Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:54567
• Symbol:DLL4
• Description:delta like canonical Notch ligand 4

DataSource: http://genomecrispr.dkfz.de/#!/results/DLL4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
40930043	40930066	15	-	26472758	Jiyoye	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.11219877758770593	[128]	[89]	-1	hSpCas9	negative selection	44685
40936568	40936591	15	-	26472758	Jiyoye	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.28989748553682015	[106]	[65]	-2	hSpCas9	negative selection	44686
40936529	40936552	15	+	26472758	Jiyoye	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.1479325548344536	[151]	[126]	1	hSpCas9	negative selection	44687
40929691	40929714	15	-	26472758	Jiyoye	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.762270340328435	[171]	[219]	5	hSpCas9	negative selection	44688
40929954	40929977	15	-	26472758	Jiyoye	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.4841373633207577	[72]	[76]	3	hSpCas9	negative selection	44689
40929998	40930021	15	-	26472758	Jiyoye	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.16838852191875686	[58]	[49]	1	hSpCas9	negative selection	44690
40931596	40931619	15	-	26472758	Jiyoye	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-1.0134003013144004	[347]	[129]	-6	hSpCas9	negative selection	44691
40935004	40935027	15	+	26472758	Jiyoye	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	-0.16638235594303352	[188]	[126]	-1	hSpCas9	negative selection	44692
40936465	40936488	15	-	26472758	Jiyoye	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	0.4071753815058734	[43]	[43]	3	hSpCas9	negative selection	44693
40936546	40936569	15	-	26472758	Jiyoye	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	44694
40930043	40930066	15	-	26472758	KBM7	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.06167020049911971	[488,484]	[184,251]	0	hSpCas9	negative selection	235803
40936568	40936591	15	-	26472758	KBM7	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	0.01961630397568792	[261,272]	[139,117]	0	hSpCas9	negative selection	235804
40936529	40936552	15	+	26472758	KBM7	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	-0.17529051397669934	[708,393]	[241,207]	-2	hSpCas9	negative selection	235805
40929691	40929714	15	-	26472758	KBM7	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.155181212732665	[748,487]	[307,210]	-1	hSpCas9	negative selection	235806
40929954	40929977	15	-	26472758	KBM7	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.6682202453871257	[270,262]	[215,185]	7	hSpCas9	negative selection	235807
40929998	40930021	15	-	26472758	KBM7	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	-1.313273609093932	[107,187]	[39,18]	-7	hSpCas9	negative selection	235808
40931596	40931619	15	-	26472758	KBM7	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.17093024899082687	[1073,1071]	[293,589]	-2	hSpCas9	negative selection	235809
40935004	40935027	15	+	26472758	KBM7	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.638625687755714	[838,665]	[517,572]	7	hSpCas9	negative selection	235810
40936465	40936488	15	-	26472758	KBM7	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.010727931206917507	[117,205]	[104,53]	0	hSpCas9	negative selection	235811
40936546	40936569	15	-	26472758	KBM7	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	2.6365197428611475	[5,29]	[56,55]	9	hSpCas9	negative selection	235812
40930043	40930066	15	-	26472758	Raji	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.26417532723836334	[206]	[39]	-2	hSpCas9	negative selection	426921
40936568	40936591	15	-	26472758	Raji	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-1.062541466068713	[143]	[15]	-7	hSpCas9	negative selection	426922
40936529	40936552	15	+	26472758	Raji	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.08748397793589457	[291]	[71]	0	hSpCas9	negative selection	426923
40929691	40929714	15	-	26472758	Raji	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.1715924143292159	[363]	[74]	-1	hSpCas9	negative selection	426924
40929954	40929977	15	-	26472758	Raji	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.4944066584828469	[155]	[50]	5	hSpCas9	negative selection	426925
40929998	40930021	15	-	26472758	Raji	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.7240548958220936	[59]	[22]	6	hSpCas9	negative selection	426926
40931596	40931619	15	-	26472758	Raji	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.29471490819774604	[665]	[125]	-2	hSpCas9	negative selection	426927
40935004	40935027	15	+	26472758	Raji	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	-0.16922056900427251	[469]	[96]	-1	hSpCas9	negative selection	426928
40936465	40936488	15	-	26472758	Raji	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.8082242773360278	[82]	[10]	-6	hSpCas9	negative selection	426929
40936546	40936569	15	-	26472758	Raji	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	-0.47757896534755684	[35]	[5]	-4	hSpCas9	negative selection	426930
40930043	40930066	15	-	26472758	K562	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	0.3960583760810096	[396]	[440]	3	hSpCas9	negative selection	618039
40936568	40936591	15	-	26472758	K562	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.5109589036136397	[183]	[108]	-3	hSpCas9	negative selection	618040
40936529	40936552	15	+	26472758	K562	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.3191160949440481	[413]	[435]	2	hSpCas9	negative selection	618041
40929691	40929714	15	-	26472758	K562	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.13317035796175883	[468]	[360]	-1	hSpCas9	negative selection	618042
40929954	40929977	15	-	26472758	K562	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.5210727427893685	[245]	[297]	4	hSpCas9	negative selection	618043
40929998	40930021	15	-	26472758	K562	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	-1.013893267924944	[121]	[50]	-5	hSpCas9	negative selection	618044
40931596	40931619	15	-	26472758	K562	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.3336177153890365	[1038]	[695]	-2	hSpCas9	negative selection	618045
40935004	40935027	15	+	26472758	K562	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.46214071746889346	[441]	[513]	3	hSpCas9	negative selection	618046
40936465	40936488	15	-	26472758	K562	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-4.215012890970851	[131]	[5]	-9	hSpCas9	negative selection	618047
40936546	40936569	15	-	26472758	K562	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	0.3375281320579284	[29]	[31]	2	hSpCas9	negative selection	618048
40929691	40929714	15	-	26627737	DLD1	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.11276170114445438	[1022]	[408,352,284]	1	hSpCas9	negative selection	790491
40929854	40929877	15	-	26627737	DLD1	viability	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-1.1262314454700906	[727]	[100,177,45]	-7	hSpCas9	negative selection	790492
40930672	40930695	15	-	26627737	DLD1	viability	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.5823097129768713	[257]	[63,203,100]	6	hSpCas9	negative selection	790493
40931506	40931529	15	-	26627737	DLD1	viability	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-1.3755801352211132	[322]	[51,70,0]	-8	hSpCas9	negative selection	790494
40932182	40932205	15	+	26627737	DLD1	viability	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.8581747221951999	[615]	[250,522,289]	8	hSpCas9	negative selection	790495
40932338	40932361	15	-	26627737	DLD1	viability	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.4842956680175518	[500]	[251,197,207]	5	hSpCas9	negative selection	790496
40929691	40929714	15	-	26627737	GBM cells	viability after 5 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.11579415563522566	[486]	[308,256]	1	hSpCas9	negative selection	872806
40929854	40929877	15	-	26627737	GBM cells	viability after 5 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.08230891808368604	[228]	[150,80]	-1	hSpCas9	negative selection	872807
40930672	40930695	15	-	26627737	GBM cells	viability after 5 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.03166908373745714	[82]	[69,20]	0	hSpCas9	negative selection	872808
40931506	40931529	15	-	26627737	GBM cells	viability after 5 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.6403808612868325	[63]	[40,65]	8	hSpCas9	negative selection	872809
40932182	40932205	15	+	26627737	GBM cells	viability after 5 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.2399507927207527	[389]	[220,272]	4	hSpCas9	negative selection	872810
40932338	40932361	15	-	26627737	GBM cells	viability after 5 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.0015504515633997934	[251]	[133,135]	0	hSpCas9	negative selection	872811
40929691	40929714	15	-	26627737	GBM cells	viability after 13 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.1317813416858874	[486]	[342,245]	1	hSpCas9	negative selection	955121
40929854	40929877	15	-	26627737	GBM cells	viability after 13 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.21464261189654593	[228]	[116,98]	-3	hSpCas9	negative selection	955122
40930672	40930695	15	-	26627737	GBM cells	viability after 13 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.2953502024012391	[82]	[105,13]	4	hSpCas9	negative selection	955123
40931506	40931529	15	-	26627737	GBM cells	viability after 13 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.5690155551301712	[63]	[45,55]	7	hSpCas9	negative selection	955124
40932182	40932205	15	+	26627737	GBM cells	viability after 13 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.6721643239212086	[389]	[361,316]	7	hSpCas9	negative selection	955125
40932338	40932361	15	-	26627737	GBM cells	viability after 13 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.36355827852251915	[251]	[97,112]	-4	hSpCas9	negative selection	955126
40929691	40929714	15	-	26627737	GBM cells	viability after 21 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.21601145712569358	[486]	[299,313]	2	hSpCas9	negative selection	1037436
40929854	40929877	15	-	26627737	GBM cells	viability after 21 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.5480716399607997	[228]	[82,86]	-5	hSpCas9	negative selection	1037437
40930672	40930695	15	-	26627737	GBM cells	viability after 21 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-3.527227609423644	[82]	[5,1]	-9	hSpCas9	negative selection	1037438
40931506	40931529	15	-	26627737	GBM cells	viability after 21 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.8211830596378533	[63]	[62,59]	7	hSpCas9	negative selection	1037439
40932182	40932205	15	+	26627737	GBM cells	viability after 21 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	1.0477266430507366	[389]	[472,405]	9	hSpCas9	negative selection	1037440
40932338	40932361	15	-	26627737	GBM cells	viability after 21 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.09442390783931866	[251]	[153,138]	1	hSpCas9	negative selection	1037441
40929691	40929714	15	-	26627737	RPE1	viability after 9 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-1.1063298923285856	[1584]	[188,283]	-7	hSpCas9	negative selection	1119751
40929854	40929877	15	-	26627737	RPE1	viability after 9 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-2.178422926669051	[1709]	[95,146]	-9	hSpCas9	negative selection	1119752
40930672	40930695	15	-	26627737	RPE1	viability after 9 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.7225685662907577	[388]	[117,307]	5	hSpCas9	negative selection	1119753
40931506	40931529	15	-	26627737	RPE1	viability after 9 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.16736076126696064	[420]	[61,258]	1	hSpCas9	negative selection	1119754
40932182	40932205	15	+	26627737	RPE1	viability after 9 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	1.499366341566129	[1154]	[858,1232]	8	hSpCas9	negative selection	1119755
40932338	40932361	15	-	26627737	RPE1	viability after 9 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.19054952363046573	[1075]	[292,297]	-1	hSpCas9	negative selection	1119756
40929691	40929714	15	-	26627737	RPE1	viability after 12 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.9293793353978038	[1584]	[192,255]	-6	hSpCas9	negative selection	1202066
40929854	40929877	15	-	26627737	RPE1	viability after 12 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-3.1858658904934716	[1709]	[83,14]	-9	hSpCas9	negative selection	1202067
40930672	40930695	15	-	26627737	RPE1	viability after 12 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.07534290603770033	[388]	[45,177]	0	hSpCas9	negative selection	1202068
40931506	40931529	15	-	26627737	RPE1	viability after 12 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.38454232635570007	[420]	[33,267]	2	hSpCas9	negative selection	1202069
40932182	40932205	15	+	26627737	RPE1	viability after 12 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	1.4844128393636034	[1154]	[876,858]	7	hSpCas9	negative selection	1202070
40932338	40932361	15	-	26627737	RPE1	viability after 12 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.2812261246882345	[1075]	[250,223]	-2	hSpCas9	negative selection	1202071
40929691	40929714	15	-	26627737	RPE1	viability after 15 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.8273965713925057	[1584]	[242,261]	-5	hSpCas9	negative selection	1284381
40929854	40929877	15	-	26627737	RPE1	viability after 15 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-2.07543963378722	[1709]	[183,47]	-8	hSpCas9	negative selection	1284382
40930672	40930695	15	-	26627737	RPE1	viability after 15 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.0680900985287134	[388]	[38,188]	0	hSpCas9	negative selection	1284383
40931506	40931529	15	-	26627737	RPE1	viability after 15 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.24840771598200118	[420]	[86,193]	1	hSpCas9	negative selection	1284384
40932182	40932205	15	+	26627737	RPE1	viability after 15 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	1.6211359633667781	[1154]	[1057,953]	8	hSpCas9	negative selection	1284385
40932338	40932361	15	-	26627737	RPE1	viability after 15 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.1306784905027979	[1075]	[276,278]	-1	hSpCas9	negative selection	1284386
40929691	40929714	15	-	26627737	RPE1	viability after 18 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-1.3940536232691887	[1584]	[140,185]	-7	hSpCas9	negative selection	1366696
40929854	40929877	15	-	26627737	RPE1	viability after 18 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-5.349624417114898	[1709]	[5,16]	-9	hSpCas9	negative selection	1366697
