Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:867
• Symbol:Cbl
• Description:Cbl proto-oncogene

DataSource: http://genomecrispr.dkfz.de/#!/results/Cbl

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
119206564	119206587	11	+	26472758	Jiyoye	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-1.6098981318530683	[84]	[20]	-8	hSpCas9	negative selection	24021
119285258	119285281	11	-	26472758	Jiyoye	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.9415118091570617	[173]	[251]	6	hSpCas9	negative selection	24022
119271831	119271854	11	+	26472758	Jiyoye	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	-0.6517183075476951	[174]	[83]	-5	hSpCas9	negative selection	24023
119285047	119285070	11	-	26472758	Jiyoye	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	0.976541027176011	[61]	[91]	6	hSpCas9	negative selection	24024
119285361	119285384	11	-	26472758	Jiyoye	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	4.494638222756212	[0]	[16]	9	hSpCas9	negative selection	24025
119285377	119285400	11	-	26472758	Jiyoye	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.3746494779844256	[313]	[306]	3	hSpCas9	negative selection	24026
119232456	119232479	11	+	26472758	Jiyoye	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	0.09344776772037178	[306]	[246]	0	hSpCas9	negative selection	24027
119273918	119273941	11	-	26472758	Jiyoye	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	-0.2645919467525553	[136]	[85]	-2	hSpCas9	negative selection	24028
119278238	119278261	11	+	26472758	Jiyoye	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	1.142852279703507	[223]	[372]	7	hSpCas9	negative selection	24029
119284981	119285004	11	-	26472758	Jiyoye	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	0.23470818550110795	[70]	[62]	1	hSpCas9	negative selection	24030
119206564	119206587	11	+	26472758	KBM7	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-0.6594086093691418	[236,226]	[73,64]	-5	hSpCas9	negative selection	215139
119285258	119285281	11	-	26472758	KBM7	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.3526699007072695	[724,586]	[371,408]	4	hSpCas9	negative selection	215140
119271831	119271854	11	+	26472758	KBM7	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	-0.6671089985105166	[506,314]	[130,108]	-5	hSpCas9	negative selection	215141
119285047	119285070	11	-	26472758	KBM7	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.10046076333361686	[330,181]	[105,112]	-1	hSpCas9	negative selection	215142
119285361	119285384	11	-	26472758	KBM7	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	1.6536301689141606	[26,31]	[20,64]	9	hSpCas9	negative selection	215143
119285377	119285400	11	-	26472758	KBM7	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	-0.6402464717353976	[1440,982]	[419,306]	-5	hSpCas9	negative selection	215144
119232456	119232479	11	+	26472758	KBM7	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.47040370713208135	[1026,1125]	[409,331]	-4	hSpCas9	negative selection	215145
119273918	119273941	11	-	26472758	KBM7	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.461308323138234	[382,450]	[329,222]	5	hSpCas9	negative selection	215146
119278238	119278261	11	+	26472758	KBM7	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	-0.054440196789754536	[1230,940]	[564,417]	0	hSpCas9	negative selection	215147
119284981	119285004	11	-	26472758	KBM7	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	0.04900654075155564	[249,306]	[79,188]	0	hSpCas9	negative selection	215148
119206564	119206587	11	+	26472758	Raji	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-0.9223638080204526	[97]	[11]	-6	hSpCas9	negative selection	406257
119285258	119285281	11	-	26472758	Raji	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	1.0438805930674415	[417]	[199]	8	hSpCas9	negative selection	406258
119271831	119271854	11	+	26472758	Raji	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.5164962006953377	[243]	[80]	5	hSpCas9	negative selection	406259
119285047	119285070	11	-	26472758	Raji	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	1.882677248198905	[103]	[88]	9	hSpCas9	negative selection	406260
119285361	119285384	11	-	26472758	Raji	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	0.8372943720058552	[40]	[16]	7	hSpCas9	negative selection	406261
119285377	119285400	11	-	26472758	Raji	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.5224210346524432	[581]	[193]	5	hSpCas9	negative selection	406262
119232456	119232479	11	+	26472758	Raji	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	0.8178769181786149	[439]	[179]	7	hSpCas9	negative selection	406263
119273918	119273941	11	-	26472758	Raji	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.49915125532959626	[249]	[81]	5	hSpCas9	negative selection	406264
119278238	119278261	11	+	26472758	Raji	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.9841394349099735	[744]	[341]	8	hSpCas9	negative selection	406265
119284981	119285004	11	-	26472758	Raji	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	0.3132442328201591	[162]	[46]	3	hSpCas9	negative selection	406266
119206564	119206587	11	+	26472758	K562	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-2.160837750819811	[195]	[36]	-7	hSpCas9	negative selection	597375
119285258	119285281	11	-	26472758	K562	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.3516519509914745	[647]	[697]	2	hSpCas9	negative selection	597376
119271831	119271854	11	+	26472758	K562	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.43763801259787105	[313]	[358]	3	hSpCas9	negative selection	597377
119285047	119285070	11	-	26472758	K562	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	1.0678299959431239	[216]	[383]	8	hSpCas9	negative selection	597378
119285361	119285384	11	-	26472758	K562	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	-1.3015496414388457	[72]	[24]	-6	hSpCas9	negative selection	597379
119285377	119285400	11	-	26472758	K562	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	-0.32745207667635	[1096]	[737]	-2	hSpCas9	negative selection	597380
119232456	119232479	11	+	26472758	K562	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.2940358144303379	[991]	[682]	-2	hSpCas9	negative selection	597381
119273918	119273941	11	-	26472758	K562	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	-1.1131332769516367	[368]	[143]	-6	hSpCas9	negative selection	597382
119278238	119278261	11	+	26472758	K562	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.3353796654793516	[629]	[670]	2	hSpCas9	negative selection	597383
119284981	119285004	11	-	26472758	K562	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-0.49956729417753143	[205]	[122]	-3	hSpCas9	negative selection	597384
119206416	119206439	11	-	26627737	DLD1	viability	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	1.8076797268325469	[344]	[528,273,331]	9	hSpCas9	negative selection	777127
119232636	119232659	11	+	26627737	DLD1	viability	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.4269947206341423	[332]	[89,167,159]	4	hSpCas9	negative selection	777128
119273877	119273900	11	-	26627737	DLD1	viability	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.02266120758457224	[458]	[74,199,149]	0	hSpCas9	negative selection	777130
119276006	119276029	11	-	26627737	DLD1	viability	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.27324961837775014	[619]	[214,285,207]	3	hSpCas9	negative selection	777131
119277823	119277846	11	+	26627737	DLD1	viability	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.9491138454729543	[280]	[203,184,126]	8	hSpCas9	negative selection	777132
119278254	119278277	11	-	26627737	DLD1	viability	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	1.6175292080675208	[161]	[59,146,244]	9	hSpCas9	negative selection	777133
119206416	119206439	11	-	26627737	GBM cells	viability after 5 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.1611492250131547	[300]	[182,177]	2	hSpCas9	negative selection	859442
119232636	119232659	11	+	26627737	GBM cells	viability after 5 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.04196049265185037	[306]	[145,192]	0	hSpCas9	negative selection	859443
119273877	119273900	11	-	26627737	GBM cells	viability after 5 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.17034878755142827	[319]	[168,135]	-3	hSpCas9	negative selection	859445
119276006	119276029	11	-	26627737	GBM cells	viability after 5 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.12219057148174461	[232]	[130,140]	2	hSpCas9	negative selection	859446
119277823	119277846	11	+	26627737	GBM cells	viability after 5 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.19365714044681773	[224]	[136,138]	3	hSpCas9	negative selection	859447
119278254	119278277	11	-	26627737	GBM cells	viability after 5 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-0.16667446674189135	[44]	[25,16]	-3	hSpCas9	negative selection	859448
119206416	119206439	11	-	26627737	GBM cells	viability after 13 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.3719436335257241	[300]	[287,148]	5	hSpCas9	negative selection	941757
119232636	119232659	11	+	26627737	GBM cells	viability after 13 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.13856930476379775	[306]	[163,140]	-2	hSpCas9	negative selection	941758
119273877	119273900	11	-	26627737	GBM cells	viability after 13 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.7038210522811381	[319]	[126,89]	-7	hSpCas9	negative selection	941760
119276006	119276029	11	-	26627737	GBM cells	viability after 13 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.2454821247812391	[232]	[72,133]	-3	hSpCas9	negative selection	941761
119277823	119277846	11	+	26627737	GBM cells	viability after 13 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	-0.5948433764918536	[224]	[87,74]	-6	hSpCas9	negative selection	941762
119278254	119278277	11	-	26627737	GBM cells	viability after 13 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-2.0159744022237613	[44]	[10,1]	-9	hSpCas9	negative selection	941763
119206416	119206439	11	-	26627737	GBM cells	viability after 21 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.5415660852948403	[300]	[260,216]	5	hSpCas9	negative selection	1024072
119232636	119232659	11	+	26627737	GBM cells	viability after 21 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.30219899160638036	[306]	[128,140]	-3	hSpCas9	negative selection	1024073
119273877	119273900	11	-	26627737	GBM cells	viability after 21 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-1.0300425811774985	[319]	[81,87]	-7	hSpCas9	negative selection	1024075
119276006	119276029	11	-	26627737	GBM cells	viability after 21 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.5367777596050433	[232]	[92,81]	-5	hSpCas9	negative selection	1024076
119277823	119277846	11	+	26627737	GBM cells	viability after 21 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	-1.472659740744565	[224]	[42,44]	-8	hSpCas9	negative selection	1024077
119278254	119278277	11	-	26627737	GBM cells	viability after 21 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-4.611619796714017	[44]	[0,0]	-9	hSpCas9	negative selection	1024078
119206416	119206439	11	-	26627737	RPE1	viability after 9 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	1.1268400927593079	[895]	[526,722]	7	hSpCas9	negative selection	1106387
119232636	119232659	11	+	26627737	RPE1	viability after 9 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	4.175217993772593	[88]	[505,499]	9	hSpCas9	negative selection	1106388
119273877	119273900	11	-	26627737	RPE1	viability after 9 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.01914376825067618	[885]	[229,346]	0	hSpCas9	negative selection	1106390
119276006	119276029	11	-	26627737	RPE1	viability after 9 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.19685203453638916	[1081]	[374,192]	-1	hSpCas9	negative selection	1106391
119277823	119277846	11	+	26627737	RPE1	viability after 9 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	1.4676969423017199	[294]	[316,175]	8	hSpCas9	negative selection	1106392
119278254	119278277	11	-	26627737	RPE1	viability after 9 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-0.26220613350361033	[235]	[20,113]	-2	hSpCas9	negative selection	1106393
119206416	119206439	11	-	26627737	RPE1	viability after 12 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.9004293482820824	[895]	[392,508]	5	hSpCas9	negative selection	1188702
119232636	119232659	11	+	26627737	RPE1	viability after 12 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	4.7198476887448155	[88]	[701,553]	9	hSpCas9	negative selection	1188703
119273877	119273900	11	-	26627737	RPE1	viability after 12 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.2481071053195855	[885]	[163,238]	-2	hSpCas9	negative selection	1188705
119276006	119276029	11	-	26627737	RPE1	viability after 12 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.05630025358447771	[1081]	[315,240]	0	hSpCas9	negative selection	1188706
119277823	119277846	11	+	26627737	RPE1	viability after 12 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	2.3475053564244215	[294]	[517,281]	9	hSpCas9	negative selection	1188707
119278254	119278277	11	-	26627737	RPE1	viability after 12 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-2.090675092355162	[235]	[27,0]	-8	hSpCas9	negative selection	1188708
119206416	119206439	11	-	26627737	RPE1	viability after 15 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.7333722924344697	[895]	[399,441]	4	hSpCas9	negative selection	1271017
119232636	119232659	11	+	26627737	RPE1	viability after 15 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	4.363951202755715	[88]	[579,458]	9	hSpCas9	negative selection	1271018
119273877	119273900	11	-	26627737	RPE1	viability after 15 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.26143032576619685	[885]	[203,213]	-2	hSpCas9	negative selection	1271020
119276006	119276029	11	-	26627737	RPE1	viability after 15 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.5339573757779958	[1081]	[658,234]	3	hSpCas9	negative selection	1271021
119277823	119277846	11	+	26627737	RPE1	viability after 15 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	2.291218175085689	[294]	[663,161]	9	hSpCas9	negative selection	1271022
119278254	119278277	11	-	26627737	RPE1	viability after 15 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-0.9741995424797443	[235]	[34,32]	-6	hSpCas9	negative selection	1271023
119206416	119206439	11	-	26627737	RPE1	viability after 18 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	1.073593369137953	[895]	[316,713]	6	hSpCas9	negative selection	1353332
119232636	119232659	11	+	26627737	RPE1	viability after 18 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	4.935553873955126	[88]	[778,687]	9	hSpCas9	negative selection	1353333
119273877	119273900	11	-	26627737	RPE1	viability after 18 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.22782969937574116	[885]	[150,260]	-1	hSpCas9	negative selection	1353335
119276006	119276029	11	-	26627737	RPE1	viability after 18 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-1.2971262479606778	[1081]	[69,170]	-7	hSpCas9	negative selection	1353336
119277823	119277846	11	+	26627737	RPE1	viability after 18 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	3.0329860791559566	[294]	[1033,242]	9	hSpCas9	negative selection	1353337
119278254	119278277	11	-	26627737	RPE1	viability after 18 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-1.2222208816386093	[235]	[35,17]	-6	hSpCas9	negative selection	1353338
