Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:1965
• Symbol:EIF2S1
• Description:eukaryotic translation initiation factor 2 subunit alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/EIF2S1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
67382462	67382485	14	-	26472758	Jiyoye	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-4.116386574551139	[183]	[7]	-9	hSpCas9	negative selection	49251
67376521	67376544	14	-	26472758	Jiyoye	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.2577864412805027	[240]	[18]	-9	hSpCas9	negative selection	49252
67376465	67376488	14	+	26472758	Jiyoye	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-2.0289237333008	[91]	[16]	-8	hSpCas9	negative selection	49253
67381634	67381657	14	+	26472758	Jiyoye	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	49254
67382546	67382569	14	+	26472758	Jiyoye	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-1.9584740908108071	[66]	[12]	-8	hSpCas9	negative selection	49255
67364809	67364832	14	+	26472758	Jiyoye	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-5.914752713381489	[319]	[3]	-9	hSpCas9	negative selection	49256
67364974	67364997	14	+	26472758	Jiyoye	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-1.0257840257702329	[80]	[29]	-6	hSpCas9	negative selection	49257
67382518	67382541	14	-	26472758	Jiyoye	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-4.329790212660333	[79]	[2]	-9	hSpCas9	negative selection	49258
67380744	67380767	14	+	26472758	Jiyoye	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.5928246184941273	[1]	[0]	-4	hSpCas9	negative selection	49259
67382486	67382509	14	+	26472758	Jiyoye	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-2.2735461020207137	[108]	[16]	-8	hSpCas9	negative selection	49260
67382462	67382485	14	-	26472758	KBM7	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-5.169161149984727	[585,531]	[10,3]	-9	hSpCas9	negative selection	240369
67376521	67376544	14	-	26472758	KBM7	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.707117038699458	[972,1072]	[42,31]	-9	hSpCas9	negative selection	240370
67376465	67376488	14	+	26472758	KBM7	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-0.9630281676670116	[623,435]	[132,119]	-6	hSpCas9	negative selection	240371
67381634	67381657	14	+	26472758	KBM7	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-3.964144113711266	[400,230]	[12,5]	-9	hSpCas9	negative selection	240372
67382546	67382569	14	+	26472758	KBM7	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-3.4524171432424744	[504,383]	[10,25]	-9	hSpCas9	negative selection	240373
67364809	67364832	14	+	26472758	KBM7	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-2.987002697001908	[1572,1154]	[107,54]	-9	hSpCas9	negative selection	240374
67364974	67364997	14	+	26472758	KBM7	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-1.6674038930953363	[242,225]	[29,38]	-8	hSpCas9	negative selection	240375
67382518	67382541	14	-	26472758	KBM7	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-2.421171514602137	[374,362]	[41,23]	-9	hSpCas9	negative selection	240376
67380744	67380767	14	+	26472758	KBM7	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.15534837503018828	[312,150]	[67,118]	-1	hSpCas9	negative selection	240377
67382486	67382509	14	+	26472758	KBM7	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-1.7222964227110515	[523,480]	[68,73]	-8	hSpCas9	negative selection	240378
67382462	67382485	14	-	26472758	Raji	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-5.750597459753973	[231]	[0]	-9	hSpCas9	negative selection	431487
67376521	67376544	14	-	26472758	Raji	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.1656349590328166	[579]	[14]	-9	hSpCas9	negative selection	431488
67376465	67376488	14	+	26472758	Raji	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-3.775259513988242	[294]	[4]	-9	hSpCas9	negative selection	431489
67381634	67381657	14	+	26472758	Raji	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-4.8698963881263175	[125]	[0]	-9	hSpCas9	negative selection	431490
67382546	67382569	14	+	26472758	Raji	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-4.10206983025535	[295]	[3]	-9	hSpCas9	negative selection	431491
67364809	67364832	14	+	26472758	Raji	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.4233979271964934	[600]	[12]	-9	hSpCas9	negative selection	431492
67364974	67364997	14	+	26472758	Raji	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-5.485073501894481	[192]	[0]	-9	hSpCas9	negative selection	431493
67382518	67382541	14	-	26472758	Raji	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-0.8490271960787178	[162]	[20]	-6	hSpCas9	negative selection	431494
67380744	67380767	14	+	26472758	Raji	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-5.236912372542218	[324]	[1]	-9	hSpCas9	negative selection	431495
67382486	67382509	14	+	26472758	Raji	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-3.82807621243169	[305]	[4]	-9	hSpCas9	negative selection	431496
67382462	67382485	14	-	26472758	K562	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-7.635164521946336	[470]	[1]	-9	hSpCas9	negative selection	622605
67376521	67376544	14	-	26472758	K562	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-5.432352084581012	[664]	[12]	-9	hSpCas9	negative selection	622606
67376465	67376488	14	+	26472758	K562	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-2.180602860185019	[434]	[80]	-7	hSpCas9	negative selection	622607
67381634	67381657	14	+	26472758	K562	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-8.243421306156604	[358]	[0]	-9	hSpCas9	negative selection	622608
67382546	67382569	14	+	26472758	K562	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-5.445579243752999	[412]	[7]	-9	hSpCas9	negative selection	622609
67364809	67364832	14	+	26472758	K562	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-5.227256486725597	[1064]	[23]	-9	hSpCas9	negative selection	622610
67364974	67364997	14	+	26472758	K562	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-6.890007592554479	[280]	[1]	-9	hSpCas9	negative selection	622611
67382518	67382541	14	-	26472758	K562	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-3.9563436776984586	[330]	[17]	-9	hSpCas9	negative selection	622612
67380744	67380767	14	+	26472758	K562	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-2.181846027035651	[214]	[39]	-7	hSpCas9	negative selection	622613
67382486	67382509	14	+	26472758	K562	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-1.0612890147625849	[397]	[160]	-5	hSpCas9	negative selection	622614
67376532	67376555	14	+	26627737	DLD1	viability	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-3.983165090737938	[171]	[4,0,3]	-9	hSpCas9	negative selection	789079
67382473	67382496	14	+	26627737	DLD1	viability	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-3.863074834302787	[1137]	[21,35,16]	-9	hSpCas9	negative selection	789080
67383341	67383364	14	+	26627737	DLD1	viability	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-1.3682783416463966	[99]	[23,0,10]	-8	hSpCas9	negative selection	789081
67376532	67376555	14	+	26627737	GBM cells	viability after 5 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-0.8924995033028971	[44]	[14,10]	-8	hSpCas9	negative selection	871394
67382473	67382496	14	+	26627737	GBM cells	viability after 5 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.9084410471719186	[391]	[28,26]	-9	hSpCas9	negative selection	871395