40930672	40930695	15	-	26627737	RPE1	viability after 18 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.28058303357204917	[388]	[25,235]	1	hSpCas9	negative selection	1366698
40931506	40931529	15	-	26627737	RPE1	viability after 18 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.011165767105048907	[420]	[26,207]	0	hSpCas9	negative selection	1366699
40932182	40932205	15	+	26627737	RPE1	viability after 18 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	1.623949670480508	[1154]	[893,1031]	8	hSpCas9	negative selection	1366700
40932338	40932361	15	-	26627737	RPE1	viability after 18 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.6835356714332197	[1075]	[174,186]	-4	hSpCas9	negative selection	1366701
40929691	40929714	15	-	26627737	HeLa	viability after 8 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.21292409531838163	[659]	[463,386,186]	2	hSpCas9	negative selection	1449011
40929854	40929877	15	-	26627737	HeLa	viability after 8 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.7589925503277871	[578]	[118,289,38]	-6	hSpCas9	negative selection	1449012
40930672	40930695	15	-	26627737	HeLa	viability after 8 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.6114906105326783	[186]	[93,202,72]	5	hSpCas9	negative selection	1449013
40931506	40931529	15	-	26627737	HeLa	viability after 8 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.4415432523891232	[137]	[58,88,90]	4	hSpCas9	negative selection	1449014
40932182	40932205	15	+	26627737	HeLa	viability after 8 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.5160394465778085	[714]	[520,259,561]	4	hSpCas9	negative selection	1449015
40932338	40932361	15	-	26627737	HeLa	viability after 8 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.7260602351687844	[434]	[80,96,154]	-6	hSpCas9	negative selection	1449016
40929691	40929714	15	-	26627737	HeLa	viability after 12 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.2934710896528604	[659]	[319,328,353]	2	hSpCas9	negative selection	1531326
40929854	40929877	15	-	26627737	HeLa	viability after 12 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.836291024867903	[578]	[154,177,64]	-6	hSpCas9	negative selection	1531327
40930672	40930695	15	-	26627737	HeLa	viability after 12 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-1.0315278238199994	[186]	[41,23,48]	-7	hSpCas9	negative selection	1531328
40931506	40931529	15	-	26627737	HeLa	viability after 12 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	1.3606703080352687	[137]	[172,194,66]	8	hSpCas9	negative selection	1531329
40932182	40932205	15	+	26627737	HeLa	viability after 12 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.3510781574575649	[714]	[442,325,368]	3	hSpCas9	negative selection	1531330
40932338	40932361	15	-	26627737	HeLa	viability after 12 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.08105709666301006	[434]	[301,130,146]	0	hSpCas9	negative selection	1531331
40929691	40929714	15	-	26627737	HeLa	viability after 15 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.6160478189305995	[659]	[563,371,287]	5	hSpCas9	negative selection	1613641
40929854	40929877	15	-	26627737	HeLa	viability after 15 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.5777920657166182	[578]	[113,121,244]	-5	hSpCas9	negative selection	1613642
40930672	40930695	15	-	26627737	HeLa	viability after 15 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.9421432450263926	[186]	[96,261,74]	7	hSpCas9	negative selection	1613643
40931506	40931529	15	-	26627737	HeLa	viability after 15 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.6644552574375108	[137]	[62,108,95]	5	hSpCas9	negative selection	1613644
40932182	40932205	15	+	26627737	HeLa	viability after 15 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.2768690092567919	[714]	[411,270,375]	2	hSpCas9	negative selection	1613645
40932338	40932361	15	-	26627737	HeLa	viability after 15 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.041246349795101056	[434]	[242,58,248]	0	hSpCas9	negative selection	1613646
40929691	40929714	15	-	26627737	HeLa	viability after 18 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.6253003062151848	[659]	[369,324,287]	5	hSpCas9	negative selection	1695956
40929854	40929877	15	-	26627737	HeLa	viability after 18 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.5023350352035282	[578]	[88,105,244]	-4	hSpCas9	negative selection	1695957
40930672	40930695	15	-	26627737	HeLa	viability after 18 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.9225496920709714	[186]	[65,210,74]	7	hSpCas9	negative selection	1695958
40931506	40931529	15	-	26627737	HeLa	viability after 18 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.6588236583225754	[137]	[40,90,95]	5	hSpCas9	negative selection	1695959
40932182	40932205	15	+	26627737	HeLa	viability after 18 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.3040473768136088	[714]	[284,229,375]	2	hSpCas9	negative selection	1695960
40932338	40932361	15	-	26627737	HeLa	viability after 18 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.06655125646271162	[434]	[165,52,248]	0	hSpCas9	negative selection	1695961
40929691	40929714	15	-	26627737	HCT116	viability after 6 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-1.2219472137905947	[1106]	[33,96]	-6	hSpCas9	negative selection	1778271
40929854	40929877	15	-	26627737	HCT116	viability after 6 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-1.6169018748030692	[647]	[87,2]	-7	hSpCas9	negative selection	1778272
40930672	40930695	15	-	26627737	HCT116	viability after 6 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.7255557803745778	[214]	[42,7]	-4	hSpCas9	negative selection	1778273
40931506	40931529	15	-	26627737	HCT116	viability after 6 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.6093824635478385	[255]	[72,54]	3	hSpCas9	negative selection	1778274
40932182	40932205	15	+	26627737	HCT116	viability after 6 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	-0.7505972376932954	[1158]	[77,124]	-4	hSpCas9	negative selection	1778275
40932338	40932361	15	-	26627737	HCT116	viability after 6 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.7001058837162256	[617]	[55,213]	4	hSpCas9	negative selection	1778276
40929691	40929714	15	-	26627737	HCT116	viability after 8 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.9240586379655144	[887]	[200,344,226]	-8	hSpCas9	negative selection	1860586
40929854	40929877	15	-	26627737	HCT116	viability after 8 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.9248234438367786	[366]	[113,123,81]	-8	hSpCas9	negative selection	1860587
40930672	40930695	15	-	26627737	HCT116	viability after 8 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.09569108122605341	[210]	[106,78,139]	-1	hSpCas9	negative selection	1860588
40931506	40931529	15	-	26627737	HCT116	viability after 8 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	2.6038413490790475	[19]	[101,64,34]	9	hSpCas9	negative selection	1860589
40932182	40932205	15	+	26627737	HCT116	viability after 8 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	-0.19791753254284905	[741]	[344,355,367]	-2	hSpCas9	negative selection	1860590
40932338	40932361	15	-	26627737	HCT116	viability after 8 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.08785803138303205	[285]	[207,111,182]	1	hSpCas9	negative selection	1860591
40929691	40929714	15	-	26627737	HCT116	viability after 9 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.8516422791004006	[1106]	[303,52]	-5	hSpCas9	negative selection	1942901
40929854	40929877	15	-	26627737	HCT116	viability after 9 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	0.507125873437028	[647]	[179,297]	4	hSpCas9	negative selection	1942902
40930672	40930695	15	-	26627737	HCT116	viability after 9 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	1.7686525462002245	[214]	[184,203]	9	hSpCas9	negative selection	1942903
40931506	40931529	15	-	26627737	HCT116	viability after 9 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	0.29916279071071084	[255]	[125,50]	2	hSpCas9	negative selection	1942904
40932182	40932205	15	+	26627737	HCT116	viability after 9 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	-0.9339855056012994	[1158]	[247,93]	-6	hSpCas9	negative selection	1942905
40932338	40932361	15	-	26627737	HCT116	viability after 9 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.4965968525122715	[617]	[100,336]	3	hSpCas9	negative selection	1942906
40929691	40929714	15	-	26627737	HCT116	viability after 12 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-1.3174684351415753	[887]	[145,254,165]	-8	hSpCas9	negative selection	2025216
40929854	40929877	15	-	26627737	HCT116	viability after 12 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.33923629694735086	[366]	[189,190,73]	-4	hSpCas9	negative selection	2025217
40930672	40930695	15	-	26627737	HCT116	viability after 12 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.5473189615340764	[210]	[153,43,21]	-5	hSpCas9	negative selection	2025218
40931506	40931529	15	-	26627737	HCT116	viability after 12 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	3.527670371036557	[19]	[185,122,48]	9	hSpCas9	negative selection	2025219
40932182	40932205	15	+	26627737	HCT116	viability after 12 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.060496322085910936	[741]	[365,468,389]	0	hSpCas9	negative selection	2025220
40932338	40932361	15	-	26627737	HCT116	viability after 12 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.4923693011314181	[285]	[170,175,289]	5	hSpCas9	negative selection	2025221
40929691	40929714	15	-	26627737	HCT116	viability after 15 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.8588032789610864	[887]	[302,322,220]	-7	hSpCas9	negative selection	2107531
40929854	40929877	15	-	26627737	HCT116	viability after 15 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.049490544951045656	[366]	[254,222,139]	0	hSpCas9	negative selection	2107532
40930672	40930695	15	-	26627737	HCT116	viability after 15 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.29599197843123726	[210]	[87,124,81]	-3	hSpCas9	negative selection	2107533
40931506	40931529	15	-	26627737	HCT116	viability after 15 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	2.849729634717658	[19]	[133,68,51]	9	hSpCas9	negative selection	2107534
40932182	40932205	15	+	26627737	HCT116	viability after 15 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.01920084083001794	[741]	[625,332,360]	0	hSpCas9	negative selection	2107535
40932338	40932361	15	-	26627737	HCT116	viability after 15 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.5379892117393024	[285]	[272,237,208]	5	hSpCas9	negative selection	2107536
40929691	40929714	15	-	26627737	HCT116	viability after 18 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.1702964348887539	[887]	[438,447,246]	-1	hSpCas9	negative selection	2189846
40929854	40929877	15	-	26627737	HCT116	viability after 18 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.32555202797287697	[366]	[110,74,247]	-3	hSpCas9	negative selection	2189847
40930672	40930695	15	-	26627737	HCT116	viability after 18 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.3449205478382187	[210]	[134,65,38]	-3	hSpCas9	negative selection	2189848
40931506	40931529	15	-	26627737	HCT116	viability after 18 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	3.7335065770193205	[19]	[96,45,253]	9	hSpCas9	negative selection	2189849
40932182	40932205	15	+	26627737	HCT116	viability after 18 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.2604432510409709	[741]	[347,540,390]	2	hSpCas9	negative selection	2189850
40932338	40932361	15	-	26627737	HCT116	viability after 18 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.9781133728212363	[285]	[382,167,272]	7	hSpCas9	negative selection	2189851
40929961	40929984	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGCCTTAAGCACTTCCAGGCGG	DLL4	ENSG00000128917	0.025547928922289964	[4,4]	[4,3]	0	hSpCas9	positive selection	2983733
40931737	40931760	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAATATTCCCCAGTCCAACCGG	DLL4	ENSG00000128917	-0.17140385357726234	[3,3]	[3,2]	-2	hSpCas9	positive selection	2983734
40929954	40929977	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	-0.01016971742805145	[2,2]	[3,0]	0	hSpCas9	positive selection	2983735
40929832	40929855	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCCCTGTGCAATAGCGCGCGG	DLL4	ENSG00000128917	-0.001765204036515755	[4,4]	[3,3]	0	hSpCas9	positive selection	2983736
40929961	40929984	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGCCTTAAGCACTTCCAGGCGG	DLL4	ENSG00000128917	-0.0614746081714454	[4,4]	[4,1]	-1	hSpCas9	positive selection	3051591
40931737	40931760	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAATATTCCCCAGTCCAACCGG	DLL4	ENSG00000128917	0.10817474005783564	[3,3]	[3,2]	2	hSpCas9	positive selection	3051592
40929954	40929977	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.4582125613574112	[2,2]	[1,2]	7	hSpCas9	positive selection	3051593
40929832	40929855	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCCCTGTGCAATAGCGCGCGG	DLL4	ENSG00000128917	-0.2760795927305023	[4,4]	[4,0]	-4	hSpCas9	positive selection	3051594
40930656	40930679		+	24336571	A375	resistance to PLX after 7 days	ACGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.062403193623894224	[11,15]	[13,14]	2	hSpCas9	positive selection	3109959
40929891	40929914		+	24336571	A375	resistance to PLX after 7 days	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.07929116690084442	[8,8]	[7,9]	2	hSpCas9	positive selection	3109960
40929975	40929998		-	24336571	A375	resistance to PLX after 7 days	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	-0.6505266015050698	[9,7]	[5,4]	-9	hSpCas9	positive selection	3109961
40930632	40930655		+	24336571	A375	resistance to PLX after 7 days	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.10228235103451866	[18,18]	[16,16]	-3	hSpCas9	positive selection	3109962
40930656	40930679		+	24336571	A375	resistance to PLX after 14 days	ACGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.805577094644691	[11,13]	[3,1]	-8	hSpCas9	positive selection	3167752
40929891	40929914		+	24336571	A375	resistance to PLX after 14 days	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.7389035413690832	[10,6]	[5,7]	6	hSpCas9	positive selection	3167753
40929975	40929998		-	24336571	A375	resistance to PLX after 14 days	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.5600347894060997	[6,9]	[4,5]	5	hSpCas9	positive selection	3167754
40930632	40930655		+	24336571	A375	resistance to PLX after 14 days	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.38834748138953024	[18,18]	[5,6]	-4	hSpCas9	positive selection	3167755
