Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5610
• Symbol:EIF2AK2
• Description:eukaryotic translation initiation factor 2 alpha kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/EIF2AK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
37138547	37138570	2	+	26472758	Jiyoye	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.557418017086486	[163]	[181]	4	hSpCas9	negative selection	49162
37138340	37138363	2	-	26472758	Jiyoye	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	-0.22944923903777542	[198]	[127]	-2	hSpCas9	negative selection	49163
37122636	37122659	2	-	26472758	Jiyoye	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	-0.038135128886771064	[304]	[223]	0	hSpCas9	negative selection	49164
37146929	37146952	2	-	26472758	Jiyoye	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.9773104645493904	[162]	[241]	6	hSpCas9	negative selection	49165
37141630	37141653	2	+	26472758	Jiyoye	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	1.0142316530776465	[215]	[328]	6	hSpCas9	negative selection	49166
37109241	37109264	2	+	26472758	Jiyoye	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	-0.17778711921528279	[71]	[47]	-1	hSpCas9	negative selection	49167
37147734	37147757	2	+	26472758	Jiyoye	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.1238685806458184	[386]	[317]	0	hSpCas9	negative selection	49168
37122544	37122567	2	+	26472758	Jiyoye	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	1.61153388001206	[22]	[52]	8	hSpCas9	negative selection	49169
37147679	37147702	2	+	26472758	Jiyoye	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.015681622232269654	[184]	[137]	0	hSpCas9	negative selection	49170
37141570	37141593	2	-	26472758	Jiyoye	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	1.6951561444698982	[85]	[209]	8	hSpCas9	negative selection	49171
37138547	37138570	2	+	26472758	KBM7	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.23371685568599893	[630,481]	[267,337]	2	hSpCas9	negative selection	240280
37138340	37138363	2	-	26472758	KBM7	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.010899146119150771	[534,743]	[384,241]	0	hSpCas9	negative selection	240281
37122636	37122659	2	-	26472758	KBM7	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.2459199563907939	[1168,978]	[542,643]	2	hSpCas9	negative selection	240282
37146929	37146952	2	-	26472758	KBM7	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.8971361877431147	[556,428]	[473,386]	8	hSpCas9	negative selection	240283
37141630	37141653	2	+	26472758	KBM7	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.8162815585618527	[1099,682]	[1015,462]	8	hSpCas9	negative selection	240284
37109241	37109264	2	+	26472758	KBM7	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	1.357684203822877	[127,100]	[127,144]	9	hSpCas9	negative selection	240285
37147734	37147757	2	+	26472758	KBM7	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.7567800449060531	[1976,2036]	[513,604]	-6	hSpCas9	negative selection	240286
37122544	37122567	2	+	26472758	KBM7	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.8753184431327763	[146,182]	[189,103]	8	hSpCas9	negative selection	240287
37147679	37147702	2	+	26472758	KBM7	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.48145672334970624	[797,1121]	[302,354]	-4	hSpCas9	negative selection	240288
37141570	37141593	2	-	26472758	KBM7	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.5281351186063079	[1058,986]	[429,930]	6	hSpCas9	negative selection	240289
37138547	37138570	2	+	26472758	Raji	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.9325093179595537	[218]	[96]	8	hSpCas9	negative selection	431398
37138340	37138363	2	-	26472758	Raji	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.102825253411295	[316]	[78]	1	hSpCas9	negative selection	431399
37122636	37122659	2	-	26472758	Raji	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	-0.1543339419882035	[656]	[136]	-1	hSpCas9	negative selection	431400
37146929	37146952	2	-	26472758	Raji	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.05374557177152639	[410]	[98]	0	hSpCas9	negative selection	431401
37141630	37141653	2	+	26472758	Raji	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.47359855606776935	[570]	[183]	4	hSpCas9	negative selection	431402
37109241	37109264	2	+	26472758	Raji	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.19665087347068688	[93]	[24]	1	hSpCas9	negative selection	431403
37147734	37147757	2	+	26472758	Raji	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.5598957400711064	[721]	[246]	5	hSpCas9	negative selection	431404
37122544	37122567	2	+	26472758	Raji	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	-0.3166427471324992	[160]	[29]	-3	hSpCas9	negative selection	431405
37147679	37147702	2	+	26472758	Raji	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.17614918077675246	[481]	[98]	-1	hSpCas9	negative selection	431406
37141570	37141593	2	-	26472758	Raji	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.5312448850394496	[488]	[163]	5	hSpCas9	negative selection	431407
37138547	37138570	2	+	26472758	K562	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	1.9523206781732676	[355]	[1162]	9	hSpCas9	negative selection	622516
37138340	37138363	2	-	26472758	K562	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.8223656777194559	[480]	[717]	6	hSpCas9	negative selection	622517
37122636	37122659	2	-	26472758	K562	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	-0.051415171069771226	[1040]	[847]	0	hSpCas9	negative selection	622518
37146929	37146952	2	-	26472758	K562	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.9617476570321943	[502]	[826]	7	hSpCas9	negative selection	622519
37141630	37141653	2	+	26472758	K562	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.32537964418404963	[640]	[677]	2	hSpCas9	negative selection	622520
37109241	37109264	2	+	26472758	K562	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	1.0896961328678048	[117]	[211]	8	hSpCas9	negative selection	622521
37147734	37147757	2	+	26472758	K562	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.03358078931417152	[1220]	[1006]	0	hSpCas9	negative selection	622522
37122544	37122567	2	+	26472758	K562	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.5427600022361934	[147]	[181]	4	hSpCas9	negative selection	622523
37147679	37147702	2	+	26472758	K562	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2018606819569021	[777]	[570]	-1	hSpCas9	negative selection	622524
37141570	37141593	2	-	26472758	K562	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.06992099643431038	[868]	[769]	0	hSpCas9	negative selection	622525
37109265	37109288	2	-	26627737	DLD1	viability	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.6606038815472326	[370]	[76,69,72]	-6	hSpCas9	negative selection	811844
37114730	37114753	2	-	26627737	DLD1	viability	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.05572665502499552	[907]	[338,126,395]	0	hSpCas9	negative selection	811845
37120121	37120144	2	+	26627737	DLD1	viability	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-1.7518906873940492	[296]	[42,28,12]	-8	hSpCas9	negative selection	811846
37109265	37109288	2	-	26627737	GBM cells	viability after 5 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.21695504768888818	[222]	[115,161]	3	hSpCas9	negative selection	894159
37114730	37114753	2	-	26627737	GBM cells	viability after 5 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.35086923362932954	[597]	[444,372]	5	hSpCas9	negative selection	894160
37120121	37120144	2	+	26627737	GBM cells	viability after 5 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.28106479122054984	[161]	[58,83]	-4	hSpCas9	negative selection	894161
37109265	37109288	2	-	26627737	GBM cells	viability after 13 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.4532360397090653	[222]	[163,166]	6	hSpCas9	negative selection	976474
37114730	37114753	2	-	26627737	GBM cells	viability after 13 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.4588586330252382	[597]	[499,401]	6	hSpCas9	negative selection	976475
37120121	37120144	2	+	26627737	GBM cells	viability after 13 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	0.0717985070954481	[161]	[98,86]	0	hSpCas9	negative selection	976476
37109265	37109288	2	-	26627737	GBM cells	viability after 21 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.4460441663380479	[222]	[163,165]	4	hSpCas9	negative selection	1058789
37114730	37114753	2	-	26627737	GBM cells	viability after 21 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.6656870435231814	[597]	[541,490]	6	hSpCas9	negative selection	1058790
37120121	37120144	2	+	26627737	GBM cells	viability after 21 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.20516543189733594	[161]	[79,72]	-2	hSpCas9	negative selection	1058791
37109265	37109288	2	-	26627737	RPE1	viability after 9 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-1.5570787685117966	[1409]	[156,140]	-8	hSpCas9	negative selection	1141104
37114730	37114753	2	-	26627737	RPE1	viability after 9 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.09883238727428223	[2540]	[747,985]	0	hSpCas9	negative selection	1141105
37120121	37120144	2	+	26627737	RPE1	viability after 9 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.12146050671998787	[373]	[80,141]	-1	hSpCas9	negative selection	1141106
37109265	37109288	2	-	26627737	RPE1	viability after 12 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.8804691683677041	[1409]	[214,195]	-6	hSpCas9	negative selection	1223419
37114730	37114753	2	-	26627737	RPE1	viability after 12 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.10900755895187575	[2540]	[547,722]	0	hSpCas9	negative selection	1223420
37120121	37120144	2	+	26627737	RPE1	viability after 12 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.8776909506734396	[373]	[43,65]	-6	hSpCas9	negative selection	1223421
37109265	37109288	2	-	26627737	RPE1	viability after 15 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-1.3086109756341728	[1409]	[215,107]	-7	hSpCas9	negative selection	1305734
37114730	37114753	2	-	26627737	RPE1	viability after 15 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.09214433828183233	[2540]	[571,772]	0	hSpCas9	negative selection	1305735
37120121	37120144	2	+	26627737	RPE1	viability after 15 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	0.008705633854444006	[373]	[109,102]	0	hSpCas9	negative selection	1305736
37109265	37109288	2	-	26627737	RPE1	viability after 18 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-1.028357818344127	[1409]	[260,106]	-6	hSpCas9	negative selection	1388049
37114730	37114753	2	-	26627737	RPE1	viability after 18 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.15600592029767468	[2540]	[779,746]	1	hSpCas9	negative selection	1388050
37120121	37120144	2	+	26627737	RPE1	viability after 18 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	0.014796885095451628	[373]	[71,133]	0	hSpCas9	negative selection	1388051
37109265	37109288	2	-	26627737	HeLa	viability after 8 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.7974806935235901	[197]	[258,89,125]	6	hSpCas9	negative selection	1470364
37114730	37114753	2	-	26627737	HeLa	viability after 8 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.1254976595776991	[1365]	[612,541,497]	-1	hSpCas9	negative selection	1470365
37120121	37120144	2	+	26627737	HeLa	viability after 8 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	0.5138337071064012	[129]	[87,46,106]	4	hSpCas9	negative selection	1470366
37109265	37109288	2	-	26627737	HeLa	viability after 12 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	1.055332770892299	[197]	[256,100,161]	7	hSpCas9	negative selection	1552679
37114730	37114753	2	-	26627737	HeLa	viability after 12 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.2979147402337694	[1365]	[444,441,491]	-3	hSpCas9	negative selection	1552680
37120121	37120144	2	+	26627737	HeLa	viability after 12 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	0.34955734185355714	[129]	[31,42,131]	3	hSpCas9	negative selection	1552681
37109265	37109288	2	-	26627737	HeLa	viability after 15 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	1.115242145605586	[197]	[121,173,232]	7	hSpCas9	negative selection	1634994
37114730	37114753	2	-	26627737	HeLa	viability after 15 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.10274236285461646	[1365]	[624,508,409]	-1	hSpCas9	negative selection	1634995
37120121	37120144	2	+	26627737	HeLa	viability after 15 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.12928099384220282	[129]	[33,42,69]	-1	hSpCas9	negative selection	1634996
37109265	37109288	2	-	26627737	HeLa	viability after 18 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	1.14999259249133	[197]	[90,142,232]	7	hSpCas9	negative selection	1717309
37114730	37114753	2	-	26627737	HeLa	viability after 18 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.0909421589771282	[1365]	[419,430,409]	-1	hSpCas9	negative selection	1717310
37120121	37120144	2	+	26627737	HeLa	viability after 18 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.09141556583418153	[129]	[24,35,69]	-1	hSpCas9	negative selection	1717311
37109265	37109288	2	-	26627737	HCT116	viability after 6 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.4981232626710582	[411]	[17,131]	2	hSpCas9	negative selection	1799624
37114730	37114753	2	-	26627737	HCT116	viability after 6 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.8919240455023796	[1633]	[437,497]	5	hSpCas9	negative selection	1799625
37120121	37120144	2	+	26627737	HCT116	viability after 6 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.1738628674717981	[634]	[63,101]	-1	hSpCas9	negative selection	1799626
37109265	37109288	2	-	26627737	HCT116	viability after 8 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.7833367970921806	[389]	[118,90,163]	-7	hSpCas9	negative selection	1881939
37114730	37114753	2	-	26627737	HCT116	viability after 8 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.1745422048951777	[871]	[410,627,584]	2	hSpCas9	negative selection	1881940