119206416	119206439	11	-	26627737	HeLa	viability after 8 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.3143872920963273	[303]	[322,168,44]	3	hSpCas9	negative selection	1435647
119232636	119232659	11	+	26627737	HeLa	viability after 8 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.5613075723222795	[357]	[70,56,175]	-5	hSpCas9	negative selection	1435648
119273877	119273900	11	-	26627737	HeLa	viability after 8 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	1.1060878740123214	[274]	[255,237,276]	8	hSpCas9	negative selection	1435650
119276006	119276029	11	-	26627737	HeLa	viability after 8 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.8614138288974256	[670]	[328,115,79]	-7	hSpCas9	negative selection	1435651
119277823	119277846	11	+	26627737	HeLa	viability after 8 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.09341162829517663	[304]	[261,87,103]	0	hSpCas9	negative selection	1435652
119278254	119278277	11	-	26627737	HeLa	viability after 8 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.19483293356217835	[101]	[165,8,5]	2	hSpCas9	negative selection	1435653
119206416	119206439	11	-	26627737	HeLa	viability after 12 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.9935588969987884	[303]	[208,242,297]	7	hSpCas9	negative selection	1517962
119232636	119232659	11	+	26627737	HeLa	viability after 12 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.12697722725422167	[357]	[129,175,95]	-1	hSpCas9	negative selection	1517963
119273877	119273900	11	-	26627737	HeLa	viability after 12 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.38530681362670227	[274]	[56,182,198]	3	hSpCas9	negative selection	1517965
119276006	119276029	11	-	26627737	HeLa	viability after 12 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.22505166931386344	[670]	[175,302,223]	-2	hSpCas9	negative selection	1517966
119277823	119277846	11	+	26627737	HeLa	viability after 12 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.5854296191806654	[304]	[279,179,110]	5	hSpCas9	negative selection	1517967
119278254	119278277	11	-	26627737	HeLa	viability after 12 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.6127933609224054	[101]	[16,139,26]	5	hSpCas9	negative selection	1517968
119206416	119206439	11	-	26627737	HeLa	viability after 15 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	1.282034781680225	[303]	[213,219,483]	8	hSpCas9	negative selection	1600277
119232636	119232659	11	+	26627737	HeLa	viability after 15 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.09734543876481416	[357]	[89,241,134]	0	hSpCas9	negative selection	1600278
119273877	119273900	11	-	26627737	HeLa	viability after 15 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.23362506231455094	[274]	[84,196,111]	2	hSpCas9	negative selection	1600280
119276006	119276029	11	-	26627737	HeLa	viability after 15 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.9024154641033227	[670]	[215,129,86]	-7	hSpCas9	negative selection	1600281
119277823	119277846	11	+	26627737	HeLa	viability after 15 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.5240931212173408	[304]	[193,83,263]	4	hSpCas9	negative selection	1600282
119278254	119278277	11	-	26627737	HeLa	viability after 15 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.4821466296275536	[101]	[125,38,3]	4	hSpCas9	negative selection	1600283
119206416	119206439	11	-	26627737	HeLa	viability after 18 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	1.2613849025372978	[303]	[132,184,483]	8	hSpCas9	negative selection	1682592
119232636	119232659	11	+	26627737	HeLa	viability after 18 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.07870754373168323	[357]	[55,200,134]	0	hSpCas9	negative selection	1682593
119273877	119273900	11	-	26627737	HeLa	viability after 18 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.20328152750338402	[274]	[50,163,111]	1	hSpCas9	negative selection	1682595
119276006	119276029	11	-	26627737	HeLa	viability after 18 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.9272096549751765	[670]	[146,98,86]	-7	hSpCas9	negative selection	1682596
119277823	119277846	11	+	26627737	HeLa	viability after 18 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.5190538194141622	[304]	[130,66,263]	4	hSpCas9	negative selection	1682597
119278254	119278277	11	-	26627737	HeLa	viability after 18 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.5027608359285161	[101]	[83,34,3]	4	hSpCas9	negative selection	1682598
119206416	119206439	11	-	26627737	HCT116	viability after 6 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.1862190385282695	[991]	[364,73]	1	hSpCas9	negative selection	1764907
119232636	119232659	11	+	26627737	HCT116	viability after 6 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.30941770280777364	[451]	[144,8]	-2	hSpCas9	negative selection	1764908
119273877	119273900	11	-	26627737	HCT116	viability after 6 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.12460953253606041	[710]	[39,166]	0	hSpCas9	negative selection	1764910
119276006	119276029	11	-	26627737	HCT116	viability after 6 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.5026379072079018	[1015]	[104,116]	-3	hSpCas9	negative selection	1764911
119277823	119277846	11	+	26627737	HCT116	viability after 6 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.2794487747690206	[748]	[256,79]	1	hSpCas9	negative selection	1764912
119278254	119278277	11	-	26627737	HCT116	viability after 6 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.19513912809510314	[39]	[12,3]	1	hSpCas9	negative selection	1764913
119206416	119206439	11	-	26627737	HCT116	viability after 8 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	-0.04772016621776548	[409]	[198,207,247]	0	hSpCas9	negative selection	1847222
119232636	119232659	11	+	26627737	HCT116	viability after 8 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.04168974754008217	[359]	[292,180,106]	0	hSpCas9	negative selection	1847223
119273877	119273900	11	-	26627737	HCT116	viability after 8 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.2631466747352328	[299]	[170,118,123]	-3	hSpCas9	negative selection	1847225
119276006	119276029	11	-	26627737	HCT116	viability after 8 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.17792400716278878	[348]	[144,149,213]	-2	hSpCas9	negative selection	1847226
119277823	119277846	11	+	26627737	HCT116	viability after 8 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.3526909192976432	[218]	[154,210,96]	4	hSpCas9	negative selection	1847227
119278254	119278277	11	-	26627737	HCT116	viability after 8 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-0.7772830112256608	[98]	[3,59,30]	-7	hSpCas9	negative selection	1847228
119206416	119206439	11	-	26627737	HCT116	viability after 9 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	-1.7699828551002827	[991]	[118,44]	-8	hSpCas9	negative selection	1929537
119232636	119232659	11	+	26627737	HCT116	viability after 9 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.6411960741569086	[451]	[371,42]	4	hSpCas9	negative selection	1929538
119273877	119273900	11	-	26627737	HCT116	viability after 9 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.1506574647377362	[710]	[50,336]	1	hSpCas9	negative selection	1929540
119276006	119276029	11	-	26627737	HCT116	viability after 9 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.6163096345734937	[1015]	[243,123]	-4	hSpCas9	negative selection	1929541
119277823	119277846	11	+	26627737	HCT116	viability after 9 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	-0.16809866613888452	[748]	[301,79]	-1	hSpCas9	negative selection	1929542
119278254	119278277	11	-	26627737	HCT116	viability after 9 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	3.4303589484699475	[39]	[46,168]	9	hSpCas9	negative selection	1929543
119206416	119206439	11	-	26627737	HCT116	viability after 12 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.08157906987712005	[409]	[179,383,127]	0	hSpCas9	negative selection	2011852
119232636	119232659	11	+	26627737	HCT116	viability after 12 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.43879270225764333	[359]	[125,142,150]	-5	hSpCas9	negative selection	2011853
119273877	119273900	11	-	26627737	HCT116	viability after 12 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.32934558501672173	[299]	[184,180,228]	3	hSpCas9	negative selection	2011855
119276006	119276029	11	-	26627737	HCT116	viability after 12 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.19499118673770374	[348]	[139,141,199]	-2	hSpCas9	negative selection	2011856
119277823	119277846	11	+	26627737	HCT116	viability after 12 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.5330300014983244	[218]	[134,233,134]	5	hSpCas9	negative selection	2011857
119278254	119278277	11	-	26627737	HCT116	viability after 12 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.04724571792239951	[98]	[19,84,59]	0	hSpCas9	negative selection	2011858
119206416	119206439	11	-	26627737	HCT116	viability after 15 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	-0.10288882916568187	[409]	[172,331,147]	-1	hSpCas9	negative selection	2094167
119232636	119232659	11	+	26627737	HCT116	viability after 15 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.14541832903818858	[359]	[218,102,241]	-1	hSpCas9	negative selection	2094168
119273877	119273900	11	-	26627737	HCT116	viability after 15 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.3177149192459844	[299]	[195,237,207]	3	hSpCas9	negative selection	2094170
119276006	119276029	11	-	26627737	HCT116	viability after 15 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	-0.5973733800477921	[348]	[108,105,178]	-6	hSpCas9	negative selection	2094171
119277823	119277846	11	+	26627737	HCT116	viability after 15 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.8881038012673497	[218]	[289,242,172]	7	hSpCas9	negative selection	2094172
119278254	119278277	11	-	26627737	HCT116	viability after 15 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-0.5342981499484571	[98]	[0,62,48]	-5	hSpCas9	negative selection	2094173
119206416	119206439	11	-	26627737	HCT116	viability after 18 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	-0.4675681609239648	[409]	[63,278,74]	-4	hSpCas9	negative selection	2176482
119232636	119232659	11	+	26627737	HCT116	viability after 18 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.7076627449497073	[359]	[127,60,134]	-6	hSpCas9	negative selection	2176483
119273877	119273900	11	-	26627737	HCT116	viability after 18 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.5848219054062606	[299]	[186,277,181]	5	hSpCas9	negative selection	2176485
119276006	119276029	11	-	26627737	HCT116	viability after 18 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.018790175567372752	[348]	[129,168,215]	0	hSpCas9	negative selection	2176486
119277823	119277846	11	+	26627737	HCT116	viability after 18 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.8020422569532493	[218]	[229,189,130]	6	hSpCas9	negative selection	2176487
119278254	119278277	11	-	26627737	HCT116	viability after 18 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-1.2254880482747852	[98]	[12,26,20]	-8	hSpCas9	negative selection	2176488
119206403	119206426	11	+	24336569	HL60	viability	GACCCTGCCCAGGCCATGGCCGG	CBL	ENSG00000110395	0.05539213602087101	[607]	[1336]	0	hSpCas9	negative selection	2254586
119206416	119206439	11	-	24336569	HL60	viability	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	1.0651800769775075	[235]	[1044]	7	hSpCas9	negative selection	2254587
119206422	119206445	11	-	24336569	HL60	viability	AGAGCTCTTCTTCACGTTGCCGG	CBL	ENSG00000110395	0.13347921089508208	[637]	[1480]	1	hSpCas9	negative selection	2254588
119206475	119206498	11	+	24336569	HL60	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.06457232123012313	[933]	[1889]	0	hSpCas9	negative selection	2254589
119206486	119206509	11	+	24336569	HL60	viability	TGGCCTGATTGGGCTCATGAAGG	CBL	ENSG00000110395	-0.6781627094010213	[647]	[856]	-6	hSpCas9	negative selection	2254590
119206512	119206535	11	-	24336569	HL60	viability	GTGGTGGTGGTGCGGCTGGAAGG	CBL	ENSG00000110395	-0.5088324018184596	[469]	[698]	-4	hSpCas9	negative selection	2254591
119206564	119206587	11	+	24336569	HL60	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-0.16372178274797522	[829]	[1567]	-1	hSpCas9	negative selection	2254592
119206575	119206598	11	+	24336569	HL60	viability	AGAAGATGGTGGAGAAGTGCTGG	CBL	ENSG00000110395	-0.18462716968430076	[767]	[1429]	-2	hSpCas9	negative selection	2254593
119206585	119206608	11	+	24336569	HL60	viability	GGAGAAGTGCTGGAAGCTCATGG	CBL	ENSG00000110395	0.23630303788332335	[624]	[1557]	2	hSpCas9	negative selection	2254594
119232434	119232457	11	+	24336569	HL60	viability	TTCATTTGTTGCAGGTGGTGCGG	CBL	ENSG00000110395	-0.22027297770077148	[773]	[1405]	-2	hSpCas9	negative selection	2254595
119206403	119206426	11	+	24336569	KBM7	viability	GACCCTGCCCAGGCCATGGCCGG	CBL	ENSG00000110395	-0.45066078200151866	[702]	[1402]	-4	hSpCas9	negative selection	2321763
119206416	119206439	11	-	24336569	KBM7	viability	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.3377097841551376	[319]	[1102]	3	hSpCas9	negative selection	2321764
119206422	119206445	11	-	24336569	KBM7	viability	AGAGCTCTTCTTCACGTTGCCGG	CBL	ENSG00000110395	0.2763935591723633	[289]	[957]	2	hSpCas9	negative selection	2321765
119206475	119206498	11	+	24336569	KBM7	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.719727822247293	[428]	[1926]	6	hSpCas9	negative selection	2321766
119206486	119206509	11	+	24336569	KBM7	viability	TGGCCTGATTGGGCTCATGAAGG	CBL	ENSG00000110395	0.32831476385774216	[350]	[1201]	3	hSpCas9	negative selection	2321767
119206512	119206535	11	-	24336569	KBM7	viability	GTGGTGGTGGTGCGGCTGGAAGG	CBL	ENSG00000110395	-2.536955003879575	[565]	[265]	-8	hSpCas9	negative selection	2321768
119206564	119206587	11	+	24336569	KBM7	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-1.445862723959861	[839]	[840]	-7	hSpCas9	negative selection	2321769
119206575	119206598	11	+	24336569	KBM7	viability	AGAAGATGGTGGAGAAGTGCTGG	CBL	ENSG00000110395	0.9940191290010962	[295]	[1607]	8	hSpCas9	negative selection	2321770
119206585	119206608	11	+	24336569	KBM7	viability	GGAGAAGTGCTGGAAGCTCATGG	CBL	ENSG00000110395	-0.1658709499143048	[370]	[901]	-1	hSpCas9	negative selection	2321771
119232434	119232457	11	+	24336569	KBM7	viability	TTCATTTGTTGCAGGTGGTGCGG	CBL	ENSG00000110395	0.6638420861195404	[410]	[1775]	6	hSpCas9	negative selection	2321772
119256330	119256353	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTAGCGG	CBL	ENSG00000110395	-0.9180937029961482	[133,53]	[15,3]	-5	dCas9-VP64	positive selection	2404994
119212799	119212822	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGCAGTTTGAGACCAGCCTGG	CBL	ENSG00000110395	-2.729845497757659	[196,428]	[6,13]	-9	dCas9-VP64	positive selection	2412719
119239030	119239053	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTTGCAGTGAGCTGAGATTGAG	CBL	ENSG00000110395	0.09247990967442199	[398,266]	[75,78]	0	dCas9-VP64	positive selection	2414635
119206158	119206181	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTAAGCCGGTCCGCCTCCGGG	CBL	ENSG00000110395	1.5934861518705525	[65,81]	[29,69]	6	dCas9-VP64	positive selection	2437385
119206086	119206109	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCTCGAAGCCGGTGGCCCGGG	CBL	ENSG00000110395	-2.779178279860656	[40,223]	[3,3]	-9	dCas9-VP64	positive selection	2437386
