Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1399
• Symbol:CRKL
• Description:CRK like proto-oncogene, adaptor protein

DataSource: http://genomecrispr.dkfz.de/#!/results/CRKL

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
20917939	20917962	22	-	26472758	Jiyoye	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	2.2484776354868155	[11]	[42]	9	hSpCas9	negative selection	37111
20918183	20918206	22	-	26472758	Jiyoye	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-1.2773227927661972	[89]	[27]	-7	hSpCas9	negative selection	37112
20918111	20918134	22	-	26472758	Jiyoye	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	-0.2875877141753702	[538]	[332]	-2	hSpCas9	negative selection	37113
20918138	20918161	22	-	26472758	Jiyoye	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.17094103501579494	[191]	[162]	1	hSpCas9	negative selection	37114
20933776	20933799	22	+	26472758	Jiyoye	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.3168430617849656	[345]	[324]	2	hSpCas9	negative selection	37115
20918221	20918244	22	-	26472758	Jiyoye	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.4914442984034773	[132]	[140]	3	hSpCas9	negative selection	37116
20933925	20933948	22	+	26472758	Jiyoye	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	0.8605409994438165	[64]	[88]	6	hSpCas9	negative selection	37117
20934210	20934233	22	-	26472758	Jiyoye	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-0.47352569012178203	[231]	[125]	-3	hSpCas9	negative selection	37118
20917964	20917987	22	-	26472758	Jiyoye	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-0.19321715978488874	[93]	[61]	-1	hSpCas9	negative selection	37119
20918024	20918047	22	-	26472758	Jiyoye	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	1.8222128807847173	[11]	[31]	8	hSpCas9	negative selection	37120
20917939	20917962	22	-	26472758	KBM7	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	-0.7039947701595672	[137,108]	[27,41]	-5	hSpCas9	negative selection	228229
20918183	20918206	22	-	26472758	KBM7	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.41467570591811254	[340,316]	[159,76]	-4	hSpCas9	negative selection	228230
20918111	20918134	22	-	26472758	KBM7	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.38214389906216595	[1341,1290]	[1128,522]	4	hSpCas9	negative selection	228231
20918138	20918161	22	-	26472758	KBM7	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.5051963696411842	[601,515]	[429,319]	5	hSpCas9	negative selection	228232
20933776	20933799	22	+	26472758	KBM7	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.434145895229219	[1518,911]	[789,725]	5	hSpCas9	negative selection	228233
20918221	20918244	22	-	26472758	KBM7	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.5292519599634496	[579,361]	[207,407]	6	hSpCas9	negative selection	228234
20933925	20933948	22	+	26472758	KBM7	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.14681672704305293	[401,371]	[154,172]	-1	hSpCas9	negative selection	228235
20934210	20934233	22	-	26472758	KBM7	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.17653618460035314	[905,908]	[575,402]	1	hSpCas9	negative selection	228236
20917964	20917987	22	-	26472758	KBM7	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-0.12915811655531612	[468,399]	[191,180]	-1	hSpCas9	negative selection	228237
20918024	20918047	22	-	26472758	KBM7	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-0.826169172209584	[136,457]	[99,68]	-6	hSpCas9	negative selection	228238
20917939	20917962	22	-	26472758	Raji	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.3000286133159955	[20]	[5]	3	hSpCas9	negative selection	419347
20918183	20918206	22	-	26472758	Raji	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	0.36014960575356614	[187]	[55]	3	hSpCas9	negative selection	419348
20918111	20918134	22	-	26472758	Raji	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	-0.21454455951376294	[574]	[114]	-2	hSpCas9	negative selection	419349
20918138	20918161	22	-	26472758	Raji	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.5124369460798213	[289]	[95]	5	hSpCas9	negative selection	419350
20933776	20933799	22	+	26472758	Raji	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.7693657379479313	[540]	[213]	7	hSpCas9	negative selection	419351
20918221	20918244	22	-	26472758	Raji	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.7150661125948393	[104]	[39]	6	hSpCas9	negative selection	419352
20933925	20933948	22	+	26472758	Raji	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	0.9941729249256085	[105]	[48]	8	hSpCas9	negative selection	419353
20934210	20934233	22	-	26472758	Raji	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.3944134222763718	[317]	[96]	4	hSpCas9	negative selection	419354
20917964	20917987	22	-	26472758	Raji	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-0.5555814773488297	[246]	[38]	-4	hSpCas9	negative selection	419355
20918024	20918047	22	-	26472758	Raji	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	0.15985095526773518	[80]	[20]	1	hSpCas9	negative selection	419356
20917939	20917962	22	-	26472758	K562	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	-4.376167682785431	[122]	[4]	-9	hSpCas9	negative selection	610465
20918183	20918206	22	-	26472758	K562	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-3.405835233306429	[225]	[17]	-8	hSpCas9	negative selection	610466
20918111	20918134	22	-	26472758	K562	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	-1.4230785308081966	[1168]	[367]	-6	hSpCas9	negative selection	610467
20918138	20918161	22	-	26472758	K562	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	-3.467534978491686	[628]	[47]	-8	hSpCas9	negative selection	610468
20933776	20933799	22	+	26472758	K562	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	-1.4730678585595343	[1127]	[342]	-6	hSpCas9	negative selection	610469
20918221	20918244	22	-	26472758	K562	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	-4.282623797125528	[414]	[17]	-9	hSpCas9	negative selection	610470
20933925	20933948	22	+	26472758	K562	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.7256280502319254	[285]	[145]	-4	hSpCas9	negative selection	610471
20934210	20934233	22	-	26472758	K562	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-1.0026741342983254	[647]	[272]	-5	hSpCas9	negative selection	610472
20917964	20917987	22	-	26472758	K562	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-1.5319980172184833	[345]	[100]	-6	hSpCas9	negative selection	610473
20918024	20918047	22	-	26472758	K562	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-1.5491303948661266	[103]	[29]	-6	hSpCas9	negative selection	610474
20917945	20917968	22	-	26627737	DLD1	viability	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-0.6829249801509416	[151]	[17,33,35]	-6	hSpCas9	negative selection	816848
20917986	20918009	22	-	26627737	DLD1	viability	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.5405383687882026	[547]	[35,66,71]	-8	hSpCas9	negative selection	816849
20933818	20933841	22	-	26627737	DLD1	viability	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.204670530008391	[138]	[6,18,28]	-8	hSpCas9	negative selection	816850
20933948	20933971	22	+	26627737	DLD1	viability	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-1.2546383989776435	[492]	[31,67,89]	-8	hSpCas9	negative selection	816851
20949754	20949777	22	+	26627737	DLD1	viability	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.01232988617676034	[281]	[105,65,88]	0	hSpCas9	negative selection	816852
20949763	20949786	22	+	26627737	DLD1	viability	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.5564726623943008	[1136]	[237,290,203]	-5	hSpCas9	negative selection	816853
20917945	20917968	22	-	26627737	GBM cells	viability after 5 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	0.16194828071947942	[9]	[6,4]	2	hSpCas9	negative selection	899163
20917986	20918009	22	-	26627737	GBM cells	viability after 5 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	0.3952187557864449	[150]	[82,129]	6	hSpCas9	negative selection	899164
20933818	20933841	22	-	26627737	GBM cells	viability after 5 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	0.23594886216325617	[75]	[41,53]	3	hSpCas9	negative selection	899165
20933948	20933971	22	+	26627737	GBM cells	viability after 5 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-0.6811828706636548	[295]	[83,113]	-8	hSpCas9	negative selection	899166
20949754	20949777	22	+	26627737	GBM cells	viability after 5 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.4477366494129081	[205]	[99,61]	-6	hSpCas9	negative selection	899167
20949763	20949786	22	+	26627737	GBM cells	viability after 5 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.42961478182036794	[595]	[451,408]	6	hSpCas9	negative selection	899168
20917945	20917968	22	-	26627737	GBM cells	viability after 13 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	0.3244612288568032	[9]	[8,4]	4	hSpCas9	negative selection	981478
20917986	20918009	22	-	26627737	GBM cells	viability after 13 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	0.04896501071264592	[150]	[81,86]	0	hSpCas9	negative selection	981479
20933818	20933841	22	-	26627737	GBM cells	viability after 13 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	0.16440979819239265	[75]	[59,34]	2	hSpCas9	negative selection	981480
20933948	20933971	22	+	26627737	GBM cells	viability after 13 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-1.1553640370151566	[295]	[70,72]	-8	hSpCas9	negative selection	981481
20949754	20949777	22	+	26627737	GBM cells	viability after 13 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.7197453123219739	[205]	[79,57]	-7	hSpCas9	negative selection	981482
20949763	20949786	22	+	26627737	GBM cells	viability after 13 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.3659729921027024	[595]	[472,370]	5	hSpCas9	negative selection	981483
20917945	20917968	22	-	26627737	GBM cells	viability after 21 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	0.13254129885639454	[9]	[6,4]	1	hSpCas9	negative selection	1063793
20917986	20918009	22	-	26627737	GBM cells	viability after 21 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.3900806876641646	[150]	[71,53]	-4	hSpCas9	negative selection	1063794
20933818	20933841	22	-	26627737	GBM cells	viability after 21 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	0.10587625565252745	[75]	[45,42]	1	hSpCas9	negative selection	1063795
20933948	20933971	22	+	26627737	GBM cells	viability after 21 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-0.25525705524207465	[295]	[140,128]	-2	hSpCas9	negative selection	1063796
20949754	20949777	22	+	26627737	GBM cells	viability after 21 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.9279778444018363	[205]	[62,54]	-7	hSpCas9	negative selection	1063797
20949763	20949786	22	+	26627737	GBM cells	viability after 21 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.5550740834652828	[595]	[481,469]	5	hSpCas9	negative selection	1063798
20917945	20917968	22	-	26627737	RPE1	viability after 9 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-3.06394924358084	[423]	[14,16]	-9	hSpCas9	negative selection	1146108
20917986	20918009	22	-	26627737	RPE1	viability after 9 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.1857233793745658	[546]	[90,54]	-7	hSpCas9	negative selection	1146109
20933818	20933841	22	-	26627737	RPE1	viability after 9 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-0.4783315922059759	[223]	[0,113]	-3	hSpCas9	negative selection	1146110
20933948	20933971	22	+	26627737	RPE1	viability after 9 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-2.194595795638295	[1157]	[21,152]	-9	hSpCas9	negative selection	1146111
20949754	20949777	22	+	26627737	RPE1	viability after 9 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.10879386123677515	[321]	[85,137]	0	hSpCas9	negative selection	1146112
20949763	20949786	22	+	26627737	RPE1	viability after 9 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.5385654196200229	[2498]	[659,381]	-4	hSpCas9	negative selection	1146113
20917945	20917968	22	-	26627737	RPE1	viability after 12 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-3.4219332487269964	[423]	[14,5]	-9	hSpCas9	negative selection	1228423
20917986	20918009	22	-	26627737	RPE1	viability after 12 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-2.2910216741022067	[546]	[47,10]	-9	hSpCas9	negative selection	1228424
20933818	20933841	22	-	26627737	RPE1	viability after 12 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.7276435720450773	[223]	[6,29]	-8	hSpCas9	negative selection	1228425
20933948	20933971	22	+	26627737	RPE1	viability after 12 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-3.460764432501954	[1157]	[19,36]	-9	hSpCas9	negative selection	1228426
20949754	20949777	22	+	26627737	RPE1	viability after 12 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.7851900073780693	[321]	[39,60]	-5	hSpCas9	negative selection	1228427
20949763	20949786	22	+	26627737	RPE1	viability after 12 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-1.4336729422822923	[2498]	[283,210]	-7	hSpCas9	negative selection	1228428
20917945	20917968	22	-	26627737	RPE1	viability after 15 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-3.2738507207340914	[423]	[17,6]	-9	hSpCas9	negative selection	1310738
20917986	20918009	22	-	26627737	RPE1	viability after 15 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.8945246524517565	[546]	[34,47]	-8	hSpCas9	negative selection	1310739
20933818	20933841	22	-	26627737	RPE1	viability after 15 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.6518132170205708	[223]	[38,1]	-7	hSpCas9	negative selection	1310740
20933948	20933971	22	+	26627737	RPE1	viability after 15 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-4.393913261816964	[1157]	[10,19]	-9	hSpCas9	negative selection	1310741
20949754	20949777	22	+	26627737	RPE1	viability after 15 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.5397847387803527	[321]	[81,43]	-3	hSpCas9	negative selection	1310742
20949763	20949786	22	+	26627737	RPE1	viability after 15 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.4957230679329827	[2498]	[734,275]	-3	hSpCas9	negative selection	1310743
20917945	20917968	22	-	26627737	RPE1	viability after 18 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-3.2334838025942236	[423]	[16,6]	-9	hSpCas9	negative selection	1393053
20917986	20918009	22	-	26627737	RPE1	viability after 18 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.2920169012272813	[546]	[53,66]	-7	hSpCas9	negative selection	1393054