37120121	37120144	2	+	26627737	HCT116	viability after 8 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.7350256552608687	[165]	[49,77,36]	-7	hSpCas9	negative selection	1881941
37109265	37109288	2	-	26627737	HCT116	viability after 9 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.04247517020112157	[411]	[160,63]	0	hSpCas9	negative selection	1964254
37114730	37114753	2	-	26627737	HCT116	viability after 9 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.046071953131873844	[1633]	[559,313]	0	hSpCas9	negative selection	1964255
37120121	37120144	2	+	26627737	HCT116	viability after 9 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.25825759437763535	[634]	[143,139]	-2	hSpCas9	negative selection	1964256
37109265	37109288	2	-	26627737	HCT116	viability after 12 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.1063876932366985	[389]	[83,210,285]	-1	hSpCas9	negative selection	2046569
37114730	37114753	2	-	26627737	HCT116	viability after 12 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.04658275002536438	[871]	[341,524,474]	0	hSpCas9	negative selection	2046570
37120121	37120144	2	+	26627737	HCT116	viability after 12 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.3567875695278331	[165]	[56,94,53]	-4	hSpCas9	negative selection	2046571
37109265	37109288	2	-	26627737	HCT116	viability after 15 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.3093911366712458	[389]	[193,181,167]	-3	hSpCas9	negative selection	2128884
37114730	37114753	2	-	26627737	HCT116	viability after 15 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.09094260442876112	[871]	[648,416,547]	0	hSpCas9	negative selection	2128885
37120121	37120144	2	+	26627737	HCT116	viability after 15 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.9061153445545995	[165]	[29,62,56]	-7	hSpCas9	negative selection	2128886
37109265	37109288	2	-	26627737	HCT116	viability after 18 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.16925593706456257	[389]	[167,201,128]	-1	hSpCas9	negative selection	2211199
37114730	37114753	2	-	26627737	HCT116	viability after 18 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.01628022589780098	[871]	[272,506,496]	0	hSpCas9	negative selection	2211200
37120121	37120144	2	+	26627737	HCT116	viability after 18 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-1.1664294182501138	[165]	[22,8,78]	-8	hSpCas9	negative selection	2211201
37146947	37146970	2	-	24336569	HL60	viability	ACATTTCAAGTTATAATAGATGG	EIF2AK2	ENSG00000055332	-0.21896762437883105	[582]	[1059]	-2	hSpCas9	negative selection	2262329
37147679	37147702	2	+	24336569	HL60	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	0.4345510463747684	[299]	[857]	4	hSpCas9	negative selection	2262330
37147687	37147710	2	-	24336569	HL60	viability	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	-0.24958685943722325	[1049]	[1868]	-2	hSpCas9	negative selection	2262331
37147694	37147717	2	+	24336569	HL60	viability	TCATGTGGAGGTCCTGAATTAGG	EIF2AK2	ENSG00000055332	0.4883072930616029	[540]	[1605]	4	hSpCas9	negative selection	2262332
37147706	37147729	2	-	24336569	HL60	viability	TATCAAGAACTGCCTAATTCAGG	EIF2AK2	ENSG00000055332	0.4585382590012248	[955]	[2779]	4	hSpCas9	negative selection	2262333
37147734	37147757	2	+	24336569	HL60	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.5844240884812046	[653]	[922]	-5	hSpCas9	negative selection	2262334
37147742	37147765	2	-	24336569	HL60	viability	AATACATACCGTCAGAAGCAGGG	EIF2AK2	ENSG00000055332	1.4200823919046224	[622]	[3527]	8	hSpCas9	negative selection	2262335
37147770	37147793	2	-	24336569	HL60	viability	TTCAGCAGGTTTCTTCATGGAGG	EIF2AK2	ENSG00000055332	0.4412141218379173	[141]	[407]	4	hSpCas9	negative selection	2262336
37147784	37147807	2	-	24336569	HL60	viability	ATGGCTGGTGATCTTTCAGCAGG	EIF2AK2	ENSG00000055332	-0.5813904974942533	[769]	[1088]	-5	hSpCas9	negative selection	2262337
37147799	37147822	2	-	24336569	HL60	viability	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	0.41025139304524105	[931]	[2620]	4	hSpCas9	negative selection	2262338
37146947	37146970	2	-	24336569	KBM7	viability	ACATTTCAAGTTATAATAGATGG	EIF2AK2	ENSG00000055332	-0.30732506178291286	[523]	[1154]	-3	hSpCas9	negative selection	2329506
37147679	37147702	2	+	24336569	KBM7	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.053536680845589976	[397]	[1045]	0	hSpCas9	negative selection	2329507
37147687	37147710	2	-	24336569	KBM7	viability	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	1.1633785127052183	[329]	[2015]	8	hSpCas9	negative selection	2329508
37147694	37147717	2	+	24336569	KBM7	viability	TCATGTGGAGGTCCTGAATTAGG	EIF2AK2	ENSG00000055332	1.1293945369936793	[331]	[1980]	8	hSpCas9	negative selection	2329509
37147706	37147729	2	-	24336569	KBM7	viability	TATCAAGAACTGCCTAATTCAGG	EIF2AK2	ENSG00000055332	0.29462304598347067	[769]	[2575]	2	hSpCas9	negative selection	2329510
37147734	37147757	2	+	24336569	KBM7	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.21718401538539328	[421]	[1337]	2	hSpCas9	negative selection	2329511
37147742	37147765	2	-	24336569	KBM7	viability	AATACATACCGTCAGAAGCAGGG	EIF2AK2	ENSG00000055332	0.06228184893155486	[1057]	[3012]	0	hSpCas9	negative selection	2329512
37147770	37147793	2	-	24336569	KBM7	viability	TTCAGCAGGTTTCTTCATGGAGG	EIF2AK2	ENSG00000055332	1.5542320968979402	[198]	[1593]	9	hSpCas9	negative selection	2329513
37147784	37147807	2	-	24336569	KBM7	viability	ATGGCTGGTGATCTTTCAGCAGG	EIF2AK2	ENSG00000055332	0.7250755976490022	[351]	[1586]	6	hSpCas9	negative selection	2329514
37147799	37147822	2	-	24336569	KBM7	viability	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	-0.7564806111400055	[1322]	[2135]	-5	hSpCas9	negative selection	2329515
37147975	37147998	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTGAATGAGAAAGAAAGAACGG	EIF2AK2	ENSG00000055332	2.058180228475923	[122,121]	[180,38]	7	dCas9-VP64	positive selection	2399453
37147920	37147943	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGAGATGAGTCCTATAAAGGGG	EIF2AK2	ENSG00000055332	-0.3161944097467669	[7,271]	[7,41]	-1	dCas9-VP64	positive selection	2399454
37147909	37147932	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGGGGAGACTCCCCTTTATAGG	EIF2AK2	ENSG00000055332	1.2714846016164578	[110,56]	[79,4]	5	dCas9-VP64	positive selection	2399455
37116343	37116366	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCTGTGGTCCCAGCTACTTGG	EIF2AK2	ENSG00000055332	-1.0019767452838857	[448,49]	[42,8]	-6	dCas9-VP64	positive selection	2399857
37115938	37115961	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATGCCACTACACTCCATCCTGG	EIF2AK2	ENSG00000055332	1.9286097489754745	[415,203]	[114,413]	6	dCas9-VP64	positive selection	2407201
37113453	37113476	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCATTGCACTCCAGCCTTGG	EIF2AK2	ENSG00000055332	2.033062228314259	[28,209]	[4,221]	7	dCas9-VP64	positive selection	2456532
37147975	37147998	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTGAATGAGAAAGAAAGAACGG	EIF2AK2	ENSG00000055332	1.0677260506513033	[58,263]	[22,189]	6	dCas9-VP64	positive selection	2494708
37147920	37147943	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGAGATGAGTCCTATAAAGGGG	EIF2AK2	ENSG00000055332	-0.10787974714969117	[56,256]	[48,44]	-1	dCas9-VP64	positive selection	2494709
37147909	37147932	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGGGGAGACTCCCCTTTATAGG	EIF2AK2	ENSG00000055332	2.2447166668565237	[75,223]	[33,414]	8	dCas9-VP64	positive selection	2494710
37116343	37116366	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCTGTGGTCCCAGCTACTTGG	EIF2AK2	ENSG00000055332	0.3516116254360768	[311,292]	[125,125]	3	dCas9-VP64	positive selection	2495112
37115938	37115961	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATGCCACTACACTCCATCCTGG	EIF2AK2	ENSG00000055332	-0.26102272442263375	[369,548]	[99,147]	-2	dCas9-VP64	positive selection	2502456
37113453	37113476	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCATTGCACTCCAGCCTTGG	EIF2AK2	ENSG00000055332	0.2042793589460996	[254,297]	[44,158]	1	dCas9-VP64	positive selection	2551787
37146868	37146891	2	+	27013184	SW480	treatment with recombinant TRAIL	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-1.0804926268220114	[86,82]	[4,34]	-5	hSpCas9	positive selection	2954607
37146874	37146897	2	+	27013184	SW480	treatment with recombinant TRAIL	CTCAACAGCTAATTTGGCTGCGG	EIF2AK2	ENSG00000055332	-4.022822377293913	[222,663]	[2,22]	-9	hSpCas9	positive selection	2954608
37141630	37141653	2	+	27013184	SW480	treatment with recombinant TRAIL	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	-1.1973758554194203	[465,581]	[76,126]	-5	hSpCas9	positive selection	2954609
37147690	37147713	2	-	27013184	SW480	treatment with recombinant TRAIL	ATTCAGGACCTCCACATGATAGG	EIF2AK2	ENSG00000055332	-0.9638521107064942	[517,1094]	[199,133]	-4	hSpCas9	positive selection	2954610
37147706	37147729	2	-	27013184	SW480	treatment with recombinant TRAIL	TATCAAGAACTGCCTAATTCAGG	EIF2AK2	ENSG00000055332	-1.3013779319644487	[163,241]	[10,68]	-6	hSpCas9	positive selection	2954611
37147742	37147765	2	-	27013184	SW480	treatment with recombinant TRAIL	AATACATACCGTCAGAAGCAGGG	EIF2AK2	ENSG00000055332	-0.07335410530829772	[277,317]	[59,208]	0	hSpCas9	positive selection	2954612
37147743	37147766	2	-	27013184	SW480	treatment with recombinant TRAIL	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.24156479261401342	[10,29]	[7,5]	-1	hSpCas9	positive selection	2954613
37147770	37147793	2	-	27013184	SW480	treatment with recombinant TRAIL	TTCAGCAGGTTTCTTCATGGAGG	EIF2AK2	ENSG00000055332	0.017721175951269763	[237,420]	[120,167]	0	hSpCas9	positive selection	2954614
37147773	37147796	2	-	27013184	SW480	treatment with recombinant TRAIL	TCTTTCAGCAGGTTTCTTCATGG	EIF2AK2	ENSG00000055332	0.1548974692009623	[266,292]	[147,113]	0	hSpCas9	positive selection	2954615
37147784	37147807	2	-	27013184	SW480	treatment with recombinant TRAIL	ATGGCTGGTGATCTTTCAGCAGG	EIF2AK2	ENSG00000055332	0.2037541881482895	[326,347]	[73,299]	1	hSpCas9	positive selection	2954616
37146914	37146937	2	+	27013184	SW480	treatment with recombinant TRAIL	TTTGATCTACCTTCACCTTCTGG	EIF2AK2	ENSG00000055332	-4.247747349769374	[153,88]	[1,3]	-9	hSpCas9	positive selection	2954617
37141561	37141584	2	-	27013184	SW480	treatment with recombinant TRAIL	AGTGTGCATCGGGGGTGCATGGG	EIF2AK2	ENSG00000055332	-0.36903956120442927	[892,987]	[330,286]	-2	hSpCas9	positive selection	2954618
37141562	37141585	2	-	27013184	SW480	treatment with recombinant TRAIL	CAGTGTGCATCGGGGGTGCATGG	EIF2AK2	ENSG00000055332	-2.8538666478449284	[98,106]	[1,11]	-8	hSpCas9	positive selection	2954619
37141569	37141592	2	-	27013184	SW480	treatment with recombinant TRAIL	TTATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-2.721885957395442	[259,450]	[25,17]	-8	hSpCas9	positive selection	2954620
37141570	37141593	2	-	27013184	SW480	treatment with recombinant TRAIL	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	-3.523311526525343	[45,61]	[1,1]	-9	hSpCas9	positive selection	2954621
37141571	37141594	2	-	27013184	SW480	treatment with recombinant TRAIL	AATTATGAACAGTGTGCATCGGG	EIF2AK2	ENSG00000055332	0.835165858216481	[213,178]	[149,155]	4	hSpCas9	positive selection	2954622
37141572	37141595	2	-	27013184	SW480	treatment with recombinant TRAIL	AAATTATGAACAGTGTGCATCGG	EIF2AK2	ENSG00000055332	-0.23169350190531313	[525,353]	[199,113]	-1	hSpCas9	positive selection	2954623
37141634	37141657	2	-	27013184	SW480	treatment with recombinant TRAIL	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.8814236874589905	[93,101]	[26,16]	-4	hSpCas9	positive selection	2954624
37147679	37147702	2	+	27013184	SW480	treatment with recombinant TRAIL	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.4097978807502507	[34,58]	[23,1]	-2	hSpCas9	positive selection	2954625
37141645	37141668	2	-	27013184	SW480	treatment with recombinant TRAIL	CTTCAGAAGGATTATCCATGGGG	EIF2AK2	ENSG00000055332	1.8655970863122764	[23,25]	[39,37]	8	hSpCas9	positive selection	2954626
37141646	37141669	2	-	27013184	SW480	treatment with recombinant TRAIL	TCTTCAGAAGGATTATCCATGGG	EIF2AK2	ENSG00000055332	-1.635113558524282	[103,124]	[9,23]	-6	hSpCas9	positive selection	2954627
37141647	37141670	2	-	27013184	SW480	treatment with recombinant TRAIL	TTCTTCAGAAGGATTATCCATGG	EIF2AK2	ENSG00000055332	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2954628
37147682	37147705	2	+	27013184	SW480	treatment with recombinant TRAIL	ACCTACCTCCTATCATGTGGAGG	EIF2AK2	ENSG00000055332	1.0250600469889206	[531,526]	[328,658]	5	hSpCas9	positive selection	2954629
37147694	37147717	2	+	27013184	SW480	treatment with recombinant TRAIL	TCATGTGGAGGTCCTGAATTAGG	EIF2AK2	ENSG00000055332	0.012678611335550594	[407,726]	[263,207]	0	hSpCas9	positive selection	2954630
37147734	37147757	2	+	27013184	SW480	treatment with recombinant TRAIL	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.8221426732389061	[258,438]	[208,332]	4	hSpCas9	positive selection	2954631
37141593	37141616	2	+	27013184	SW480	treatment with recombinant TRAIL	TTACAGTTAGTCTTTTCTTCTGG	EIF2AK2	ENSG00000055332	-0.46888132723629283	[447,367]	[143,105]	-2	hSpCas9	positive selection	2954632
37146973	37146996	2	-	27013184	SW480	treatment with recombinant TRAIL	TGAATATTCTCTTTGTAATCAGG	EIF2AK2	ENSG00000055332	0.3160013362391636	[46,54]	[13,45]	1	hSpCas9	positive selection	2954633
37147683	37147706	2	-	27013184	SW480	treatment with recombinant TRAIL	ACCTCCACATGATAGGAGGTAGG	EIF2AK2	ENSG00000055332	-0.9397249566793012	[161,115]	[20,46]	-4	hSpCas9	positive selection	2954634
37141611	37141634	2	+	27013184	SW480	treatment with recombinant TRAIL	TCTGGGCAATTCTATTGATAAGG	EIF2AK2	ENSG00000055332	-0.560343160100695	[392,376]	[142,69]	-3	hSpCas9	positive selection	2954635
37147687	37147710	2	-	27013184	SW480	treatment with recombinant TRAIL	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	1.6361484139016964	[460,427]	[695,458]	7	hSpCas9	positive selection	2954636
37147799	37147822	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	0.15923405585042225	[3,3]	[4,3]	3	hSpCas9	positive selection	2985370
37147687	37147710	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	-0.38066487565117	[2,2]	[1,1]	-5	hSpCas9	positive selection	2985371
