| 82635183 | 82635206 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | GCAGAGGTGGAGAAATGCGAAGG | CPEB1 | ENSG00000277445 | 0.19772201587692373 | [36] | [31] | 1 | hSpCas9 | negative selection | 36250 | 82628699 | 82628722 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | GCTCCGGACAAAGTTACTGTCGG | CPEB1 | ENSG00000277445 | 0.4643192886094823 | [98] | [102] | 3 | hSpCas9 | negative selection | 36251 | 82650548 | 82650571 | CHR_HSCHR15_5_CTG8 | - | 26472758 | Jiyoye | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000277445 | 0.38065450525318045 | [548] | [538] | 3 | hSpCas9 | negative selection | 36252 | 82571460 | 82571483 | 15 | - | 26472758 | Jiyoye | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.38065450525318045 | [548] | [538] | 3 | hSpCas9 | negative selection | 36253 | 82635167 | 82635190 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | GACAGAGACAGGAAGGGCAGAGG | CPEB1 | ENSG00000277445 | -2.0804899178603677 | [128] | [22] | -8 | hSpCas9 | negative selection | 36254 | 82633019 | 82633042 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | GGGTTCTTATAGTTCCGGGGAGG | CPEB1 | ENSG00000277445 | -0.7854696964365224 | [223] | [97] | -5 | hSpCas9 | negative selection | 36255 | 82650501 | 82650524 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000277445 | 1.3024780028391802 | [99] | [185] | 7 | hSpCas9 | negative selection | 36256 | 82571413 | 82571436 | 15 | + | 26472758 | Jiyoye | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.3024780028391802 | [99] | [185] | 7 | hSpCas9 | negative selection | 36257 | 82636990 | 82637013 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | TCAGACCCAAGGGGATCCAGAGG | CPEB1 | ENSG00000277445 | -0.18966121950357445 | [182] | [120] | -1 | hSpCas9 | negative selection | 36258 | 82636944 | 82636967 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | CAGGCGTGATCCTCTAACTGAGG | CPEB1 | ENSG00000277445 | -0.5472620411136826 | [373] | [192] | -4 | hSpCas9 | negative selection | 36259 | 82635003 | 82635026 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | GGTCTTTGGGAGCTTCGAGGAGG | CPEB1 | ENSG00000277445 | 0.27941983430750084 | [176] | [161] | 2 | hSpCas9 | negative selection | 36260 | 82633045 | 82633068 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Jiyoye | viability | CTGGCCACTCCAGGTACAGGTGG | CPEB1 | ENSG00000277445 | -1.0309457308860117 | [83] | [30] | -6 | hSpCas9 | negative selection | 36261 | 82635183 | 82635206 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | GCAGAGGTGGAGAAATGCGAAGG | CPEB1 | ENSG00000277445 | -0.6367401601824823 | [182,226] | [53,70] | -5 | hSpCas9 | negative selection | 227368 | 82628699 | 82628722 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | GCTCCGGACAAAGTTACTGTCGG | CPEB1 | ENSG00000277445 | -0.582968528647956 | [387,444] | [107,153] | -5 | hSpCas9 | negative selection | 227369 | 82650548 | 82650571 | CHR_HSCHR15_5_CTG8 | - | 26472758 | KBM7 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000277445 | -0.42127935002464456 | [1882,1447] | [620,542] | -4 | hSpCas9 | negative selection | 227370 | 82571460 | 82571483 | 15 | - | 26472758 | KBM7 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.42127935002464456 | [1882,1447] | [620,542] | -4 | hSpCas9 | negative selection | 227371 | 82635167 | 82635190 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | GACAGAGACAGGAAGGGCAGAGG | CPEB1 | ENSG00000277445 | -1.065037237816122 | [529,439] | [136,82] | -7 | hSpCas9 | negative selection | 227372 | 82633019 | 82633042 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | GGGTTCTTATAGTTCCGGGGAGG | CPEB1 | ENSG00000277445 | -0.6150843995096387 | [581,262] | [156,96] | -5 | hSpCas9 | negative selection | 227373 | 82650501 | 82650524 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000277445 | 0.5409942103764505 | [899,469] | [486,427] | 6 | hSpCas9 | negative selection | 227374 | 82571413 | 82571436 | 15 | + | 26472758 | KBM7 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.5409942103764505 | [899,469] | [486,427] | 6 | hSpCas9 | negative selection | 227375 | 82636990 | 82637013 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | TCAGACCCAAGGGGATCCAGAGG | CPEB1 | ENSG00000277445 | -0.19266255414435107 | [638,674] | [255,286] | -2 | hSpCas9 | negative selection | 227376 | 82636944 | 82636967 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | CAGGCGTGATCCTCTAACTGAGG | CPEB1 | ENSG00000277445 | -0.09081430851091898 | [1163,1079] | [450,535] | -1 | hSpCas9 | negative selection | 227377 | 82635003 | 82635026 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | GGTCTTTGGGAGCTTCGAGGAGG | CPEB1 | ENSG00000277445 | -0.07874796965341191 | [1124,970] | [439,487] | -1 | hSpCas9 | negative selection | 227378 | 82633045 | 82633068 | CHR_HSCHR15_5_CTG8 | + | 26472758 | KBM7 | viability | CTGGCCACTCCAGGTACAGGTGG | CPEB1 | ENSG00000277445 | 0.5879520513414851 | [66,126] | [69,71] | 6 | hSpCas9 | negative selection | 227379 | 82635183 | 82635206 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | GCAGAGGTGGAGAAATGCGAAGG | CPEB1 | ENSG00000277445 | 0.034134553342960894 | [100] | [23] | 0 | hSpCas9 | negative selection | 418486 | 82628699 | 82628722 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | GCTCCGGACAAAGTTACTGTCGG | CPEB1 | ENSG00000277445 | -1.0004197541609157 | [249] | [28] | -6 | hSpCas9 | negative selection | 418487 | 82650548 | 82650571 | CHR_HSCHR15_5_CTG8 | - | 26472758 | Raji | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000277445 | 0.4143034177971332 | [830] | [256] | 4 | hSpCas9 | negative selection | 418488 | 82571460 | 82571483 | 15 | - | 26472758 | Raji | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.4143034177971332 | [830] | [256] | 4 | hSpCas9 | negative selection | 418489 | 82635167 | 82635190 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | GACAGAGACAGGAAGGGCAGAGG | CPEB1 | ENSG00000277445 | -4.021899481571367 | [209] | [2] | -9 | hSpCas9 | negative selection | 418490 | 82633019 | 82633042 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | GGGTTCTTATAGTTCCGGGGAGG | CPEB1 | ENSG00000277445 | 0.2434450849496279 | [272] | [74] | 2 | hSpCas9 | negative selection | 418491 | 82650501 | 82650524 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000277445 | 0.5880093762800201 | [257] | [89] | 5 | hSpCas9 | negative selection | 418492 | 82571413 | 82571436 | 15 | + | 26472758 | Raji | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.5880093762800201 | [257] | [89] | 5 | hSpCas9 | negative selection | 418493 | 82636990 | 82637013 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | TCAGACCCAAGGGGATCCAGAGG | CPEB1 | ENSG00000277445 | -0.5971605811002293 | [351] | [53] | -5 | hSpCas9 | negative selection | 418494 | 82636944 | 82636967 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | CAGGCGTGATCCTCTAACTGAGG | CPEB1 | ENSG00000277445 | 0.18237702466172245 | [580] | [152] | 1 | hSpCas9 | negative selection | 418495 | 82635003 | 82635026 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | GGTCTTTGGGAGCTTCGAGGAGG | CPEB1 | ENSG00000277445 | -0.6170683050213353 | [726] | [109] | -5 | hSpCas9 | negative selection | 418496 | 82633045 | 82633068 | CHR_HSCHR15_5_CTG8 | + | 26472758 | Raji | viability | CTGGCCACTCCAGGTACAGGTGG | CPEB1 | ENSG00000277445 | 2.2542249237028704 | [27] | [30] | 9 | hSpCas9 | negative selection | 418497 | 82635183 | 82635206 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | GCAGAGGTGGAGAAATGCGAAGG | CPEB1 | ENSG00000277445 | -0.7066716718526065 | [173] | [89] | -4 | hSpCas9 | negative selection | 609604 | 82628699 | 82628722 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | GCTCCGGACAAAGTTACTGTCGG | CPEB1 | ENSG00000277445 | -1.1135376764051295 | [445] | [173] | -6 | hSpCas9 | negative selection | 609605 | 82650548 | 82650571 | CHR_HSCHR15_5_CTG8 | - | 26472758 | K562 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000277445 | -0.04280827611591298 | [1334] | [1093] | 0 | hSpCas9 | negative selection | 609606 | 82571460 | 82571483 | 15 | - | 26472758 | K562 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.04280827611591298 | [1334] | [1093] | 0 | hSpCas9 | negative selection | 609607 | 82635167 | 82635190 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | GACAGAGACAGGAAGGGCAGAGG | CPEB1 | ENSG00000277445 | -4.223186822416551 | [353] | [15] | -9 | hSpCas9 | negative selection | 609608 | 82633019 | 82633042 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | GGGTTCTTATAGTTCCGGGGAGG | CPEB1 | ENSG00000277445 | 0.24441872766644673 | [394] | [394] | 1 | hSpCas9 | negative selection | 609609 | 82650501 | 82650524 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000277445 | 0.4713838787927189 | [404] | [473] | 4 | hSpCas9 | negative selection | 609610 | 82571413 | 82571436 | 15 | + | 26472758 | K562 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.4713838787927189 | [404] | [473] | 4 | hSpCas9 | negative selection | 609611 | 82636990 | 82637013 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | TCAGACCCAAGGGGATCCAGAGG | CPEB1 | ENSG00000277445 | -0.6856017427806269 | [502] | [263] | -4 | hSpCas9 | negative selection | 609612 | 82636944 | 82636967 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | CAGGCGTGATCCTCTAACTGAGG | CPEB1 | ENSG00000277445 | 0.25417769412877544 | [883] | [889] | 2 | hSpCas9 | negative selection | 609613 | 82635003 | 82635026 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | GGTCTTTGGGAGCTTCGAGGAGG | CPEB1 | ENSG00000277445 | 0.14232054004771055 | [965] | [899] | 1 | hSpCas9 | negative selection | 609614 | 82633045 | 82633068 | CHR_HSCHR15_5_CTG8 | + | 26472758 | K562 | viability | CTGGCCACTCCAGGTACAGGTGG | CPEB1 | ENSG00000277445 | 0.10559102296913014 | [108] | [98] | 0 | hSpCas9 | negative selection | 609615 | 82571413 | 82571436 | 15 | + | 26627737 | DLD1 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.581013686364966 | [609] | [247,83,58] | -5 | hSpCas9 | negative selection | 792086 | 82573093 | 82573116 | 15 | + | 26627737 | DLD1 | viability | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.34421957473388365 | [729] | [385,301,195] | 3 | hSpCas9 | negative selection | 792087 | 82627297 | 82627320 | 15 | + | 26627737 | DLD1 | viability | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.04679025726230435 | [795] | [210,332,233] | 0 | hSpCas9 | negative selection | 792088 | 82571413 | 82571436 | 15 | + | 26627737 | GBM cells | viability after 5 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.7720838526502027 | [100] | [111,72] | 9 | hSpCas9 | negative selection | 874401 | 82573093 | 82573116 | 15 | + | 26627737 | GBM cells | viability after 5 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.41957513603490576 | [418] | [194,140] | -6 | hSpCas9 | negative selection | 874402 | 82627297 | 82627320 | 15 | + | 26627737 | GBM cells | viability after 5 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.25580733181054516 | [480] | [266,348] | 4 | hSpCas9 | negative selection | 874403 | 82571413 | 82571436 | 15 | + | 26627737 | GBM cells | viability after 13 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.6698802115550476 | [100] | [111,66] | 7 | hSpCas9 | negative selection | 956716 | 82573093 | 82573116 | 15 | + | 26627737 | GBM cells | viability after 13 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.5551133743878337 | [418] | [162,147] | -6 | hSpCas9 | negative selection | 956717 | 82627297 | 82627320 | 15 | + | 26627737 | GBM cells | viability after 13 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.35448439533863785 | [480] | [363,308] | 4 | hSpCas9 | negative selection | 956718 | 82571413 | 82571436 | 15 | + | 26627737 | GBM cells | viability after 21 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.2274878996721197 | [100] | [49,43] | -2 | hSpCas9 | negative selection | 1039031 | 82573093 | 82573116 | 15 | + | 26627737 | GBM cells | viability after 21 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.8285707811725453 | [418] | [123,131] | -6 | hSpCas9 | negative selection | 1039032 | 82627297 | 82627320 | 15 | + | 26627737 | GBM cells | viability after 21 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.06503374232244652 | [480] | [299,248] | 0 | hSpCas9 | negative selection | 1039033 | 82571413 | 82571436 | 15 | + | 26627737 | RPE1 | viability after 9 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.540924764502742 | [402] | [70,106] | -4 | hSpCas9 | negative selection | 1121346 | 82573093 | 82573116 | 15 | + | 26627737 | RPE1 | viability after 9 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.7828509670906002 | [1584] | [180,426] | -5 | hSpCas9 | negative selection | 1121347 | 82627297 | 82627320 | 15 | + | 26627737 | RPE1 | viability after 9 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.07430083762429196 | [1756] | [404,673] | 0 | hSpCas9 | negative selection | 1121348 | 82571413 | 82571436 | 15 | + | 26627737 | RPE1 | viability after 12 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.4641664387239399 | [402] | [60,96] | -3 | hSpCas9 | negative selection | 1203661 | 82573093 | 82573116 | 15 | + | 26627737 | RPE1 | viability after 12 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -1.6622337229990705 | [1584] | [135,132] | -8 | hSpCas9 | negative selection | 1203662 | 82627297 | 82627320 | 15 | + | 26627737 | RPE1 | viability after 12 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.05297373899823854 | [1756] | [370,543] | 0 | hSpCas9 | negative selection | 1203663 | 82571413 | 82571436 | 15 | + | 26627737 | RPE1 | viability after 15 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.7765743453168543 | [402] | [91,41] | -5 | hSpCas9 | negative selection | 1285976 | 82573093 | 82573116 | 15 | + | 26627737 | RPE1 | viability after 15 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -1.431435342071275 | [1584] | [152,178] | -7 | hSpCas9 | negative selection | 1285977 | 82627297 | 82627320 | 15 | + | 26627737 | RPE1 | viability after 15 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.04903551949416429 | [1756] | [344,610] | 0 | hSpCas9 | negative selection | 1285978 | 82571413 | 82571436 | 15 | + | 26627737 | RPE1 | viability after 18 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -3.0027550021350566 | [402] | [0,26] | -9 | hSpCas9 | negative selection | 1368291 | 82573093 | 82573116 | 15 | + | 26627737 | RPE1 | viability after 18 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -1.0593854378368737 | [1584] | [226,181] | -6 | hSpCas9 | negative selection | 1368292 | 82627297 | 82627320 | 15 | + | 26627737 | RPE1 | viability after 18 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.0053002323532787 | [1756] | [341,618] | 0 | hSpCas9 | negative selection | 1368293 | 82571413 | 82571436 | 15 | + | 26627737 | HeLa | viability after 8 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.5145522705427729 | [244] | [31,165,226] | 4 | hSpCas9 | negative selection | 1450606 | 82573093 | 82573116 | 15 | + | 26627737 | HeLa | viability after 8 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.06696700682215706 | [531] | [264,87,312] | 0 | hSpCas9 | negative selection | 1450607 | 82627297 | 82627320 | 15 | + | 26627737 | HeLa | viability after 8 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.16935295973987086 | [594] | [293,346,236] | 1 | hSpCas9 | negative selection | 1450608 | 82571413 | 82571436 | 15 | + | 26627737 | HeLa | viability after 12 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.6180932955518996 | [244] | [17,298,129] | 5 | hSpCas9 | negative selection | 1532921 | 82573093 | 82573116 | 15 | + | 26627737 | HeLa | viability after 12 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.4761323702658531 | [531] | [469,175,289] | 4 | hSpCas9 | negative selection | 1532922 | 82627297 | 82627320 | 15 | + | 26627737 | HeLa | viability after 12 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.34884926323799115 | [594] | [370,323,244] | 3 | hSpCas9 | negative selection | 1532923 | 82571413 | 82571436 | 15 | + | 26627737 | HeLa | viability after 15 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.179464728410981 | [244] | [77,346,256] | 8 | hSpCas9 | negative selection | 1615236 | 82573093 | 82573116 | 15 | + | 26627737 | HeLa | viability after 15 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.7781906228198374 | [531] | [307,291,526] | 6 | hSpCas9 | negative selection | 1615237 | 82627297 | 82627320 | 15 | + | 26627737 | HeLa | viability after 15 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.7569585483293885 | [594] | [83,248,93] | -6 | hSpCas9 | negative selection | 1615238 | 82571413 | 82571436 | 15 | + | 26627737 | HeLa | viability after 18 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.1529727131682348 | [244] | [46,283,256] | 7 | hSpCas9 | negative selection | 1697551 | 82573093 | 82573116 | 15 | + | 26627737 | HeLa | viability after 18 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.7744220066323664 | [531] | [194,253,526] | 6 | hSpCas9 | negative selection | 1697552 | 82627297 | 82627320 | 15 | + | 26627737 | HeLa | viability after 18 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.6917255888380475 | [594] | [58,218,93] | -6 | hSpCas9 | negative selection | 1697553 | 82571413 | 82571436 | 15 | + | 26627737 | HCT116 | viability after 6 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.7308078181379908 | [723] | [172,10] | -4 | hSpCas9 | negative selection | 1779866 | 82573093 | 82573116 | 15 | + | 26627737 | HCT116 | viability after 6 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 1.3098310971709242 | [784] | [245,338] | 7 | hSpCas9 | negative selection | 1779867 | 82627297 | 82627320 | 15 | + | 26627737 | HCT116 | viability after 6 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.14673373482590857 | [1240] | [195,226] | 0 | hSpCas9 | negative selection | 1779868 | 82571413 | 82571436 | 15 | + | 26627737 | HCT116 | viability after 8 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.7734378526460876 | [132] | [118,155,100] | 7 | hSpCas9 | negative selection | 1862181 | 82573093 | 82573116 | 15 | + | 26627737 | HCT116 | viability after 8 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.10078009674601196 | [465] | [217,179,318] | -1 | hSpCas9 | negative selection | 1862182 | 82627297 | 82627320 | 15 | + | 26627737 | HCT116 | viability after 8 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.23253113030917694 | [499] | [323,314,331] | 2 | hSpCas9 | negative selection | 1862183 | 82571413 | 82571436 | 15 | + | 26627737 | HCT116 | viability after 9 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -1.107486771296105 | [723] | [182,15] | -7 | hSpCas9 | negative selection | 1944496 | 82573093 | 82573116 | 15 | + | 26627737 | HCT116 | viability after 9 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.08729949639430695 | [784] | [177,257] | 0 | hSpCas9 | negative selection | 1944497 | 82627297 | 82627320 | 15 | + | 26627737 | HCT116 | viability after 9 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.39633381990484917 | [1240] | [410,455] | 3 | hSpCas9 | negative selection | 1944498 | 82571413 | 82571436 | 15 | + | 26627737 | HCT116 | viability after 12 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.3016678300304728 | [132] | [83,100,73] | 3 | hSpCas9 | negative selection | 2026811 | 82573093 | 82573116 | 15 | + | 26627737 | HCT116 | viability after 12 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.20956981596575064 | [465] | [133,379,350] | 2 | hSpCas9 | negative selection | 2026812 | 82627297 | 82627320 | 15 | + | 26627737 | HCT116 | viability after 12 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.27569255942070126 | [499] | [349,256,342] | 3 | hSpCas9 | negative selection | 2026813 | 82571413 | 82571436 | 15 | + | 26627737 | HCT116 | viability after 15 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.31570748513913083 | [132] | [129,45,16] | -3 | hSpCas9 | negative selection | 2109126 | 82573093 | 82573116 | 15 | + | 26627737 | HCT116 | viability after 15 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.12377172795239832 | [465] | [336,391,152] | 1 | hSpCas9 | negative selection | 2109127 | 82627297 | 82627320 | 15 | + | 26627737 | HCT116 | viability after 15 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.3774773509328885 | [499] | [405,253,461] | 3 | hSpCas9 | negative selection | 2109128 | 82571413 | 82571436 | 15 | + | 26627737 | HCT116 | viability after 18 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.046033740185383865 | [132] | [43,93,58] | 0 | hSpCas9 | negative selection | 2191441 | 82573093 | 82573116 | 15 | + | 26627737 | HCT116 | viability after 18 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.33709171043747294 | [465] | [190,241,93] | -3 | hSpCas9 | negative selection | 2191442 | 82627297 | 82627320 | 15 | + | 26627737 | HCT116 | viability after 18 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.5677958673221698 | [499] | [495,240,344] | 5 | hSpCas9 | negative selection | 2191443 | 82571943 | 82571966 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGGTGCAGTGCCGTTAAGTCTGG | CPEB1 | ENSG00000214575 | 4.731673143246815 | [267,136] | [2264,14] | 9 | dCas9-VP64 | positive selection | 2393040 | 82651031 | 82651054 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGGTGCAGTGCCGTTAAGTCTGG | CPEB1 | ENSG00000277445 | 4.731673143246815 | [267,136] | [2264,14] | 9 | dCas9-VP64 | positive selection | 2393041 | 82571905 | 82571928 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCTGTTGTGCTGTCTTTCCCTGG | CPEB1 | ENSG00000214575 | 0.30163105145925584 | [196,101] | [25,54] | 1 | dCas9-VP64 | positive selection | 2393042 | 82650993 | 82651016 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCTGTTGTGCTGTCTTTCCCTGG | CPEB1 | ENSG00000277445 | 0.30163105145925584 | [196,101] | [25,54] | 1 | dCas9-VP64 | positive selection | 2393043 | 82571965 | 82571988 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGTTGCAAGGCAGCGCCCTCCGG | CPEB1 | ENSG00000214575 | 0.7971894539294658 | [41,143] | [11,60] | 3 | dCas9-VP64 | positive selection | 2393044 | 82651053 | 82651076 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGTTGCAAGGCAGCGCCCTCCGG | CPEB1 | ENSG00000277445 | 0.7971894539294658 | [41,143] | [11,60] | 3 | dCas9-VP64 | positive selection | 2393045 | 82653713 | 82653736 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCAGGAGAATTGCTTGAGCCCAG | CPEB1 | ENSG00000277445 | 2.347530044627342 | [92,62] | [38,139] | 7 | dCas9-VP64 | positive selection | 2400866 | 82574625 | 82574648 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCAGGAGAATTGCTTGAGCCCAG | CPEB1 | ENSG00000214575 | 2.347530044627342 | [92,62] | [38,139] | 7 | dCas9-VP64 | positive selection | 2400867 | 82647686 | 82647709 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGGCGTGGGGCCTCGTGGAGGGG | CPEB1 | ENSG00000214575 | 3.4960071954920893 | [122,304] | [133,971] | 9 | dCas9-VP64 | positive selection | 2425751 | 82677284 | 82677307 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGCGTGAGCCACCGCACCTAG | CPEB1 | ENSG00000277445 | 0.9167831099864405 | [164,216] | [6,157] | 4 | dCas9-VP64 | positive selection | 2444428 | 82598196 | 82598219 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGCGTGAGCCACCGCACCTAG | CPEB1 | ENSG00000214575 | 0.9167831099864405 | [164,216] | [6,157] | 4 | dCas9-VP64 | positive selection | 2444429 | 82612757 | 82612780 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTACTGCAACCTCCGCCCCCCAG | CPEB1 | ENSG00000214575 | -1.8511650686779566 | [352,350] | [21,19] | -8 | dCas9-VP64 | positive selection | 2452189 | 82691846 | 82691869 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTACTGCAACCTCCGCCCCCCAG | CPEB1 | ENSG00000277445 | -1.8511650686779566 | [352,350] | [21,19] | -8 | dCas9-VP64 | positive selection | 2452190 | 82578937 | 82578960 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCAGCTACTCGGGAGGCTGGAG | CPEB1 | ENSG00000214575 | -0.4892893999709095 | [44,388] | [14,54] | -2 | dCas9-VP64 | positive selection | 2465821 | 82658025 | 82658048 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCAGCTACTCGGGAGGCTGGAG | CPEB1 | ENSG00000277445 | -0.4892893999709095 | [44,388] | [14,54] | -2 | dCas9-VP64 | positive selection | 2465822 | 82681838 | 82681861 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGAAGAATCGCTTGAACCCGGG | CPEB1 | ENSG00000277445 | 0.6947743245442068 | [118,16] | [8,38] | 3 | dCas9-VP64 | positive selection | 2469044 | 82602751 | 82602774 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGAAGAATCGCTTGAACCCGGG | CPEB1 | ENSG00000214575 | 0.6947743245442068 | [118,16] | [8,38] | 3 | dCas9-VP64 | positive selection | 2469045 | 82571943 | 82571966 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGGTGCAGTGCCGTTAAGTCTGG | CPEB1 | ENSG00000214575 | -0.12645089127652964 | [410,526] | [174,105] | -1 | dCas9-VP64 | positive selection | 2488295 | 82651031 | 82651054 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGGTGCAGTGCCGTTAAGTCTGG | CPEB1 | ENSG00000277445 | -0.12645089127652964 | [410,526] | [174,105] | -1 | dCas9-VP64 | positive selection | 2488296 | 82571905 | 82571928 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCTGTTGTGCTGTCTTTCCCTGG | CPEB1 | ENSG00000214575 | 0.9141130619101066 | [305,276] | [97,255] | 6 | dCas9-VP64 | positive selection | 2488297 | 82650993 | 82651016 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCTGTTGTGCTGTCTTTCCCTGG | CPEB1 | ENSG00000277445 | 0.9141130619101066 | [305,276] | [97,255] | 6 | dCas9-VP64 | positive selection | 2488298 | 82571965 | 82571988 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGTTGCAAGGCAGCGCCCTCCGG | CPEB1 | ENSG00000214575 | 1.342523763830049 | [205,198] | [69,259] | 7 | dCas9-VP64 | positive selection | 2488299 | 82651053 | 82651076 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGTTGCAAGGCAGCGCCCTCCGG | CPEB1 | ENSG00000277445 | 1.342523763830049 | [205,198] | [69,259] | 7 | dCas9-VP64 | positive selection | 2488300 | 82653713 | 82653736 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCAGGAGAATTGCTTGAGCCCAG | CPEB1 | ENSG00000277445 | -0.44752543583137055 | [210,198] | [66,31] | -5 | dCas9-VP64 | positive selection | 2496121 | 82574625 | 82574648 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCAGGAGAATTGCTTGAGCCCAG | CPEB1 | ENSG00000214575 | -0.44752543583137055 | [210,198] | [66,31] | -5 | dCas9-VP64 | positive selection | 2496122 | 82647686 | 82647709 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGGCGTGGGGCCTCGTGGAGGGG | CPEB1 | ENSG00000214575 | 0.3955602782029617 | [118,107] | [29,65] | 3 | dCas9-VP64 | positive selection | 2521006 | 82677284 | 82677307 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGCGTGAGCCACCGCACCTAG | CPEB1 | ENSG00000277445 | 0.9421040719499846 | [89,134] | [114,27] | 6 | dCas9-VP64 | positive selection | 2539683 | 82598196 | 82598219 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGCGTGAGCCACCGCACCTAG | CPEB1 | ENSG00000214575 | 0.9421040719499846 | [89,134] | [114,27] | 6 | dCas9-VP64 | positive selection | 2539684 | 82612757 | 82612780 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTACTGCAACCTCCGCCCCCCAG | CPEB1 | ENSG00000214575 | 0.9477034237395038 | [173,106] | [127,52] | 6 | dCas9-VP64 | positive selection | 2547444 | 82691846 | 82691869 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTACTGCAACCTCCGCCCCCCAG | CPEB1 | ENSG00000277445 | 0.9477034237395038 | [173,106] | [127,52] | 6 | dCas9-VP64 | positive selection | 2547445 | 82578937 | 82578960 | 15 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCAGCTACTCGGGAGGCTGGAG | CPEB1 | ENSG00000214575 | -0.16148281958930955 | [134,276] | [52,65] | -1 | dCas9-VP64 | positive selection | 2561076 | 82658025 | 82658048 | CHR_HSCHR15_5_CTG8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCAGCTACTCGGGAGGCTGGAG | CPEB1 | ENSG00000277445 | -0.16148281958930955 | [134,276] | [52,65] | -1 | dCas9-VP64 | positive selection | 2561077 | 82681838 | 82681861 | CHR_HSCHR15_5_CTG8 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGAAGAATCGCTTGAACCCGGG | CPEB1 | ENSG00000277445 | -1.217410828372933 | [137,230] | [25,24] | -9 | dCas9-VP64 | positive selection | 2564299 | 82602751 | 82602774 | 15 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGAAGAATCGCTTGAACCCGGG | CPEB1 | ENSG00000214575 | -1.217410828372933 | [137,230] | [25,24] | -9 | dCas9-VP64 | positive selection | 2564300 | 82571463 | 82571486 | 15 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.13093905800418118 | [4,4] | [4,3] | 2 | hSpCas9 | positive selection | 2980831 | 82571460 | 82571483 | 15 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.1650635404301748 | [3,3] | [1,4] | 3 | hSpCas9 | positive selection | 2980832 | 82571463 | 82571486 | 15 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.3220627018281965 | [4,4] | [5,2] | 5 | hSpCas9 | positive selection | 3048689 | 82571460 | 82571483 | 15 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.4451181656150834 | [3,3] | [2,3] | 7 | hSpCas9 | positive selection | 3048690 | 82571462 | 82571485 | | + | 24336571 | A375 | resistance to PLX after 7 days | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.008153681463105356 | [11,18] | [14,15] | 0 | hSpCas9 | positive selection | 3107085 | 82571462 | 82571485 | | + | 24336571 | A375 | resistance to PLX after 14 days | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.27727564308292685 | [11,19] | [5,4] | -3 | hSpCas9 | positive selection | 3164878 | 82571462 | 82571485 | | + | 24336571 | A375 | viability after 7 days | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.2540556546085102 | [19] | [11,18] | -4 | hSpCas9 | negative selection | 3222671 | 82571462 | 82571485 | | + | 24336571 | A375 | viability after 14 days | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.16672173938349727 | [19] | [11,19] | -2 | hSpCas9 | negative selection | 3280464 | 82571462 | 82571485 | 15 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 3.662157639574217 | [134,215] | [0,27] | 9 | hSpCas9 | positive selection | 3344339 | 82571460 | 82571483 | 15 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.004258926994840487 | [158,145] | [0,0] | 0 | hSpCas9 | positive selection | 3344340 | 82571462 | 82571485 | 15 | + | 26780180 | HT29 | viability (Avana library 4 designs) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 1.09819912041798 | [] | [] | 4 | hSpCas9 | negative selection | 3417301 | 82571460 | 82571483 | 15 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 1.74255594361137 | [] | [] | 6 | hSpCas9 | negative selection | 3417302 | 82571460 | 82571483 | 15 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.977014348230228 | [] | [] | -1 | hSpCas9 | negative selection | 3495239 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 2.74710550984396 | [] | [] | 4 | hSpCas9 | negative selection | 3495240 | 82571460 | 82571483 | 15 | - | 26780180 | A375 | viability (Avana lentiGuide) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.202405811040576 | [] | [] | 0 | hSpCas9 | negative selection | 3603898 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | viability (Avana lentiGuide) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 2.58687002432705 | [] | [] | 2 | hSpCas9 | negative selection | 3603899 | 82571460 | 82571483 | 15 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.04960356053259699 | [5] | [5,4] | -1 | hSpCas9 | positive selection | 3712557 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.050219809647350566 | [6] | [5,6] | 1 | hSpCas9 | positive selection | 3712558 | 82571460 | 82571483 | 15 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.10462889867111486 | [5] | [4,5] | 2 | hSpCas9 | positive selection | 3821164 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.12524939909203325 | [6] | [6,5] | 3 | hSpCas9 | positive selection | 3821165 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 1.34963819623013 | [] | [] | 7 | hSpCas9 | negative selection | 3929198 | 82571460 | 82571483 | 15 | - | 26780180 | A375 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.970035469532189 | [] | [] | 4 | hSpCas9 | negative selection | 3929199 | 82571462 | 82571485 | 15 | + | 26780180 | HT29 | viability (GeCKOv2 library) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.536960300303739 | [] | [] | 1 | hSpCas9 | negative selection | 4037164 | 82571460 | 82571483 | 15 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.497093035580374 | [] | [] | 1 | hSpCas9 | negative selection | 4037165 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.1922425761802799 | [4] | [2,2] | -4 | hSpCas9 | positive selection | 4129318 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.42224485374670284 | [4] | [0,4,0,0] | -6 | hSpCas9 | positive selection | 4193340 | 82571462 | 82571485 | 15 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.018897036621012525 | [3] | [2,2] | 0 | hSpCas9 | positive selection | 4264613 | 82571460 | 82571483 | 15 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.1354912175811305 | [2] | [2,1] | -3 | hSpCas9 | positive selection | 4264614 | 82647584 | 82647607 | 15 | + | 27661255 | K562 | viability | GTGCGGCTCGGAGGCCCCACCGG | CPEB1 | ENSG00000214575 | 0.10285918521851306 | [730,868] | [722,650] | 3 | dCas9-KRAB | negative selection | 5472471 | 82647518 | 82647541 | 15 | - | 27661255 | K562 | viability | GACCGGACATAAAGGAGCACCGG | CPEB1 | ENSG00000214575 | -0.008189544841654017 | [1461,1314] | [1125,1086] | 0 | dCas9-KRAB | negative selection | 5472472 | 82647688 | 82647711 | 15 | - | 27661255 | K562 | viability | GCGGGCGTGGGGCCTCGTGGAGG | CPEB1 | ENSG00000214575 | -4.242334449351155 | [228,214] | [10,7] | -9 | dCas9-KRAB | negative selection | 5472473 | 82571462 | 82571485 | 15 | + | 27260156 | BXPC3 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.08226424216026185 | [809] | [765,695,859,894] | -2 | hSpCas9 | negative selection | 5537073 | 82571460 | 82571483 | 15 | - | 27260156 | BXPC3 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.09770368475016365 | [444] | [459,363,449,467] | -2 | hSpCas9 | negative selection | 5537074 | 82571462 | 82571485 | 15 | + | 27260156 | A673 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.12065115150232097 | [809] | [1058,1064,982,1124] | 3 | hSpCas9 | negative selection | 5658324 | 82571460 | 82571483 | 15 | - | 27260156 | A673 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.1624208918531594 | [444] | [624,529,660,577] | 4 | hSpCas9 | negative selection | 5658325 | 82571462 | 82571485 | 15 | + | 27260156 | A375 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.42342060205249915 | [809] | [472,971,681,724] | -5 | hSpCas9 | negative selection | 5779575 | 82571460 | 82571483 | 15 | - | 27260156 | A375 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.12230792324605182 | [444] | [578,496,490,358] | -2 | hSpCas9 | negative selection | 5779576 | 82571462 | 82571485 | 15 | + | 27260156 | COLO741 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.46735470460006623 | [809] | [763,881,609] | -7 | hSpCas9 | negative selection | 5900826 | 82571460 | 82571483 | 15 | - | 27260156 | COLO741 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.42829484865904255 | [444] | [473,305,485] | -7 | hSpCas9 | negative selection | 5900827 | 82571462 | 82571485 | 15 | + | 27260156 | CAL120 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.00044065835846374135 | [809] | [1318,945,807] | 0 | hSpCas9 | negative selection | 6022077 | 82571460 | 82571483 | 15 | - | 27260156 | CAL120 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.22080836662095948 | [444] | [926,566,486] | 3 | hSpCas9 | negative selection | 6022078 | 82571462 | 82571485 | 15 | + | 27260156 | CADOES1 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.14319846818558424 | [809] | [706,459,880,679] | -2 | hSpCas9 | negative selection | 6143328 | 82571460 | 82571483 | 15 | - | 27260156 | CADOES1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.23150479917313943 | [444] | [282,356,270,504] | -4 | hSpCas9 | negative selection | 6143329 | 82571462 | 82571485 | 15 | + | 27260156 | EWS502 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.06716361580904529 | [809] | [686,900,813,887] | -1 | hSpCas9 | negative selection | 6264579 | 82571460 | 82571483 | 15 | - | 27260156 | EWS502 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.2573651632749689 | [444] | [430,407,351,377] | -4 | hSpCas9 | negative selection | 6264580 | 82571462 | 82571485 | 15 | + | 27260156 | EW8 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.05283063729127513 | [809] | [821,527,518,699] | -1 | hSpCas9 | negative selection | 6385830 | 82571460 | 82571483 | 15 | - | 27260156 | EW8 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.017180013755855914 | [444] | [533,329,261,333] | 0 | hSpCas9 | negative selection | 6385831 | 82571462 | 82571485 | 15 | + | 27260156 | CORL105 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.16999127528333324 | [809] | [970,874,826,699] | -3 | hSpCas9 | negative selection | 6507081 | 82571460 | 82571483 | 15 | - | 27260156 | CORL105 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.026574355267448224 | [444] | [522,356,714,485] | 0 | hSpCas9 | negative selection | 6507082 | 82571462 | 82571485 | 15 | + | 27260156 | HS294T | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.10558794147769579 | [809] | [221,446,338,347] | 1 | hSpCas9 | negative selection | 6628332 | 82571460 | 82571483 | 15 | - | 27260156 | HS294T | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.00850127164869055 | [444] | [114,212,164,208] | 0 | hSpCas9 | negative selection | 6628333 | 82571462 | 82571485 | 15 | + | 27260156 | HCC44 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.19553208294893465 | [809] | [834,671,973,764] | -3 | hSpCas9 | negative selection | 6749583 | 82571460 | 82571483 | 15 | - | 27260156 | HCC44 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.33092678223038363 | [444] | [284,448,413,432] | -5 | hSpCas9 | negative selection | 6749584 | 82571462 | 82571485 | 15 | + | 27260156 | G402 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.1118573026666847 | [809] | [903,856,447,1977] | 1 | hSpCas9 | negative selection | 6870834 | 82571460 | 82571483 | 15 | - | 27260156 | G402 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.08365361822138272 | [444] | [471,581,552,672] | 1 | hSpCas9 | negative selection | 6870835 | 82571462 | 82571485 | 15 | + | 27260156 | L33 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.021186768071302042 | [809] | [769,320,499,843] | 0 | hSpCas9 | negative selection | 6992085 | 82571460 | 82571483 | 15 | - | 27260156 | L33 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.037765395993492816 | [444] | [345,187,343,477] | 0 | hSpCas9 | negative selection | 6992086 | 82571462 | 82571485 | 15 | + | 27260156 | K562 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.4340134292857149 | [809] | [525,569,607,434] | -5 | hSpCas9 | negative selection | 7113336 | 82571460 | 82571483 | 15 | - | 27260156 | K562 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.050413239995038786 | [444] | [308,471,380,460] | 0 | hSpCas9 | negative selection | 7113337 | 82571462 | 82571485 | 15 | + | 27260156 | HT29 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.016629710881988502 | [809] | [935,1269,855,860] | 0 | hSpCas9 | negative selection | 7234587 | 82571460 | 82571483 | 15 | - | 27260156 | HT29 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.03381114439206812 | [444] | [654,430,529,587] | 0 | hSpCas9 | negative selection | 7234588 | 82571462 | 82571485 | 15 | + | 27260156 | MHHES1 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.15148177184858258 | [809] | [1106,775,900,571] | -3 | hSpCas9 | negative selection | 7355838 | 82571460 | 82571483 | 15 | - | 27260156 | MHHES1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.1688560837361392 | [444] | [780,662,363,485] | 3 | hSpCas9 | negative selection | 7355839 | 82571462 | 82571485 | 15 | + | 27260156 | MEWO | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.00016670036434107693 | [809] | [1210,612,537] | 0 | hSpCas9 | negative selection | 7477089 | 82571460 | 82571483 | 15 | - | 27260156 | MEWO | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.07368665389075763 | [444] | [594,379,369] | 1 | hSpCas9 | negative selection | 7477090 | 82571462 | 82571485 | 15 | + | 27260156 | LNCAPCLONEFGC | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.29181653951502706 | [809] | [484,568,886,502] | -4 | hSpCas9 | negative selection | 7598340 | 82571460 | 82571483 | 15 | - | 27260156 | LNCAPCLONEFGC | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.10271917730516852 | [444] | [333,553,553,300] | 1 | hSpCas9 | negative selection | 7598341 | 82571462 | 82571485 | 15 | + | 27260156 | PANC0327 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.029553703581379542 | [809] | [825,639,754,616] | 0 | hSpCas9 | negative selection | 7719591 | 82571460 | 82571483 | 15 | - | 27260156 | PANC0327 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.20136597548538876 | [444] | [435,479,415,480] | 3 | hSpCas9 | negative selection | 7719592 | 82571462 | 82571485 | 15 | + | 27260156 | NCIH2009 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.28325031883551155 | [809] | [1072,795,949] | -4 | hSpCas9 | negative selection | 7840842 | 82571460 | 82571483 | 15 | - | 27260156 | NCIH2009 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.07894962711413316 | [444] | [757,497,543] | -1 | hSpCas9 | negative selection | 7840843 | 82571462 | 82571485 | 15 | + | 27260156 | NCIH1373 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.14698077872736137 | [809] | [771,1478,672,62] | -1 | hSpCas9 | negative selection | 7962093 | 82571460 | 82571483 | 15 | - | 27260156 | NCIH1373 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.032390176872576795 | [444] | [538,655,333,106] | 0 | hSpCas9 | negative selection | 7962094 | 82571462 | 82571485 | 15 | + | 27260156 | PATU8902 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.23820126092132432 | [809] | [1163,991,927,708] | -2 | hSpCas9 | negative selection | 8083344 | 82571460 | 82571483 | 15 | - | 27260156 | PATU8902 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.0075435206980373065 | [444] | [642,656,429,831] | 0 | hSpCas9 | negative selection | 8083345 | 82571462 | 82571485 | 15 | + | 27260156 | PANC1 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.11009670781986824 | [809] | [642,815,652,512] | -2 | hSpCas9 | negative selection | 8204595 | 82571460 | 82571483 | 15 | - | 27260156 | PANC1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.5050426544199083 | [444] | [298,240,268,258] | -6 | hSpCas9 | negative selection | 8204596 | 82571462 | 82571485 | 15 | + | 27260156 | PANC0813 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.08204541210163518 | [809] | [926,1036,1088,968] | 1 | hSpCas9 | negative selection | 8325846 | 82571460 | 82571483 | 15 | - | 27260156 | PANC0813 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.17122042130861453 | [444] | [702,355,687,615] | 3 | hSpCas9 | negative selection | 8325847 | 82571462 | 82571485 | 15 | + | 27260156 | RDES | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.293236878290865 | [809] | [625,691,855,904] | -5 | hSpCas9 | negative selection | 8447097 | 82571460 | 82571483 | 15 | - | 27260156 | RDES | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.16206201438174062 | [444] | [316,372,502,701] | -3 | hSpCas9 | negative selection | 8447098 | 82571462 | 82571485 | 15 | + | 27260156 | PC3 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.11633217749534996 | [809] | [385,786,1417,743] | -3 | hSpCas9 | negative selection | 8568348 | 82571460 | 82571483 | 15 | - | 27260156 | PC3 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.05484707057998321 | [444] | [277,310,512,679] | -1 | hSpCas9 | negative selection | 8568349 | 82571462 | 82571485 | 15 | + | 27260156 | PATU8988T | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.09678269348444257 | [809] | [680,932,681,643] | -2 | hSpCas9 | negative selection | 8689599 | 82571460 | 82571483 | 15 | - | 27260156 | PATU8988T | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.35701044131858517 | [444] | [443,271,291,328] | -5 | hSpCas9 | negative selection | 8689600 | 82571462 | 82571485 | 15 | + | 27260156 | T47D | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.02757716480232819 | [809] | [1029,830,893,957] | 0 | hSpCas9 | negative selection | 8810850 | 82571460 | 82571483 | 15 | - | 27260156 | T47D | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.09500743845783473 | [444] | [487,435,471,551] | -2 | hSpCas9 | negative selection | 8810851 | 82571462 | 82571485 | 15 | + | 27260156 | SU8686 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.0015538063845216277 | [809] | [702,631,801,1156] | 0 | hSpCas9 | negative selection | 8932101 | 82571460 | 82571483 | 15 | - | 27260156 | SU8686 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.21120237962107086 | [444] | [339,289,408,522] | -4 | hSpCas9 | negative selection | 8932102 | 82571462 | 82571485 | 15 | + | 27260156 | SKES1 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.10537378412282783 | [809] | [836,933,682,595] | -2 | hSpCas9 | negative selection | 9053352 | 82571460 | 82571483 | 15 | - | 27260156 | SKES1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.04278024037108655 | [444] | [410,574,419,338] | -1 | hSpCas9 | negative selection | 9053353 | 82571462 | 82571485 | 15 | + | 27260156 | TOV112D | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.005721477496332117 | [809] | [601,1050,869,774] | 0 | hSpCas9 | negative selection | 9174603 | 82571460 | 82571483 | 15 | - | 27260156 | TOV112D | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.2226083178344731 | [444] | [679,426,204,254] | -4 | hSpCas9 | negative selection | 9174604 | 82571462 | 82571485 | 15 | + | 27260156 | TC71 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | 0.007953588747319995 | [809] | [934,773,824,963] | 0 | hSpCas9 | negative selection | 9295854 | 82571460 | 82571483 | 15 | - | 27260156 | TC71 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.05996890159539246 | [444] | [426,478,491,598] | 1 | hSpCas9 | negative selection | 9295855 | 82571462 | 82571485 | 15 | + | 27260156 | TC32 | viability | ACGGGAAGATTCTTGCGCAGAGG | CPEB1 | ENSG00000214575 | -0.06509099557375952 | [809] | [578,535,1061,847] | -1 | hSpCas9 | negative selection | 9417105 | 82571460 | 82571483 | 15 | - | 27260156 | TC32 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.1426947751678228 | [444] | [359,459,598,433] | 2 | hSpCas9 | negative selection | 9417106 | 82571413 | 82571436 | 15 | + | 27869803 | HPAFII | viability after 27 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.1002111137540365 | [112] | [104,145,NaN] | 8 | hSpCas9 | negative selection | 9555092 | 82573093 | 82573116 | 15 | + | 27869803 | HPAFII | viability after 27 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.04965577782334307 | [417] | [167,276,NaN] | 0 | hSpCas9 | negative selection | 9555093 | 82627297 | 82627320 | 15 | + | 27869803 | HPAFII | viability after 27 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -1.025782003011132 | [569] | [270,43,NaN] | -6 | hSpCas9 | negative selection | 9555094 | 82571413 | 82571436 | 15 | + | 27869803 | HPAFII | viability after 15 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.5581095531062532 | [112] | [512,260,NaN] | 9 | hSpCas9 | negative selection | 9637541 | 82573093 | 82573116 | 15 | + | 27869803 | HPAFII | viability after 15 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.13692545630681785 | [417] | [628,409,NaN] | 1 | hSpCas9 | negative selection | 9637542 | 82627297 | 82627320 | 15 | + | 27869803 | HPAFII | viability after 15 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.9319500537939556 | [569] | [584,156,NaN] | -7 | hSpCas9 | negative selection | 9637543 | 82571413 | 82571436 | 15 | + | 27869803 | ASPC1 | viability after 36 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.39001579990155466 | [484] | [141,191,68] | -4 | hSpCas9 | negative selection | 9719990 | 82573093 | 82573116 | 15 | + | 27869803 | ASPC1 | viability after 36 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 1.5517189480965992 | [679] | [1258,494,452] | 9 | hSpCas9 | negative selection | 9719991 | 82627297 | 82627320 | 15 | + | 27869803 | ASPC1 | viability after 36 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.8315493178062769 | [1023] | [787,509,622] | 7 | hSpCas9 | negative selection | 9719992 | 82571413 | 82571436 | 15 | + | 27869803 | PATU8988S | viability after 35 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.262415747272768 | [333] | [96,225,NaN] | 3 | hSpCas9 | negative selection | 9802439 | 82573093 | 82573116 | 15 | + | 27869803 | PATU8988S | viability after 35 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.6429719070701743 | [835] | [267,162,NaN] | -6 | hSpCas9 | negative selection | 9802440 | 82627297 | 82627320 | 15 | + | 27869803 | PATU8988S | viability after 35 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | 0.01647680375728533 | [957] | [287,492,NaN] | 0 | hSpCas9 | negative selection | 9802441 | 82571413 | 82571436 | 15 | + | 27869803 | PATU8988S | viability