20933818	20933841	22	-	26627737	RPE1	viability after 18 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.5923439026567345	[223]	[35,2]	-7	hSpCas9	negative selection	1393055
20933948	20933971	22	+	26627737	RPE1	viability after 18 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-3.8401783484634486	[1157]	[1,42]	-9	hSpCas9	negative selection	1393056
20949754	20949777	22	+	26627737	RPE1	viability after 18 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.3526801477374102	[321]	[54,81]	-2	hSpCas9	negative selection	1393057
20949763	20949786	22	+	26627737	RPE1	viability after 18 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-1.061949566035699	[2498]	[352,290]	-6	hSpCas9	negative selection	1393058
20917945	20917968	22	-	26627737	HeLa	viability after 8 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	0.022175122191250285	[544]	[200,142,360]	0	hSpCas9	negative selection	1475368
20917986	20918009	22	-	26627737	HeLa	viability after 8 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.906347719982957	[302]	[27,77,93]	-7	hSpCas9	negative selection	1475369
20933818	20933841	22	-	26627737	HeLa	viability after 8 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.8457407981066076	[234]	[63,12,16]	-9	hSpCas9	negative selection	1475370
20933948	20933971	22	+	26627737	HeLa	viability after 8 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	0.06893550916701408	[330]	[289,89,106]	0	hSpCas9	negative selection	1475371
20949754	20949777	22	+	26627737	HeLa	viability after 8 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.3873443182889395	[483]	[535,164,188]	3	hSpCas9	negative selection	1475372
20949763	20949786	22	+	26627737	HeLa	viability after 8 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.1388921154730609	[885]	[507,494,297]	1	hSpCas9	negative selection	1475373
20917945	20917968	22	-	26627737	HeLa	viability after 12 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-0.7547863104123215	[544]	[123,134,140]	-6	hSpCas9	negative selection	1557683
20917986	20918009	22	-	26627737	HeLa	viability after 12 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.0990645457423942	[302]	[51,78,41]	-7	hSpCas9	negative selection	1557684
20933818	20933841	22	-	26627737	HeLa	viability after 12 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-0.4142861537570435	[234]	[130,56,33]	-4	hSpCas9	negative selection	1557685
20933948	20933971	22	+	26627737	HeLa	viability after 12 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	0.47861217748245355	[330]	[289,83,211]	4	hSpCas9	negative selection	1557686
20949754	20949777	22	+	26627737	HeLa	viability after 12 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.43042152677136675	[483]	[350,165,304]	3	hSpCas9	negative selection	1557687
20949763	20949786	22	+	26627737	HeLa	viability after 12 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.4641824706316453	[885]	[518,568,420]	4	hSpCas9	negative selection	1557688
20917945	20917968	22	-	26627737	HeLa	viability after 15 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-0.5562177344218764	[544]	[101,34,329]	-5	hSpCas9	negative selection	1639998
20917986	20918009	22	-	26627737	HeLa	viability after 15 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.820125367261163	[302]	[2,118,89]	-6	hSpCas9	negative selection	1639999
20933818	20933841	22	-	26627737	HeLa	viability after 15 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.5511690668753046	[234]	[53,18,23]	-8	hSpCas9	negative selection	1640000
20933948	20933971	22	+	26627737	HeLa	viability after 15 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-0.46786802796860605	[330]	[129,86,72]	-4	hSpCas9	negative selection	1640001
20949754	20949777	22	+	26627737	HeLa	viability after 15 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.7990318296167453	[483]	[35,151,155]	-6	hSpCas9	negative selection	1640002
20949763	20949786	22	+	26627737	HeLa	viability after 15 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.5957212517861801	[885]	[606,475,551]	5	hSpCas9	negative selection	1640003
20917945	20917968	22	-	26627737	HeLa	viability after 18 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-0.5731440969399456	[544]	[64,28,329]	-5	hSpCas9	negative selection	1722313
20917986	20918009	22	-	26627737	HeLa	viability after 18 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.7973850976059922	[302]	[2,99,89]	-6	hSpCas9	negative selection	1722314
20933818	20933841	22	-	26627737	HeLa	viability after 18 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.5245670905956201	[234]	[37,14,23]	-8	hSpCas9	negative selection	1722315
20933948	20933971	22	+	26627737	HeLa	viability after 18 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-0.4307169181881352	[330]	[92,70,72]	-4	hSpCas9	negative selection	1722316
20949754	20949777	22	+	26627737	HeLa	viability after 18 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.7810854200808327	[483]	[25,126,155]	-6	hSpCas9	negative selection	1722317
20949763	20949786	22	+	26627737	HeLa	viability after 18 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.6160023207342022	[885]	[423,391,551]	5	hSpCas9	negative selection	1722318
20917945	20917968	22	-	26627737	HCT116	viability after 6 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-1.6271070021220297	[875]	[12,61]	-7	hSpCas9	negative selection	1804628
20917986	20918009	22	-	26627737	HCT116	viability after 6 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-2.0281285115006145	[346]	[33,1]	-8	hSpCas9	negative selection	1804629
20933818	20933841	22	-	26627737	HCT116	viability after 6 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-3.93065258499956	[96]	[0,0]	-9	hSpCas9	negative selection	1804630
20933948	20933971	22	+	26627737	HCT116	viability after 6 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-3.466068424593701	[594]	[21,0]	-9	hSpCas9	negative selection	1804631
20949754	20949777	22	+	26627737	HCT116	viability after 6 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.10793673618845434	[489]	[133,36]	0	hSpCas9	negative selection	1804632
20949763	20949786	22	+	26627737	HCT116	viability after 6 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.3453653974039317	[2055]	[1118,19]	2	hSpCas9	negative selection	1804633
20917945	20917968	22	-	26627737	HCT116	viability after 8 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-1.3666393146486597	[348]	[85,68,68]	-9	hSpCas9	negative selection	1886943
20917986	20918009	22	-	26627737	HCT116	viability after 8 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.9573043062393445	[135]	[43,42,28]	-8	hSpCas9	negative selection	1886944
20933818	20933841	22	-	26627737	HCT116	viability after 8 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-0.7350003613701765	[130]	[47,22,58]	-7	hSpCas9	negative selection	1886945
20933948	20933971	22	+	26627737	HCT116	viability after 8 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-2.1546638240802274	[539]	[35,102,60]	-9	hSpCas9	negative selection	1886946
20949754	20949777	22	+	26627737	HCT116	viability after 8 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.36664781384937417	[353]	[177,96,178]	-4	hSpCas9	negative selection	1886947
20949763	20949786	22	+	26627737	HCT116	viability after 8 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.41931667090197655	[526]	[431,279,452]	4	hSpCas9	negative selection	1886948
20917945	20917968	22	-	26627737	HCT116	viability after 9 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-3.8665515887440507	[875]	[29,4]	-9	hSpCas9	negative selection	1969258
20917986	20918009	22	-	26627737	HCT116	viability after 9 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.3100177287616726	[346]	[9,58]	-7	hSpCas9	negative selection	1969259
20933818	20933841	22	-	26627737	HCT116	viability after 9 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	2.1083645216257536	[96]	[128,97]	9	hSpCas9	negative selection	1969260
20933948	20933971	22	+	26627737	HCT116	viability after 9 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-1.9212965702836593	[594]	[51,33]	-8	hSpCas9	negative selection	1969261
20949754	20949777	22	+	26627737	HCT116	viability after 9 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.2571659981289328	[489]	[66,226]	2	hSpCas9	negative selection	1969262
20949763	20949786	22	+	26627737	HCT116	viability after 9 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.6240983293720788	[2055]	[587,172]	-4	hSpCas9	negative selection	1969263
20917945	20917968	22	-	26627737	HCT116	viability after 12 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-1.8185473917262862	[348]	[89,24,36]	-9	hSpCas9	negative selection	2051573
20917986	20918009	22	-	26627737	HCT116	viability after 12 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.6859811735370271	[135]	[14,10,40]	-9	hSpCas9	negative selection	2051574
20933818	20933841	22	-	26627737	HCT116	viability after 12 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-0.49137751304490096	[130]	[9,34,104]	-5	hSpCas9	negative selection	2051575
20933948	20933971	22	+	26627737	HCT116	viability after 12 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-1.9692579166840027	[539]	[52,66,98]	-9	hSpCas9	negative selection	2051576
20949754	20949777	22	+	26627737	HCT116	viability after 12 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.05479279584982508	[353]	[150,146,240]	0	hSpCas9	negative selection	2051577
20949763	20949786	22	+	26627737	HCT116	viability after 12 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.3368299937499487	[526]	[386,304,352]	3	hSpCas9	negative selection	2051578
20917945	20917968	22	-	26627737	HCT116	viability after 15 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-2.0362513492032246	[348]	[35,57,50]	-9	hSpCas9	negative selection	2133888
20917986	20918009	22	-	26627737	HCT116	viability after 15 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.4468403528216467	[135]	[35,34,15]	-8	hSpCas9	negative selection	2133889
20933818	20933841	22	-	26627737	HCT116	viability after 15 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.558688302256571	[130]	[6,11,54]	-8	hSpCas9	negative selection	2133890
20933948	20933971	22	+	26627737	HCT116	viability after 15 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-4.010175409557943	[539]	[35,22,0]	-9	hSpCas9	negative selection	2133891
20949754	20949777	22	+	26627737	HCT116	viability after 15 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-1.1069058620372698	[353]	[67,120,90]	-8	hSpCas9	negative selection	2133892
20949763	20949786	22	+	26627737	HCT116	viability after 15 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.07322954968079765	[526]	[303,290,357]	0	hSpCas9	negative selection	2133893
20917945	20917968	22	-	26627737	HCT116	viability after 18 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-1.7631669299880892	[348]	[31,57,58]	-8	hSpCas9	negative selection	2216203
20917986	20918009	22	-	26627737	HCT116	viability after 18 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.9819101297676427	[135]	[33,48,14]	-7	hSpCas9	negative selection	2216204
20933818	20933841	22	-	26627737	HCT116	viability after 18 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-2.499143069847268	[130]	[6,0,26]	-9	hSpCas9	negative selection	2216205
20933948	20933971	22	+	26627737	HCT116	viability after 18 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-4.818394133350127	[539]	[16,3,6]	-9	hSpCas9	negative selection	2216206
20949754	20949777	22	+	26627737	HCT116	viability after 18 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.6006633075085533	[353]	[65,196,67]	-5	hSpCas9	negative selection	2216207
20949763	20949786	22	+	26627737	HCT116	viability after 18 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.17649911573993282	[526]	[351,259,251]	1	hSpCas9	negative selection	2216208
20947932	20947955	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAAGCTGAAG	CRKL	ENSG00000099942	4.479776146187553	[3,10]	[5,71]	9	dCas9-VP64	positive selection	2414928
20947932	20947955	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAAGCTGAAG	CRKL	ENSG00000099942	1.4055177615841226	[19,51]	[4,54]	7	dCas9-VP64	positive selection	2510183
20917969	20917992	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACCGGCCCCATATACCAGGCGG	CRKL	ENSG00000099942	-0.07689498260946534	[4,3]	[2,3]	-1	hSpCas9	positive selection	2981164
20918066	20918089	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGACAGCACATAGTCCCCAGGG	CRKL	ENSG00000099942	0.0603601951997178	[1,2]	[0,2]	1	hSpCas9	positive selection	2981165
20918182	20918205	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCTTGTAAAACTCCAGCAGGG	CRKL	ENSG00000099942	-0.20869343995680228	[3,4]	[2,3]	-3	hSpCas9	positive selection	2981166
20918138	20918161	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	-0.47234460423973157	[2,2]	[2,0]	-6	hSpCas9	positive selection	2981167
20917969	20917992	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACCGGCCCCATATACCAGGCGG	CRKL	ENSG00000099942	-0.8133417127963508	[4,4]	[2,0]	-9	hSpCas9	positive selection	3049022
20918066	20918089	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGACAGCACATAGTCCCCAGGG	CRKL	ENSG00000099942	0.7606776856021904	[1,1]	[0,3]	9	hSpCas9	positive selection	3049023
20918182	20918205	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCTTGTAAAACTCCAGCAGGG	CRKL	ENSG00000099942	-0.2756118010059502	[3,3]	[1,2]	-4	hSpCas9	positive selection	3049024
20918138	20918161	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.3995738708500858	[2,2]	[4,0]	7	hSpCas9	positive selection	3049025
20949828	20949851		-	24336571	A375	resistance to PLX after 7 days	AGCAATCACTCGTTTTCATCTGG	CRKL	ENSG00000099942	-0.3097047662454682	[8,10]	[6,8]	-8	hSpCas9	positive selection	3107442
20933870	20933893		-	24336571	A375	resistance to PLX after 7 days	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.3318911348105851	[2,2]	[1,1]	-8	hSpCas9	positive selection	3107443
20949752	20949775		-	24336571	A375	resistance to PLX after 7 days	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.14032690437006023	[8,8]	[7,7]	-4	hSpCas9	positive selection	3107444
20934074	20934097		-	24336571	A375	resistance to PLX after 7 days	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.24398914839052321	[3,3]	[2,3]	-7	hSpCas9	positive selection	3107445
20949828	20949851		-	24336571	A375	resistance to PLX after 14 days	AGCAATCACTCGTTTTCATCTGG	CRKL	ENSG00000099942	-0.8264577185832809	[9,10]	[1,1]	-8	hSpCas9	positive selection	3165235
20933870	20933893		-	24336571	A375	resistance to PLX after 14 days	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.18477377967565833	[3,2]	[1,1]	2	hSpCas9	positive selection	3165236