37146929	37146952	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.17568155770084606	[2,3]	[4,1]	4	hSpCas9	positive selection	2985372
37147735	37147758	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.018285050236326206	[5,5]	[5,3]	0	hSpCas9	positive selection	2985373
37147799	37147822	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	-0.3392570036765421	[3,3]	[2,1]	-5	hSpCas9	positive selection	3053228
37147687	37147710	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	0.32443584167629924	[2,2]	[1,2]	6	hSpCas9	positive selection	3053229
37146929	37146952	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	-0.024027011338129345	[2,2]	[3,0]	0	hSpCas9	positive selection	3053230
37147735	37147758	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.09138035044046877	[5,5]	[4,3]	1	hSpCas9	positive selection	3053231
37146868	37146891		+	24336571	A375	resistance to PLX after 7 days	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.22785915872835732	[18,20]	[16,16]	-7	hSpCas9	positive selection	3111557
37146861	37146884		-	24336571	A375	resistance to PLX after 7 days	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.10414479594032625	[11,12]	[11,11]	-3	hSpCas9	positive selection	3111558
37147743	37147766		-	24336571	A375	resistance to PLX after 7 days	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.15482501396369108	[17,21]	[15,19]	-5	hSpCas9	positive selection	3111559
37146868	37146891		+	24336571	A375	resistance to PLX after 14 days	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.10741394402824417	[17,16]	[6,6]	-1	hSpCas9	positive selection	3169350
37146861	37146884		-	24336571	A375	resistance to PLX after 14 days	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.28367895352985434	[8,10]	[4,5]	3	hSpCas9	positive selection	3169351
37147743	37147766		-	24336571	A375	resistance to PLX after 14 days	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.7836344021216497	[18,21]	[4,5]	-8	hSpCas9	positive selection	3169352
37146868	37146891		+	24336571	A375	viability after 7 days	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.1665432615078553	[17]	[18,20]	2	hSpCas9	negative selection	3227143
37146861	37146884		-	24336571	A375	viability after 7 days	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.21216483946206677	[11]	[11,12]	3	hSpCas9	negative selection	3227144
37147743	37147766		-	24336571	A375	viability after 7 days	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.23091985868778908	[24]	[17,21]	-3	hSpCas9	negative selection	3227145
37146868	37146891		+	24336571	A375	viability after 14 days	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.02636604229161771	[17]	[17,16]	0	hSpCas9	negative selection	3284936
37146861	37146884		-	24336571	A375	viability after 14 days	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.08242723183587292	[11]	[8,10]	-1	hSpCas9	negative selection	3284937
37147743	37147766		-	24336571	A375	viability after 14 days	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.18222653900660968	[24]	[18,21]	-2	hSpCas9	negative selection	3284938
37147743	37147766	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	1.1603269118645771	[60,75]	[0,0]	5	hSpCas9	positive selection	3347639
37141634	37141657	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	4.047017266424414	[318,300]	[0,65]	9	hSpCas9	positive selection	3347640
37141658	37141681	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	3.4913062109982684	[100,61]	[0,10]	9	hSpCas9	positive selection	3347641
37146868	37146891	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	1.1280431945008687	[69,69]	[0,0]	5	hSpCas9	positive selection	3366842
37147679	37147702	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-1.6068599332084452	[465,465]	[0,0]	-9	hSpCas9	positive selection	3366843
37146861	37146884	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.6793117275567355	[244,244]	[0,0]	-5	hSpCas9	positive selection	3366844
37147799	37147822	2	-	26780180	HT29	viability (Avana library 4 designs)	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	0.332963952354329	[]	[]	1	hSpCas9	negative selection	3422179
37147687	37147710	2	-	26780180	HT29	viability (Avana library 4 designs)	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	1.26128534675134	[]	[]	5	hSpCas9	negative selection	3422180
37146929	37146952	2	-	26780180	HT29	viability (Avana library 4 designs)	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.921054126959528	[]	[]	3	hSpCas9	negative selection	3422181
37147734	37147757	2	+	26780180	HT29	viability (Avana library 4 designs)	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.328775931270174	[]	[]	1	hSpCas9	negative selection	3422182
37146929	37146952	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	1.47858186729193	[]	[]	2	hSpCas9	negative selection	3502708
37147734	37147757	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-2.14145300242074	[]	[]	-3	hSpCas9	negative selection	3502709
37147799	37147822	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	1.47314987940106	[]	[]	2	hSpCas9	negative selection	3502710
37147687	37147710	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	5.50384281642623	[]	[]	8	hSpCas9	negative selection	3502711
37141645	37141668	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCAGAAGGATTATCCATGGGG	EIF2AK2	ENSG00000055332	2.55739832800706	[]	[]	4	hSpCas9	negative selection	3502712
37147682	37147705	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTACCTCCTATCATGTGGAGG	EIF2AK2	ENSG00000055332	-2.04301541543516	[]	[]	-2	hSpCas9	negative selection	3502713
37146929	37146952	2	-	26780180	A375	viability (Avana lentiGuide)	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	-3.21617098542558	[]	[]	-5	hSpCas9	negative selection	3611367
37147734	37147757	2	+	26780180	A375	viability (Avana lentiGuide)	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	2.67406717456847	[]	[]	3	hSpCas9	negative selection	3611368
37147799	37147822	2	-	26780180	A375	viability (Avana lentiGuide)	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	14.4688707246602	[]	[]	8	hSpCas9	negative selection	3611369
37147687	37147710	2	-	26780180	A375	viability (Avana lentiGuide)	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	-3.68734809756279	[]	[]	-6	hSpCas9	negative selection	3611370
37141645	37141668	2	-	26780180	A375	viability (Avana lentiGuide)	CTTCAGAAGGATTATCCATGGGG	EIF2AK2	ENSG00000055332	-3.92686319422117	[]	[]	-6	hSpCas9	negative selection	3611371
37147682	37147705	2	+	26780180	A375	viability (Avana lentiGuide)	ACCTACCTCCTATCATGTGGAGG	EIF2AK2	ENSG00000055332	-1.26591770301921	[]	[]	-2	hSpCas9	negative selection	3611372
37146929	37146952	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	-0.22069782007951155	[5]	[4,4]	-3	hSpCas9	positive selection	3720026
37147734	37147757	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.21364118309741856	[6]	[6,4]	-3	hSpCas9	positive selection	3720027
37147799	37147822	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	-0.30944950107852426	[5]	[3,4]	-5	hSpCas9	positive selection	3720028
37147687	37147710	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	0.29338234749798664	[4]	[4,5]	8	hSpCas9	positive selection	3720029
37141645	37141668	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCAGAAGGATTATCCATGGGG	EIF2AK2	ENSG00000055332	0.18478399068795565	[5]	[6,5]	5	hSpCas9	positive selection	3720030
37147682	37147705	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTACCTCCTATCATGTGGAGG	EIF2AK2	ENSG00000055332	-0.34079329057507796	[4]	[4,2]	-5	hSpCas9	positive selection	3720031
37146929	37146952	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.3406703874903736	[4]	[5,4]	8	hSpCas9	positive selection	3828633
37147734	37147757	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.04105020795511988	[7]	[6,5]	0	hSpCas9	positive selection	3828634
37147799	37147822	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACGGGAAGAAGAAATGGCTGG	EIF2AK2	ENSG00000055332	-1.2524945989608007	[5]	[1,1]	-9	hSpCas9	positive selection	3828635
37147687	37147710	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGGACCTCCACATGATAGGAGG	EIF2AK2	ENSG00000055332	0.27117970417666	[4]	[4,4]	7	hSpCas9	positive selection	3828636
37141645	37141668	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCAGAAGGATTATCCATGGGG	EIF2AK2	ENSG00000055332	0.15763464002004213	[5]	[5,4]	3	hSpCas9	positive selection	3828637
37147682	37147705	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTACCTCCTATCATGTGGAGG	EIF2AK2	ENSG00000055332	0.1418090792928187	[5]	[5,4]	3	hSpCas9	positive selection	3828638
37146868	37146891	2	+	26780180	A375	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.454028806095426	[]	[]	1	hSpCas9	negative selection	3936038
37141658	37141681	2	-	26780180	A375	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.884900139348838	[]	[]	4	hSpCas9	negative selection	3936039
37146861	37146884	2	-	26780180	A375	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.441156075197733	[]	[]	1	hSpCas9	negative selection	3936040
37147679	37147702	2	+	26780180	A375	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	1.14776545682512	[]	[]	6	hSpCas9	negative selection	3936041
37147743	37147766	2	-	26780180	A375	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	1.3176834191529	[]	[]	7	hSpCas9	negative selection	3936042
37141634	37141657	2	-	26780180	A375	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.319400952523538	[]	[]	0	hSpCas9	negative selection	3936043
37146868	37146891	2	+	26780180	HT29	viability (GeCKOv2 library)	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	1.2905884099452	[]	[]	6	hSpCas9	negative selection	4044004
37141658	37141681	2	-	26780180	HT29	viability (GeCKOv2 library)	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	1.25101667418138	[]	[]	6	hSpCas9	negative selection	4044005
37146861	37146884	2	-	26780180	HT29	viability (GeCKOv2 library)	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	1.27264506557132	[]	[]	6	hSpCas9	negative selection	4044006
37147679	37147702	2	+	26780180	HT29	viability (GeCKOv2 library)	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	0.373423938956225	[]	[]	1	hSpCas9	negative selection	4044007
37147743	37147766	2	-	26780180	HT29	viability (GeCKOv2 library)	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	1.74148352846464	[]	[]	8	hSpCas9	negative selection	4044008
37141634	37141657	2	-	26780180	HT29	viability (GeCKOv2 library)	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.0689860384453185	[]	[]	0	hSpCas9	negative selection	4044009
37146868	37146891	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.029351829230953738	[4]	[2,2]	0	hSpCas9	positive selection	4134185
37146861	37146884	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.025364817292910825	[3]	[2,2]	0	hSpCas9	positive selection	4134186
37147743	37147766	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	0.11259823742995365	[3]	[2,2]	3	hSpCas9	positive selection	4134187
37146868	37146891	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.12721033689568884	[4]	[4,3,0,0]	-2	hSpCas9	positive selection	4198207
37146861	37146884	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.38727940091786195	[3]	[1,2,3,0]	3	hSpCas9	positive selection	4198208
37147743	37147766	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	0.17258753432499158	[4]	[1,4,1,0]	1	hSpCas9	positive selection	4198209
37147743	37147766	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.08940051778724872	[2]	[2,1]	-2	hSpCas9	positive selection	4268415
37141634	37141657	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.47455260377535907	[4]	[4,4]	8	hSpCas9	positive selection	4268416
37141658	37141681	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	-0.21595006683343293	[2]	[2,0]	-4	hSpCas9	positive selection	4268417
37146868	37146891	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.19211540517142323	[1]	[1,0]	-4	hSpCas9	positive selection	4332681
37147679	37147702	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	0.2237191359453795	[4]	[3,3]	4	hSpCas9	positive selection	4332682
37146861	37146884	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.27290366851917536	[2]	[3,2]	5	hSpCas9	positive selection	4332683
37138548	37138570	2	+	27760321	OCIAML3	viability	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.24551380383102117	[139,105]	[80,154]	3	hSpCas9	negative selection	4397121
37139617	37139639	2	+	27760321	OCIAML3	viability	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	-0.03573724305594006	[356,289]	[248,240]	0	hSpCas9	negative selection	4397122
37141569	37141591	2	-	27760321	OCIAML3	viability	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	0.36598292139666516	[577,456]	[381,695]	4	hSpCas9	negative selection	4397123
37141671	37141693	2	+	27760321	OCIAML3	viability	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-1.9954748271112157	[3,5]	[0,0]	-9	hSpCas9	negative selection	4397124
37136990	37137012	2	-	27760321	OCIAML3	viability	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-0.7476500826056873	[79,40]	[30,22]	-6	hSpCas9	negative selection	4397125
37138548	37138570	2	+	27760321	OCIAML2	viability	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.9734173445550611	[139,105]	[160,236]	9	hSpCas9	negative selection	4480584
37139617	37139639	2	+	27760321	OCIAML2	viability	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	0.33593774430344037	[356,289]	[262,414]	4	hSpCas9	negative selection	4480585
37141569	37141591	2	-	27760321	OCIAML2	viability	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-0.14025805269905636	[577,456]	[414,327]	-2	hSpCas9	negative selection	4480586
37141671	37141693	2	+	27760321	OCIAML2	viability	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-2.0442201923762644	[3,5]	[0,0]	-9	hSpCas9	negative selection	4480587
37136990	37137012	2	-	27760321	OCIAML2	viability	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	1.0770123945189416	[79,40]	[58,155]	9	hSpCas9	negative selection	4480588
37138548	37138570	2	+	27760321	MV411	viability	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	-1.009051246977599	[139,105]	[45,30]	-6	hSpCas9	negative selection	4564047