67383341	67383364	14	+	26627737	GBM cells	viability after 5 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-1.3932668766076248	[119]	[38,9]	-9	hSpCas9	negative selection	871396
67376532	67376555	14	+	26627737	GBM cells	viability after 13 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-1.8754388320309991	[44]	[4,7]	-9	hSpCas9	negative selection	953709
67382473	67382496	14	+	26627737	GBM cells	viability after 13 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-3.570956109073372	[391]	[18,16]	-9	hSpCas9	negative selection	953710
67383341	67383364	14	+	26627737	GBM cells	viability after 13 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-1.6471941454492351	[119]	[6,31]	-9	hSpCas9	negative selection	953711
67376532	67376555	14	+	26627737	GBM cells	viability after 21 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-4.611619796714017	[44]	[0,0]	-9	hSpCas9	negative selection	1036024
67382473	67382496	14	+	26627737	GBM cells	viability after 21 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-4.412548449612187	[391]	[9,9]	-9	hSpCas9	negative selection	1036025
67383341	67383364	14	+	26627737	GBM cells	viability after 21 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-1.9467577488189893	[119]	[18,14]	-8	hSpCas9	negative selection	1036026
67376532	67376555	14	+	26627737	RPE1	viability after 9 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-0.8525013202883343	[86]	[25,0]	-6	hSpCas9	negative selection	1118339
67382473	67382496	14	+	26627737	RPE1	viability after 9 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.7764667783563126	[681]	[98,14]	-8	hSpCas9	negative selection	1118340
67383341	67383364	14	+	26627737	RPE1	viability after 9 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	3.4074016743278226	[12]	[40,45]	9	hSpCas9	negative selection	1118341
67376532	67376555	14	+	26627737	RPE1	viability after 12 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-1.5112081744448687	[86]	[14,0]	-8	hSpCas9	negative selection	1200654
67382473	67382496	14	+	26627737	RPE1	viability after 12 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.568648726561351	[681]	[104,15]	-8	hSpCas9	negative selection	1200655
67383341	67383364	14	+	26627737	RPE1	viability after 12 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	1.3564075235196968	[12]	[6,10]	7	hSpCas9	negative selection	1200656
67376532	67376555	14	+	26627737	RPE1	viability after 15 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-4.621194621976834	[86]	[0,0]	-9	hSpCas9	negative selection	1282969
67382473	67382496	14	+	26627737	RPE1	viability after 15 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.8803716904799122	[681]	[57,46]	-8	hSpCas9	negative selection	1282970
67383341	67383364	14	+	26627737	RPE1	viability after 15 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	2.715084726258268	[12]	[43,4]	9	hSpCas9	negative selection	1282971
67376532	67376555	14	+	26627737	RPE1	viability after 18 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-4.553275235747986	[86]	[0,0]	-9	hSpCas9	negative selection	1365284
67382473	67382496	14	+	26627737	RPE1	viability after 18 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.080937584212316	[681]	[57,117]	-6	hSpCas9	negative selection	1365285
67383341	67383364	14	+	26627737	RPE1	viability after 18 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	3.031325625469202	[12]	[33,22]	9	hSpCas9	negative selection	1365286
67376532	67376555	14	+	26627737	HeLa	viability after 8 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-2.414603590627449	[139]	[33,4,0]	-9	hSpCas9	negative selection	1447599
67382473	67382496	14	+	26627737	HeLa	viability after 8 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.0535174401619884	[398]	[88,21,25]	-9	hSpCas9	negative selection	1447600
67383341	67383364	14	+	26627737	HeLa	viability after 8 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-0.593412937015168	[107]	[31,35,25]	-5	hSpCas9	negative selection	1447601
67376532	67376555	14	+	26627737	HeLa	viability after 12 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-0.8565838762540425	[139]	[47,34,12]	-7	hSpCas9	negative selection	1529914
67382473	67382496	14	+	26627737	HeLa	viability after 12 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.320248865792438	[398]	[4,72,15]	-9	hSpCas9	negative selection	1529915
67383341	67383364	14	+	26627737	HeLa	viability after 12 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	0.00759666839295603	[107]	[47,41,44]	0	hSpCas9	negative selection	1529916
67376532	67376555	14	+	26627737	HeLa	viability after 15 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-2.931557422395459	[139]	[0,19,0]	-9	hSpCas9	negative selection	1612229
67382473	67382496	14	+	26627737	HeLa	viability after 15 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.90078440185624	[398]	[18,53,58]	-9	hSpCas9	negative selection	1612230
67383341	67383364	14	+	26627737	HeLa	viability after 15 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-0.21299537013449088	[107]	[28,57,25]	-2	hSpCas9	negative selection	1612231
67376532	67376555	14	+	26627737	HeLa	viability after 18 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-3.1132361137716336	[139]	[0,13,0]	-9	hSpCas9	negative selection	1694544
67382473	67382496	14	+	26627737	HeLa	viability after 18 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.8960026485105386	[398]	[11,45,58]	-9	hSpCas9	negative selection	1694545
67383341	67383364	14	+	26627737	HeLa	viability after 18 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-0.12350904919402517	[107]	[20,51,25]	-1	hSpCas9	negative selection	1694546
67376532	67376555	14	+	26627737	HCT116	viability after 6 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-4.77368323866116	[173]	[0,0]	-9	hSpCas9	negative selection	1776859
67382473	67382496	14	+	26627737	HCT116	viability after 6 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-3.649220691494842	[1049]	[7,15]	-9	hSpCas9	negative selection	1776860
67383341	67383364	14	+	26627737	HCT116	viability after 6 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	0.09967668260304108	[332]	[155,0]	0	hSpCas9	negative selection	1776861
67376532	67376555	14	+	26627737	HCT116	viability after 8 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-1.787664803117334	[62]	[6,3,18]	-9	hSpCas9	negative selection	1859174
67382473	67382496	14	+	26627737	HCT116	viability after 8 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.2823927744883714	[459]	[42,48,63]	-9	hSpCas9	negative selection	1859175
67383341	67383364	14	+	26627737	HCT116	viability after 8 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	0.8660527238135622	[52]	[77,17,63]	7	hSpCas9	negative selection	1859176
67376532	67376555	14	+	26627737	HCT116	viability after 9 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-5.53795368449526	[173]	[0,0]	-9	hSpCas9	negative selection	1941489
67382473	67382496	14	+	26627737	HCT116	viability after 9 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-6.437759633727071	[1049]	[0,4]	-9	hSpCas9	negative selection	1941490
67383341	67383364	14	+	26627737	HCT116	viability after 9 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	0.5451771295467777	[332]	[31,206]	4	hSpCas9	negative selection	1941491
