Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:9276
• Symbol:COPB2
• Description:COPI coat complex subunit beta 2

DataSource: http://genomecrispr.dkfz.de/#!/results/COPB2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
139373316	139373339	3	-	26472758	Jiyoye	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-2.7303281422440615	[43]	[4]	-9	hSpCas9	negative selection	35585
139373746	139373769	3	-	26472758	Jiyoye	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-6.463189338077531	[116]	[0]	-9	hSpCas9	negative selection	35586
139362406	139362429	3	-	26472758	Jiyoye	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	0.15800362905382498	[144]	[121]	1	hSpCas9	negative selection	35587
139361208	139361231	3	-	26472758	Jiyoye	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.5019502184859534	[322]	[85]	-7	hSpCas9	negative selection	35588
139361123	139361146	3	-	26472758	Jiyoye	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	35589
139379379	139379402	3	-	26472758	Jiyoye	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-2.400179540551731	[6]	[0]	-8	hSpCas9	negative selection	35590
139368179	139368202	3	-	26472758	Jiyoye	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-2.21731548340192	[36]	[5]	-8	hSpCas9	negative selection	35591
139367011	139367034	3	+	26472758	Jiyoye	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-0.47498812820026826	[93]	[50]	-3	hSpCas9	negative selection	35592
139366598	139366621	3	-	26472758	Jiyoye	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-2.0708719152987713	[38]	[6]	-8	hSpCas9	negative selection	35593
139361138	139361161	3	-	26472758	Jiyoye	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-0.8882805020202982	[26]	[10]	-6	hSpCas9	negative selection	35594
139355752	139355775	3	+	26472758	Jiyoye	viability	GCCAAGGATCAGGCTGCTGAGGG	COPB2	ENSG00000184432	-1.8470659058699144	[228]	[47]	-8	hSpCas9	negative selection	102414
139355724	139355747	3	-	26472758	Jiyoye	viability	GAGCCGACTGGCCATCTGGATGG	COPB2	ENSG00000184432	-0.16314034325088145	[195]	[131]	-1	hSpCas9	negative selection	102418
139373316	139373339	3	-	26472758	KBM7	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.8982054471986742	[393,395]	[57,42]	-8	hSpCas9	negative selection	226703
139373746	139373769	3	-	26472758	KBM7	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-2.6593032149128115	[242,264]	[26,11]	-9	hSpCas9	negative selection	226704
139362406	139362429	3	-	26472758	KBM7	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-0.21046200344834642	[725,562]	[310,213]	-2	hSpCas9	negative selection	226705
139361208	139361231	3	-	26472758	KBM7	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-0.8463399667488795	[853,983]	[351,145]	-6	hSpCas9	negative selection	226706
139361123	139361146	3	-	26472758	KBM7	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-5.689733599113335	[111,106]	[0,0]	-9	hSpCas9	negative selection	226707
139379379	139379402	3	-	26472758	KBM7	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-4.1872702924757865	[187,147]	[7,0]	-9	hSpCas9	negative selection	226708
139368179	139368202	3	-	26472758	KBM7	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-4.4561318573125375	[156,124]	[2,2]	-9	hSpCas9	negative selection	226709
139367011	139367034	3	+	26472758	KBM7	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-2.294400831469125	[426,488]	[45,42]	-8	hSpCas9	negative selection	226710
139366598	139366621	3	-	26472758	KBM7	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-3.831838455927558	[308,408]	[19,4]	-9	hSpCas9	negative selection	226711
139361138	139361161	3	-	26472758	KBM7	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	0.16737233127309725	[88,75]	[25,58]	1	hSpCas9	negative selection	226712
139355752	139355775	3	+	26472758	KBM7	viability	GCCAAGGATCAGGCTGCTGAGGG	COPB2	ENSG00000184432	-0.051979166907641254	[576,417]	[240,206]	0	hSpCas9	negative selection	293532
139355724	139355747	3	-	26472758	KBM7	viability	GAGCCGACTGGCCATCTGGATGG	COPB2	ENSG00000184432	-0.5837967580058995	[971,527]	[232,225]	-5	hSpCas9	negative selection	293536
139373316	139373339	3	-	26472758	Raji	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.6523533664512646	[148]	[10]	-8	hSpCas9	negative selection	417821
139373746	139373769	3	-	26472758	Raji	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-3.846812775013276	[123]	[1]	-9	hSpCas9	negative selection	417822
139362406	139362429	3	-	26472758	Raji	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	0.08535722904360071	[263]	[64]	0	hSpCas9	negative selection	417823
139361208	139361231	3	-	26472758	Raji	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.218546490071259	[360]	[35]	-7	hSpCas9	negative selection	417824
139361123	139361146	3	-	26472758	Raji	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-4.352048083263698	[87]	[0]	-9	hSpCas9	negative selection	417825
139379379	139379402	3	-	26472758	Raji	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-2.750597459753973	[28]	[0]	-9	hSpCas9	negative selection	417826
139368179	139368202	3	-	26472758	Raji	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-0.28493388740516057	[41]	[7]	-2	hSpCas9	negative selection	417827
139367011	139367034	3	+	26472758	Raji	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-3.725506478791142	[284]	[4]	-9	hSpCas9	negative selection	417828
139366598	139366621	3	-	26472758	Raji	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-3.529241085170049	[198]	[3]	-9	hSpCas9	negative selection	417829
139361138	139361161	3	-	26472758	Raji	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-3.5364726544011256	[49]	[0]	-9	hSpCas9	negative selection	417830
139355752	139355775	3	+	26472758	Raji	viability	GCCAAGGATCAGGCTGCTGAGGG	COPB2	ENSG00000184432	-1.4458701056202188	[269]	[22]	-7	hSpCas9	negative selection	484650
139355724	139355747	3	-	26472758	Raji	viability	GAGCCGACTGGCCATCTGGATGG	COPB2	ENSG00000184432	-0.21866066798599465	[350]	[69]	-2	hSpCas9	negative selection	484654
139373316	139373339	3	-	26472758	K562	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-0.5178302306205271	[306]	[180]	-3	hSpCas9	negative selection	608939
139373746	139373769	3	-	26472758	K562	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-7.9305069548342315	[288]	[0]	-9	hSpCas9	negative selection	608940
139362406	139362429	3	-	26472758	K562	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	0.5368926800632942	[573]	[702]	4	hSpCas9	negative selection	608941
139361208	139361231	3	-	26472758	K562	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-0.15868856152941513	[561]	[424]	-1	hSpCas9	negative selection	608942
139361123	139361146	3	-	26472758	K562	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-5.198524768182281	[86]	[1]	-9	hSpCas9	negative selection	608943
139379379	139379402	3	-	26472758	K562	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-5.0954312752181785	[80]	[1]	-9	hSpCas9	negative selection	608944
139368179	139368202	3	-	26472758	K562	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-3.782381331677268	[162]	[9]	-9	hSpCas9	negative selection	608945
139367011	139367034	3	+	26472758	K562	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-1.7396748814241922	[450]	[113]	-7	hSpCas9	negative selection	608946
139366598	139366621	3	-	26472758	K562	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-0.31239273274056023	[202]	[137]	-2	hSpCas9	negative selection	608947
139361138	139361161	3	-	26472758	K562	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-0.5905220260630566	[65]	[36]	-4	hSpCas9	negative selection	608948
139355752	139355775	3	+	26472758	K562	viability	GCCAAGGATCAGGCTGCTGAGGG	COPB2	ENSG00000184432	0.06571284068192462	[308]	[272]	0	hSpCas9	negative selection	675768
139355724	139355747	3	-	26472758	K562	viability	GAGCCGACTGGCCATCTGGATGG	COPB2	ENSG00000184432	-0.3701385552430053	[590]	[385]	-2	hSpCas9	negative selection	675772
139366648	139366671	3	-	26627737	DLD1	viability	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-2.3637462531920965	[524]	[1,27,60]	-9	hSpCas9	negative selection	819764
139369355	139369378	3	-	26627737	DLD1	viability	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-2.4588654294334393	[320]	[20,34,1]	-9	hSpCas9	negative selection	819765
139373261	139373284	3	+	26627737	DLD1	viability	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-2.8987924790502286	[586]	[40,12,19]	-9	hSpCas9	negative selection	819766
139373714	139373737	3	-	26627737	DLD1	viability	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.6440356541031496	[275]	[37,8,33]	-8	hSpCas9	negative selection	819767
139378041	139378064	3	+	26627737	DLD1	viability	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.2163870022364307	[747]	[113,41,1]	-9	hSpCas9	negative selection	819768
139379411	139379434	3	+	26627737	DLD1	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.6440341493946102	[794]	[417,527,246]	6	hSpCas9	negative selection	819769
139366648	139366671	3	-	26627737	GBM cells	viability after 5 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.6288237571425208	[172]	[7,51]	-9	hSpCas9	negative selection	902079
139369355	139369378	3	-	26627737	GBM cells	viability after 5 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-2.1362143485179166	[290]	[20,49]	-9	hSpCas9	negative selection	902080
139373261	139373284	3	+	26627737	GBM cells	viability after 5 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-1.2626476536220002	[386]	[75,96]	-9	hSpCas9	negative selection	902081
139373714	139373737	3	-	26627737	GBM cells	viability after 5 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.1010861251143147	[175]	[27,59]	-9	hSpCas9	negative selection	902082
139378041	139378064	3	+	26627737	GBM cells	viability after 5 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.4391539226569297	[808]	[36,42]	-9	hSpCas9	negative selection	902083
139379411	139379434	3	+	26627737	GBM cells	viability after 5 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.4620672281605054	[510]	[381,372]	7	hSpCas9	negative selection	902084
139366648	139366671	3	-	26627737	GBM cells	viability after 13 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.5113491324560195	[172]	[22,40]	-9	hSpCas9	negative selection	984394
139369355	139369378	3	-	26627737	GBM cells	viability after 13 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-1.7072404768984928	[290]	[65,33]	-9	hSpCas9	negative selection	984395
139373261	139373284	3	+	26627737	GBM cells	viability after 13 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-1.5615035278971674	[386]	[74,67]	-9	hSpCas9	negative selection	984396
139373714	139373737	3	-	26627737	GBM cells	viability after 13 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-2.093038692805644	[175]	[28,16]	-9	hSpCas9	negative selection	984397
139378041	139378064	3	+	26627737	GBM cells	viability after 13 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-5.256176871959891	[808]	[16,6]	-9	hSpCas9	negative selection	984398
139379411	139379434	3	+	26627737	GBM cells	viability after 13 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.7169526588927932	[510]	[538,387]	8	hSpCas9	negative selection	984399
139366648	139366671	3	-	26627737	GBM cells	viability after 21 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.001512398293832	[172]	[59,34]	-7	hSpCas9	negative selection	1066709
139369355	139369378	3	-	26627737	GBM cells	viability after 21 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-1.6017382852000521	[290]	[49,53]	-8	hSpCas9	negative selection	1066710
139373261	139373284	3	+	26627737	GBM cells	viability after 21 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-2.1965822974351727	[386]	[48,42]	-9	hSpCas9	negative selection	1066711
139373714	139373737	3	-	26627737	GBM cells	viability after 21 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-3.587235638087057	[175]	[8,6]	-9	hSpCas9	negative selection	1066712
139378041	139378064	3	+	26627737	GBM cells	viability after 21 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.609837591372007	[808]	[35,35]	-9	hSpCas9	negative selection	1066713
139379411	139379434	3	+	26627737	GBM cells	viability after 21 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.9992244728048532	[510]	[626,488]	8	hSpCas9	negative selection	1066714
139366648	139366671	3	-	26627737	RPE1	viability after 9 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	1.3788671710354692	[87]	[82,56]	7	hSpCas9	negative selection	1149024
139369355	139369378	3	-	26627737	RPE1	viability after 9 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-6.708257762159233	[333]	[0,0]	-9	hSpCas9	negative selection	1149025
139373261	139373284	3	+	26627737	RPE1	viability after 9 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-4.901542228055833	[553]	[0,11]	-9	hSpCas9	negative selection	1149026
139373714	139373737	3	-	26627737	RPE1	viability after 9 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-3.115642477762333	[635]	[39,0]	-9	hSpCas9	negative selection	1149027
139378041	139378064	3	+	26627737	RPE1	viability after 9 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-8.179421852945417	[925]	[0,0]	-9	hSpCas9	negative selection	1149028
139379411	139379434	3	+	26627737	RPE1	viability after 9 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.2035887771687026	[1234]	[569,1303]	7	hSpCas9	negative selection	1149029
139366648	139366671	3	-	26627737	RPE1	viability after 12 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	1.5392179547482785	[87]	[109,24]	8	hSpCas9	negative selection	1231339
139369355	139369378	3	-	26627737	RPE1	viability after 12 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-5.141142466779483	[333]	[3,0]	-9	hSpCas9	negative selection	1231340
139373261	139373284	3	+	26627737	RPE1	viability after 12 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-7.217630754376051	[553]	[0,0]	-9	hSpCas9	negative selection	1231341
139373714	139373737	3	-	26627737	RPE1	viability after 12 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-3.353761746085417	[635]	[6,26]	-9	hSpCas9	negative selection	1231342
139378041	139378064	3	+	26627737	RPE1	viability after 12 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-5.928168651753675	[925]	[6,0]	-9	hSpCas9	negative selection	1231343
139379411	139379434	3	+	26627737	RPE1	viability after 12 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.1756832455035804	[1234]	[750,747]	7	hSpCas9	negative selection	1231344
139366648	139366671	3	-	26627737	RPE1	viability after 15 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	1.1336722738783016	[87]	[75,33]	6	hSpCas9	negative selection	1313654
139369355	139369378	3	-	26627737	RPE1	viability after 15 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-6.5619554186021585	[333]	[0,0]	-9	hSpCas9	negative selection	1313655
139373261	139373284	3	+	26627737	RPE1	viability after 15 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-4.269324216827578	[553]	[0,14]	-9	hSpCas9	negative selection	1313656
139373714	139373737	3	-	26627737	RPE1	viability after 15 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-2.8019108302207707	[635]	[8,41]	-9	hSpCas9	negative selection	1313657
139378041	139378064	3	+	26627737	RPE1	viability after 15 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-5.149038796687909	[925]	[13,0]	-9	hSpCas9	negative selection	1313658
139379411	139379434	3	+	26627737	RPE1	viability after 15 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.236138710466156	[1234]	[599,1037]	7	hSpCas9	negative selection	1313659
139366648	139366671	3	-	26627737	RPE1	viability after 18 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	1.0978274800305305	[87]	[74,24]	6	hSpCas9	negative selection	1395969
139369355	139369378	3	-	26627737	RPE1	viability after 18 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-5.893207126193133	[333]	[1,0]	-9	hSpCas9	negative selection	1395970
139373261	139373284	3	+	26627737	RPE1	viability after 18 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-4.80434332388263	[553]	[0,9]	-9	hSpCas9	negative selection	1395971
139373714	139373737	3	-	26627737	RPE1	viability after 18 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-3.9421900600603372	[635]	[15,5]	-9	hSpCas9	negative selection	1395972
139378041	139378064	3	+	26627737	RPE1	viability after 18 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-7.9652001231594936	[925]	[0,0]	-9	hSpCas9	negative selection	1395973
139379411	139379434	3	+	26627737	RPE1	viability after 18 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.1661942642056538	[1234]	[469,1044]	6	hSpCas9	negative selection	1395974
