	9	hSpCas9	negative selection	7177373
18790583	18790606	19	-	27260156	K562	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.34869309531934106	[568]	[517,336,459,288]	-4	hSpCas9	negative selection	7177374
18791240	18791263	19	+	27260156	K562	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.25054706193732584	[340]	[416,484,180,365]	3	hSpCas9	negative selection	7177375
18791182	18791205	19	+	27260156	HT29	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.4096894283917108	[312]	[510,460,584,462]	7	hSpCas9	negative selection	7234353
18791206	18791229	19	-	27260156	HT29	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.2777051090867568	[324]	[400,488,581,439]	5	hSpCas9	negative selection	7234354
18790871	18790894	19	+	27260156	HT29	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.12162775047375396	[1295]	[1428,1536,1491,1342]	-3	hSpCas9	negative selection	7234355
18790868	18790891	19	-	27260156	HT29	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.5389518776833702	[102]	[125,297,152,157]	9	hSpCas9	negative selection	7298624
18790583	18790606	19	-	27260156	HT29	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.2600543545813214	[568]	[975,925,749,691]	5	hSpCas9	negative selection	7298625
18791240	18791263	19	+	27260156	HT29	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.3322507259845809	[340]	[404,420,277,235]	-6	hSpCas9	negative selection	7298626
18791182	18791205	19	+	27260156	MHHES1	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.4015326110679115	[312]	[568,686,351,313]	7	hSpCas9	negative selection	7355604
18791206	18791229	19	-	27260156	MHHES1	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.334226734958901	[324]	[480,436,455,460]	6	hSpCas9	negative selection	7355605
18790871	18790894	19	+	27260156	MHHES1	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.08984361583925526	[1295]	[1511,1660,1263,1121]	-2	hSpCas9	negative selection	7355606
18790868	18790891	19	-	27260156	MHHES1	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.6764329271349621	[102]	[282,199,147,131]	9	hSpCas9	negative selection	7419875
18790583	18790606	19	-	27260156	MHHES1	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.12975806165519	[568]	[865,699,797,493]	2	hSpCas9	negative selection	7419876
18791240	18791263	19	+	27260156	MHHES1	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.27460577787816015	[340]	[359,485,319,156]	-5	hSpCas9	negative selection	7419877
18791182	18791205	19	+	27260156	MEWO	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.35703977775253803	[312]	[414,338,378]	7	hSpCas9	negative selection	7476855
18791206	18791229	19	-	27260156	MEWO	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.3171507817417163	[324]	[397,394,346]	6	hSpCas9	negative selection	7476856
18790871	18790894	19	+	27260156	MEWO	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.12709469147472374	[1295]	[1585,1299,1136]	3	hSpCas9	negative selection	7476857
18790868	18790891	19	-	27260156	MEWO	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	-0.028224000374991398	[102]	[116,58,111]	0	hSpCas9	negative selection	7541126
18790583	18790606	19	-	27260156	MEWO	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.2189786142648319	[568]	[679,687,501]	5	hSpCas9	negative selection	7541127
18791240	18791263	19	+	27260156	MEWO	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.014721762012824657	[340]	[344,305,301]	0	hSpCas9	negative selection	7541128
18791182	18791205	19	+	27260156	LNCAPCLONEFGC	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.6197304908904185	[312]	[402,402,521,429]	8	hSpCas9	negative selection	7598106
18791206	18791229	19	-	27260156	LNCAPCLONEFGC	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.7010494827255803	[324]	[646,303,529,448]	9	hSpCas9	negative selection	7598107
18790871	18790894	19	+	27260156	LNCAPCLONEFGC	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.0006048062138241939	[1295]	[1103,1115,1535,999]	0	hSpCas9	negative selection	7598108
18790868	18790891	19	-	27260156	LNCAPCLONEFGC	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.30214397297751394	[102]	[131,99,109,117]	5	hSpCas9	negative selection	7662377
18790583	18790606	19	-	27260156	LNCAPCLONEFGC	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.2637636956604469	[568]	[520,593,662,706]	4	hSpCas9	negative selection	7662378
18791240	18791263	19	+	27260156	LNCAPCLONEFGC	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.05891128755203762	[340]	[257,207,494,260]	-1	hSpCas9	negative selection	7662379
18791182	18791205	19	+	27260156	PANC0327	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	1.0211471834398458	[312]	[539,721,669,302]	9	hSpCas9	negative selection	7719357
18791206	18791229	19	-	27260156	PANC0327	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.14167661645741803	[324]	[303,214,339,426]	2	hSpCas9	negative selection	7719358
18790871	18790894	19	+	27260156	PANC0327	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.10118055003457105	[1295]	[1219,1399,1339,956]	1	hSpCas9	negative selection	7719359
18790868	18790891	19	-	27260156	PANC0327	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.1503965926612052	[102]	[122,39,170,81]	2	hSpCas9	negative selection	7783628
18790583	18790606	19	-	27260156	PANC0327	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.008949508039498899	[568]	[747,489,347,469]	0	hSpCas9	negative selection	7783629
18791240	18791263	19	+	27260156	PANC0327	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.1341994550692357	[340]	[411,342,380,198]	2	hSpCas9	negative selection	7783630
18791182	18791205	19	+	27260156	NCIH2009	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.8088431905015507	[312]	[750,653,890]	9	hSpCas9	negative selection	7840608
18791206	18791229	19	-	27260156	NCIH2009	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.19730422012928428	[324]	[276,500,383]	-3	hSpCas9	negative selection	7840609
18790871	18790894	19	+	27260156	NCIH2009	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.2160793414415787	[1295]	[2562,1889,1947]	3	hSpCas9	negative selection	7840610
18790868	18790891	19	-	27260156	NCIH2009	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.5476593772940219	[102]	[178,347,94]	7	hSpCas9	negative selection	7904879