119206104	119206127	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACTGGGCAGCGACGATCCCCGG	CBL	ENSG00000110395	-0.4864875570362106	[20,52]	[2,7]	-2	dCas9-VP64	positive selection	2437387
119233299	119233322	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGTGCGATCTCAG	CBL	ENSG00000110395	4.070372888524917	[22,16]	[45,107]	9	dCas9-VP64	positive selection	2443404
119246524	119246547	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCGCAACCTCCGCCTCCTGG	CBL	ENSG00000110395	-0.9705266312095737	[543,439]	[39,70]	-6	dCas9-VP64	positive selection	2469234
119256330	119256353	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTAGCGG	CBL	ENSG00000110395	0.01566490298595924	[8,84]	[11,17]	0	dCas9-VP64	positive selection	2500249
119212799	119212822	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGCAGTTTGAGACCAGCCTGG	CBL	ENSG00000110395	-1.135721094933603	[195,105]	[22,20]	-9	dCas9-VP64	positive selection	2507974
119239030	119239053	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTTGCAGTGAGCTGAGATTGAG	CBL	ENSG00000110395	-0.8679421240235777	[178,269]	[31,46]	-7	dCas9-VP64	positive selection	2509890
119206158	119206181	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTAAGCCGGTCCGCCTCCGGG	CBL	ENSG00000110395	0.5038205623063764	[39,123]	[47,27]	4	dCas9-VP64	positive selection	2532640
119206086	119206109	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCTCGAAGCCGGTGGCCCGGG	CBL	ENSG00000110395	1.1159809211838767	[48,100]	[17,84]	7	dCas9-VP64	positive selection	2532641
119206104	119206127	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACTGGGCAGCGACGATCCCCGG	CBL	ENSG00000110395	-1.0116177804854813	[45,87]	[11,8]	-8	dCas9-VP64	positive selection	2532642
119233299	119233322	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGTGCGATCTCAG	CBL	ENSG00000110395	1.6841538162097147	[121,126]	[189,75]	8	dCas9-VP64	positive selection	2538659
119246524	119246547	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCGCAACCTCCGCCTCCTGG	CBL	ENSG00000110395	0.25678800348412345	[582,649]	[296,187]	2	dCas9-VP64	positive selection	2564489
119271785	119271808	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAAAAGGAATCTTTCCAAGTGG	CBL	ENSG00000110395	0.194176130032729	[4,4]	[5,3]	4	hSpCas9	positive selection	2976522
119232524	119232547	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATAGTACGGAGATGCTGGTAGG	CBL	ENSG00000110395	-0.3435410309097604	[3,3]	[3,0]	-5	hSpCas9	positive selection	2976523
119271785	119271808	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAAAAGGAATCTTTCCAAGTGG	CBL	ENSG00000110395	0.5360327802828277	[4,4]	[4,5]	8	hSpCas9	positive selection	3044380
119232524	119232547	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATAGTACGGAGATGCTGGTAGG	CBL	ENSG00000110395	0.47424760172209063	[3,3]	[4,2]	7	hSpCas9	positive selection	3044381
119206489	119206512		-	24336571	A375	resistance to PLX after 7 days	CGTCCTTCATGAGCCCAATCAGG	CBL	ENSG00000110395	0.3109830553512465	[18,17]	[23,22]	8	hSpCas9	positive selection	3160849
119232469	119232492		-	24336571	A375	resistance to PLX after 7 days	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	-0.029060062392295333	[11,10]	[10,10]	-1	hSpCas9	positive selection	3160850
119232633	119232656		+	24336571	A375	resistance to PLX after 7 days	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.04845009830661584	[5,5]	[5,4]	-1	hSpCas9	positive selection	3160851
119206475	119206498		+	24336571	A375	resistance to PLX after 7 days	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.030413578047335466	[21,18]	[21,18]	1	hSpCas9	positive selection	3160852
119206489	119206512		-	24336571	A375	resistance to PLX after 14 days	CGTCCTTCATGAGCCCAATCAGG	CBL	ENSG00000110395	1.3777339856519308	[14,23]	[22,24]	8	hSpCas9	positive selection	3218642
119232469	119232492		-	24336571	A375	resistance to PLX after 14 days	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.02318770445394358	[14,14]	[4,7]	0	hSpCas9	positive selection	3218643
119232633	119232656		+	24336571	A375	resistance to PLX after 14 days	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.34324860040453364	[6,4]	[1,1]	-4	hSpCas9	positive selection	3218644
119206475	119206498		+	24336571	A375	resistance to PLX after 14 days	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.4035390829889177	[19,21]	[6,6]	-5	hSpCas9	positive selection	3218645
119206489	119206512		-	24336571	A375	viability after 7 days	CGTCCTTCATGAGCCCAATCAGG	CBL	ENSG00000110395	0.48661401797657916	[13]	[18,17]	7	hSpCas9	negative selection	3276435
119232469	119232492		-	24336571	A375	viability after 7 days	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.09672138767847935	[10]	[11,10]	1	hSpCas9	negative selection	3276436
119232633	119232656		+	24336571	A375	viability after 7 days	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.7050424758006801	[10]	[5,5]	-7	hSpCas9	negative selection	3276437
119206475	119206498		+	24336571	A375	viability after 7 days	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.6281520720679425	[13]	[21,18]	8	hSpCas9	negative selection	3276438
119206489	119206512		-	24336571	A375	viability after 14 days	CGTCCTTCATGAGCCCAATCAGG	CBL	ENSG00000110395	0.559491042242792	[13]	[14,23]	7	hSpCas9	negative selection	3334228
119232469	119232492		-	24336571	A375	viability after 14 days	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.4850145882064714	[10]	[14,14]	6	hSpCas9	negative selection	3334229
119232633	119232656		+	24336571	A375	viability after 14 days	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.734750630045482	[10]	[6,4]	-7	hSpCas9	negative selection	3334230
119206475	119206498		+	24336571	A375	viability after 14 days	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.7109903147591445	[13]	[19,21]	8	hSpCas9	negative selection	3334231
119274003	119274026	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.1131011853529372	[134,147]	[0,0]	0	hSpCas9	positive selection	3341205
119232469	119232492	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	-0.20156954749622943	[165,185]	[0,0]	-1	hSpCas9	positive selection	3341206
119206559	119206582	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	-1.0160275559811942	[294,323]	[0,0]	-6	hSpCas9	positive selection	3341207
119206475	119206498	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.10899600279998067	[164,164]	[0,0]	0	hSpCas9	positive selection	3360448
119273861	119273884	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	1.257326211445835	[63,63]	[0,0]	5	hSpCas9	positive selection	3360449
119232633	119232656	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.12637808102821713	[166,166]	[0,0]	0	hSpCas9	positive selection	3360450
119271784	119271807	11	+	26780180	HT29	viability (Avana library 4 designs)	CTAAAAGGAATCTTTCCAAGTGG	CBL	ENSG00000110395	0.0238185759799269	[]	[]	0	hSpCas9	negative selection	3412803
119232524	119232547	11	-	26780180	HT29	viability (Avana library 4 designs)	GATAGTACGGAGATGCTGGTAGG	CBL	ENSG00000110395	1.57356153516889	[]	[]	6	hSpCas9	negative selection	3412804
119278573	119278596	11	+	26780180	HT29	viability (Avana library 4 designs)	GTAGATCCGTTTGATCCTAGAGG	CBL	ENSG00000110395	0.624753416475562	[]	[]	2	hSpCas9	negative selection	3412805
119278633	119278656	11	-	26780180	HT29	viability (Avana library 4 designs)	TCATCATCATAATTTGGGGAGGG	CBL	ENSG00000110395	0.202314542236657	[]	[]	0	hSpCas9	negative selection	3412806
119278633	119278656	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATCATCATAATTTGGGGAGGG	CBL	ENSG00000110395	-5.60949671033387	[]	[]	-6	hSpCas9	negative selection	3488451
119278573	119278596	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATCCGTTTGATCCTAGAGG	CBL	ENSG00000110395	-2.67424512092121	[]	[]	-3	hSpCas9	negative selection	3488452
119232524	119232547	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATAGTACGGAGATGCTGGTAGG	CBL	ENSG00000110395	4.6067561867415	[]	[]	7	hSpCas9	negative selection	3488453
119271784	119271807	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAAAAGGAATCTTTCCAAGTGG	CBL	ENSG00000110395	-6.9714949932444	[]	[]	-6	hSpCas9	negative selection	3488454
119278633	119278656	11	-	26780180	A375	viability (Avana lentiGuide)	TCATCATCATAATTTGGGGAGGG	CBL	ENSG00000110395	1.56930211320997	[]	[]	1	hSpCas9	negative selection	3597110
119278573	119278596	11	+	26780180	A375	viability (Avana lentiGuide)	GTAGATCCGTTTGATCCTAGAGG	CBL	ENSG00000110395	-0.571303652526717	[]	[]	-1	hSpCas9	negative selection	3597111
119232524	119232547	11	-	26780180	A375	viability (Avana lentiGuide)	GATAGTACGGAGATGCTGGTAGG	CBL	ENSG00000110395	4.6677693823639	[]	[]	4	hSpCas9	negative selection	3597112
119271784	119271807	11	+	26780180	A375	viability (Avana lentiGuide)	CTAAAAGGAATCTTTCCAAGTGG	CBL	ENSG00000110395	0.549480203979034	[]	[]	0	hSpCas9	negative selection	3597113
119278633	119278656	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATCATCATAATTTGGGGAGGG	CBL	ENSG00000110395	-0.15512696814109186	[6]	[5,5]	-3	hSpCas9	positive selection	3705769
119278573	119278596	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATCCGTTTGATCCTAGAGG	CBL	ENSG00000110395	-0.09640136731723087	[7]	[6,6]	-2	hSpCas9	positive selection	3705770
119232524	119232547	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATAGTACGGAGATGCTGGTAGG	CBL	ENSG00000110395	0.05503661446301284	[5]	[5,4]	1	hSpCas9	positive selection	3705771
119271784	119271807	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAAAAGGAATCTTTCCAAGTGG	CBL	ENSG00000110395	-0.27488356118584356	[7]	[5,5]	-4	hSpCas9	positive selection	3705772
119278633	119278656	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATCATCATAATTTGGGGAGGG	CBL	ENSG00000110395	-0.0751983321695068	[5]	[5,3]	-1	hSpCas9	positive selection	3814376
119278573	119278596	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATCCGTTTGATCCTAGAGG	CBL	ENSG00000110395	-0.22273433264617995	[5]	[4,3]	-3	hSpCas9	positive selection	3814377
119232524	119232547	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATAGTACGGAGATGCTGGTAGG	CBL	ENSG00000110395	0.11828574274622625	[5]	[5,4]	2	hSpCas9	positive selection	3814378
119271784	119271807	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAAAAGGAATCTTTCCAAGTGG	CBL	ENSG00000110395	0.28435316987576054	[6]	[5,6]	7	hSpCas9	positive selection	3814379
119206559	119206582	11	-	26780180	A375	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	1.40159813962498	[]	[]	7	hSpCas9	negative selection	3922683
119274003	119274026	11	+	26780180	A375	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.487999101273321	[]	[]	1	hSpCas9	negative selection	3922684
119232469	119232492	11	-	26780180	A375	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.171060826073553	[]	[]	0	hSpCas9	negative selection	3922685
119232633	119232656	11	+	26780180	A375	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.879682220870847	[]	[]	3	hSpCas9	negative selection	3922686
119273861	119273884	11	+	26780180	A375	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.893106062859534	[]	[]	4	hSpCas9	negative selection	3922687
119206475	119206498	11	+	26780180	A375	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	1.2735225141475	[]	[]	7	hSpCas9	negative selection	3922688
119206559	119206582	11	-	26780180	HT29	viability (GeCKOv2 library)	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.793756112834559	[]	[]	3	hSpCas9	negative selection	4030649
119274003	119274026	11	+	26780180	HT29	viability (GeCKOv2 library)	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.622929471919139	[]	[]	2	hSpCas9	negative selection	4030650
119232469	119232492	11	-	26780180	HT29	viability (GeCKOv2 library)	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.383432259511981	[]	[]	1	hSpCas9	negative selection	4030651
119232633	119232656	11	+	26780180	HT29	viability (GeCKOv2 library)	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.531420730011287	[]	[]	1	hSpCas9	negative selection	4030652
119273861	119273884	11	+	26780180	HT29	viability (GeCKOv2 library)	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	1.62520755321434	[]	[]	8	hSpCas9	negative selection	4030653
119206475	119206498	11	+	26780180	HT29	viability (GeCKOv2 library)	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	1.26450517014502	[]	[]	6	hSpCas9	negative selection	4030654
119206489	119206512	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCCTTCATGAGCCCAATCAGG	CBL	ENSG00000110395	0.49935501982408814	[3]	[2,4]	9	hSpCas9	positive selection	4188943
119232469	119232492	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.13317501127327258	[3]	[2,2]	3	hSpCas9	positive selection	4188944
119232633	119232656	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.4470349930881848	[3]	[1,0]	-8	hSpCas9	positive selection	4188945
119206475	119206498	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.08871086715969194	[3]	[2,2]	2	hSpCas9	positive selection	4188946
119206489	119206512	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCCTTCATGAGCCCAATCAGG	CBL	ENSG00000110395	0.7060176926580426	[3]	[0,0,1,3]	4	hSpCas9	positive selection	4252965
119232469	119232492	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	-0.47881029928023966	[4]	[0,2,1,0]	-6	hSpCas9	positive selection	4252966
119232633	119232656	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.1356153509780363	[3]	[3,0,0,0]	-2	hSpCas9	positive selection	4252967
119206475	119206498	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	1.1457851988661336	[3]	[2,2,2,3]	8	hSpCas9	positive selection	4252968
119274003	119274026	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	-0.014169276485856502	[2]	[2,1]	0	hSpCas9	positive selection	4261093
119232469	119232492	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.6692987721892413	[2]	[3,3]	9	hSpCas9	positive selection	4261094
119206559	119206582	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	-0.02158619096938541	[4]	[4,2]	0	hSpCas9	positive selection	4261095
119206475	119206498	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.18913975284841972	[2]	[2,2]	4	hSpCas9	positive selection	4325371
119273861	119273884	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.018168925964478944	[2]	[1,1]	0	hSpCas9	positive selection	4325372
119232633	119232656	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.6085693856538944	[2]	[3,3]	9	hSpCas9	positive selection	4325373
119206552	119206574	11	-	27760321	OCIAML3	viability	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.04273723544665098	[880,705]	[602,677]	0	hSpCas9	negative selection	4385939
119232493	119232515	11	-	27760321	OCIAML3	viability	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	1.281205276878572	[100,55]	[74,238]	9	hSpCas9	negative selection	4385940
119273878	119273900	11	+	27760321	OCIAML3	viability	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.7674920977205406	[458,390]	[487,662]	8	hSpCas9	negative selection	4385941
119273954	119273976	11	-	27760321	OCIAML3	viability	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	0.6911171671174987	[169,118]	[113,266]	7	hSpCas9	negative selection	4385942
119278564	119278586	11	-	27760321	OCIAML3	viability	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.4302085577823652	[548,454]	[517,537]	5	hSpCas9	negative selection	4385943
119206552	119206574	11	-	27760321	OCIAML2	viability	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.26235248227670016	[880,705]	[714,831]	3	hSpCas9	negative selection	4469402
119232493	119232515	11	-	27760321	OCIAML2	viability	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	-0.29071376421414197	[100,55]	[49,51]	-4	hSpCas9	negative selection	4469403