139366648	139366671	3	-	26627737	HeLa	viability after 8 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-2.5179044624778997	[363]	[38,11,33]	-9	hSpCas9	negative selection	1478284
139369355	139369378	3	-	26627737	HeLa	viability after 8 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-4.416120527204527	[425]	[5,3,14]	-9	hSpCas9	negative selection	1478285
139373261	139373284	3	+	26627737	HeLa	viability after 8 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-1.0292804784862102	[278]	[74,4,98]	-8	hSpCas9	negative selection	1478286
139373714	139373737	3	-	26627737	HeLa	viability after 8 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-0.6384235239868834	[419]	[73,259,15]	-6	hSpCas9	negative selection	1478287
139378041	139378064	3	+	26627737	HeLa	viability after 8 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.0512913707836247	[914]	[91,31,30]	-9	hSpCas9	negative selection	1478288
139379411	139379434	3	+	26627737	HeLa	viability after 8 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.4469517740338653	[655]	[416,478,284]	4	hSpCas9	negative selection	1478289
139366648	139366671	3	-	26627737	HeLa	viability after 12 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-3.4862679167209354	[363]	[0,21,15]	-9	hSpCas9	negative selection	1560599
139369355	139369378	3	-	26627737	HeLa	viability after 12 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-2.1162448311010666	[425]	[74,19,29]	-9	hSpCas9	negative selection	1560600
139373261	139373284	3	+	26627737	HeLa	viability after 12 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-0.356827284355619	[278]	[79,59,132]	-3	hSpCas9	negative selection	1560601
139373714	139373737	3	-	26627737	HeLa	viability after 12 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.0858900860279046	[419]	[50,113,75]	-7	hSpCas9	negative selection	1560602
139378041	139378064	3	+	26627737	HeLa	viability after 12 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.887140904069633	[914]	[38,50,62]	-9	hSpCas9	negative selection	1560603
139379411	139379434	3	+	26627737	HeLa	viability after 12 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.581739002222138	[655]	[287,554,354]	5	hSpCas9	negative selection	1560604
139366648	139366671	3	-	26627737	HeLa	viability after 15 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.9918996828848683	[363]	[22,38,50]	-9	hSpCas9	negative selection	1642914
139369355	139369378	3	-	26627737	HeLa	viability after 15 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-2.656703230858544	[425]	[14,11,57]	-9	hSpCas9	negative selection	1642915
139373261	139373284	3	+	26627737	HeLa	viability after 15 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-1.3751613811597068	[278]	[41,13,77]	-8	hSpCas9	negative selection	1642916
139373714	139373737	3	-	26627737	HeLa	viability after 15 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-0.7556753656414543	[419]	[120,99,80]	-6	hSpCas9	negative selection	1642917
139378041	139378064	3	+	26627737	HeLa	viability after 15 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.3931503494009316	[914]	[141,44,20]	-9	hSpCas9	negative selection	1642918
139379411	139379434	3	+	26627737	HeLa	viability after 15 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.858007676403314	[655]	[459,489,503]	6	hSpCas9	negative selection	1642919
139366648	139366671	3	-	26627737	HeLa	viability after 18 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.9616916739756185	[363]	[17,30,50]	-9	hSpCas9	negative selection	1725229
139369355	139369378	3	-	26627737	HeLa	viability after 18 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-2.6356486670864294	[425]	[9,10,57]	-9	hSpCas9	negative selection	1725230
139373261	139373284	3	+	26627737	HeLa	viability after 18 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-1.389709008195273	[278]	[26,11,77]	-8	hSpCas9	negative selection	1725231
139373714	139373737	3	-	26627737	HeLa	viability after 18 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-0.6595566988998716	[419]	[88,89,80]	-5	hSpCas9	negative selection	1725232
139378041	139378064	3	+	26627737	HeLa	viability after 18 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.3753369541857094	[914]	[93,40,20]	-9	hSpCas9	negative selection	1725233
139379411	139379434	3	+	26627737	HeLa	viability after 18 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.8496617694116215	[655]	[318,385,503]	6	hSpCas9	negative selection	1725234
139366648	139366671	3	-	26627737	HCT116	viability after 6 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-2.1914801470645044	[438]	[27,7]	-8	hSpCas9	negative selection	1807544
139369355	139369378	3	-	26627737	HCT116	viability after 6 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-4.1141049201454605	[579]	[12,0]	-9	hSpCas9	negative selection	1807545
139373261	139373284	3	+	26627737	HCT116	viability after 6 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	0.3725570886966708	[1041]	[155,242]	2	hSpCas9	negative selection	1807546
139373714	139373737	3	-	26627737	HCT116	viability after 6 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	0.16552961442466313	[618]	[54,138]	0	hSpCas9	negative selection	1807547
139378041	139378064	3	+	26627737	HCT116	viability after 6 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.7198804714949913	[1547]	[2,26]	-9	hSpCas9	negative selection	1807548
139379411	139379434	3	+	26627737	HCT116	viability after 6 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.5938127719167208	[802]	[127,224]	3	hSpCas9	negative selection	1807549
139366648	139366671	3	-	26627737	HCT116	viability after 8 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.5654520915869126	[301]	[99,57,11]	-9	hSpCas9	negative selection	1889859
139369355	139369378	3	-	26627737	HCT116	viability after 8 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-4.847424563164915	[403]	[2,2,16]	-9	hSpCas9	negative selection	1889860
139373261	139373284	3	+	26627737	HCT116	viability after 8 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-0.8651351076134732	[427]	[135,160,91]	-8	hSpCas9	negative selection	1889861
139373714	139373737	3	-	26627737	HCT116	viability after 8 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-2.093763363209739	[354]	[70,26,39]	-9	hSpCas9	negative selection	1889862
139378041	139378064	3	+	26627737	HCT116	viability after 8 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.4701115358487566	[762]	[72,112,41]	-9	hSpCas9	negative selection	1889863
139379411	139379434	3	+	26627737	HCT116	viability after 8 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.49397229839911805	[544]	[469,406,392]	5	hSpCas9	negative selection	1889864
139366648	139366671	3	-	26627737	HCT116	viability after 9 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-0.4550067993380474	[438]	[175,13]	-3	hSpCas9	negative selection	1972174
139369355	139369378	3	-	26627737	HCT116	viability after 9 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-5.855016024210806	[579]	[0,3]	-9	hSpCas9	negative selection	1972175
139373261	139373284	3	+	26627737	HCT116	viability after 9 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-0.6906393367192877	[1041]	[368,16]	-5	hSpCas9	negative selection	1972176
139373714	139373737	3	-	26627737	HCT116	viability after 9 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.2729573771897926	[618]	[35,93]	-7	hSpCas9	negative selection	1972177
139378041	139378064	3	+	26627737	HCT116	viability after 9 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.1264153260074155	[1547]	[5,79]	-9	hSpCas9	negative selection	1972178
139379411	139379434	3	+	26627737	HCT116	viability after 9 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.3142373526100435	[802]	[869,266]	8	hSpCas9	negative selection	1972179
139366648	139366671	3	-	26627737	HCT116	viability after 12 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.5420554960349053	[301]	[91,45,21]	-9	hSpCas9	negative selection	2054489
139369355	139369378	3	-	26627737	HCT116	viability after 12 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-4.6965372727124715	[403]	[3,10,9]	-9	hSpCas9	negative selection	2054490
139373261	139373284	3	+	26627737	HCT116	viability after 12 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-1.977711936114389	[427]	[60,57,51]	-9	hSpCas9	negative selection	2054491
139373714	139373737	3	-	26627737	HCT116	viability after 12 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.6818223818234657	[354]	[68,78,25]	-9	hSpCas9	negative selection	2054492
139378041	139378064	3	+	26627737	HCT116	viability after 12 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.4676615057327864	[762]	[53,28,23]	-9	hSpCas9	negative selection	2054493
139379411	139379434	3	+	26627737	HCT116	viability after 12 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.22018845246665653	[544]	[253,419,335]	2	hSpCas9	negative selection	2054494
139366648	139366671	3	-	26627737	HCT116	viability after 15 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.8621479475295533	[301]	[117,12,20]	-9	hSpCas9	negative selection	2136804
139369355	139369378	3	-	26627737	HCT116	viability after 15 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-6.233177364472014	[403]	[0,4,2]	-9	hSpCas9	negative selection	2136805
139373261	139373284	3	+	26627737	HCT116	viability after 15 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-1.5936556746158859	[427]	[52,117,69]	-8	hSpCas9	negative selection	2136806
139373714	139373737	3	-	26627737	HCT116	viability after 15 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-2.590947798535148	[354]	[19,59,19]	-9	hSpCas9	negative selection	2136807
139378041	139378064	3	+	26627737	HCT116	viability after 15 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.4452420593296513	[762]	[51,19,49]	-9	hSpCas9	negative selection	2136808
139379411	139379434	3	+	26627737	HCT116	viability after 15 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.673441282981656	[544]	[437,378,670]	6	hSpCas9	negative selection	2136809
139366648	139366671	3	-	26627737	HCT116	viability after 18 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-2.0581392659199027	[301]	[79,0,25]	-9	hSpCas9	negative selection	2219119
139369355	139369378	3	-	26627737	HCT116	viability after 18 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-4.758507195851172	[403]	[14,0,5]	-9	hSpCas9	negative selection	2219120
139373261	139373284	3	+	26627737	HCT116	viability after 18 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-2.258234873664132	[427]	[21,66,38]	-9	hSpCas9	negative selection	2219121
139373714	139373737	3	-	26627737	HCT116	viability after 18 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.9839426713758028	[354]	[15,55,57]	-9	hSpCas9	negative selection	2219122
139378041	139378064	3	+	26627737	HCT116	viability after 18 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.234603554880323	[762]	[31,46,37]	-9	hSpCas9	negative selection	2219123
139379411	139379434	3	+	26627737	HCT116	viability after 18 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.8818214488050692	[544]	[647,277,546]	7	hSpCas9	negative selection	2219124
139375494	139375517	3	+	27260157	DLD1	viability	GGTCATCTGCACCTGAAATGAGG	COPB2	ENSG00000184432	-2.54308153404497	[]	[]	-9	hSpCas9	negative selection	2575047
139373755	139373778	3	+	27260157	DLD1	viability	AATTCAGTGTGCTCTCAAGCCGG	COPB2	ENSG00000184432	-1.85005669941217	[]	[]	-8	hSpCas9	negative selection	2576244
139389638	139389661	3	+	27260157	DLD1	viability	CTGACTGACGTGGAACTTCCGGG	COPB2	ENSG00000184432	0.361466588727344	[]	[]	4	hSpCas9	negative selection	2577018
139389656	139389679	3	-	27260157	DLD1	viability	CTATCGCGAGAATCGGCTCCCGG	COPB2	ENSG00000184432	-0.894766662863576	[]	[]	-6	hSpCas9	negative selection	2577662
139389614	139389637	3	-	27260157	DLD1	viability	CTGACGGTCAGTGGATCGGTGGG	COPB2	ENSG00000184432	-0.928077189596363	[]	[]	-6	hSpCas9	negative selection	2581528
139389570	139389593	3	+	27260157	DLD1	viability	CGGGAACCCTCGTTTGTTACCGG	COPB2	ENSG00000184432	-0.0476364637402632	[]	[]	0	hSpCas9	negative selection	2581742
139375505	139375528	3	-	27260157	DLD1	viability	GACAAGCCATACCTCATTTCAGG	COPB2	ENSG00000184432	-3.87670338788289	[]	[]	-9	hSpCas9	negative selection	2582201
139389563	139389586	3	-	27260157	DLD1	viability	CAAACGAGGGTTCCCGGGATTGG	COPB2	ENSG00000184432	0.11292097273178	[]	[]	3	hSpCas9	negative selection	2583661
139378041	139378064	3	+	27260157	DLD1	viability	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.37543692037016	[]	[]	-9	hSpCas9	negative selection	2585803
139389543	139389566	3	-	27260157	DLD1	viability	TGGACCGACGCAGCCATGGTAGG	COPB2	ENSG00000184432	-3.3871780334469	[]	[]	-9	hSpCas9	negative selection	2587051
139373714	139373737	3	-	27260157	DLD1	viability	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-3.82409893544893	[]	[]	-9	hSpCas9	negative selection	2606656
139373728	139373751	3	-	27260157	DLD1	viability	AATGGAGAGGGTATGGTGCGTGG	COPB2	ENSG00000184432	-2.76207829013921	[]	[]	-9	hSpCas9	negative selection	2612227
139389519	139389542	3	+	27260157	DLD1	viability	CCGCTCCCTTCTACGGGATCTGG	COPB2	ENSG00000184432	0.240706345723316	[]	[]	4	hSpCas9	negative selection	2614722
139389576	139389599	3	-	27260157	DLD1	viability	GAGTAGCCGGTAACAAACGAGGG	COPB2	ENSG00000184432	-0.491208902963612	[]	[]	-4	hSpCas9	negative selection	2615658
139379411	139379434	3	+	27260157	DLD1	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.913687342711886	[]	[]	9	hSpCas9	negative selection	2616235
139379055	139379078	3	+	27260157	DLD1	viability	GTTAGAATGAAAGGCTGGGTTGG	COPB2	ENSG00000184432	-1.88257638596002	[]	[]	-8	hSpCas9	negative selection	2619572
139389628	139389651	3	+	27260157	DLD1	viability	GACCGTCAGACTGACTGACGTGG	COPB2	ENSG00000184432	-0.368377481615686	[]	[]	-3	hSpCas9	negative selection	2619583
139373400	139373423	3	-	27260157	DLD1	viability	TTTCTTTCAGCTTGGTCGGGAGG	COPB2	ENSG00000184432	-0.167149838196382	[]	[]	-1	hSpCas9	negative selection	2623362
139373694	139373717	3	-	27260157	DLD1	viability	GGGTCAAACAATGTCGCTTTGGG	COPB2	ENSG00000184432	-2.37053800170964	[]	[]	-9	hSpCas9	negative selection	2623900
139389517	139389540	3	-	27260157	DLD1	viability	AGATCCCGTAGAAGGGAGCGGGG	COPB2	ENSG00000184432	0.109837222215867	[]	[]	3	hSpCas9	negative selection	2647617
139375494	139375517	3	+	27260157	HT1080	viability	GGTCATCTGCACCTGAAATGAGG	COPB2	ENSG00000184432	-2.46886930334037	[]	[]	-9	hSpCas9	negative selection	2651177
139373755	139373778	3	+	27260157	HT1080	viability	AATTCAGTGTGCTCTCAAGCCGG	COPB2	ENSG00000184432	-2.89349910936735	[]	[]	-9	hSpCas9	negative selection	2652374
139389638	139389661	3	+	27260157	HT1080	viability	CTGACTGACGTGGAACTTCCGGG	COPB2	ENSG00000184432	1.53118249327564	[]	[]	9	hSpCas9	negative selection	2653148
139389656	139389679	3	-	27260157	HT1080	viability	CTATCGCGAGAATCGGCTCCCGG	COPB2	ENSG00000184432	-0.604786810088547	[]	[]	-8	hSpCas9	negative selection	2653792
139389614	139389637	3	-	27260157	HT1080	viability	CTGACGGTCAGTGGATCGGTGGG	COPB2	ENSG00000184432	-2.35912423435765	[]	[]	-9	hSpCas9	negative selection	2657658
139389570	139389593	3	+	27260157	HT1080	viability	CGGGAACCCTCGTTTGTTACCGG	COPB2	ENSG00000184432	-0.857600970660815	[]	[]	-8	hSpCas9	negative selection	2657872
139375505	139375528	3	-	27260157	HT1080	viability	GACAAGCCATACCTCATTTCAGG	COPB2	ENSG00000184432	-2.51025832930732	[]	[]	-9	hSpCas9	negative selection	2658331
139389563	139389586	3	-	27260157	HT1080	viability	CAAACGAGGGTTCCCGGGATTGG	COPB2	ENSG00000184432	-0.32443327019193	[]	[]	-7	hSpCas9	negative selection	2659791
139378041	139378064	3	+	27260157	HT1080	viability	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.30480753911286	[]	[]	-9	hSpCas9	negative selection	2661933
139389543	139389566	3	-	27260157	HT1080	viability	TGGACCGACGCAGCCATGGTAGG	COPB2	ENSG00000184432	-3.25498145751849	[]	[]	-9	hSpCas9	negative selection	2663181
139373714	139373737	3	-	27260157	HT1080	viability	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-3.2409821005376	[]	[]	-9	hSpCas9	negative selection	2682786
139373728	139373751	3	-	27260157	HT1080	viability	AATGGAGAGGGTATGGTGCGTGG	COPB2	ENSG00000184432	-2.19241006799854	[]	[]	-9	hSpCas9	negative selection	2688357
139389519	139389542	3	+	27260157	HT1080	viability	CCGCTCCCTTCTACGGGATCTGG	COPB2	ENSG00000184432	-0.695627242992158	[]	[]	-8	hSpCas9	negative selection	2690852
139389576	139389599	3	-	27260157	HT1080	viability	GAGTAGCCGGTAACAAACGAGGG	COPB2	ENSG00000184432	-0.836233303053483	[]	[]	-8	hSpCas9	negative selection	2691788
139379411	139379434	3	+	27260157	HT1080	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.02102812469402	[]	[]	8	hSpCas9	negative selection	2692365
139379055	139379078	3	+	27260157	HT1080	viability	GTTAGAATGAAAGGCTGGGTTGG	COPB2	ENSG00000184432	-1.98174337873741	[]	[]	-9	hSpCas9	negative selection	2695702