37139617	37139639	2	+	27760321	MV411	viability	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	-0.20170887226580891	[356,289]	[9,446]	-1	hSpCas9	negative selection	4564048
37141569	37141591	2	-	27760321	MV411	viability	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-0.29050221603514126	[577,456]	[99,543]	-2	hSpCas9	negative selection	4564049
37141671	37141693	2	+	27760321	MV411	viability	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-1.7503962581965338	[3,5]	[0,0]	-8	hSpCas9	negative selection	4564050
37136990	37137012	2	-	27760321	MV411	viability	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	0.9727953143236494	[79,40]	[4,183]	7	hSpCas9	negative selection	4564051
37138548	37138570	2	+	27760321	HL60	viability	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	-0.8523013505871668	[139,105]	[61,47]	-7	hSpCas9	negative selection	4647510
37139617	37139639	2	+	27760321	HL60	viability	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	-0.4921807737026215	[356,289]	[199,172]	-5	hSpCas9	negative selection	4647511
37141569	37141591	2	-	27760321	HL60	viability	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	0.5185473196929415	[577,456]	[609,592]	6	hSpCas9	negative selection	4647512
37141671	37141693	2	+	27760321	HL60	viability	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-2.0582664199906704	[3,5]	[0,0]	-9	hSpCas9	negative selection	4647513
37136990	37137012	2	-	27760321	HL60	viability	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-0.1532718135344706	[79,40]	[56,28]	-2	hSpCas9	negative selection	4647514
37138548	37138570	2	+	27760321	HT1080	viability	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	2.1048844569668814	[105,82]	[192,127]	9	hSpCas9	negative selection	4730973
37139617	37139639	2	+	27760321	HT1080	viability	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	1.3032873397056934	[289,226]	[352,145]	7	hSpCas9	negative selection	4730974
37141569	37141591	2	-	27760321	HT1080	viability	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-7.341150053096069	[456,356]	[0,0]	-9	hSpCas9	negative selection	4730975
37141671	37141693	2	+	27760321	HT1080	viability	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	1.8911411959891673	[5,4]	[0,15]	8	hSpCas9	negative selection	4730976
37136990	37137012	2	-	27760321	HT1080	viability	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	0.36834914210847813	[40,31]	[34,0]	2	hSpCas9	negative selection	4730977
37138548	37138570	2	+	27760321	HT29	viability after 7 days	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.3921255658840399	[105,82]	[276,154,65]	6	hSpCas9	negative selection	4814436
37139617	37139639	2	+	27760321	HT29	viability after 7 days	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	0.6326836289744806	[289,226]	[628,555,380]	8	hSpCas9	negative selection	4814437
37141569	37141591	2	-	27760321	HT29	viability after 7 days	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	0.34312163039992855	[456,356]	[660,502,820]	5	hSpCas9	negative selection	4814438
37141671	37141693	2	+	27760321	HT29	viability after 7 days	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-2.827137491385625	[5,4]	[0,0,0]	-9	hSpCas9	negative selection	4814439
37136990	37137012	2	-	27760321	HT29	viability after 7 days	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-0.035628936445302184	[40,31]	[58,28,50]	0	hSpCas9	negative selection	4814440
37138548	37138570	2	+	27760321	HT29	viability after 25 days	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.45391598420054646	[105,82]	[149,106,190]	5	hSpCas9	negative selection	4897899
37139617	37139639	2	+	27760321	HT29	viability after 25 days	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	1.0567965055022415	[289,226]	[532,469,871]	9	hSpCas9	negative selection	4897900
37141569	37141591	2	-	27760321	HT29	viability after 25 days	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	0.09550397878808992	[456,356]	[486,427,584]	0	hSpCas9	negative selection	4897901
37141671	37141693	2	+	27760321	HT29	viability after 25 days	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-1.1736941835918122	[5,4]	[5,0,0]	-7	hSpCas9	negative selection	4897902
37136990	37137012	2	-	27760321	HT29	viability after 25 days	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-0.2604621878950386	[40,31]	[18,80,1]	-3	hSpCas9	negative selection	4897903
37138548	37138570	2	+	27760321	HT29	viability after 22 days	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.5640350158704899	[105,82]	[166,100,216]	6	hSpCas9	negative selection	4981362
37139617	37139639	2	+	27760321	HT29	viability after 22 days	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	0.48529559749761175	[289,226]	[471,443,336]	5	hSpCas9	negative selection	4981363
37141569	37141591	2	-	27760321	HT29	viability after 22 days	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-0.3776182202250503	[456,356]	[382,335,366]	-4	hSpCas9	negative selection	4981364
37141671	37141693	2	+	27760321	HT29	viability after 22 days	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	1.6430216333931114	[5,4]	[46,0,10]	9	hSpCas9	negative selection	4981365
37136990	37137012	2	-	27760321	HT29	viability after 22 days	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-1.165944599303069	[40,31]	[28,22,3]	-7	hSpCas9	negative selection	4981366
37138548	37138570	2	+	27760321	HT29	viability after 19 days	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	1.2462059506300913	[105,82]	[233,228,301]	9	hSpCas9	negative selection	5064825
37139617	37139639	2	+	27760321	HT29	viability after 19 days	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	0.6244907099943656	[289,226]	[434,578,354]	6	hSpCas9	negative selection	5064826
37141569	37141591	2	-	27760321	HT29	viability after 19 days	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-0.518217203029607	[456,356]	[396,329,257]	-4	hSpCas9	negative selection	5064827
37141671	37141693	2	+	27760321	HT29	viability after 19 days	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-0.8602866933279918	[5,4]	[0,0,7]	-6	hSpCas9	negative selection	5064828
37136990	37137012	2	-	27760321	HT29	viability after 19 days	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-1.518329349023273	[40,31]	[40,4,0]	-7	hSpCas9	negative selection	5064829
37138548	37138570	2	+	27760321	HT29	viability after 16 days	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.45102478792411027	[105,82]	[159,33,243]	5	hSpCas9	negative selection	5148288
37139617	37139639	2	+	27760321	HT29	viability after 16 days	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	0.4854429205121307	[289,226]	[528,311,387]	5	hSpCas9	negative selection	5148289
37141569	37141591	2	-	27760321	HT29	viability after 16 days	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-0.07175669965243342	[456,356]	[371,432,488]	-1	hSpCas9	negative selection	5148290
37141671	37141693	2	+	27760321	HT29	viability after 16 days	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-2.6271736296980093	[5,4]	[0,0,0]	-8	hSpCas9	negative selection	5148291
37136990	37137012	2	-	27760321	HT29	viability after 16 days	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-0.49339974555309407	[40,31]	[59,26,2]	-5	hSpCas9	negative selection	5148292
37138548	37138570	2	+	27760321	HT29	viability after 13 days	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.23715616782093352	[105,82]	[141,138,107]	3	hSpCas9	negative selection	5231751
37139617	37139639	2	+	27760321	HT29	viability after 13 days	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	0.4098604489042361	[289,226]	[491,420,288]	5	hSpCas9	negative selection	5231752
37141569	37141591	2	-	27760321	HT29	viability after 13 days	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	0.03879434109365407	[456,356]	[554,330,563]	0	hSpCas9	negative selection	5231753
37141671	37141693	2	+	27760321	HT29	viability after 13 days	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-1.239241750686741	[5,4]	[1,0,4]	-8	hSpCas9	negative selection	5231754
37136990	37137012	2	-	27760321	HT29	viability after 13 days	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	0.3285603507462058	[40,31]	[60,70,28]	4	hSpCas9	negative selection	5231755
37138548	37138570	2	+	27760321	HT29	viability after 10 days	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	1.3213195692971726	[105,82]	[469,142,267]	9	hSpCas9	negative selection	5315214
37139617	37139639	2	+	27760321	HT29	viability after 10 days	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	0.26565678273938875	[289,226]	[255,523,387]	3	hSpCas9	negative selection	5315215
37141569	37141591	2	-	27760321	HT29	viability after 10 days	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	-0.2602703515806758	[456,356]	[493,275,496]	-3	hSpCas9	negative selection	5315216
37141671	37141693	2	+	27760321	HT29	viability after 10 days	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-2.785472336302491	[5,4]	[0,0,0]	-9	hSpCas9	negative selection	5315217
37136990	37137012	2	-	27760321	HT29	viability after 10 days	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	-0.43735872029775713	[40,31]	[36,32,30]	-5	hSpCas9	negative selection	5315218
37138548	37138570	2	+	27760321	MOLM13	viability	GTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.554456994400985	[139,105]	[119,84]	4	hSpCas9	negative selection	5398677
37139617	37139639	2	+	27760321	MOLM13	viability	AAGGCAATACGTACCACTGAGG	EIF2AK2	ENSG00000055332	-0.12160850683614999	[356,289]	[275,73]	-1	hSpCas9	negative selection	5398678
37141569	37141591	2	-	27760321	MOLM13	viability	TATGAACAGTGTGCATCGGGGG	EIF2AK2	ENSG00000055332	0.20228436981344355	[577,456]	[544,153]	1	hSpCas9	negative selection	5398679
37141671	37141693	2	+	27760321	MOLM13	viability	TCGTTGTTGTCAATAATAAAGG	EIF2AK2	ENSG00000055332	-1.5243394453689385	[3,5]	[0,0]	-7	hSpCas9	negative selection	5398680
37136990	37137012	2	-	27760321	MOLM13	viability	CTCAGAAATAATCAAAGGAAGG	EIF2AK2	ENSG00000055332	0.48452205898666856	[79,40]	[10,76]	3	hSpCas9	negative selection	5398681
37156511	37156534	2	-	27661255	K562	viability	GGCCTGAAATACTCATAGACTGG	EIF2AK2	ENSG00000055332	0.5369943616868813	[322,451]	[433,456]	9	dCas9-KRAB	negative selection	5476869
37156564	37156587	2	-	27661255	K562	viability	GGGTCTAGTGGAAGACGAATAGG	EIF2AK2	ENSG00000055332	-0.0009537501221300593	[1317,1250]	[1156,914]	0	dCas9-KRAB	negative selection	5476870
37156898	37156921	2	-	27661255	K562	viability	GGCGGCGGCGCAGGTGAGCAGGG	EIF2AK2	ENSG00000055332	-0.0657111861773389	[689,628]	[548,465]	-3	dCas9-KRAB	negative selection	5476871
37147743	37147766	2	-	27260156	BXPC3	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.40119871683169367	[394]	[272,274,336,378]	-7	hSpCas9	negative selection	5540875
37141634	37141657	2	-	27260156	BXPC3	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.2452060370393634	[1198]	[1353,1440,1395,1795]	5	hSpCas9	negative selection	5540876
37141658	37141681	2	-	27260156	BXPC3	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.2745662882363117	[247]	[225,298,367,378]	6	hSpCas9	negative selection	5540877
37146868	37146891	2	+	27260156	BXPC3	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.2758565773531445	[111]	[96,83,118,85]	-6	hSpCas9	negative selection	5605141
37147679	37147702	2	+	27260156	BXPC3	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.12294058098820537	[1080]	[796,1022,1225,1141]	-3	hSpCas9	negative selection	5605142
37146861	37146884	2	-	27260156	BXPC3	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.01165516025311393	[442]	[386,521,395,542]	0	hSpCas9	negative selection	5605143
37147743	37147766	2	-	27260156	A673	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.5920276739541934	[394]	[342,312,297,306]	-8	hSpCas9	negative selection	5662126
37141634	37141657	2	-	27260156	A673	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.21659077558884188	[1198]	[1721,1645,1634,1692]	5	hSpCas9	negative selection	5662127
37141658	37141681	2	-	27260156	A673	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.19481586978393717	[247]	[373,374,307,306]	4	hSpCas9	negative selection	5662128
37146868	37146891	2	+	27260156	A673	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.3026846184883407	[111]	[107,103,141,79]	-6	hSpCas9	negative selection	5726392
37147679	37147702	2	+	27260156	A673	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.06545491952532845	[1080]	[1176,1200,1304,1270]	-2	hSpCas9	negative selection	5726393
37146861	37146884	2	-	27260156	A673	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.004149247572222431	[442]	[524,561,484,560]	0	hSpCas9	negative selection	5726394
37147743	37147766	2	-	27260156	A375	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.021857864380472658	[394]	[529,483,503,318]	0	hSpCas9	negative selection	5783377
37141634	37141657	2	-	27260156	A375	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.3017491405893973	[1198]	[1225,1572,1031,809]	-4	hSpCas9	negative selection	5783378
37141658	37141681	2	-	27260156	A375	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5291430040975471	[247]	[303,614,415,367]	7	hSpCas9	negative selection	5783379
37146868	37146891	2	+	27260156	A375	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.051473041899715355	[111]	[206,144,59,131]	0	hSpCas9	negative selection	5847643
37147679	37147702	2	+	27260156	A375	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2658524725314112	[1080]	[1085,1104,1154,878]	-4	hSpCas9	negative selection	5847644
37146861	37146884	2	-	27260156	A375	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.07486769819919062	[442]	[517,777,479,445]	1	hSpCas9	negative selection	5847645
37147743	37147766	2	-	27260156	COLO741	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.20300591431969195	[394]	[530,435,360]	-4	hSpCas9	negative selection	5904628
37141634	37141657	2	-	27260156	COLO741	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.0952893454386805	[1198]	[1633,1567,1698]	2	hSpCas9	negative selection	5904629
37141658	37141681	2	-	27260156	COLO741	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5034241876561473	[247]	[433,443,465]	8	hSpCas9	negative selection	5904630