20949752	20949775		-	24336571	A375	resistance to PLX after 14 days	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.46023829037777414	[7,9]	[2,1]	-5	hSpCas9	positive selection	3165237
20934074	20934097		-	24336571	A375	resistance to PLX after 14 days	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	1.0478556910299828	[2,1]	[2,1]	8	hSpCas9	positive selection	3165238
20949828	20949851		-	24336571	A375	viability after 7 days	AGCAATCACTCGTTTTCATCTGG	CRKL	ENSG00000099942	0.23737607288731805	[8]	[8,10]	3	hSpCas9	negative selection	3223028
20933870	20933893		-	24336571	A375	viability after 7 days	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-1.4074816843363118	[9]	[2,2]	-9	hSpCas9	negative selection	3223029
20949752	20949775		-	24336571	A375	viability after 7 days	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.9623375082591633	[17]	[8,8]	-8	hSpCas9	negative selection	3223030
20934074	20934097		-	24336571	A375	viability after 7 days	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.20527482820916565	[4]	[3,3]	-3	hSpCas9	negative selection	3223031
20949828	20949851		-	24336571	A375	viability after 14 days	AGCAATCACTCGTTTTCATCTGG	CRKL	ENSG00000099942	0.3072214776444238	[8]	[9,10]	4	hSpCas9	negative selection	3280821
20933870	20933893		-	24336571	A375	viability after 14 days	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-1.3409477548696884	[9]	[3,2]	-9	hSpCas9	negative selection	3280822
20949752	20949775		-	24336571	A375	viability after 14 days	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.8802593552296505	[17]	[7,9]	-8	hSpCas9	negative selection	3280823
20934074	20934097		-	24336571	A375	viability after 14 days	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.9317601406331673	[4]	[2,1]	-8	hSpCas9	negative selection	3280824
20918134	20918157	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	4.9372852261027385	[3,5]	[0,0]	9	hSpCas9	positive selection	3344575
20917979	20918002	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	3.0847843127852137	[22,12]	[0,0]	8	hSpCas9	positive selection	3344576
20933870	20933893	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.3160487110593353	[184,195]	[0,0]	-2	hSpCas9	positive selection	3344577
20934074	20934097	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	1.7337642553888224	[45,45]	[0,0]	7	hSpCas9	positive selection	3363798
20949752	20949775	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.8771001087750909	[280,280]	[0,0]	-6	hSpCas9	positive selection	3363799
20949715	20949738	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3363800
20917969	20917992	22	-	26780180	HT29	viability (Avana library 4 designs)	CACCGGCCCCATATACCAGGCGG	CRKL	ENSG00000099942	5.84648812232701	[]	[]	9	hSpCas9	negative selection	3417642
20918066	20918089	22	-	26780180	HT29	viability (Avana library 4 designs)	CCGACAGCACATAGTCCCCAGGG	CRKL	ENSG00000099942	4.22698850477326	[]	[]	9	hSpCas9	negative selection	3417643
20918182	20918205	22	-	26780180	HT29	viability (Avana library 4 designs)	GATCTTGTAAAACTCCAGCAGGG	CRKL	ENSG00000099942	5.7817158537719	[]	[]	9	hSpCas9	negative selection	3417644
20918138	20918161	22	-	26780180	HT29	viability (Avana library 4 designs)	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	4.73215748050765	[]	[]	9	hSpCas9	negative selection	3417645
20918138	20918161	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	-9.20257653932826	[]	[]	-7	hSpCas9	negative selection	3495746
20918066	20918089	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGACAGCACATAGTCCCCAGGG	CRKL	ENSG00000099942	-6.94734833984079	[]	[]	-6	hSpCas9	negative selection	3495747
20917969	20917992	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACCGGCCCCATATACCAGGCGG	CRKL	ENSG00000099942	-10.6132994524095	[]	[]	-8	hSpCas9	negative selection	3495748
20918182	20918205	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCTTGTAAAACTCCAGCAGGG	CRKL	ENSG00000099942	-14.552743244104	[]	[]	-9	hSpCas9	negative selection	3495749
20918051	20918074	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGATTCTTCCACCTGCCCTGGGG	CRKL	ENSG00000099942	-6.10463930370475	[]	[]	-6	hSpCas9	negative selection	3495750
20918141	20918164	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGTCCCCGATCTTAAAACGG	CRKL	ENSG00000099942	0.835378136381077	[]	[]	1	hSpCas9	negative selection	3495751
20918138	20918161	22	-	26780180	A375	viability (Avana lentiGuide)	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	19.9277745838722	[]	[]	8	hSpCas9	negative selection	3604405
20918066	20918089	22	-	26780180	A375	viability (Avana lentiGuide)	CCGACAGCACATAGTCCCCAGGG	CRKL	ENSG00000099942	11.8817177397657	[]	[]	7	hSpCas9	negative selection	3604406
20917969	20917992	22	-	26780180	A375	viability (Avana lentiGuide)	CACCGGCCCCATATACCAGGCGG	CRKL	ENSG00000099942	17.4686864178633	[]	[]	8	hSpCas9	negative selection	3604407
20918182	20918205	22	-	26780180	A375	viability (Avana lentiGuide)	GATCTTGTAAAACTCCAGCAGGG	CRKL	ENSG00000099942	13.055506885427	[]	[]	7	hSpCas9	negative selection	3604408
20918051	20918074	22	+	26780180	A375	viability (Avana lentiGuide)	CGATTCTTCCACCTGCCCTGGGG	CRKL	ENSG00000099942	14.4172287883635	[]	[]	8	hSpCas9	negative selection	3604409
20918141	20918164	22	-	26780180	A375	viability (Avana lentiGuide)	CCTGGTCCCCGATCTTAAAACGG	CRKL	ENSG00000099942	-4.3539362433009	[]	[]	-7	hSpCas9	negative selection	3604410
20918138	20918161	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	-1.0732890741774495	[4]	[1,1]	-9	hSpCas9	positive selection	3713064
20918066	20918089	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGACAGCACATAGTCCCCAGGG	CRKL	ENSG00000099942	-0.896939556249048	[3]	[1,1]	-8	hSpCas9	positive selection	3713065
20917969	20917992	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACCGGCCCCATATACCAGGCGG	CRKL	ENSG00000099942	-1.3189099611538295	[5]	[1,1]	-9	hSpCas9	positive selection	3713066
20918182	20918205	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCTTGTAAAACTCCAGCAGGG	CRKL	ENSG00000099942	-0.8347513025401596	[7]	[3,3]	-8	hSpCas9	positive selection	3713067
20918051	20918074	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGATTCTTCCACCTGCCCTGGGG	CRKL	ENSG00000099942	-1.0643628050349203	[4]	[2,0]	-9	hSpCas9	positive selection	3713068
20918141	20918164	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGTCCCCGATCTTAAAACGG	CRKL	ENSG00000099942	0.020411322799237602	[5]	[5,5]	0	hSpCas9	positive selection	3713069
20918138	20918161	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	-1.019626116157016	[4]	[0,2]	-8	hSpCas9	positive selection	3821671
20918066	20918089	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGACAGCACATAGTCCCCAGGG	CRKL	ENSG00000099942	-1.3372132270930652	[4]	[1,0]	-9	hSpCas9	positive selection	3821672
20917969	20917992	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACCGGCCCCATATACCAGGCGG	CRKL	ENSG00000099942	-0.5781970123438366	[6]	[3,2]	-6	hSpCas9	positive selection	3821673
20918182	20918205	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCTTGTAAAACTCCAGCAGGG	CRKL	ENSG00000099942	-0.36847266631840686	[6]	[3,4]	-5	hSpCas9	positive selection	3821674
20918051	20918074	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGATTCTTCCACCTGCCCTGGGG	CRKL	ENSG00000099942	-1.1238795150459033	[5]	[0,2]	-8	hSpCas9	positive selection	3821675
20918141	20918164	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGTCCCCGATCTTAAAACGG	CRKL	ENSG00000099942	0.2450030614216154	[6]	[6,5]	6	hSpCas9	positive selection	3821676
20933870	20933893	22	-	26780180	A375	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	2.19472599337956	[]	[]	9	hSpCas9	negative selection	3929695
20918134	20918157	22	-	26780180	A375	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.260843435323107	[]	[]	0	hSpCas9	negative selection	3929696
20949752	20949775	22	-	26780180	A375	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	1.43015152548361	[]	[]	8	hSpCas9	negative selection	3929697
20934074	20934097	22	-	26780180	A375	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	1.14227634471169	[]	[]	6	hSpCas9	negative selection	3929698
20949715	20949738	22	+	26780180	A375	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	1.4054433969013	[]	[]	7	hSpCas9	negative selection	3929699
20917979	20918002	22	+	26780180	A375	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.807911791599106	[]	[]	3	hSpCas9	negative selection	3929700
20933870	20933893	22	-	26780180	HT29	viability (GeCKOv2 library)	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	3.30476961708354	[]	[]	9	hSpCas9	negative selection	4037661
20918134	20918157	22	-	26780180	HT29	viability (GeCKOv2 library)	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.406320985853348	[]	[]	1	hSpCas9	negative selection	4037662
20949752	20949775	22	-	26780180	HT29	viability (GeCKOv2 library)	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	2.51071211079039	[]	[]	9	hSpCas9	negative selection	4037663
20934074	20934097	22	-	26780180	HT29	viability (GeCKOv2 library)	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	1.31431301900921	[]	[]	6	hSpCas9	negative selection	4037664
20949715	20949738	22	+	26780180	HT29	viability (GeCKOv2 library)	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	2.4294415129834	[]	[]	9	hSpCas9	negative selection	4037665
20917979	20918002	22	+	26780180	HT29	viability (GeCKOv2 library)	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	1.62377485622029	[]	[]	8	hSpCas9	negative selection	4037666
20949828	20949851	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAATCACTCGTTTTCATCTGG	CRKL	ENSG00000099942	-0.3350814201159786	[2]	[1,0]	-7	hSpCas9	positive selection	4129705
20933870	20933893	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.19851424292296427	[1]	[0,0]	-5	hSpCas9	positive selection	4129706
20949752	20949775	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.3162024782473524	[2]	[3,1]	7	hSpCas9	positive selection	4129707
20934074	20934097	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.15274190898922657	[1]	[0,0]	-4	hSpCas9	positive selection	4129708
20949828	20949851	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAATCACTCGTTTTCATCTGG	CRKL	ENSG00000099942	0.09580133596837007	[2]	[0,0,4,0]	0	hSpCas9	positive selection	4193727
20933870	20933893	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.10693217540980293	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4193728
20949752	20949775	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.2895197079886639	[3]	[1,0,0,0]	-4	hSpCas9	positive selection	4193729
20934074	20934097	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.41133614019691467	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4193730
20918134	20918157	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.1294777403387959	[0]	[0,0]	2	hSpCas9	positive selection	4264879
20917979	20918002	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.537754701195347	[1]	[0,0]	-8	hSpCas9	positive selection	4264880
20933870	20933893	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.07539621893371246	[3]	[2,2]	-1	hSpCas9	positive selection	4264881
20934074	20934097	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.6102263085563683	[1]	[0,0]	-8	hSpCas9	positive selection	4329149
20949752	20949775	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.24473475670018577	[3]	[2,2]	-5	hSpCas9	positive selection	4329150
20949715	20949738	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.848492724417422	[2]	[0,0]	-9	hSpCas9	positive selection	4329151
20918042	20918064	22	-	27760321	OCIAML3	viability	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-0.6538604786606323	[468,391]	[180,254]	-6	hSpCas9	negative selection	4391788
20918134	20918156	22	-	27760321	OCIAML3	viability	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.23461245861146818	[5,6]	[2,9]	2	hSpCas9	negative selection	4391789
20918193	20918215	22	+	27760321	OCIAML3	viability	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-0.3428914975305295	[74,58]	[14,74]	-4	hSpCas9	negative selection	4391790
20918235	20918257	22	-	27760321	OCIAML3	viability	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	0.23034245251995844	[1031,1191]	[891,1208]	2	hSpCas9	negative selection	4391791
20933778	20933800	22	+	27760321	OCIAML3	viability	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	0.5563033791462889	[422,388]	[399,553]	6	hSpCas9	negative selection	4391792
20918042	20918064	22	-	27760321	OCIAML2	viability	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	0.30256176428011006	[468,391]	[397,466]	4	hSpCas9	negative selection	4475251
20918134	20918156	22	-	27760321	OCIAML2	viability	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.5629145866050997	[5,6]	[9,4]	7	hSpCas9	negative selection	4475252
20918193	20918215	22	+	27760321	OCIAML2	viability	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	0.5526006644095367	[74,58]	[81,74]	7	hSpCas9	negative selection	4475253
20918235	20918257	22	-	27760321	OCIAML2	viability	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-0.020994625940083722	[1031,1191]	[706,1141]	0	hSpCas9	negative selection	4475254
20933778	20933800	22	+	27760321	OCIAML2	viability	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-0.11632347476877467	[422,388]	[226,402]	-1	hSpCas9	negative selection	4475255
20918042	20918064	22	-	27760321	MV411	viability	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	0.023529165272260753	[468,391]	[271,310]	0	hSpCas9	negative selection	4558714
20918134	20918156	22	-	27760321	MV411	viability	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.9776917938811396	[5,6]	[0,3]	-6	hSpCas9	negative selection	4558715
20918193	20918215	22	+	27760321	MV411	viability	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-1.4394393502004466	[74,58]	[10,23]	-7	hSpCas9	negative selection	4558716
20918235	20918257	22	-	27760321	MV411	viability	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-0.7410807661054711	[1031,1191]	[281,684]	-5	hSpCas9	negative selection	4558717
20933778	20933800	22	+	27760321	MV411	viability	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	0.5044191844035746	[422,388]	[138,741]	3	hSpCas9	negative selection	4558718
20918042	20918064	22	-	27760321	HL60	viability	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-0.6254347653304552	[468,391]	[194,260]	-6	hSpCas9	negative selection	4642177
20918134	20918156	22	-	27760321	HL60	viability	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.1346907861611797	[5,6]	[0,8]	-1	hSpCas9	negative selection	4642178
20918193	20918215	22	+	27760321	HL60	viability	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	1.4121446452590498	[74,58]	[134,154]	9	hSpCas9	negative selection	4642179