139389628	139389651	3	+	27260157	HT1080	viability	GACCGTCAGACTGACTGACGTGG	COPB2	ENSG00000184432	-0.0286330081733633	[]	[]	0	hSpCas9	negative selection	2695713
139373400	139373423	3	-	27260157	HT1080	viability	TTTCTTTCAGCTTGGTCGGGAGG	COPB2	ENSG00000184432	0.108251247216177	[]	[]	1	hSpCas9	negative selection	2699492
139373694	139373717	3	-	27260157	HT1080	viability	GGGTCAAACAATGTCGCTTTGGG	COPB2	ENSG00000184432	-2.21262013881221	[]	[]	-9	hSpCas9	negative selection	2700030
139389517	139389540	3	-	27260157	HT1080	viability	AGATCCCGTAGAAGGGAGCGGGG	COPB2	ENSG00000184432	0.343197119050135	[]	[]	3	hSpCas9	negative selection	2723747
139375494	139375517	3	+	27260157	MKN45	viability	GGTCATCTGCACCTGAAATGAGG	COPB2	ENSG00000184432	-3.62469656679089	[]	[]	-9	hSpCas9	negative selection	2727307
139373755	139373778	3	+	27260157	MKN45	viability	AATTCAGTGTGCTCTCAAGCCGG	COPB2	ENSG00000184432	-1.72143009949367	[]	[]	-9	hSpCas9	negative selection	2728504
139389638	139389661	3	+	27260157	MKN45	viability	CTGACTGACGTGGAACTTCCGGG	COPB2	ENSG00000184432	0.915603738419286	[]	[]	8	hSpCas9	negative selection	2729278
139389656	139389679	3	-	27260157	MKN45	viability	CTATCGCGAGAATCGGCTCCCGG	COPB2	ENSG00000184432	-0.963544680869131	[]	[]	-7	hSpCas9	negative selection	2729922
139389614	139389637	3	-	27260157	MKN45	viability	CTGACGGTCAGTGGATCGGTGGG	COPB2	ENSG00000184432	-1.5576585834378	[]	[]	-9	hSpCas9	negative selection	2733788
139389570	139389593	3	+	27260157	MKN45	viability	CGGGAACCCTCGTTTGTTACCGG	COPB2	ENSG00000184432	-0.438703332173213	[]	[]	-6	hSpCas9	negative selection	2734002
139375505	139375528	3	-	27260157	MKN45	viability	GACAAGCCATACCTCATTTCAGG	COPB2	ENSG00000184432	-2.4425300668199	[]	[]	-9	hSpCas9	negative selection	2734461
139389563	139389586	3	-	27260157	MKN45	viability	CAAACGAGGGTTCCCGGGATTGG	COPB2	ENSG00000184432	0.521634943194968	[]	[]	6	hSpCas9	negative selection	2735921
139378041	139378064	3	+	27260157	MKN45	viability	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.17137193301051	[]	[]	-9	hSpCas9	negative selection	2738063
139389543	139389566	3	-	27260157	MKN45	viability	TGGACCGACGCAGCCATGGTAGG	COPB2	ENSG00000184432	-1.80548484196668	[]	[]	-9	hSpCas9	negative selection	2739311
139373714	139373737	3	-	27260157	MKN45	viability	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-2.60652389958497	[]	[]	-9	hSpCas9	negative selection	2758916
139373728	139373751	3	-	27260157	MKN45	viability	AATGGAGAGGGTATGGTGCGTGG	COPB2	ENSG00000184432	-2.42861038211159	[]	[]	-9	hSpCas9	negative selection	2764487
139389519	139389542	3	+	27260157	MKN45	viability	CCGCTCCCTTCTACGGGATCTGG	COPB2	ENSG00000184432	-0.046740055001322	[]	[]	0	hSpCas9	negative selection	2766982
139389576	139389599	3	-	27260157	MKN45	viability	GAGTAGCCGGTAACAAACGAGGG	COPB2	ENSG00000184432	-0.0995367988720569	[]	[]	0	hSpCas9	negative selection	2767918
139379411	139379434	3	+	27260157	MKN45	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.66891367642665	[]	[]	7	hSpCas9	negative selection	2768495
139379055	139379078	3	+	27260157	MKN45	viability	GTTAGAATGAAAGGCTGGGTTGG	COPB2	ENSG00000184432	-2.0312214388069	[]	[]	-9	hSpCas9	negative selection	2771832
139389628	139389651	3	+	27260157	MKN45	viability	GACCGTCAGACTGACTGACGTGG	COPB2	ENSG00000184432	0.12007655275621	[]	[]	4	hSpCas9	negative selection	2771843
139373400	139373423	3	-	27260157	MKN45	viability	TTTCTTTCAGCTTGGTCGGGAGG	COPB2	ENSG00000184432	0.82070789132606	[]	[]	8	hSpCas9	negative selection	2775622
139373694	139373717	3	-	27260157	MKN45	viability	GGGTCAAACAATGTCGCTTTGGG	COPB2	ENSG00000184432	-1.02029313700883	[]	[]	-8	hSpCas9	negative selection	2776160
139389517	139389540	3	-	27260157	MKN45	viability	AGATCCCGTAGAAGGGAGCGGGG	COPB2	ENSG00000184432	0.072480993408699	[]	[]	0	hSpCas9	negative selection	2799877
139375494	139375517	3	+	27260157	RKO	viability	GGTCATCTGCACCTGAAATGAGG	COPB2	ENSG00000184432	-3.6020862613186	[]	[]	-9	hSpCas9	negative selection	2803437
139373755	139373778	3	+	27260157	RKO	viability	AATTCAGTGTGCTCTCAAGCCGG	COPB2	ENSG00000184432	-1.46558385591488	[]	[]	-8	hSpCas9	negative selection	2804634
139389638	139389661	3	+	27260157	RKO	viability	CTGACTGACGTGGAACTTCCGGG	COPB2	ENSG00000184432	0.719730952861508	[]	[]	8	hSpCas9	negative selection	2805408
139389656	139389679	3	-	27260157	RKO	viability	CTATCGCGAGAATCGGCTCCCGG	COPB2	ENSG00000184432	-0.63670615425233	[]	[]	-7	hSpCas9	negative selection	2806052
139389614	139389637	3	-	27260157	RKO	viability	CTGACGGTCAGTGGATCGGTGGG	COPB2	ENSG00000184432	-0.876916254535889	[]	[]	-8	hSpCas9	negative selection	2809918
139389570	139389593	3	+	27260157	RKO	viability	CGGGAACCCTCGTTTGTTACCGG	COPB2	ENSG00000184432	-0.62140564847522	[]	[]	-7	hSpCas9	negative selection	2810132
139375505	139375528	3	-	27260157	RKO	viability	GACAAGCCATACCTCATTTCAGG	COPB2	ENSG00000184432	-2.09355133407266	[]	[]	-9	hSpCas9	negative selection	2810591
139389563	139389586	3	-	27260157	RKO	viability	CAAACGAGGGTTCCCGGGATTGG	COPB2	ENSG00000184432	-0.49653298853344	[]	[]	-6	hSpCas9	negative selection	2812051
139378041	139378064	3	+	27260157	RKO	viability	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.34098019421858	[]	[]	-9	hSpCas9	negative selection	2814193
139389543	139389566	3	-	27260157	RKO	viability	TGGACCGACGCAGCCATGGTAGG	COPB2	ENSG00000184432	-3.07165691452023	[]	[]	-9	hSpCas9	negative selection	2815441
139373714	139373737	3	-	27260157	RKO	viability	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-2.41071978450506	[]	[]	-9	hSpCas9	negative selection	2835046
139373728	139373751	3	-	27260157	RKO	viability	AATGGAGAGGGTATGGTGCGTGG	COPB2	ENSG00000184432	-2.66052485176302	[]	[]	-9	hSpCas9	negative selection	2840617
139389519	139389542	3	+	27260157	RKO	viability	CCGCTCCCTTCTACGGGATCTGG	COPB2	ENSG00000184432	0.263750172809399	[]	[]	1	hSpCas9	negative selection	2843112
139389576	139389599	3	-	27260157	RKO	viability	GAGTAGCCGGTAACAAACGAGGG	COPB2	ENSG00000184432	-0.874899430553756	[]	[]	-8	hSpCas9	negative selection	2844048
139379411	139379434	3	+	27260157	RKO	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.12768617613903	[]	[]	9	hSpCas9	negative selection	2844625
139379055	139379078	3	+	27260157	RKO	viability	GTTAGAATGAAAGGCTGGGTTGG	COPB2	ENSG00000184432	-2.12482286103865	[]	[]	-9	hSpCas9	negative selection	2847962
139389628	139389651	3	+	27260157	RKO	viability	GACCGTCAGACTGACTGACGTGG	COPB2	ENSG00000184432	-1.05669952205609	[]	[]	-8	hSpCas9	negative selection	2847973
139373400	139373423	3	-	27260157	RKO	viability	TTTCTTTCAGCTTGGTCGGGAGG	COPB2	ENSG00000184432	0.680076842778041	[]	[]	7	hSpCas9	negative selection	2851752
139373694	139373717	3	-	27260157	RKO	viability	GGGTCAAACAATGTCGCTTTGGG	COPB2	ENSG00000184432	-3.32303740117558	[]	[]	-9	hSpCas9	negative selection	2852290
139389517	139389540	3	-	27260157	RKO	viability	AGATCCCGTAGAAGGGAGCGGGG	COPB2	ENSG00000184432	0.116902419493399	[]	[]	0	hSpCas9	negative selection	2876007
139375494	139375517	3	+	27260157	SF268	viability	GGTCATCTGCACCTGAAATGAGG	COPB2	ENSG00000184432	-4.41363012217137	[]	[]	-9	hSpCas9	negative selection	2879567
139373755	139373778	3	+	27260157	SF268	viability	AATTCAGTGTGCTCTCAAGCCGG	COPB2	ENSG00000184432	-2.22506600384291	[]	[]	-9	hSpCas9	negative selection	2880764
139389638	139389661	3	+	27260157	SF268	viability	CTGACTGACGTGGAACTTCCGGG	COPB2	ENSG00000184432	1.13946599610412	[]	[]	9	hSpCas9	negative selection	2881538
139389656	139389679	3	-	27260157	SF268	viability	CTATCGCGAGAATCGGCTCCCGG	COPB2	ENSG00000184432	-0.0872413837090098	[]	[]	0	hSpCas9	negative selection	2882182
139389614	139389637	3	-	27260157	SF268	viability	CTGACGGTCAGTGGATCGGTGGG	COPB2	ENSG00000184432	-1.50935446110253	[]	[]	-8	hSpCas9	negative selection	2886048
139389570	139389593	3	+	27260157	SF268	viability	CGGGAACCCTCGTTTGTTACCGG	COPB2	ENSG00000184432	-0.00263637121215633	[]	[]	0	hSpCas9	negative selection	2886262
139375505	139375528	3	-	27260157	SF268	viability	GACAAGCCATACCTCATTTCAGG	COPB2	ENSG00000184432	-2.97526423174828	[]	[]	-9	hSpCas9	negative selection	2886721
139389563	139389586	3	-	27260157	SF268	viability	CAAACGAGGGTTCCCGGGATTGG	COPB2	ENSG00000184432	-1.00173840055764	[]	[]	-7	hSpCas9	negative selection	2888181
139378041	139378064	3	+	27260157	SF268	viability	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.8127719309989	[]	[]	-9	hSpCas9	negative selection	2890323
139389543	139389566	3	-	27260157	SF268	viability	TGGACCGACGCAGCCATGGTAGG	COPB2	ENSG00000184432	-3.55426343679576	[]	[]	-9	hSpCas9	negative selection	2891571
139373714	139373737	3	-	27260157	SF268	viability	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-4.86021253220093	[]	[]	-9	hSpCas9	negative selection	2911176
139373728	139373751	3	-	27260157	SF268	viability	AATGGAGAGGGTATGGTGCGTGG	COPB2	ENSG00000184432	-2.65422906463345	[]	[]	-9	hSpCas9	negative selection	2916747
139389519	139389542	3	+	27260157	SF268	viability	CCGCTCCCTTCTACGGGATCTGG	COPB2	ENSG00000184432	0.488205889966903	[]	[]	7	hSpCas9	negative selection	2919242
139389576	139389599	3	-	27260157	SF268	viability	GAGTAGCCGGTAACAAACGAGGG	COPB2	ENSG00000184432	0.134231669420586	[]	[]	0	hSpCas9	negative selection	2920178
139379411	139379434	3	+	27260157	SF268	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.425876827717869	[]	[]	4	hSpCas9	negative selection	2920755
139379055	139379078	3	+	27260157	SF268	viability	GTTAGAATGAAAGGCTGGGTTGG	COPB2	ENSG00000184432	-3.31982404854478	[]	[]	-9	hSpCas9	negative selection	2924092
139389628	139389651	3	+	27260157	SF268	viability	GACCGTCAGACTGACTGACGTGG	COPB2	ENSG00000184432	-0.162762430523477	[]	[]	-1	hSpCas9	negative selection	2924103
139373400	139373423	3	-	27260157	SF268	viability	TTTCTTTCAGCTTGGTCGGGAGG	COPB2	ENSG00000184432	0.54256443009548	[]	[]	8	hSpCas9	negative selection	2927882
139373694	139373717	3	-	27260157	SF268	viability	GGGTCAAACAATGTCGCTTTGGG	COPB2	ENSG00000184432	-3.72933963152466	[]	[]	-9	hSpCas9	negative selection	2928420
139389517	139389540	3	-	27260157	SF268	viability	AGATCCCGTAGAAGGGAGCGGGG	COPB2	ENSG00000184432	0.847057591733988	[]	[]	9	hSpCas9	negative selection	2952137
139383352	139383375	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCTGCATCCTACAGAGCCATGG	COPB2	ENSG00000184432	-1.058480158937004	[1,2]	[0,0]	-9	hSpCas9	positive selection	2980592
139373224	139373247	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTGTGCTGAATAGTCTGAGGG	COPB2	ENSG00000184432	0.10847528081538793	[2,2]	[3,0]	2	hSpCas9	positive selection	2980593
139373294	139373317	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGATGCTGAAATTAAAGATGG	COPB2	ENSG00000184432	-0.553151831701709	[3,4]	[1,1]	-7	hSpCas9	positive selection	2980594
139369355	139369378	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-0.6140763287132355	[2,3]	[2,0]	-7	hSpCas9	positive selection	2980595
139383352	139383375	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCTGCATCCTACAGAGCCATGG	COPB2	ENSG00000184432	1.1826961649530197	[1,1]	[3,2]	9	hSpCas9	positive selection	3048450
139373224	139373247	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTGTGCTGAATAGTCTGAGGG	COPB2	ENSG00000184432	-0.3036911740793271	[2,2]	[0,0]	-4	hSpCas9	positive selection	3048451
139373294	139373317	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGATGCTGAAATTAAAGATGG	COPB2	ENSG00000184432	-0.8905581523155611	[3,3]	[1,0]	-9	hSpCas9	positive selection	3048452
139369355	139369378	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-0.3875227091088373	[2,2]	[2,0]	-6	hSpCas9	positive selection	3048453
139379411	139379434		+	24336571	A375	resistance to PLX after 7 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.1934868286770891	[4,5]	[6,4]	6	hSpCas9	positive selection	3106852
139383375	139383398		-	24336571	A375	resistance to PLX after 7 days	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	0.0646061798527906	[5,3]	[3,5]	2	hSpCas9	positive selection	3106853
139383413	139383436		+	24336571	A375	resistance to PLX after 7 days	CTTTTGATATCAAGTCGCAGAGG	COPB2	ENSG00000184432	0.09410391684474258	[12,11]	[12,12]	3	hSpCas9	positive selection	3106854
139379411	139379434		+	24336571	A375	resistance to PLX after 14 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.2991220462259081	[3,7]	[2,2]	3	hSpCas9	positive selection	3164645
139383375	139383398		-	24336571	A375	resistance to PLX after 14 days	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	0.7608667515517729	[1,2]	[1,1]	6	hSpCas9	positive selection	3164646
139383413	139383436		+	24336571	A375	resistance to PLX after 14 days	CTTTTGATATCAAGTCGCAGAGG	COPB2	ENSG00000184432	-0.6041364234868614	[15,18]	[4,4]	-7	hSpCas9	positive selection	3164647
139379411	139379434		+	24336571	A375	viability after 7 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-1.3211248491470187	[14]	[4,5]	-9	hSpCas9	negative selection	3222438
139383375	139383398		-	24336571	A375	viability after 7 days	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.531053724123614	[15]	[5,3]	-9	hSpCas9	negative selection	3222439
139383413	139383436		+	24336571	A375	viability after 7 days	CTTTTGATATCAAGTCGCAGAGG	COPB2	ENSG00000184432	-0.09178328877649025	[13]	[12,11]	-1	hSpCas9	negative selection	3222440
139379411	139379434		+	24336571	A375	viability after 14 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-1.2458443615395431	[14]	[3,7]	-9	hSpCas9	negative selection	3280231
139383375	139383398		-	24336571	A375	viability after 14 days	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-2.336850445488573	[15]	[1,2]	-9	hSpCas9	negative selection	3280232
139383413	139383436		+	24336571	A375	viability after 14 days	CTTTTGATATCAAGTCGCAGAGG	COPB2	ENSG00000184432	0.4404957296881291	[13]	[15,18]	5	hSpCas9	negative selection	3280233
139379411	139379434	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.4069248534915242	[98,131]	[0,0]	2	hSpCas9	positive selection	3344152
139383375	139383398	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	3.351286359665486	[115,138]	[0,15]	9	hSpCas9	positive selection	3344153
139383335	139383358	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	3.4979057664519333	[19,6]	[0,0]	9	hSpCas9	positive selection	3344154
139375575	139375598	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	0.6574133692587072	[96,96]	[0,0]	3	hSpCas9	positive selection	3363379
139379404	139379427	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.6130385081375694	[233,233]	[0,0]	-4	hSpCas9	positive selection	3363380
139375568	139375591	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	1.8310614567437373	[42,42]	[0,0]	7	hSpCas9	positive selection	3363381
139383352	139383375	3	-	26780180	HT29	viability (Avana library 4 designs)	ATCTGCATCCTACAGAGCCATGG	COPB2	ENSG00000184432	3.89437135861411	[]	[]	9	hSpCas9	negative selection	3417054
139373223	139373246	3	+	26780180	HT29	viability (Avana library 4 designs)	GATTGTGCTGAATAGTCTGAGGG	COPB2	ENSG00000184432	6.00329145209107	[]	[]	9	hSpCas9	negative selection	3417055
139373294	139373317	3	-	26780180	HT29	viability (Avana library 4 designs)	GGAGATGCTGAAATTAAAGATGG	COPB2	ENSG00000184432	2.98978504114598	[]	[]	8	hSpCas9	negative selection	3417056
139369355	139369378	3	-	26780180	HT29	viability (Avana library 4 designs)	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	7.15507192892482	[]	[]	9	hSpCas9	negative selection	3417057
139373223	139373246	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATTGTGCTGAATAGTCTGAGGG	COPB2	ENSG00000184432	-9.01358539683068	[]	[]	-7	hSpCas9	negative selection	3494879
139369355	139369378	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-18.0184064874901	[]	[]	-9	hSpCas9	negative selection	3494880
139383352	139383375	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCTGCATCCTACAGAGCCATGG	COPB2	ENSG00000184432	-17.775939668215	[]	[]	-9	hSpCas9	negative selection	3494881
139373294	139373317	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGATGCTGAAATTAAAGATGG	COPB2	ENSG00000184432	-14.4654744011323	[]	[]	-8	hSpCas9	negative selection	3494882
139373212	139373235	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCAGCACAATCCTAATGGGCGG	COPB2	ENSG00000184432	-18.5172659161069	[]	[]	-9	hSpCas9	negative selection	3494883
139373316	139373339	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-4.73906424688445	[]	[]	-5	hSpCas9	negative selection	3494884
139373223	139373246	3	+	26780180	A375	viability (Avana lentiGuide)	GATTGTGCTGAATAGTCTGAGGG	COPB2	ENSG00000184432	26.7153386557857	[]	[]	9	hSpCas9	negative selection	3603538
139369355	139369378	3	-	26780180	A375	viability (Avana lentiGuide)	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	29.9168872777945	[]	[]	9	hSpCas9	negative selection	3603539