18790583	18790606	19	-	27260156	NCIH2009	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.026101371617069546	[568]	[949,692,813]	0	hSpCas9	negative selection	7904880
18791240	18791263	19	+	27260156	NCIH2009	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.45980110699997906	[340]	[524,760,650]	6	hSpCas9	negative selection	7904881
18791182	18791205	19	+	27260156	NCIH1373	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.5089247579745807	[312]	[344,404,544,182]	5	hSpCas9	negative selection	7961859
18791206	18791229	19	-	27260156	NCIH1373	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.3589749794842053	[324]	[774,220,490,118]	3	hSpCas9	negative selection	7961860
18790871	18790894	19	+	27260156	NCIH1373	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.08821586275567772	[1295]	[2155,903,1198,361]	-1	hSpCas9	negative selection	7961861
18790868	18790891	19	-	27260156	NCIH1373	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	-0.5723895365567686	[102]	[80,7,161,16]	-5	hSpCas9	negative selection	8026130
18790583	18790606	19	-	27260156	NCIH1373	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.06275820367214507	[568]	[702,665,531,142]	0	hSpCas9	negative selection	8026131
18791240	18791263	19	+	27260156	NCIH1373	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.14829351870558838	[340]	[278,521,392,122]	1	hSpCas9	negative selection	8026132
18791182	18791205	19	+	27260156	PATU8902	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	1.054601945437648	[312]	[810,740,653,1551]	9	hSpCas9	negative selection	8083110
18791206	18791229	19	-	27260156	PATU8902	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.07820695407293066	[324]	[406,384,493,636]	0	hSpCas9	negative selection	8083111
18790871	18790894	19	+	27260156	PATU8902	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.7949804679440431	[1295]	[934,788,983,1516]	-6	hSpCas9	negative selection	8083112
18790868	18790891	19	-	27260156	PATU8902	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	-2.17484288552003	[102]	[42,44,13,28]	-9	hSpCas9	negative selection	8147381
18790583	18790606	19	-	27260156	PATU8902	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.32523788319429836	[568]	[909,439,478,744]	-3	hSpCas9	negative selection	8147382
18791240	18791263	19	+	27260156	PATU8902	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.04963487797879895	[340]	[515,384,537,512]	0	hSpCas9	negative selection	8147383
18791182	18791205	19	+	27260156	PANC1	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.38333573769382256	[312]	[377,451,327,271]	6	hSpCas9	negative selection	8204361
18791206	18791229	19	-	27260156	PANC1	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.1479040041542034	[324]	[352,349,294,250]	2	hSpCas9	negative selection	8204362
18790871	18790894	19	+	27260156	PANC1	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.09442629933739854	[1295]	[989,1379,1043,842]	-1	hSpCas9	negative selection	8204363
18790868	18790891	19	-	27260156	PANC1	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.6339614936978337	[102]	[177,127,141,101]	8	hSpCas9	negative selection	8268632
18790583	18790606	19	-	27260156	PANC1	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.1843270601609513	[568]	[580,546,615,478]	3	hSpCas9	negative selection	8268633
18791240	18791263	19	+	27260156	PANC1	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.21059369512938714	[340]	[122,222,207,421]	-3	hSpCas9	negative selection	8268634
18791182	18791205	19	+	27260156	PANC0813	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.3178862326986192	[312]	[449,414,492,472]	5	hSpCas9	negative selection	8325612
18791206	18791229	19	-	27260156	PANC0813	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.01040623749593228	[324]	[435,404,352,349]	0	hSpCas9	negative selection	8325613
18790871	18790894	19	+	27260156	PANC0813	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.3912828236959309	[1295]	[2484,1814,2001,1740]	6	hSpCas9	negative selection	8325614
18790868	18790891	19	-	27260156	PANC0813	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	-0.2221058579603028	[102]	[120,69,79,142]	-4	hSpCas9	negative selection	8389883
18790583	18790606	19	-	27260156	PANC0813	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.0969894488434313	[568]	[717,555,915,671]	1	hSpCas9	negative selection	8389884
18791240	18791263	19	+	27260156	PANC0813	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	0.09415503548367915	[340]	[442,337,495,433]	1	hSpCas9	negative selection	8389885
18791182	18791205	19	+	27260156	RDES	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.775512515764996	[312]	[399,750,596,752]	9	hSpCas9	negative selection	8446863
18791206	18791229	19	-	27260156	RDES	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.5017297796896995	[324]	[392,425,655,696]	7	hSpCas9	negative selection	8446864
18790871	18790894	19	+	27260156	RDES	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.023170438505382362	[1295]	[1237,1322,1702,1891]	0	hSpCas9	negative selection	8446865
18790868	18790891	19	-	27260156	RDES	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.3117845614189654	[102]	[84,104,201,223]	5	hSpCas9	negative selection	8511134
18790583	18790606	19	-	27260156	RDES	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.1995837989068126	[568]	[579,705,713,1072]	3	hSpCas9	negative selection	8511135
18791240	18791263	19	+	27260156	RDES	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.007643600898848968	[340]	[311,365,372,538]	0	hSpCas9	negative selection	8511136
18791182	18791205	19	+	27260156	PC3	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.31793448725596474	[312]	[384,375,473,293]	6	hSpCas9	negative selection	8568114
18791206	18791229	19	-	27260156	PC3	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.35656908068510806	[324]	[232,481,562,479]	7	hSpCas9	negative selection	8568115
18790871	18790894	19	+	27260156	PC3	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.014915616071109916	[1295]	[896,1192,2158,1240]	0	hSpCas9	negative selection	8568116
18790868	18790891	19	-	27260156	PC3	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.590937441071647	[102]	[85,140,337,141]	9	hSpCas9	negative selection	8632385