40930656	40930679		+	24336571	A375	viability after 7 days	ACGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.10425455691149112	[13]	[11,15]	1	hSpCas9	negative selection	3225545
40929891	40929914		+	24336571	A375	viability after 7 days	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.32273266268777034	[6]	[8,8]	5	hSpCas9	negative selection	3225546
40929975	40929998		-	24336571	A375	viability after 7 days	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.2598175951843815	[7]	[9,7]	4	hSpCas9	negative selection	3225547
40930632	40930655		+	24336571	A375	viability after 7 days	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.19082388423419672	[22]	[18,18]	-3	hSpCas9	negative selection	3225548
40930656	40930679		+	24336571	A375	viability after 14 days	ACGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.035992838692250714	[13]	[11,13]	0	hSpCas9	negative selection	3283338
40929891	40929914		+	24336571	A375	viability after 14 days	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.38494125954929326	[6]	[10,6]	5	hSpCas9	negative selection	3283339
40929975	40929998		-	24336571	A375	viability after 14 days	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.2073039961629617	[7]	[6,9]	2	hSpCas9	negative selection	3283340
40930632	40930655		+	24336571	A375	viability after 14 days	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.16013906745594997	[22]	[18,18]	-2	hSpCas9	negative selection	3283341
40929891	40929914	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	1.7804278220421403	[49,38]	[0,0]	7	hSpCas9	positive selection	3346410
40929975	40929998	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.7058504049511334	[62,124]	[0,0]	3	hSpCas9	positive selection	3346411
40932218	40932241	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-1.2504684287528613	[363,363]	[0,0]	-8	hSpCas9	positive selection	3365608
40932163	40932186	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	-0.12205215562542726	[332,332]	[1,1]	0	hSpCas9	positive selection	3365609
40929960	40929983	15	+	26780180	HT29	viability (Avana library 4 designs)	CTGCCTTAAGCACTTCCAGGCGG	DLL4	ENSG00000128917	0.599561104396543	[]	[]	2	hSpCas9	negative selection	3420500
40931737	40931760	15	-	26780180	HT29	viability (Avana library 4 designs)	GCAATATTCCCCAGTCCAACCGG	DLL4	ENSG00000128917	1.60192390066295	[]	[]	6	hSpCas9	negative selection	3420501
40929954	40929977	15	-	26780180	HT29	viability (Avana library 4 designs)	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	2.2923383435368	[]	[]	8	hSpCas9	negative selection	3420502
40929831	40929854	15	+	26780180	HT29	viability (Avana library 4 designs)	GGTCCCTGTGCAATAGCGCGCGG	DLL4	ENSG00000128917	0.347967506716867	[]	[]	1	hSpCas9	negative selection	3420503
40929831	40929854	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCCCTGTGCAATAGCGCGCGG	DLL4	ENSG00000128917	4.34307225082577	[]	[]	7	hSpCas9	negative selection	3500211
40929954	40929977	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	1.82077474700186	[]	[]	2	hSpCas9	negative selection	3500212
40929960	40929983	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCCTTAAGCACTTCCAGGCGG	DLL4	ENSG00000128917	0.729992175553134	[]	[]	1	hSpCas9	negative selection	3500213
40931737	40931760	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATATTCCCCAGTCCAACCGG	DLL4	ENSG00000128917	1.92321409740659	[]	[]	2	hSpCas9	negative selection	3500214
40934885	40934908	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCTCTCTCCAGGACCAGGAGG	DLL4	ENSG00000128917	1.84362772835633	[]	[]	2	hSpCas9	negative selection	3500215
40929883	40929906	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGGAGTTCATCAACGAGCGCGG	DLL4	ENSG00000128917	5.55470953988106	[]	[]	8	hSpCas9	negative selection	3500216
40929831	40929854	15	+	26780180	A375	viability (Avana lentiGuide)	GGTCCCTGTGCAATAGCGCGCGG	DLL4	ENSG00000128917	-0.5765122715579	[]	[]	-1	hSpCas9	negative selection	3608870
40929954	40929977	15	-	26780180	A375	viability (Avana lentiGuide)	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	-1.90444946610134	[]	[]	-3	hSpCas9	negative selection	3608871
40929960	40929983	15	+	26780180	A375	viability (Avana lentiGuide)	CTGCCTTAAGCACTTCCAGGCGG	DLL4	ENSG00000128917	0.501272751596311	[]	[]	0	hSpCas9	negative selection	3608872
40931737	40931760	15	-	26780180	A375	viability (Avana lentiGuide)	GCAATATTCCCCAGTCCAACCGG	DLL4	ENSG00000128917	0.338043717730773	[]	[]	0	hSpCas9	negative selection	3608873
40934885	40934908	15	+	26780180	A375	viability (Avana lentiGuide)	GGTCTCTCTCCAGGACCAGGAGG	DLL4	ENSG00000128917	-4.02624954473943	[]	[]	-7	hSpCas9	negative selection	3608874
40929883	40929906	15	+	26780180	A375	viability (Avana lentiGuide)	CAGGAGTTCATCAACGAGCGCGG	DLL4	ENSG00000128917	-3.61939414720984	[]	[]	-6	hSpCas9	negative selection	3608875
40929831	40929854	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCCCTGTGCAATAGCGCGCGG	DLL4	ENSG00000128917	0.09764751815300805	[5]	[6,4]	2	hSpCas9	positive selection	3717529
40929954	40929977	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.011290817630984412	[4]	[4,4]	0	hSpCas9	positive selection	3717530
40929960	40929983	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCCTTAAGCACTTCCAGGCGG	DLL4	ENSG00000128917	0.138518031556564	[5]	[6,6]	3	hSpCas9	positive selection	3717531
40931737	40931760	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATATTCCCCAGTCCAACCGG	DLL4	ENSG00000128917	0.20604792407098282	[4]	[4,5]	6	hSpCas9	positive selection	3717532
40934885	40934908	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCTCTCTCCAGGACCAGGAGG	DLL4	ENSG00000128917	0.3571606136131325	[3]	[4,5]	9	hSpCas9	positive selection	3717533
40929883	40929906	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGGAGTTCATCAACGAGCGCGG	DLL4	ENSG00000128917	0.2827465587658863	[5]	[6,6]	7	hSpCas9	positive selection	3717534
40929831	40929854	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCCCTGTGCAATAGCGCGCGG	DLL4	ENSG00000128917	0.1592297945118069	[6]	[6,5]	4	hSpCas9	positive selection	3826136
40929954	40929977	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	-0.7528426975252847	[4]	[2,1]	-7	hSpCas9	positive selection	3826137
40929960	40929983	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCCTTAAGCACTTCCAGGCGG	DLL4	ENSG00000128917	0.08860734660788261	[6]	[6,6]	2	hSpCas9	positive selection	3826138
40931737	40931760	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATATTCCCCAGTCCAACCGG	DLL4	ENSG00000128917	0.308700612204533	[5]	[5,6]	8	hSpCas9	positive selection	3826139
40934885	40934908	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCTCTCTCCAGGACCAGGAGG	DLL4	ENSG00000128917	0.08365020308662009	[5]	[5,3]	1	hSpCas9	positive selection	3826140
40929883	40929906	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGGAGTTCATCAACGAGCGCGG	DLL4	ENSG00000128917	0.14311704858241597	[5]	[5,5]	3	hSpCas9	positive selection	3826141
40930629	40930652	15	-	26780180	A375	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	1.05045121660152	[]	[]	5	hSpCas9	negative selection	3933513
40929891	40929914	15	+	26780180	A375	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.919430208070135	[]	[]	4	hSpCas9	negative selection	3933514
40932218	40932241	15	-	26780180	A375	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	1.68227923279823	[]	[]	9	hSpCas9	negative selection	3933515
40929975	40929998	15	-	26780180	A375	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.751174419060567	[]	[]	2	hSpCas9	negative selection	3933516
40932163	40932186	15	+	26780180	A375	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.737912409191608	[]	[]	2	hSpCas9	negative selection	3933517
40930632	40930655	15	+	26780180	A375	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.531457666883211	[]	[]	1	hSpCas9	negative selection	3933518
40930629	40930652	15	-	26780180	HT29	viability (GeCKOv2 library)	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	1.47144243504913	[]	[]	7	hSpCas9	negative selection	4041479
40929891	40929914	15	+	26780180	HT29	viability (GeCKOv2 library)	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.974804300812917	[]	[]	4	hSpCas9	negative selection	4041480
40932218	40932241	15	-	26780180	HT29	viability (GeCKOv2 library)	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	1.77912514339757	[]	[]	8	hSpCas9	negative selection	4041481
40929975	40929998	15	-	26780180	HT29	viability (GeCKOv2 library)	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.857254099506411	[]	[]	3	hSpCas9	negative selection	4041482
40932163	40932186	15	+	26780180	HT29	viability (GeCKOv2 library)	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.386867346157287	[]	[]	1	hSpCas9	negative selection	4041483
40930632	40930655	15	+	26780180	HT29	viability (GeCKOv2 library)	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.194293002744152	[]	[]	0	hSpCas9	negative selection	4041484
40930656	40930679	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.06316919179871137	[3]	[2,1]	-1	hSpCas9	positive selection	4132456
40929891	40929914	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.0032926777613157543	[2]	[0,2]	0	hSpCas9	positive selection	4132457
40929975	40929998	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.04598689576728593	[2]	[0,2]	1	hSpCas9	positive selection	4132458
40930632	40930655	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.051028794363442764	[4]	[2,2]	-1	hSpCas9	positive selection	4132459
40930656	40930679	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.6316628973018985	[3]	[0,1,1,3]	4	hSpCas9	positive selection	4196478
40929891	40929914	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.7021770463575535	[3]	[0,0,1,0]	-8	hSpCas9	positive selection	4196479
40929975	40929998	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	1.2345966220687037	[4]	[3,3,4,5]	8	hSpCas9	positive selection	4196480
40930632	40930655	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.39711243940776625	[3]	[1,3,4,0]	3	hSpCas9	positive selection	4196481
40929891	40929914	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.10530338380776205	[1]	[1,1]	2	hSpCas9	positive selection	4267055
40929975	40929998	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	-0.0922505163158654	[2]	[2,1]	-2	hSpCas9	positive selection	4267056
40930632	40930655	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3316580679955478	[4]	[3,3]	6	hSpCas9	positive selection	4267057
40930629	40930652	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	0.17315311060225264	[2]	[2,1]	3	hSpCas9	positive selection	4331324
40932218	40932241	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.10416153728544877	[3]	[3,1]	-2	hSpCas9	positive selection	4331325
40932163	40932186	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.3265932495241662	[3]	[3,3]	6	hSpCas9	positive selection	4331326
40929892	40929914	15	+	27760321	OCIAML3	viability	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-1.1993442168661295	[733,636]	[264,190]	-8	hSpCas9	negative selection	4394944
40930006	40930028	15	+	27760321	OCIAML3	viability	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.571773870994468	[968,751]	[941,1059]	6	hSpCas9	negative selection	4394945
40930052	40930074	15	+	27760321	OCIAML3	viability	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-0.006723850352548692	[491,374]	[280,404]	0	hSpCas9	negative selection	4394946
40930633	40930655	15	+	27760321	OCIAML3	viability	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.844206775466652	[663,519]	[842,802]	8	hSpCas9	negative selection	4394947
40930657	40930679	15	+	27760321	OCIAML3	viability	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.15545388214211547	[533,410]	[291,377]	-2	hSpCas9	negative selection	4394948
40929892	40929914	15	+	27760321	OCIAML2	viability	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.38654599015524105	[733,636]	[382,475]	-4	hSpCas9	negative selection	4478407
40930006	40930028	15	+	27760321	OCIAML2	viability	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.04025441493131199	[968,751]	[642,799]	0	hSpCas9	negative selection	4478408
40930052	40930074	15	+	27760321	OCIAML2	viability	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-0.7181330158622187	[491,374]	[198,227]	-6	hSpCas9	negative selection	4478409
40930633	40930655	15	+	27760321	OCIAML2	viability	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.2794082637693775	[663,519]	[525,644]	3	hSpCas9	negative selection	4478410
40930657	40930679	15	+	27760321	OCIAML2	viability	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.0644602137934394	[533,410]	[350,456]	0	hSpCas9	negative selection	4478411
40929892	40929914	15	+	27760321	MV411	viability	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.8247714965694569	[733,636]	[189,351]	-5	hSpCas9	negative selection	4561870
40930006	40930028	15	+	27760321	MV411	viability	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	-0.0877215390805346	[968,751]	[253,945]	0	hSpCas9	negative selection	4561871
40930052	40930074	15	+	27760321	MV411	viability	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-1.0991005312825124	[491,374]	[8,317]	-6	hSpCas9	negative selection	4561872
40930633	40930655	15	+	27760321	MV411	viability	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	1.9056326272604727	[663,519]	[1570,1277]	9	hSpCas9	negative selection	4561873
40930657	40930679	15	+	27760321	MV411	viability	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.4061641515366194	[533,410]	[177,316]	-3	hSpCas9	negative selection	4561874
40929892	40929914	15	+	27760321	HL60	viability	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.35782688439300536	[733,636]	[890,529]	4	hSpCas9	negative selection	4645333
40930006	40930028	15	+	27760321	HL60	viability	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.05797208323238956	[968,751]	[728,723]	0	hSpCas9	negative selection	4645334
40930052	40930074	15	+	27760321	HL60	viability	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	0.00421629003772353	[491,374]	[331,373]	0	hSpCas9	negative selection	4645335
40930633	40930655	15	+	27760321	HL60	viability	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.13925056949876896	[663,519]	[374,500]	-1	hSpCas9	negative selection	4645336
40930657	40930679	15	+	27760321	HL60	viability	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.18606259238393064	[533,410]	[361,309]	-2	hSpCas9	negative selection	4645337
40929892	40929914	15	+	27760321	HT1080	viability	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-1.603400036516819	[636,496]	[112,31]	-5	hSpCas9	negative selection	4728796