after 31 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.556270497154178 | [333] | [179,215,NaN] | 6 | hSpCas9 | negative selection | 9884888 | 82573093 | 82573116 | 15 | + | 27869803 | PATU8988S | viability after 31 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | -0.489431971867592 | [835] | [269,195,NaN] | -5 | hSpCas9 | negative selection | 9884889 | 82627297 | 82627320 | 15 | + | 27869803 | PATU8988S | viability after 31 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.28211686006181147 | [957] | [252,391,NaN] | -3 | hSpCas9 | negative selection | 9884890 | 82571413 | 82571436 | 15 | + | 27869803 | HPAFII | viability after 35 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.542263705871021 | [112] | [96,244,NaN] | 9 | hSpCas9 | negative selection | 9967337 | 82573093 | 82573116 | 15 | + | 27869803 | HPAFII | viability after 35 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 1.0065179809817177 | [417] | [347,511,NaN] | 6 | hSpCas9 | negative selection | 9967338 | 82627297 | 82627320 | 15 | + | 27869803 | HPAFII | viability after 35 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -1.1729968785677078 | [569] | [198,47,NaN] | -6 | hSpCas9 | negative selection | 9967339 | 82571413 | 82571436 | 15 | + | 27869803 | HPAFII | viability after 31 days | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.4346560056983466 | [112] | [113,233,NaN] | 9 | hSpCas9 | negative selection | 10049786 | 82573093 | 82573116 | 15 | + | 27869803 | HPAFII | viability after 31 days | ACCTGGGACCTCCCATGGCAGGG | CPEB1 | ENSG00000214575 | 0.4721775110711771 | [417] | [278,375,NaN] | 3 | hSpCas9 | negative selection | 10049787 | 82627297 | 82627320 | 15 | + | 27869803 | HPAFII | viability after 31 days | TTACTACACGTGGAGAGAGCAGG | CPEB1 | ENSG00000214575 | -0.8105979875572016 | [569] | [257,99,NaN] | -5 | hSpCas9 | negative selection | 10049788 | 82571460 | 82571483 | 15 | - | 28162770 | P31FUJ | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.7156674949455393 | [740] | [1429] | 7 | hSpCas9 | negative selection | 10137347 | 82571413 | 82571436 | 15 | + | 28162770 | P31FUJ | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.5755199956150209 | [212] | [372] | 6 | hSpCas9 | negative selection | 10137348 | 82571460 | 82571483 | 15 | - | 28162770 | TF1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | NaN | [NaN] | [271] | 1 | hSpCas9 | negative selection | 10306713 | 82571413 | 82571436 | 15 | + | 28162770 | TF1 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | NaN | [NaN] | [354] | 1 | hSpCas9 | negative selection | 10306714 | 82571460 | 82571483 | 15 | - | 28162770 | SKM1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.13219683144335126 | [198] | [320] | -1 | hSpCas9 | negative selection | 10476079 | 82571413 | 82571436 | 15 | + | 28162770 | SKM1 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.02367015558670066 | [68] | [123] | 0 | hSpCas9 | negative selection | 10476080 | 82571460 | 82571483 | 15 | - | 28162770 | SKM1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.13219683144335126 | [198] | [320] | -1 | hSpCas9 | negative selection | 10645445 | 82571413 | 82571436 | 15 | + | 28162770 | SKM1 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.02367015558670066 | [68] | [123] | 0 | hSpCas9 | negative selection | 10645446 | 82571460 | 82571483 | 15 | - | 28162770 | PL21 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.24890544148458393 | [668] | [345] | 2 | hSpCas9 | negative selection | 10814811 | 82571413 | 82571436 | 15 | + | 28162770 | PL21 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.13087695205220634 | [255] | [121] | 1 | hSpCas9 | negative selection | 10814812 | 82571460 | 82571483 | 15 | - | 28162770 | P31FUJ | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.7156674949455393 | [740] | [1429] | 7 | hSpCas9 | negative selection | 10984177 | 82571413 | 82571436 | 15 | + | 28162770 | P31FUJ | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.5755199956150209 | [212] | [372] | 6 | hSpCas9 | negative selection | 10984178 | 82571460 | 82571483 | 15 | - | 28162770 | OCIAML5 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.1182927811875003 | [361] | [601] | -1 | hSpCas9 | negative selection | 11153543 | 82571413 | 82571436 | 15 | + | 28162770 | OCIAML5 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.7167762644938822 | [119] | [355] | 6 | hSpCas9 | negative selection | 11153544 | 82571460 | 82571483 | 15 | - | 28162770 | EOL1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.6356706299476849 | [1272] | [1041] | 5 | hSpCas9 | negative selection | 11322909 | 82571413 | 82571436 | 15 | + | 28162770 | EOL1 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.5245777203806326 | [507] | [384] | 5 | hSpCas9 | negative selection | 11322910 | 82571460 | 82571483 | 15 | - | 28162770 | MOLM13 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.8947040485997764 | [975] | [1311] | 6 | hSpCas9 | negative selection | 11492275 | 82571413 | 82571436 | 15 | + | 28162770 | MOLM13 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 1.204854975710785 | [314] | [524] | 8 | hSpCas9 | negative selection | 11492276 | 82571460 | 82571483 | 15 | - | 28162770 | HEL | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.39588667997872884 | [921] | [776] | 3 | hSpCas9 | negative selection | 11661641 | 82571413 | 82571436 | 15 | + | 28162770 | HEL | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.8562531019903519 | [325] | [377] | 7 | hSpCas9 | negative selection | 11661642 | 82571460 | 82571483 | 15 | - | 28162770 | MV411 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.0550506632808998 | [644] | [522] | 0 | hSpCas9 | negative selection | 11831007 | 82571413 | 82571436 | 15 | + | 28162770 | MV411 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.9255094558954128 | [269] | [431] | 8 | hSpCas9 | negative selection | 11831008 | 82571460 | 82571483 | 15 | - | 28162770 | MONOMAC1 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.3309894887087508 | [490] | [707] | 3 | hSpCas9 | negative selection | 12000373 | 82571413 | 82571436 | 15 | + | 28162770 | MONOMAC1 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.5233971882621767 | [162] | [129] | -4 | hSpCas9 | negative selection | 12000374 | 82571460 | 82571483 | 15 | - | 28162770 | OCIAML2 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | 0.47355931178933286 | [111] | [861] | 4 | hSpCas9 | negative selection | 12169739 | 82571413 | 82571436 | 15 | + | 28162770 | OCIAML2 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | 0.3733540188061655 | [49] | [358] | 3 | hSpCas9 | negative selection | 12169740 | 82571460 | 82571483 | 15 | - | 28162770 | OCIAML3 | viability | TCTGCGCAAGAATCTTCCCGTGG | CPEB1 | ENSG00000214575 | -0.06199401955196615 | [221] | [641] | 0 | hSpCas9 | negative selection | 12339105 | 82571413 | 82571436 | 15 | + | 28162770 | OCIAML3 | viability | GACTGAGGGACTGCAGGCCAAGG | CPEB1 | ENSG00000214575 | -0.41856563391428503 | [57] | [130] | -3 | hSpCas9 | negative selection | 12339106 |