20918235	20918257	22	-	27760321	HL60	viability	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	0.1590628671647527	[1031,1191]	[826,1231]	2	hSpCas9	negative selection	4642180
20933778	20933800	22	+	27760321	HL60	viability	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	0.6662319750184924	[422,388]	[483,570]	7	hSpCas9	negative selection	4642181
20918042	20918064	22	-	27760321	HT1080	viability	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-4.284190111259192	[391,305]	[9,3]	-8	hSpCas9	negative selection	4725640
20918134	20918156	22	-	27760321	HT1080	viability	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-1.3810091929335382	[6,5]	[0,0]	-5	hSpCas9	negative selection	4725641
20918193	20918215	22	+	27760321	HT1080	viability	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-4.386336599442745	[58,45]	[0,0]	-8	hSpCas9	negative selection	4725642
20918235	20918257	22	-	27760321	HT1080	viability	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-3.933890719601786	[1191,929]	[51,0]	-8	hSpCas9	negative selection	4725643
20933778	20933800	22	+	27760321	HT1080	viability	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-7.109011971623587	[388,303]	[0,0]	-9	hSpCas9	negative selection	4725644
20918042	20918064	22	-	27760321	HT29	viability after 7 days	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-0.2796993278079906	[391,305]	[332,490,281]	-4	hSpCas9	negative selection	4809103
20918134	20918156	22	-	27760321	HT29	viability after 7 days	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.5729876313118512	[6,5]	[11,4,0]	-7	hSpCas9	negative selection	4809104
20918193	20918215	22	+	27760321	HT29	viability after 7 days	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-1.236316570797098	[58,45]	[11,25,44]	-9	hSpCas9	negative selection	4809105
20918235	20918257	22	-	27760321	HT29	viability after 7 days	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-1.52279215946031	[1191,929]	[626,336,480]	-9	hSpCas9	negative selection	4809106
20933778	20933800	22	+	27760321	HT29	viability after 7 days	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-0.8234242060414789	[388,303]	[182,273,286]	-8	hSpCas9	negative selection	4809107
20918042	20918064	22	-	27760321	HT29	viability after 25 days	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-3.0626883263128692	[391,305]	[59,54,24]	-8	hSpCas9	negative selection	4892566
20918134	20918156	22	-	27760321	HT29	viability after 25 days	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.5936360271824315	[6,5]	[21,0,9]	6	hSpCas9	negative selection	4892567
20918193	20918215	22	+	27760321	HT29	viability after 25 days	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-5.906018864289269	[58,45]	[0,0,0]	-9	hSpCas9	negative selection	4892568
20918235	20918257	22	-	27760321	HT29	viability after 25 days	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-5.525852298065254	[1191,929]	[38,30,5]	-9	hSpCas9	negative selection	4892569
20933778	20933800	22	+	27760321	HT29	viability after 25 days	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-4.131178806628384	[388,303]	[0,37,30]	-9	hSpCas9	negative selection	4892570
20918042	20918064	22	-	27760321	HT29	viability after 22 days	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-3.2820151532278743	[391,305]	[19,64,39]	-9	hSpCas9	negative selection	4976029
20918134	20918156	22	-	27760321	HT29	viability after 22 days	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	1.999162739825859	[6,5]	[0,0,89]	9	hSpCas9	negative selection	4976030
20918193	20918215	22	+	27760321	HT29	viability after 22 days	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-0.9093243699300699	[58,45]	[92,0,0]	-6	hSpCas9	negative selection	4976031
20918235	20918257	22	-	27760321	HT29	viability after 22 days	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-3.4706075801753564	[1191,929]	[130,128,70]	-9	hSpCas9	negative selection	4976032
20933778	20933800	22	+	27760321	HT29	viability after 22 days	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-5.121146820768776	[388,303]	[0,2,30]	-9	hSpCas9	negative selection	4976033
20918042	20918064	22	-	27760321	HT29	viability after 19 days	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-2.773451714066097	[391,305]	[42,85,44]	-8	hSpCas9	negative selection	5059492
20918134	20918156	22	-	27760321	HT29	viability after 19 days	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	2.287901849814476	[6,5]	[0,19,82]	9	hSpCas9	negative selection	5059493
20918193	20918215	22	+	27760321	HT29	viability after 19 days	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-4.969823606742757	[58,45]	[3,0,0]	-9	hSpCas9	negative selection	5059494
20918235	20918257	22	-	27760321	HT29	viability after 19 days	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-4.368544963025124	[1191,929]	[38,99,35]	-9	hSpCas9	negative selection	5059495
20933778	20933800	22	+	27760321	HT29	viability after 19 days	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-5.264326331859565	[388,303]	[11,5,12]	-9	hSpCas9	negative selection	5059496
20918042	20918064	22	-	27760321	HT29	viability after 16 days	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-1.69461408850111	[391,305]	[81,243,28]	-8	hSpCas9	negative selection	5142955
20918134	20918156	22	-	27760321	HT29	viability after 16 days	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-1.8476459384068793	[6,5]	[0,1,2]	-8	hSpCas9	negative selection	5142956
20918193	20918215	22	+	27760321	HT29	viability after 16 days	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-1.7320181099123353	[58,45]	[54,0,0]	-8	hSpCas9	negative selection	5142957
20918235	20918257	22	-	27760321	HT29	viability after 16 days	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-3.2345026511312147	[1191,929]	[256,37,97]	-9	hSpCas9	negative selection	5142958
20933778	20933800	22	+	27760321	HT29	viability after 16 days	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-2.3363066639586574	[388,303]	[122,63,47]	-8	hSpCas9	negative selection	5142959
20918042	20918064	22	-	27760321	HT29	viability after 13 days	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-1.7248224595827093	[391,305]	[169,34,159]	-8	hSpCas9	negative selection	5226418
20918134	20918156	22	-	27760321	HT29	viability after 13 days	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.05769666770895654	[6,5]	[2,0,18]	0	hSpCas9	negative selection	5226419
20918193	20918215	22	+	27760321	HT29	viability after 13 days	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-3.1976533385662087	[58,45]	[12,1,4]	-9	hSpCas9	negative selection	5226420
20918235	20918257	22	-	27760321	HT29	viability after 13 days	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-3.424422813828887	[1191,929]	[91,154,97]	-9	hSpCas9	negative selection	5226421
20933778	20933800	22	+	27760321	HT29	viability after 13 days	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-1.7112474910630988	[388,303]	[185,90,92]	-8	hSpCas9	negative selection	5226422
20918042	20918064	22	-	27760321	HT29	viability after 10 days	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	-0.7417015451824096	[391,305]	[230,238,309]	-7	hSpCas9	negative selection	5309881
20918134	20918156	22	-	27760321	HT29	viability after 10 days	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.9039546503691938	[6,5]	[7,0,3]	-7	hSpCas9	negative selection	5309882
20918193	20918215	22	+	27760321	HT29	viability after 10 days	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	-2.4074661528728276	[58,45]	[34,0,0]	-9	hSpCas9	negative selection	5309883
20918235	20918257	22	-	27760321	HT29	viability after 10 days	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-2.341346456074292	[1191,929]	[235,329,220]	-9	hSpCas9	negative selection	5309884
20933778	20933800	22	+	27760321	HT29	viability after 10 days	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-1.3767779466513392	[388,303]	[136,203,159]	-8	hSpCas9	negative selection	5309885
20918042	20918064	22	-	27760321	MOLM13	viability	GGTGGAAGAATCGCGGACGAGG	CRKL	ENSG00000099942	0.35040686515240554	[468,391]	[228,375]	2	hSpCas9	negative selection	5393344
20918134	20918156	22	-	27760321	MOLM13	viability	CCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.3688641239362065	[5,6]	[0,7]	2	hSpCas9	negative selection	5393345
20918193	20918215	22	+	27760321	MOLM13	viability	TTTTACAAGATCCACTACCTGG	CRKL	ENSG00000099942	0.8695202871383192	[74,58]	[19,109]	6	hSpCas9	negative selection	5393346
20918235	20918257	22	-	27760321	MOLM13	viability	CTCTCGCGTACCTGGGCGCAGG	CRKL	ENSG00000099942	-0.7880696468566324	[1031,1191]	[202,505]	-5	hSpCas9	negative selection	5393347
20933778	20933800	22	+	27760321	MOLM13	viability	GGTATCCAAGCCCACCAATGGG	CRKL	ENSG00000099942	-0.01917501193897872	[422,388]	[77,351]	0	hSpCas9	negative selection	5393348
20917475	20917498	22	+	27661255	K562	viability	GTGGCTATTGGGAACAAGCTGGG	CRKL	ENSG00000099942	0.43273637508229856	[616,746]	[829,649]	9	dCas9-KRAB	negative selection	5472759
20917492	20917515	22	+	27661255	K562	viability	GCTGGGCAAAAGCACCCCGGAGG	CRKL	ENSG00000099942	0.22226013324881277	[944,1131]	[1145,809]	7	dCas9-KRAB	negative selection	5472760
20917702	20917725	22	-	27661255	K562	viability	GAGAGCCGCCCGGGAATGCACGG	CRKL	ENSG00000099942	0.0178744415259513	[1677,1727]	[1476,1290]	0	dCas9-KRAB	negative selection	5472761
20917899	20917922	22	-	27661255	K562	viability	GGACTCTGCGGCGGTAGGGGCGG	CRKL	ENSG00000099942	0.1613576066974216	[667,904]	[694,701]	5	dCas9-KRAB	negative selection	5472762
20918134	20918157	22	-	27260156	BXPC3	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.28554097562242653	[17]	[8,20,36,26]	6	hSpCas9	negative selection	5537339
20917979	20918002	22	+	27260156	BXPC3	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.05830368724985879	[121]	[94,119,129,150]	-1	hSpCas9	negative selection	5537340
20933870	20933893	22	-	27260156	BXPC3	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.10275986633702544	[689]	[753,520,676,738]	-2	hSpCas9	negative selection	5537341
20934074	20934097	22	-	27260156	BXPC3	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.84805713405866	[189]	[84,66,113,189]	-9	hSpCas9	negative selection	5601609
20949752	20949775	22	-	27260156	BXPC3	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.20465055772792773	[864]	[549,713,895,1036]	-5	hSpCas9	negative selection	5601610
20949715	20949738	22	+	27260156	BXPC3	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.9012730166174359	[276]	[131,147,143,203]	-9	hSpCas9	negative selection	5601611
20918134	20918157	22	-	27260156	A673	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.8540058102562846	[17]	[34,23,56,39]	9	hSpCas9	negative selection	5658590
20917979	20918002	22	+	27260156	A673	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.16299975689815538	[121]	[170,113,131,109]	-4	hSpCas9	negative selection	5658591
20933870	20933893	22	-	27260156	A673	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.06350255280535755	[689]	[849,852,900,854]	1	hSpCas9	negative selection	5658592
20934074	20934097	22	-	27260156	A673	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.3637782942710568	[189]	[86,86,94,84]	-9	hSpCas9	negative selection	5722860
20949752	20949775	22	-	27260156	A673	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.1651209170041471	[864]	[1100,1148,1195,1204]	4	hSpCas9	negative selection	5722861
20949715	20949738	22	+	27260156	A673	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.31650354016982774	[276]	[274,262,246,284]	-7	hSpCas9	negative selection	5722862
20918134	20918157	22	-	27260156	A375	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.7107308761017141	[17]	[0,18,14,92]	9	hSpCas9	negative selection	5779841
20917979	20918002	22	+	27260156	A375	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.38090010592754764	[121]	[118,122,103,94]	-5	hSpCas9	negative selection	5779842
20933870	20933893	22	-	27260156	A375	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.0991767276400749	[689]	[799,968,970,738]	1	hSpCas9	negative selection	5779843
20934074	20934097	22	-	27260156	A375	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.3605622220737175	[189]	[139,93,55,59]	-9	hSpCas9	negative selection	5844111
20949752	20949775	22	-	27260156	A375	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.35255664720458413	[864]	[772,1041,860,549]	-5	hSpCas9	negative selection	5844112
20949715	20949738	22	+	27260156	A375	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.3465022203282002	[276]	[191,301,246,278]	-5	hSpCas9	negative selection	5844113
20918134	20918157	22	-	27260156	COLO741	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.1323053582554623	[17]	[32,28,14]	3	hSpCas9	negative selection	5901092
20917979	20918002	22	+	27260156	COLO741	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.04221682713191677	[121]	[182,129,143]	-1	hSpCas9	negative selection	5901093
20933870	20933893	22	-	27260156	COLO741	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.13543704497226283	[689]	[874,705,828]	-3	hSpCas9	negative selection	5901094
20934074	20934097	22	-	27260156	COLO741	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.9525612175509042	[189]	[195,103,84]	-9	hSpCas9	negative selection	5965362
20949752	20949775	22	-	27260156	COLO741	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.08015358753119639	[864]	[1125,1069,951]	-2	hSpCas9	negative selection	5965363
20949715	20949738	22	+	27260156	COLO741	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.27730254954264066	[276]	[386,213,282]	-5	hSpCas9	negative selection	5965364
20918134	20918157	22	-	27260156	CAL120	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-2.406295444429886	[17]	[5,5,0]	-9	hSpCas9	negative selection	6022343
20917979	20918002	22	+	27260156	CAL120	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.20738843417234065	[121]	[297,168,78]	3	hSpCas9	negative selection	6022344
20933870	20933893	22	-	27260156	CAL120	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.021530477123064662	[689]	[742,649,1195]	0	hSpCas9	negative selection	6022345
20934074	20934097	22	-	27260156	CAL120	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.4392048168121101	[189]	[177,192,152]	-6	hSpCas9	negative selection	6086613
20949752	20949775	22	-	27260156	CAL120	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.5361830016958921	[864]	[975,728,559]	-6	hSpCas9	negative selection	6086614
20949715	20949738	22	+	27260156	CAL120	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.8926551118383679	[276]	[235,171,156]	-8	hSpCas9	negative selection	6086615
20918134	20918157	22	-	27260156	CADOES1	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	1.1177720752441407	[17]	[58,23,31,29]	9	hSpCas9	negative selection	6143594