67376532	67376555	14	+	26627737	HCT116	viability after 12 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-1.8967244189608996	[62]	[2,0,22]	-9	hSpCas9	negative selection	2023804
67382473	67382496	14	+	26627737	HCT116	viability after 12 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.0437003082146346	[459]	[36,66,73]	-9	hSpCas9	negative selection	2023805
67383341	67383364	14	+	26627737	HCT116	viability after 12 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	1.4295815925973234	[52]	[130,26,60]	9	hSpCas9	negative selection	2023806
67376532	67376555	14	+	26627737	HCT116	viability after 15 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-0.7476890617606058	[62]	[10,0,50]	-6	hSpCas9	negative selection	2106119
67382473	67382496	14	+	26627737	HCT116	viability after 15 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.4611762714193026	[459]	[124,38,126]	-8	hSpCas9	negative selection	2106120
67383341	67383364	14	+	26627737	HCT116	viability after 15 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	0.9656686963255079	[52]	[66,31,79]	7	hSpCas9	negative selection	2106121
67376532	67376555	14	+	26627737	HCT116	viability after 18 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-4.222117660958059	[62]	[0,0,2]	-9	hSpCas9	negative selection	2188434
67382473	67382496	14	+	26627737	HCT116	viability after 18 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.6645980399614535	[459]	[89,22,101]	-8	hSpCas9	negative selection	2188435
67383341	67383364	14	+	26627737	HCT116	viability after 18 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	1.5091271193791769	[52]	[172,12,34]	9	hSpCas9	negative selection	2188436
67364753	67364776	14	+	24336569	HL60	viability	TGTTTAAATTGCAGAATGCCGGG	EIF2S1	ENSG00000134001	0.24190237427880035	[801]	[2006]	2	hSpCas9	negative selection	2262369
67364791	67364814	14	+	24336569	HL60	viability	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	-2.155811442088978	[875]	[415]	-9	hSpCas9	negative selection	2262370
67364807	67364830	14	-	24336569	HL60	viability	ATCACTACATCTTCCACCTCAGG	EIF2S1	ENSG00000134001	0.1776231206882347	[426]	[1021]	1	hSpCas9	negative selection	2262371
67364836	67364859	14	+	24336569	HL60	viability	TGTCAGATCCATTGCTGAAATGG	EIF2S1	ENSG00000134001	0.1275699378525326	[464]	[1074]	1	hSpCas9	negative selection	2262372
67364876	67364899	14	+	24336569	HL60	viability	CTGGAATACAACAACATTGAAGG	EIF2S1	ENSG00000134001	-0.6771296029570884	[574]	[760]	-6	hSpCas9	negative selection	2262373
67364907	67364930	14	+	24336569	HL60	viability	TTCTTAGTGAATTATCCAGAAGG	EIF2S1	ENSG00000134001	-1.4138339422379054	[519]	[412]	-8	hSpCas9	negative selection	2262374
67364922	67364945	14	-	24336569	HL60	viability	GATAGAACGGATACGCCTTCTGG	EIF2S1	ENSG00000134001	0.07481877421849359	[790]	[1762]	0	hSpCas9	negative selection	2262375
67364935	67364958	14	-	24336569	HL60	viability	GGATGAGTTTGTTGATAGAACGG	EIF2S1	ENSG00000134001	-0.6226787059848848	[405]	[557]	-5	hSpCas9	negative selection	2262376
67364942	67364965	14	+	24336569	HL60	viability	ATCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-0.33271477995307663	[1072]	[1802]	-3	hSpCas9	negative selection	2262377
67364956	67364979	14	-	24336569	HL60	viability	CACACTCATTCCTGCCAATTCGG	EIF2S1	ENSG00000134001	0.6108684976089112	[301]	[975]	5	hSpCas9	negative selection	2262378
67364753	67364776	14	+	24336569	KBM7	viability	TGTTTAAATTGCAGAATGCCGGG	EIF2S1	ENSG00000134001	0.9464633191544101	[596]	[3137]	7	hSpCas9	negative selection	2329546
67364791	67364814	14	+	24336569	KBM7	viability	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	-3.7808226046640794	[639]	[126]	-9	hSpCas9	negative selection	2329547
67364807	67364830	14	-	24336569	KBM7	viability	ATCACTACATCTTCCACCTCAGG	EIF2S1	ENSG00000134001	-0.1442563418169155	[358]	[885]	-1	hSpCas9	negative selection	2329548
67364836	67364859	14	+	24336569	KBM7	viability	TGTCAGATCCATTGCTGAAATGG	EIF2S1	ENSG00000134001	1.6245389452592667	[277]	[2337]	9	hSpCas9	negative selection	2329549
67364876	67364899	14	+	24336569	KBM7	viability	CTGGAATACAACAACATTGAAGG	EIF2S1	ENSG00000134001	-2.0937158125150734	[553]	[353]	-8	hSpCas9	negative selection	2329550
67364907	67364930	14	+	24336569	KBM7	viability	TTCTTAGTGAATTATCCAGAAGG	EIF2S1	ENSG00000134001	-0.3530335600418819	[250]	[535]	-3	hSpCas9	negative selection	2329551
67364922	67364945	14	-	24336569	KBM7	viability	GATAGAACGGATACGCCTTCTGG	EIF2S1	ENSG00000134001	0.9657232513592138	[467]	[2492]	8	hSpCas9	negative selection	2329552
67364935	67364958	14	-	24336569	KBM7	viability	GGATGAGTTTGTTGATAGAACGG	EIF2S1	ENSG00000134001	-1.6558505096406775	[304]	[263]	-8	hSpCas9	negative selection	2329553
67364942	67364965	14	+	24336569	KBM7	viability	ATCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	0.3433007392077068	[540]	[1871]	3	hSpCas9	negative selection	2329554
67364956	67364979	14	-	24336569	KBM7	viability	CACACTCATTCCTGCCAATTCGG	EIF2S1	ENSG00000134001	1.425279770484845	[162]	[1193]	9	hSpCas9	negative selection	2329555
67360195	67360218	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGAGAAACAGTACTTTTCAGG	EIF2S1	ENSG00000134001	-1.8970188292418615	[236,176]	[13,8]	-9	dCas9-VP64	positive selection	2434642
67360122	67360145	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTCTTCAGAGGCAAGGAATCGG	EIF2S1	ENSG00000134001	0.19995582441989157	[360,441]	[131,68]	0	dCas9-VP64	positive selection	2434643
67360219	67360242	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGACGAATGTAGATCATGGAAGG	EIF2S1	ENSG00000134001	1.9362878522634541	[131,20]	[85,39]	6	dCas9-VP64	positive selection	2434644
67360116	67360139	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGATTCATTCTTCAGAGGCAAGG	EIF2S1	ENSG00000134001	3.0010934174829313	[8,17]	[26,20]	8	dCas9-VP64	positive selection	2446896
67360095	67360118	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTAGCTGAAACTTTGAAAGAGG	EIF2S1	ENSG00000134001	1.3690230437063178	[14,1]	[5,2]	5	dCas9-VP64	positive selection	2446897
67360148	67360171	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAAGGCGCGAGAAAGACATAGG	EIF2S1	ENSG00000134001	0.6527755132804447	[122,217]	[16,103]	3	dCas9-VP64	positive selection	2446898
67372012	67372035	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGCACTTTGGGAGGCCTAGG	EIF2S1	ENSG00000134001	1.206940593226964	[3,2]	[1,0]	5	dCas9-VP64	positive selection	2475666
67360195	67360218	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGAGAAACAGTACTTTTCAGG	EIF2S1	ENSG00000134001	0.3891330922398414	[36,55]	[18,19]	3	dCas9-VP64	positive selection	2529897
67360122	67360145	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTCTTCAGAGGCAAGGAATCGG	EIF2S1	ENSG00000134001	-0.5104259682459581	[336,281]	[70,69]	-5	dCas9-VP64	positive selection	2529898
67360219	67360242	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGACGAATGTAGATCATGGAAGG	EIF2S1	ENSG00000134001	-0.33846794011183057	[327,150]	[58,64]	-3	dCas9-VP64	positive selection	2529899
67360116	67360139	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGATTCATTCTTCAGAGGCAAGG	EIF2S1	ENSG00000134001	0.012802158970864286	[203,69]	[73,17]	0	dCas9-VP64	positive selection	2542151
67360095	67360118	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTAGCTGAAACTTTGAAAGAGG	EIF2S1	ENSG00000134001	-1.720469006307769	[39,228]	[4,19]	-9	dCas9-VP64	positive selection	2542152
67360148	67360171	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAAGGCGCGAGAAAGACATAGG	EIF2S1	ENSG00000134001	-0.7342153637815818	[105,405]	[24,71]	-7	dCas9-VP64	positive selection	2542153