119273878	119273900	11	+	27760321	OCIAML2	viability	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.5808455442484695	[458,390]	[389,673]	7	hSpCas9	negative selection	4469404
119273954	119273976	11	-	27760321	OCIAML2	viability	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	0.1057638805448593	[169,118]	[110,141]	1	hSpCas9	negative selection	4469405
119278564	119278586	11	-	27760321	OCIAML2	viability	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.17969577911747672	[548,454]	[403,528]	2	hSpCas9	negative selection	4469406
119206552	119206574	11	-	27760321	MV411	viability	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.5403618301401446	[880,705]	[448,1219]	4	hSpCas9	negative selection	4552865
119232493	119232515	11	-	27760321	MV411	viability	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	1.3158065520362614	[100,55]	[61,222]	8	hSpCas9	negative selection	4552866
119273878	119273900	11	+	27760321	MV411	viability	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.49360612871526394	[458,390]	[365,434]	3	hSpCas9	negative selection	4552867
119273954	119273976	11	-	27760321	MV411	viability	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	-0.5065756273413777	[169,118]	[27,123]	-4	hSpCas9	negative selection	4552868
119278564	119278586	11	-	27760321	MV411	viability	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	-1.3384294977667572	[548,454]	[159,85]	-7	hSpCas9	negative selection	4552869
119206552	119206574	11	-	27760321	HL60	viability	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.6040274644322728	[880,705]	[897,1065]	7	hSpCas9	negative selection	4636328
119232493	119232515	11	-	27760321	HL60	viability	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	0.06852430985303837	[100,55]	[61,69]	0	hSpCas9	negative selection	4636329
119273878	119273900	11	+	27760321	HL60	viability	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.17648979675154308	[458,390]	[475,300]	2	hSpCas9	negative selection	4636330
119273954	119273976	11	-	27760321	HL60	viability	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	-0.930892592260566	[169,118]	[51,70]	-7	hSpCas9	negative selection	4636331
119278564	119278586	11	-	27760321	HL60	viability	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.5031618577380619	[548,454]	[599,555]	6	hSpCas9	negative selection	4636332
119206552	119206574	11	-	27760321	HT1080	viability	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	-1.5424460163659879	[705,550]	[84,86]	-5	hSpCas9	negative selection	4719791
119232493	119232515	11	-	27760321	HT1080	viability	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	2.317483671052953	[55,43]	[42,160]	9	hSpCas9	negative selection	4719792
119273878	119273900	11	+	27760321	HT1080	viability	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.05453154444376595	[390,304]	[58,236]	0	hSpCas9	negative selection	4719793
119273954	119273976	11	-	27760321	HT1080	viability	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	-0.12140967861045504	[118,92]	[13,65]	0	hSpCas9	negative selection	4719794
119278564	119278586	11	-	27760321	HT1080	viability	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	1.0861224239180467	[454,354]	[479,191]	6	hSpCas9	negative selection	4719795
119206552	119206574	11	-	27760321	HT29	viability after 7 days	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.3947779994080358	[705,550]	[845,1029,1271]	6	hSpCas9	negative selection	4803254
119232493	119232515	11	-	27760321	HT29	viability after 7 days	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	0.45096294319288566	[55,43]	[113,54,97]	7	hSpCas9	negative selection	4803255
119273878	119273900	11	+	27760321	HT29	viability after 7 days	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	-0.14175030396307525	[390,304]	[513,422,297]	-2	hSpCas9	negative selection	4803256
119273954	119273976	11	-	27760321	HT29	viability after 7 days	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	0.025949232326936578	[118,92]	[157,94,164]	0	hSpCas9	negative selection	4803257
119278564	119278586	11	-	27760321	HT29	viability after 7 days	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.748499438505508	[454,354]	[934,766,927]	9	hSpCas9	negative selection	4803258
119206552	119206574	11	-	27760321	HT29	viability after 25 days	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.16533767066406457	[705,550]	[721,698,1021]	1	hSpCas9	negative selection	4886717
119232493	119232515	11	-	27760321	HT29	viability after 25 days	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	0.8232253358290009	[55,43]	[119,98,80]	8	hSpCas9	negative selection	4886718
119273878	119273900	11	+	27760321	HT29	viability after 25 days	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.6239839279446442	[390,304]	[498,783,555]	7	hSpCas9	negative selection	4886719
119273954	119273976	11	-	27760321	HT29	viability after 25 days	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	1.1858890184339692	[118,92]	[214,203,426]	9	hSpCas9	negative selection	4886720
119278564	119278586	11	-	27760321	HT29	viability after 25 days	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.254308648999638	[454,354]	[485,728,431]	2	hSpCas9	negative selection	4886721
119206552	119206574	11	-	27760321	HT29	viability after 22 days	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.049894566919508776	[705,550]	[605,729,925]	0	hSpCas9	negative selection	4970180
119232493	119232515	11	-	27760321	HT29	viability after 22 days	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	0.854218271139896	[55,43]	[112,30,169]	8	hSpCas9	negative selection	4970181
119273878	119273900	11	+	27760321	HT29	viability after 22 days	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.2332690741018865	[390,304]	[376,701,340]	2	hSpCas9	negative selection	4970182
119273954	119273976	11	-	27760321	HT29	viability after 22 days	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	1.2008159391659396	[118,92]	[254,82,509]	9	hSpCas9	negative selection	4970183
119278564	119278586	11	-	27760321	HT29	viability after 22 days	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.5495695906936304	[454,354]	[841,475,733]	6	hSpCas9	negative selection	4970184
119206552	119206574	11	-	27760321	HT29	viability after 19 days	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.15596249561217657	[705,550]	[1034,441,943]	1	hSpCas9	negative selection	5053643
119232493	119232515	11	-	27760321	HT29	viability after 19 days	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	0.11825348321216422	[55,43]	[148,1,44]	1	hSpCas9	negative selection	5053644
119273878	119273900	11	+	27760321	HT29	viability after 19 days	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.43061762521580316	[390,304]	[505,678,424]	4	hSpCas9	negative selection	5053645
119273954	119273976	11	-	27760321	HT29	viability after 19 days	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	1.1670692608369282	[118,92]	[506,84,249]	9	hSpCas9	negative selection	5053646
119278564	119278586	11	-	27760321	HT29	viability after 19 days	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.8723872780544485	[454,354]	[755,537,1224]	8	hSpCas9	negative selection	5053647
119206552	119206574	11	-	27760321	HT29	viability after 16 days	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.5142955757379142	[705,550]	[998,1131,877]	6	hSpCas9	negative selection	5137106
119232493	119232515	11	-	27760321	HT29	viability after 16 days	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	1.189190730785135	[55,43]	[144,144,93]	9	hSpCas9	negative selection	5137107
119273878	119273900	11	+	27760321	HT29	viability after 16 days	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.3786331692296303	[390,304]	[502,702,306]	4	hSpCas9	negative selection	5137108
119273954	119273976	11	-	27760321	HT29	viability after 16 days	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	1.2734690344500237	[118,92]	[357,126,385]	9	hSpCas9	negative selection	5137109
119278564	119278586	11	-	27760321	HT29	viability after 16 days	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.4427222772036985	[454,354]	[705,690,456]	5	hSpCas9	negative selection	5137110
119206552	119206574	11	-	27760321	HT29	viability after 13 days	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.47571403455568695	[705,550]	[943,1070,1025]	6	hSpCas9	negative selection	5220569
119232493	119232515	11	-	27760321	HT29	viability after 13 days	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	0.4352029594280764	[55,43]	[37,76,117]	5	hSpCas9	negative selection	5220570
119273878	119273900	11	+	27760321	HT29	viability after 13 days	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	0.48462247639200384	[390,304]	[526,745,429]	6	hSpCas9	negative selection	5220571
119273954	119273976	11	-	27760321	HT29	viability after 13 days	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	0.5309162642194944	[118,92]	[60,135,326]	6	hSpCas9	negative selection	5220572
119278564	119278586	11	-	27760321	HT29	viability after 13 days	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.4185104807320714	[454,354]	[776,590,521]	5	hSpCas9	negative selection	5220573
119206552	119206574	11	-	27760321	HT29	viability after 10 days	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	0.6660316662151735	[705,550]	[1026,1279,1424]	8	hSpCas9	negative selection	5304032
119232493	119232515	11	-	27760321	HT29	viability after 10 days	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	1.3032555919054327	[55,43]	[26,243,192]	9	hSpCas9	negative selection	5304033
119273878	119273900	11	+	27760321	HT29	viability after 10 days	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	-0.02524185619432741	[390,304]	[501,417,361]	0	hSpCas9	negative selection	5304034
119273954	119273976	11	-	27760321	HT29	viability after 10 days	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	0.5434608877064846	[118,92]	[438,68,69]	7	hSpCas9	negative selection	5304035
119278564	119278586	11	-	27760321	HT29	viability after 10 days	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	0.3749552158441207	[454,354]	[604,856,513]	5	hSpCas9	negative selection	5304036
119206552	119206574	11	-	27760321	MOLM13	viability	GTCCACCGTCCCCGGCGGGTGG	CBL	ENSG00000110395	-0.8404375072519327	[880,705]	[381,134]	-5	hSpCas9	negative selection	5387495
119232493	119232515	11	-	27760321	MOLM13	viability	GCAGGTCTAAGATATAAGGTGG	CBL	ENSG00000110395	-2.7609456885088473	[100,55]	[0,10]	-8	hSpCas9	negative selection	5387496
119273878	119273900	11	+	27760321	MOLM13	viability	CCTTGGAAGAGCTTTCGACAGG	CBL	ENSG00000110395	-0.712782070943167	[458,390]	[6,263]	-4	hSpCas9	negative selection	5387497
119273954	119273976	11	-	27760321	MOLM13	viability	TTGCAGGTCAGATCAATAGTGG	CBL	ENSG00000110395	0.8709060921935547	[169,118]	[60,220]	6	hSpCas9	negative selection	5387498
119278564	119278586	11	-	27760321	MOLM13	viability	CAAACGGATCTACCACGATGGG	CBL	ENSG00000110395	-0.4785820444343961	[548,454]	[230,177]	-3	hSpCas9	negative selection	5387499
119206031	119206054	11	+	27661255	K562	viability	GGAAGACGGGCACAGAAACCTGG	CBL	ENSG00000110395	0.4861434883965657	[959,1153]	[1249,1117]	9	dCas9-KRAB	negative selection	5468326
119206564	119206587	11	+	27661255	K562	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	0.6285049430418317	[640,838]	[896,919]	9	dCas9-KRAB	negative selection	5468327
119206663	119206686	11	+	27661255	K562	viability	GCCGCGGGGAGGGGAACGAGCGG	CBL	ENSG00000110395	0.6354481729624656	[409,445]	[539,521]	9	dCas9-KRAB	negative selection	5468328
119206763	119206786	11	+	27661255	K562	viability	GGGCAGGGACGAGGCCGGGAGGG	CBL	ENSG00000110395	0.0775078311991525	[1567,1384]	[1310,1192]	2	dCas9-KRAB	negative selection	5468329
119206338	119206361	11	-	27661255	K562	viability	GGGAGAGAAGCAGGGCGTGAAGG	CBL	ENSG00000110395	0.5206465908831659	[1123,1325]	[1512,1302]	9	dCas9-KRAB	negative selection	5468330
119206107	119206130	11	+	27661255	K562	viability	GGGATCGTCGCTGCCCAGTCCGG	CBL	ENSG00000110395	0.07097906995564474	[1992,2087]	[1822,1614]	2	dCas9-KRAB	negative selection	5468614
119206113	119206136	11	+	27661255	K562	viability	GTCGCTGCCCAGTCCGGCCGCGG	CBL	ENSG00000110395	0.2562803148604058	[1573,1945]	[1810,1554]	8	dCas9-KRAB	negative selection	5468615
119206165	119206188	11	-	27661255	K562	viability	GGCGCGTCCCGGAGGCGGACCGG	CBL	ENSG00000110395	0.23703703837424941	[801,879]	[750,823]	7	dCas9-KRAB	negative selection	5468617
119274003	119274026	11	+	27260156	BXPC3	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.4241711593614653	[341]	[393,512,514,504]	8	hSpCas9	negative selection	5533553
119232469	119232492	11	-	27260156	BXPC3	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.4775012638416393	[458]	[710,557,676,731]	8	hSpCas9	negative selection	5533554
119206559	119206582	11	-	27260156	BXPC3	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.2777090047541766	[1293]	[1335,1695,1621,1964]	6	hSpCas9	negative selection	5533555
119206475	119206498	11	+	27260156	BXPC3	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.14479748860672345	[391]	[408,449,504,450]	3	hSpCas9	negative selection	5597831
119273861	119273884	11	+	27260156	BXPC3	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.005649354001298512	[197]	[182,161,219,271]	0	hSpCas9	negative selection	5597832
119232633	119232656	11	+	27260156	BXPC3	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.265876705780806	[357]	[462,362,403,586]	6	hSpCas9	negative selection	5597833
119274003	119274026	11	+	27260156	A673	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.6065258760234776	[341]	[542,623,691,630]	9	hSpCas9	negative selection	5654804
119232469	119232492	11	-	27260156	A673	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.46112304396461384	[458]	[821,696,678,849]	9	hSpCas9	negative selection	5654805
119206559	119206582	11	-	27260156	A673	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.37995926028023574	[1293]	[2305,1885,1934,1991]	8	hSpCas9	negative selection	5654806
119206475	119206498	11	+	27260156	A673	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.03979386829617271	[391]	[498,441,450,442]	-1	hSpCas9	negative selection	5719082
119273861	119273884	11	+	27260156	A673	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.04776930424765058	[197]	[246,227,211,234]	-1	hSpCas9	negative selection	5719083
119232633	119232656	11	+	27260156	A673	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.2055178334058152	[357]	[522,499,480,479]	5	hSpCas9	negative selection	5719084
119274003	119274026	11	+	27260156	A375	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.9750572286938327	[341]	[682,819,780,849]	9	hSpCas9	negative selection	5776055
119232469	119232492	11	-	27260156	A375	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.7629349338327758	[458]	[770,805,1114,925]	9	hSpCas9	negative selection	5776056
119206559	119206582	11	-	27260156	A375	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.22990729961405743	[1293]	[1922,2102,1792,1360]	3	hSpCas9	negative selection	5776057
119206475	119206498	11	+	27260156	A375	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.13204618150480218	[391]	[343,707,547,439]	2	hSpCas9	negative selection	5840333
119273861	119273884	11	+	27260156	A375	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.35515042243596606	[197]	[147,143,159,255]	-5	hSpCas9	negative selection	5840334
119232633	119232656	11	+	27260156	A375	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.06392859876394474	[357]	[295,547,472,311]	-1	hSpCas9	negative selection	5840335