139383352	139383375	3	-	26780180	A375	viability (Avana lentiGuide)	ATCTGCATCCTACAGAGCCATGG	COPB2	ENSG00000184432	22.1097258783824	[]	[]	9	hSpCas9	negative selection	3603540
139373294	139373317	3	-	26780180	A375	viability (Avana lentiGuide)	GGAGATGCTGAAATTAAAGATGG	COPB2	ENSG00000184432	15.1467188645415	[]	[]	8	hSpCas9	negative selection	3603541
139373212	139373235	3	-	26780180	A375	viability (Avana lentiGuide)	TTCAGCACAATCCTAATGGGCGG	COPB2	ENSG00000184432	27.8986555432233	[]	[]	9	hSpCas9	negative selection	3603542
139373316	139373339	3	-	26780180	A375	viability (Avana lentiGuide)	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	17.1279049789399	[]	[]	8	hSpCas9	negative selection	3603543
139373223	139373246	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTGTGCTGAATAGTCTGAGGG	COPB2	ENSG00000184432	-0.7262226944188539	[5]	[3,2]	-8	hSpCas9	positive selection	3712197
139369355	139369378	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-2.41544004806045	[7]	[0,0]	-9	hSpCas9	positive selection	3712198
139383352	139383375	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCTGCATCCTACAGAGCCATGG	COPB2	ENSG00000184432	-1.2418049047769426	[5]	[1,1]	-9	hSpCas9	positive selection	3712199
139373294	139373317	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGATGCTGAAATTAAAGATGG	COPB2	ENSG00000184432	-0.6214987372796098	[6]	[3,3]	-7	hSpCas9	positive selection	3712200
139373212	139373235	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCAGCACAATCCTAATGGGCGG	COPB2	ENSG00000184432	-1.7466498571951359	[5]	[1,0]	-9	hSpCas9	positive selection	3712201
139373316	139373339	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.1449763632183556	[4]	[1,1]	-9	hSpCas9	positive selection	3712202
139373223	139373246	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTGTGCTGAATAGTCTGAGGG	COPB2	ENSG00000184432	-0.7764910875143093	[5]	[1,2]	-7	hSpCas9	positive selection	3820804
139369355	139369378	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-1.425720118379371	[6]	[1,0]	-9	hSpCas9	positive selection	3820805
139383352	139383375	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCTGCATCCTACAGAGCCATGG	COPB2	ENSG00000184432	-1.351414978929532	[4]	[0,0]	-9	hSpCas9	positive selection	3820806
139373294	139373317	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGATGCTGAAATTAAAGATGG	COPB2	ENSG00000184432	-0.2770200576641967	[5]	[3,3]	-4	hSpCas9	positive selection	3820807
139373212	139373235	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCAGCACAATCCTAATGGGCGG	COPB2	ENSG00000184432	-1.690686760388717	[5]	[0,0]	-9	hSpCas9	positive selection	3820808
139373316	139373339	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.6649727729514097	[4]	[0,0]	-9	hSpCas9	positive selection	3820809
139379411	139379434	3	+	26780180	A375	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.835809480279511	[]	[]	3	hSpCas9	negative selection	3928821
139383375	139383398	3	-	26780180	A375	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	1.86680912758286	[]	[]	9	hSpCas9	negative selection	3928822
139379404	139379427	3	-	26780180	A375	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	1.67129022877096	[]	[]	9	hSpCas9	negative selection	3928823
139383335	139383358	3	+	26780180	A375	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	2.0054034551808	[]	[]	9	hSpCas9	negative selection	3928824
139375568	139375591	3	+	26780180	A375	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	1.48068513479249	[]	[]	8	hSpCas9	negative selection	3928825
139375575	139375598	3	-	26780180	A375	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	2.29964067154172	[]	[]	9	hSpCas9	negative selection	3928826
139379411	139379434	3	+	26780180	HT29	viability (GeCKOv2 library)	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.822214572741017	[]	[]	3	hSpCas9	negative selection	4036787
139383375	139383398	3	-	26780180	HT29	viability (GeCKOv2 library)	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	1.93402371540867	[]	[]	9	hSpCas9	negative selection	4036788
139379404	139379427	3	-	26780180	HT29	viability (GeCKOv2 library)	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	2.28408732890709	[]	[]	9	hSpCas9	negative selection	4036789
139383335	139383358	3	+	26780180	HT29	viability (GeCKOv2 library)	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	2.80585021294877	[]	[]	9	hSpCas9	negative selection	4036790
139375568	139375591	3	+	26780180	HT29	viability (GeCKOv2 library)	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	1.4900687764488	[]	[]	7	hSpCas9	negative selection	4036791
139375575	139375598	3	-	26780180	HT29	viability (GeCKOv2 library)	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	2.20379741953996	[]	[]	9	hSpCas9	negative selection	4036792
139379411	139379434	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-0.08508295561847248	[3]	[2,1]	-2	hSpCas9	positive selection	4129062
139383375	139383398	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.23575328243821503	[1]	[0,0]	-5	hSpCas9	positive selection	4129063
139383413	139383436	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTTGATATCAAGTCGCAGAGG	COPB2	ENSG00000184432	-0.009925077682423011	[3]	[1,2]	0	hSpCas9	positive selection	4129064
139379411	139379434	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.9109060540222275	[3]	[1,2,2,3]	6	hSpCas9	positive selection	4193084
139383375	139383398	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	0.8321777680417168	[3]	[0,1,0,4]	5	hSpCas9	positive selection	4193085
139383413	139383436	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTTGATATCAAGTCGCAGAGG	COPB2	ENSG00000184432	0.855012308019843	[4]	[0,0,5,4]	5	hSpCas9	positive selection	4193086
139379411	139379434	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-0.11271779825626604	[2]	[3,0]	-2	hSpCas9	positive selection	4264394
139383375	139383398	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.28558806849701485	[3]	[2,1]	-5	hSpCas9	positive selection	4264395
139383335	139383358	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.4694134359212256	[3]	[0,0]	-9	hSpCas9	positive selection	4264396
139375575	139375598	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.22373478970845842	[3]	[2,1]	-4	hSpCas9	positive selection	4328665
139379404	139379427	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.011962165035271727	[3]	[2,2]	0	hSpCas9	positive selection	4328666
139375568	139375591	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.35643084244070267	[2]	[1,0]	-6	hSpCas9	positive selection	4328667
139369353	139369375	3	+	27760321	OCIAML3	viability	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-0.13597095715604812	[243,171]	[112,189]	-1	hSpCas9	negative selection	4391064
139373715	139373737	3	-	27760321	OCIAML3	viability	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-2.4292895988325727	[433,331]	[62,44]	-9	hSpCas9	negative selection	4391065
139373760	139373782	3	+	27760321	OCIAML3	viability	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-1.2479120616068597	[714,672]	[160,316]	-8	hSpCas9	negative selection	4391066
139378042	139378064	3	+	27760321	OCIAML3	viability	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-1.0747134572227135	[164,198]	[76,56]	-7	hSpCas9	negative selection	4391067
139379412	139379434	3	+	27760321	OCIAML3	viability	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-0.3671262641303001	[736,638]	[350,500]	-4	hSpCas9	negative selection	4391068
139369353	139369375	3	+	27760321	OCIAML2	viability	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-2.215648220960121	[243,171]	[18,57]	-9	hSpCas9	negative selection	4474527
139373715	139373737	3	-	27760321	OCIAML2	viability	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-0.880997744606034	[433,331]	[194,129]	-7	hSpCas9	negative selection	4474528
139373760	139373782	3	+	27760321	OCIAML2	viability	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-1.7267792358983187	[714,672]	[142,204]	-9	hSpCas9	negative selection	4474529
139378042	139378064	3	+	27760321	OCIAML2	viability	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.8687419764351354	[164,198]	[6,37]	-9	hSpCas9	negative selection	4474530
139379412	139379434	3	+	27760321	OCIAML2	viability	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-0.5609104346181422	[736,638]	[371,381]	-6	hSpCas9	negative selection	4474531
139369353	139369375	3	+	27760321	MV411	viability	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-1.090608889205687	[243,171]	[0,157]	-6	hSpCas9	negative selection	4557990
139373715	139373737	3	-	27760321	MV411	viability	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-1.7931977775565673	[433,331]	[31,132]	-8	hSpCas9	negative selection	4557991
139373760	139373782	3	+	27760321	MV411	viability	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-0.9157697432895443	[714,672]	[178,338]	-6	hSpCas9	negative selection	4557992
139378042	139378064	3	+	27760321	MV411	viability	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-0.28399868197010325	[164,198]	[4,241]	-2	hSpCas9	negative selection	4557993
139379412	139379434	3	+	27760321	MV411	viability	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.6245925178991855	[736,638]	[204,1438]	4	hSpCas9	negative selection	4557994
139369353	139369375	3	+	27760321	HL60	viability	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-2.254390588400546	[243,171]	[25,44]	-9	hSpCas9	negative selection	4641453
139373715	139373737	3	-	27760321	HL60	viability	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-2.4349817050811176	[433,331]	[37,77]	-9	hSpCas9	negative selection	4641454
139373760	139373782	3	+	27760321	HL60	viability	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-0.4193202177568638	[714,672]	[432,414]	-5	hSpCas9	negative selection	4641455
139378042	139378064	3	+	27760321	HL60	viability	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-1.8277876792563554	[164,198]	[36,47]	-9	hSpCas9	negative selection	4641456
139379412	139379434	3	+	27760321	HL60	viability	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-0.9352772571772741	[736,638]	[297,287]	-7	hSpCas9	negative selection	4641457
139369353	139369375	3	+	27760321	HT1080	viability	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-5.929411187823385	[171,133]	[0,0]	-9	hSpCas9	negative selection	4724916
139373715	139373737	3	-	27760321	HT1080	viability	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-2.2750536129875853	[331,258]	[9,39]	-6	hSpCas9	negative selection	4724917
139373760	139373782	3	+	27760321	HT1080	viability	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-5.313589793289699	[672,524]	[5,5]	-8	hSpCas9	negative selection	4724918
139378042	139378064	3	+	27760321	HT1080	viability	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-6.139608803224139	[198,154]	[0,0]	-9	hSpCas9	negative selection	4724919
139379412	139379434	3	+	27760321	HT1080	viability	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-5.874381865712286	[638,498]	[0,6]	-8	hSpCas9	negative selection	4724920
139369353	139369375	3	+	27760321	HT29	viability after 7 days	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-2.1218870172051743	[171,133]	[23,47,59]	-9	hSpCas9	negative selection	4808379
139373715	139373737	3	-	27760321	HT29	viability after 7 days	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-1.940384688898949	[331,258]	[69,101,119]	-9	hSpCas9	negative selection	4808380
139373760	139373782	3	+	27760321	HT29	viability after 7 days	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-2.3542660258009804	[672,524]	[186,61,205]	-9	hSpCas9	negative selection	4808381
139378042	139378064	3	+	27760321	HT29	viability after 7 days	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.153549204386004	[198,154]	[23,58,65]	-9	hSpCas9	negative selection	4808382
139379412	139379434	3	+	27760321	HT29	viability after 7 days	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-0.7943498979585402	[638,498]	[345,514,393]	-8	hSpCas9	negative selection	4808383
139369353	139369375	3	+	27760321	HT29	viability after 25 days	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-4.107004061831001	[171,133]	[1,0,29]	-9	hSpCas9	negative selection	4891842
139373715	139373737	3	-	27760321	HT29	viability after 25 days	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-2.040683803091717	[331,258]	[28,124,96]	-8	hSpCas9	negative selection	4891843
139373760	139373782	3	+	27760321	HT29	viability after 25 days	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-3.476372404036252	[672,524]	[40,28,121]	-9	hSpCas9	negative selection	4891844
139378042	139378064	3	+	27760321	HT29	viability after 25 days	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.974421304457955	[198,154]	[17,0,19]	-9	hSpCas9	negative selection	4891845
139379412	139379434	3	+	27760321	HT29	viability after 25 days	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-3.622039243775572	[638,498]	[30,21,112]	-9	hSpCas9	negative selection	4891846
139369353	139369375	3	+	27760321	HT29	viability after 22 days	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-3.3694165390027386	[171,133]	[0,9,40]	-9	hSpCas9	negative selection	4975305
139373715	139373737	3	-	27760321	HT29	viability after 22 days	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-1.8754567455792397	[331,258]	[10,126,143]	-8	hSpCas9	negative selection	4975306
139373760	139373782	3	+	27760321	HT29	viability after 22 days	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-3.2538156581060207	[672,524]	[68,62,85]	-9	hSpCas9	negative selection	4975307
139378042	139378064	3	+	27760321	HT29	viability after 22 days	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-4.420659514988952	[198,154]	[1,2,23]	-9	hSpCas9	negative selection	4975308
139379412	139379434	3	+	27760321	HT29	viability after 22 days	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-3.3006148482626174	[638,498]	[56,28,114]	-9	hSpCas9	negative selection	4975309
139369353	139369375	3	+	27760321	HT29	viability after 19 days	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-7.450572032105955	[171,133]	[0,0,0]	-9	hSpCas9	negative selection	5058768
139373715	139373737	3	-	27760321	HT29	viability after 19 days	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-3.4045532057537535	[331,258]	[30,15,47]	-9	hSpCas9	negative selection	5058769
139373760	139373782	3	+	27760321	HT29	viability after 19 days	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-2.658423451312095	[672,524]	[16,59,233]	-8	hSpCas9	negative selection	5058770
139378042	139378064	3	+	27760321	HT29	viability after 19 days	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-5.014239127239106	[198,154]	[1,0,14]	-9	hSpCas9	negative selection	5058771
139379412	139379434	3	+	27760321	HT29	viability after 19 days	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-3.827598418995717	[638,498]	[51,36,48]	-9	hSpCas9	negative selection	5058772
139369353	139369375	3	+	27760321	HT29	viability after 16 days	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-2.914835337636836	[171,133]	[0,23,40]	-9	hSpCas9	negative selection	5142231
139373715	139373737	3	-	27760321	HT29	viability after 16 days	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-1.6460915856760943	[331,258]	[131,80,106]	-8	hSpCas9	negative selection	5142232
139373760	139373782	3	+	27760321	HT29	viability after 16 days	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-3.860779309921301	[672,524]	[105,8,29]	-9	hSpCas9	negative selection	5142233
139378042	139378064	3	+	27760321	HT29	viability after 16 days	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.4894451994518154	[198,154]	[38,13,1]	-9	hSpCas9	negative selection	5142234
139379412	139379434	3	+	27760321	HT29	viability after 16 days	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-2.8152736928706594	[638,498]	[151,95,28]	-9	hSpCas9	negative selection	5142235
139369353	139369375	3	+	27760321	HT29	viability after 13 days	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-2.737332673745586	[171,133]	[0,53,24]	-9	hSpCas9	negative selection	5225694
139373715	139373737	3	-	27760321	HT29	viability after 13 days	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-0.7544927378156783	[331,258]	[252,230,129]	-7	hSpCas9	negative selection	5225695
139373760	139373782	3	+	27760321	HT29	viability after 13 days	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-1.8228582921483307	[672,524]	[212,244,134]	-8	hSpCas9	negative selection	5225696
139378042	139378064	3	+	27760321	HT29	viability after 13 days	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-6.284454530411292	[198,154]	[3,2,0]	-9	hSpCas9	negative selection	5225697