18790583	18790606	19	-	27260156	PC3	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.047568082761776875	[568]	[386,486,813,628]	-1	hSpCas9	negative selection	8632386
18791240	18791263	19	+	27260156	PC3	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.16572949946686072	[340]	[176,357,506,271]	-4	hSpCas9	negative selection	8632387
18791182	18791205	19	+	27260156	PATU8988T	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.27411673798944214	[312]	[287,368,489,309]	5	hSpCas9	negative selection	8689365
18791206	18791229	19	-	27260156	PATU8988T	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.0109505447060545	[324]	[199,336,396,313]	0	hSpCas9	negative selection	8689366
18790871	18790894	19	+	27260156	PATU8988T	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.0902494501029305	[1295]	[1098,1231,959,1443]	-1	hSpCas9	negative selection	8689367
18790868	18790891	19	-	27260156	PATU8988T	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.591339492303641	[102]	[163,144,144,144]	8	hSpCas9	negative selection	8753636
18790583	18790606	19	-	27260156	PATU8988T	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.18322403304983303	[568]	[349,487,431,683]	-3	hSpCas9	negative selection	8753637
18791240	18791263	19	+	27260156	PATU8988T	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.10220413460844818	[340]	[314,278,401,220]	-2	hSpCas9	negative selection	8753638
18791182	18791205	19	+	27260156	T47D	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.5740926771026036	[312]	[564,526,492,589]	9	hSpCas9	negative selection	8810616
18791206	18791229	19	-	27260156	T47D	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.2710350232838307	[324]	[382,426,519,499]	6	hSpCas9	negative selection	8810617
18790871	18790894	19	+	27260156	T47D	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.04058586823633248	[1295]	[1591,1466,1341,1472]	-1	hSpCas9	negative selection	8810618
18790868	18790891	19	-	27260156	T47D	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.27582276757436075	[102]	[162,150,80,187]	6	hSpCas9	negative selection	8874887
18790583	18790606	19	-	27260156	T47D	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.2715269717244425	[568]	[857,669,630,1063]	6	hSpCas9	negative selection	8874888
18791240	18791263	19	+	27260156	T47D	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.34548551147104073	[340]	[300,326,334,284]	-6	hSpCas9	negative selection	8874889
18791182	18791205	19	+	27260156	SU8686	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.3532310085630175	[312]	[378,420,378,402]	6	hSpCas9	negative selection	8931867
18791206	18791229	19	-	27260156	SU8686	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.07984371249487643	[324]	[286,248,417,269]	-1	hSpCas9	negative selection	8931868
18790871	18790894	19	+	27260156	SU8686	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.17270436201946038	[1295]	[1412,1283,1611,1513]	3	hSpCas9	negative selection	8931869
18790868	18790891	19	-	27260156	SU8686	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.5580389677795488	[102]	[113,141,230,114]	8	hSpCas9	negative selection	8996138
18790583	18790606	19	-	27260156	SU8686	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.18576948522749676	[568]	[498,736,570,778]	3	hSpCas9	negative selection	8996139
18791240	18791263	19	+	27260156	SU8686	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.23457422210284945	[340]	[219,306,300,331]	-4	hSpCas9	negative selection	8996140
18791182	18791205	19	+	27260156	SKES1	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.4224928480245609	[312]	[504,495,442,264]	8	hSpCas9	negative selection	9053118
18791206	18791229	19	-	27260156	SKES1	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	-0.007524396092336794	[324]	[475,367,276,206]	0	hSpCas9	negative selection	9053119
18790871	18790894	19	+	27260156	SKES1	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.07218202962231657	[1295]	[1353,1352,1244,1011]	-1	hSpCas9	negative selection	9053120
18790868	18790891	19	-	27260156	SKES1	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.125714098555036	[102]	[145,137,103,71]	2	hSpCas9	negative selection	9117389
18790583	18790606	19	-	27260156	SKES1	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.11013601033168136	[568]	[453,814,565,611]	2	hSpCas9	negative selection	9117390
18791240	18791263	19	+	27260156	SKES1	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.31891530541566243	[340]	[371,276,239,219]	-6	hSpCas9	negative selection	9117391
18791182	18791205	19	+	27260156	TOV112D	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.5096211699747688	[312]	[511,553,430,322]	8	hSpCas9	negative selection	9174369
18791206	18791229	19	-	27260156	TOV112D	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.3813249511029899	[324]	[321,462,514,396]	7	hSpCas9	negative selection	9174370
18790871	18790894	19	+	27260156	TOV112D	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.05042463741037051	[1295]	[1400,1441,1239,1320]	1	hSpCas9	negative selection	9174371
18790868	18790891	19	-	27260156	TOV112D	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.07872399450970669	[102]	[151,63,60,149]	1	hSpCas9	negative selection	9238640
18790583	18790606	19	-	27260156	TOV112D	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.16326953906648628	[568]	[703,634,601,615]	3	hSpCas9	negative selection	9238641
18791240	18791263	19	+	27260156	TOV112D	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.44717793824429836	[340]	[317,216,320,145]	-7	hSpCas9	negative selection	9238642
18791182	18791205	19	+	27260156	TC71	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.14632498368599628	[312]	[367,460,278,380]	3	hSpCas9	negative selection	9295620
18791206	18791229	19	-	27260156	TC71	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.1532457858868257	[324]	[311,425,405,407]	4	hSpCas9	negative selection	9295621
18790871	18790894	19	+	27260156	TC71	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	-0.002849371904612319	[1295]	[1414,1279,1428,1421]	0	hSpCas9	negative selection	9295622
18790868	18790891	19	-	27260156	TC71	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.43974864183318196	[102]	[214,127,115,138]	8	hSpCas9	negative selection	9359891