119274003	119274026	11	+	27260156	COLO741	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.4114357069262851	[341]	[677,417,648]	8	hSpCas9	negative selection	5897306
119232469	119232492	11	-	27260156	COLO741	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.4327539602377606	[458]	[853,798,729]	8	hSpCas9	negative selection	5897307
119206559	119206582	11	-	27260156	COLO741	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.24076477748911995	[1293]	[1829,2197,1827]	5	hSpCas9	negative selection	5897308
119206475	119206498	11	+	27260156	COLO741	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.016504100264857408	[391]	[620,578,340]	0	hSpCas9	negative selection	5961584
119273861	119273884	11	+	27260156	COLO741	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.08515214376153768	[197]	[254,176,280]	-2	hSpCas9	negative selection	5961585
119232633	119232656	11	+	27260156	COLO741	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.10992453103278238	[357]	[416,653,408]	2	hSpCas9	negative selection	5961586
119274003	119274026	11	+	27260156	CAL120	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.23971543767525613	[341]	[407,688,397]	3	hSpCas9	negative selection	6018557
119232469	119232492	11	-	27260156	CAL120	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.7105631324198513	[458]	[870,1205,720]	9	hSpCas9	negative selection	6018558
119206559	119206582	11	-	27260156	CAL120	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.44272750505885705	[1293]	[2446,1982,2173]	6	hSpCas9	negative selection	6018559
119206475	119206498	11	+	27260156	CAL120	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.14969744351783493	[391]	[482,677,454]	2	hSpCas9	negative selection	6082835
119273861	119273884	11	+	27260156	CAL120	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.02097316137119032	[197]	[350,280,114]	0	hSpCas9	negative selection	6082836
119232633	119232656	11	+	27260156	CAL120	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.3862695562952987	[357]	[246,525,916]	6	hSpCas9	negative selection	6082837
119274003	119274026	11	+	27260156	CADOES1	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.8814472955064289	[341]	[475,669,722,470]	9	hSpCas9	negative selection	6139808
119232469	119232492	11	-	27260156	CADOES1	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.648122234090343	[458]	[572,823,599,679]	9	hSpCas9	negative selection	6139809
119206559	119206582	11	-	27260156	CADOES1	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.48525528690609354	[1293]	[1887,1421,1505,1930]	7	hSpCas9	negative selection	6139810
119206475	119206498	11	+	27260156	CADOES1	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.16974431712572216	[391]	[353,378,483,423]	3	hSpCas9	negative selection	6204086
119273861	119273884	11	+	27260156	CADOES1	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.010270985713426883	[197]	[125,285,155,162]	0	hSpCas9	negative selection	6204087
119232633	119232656	11	+	27260156	CADOES1	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.703758836125808	[357]	[499,678,642,339]	9	hSpCas9	negative selection	6204088
119274003	119274026	11	+	27260156	EWS502	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.7304221404117187	[341]	[478,556,619,774]	9	hSpCas9	negative selection	6261059
119232469	119232492	11	-	27260156	EWS502	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.6179227850078611	[458]	[664,509,805,1041]	9	hSpCas9	negative selection	6261060
119206559	119206582	11	-	27260156	EWS502	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.4214459184649524	[1293]	[1622,1799,1997,1951]	7	hSpCas9	negative selection	6261061
119206475	119206498	11	+	27260156	EWS502	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.012080472648285434	[391]	[346,452,502,344]	0	hSpCas9	negative selection	6325337
119273861	119273884	11	+	27260156	EWS502	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.13682743615943815	[197]	[190,226,121,221]	-2	hSpCas9	negative selection	6325338
119232633	119232656	11	+	27260156	EWS502	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.22034291959575525	[357]	[409,454,315,596]	4	hSpCas9	negative selection	6325339
119274003	119274026	11	+	27260156	EW8	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.7992820764853863	[341]	[659,566,275,479]	9	hSpCas9	negative selection	6382310
119232469	119232492	11	-	27260156	EW8	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.5177405898520332	[458]	[607,489,579,450]	8	hSpCas9	negative selection	6382311
119206559	119206582	11	-	27260156	EW8	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.38441734771022373	[1293]	[1946,1143,1122,1361]	7	hSpCas9	negative selection	6382312
119206475	119206498	11	+	27260156	EW8	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.11212142409626852	[391]	[508,297,185,423]	2	hSpCas9	negative selection	6446588
119273861	119273884	11	+	27260156	EW8	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.049510533526797795	[197]	[110,226,162,112]	-1	hSpCas9	negative selection	6446589
119232633	119232656	11	+	27260156	EW8	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.07578276760217162	[357]	[251,421,335,201]	1	hSpCas9	negative selection	6446590
119274003	119274026	11	+	27260156	CORL105	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.5879831204846928	[341]	[628,493,746,562]	9	hSpCas9	negative selection	6503561
119232469	119232492	11	-	27260156	CORL105	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.4478082139526831	[458]	[761,790,753,627]	7	hSpCas9	negative selection	6503562
119206559	119206582	11	-	27260156	CORL105	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.2596686655526619	[1293]	[1714,1997,2037,1531]	5	hSpCas9	negative selection	6503563
119206475	119206498	11	+	27260156	CORL105	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.0083276201685768	[391]	[659,438,324,387]	0	hSpCas9	negative selection	6567839
119273861	119273884	11	+	27260156	CORL105	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.6138801460596441	[197]	[100,258,93,138]	-8	hSpCas9	negative selection	6567840
119232633	119232656	11	+	27260156	CORL105	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.1521082649053152	[357]	[438,472,499,454]	3	hSpCas9	negative selection	6567841
119274003	119274026	11	+	27260156	HS294T	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.6052812496433685	[341]	[193,253,217,123]	7	hSpCas9	negative selection	6624812
119232469	119232492	11	-	27260156	HS294T	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.7348024864661826	[458]	[381,223,249,322]	8	hSpCas9	negative selection	6624813
119206559	119206582	11	-	27260156	HS294T	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	-0.03321973322935401	[1293]	[475,436,455,607]	0	hSpCas9	negative selection	6624814
119206475	119206498	11	+	27260156	HS294T	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.7015615321334394	[391]	[308,152,109,442]	8	hSpCas9	negative selection	6689090
119273861	119273884	11	+	27260156	HS294T	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.14189627544480587	[197]	[93,59,42,79]	-2	hSpCas9	negative selection	6689091
119232633	119232656	11	+	27260156	HS294T	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.4368697560946444	[357]	[89,292,242,116]	6	hSpCas9	negative selection	6689092
119274003	119274026	11	+	27260156	HCC44	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.40757627976015476	[341]	[642,431,570,437]	6	hSpCas9	negative selection	6746063
119232469	119232492	11	-	27260156	HCC44	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.3591452520021608	[458]	[639,598,815,636]	6	hSpCas9	negative selection	6746064
119206559	119206582	11	-	27260156	HCC44	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.3609715418532202	[1293]	[1625,1715,2416,1837]	6	hSpCas9	negative selection	6746065
119206475	119206498	11	+	27260156	HCC44	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.26791594529294593	[391]	[529,384,722,545]	4	hSpCas9	negative selection	6810341
119273861	119273884	11	+	27260156	HCC44	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.22851648203090313	[197]	[271,148,189,165]	-4	hSpCas9	negative selection	6810342
119232633	119232656	11	+	27260156	HCC44	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.09721975305315689	[357]	[709,382,348,308]	1	hSpCas9	negative selection	6810343
119274003	119274026	11	+	27260156	G402	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	1.5507391312442214	[341]	[571,932,737,2469]	9	hSpCas9	negative selection	6867314
119232469	119232492	11	-	27260156	G402	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	1.6472331129771107	[458]	[2385,2283,1608,895]	9	hSpCas9	negative selection	6867315
119206559	119206582	11	-	27260156	G402	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	1.2427300943575237	[1293]	[3895,3416,4989,2684]	9	hSpCas9	negative selection	6867316
119206475	119206498	11	+	27260156	G402	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.7694969982954585	[391]	[418,842,961,970]	8	hSpCas9	negative selection	6931592
119273861	119273884	11	+	27260156	G402	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.6289010466215794	[197]	[283,403,487,308]	7	hSpCas9	negative selection	6931593
119232633	119232656	11	+	27260156	G402	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	1.5213047487568854	[357]	[1073,1206,1719,993]	9	hSpCas9	negative selection	6931594
119274003	119274026	11	+	27260156	L33	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.22558450964529533	[341]	[388,192,169,467]	5	hSpCas9	negative selection	6988565
119232469	119232492	11	-	27260156	L33	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.19888972137633779	[458]	[530,220,343,489]	4	hSpCas9	negative selection	6988566
119206559	119206582	11	-	27260156	L33	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.12410579640305586	[1293]	[1295,554,934,1504]	2	hSpCas9	negative selection	6988567
119206475	119206498	11	+	27260156	L33	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.03132949546984487	[391]	[378,127,245,450]	0	hSpCas9	negative selection	7052843
119273861	119273884	11	+	27260156	L33	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.4493335865952435	[197]	[158,53,99,129]	-8	hSpCas9	negative selection	7052844
119232633	119232656	11	+	27260156	L33	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.019898229926432864	[357]	[463,145,215,285]	0	hSpCas9	negative selection	7052845
119274003	119274026	11	+	27260156	K562	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.4772602243683318	[341]	[418,650,311,328]	6	hSpCas9	negative selection	7109816
119232469	119232492	11	-	27260156	K562	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.5431216883572678	[458]	[541,811,630,414]	7	hSpCas9	negative selection	7109817
119206559	119206582	11	-	27260156	K562	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.5791286609509598	[1293]	[1941,1827,1541,1582]	7	hSpCas9	negative selection	7109818
119206475	119206498	11	+	27260156	K562	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.2782255209112729	[391]	[365,518,669,161]	3	hSpCas9	negative selection	7174094
119273861	119273884	11	+	27260156	K562	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.206212823505032	[197]	[201,117,139,150]	-3	hSpCas9	negative selection	7174095
119232633	119232656	11	+	27260156	K562	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.6819374263397278	[357]	[623,644,443,357]	8	hSpCas9	negative selection	7174096
119274003	119274026	11	+	27260156	HT29	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.6905000474117626	[341]	[796,502,719,655]	9	hSpCas9	negative selection	7231067
119232469	119232492	11	-	27260156	HT29	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.34314652550827623	[458]	[1054,854,522,462]	6	hSpCas9	negative selection	7231068
119206559	119206582	11	-	27260156	HT29	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.22804280116374764	[1293]	[1752,2216,1682,1740]	4	hSpCas9	negative selection	7231069
119206475	119206498	11	+	27260156	HT29	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.19675782659579155	[391]	[499,435,412,329]	-4	hSpCas9	negative selection	7295345
119273861	119273884	11	+	27260156	HT29	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.2804906709815935	[197]	[329,209,347,276]	5	hSpCas9	negative selection	7295346
119232633	119232656	11	+	27260156	HT29	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.3459442748200402	[357]	[533,535,568,564]	6	hSpCas9	negative selection	7295347
119274003	119274026	11	+	27260156	MHHES1	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.89154179101752	[341]	[817,819,528,699]	9	hSpCas9	negative selection	7352318
119232469	119232492	11	-	27260156	MHHES1	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.6622603729130453	[458]	[628,1136,986,569]	9	hSpCas9	negative selection	7352319
119206559	119206582	11	-	27260156	MHHES1	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.43383854997028926	[1293]	[1933,2214,1983,1764]	7	hSpCas9	negative selection	7352320
119206475	119206498	11	+	27260156	MHHES1	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.043003957097979384	[391]	[419,387,481,412]	-1	hSpCas9	negative selection	7416596
119273861	119273884	11	+	27260156	MHHES1	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.22602459815912535	[197]	[212,456,319,99]	4	hSpCas9	negative selection	7416597
119232633	119232656	11	+	27260156	MHHES1	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.09889203968342714	[357]	[578,351,356,258]	-2	hSpCas9	negative selection	7416598
119274003	119274026	11	+	27260156	MEWO	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.4289434364938767	[341]	[540,534,236]	8	hSpCas9	negative selection	7473569
119232469	119232492	11	-	27260156	MEWO	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.4820637653192876	[458]	[803,559,474]	8	hSpCas9	negative selection	7473570
119206559	119206582	11	-	27260156	MEWO	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.2699780353741781	[1293]	[1603,1432,1369]	6	hSpCas9	negative selection	7473571
119206475	119206498	11	+	27260156	MEWO	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.19569502170379888	[391]	[400,271,583]	4	hSpCas9	negative selection	7537847
119273861	119273884	11	+	27260156	MEWO	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.13033365295086963	[197]	[148,162,285]	3	hSpCas9	negative selection	7537848
119232633	119232656	11	+	27260156	MEWO	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.025724137707498984	[357]	[370,348,274]	0	hSpCas9	negative selection	7537849
119274003	119274026	11	+	27260156	LNCAPCLONEFGC	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.8543106665651696	[341]	[554,534,635,526]	9	hSpCas9	negative selection	7594820
119232469	119232492	11	-	27260156	LNCAPCLONEFGC	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.38294462026933973	[458]	[511,451,636,587]	6	hSpCas9	negative selection	7594821
119206559	119206582	11	-	27260156	LNCAPCLONEFGC	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.3548005426131915	[1293]	[1315,1513,1562,1613]	5	hSpCas9	negative selection	7594822
119206475	119206498	11	+	27260156	LNCAPCLONEFGC	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.20774291326525948	[391]	[492,451,310,364]	3	hSpCas9	negative selection	7659098
119273861	119273884	11	+	27260156	LNCAPCLONEFGC	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.4947931147196185	[197]	[56,139,210,113]	-6	hSpCas9	negative selection	7659099