37146868	37146891	2	+	27260156	COLO741	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.26021120252406105	[111]	[178,76,107]	-5	hSpCas9	negative selection	5968894
37147679	37147702	2	+	27260156	COLO741	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.0882335515980559	[1080]	[1576,1238,1115]	-2	hSpCas9	negative selection	5968895
37146861	37146884	2	-	27260156	COLO741	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.25754181516854985	[442]	[498,441,479]	-5	hSpCas9	negative selection	5968896
37147743	37147766	2	-	27260156	CAL120	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.13801325987157553	[394]	[482,507,355]	-2	hSpCas9	negative selection	6025879
37141634	37141657	2	-	27260156	CAL120	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.28934589604271976	[1198]	[2096,1503,1907]	4	hSpCas9	negative selection	6025880
37141658	37141681	2	-	27260156	CAL120	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.6873483397942681	[247]	[462,717,307]	8	hSpCas9	negative selection	6025881
37146868	37146891	2	+	27260156	CAL120	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.29999137343240534	[111]	[13,194,279]	4	hSpCas9	negative selection	6090145
37147679	37147702	2	+	27260156	CAL120	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2499419716992154	[1080]	[1115,983,1287]	-4	hSpCas9	negative selection	6090146
37146861	37146884	2	-	27260156	CAL120	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.6690148230178056	[442]	[707,1086,809]	8	hSpCas9	negative selection	6090147
37147743	37147766	2	-	27260156	CADOES1	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.049295763083950894	[394]	[487,308,183,441]	-1	hSpCas9	negative selection	6147130
37141634	37141657	2	-	27260156	CADOES1	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.026710658857682867	[1198]	[1160,952,1278,1150]	0	hSpCas9	negative selection	6147131
37141658	37141681	2	-	27260156	CADOES1	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.6122471106260654	[247]	[352,573,254,223]	8	hSpCas9	negative selection	6147132
37146868	37146891	2	+	27260156	CADOES1	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.11727169433955487	[111]	[50,155,90,85]	-2	hSpCas9	negative selection	6211396
37147679	37147702	2	+	27260156	CADOES1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2508174290595382	[1080]	[807,807,913,849]	-4	hSpCas9	negative selection	6211397
37146861	37146884	2	-	27260156	CADOES1	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.2314444313763801	[442]	[343,793,412,380]	4	hSpCas9	negative selection	6211398
37147743	37147766	2	-	27260156	EWS502	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.2808488564466179	[394]	[268,355,332,432]	-5	hSpCas9	negative selection	6268381
37141634	37141657	2	-	27260156	EWS502	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.31869345919535497	[1198]	[1556,1265,1776,1760]	5	hSpCas9	negative selection	6268382
37141658	37141681	2	-	27260156	EWS502	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.9040155299333787	[247]	[669,426,423,417]	9	hSpCas9	negative selection	6268383
37146868	37146891	2	+	27260156	EWS502	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.34370618493767147	[111]	[47,157,31,140]	-5	hSpCas9	negative selection	6332647
37147679	37147702	2	+	27260156	EWS502	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.13746602094994587	[1080]	[1009,1027,964,1168]	-2	hSpCas9	negative selection	6332648
37146861	37146884	2	-	27260156	EWS502	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.37773580629295644	[442]	[557,433,626,847]	6	hSpCas9	negative selection	6332649
37147743	37147766	2	-	27260156	EW8	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.5160510430211716	[394]	[241,274,188,196]	-7	hSpCas9	negative selection	6389632
37141634	37141657	2	-	27260156	EW8	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.2098382285372089	[1198]	[1230,1053,820,1447]	4	hSpCas9	negative selection	6389633
37141658	37141681	2	-	27260156	EW8	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.4189067109477984	[247]	[296,184,277,314]	7	hSpCas9	negative selection	6389634
37146868	37146891	2	+	27260156	EW8	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.785255967857579	[111]	[201,52,165,206]	9	hSpCas9	negative selection	6453898
37147679	37147702	2	+	27260156	EW8	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2093587730025589	[1080]	[703,1029,611,702]	-4	hSpCas9	negative selection	6453899
37146861	37146884	2	-	27260156	EW8	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.2508592768600482	[442]	[630,416,339,356]	4	hSpCas9	negative selection	6453900
37147743	37147766	2	-	27260156	CORL105	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.4643413370554242	[394]	[384,307,360,292]	-7	hSpCas9	negative selection	6510883
37141634	37141657	2	-	27260156	CORL105	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.0452527869177799	[1198]	[1291,1476,1395,1276]	-1	hSpCas9	negative selection	6510884
37141658	37141681	2	-	27260156	CORL105	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.6521480805504578	[247]	[375,409,596,461]	9	hSpCas9	negative selection	6510885
37146868	37146891	2	+	27260156	CORL105	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.24721160704841116	[111]	[55,177,253,145]	4	hSpCas9	negative selection	6575149
37147679	37147702	2	+	27260156	CORL105	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.5473150298841573	[1080]	[822,709,944,998]	-7	hSpCas9	negative selection	6575150
37146861	37146884	2	-	27260156	CORL105	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.008882327421608688	[442]	[642,477,537,435]	0	hSpCas9	negative selection	6575151
37147743	37147766	2	-	27260156	HS294T	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	0.4732308587283616	[394]	[447,153,103,101]	6	hSpCas9	negative selection	6632134
37141634	37141657	2	-	27260156	HS294T	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.12603062022674205	[1198]	[380,273,448,638]	-2	hSpCas9	negative selection	6632135
37141658	37141681	2	-	27260156	HS294T	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.9513667518782859	[247]	[169,107,97,405]	9	hSpCas9	negative selection	6632136
37146868	37146891	2	+	27260156	HS294T	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.899084079981638	[111]	[36,48,51,211]	9	hSpCas9	negative selection	6696400
37147679	37147702	2	+	27260156	HS294T	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2963248066223665	[1080]	[219,252,356,585]	-4	hSpCas9	negative selection	6696401
37146861	37146884	2	-	27260156	HS294T	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.08317845386086005	[442]	[182,142,135,186]	-1	hSpCas9	negative selection	6696402
37147743	37147766	2	-	27260156	HCC44	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.08656748320721236	[394]	[351,342,568,444]	-1	hSpCas9	negative selection	6753385
37141634	37141657	2	-	27260156	HCC44	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.3641721385168213	[1198]	[2169,1329,2261,1403]	6	hSpCas9	negative selection	6753386
37141658	37141681	2	-	27260156	HCC44	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.7061653393020635	[247]	[448,448,604,352]	9	hSpCas9	negative selection	6753387
37146868	37146891	2	+	27260156	HCC44	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.03008016540353209	[111]	[79,190,159,58]	0	hSpCas9	negative selection	6817651
37147679	37147702	2	+	27260156	HCC44	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.1544773711166847	[1080]	[1136,967,1080,1213]	-3	hSpCas9	negative selection	6817652
37146861	37146884	2	-	27260156	HCC44	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.2339227150697012	[442]	[791,501,684,425]	4	hSpCas9	negative selection	6817653
37147743	37147766	2	-	27260156	G402	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.6982892196157391	[394]	[437,392,106,275]	-7	hSpCas9	negative selection	6874636
37141634	37141657	2	-	27260156	G402	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.06064559061476715	[1198]	[847,1868,2317,1009]	0	hSpCas9	negative selection	6874637
37141658	37141681	2	-	27260156	G402	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.542787194132432	[247]	[321,449,637,339]	6	hSpCas9	negative selection	6874638
37146868	37146891	2	+	27260156	G402	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.39335411778582996	[111]	[47,134,211,294]	5	hSpCas9	negative selection	6938902
37147679	37147702	2	+	27260156	G402	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-1.0140016938568799	[1080]	[822,547,339,904]	-8	hSpCas9	negative selection	6938903
37146861	37146884	2	-	27260156	G402	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.11918242318717154	[442]	[1061,617,371,374]	1	hSpCas9	negative selection	6938904
37147743	37147766	2	-	27260156	L33	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.3434490031867807	[394]	[328,134,149,346]	-7	hSpCas9	negative selection	6995887
37141634	37141657	2	-	27260156	L33	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.17195285499065904	[1198]	[1286,494,800,1631]	4	hSpCas9	negative selection	6995888
37141658	37141681	2	-	27260156	L33	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	-0.0026458773976175687	[247]	[210,126,150,229]	0	hSpCas9	negative selection	6995889
37146868	37146891	2	+	27260156	L33	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.012401288354024764	[111]	[112,24,124,71]	0	hSpCas9	negative selection	7060153
37147679	37147702	2	+	27260156	L33	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.012493080778822163	[1080]	[963,410,661,1266]	0	hSpCas9	negative selection	7060154
37146861	37146884	2	-	27260156	L33	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.07492179234501574	[442]	[432,184,268,369]	-2	hSpCas9	negative selection	7060155
37147743	37147766	2	-	27260156	K562	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.239123169468273	[394]	[266,509,305,131]	-3	hSpCas9	negative selection	7117138
37141634	37141657	2	-	27260156	K562	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.048399180248418716	[1198]	[1403,978,1138,660]	0	hSpCas9	negative selection	7117139
37141658	37141681	2	-	27260156	K562	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	1.0870348975300694	[247]	[521,517,553,300]	9	hSpCas9	negative selection	7117140
37146868	37146891	2	+	27260156	K562	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.19161805581780977	[111]	[246,162,55,12]	2	hSpCas9	negative selection	7181404
37147679	37147702	2	+	27260156	K562	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.1760158035861854	[1080]	[1336,852,638,629]	-2	hSpCas9	negative selection	7181405
37146861	37146884	2	-	27260156	K562	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.08103778118833757	[442]	[369,761,259,297]	1	hSpCas9	negative selection	7181406
37147743	37147766	2	-	27260156	HT29	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.19339664693493097	[394]	[416,493,335,433]	-4	hSpCas9	negative selection	7238389
37141634	37141657	2	-	27260156	HT29	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.07123940221583491	[1198]	[1421,1774,1599,1351]	1	hSpCas9	negative selection	7238390
37141658	37141681	2	-	27260156	HT29	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5984944292692641	[247]	[539,619,423,280]	9	hSpCas9	negative selection	7238391
37146868	37146891	2	+	27260156	HT29	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.3681351384525835	[111]	[132,260,165,148]	7	hSpCas9	negative selection	7302655
37147679	37147702	2	+	27260156	HT29	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	0.066851679854254	[1080]	[1325,1623,1285,1287]	1	hSpCas9	negative selection	7302656
37146861	37146884	2	-	27260156	HT29	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.012745875304552776	[442]	[475,742,519,419]	0	hSpCas9	negative selection	7302657
37147743	37147766	2	-	27260156	MHHES1	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.30178591033471186	[394]	[263,375,381,394]	-5	hSpCas9	negative selection	7359640
37141634	37141657	2	-	27260156	MHHES1	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.30897854220914756	[1198]	[2104,1696,1551,1413]	5	hSpCas9	negative selection	7359641
37141658	37141681	2	-	27260156	MHHES1	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5563728335966989	[247]	[488,345,505,317]	8	hSpCas9	negative selection	7359642
37146868	37146891	2	+	27260156	MHHES1	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.03206837491862302	[111]	[156,184,113,77]	0	hSpCas9	negative selection	7423906
37147679	37147702	2	+	27260156	MHHES1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.1439039015261383	[1080]	[1293,1165,974,999]	-3	hSpCas9	negative selection	7423907
37146861	37146884	2	-	27260156	MHHES1	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.22471366729825748	[442]	[590,630,650,476]	4	hSpCas9	negative selection	7423908
37147743	37147766	2	-	27260156	MEWO	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.741328754467808	[394]	[240,218,206]	-9	hSpCas9	negative selection	7480891
37141634	37141657	2	-	27260156	MEWO	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.19098966697446307	[1198]	[1439,1108,1323]	4	hSpCas9	negative selection	7480892
37141658	37141681	2	-	27260156	MEWO	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.7092625507535559	[247]	[276,403,436]	9	hSpCas9	negative selection	7480893
37146868	37146891	2	+	27260156	MEWO	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.7361431823645987	[111]	[54,97,33]	-9	hSpCas9	negative selection	7545157
37147679	37147702	2	+	27260156	MEWO	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.17212116443963477	[1080]	[906,985,800]	-4	hSpCas9	negative selection	7545158
37146861	37146884	2	-	27260156	MEWO	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.05944529054167662	[442]	[592,386,346]	1	hSpCas9	negative selection	7545159
37147743	37147766	2	-	27260156	LNCAPCLONEFGC	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.20435587613671385	[394]	[226,301,443,290]	-3	hSpCas9	negative selection	7602142