67372012	67372035	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGCACTTTGGGAGGCCTAGG	EIF2S1	ENSG00000134001	0.18562790618715352	[12,24]	[5,7]	1	dCas9-VP64	positive selection	2570921
67376521	67376544	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	0.23182715584211655	[2,2]	[3,2]	5	hSpCas9	positive selection	2985404
67364975	67364998	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	0.3326606189349651	[2,2]	[2,3]	7	hSpCas9	positive selection	2985405
67376466	67376489	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	0.10849081224217882	[0,1]	[1,0]	2	hSpCas9	positive selection	2985406
67364792	67364815	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	-0.23735716673799073	[2,3]	[3,0]	-3	hSpCas9	positive selection	2985407
67376521	67376544	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-0.8875465634631159	[2,2]	[1,0]	-9	hSpCas9	positive selection	3053262
67364975	67364998	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-0.07460605354792249	[2,2]	[3,0]	-1	hSpCas9	positive selection	3053263
67376466	67376489	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	0.5935726857112384	[0,0]	[2,0]	8	hSpCas9	positive selection	3053264
67364792	67364815	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	-0.530344572225127	[2,2]	[1,0]	-7	hSpCas9	positive selection	3053265
67374484	67374507		+	24336571	A375	resistance to PLX after 7 days	AAAAAGAAGAGTTTCTCCAGAGG	EIF2S1	ENSG00000134001	-0.11700576754980663	[2,2]	[1,1]	-4	hSpCas9	positive selection	3111603
67376447	67376470		+	24336571	A375	resistance to PLX after 7 days	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	0.3905575557592957	[5,7]	[9,8]	8	hSpCas9	positive selection	3111604
67376521	67376544		-	24336571	A375	resistance to PLX after 7 days	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	0.254441211677116	[2,2]	[2,4]	7	hSpCas9	positive selection	3111605
67374500	67374523		-	24336571	A375	resistance to PLX after 7 days	TCACATTTGATTGCTTCCTCTGG	EIF2S1	ENSG00000134001	0.14020103712483056	[18,21]	[19,24]	4	hSpCas9	positive selection	3111606
67374484	67374507		+	24336571	A375	resistance to PLX after 14 days	AAAAAGAAGAGTTTCTCCAGAGG	EIF2S1	ENSG00000134001	0.5142033576840233	[2,1]	[1,1]	5	hSpCas9	positive selection	3169396
67376447	67376470		+	24336571	A375	resistance to PLX after 14 days	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.06803738172941498	[7,6]	[3,1]	0	hSpCas9	positive selection	3169397
67376521	67376544		-	24336571	A375	resistance to PLX after 14 days	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	0.7844045690664283	[1,3]	[1,1]	6	hSpCas9	positive selection	3169398
67374500	67374523		-	24336571	A375	resistance to PLX after 14 days	TCACATTTGATTGCTTCCTCTGG	EIF2S1	ENSG00000134001	0.1942955893736868	[14,15]	[7,7]	2	hSpCas9	positive selection	3169399
67374484	67374507		+	24336571	A375	viability after 7 days	AAAAAGAAGAGTTTCTCCAGAGG	EIF2S1	ENSG00000134001	-1.1400947378213986	[6]	[2,2]	-9	hSpCas9	negative selection	3227189
67376447	67376470		+	24336571	A375	viability after 7 days	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.170912238921498	[16]	[5,7]	-9	hSpCas9	negative selection	3227190
67376521	67376544		-	24336571	A375	viability after 7 days	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.7629409470807709	[12]	[2,2]	-9	hSpCas9	negative selection	3227191
67374500	67374523		-	24336571	A375	viability after 7 days	TCACATTTGATTGCTTCCTCTGG	EIF2S1	ENSG00000134001	-0.38333817074039267	[27]	[18,21]	-5	hSpCas9	negative selection	3227192
67374484	67374507		+	24336571	A375	viability after 14 days	AAAAAGAAGAGTTTCTCCAGAGG	EIF2S1	ENSG00000134001	-1.2153434391856552	[6]	[2,1]	-9	hSpCas9	negative selection	3284982
67376447	67376470		+	24336571	A375	viability after 14 days	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.0402704340625353	[16]	[7,6]	-8	hSpCas9	negative selection	3284983
67376521	67376544		-	24336571	A375	viability after 14 days	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.8383941348128523	[12]	[1,3]	-9	hSpCas9	negative selection	3284984
67374500	67374523		-	24336571	A375	viability after 14 days	TCACATTTGATTGCTTCCTCTGG	EIF2S1	ENSG00000134001	-0.7170998682004666	[27]	[14,15]	-7	hSpCas9	negative selection	3284985
67380744	67380767	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	2.5027879878316788	[25,27]	[0,0]	8	hSpCas9	positive selection	3347665
67376447	67376470	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	1.8496002438032435	[34,49]	[0,0]	7	hSpCas9	positive selection	3347666
67376521	67376544	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	2.705749879219226	[15,30]	[0,0]	8	hSpCas9	positive selection	3347667
67381634	67381657	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	2.7978945928085377	[21,21]	[0,0]	8	hSpCas9	positive selection	3366868
67380653	67380676	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	-1.1220521556254273	[332,332]	[0,0]	-7	hSpCas9	positive selection	3366869
67381669	67381692	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	-1.6253168379160061	[471,471]	[0,0]	-9	hSpCas9	positive selection	3366870
67376521	67376544	14	-	26780180	HT29	viability (Avana library 4 designs)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	6.62419352349315	[]	[]	9	hSpCas9	negative selection	3422215
67364974	67364997	14	+	26780180	HT29	viability (Avana library 4 designs)	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	6.22363236703758	[]	[]	9	hSpCas9	negative selection	3422216
67376465	67376488	14	+	26780180	HT29	viability (Avana library 4 designs)	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	5.09230648576955	[]	[]	9	hSpCas9	negative selection	3422217
67364791	67364814	14	+	26780180	HT29	viability (Avana library 4 designs)	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	5.78100079252329	[]	[]	9	hSpCas9	negative selection	3422218
67376521	67376544	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-22.3221423953554	[]	[]	-9	hSpCas9	negative selection	3502760
67364791	67364814	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	-20.776066882838	[]	[]	-9	hSpCas9	negative selection	3502761
67376465	67376488	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-12.6276199539183	[]	[]	-8	hSpCas9	negative selection	3502762
67364974	67364997	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-13.8441411954772	[]	[]	-8	hSpCas9	negative selection	3502763
67364844	67364867	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAAGCCCCCATTTCAGCAATGG	EIF2S1	ENSG00000134001	-5.29502706336267	[]	[]	-5	hSpCas9	negative selection	3502764
67364946	67364969	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAACTCATCCGAATTGGCAGG	EIF2S1	ENSG00000134001	-5.16839121036176	[]	[]	-5	hSpCas9	negative selection	3502765
67376521	67376544	14	-	26780180	A375	viability (Avana lentiGuide)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	34.2523198889696	[]	[]	9	hSpCas9	negative selection	3611419
67364791	67364814	14	+	26780180	A375	viability (Avana lentiGuide)	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	18.5651981161539	[]	[]	8	hSpCas9	negative selection	3611420
67376465	67376488	14	+	26780180	A375	viability (Avana lentiGuide)	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	25.6553699914582	[]	[]	9	hSpCas9	negative selection	3611421
67364974	67364997	14	+	26780180	A375	viability (Avana lentiGuide)	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	21.2612962289787	[]	[]	9	hSpCas9	negative selection	3611422