40930006	40930028	15	+	27760321	HT1080	viability	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.382100895257795	[751,586]	[222,483]	2	hSpCas9	negative selection	4728797
40930052	40930074	15	+	27760321	HT1080	viability	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	1.0893996221731712	[374,292]	[243,325]	6	hSpCas9	negative selection	4728798
40930633	40930655	15	+	27760321	HT1080	viability	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	1.9447163509596128	[519,405]	[742,673]	8	hSpCas9	negative selection	4728799
40930657	40930679	15	+	27760321	HT1080	viability	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	1.3521847677798666	[410,320]	[503,227]	7	hSpCas9	negative selection	4728800
40929892	40929914	15	+	27760321	HT29	viability after 7 days	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.426909010453724	[636,496]	[558,546,522]	-6	hSpCas9	negative selection	4812259
40930006	40930028	15	+	27760321	HT29	viability after 7 days	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.07125362111720801	[751,586]	[916,999,799]	1	hSpCas9	negative selection	4812260
40930052	40930074	15	+	27760321	HT29	viability after 7 days	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	0.1884844191897841	[374,292]	[384,622,445]	3	hSpCas9	negative selection	4812261
40930633	40930655	15	+	27760321	HT29	viability after 7 days	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.1468125990497107	[519,405]	[695,499,441]	-2	hSpCas9	negative selection	4812262
40930657	40930679	15	+	27760321	HT29	viability after 7 days	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.14911058831413868	[410,320]	[695,277,339]	-2	hSpCas9	negative selection	4812263
40929892	40929914	15	+	27760321	HT29	viability after 25 days	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.04083055702593397	[636,496]	[437,856,602]	0	hSpCas9	negative selection	4895722
40930006	40930028	15	+	27760321	HT29	viability after 25 days	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.1535475823487532	[751,586]	[756,654,1179]	1	hSpCas9	negative selection	4895723
40930052	40930074	15	+	27760321	HT29	viability after 25 days	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-0.2141762196178797	[374,292]	[257,396,336]	-2	hSpCas9	negative selection	4895724
40930633	40930655	15	+	27760321	HT29	viability after 25 days	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.4258930538578013	[519,405]	[782,709,624]	4	hSpCas9	negative selection	4895725
40930657	40930679	15	+	27760321	HT29	viability after 25 days	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.2800587837004444	[410,320]	[593,402,521]	3	hSpCas9	negative selection	4895726
40929892	40929914	15	+	27760321	HT29	viability after 22 days	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.3479006214539058	[636,496]	[325,723,499]	-3	hSpCas9	negative selection	4979185
40930006	40930028	15	+	27760321	HT29	viability after 22 days	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.24894781355869078	[751,586]	[768,896,1098]	2	hSpCas9	negative selection	4979186
40930052	40930074	15	+	27760321	HT29	viability after 22 days	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-0.0010186621737813817	[374,292]	[372,289,495]	0	hSpCas9	negative selection	4979187
40930633	40930655	15	+	27760321	HT29	viability after 22 days	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.4148438629860819	[519,405]	[708,703,727]	4	hSpCas9	negative selection	4979188
40930657	40930679	15	+	27760321	HT29	viability after 22 days	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.24246786829061104	[410,320]	[623,515,356]	2	hSpCas9	negative selection	4979189
40929892	40929914	15	+	27760321	HT29	viability after 19 days	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.2917222861700949	[636,496]	[364,472,725]	-3	hSpCas9	negative selection	5062648
40930006	40930028	15	+	27760321	HT29	viability after 19 days	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	-0.42581853318674634	[751,586]	[612,420,675]	-4	hSpCas9	negative selection	5062649
40930052	40930074	15	+	27760321	HT29	viability after 19 days	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	0.15563056643888237	[374,292]	[343,450,470]	1	hSpCas9	negative selection	5062650
40930633	40930655	15	+	27760321	HT29	viability after 19 days	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.19929668693317648	[519,405]	[665,485,674]	1	hSpCas9	negative selection	5062651
40930657	40930679	15	+	27760321	HT29	viability after 19 days	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.10709851153741506	[410,320]	[678,259,261]	-1	hSpCas9	negative selection	5062652
40929892	40929914	15	+	27760321	HT29	viability after 16 days	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.09555794620981606	[636,496]	[771,568,703]	1	hSpCas9	negative selection	5146111
40930006	40930028	15	+	27760321	HT29	viability after 16 days	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.03987454668515478	[751,586]	[983,662,685]	0	hSpCas9	negative selection	5146112
40930052	40930074	15	+	27760321	HT29	viability after 16 days	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-0.22445232734636456	[374,292]	[273,365,313]	-3	hSpCas9	negative selection	5146113
40930633	40930655	15	+	27760321	HT29	viability after 16 days	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.6195036122188814	[519,405]	[897,875,620]	7	hSpCas9	negative selection	5146114
40930657	40930679	15	+	27760321	HT29	viability after 16 days	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.5853499639184425	[410,320]	[776,518,564]	6	hSpCas9	negative selection	5146115
40929892	40929914	15	+	27760321	HT29	viability after 13 days	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.7750099885090175	[636,496]	[334,327,483]	-7	hSpCas9	negative selection	5229574
40930006	40930028	15	+	27760321	HT29	viability after 13 days	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	-0.19007326644909284	[751,586]	[534,729,771]	-2	hSpCas9	negative selection	5229575
40930052	40930074	15	+	27760321	HT29	viability after 13 days	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-0.4345974756550854	[374,292]	[318,185,350]	-5	hSpCas9	negative selection	5229576
40930633	40930655	15	+	27760321	HT29	viability after 13 days	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3415575667687698	[519,405]	[667,713,660]	4	hSpCas9	negative selection	5229577
40930657	40930679	15	+	27760321	HT29	viability after 13 days	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.22400643137816859	[410,320]	[612,472,406]	2	hSpCas9	negative selection	5229578
40929892	40929914	15	+	27760321	HT29	viability after 10 days	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.6879842049341014	[636,496]	[467,442,407]	-7	hSpCas9	negative selection	5313037
40930006	40930028	15	+	27760321	HT29	viability after 10 days	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.02155356887088411	[751,586]	[584,818,1133]	0	hSpCas9	negative selection	5313038
40930052	40930074	15	+	27760321	HT29	viability after 10 days	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	0.030040599427165846	[374,292]	[321,283,661]	0	hSpCas9	negative selection	5313039
40930633	40930655	15	+	27760321	HT29	viability after 10 days	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.012880304169680501	[519,405]	[549,442,748]	0	hSpCas9	negative selection	5313040
40930657	40930679	15	+	27760321	HT29	viability after 10 days	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	0.21775383499043466	[410,320]	[484,426,675]	3	hSpCas9	negative selection	5313041
40929892	40929914	15	+	27760321	MOLM13	viability	ATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.7710427927981025	[733,636]	[278,180]	-5	hSpCas9	negative selection	5396500
40930006	40930028	15	+	27760321	MOLM13	viability	TTCGGGACCGTCTCCACGCCGG	DLL4	ENSG00000128917	0.17894880739326768	[968,751]	[683,427]	1	hSpCas9	negative selection	5396501
40930052	40930074	15	+	27760321	MOLM13	viability	TCCGGGACGACAGTAGCGGCGG	DLL4	ENSG00000128917	-0.722897257861816	[491,374]	[112,175]	-4	hSpCas9	negative selection	5396502
40930633	40930655	15	+	27760321	MOLM13	viability	CTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	-0.20309959632206173	[663,519]	[224,341]	-1	hSpCas9	negative selection	5396503
40930657	40930679	15	+	27760321	MOLM13	viability	CGCGCCAGGAGACGACCTGCGG	DLL4	ENSG00000128917	-0.9213151866272139	[533,410]	[203,84]	-5	hSpCas9	negative selection	5396504
40929352	40929375	15	+	27661255	K562	viability	GCGCGCAGGCCGGGAACACGAGG	DLL4	ENSG00000128917	0.1257964571113246	[477,454]	[508,319]	4	dCas9-KRAB	negative selection	5475235
40929414	40929437	15	-	27661255	K562	viability	GGCTGCAAGCGGGCTAGTGCCGG	DLL4	ENSG00000128917	0.0492978260016827	[586,577]	[513,453]	1	dCas9-KRAB	negative selection	5475236
40929660	40929683	15	-	27661255	K562	viability	GACGCTGCCGCCATCCCCTCGGG	DLL4	ENSG00000128917	0.03171778889150448	[720,606]	[565,524]	1	dCas9-KRAB	negative selection	5475237
40929819	40929842	15	-	27661255	K562	viability	GCACAGGGACCGAGGGAAGGAGG	DLL4	ENSG00000128917	-0.44763051376120383	[804,834]	[547,421]	-7	dCas9-KRAB	negative selection	5475238
40929891	40929914	15	+	27260156	BXPC3	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.331331753343153	[138]	[286,100,176,154]	7	hSpCas9	negative selection	5539515
40929975	40929998	15	-	27260156	BXPC3	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.3389553052287551	[335]	[453,408,498,409]	7	hSpCas9	negative selection	5539516
40930632	40930655	15	+	27260156	BXPC3	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.1367690894844038	[1018]	[1213,1231,1012,1211]	3	hSpCas9	negative selection	5539517
40930629	40930652	15	-	27260156	BXPC3	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.3782110381818433	[197]	[125,145,212,155]	-7	hSpCas9	negative selection	5603784
40932218	40932241	15	-	27260156	BXPC3	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.1462909553686199	[831]	[654,671,832,1030]	-3	hSpCas9	negative selection	5603785
40932163	40932186	15	+	27260156	BXPC3	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5447463031508086	[637]	[878,873,1050,1116]	9	hSpCas9	negative selection	5603786
40929891	40929914	15	+	27260156	A673	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.12221622901830709	[138]	[134,178,159,250]	3	hSpCas9	negative selection	5660766
40929975	40929998	15	-	27260156	A673	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.22729360569076978	[335]	[555,471,449,416]	5	hSpCas9	negative selection	5660767
40930632	40930655	15	+	27260156	A673	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.35543080145374395	[1018]	[1677,1412,1498,1692]	7	hSpCas9	negative selection	5660768
40930629	40930652	15	-	27260156	A673	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.4565144147435938	[197]	[206,121,161,208]	-8	hSpCas9	negative selection	5725035
40932218	40932241	15	-	27260156	A673	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.14799242482000663	[831]	[1111,859,732,927]	-4	hSpCas9	negative selection	5725036
40932163	40932186	15	+	27260156	A673	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5843240783372022	[637]	[1331,1044,1082,1156]	9	hSpCas9	negative selection	5725037
40929891	40929914	15	+	27260156	A375	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.3547217073059181	[138]	[193,143,107,70]	-5	hSpCas9	negative selection	5782017
40929975	40929998	15	-	27260156	A375	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.5903141989018553	[335]	[880,669,451,394]	8	hSpCas9	negative selection	5782018
40930632	40930655	15	+	27260156	A375	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.2272428060477496	[1018]	[1213,1616,1416,1353]	3	hSpCas9	negative selection	5782019
40930629	40930652	15	-	27260156	A375	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.4676964660219989	[197]	[165,309,163,60]	-6	hSpCas9	negative selection	5846286
40932218	40932241	15	-	27260156	A375	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.09439479650464355	[831]	[1050,1328,1050,785]	1	hSpCas9	negative selection	5846287
40932163	40932186	15	+	27260156	A375	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.7110087052112987	[637]	[1385,1129,1032,1303]	9	hSpCas9	negative selection	5846288
40929891	40929914	15	+	27260156	COLO741	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.6293821158221504	[138]	[234,403,187]	9	hSpCas9	negative selection	5903268
40929975	40929998	15	-	27260156	COLO741	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.41299149433344035	[335]	[673,587,467]	8	hSpCas9	negative selection	5903269
40930632	40930655	15	+	27260156	COLO741	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3803495372801673	[1018]	[1630,2067,1398]	7	hSpCas9	negative selection	5903270
40930629	40930652	15	-	27260156	COLO741	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	0.15576532317096192	[197]	[279,286,277]	3	hSpCas9	negative selection	5967537
40932218	40932241	15	-	27260156	COLO741	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.25405852057597145	[831]	[1046,856,788]	-5	hSpCas9	negative selection	5967538
40932163	40932186	15	+	27260156	COLO741	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.736418504030561	[637]	[1377,1490,1214]	9	hSpCas9	negative selection	5967539
40929891	40929914	15	+	27260156	CAL120	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.2045448788164974	[138]	[138,70,236]	-3	hSpCas9	negative selection	6024519
40929975	40929998	15	-	27260156	CAL120	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.6412309273712472	[335]	[531,585,816]	8	hSpCas9	negative selection	6024520
40930632	40930655	15	+	27260156	CAL120	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.5272685835726163	[1018]	[2415,1648,1510]	7	hSpCas9	negative selection	6024521
40930629	40930652	15	-	27260156	CAL120	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.5858233816630594	[197]	[186,152,155]	-7	hSpCas9	negative selection	6088788
40932218	40932241	15	-	27260156	CAL120	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.2629079172867055	[831]	[1135,1479,1096]	4	hSpCas9	negative selection	6088789
40932163	40932186	15	+	27260156	CAL120	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.6951870474797935	[637]	[1222,1149,1469]	8	hSpCas9	negative selection	6088790
40929891	40929914	15	+	27260156	CADOES1	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.06946863404075687	[138]	[166,74,65,186]	-1	hSpCas9	negative selection	6145770
40929975	40929998	15	-	27260156	CADOES1	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.35833548788418335	[335]	[301,475,368,457]	6	hSpCas9	negative selection	6145771
40930632	40930655	15	+	27260156	CADOES1	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.26084566611995386	[1018]	[1173,1011,1164,1192]	4	hSpCas9	negative selection	6145772