18790583	18790606	19	-	27260156	TC71	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	-0.009128286986136158	[568]	[540,593,624,668]	0	hSpCas9	negative selection	9359892
18791240	18791263	19	+	27260156	TC71	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.31387959340141586	[340]	[328,259,346,233]	-7	hSpCas9	negative selection	9359893
18791182	18791205	19	+	27260156	TC32	viability	GCGGCTTACCCAACGGGCTCTGG	COMP	ENSG00000105664	0.6294325435789021	[312]	[452,311,607,503]	9	hSpCas9	negative selection	9416871
18791206	18791229	19	-	27260156	TC32	viability	TGCCCTCGGCGCGTCCGGACAGG	COMP	ENSG00000105664	0.174811229121757	[324]	[457,172,379,407]	3	hSpCas9	negative selection	9416872
18790871	18790894	19	+	27260156	TC32	viability	CACGTCCTGCAGCGCCGCGTTGG	COMP	ENSG00000105664	0.08129772652667899	[1295]	[1251,1034,1699,1257]	1	hSpCas9	negative selection	9416873
18790868	18790891	19	-	27260156	TC32	viability	ACGCGGCGCTGCAGGACGTGCGG	COMP	ENSG00000105664	0.10234738317420788	[102]	[101,32,149,163]	1	hSpCas9	negative selection	9481142
18790583	18790606	19	-	27260156	TC32	viability	GATCACGTTCCTGAAAAACACGG	COMP	ENSG00000105664	0.0326511941686532	[568]	[513,476,691,524]	0	hSpCas9	negative selection	9481143
18791240	18791263	19	+	27260156	TC32	viability	CAGAAGAACGCAGGCGGTGTCGG	COMP	ENSG00000105664	-0.2315505407792559	[340]	[317,129,355,338]	-4	hSpCas9	negative selection	9481144
18788463	18788486	19	+	27869803	HPAFII	viability after 27 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-0.8041804621513491	[217]	[39,86,NaN]	-5	hSpCas9	negative selection	9566533
18788608	18788631	19	-	27869803	HPAFII	viability after 27 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.752878043573812	[87]	[15,36,NaN]	-5	hSpCas9	negative selection	9566534
18788839	18788862	19	-	27869803	HPAFII	viability after 27 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.6748091181036369	[211]	[143,7,NaN]	-5	hSpCas9	negative selection	9566535
18789246	18789269	19	+	27869803	HPAFII	viability after 27 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	0.1718788825587414	[976]	[576,579,NaN]	1	hSpCas9	negative selection	9566536
18790016	18790039	19	-	27869803	HPAFII	viability after 27 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.4257033351793311	[262]	[314,77,NaN]	3	hSpCas9	negative selection	9566537
18791176	18791199	19	+	27869803	HPAFII	viability after 27 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.3487507740715481	[108]	[80,14,NaN]	-3	hSpCas9	negative selection	9566538
18788463	18788486	19	+	27869803	HPAFII	viability after 15 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-0.4740116787023563	[217]	[135,188,NaN]	-5	hSpCas9	negative selection	9648982
18788608	18788631	19	-	27869803	HPAFII	viability after 15 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.09949203163557163	[87]	[51,131,NaN]	1	hSpCas9	negative selection	9648983
18788839	18788862	19	-	27869803	HPAFII	viability after 15 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.6983939497120117	[211]	[243,75,NaN]	-6	hSpCas9	negative selection	9648984
18789246	18789269	19	+	27869803	HPAFII	viability after 15 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.264282581686597	[976]	[1250,639,NaN]	-3	hSpCas9	negative selection	9648985
18790016	18790039	19	-	27869803	HPAFII	viability after 15 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.43756839550751947	[262]	[597,248,NaN]	5	hSpCas9	negative selection	9648986
18791176	18791199	19	+	27869803	HPAFII	viability after 15 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.07590684330327657	[108]	[194,58,NaN]	-1	hSpCas9	negative selection	9648987
18788463	18788486	19	+	27869803	ASPC1	viability after 36 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-1.5996764082423913	[605]	[60,122,32]	-8	hSpCas9	negative selection	9731431
18788608	18788631	19	-	27869803	ASPC1	viability after 36 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.7921466428929191	[135]	[92,91,65]	7	hSpCas9	negative selection	9731432
18788839	18788862	19	-	27869803	ASPC1	viability after 36 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.8301872390251139	[470]	[72,35,149]	-7	hSpCas9	negative selection	9731433
18789246	18789269	19	+	27869803	ASPC1	viability after 36 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	-0.6502756365402471	[2228]	[598,505,409]	-6	hSpCas9	negative selection	9731434
18790016	18790039	19	-	27869803	ASPC1	viability after 36 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.8040379490855539	[691]	[377,514,373]	7	hSpCas9	negative selection	9731435
18791176	18791199	19	+	27869803	ASPC1	viability after 36 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	0.06909490807668606	[329]	[67,132,146]	0	hSpCas9	negative selection	9731436
18788463	18788486	19	+	27869803	PATU8988S	viability after 35 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	0.4822579932231197	[389]	[183,254,NaN]	5	hSpCas9	negative selection	9813880
18788608	18788631	19	-	27869803	PATU8988S	viability after 35 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.3244672595455884	[132]	[99,33,NaN]	3	hSpCas9	negative selection	9813881
18788839	18788862	19	-	27869803	PATU8988S	viability after 35 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.3705624383809858	[386]	[205,196,NaN]	4	hSpCas9	negative selection	9813882
18789246	18789269	19	+	27869803	PATU8988S	viability after 35 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	0.27278638904715824	[1965]	[1005,906,NaN]	3	hSpCas9	negative selection	9813883
18790016	18790039	19	-	27869803	PATU8988S	viability after 35 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.19038108416402066	[568]	[257,264,NaN]	2	hSpCas9	negative selection	9813884
18791176	18791199	19	+	27869803	PATU8988S	viability after 35 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.3057894066743625	[269]	[75,99,NaN]	-3	hSpCas9	negative selection	9813885
18788463	18788486	19	+	27869803	PATU8988S	viability after 31 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	0.08609340917257507	[389]	[128,210,NaN]	1	hSpCas9	negative selection	9896329
18788608	18788631	19	-	27869803	PATU8988S	viability after 31 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	0.49699059875777807	[132]	[91,52,NaN]	6	hSpCas9	negative selection	9896330