67364844	67364867	14	-	26780180	A375	viability (Avana lentiGuide)	ATAAGCCCCCATTTCAGCAATGG	EIF2S1	ENSG00000134001	21.6419020871075	[]	[]	9	hSpCas9	negative selection	3611423
67364946	67364969	14	+	26780180	A375	viability (Avana lentiGuide)	ACAAACTCATCCGAATTGGCAGG	EIF2S1	ENSG00000134001	18.9527304124003	[]	[]	8	hSpCas9	negative selection	3611424
67376521	67376544	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.7418013673630015	[6]	[0,0]	-9	hSpCas9	positive selection	3720078
67364791	67364814	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	-1.3777732897619883	[6]	[1,2]	-9	hSpCas9	positive selection	3720079
67376465	67376488	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-1.5026177234142035	[6]	[1,1]	-9	hSpCas9	positive selection	3720080
67364974	67364997	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-0.7155110561004829	[5]	[4,1]	-8	hSpCas9	positive selection	3720081
67364844	67364867	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAAGCCCCCATTTCAGCAATGG	EIF2S1	ENSG00000134001	-0.35169388792239165	[5]	[3,3]	-5	hSpCas9	positive selection	3720082
67364946	67364969	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAACTCATCCGAATTGGCAGG	EIF2S1	ENSG00000134001	-0.5502945199949524	[5]	[4,2]	-7	hSpCas9	positive selection	3720083
67376521	67376544	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.3546597330657557	[6]	[0,3]	-9	hSpCas9	positive selection	3828685
67364791	67364814	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATCAACACAAATTTCCTGAGG	EIF2S1	ENSG00000134001	-2.14644533801827	[5]	[0,0]	-9	hSpCas9	positive selection	3828686
67376465	67376488	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-2.3028426122848535	[4]	[0,0]	-9	hSpCas9	positive selection	3828687
67364974	67364997	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-0.5064442436325786	[6]	[4,2]	-6	hSpCas9	positive selection	3828688
67364844	67364867	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAAGCCCCCATTTCAGCAATGG	EIF2S1	ENSG00000134001	-0.7500845137490977	[5]	[2,2]	-7	hSpCas9	positive selection	3828689
67364946	67364969	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAACTCATCCGAATTGGCAGG	EIF2S1	ENSG00000134001	-1.0186379116623763	[6]	[3,0]	-8	hSpCas9	positive selection	3828690
67380744	67380767	14	+	26780180	A375	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	1.51452611438324	[]	[]	8	hSpCas9	negative selection	3936090
67376447	67376470	14	+	26780180	A375	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	1.47098481133275	[]	[]	8	hSpCas9	negative selection	3936091
67380653	67380676	14	+	26780180	A375	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.730607282207749	[]	[]	2	hSpCas9	negative selection	3936092
67381634	67381657	14	+	26780180	A375	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	1.48768186890451	[]	[]	8	hSpCas9	negative selection	3936093
67376521	67376544	14	-	26780180	A375	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	2.35149139816601	[]	[]	9	hSpCas9	negative selection	3936094
67381669	67381692	14	+	26780180	A375	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.331457583040228	[]	[]	0	hSpCas9	negative selection	3936095
67380744	67380767	14	+	26780180	HT29	viability (GeCKOv2 library)	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	2.01953805474739	[]	[]	9	hSpCas9	negative selection	4044056
67376447	67376470	14	+	26780180	HT29	viability (GeCKOv2 library)	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	1.94371851209901	[]	[]	9	hSpCas9	negative selection	4044057
67380653	67380676	14	+	26780180	HT29	viability (GeCKOv2 library)	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	1.048217533528	[]	[]	5	hSpCas9	negative selection	4044058
67381634	67381657	14	+	26780180	HT29	viability (GeCKOv2 library)	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	2.55640510618522	[]	[]	9	hSpCas9	negative selection	4044059
67376521	67376544	14	-	26780180	HT29	viability (GeCKOv2 library)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	2.93096193021606	[]	[]	9	hSpCas9	negative selection	4044060
67381669	67381692	14	+	26780180	HT29	viability (GeCKOv2 library)	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.473317428370742	[]	[]	1	hSpCas9	negative selection	4044061
67374484	67374507	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAAAGAAGAGTTTCTCCAGAGG	EIF2S1	ENSG00000134001	-0.3498196066972947	[1]	[0,0]	-7	hSpCas9	positive selection	4134245
67376447	67376470	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.49731912005226847	[3]	[1,1]	-8	hSpCas9	positive selection	4134246
67376521	67376544	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-0.26812920608580804	[1]	[0,0]	-6	hSpCas9	positive selection	4134247
67374500	67374523	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACATTTGATTGCTTCCTCTGG	EIF2S1	ENSG00000134001	0.1322816039534715	[3]	[2,2]	3	hSpCas9	positive selection	4134248
67374484	67374507	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAAAGAAGAGTTTCTCCAGAGG	EIF2S1	ENSG00000134001	0.9569876249489748	[0]	[0,0,0,0]	6	hSpCas9	positive selection	4198267
67376447	67376470	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.08392208626323772	[3]	[3,0,0,0]	-1	hSpCas9	positive selection	4198268
67376521	67376544	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-0.677102235015188	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4198269
67374500	67374523	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACATTTGATTGCTTCCTCTGG	EIF2S1	ENSG00000134001	0.2807617419268981	[3]	[1,1,3,0]	2	hSpCas9	positive selection	4198270
67380744	67380767	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.5947069771388385	[2]	[1,0]	-8	hSpCas9	positive selection	4268442
67376447	67376470	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.5817498584959467	[2]	[1,0]	-8	hSpCas9	positive selection	4268443
67376521	67376544	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.2945807304292396	[3]	[0,0]	-9	hSpCas9	positive selection	4268444
67381634	67381657	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.1785424920819414	[2]	[0,0]	-9	hSpCas9	positive selection	4332708
67380653	67380676	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.14382459618905202	[3]	[3,2]	3	hSpCas9	positive selection	4332709
67381669	67381692	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.3030714555407389	[4]	[4,3]	6	hSpCas9	positive selection	4332710
67364943	67364965	14	+	27760321	OCIAML3	viability	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-1.7097191937219873	[281,218]	[55,63]	-8	hSpCas9	negative selection	4397165
67376495	67376517	14	+	27760321	OCIAML3	viability	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	0.390213669958289	[304,234]	[229,332]	5	hSpCas9	negative selection	4397166
67376521	67376543	14	-	27760321	OCIAML3	viability	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.6082652180973143	[363,332]	[71,111]	-8	hSpCas9	negative selection	4397167
67380726	67380748	14	+	27760321	OCIAML3	viability	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-1.8772655646446719	[836,693]	[153,172]	-9	hSpCas9	negative selection	4397168
67380741	67380763	14	-	27760321	OCIAML3	viability	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.5959884816396238	[759,697]	[769,980]	7	hSpCas9	negative selection	4397169