40930629	40930652	15	-	27260156	CADOES1	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.6977637442848432	[197]	[142,124,74,110]	-8	hSpCas9	negative selection	6210039
40932218	40932241	15	-	27260156	CADOES1	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.02869139393166431	[831]	[761,719,721,832]	0	hSpCas9	negative selection	6210040
40932163	40932186	15	+	27260156	CADOES1	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.7790603181033188	[637]	[1184,1004,801,1082]	9	hSpCas9	negative selection	6210041
40929891	40929914	15	+	27260156	EWS502	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.2911380684416607	[138]	[205,153,157,200]	5	hSpCas9	negative selection	6267021
40929975	40929998	15	-	27260156	EWS502	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.2726385379442081	[335]	[432,413,399,473]	5	hSpCas9	negative selection	6267022
40930632	40930655	15	+	27260156	EWS502	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.4089309447831484	[1018]	[1188,1707,1631,1201]	7	hSpCas9	negative selection	6267023
40930629	40930652	15	-	27260156	EWS502	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.0012509484414899852	[197]	[278,153,137,262]	0	hSpCas9	negative selection	6331290
40932218	40932241	15	-	27260156	EWS502	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.040834671132068734	[831]	[780,1048,798,789]	0	hSpCas9	negative selection	6331291
40932163	40932186	15	+	27260156	EWS502	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.8483309568070517	[637]	[1044,1003,1086,1794]	9	hSpCas9	negative selection	6331292
40929891	40929914	15	+	27260156	EW8	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.093615907279754	[138]	[65,94,90,226]	1	hSpCas9	negative selection	6388272
40929975	40929998	15	-	27260156	EW8	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	-0.1643123278831447	[335]	[311,346,181,148]	-3	hSpCas9	negative selection	6388273
40930632	40930655	15	+	27260156	EW8	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.2815461574052456	[1018]	[1307,856,855,1048]	5	hSpCas9	negative selection	6388274
40930629	40930652	15	-	27260156	EW8	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.549488823387132	[197]	[169,89,126,54]	-7	hSpCas9	negative selection	6452541
40932218	40932241	15	-	27260156	EW8	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.051782521652663616	[831]	[850,624,585,766]	0	hSpCas9	negative selection	6452542
40932163	40932186	15	+	27260156	EW8	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.6496658519130275	[637]	[933,755,844,714]	9	hSpCas9	negative selection	6452543
40929891	40929914	15	+	27260156	CORL105	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.1510842709450706	[138]	[89,168,148,175]	-3	hSpCas9	negative selection	6509523
40929975	40929998	15	-	27260156	CORL105	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.15238022798451994	[335]	[556,409,414,367]	3	hSpCas9	negative selection	6509524
40930632	40930655	15	+	27260156	CORL105	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.37810457311567314	[1018]	[1650,1355,1707,1517]	7	hSpCas9	negative selection	6509525
40930629	40930652	15	-	27260156	CORL105	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.18703242196888215	[197]	[177,198,256,187]	-3	hSpCas9	negative selection	6573792
40932218	40932241	15	-	27260156	CORL105	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.08733949027039467	[831]	[825,847,982,1017]	-2	hSpCas9	negative selection	6573793
40932163	40932186	15	+	27260156	CORL105	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.3950361262467793	[637]	[946,913,1169,926]	7	hSpCas9	negative selection	6573794
40929891	40929914	15	+	27260156	HS294T	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.7840933100437049	[138]	[122,96,77,63]	8	hSpCas9	negative selection	6630774
40929975	40929998	15	-	27260156	HS294T	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.14502110143307095	[335]	[132,125,136,186]	2	hSpCas9	negative selection	6630775
40930632	40930655	15	+	27260156	HS294T	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.29473411626947854	[1018]	[357,504,486,614]	4	hSpCas9	negative selection	6630776
40930629	40930652	15	-	27260156	HS294T	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.48207301340486897	[197]	[82,54,39,34]	-6	hSpCas9	negative selection	6695043
40932218	40932241	15	-	27260156	HS294T	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.11963913964717898	[831]	[312,392,337,355]	1	hSpCas9	negative selection	6695044
40932163	40932186	15	+	27260156	HS294T	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.46499257765443125	[637]	[251,385,313,430]	6	hSpCas9	negative selection	6695045
40929891	40929914	15	+	27260156	HCC44	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.5527270870543639	[138]	[191,154,491,136]	8	hSpCas9	negative selection	6752025
40929975	40929998	15	-	27260156	HCC44	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.2591712931710718	[335]	[468,582,370,363]	4	hSpCas9	negative selection	6752026
40930632	40930655	15	+	27260156	HCC44	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.1750890785638386	[1018]	[1395,1389,1253,1146]	2	hSpCas9	negative selection	6752027
40930629	40930652	15	-	27260156	HCC44	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.6575890940150959	[197]	[159,195,115,85]	-7	hSpCas9	negative selection	6816294
40932218	40932241	15	-	27260156	HCC44	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.07861729898754233	[831]	[666,1027,912,911]	-1	hSpCas9	negative selection	6816295
40932163	40932186	15	+	27260156	HCC44	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.6418226306327334	[637]	[1264,791,1438,1112]	9	hSpCas9	negative selection	6816296
40929891	40929914	15	+	27260156	G402	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.23314409880992804	[138]	[243,241,213,109]	3	hSpCas9	negative selection	6873276
40929975	40929998	15	-	27260156	G402	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	-0.11824096935117939	[335]	[291,346,599,261]	-1	hSpCas9	negative selection	6873277
40930632	40930655	15	+	27260156	G402	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.13615176560855002	[1018]	[1301,1683,1400,1095]	1	hSpCas9	negative selection	6873278
40930629	40930652	15	-	27260156	G402	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.46948208339089414	[197]	[400,76,64,180]	-5	hSpCas9	negative selection	6937545
40932218	40932241	15	-	27260156	G402	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.29727274323441044	[831]	[914,1119,1694,1201]	4	hSpCas9	negative selection	6937546
40932163	40932186	15	+	27260156	G402	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.7058467686929827	[637]	[1256,1520,1102,1208]	8	hSpCas9	negative selection	6937547
40929891	40929914	15	+	27260156	L33	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.5755487364556564	[138]	[285,53,122,212]	9	hSpCas9	negative selection	6994527
40929975	40929998	15	-	27260156	L33	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.45701930898357807	[335]	[471,175,325,424]	8	hSpCas9	negative selection	6994528
40930632	40930655	15	+	27260156	L33	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3474503349881064	[1018]	[1256,574,973,980]	7	hSpCas9	negative selection	6994529
40930629	40930652	15	-	27260156	L33	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.40463001412304456	[197]	[99,79,110,127]	-7	hSpCas9	negative selection	7058796
40932218	40932241	15	-	27260156	L33	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.14974621246388264	[831]	[857,421,516,981]	3	hSpCas9	negative selection	7058797
40932163	40932186	15	+	27260156	L33	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.4013925598958542	[637]	[791,300,521,1012]	8	hSpCas9	negative selection	7058798
40929891	40929914	15	+	27260156	K562	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.36220921953914487	[138]	[117,48,168,51]	-4	hSpCas9	negative selection	7115778
40929975	40929998	15	-	27260156	K562	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.39224378187086173	[335]	[514,213,250,563]	5	hSpCas9	negative selection	7115779
40930632	40930655	15	+	27260156	K562	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.20363175408114031	[1018]	[745,1147,1381,884]	2	hSpCas9	negative selection	7115780
40930629	40930652	15	-	27260156	K562	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-1.521190755476802	[197]	[71,33,113,27]	-9	hSpCas9	negative selection	7180047
40932218	40932241	15	-	27260156	K562	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.13954141698975198	[831]	[1225,749,346,941]	1	hSpCas9	negative selection	7180048
40932163	40932186	15	+	27260156	K562	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.9775002917800989	[637]	[984,1002,1626,853]	9	hSpCas9	negative selection	7180049
40929891	40929914	15	+	27260156	HT29	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.022273552474991742	[138]	[135,178,213,155]	0	hSpCas9	negative selection	7237029
40929975	40929998	15	-	27260156	HT29	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.1774228457466755	[335]	[515,286,627,408]	3	hSpCas9	negative selection	7237030
40930632	40930655	15	+	27260156	HT29	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3106916022279609	[1018]	[1725,1680,1448,1330]	6	hSpCas9	negative selection	7237031
40930629	40930652	15	-	27260156	HT29	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.6325911743200081	[197]	[162,236,67,158]	-8	hSpCas9	negative selection	7301298
40932218	40932241	15	-	27260156	HT29	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.3222491641581081	[831]	[1052,917,702,608]	-6	hSpCas9	negative selection	7301299
40932163	40932186	15	+	27260156	HT29	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5200295341716041	[637]	[1560,1121,915,902]	8	hSpCas9	negative selection	7301300
40929891	40929914	15	+	27260156	MHHES1	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.7248412405061075	[138]	[319,236,127,330]	9	hSpCas9	negative selection	7358280
40929975	40929998	15	-	27260156	MHHES1	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.3173778585781527	[335]	[489,511,467,422]	6	hSpCas9	negative selection	7358281
40930632	40930655	15	+	27260156	MHHES1	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.31217160223963747	[1018]	[1856,1419,1193,1279]	5	hSpCas9	negative selection	7358282
40930629	40930652	15	-	27260156	MHHES1	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-1.1455336176534214	[197]	[78,101,164,61]	-9	hSpCas9	negative selection	7422549
40932218	40932241	15	-	27260156	MHHES1	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.03644470221313789	[831]	[1138,951,899,871]	0	hSpCas9	negative selection	7422550
40932163	40932186	15	+	27260156	MHHES1	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.7416685846448182	[637]	[1630,1245,1094,926]	9	hSpCas9	negative selection	7422551
40929891	40929914	15	+	27260156	MEWO	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.05086646674464235	[138]	[132,131,112]	-1	hSpCas9	negative selection	7479531
40929975	40929998	15	-	27260156	MEWO	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.09340040567548324	[335]	[442,313,269]	2	hSpCas9	negative selection	7479532
40930632	40930655	15	+	27260156	MEWO	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.35642991571657934	[1018]	[1686,942,1122]	7	hSpCas9	negative selection	7479533
40930629	40930652	15	-	27260156	MEWO	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.013916001681030687	[197]	[166,215,163]	0	hSpCas9	negative selection	7543800
40932218	40932241	15	-	27260156	MEWO	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.2760175536932429	[831]	[696,618,622]	-6	hSpCas9	negative selection	7543801
40932163	40932186	15	+	27260156	MEWO	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.3769160310802774	[637]	[868,838,634]	7	hSpCas9	negative selection	7543802
40929891	40929914	15	+	27260156	LNCAPCLONEFGC	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.19299470337263358	[138]	[249,69,133,122]	3	hSpCas9	negative selection	7600782
40929975	40929998	15	-	27260156	LNCAPCLONEFGC	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.48173690432934035	[335]	[399,392,556,371]	7	hSpCas9	negative selection	7600783
40930632	40930655	15	+	27260156	LNCAPCLONEFGC	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.5871266028707687	[1018]	[1415,1381,1571,1202]	8	hSpCas9	negative selection	7600784
40930629	40930652	15	-	27260156	LNCAPCLONEFGC	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.4050565167349336	[197]	[227,74,135,104]	-6	hSpCas9	negative selection	7665051
40932218	40932241	15	-	27260156	LNCAPCLONEFGC	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.08745051116365354	[831]	[798,659,868,893]	1	hSpCas9	negative selection	7665052
40932163	40932186	15	+	27260156	LNCAPCLONEFGC	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5653914868972881	[637]	[926,778,1050,695]	8	hSpCas9	negative selection	7665053
40929891	40929914	15	+	27260156	PANC0327	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.7704366235833489	[138]	[81,82,91,31]	-8	hSpCas9	negative selection	7722033
40929975	40929998	15	-	27260156	PANC0327	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	-0.1922971057819735	[335]	[356,305,265,117]	-3	hSpCas9	negative selection	7722034
40930632	40930655	15	+	27260156	PANC0327	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.7217371747211001	[1018]	[2233,1064,1537,1249]	9	hSpCas9	negative selection	7722035
40930629	40930652	15	-	27260156	PANC0327	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	0.15992280359622346	[197]	[87,168,398,124]	2	hSpCas9	negative selection	7786302
40932218	40932241	15	-	27260156	PANC0327	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.049356424969035584	[831]	[968,677,569,664]	0	hSpCas9	negative selection	7786303
40932163	40932186	15	+	27260156	PANC0327	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.29422313121534605	[637]	[750,564,735,748]	4	hSpCas9	negative selection	7786304
40929891	40929914	15	+	27260156	NCIH2009	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.013952608030823654	[138]	[277,170,144]	0	hSpCas9	negative selection	7843284
40929975	40929998	15	-	27260156	NCIH2009	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.7358116789951794	[335]	[888,517,962]	8	hSpCas9	negative selection	7843285
40930632	40930655	15	+	27260156	NCIH2009	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3105741314585113	[1018]	[1918,1508,1900]	4	hSpCas9	negative selection	7843286
40930629	40930652	15	-	27260156	NCIH2009	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.8272106745830767	[197]	[323,139,36]	-7	hSpCas9	negative selection	7907553