139379412	139379434	3	+	27760321	HT29	viability after 13 days	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-2.18884489868104	[638,498]	[89,191,151]	-9	hSpCas9	negative selection	5225698
139369353	139369375	3	+	27760321	HT29	viability after 10 days	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-4.118093534810782	[171,133]	[28,2,0]	-9	hSpCas9	negative selection	5309157
139373715	139373737	3	-	27760321	HT29	viability after 10 days	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-2.196844454681762	[331,258]	[34,172,36]	-9	hSpCas9	negative selection	5309158
139373760	139373782	3	+	27760321	HT29	viability after 10 days	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-2.3333450418419805	[672,524]	[72,178,192]	-9	hSpCas9	negative selection	5309159
139378042	139378064	3	+	27760321	HT29	viability after 10 days	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.2291341671152107	[198,154]	[74,6,57]	-9	hSpCas9	negative selection	5309160
139379412	139379434	3	+	27760321	HT29	viability after 10 days	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-1.8111818910059903	[638,498]	[162,293,153]	-9	hSpCas9	negative selection	5309161
139369353	139369375	3	+	27760321	MOLM13	viability	AGCCGCCGTAGATACCTAAAGG	COPB2	ENSG00000184432	-2.44463610608347	[243,171]	[16,24]	-8	hSpCas9	negative selection	5392620
139373715	139373737	3	-	27760321	MOLM13	viability	GGTGCGTGGCCAGTCTAAGAGG	COPB2	ENSG00000184432	-4.949088117417148	[433,331]	[0,11]	-9	hSpCas9	negative selection	5392621
139373760	139373782	3	+	27760321	MOLM13	viability	AGTGTGCTCTCAAGCCGGTAGG	COPB2	ENSG00000184432	-1.954966634485575	[714,672]	[126,78]	-8	hSpCas9	negative selection	5392622
139378042	139378064	3	+	27760321	MOLM13	viability	TTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-4.809934576830525	[164,198]	[0,5]	-9	hSpCas9	negative selection	5392623
139379412	139379434	3	+	27760321	MOLM13	viability	CAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-2.009604034876528	[736,638]	[194,11]	-8	hSpCas9	negative selection	5392624
139389551	139389574	3	+	27661255	K562	viability	GGCTGCGTCGGTCCAATCCCGGG	COPB2	ENSG00000184432	-3.4207894640278056	[268,363]	[16,28]	-9	dCas9-KRAB	negative selection	5472219
139389265	139389288	3	-	27661255	K562	viability	GCAGTCTGCAGCGGGATCGGTGG	COPB2	ENSG00000184432	-1.4054734149030075	[1423,1175]	[489,310]	-9	dCas9-KRAB	negative selection	5472220
139389602	139389625	3	-	27661255	K562	viability	GGATCGGTGGGTTTATCTCAAGG	COPB2	ENSG00000184432	-2.509916057140802	[433,459]	[87,40]	-9	dCas9-KRAB	negative selection	5472221
139379411	139379434	3	+	27260156	BXPC3	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.334060102890406	[426]	[532,544,572,605]	7	hSpCas9	negative selection	5536854
139383375	139383398	3	-	27260156	BXPC3	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.5222383649742571	[906]	[581,571,819,681]	-8	hSpCas9	negative selection	5536855
139383335	139383358	3	+	27260156	BXPC3	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.7219670963980196	[463]	[131,107,165,190]	-9	hSpCas9	negative selection	5536856
139375575	139375598	3	-	27260156	BXPC3	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.7008331730476481	[812]	[336,677,470,624]	-8	hSpCas9	negative selection	5601125
139379404	139379427	3	-	27260156	BXPC3	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.01936022998322917	[600]	[514,605,553,838]	0	hSpCas9	negative selection	5601126
139375568	139375591	3	+	27260156	BXPC3	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.38521117069395516	[295]	[227,314,128,272]	-7	hSpCas9	negative selection	5601127
139379411	139379434	3	+	27260156	A673	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.2629872070071837	[426]	[689,537,615,626]	6	hSpCas9	negative selection	5658105
139383375	139383398	3	-	27260156	A673	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.5067417606914645	[906]	[985,633,703,769]	-8	hSpCas9	negative selection	5658106
139383335	139383358	3	+	27260156	A673	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.1127556196476225	[463]	[309,235,215,275]	-9	hSpCas9	negative selection	5658107
139375575	139375598	3	-	27260156	A673	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.46802485749282247	[812]	[705,698,662,756]	-8	hSpCas9	negative selection	5722376
139379404	139379427	3	-	27260156	A673	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.23908177768807554	[600]	[615,612,619,594]	-5	hSpCas9	negative selection	5722377
139375568	139375591	3	+	27260156	A673	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.5234679973475271	[295]	[294,199,241,258]	-8	hSpCas9	negative selection	5722378
139379411	139379434	3	+	27260156	A375	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.5296622230242356	[426]	[809,738,755,590]	7	hSpCas9	negative selection	5779356
139383375	139383398	3	-	27260156	A375	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.410787567413015	[906]	[564,363,310,353]	-9	hSpCas9	negative selection	5779357
139383335	139383358	3	+	27260156	A375	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-3.149310400068375	[463]	[67,69,51,55]	-9	hSpCas9	negative selection	5779358
139375575	139375598	3	-	27260156	A375	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.379591158176307	[812]	[326,489,399,269]	-9	hSpCas9	negative selection	5843627
139379404	139379427	3	-	27260156	A375	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.31388925575370275	[600]	[593,501,650,507]	-4	hSpCas9	negative selection	5843628
139375568	139375591	3	+	27260156	A375	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.1188235932308863	[295]	[176,149,120,183]	-8	hSpCas9	negative selection	5843629
139379411	139379434	3	+	27260156	COLO741	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.2924393354095276	[426]	[588,843,570]	6	hSpCas9	negative selection	5900607
139383375	139383398	3	-	27260156	COLO741	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.4788743411108197	[906]	[1134,845,557]	-7	hSpCas9	negative selection	5900608
139383335	139383358	3	+	27260156	COLO741	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.968066121011176	[463]	[161,125,165]	-9	hSpCas9	negative selection	5900609
139375575	139375598	3	-	27260156	COLO741	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.426049400701569	[812]	[613,992,702]	-7	hSpCas9	negative selection	5964878
139379404	139379427	3	-	27260156	COLO741	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.044937057868862096	[600]	[734,895,609]	-1	hSpCas9	negative selection	5964879
139375568	139375591	3	+	27260156	COLO741	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.6498052051444376	[295]	[222,324,177]	-8	hSpCas9	negative selection	5964880
139379411	139379434	3	+	27260156	CAL120	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.3336126751056002	[426]	[772,689,562]	5	hSpCas9	negative selection	6021858
139383375	139383398	3	-	27260156	CAL120	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.030889465427379	[906]	[550,402,699]	-8	hSpCas9	negative selection	6021859
139383335	139383358	3	+	27260156	CAL120	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-3.057306970762211	[463]	[25,131,43]	-9	hSpCas9	negative selection	6021860
139375575	139375598	3	-	27260156	CAL120	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.7566983451402816	[812]	[618,631,548]	-8	hSpCas9	negative selection	6086129
139379404	139379427	3	-	27260156	CAL120	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.3737423220216159	[600]	[1237,898,812]	5	hSpCas9	negative selection	6086130
139375568	139375591	3	+	27260156	CAL120	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.177788211300678	[295]	[435,322,235]	-3	hSpCas9	negative selection	6086131
139379411	139379434	3	+	27260156	CADOES1	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.3551558410935867	[426]	[478,464,602,483]	6	hSpCas9	negative selection	6143109
139383375	139383398	3	-	27260156	CADOES1	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.8216485355964351	[906]	[417,394,518,580]	-8	hSpCas9	negative selection	6143110
139383335	139383358	3	+	27260156	CADOES1	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.7990267247772282	[463]	[189,60,88,156]	-9	hSpCas9	negative selection	6143111
139375575	139375598	3	-	27260156	CADOES1	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.0253204745189608	[812]	[330,337,444,371]	-9	hSpCas9	negative selection	6207380
139379404	139379427	3	-	27260156	CADOES1	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.3715791056437756	[600]	[513,264,429,521]	-6	hSpCas9	negative selection	6207381
139375568	139375591	3	+	27260156	CADOES1	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.8152796461075331	[295]	[211,83,185,142]	-8	hSpCas9	negative selection	6207382
139379411	139379434	3	+	27260156	EWS502	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.183812386831879	[426]	[579,374,509,590]	3	hSpCas9	negative selection	6264360
139383375	139383398	3	-	27260156	EWS502	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.2122015539238096	[906]	[405,386,445,420]	-9	hSpCas9	negative selection	6264361
139383335	139383358	3	+	27260156	EWS502	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.5314683902692368	[463]	[52,49,109,135]	-9	hSpCas9	negative selection	6264362
139375575	139375598	3	-	27260156	EWS502	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.136954245217845	[812]	[462,363,360,366]	-9	hSpCas9	negative selection	6328631
139379404	139379427	3	-	27260156	EWS502	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.23623654704620495	[600]	[363,538,624,662]	-4	hSpCas9	negative selection	6328632
139375568	139375591	3	+	27260156	EWS502	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.1683590258461325	[295]	[156,132,147,115]	-9	hSpCas9	negative selection	6328633
139379411	139379434	3	+	27260156	EW8	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.5016835772381085	[426]	[906,385,265,482]	8	hSpCas9	negative selection	6385611
139383375	139383398	3	-	27260156	EW8	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.7253900943892428	[906]	[686,488,232,430]	-8	hSpCas9	negative selection	6385612
139383335	139383358	3	+	27260156	EW8	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.6970687846705734	[463]	[74,125,121,134]	-9	hSpCas9	negative selection	6385613
139375575	139375598	3	-	27260156	EW8	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.7184951839948518	[812]	[425,536,270,391]	-8	hSpCas9	negative selection	6449882
139379404	139379427	3	-	27260156	EW8	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.1751008054565019	[600]	[392,469,342,528]	-3	hSpCas9	negative selection	6449883
139375568	139375591	3	+	27260156	EW8	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.7305149571557794	[295]	[213,125,105,145]	-8	hSpCas9	negative selection	6449884
139379411	139379434	3	+	27260156	CORL105	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.11825181228614444	[426]	[504,608,625,440]	2	hSpCas9	negative selection	6506862
139383375	139383398	3	-	27260156	CORL105	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.8056261557642965	[906]	[428,582,849,599]	-8	hSpCas9	negative selection	6506863
139383335	139383358	3	+	27260156	CORL105	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-0.9652886759203725	[463]	[338,278,258,234]	-9	hSpCas9	negative selection	6506864
139375575	139375598	3	-	27260156	CORL105	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.8762038550075752	[812]	[433,577,563,500]	-9	hSpCas9	negative selection	6571133
139379404	139379427	3	-	27260156	CORL105	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.30382334735287597	[600]	[600,494,675,526]	-5	hSpCas9	negative selection	6571134
139375568	139375591	3	+	27260156	CORL105	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.1507536030993482	[295]	[172,154,162,134]	-9	hSpCas9	negative selection	6571135
139379411	139379434	3	+	27260156	HS294T	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.1070759978811604	[426]	[235,280,340,621]	9	hSpCas9	negative selection	6628113
139383375	139383398	3	-	27260156	HS294T	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.9361126509932318	[906]	[113,107,280,249]	-8	hSpCas9	negative selection	6628114
139383335	139383358	3	+	27260156	HS294T	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.8028688458783704	[463]	[24,41,76,66]	-9	hSpCas9	negative selection	6628115
139375575	139375598	3	-	27260156	HS294T	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.4052024777998975	[812]	[69,64,151,208]	-9	hSpCas9	negative selection	6692384
139379404	139379427	3	-	27260156	HS294T	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.17659502697480822	[600]	[171,255,225,161]	-2	hSpCas9	negative selection	6692385
139375568	139375591	3	+	27260156	HS294T	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.483903777612827	[295]	[30,21,61,51]	-9	hSpCas9	negative selection	6692386
139379411	139379434	3	+	27260156	HCC44	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.27320049515718076	[426]	[682,441,674,574]	4	hSpCas9	negative selection	6749364
139383375	139383398	3	-	27260156	HCC44	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.2050659282021234	[906]	[389,430,539,428]	-9	hSpCas9	negative selection	6749365
139383335	139383358	3	+	27260156	HCC44	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.949450113644248	[463]	[121,2,89,73]	-9	hSpCas9	negative selection	6749366
139375575	139375598	3	-	27260156	HCC44	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.4655303747574935	[812]	[259,277,246,523]	-9	hSpCas9	negative selection	6813635
139379404	139379427	3	-	27260156	HCC44	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.22831664339408358	[600]	[893,762,800,736]	3	hSpCas9	negative selection	6813636
139375568	139375591	3	+	27260156	HCC44	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.7658963357120439	[295]	[276,276,140,80]	-8	hSpCas9	negative selection	6813637
139379411	139379434	3	+	27260156	G402	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.7966560997915477	[426]	[962,801,607,1229]	8	hSpCas9	negative selection	6870615
139383375	139383398	3	-	27260156	G402	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.2682676116147844	[906]	[648,354,491,365]	-8	hSpCas9	negative selection	6870616
139383335	139383358	3	+	27260156	G402	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.500183616284125	[463]	[217,32,39,120]	-9	hSpCas9	negative selection	6870617
139375575	139375598	3	-	27260156	G402	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.9709428887870231	[812]	[892,422,452,313]	-8	hSpCas9	negative selection	6934886
139379404	139379427	3	-	27260156	G402	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.09841221837835962	[600]	[708,599,901,898]	1	hSpCas9	negative selection	6934887
139375568	139375591	3	+	27260156	G402	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.1203556828024255	[295]	[140,233,160,129]	-8	hSpCas9	negative selection	6934888
139379411	139379434	3	+	27260156	L33	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	-0.21748961761824137	[426]	[328,211,223,267]	-5	hSpCas9	negative selection	6991866
139383375	139383398	3	-	27260156	L33	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.04886528560235326	[906]	[825,356,548,936]	-1	hSpCas9	negative selection	6991867
139383335	139383358	3	+	27260156	L33	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-0.7698607255421723	[463]	[199,132,132,352]	-9	hSpCas9	negative selection	6991868
139375575	139375598	3	-	27260156	L33	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.24228424082960953	[812]	[731,247,477,650]	-5	hSpCas9	negative selection	7056137
139379404	139379427	3	-	27260156	L33	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.21454253311490268	[600]	[541,200,353,475]	-5	hSpCas9	negative selection	7056138
139375568	139375591	3	+	27260156	L33	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.21504477013835865	[295]	[189,118,142,312]	-5	hSpCas9	negative selection	7056139
139379411	139379434	3	+	27260156	K562	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.6946309843658814	[426]	[396,614,864,561]	8	hSpCas9	negative selection	7113117
139383375	139383398	3	-	27260156	K562	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.1921531415618147	[906]	[389,321,466,242]	-8	hSpCas9	negative selection	7113118
139383335	139383358	3	+	27260156	K562	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-4.302185547410149	[463]	[27,5,16,30]	-9	hSpCas9	negative selection	7113119
139375575	139375598	3	-	27260156	K562	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.548878177022627	[812]	[185,120,384,277]	-9	hSpCas9	negative selection	7177388