67364943	67364965	14	+	27760321	OCIAML2	viability	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-2.2067229479856865	[281,218]	[40,46]	-9	hSpCas9	negative selection	4480628
67376495	67376517	14	+	27760321	OCIAML2	viability	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	0.5095267719828463	[304,234]	[296,323]	7	hSpCas9	negative selection	4480629
67376521	67376543	14	-	27760321	OCIAML2	viability	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.4686724840257623	[363,332]	[21,88]	-9	hSpCas9	negative selection	4480630
67380726	67380748	14	+	27760321	OCIAML2	viability	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-2.0981414878807767	[836,693]	[143,143]	-9	hSpCas9	negative selection	4480631
67380741	67380763	14	-	27760321	OCIAML2	viability	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.5190436295510729	[759,697]	[752,965]	7	hSpCas9	negative selection	4480632
67364943	67364965	14	+	27760321	MV411	viability	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-1.4917295454532618	[281,218]	[17,118]	-7	hSpCas9	negative selection	4564091
67376495	67376517	14	+	27760321	MV411	viability	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-0.24757248152122813	[304,234]	[116,196]	-2	hSpCas9	negative selection	4564092
67376521	67376543	14	-	27760321	MV411	viability	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.5095424155518256	[363,332]	[5,91]	-9	hSpCas9	negative selection	4564093
67380726	67380748	14	+	27760321	MV411	viability	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-1.083108758820105	[836,693]	[228,249]	-6	hSpCas9	negative selection	4564094
67380741	67380763	14	-	27760321	MV411	viability	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.9299121405809153	[759,697]	[821,1057]	6	hSpCas9	negative selection	4564095
67364943	67364965	14	+	27760321	HL60	viability	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-1.1056720971498255	[281,218]	[41,149]	-8	hSpCas9	negative selection	4647554
67376495	67376517	14	+	27760321	HL60	viability	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	0.05453246127258282	[304,234]	[222,231]	0	hSpCas9	negative selection	4647555
67376521	67376543	14	-	27760321	HL60	viability	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.6660649460988437	[363,332]	[111,65]	-9	hSpCas9	negative selection	4647556
67380726	67380748	14	+	27760321	HL60	viability	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-2.5416615540306724	[836,693]	[120,91]	-9	hSpCas9	negative selection	4647557
67380741	67380763	14	-	27760321	HL60	viability	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.4005481001164929	[759,697]	[583,999]	5	hSpCas9	negative selection	4647558
67364943	67364965	14	+	27760321	HT1080	viability	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-3.874605572670297	[218,170]	[0,9]	-8	hSpCas9	negative selection	4731017
67376495	67376517	14	+	27760321	HT1080	viability	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-4.433139993799021	[234,183]	[0,6]	-8	hSpCas9	negative selection	4731018
67376521	67376543	14	-	27760321	HT1080	viability	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-6.884107530381864	[332,259]	[0,0]	-9	hSpCas9	negative selection	4731019
67380726	67380748	14	+	27760321	HT1080	viability	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-7.943705026013406	[693,541]	[0,0]	-9	hSpCas9	negative selection	4731020
67380741	67380763	14	-	27760321	HT1080	viability	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	1.3026367353891077	[697,544]	[668,546]	7	hSpCas9	negative selection	4731021
67364943	67364965	14	+	27760321	HT29	viability after 7 days	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-1.0998253579106092	[218,170]	[84,73,184]	-8	hSpCas9	negative selection	4814480
67376495	67376517	14	+	27760321	HT29	viability after 7 days	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	0.048575298576099324	[234,183]	[397,349,109]	0	hSpCas9	negative selection	4814481
67376521	67376543	14	-	27760321	HT29	viability after 7 days	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.1214002564076777	[332,259]	[26,9,212]	-9	hSpCas9	negative selection	4814482
67380726	67380748	14	+	27760321	HT29	viability after 7 days	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-2.2452442778519615	[693,541]	[140,197,159]	-9	hSpCas9	negative selection	4814483
67380741	67380763	14	-	27760321	HT29	viability after 7 days	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.28980700416034044	[697,544]	[1077,900,964]	4	hSpCas9	negative selection	4814484
67364943	67364965	14	+	27760321	HT29	viability after 25 days	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-7.799236519172081	[218,170]	[0,0,0]	-9	hSpCas9	negative selection	4897943
67376495	67376517	14	+	27760321	HT29	viability after 25 days	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-1.7322964156257903	[234,183]	[44,12,169]	-7	hSpCas9	negative selection	4897944
67376521	67376543	14	-	27760321	HT29	viability after 25 days	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-6.449998215118309	[332,259]	[8,0,0]	-9	hSpCas9	negative selection	4897945
67380726	67380748	14	+	27760321	HT29	viability after 25 days	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-5.498092245989318	[693,541]	[20,22,0]	-9	hSpCas9	negative selection	4897946
67380741	67380763	14	-	27760321	HT29	viability after 25 days	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.875433983013582	[697,544]	[1432,1300,1148]	8	hSpCas9	negative selection	4897947
67364943	67364965	14	+	27760321	HT29	viability after 22 days	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-7.8165551510313405	[218,170]	[0,0,0]	-9	hSpCas9	negative selection	4981406
67376495	67376517	14	+	27760321	HT29	viability after 22 days	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-1.7015341379944051	[234,183]	[65,47,109]	-8	hSpCas9	negative selection	4981407
67376521	67376543	14	-	27760321	HT29	viability after 22 days	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-8.421108427087647	[332,259]	[0,0,0]	-9	hSpCas9	negative selection	4981408
67380726	67380748	14	+	27760321	HT29	viability after 22 days	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-5.076197955298638	[693,541]	[5,30,26]	-9	hSpCas9	negative selection	4981409
67380741	67380763	14	-	27760321	HT29	viability after 22 days	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.6085564711007947	[697,544]	[845,1171,1276]	6	hSpCas9	negative selection	4981410
67364943	67364965	14	+	27760321	HT29	viability after 19 days	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-7.800715098608127	[218,170]	[0,0,0]	-9	hSpCas9	negative selection	5064869
67376495	67376517	14	+	27760321	HT29	viability after 19 days	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-1.306390746434672	[234,183]	[83,100,103]	-7	hSpCas9	negative selection	5064870
67376521	67376543	14	-	27760321	HT29	viability after 19 days	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-7.717946443356906	[332,259]	[2,0,0]	-9	hSpCas9	negative selection	5064871
67380726	67380748	14	+	27760321	HT29	viability after 19 days	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-9.464865870295977	[693,541]	[0,0,0]	-9	hSpCas9	negative selection	5064872
67380741	67380763	14	-	27760321	HT29	viability after 19 days	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.8285403999497534	[697,544]	[1453,1352,1008]	8	hSpCas9	negative selection	5064873