18788839	18788862	19	-	27869803	PATU8988S	viability after 31 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	0.08679178818558914	[386]	[173,150,NaN]	1	hSpCas9	negative selection	9896331
18789246	18789269	19	+	27869803	PATU8988S	viability after 31 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	0.027659607668241604	[1965]	[722,895,NaN]	0	hSpCas9	negative selection	9896332
18790016	18790039	19	-	27869803	PATU8988S	viability after 31 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	-0.1819778182612126	[568]	[188,213,NaN]	-2	hSpCas9	negative selection	9896333
18791176	18791199	19	+	27869803	PATU8988S	viability after 31 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.24269757113285761	[269]	[46,146,NaN]	-3	hSpCas9	negative selection	9896334
18788463	18788486	19	+	27869803	HPAFII	viability after 35 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-1.4710267787555449	[217]	[12,69,NaN]	-7	hSpCas9	negative selection	9978778
18788608	18788631	19	-	27869803	HPAFII	viability after 35 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-1.45681872822633	[87]	[3,29,NaN]	-7	hSpCas9	negative selection	9978779
18788839	18788862	19	-	27869803	HPAFII	viability after 35 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.2656843058891283	[211]	[164,3,NaN]	-2	hSpCas9	negative selection	9978780
18789246	18789269	19	+	27869803	HPAFII	viability after 35 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	1.183934799786232	[976]	[785,1503,NaN]	7	hSpCas9	negative selection	9978781
18790016	18790039	19	-	27869803	HPAFII	viability after 35 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.5355675080322921	[262]	[295,76,NaN]	3	hSpCas9	negative selection	9978782
18791176	18791199	19	+	27869803	HPAFII	viability after 35 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.35572586526359173	[108]	[52,31,NaN]	-2	hSpCas9	negative selection	9978783
18788463	18788486	19	+	27869803	HPAFII	viability after 31 days	GGTCAGTGTCGCGACCACAGAGG	COMP	ENSG00000105664	-1.315483965309654	[217]	[7,93,NaN]	-7	hSpCas9	negative selection	10061227
18788608	18788631	19	-	27869803	HPAFII	viability after 31 days	GACTGCGTCCTAGAGCGCGATGG	COMP	ENSG00000105664	-0.7852375452948253	[87]	[20,36,NaN]	-5	hSpCas9	negative selection	10061228
18788839	18788862	19	-	27869803	HPAFII	viability after 31 days	ACTCCGTGTGCATCAACACCCGG	COMP	ENSG00000105664	-0.18010746553375503	[211]	[149,55,NaN]	-1	hSpCas9	negative selection	10061229
18789246	18789269	19	+	27869803	HPAFII	viability after 31 days	CCGGGCTGGTGTTGATACAGCGG	COMP	ENSG00000105664	0.7502822542890526	[976]	[694,1169,NaN]	5	hSpCas9	negative selection	10061230
18790016	18790039	19	-	27869803	HPAFII	viability after 31 days	CGGCGTGGCCTGCATCCAGACGG	COMP	ENSG00000105664	0.05909586907840622	[262]	[237,61,NaN]	0	hSpCas9	negative selection	10061231
18791176	18791199	19	+	27869803	HPAFII	viability after 31 days	GCTAACGCGGCTTACCCAACGGG	COMP	ENSG00000105664	-0.2835563745746741	[108]	[55,43,NaN]	-2	hSpCas9	negative selection	10061232
18791234	18791257	19	+	28162770	P31FUJ	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.05186421024964828	[231]	[262]	0	hSpCas9	negative selection	10136668
18786082	18786105	19	-	28162770	P31FUJ	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.4509823744639123	[170]	[146]	-4	hSpCas9	negative selection	10136669
18790885	18790908	19	-	28162770	P31FUJ	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.207770386971603	[69]	[94]	2	hSpCas9	negative selection	10136670
18790074	18790097	19	-	28162770	P31FUJ	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	-0.3290175196736818	[216]	[202]	-3	hSpCas9	negative selection	10136671
18789244	18789267	19	-	28162770	P31FUJ	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.1663748426754026	[190]	[199]	-2	hSpCas9	negative selection	10136672
18788286	18788309	19	-	28162770	P31FUJ	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.34927778777365615	[166]	[249]	4	hSpCas9	negative selection	10136673
18788267	18788290	19	-	28162770	P31FUJ	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.1925650733056552	[494]	[508]	-2	hSpCas9	negative selection	10136674
18787523	18787546	19	-	28162770	P31FUJ	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.5205578280024961	[244]	[412]	6	hSpCas9	negative selection	10136675
18786581	18786604	19	-	28162770	P31FUJ	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	-0.4186687497257126	[181]	[159]	-4	hSpCas9	negative selection	10136676
18786258	18786281	19	+	28162770	P31FUJ	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-1.0263513269469517	[25]	[14]	-6	hSpCas9	negative selection	10136677
18791234	18791257	19	+	28162770	TF1	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10306034
18786082	18786105	19	-	28162770	TF1	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10306035
18790885	18790908	19	-	28162770	TF1	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10306036
18790074	18790097	19	-	28162770	TF1	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	NaN	[NaN]	[282]	1	hSpCas9	negative selection	10306037
18789244	18789267	19	-	28162770	TF1	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10306038
18788286	18788309	19	-	28162770	TF1	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	NaN	[NaN]	[224]	1	hSpCas9	negative selection	10306039
18788267	18788290	19	-	28162770	TF1	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10306040
18787523	18787546	19	-	28162770	TF1	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10306041
18786581	18786604	19	-	28162770	TF1	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10306042
18786258	18786281	19	+	28162770	TF1	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10306043
18791234	18791257	19	+	28162770	SKM1	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	0.931837714708597	[50]	[171]	8	hSpCas9	negative selection	10475400
18786082	18786105	19	-	28162770	SKM1	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.04049477822805958	[43]	[79]	0	hSpCas9	negative selection	10475401
18790885	18790908	19	-	28162770	SKM1	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.5523938167594924	[26]	[69]	5	hSpCas9	negative selection	10475402
18790074	18790097	19	-	28162770	SKM1	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.4824389701365156	[82]	[204]	5	hSpCas9	negative selection	10475403