37141634	37141657	2	-	27260156	LNCAPCLONEFGC	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.14660097748491552	[1198]	[1243,1001,1560,1066]	2	hSpCas9	negative selection	7602143
37141658	37141681	2	-	27260156	LNCAPCLONEFGC	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.4655433344384058	[247]	[225,338,354,326]	7	hSpCas9	negative selection	7602144
37146868	37146891	2	+	27260156	LNCAPCLONEFGC	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.7820432384413225	[111]	[166,182,131,208]	9	hSpCas9	negative selection	7666408
37147679	37147702	2	+	27260156	LNCAPCLONEFGC	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.3814209520177215	[1080]	[624,767,880,752]	-5	hSpCas9	negative selection	7666409
37146861	37146884	2	-	27260156	LNCAPCLONEFGC	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.33131878999461417	[442]	[514,568,384,527]	5	hSpCas9	negative selection	7666410
37147743	37147766	2	-	27260156	PANC0327	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.5003246503961281	[394]	[319,248,261,166]	-6	hSpCas9	negative selection	7723393
37141634	37141657	2	-	27260156	PANC0327	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.2918533382088466	[1198]	[1423,1173,1413,1229]	4	hSpCas9	negative selection	7723394
37141658	37141681	2	-	27260156	PANC0327	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.42839887997933895	[247]	[371,227,378,221]	6	hSpCas9	negative selection	7723395
37146868	37146891	2	+	27260156	PANC0327	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.40094090831148943	[111]	[106,166,202,41]	6	hSpCas9	negative selection	7787659
37147679	37147702	2	+	27260156	PANC0327	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.49588836305555717	[1080]	[662,510,721,847]	-6	hSpCas9	negative selection	7787660
37146861	37146884	2	-	27260156	PANC0327	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.07612118212973921	[442]	[285,394,342,458]	-1	hSpCas9	negative selection	7787661
37147743	37147766	2	-	27260156	NCIH2009	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.09559573165562302	[394]	[430,334,768]	-1	hSpCas9	negative selection	7844644
37141634	37141657	2	-	27260156	NCIH2009	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.1776919131987995	[1198]	[1731,1330,1429]	-2	hSpCas9	negative selection	7844645
37141658	37141681	2	-	27260156	NCIH2009	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.2932670663523005	[247]	[487,402,394]	4	hSpCas9	negative selection	7844646
37146868	37146891	2	+	27260156	NCIH2009	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.13286021632906841	[111]	[289,107,140]	1	hSpCas9	negative selection	7908910
37147679	37147702	2	+	27260156	NCIH2009	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.6220510202846193	[1080]	[1201,977,805]	-7	hSpCas9	negative selection	7908911
37146861	37146884	2	-	27260156	NCIH2009	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.053430758347897275	[442]	[729,689,392]	0	hSpCas9	negative selection	7908912
37147743	37147766	2	-	27260156	NCIH1373	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	0.20536862694726268	[394]	[487,304,511,201]	2	hSpCas9	negative selection	7965895
37141634	37141657	2	-	27260156	NCIH1373	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.4286289252369969	[1198]	[1443,770,918,248]	-4	hSpCas9	negative selection	7965896
37141658	37141681	2	-	27260156	NCIH1373	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.9417849457629264	[247]	[212,746,663,111]	8	hSpCas9	negative selection	7965897
37146868	37146891	2	+	27260156	NCIH1373	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.1440949096753701	[111]	[124,45,158,34]	-1	hSpCas9	negative selection	8030161
37147679	37147702	2	+	27260156	NCIH1373	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.994935817766341	[1080]	[761,712,344,164]	-7	hSpCas9	negative selection	8030162
37146861	37146884	2	-	27260156	NCIH1373	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.13303633863892905	[442]	[553,313,345,167]	-1	hSpCas9	negative selection	8030163
37147743	37147766	2	-	27260156	PATU8902	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.22069568535203204	[394]	[516,294,250,932]	-2	hSpCas9	negative selection	8087146
37141634	37141657	2	-	27260156	PATU8902	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.21782342528464094	[1198]	[2074,2274,1359,2226]	2	hSpCas9	negative selection	8087147
37141658	37141681	2	-	27260156	PATU8902	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.8006058432751366	[247]	[632,555,462,809]	8	hSpCas9	negative selection	8087148
37146868	37146891	2	+	27260156	PATU8902	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.8785614693796544	[111]	[440,455,72,220]	8	hSpCas9	negative selection	8151412
37147679	37147702	2	+	27260156	PATU8902	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.74510235501723	[1080]	[601,1021,452,1727]	-6	hSpCas9	negative selection	8151413
37146861	37146884	2	-	27260156	PATU8902	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.22365289178157205	[442]	[630,1148,253,998]	2	hSpCas9	negative selection	8151414
37147743	37147766	2	-	27260156	PANC1	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.195480986857132	[394]	[257,447,298,219]	-3	hSpCas9	negative selection	8208397
37141634	37141657	2	-	27260156	PANC1	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.1982150930338462	[1198]	[1291,1412,1340,774]	3	hSpCas9	negative selection	8208398
37141658	37141681	2	-	27260156	PANC1	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.46434697615633225	[247]	[293,362,257,272]	7	hSpCas9	negative selection	8208399
37146868	37146891	2	+	27260156	PANC1	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.11531248379679004	[111]	[57,178,87,105]	1	hSpCas9	negative selection	8272663
37147679	37147702	2	+	27260156	PANC1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2952193039524694	[1080]	[719,846,848,637]	-5	hSpCas9	negative selection	8272664
37146861	37146884	2	-	27260156	PANC1	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.3064797167598739	[442]	[509,433,419,496]	5	hSpCas9	negative selection	8272665
37147743	37147766	2	-	27260156	PANC0813	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.37502354220113193	[394]	[397,375,388,275]	-5	hSpCas9	negative selection	8329648
37141634	37141657	2	-	27260156	PANC0813	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.09584997802694883	[1198]	[1503,1627,1666,1234]	1	hSpCas9	negative selection	8329649
37141658	37141681	2	-	27260156	PANC0813	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.20510218716553397	[247]	[394,304,310,336]	3	hSpCas9	negative selection	8329650
37146868	37146891	2	+	27260156	PANC0813	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.15271366042351908	[111]	[165,138,108,170]	2	hSpCas9	negative selection	8393914
37147679	37147702	2	+	27260156	PANC0813	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.36098167295952055	[1080]	[906,1256,937,850]	-5	hSpCas9	negative selection	8393915
37146861	37146884	2	-	27260156	PANC0813	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.05217876585072391	[442]	[471,483,474,568]	-1	hSpCas9	negative selection	8393916
37147743	37147766	2	-	27260156	RDES	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.23633450038858672	[394]	[272,317,430,570]	-4	hSpCas9	negative selection	8450899
37141634	37141657	2	-	27260156	RDES	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	-0.007212871881322025	[1198]	[1084,1134,1408,2001]	0	hSpCas9	negative selection	8450900
37141658	37141681	2	-	27260156	RDES	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5618866246137091	[247]	[380,316,367,657]	8	hSpCas9	negative selection	8450901
37146868	37146891	2	+	27260156	RDES	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.17918583563387314	[111]	[80,99,125,160]	-3	hSpCas9	negative selection	8515165
37147679	37147702	2	+	27260156	RDES	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.08269490184931394	[1080]	[826,868,1424,1744]	-1	hSpCas9	negative selection	8515166
37146861	37146884	2	-	27260156	RDES	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.34351179244001584	[442]	[489,668,759,689]	5	hSpCas9	negative selection	8515167
37147743	37147766	2	-	27260156	PC3	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.274749488188539	[394]	[214,253,648,329]	-6	hSpCas9	negative selection	8572150
37141634	37141657	2	-	27260156	PC3	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.1902589220046833	[1198]	[1004,1365,2073,1284]	4	hSpCas9	negative selection	8572151
37141658	37141681	2	-	27260156	PC3	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	-0.03481279465052167	[247]	[149,233,344,295]	-1	hSpCas9	negative selection	8572152
37146868	37146891	2	+	27260156	PC3	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.7602392128178952	[111]	[21,100,71,84]	-9	hSpCas9	negative selection	8636416
37147679	37147702	2	+	27260156	PC3	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.188021763506808	[1080]	[765,848,1369,930]	-4	hSpCas9	negative selection	8636417
37146861	37146884	2	-	27260156	PC3	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.3545628818049711	[442]	[196,288,576,450]	-7	hSpCas9	negative selection	8636418
37147743	37147766	2	-	27260156	PATU8988T	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.39166195388691166	[394]	[262,378,343,175]	-6	hSpCas9	negative selection	8693401
37141634	37141657	2	-	27260156	PATU8988T	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.10216380441979478	[1198]	[1153,1181,1537,1076]	1	hSpCas9	negative selection	8693402
37141658	37141681	2	-	27260156	PATU8988T	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.490123766693521	[247]	[617,311,242,157]	7	hSpCas9	negative selection	8693403
37146868	37146891	2	+	27260156	PATU8988T	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.558786002782738	[111]	[127,22,86,48]	-7	hSpCas9	negative selection	8757667
37147679	37147702	2	+	27260156	PATU8988T	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.06883305863371936	[1080]	[783,911,1275,999]	-1	hSpCas9	negative selection	8757668
37146861	37146884	2	-	27260156	PATU8988T	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	-0.055978972464706914	[442]	[501,428,239,485]	-1	hSpCas9	negative selection	8757669
37147743	37147766	2	-	27260156	T47D	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.20786899534404946	[394]	[373,357,483,378]	-4	hSpCas9	negative selection	8814652
37141634	37141657	2	-	27260156	T47D	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.23127907262983438	[1198]	[1612,1552,1793,1601]	5	hSpCas9	negative selection	8814653
37141658	37141681	2	-	27260156	T47D	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.39547240075332013	[247]	[388,326,425,381]	8	hSpCas9	negative selection	8814654
37146868	37146891	2	+	27260156	T47D	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.0381146766174818	[111]	[107,112,137,150]	-1	hSpCas9	negative selection	8878918
37147679	37147702	2	+	27260156	T47D	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.09181267136341553	[1080]	[1274,976,1199,1295]	-2	hSpCas9	negative selection	8878919
37146861	37146884	2	-	27260156	T47D	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.14754247318669278	[442]	[630,609,490,551]	3	hSpCas9	negative selection	8878920
37147743	37147766	2	-	27260156	SU8686	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.28709280576373036	[394]	[289,353,280,360]	-5	hSpCas9	negative selection	8935903
37141634	37141657	2	-	27260156	SU8686	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.24194933040987854	[1198]	[1459,1178,1460,1562]	4	hSpCas9	negative selection	8935904
37141658	37141681	2	-	27260156	SU8686	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.49171920609077513	[247]	[267,328,372,436]	7	hSpCas9	negative selection	8935905
37146868	37146891	2	+	27260156	SU8686	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.22689330057006307	[111]	[109,100,122,32]	-4	hSpCas9	negative selection	9000169
37147679	37147702	2	+	27260156	SU8686	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.2012112364572689	[1080]	[907,730,850,1321]	-4	hSpCas9	negative selection	9000170
37146861	37146884	2	-	27260156	SU8686	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.04979732002054085	[442]	[259,401,648,554]	0	hSpCas9	negative selection	9000171
37147743	37147766	2	-	27260156	SKES1	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.45051932678824286	[394]	[286,310,327,232]	-7	hSpCas9	negative selection	9057154
37141634	37141657	2	-	27260156	SKES1	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.11999573773205952	[1198]	[1449,1199,1215,1325]	2	hSpCas9	negative selection	9057155
37141658	37141681	2	-	27260156	SKES1	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5439629910364931	[247]	[313,365,426,328]	9	hSpCas9	negative selection	9057156
37146868	37146891	2	+	27260156	SKES1	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	0.3083535590414477	[111]	[156,75,117,189]	6	hSpCas9	negative selection	9121420
37147679	37147702	2	+	27260156	SKES1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.046793789425041865	[1080]	[1335,1199,917,800]	-1	hSpCas9	negative selection	9121421
37146861	37146884	2	-	27260156	SKES1	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.18789963015162497	[442]	[494,485,710,330]	4	hSpCas9	negative selection	9121422
37147743	37147766	2	-	27260156	TOV112D	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.2946815866576586	[394]	[315,319,351,300]	-5	hSpCas9	negative selection	9178405
37141634	37141657	2	-	27260156	TOV112D	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.40843800887654935	[1198]	[1497,2154,1337,1513]	7	hSpCas9	negative selection	9178406
37141658	37141681	2	-	27260156	TOV112D	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.6369092518386525	[247]	[369,578,313,328]	9	hSpCas9	negative selection	9178407
37146868	37146891	2	+	27260156	TOV112D	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.4463021921566952	[111]	[19,204,78,50]	-7	hSpCas9	negative selection	9242671
37147679	37147702	2	+	27260156	TOV112D	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	0.30822304225009733	[1080]	[1287,1433,1114,1535]	6	hSpCas9	negative selection	9242672