119232633	119232656	11	+	27260156	LNCAPCLONEFGC	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.0991553270451287	[357]	[323,323,520,247]	1	hSpCas9	negative selection	7659100
119274003	119274026	11	+	27260156	PANC0327	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.5537930367613848	[341]	[392,408,410,570]	7	hSpCas9	negative selection	7716071
119232469	119232492	11	-	27260156	PANC0327	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.5431460041605256	[458]	[796,577,526,492]	7	hSpCas9	negative selection	7716072
119206559	119206582	11	-	27260156	PANC0327	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.10435448458161645	[1293]	[1329,1433,917,1241]	1	hSpCas9	negative selection	7716073
119206475	119206498	11	+	27260156	PANC0327	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.14519279724060213	[391]	[367,560,284,301]	2	hSpCas9	negative selection	7780349
119273861	119273884	11	+	27260156	PANC0327	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.4970018156371021	[197]	[203,123,76,99]	-6	hSpCas9	negative selection	7780350
119232633	119232656	11	+	27260156	PANC0327	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.14730121213640124	[357]	[371,320,211,508]	2	hSpCas9	negative selection	7780351
119274003	119274026	11	+	27260156	NCIH2009	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.7117896680242999	[341]	[862,802,695]	8	hSpCas9	negative selection	7837322
119232469	119232492	11	-	27260156	NCIH2009	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.7421894978012198	[458]	[889,971,1319]	8	hSpCas9	negative selection	7837323
119206559	119206582	11	-	27260156	NCIH2009	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.5507593217413336	[1293]	[3031,2833,2146]	7	hSpCas9	negative selection	7837324
119206475	119206498	11	+	27260156	NCIH2009	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.04164201083799979	[391]	[584,641,465]	0	hSpCas9	negative selection	7901600
119273861	119273884	11	+	27260156	NCIH2009	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.20257886153076843	[197]	[250,437,249]	2	hSpCas9	negative selection	7901601
119232633	119232656	11	+	27260156	NCIH2009	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.4076258912124169	[357]	[774,684,550]	5	hSpCas9	negative selection	7901602
119274003	119274026	11	+	27260156	NCIH1373	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	1.329264600503397	[341]	[585,1280,1022,224]	9	hSpCas9	negative selection	7958573
119232469	119232492	11	-	27260156	NCIH1373	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	1.1779198765586234	[458]	[1392,904,1196,320]	9	hSpCas9	negative selection	7958574
119206559	119206582	11	-	27260156	NCIH1373	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.8157107040755014	[1293]	[4327,2177,1727,599]	7	hSpCas9	negative selection	7958575
119206475	119206498	11	+	27260156	NCIH1373	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.756152483562524	[391]	[656,313,856,313]	7	hSpCas9	negative selection	8022851
119273861	119273884	11	+	27260156	NCIH1373	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.17376318514825262	[197]	[240,421,100,56]	1	hSpCas9	negative selection	8022852
119232633	119232656	11	+	27260156	NCIH1373	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.2891568984148837	[357]	[571,385,630,100]	3	hSpCas9	negative selection	8022853
119274003	119274026	11	+	27260156	PATU8902	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	1.2667192019901363	[341]	[1065,1090,1020,1468]	9	hSpCas9	negative selection	8079824
119232469	119232492	11	-	27260156	PATU8902	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.7924330479435449	[458]	[1159,788,1233,1214]	8	hSpCas9	negative selection	8079825
119206559	119206582	11	-	27260156	PATU8902	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.33449974208022226	[1293]	[1905,2138,2308,2771]	3	hSpCas9	negative selection	8079826
119206475	119206498	11	+	27260156	PATU8902	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.5460160444876838	[391]	[512,1522,557,636]	6	hSpCas9	negative selection	8144102
119273861	119273884	11	+	27260156	PATU8902	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.4718990440772832	[197]	[117,160,102,469]	-4	hSpCas9	negative selection	8144103
119232633	119232656	11	+	27260156	PATU8902	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.647051319392453	[357]	[535,1151,698,751]	6	hSpCas9	negative selection	8144104
119274003	119274026	11	+	27260156	PANC1	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.7557206755542366	[341]	[666,550,384,395]	9	hSpCas9	negative selection	8201075
119232469	119232492	11	-	27260156	PANC1	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.7362856431099744	[458]	[529,684,942,495]	9	hSpCas9	negative selection	8201076
119206559	119206582	11	-	27260156	PANC1	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.4406096756851343	[1293]	[1465,2354,1293,1129]	7	hSpCas9	negative selection	8201077
119206475	119206498	11	+	27260156	PANC1	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.021544202710381155	[391]	[261,505,343,292]	0	hSpCas9	negative selection	8265353
119273861	119273884	11	+	27260156	PANC1	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.4548509851471071	[197]	[207,155,396,164]	7	hSpCas9	negative selection	8265354
119232633	119232656	11	+	27260156	PANC1	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.6422485448414352	[357]	[397,566,338,604]	9	hSpCas9	negative selection	8265355
119274003	119274026	11	+	27260156	PANC0813	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.6198584717972724	[341]	[645,527,793,509]	8	hSpCas9	negative selection	8322326
119232469	119232492	11	-	27260156	PANC0813	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.39982397742036274	[458]	[591,517,1000,722]	6	hSpCas9	negative selection	8322327
119206559	119206582	11	-	27260156	PANC0813	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.43617406343636334	[1293]	[2461,2260,1728,1819]	7	hSpCas9	negative selection	8322328
119206475	119206498	11	+	27260156	PANC0813	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.04350900908723382	[391]	[567,465,402,364]	0	hSpCas9	negative selection	8386604
119273861	119273884	11	+	27260156	PANC0813	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.33874623922211256	[197]	[363,367,227,225]	5	hSpCas9	negative selection	8386605
119232633	119232656	11	+	27260156	PANC0813	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.36385238627245	[357]	[517,473,696,476]	6	hSpCas9	negative selection	8386606
119274003	119274026	11	+	27260156	RDES	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.767525080282981	[341]	[575,667,685,761]	9	hSpCas9	negative selection	8443577
119232469	119232492	11	-	27260156	RDES	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.5752527983747413	[458]	[478,933,961,811]	8	hSpCas9	negative selection	8443578
119206559	119206582	11	-	27260156	RDES	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.3083116084301538	[1293]	[1400,1794,2116,2162]	5	hSpCas9	negative selection	8443579
119206475	119206498	11	+	27260156	RDES	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.009323909141040476	[391]	[436,442,483,438]	0	hSpCas9	negative selection	8507855
119273861	119273884	11	+	27260156	RDES	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.159886522052189	[197]	[156,168,240,266]	-3	hSpCas9	negative selection	8507856
119232633	119232656	11	+	27260156	RDES	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.11610016418198926	[357]	[248,549,454,570]	2	hSpCas9	negative selection	8507857
119274003	119274026	11	+	27260156	PC3	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.4924331054117709	[341]	[270,576,814,425]	8	hSpCas9	negative selection	8564828
119232469	119232492	11	-	27260156	PC3	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.5525624172635389	[458]	[445,640,1237,608]	9	hSpCas9	negative selection	8564829
119206559	119206582	11	-	27260156	PC3	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.24014654846654082	[1293]	[1006,1155,3033,1582]	5	hSpCas9	negative selection	8564830
119206475	119206498	11	+	27260156	PC3	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.14507229997111565	[391]	[189,391,530,410]	-3	hSpCas9	negative selection	8629106
119273861	119273884	11	+	27260156	PC3	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.10690226192092367	[197]	[86,140,409,215]	-2	hSpCas9	negative selection	8629107
119232633	119232656	11	+	27260156	PC3	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.21345882537149677	[357]	[240,363,961,339]	5	hSpCas9	negative selection	8629108
119274003	119274026	11	+	27260156	PATU8988T	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.8370472338977557	[341]	[669,450,622,604]	9	hSpCas9	negative selection	8686079
119232469	119232492	11	-	27260156	PATU8988T	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.4355926755516904	[458]	[560,714,417,728]	7	hSpCas9	negative selection	8686080
119206559	119206582	11	-	27260156	PATU8988T	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.42251254125813964	[1293]	[1490,1830,1298,2138]	7	hSpCas9	negative selection	8686081
119206475	119206498	11	+	27260156	PATU8988T	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.01263164496302921	[391]	[384,426,265,434]	0	hSpCas9	negative selection	8750357
119273861	119273884	11	+	27260156	PATU8988T	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.16814387597760327	[197]	[91,179,287,115]	-3	hSpCas9	negative selection	8750358
119232633	119232656	11	+	27260156	PATU8988T	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	-0.5181613765604227	[357]	[262,247,303,142]	-7	hSpCas9	negative selection	8750359
119274003	119274026	11	+	27260156	T47D	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.654954939111529	[341]	[636,581,717,572]	9	hSpCas9	negative selection	8807330
119232469	119232492	11	-	27260156	T47D	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.3790525073030452	[458]	[764,624,594,807]	7	hSpCas9	negative selection	8807331
119206559	119206582	11	-	27260156	T47D	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.2905296216657651	[1293]	[2013,1613,1679,2097]	6	hSpCas9	negative selection	8807332
119206475	119206498	11	+	27260156	T47D	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.01663371336454894	[391]	[514,408,491,390]	0	hSpCas9	negative selection	8871608
119273861	119273884	11	+	27260156	T47D	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.2080653459638131	[197]	[257,182,200,156]	-4	hSpCas9	negative selection	8871609
119232633	119232656	11	+	27260156	T47D	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.1891348119038565	[357]	[520,441,446,495]	4	hSpCas9	negative selection	8871610
119274003	119274026	11	+	27260156	SU8686	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.42263767718854384	[341]	[369,361,554,570]	7	hSpCas9	negative selection	8928581
119232469	119232492	11	-	27260156	SU8686	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.6435565134156953	[458]	[688,574,685,945]	9	hSpCas9	negative selection	8928582
119206559	119206582	11	-	27260156	SU8686	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.47745680110350386	[1293]	[1762,1422,1844,2222]	7	hSpCas9	negative selection	8928583
119206475	119206498	11	+	27260156	SU8686	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.07941001700347916	[391]	[411,468,316,434]	1	hSpCas9	negative selection	8992859
119273861	119273884	11	+	27260156	SU8686	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.10320426121550375	[197]	[194,209,198,244]	1	hSpCas9	negative selection	8992860
119232633	119232656	11	+	27260156	SU8686	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.10163097819366324	[357]	[241,428,355,525]	1	hSpCas9	negative selection	8992861
119274003	119274026	11	+	27260156	SKES1	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.47444040087722805	[341]	[572,502,310,517]	8	hSpCas9	negative selection	9049832
119232469	119232492	11	-	27260156	SKES1	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.5582437484418523	[458]	[658,750,773,528]	9	hSpCas9	negative selection	9049833
119206559	119206582	11	-	27260156	SKES1	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.48375922384782855	[1293]	[1968,2199,1626,1512]	8	hSpCas9	negative selection	9049834
119206475	119206498	11	+	27260156	SKES1	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.08651484082827687	[391]	[378,354,573,180]	-2	hSpCas9	negative selection	9114110
119273861	119273884	11	+	27260156	SKES1	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.4922680749851166	[197]	[395,316,209,214]	8	hSpCas9	negative selection	9114111
119232633	119232656	11	+	27260156	SKES1	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.7212058764687866	[357]	[729,652,443,554]	9	hSpCas9	negative selection	9114112
119274003	119274026	11	+	27260156	TOV112D	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.4435982509452841	[341]	[711,637,193,383]	7	hSpCas9	negative selection	9171083
119232469	119232492	11	-	27260156	TOV112D	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.5010516874566086	[458]	[526,747,547,787]	8	hSpCas9	negative selection	9171084
119206559	119206582	11	-	27260156	TOV112D	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.35551977708452154	[1293]	[2093,1522,1489,1529]	6	hSpCas9	negative selection	9171085
119206475	119206498	11	+	27260156	TOV112D	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	-0.1275168318577436	[391]	[429,238,373,369]	-2	hSpCas9	negative selection	9235361
119273861	119273884	11	+	27260156	TOV112D	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	-0.08808308802901976	[197]	[214,200,225,111]	-2	hSpCas9	negative selection	9235362
119232633	119232656	11	+	27260156	TOV112D	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.4569626049884735	[357]	[611,452,435,467]	8	hSpCas9	negative selection	9235363
119274003	119274026	11	+	27260156	TC71	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.35061208176883385	[341]	[505,446,503,406]	8	hSpCas9	negative selection	9292334
119232469	119232492	11	-	27260156	TC71	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.6164330607901807	[458]	[724,641,874,772]	9	hSpCas9	negative selection	9292335
119206559	119206582	11	-	27260156	TC71	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.4662471952981495	[1293]	[1712,1983,1922,2057]	9	hSpCas9	negative selection	9292336
119206475	119206498	11	+	27260156	TC71	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.05116935895636876	[391]	[287,555,511,382]	1	hSpCas9	negative selection	9356612
119273861	119273884	11	+	27260156	TC71	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.08055520899532209	[197]	[143,273,210,273]	2	hSpCas9	negative selection	9356613
119232633	119232656	11	+	27260156	TC71	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.4678820107018828	[357]	[351,582,585,608]	9	hSpCas9	negative selection	9356614
119274003	119274026	11	+	27260156	TC32	viability	CATCTTTACCCGACTCTTTCAGG	CBL	ENSG00000110395	0.7193118696754992	[341]	[491,347,800,567]	9	hSpCas9	negative selection	9413585
119232469	119232492	11	-	27260156	TC32	viability	CTATTCTTTAGCGCCAGCTTTGG	CBL	ENSG00000110395	0.7337991839291398	[458]	[736,460,1075,709]	9	hSpCas9	negative selection	9413586
119206559	119206582	11	-	27260156	TC32	viability	ATCTTCTTGTCCACCGTCCCCGG	CBL	ENSG00000110395	0.8091539353928383	[1293]	[2112,1561,2792,2266]	9	hSpCas9	negative selection	9413587