40932218	40932241	15	-	27260156	NCIH2009	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.07248579667668875	[831]	[1437,976,1296]	1	hSpCas9	negative selection	7907554
40932163	40932186	15	+	27260156	NCIH2009	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.3681394795190591	[637]	[1505,919,1097]	5	hSpCas9	negative selection	7907555
40929891	40929914	15	+	27260156	NCIH1373	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.2560311181745456	[138]	[144,103,108,44]	-3	hSpCas9	negative selection	7964535
40929975	40929998	15	-	27260156	NCIH1373	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.6588899442230138	[335]	[873,566,723,60]	6	hSpCas9	negative selection	7964536
40930632	40930655	15	+	27260156	NCIH1373	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.16256923998266992	[1018]	[1255,915,1525,380]	1	hSpCas9	negative selection	7964537
40930629	40930652	15	-	27260156	NCIH1373	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-1.277434504192905	[197]	[53,25,91,52]	-8	hSpCas9	negative selection	8028804
40932218	40932241	15	-	27260156	NCIH1373	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.3585643603909485	[831]	[1628,982,642,433]	3	hSpCas9	negative selection	8028805
40932163	40932186	15	+	27260156	NCIH1373	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	1.11210697600599	[637]	[1771,1535,1053,493]	9	hSpCas9	negative selection	8028806
40929891	40929914	15	+	27260156	PATU8902	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.6361872949476692	[138]	[48,172,133,141]	-6	hSpCas9	negative selection	8085786
40929975	40929998	15	-	27260156	PATU8902	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.6279233409019147	[335]	[973,499,371,1182]	6	hSpCas9	negative selection	8085787
40930632	40930655	15	+	27260156	PATU8902	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.4412941058417461	[1018]	[2334,1711,1998,1579]	4	hSpCas9	negative selection	8085788
40930629	40930652	15	-	27260156	PATU8902	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-1.1974258753993976	[197]	[166,203,56,60]	-8	hSpCas9	negative selection	8150055
40932218	40932241	15	-	27260156	PATU8902	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.05753679781928278	[831]	[1096,1252,993,1569]	0	hSpCas9	negative selection	8150056
40932163	40932186	15	+	27260156	PATU8902	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.7319861382226264	[637]	[1018,1889,1377,1658]	7	hSpCas9	negative selection	8150057
40929891	40929914	15	+	27260156	PANC1	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.15299322605828625	[138]	[93,137,225,81]	2	hSpCas9	negative selection	8207037
40929975	40929998	15	-	27260156	PANC1	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.5104329912872739	[335]	[523,556,362,247]	7	hSpCas9	negative selection	8207038
40930632	40930655	15	+	27260156	PANC1	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.47816786526473276	[1018]	[1043,1893,1178,929]	7	hSpCas9	negative selection	8207039
40930629	40930652	15	-	27260156	PANC1	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.035319048726099256	[197]	[108,201,120,226]	0	hSpCas9	negative selection	8271306
40932218	40932241	15	-	27260156	PANC1	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.12566200646427972	[831]	[643,1059,596,428]	-2	hSpCas9	negative selection	8271307
40932163	40932186	15	+	27260156	PANC1	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5488034306092899	[637]	[741,1284,641,648]	8	hSpCas9	negative selection	8271308
40929891	40929914	15	+	27260156	PANC0813	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.6199029408436227	[138]	[270,191,216,320]	8	hSpCas9	negative selection	8328288
40929975	40929998	15	-	27260156	PANC0813	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.7188433575085248	[335]	[724,717,621,544]	9	hSpCas9	negative selection	8328289
40930632	40930655	15	+	27260156	PANC0813	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.49414403968877174	[1018]	[1939,2060,1535,1250]	7	hSpCas9	negative selection	8328290
40930629	40930652	15	-	27260156	PANC0813	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.6538494568181934	[197]	[167,152,178,95]	-7	hSpCas9	negative selection	8392557
40932218	40932241	15	-	27260156	PANC0813	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.015333181362975457	[831]	[1076,881,1011,908]	0	hSpCas9	negative selection	8392558
40932163	40932186	15	+	27260156	PANC0813	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.46274420507993774	[637]	[972,1160,1203,799]	7	hSpCas9	negative selection	8392559
40929891	40929914	15	+	27260156	RDES	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.3637031450097017	[138]	[113,181,299,254]	6	hSpCas9	negative selection	8449539
40929975	40929998	15	-	27260156	RDES	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.4225538571204744	[335]	[487,445,501,651]	6	hSpCas9	negative selection	8449540
40930632	40930655	15	+	27260156	RDES	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.23910460399890066	[1018]	[1162,1332,1487,1593]	4	hSpCas9	negative selection	8449541
40930629	40930652	15	-	27260156	RDES	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.8918969716268708	[197]	[93,121,153,124]	-9	hSpCas9	negative selection	8513808
40932218	40932241	15	-	27260156	RDES	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.056366807083510495	[831]	[708,849,1070,1110]	-1	hSpCas9	negative selection	8513809
40932163	40932186	15	+	27260156	RDES	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.6438247692288842	[637]	[903,1105,1304,1325]	9	hSpCas9	negative selection	8513810
40929891	40929914	15	+	27260156	PC3	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	-0.09442852426126436	[138]	[148,74,150,124]	-2	hSpCas9	negative selection	8570790
40929975	40929998	15	-	27260156	PC3	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.3204983764296357	[335]	[193,436,842,430]	7	hSpCas9	negative selection	8570791
40930632	40930655	15	+	27260156	PC3	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3648498698332592	[1018]	[877,1191,2044,1470]	7	hSpCas9	negative selection	8570792
40930629	40930652	15	-	27260156	PC3	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.17546610731426493	[197]	[119,119,360,179]	-4	hSpCas9	negative selection	8635059
40932218	40932241	15	-	27260156	PC3	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.12346433344547036	[831]	[397,849,1258,824]	-3	hSpCas9	negative selection	8635060
40932163	40932186	15	+	27260156	PC3	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.4147709462056638	[637]	[556,769,1273,1008]	8	hSpCas9	negative selection	8635061
40929891	40929914	15	+	27260156	PATU8988T	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.28761862117374437	[138]	[62,87,314,181]	5	hSpCas9	negative selection	8692041
40929975	40929998	15	-	27260156	PATU8988T	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.4915452371460097	[335]	[531,651,300,352]	7	hSpCas9	negative selection	8692042
40930632	40930655	15	+	27260156	PATU8988T	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.11922801813895068	[1018]	[1111,1145,1031,988]	2	hSpCas9	negative selection	8692043
40930629	40930652	15	-	27260156	PATU8988T	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.10742805943794842	[197]	[210,175,83,245]	-2	hSpCas9	negative selection	8756310
40932218	40932241	15	-	27260156	PATU8988T	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.1442370715222211	[831]	[916,940,859,836]	2	hSpCas9	negative selection	8756311
40932163	40932186	15	+	27260156	PATU8988T	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.6012237666666763	[637]	[849,1076,829,1003]	8	hSpCas9	negative selection	8756312
40929891	40929914	15	+	27260156	T47D	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.12326581561683381	[138]	[171,180,216,132]	2	hSpCas9	negative selection	8813292
40929975	40929998	15	-	27260156	T47D	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.04054495327819008	[335]	[434,406,356,411]	0	hSpCas9	negative selection	8813293
40930632	40930655	15	+	27260156	T47D	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.2702376327476743	[1018]	[1447,1260,1425,1611]	6	hSpCas9	negative selection	8813294
40930629	40930652	15	-	27260156	T47D	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.3030439045646305	[197]	[227,125,229,167]	-6	hSpCas9	negative selection	8877561
40932218	40932241	15	-	27260156	T47D	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.16804873386836428	[831]	[856,710,827,1074]	-4	hSpCas9	negative selection	8877562
40932163	40932186	15	+	27260156	T47D	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5801397492252184	[637]	[1148,932,1133,1247]	9	hSpCas9	negative selection	8877563
40929891	40929914	15	+	27260156	SU8686	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.2873352823410029	[138]	[105,123,119,364]	5	hSpCas9	negative selection	8934543
40929975	40929998	15	-	27260156	SU8686	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.34118783787248175	[335]	[357,409,381,565]	6	hSpCas9	negative selection	8934544
40930632	40930655	15	+	27260156	SU8686	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.23712773142722754	[1018]	[1018,1297,1075,1396]	4	hSpCas9	negative selection	8934545
40930629	40930652	15	-	27260156	SU8686	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.04127793361184384	[197]	[188,119,275,187]	0	hSpCas9	negative selection	8998812
40932218	40932241	15	-	27260156	SU8686	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.021195120078742025	[831]	[792,707,939,942]	0	hSpCas9	negative selection	8998813
40932163	40932186	15	+	27260156	SU8686	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5757366418434652	[637]	[874,816,1041,1078]	8	hSpCas9	negative selection	8998814
40929891	40929914	15	+	27260156	SKES1	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.1732862197478211	[138]	[315,109,83,133]	4	hSpCas9	negative selection	9055794
40929975	40929998	15	-	27260156	SKES1	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.3680490333504452	[335]	[463,379,451,427]	7	hSpCas9	negative selection	9055795
40930632	40930655	15	+	27260156	SKES1	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3878868225838552	[1018]	[1819,1340,1095,1143]	7	hSpCas9	negative selection	9055796
40930629	40930652	15	-	27260156	SKES1	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.4684815046845372	[197]	[200,117,123,132]	-8	hSpCas9	negative selection	9120063
40932218	40932241	15	-	27260156	SKES1	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.07791471011512352	[831]	[686,751,917,762]	-2	hSpCas9	negative selection	9120064
40932163	40932186	15	+	27260156	SKES1	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.49759790811380056	[637]	[1197,848,987,617]	8	hSpCas9	negative selection	9120065
40929891	40929914	15	+	27260156	TOV112D	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.27848298726740484	[138]	[87,302,164,145]	5	hSpCas9	negative selection	9177045
40929975	40929998	15	-	27260156	TOV112D	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.4238613954305311	[335]	[458,415,435,484]	7	hSpCas9	negative selection	9177046
40930632	40930655	15	+	27260156	TOV112D	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.3989463711136705	[1018]	[1330,1268,1400,1358]	7	hSpCas9	negative selection	9177047
40930629	40930652	15	-	27260156	TOV112D	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-1.0552148316339	[197]	[89,113,97,83]	-9	hSpCas9	negative selection	9241314
40932218	40932241	15	-	27260156	TOV112D	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.36130128963073366	[831]	[491,823,817,493]	-6	hSpCas9	negative selection	9241315
40932163	40932186	15	+	27260156	TOV112D	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.4948549339734868	[637]	[891,685,1074,893]	8	hSpCas9	negative selection	9241316
40929891	40929914	15	+	27260156	TC71	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.20048772243167678	[138]	[176,125,183,198]	5	hSpCas9	negative selection	9298296
40929975	40929998	15	-	27260156	TC71	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.07753245928022562	[335]	[360,359,411,386]	2	hSpCas9	negative selection	9298297
40930632	40930655	15	+	27260156	TC71	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.10721520094247894	[1018]	[1106,1234,1231,1128]	2	hSpCas9	negative selection	9298298
40930629	40930652	15	-	27260156	TC71	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.141064738988107	[197]	[221,216,148,181]	-4	hSpCas9	negative selection	9362565
40932218	40932241	15	-	27260156	TC71	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	-0.07754509299473789	[831]	[617,907,783,1092]	-2	hSpCas9	negative selection	9362566
40932163	40932186	15	+	27260156	TC71	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.5950975031807931	[637]	[1067,1128,881,1058]	9	hSpCas9	negative selection	9362567
40929891	40929914	15	+	27260156	TC32	viability	CATCAACGAGCGCGGCGTACTGG	DLL4	ENSG00000128917	0.36214859855061454	[138]	[136,163,151,212]	6	hSpCas9	negative selection	9419547
40929975	40929998	15	-	27260156	TC32	viability	GTCCGGGCGAGACGACCGCCTGG	DLL4	ENSG00000128917	0.4895111473354994	[335]	[431,359,509,490]	8	hSpCas9	negative selection	9419548
40930632	40930655	15	+	27260156	TC32	viability	TCTCGCTCATCATCGAAGCTTGG	DLL4	ENSG00000128917	0.43138159222555905	[1018]	[1004,986,1844,1513]	7	hSpCas9	negative selection	9419549
40930629	40930652	15	-	27260156	TC32	viability	AGCTTCGATGATGAGCGAGAAGG	DLL4	ENSG00000128917	-0.5071464456189458	[197]	[72,93,270,123]	-7	hSpCas9	negative selection	9483816
40932218	40932241	15	-	27260156	TC32	viability	CCTACTCACAGGCACTCTGCTGG	DLL4	ENSG00000128917	0.004519267255397419	[831]	[706,643,903,925]	0	hSpCas9	negative selection	9483817
40932163	40932186	15	+	27260156	TC32	viability	TCCCTTAGCTATCTGTCTTTCGG	DLL4	ENSG00000128917	0.6291907013505592	[637]	[958,656,946,1207]	9	hSpCas9	negative selection	9483818
40929691	40929714	15	-	27869803	HPAFII	viability after 27 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.5960236582905643	[409]	[369,288,NaN]	5	hSpCas9	negative selection	9553497
40929854	40929877	15	-	27869803	HPAFII	viability after 27 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.06898228248464455	[342]	[268,90,NaN]	0	hSpCas9	negative selection	9553498
40930672	40930695	15	-	27869803	HPAFII	viability after 27 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.20992306937423122	[141]	[81,49,NaN]	-1	hSpCas9	negative selection	9553499
40931506	40931529	15	-	27869803	HPAFII	viability after 27 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-1.0687470064135371	[106]	[34,19,NaN]	-6	hSpCas9	negative selection	9553500