18789244	18789267	19	-	28162770	SKM1	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.09553614178602149	[62]	[118]	0	hSpCas9	negative selection	10475404
18788286	18788309	19	-	28162770	SKM1	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	-0.28390580233882357	[72]	[105]	-2	hSpCas9	negative selection	10475405
18788267	18788290	19	-	28162770	SKM1	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.20383830691325389	[82]	[168]	2	hSpCas9	negative selection	10475406
18787523	18787546	19	-	28162770	SKM1	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.4082959213997885	[51]	[121]	4	hSpCas9	negative selection	10475407
18786581	18786604	19	-	28162770	SKM1	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.08242064199576338	[38]	[72]	0	hSpCas9	negative selection	10475408
18786258	18786281	19	+	28162770	SKM1	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-0.1215619798809131	[7]	[12]	-1	hSpCas9	negative selection	10475409
18791234	18791257	19	+	28162770	SKM1	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	0.931837714708597	[50]	[171]	8	hSpCas9	negative selection	10644766
18786082	18786105	19	-	28162770	SKM1	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.04049477822805958	[43]	[79]	0	hSpCas9	negative selection	10644767
18790885	18790908	19	-	28162770	SKM1	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.5523938167594924	[26]	[69]	5	hSpCas9	negative selection	10644768
18790074	18790097	19	-	28162770	SKM1	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.4824389701365156	[82]	[204]	5	hSpCas9	negative selection	10644769
18789244	18789267	19	-	28162770	SKM1	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.09553614178602149	[62]	[118]	0	hSpCas9	negative selection	10644770
18788286	18788309	19	-	28162770	SKM1	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	-0.28390580233882357	[72]	[105]	-2	hSpCas9	negative selection	10644771
18788267	18788290	19	-	28162770	SKM1	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.20383830691325389	[82]	[168]	2	hSpCas9	negative selection	10644772
18787523	18787546	19	-	28162770	SKM1	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.4082959213997885	[51]	[121]	4	hSpCas9	negative selection	10644773
18786581	18786604	19	-	28162770	SKM1	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.08242064199576338	[38]	[72]	0	hSpCas9	negative selection	10644774
18786258	18786281	19	+	28162770	SKM1	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-0.1215619798809131	[7]	[12]	-1	hSpCas9	negative selection	10644775
18791234	18791257	19	+	28162770	PL21	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	0.10788110663733164	[225]	[105]	1	hSpCas9	negative selection	10814132
18786082	18786105	19	-	28162770	PL21	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.18633381496428958	[104]	[51]	1	hSpCas9	negative selection	10814133
18790885	18790908	19	-	28162770	PL21	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	-0.16485720228992817	[84]	[32]	-1	hSpCas9	negative selection	10814134
18790074	18790097	19	-	28162770	PL21	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	-0.1426219838152079	[278]	[109]	-1	hSpCas9	negative selection	10814135
18789244	18789267	19	-	28162770	PL21	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.5492097041327185	[194]	[57]	-4	hSpCas9	negative selection	10814136
18788286	18788309	19	-	28162770	PL21	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.6355257591599665	[175]	[118]	5	hSpCas9	negative selection	10814137
18788267	18788290	19	-	28162770	PL21	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.8151777791159145	[268]	[205]	7	hSpCas9	negative selection	10814138
18787523	18787546	19	-	28162770	PL21	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	1.2842038792777946	[149]	[158]	9	hSpCas9	negative selection	10814139
18786581	18786604	19	-	28162770	PL21	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.18972299854398167	[138]	[68]	1	hSpCas9	negative selection	10814140
18786258	18786281	19	+	28162770	PL21	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-3.323422341567693	[22]	[0]	-9	hSpCas9	negative selection	10814141
18791234	18791257	19	+	28162770	P31FUJ	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.05186421024964828	[231]	[262]	0	hSpCas9	negative selection	10983498
18786082	18786105	19	-	28162770	P31FUJ	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.4509823744639123	[170]	[146]	-4	hSpCas9	negative selection	10983499
18790885	18790908	19	-	28162770	P31FUJ	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.207770386971603	[69]	[94]	2	hSpCas9	negative selection	10983500
18790074	18790097	19	-	28162770	P31FUJ	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	-0.3290175196736818	[216]	[202]	-3	hSpCas9	negative selection	10983501
18789244	18789267	19	-	28162770	P31FUJ	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.1663748426754026	[190]	[199]	-2	hSpCas9	negative selection	10983502
18788286	18788309	19	-	28162770	P31FUJ	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.34927778777365615	[166]	[249]	4	hSpCas9	negative selection	10983503
18788267	18788290	19	-	28162770	P31FUJ	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.1925650733056552	[494]	[508]	-2	hSpCas9	negative selection	10983504
18787523	18787546	19	-	28162770	P31FUJ	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.5205578280024961	[244]	[412]	6	hSpCas9	negative selection	10983505
18786581	18786604	19	-	28162770	P31FUJ	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	-0.4186687497257126	[181]	[159]	-4	hSpCas9	negative selection	10983506
18786258	18786281	19	+	28162770	P31FUJ	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-1.0263513269469517	[25]	[14]	-6	hSpCas9	negative selection	10983507
18791234	18791257	19	+	28162770	OCIAML5	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	0.5981856209989048	[85]	[234]	5	hSpCas9	negative selection	11152864
18786082	18786105	19	-	28162770	OCIAML5	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.026918028174636954	[86]	[159]	0	hSpCas9	negative selection	11152865
18790885	18790908	19	-	28162770	OCIAML5	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.6150594395633004	[16]	[46]	5	hSpCas9	negative selection	11152866