20917979	20918002	22	+	27260156	CADOES1	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.571659597956532	[121]	[213,156,170,130]	8	hSpCas9	negative selection	6143595
20933870	20933893	22	-	27260156	CADOES1	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.42309849754777207	[689]	[865,725,949,900]	7	hSpCas9	negative selection	6143596
20934074	20934097	22	-	27260156	CADOES1	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.8079468793692479	[189]	[105,67,119,109]	-8	hSpCas9	negative selection	6207864
20949752	20949775	22	-	27260156	CADOES1	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.4139794458645013	[864]	[1293,1134,942,908]	7	hSpCas9	negative selection	6207865
20949715	20949738	22	+	27260156	CADOES1	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.1901409033841167	[276]	[262,155,232,251]	-3	hSpCas9	negative selection	6207866
20918134	20918157	22	-	27260156	EWS502	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	1.3520309481305794	[17]	[64,61,55,5]	9	hSpCas9	negative selection	6264845
20917979	20918002	22	+	27260156	EWS502	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.272796283972943	[121]	[86,115,129,95]	-5	hSpCas9	negative selection	6264846
20933870	20933893	22	-	27260156	EWS502	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.13800800673177327	[689]	[730,480,762,680]	-2	hSpCas9	negative selection	6264847
20934074	20934097	22	-	27260156	EWS502	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.0274850755332285	[189]	[95,117,77,101]	-9	hSpCas9	negative selection	6329115
20949752	20949775	22	-	27260156	EWS502	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.12403482965937951	[864]	[725,1052,815,763]	-2	hSpCas9	negative selection	6329116
20949715	20949738	22	+	27260156	EWS502	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.3240847775489113	[276]	[191,303,263,174]	-5	hSpCas9	negative selection	6329117
20918134	20918157	22	-	27260156	EW8	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.8714514858287079	[17]	[19,43,20,21]	9	hSpCas9	negative selection	6386096
20917979	20918002	22	+	27260156	EW8	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.027306139397866858	[121]	[167,83,95,62]	0	hSpCas9	negative selection	6386097
20933870	20933893	22	-	27260156	EW8	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.4750584554359577	[689]	[682,714,810,880]	8	hSpCas9	negative selection	6386098
20934074	20934097	22	-	27260156	EW8	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.2173681729156294	[189]	[43,80,55,82]	-9	hSpCas9	negative selection	6450366
20949752	20949775	22	-	27260156	EW8	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.2947933518273268	[864]	[1011,939,661,873]	5	hSpCas9	negative selection	6450367
20949715	20949738	22	+	27260156	EW8	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	0.13052016647525033	[276]	[349,205,195,249]	2	hSpCas9	negative selection	6450368
20918134	20918157	22	-	27260156	CORL105	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.20592209309719234	[17]	[29,17,20,27]	4	hSpCas9	negative selection	6507347
20917979	20918002	22	+	27260156	CORL105	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.18926696579077218	[121]	[116,86,210,99]	-4	hSpCas9	negative selection	6507348
20933870	20933893	22	-	27260156	CORL105	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.09527547150589977	[689]	[878,768,878,928]	1	hSpCas9	negative selection	6507349
20934074	20934097	22	-	27260156	CORL105	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.2684808583668885	[189]	[158,287,165,119]	-5	hSpCas9	negative selection	6571617
20949752	20949775	22	-	27260156	CORL105	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.10228575354868563	[864]	[879,876,1120,921]	-2	hSpCas9	negative selection	6571618
20949715	20949738	22	+	27260156	CORL105	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.6277897630424114	[276]	[261,209,219,150]	-8	hSpCas9	negative selection	6571619
20918134	20918157	22	-	27260156	HS294T	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.28900172486632414	[17]	[0,3,8,9]	-4	hSpCas9	negative selection	6628598
20917979	20918002	22	+	27260156	HS294T	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-1.0547282975425212	[121]	[20,16,25,27]	-9	hSpCas9	negative selection	6628599
20933870	20933893	22	-	27260156	HS294T	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.14817282549824806	[689]	[261,399,219,299]	2	hSpCas9	negative selection	6628600
20934074	20934097	22	-	27260156	HS294T	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.9271194102363642	[189]	[14,65,34,39]	-8	hSpCas9	negative selection	6692868
20949752	20949775	22	-	27260156	HS294T	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.6931807974313434	[864]	[162,197,224,252]	-7	hSpCas9	negative selection	6692869
20949715	20949738	22	+	27260156	HS294T	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-1.0752614682192072	[276]	[36,36,49,86]	-9	hSpCas9	negative selection	6692870
20918134	20918157	22	-	27260156	HCC44	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.376533384773011	[17]	[53,4,50,5]	6	hSpCas9	negative selection	6749849
20917979	20918002	22	+	27260156	HCC44	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.30719326565995564	[121]	[171,63,123,99]	-5	hSpCas9	negative selection	6749850
20933870	20933893	22	-	27260156	HCC44	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.08989409663716003	[689]	[680,700,962,624]	-1	hSpCas9	negative selection	6749851
20934074	20934097	22	-	27260156	HCC44	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.7328985405576809	[189]	[58,66,88,46]	-9	hSpCas9	negative selection	6814119
20949752	20949775	22	-	27260156	HCC44	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.4929782557125159	[864]	[573,777,661,730]	-6	hSpCas9	negative selection	6814120
20949715	20949738	22	+	27260156	HCC44	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.654908051247685	[276]	[199,128,234,244]	-7	hSpCas9	negative selection	6814121
20918134	20918157	22	-	27260156	G402	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.3917856578071275	[17]	[0,25,17,19]	-5	hSpCas9	negative selection	6871100
20917979	20918002	22	+	27260156	G402	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.42176653968327704	[121]	[149,135,50,113]	-5	hSpCas9	negative selection	6871101
20933870	20933893	22	-	27260156	G402	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.19653104338539495	[689]	[1511,963,1055,428]	2	hSpCas9	negative selection	6871102
20934074	20934097	22	-	27260156	G402	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-2.8311281506105606	[189]	[34,13,16,61]	-9	hSpCas9	negative selection	6935370
20949752	20949775	22	-	27260156	G402	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.2563012405400188	[864]	[969,797,1082,696]	-3	hSpCas9	negative selection	6935371
20949715	20949738	22	+	27260156	G402	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.6112390016551248	[276]	[184,278,253,166]	-6	hSpCas9	negative selection	6935372
20918134	20918157	22	-	27260156	L33	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.2026107150089036	[17]	[15,5,9,15]	-4	hSpCas9	negative selection	6992351
20917979	20918002	22	+	27260156	L33	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.05419067151707657	[121]	[111,71,61,83]	-1	hSpCas9	negative selection	6992352
20933870	20933893	22	-	27260156	L33	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.0595589063140643	[689]	[690,256,458,599]	-1	hSpCas9	negative selection	6992353
20934074	20934097	22	-	27260156	L33	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.2114294605396394	[189]	[136,45,97,250]	-5	hSpCas9	negative selection	7056621
20949752	20949775	22	-	27260156	L33	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.012512505446498401	[864]	[865,343,560,891]	0	hSpCas9	negative selection	7056622
20949715	20949738	22	+	27260156	L33	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.2665697029439327	[276]	[223,129,144,149]	-6	hSpCas9	negative selection	7056623
20918134	20918157	22	-	27260156	K562	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-2.7307685671516593	[17]	[0,0,0,5]	-9	hSpCas9	negative selection	7113602
20917979	20918002	22	+	27260156	K562	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.562671397496393	[121]	[56,20,110,96]	-6	hSpCas9	negative selection	7113603
20933870	20933893	22	-	27260156	K562	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.39406931598951844	[689]	[397,313,355,746]	-5	hSpCas9	negative selection	7113604
20934074	20934097	22	-	27260156	K562	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-2.556223216190023	[189]	[7,78,13,15]	-9	hSpCas9	negative selection	7177872
20949752	20949775	22	-	27260156	K562	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.40262296355391	[864]	[809,231,756,527]	-5	hSpCas9	negative selection	7177873
20949715	20949738	22	+	27260156	K562	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-1.6037303079645477	[276]	[67,218,23,24]	-9	hSpCas9	negative selection	7177874
20918134	20918157	22	-	27260156	HT29	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-1.1503701237765052	[17]	[12,5,7,11]	-9	hSpCas9	negative selection	7234853
20917979	20918002	22	+	27260156	HT29	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.9100508474745141	[121]	[34,148,74,60]	-8	hSpCas9	negative selection	7234854
20933870	20933893	22	-	27260156	HT29	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.08042873229715525	[689]	[977,849,677,692]	-2	hSpCas9	negative selection	7234855
20934074	20934097	22	-	27260156	HT29	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.0511679231645576	[189]	[119,144,102,83]	-9	hSpCas9	negative selection	7299123
20949752	20949775	22	-	27260156	HT29	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.41010650862318787	[864]	[996,812,636,736]	-6	hSpCas9	negative selection	7299124
20949715	20949738	22	+	27260156	HT29	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.8025648451567986	[276]	[209,227,178,161]	-8	hSpCas9	negative selection	7299125
20918134	20918157	22	-	27260156	MHHES1	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.16987163222307977	[17]	[47,6,23,14]	3	hSpCas9	negative selection	7356104
20917979	20918002	22	+	27260156	MHHES1	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.12799719908548512	[121]	[112,174,57,150]	-2	hSpCas9	negative selection	7356105
20933870	20933893	22	-	27260156	MHHES1	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.16434480686922892	[689]	[1043,1109,911,524]	3	hSpCas9	negative selection	7356106
20934074	20934097	22	-	27260156	MHHES1	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.0185115577758128	[189]	[116,155,66,89]	-9	hSpCas9	negative selection	7420374
20949752	20949775	22	-	27260156	MHHES1	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.147487857490041	[864]	[1293,1266,892,918]	2	hSpCas9	negative selection	7420375
20949715	20949738	22	+	27260156	MHHES1	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.5472028011059731	[276]	[273,178,187,211]	-8	hSpCas9	negative selection	7420376
20918134	20918157	22	-	27260156	MEWO	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.09343117690671221	[17]	[18,9,18]	-2	hSpCas9	negative selection	7477355
20917979	20918002	22	+	27260156	MEWO	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.21128501548038514	[121]	[83,81,126]	-4	hSpCas9	negative selection	7477356
20933870	20933893	22	-	27260156	MEWO	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.060290799074448675	[689]	[663,599,601]	-1	hSpCas9	negative selection	7477357
20934074	20934097	22	-	27260156	MEWO	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.7726305690858379	[189]	[138,82,96]	-9	hSpCas9	negative selection	7541625
20949752	20949775	22	-	27260156	MEWO	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.04881419396863307	[864]	[861,632,867]	-1	hSpCas9	negative selection	7541626
20949715	20949738	22	+	27260156	MEWO	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.5186571271196962	[276]	[243,152,157]	-8	hSpCas9	negative selection	7541627
20918134	20918157	22	-	27260156	LNCAPCLONEFGC	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.49206197428950116	[17]	[15,9,8,10]	-6	hSpCas9	negative selection	7598606
20917979	20918002	22	+	27260156	LNCAPCLONEFGC	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.088046510241373	[121]	[86,102,142,88]	-1	hSpCas9	negative selection	7598607
20933870	20933893	22	-	27260156	LNCAPCLONEFGC	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.3545272570411816	[689]	[916,636,943,727]	5	hSpCas9	negative selection	7598608
20934074	20934097	22	-	27260156	LNCAPCLONEFGC	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.3402813161391025	[189]	[140,205,61,118]	-5	hSpCas9	negative selection	7662876
20949752	20949775	22	-	27260156	LNCAPCLONEFGC	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.12803858030099724	[864]	[988,830,979,641]	2	hSpCas9	negative selection	7662877
20949715	20949738	22	+	27260156	LNCAPCLONEFGC	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.3484007887658982	[276]	[185,183,248,177]	-5	hSpCas9	negative selection	7662878
20918134	20918157	22	-	27260156	PANC0327	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	1.232981786068167	[17]	[17,4,84,44]	9	hSpCas9	negative selection	7719857
20917979	20918002	22	+	27260156	PANC0327	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.927799060170603	[121]	[77,60,25,63]	-8	hSpCas9	negative selection	7719858
20933870	20933893	22	-	27260156	PANC0327	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.504829503906661	[689]	[472,222,465,595]	-6	hSpCas9	negative selection	7719859
20934074	20934097	22	-	27260156	PANC0327	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-2.229093224786818	[189]	[83,19,33,11]	-9	hSpCas9	negative selection	7784127
20949752	20949775	22	-	27260156	PANC0327	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.6454196002972041	[864]	[513,519,499,428]	-7	hSpCas9	negative selection	7784128
20949715	20949738	22	+	27260156	PANC0327	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.811982240681818	[276]	[53,136,194,167]	-8	hSpCas9	negative selection	7784129
20918134	20918157	22	-	27260156	NCIH2009	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-2.290378843196331	[17]	[7,3,3]	-9	hSpCas9	negative selection	7841108
20917979	20918002	22	+	27260156	NCIH2009	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-1.523465318114825	[121]	[118,35,34]	-9	hSpCas9	negative selection	7841109
20933870	20933893	22	-	27260156	NCIH2009	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.05164955697433549	[689]	[1054,902,855]	0	hSpCas9	negative selection	7841110