37146861	37146884	2	-	27260156	TOV112D	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.11934387607286231	[442]	[280,397,531,672]	2	hSpCas9	negative selection	9242673
37147743	37147766	2	-	27260156	TC71	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.6124102639801972	[394]	[251,345,281,224]	-9	hSpCas9	negative selection	9299656
37141634	37141657	2	-	27260156	TC71	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.3024632695978926	[1198]	[1714,1411,1651,1553]	7	hSpCas9	negative selection	9299657
37141658	37141681	2	-	27260156	TC71	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5436162426254807	[247]	[315,414,362,462]	9	hSpCas9	negative selection	9299658
37146868	37146891	2	+	27260156	TC71	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.6746052718409006	[111]	[93,88,67,47]	-9	hSpCas9	negative selection	9363922
37147679	37147702	2	+	27260156	TC71	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.1499488333375527	[1080]	[1102,1047,983,1042]	-4	hSpCas9	negative selection	9363923
37146861	37146884	2	-	27260156	TC71	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.14845111095843838	[442]	[522,468,499,619]	4	hSpCas9	negative selection	9363924
37147743	37147766	2	-	27260156	TC32	viability	TAATACATACCGTCAGAAGCAGG	EIF2AK2	ENSG00000055332	-0.44298867070960307	[394]	[258,211,340,301]	-7	hSpCas9	negative selection	9420907
37141634	37141657	2	-	27260156	TC32	viability	TTATCCATGGGGAATTACATAGG	EIF2AK2	ENSG00000055332	0.2555630251883889	[1198]	[1132,1205,1473,1599]	4	hSpCas9	negative selection	9420908
37141658	37141681	2	-	27260156	TC32	viability	ACAACAACGAATTCTTCAGAAGG	EIF2AK2	ENSG00000055332	0.5799058961969223	[247]	[396,247,432,339]	8	hSpCas9	negative selection	9420909
37146868	37146891	2	+	27260156	TC32	viability	AAGTATCTCAACAGCTAATTTGG	EIF2AK2	ENSG00000055332	-0.32268123968100104	[111]	[113,46,87,93]	-5	hSpCas9	negative selection	9485173
37147679	37147702	2	+	27260156	TC32	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.25194651827313974	[1080]	[823,714,1100,815]	-4	hSpCas9	negative selection	9485174
37146861	37146884	2	-	27260156	TC32	viability	AGCTGTTGAGATACTTAATAAGG	EIF2AK2	ENSG00000055332	0.10315856707322346	[442]	[444,327,723,352]	2	hSpCas9	negative selection	9485175
37109265	37109288	2	-	27869803	HPAFII	viability after 27 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.2702860485249909	[276]	[53,276,NaN]	2	hSpCas9	negative selection	9574904
37114730	37114753	2	-	27869803	HPAFII	viability after 27 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.5652323519798608	[843]	[679,636,NaN]	4	hSpCas9	negative selection	9574905
37120121	37120144	2	+	27869803	HPAFII	viability after 27 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.2594321691535981	[82]	[66,10,NaN]	-2	hSpCas9	negative selection	9574906
37109265	37109288	2	-	27869803	HPAFII	viability after 15 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.18000943863349034	[276]	[218,289,NaN]	-2	hSpCas9	negative selection	9657353
37114730	37114753	2	-	27869803	HPAFII	viability after 15 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.26200041693834164	[843]	[1506,826,NaN]	3	hSpCas9	negative selection	9657354
37120121	37120144	2	+	27869803	HPAFII	viability after 15 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.6123136496830981	[82]	[74,47,NaN]	-6	hSpCas9	negative selection	9657355
37109265	37109288	2	-	27869803	ASPC1	viability after 36 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.5521334056787478	[608]	[252,217,423]	5	hSpCas9	negative selection	9739802
37114730	37114753	2	-	27869803	ASPC1	viability after 36 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	-0.24401275501652608	[1837]	[278,962,385]	-3	hSpCas9	negative selection	9739803
37120121	37120144	2	+	27869803	ASPC1	viability after 36 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.3228667928335587	[527]	[70,366,24]	-3	hSpCas9	negative selection	9739804
37109265	37109288	2	-	27869803	PATU8988S	viability after 35 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.6058321024114702	[490]	[277,323,NaN]	6	hSpCas9	negative selection	9822251
37114730	37114753	2	-	27869803	PATU8988S	viability after 35 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.18616229614463498	[1434]	[678,635,NaN]	2	hSpCas9	negative selection	9822252
37120121	37120144	2	+	27869803	PATU8988S	viability after 35 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-0.6393516016136722	[283]	[43,102,NaN]	-6	hSpCas9	negative selection	9822253
37109265	37109288	2	-	27869803	PATU8988S	viability after 31 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	-0.030810000311715352	[490]	[221,152,NaN]	0	hSpCas9	negative selection	9904700
37114730	37114753	2	-	27869803	PATU8988S	viability after 31 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.09000041931379066	[1434]	[557,673,NaN]	1	hSpCas9	negative selection	9904701
37120121	37120144	2	+	27869803	PATU8988S	viability after 31 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	0.1438646247382488	[283]	[114,137,NaN]	1	hSpCas9	negative selection	9904702
37109265	37109288	2	-	27869803	HPAFII	viability after 35 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.6172021483902176	[276]	[57,391,NaN]	4	hSpCas9	negative selection	9987149
37114730	37114753	2	-	27869803	HPAFII	viability after 35 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.6396140706196274	[843]	[794,519,NaN]	4	hSpCas9	negative selection	9987150
37120121	37120144	2	+	27869803	HPAFII	viability after 35 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	-1.1447232723333742	[82]	[26,9,NaN]	-6	hSpCas9	negative selection	9987151
37109265	37109288	2	-	27869803	HPAFII	viability after 31 days	GCAAGACTATGGAAAGGAAGTGG	EIF2AK2	ENSG00000055332	0.38440644562382453	[276]	[55,362,NaN]	2	hSpCas9	negative selection	10069598
37114730	37114753	2	-	27869803	HPAFII	viability after 31 days	GCGATACATGAGCCCAGAACAGG	EIF2AK2	ENSG00000055332	0.42324177085370884	[843]	[593,679,NaN]	3	hSpCas9	negative selection	10069599
37120121	37120144	2	+	27869803	HPAFII	viability after 31 days	AAGGCACTTAGTCTTTGACCTGG	EIF2AK2	ENSG00000055332	0.48986560105691357	[82]	[96,30,NaN]	3	hSpCas9	negative selection	10069600
37138547	37138570	2	+	28162770	P31FUJ	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.13677126270809198	[273]	[353]	1	hSpCas9	negative selection	10148843
37138340	37138363	2	-	28162770	P31FUJ	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.14085137409934612	[388]	[503]	1	hSpCas9	negative selection	10148844
37122636	37122659	2	-	28162770	P31FUJ	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.30218044723009563	[371]	[538]	3	hSpCas9	negative selection	10148845
37146929	37146952	2	-	28162770	P31FUJ	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.7390741946712333	[258]	[507]	8	hSpCas9	negative selection	10148846
37141630	37141653	2	+	28162770	P31FUJ	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.3195819271955199	[417]	[612]	3	hSpCas9	negative selection	10148847
37109241	37109264	2	+	28162770	P31FUJ	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	1.0183301123631234	[70]	[168]	9	hSpCas9	negative selection	10148848
37147734	37147757	2	+	28162770	P31FUJ	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.19994873598167562	[768]	[1037]	2	hSpCas9	negative selection	10148849
37122544	37122567	2	+	28162770	P31FUJ	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.13791296387917057	[156]	[202]	1	hSpCas9	negative selection	10148850
37147679	37147702	2	+	28162770	P31FUJ	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.16349992545615533	[568]	[596]	-1	hSpCas9	negative selection	10148851
37141570	37141593	2	-	28162770	P31FUJ	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.699313217351279	[445]	[850]	7	hSpCas9	negative selection	10148852
37138547	37138570	2	+	28162770	TF1	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[237]	1	hSpCas9	negative selection	10318209
37138340	37138363	2	-	28162770	TF1	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10318210
37122636	37122659	2	-	28162770	TF1	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[323]	1	hSpCas9	negative selection	10318211
37146929	37146952	2	-	28162770	TF1	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[361]	1	hSpCas9	negative selection	10318212
37141630	37141653	2	+	28162770	TF1	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[223]	1	hSpCas9	negative selection	10318213
37109241	37109264	2	+	28162770	TF1	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10318214
37147734	37147757	2	+	28162770	TF1	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[560]	1	hSpCas9	negative selection	10318215
37122544	37122567	2	+	28162770	TF1	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10318216
37147679	37147702	2	+	28162770	TF1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[282]	1	hSpCas9	negative selection	10318217
37141570	37141593	2	-	28162770	TF1	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	NaN	[NaN]	[737]	1	hSpCas9	negative selection	10318218
37138547	37138570	2	+	28162770	SKM1	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	-0.07354046501796985	[74]	[125]	0	hSpCas9	negative selection	10487575
37138340	37138363	2	-	28162770	SKM1	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.3747990094117013	[64]	[148]	3	hSpCas9	negative selection	10487576
37122636	37122659	2	-	28162770	SKM1	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.1841505289595895	[116]	[234]	1	hSpCas9	negative selection	10487577
37146929	37146952	2	-	28162770	SKM1	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.7629608026991508	[67]	[203]	7	hSpCas9	negative selection	10487578
37141630	37141653	2	+	28162770	SKM1	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.5555999945545156	[121]	[316]	5	hSpCas9	negative selection	10487579
37109241	37109264	2	+	28162770	SKM1	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.35857054761981555	[14]	[33]	3	hSpCas9	negative selection	10487580
37147734	37147757	2	+	28162770	SKM1	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.13733568068757473	[190]	[306]	-1	hSpCas9	negative selection	10487581
37122544	37122567	2	+	28162770	SKM1	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.23689199103156294	[35]	[74]	2	hSpCas9	negative selection	10487582
37147679	37147702	2	+	28162770	SKM1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.8500160741916022	[103]	[101]	-6	hSpCas9	negative selection	10487583
37141570	37141593	2	-	28162770	SKM1	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.2783032077736798	[124]	[267]	2	hSpCas9	negative selection	10487584
37138547	37138570	2	+	28162770	SKM1	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	-0.07354046501796985	[74]	[125]	0	hSpCas9	negative selection	10656941
37138340	37138363	2	-	28162770	SKM1	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.3747990094117013	[64]	[148]	3	hSpCas9	negative selection	10656942
37122636	37122659	2	-	28162770	SKM1	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.1841505289595895	[116]	[234]	1	hSpCas9	negative selection	10656943
37146929	37146952	2	-	28162770	SKM1	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.7629608026991508	[67]	[203]	7	hSpCas9	negative selection	10656944
37141630	37141653	2	+	28162770	SKM1	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.5555999945545156	[121]	[316]	5	hSpCas9	negative selection	10656945
37109241	37109264	2	+	28162770	SKM1	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.35857054761981555	[14]	[33]	3	hSpCas9	negative selection	10656946
37147734	37147757	2	+	28162770	SKM1	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.13733568068757473	[190]	[306]	-1	hSpCas9	negative selection	10656947
37122544	37122567	2	+	28162770	SKM1	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.23689199103156294	[35]	[74]	2	hSpCas9	negative selection	10656948
37147679	37147702	2	+	28162770	SKM1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.8500160741916022	[103]	[101]	-6	hSpCas9	negative selection	10656949
37141570	37141593	2	-	28162770	SKM1	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.2783032077736798	[124]	[267]	2	hSpCas9	negative selection	10656950
37138547	37138570	2	+	28162770	PL21	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	-0.22984822625549511	[290]	[107]	-2	hSpCas9	negative selection	10826307
37138340	37138363	2	-	28162770	PL21	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	-0.037724215609567735	[249]	[105]	0	hSpCas9	negative selection	10826308
37122636	37122659	2	-	28162770	PL21	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.2222785917585688	[387]	[196]	2	hSpCas9	negative selection	10826309
37146929	37146952	2	-	28162770	PL21	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.7232368596256168	[269]	[193]	6	hSpCas9	negative selection	10826310
37141630	37141653	2	+	28162770	PL21	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	-0.1820060032321491	[476]	[182]	-1	hSpCas9	negative selection	10826311
37109241	37109264	2	+	28162770	PL21	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.5510467763484486	[68]	[43]	5	hSpCas9	negative selection	10826312
37147734	37147757	2	+	28162770	PL21	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.3096745667939129	[785]	[423]	2	hSpCas9	negative selection	10826313
37122544	37122567	2	+	28162770	PL21	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.6437462659649348	[124]	[84]	5	hSpCas9	negative selection	10826314
37147679	37147702	2	+	28162770	PL21	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.33661379318921614	[411]	[141]	-2	hSpCas9	negative selection	10826315
37141570	37141593	2	-	28162770	PL21	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	-0.11653275494654702	[410]	[164]	-1	hSpCas9	negative selection	10826316
37138547	37138570	2	+	28162770	P31FUJ	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.13677126270809198	[273]	[353]	1	hSpCas9	negative selection	10995673
37138340	37138363	2	-	28162770	P31FUJ	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.14085137409934612	[388]	[503]	1	hSpCas9	negative selection	10995674