119206475	119206498	11	+	27260156	TC32	viability	TCGGGTTCGGGTGGCCTGATTGG	CBL	ENSG00000110395	0.39831996501994404	[391]	[378,490,604,466]	7	hSpCas9	negative selection	9477863
119273861	119273884	11	+	27260156	TC32	viability	TCCCCAGGACAATAGTCCCTTGG	CBL	ENSG00000110395	0.5018917264588011	[197]	[348,172,243,292]	8	hSpCas9	negative selection	9477864
119232633	119232656	11	+	27260156	TC32	viability	GCAAACCATAAGCCTCTTCAAGG	CBL	ENSG00000110395	0.7239012538832844	[357]	[565,336,766,643]	9	hSpCas9	negative selection	9477865
119206416	119206439	11	-	27869803	HPAFII	viability after 27 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	-0.14344879148621673	[245]	[109,122,NaN]	-1	hSpCas9	negative selection	9540127
119232636	119232659	11	+	27869803	HPAFII	viability after 27 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.01758490283042119	[184]	[68,122,NaN]	0	hSpCas9	negative selection	9540128
119273877	119273900	11	-	27869803	HPAFII	viability after 27 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.2338461484479285	[260]	[138,179,NaN]	1	hSpCas9	negative selection	9540130
119276006	119276029	11	-	27869803	HPAFII	viability after 27 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	1.4442408670008615	[269]	[544,253,NaN]	9	hSpCas9	negative selection	9540131
119277823	119277846	11	+	27869803	HPAFII	viability after 27 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.11376794190360782	[228]	[102,152,NaN]	0	hSpCas9	negative selection	9540132
119278254	119278277	11	-	27869803	HPAFII	viability after 27 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.6049830507122962	[48]	[0,70,NaN]	5	hSpCas9	negative selection	9540133
119206416	119206439	11	-	27869803	HPAFII	viability after 15 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.41057298507100576	[245]	[409,314,NaN]	5	hSpCas9	negative selection	9622576
119232636	119232659	11	+	27869803	HPAFII	viability after 15 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.574846605997858	[184]	[334,271,NaN]	6	hSpCas9	negative selection	9622577
119273877	119273900	11	-	27869803	HPAFII	viability after 15 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.020467275973281532	[260]	[413,203,NaN]	0	hSpCas9	negative selection	9622579
119276006	119276029	11	-	27869803	HPAFII	viability after 15 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.793482813210187	[269]	[682,390,NaN]	8	hSpCas9	negative selection	9622580
119277823	119277846	11	+	27869803	HPAFII	viability after 15 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	-0.036765480015553104	[228]	[279,214,NaN]	0	hSpCas9	negative selection	9622581
119278254	119278277	11	-	27869803	HPAFII	viability after 15 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.2369914484252824	[48]	[29,81,NaN]	2	hSpCas9	negative selection	9622582
119206416	119206439	11	-	27869803	ASPC1	viability after 36 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.5449683468356322	[591]	[212,655,78]	5	hSpCas9	negative selection	9705025
119232636	119232659	11	+	27869803	ASPC1	viability after 36 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	1.1096675489361358	[606]	[490,301,551]	9	hSpCas9	negative selection	9705026
119273877	119273900	11	-	27869803	ASPC1	viability after 36 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.6728864618523717	[601]	[309,290,383]	6	hSpCas9	negative selection	9705028
119276006	119276029	11	-	27869803	ASPC1	viability after 36 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	1.2680514627845747	[585]	[1168,314,153]	9	hSpCas9	negative selection	9705029
119277823	119277846	11	+	27869803	ASPC1	viability after 36 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	-0.4063250175546445	[491]	[189,175,48]	-4	hSpCas9	negative selection	9705030
119278254	119278277	11	-	27869803	ASPC1	viability after 36 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.22008127311633574	[170]	[0,183,25]	2	hSpCas9	negative selection	9705031
119206416	119206439	11	-	27869803	PATU8988S	viability after 35 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.15989900445865432	[487]	[253,184,NaN]	1	hSpCas9	negative selection	9787474
119232636	119232659	11	+	27869803	PATU8988S	viability after 35 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.1167736776051937	[564]	[148,270,NaN]	-1	hSpCas9	negative selection	9787475
119273877	119273900	11	-	27869803	PATU8988S	viability after 35 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.1281831141302474	[661]	[244,337,NaN]	1	hSpCas9	negative selection	9787477
119276006	119276029	11	-	27869803	PATU8988S	viability after 35 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.8633225901518654	[568]	[373,459,NaN]	8	hSpCas9	negative selection	9787478
119277823	119277846	11	+	27869803	PATU8988S	viability after 35 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.2182199712223723	[414]	[165,222,NaN]	2	hSpCas9	negative selection	9787479
119278254	119278277	11	-	27869803	PATU8988S	viability after 35 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	0.2618421961414148	[154]	[8,140,NaN]	3	hSpCas9	negative selection	9787480
119206416	119206439	11	-	27869803	PATU8988S	viability after 31 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.24372108088691885	[487]	[225,235,NaN]	3	hSpCas9	negative selection	9869923
119232636	119232659	11	+	27869803	PATU8988S	viability after 31 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.08895443686739171	[564]	[107,343,NaN]	-1	hSpCas9	negative selection	9869924
119273877	119273900	11	-	27869803	PATU8988S	viability after 31 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.15856440560985813	[661]	[269,325,NaN]	2	hSpCas9	negative selection	9869926
119276006	119276029	11	-	27869803	PATU8988S	viability after 31 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.44482993908709106	[568]	[237,398,NaN]	5	hSpCas9	negative selection	9869927
119277823	119277846	11	+	27869803	PATU8988S	viability after 31 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	-0.6613109965021957	[414]	[68,149,NaN]	-6	hSpCas9	negative selection	9869928
119278254	119278277	11	-	27869803	PATU8988S	viability after 31 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-0.4163848759464659	[154]	[0,103,NaN]	-5	hSpCas9	negative selection	9869929
119206416	119206439	11	-	27869803	HPAFII	viability after 35 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.009958490883253932	[245]	[99,153,NaN]	0	hSpCas9	negative selection	9952372
119232636	119232659	11	+	27869803	HPAFII	viability after 35 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	-0.2476792362183904	[184]	[76,80,NaN]	-1	hSpCas9	negative selection	9952373
119273877	119273900	11	-	27869803	HPAFII	viability after 35 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	0.15776753336552757	[260]	[121,175,NaN]	1	hSpCas9	negative selection	9952375
119276006	119276029	11	-	27869803	HPAFII	viability after 35 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	1.308428162936726	[269]	[465,194,NaN]	8	hSpCas9	negative selection	9952376
119277823	119277846	11	+	27869803	HPAFII	viability after 35 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	1.001873151460373	[228]	[202,264,NaN]	6	hSpCas9	negative selection	9952377
119278254	119278277	11	-	27869803	HPAFII	viability after 35 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-1.0198911717112162	[48]	[7,16,NaN]	-5	hSpCas9	negative selection	9952378
119206416	119206439	11	-	27869803	HPAFII	viability after 31 days	CTTCTTCACGTTGCCGGCCATGG	CBL	ENSG00000110395	0.4188362940405454	[245]	[118,255,NaN]	3	hSpCas9	negative selection	10034821
119232636	119232659	11	+	27869803	HPAFII	viability after 31 days	AACCATAAGCCTCTTCAAGGAGG	CBL	ENSG00000110395	0.21991585717948658	[184]	[40,207,NaN]	1	hSpCas9	negative selection	10034822
119273877	119273900	11	-	27869803	HPAFII	viability after 31 days	CCTGTCGAAAGCTCTTCCAAGGG	CBL	ENSG00000110395	-0.10692042000622046	[260]	[113,159,NaN]	0	hSpCas9	negative selection	10034824
119276006	119276029	11	-	27869803	HPAFII	viability after 31 days	CCAGACGAGTACAGCTCAGCCGG	CBL	ENSG00000110395	0.9019055323638393	[269]	[408,145,NaN]	6	hSpCas9	negative selection	10034825
119277823	119277846	11	+	27869803	HPAFII	viability after 31 days	AGACCATATCAAAGTGACCCAGG	CBL	ENSG00000110395	0.6972305273224226	[228]	[227,186,NaN]	5	hSpCas9	negative selection	10034826
119278254	119278277	11	-	27869803	HPAFII	viability after 31 days	TGTGCACATGAGGTGTCCACAGG	CBL	ENSG00000110395	-0.060825639139308496	[48]	[0,53,NaN]	0	hSpCas9	negative selection	10034827
119206564	119206587	11	+	28162770	P31FUJ	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-1.858987367862048	[70]	[22]	-8	hSpCas9	negative selection	10126465
119285258	119285281	11	-	28162770	P31FUJ	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.7061597826587516	[518]	[994]	7	hSpCas9	negative selection	10126466
119271831	119271854	11	+	28162770	P31FUJ	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.47716028784522013	[150]	[246]	5	hSpCas9	negative selection	10126467
119285047	119285070	11	-	28162770	P31FUJ	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.48914195767416413	[128]	[107]	-4	hSpCas9	negative selection	10126468
119285361	119285384	11	-	28162770	P31FUJ	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	0.45907550022328936	[38]	[62]	5	hSpCas9	negative selection	10126469
119285377	119285400	11	-	28162770	P31FUJ	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.16284630975627457	[411]	[541]	1	hSpCas9	negative selection	10126470
119232456	119232479	11	+	28162770	P31FUJ	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.056320134883764084	[560]	[633]	0	hSpCas9	negative selection	10126471
119273918	119273941	11	-	28162770	P31FUJ	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	-0.1370432216089476	[305]	[326]	-1	hSpCas9	negative selection	10126472
119278238	119278261	11	+	28162770	P31FUJ	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.6460453540123368	[657]	[1209]	7	hSpCas9	negative selection	10126473
119284981	119285004	11	-	28162770	P31FUJ	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-0.4958366102481725	[185]	[154]	-4	hSpCas9	negative selection	10126474
119206564	119206587	11	+	28162770	TF1	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10295831
119285258	119285281	11	-	28162770	TF1	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	NaN	[NaN]	[869]	1	hSpCas9	negative selection	10295832
119271831	119271854	11	+	28162770	TF1	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10295833
119285047	119285070	11	-	28162770	TF1	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	NaN	[NaN]	[142]	1	hSpCas9	negative selection	10295834
119285361	119285384	11	-	28162770	TF1	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10295835
119285377	119285400	11	-	28162770	TF1	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	NaN	[NaN]	[494]	1	hSpCas9	negative selection	10295836
119232456	119232479	11	+	28162770	TF1	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	NaN	[NaN]	[596]	1	hSpCas9	negative selection	10295837
119273918	119273941	11	-	28162770	TF1	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	NaN	[NaN]	[510]	1	hSpCas9	negative selection	10295838
119278238	119278261	11	+	28162770	TF1	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	NaN	[NaN]	[744]	1	hSpCas9	negative selection	10295839
119284981	119285004	11	-	28162770	TF1	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10295840
119206564	119206587	11	+	28162770	SKM1	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-2.6964708159381465	[21]	[5]	-9	hSpCas9	negative selection	10465197
119285258	119285281	11	-	28162770	SKM1	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.5591923462850441	[123]	[322]	5	hSpCas9	negative selection	10465198
119271831	119271854	11	+	28162770	SKM1	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	1.049841950487312	[49]	[182]	8	hSpCas9	negative selection	10465199
119285047	119285070	11	-	28162770	SKM1	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.29691065327824795	[40]	[58]	-3	hSpCas9	negative selection	10465200
119285361	119285384	11	-	28162770	SKM1	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	1.5405683813627027	[6]	[35]	9	hSpCas9	negative selection	10465201
119285377	119285400	11	-	28162770	SKM1	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.183898903417679	[121]	[244]	1	hSpCas9	negative selection	10465202
119232456	119232479	11	+	28162770	SKM1	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.26610166290331216	[116]	[171]	-2	hSpCas9	negative selection	10465203
119273918	119273941	11	-	28162770	SKM1	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.07264530183176587	[70]	[131]	0	hSpCas9	negative selection	10465204
119278238	119278261	11	+	28162770	SKM1	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.5290727425248734	[146]	[374]	5	hSpCas9	negative selection	10465205
119284981	119285004	11	-	28162770	SKM1	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-0.21319245534648174	[39]	[60]	-2	hSpCas9	negative selection	10465206
119206564	119206587	11	+	28162770	SKM1	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-2.6964708159381465	[21]	[5]	-9	hSpCas9	negative selection	10634563
119285258	119285281	11	-	28162770	SKM1	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.5591923462850441	[123]	[322]	5	hSpCas9	negative selection	10634564
119271831	119271854	11	+	28162770	SKM1	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	1.049841950487312	[49]	[182]	8	hSpCas9	negative selection	10634565
119285047	119285070	11	-	28162770	SKM1	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.29691065327824795	[40]	[58]	-3	hSpCas9	negative selection	10634566
119285361	119285384	11	-	28162770	SKM1	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	1.5405683813627027	[6]	[35]	9	hSpCas9	negative selection	10634567
119285377	119285400	11	-	28162770	SKM1	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.183898903417679	[121]	[244]	1	hSpCas9	negative selection	10634568
119232456	119232479	11	+	28162770	SKM1	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.26610166290331216	[116]	[171]	-2	hSpCas9	negative selection	10634569
119273918	119273941	11	-	28162770	SKM1	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.07264530183176587	[70]	[131]	0	hSpCas9	negative selection	10634570
119278238	119278261	11	+	28162770	SKM1	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.5290727425248734	[146]	[374]	5	hSpCas9	negative selection	10634571
119284981	119285004	11	-	28162770	SKM1	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-0.21319245534648174	[39]	[60]	-2	hSpCas9	negative selection	10634572
119206564	119206587	11	+	28162770	PL21	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	0.28030996317330326	[69]	[36]	2	hSpCas9	negative selection	10803929
119285258	119285281	11	-	28162770	PL21	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.2388431438198041	[330]	[169]	2	hSpCas9	negative selection	10803930
119271831	119271854	11	+	28162770	PL21	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.26467986668403054	[152]	[79]	2	hSpCas9	negative selection	10803931
119285047	119285070	11	-	28162770	PL21	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	0.2138145513863965	[104]	[52]	2	hSpCas9	negative selection	10803932
119285361	119285384	11	-	28162770	PL21	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	-0.6743295034268213	[10]	[2]	-5	hSpCas9	negative selection	10803933