20934074	20934097	22	-	27260156	NCIH2009	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.5496891133615516	[189]	[109,128,35]	-9	hSpCas9	negative selection	7905378
20949752	20949775	22	-	27260156	NCIH2009	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.5145303025510513	[864]	[1136,795,661]	-6	hSpCas9	negative selection	7905379
20949715	20949738	22	+	27260156	NCIH2009	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-1.8118200195580076	[276]	[147,108,80]	-9	hSpCas9	negative selection	7905380
20918134	20918157	22	-	27260156	NCIH1373	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.27374729179148183	[17]	[2,9,72,1]	2	hSpCas9	negative selection	7962359
20917979	20918002	22	+	27260156	NCIH1373	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-1.8416266004566841	[121]	[97,11,9,11]	-9	hSpCas9	negative selection	7962360
20933870	20933893	22	-	27260156	NCIH1373	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.1956035362727579	[689]	[812,552,723,167]	-2	hSpCas9	negative selection	7962361
20934074	20934097	22	-	27260156	NCIH1373	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-2.3490070576192155	[189]	[63,0,70,9]	-9	hSpCas9	negative selection	8026629
20949752	20949775	22	-	27260156	NCIH1373	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.827616439716074	[864]	[737,351,583,146]	-7	hSpCas9	negative selection	8026630
20949715	20949738	22	+	27260156	NCIH1373	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-2.244093720471893	[276]	[106,50,50,15]	-9	hSpCas9	negative selection	8026631
20918134	20918157	22	-	27260156	PATU8902	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-0.10109597352549127	[17]	[49,0,2,46]	-1	hSpCas9	negative selection	8083610
20917979	20918002	22	+	27260156	PATU8902	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-2.1490380306232613	[121]	[88,11,32,16]	-9	hSpCas9	negative selection	8083611
20933870	20933893	22	-	27260156	PATU8902	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.10713738324912248	[689]	[489,1258,821,1031]	-1	hSpCas9	negative selection	8083612
20934074	20934097	22	-	27260156	PATU8902	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.7112634157744093	[189]	[201,251,26,203]	-6	hSpCas9	negative selection	8147880
20949752	20949775	22	-	27260156	PATU8902	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.11797284495014226	[864]	[1308,1163,926,1071]	-1	hSpCas9	negative selection	8147881
20949715	20949738	22	+	27260156	PATU8902	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-1.908049835726608	[276]	[126,53,132,85]	-9	hSpCas9	negative selection	8147882
20918134	20918157	22	-	27260156	PANC1	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-1.586167396793936	[17]	[1,6,6,4]	-9	hSpCas9	negative selection	8204861
20917979	20918002	22	+	27260156	PANC1	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.6296223473320275	[121]	[87,32,104,40]	-7	hSpCas9	negative selection	8204862
20933870	20933893	22	-	27260156	PANC1	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.34009987973237454	[689]	[586,535,338,420]	-5	hSpCas9	negative selection	8204863
20934074	20934097	22	-	27260156	PANC1	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.6011226244627703	[189]	[220,92,45,68]	-7	hSpCas9	negative selection	8269131
20949752	20949775	22	-	27260156	PANC1	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.8329414840149562	[864]	[410,605,350,343]	-8	hSpCas9	negative selection	8269132
20949715	20949738	22	+	27260156	PANC1	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-1.4213303508087929	[276]	[117,23,75,116]	-9	hSpCas9	negative selection	8269133
20918134	20918157	22	-	27260156	PANC0813	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.11384854656328702	[17]	[9,29,4,43]	1	hSpCas9	negative selection	8326112
20917979	20918002	22	+	27260156	PANC0813	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.38641820155027773	[121]	[139,105,118,77]	-5	hSpCas9	negative selection	8326113
20933870	20933893	22	-	27260156	PANC0813	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.07729577881524047	[689]	[847,574,790,859]	-1	hSpCas9	negative selection	8326114
20934074	20934097	22	-	27260156	PANC0813	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.4674038879729525	[189]	[59,60,67,128]	-9	hSpCas9	negative selection	8390382
20949752	20949775	22	-	27260156	PANC0813	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.5789878748998735	[864]	[817,844,561,515]	-7	hSpCas9	negative selection	8390383
20949715	20949738	22	+	27260156	PANC0813	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.6836780195524417	[276]	[233,120,269,188]	-7	hSpCas9	negative selection	8390384
20918134	20918157	22	-	27260156	RDES	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.7343922978619375	[17]	[29,31,49,24]	9	hSpCas9	negative selection	8447363
20917979	20918002	22	+	27260156	RDES	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.06710402743799149	[121]	[136,74,196,128]	-1	hSpCas9	negative selection	8447364
20933870	20933893	22	-	27260156	RDES	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.06012357147383507	[689]	[701,760,863,1020]	1	hSpCas9	negative selection	8447365
20934074	20934097	22	-	27260156	RDES	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.0330843097397113	[189]	[78,85,112,162]	-9	hSpCas9	negative selection	8511633
20949752	20949775	22	-	27260156	RDES	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.1311127172574763	[864]	[936,951,1131,1397]	2	hSpCas9	negative selection	8511634
20949715	20949738	22	+	27260156	RDES	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.31021186258474565	[276]	[160,254,293,346]	-5	hSpCas9	negative selection	8511635
20918134	20918157	22	-	27260156	PC3	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	-1.395440167923656	[17]	[1,3,4,17]	-9	hSpCas9	negative selection	8568614
20917979	20918002	22	+	27260156	PC3	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.26019707502441225	[121]	[63,107,274,216]	5	hSpCas9	negative selection	8568615
20933870	20933893	22	-	27260156	PC3	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.33920255914183106	[689]	[482,875,886,1353]	7	hSpCas9	negative selection	8568616
20934074	20934097	22	-	27260156	PC3	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.8805470851719739	[189]	[83,96,206,57]	-9	hSpCas9	negative selection	8632884
20949752	20949775	22	-	27260156	PC3	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.13653129275527043	[864]	[564,776,1045,863]	-3	hSpCas9	negative selection	8632885
20949715	20949738	22	+	27260156	PC3	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.7653569779726881	[276]	[83,226,264,128]	-9	hSpCas9	negative selection	8632886
20918134	20918157	22	-	27260156	PATU8988T	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	1.282923031383405	[17]	[67,45,13,41]	9	hSpCas9	negative selection	8689865
20917979	20918002	22	+	27260156	PATU8988T	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.06624535436748413	[121]	[66,64,245,61]	-1	hSpCas9	negative selection	8689866
20933870	20933893	22	-	27260156	PATU8988T	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.4358144126311335	[689]	[504,549,368,559]	-6	hSpCas9	negative selection	8689867
20934074	20934097	22	-	27260156	PATU8988T	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.6780627183301915	[189]	[27,102,34,68]	-9	hSpCas9	negative selection	8754135
20949752	20949775	22	-	27260156	PATU8988T	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.4317073500385407	[864]	[512,679,646,645]	-6	hSpCas9	negative selection	8754136
20949715	20949738	22	+	27260156	PATU8988T	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-1.4263633622578653	[276]	[116,194,42,48]	-9	hSpCas9	negative selection	8754137
20918134	20918157	22	-	27260156	T47D	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.9317228688561454	[17]	[28,50,38,39]	9	hSpCas9	negative selection	8811116
20917979	20918002	22	+	27260156	T47D	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.3155926058237193	[121]	[171,159,210,164]	6	hSpCas9	negative selection	8811117
20933870	20933893	22	-	27260156	T47D	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.0019670047296770354	[689]	[820,724,760,923]	0	hSpCas9	negative selection	8811118
20934074	20934097	22	-	27260156	T47D	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.8123298754010437	[189]	[56,157,129,156]	-9	hSpCas9	negative selection	8875386
20949752	20949775	22	-	27260156	T47D	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.048953460721301356	[864]	[1000,953,866,1080]	-1	hSpCas9	negative selection	8875387
20949715	20949738	22	+	27260156	T47D	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.2070650732974263	[276]	[263,221,312,324]	-4	hSpCas9	negative selection	8875388
20918134	20918157	22	-	27260156	SU8686	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.628847928289324	[17]	[20,22,51,13]	9	hSpCas9	negative selection	8932367
20917979	20918002	22	+	27260156	SU8686	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.12503969055732256	[121]	[79,107,72,198]	-2	hSpCas9	negative selection	8932368
20933870	20933893	22	-	27260156	SU8686	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.34525359351636353	[689]	[814,757,931,1009]	6	hSpCas9	negative selection	8932369
20934074	20934097	22	-	27260156	SU8686	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.6211315979483556	[189]	[76,118,128,178]	-7	hSpCas9	negative selection	8996637
20949752	20949775	22	-	27260156	SU8686	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.04378532804492041	[864]	[794,832,689,1036]	-1	hSpCas9	negative selection	8996638
20949715	20949738	22	+	27260156	SU8686	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	0.05738184441177174	[276]	[165,190,293,560]	1	hSpCas9	negative selection	8996639
20918134	20918157	22	-	27260156	SKES1	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.27745237436811276	[17]	[32,10,9,31]	6	hSpCas9	negative selection	9053618
20917979	20918002	22	+	27260156	SKES1	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.46089446826558933	[121]	[190,159,195,127]	8	hSpCas9	negative selection	9053619
20933870	20933893	22	-	27260156	SKES1	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.01576088244948437	[689]	[1009,652,512,594]	0	hSpCas9	negative selection	9053620
20934074	20934097	22	-	27260156	SKES1	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.0157795719619576	[189]	[109,79,115,70]	-9	hSpCas9	negative selection	9117888
20949752	20949775	22	-	27260156	SKES1	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.02310179285251568	[864]	[1039,984,907,629]	0	hSpCas9	negative selection	9117889
20949715	20949738	22	+	27260156	SKES1	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.15051041847253166	[276]	[262,233,233,260]	-3	hSpCas9	negative selection	9117890
20918134	20918157	22	-	27260156	TOV112D	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.28089716374550644	[17]	[36,9,19,18]	5	hSpCas9	negative selection	9174869
20917979	20918002	22	+	27260156	TOV112D	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.005926920068709096	[121]	[76,103,159,136]	0	hSpCas9	negative selection	9174870
20933870	20933893	22	-	27260156	TOV112D	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.07403064683098959	[689]	[760,1055,726,455]	1	hSpCas9	negative selection	9174871
20934074	20934097	22	-	27260156	TOV112D	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.4624764603995266	[189]	[248,97,78,125]	-7	hSpCas9	negative selection	9239139
20949752	20949775	22	-	27260156	TOV112D	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	-0.07797375197409062	[864]	[921,994,845,576]	-1	hSpCas9	negative selection	9239140
20949715	20949738	22	+	27260156	TOV112D	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.7306808509138389	[276]	[71,216,190,191]	-9	hSpCas9	negative selection	9239141
20918134	20918157	22	-	27260156	TC71	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	1.1249040479429806	[17]	[27,21,40,79]	9	hSpCas9	negative selection	9296120
20917979	20918002	22	+	27260156	TC71	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	-0.03157752509730227	[121]	[139,84,132,154]	-1	hSpCas9	negative selection	9296121
20933870	20933893	22	-	27260156	TC71	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	-0.0013911792616304597	[689]	[635,789,703,834]	0	hSpCas9	negative selection	9296122
20934074	20934097	22	-	27260156	TC71	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-0.6160184651251284	[189]	[142,131,99,158]	-9	hSpCas9	negative selection	9360390
20949752	20949775	22	-	27260156	TC71	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.14252950155840172	[864]	[1181,801,946,1170]	3	hSpCas9	negative selection	9360391
20949715	20949738	22	+	27260156	TC71	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.319632118743578	[276]	[214,231,218,289]	-7	hSpCas9	negative selection	9360392
20918134	20918157	22	-	27260156	TC32	viability	CCCGATCTTAAAACGGCGGTTGG	CRKL	ENSG00000099942	0.5233769118060003	[17]	[4,19,26,49]	8	hSpCas9	negative selection	9417371
20917979	20918002	22	+	27260156	TC32	viability	TATGGGGCCGGTGTCTCGCCAGG	CRKL	ENSG00000099942	0.006263031649749173	[121]	[131,111,79,121]	0	hSpCas9	negative selection	9417372
20933870	20933893	22	-	27260156	TC32	viability	AGGTCTTCGGCATCATTCCCAGG	CRKL	ENSG00000099942	0.22424584848297002	[689]	[534,685,882,968]	4	hSpCas9	negative selection	9417373
20934074	20934097	22	-	27260156	TC32	viability	GGTTGAGCGTATGCATGAGCAGG	CRKL	ENSG00000099942	-1.7863392243431249	[189]	[13,36,87,83]	-9	hSpCas9	negative selection	9481641
20949752	20949775	22	-	27260156	TC32	viability	CGTTCACTTCGCCTTCCCACTGG	CRKL	ENSG00000099942	0.3038085983518094	[864]	[924,880,1160,1070]	5	hSpCas9	negative selection	9481642
20949715	20949738	22	+	27260156	TC32	viability	GTGACATCGTGAAAGTCACAAGG	CRKL	ENSG00000099942	-0.23309294786164247	[276]	[155,159,206,388]	-4	hSpCas9	negative selection	9481643
20917945	20917968	22	-	27869803	HPAFII	viability after 27 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-1.6040960487314735	[388]	[141,4,NaN]	-7	hSpCas9	negative selection	9579914
20917986	20918009	22	-	27869803	HPAFII	viability after 27 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-1.641080234016352	[191]	[9,50,NaN]	-8	hSpCas9	negative selection	9579915
20933818	20933841	22	-	27869803	HPAFII	viability after 27 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-1.1810361079370766	[88]	[0,36,NaN]	-7	hSpCas9	negative selection	9579916
20933948	20933971	22	+	27869803	HPAFII	viability after 27 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-1.7433552694553058	[296]	[38,52,NaN]	-8	hSpCas9	negative selection	9579917