67364943	67364965	14	+	27760321	HT29	viability after 16 days	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-7.380915890020529	[218,170]	[1,0,0]	-9	hSpCas9	negative selection	5148332
67376495	67376517	14	+	27760321	HT29	viability after 16 days	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-1.4581355085051768	[234,183]	[95,45,115]	-8	hSpCas9	negative selection	5148333
67376521	67376543	14	-	27760321	HT29	viability after 16 days	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.4830014240098777	[332,259]	[21,1,64]	-9	hSpCas9	negative selection	5148334
67380726	67380748	14	+	27760321	HT29	viability after 16 days	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-4.7770497562926595	[693,541]	[34,8,32]	-9	hSpCas9	negative selection	5148335
67380741	67380763	14	-	27760321	HT29	viability after 16 days	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.5624436472861747	[697,544]	[1286,1066,749]	6	hSpCas9	negative selection	5148336
67364943	67364965	14	+	27760321	HT29	viability after 13 days	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-4.880749234543017	[218,170]	[13,0,7]	-9	hSpCas9	negative selection	5231795
67376495	67376517	14	+	27760321	HT29	viability after 13 days	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-2.0131638408582875	[234,183]	[49,75,54]	-8	hSpCas9	negative selection	5231796
67376521	67376543	14	-	27760321	HT29	viability after 13 days	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-6.571491492518728	[332,259]	[8,0,0]	-9	hSpCas9	negative selection	5231797
67380726	67380748	14	+	27760321	HT29	viability after 13 days	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-5.856371900791699	[693,541]	[21,0,13]	-9	hSpCas9	negative selection	5231798
67380741	67380763	14	-	27760321	HT29	viability after 13 days	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.6442476627319094	[697,544]	[838,1360,1177]	8	hSpCas9	negative selection	5231799
67364943	67364965	14	+	27760321	HT29	viability after 10 days	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-2.5292979798536552	[218,170]	[25,38,60]	-9	hSpCas9	negative selection	5315258
67376495	67376517	14	+	27760321	HT29	viability after 10 days	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	0.3125961045235776	[234,183]	[221,496,261]	4	hSpCas9	negative selection	5315259
67376521	67376543	14	-	27760321	HT29	viability after 10 days	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-8.108196536577172	[332,259]	[0,0,1]	-9	hSpCas9	negative selection	5315260
67380726	67380748	14	+	27760321	HT29	viability after 10 days	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-4.730510099058664	[693,541]	[24,26,34]	-9	hSpCas9	negative selection	5315261
67380741	67380763	14	-	27760321	HT29	viability after 10 days	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.5603380043568513	[697,544]	[882,1206,1339]	7	hSpCas9	negative selection	5315262
67364943	67364965	14	+	27760321	MOLM13	viability	TCAACAAACTCATCCGAATTGG	EIF2S1	ENSG00000134001	-6.586931784457294	[281,218]	[1,0]	-9	hSpCas9	negative selection	5398721
67376495	67376517	14	+	27760321	MOLM13	viability	GCTGGAAAGCCTATTCCAGAGG	EIF2S1	ENSG00000134001	-1.0448598653608223	[304,234]	[102,47]	-6	hSpCas9	negative selection	5398722
67376521	67376543	14	-	27760321	MOLM13	viability	TACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.44769886499718	[363,332]	[37,0]	-9	hSpCas9	negative selection	5398723
67380726	67380748	14	+	27760321	MOLM13	viability	AATAGGCGCTTGACCCCACAGG	EIF2S1	ENSG00000134001	-0.889992484244136	[836,693]	[318,157]	-5	hSpCas9	negative selection	5398724
67380741	67380763	14	-	27760321	MOLM13	viability	CTCGAATTTTGACAGCCTGTGG	EIF2S1	ENSG00000134001	0.35293420763911876	[759,697]	[784,303]	2	hSpCas9	negative selection	5398725
67360342	67360365	14	+	27661255	K562	viability	GAGCGAAGCGCACGCTGAGGAGG	EIF2S1	ENSG00000134001	-5.695298139997456	[271,245]	[3,3]	-9	dCas9-KRAB	negative selection	5476900
67380744	67380767	14	+	27260156	BXPC3	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.1352314057046038	[266]	[120,111,119,159]	-9	hSpCas9	negative selection	5540902
67376447	67376470	14	+	27260156	BXPC3	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.6404406429430747	[441]	[283,239,301,371]	-8	hSpCas9	negative selection	5540903
67376521	67376544	14	-	27260156	BXPC3	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.0211090096982853	[588]	[138,120,122,235]	-9	hSpCas9	negative selection	5540904
67381634	67381657	14	+	27260156	BXPC3	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.9478336723585044	[240]	[52,64,98,42]	-9	hSpCas9	negative selection	5605168
67380653	67380676	14	+	27260156	BXPC3	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.21841541092990147	[667]	[716,708,928,921]	5	hSpCas9	negative selection	5605169
67381669	67381692	14	+	27260156	BXPC3	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	-0.007675175564851644	[1130]	[1079,1083,1147,1431]	0	hSpCas9	negative selection	5605170
67380744	67380767	14	+	27260156	A673	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.4714354654855304	[266]	[217,212,218,275]	-8	hSpCas9	negative selection	5662153
67376447	67376470	14	+	27260156	A673	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.43417258072255976	[441]	[472,375,288,445]	-8	hSpCas9	negative selection	5662154
67376521	67376544	14	-	27260156	A673	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-0.8652726157399955	[588]	[428,380,304,445]	-9	hSpCas9	negative selection	5662155
67381634	67381657	14	+	27260156	A673	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.9883930772536544	[240]	[168,157,138,117]	-9	hSpCas9	negative selection	5726419
67380653	67380676	14	+	27260156	A673	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.1667199807141918	[667]	[1014,879,746,976]	4	hSpCas9	negative selection	5726420
67381669	67381692	14	+	27260156	A673	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	-0.024777760987961805	[1130]	[1520,1208,1253,1380]	0	hSpCas9	negative selection	5726421
67380744	67380767	14	+	27260156	A375	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.6805370711328702	[266]	[104,37,60,167]	-9	hSpCas9	negative selection	5783404
67376447	67376470	14	+	27260156	A375	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.9510748384013399	[441]	[258,353,271,201]	-8	hSpCas9	negative selection	5783405
67376521	67376544	14	-	27260156	A375	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.4358746782343323	[588]	[138,194,87,98]	-9	hSpCas9	negative selection	5783406
67381634	67381657	14	+	27260156	A375	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.7417491429480896	[240]	[32,125,35,139]	-9	hSpCas9	negative selection	5847670
67380653	67380676	14	+	27260156	A375	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.4727191574788495	[667]	[1076,1189,1069,1012]	7	hSpCas9	negative selection	5847671
67381669	67381692	14	+	27260156	A375	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.22401423482305116	[1130]	[1768,1619,1837,1014]	3	hSpCas9	negative selection	5847672
67380744	67380767	14	+	27260156	COLO741	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.7219707063382625	[266]	[152,219,239]	-9	hSpCas9	negative selection	5904655
67376447	67376470	14	+	27260156	COLO741	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.5651583857858196	[441]	[383,302,451]	-8	hSpCas9	negative selection	5904656