119285377	119285400	11	-	28162770	PL21	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	-0.12178848039804224	[439]	[175]	-1	hSpCas9	negative selection	10803934
119232456	119232479	11	+	28162770	PL21	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	0.6273518277142661	[353]	[237]	5	hSpCas9	negative selection	10803935
119273918	119273941	11	-	28162770	PL21	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.030214613047007732	[233]	[103]	0	hSpCas9	negative selection	10803936
119278238	119278261	11	+	28162770	PL21	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	1.059787728430355	[506]	[459]	8	hSpCas9	negative selection	10803937
119284981	119285004	11	-	28162770	PL21	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	0.2155696550589261	[92]	[46]	2	hSpCas9	negative selection	10803938
119206564	119206587	11	+	28162770	P31FUJ	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-1.858987367862048	[70]	[22]	-8	hSpCas9	negative selection	10973295
119285258	119285281	11	-	28162770	P31FUJ	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.7061597826587516	[518]	[994]	7	hSpCas9	negative selection	10973296
119271831	119271854	11	+	28162770	P31FUJ	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.47716028784522013	[150]	[246]	5	hSpCas9	negative selection	10973297
119285047	119285070	11	-	28162770	P31FUJ	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.48914195767416413	[128]	[107]	-4	hSpCas9	negative selection	10973298
119285361	119285384	11	-	28162770	P31FUJ	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	0.45907550022328936	[38]	[62]	5	hSpCas9	negative selection	10973299
119285377	119285400	11	-	28162770	P31FUJ	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.16284630975627457	[411]	[541]	1	hSpCas9	negative selection	10973300
119232456	119232479	11	+	28162770	P31FUJ	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.056320134883764084	[560]	[633]	0	hSpCas9	negative selection	10973301
119273918	119273941	11	-	28162770	P31FUJ	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	-0.1370432216089476	[305]	[326]	-1	hSpCas9	negative selection	10973302
119278238	119278261	11	+	28162770	P31FUJ	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.6460453540123368	[657]	[1209]	7	hSpCas9	negative selection	10973303
119284981	119285004	11	-	28162770	P31FUJ	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-0.4958366102481725	[185]	[154]	-4	hSpCas9	negative selection	10973304
119206564	119206587	11	+	28162770	OCIAML5	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	0.48816234076630916	[46]	[118]	4	hSpCas9	negative selection	11142661
119285258	119285281	11	-	28162770	OCIAML5	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	1.3941574413297237	[222]	[1057]	9	hSpCas9	negative selection	11142662
119271831	119271854	11	+	28162770	OCIAML5	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.49107800993306105	[107]	[273]	4	hSpCas9	negative selection	11142663
119285047	119285070	11	-	28162770	OCIAML5	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	1.3833114920669314	[78]	[371]	9	hSpCas9	negative selection	11142664
119285361	119285384	11	-	28162770	OCIAML5	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	0.04101822521949128	[6]	[12]	0	hSpCas9	negative selection	11142665
119285377	119285400	11	-	28162770	OCIAML5	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	1.0501475375350484	[205]	[769]	8	hSpCas9	negative selection	11142666
119232456	119232479	11	+	28162770	OCIAML5	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	1.0637311951100115	[365]	[1380]	8	hSpCas9	negative selection	11142667
119273918	119273941	11	-	28162770	OCIAML5	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	1.4750048272993252	[167]	[842]	9	hSpCas9	negative selection	11142668
119278238	119278261	11	+	28162770	OCIAML5	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	2.766121553390814	[371]	[4567]	9	hSpCas9	negative selection	11142669
119284981	119285004	11	-	28162770	OCIAML5	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	1.0350393727300695	[92]	[343]	8	hSpCas9	negative selection	11142670
119206564	119206587	11	+	28162770	EOL1	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-0.465398746745479	[151]	[57]	-3	hSpCas9	negative selection	11312027
119285258	119285281	11	-	28162770	EOL1	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	1.2430120111543255	[416]	[519]	9	hSpCas9	negative selection	11312028
119271831	119271854	11	+	28162770	EOL1	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	-0.14277525327307994	[328]	[156]	-1	hSpCas9	negative selection	11312029
119285047	119285070	11	-	28162770	EOL1	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	1.4503046828929684	[256]	[369]	9	hSpCas9	negative selection	11312030
119285361	119285384	11	-	28162770	EOL1	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	1.4666971887527176	[56]	[82]	9	hSpCas9	negative selection	11312031
119285377	119285400	11	-	28162770	EOL1	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.6892162945265885	[783]	[665]	6	hSpCas9	negative selection	11312032
119232456	119232479	11	+	28162770	EOL1	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	0.4118641799419944	[544]	[381]	4	hSpCas9	negative selection	11312033
119273918	119273941	11	-	28162770	EOL1	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.8409611412975598	[301]	[284]	7	hSpCas9	negative selection	11312034
119278238	119278261	11	+	28162770	EOL1	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.5314028781405331	[653]	[497]	5	hSpCas9	negative selection	11312035
119284981	119285004	11	-	28162770	EOL1	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-0.06836280364314606	[202]	[101]	0	hSpCas9	negative selection	11312036
119206564	119206587	11	+	28162770	MOLM13	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-3.1526970289072986	[122]	[9]	-8	hSpCas9	negative selection	11481393
119285258	119285281	11	-	28162770	MOLM13	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	-1.3126239282943843	[425]	[123]	-6	hSpCas9	negative selection	11481394
119271831	119271854	11	+	28162770	MOLM13	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	-0.9312065738652435	[239]	[90]	-5	hSpCas9	negative selection	11481395
119285047	119285070	11	-	28162770	MOLM13	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.2047486375174309	[211]	[132]	-1	hSpCas9	negative selection	11481396
119285361	119285384	11	-	28162770	MOLM13	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	1.6563344709576888	[42]	[97]	9	hSpCas9	negative selection	11481397
119285377	119285400	11	-	28162770	MOLM13	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	-0.6501663799771336	[559]	[257]	-4	hSpCas9	negative selection	11481398
119232456	119232479	11	+	28162770	MOLM13	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-2.9890178356771724	[570]	[51]	-8	hSpCas9	negative selection	11481399
119273918	119273941	11	-	28162770	MOLM13	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	-2.002252717174719	[337]	[60]	-7	hSpCas9	negative selection	11481400
119278238	119278261	11	+	28162770	MOLM13	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	-1.867606478301996	[640]	[126]	-7	hSpCas9	negative selection	11481401
119284981	119285004	11	-	28162770	MOLM13	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-3.055672574512434	[183]	[15]	-8	hSpCas9	negative selection	11481402
119206564	119206587	11	+	28162770	HEL	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-1.0353330731122807	[111]	[34]	-6	hSpCas9	negative selection	11650759
119285258	119285281	11	-	28162770	HEL	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.3217958481385623	[365]	[292]	2	hSpCas9	negative selection	11650760
119271831	119271854	11	+	28162770	HEL	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.45179604928896155	[241]	[211]	4	hSpCas9	negative selection	11650761
119285047	119285070	11	-	28162770	HEL	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.7059893222307205	[162]	[63]	-4	hSpCas9	negative selection	11650762
119285361	119285384	11	-	28162770	HEL	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	1.6427388320003569	[26]	[53]	9	hSpCas9	negative selection	11650763
119285377	119285400	11	-	28162770	HEL	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	-0.23604758103056267	[501]	[272]	-2	hSpCas9	negative selection	11650764
119232456	119232479	11	+	28162770	HEL	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	0.18913367646202572	[555]	[405]	1	hSpCas9	negative selection	11650765
119273918	119273941	11	-	28162770	HEL	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.1514907661013946	[297]	[211]	1	hSpCas9	negative selection	11650766
119278238	119278261	11	+	28162770	HEL	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	1.4797854389947662	[528]	[944]	9	hSpCas9	negative selection	11650767
119284981	119285004	11	-	28162770	HEL	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	-0.630909247858289	[190]	[78]	-4	hSpCas9	negative selection	11650768
119206564	119206587	11	+	28162770	MV411	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	0.1959072501426935	[56]	[54]	1	hSpCas9	negative selection	11820125
119285258	119285281	11	-	28162770	MV411	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.7166617364376598	[306]	[424]	6	hSpCas9	negative selection	11820126
119271831	119271854	11	+	28162770	MV411	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	1.1294742134284856	[120]	[222]	8	hSpCas9	negative selection	11820127
119285047	119285070	11	-	28162770	MV411	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.10925596226526357	[104]	[81]	-1	hSpCas9	negative selection	11820128
119285361	119285384	11	-	28162770	MV411	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	-0.8568991090319606	[42]	[19]	-5	hSpCas9	negative selection	11820129
119285377	119285400	11	-	28162770	MV411	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	-0.10020493608367387	[466]	[366]	-1	hSpCas9	negative selection	11820130
119232456	119232479	11	+	28162770	MV411	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	0.23982436667290008	[379]	[377]	2	hSpCas9	negative selection	11820131
119273918	119273941	11	-	28162770	MV411	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.3656189771310895	[245]	[266]	3	hSpCas9	negative selection	11820132
119278238	119278261	11	+	28162770	MV411	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	1.6458959772310409	[546]	[1441]	9	hSpCas9	negative selection	11820133
119284981	119285004	11	-	28162770	MV411	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	0.0002198504117565392	[126]	[106]	0	hSpCas9	negative selection	11820134
119206564	119206587	11	+	28162770	MONOMAC1	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-0.07839235056093452	[34]	[37]	0	hSpCas9	negative selection	11989491
119285258	119285281	11	-	28162770	MONOMAC1	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.28497935194803625	[241]	[337]	3	hSpCas9	negative selection	11989492
119271831	119271854	11	+	28162770	MONOMAC1	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.4614546890835678	[101]	[160]	4	hSpCas9	negative selection	11989493
119285047	119285070	11	-	28162770	MONOMAC1	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.04503375361450368	[62]	[69]	0	hSpCas9	negative selection	11989494
119285361	119285384	11	-	28162770	MONOMAC1	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	-3.197036847059554	[15]	[1]	-9	hSpCas9	negative selection	11989495
119285377	119285400	11	-	28162770	MONOMAC1	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.01988563391992826	[301]	[350]	0	hSpCas9	negative selection	11989496
119232456	119232479	11	+	28162770	MONOMAC1	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.08062735494424322	[237]	[257]	0	hSpCas9	negative selection	11989497
119273918	119273941	11	-	28162770	MONOMAC1	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	-1.1312824015758394	[192]	[100]	-7	hSpCas9	negative selection	11989498
119278238	119278261	11	+	28162770	MONOMAC1	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	1.90477426563218	[358]	[1540]	9	hSpCas9	negative selection	11989499
119284981	119285004	11	-	28162770	MONOMAC1	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	0.2914628141603113	[66]	[93]	3	hSpCas9	negative selection	11989500
119206564	119206587	11	+	28162770	OCIAML2	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-1.0921182019884315	[9]	[25]	-6	hSpCas9	negative selection	12158857
119285258	119285281	11	-	28162770	OCIAML2	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	-0.04213006615675474	[59]	[322]	0	hSpCas9	negative selection	12158858
119271831	119271854	11	+	28162770	OCIAML2	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	0.1081541005498706	[38]	[232]	1	hSpCas9	negative selection	12158859
119285047	119285070	11	-	28162770	OCIAML2	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	-0.08421300390308525	[34]	[182]	0	hSpCas9	negative selection	12158860
119285361	119285384	11	-	28162770	OCIAML2	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	-0.47062982524216124	[10]	[43]	-4	hSpCas9	negative selection	12158861
119285377	119285400	11	-	28162770	OCIAML2	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.7543365397581131	[59]	[560]	7	hSpCas9	negative selection	12158862
119232456	119232479	11	+	28162770	OCIAML2	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	-0.09717142971471682	[65]	[341]	-1	hSpCas9	negative selection	12158863
119273918	119273941	11	-	28162770	OCIAML2	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.7152367200691729	[29]	[272]	7	hSpCas9	negative selection	12158864
119278238	119278261	11	+	28162770	OCIAML2	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	0.40311848574372755	[90]	[666]	4	hSpCas9	negative selection	12158865
119284981	119285004	11	-	28162770	OCIAML2	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	1.3452871103188668	[11]	[168]	9	hSpCas9	negative selection	12158866
119206564	119206587	11	+	28162770	OCIAML3	viability	GACGGTGGACAAGAAGATGGTGG	CBL	ENSG00000110395	-0.8803118254808044	[24]	[40]	-6	hSpCas9	negative selection	12328223
119285258	119285281	11	-	28162770	OCIAML3	viability	TATGGCCGGTCTGGAGGCGGTGG	CBL	ENSG00000110395	0.18301620576379862	[102]	[352]	1	hSpCas9	negative selection	12328224
119271831	119271854	11	+	28162770	OCIAML3	viability	GATTACTAAAGCAGATGCTGCGG	CBL	ENSG00000110395	-0.7223317372997027	[46]	[85]	-5	hSpCas9	negative selection	12328225
119285047	119285070	11	-	28162770	OCIAML3	viability	GAGGGAACACATACTCGCTGCGG	CBL	ENSG00000110395	0.16498426017204199	[38]	[131]	1	hSpCas9	negative selection	12328226
119285361	119285384	11	-	28162770	OCIAML3	viability	AAGGCGGCTAGAGGGGACAGGGG	CBL	ENSG00000110395	3.3946770464480025	[3]	[126]	9	hSpCas9	negative selection	12328227
119285377	119285400	11	-	28162770	OCIAML3	viability	GCAGCCATGAGTCTCCAAGGCGG	CBL	ENSG00000110395	0.7603419322555767	[131]	[674]	6	hSpCas9	negative selection	12328228
119232456	119232479	11	+	28162770	OCIAML3	viability	GTTGTGTCAGAACCCAAAGCTGG	CBL	ENSG00000110395	0.8389517669519428	[119]	[647]	7	hSpCas9	negative selection	12328229
119273918	119273941	11	-	28162770	OCIAML3	viability	GGCCTCCAGCCCAGAACTGATGG	CBL	ENSG00000110395	0.4934552009261763	[63]	[271]	4	hSpCas9	negative selection	12328230
119278238	119278261	11	+	28162770	OCIAML3	viability	GATGTAAAGATTGAGCCCTGTGG	CBL	ENSG00000110395	1.1047747599541553	[133]	[869]	8	hSpCas9	negative selection	12328231
119284981	119285004	11	-	28162770	OCIAML3	viability	GGGGCCATGGAGAATGGAGAAGG	CBL	ENSG00000110395	0.4059923596758369	[33]	[135]	4	hSpCas9	negative selection	12328232