40932182	40932205	15	+	27869803	HPAFII	viability after 27 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.5086366779159421	[649]	[399,557,NaN]	4	hSpCas9	negative selection	9553501
40932338	40932361	15	-	27869803	HPAFII	viability after 27 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.50494001016	[238]	[93,83,NaN]	-4	hSpCas9	negative selection	9553502
40929691	40929714	15	-	27869803	HPAFII	viability after 15 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.09428983825646076	[409]	[532,337,NaN]	-1	hSpCas9	negative selection	9635946
40929854	40929877	15	-	27869803	HPAFII	viability after 15 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.802055568380502	[342]	[269,174,NaN]	-7	hSpCas9	negative selection	9635947
40930672	40930695	15	-	27869803	HPAFII	viability after 15 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	0.052477189088669385	[141]	[140,168,NaN]	0	hSpCas9	negative selection	9635948
40931506	40931529	15	-	27869803	HPAFII	viability after 15 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-0.038609884300558894	[106]	[209,50,NaN]	0	hSpCas9	negative selection	9635949
40932182	40932205	15	+	27869803	HPAFII	viability after 15 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	-0.061166245341937264	[649]	[766,608,NaN]	0	hSpCas9	negative selection	9635950
40932338	40932361	15	-	27869803	HPAFII	viability after 15 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.06116249774864413	[238]	[275,262,NaN]	0	hSpCas9	negative selection	9635951
40929691	40929714	15	-	27869803	ASPC1	viability after 36 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.1918160319579556	[1032]	[871,243,217]	2	hSpCas9	negative selection	9718395
40929854	40929877	15	-	27869803	ASPC1	viability after 36 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.0866183433292954	[691]	[196,314,176]	-1	hSpCas9	negative selection	9718396
40930672	40930695	15	-	27869803	ASPC1	viability after 36 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-2.2768566286913217	[357]	[27,26,22]	-9	hSpCas9	negative selection	9718397
40931506	40931529	15	-	27869803	ASPC1	viability after 36 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-0.14116242764194498	[241]	[38,164,31]	-1	hSpCas9	negative selection	9718398
40932182	40932205	15	+	27869803	ASPC1	viability after 36 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.24127161638411798	[1272]	[466,651,459]	2	hSpCas9	negative selection	9718399
40932338	40932361	15	-	27869803	ASPC1	viability after 36 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.7941323184607154	[457]	[677,221,36]	7	hSpCas9	negative selection	9718400
40929691	40929714	15	-	27869803	PATU8988S	viability after 35 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.6550669154939529	[1249]	[409,228,NaN]	-6	hSpCas9	negative selection	9800844
40929854	40929877	15	-	27869803	PATU8988S	viability after 35 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.6925735911153161	[645]	[153,167,NaN]	-6	hSpCas9	negative selection	9800845
40930672	40930695	15	-	27869803	PATU8988S	viability after 35 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.7934487476550817	[352]	[93,69,NaN]	-7	hSpCas9	negative selection	9800846
40931506	40931529	15	-	27869803	PATU8988S	viability after 35 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-0.21931901909015927	[187]	[81,47,NaN]	-2	hSpCas9	negative selection	9800847
40932182	40932205	15	+	27869803	PATU8988S	viability after 35 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	-0.051794308254224486	[1077]	[354,482,NaN]	0	hSpCas9	negative selection	9800848
40932338	40932361	15	-	27869803	PATU8988S	viability after 35 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.5458415657833046	[492]	[139,131,NaN]	-5	hSpCas9	negative selection	9800849
40929691	40929714	15	-	27869803	PATU8988S	viability after 31 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.7726647522297871	[1249]	[234,363,NaN]	-7	hSpCas9	negative selection	9883293
40929854	40929877	15	-	27869803	PATU8988S	viability after 31 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-1.088654712189618	[645]	[110,133,NaN]	-8	hSpCas9	negative selection	9883294
40930672	40930695	15	-	27869803	PATU8988S	viability after 31 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.2977248284663039	[352]	[66,174,NaN]	-3	hSpCas9	negative selection	9883295
40931506	40931529	15	-	27869803	PATU8988S	viability after 31 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-0.8086439179971576	[187]	[33,53,NaN]	-7	hSpCas9	negative selection	9883296
40932182	40932205	15	+	27869803	PATU8988S	viability after 31 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	-0.05312883764420351	[1077]	[335,513,NaN]	0	hSpCas9	negative selection	9883297
40932338	40932361	15	-	27869803	PATU8988S	viability after 31 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	0.2902973892549107	[492]	[224,259,NaN]	3	hSpCas9	negative selection	9883298
40929691	40929714	15	-	27869803	HPAFII	viability after 35 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.7349770447860584	[409]	[320,372,NaN]	5	hSpCas9	negative selection	9965742
40929854	40929877	15	-	27869803	HPAFII	viability after 35 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	-0.3091055577974205	[342]	[213,56,NaN]	-2	hSpCas9	negative selection	9965743
40930672	40930695	15	-	27869803	HPAFII	viability after 35 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.36601729564479635	[141]	[83,23,NaN]	-2	hSpCas9	negative selection	9965744
40931506	40931529	15	-	27869803	HPAFII	viability after 35 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-1.2588081199736882	[106]	[0,46,NaN]	-6	hSpCas9	negative selection	9965745
40932182	40932205	15	+	27869803	HPAFII	viability after 35 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.35798619988165403	[649]	[242,622,NaN]	2	hSpCas9	negative selection	9965746
40932338	40932361	15	-	27869803	HPAFII	viability after 35 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.42268630772026816	[238]	[30,156,NaN]	-3	hSpCas9	negative selection	9965747
40929691	40929714	15	-	27869803	HPAFII	viability after 31 days	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.46492575569852	[409]	[274,363,NaN]	3	hSpCas9	negative selection	10048191
40929854	40929877	15	-	27869803	HPAFII	viability after 31 days	CAGCTGGAAGACGCCGGAGCCGG	DLL4	ENSG00000128917	0.010209673402486241	[342]	[268,111,NaN]	0	hSpCas9	negative selection	10048192
40930672	40930695	15	-	27869803	HPAFII	viability after 31 days	CGAGCTACTCACCTGGCCGCAGG	DLL4	ENSG00000128917	-0.40811198281221206	[141]	[38,82,NaN]	-3	hSpCas9	negative selection	10048193
40931506	40931529	15	-	27869803	HPAFII	viability after 31 days	GATGAGTGCATCTGGTGGCAAGG	DLL4	ENSG00000128917	-1.038435852227771	[106]	[0,59,NaN]	-6	hSpCas9	negative selection	10048194
40932182	40932205	15	+	27869803	HPAFII	viability after 31 days	TCGGGCTGTCATGAACAGAATGG	DLL4	ENSG00000128917	0.42055152564623266	[649]	[370,615,NaN]	3	hSpCas9	negative selection	10048195
40932338	40932361	15	-	27869803	HPAFII	viability after 31 days	GGATGCATTCGTTACACAGCCGG	DLL4	ENSG00000128917	-0.4496346270637106	[238]	[35,165,NaN]	-3	hSpCas9	negative selection	10048196
40930043	40930066	15	-	28162770	P31FUJ	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.8057920634694586	[179]	[120]	-6	hSpCas9	negative selection	10144673
40936568	40936591	15	-	28162770	P31FUJ	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-1.146214519418288	[193]	[102]	-7	hSpCas9	negative selection	10144674
40936529	40936552	15	+	28162770	P31FUJ	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.27108868565945976	[243]	[345]	3	hSpCas9	negative selection	10144675
40929691	40929714	15	-	28162770	P31FUJ	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.08358770693155365	[260]	[324]	0	hSpCas9	negative selection	10144676
40929954	40929977	15	-	28162770	P31FUJ	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.4600162860674455	[72]	[117]	5	hSpCas9	negative selection	10144677
40929998	40930021	15	-	28162770	P31FUJ	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.6602825916691097	[20]	[38]	7	hSpCas9	negative selection	10144678
40931596	40931619	15	-	28162770	P31FUJ	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.5426574670011661	[356]	[287]	-4	hSpCas9	negative selection	10144679
40935004	40935027	15	+	28162770	P31FUJ	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.14126351380815905	[499]	[647]	1	hSpCas9	negative selection	10144680
40936465	40936488	15	-	28162770	P31FUJ	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.6416077499817081	[76]	[57]	-5	hSpCas9	negative selection	10144681
40936546	40936569	15	-	28162770	P31FUJ	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	2.0330918555586557	[20]	[100]	9	hSpCas9	negative selection	10144682
40930043	40930066	15	-	28162770	TF1	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10314039
40936568	40936591	15	-	28162770	TF1	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	NaN	[NaN]	[90]	1	hSpCas9	negative selection	10314040
40936529	40936552	15	+	28162770	TF1	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10314041
40929691	40929714	15	-	28162770	TF1	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	NaN	[NaN]	[223]	1	hSpCas9	negative selection	10314042
40929954	40929977	15	-	28162770	TF1	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10314043
40929998	40930021	15	-	28162770	TF1	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10314044
40931596	40931619	15	-	28162770	TF1	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	NaN	[NaN]	[512]	1	hSpCas9	negative selection	10314045
40935004	40935027	15	+	28162770	TF1	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	NaN	[NaN]	[405]	1	hSpCas9	negative selection	10314046
40936465	40936488	15	-	28162770	TF1	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10314047
40936546	40936569	15	-	28162770	TF1	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10314048
40930043	40930066	15	-	28162770	SKM1	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.031924767396236925	[47]	[82]	0	hSpCas9	negative selection	10483405
40936568	40936591	15	-	28162770	SKM1	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	0.15938262381064755	[38]	[76]	1	hSpCas9	negative selection	10483406
40936529	40936552	15	+	28162770	SKM1	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.20184504393236202	[89]	[182]	2	hSpCas9	negative selection	10483407
40929691	40929714	15	-	28162770	SKM1	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.7697181688744597	[70]	[213]	7	hSpCas9	negative selection	10483408
40929954	40929977	15	-	28162770	SKM1	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.01753362978474826	[37]	[67]	0	hSpCas9	negative selection	10483409
40929998	40930021	15	-	28162770	SKM1	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	-2.669998604576956	[17]	[4]	-9	hSpCas9	negative selection	10483410
40931596	40931619	15	-	28162770	SKM1	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.44832322850421924	[114]	[148]	-4	hSpCas9	negative selection	10483411
40935004	40935027	15	+	28162770	SKM1	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.30426207462416743	[81]	[178]	3	hSpCas9	negative selection	10483412
40936465	40936488	15	-	28162770	SKM1	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.7065244806020692	[11]	[12]	-5	hSpCas9	negative selection	10483413
40936546	40936569	15	-	28162770	SKM1	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	0.40039072331444236	[8]	[20]	4	hSpCas9	negative selection	10483414
40930043	40930066	15	-	28162770	SKM1	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.031924767396236925	[47]	[82]	0	hSpCas9	negative selection	10652771
40936568	40936591	15	-	28162770	SKM1	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	0.15938262381064755	[38]	[76]	1	hSpCas9	negative selection	10652772
40936529	40936552	15	+	28162770	SKM1	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.20184504393236202	[89]	[182]	2	hSpCas9	negative selection	10652773
40929691	40929714	15	-	28162770	SKM1	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.7697181688744597	[70]	[213]	7	hSpCas9	negative selection	10652774
40929954	40929977	15	-	28162770	SKM1	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.01753362978474826	[37]	[67]	0	hSpCas9	negative selection	10652775
40929998	40930021	15	-	28162770	SKM1	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	-2.669998604576956	[17]	[4]	-9	hSpCas9	negative selection	10652776
40931596	40931619	15	-	28162770	SKM1	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.44832322850421924	[114]	[148]	-4	hSpCas9	negative selection	10652777
40935004	40935027	15	+	28162770	SKM1	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.30426207462416743	[81]	[178]	3	hSpCas9	negative selection	10652778
40936465	40936488	15	-	28162770	SKM1	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.7065244806020692	[11]	[12]	-5	hSpCas9	negative selection	10652779
40936546	40936569	15	-	28162770	SKM1	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	0.40039072331444236	[8]	[20]	4	hSpCas9	negative selection	10652780
40930043	40930066	15	-	28162770	PL21	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	0.48716950139209225	[158]	[96]	4	hSpCas9	negative selection	10822137
40936568	40936591	15	-	28162770	PL21	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-1.00373271887633	[128]	[27]	-6	hSpCas9	negative selection	10822138
40936529	40936552	15	+	28162770	PL21	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	1.6434661581995877	[302]	[411]	9	hSpCas9	negative selection	10822139
40929691	40929714	15	-	28162770	PL21	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.46707847477902986	[245]	[147]	4	hSpCas9	negative selection	10822140
40929954	40929977	15	-	28162770	PL21	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	-0.14381478672804127	[98]	[38]	-1	hSpCas9	negative selection	10822141
40929998	40930021	15	-	28162770	PL21	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.9200316952965848	[50]	[41]	7	hSpCas9	negative selection	10822142
40931596	40931619	15	-	28162770	PL21	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	0.1352884701393523	[363]	[173]	1	hSpCas9	negative selection	10822143
40935004	40935027	15	+	28162770	PL21	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	-0.022252806847127937	[342]	[146]	0	hSpCas9	negative selection	10822144
40936465	40936488	15	-	28162770	PL21	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	0.7851021152104762	[51]	[38]	6	hSpCas9	negative selection	10822145