37122636	37122659	2	-	28162770	P31FUJ	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.30218044723009563	[371]	[538]	3	hSpCas9	negative selection	10995675
37146929	37146952	2	-	28162770	P31FUJ	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.7390741946712333	[258]	[507]	8	hSpCas9	negative selection	10995676
37141630	37141653	2	+	28162770	P31FUJ	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.3195819271955199	[417]	[612]	3	hSpCas9	negative selection	10995677
37109241	37109264	2	+	28162770	P31FUJ	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	1.0183301123631234	[70]	[168]	9	hSpCas9	negative selection	10995678
37147734	37147757	2	+	28162770	P31FUJ	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.19994873598167562	[768]	[1037]	2	hSpCas9	negative selection	10995679
37122544	37122567	2	+	28162770	P31FUJ	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.13791296387917057	[156]	[202]	1	hSpCas9	negative selection	10995680
37147679	37147702	2	+	28162770	P31FUJ	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.16349992545615533	[568]	[596]	-1	hSpCas9	negative selection	10995681
37141570	37141593	2	-	28162770	P31FUJ	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.699313217351279	[445]	[850]	7	hSpCas9	negative selection	10995682
37138547	37138570	2	+	28162770	OCIAML5	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.459292282313178	[136]	[339]	4	hSpCas9	negative selection	11165039
37138340	37138363	2	-	28162770	OCIAML5	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	-0.10625005911552521	[194]	[326]	-1	hSpCas9	negative selection	11165040
37122636	37122659	2	-	28162770	OCIAML5	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.6770426951236416	[157]	[455]	6	hSpCas9	negative selection	11165041
37146929	37146952	2	-	28162770	OCIAML5	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.23680217763506162	[180]	[384]	2	hSpCas9	negative selection	11165042
37141630	37141653	2	+	28162770	OCIAML5	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.28543695288593796	[244]	[538]	2	hSpCas9	negative selection	11165043
37109241	37109264	2	+	28162770	OCIAML5	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.4628067664894149	[40]	[101]	4	hSpCas9	negative selection	11165044
37147734	37147757	2	+	28162770	OCIAML5	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.4811210618802422	[484]	[1221]	4	hSpCas9	negative selection	11165045
37122544	37122567	2	+	28162770	OCIAML5	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	-0.9794458773402244	[141]	[129]	-6	hSpCas9	negative selection	11165046
37147679	37147702	2	+	28162770	OCIAML5	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.08538027857779118	[220]	[375]	0	hSpCas9	negative selection	11165047
37141570	37141593	2	-	28162770	OCIAML5	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.32036093778148556	[255]	[576]	2	hSpCas9	negative selection	11165048
37138547	37138570	2	+	28162770	EOL1	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.027958096652061504	[470]	[252]	0	hSpCas9	negative selection	11334405
37138340	37138363	2	-	28162770	EOL1	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	-1.3880424587374915	[307]	[61]	-7	hSpCas9	negative selection	11334406
37122636	37122659	2	-	28162770	EOL1	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.06400220169063076	[738]	[406]	0	hSpCas9	negative selection	11334407
37146929	37146952	2	-	28162770	EOL1	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.7990168894866757	[563]	[516]	7	hSpCas9	negative selection	11334408
37141630	37141653	2	+	28162770	EOL1	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.47149694635495965	[986]	[720]	4	hSpCas9	negative selection	11334409
37109241	37109264	2	+	28162770	EOL1	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	-0.03892635240435127	[116]	[59]	0	hSpCas9	negative selection	11334410
37147734	37147757	2	+	28162770	EOL1	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.40428869265900547	[941]	[374]	-3	hSpCas9	negative selection	11334411
37122544	37122567	2	+	28162770	EOL1	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.3635907338601677	[148]	[100]	3	hSpCas9	negative selection	11334412
37147679	37147702	2	+	28162770	EOL1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.4937648597411701	[440]	[164]	-4	hSpCas9	negative selection	11334413
37141570	37141593	2	-	28162770	EOL1	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	1.4834815629624765	[521]	[768]	9	hSpCas9	negative selection	11334414
37138547	37138570	2	+	28162770	MOLM13	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	-0.2703523693088978	[376]	[225]	-2	hSpCas9	negative selection	11503771
37138340	37138363	2	-	28162770	MOLM13	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	-0.4399407745275542	[575]	[306]	-3	hSpCas9	negative selection	11503772
37122636	37122659	2	-	28162770	MOLM13	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.11974109644102637	[582]	[457]	0	hSpCas9	negative selection	11503773
37146929	37146952	2	-	28162770	MOLM13	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.36466866118580843	[419]	[390]	2	hSpCas9	negative selection	11503774
37141630	37141653	2	+	28162770	MOLM13	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.8715606258734776	[668]	[884]	6	hSpCas9	negative selection	11503775
37109241	37109264	2	+	28162770	MOLM13	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.04731369872430524	[86]	[64]	0	hSpCas9	negative selection	11503776
37147734	37147757	2	+	28162770	MOLM13	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.20220764459051388	[1334]	[838]	-1	hSpCas9	negative selection	11503777
37122544	37122567	2	+	28162770	MOLM13	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	-0.200904709980048	[247]	[155]	-1	hSpCas9	negative selection	11503778
37147679	37147702	2	+	28162770	MOLM13	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.8828673664020021	[833]	[326]	-5	hSpCas9	negative selection	11503779
37141570	37141593	2	-	28162770	MOLM13	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.6478173511721691	[526]	[596]	5	hSpCas9	negative selection	11503780
37138547	37138570	2	+	28162770	HEL	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.281640139832317	[279]	[217]	2	hSpCas9	negative selection	11673137
37138340	37138363	2	-	28162770	HEL	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	-1.3240943040644437	[429]	[109]	-6	hSpCas9	negative selection	11673138
37122636	37122659	2	-	28162770	HEL	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	-0.16616487715273376	[465]	[265]	-1	hSpCas9	negative selection	11673139
37146929	37146952	2	-	28162770	HEL	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	1.1096884199216706	[347]	[480]	8	hSpCas9	negative selection	11673140
37141630	37141653	2	+	28162770	HEL	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.6114531430734098	[605]	[592]	5	hSpCas9	negative selection	11673141
37109241	37109264	2	+	28162770	HEL	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	1.659612650564753	[84]	[171]	9	hSpCas9	negative selection	11673142
37147734	37147757	2	+	28162770	HEL	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	-0.8055611214102352	[935]	[342]	-5	hSpCas9	negative selection	11673143
37122544	37122567	2	+	28162770	HEL	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.038966481504442374	[192]	[126]	0	hSpCas9	negative selection	11673144
37147679	37147702	2	+	28162770	HEL	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-1.0480783013619597	[522]	[161]	-6	hSpCas9	negative selection	11673145
37141570	37141593	2	-	28162770	HEL	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.5967264342435207	[445]	[431]	5	hSpCas9	negative selection	11673146
37138547	37138570	2	+	28162770	MV411	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	1.0384035123013462	[214]	[371]	8	hSpCas9	negative selection	11842503
37138340	37138363	2	-	28162770	MV411	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	1.2445492714579487	[249]	[498]	9	hSpCas9	negative selection	11842504
37122636	37122659	2	-	28162770	MV411	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.4285255973027714	[328]	[372]	4	hSpCas9	negative selection	11842505
37146929	37146952	2	-	28162770	MV411	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.49635084837191645	[307]	[365]	4	hSpCas9	negative selection	11842506
37141630	37141653	2	+	28162770	MV411	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.5539505932834501	[413]	[511]	5	hSpCas9	negative selection	11842507
37109241	37109264	2	+	28162770	MV411	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	-0.1675999484960684	[59]	[44]	-1	hSpCas9	negative selection	11842508
37147734	37147757	2	+	28162770	MV411	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.11120793002147367	[565]	[514]	0	hSpCas9	negative selection	11842509
37122544	37122567	2	+	28162770	MV411	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.5005564877514864	[145]	[173]	4	hSpCas9	negative selection	11842510
37147679	37147702	2	+	28162770	MV411	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.34750903851100284	[289]	[191]	-3	hSpCas9	negative selection	11842511
37141570	37141593	2	-	28162770	MV411	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	-0.011854453365201634	[461]	[385]	0	hSpCas9	negative selection	11842512
37138547	37138570	2	+	28162770	MONOMAC1	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.1337150982148148	[162]	[204]	1	hSpCas9	negative selection	12011869
37138340	37138363	2	-	28162770	MONOMAC1	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.9893762771713277	[173]	[395]	8	hSpCas9	negative selection	12011870
37122636	37122659	2	-	28162770	MONOMAC1	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.6121408106048681	[225]	[395]	6	hSpCas9	negative selection	12011871
37146929	37146952	2	-	28162770	MONOMAC1	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	0.08819330488843624	[214]	[261]	0	hSpCas9	negative selection	12011872
37141630	37141653	2	+	28162770	MONOMAC1	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.026058813404096215	[292]	[341]	0	hSpCas9	negative selection	12011873
37109241	37109264	2	+	28162770	MONOMAC1	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	-0.3345403708094885	[43]	[39]	-3	hSpCas9	negative selection	12011874
37147734	37147757	2	+	28162770	MONOMAC1	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.44266861825603465	[361]	[563]	4	hSpCas9	negative selection	12011875
37122544	37122567	2	+	28162770	MONOMAC1	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	1.3163723926365685	[61]	[176]	9	hSpCas9	negative selection	12011876
37147679	37147702	2	+	28162770	MONOMAC1	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	-0.049968459274084776	[204]	[226]	0	hSpCas9	negative selection	12011877
37141570	37141593	2	-	28162770	MONOMAC1	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.5661292192155127	[250]	[425]	5	hSpCas9	negative selection	12011878
37138547	37138570	2	+	28162770	OCIAML2	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	1.5074395346883362	[28]	[456]	9	hSpCas9	negative selection	12181235
37138340	37138363	2	-	28162770	OCIAML2	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	1.3028391026630333	[39]	[546]	9	hSpCas9	negative selection	12181236
37122636	37122659	2	-	28162770	OCIAML2	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.3217125259604182	[68]	[477]	3	hSpCas9	negative selection	12181237
37146929	37146952	2	-	28162770	OCIAML2	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	1.1370527519790783	[41]	[511]	9	hSpCas9	negative selection	12181238
37141630	37141653	2	+	28162770	OCIAML2	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.22703280822835725	[79]	[518]	2	hSpCas9	negative selection	12181239
37109241	37109264	2	+	28162770	OCIAML2	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.03838382224569625	[12]	[73]	0	hSpCas9	negative selection	12181240
37147734	37147757	2	+	28162770	OCIAML2	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.17557030500086257	[122]	[769]	1	hSpCas9	negative selection	12181241
37122544	37122567	2	+	28162770	OCIAML2	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.9101919586987697	[23]	[249]	8	hSpCas9	negative selection	12181242
37147679	37147702	2	+	28162770	OCIAML2	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	0.24557720875724742	[55]	[367]	2	hSpCas9	negative selection	12181243
37141570	37141593	2	-	28162770	OCIAML2	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.8200473356607615	[55]	[547]	7	hSpCas9	negative selection	12181244
37138547	37138570	2	+	28162770	OCIAML3	viability	CGTAGTAGCAAAAGAACCAGAGG	EIF2AK2	ENSG00000055332	0.7513794273871882	[60]	[309]	6	hSpCas9	negative selection	12350601
37138340	37138363	2	-	28162770	OCIAML3	viability	GCTTCTGAATCATCATCTGAAGG	EIF2AK2	ENSG00000055332	0.9742761192503626	[57]	[343]	8	hSpCas9	negative selection	12350602
37122636	37122659	2	-	28162770	OCIAML3	viability	GGAGCGTGAAGTAAAAGCATTGG	EIF2AK2	ENSG00000055332	0.06085687362714931	[93]	[295]	0	hSpCas9	negative selection	12350603
37146929	37146952	2	-	28162770	OCIAML3	viability	GATGGAAGAGAATTTCCAGAAGG	EIF2AK2	ENSG00000055332	1.4165616013860243	[67]	[547]	9	hSpCas9	negative selection	12350604
37141630	37141653	2	+	28162770	OCIAML3	viability	AAGGCCTATGTAATTCCCCATGG	EIF2AK2	ENSG00000055332	0.07976412735484906	[125]	[401]	0	hSpCas9	negative selection	12350605
37109241	37109264	2	+	28162770	OCIAML3	viability	GAATTAGCCCCAAAGCGTAGAGG	EIF2AK2	ENSG00000055332	0.6913945785380851	[15]	[77]	6	hSpCas9	negative selection	12350606
37147734	37147757	2	+	28162770	OCIAML3	viability	GTACTACTCCCTGCTTCTGACGG	EIF2AK2	ENSG00000055332	0.13717560124803674	[149]	[497]	1	hSpCas9	negative selection	12350607
37122544	37122567	2	+	28162770	OCIAML3	viability	GCTCTCAAGAGAATCATCACTGG	EIF2AK2	ENSG00000055332	0.5214695770957729	[35]	[155]	5	hSpCas9	negative selection	12350608
37147679	37147702	2	+	28162770	OCIAML3	viability	GCAACCTACCTCCTATCATGTGG	EIF2AK2	ENSG00000055332	0.11406540271935639	[115]	[378]	1	hSpCas9	negative selection	12350609
37141570	37141593	2	-	28162770	OCIAML3	viability	ATTATGAACAGTGTGCATCGGGG	EIF2AK2	ENSG00000055332	0.36609963255232403	[109]	[427]	3	hSpCas9	negative selection	12350610