139379404	139379427	3	-	27260156	K562	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.11176570759169552	[600]	[571,391,622,691]	1	hSpCas9	negative selection	7177389
139375568	139375591	3	+	27260156	K562	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.5167738204360919	[295]	[171,150,290,123]	-6	hSpCas9	negative selection	7177390
139379411	139379434	3	+	27260156	HT29	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.4762852751120804	[426]	[789,626,846,627]	8	hSpCas9	negative selection	7234368
139383375	139383398	3	-	27260156	HT29	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.28662982000455	[906]	[439,518,538,326]	-9	hSpCas9	negative selection	7234369
139383335	139383358	3	+	27260156	HT29	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.8269324273637944	[463]	[64,66,74,104]	-9	hSpCas9	negative selection	7234370
139375575	139375598	3	-	27260156	HT29	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.7193421081872842	[812]	[366,305,257,275]	-9	hSpCas9	negative selection	7298639
139379404	139379427	3	-	27260156	HT29	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.1326940615971885	[600]	[682,825,664,519]	-3	hSpCas9	negative selection	7298640
139375568	139375591	3	+	27260156	HT29	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.8493852486355804	[295]	[249,247,184,130]	-8	hSpCas9	negative selection	7298641
139379411	139379434	3	+	27260156	MHHES1	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.2578459294260961	[426]	[832,461,680,377]	5	hSpCas9	negative selection	7355619
139383375	139383398	3	-	27260156	MHHES1	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.063598818312356	[906]	[687,688,339,311]	-9	hSpCas9	negative selection	7355620
139383335	139383358	3	+	27260156	MHHES1	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-0.9938490284593829	[463]	[281,255,314,205]	-9	hSpCas9	negative selection	7355621
139375575	139375598	3	-	27260156	MHHES1	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.869166046199165	[812]	[579,391,528,492]	-9	hSpCas9	negative selection	7419890
139379404	139379427	3	-	27260156	MHHES1	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.467335397103155	[600]	[359,491,695,404]	-7	hSpCas9	negative selection	7419891
139375568	139375591	3	+	27260156	MHHES1	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.8879165107003018	[295]	[141,200,281,106]	-9	hSpCas9	negative selection	7419892
139379411	139379434	3	+	27260156	MEWO	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.027846657733871974	[426]	[594,220,442]	0	hSpCas9	negative selection	7476870
139383375	139383398	3	-	27260156	MEWO	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.7541744567184705	[906]	[538,529,446]	-9	hSpCas9	negative selection	7476871
139383335	139383358	3	+	27260156	MEWO	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.713856787057306	[463]	[127,158,108]	-9	hSpCas9	negative selection	7476872
139375575	139375598	3	-	27260156	MEWO	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.6497346545713913	[812]	[486,433,533]	-8	hSpCas9	negative selection	7541141
139379404	139379427	3	-	27260156	MEWO	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.23798000421295462	[600]	[469,453,504]	-5	hSpCas9	negative selection	7541142
139375568	139375591	3	+	27260156	MEWO	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.32611486402944434	[295]	[279,240,152]	-6	hSpCas9	negative selection	7541143
139379411	139379434	3	+	27260156	LNCAPCLONEFGC	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.14884696352768698	[426]	[417,453,417,421]	2	hSpCas9	negative selection	7598121
139383375	139383398	3	-	27260156	LNCAPCLONEFGC	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.931915040273494	[906]	[430,339,569,407]	-8	hSpCas9	negative selection	7598122
139383335	139383358	3	+	27260156	LNCAPCLONEFGC	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.3223575665333764	[463]	[109,83,106,37]	-9	hSpCas9	negative selection	7598123
139375575	139375598	3	-	27260156	LNCAPCLONEFGC	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.9985233679408037	[812]	[339,304,368,464]	-8	hSpCas9	negative selection	7662392
139379404	139379427	3	-	27260156	LNCAPCLONEFGC	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.22247469174504603	[600]	[501,569,855,651]	3	hSpCas9	negative selection	7662393
139375568	139375591	3	+	27260156	LNCAPCLONEFGC	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.7256998889771569	[295]	[135,115,188,214]	-8	hSpCas9	negative selection	7662394
139379411	139379434	3	+	27260156	PANC0327	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.5976515193740034	[426]	[902,479,565,385]	8	hSpCas9	negative selection	7719372
139383375	139383398	3	-	27260156	PANC0327	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.029762584332236997	[906]	[840,435,1063,865]	0	hSpCas9	negative selection	7719373
139383335	139383358	3	+	27260156	PANC0327	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-3.9662377972428318	[463]	[20,26,46,9]	-9	hSpCas9	negative selection	7719374
139375575	139375598	3	-	27260156	PANC0327	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.4914858490447642	[812]	[194,234,256,337]	-9	hSpCas9	negative selection	7783643
139379404	139379427	3	-	27260156	PANC0327	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.05135234698550989	[600]	[563,619,541,478]	0	hSpCas9	negative selection	7783644
139375568	139375591	3	+	27260156	PANC0327	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.9274500341721958	[295]	[85,119,144,199]	-8	hSpCas9	negative selection	7783645
139379411	139379434	3	+	27260156	NCIH2009	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.17712697261937682	[426]	[647,848,516]	2	hSpCas9	negative selection	7840623
139383375	139383398	3	-	27260156	NCIH2009	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.3388314299330777	[906]	[676,439,420]	-8	hSpCas9	negative selection	7840624
139383335	139383358	3	+	27260156	NCIH2009	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-4.226119672578848	[463]	[64,26,17]	-9	hSpCas9	negative selection	7840625
139375575	139375598	3	-	27260156	NCIH2009	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-2.1182476041799863	[812]	[349,200,251]	-9	hSpCas9	negative selection	7904894
139379404	139379427	3	-	27260156	NCIH2009	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.3826523742744963	[600]	[911,371,704]	-5	hSpCas9	negative selection	7904895
139375568	139375591	3	+	27260156	NCIH2009	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.9011345864135001	[295]	[169,154,329]	-8	hSpCas9	negative selection	7904896
139379411	139379434	3	+	27260156	NCIH1373	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.08201929511630737	[426]	[588,365,651,114]	0	hSpCas9	negative selection	7961874
139383375	139383398	3	-	27260156	NCIH1373	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.8644804374079209	[906]	[700,621,440,125]	-7	hSpCas9	negative selection	7961875
139383335	139383358	3	+	27260156	NCIH1373	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.5866599778047212	[463]	[55,75,128,20]	-9	hSpCas9	negative selection	7961876
139375575	139375598	3	-	27260156	NCIH1373	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.8053985220942264	[812]	[480,159,338,24]	-9	hSpCas9	negative selection	8026145
139379404	139379427	3	-	27260156	NCIH1373	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.44640967979098406	[600]	[854,757,1198,223]	4	hSpCas9	negative selection	8026146
139375568	139375591	3	+	27260156	NCIH1373	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.7521637520947073	[295]	[306,82,241,47]	-6	hSpCas9	negative selection	8026147
139379411	139379434	3	+	27260156	PATU8902	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.45160863230247156	[426]	[738,452,1101,885]	5	hSpCas9	negative selection	8083125
139383375	139383398	3	-	27260156	PATU8902	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.4273560626682265	[906]	[714,474,106,695]	-8	hSpCas9	negative selection	8083126
139383335	139383358	3	+	27260156	PATU8902	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-4.758687241219806	[463]	[75,14,1,4]	-9	hSpCas9	negative selection	8083127
139375575	139375598	3	-	27260156	PATU8902	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-2.102573050444568	[812]	[225,240,137,509]	-9	hSpCas9	negative selection	8147396
139379404	139379427	3	-	27260156	PATU8902	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.451918305620556	[600]	[987,778,173,610]	-4	hSpCas9	negative selection	8147397
139375568	139375591	3	+	27260156	PATU8902	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-2.225626531110983	[295]	[9,115,110,112]	-9	hSpCas9	negative selection	8147398
139379411	139379434	3	+	27260156	PANC1	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.28122358261839064	[426]	[475,655,323,372]	4	hSpCas9	negative selection	8204376
139383375	139383398	3	-	27260156	PANC1	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.942099388250574	[906]	[349,418,620,255]	-8	hSpCas9	negative selection	8204377
139383335	139383358	3	+	27260156	PANC1	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-3.8537190768048823	[463]	[10,22,31,40]	-9	hSpCas9	negative selection	8204378
139375575	139375598	3	-	27260156	PANC1	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.6298994600696457	[812]	[345,149,171,213]	-9	hSpCas9	negative selection	8268647
139379404	139379427	3	-	27260156	PANC1	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.05547944374139474	[600]	[557,780,377,477]	0	hSpCas9	negative selection	8268648
139375568	139375591	3	+	27260156	PANC1	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.0133539410441572	[295]	[173,161,62,110]	-8	hSpCas9	negative selection	8268649
139379411	139379434	3	+	27260156	PANC0813	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.27099508650176396	[426]	[615,574,590,636]	4	hSpCas9	negative selection	8325627
139383375	139383398	3	-	27260156	PANC0813	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.0448581764987364	[906]	[481,559,426,587]	-8	hSpCas9	negative selection	8325628
139383335	139383358	3	+	27260156	PANC0813	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.183520057510569	[463]	[70,82,190,129]	-9	hSpCas9	negative selection	8325629
139375575	139375598	3	-	27260156	PANC0813	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.6496446503033595	[812]	[479,256,247,250]	-9	hSpCas9	negative selection	8389898
139379404	139379427	3	-	27260156	PANC0813	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.12354169211752203	[600]	[696,1059,676,640]	2	hSpCas9	negative selection	8389899
139375568	139375591	3	+	27260156	PANC0813	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.175820242717495	[295]	[218,226,94,83]	-9	hSpCas9	negative selection	8389900
139379411	139379434	3	+	27260156	RDES	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.19846489207487328	[426]	[404,549,446,921]	3	hSpCas9	negative selection	8446878
139383375	139383398	3	-	27260156	RDES	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.9351296780630838	[906]	[428,514,623,643]	-9	hSpCas9	negative selection	8446879
139383335	139383358	3	+	27260156	RDES	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.9353968734271256	[463]	[75,104,169,236]	-9	hSpCas9	negative selection	8446880
139375575	139375598	3	-	27260156	RDES	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.3934310656669406	[812]	[307,226,488,427]	-9	hSpCas9	negative selection	8511149
139379404	139379427	3	-	27260156	RDES	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.19155071172103832	[600]	[472,578,568,848]	-3	hSpCas9	negative selection	8511150
139375568	139375591	3	+	27260156	RDES	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.786767462835047	[295]	[101,201,312,190]	-8	hSpCas9	negative selection	8511151
139379411	139379434	3	+	27260156	PC3	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.13118143373577362	[426]	[293,397,524,714]	3	hSpCas9	negative selection	8568129
139383375	139383398	3	-	27260156	PC3	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.22156359608109943	[906]	[448,684,1521,816]	-5	hSpCas9	negative selection	8568130
139383335	139383358	3	+	27260156	PC3	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.142470341323614	[463]	[111,209,458,177]	-9	hSpCas9	negative selection	8568131
139375575	139375598	3	-	27260156	PC3	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.11313433557923669	[812]	[494,590,1444,783]	-3	hSpCas9	negative selection	8632400
139379404	139379427	3	-	27260156	PC3	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	0.061372593990572766	[600]	[332,558,1259,677]	1	hSpCas9	negative selection	8632401
139375568	139375591	3	+	27260156	PC3	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	0.09447659303246281	[295]	[142,379,356,449]	2	hSpCas9	negative selection	8632402
139379411	139379434	3	+	27260156	PATU8988T	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.31366741976661433	[426]	[410,589,318,760]	5	hSpCas9	negative selection	8689380
139383375	139383398	3	-	27260156	PATU8988T	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.6759613405732068	[906]	[669,507,362,660]	-8	hSpCas9	negative selection	8689381
139383335	139383358	3	+	27260156	PATU8988T	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-2.4062869689529602	[463]	[108,74,123,23]	-9	hSpCas9	negative selection	8689382
139375575	139375598	3	-	27260156	PATU8988T	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.8882011508746454	[812]	[327,520,370,492]	-8	hSpCas9	negative selection	8753651
139379404	139379427	3	-	27260156	PATU8988T	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.30759276004706293	[600]	[490,436,473,471]	-5	hSpCas9	negative selection	8753652
139375568	139375591	3	+	27260156	PATU8988T	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.6634972376383448	[295]	[150,234,186,151]	-8	hSpCas9	negative selection	8753653
139379411	139379434	3	+	27260156	T47D	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.2650512332966192	[426]	[764,535,550,543]	5	hSpCas9	negative selection	8810631
139383375	139383398	3	-	27260156	T47D	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.6320746623012841	[906]	[721,637,725,642]	-8	hSpCas9	negative selection	8810632
139383335	139383358	3	+	27260156	T47D	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.5875574513328303	[463]	[193,189,153,180]	-9	hSpCas9	negative selection	8810633
139375575	139375598	3	-	27260156	T47D	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.0334822669004675	[812]	[535,340,452,533]	-9	hSpCas9	negative selection	8874902
139379404	139379427	3	-	27260156	T47D	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.06260450429280556	[600]	[797,589,643,656]	-1	hSpCas9	negative selection	8874903
139375568	139375591	3	+	27260156	T47D	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.4494545616391763	[295]	[249,195,273,295]	-7	hSpCas9	negative selection	8874904
139379411	139379434	3	+	27260156	SU8686	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.24791641559642927	[426]	[435,501,512,575]	4	hSpCas9	negative selection	8931882
139383375	139383398	3	-	27260156	SU8686	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-1.0300056873103955	[906]	[429,286,499,587]	-8	hSpCas9	negative selection	8931883
139383335	139383358	3	+	27260156	SU8686	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-3.0759002461522775	[463]	[30,42,82,67]	-9	hSpCas9	negative selection	8931884
139375575	139375598	3	-	27260156	SU8686	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-1.51458679449915	[812]	[255,304,303,257]	-9	hSpCas9	negative selection	8996153
139379404	139379427	3	-	27260156	SU8686	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.36388906819414935	[600]	[454,427,467,510]	-6	hSpCas9	negative selection	8996154
139375568	139375591	3	+	27260156	SU8686	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.9000423268178133	[295]	[105,101,218,226]	-8	hSpCas9	negative selection	8996155
139379411	139379434	3	+	27260156	SKES1	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.21904115295780524	[426]	[691,439,527,354]	5	hSpCas9	negative selection	9053133
139383375	139383398	3	-	27260156	SKES1	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.5973436044152822	[906]	[610,703,501,585]	-8	hSpCas9	negative selection	9053134
139383335	139383358	3	+	27260156	SKES1	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.186014325155782	[463]	[214,190,163,237]	-9	hSpCas9	negative selection	9053135
139375575	139375598	3	-	27260156	SKES1	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.5775099753473096	[812]	[707,620,464,421]	-8	hSpCas9	negative selection	9117404