20949754	20949777	22	+	27869803	HPAFII	viability after 27 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.043604250715186865	[202]	[139,84,NaN]	0	hSpCas9	negative selection	9579918
20949763	20949786	22	+	27869803	HPAFII	viability after 27 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.425937301260069	[488]	[120,249,NaN]	-3	hSpCas9	negative selection	9579919
20917945	20917968	22	-	27869803	HPAFII	viability after 15 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-1.5907699267314792	[388]	[279,50,NaN]	-8	hSpCas9	negative selection	9662363
20917986	20918009	22	-	27869803	HPAFII	viability after 15 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.9562389909186928	[191]	[122,95,NaN]	-7	hSpCas9	negative selection	9662364
20933818	20933841	22	-	27869803	HPAFII	viability after 15 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-0.6729020859862962	[88]	[22,82,NaN]	-6	hSpCas9	negative selection	9662365
20933948	20933971	22	+	27869803	HPAFII	viability after 15 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-0.7066429184138756	[296]	[210,185,NaN]	-6	hSpCas9	negative selection	9662366
20949754	20949777	22	+	27869803	HPAFII	viability after 15 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.05981859497352909	[202]	[293,185,NaN]	0	hSpCas9	negative selection	9662367
20949763	20949786	22	+	27869803	HPAFII	viability after 15 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.33792332973310624	[488]	[691,646,NaN]	4	hSpCas9	negative selection	9662368
20917945	20917968	22	-	27869803	ASPC1	viability after 36 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	0.02188760726404615	[702]	[436,205,148]	0	hSpCas9	negative selection	9744812
20917986	20918009	22	-	27869803	ASPC1	viability after 36 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.2997169318058607	[388]	[195,93,61]	-3	hSpCas9	negative selection	9744813
20933818	20933841	22	-	27869803	ASPC1	viability after 36 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	0.006294367275884172	[211]	[73,165,0]	0	hSpCas9	negative selection	9744814
20933948	20933971	22	+	27869803	ASPC1	viability after 36 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-1.964118995069527	[875]	[121,71,51]	-9	hSpCas9	negative selection	9744815
20949754	20949777	22	+	27869803	ASPC1	viability after 36 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.08029256533766105	[514]	[66,336,107]	-1	hSpCas9	negative selection	9744816
20949763	20949786	22	+	27869803	ASPC1	viability after 36 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	0.11363064224959274	[1650]	[889,736,339]	1	hSpCas9	negative selection	9744817
20917945	20917968	22	-	27869803	PATU8988S	viability after 35 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-0.12861747091674924	[706]	[241,278,NaN]	-1	hSpCas9	negative selection	9827261
20917986	20918009	22	-	27869803	PATU8988S	viability after 35 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.5212107339093546	[268]	[70,79,NaN]	-5	hSpCas9	negative selection	9827262
20933818	20933841	22	-	27869803	PATU8988S	viability after 35 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-0.6386438187931167	[248]	[26,101,NaN]	-6	hSpCas9	negative selection	9827263
20933948	20933971	22	+	27869803	PATU8988S	viability after 35 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-0.8249518038023591	[806]	[171,194,NaN]	-7	hSpCas9	negative selection	9827264
20949754	20949777	22	+	27869803	PATU8988S	viability after 35 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.15228576090756107	[392]	[132,218,NaN]	1	hSpCas9	negative selection	9827265
20949763	20949786	22	+	27869803	PATU8988S	viability after 35 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.395313897823367	[1503]	[484,435,NaN]	-4	hSpCas9	negative selection	9827266
20917945	20917968	22	-	27869803	PATU8988S	viability after 31 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-0.5677464173907848	[706]	[176,206,NaN]	-6	hSpCas9	negative selection	9909710
20917986	20918009	22	-	27869803	PATU8988S	viability after 31 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-0.9848466563622313	[268]	[40,70,NaN]	-7	hSpCas9	negative selection	9909711
20933818	20933841	22	-	27869803	PATU8988S	viability after 31 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-0.5159829237884475	[248]	[35,111,NaN]	-5	hSpCas9	negative selection	9909712
20933948	20933971	22	+	27869803	PATU8988S	viability after 31 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-0.6428855538918793	[806]	[213,195,NaN]	-6	hSpCas9	negative selection	9909713
20949754	20949777	22	+	27869803	PATU8988S	viability after 31 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.4623935494060319	[392]	[185,253,NaN]	5	hSpCas9	negative selection	9909714
20949763	20949786	22	+	27869803	PATU8988S	viability after 31 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.24885040309672335	[1503]	[388,651,NaN]	-3	hSpCas9	negative selection	9909715
20917945	20917968	22	-	27869803	HPAFII	viability after 35 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-2.2926411728332123	[388]	[74,0,NaN]	-8	hSpCas9	negative selection	9992159
20917986	20918009	22	-	27869803	HPAFII	viability after 35 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-3.135687275254038	[191]	[11,9,NaN]	-8	hSpCas9	negative selection	9992160
20933818	20933841	22	-	27869803	HPAFII	viability after 35 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-3.3720396990996644	[88]	[1,6,NaN]	-8	hSpCas9	negative selection	9992161
20933948	20933971	22	+	27869803	HPAFII	viability after 35 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-3.413111723912335	[296]	[7,20,NaN]	-8	hSpCas9	negative selection	9992162
20949754	20949777	22	+	27869803	HPAFII	viability after 35 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	0.04821924957321541	[202]	[157,47,NaN]	0	hSpCas9	negative selection	9992163
20949763	20949786	22	+	27869803	HPAFII	viability after 35 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-1.7639664061963096	[488]	[86,56,NaN]	-7	hSpCas9	negative selection	9992164
20917945	20917968	22	-	27869803	HPAFII	viability after 31 days	GCGGTCCGAGGAGTCGAACCTGG	CRKL	ENSG00000099942	-1.916366400067893	[388]	[109,0,NaN]	-8	hSpCas9	negative selection	10074608
20917986	20918009	22	-	27869803	HPAFII	viability after 31 days	TGCGCCTCCTGGCGAGACACCGG	CRKL	ENSG00000099942	-3.6246656294634785	[191]	[13,2,NaN]	-9	hSpCas9	negative selection	10074609
20933818	20933841	22	-	27869803	HPAFII	viability after 31 days	GGTTATCTTCTGCTGTAGGCAGG	CRKL	ENSG00000099942	-2.3070994979021675	[88]	[0,19,NaN]	-8	hSpCas9	negative selection	10074610
20933948	20933971	22	+	27869803	HPAFII	viability after 31 days	TGGAGTGCCCGGAACAAGGATGG	CRKL	ENSG00000099942	-3.3803040045600814	[296]	[4,27,NaN]	-9	hSpCas9	negative selection	10074611
20949754	20949777	22	+	27869803	HPAFII	viability after 31 days	AGTGGGAAGGCGAAGTGAACGGG	CRKL	ENSG00000099942	-0.18769638802638078	[202]	[122,74,NaN]	-1	hSpCas9	negative selection	10074612
20949763	20949786	22	+	27869803	HPAFII	viability after 31 days	GCGAAGTGAACGGGCGCAAAGGG	CRKL	ENSG00000099942	-0.4678954271547694	[488]	[151,248,NaN]	-3	hSpCas9	negative selection	10074613
20917939	20917962	22	-	28162770	P31FUJ	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	2.5586111737742043	[25]	[179]	9	hSpCas9	negative selection	10138155
20918183	20918206	22	-	28162770	P31FUJ	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.6478397036932223	[207]	[155]	-5	hSpCas9	negative selection	10138156
20918111	20918134	22	-	28162770	P31FUJ	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.17810267948955172	[436]	[580]	1	hSpCas9	negative selection	10138157
20918138	20918161	22	-	28162770	P31FUJ	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.7322640054762342	[208]	[407]	8	hSpCas9	negative selection	10138158
20933776	20933799	22	+	28162770	P31FUJ	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	-0.02502430397352784	[651]	[752]	0	hSpCas9	negative selection	10138159
20918221	20918244	22	-	28162770	P31FUJ	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	-0.2950864826687215	[141]	[135]	-3	hSpCas9	negative selection	10138160
20933925	20933948	22	+	28162770	P31FUJ	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	0.15565050927350382	[177]	[232]	1	hSpCas9	negative selection	10138161
20934210	20934233	22	-	28162770	P31FUJ	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-0.16098504380489698	[528]	[555]	-1	hSpCas9	negative selection	10138162
20917964	20917987	22	-	28162770	P31FUJ	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	0.266471832032497	[236]	[334]	3	hSpCas9	negative selection	10138163
20918024	20918047	22	-	28162770	P31FUJ	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	0.2281715790313239	[84]	[116]	2	hSpCas9	negative selection	10138164
20917939	20917962	22	-	28162770	TF1	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10307521
20918183	20918206	22	-	28162770	TF1	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10307522
20918111	20918134	22	-	28162770	TF1	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	NaN	[NaN]	[349]	1	hSpCas9	negative selection	10307523
20918138	20918161	22	-	28162770	TF1	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	NaN	[NaN]	[315]	1	hSpCas9	negative selection	10307524
20933776	20933799	22	+	28162770	TF1	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	NaN	[NaN]	[500]	1	hSpCas9	negative selection	10307525
20918221	20918244	22	-	28162770	TF1	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10307526
20933925	20933948	22	+	28162770	TF1	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10307527
20934210	20934233	22	-	28162770	TF1	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	NaN	[NaN]	[442]	1	hSpCas9	negative selection	10307528
20917964	20917987	22	-	28162770	TF1	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10307529
20918024	20918047	22	-	28162770	TF1	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10307530
20917939	20917962	22	-	28162770	SKM1	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.0524674198941355	[11]	[21]	0	hSpCas9	negative selection	10476887
20918183	20918206	22	-	28162770	SKM1	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.9880116494609346	[45]	[40]	-6	hSpCas9	negative selection	10476888
20918111	20918134	22	-	28162770	SKM1	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	-0.5365994791597571	[127]	[155]	-4	hSpCas9	negative selection	10476889
20918138	20918161	22	-	28162770	SKM1	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.43383720640758444	[66]	[159]	4	hSpCas9	negative selection	10476890
20933776	20933799	22	+	28162770	SKM1	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	-0.04681678162530911	[148]	[254]	0	hSpCas9	negative selection	10476891
20918221	20918244	22	-	28162770	SKM1	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.6242545318675584	[39]	[108]	6	hSpCas9	negative selection	10476892
20933925	20933948	22	+	28162770	SKM1	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.6325238991582925	[56]	[64]	-5	hSpCas9	negative selection	10476893
20934210	20934233	22	-	28162770	SKM1	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-0.06243467491866683	[113]	[192]	0	hSpCas9	negative selection	10476894
20917964	20917987	22	-	28162770	SKM1	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	1.0212727982905414	[33]	[121]	8	hSpCas9	negative selection	10476895
20918024	20918047	22	-	28162770	SKM1	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-0.8220016980220057	[17]	[17]	-6	hSpCas9	negative selection	10476896
20917939	20917962	22	-	28162770	SKM1	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.0524674198941355	[11]	[21]	0	hSpCas9	negative selection	10646253
20918183	20918206	22	-	28162770	SKM1	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.9880116494609346	[45]	[40]	-6	hSpCas9	negative selection	10646254
20918111	20918134	22	-	28162770	SKM1	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	-0.5365994791597571	[127]	[155]	-4	hSpCas9	negative selection	10646255
20918138	20918161	22	-	28162770	SKM1	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.43383720640758444	[66]	[159]	4	hSpCas9	negative selection	10646256
20933776	20933799	22	+	28162770	SKM1	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	-0.04681678162530911	[148]	[254]	0	hSpCas9	negative selection	10646257
20918221	20918244	22	-	28162770	SKM1	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.6242545318675584	[39]	[108]	6	hSpCas9	negative selection	10646258
20933925	20933948	22	+	28162770	SKM1	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.6325238991582925	[56]	[64]	-5	hSpCas9	negative selection	10646259
20934210	20934233	22	-	28162770	SKM1	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-0.06243467491866683	[113]	[192]	0	hSpCas9	negative selection	10646260
20917964	20917987	22	-	28162770	SKM1	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	1.0212727982905414	[33]	[121]	8	hSpCas9	negative selection	10646261
20918024	20918047	22	-	28162770	SKM1	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-0.8220016980220057	[17]	[17]	-6	hSpCas9	negative selection	10646262
20917939	20917962	22	-	28162770	PL21	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	-1.2058527451865166	[52]	[9]	-7	hSpCas9	negative selection	10815619
20918183	20918206	22	-	28162770	PL21	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	1.2089098241170522	[163]	[164]	8	hSpCas9	negative selection	10815620
20918111	20918134	22	-	28162770	PL21	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.12049627769828009	[390]	[184]	1	hSpCas9	negative selection	10815621
20918138	20918161	22	-	28162770	PL21	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.5842107630849502	[258]	[168]	5	hSpCas9	negative selection	10815622
20933776	20933799	22	+	28162770	PL21	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.3532964025507406	[499]	[277]	3	hSpCas9	negative selection	10815623
20918221	20918244	22	-	28162770	PL21	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	1.5693734241550392	[143]	[185]	9	hSpCas9	negative selection	10815624
20933925	20933948	22	+	28162770	PL21	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	1.5261259259510358	[141]	[177]	9	hSpCas9	negative selection	10815625
20934210	20934233	22	-	28162770	PL21	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.7895617634011761	[322]	[242]	6	hSpCas9	negative selection	10815626
20917964	20917987	22	-	28162770	PL21	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	0.7011503368780168	[170]	[120]	6	hSpCas9	negative selection	10815627