18790074	18790097	19	-	28162770	OCIAML5	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	-0.9813495878089633	[139]	[127]	-6	hSpCas9	negative selection	11152867
18789244	18789267	19	-	28162770	OCIAML5	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.022402547052144048	[107]	[197]	0	hSpCas9	negative selection	11152868
18788286	18788309	19	-	28162770	OCIAML5	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.2707901769215365	[89]	[195]	2	hSpCas9	negative selection	11152869
18788267	18788290	19	-	28162770	OCIAML5	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.5056161568425654	[209]	[266]	-3	hSpCas9	negative selection	11152870
18787523	18787546	19	-	28162770	OCIAML5	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	1.4764043698901375	[87]	[441]	9	hSpCas9	negative selection	11152871
18786581	18786604	19	-	28162770	OCIAML5	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	-0.21663900315985307	[102]	[159]	-1	hSpCas9	negative selection	11152872
18786258	18786281	19	+	28162770	OCIAML5	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	0.23039558932797588	[16]	[35]	2	hSpCas9	negative selection	11152873
18791234	18791257	19	+	28162770	EOL1	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.38665391672376925	[401]	[161]	-3	hSpCas9	negative selection	11322230
18786082	18786105	19	-	28162770	EOL1	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.8465110212640795	[156]	[45]	-5	hSpCas9	negative selection	11322231
18790885	18790908	19	-	28162770	EOL1	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	-0.26639501114086084	[120]	[52]	-2	hSpCas9	negative selection	11322232
18790074	18790097	19	-	28162770	EOL1	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	-0.25119455646709216	[496]	[219]	-2	hSpCas9	negative selection	11322233
18789244	18789267	19	-	28162770	EOL1	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.6345360973250161	[441]	[149]	-4	hSpCas9	negative selection	11322234
18788286	18788309	19	-	28162770	EOL1	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.39253415079833726	[320]	[221]	3	hSpCas9	negative selection	11322235
18788267	18788290	19	-	28162770	EOL1	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.6941890404240302	[453]	[386]	6	hSpCas9	negative selection	11322236
18787523	18787546	19	-	28162770	EOL1	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	-0.4094531556174028	[299]	[118]	-3	hSpCas9	negative selection	11322237
18786581	18786604	19	-	28162770	EOL1	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	-1.3973803233168276	[204]	[40]	-7	hSpCas9	negative selection	11322238
18786258	18786281	19	+	28162770	EOL1	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	0.287117850955243	[27]	[17]	2	hSpCas9	negative selection	11322239
18791234	18791257	19	+	28162770	MOLM13	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.16716416719280022	[336]	[216]	-1	hSpCas9	negative selection	11491596
18786082	18786105	19	-	28162770	MOLM13	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.2408204729986578	[205]	[175]	1	hSpCas9	negative selection	11491597
18790885	18790908	19	-	28162770	MOLM13	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.26735639417187007	[130]	[113]	2	hSpCas9	negative selection	11491598
18790074	18790097	19	-	28162770	MOLM13	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.06156909936684407	[329]	[248]	0	hSpCas9	negative selection	11491599
18789244	18789267	19	-	28162770	MOLM13	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.6312116481626443	[291]	[326]	5	hSpCas9	negative selection	11491600
18788286	18788309	19	-	28162770	MOLM13	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.562526255682654	[235]	[251]	4	hSpCas9	negative selection	11491601
18788267	18788290	19	-	28162770	MOLM13	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.06296571383712679	[470]	[325]	0	hSpCas9	negative selection	11491602
18787523	18787546	19	-	28162770	MOLM13	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.49025719457303335	[255]	[259]	3	hSpCas9	negative selection	11491603
18786581	18786604	19	-	28162770	MOLM13	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.19035540601566991	[239]	[197]	1	hSpCas9	negative selection	11491604
18786258	18786281	19	+	28162770	MOLM13	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	0.40230103991700217	[44]	[42]	3	hSpCas9	negative selection	11491605
18791234	18791257	19	+	28162770	HEL	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.1535144994605948	[355]	[204]	-1	hSpCas9	negative selection	11660962
18786082	18786105	19	-	28162770	HEL	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.7657260133550006	[145]	[54]	-5	hSpCas9	negative selection	11660963
18790885	18790908	19	-	28162770	HEL	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.2478792146591433	[70]	[53]	2	hSpCas9	negative selection	11660964
18790074	18790097	19	-	28162770	HEL	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.794226585185993	[279]	[310]	7	hSpCas9	negative selection	11660965
18789244	18789267	19	-	28162770	HEL	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.8329612476758972	[297]	[339]	7	hSpCas9	negative selection	11660966
18788286	18788309	19	-	28162770	HEL	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.48801623720171483	[235]	[211]	4	hSpCas9	negative selection	11660967
18788267	18788290	19	-	28162770	HEL	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.13900847702411917	[348]	[202]	-1	hSpCas9	negative selection	11660968
18787523	18787546	19	-	28162770	HEL	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.9345049563774668	[231]	[283]	7	hSpCas9	negative selection	11660969
18786581	18786604	19	-	28162770	HEL	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.8303658351761283	[143]	[163]	7	hSpCas9	negative selection	11660970
18786258	18786281	19	+	28162770	HEL	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	1.057776331279201	[26]	[35]	8	hSpCas9	negative selection	11660971
18791234	18791257	19	+	28162770	MV411	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-1.280494004902002	[247]	[85]	-7	hSpCas9	negative selection	11830328
18786082	18786105	19	-	28162770	MV411	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-1.3555588727686425	[160]	[52]	-7	hSpCas9	negative selection	11830329