139379404	139379427	3	-	27260156	SKES1	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.2895415504471451	[600]	[479,582,512,400]	-6	hSpCas9	negative selection	9117405
139375568	139375591	3	+	27260156	SKES1	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-1.0859288426133682	[295]	[155,115,138,142]	-9	hSpCas9	negative selection	9117406
139379411	139379434	3	+	27260156	TOV112D	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.24539052723834243	[426]	[600,775,357,369]	5	hSpCas9	negative selection	9174384
139383375	139383398	3	-	27260156	TOV112D	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.545320700398183	[906]	[544,964,555,503]	-8	hSpCas9	negative selection	9174385
139383335	139383358	3	+	27260156	TOV112D	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.2486416787922905	[463]	[185,287,209,121]	-9	hSpCas9	negative selection	9174386
139375575	139375598	3	-	27260156	TOV112D	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.42316944719986205	[812]	[612,963,392,547]	-7	hSpCas9	negative selection	9238655
139379404	139379427	3	-	27260156	TOV112D	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.04697999791180901	[600]	[550,649,721,424]	-1	hSpCas9	negative selection	9238656
139375568	139375591	3	+	27260156	TOV112D	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.5656531806810954	[295]	[132,303,156,225]	-8	hSpCas9	negative selection	9238657
139379411	139379434	3	+	27260156	TC71	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.21147735109571258	[426]	[638,423,480,577]	5	hSpCas9	negative selection	9295635
139383375	139383398	3	-	27260156	TC71	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.3086712855932736	[906]	[789,692,828,828]	-7	hSpCas9	negative selection	9295636
139383335	139383358	3	+	27260156	TC71	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-0.8409272646102707	[463]	[243,257,217,400]	-9	hSpCas9	negative selection	9295637
139375575	139375598	3	-	27260156	TC71	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.31666296413676925	[812]	[789,754,641,605]	-7	hSpCas9	negative selection	9359906
139379404	139379427	3	-	27260156	TC71	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.21792927669081952	[600]	[569,526,582,532]	-5	hSpCas9	negative selection	9359907
139375568	139375591	3	+	27260156	TC71	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.24006330933082243	[295]	[262,227,325,254]	-6	hSpCas9	negative selection	9359908
139379411	139379434	3	+	27260156	TC32	viability	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.7347294120918776	[426]	[670,562,652,784]	9	hSpCas9	negative selection	9416886
139383375	139383398	3	-	27260156	TC32	viability	ATCTGATCGAGTTAAGAGTGTGG	COPB2	ENSG00000184432	-0.5460183924671349	[906]	[527,376,782,742]	-8	hSpCas9	negative selection	9416887
139383335	139383358	3	+	27260156	TC32	viability	TAAAGACTTGCCAACATCCATGG	COPB2	ENSG00000184432	-1.020905191258656	[463]	[241,130,234,273]	-9	hSpCas9	negative selection	9416888
139375575	139375598	3	-	27260156	TC32	viability	TTCGTCACCAAACTTCACTTTGG	COPB2	ENSG00000184432	-0.5371269517651114	[812]	[408,479,647,593]	-8	hSpCas9	negative selection	9481157
139379404	139379427	3	-	27260156	TC32	viability	GAGCTGCAAAGTTTGTTGCAAGG	COPB2	ENSG00000184432	-0.37101276911198444	[600]	[313,358,745,398]	-6	hSpCas9	negative selection	9481158
139375568	139375591	3	+	27260156	TC32	viability	TGTCCTTCCAAAGTGAAGTTTGG	COPB2	ENSG00000184432	-0.4900055481180221	[295]	[153,219,200,201]	-7	hSpCas9	negative selection	9481159
139366648	139366671	3	-	27869803	HPAFII	viability after 27 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-3.4450463367243214	[257]	[0,21,NaN]	-9	hSpCas9	negative selection	9582835
139369355	139369378	3	-	27869803	HPAFII	viability after 27 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-6.720512728285493	[309]	[0,1,NaN]	-9	hSpCas9	negative selection	9582836
139373261	139373284	3	+	27869803	HPAFII	viability after 27 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-4.326660833000084	[228]	[11,0,NaN]	-9	hSpCas9	negative selection	9582837
139373714	139373737	3	-	27869803	HPAFII	viability after 27 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-0.8706050782775889	[220]	[2,113,NaN]	-6	hSpCas9	negative selection	9582838
139378041	139378064	3	+	27869803	HPAFII	viability after 27 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-2.7313571562536243	[541]	[85,6,NaN]	-9	hSpCas9	negative selection	9582839
139379411	139379434	3	+	27869803	HPAFII	viability after 27 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	2.179534699265288	[302]	[977,507,NaN]	9	hSpCas9	negative selection	9582840
139366648	139366671	3	-	27869803	HPAFII	viability after 15 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-2.6427367312412873	[257]	[36,48,NaN]	-9	hSpCas9	negative selection	9665284
139369355	139369378	3	-	27869803	HPAFII	viability after 15 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-3.922986143452578	[309]	[0,34,NaN]	-9	hSpCas9	negative selection	9665285
139373261	139373284	3	+	27869803	HPAFII	viability after 15 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-3.626101093078131	[228]	[14,22,NaN]	-9	hSpCas9	negative selection	9665286
139373714	139373737	3	-	27869803	HPAFII	viability after 15 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.108641409285255	[220]	[37,154,NaN]	-8	hSpCas9	negative selection	9665287
139378041	139378064	3	+	27869803	HPAFII	viability after 15 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-4.099185359271417	[541]	[78,5,NaN]	-9	hSpCas9	negative selection	9665288
139379411	139379434	3	+	27869803	HPAFII	viability after 15 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	1.2170315267739054	[302]	[1097,544,NaN]	9	hSpCas9	negative selection	9665289
139366648	139366671	3	-	27869803	ASPC1	viability after 36 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-4.658960501362098	[509]	[10,0,8]	-9	hSpCas9	negative selection	9747733
139369355	139369378	3	-	27869803	ASPC1	viability after 36 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-5.1515986658366835	[664]	[0,11,5]	-9	hSpCas9	negative selection	9747734
139373261	139373284	3	+	27869803	ASPC1	viability after 36 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-0.8853142706606641	[982]	[160,185,200]	-7	hSpCas9	negative selection	9747735
139373714	139373737	3	-	27869803	ASPC1	viability after 36 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-0.8368780404496076	[645]	[51,124,177]	-7	hSpCas9	negative selection	9747736
139378041	139378064	3	+	27869803	ASPC1	viability after 36 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.745610017034217	[1440]	[57,16,38]	-9	hSpCas9	negative selection	9747737
139379411	139379434	3	+	27869803	ASPC1	viability after 36 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.4595782909563769	[1229]	[806,877,203]	4	hSpCas9	negative selection	9747738
139366648	139366671	3	-	27869803	PATU8988S	viability after 35 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-1.7348258477675864	[429]	[65,37,NaN]	-8	hSpCas9	negative selection	9830182
139369355	139369378	3	-	27869803	PATU8988S	viability after 35 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-7.3450736819264435	[605]	[1,0,NaN]	-9	hSpCas9	negative selection	9830183
139373261	139373284	3	+	27869803	PATU8988S	viability after 35 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-3.6411170700946225	[728]	[37,8,NaN]	-9	hSpCas9	negative selection	9830184
139373714	139373737	3	-	27869803	PATU8988S	viability after 35 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.7888417622194452	[467]	[75,32,NaN]	-8	hSpCas9	negative selection	9830185
139378041	139378064	3	+	27869803	PATU8988S	viability after 35 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-4.065797461900962	[1288]	[30,30,NaN]	-9	hSpCas9	negative selection	9830186
139379411	139379434	3	+	27869803	PATU8988S	viability after 35 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.28404987896836165	[1091]	[538,531,NaN]	3	hSpCas9	negative selection	9830187
139366648	139366671	3	-	27869803	PATU8988S	viability after 31 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-3.287497266422383	[429]	[17,16,NaN]	-9	hSpCas9	negative selection	9912631
139369355	139369378	3	-	27869803	PATU8988S	viability after 31 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-4.7724531981828315	[605]	[14,0,NaN]	-9	hSpCas9	negative selection	9912632
139373261	139373284	3	+	27869803	PATU8988S	viability after 31 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-2.893383035323991	[728]	[50,23,NaN]	-9	hSpCas9	negative selection	9912633
139373714	139373737	3	-	27869803	PATU8988S	viability after 31 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-2.3965945217024442	[467]	[34,35,NaN]	-9	hSpCas9	negative selection	9912634
139378041	139378064	3	+	27869803	PATU8988S	viability after 31 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.426685396611645	[1288]	[38,58,NaN]	-9	hSpCas9	negative selection	9912635
139379411	139379434	3	+	27869803	PATU8988S	viability after 31 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	0.20409967526090145	[1091]	[494,509,NaN]	2	hSpCas9	negative selection	9912636
139366648	139366671	3	-	27869803	HPAFII	viability after 35 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-5.72441989757144	[257]	[1,2,NaN]	-9	hSpCas9	negative selection	9995080
139369355	139369378	3	-	27869803	HPAFII	viability after 35 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-7.294035852277563	[309]	[0,0,NaN]	-9	hSpCas9	negative selection	9995081
139373261	139373284	3	+	27869803	HPAFII	viability after 35 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-6.857115235100269	[228]	[0,0,NaN]	-9	hSpCas9	negative selection	9995082
139373714	139373737	3	-	27869803	HPAFII	viability after 35 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-0.6833082432404366	[220]	[0,146,NaN]	-4	hSpCas9	negative selection	9995083
139378041	139378064	3	+	27869803	HPAFII	viability after 35 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.1048798885833384	[541]	[53,6,NaN]	-8	hSpCas9	negative selection	9995084
139379411	139379434	3	+	27869803	HPAFII	viability after 35 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	2.575014834895175	[302]	[1215,573,NaN]	9	hSpCas9	negative selection	9995085
139366648	139366671	3	-	27869803	HPAFII	viability after 31 days	CCAGACAGCTGTCATGCGGAGGG	COPB2	ENSG00000184432	-7.177856055747997	[257]	[0,0,NaN]	-9	hSpCas9	negative selection	10077529
139369355	139369378	3	-	27869803	HPAFII	viability after 31 days	TTCCCTTTAGGTATCTACGGCGG	COPB2	ENSG00000184432	-6.47400413958342	[309]	[0,2,NaN]	-9	hSpCas9	negative selection	10077530
139373261	139373284	3	+	27869803	HPAFII	viability after 31 days	CCCATATCCTTTACTGCCAGTGG	COPB2	ENSG00000184432	-7.005832588421686	[228]	[0,0,NaN]	-9	hSpCas9	negative selection	10077531
139373714	139373737	3	-	27869803	HPAFII	viability after 31 days	GGTGCGTGGCCAGTCTAAGAGGG	COPB2	ENSG00000184432	-1.2046140587137477	[220]	[4,106,NaN]	-6	hSpCas9	negative selection	10077532
139378041	139378064	3	+	27869803	HPAFII	viability after 31 days	CTTGATAGTCCTGTCCAAAGAGG	COPB2	ENSG00000184432	-3.346704262367871	[541]	[49,7,NaN]	-9	hSpCas9	negative selection	10077533
139379411	139379434	3	+	27869803	HPAFII	viability after 31 days	ACAAACTTTGCAGCTCGAACAGG	COPB2	ENSG00000184432	2.3217223317989504	[302]	[1064,615,NaN]	9	hSpCas9	negative selection	10077534
139373316	139373339	3	-	28162770	P31FUJ	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.439253081881805	[119]	[51]	-7	hSpCas9	negative selection	10136715
139373746	139373769	3	-	28162770	P31FUJ	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-4.530482753055064	[117]	[5]	-9	hSpCas9	negative selection	10136716
139362406	139362429	3	-	28162770	P31FUJ	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	0.06464979847677702	[213]	[262]	0	hSpCas9	negative selection	10136717
139361208	139361231	3	-	28162770	P31FUJ	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-0.5846458772060285	[267]	[209]	-5	hSpCas9	negative selection	10136718
139361123	139361146	3	-	28162770	P31FUJ	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-5.139692800022897	[29]	[0]	-9	hSpCas9	negative selection	10136719
139379379	139379402	3	-	28162770	P31FUJ	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-2.0907831995419506	[28]	[7]	-8	hSpCas9	negative selection	10136720
139368179	139368202	3	-	28162770	P31FUJ	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	0.06976056560605248	[59]	[73]	0	hSpCas9	negative selection	10136721
139367011	139367034	3	+	28162770	P31FUJ	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-0.960889647234132	[269]	[162]	-6	hSpCas9	negative selection	10136722
139366598	139366621	3	-	28162770	P31FUJ	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.1510081132507315	[239]	[126]	-7	hSpCas9	negative selection	10136723
139361138	139361161	3	-	28162770	P31FUJ	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-0.1988548724910406	[41]	[42]	-2	hSpCas9	negative selection	10136724
139373316	139373339	3	-	28162770	TF1	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10306081
139373746	139373769	3	-	28162770	TF1	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10306082
139362406	139362429	3	-	28162770	TF1	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10306083
139361208	139361231	3	-	28162770	TF1	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10306084
139361123	139361146	3	-	28162770	TF1	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10306085
139379379	139379402	3	-	28162770	TF1	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10306086
139368179	139368202	3	-	28162770	TF1	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10306087
139367011	139367034	3	+	28162770	TF1	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10306088
139366598	139366621	3	-	28162770	TF1	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10306089
139361138	139361161	3	-	28162770	TF1	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10306090
139373316	139373339	3	-	28162770	SKM1	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-6.2143191208007655	[41]	[0]	-9	hSpCas9	negative selection	10475447
139373746	139373769	3	-	28162770	SKM1	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-3.3455636540790183	[45]	[7]	-9	hSpCas9	negative selection	10475448
139362406	139362429	3	-	28162770	SKM1	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-0.5282704949652954	[61]	[75]	-4	hSpCas9	negative selection	10475449
139361208	139361231	3	-	28162770	SKM1	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-3.0533272441284613	[107]	[22]	-9	hSpCas9	negative selection	10475450
139361123	139361146	3	-	28162770	SKM1	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-0.8220016980220057	[6]	[6]	-6	hSpCas9	negative selection	10475451
139379379	139379402	3	-	28162770	SKM1	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-4.281433316659303	[10]	[0]	-9	hSpCas9	negative selection	10475452
139368179	139368202	3	-	28162770	SKM1	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	0.37064337992039054	[6]	[15]	3	hSpCas9	negative selection	10475453
139367011	139367034	3	+	28162770	SKM1	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-4.237039197300849	[63]	[5]	-9	hSpCas9	negative selection	10475454
139366598	139366621	3	-	28162770	SKM1	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.5489832036155895	[47]	[28]	-8	hSpCas9	negative selection	10475455
139361138	139361161	3	-	28162770	SKM1	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-1.6293566200796095	[6]	[3]	-8	hSpCas9	negative selection	10475456
139373316	139373339	3	-	28162770	SKM1	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-6.2143191208007655	[41]	[0]	-9	hSpCas9	negative selection	10644813
139373746	139373769	3	-	28162770	SKM1	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-3.3455636540790183	[45]	[7]	-9	hSpCas9	negative selection	10644814
139362406	139362429	3	-	28162770	SKM1	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-0.5282704949652954	[61]	[75]	-4	hSpCas9	negative selection	10644815
139361208	139361231	3	-	28162770	SKM1	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-3.0533272441284613	[107]	[22]	-9	hSpCas9	negative selection	10644816
139361123	139361146	3	-	28162770	SKM1	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-0.8220016980220057	[6]	[6]	-6	hSpCas9	negative selection	10644817
139379379	139379402	3	-	28162770	SKM1	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-4.281433316659303	[10]	[0]	-9	hSpCas9	negative selection	10644818
139368179	139368202	3	-	28162770	SKM1	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	0.37064337992039054	[6]	[15]	3	hSpCas9	negative selection	10644819