20918024	20918047	22	-	28162770	PL21	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-1.3359132857508893	[86]	[14]	-7	hSpCas9	negative selection	10815628
20917939	20917962	22	-	28162770	P31FUJ	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	2.5586111737742043	[25]	[179]	9	hSpCas9	negative selection	10984985
20918183	20918206	22	-	28162770	P31FUJ	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.6478397036932223	[207]	[155]	-5	hSpCas9	negative selection	10984986
20918111	20918134	22	-	28162770	P31FUJ	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.17810267948955172	[436]	[580]	1	hSpCas9	negative selection	10984987
20918138	20918161	22	-	28162770	P31FUJ	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.7322640054762342	[208]	[407]	8	hSpCas9	negative selection	10984988
20933776	20933799	22	+	28162770	P31FUJ	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	-0.02502430397352784	[651]	[752]	0	hSpCas9	negative selection	10984989
20918221	20918244	22	-	28162770	P31FUJ	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	-0.2950864826687215	[141]	[135]	-3	hSpCas9	negative selection	10984990
20933925	20933948	22	+	28162770	P31FUJ	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	0.15565050927350382	[177]	[232]	1	hSpCas9	negative selection	10984991
20934210	20934233	22	-	28162770	P31FUJ	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-0.16098504380489698	[528]	[555]	-1	hSpCas9	negative selection	10984992
20917964	20917987	22	-	28162770	P31FUJ	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	0.266471832032497	[236]	[334]	3	hSpCas9	negative selection	10984993
20918024	20918047	22	-	28162770	P31FUJ	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	0.2281715790313239	[84]	[116]	2	hSpCas9	negative selection	10984994
20917939	20917962	22	-	28162770	OCIAML5	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.671495385193016	[39]	[114]	6	hSpCas9	negative selection	11154351
20918183	20918206	22	-	28162770	OCIAML5	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	0.23075986026562373	[109]	[232]	2	hSpCas9	negative selection	11154352
20918111	20918134	22	-	28162770	OCIAML5	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.5432825934927348	[248]	[654]	5	hSpCas9	negative selection	11154353
20918138	20918161	22	-	28162770	OCIAML5	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	-0.2773724055966678	[140]	[209]	-2	hSpCas9	negative selection	11154354
20933776	20933799	22	+	28162770	OCIAML5	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.1974535649798017	[314]	[651]	1	hSpCas9	negative selection	11154355
20918221	20918244	22	-	28162770	OCIAML5	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.4980321967145266	[70]	[180]	4	hSpCas9	negative selection	11154356
20933925	20933948	22	+	28162770	OCIAML5	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	0.3277544667208154	[112]	[255]	2	hSpCas9	negative selection	11154357
20934210	20934233	22	-	28162770	OCIAML5	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.2687878240103885	[308]	[671]	2	hSpCas9	negative selection	11154358
20917964	20917987	22	-	28162770	OCIAML5	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	1.5073362294420285	[75]	[389]	9	hSpCas9	negative selection	11154359
20918024	20918047	22	-	28162770	OCIAML5	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-0.8885924468891111	[39]	[38]	-5	hSpCas9	negative selection	11154360
20917939	20917962	22	-	28162770	EOL1	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.019406957911975553	[102]	[54]	0	hSpCas9	negative selection	11323717
20918183	20918206	22	-	28162770	EOL1	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.3198709560959123	[153]	[64]	-2	hSpCas9	negative selection	11323718
20918111	20918134	22	-	28162770	EOL1	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.5582546061431091	[775]	[601]	5	hSpCas9	negative selection	11323719
20918138	20918161	22	-	28162770	EOL1	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.6784555147551666	[490]	[413]	6	hSpCas9	negative selection	11323720
20933776	20933799	22	+	28162770	EOL1	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.3669252524160229	[966]	[656]	3	hSpCas9	negative selection	11323721
20918221	20918244	22	-	28162770	EOL1	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	-0.4253946994864244	[259]	[101]	-3	hSpCas9	negative selection	11323722
20933925	20933948	22	+	28162770	EOL1	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.13375086899413258	[201]	[96]	-1	hSpCas9	negative selection	11323723
20934210	20934233	22	-	28162770	EOL1	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.21929103713166664	[524]	[321]	2	hSpCas9	negative selection	11323724
20917964	20917987	22	-	28162770	EOL1	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-0.4068613763277131	[228]	[90]	-3	hSpCas9	negative selection	11323725
20918024	20918047	22	-	28162770	EOL1	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-2.314918163124855	[84]	[8]	-8	hSpCas9	negative selection	11323726
20917939	20917962	22	-	28162770	MOLM13	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	-0.09398950606353607	[61]	[41]	0	hSpCas9	negative selection	11493083
20918183	20918206	22	-	28162770	MOLM13	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.8821440510231373	[310]	[121]	-5	hSpCas9	negative selection	11493084
20918111	20918134	22	-	28162770	MOLM13	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.13063300317612803	[685]	[542]	0	hSpCas9	negative selection	11493085
20918138	20918161	22	-	28162770	MOLM13	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.28479861031543163	[343]	[302]	2	hSpCas9	negative selection	11493086
20933776	20933799	22	+	28162770	MOLM13	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	1.3838457855914408	[697]	[1316]	9	hSpCas9	negative selection	11493087
20918221	20918244	22	-	28162770	MOLM13	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	-0.9244280412341814	[167]	[63]	-5	hSpCas9	negative selection	11493088
20933925	20933948	22	+	28162770	MOLM13	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.9795695954266425	[209]	[76]	-5	hSpCas9	negative selection	11493089
20934210	20934233	22	-	28162770	MOLM13	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-1.0721606973010032	[505]	[173]	-5	hSpCas9	negative selection	11493090
20917964	20917987	22	-	28162770	MOLM13	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-0.23110836242260688	[249]	[153]	-1	hSpCas9	negative selection	11493091
20918024	20918047	22	-	28162770	MOLM13	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-1.37713595847908	[96]	[26]	-6	hSpCas9	negative selection	11493092
20917939	20917962	22	-	28162770	HEL	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.7236588273839246	[51]	[54]	6	hSpCas9	negative selection	11662449
20918183	20918206	22	-	28162770	HEL	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-1.1684995245444751	[185]	[52]	-6	hSpCas9	negative selection	11662450
20918111	20918134	22	-	28162770	HEL	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.09471134155812422	[616]	[421]	0	hSpCas9	negative selection	11662451
20918138	20918161	22	-	28162770	HEL	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.06409010521140324	[341]	[228]	0	hSpCas9	negative selection	11662452
20933776	20933799	22	+	28162770	HEL	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.8365230296552209	[632]	[723]	7	hSpCas9	negative selection	11662453
20918221	20918244	22	-	28162770	HEL	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.7955476752797495	[178]	[198]	7	hSpCas9	negative selection	11662454
20933925	20933948	22	+	28162770	HEL	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	0.7698507499036963	[151]	[165]	6	hSpCas9	negative selection	11662455
20934210	20934233	22	-	28162770	HEL	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	-0.09769895407265428	[415]	[248]	0	hSpCas9	negative selection	11662456
20917964	20917987	22	-	28162770	HEL	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	0.41890587630469417	[166]	[142]	3	hSpCas9	negative selection	11662457
20918024	20918047	22	-	28162770	HEL	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	0.12489052713773763	[62]	[43]	1	hSpCas9	negative selection	11662458
20917939	20917962	22	-	28162770	MV411	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.31063137726996914	[66]	[69]	2	hSpCas9	negative selection	11831815
20918183	20918206	22	-	28162770	MV411	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.5661493249863434	[115]	[65]	-4	hSpCas9	negative selection	11831816
20918111	20918134	22	-	28162770	MV411	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	-1.231534254250167	[445]	[159]	-7	hSpCas9	negative selection	11831817
20918138	20918161	22	-	28162770	MV411	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.25845054350519314	[260]	[262]	2	hSpCas9	negative selection	11831818
20933776	20933799	22	+	28162770	MV411	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.276642901167802	[488]	[498]	2	hSpCas9	negative selection	11831819
20918221	20918244	22	-	28162770	MV411	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	-0.3956279045019492	[113]	[72]	-3	hSpCas9	negative selection	11831820
20933925	20933948	22	+	28162770	MV411	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-1.4128130772426182	[176]	[55]	-7	hSpCas9	negative selection	11831821
20934210	20934233	22	-	28162770	MV411	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.46034476345578446	[326]	[378]	4	hSpCas9	negative selection	11831822
20917964	20917987	22	-	28162770	MV411	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	0.02984611571014867	[149]	[128]	0	hSpCas9	negative selection	11831823
20918024	20918047	22	-	28162770	MV411	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	0.7910592561230321	[58]	[85]	7	hSpCas9	negative selection	11831824
20917939	20917962	22	-	28162770	MONOMAC1	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.27503159725566917	[30]	[42]	2	hSpCas9	negative selection	12001181
20918183	20918206	22	-	28162770	MONOMAC1	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	-0.16348428734852716	[84]	[86]	-1	hSpCas9	negative selection	12001182
20918111	20918134	22	-	28162770	MONOMAC1	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.5361396574935384	[304]	[506]	5	hSpCas9	negative selection	12001183
20918138	20918161	22	-	28162770	MONOMAC1	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	-0.09244794578235382	[132]	[142]	-1	hSpCas9	negative selection	12001184
20933776	20933799	22	+	28162770	MONOMAC1	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.05311626747750764	[374]	[445]	0	hSpCas9	negative selection	12001185
20918221	20918244	22	-	28162770	MONOMAC1	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.004597014110097053	[79]	[91]	0	hSpCas9	negative selection	12001186
20933925	20933948	22	+	28162770	MONOMAC1	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.37391460914363306	[77]	[68]	-3	hSpCas9	negative selection	12001187
20934210	20934233	22	-	28162770	MONOMAC1	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.9951044086179388	[178]	[408]	8	hSpCas9	negative selection	12001188
20917964	20917987	22	-	28162770	MONOMAC1	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-1.7330897472997633	[86]	[29]	-8	hSpCas9	negative selection	12001189
20918024	20918047	22	-	28162770	MONOMAC1	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	0.0924697701354309	[26]	[32]	0	hSpCas9	negative selection	12001190
20917939	20917962	22	-	28162770	OCIAML2	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	0.2949049211208159	[4]	[33]	3	hSpCas9	negative selection	12170547
20918183	20918206	22	-	28162770	OCIAML2	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	0.7056929473983018	[24]	[225]	7	hSpCas9	negative selection	12170548
20918111	20918134	22	-	28162770	OCIAML2	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	0.44624485893897936	[95]	[724]	4	hSpCas9	negative selection	12170549
20918138	20918161	22	-	28162770	OCIAML2	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.0206182406568014	[52]	[297]	0	hSpCas9	negative selection	12170550
20933776	20933799	22	+	28162770	OCIAML2	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	0.6369852744048041	[91]	[792]	6	hSpCas9	negative selection	12170551
20918221	20918244	22	-	28162770	OCIAML2	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.29018251087841274	[17]	[121]	2	hSpCas9	negative selection	12170552
20933925	20933948	22	+	28162770	OCIAML2	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	0.810326488588895	[24]	[242]	7	hSpCas9	negative selection	12170553
20934210	20934233	22	-	28162770	OCIAML2	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.5728718133944256	[48]	[403]	5	hSpCas9	negative selection	12170554
20917964	20917987	22	-	28162770	OCIAML2	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	0.15872679483744834	[31]	[197]	1	hSpCas9	negative selection	12170555
20918024	20918047	22	-	28162770	OCIAML2	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-0.5037966891773606	[10]	[42]	-4	hSpCas9	negative selection	12170556
20917939	20917962	22	-	28162770	OCIAML3	viability	CGAGGAGTCGAACCTGGCGGAGG	CRKL	ENSG00000099942	1.4222941720049374	[10]	[88]	9	hSpCas9	negative selection	12339913
20918183	20918206	22	-	28162770	OCIAML3	viability	GGATCTTGTAAAACTCCAGCAGG	CRKL	ENSG00000099942	0.04984854945056144	[39]	[124]	0	hSpCas9	negative selection	12339914
20918111	20918134	22	-	28162770	OCIAML3	viability	GCAGCGAGTTGATGATGTAGTGG	CRKL	ENSG00000099942	1.3294203832810048	[132]	[1008]	9	hSpCas9	negative selection	12339915
20918138	20918161	22	-	28162770	OCIAML3	viability	GGTCCCCGATCTTAAAACGGCGG	CRKL	ENSG00000099942	0.25661473563761017	[60]	[219]	2	hSpCas9	negative selection	12339916
20933776	20933799	22	+	28162770	OCIAML3	viability	AAGGTATCCAAGCCCACCAATGG	CRKL	ENSG00000099942	-0.059969074765679364	[172]	[500]	0	hSpCas9	negative selection	12339917
20918221	20918244	22	-	28162770	OCIAML3	viability	GGGCGCAGGCTCGATGAGGGTGG	CRKL	ENSG00000099942	0.09787006431350503	[38]	[125]	0	hSpCas9	negative selection	12339918
20933925	20933948	22	+	28162770	OCIAML3	viability	TAGAGAAGCCTGAAGAACAGTGG	CRKL	ENSG00000099942	-0.8570420461579571	[47]	[79]	-6	hSpCas9	negative selection	12339919
20934210	20934233	22	-	28162770	OCIAML3	viability	GGCAGTCTTGTCATAAGCACAGG	CRKL	ENSG00000099942	0.8753092513759451	[118]	[658]	7	hSpCas9	negative selection	12339920
20917964	20917987	22	-	28162770	OCIAML3	viability	GCCCCATATACCAGGCGGAGCGG	CRKL	ENSG00000099942	-0.2272253096525405	[56]	[146]	-2	hSpCas9	negative selection	12339921
20918024	20918047	22	-	28162770	OCIAML3	viability	CGAGGAACATACCGTGGCGCTGG	CRKL	ENSG00000099942	-0.8055117455178751	[10]	[18]	-5	hSpCas9	negative selection	12339922