18790885	18790908	19	-	28162770	MV411	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	1.8393528121456986	[68]	[207]	9	hSpCas9	negative selection	11830330
18790074	18790097	19	-	28162770	MV411	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.6244419180670316	[220]	[286]	5	hSpCas9	negative selection	11830331
18789244	18789267	19	-	28162770	MV411	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	0.13937780492532242	[193]	[179]	1	hSpCas9	negative selection	11830332
18788286	18788309	19	-	28162770	MV411	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	-0.4018753613484385	[148]	[94]	-3	hSpCas9	negative selection	11830333
18788267	18788290	19	-	28162770	MV411	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.4406699257171568	[306]	[350]	4	hSpCas9	negative selection	11830334
18787523	18787546	19	-	28162770	MV411	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.8351454282427488	[174]	[262]	7	hSpCas9	negative selection	11830335
18786581	18786604	19	-	28162770	MV411	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.21294917439748484	[126]	[123]	1	hSpCas9	negative selection	11830336
18786258	18786281	19	+	28162770	MV411	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	0.49536506422636073	[31]	[37]	4	hSpCas9	negative selection	11830337
18791234	18791257	19	+	28162770	MONOMAC1	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.37495463925539646	[180]	[159]	-3	hSpCas9	negative selection	11999694
18786082	18786105	19	-	28162770	MONOMAC1	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.08456211780114109	[73]	[79]	0	hSpCas9	negative selection	11999695
18790885	18790908	19	-	28162770	MONOMAC1	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	-0.4194292683960015	[34]	[29]	-4	hSpCas9	negative selection	11999696
18790074	18790097	19	-	28162770	MONOMAC1	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.7393320467527345	[196]	[376]	7	hSpCas9	negative selection	11999697
18789244	18789267	19	-	28162770	MONOMAC1	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.2872346560311319	[131]	[123]	-3	hSpCas9	negative selection	11999698
18788286	18788309	19	-	28162770	MONOMAC1	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	-0.5291128973229988	[106]	[84]	-4	hSpCas9	negative selection	11999699
18788267	18788290	19	-	28162770	MONOMAC1	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.23592256021655256	[159]	[215]	2	hSpCas9	negative selection	11999700
18787523	18787546	19	-	28162770	MONOMAC1	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.1972420920524927	[104]	[137]	2	hSpCas9	negative selection	11999701
18786581	18786604	19	-	28162770	MONOMAC1	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.10252343479935402	[103]	[127]	1	hSpCas9	negative selection	11999702
18786258	18786281	19	+	28162770	MONOMAC1	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	0.6103180749980504	[23]	[41]	6	hSpCas9	negative selection	11999703
18791234	18791257	19	+	28162770	OCIAML2	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	-0.0625450866050844	[38]	[206]	0	hSpCas9	negative selection	12169060
18786082	18786105	19	-	28162770	OCIAML2	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	0.3481298600876924	[17]	[126]	3	hSpCas9	negative selection	12169061
18790885	18790908	19	-	28162770	OCIAML2	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	1.2094899085193351	[10]	[140]	9	hSpCas9	negative selection	12169062
18790074	18790097	19	-	28162770	OCIAML2	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	1.0472184796204582	[43]	[503]	8	hSpCas9	negative selection	12169063
18789244	18789267	19	-	28162770	OCIAML2	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.09526247139333832	[52]	[274]	-1	hSpCas9	negative selection	12169064
18788286	18788309	19	-	28162770	OCIAML2	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.24453139860569653	[29]	[196]	2	hSpCas9	negative selection	12169065
18788267	18788290	19	-	28162770	OCIAML2	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	-0.1912936070792669	[54]	[266]	-1	hSpCas9	negative selection	12169066
18787523	18787546	19	-	28162770	OCIAML2	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	1.1910254324734795	[28]	[366]	9	hSpCas9	negative selection	12169067
18786581	18786604	19	-	28162770	OCIAML2	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.6404014871465826	[24]	[215]	6	hSpCas9	negative selection	12169068
18786258	18786281	19	+	28162770	OCIAML2	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-0.07831240246340077	[3]	[20]	0	hSpCas9	negative selection	12169069
18791234	18791257	19	+	28162770	OCIAML3	viability	GGTGAGCAGAAGAACGCAGGCGG	COMP	ENSG00000105664	0.3641721839812098	[69]	[271]	3	hSpCas9	negative selection	12338426
18786082	18786105	19	-	28162770	OCIAML3	viability	GGTGCCTAACAGTGCCCAGGAGG	COMP	ENSG00000105664	-0.286579115131916	[39]	[98]	-2	hSpCas9	negative selection	12338427
18790885	18790908	19	-	28162770	OCIAML3	viability	GGAACTGCAGGAAACCAACGCGG	COMP	ENSG00000105664	0.11494357767244645	[25]	[84]	1	hSpCas9	negative selection	12338428
18790074	18790097	19	-	28162770	OCIAML3	viability	GCACCGGCCTACCCAGCGTGCGG	COMP	ENSG00000105664	0.7014482432020082	[54]	[269]	6	hSpCas9	negative selection	12338429
18789244	18789267	19	-	28162770	OCIAML3	viability	GCTGTATCAACACCAGCCCGGGG	COMP	ENSG00000105664	-0.1371499653506923	[50]	[139]	-1	hSpCas9	negative selection	12338430
18788286	18788309	19	-	28162770	OCIAML3	viability	GACTGTGCCCAACTCAGGGCAGG	COMP	ENSG00000105664	0.21723071622066914	[52]	[185]	2	hSpCas9	negative selection	12338431
18788267	18788290	19	-	28162770	OCIAML3	viability	CAGGAGGATGTGGACCGCGATGG	COMP	ENSG00000105664	0.32408116188921954	[76]	[290]	3	hSpCas9	negative selection	12338432
18787523	18787546	19	-	28162770	OCIAML3	viability	GACACAGACCAGGACGGCCGGGG	COMP	ENSG00000105664	0.4245283111132645	[57]	[234]	4	hSpCas9	negative selection	12338433
18786581	18786604	19	-	28162770	OCIAML3	viability	CAGAAGGACAGTGATGGCGATGG	COMP	ENSG00000105664	0.05428079576582228	[51]	[162]	0	hSpCas9	negative selection	12338434
18786258	18786281	19	+	28162770	OCIAML3	viability	AAGCATCTCCCACAAAGTCGTGG	COMP	ENSG00000105664	-0.44200454687911295	[8]	[19]	-3	hSpCas9	negative selection	12338435