139367011	139367034	3	+	28162770	SKM1	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-4.237039197300849	[63]	[5]	-9	hSpCas9	negative selection	10644820
139366598	139366621	3	-	28162770	SKM1	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.5489832036155895	[47]	[28]	-8	hSpCas9	negative selection	10644821
139361138	139361161	3	-	28162770	SKM1	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-1.6293566200796095	[6]	[3]	-8	hSpCas9	negative selection	10644822
139373316	139373339	3	-	28162770	PL21	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.6174836430221113	[140]	[19]	-8	hSpCas9	negative selection	10814179
139373746	139373769	3	-	28162770	PL21	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-2.362796579901837	[129]	[10]	-8	hSpCas9	negative selection	10814180
139362406	139362429	3	-	28162770	PL21	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	0.15707089259743423	[203]	[98]	1	hSpCas9	negative selection	10814181
139361208	139361231	3	-	28162770	PL21	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-2.15349734012538	[275]	[26]	-8	hSpCas9	negative selection	10814182
139361123	139361146	3	-	28162770	PL21	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-4.192177808289441	[41]	[0]	-9	hSpCas9	negative selection	10814183
139379379	139379402	3	-	28162770	PL21	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-4.00931375113963	[36]	[0]	-9	hSpCas9	negative selection	10814184
139368179	139368202	3	-	28162770	PL21	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-4.754056695897555	[61]	[0]	-9	hSpCas9	negative selection	10814185
139367011	139367034	3	+	28162770	PL21	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-1.3981197088452941	[217]	[35]	-7	hSpCas9	negative selection	10814186
139366598	139366621	3	-	28162770	PL21	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-3.1127433407950353	[158]	[7]	-9	hSpCas9	negative selection	10814187
139361138	139361161	3	-	28162770	PL21	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-2.323422341567693	[22]	[1]	-8	hSpCas9	negative selection	10814188
139373316	139373339	3	-	28162770	P31FUJ	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.439253081881805	[119]	[51]	-7	hSpCas9	negative selection	10983545
139373746	139373769	3	-	28162770	P31FUJ	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-4.530482753055064	[117]	[5]	-9	hSpCas9	negative selection	10983546
139362406	139362429	3	-	28162770	P31FUJ	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	0.06464979847677702	[213]	[262]	0	hSpCas9	negative selection	10983547
139361208	139361231	3	-	28162770	P31FUJ	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-0.5846458772060285	[267]	[209]	-5	hSpCas9	negative selection	10983548
139361123	139361146	3	-	28162770	P31FUJ	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-5.139692800022897	[29]	[0]	-9	hSpCas9	negative selection	10983549
139379379	139379402	3	-	28162770	P31FUJ	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-2.0907831995419506	[28]	[7]	-8	hSpCas9	negative selection	10983550
139368179	139368202	3	-	28162770	P31FUJ	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	0.06976056560605248	[59]	[73]	0	hSpCas9	negative selection	10983551
139367011	139367034	3	+	28162770	P31FUJ	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-0.960889647234132	[269]	[162]	-6	hSpCas9	negative selection	10983552
139366598	139366621	3	-	28162770	P31FUJ	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.1510081132507315	[239]	[126]	-7	hSpCas9	negative selection	10983553
139361138	139361161	3	-	28162770	P31FUJ	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-0.1988548724910406	[41]	[42]	-2	hSpCas9	negative selection	10983554
139373316	139373339	3	-	28162770	OCIAML5	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.691601898670751	[101]	[56]	-7	hSpCas9	negative selection	11152911
139373746	139373769	3	-	28162770	OCIAML5	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-1.343602207616884	[141]	[100]	-7	hSpCas9	negative selection	11152912
139362406	139362429	3	-	28162770	OCIAML5	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-1.403606070047703	[191]	[130]	-7	hSpCas9	negative selection	11152913
139361208	139361231	3	-	28162770	OCIAML5	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.4904683305466135	[164]	[105]	-7	hSpCas9	negative selection	11152914
139361123	139361146	3	-	28162770	OCIAML5	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-3.852066570863997	[7]	[0]	-9	hSpCas9	negative selection	11152915
139379379	139379402	3	-	28162770	OCIAML5	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-2.8520665708639967	[3]	[0]	-8	hSpCas9	negative selection	11152916
139368179	139368202	3	-	28162770	OCIAML5	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-0.9639594509348944	[66]	[61]	-6	hSpCas9	negative selection	11152917
139367011	139367034	3	+	28162770	OCIAML5	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-2.574532595335088	[164]	[49]	-8	hSpCas9	negative selection	11152918
139366598	139366621	3	-	28162770	OCIAML5	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.6368984762954617	[142]	[82]	-7	hSpCas9	negative selection	11152919
139361138	139361161	3	-	28162770	OCIAML5	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-1.224035348250955	[21]	[16]	-6	hSpCas9	negative selection	11152920
139373316	139373339	3	-	28162770	EOL1	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-2.9301128652654262	[216]	[14]	-9	hSpCas9	negative selection	11322277
139373746	139373769	3	-	28162770	EOL1	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-3.2184101822715085	[158]	[8]	-9	hSpCas9	negative selection	11322278
139362406	139362429	3	-	28162770	EOL1	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	0.5638759754082395	[433]	[337]	5	hSpCas9	negative selection	11322279
139361208	139361231	3	-	28162770	EOL1	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.0030437329014155	[543]	[142]	-6	hSpCas9	negative selection	11322280
139361123	139361146	3	-	28162770	EOL1	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-5.204735245374431	[69]	[0]	-9	hSpCas9	negative selection	11322281
139379379	139379402	3	-	28162770	EOL1	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-2.179788888244201	[42]	[4]	-8	hSpCas9	negative selection	11322282
139368179	139368202	3	-	28162770	EOL1	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-2.0573048817192063	[78]	[9]	-8	hSpCas9	negative selection	11322283
139367011	139367034	3	+	28162770	EOL1	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-1.3762415562586774	[270]	[54]	-7	hSpCas9	negative selection	11322284
139366598	139366621	3	-	28162770	EOL1	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-2.348470722835881	[202]	[20]	-8	hSpCas9	negative selection	11322285
139361138	139361161	3	-	28162770	EOL1	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-1.8033726829926646	[52]	[7]	-8	hSpCas9	negative selection	11322286
139373316	139373339	3	-	28162770	MOLM13	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-7.239469750536304	[208]	[0]	-9	hSpCas9	negative selection	11491643
139373746	139373769	3	-	28162770	MOLM13	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-3.3117205500301212	[205]	[14]	-8	hSpCas9	negative selection	11491644
139362406	139362429	3	-	28162770	MOLM13	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-1.011890882484521	[356]	[127]	-5	hSpCas9	negative selection	11491645
139361208	139361231	3	-	28162770	MOLM13	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.6179084912106505	[432]	[101]	-7	hSpCas9	negative selection	11491646
139361123	139361146	3	-	28162770	MOLM13	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-4.1170731191765775	[47]	[1]	-9	hSpCas9	negative selection	11491647
139379379	139379402	3	-	28162770	MOLM13	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-4.532110618455421	[31]	[0]	-9	hSpCas9	negative selection	11491648
139368179	139368202	3	-	28162770	MOLM13	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-4.232550336596514	[103]	[3]	-9	hSpCas9	negative selection	11491649
139367011	139367034	3	+	28162770	MOLM13	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-7.987437838759982	[350]	[0]	-9	hSpCas9	negative selection	11491650
139366598	139366621	3	-	28162770	MOLM13	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-5.9140860970127225	[416]	[4]	-9	hSpCas9	negative selection	11491651
139361138	139361161	3	-	28162770	MOLM13	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-5.339465540513025	[55]	[0]	-9	hSpCas9	negative selection	11491652
139373316	139373339	3	-	28162770	HEL	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-2.0324214776923775	[197]	[30]	-8	hSpCas9	negative selection	11661009
139373746	139373769	3	-	28162770	HEL	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-4.3840612273433575	[162]	[4]	-9	hSpCas9	negative selection	11661010
139362406	139362429	3	-	28162770	HEL	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-0.04993748602105255	[277]	[171]	0	hSpCas9	negative selection	11661011
139361208	139361231	3	-	28162770	HEL	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	0.61950652576264	[312]	[307]	5	hSpCas9	negative selection	11661012
139361123	139361146	3	-	28162770	HEL	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-4.880823124056656	[45]	[0]	-9	hSpCas9	negative selection	11661013
139379379	139379402	3	-	28162770	HEL	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-3.749578590778403	[20]	[0]	-9	hSpCas9	negative selection	11661014
139368179	139368202	3	-	28162770	HEL	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-1.7108981226143434	[91]	[17]	-7	hSpCas9	negative selection	11661015
139367011	139367034	3	+	28162770	HEL	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-4.561133501365293	[257]	[6]	-9	hSpCas9	negative selection	11661016
139366598	139366621	3	-	28162770	HEL	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-2.8403440547015855	[245]	[21]	-8	hSpCas9	negative selection	11661017
139361138	139361161	3	-	28162770	HEL	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-1.3967895321862804	[36]	[8]	-7	hSpCas9	negative selection	11661018
139373316	139373339	3	-	28162770	MV411	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-3.415527461939654	[151]	[11]	-9	hSpCas9	negative selection	11830375
139373746	139373769	3	-	28162770	MV411	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-2.0606847445795564	[103]	[20]	-8	hSpCas9	negative selection	11830376
139362406	139362429	3	-	28162770	MV411	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-0.9088383891476859	[262]	[117]	-6	hSpCas9	negative selection	11830377
139361208	139361231	3	-	28162770	MV411	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.031898667380119	[266]	[109]	-6	hSpCas9	negative selection	11830378
139361123	139361146	3	-	28162770	MV411	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-5.307151300894862	[46]	[0]	-9	hSpCas9	negative selection	11830379
139379379	139379402	3	-	28162770	MV411	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-3.337524949938381	[11]	[0]	-9	hSpCas9	negative selection	11830380
139368179	139368202	3	-	28162770	MV411	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-0.04534419844507087	[48]	[39]	0	hSpCas9	negative selection	11830381
139367011	139367034	3	+	28162770	MV411	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-3.262117547280358	[204]	[17]	-9	hSpCas9	negative selection	11830382
139366598	139366621	3	-	28162770	MV411	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.7415913313962217	[130]	[32]	-8	hSpCas9	negative selection	11830383
139361138	139361161	3	-	28162770	MV411	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-2.922487450659537	[26]	[2]	-9	hSpCas9	negative selection	11830384
139373316	139373339	3	-	28162770	MONOMAC1	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-2.924957301622753	[105]	[15]	-9	hSpCas9	negative selection	11999741
139373746	139373769	3	-	28162770	MONOMAC1	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-1.4449643605031395	[75]	[31]	-8	hSpCas9	negative selection	11999742
139362406	139362429	3	-	28162770	MONOMAC1	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-1.2814290343499262	[175]	[82]	-7	hSpCas9	negative selection	11999743
139361208	139361231	3	-	28162770	MONOMAC1	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.2715838004246076	[138]	[65]	-7	hSpCas9	negative selection	11999744
139361123	139361146	3	-	28162770	MONOMAC1	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-3.78199934778071	[11]	[0]	-9	hSpCas9	negative selection	11999745
139379379	139379402	3	-	28162770	MONOMAC1	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-4.444964360503139	[18]	[0]	-9	hSpCas9	negative selection	11999746
139368179	139368202	3	-	28162770	MONOMAC1	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-4.366961848501866	[35]	[1]	-9	hSpCas9	negative selection	11999747
139367011	139367034	3	+	28162770	MONOMAC1	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-4.0043917691171576	[125]	[8]	-9	hSpCas9	negative selection	11999748
139366598	139366621	3	-	28162770	MONOMAC1	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-2.2345115524782164	[77]	[18]	-9	hSpCas9	negative selection	11999749
139361138	139361161	3	-	28162770	MONOMAC1	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-4.518964941946916	[19]	[0]	-9	hSpCas9	negative selection	11999750
139373316	139373339	3	-	28162770	OCIAML2	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-1.4706298252421615	[24]	[49]	-7	hSpCas9	negative selection	12169107
139373746	139373769	3	-	28162770	OCIAML2	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-3.409229280578018	[22]	[11]	-9	hSpCas9	negative selection	12169108
139362406	139362429	3	-	28162770	OCIAML2	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-1.3710941516912465	[41]	[89]	-7	hSpCas9	negative selection	12169109
139361208	139361231	3	-	28162770	OCIAML2	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-0.49919897743893216	[50]	[199]	-4	hSpCas9	negative selection	12169110
139361123	139361146	3	-	28162770	OCIAML2	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-5.0555923259633175	[5]	[0]	-9	hSpCas9	negative selection	12169111
139379379	139379402	3	-	28162770	OCIAML2	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-2.4706298252421615	[3]	[3]	-8	hSpCas9	negative selection	12169112
139368179	139368202	3	-	28162770	OCIAML2	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	-1.5961607073260202	[5]	[10]	-7	hSpCas9	negative selection	12169113
139367011	139367034	3	+	28162770	OCIAML2	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-2.73981645805755	[46]	[38]	-9	hSpCas9	negative selection	12169114
139366598	139366621	3	-	28162770	OCIAML2	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.1227065218218544	[21]	[55]	-6	hSpCas9	negative selection	12169115
139361138	139361161	3	-	28162770	OCIAML2	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	-1.733664231075955	[8]	[14]	-8	hSpCas9	negative selection	12169116
139373316	139373339	3	-	28162770	OCIAML3	viability	GCAGGCCAACCTAAAAGCAATGG	COPB2	ENSG00000184432	-2.3440293873158153	[36]	[21]	-9	hSpCas9	negative selection	12338473
139373746	139373769	3	-	28162770	OCIAML3	viability	GAGCACACTGAATTATGGAATGG	COPB2	ENSG00000184432	-6.117569596381176	[45]	[1]	-9	hSpCas9	negative selection	12338474
139362406	139362429	3	-	28162770	OCIAML3	viability	CCAGTTAGCAGTGGAAGCAGAGG	COPB2	ENSG00000184432	-1.5180587870908646	[73]	[77]	-8	hSpCas9	negative selection	12338475
139361208	139361231	3	-	28162770	OCIAML3	viability	GGAGTGCCTGCATCATGCACAGG	COPB2	ENSG00000184432	-1.3916994650310477	[92]	[106]	-7	hSpCas9	negative selection	12338476
139361123	139361146	3	-	28162770	OCIAML3	viability	GCAGAGGGTGCGGAGAGAGATGG	COPB2	ENSG00000184432	-4.763932641766475	[8]	[0]	-9	hSpCas9	negative selection	12338477
139379379	139379402	3	-	28162770	OCIAML3	viability	GAATTGGGTTGTGACAGGAGCGG	COPB2	ENSG00000184432	-4.178970141045319	[5]	[0]	-9	hSpCas9	negative selection	12338478
139368179	139368202	3	-	28162770	OCIAML3	viability	GCTGCACAGGAAACACATGAGGG	COPB2	ENSG00000184432	0.8389517669519428	[9]	[53]	7	hSpCas9	negative selection	12338479
139367011	139367034	3	+	28162770	OCIAML3	viability	GTACCTGTCCAAGTGGGCAATGG	COPB2	ENSG00000184432	-2.62148837674627	[52]	[25]	-9	hSpCas9	negative selection	12338480
139366598	139366621	3	-	28162770	OCIAML3	viability	CTACCATTCCAAAAGAACAGAGG	COPB2	ENSG00000184432	-1.0321287527160483	[41]	[61]	-6	hSpCas9	negative selection	12338481
139361138	139361161	3	-	28162770	OCIAML3	viability	ATGGTGAACAAGCTAGCAGAGGG	COPB2	ENSG00000184432	0.6744811956017387	[10]	[52]	6	hSpCas9	negative selection	12338482