40936546	40936569	15	-	28162770	PL21	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	-2.2592920041479774	[21]	[1]	-8	hSpCas9	negative selection	10822146
40930043	40930066	15	-	28162770	P31FUJ	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.8057920634694586	[179]	[120]	-6	hSpCas9	negative selection	10991503
40936568	40936591	15	-	28162770	P31FUJ	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-1.146214519418288	[193]	[102]	-7	hSpCas9	negative selection	10991504
40936529	40936552	15	+	28162770	P31FUJ	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.27108868565945976	[243]	[345]	3	hSpCas9	negative selection	10991505
40929691	40929714	15	-	28162770	P31FUJ	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.08358770693155365	[260]	[324]	0	hSpCas9	negative selection	10991506
40929954	40929977	15	-	28162770	P31FUJ	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.4600162860674455	[72]	[117]	5	hSpCas9	negative selection	10991507
40929998	40930021	15	-	28162770	P31FUJ	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.6602825916691097	[20]	[38]	7	hSpCas9	negative selection	10991508
40931596	40931619	15	-	28162770	P31FUJ	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.5426574670011661	[356]	[287]	-4	hSpCas9	negative selection	10991509
40935004	40935027	15	+	28162770	P31FUJ	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.14126351380815905	[499]	[647]	1	hSpCas9	negative selection	10991510
40936465	40936488	15	-	28162770	P31FUJ	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.6416077499817081	[76]	[57]	-5	hSpCas9	negative selection	10991511
40936546	40936569	15	-	28162770	P31FUJ	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	2.0330918555586557	[20]	[100]	9	hSpCas9	negative selection	10991512
40930043	40930066	15	-	28162770	OCIAML5	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.3057845383069006	[125]	[183]	-2	hSpCas9	negative selection	11160869
40936568	40936591	15	-	28162770	OCIAML5	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.23374547319640987	[113]	[174]	-2	hSpCas9	negative selection	11160870
40936529	40936552	15	+	28162770	OCIAML5	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.7373011089771604	[108]	[327]	6	hSpCas9	negative selection	11160871
40929691	40929714	15	-	28162770	OCIAML5	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.7694218058822732	[116]	[359]	6	hSpCas9	negative selection	11160872
40929954	40929977	15	-	28162770	OCIAML5	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.2611440395839939	[48]	[105]	2	hSpCas9	negative selection	11160873
40929998	40930021	15	-	28162770	OCIAML5	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.37032585047245115	[26]	[62]	3	hSpCas9	negative selection	11160874
40931596	40931619	15	-	28162770	OCIAML5	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.08207217631031982	[284]	[485]	0	hSpCas9	negative selection	11160875
40935004	40935027	15	+	28162770	OCIAML5	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.367954946009704	[260]	[607]	3	hSpCas9	negative selection	11160876
40936465	40936488	15	-	28162770	OCIAML5	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-1.4370290715851533	[20]	[13]	-7	hSpCas9	negative selection	11160877
40936546	40936569	15	-	28162770	OCIAML5	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	0.5953924061072242	[10]	[29]	5	hSpCas9	negative selection	11160878
40930043	40930066	15	-	28162770	EOL1	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.39738032331682765	[314]	[125]	-3	hSpCas9	negative selection	11330235
40936568	40936591	15	-	28162770	EOL1	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.3851367275620806	[175]	[70]	-3	hSpCas9	negative selection	11330236
40936529	40936552	15	+	28162770	EOL1	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.4035658967512003	[418]	[291]	3	hSpCas9	negative selection	11330237
40929691	40929714	15	-	28162770	EOL1	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.46711480720009546	[540]	[393]	4	hSpCas9	negative selection	11330238
40929954	40929977	15	-	28162770	EOL1	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.0463362519685766	[192]	[104]	0	hSpCas9	negative selection	11330239
40929998	40930021	15	-	28162770	EOL1	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	1.403715608269094	[65]	[91]	9	hSpCas9	negative selection	11330240
40931596	40931619	15	-	28162770	EOL1	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	0.09799928427961979	[453]	[255]	0	hSpCas9	negative selection	11330241
40935004	40935027	15	+	28162770	EOL1	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.4931158340410221	[471]	[349]	4	hSpCas9	negative selection	11330242
40936465	40936488	15	-	28162770	EOL1	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.44628992379777466	[74]	[28]	-3	hSpCas9	negative selection	11330243
40936546	40936569	15	-	28162770	EOL1	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	1.493913417240672	[30]	[45]	9	hSpCas9	negative selection	11330244
40930043	40930066	15	-	28162770	MOLM13	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	0.5536192555704629	[244]	[259]	4	hSpCas9	negative selection	11499601
40936568	40936591	15	-	28162770	MOLM13	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.38737552547441045	[198]	[109]	-2	hSpCas9	negative selection	11499602
40936529	40936552	15	+	28162770	MOLM13	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	1.3702183039217108	[358]	[670]	9	hSpCas9	negative selection	11499603
40929691	40929714	15	-	28162770	MOLM13	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.013510990633566797	[284]	[207]	0	hSpCas9	negative selection	11499604
40929954	40929977	15	-	28162770	MOLM13	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.8847848270440051	[193]	[258]	6	hSpCas9	negative selection	11499605
40929998	40930021	15	-	28162770	MOLM13	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	1.6184490581199604	[49]	[110]	9	hSpCas9	negative selection	11499606
40931596	40931619	15	-	28162770	MOLM13	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.2699804401917415	[531]	[318]	-2	hSpCas9	negative selection	11499607
40935004	40935027	15	+	28162770	MOLM13	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	1.2614385040771525	[419]	[727]	8	hSpCas9	negative selection	11499608
40936465	40936488	15	-	28162770	MOLM13	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-1.4496484582634483	[67]	[17]	-6	hSpCas9	negative selection	11499609
40936546	40936569	15	-	28162770	MOLM13	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	-0.910622241709151	[38]	[14]	-5	hSpCas9	negative selection	11499610
40930043	40930066	15	-	28162770	HEL	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-1.4567968415505577	[239]	[55]	-7	hSpCas9	negative selection	11668967
40936568	40936591	15	-	28162770	HEL	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.33477715384826395	[190]	[96]	-2	hSpCas9	negative selection	11668968
40936529	40936552	15	+	28162770	HEL	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.8747300581467182	[320]	[376]	7	hSpCas9	negative selection	11668969
40929691	40929714	15	-	28162770	HEL	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	-0.2884391352552054	[306]	[160]	-2	hSpCas9	negative selection	11668970
40929954	40929977	15	-	28162770	HEL	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	-0.12460041120936804	[159]	[93]	-1	hSpCas9	negative selection	11668971
40929998	40930021	15	-	28162770	HEL	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	-0.49476469174957804	[43]	[19]	-3	hSpCas9	negative selection	11668972
40931596	40931619	15	-	28162770	HEL	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	0.4411049708307063	[436]	[379]	3	hSpCas9	negative selection	11668973
40935004	40935027	15	+	28162770	HEL	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.033730857312549656	[362]	[237]	0	hSpCas9	negative selection	11668974
40936465	40936488	15	-	28162770	HEL	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.5552005456115519	[77]	[33]	-4	hSpCas9	negative selection	11668975
40936546	40936569	15	-	28162770	HEL	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	0.4621665863585358	[16]	[14]	4	hSpCas9	negative selection	11668976
40930043	40930066	15	-	28162770	MV411	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	0.006429451278980369	[142]	[120]	0	hSpCas9	negative selection	11838333
40936568	40936591	15	-	28162770	MV411	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	0.3405469551742568	[119]	[127]	3	hSpCas9	negative selection	11838334
40936529	40936552	15	+	28162770	MV411	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.9934862497114199	[284]	[477]	8	hSpCas9	negative selection	11838335
40929691	40929714	15	-	28162770	MV411	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.3128906122713914	[236]	[247]	2	hSpCas9	negative selection	11838336
40929954	40929977	15	-	28162770	MV411	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.5782620461585339	[96]	[121]	5	hSpCas9	negative selection	11838337
40929998	40930021	15	-	28162770	MV411	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.32338640401607366	[36]	[38]	3	hSpCas9	negative selection	11838338
40931596	40931619	15	-	28162770	MV411	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	0.19852795030182901	[329]	[318]	1	hSpCas9	negative selection	11838339
40935004	40935027	15	+	28162770	MV411	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	-0.9292926285646514	[424]	[187]	-6	hSpCas9	negative selection	11838340
40936465	40936488	15	-	28162770	MV411	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-2.5133747853377986	[60]	[8]	-8	hSpCas9	negative selection	11838341
40936546	40936569	15	-	28162770	MV411	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	1.692222393455671	[17]	[48]	9	hSpCas9	negative selection	11838342
40930043	40930066	15	-	28162770	MONOMAC1	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	0.5625301760437851	[113]	[192]	5	hSpCas9	negative selection	12007699
40936568	40936591	15	-	28162770	MONOMAC1	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.2965725206104681	[89]	[83]	-3	hSpCas9	negative selection	12007700
40936529	40936552	15	+	28162770	MONOMAC1	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.1461077337375044	[215]	[273]	1	hSpCas9	negative selection	12007701
40929691	40929714	15	-	28162770	MONOMAC1	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.4029695338860525	[158]	[240]	4	hSpCas9	negative selection	12007702
40929954	40929977	15	-	28162770	MONOMAC1	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	-0.5662706567252727	[61]	[47]	-5	hSpCas9	negative selection	12007703
40929998	40930021	15	-	28162770	MONOMAC1	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	-0.48654346425453854	[21]	[17]	-4	hSpCas9	negative selection	12007704
40931596	40931619	15	-	28162770	MONOMAC1	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	0.1710502372927204	[202]	[261]	1	hSpCas9	negative selection	12007705
40935004	40935027	15	+	28162770	MONOMAC1	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	1.0323547149466041	[234]	[550]	8	hSpCas9	negative selection	12007706
40936465	40936488	15	-	28162770	MONOMAC1	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-0.30013034002365746	[28]	[26]	-3	hSpCas9	negative selection	12007707
40936546	40936569	15	-	28162770	MONOMAC1	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	0.10781773446886689	[16]	[20]	1	hSpCas9	negative selection	12007708
40930043	40930066	15	-	28162770	OCIAML2	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	0.3513718727798441	[27]	[197]	3	hSpCas9	negative selection	12177065
40936568	40936591	15	-	28162770	OCIAML2	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.5563596992680453	[25]	[97]	-4	hSpCas9	negative selection	12177066
40936529	40936552	15	+	28162770	OCIAML2	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	0.48994002992930086	[50]	[396]	5	hSpCas9	negative selection	12177067
40929691	40929714	15	-	28162770	OCIAML2	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	0.7827111843877885	[27]	[266]	7	hSpCas9	negative selection	12177068
40929954	40929977	15	-	28162770	OCIAML2	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	0.8592910603987319	[17]	[180]	8	hSpCas9	negative selection	12177069
40929998	40930021	15	-	28162770	OCIAML2	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	0.04033209403521831	[9]	[56]	0	hSpCas9	negative selection	12177070
40931596	40931619	15	-	28162770	OCIAML2	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.5516295473556481	[86]	[328]	-4	hSpCas9	negative selection	12177071
40935004	40935027	15	+	28162770	OCIAML2	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	-0.13157755256358983	[66]	[338]	-1	hSpCas9	negative selection	12177072
40936465	40936488	15	-	28162770	OCIAML2	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	-1.470629825242161	[4]	[9]	-7	hSpCas9	negative selection	12177073
40936546	40936569	15	-	28162770	OCIAML2	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	2.699295176200151	[0]	[35]	9	hSpCas9	negative selection	12177074
40930043	40930066	15	-	28162770	OCIAML3	viability	ACTGTCGTCCCGGACAGCGAAGG	DLL4	ENSG00000128917	-0.11453826845032088	[51]	[144]	-1	hSpCas9	negative selection	12346431
40936568	40936591	15	-	28162770	OCIAML3	viability	CCAGCGAGACGGCCACCCAGGGG	DLL4	ENSG00000128917	-0.2561380015677792	[35]	[90]	-2	hSpCas9	negative selection	12346432
40936529	40936552	15	+	28162770	OCIAML3	viability	CAGCCGCTGCGAGTTCCCCGTGG	DLL4	ENSG00000128917	-0.09868235208768361	[82]	[233]	-1	hSpCas9	negative selection	12346433
40929691	40929714	15	-	28162770	OCIAML3	viability	CAGCAGTAGCGCCCAGCCAGAGG	DLL4	ENSG00000128917	1.1253322831602086	[69]	[460]	8	hSpCas9	negative selection	12346434
40929954	40929977	15	-	28162770	OCIAML3	viability	GGAAGTGCTTAAGGCAGACGCGG	DLL4	ENSG00000128917	-0.6895853003063943	[38]	[72]	-5	hSpCas9	negative selection	12346435
40929998	40930021	15	-	28162770	OCIAML3	viability	GGAGACGGTCCCGAAGGTGCAGG	DLL4	ENSG00000128917	-0.4565041165742283	[9]	[21]	-4	hSpCas9	negative selection	12346436
40931596	40931619	15	-	28162770	OCIAML3	viability	AGAGTAGCGCAGCCTTGTGAGGG	DLL4	ENSG00000128917	-0.7477170557196163	[93]	[168]	-5	hSpCas9	negative selection	12346437
40935004	40935027	15	+	28162770	OCIAML3	viability	CCTGCCGGGAGCGCAACCAGGGG	DLL4	ENSG00000128917	0.720307270453324	[113]	[566]	6	hSpCas9	negative selection	12346438
40936465	40936488	15	-	28162770	OCIAML3	viability	GGAGAGGTCGGTGTAGCAGGTGG	DLL4	ENSG00000128917	1.2639733548034089	[11]	[86]	9	hSpCas9	negative selection	12346439
40936546	40936569	15	-	28162770	OCIAML3	viability	GAAGCTGGGCGGCAAGCCCACGG	DLL4	ENSG00000128917	0.9084927002050196	[2]	[16]	7	hSpCas9	negative selection	12346440