67376521	67376544	14	-	27260156	COLO741	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.5918591379745397	[588]	[127,128,117]	-9	hSpCas9	negative selection	5904657
67381634	67381657	14	+	27260156	COLO741	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.0760772297811967	[240]	[250,97,100]	-9	hSpCas9	negative selection	5968921
67380653	67380676	14	+	27260156	COLO741	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.0904692376275199	[667]	[840,890,980]	2	hSpCas9	negative selection	5968922
67381669	67381692	14	+	27260156	COLO741	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.05044205268461255	[1130]	[1598,1459,1439]	1	hSpCas9	negative selection	5968923
67380744	67380767	14	+	27260156	CAL120	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.3307411862238177	[266]	[202,133,70]	-9	hSpCas9	negative selection	6025906
67376447	67376470	14	+	27260156	CAL120	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.8791780370841977	[441]	[344,265,292]	-8	hSpCas9	negative selection	6025907
67376521	67376544	14	-	27260156	CAL120	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-4.155767391283579	[588]	[54,60,9]	-9	hSpCas9	negative selection	6025908
67381634	67381657	14	+	27260156	CAL120	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.21072717004187	[240]	[65,90,37]	-9	hSpCas9	negative selection	6090172
67380653	67380676	14	+	27260156	CAL120	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.31168123218801547	[667]	[1136,687,1280]	5	hSpCas9	negative selection	6090173
67381669	67381692	14	+	27260156	CAL120	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.008948325198474771	[1130]	[1503,1446,1311]	0	hSpCas9	negative selection	6090174
67380744	67380767	14	+	27260156	CADOES1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.9265620062370152	[266]	[90,166,178,83]	-9	hSpCas9	negative selection	6147157
67376447	67376470	14	+	27260156	CADOES1	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.7393352230796669	[441]	[169,358,169,287]	-8	hSpCas9	negative selection	6147158
67376521	67376544	14	-	27260156	CADOES1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.816761417143172	[588]	[109,226,110,174]	-9	hSpCas9	negative selection	6147159
67381634	67381657	14	+	27260156	CADOES1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.1512825512325329	[240]	[88,120,136,54]	-9	hSpCas9	negative selection	6211423
67380653	67380676	14	+	27260156	CADOES1	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.4107882117606638	[667]	[1032,604,857,805]	6	hSpCas9	negative selection	6211424
67381669	67381692	14	+	27260156	CADOES1	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.2615019071692204	[1130]	[1214,1524,1105,1195]	4	hSpCas9	negative selection	6211425
67380744	67380767	14	+	27260156	EWS502	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.1669577263093307	[266]	[165,116,61,154]	-9	hSpCas9	negative selection	6268408
67376447	67376470	14	+	27260156	EWS502	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.64527029795552	[441]	[75,157,138,239]	-9	hSpCas9	negative selection	6268409
67376521	67376544	14	-	27260156	EWS502	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.6832269851196817	[588]	[82,127,69,107]	-9	hSpCas9	negative selection	6268410
67381634	67381657	14	+	27260156	EWS502	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.341733300554269	[240]	[49,56,25,68]	-9	hSpCas9	negative selection	6332674
67380653	67380676	14	+	27260156	EWS502	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.29784120234806777	[667]	[963,741,890,872]	5	hSpCas9	negative selection	6332675
67381669	67381692	14	+	27260156	EWS502	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.11180621423719583	[1130]	[1128,1386,1207,1476]	2	hSpCas9	negative selection	6332676
67380744	67380767	14	+	27260156	EW8	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.9742018367098315	[266]	[111,90,129,103]	-9	hSpCas9	negative selection	6389659
67376447	67376470	14	+	27260156	EW8	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.8955672028462593	[441]	[251,136,161,229]	-9	hSpCas9	negative selection	6389660
67376521	67376544	14	-	27260156	EW8	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.0500232353957353	[588]	[125,116,138,75]	-9	hSpCas9	negative selection	6389661
67381634	67381657	14	+	27260156	EW8	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.46802012810533156	[240]	[185,78,122,183]	-7	hSpCas9	negative selection	6453925
67380653	67380676	14	+	27260156	EW8	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	-0.21641518746186356	[667]	[475,566,347,492]	-4	hSpCas9	negative selection	6453926
67381669	67381692	14	+	27260156	EW8	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.19799046993941327	[1130]	[1158,972,853,1260]	3	hSpCas9	negative selection	6453927
67380744	67380767	14	+	27260156	CORL105	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.878730826509295	[266]	[128,216,184,148]	-9	hSpCas9	negative selection	6510910
67376447	67376470	14	+	27260156	CORL105	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.0329205514408035	[441]	[223,210,227,343]	-9	hSpCas9	negative selection	6510911
67376521	67376544	14	-	27260156	CORL105	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.3109598734923265	[588]	[291,316,230,263]	-9	hSpCas9	negative selection	6510912
67381634	67381657	14	+	27260156	CORL105	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.5875091640453112	[240]	[86,103,105,79]	-9	hSpCas9	negative selection	6575176
67380653	67380676	14	+	27260156	CORL105	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.15432221751405728	[667]	[733,839,1181,769]	3	hSpCas9	negative selection	6575177
67381669	67381692	14	+	27260156	CORL105	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	-0.1494133994568383	[1130]	[1101,1254,1279,1146]	-3	hSpCas9	negative selection	6575178
67380744	67380767	14	+	27260156	HS294T	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.620167407438984	[266]	[26,16,44,48]	-9	hSpCas9	negative selection	6632161
67376447	67376470	14	+	27260156	HS294T	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.7420149725845463	[441]	[43,102,119,155]	-8	hSpCas9	negative selection	6632162
67376521	67376544	14	-	27260156	HS294T	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.618618791629289	[588]	[29,18,65,33]	-9	hSpCas9	negative selection	6632163
67381634	67381657	14	+	27260156	HS294T	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.4064763232412094	[240]	[17,10,20,20]	-9	hSpCas9	negative selection	6696427
67380653	67380676	14	+	27260156	HS294T	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.5379657801416211	[667]	[533,246,309,400]	7	hSpCas9	negative selection	6696428
67381669	67381692	14	+	27260156	HS294T	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.11434201695148571	[1130]	[433,458,535,465]	1	hSpCas9	negative selection	6696429
67380744	67380767	14	+	27260156	HCC44	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.1786940159021912	[266]	[55,205,155,101]	-9	hSpCas9	negative selection	6753412
67376447	67376470	14	+	27260156	HCC44	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.0455986221933735	[441]	[374,193,337,99]	-8	hSpCas9	negative selection	6753413
67376521	67376544	14	-	27260156	HCC44	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.127764023416066	[588]	[118,66,440,43]	-9	hSpCas9	negative selection	6753414
67381634	67381657	14	+	27260156	HCC44	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.4711614176293795	[240]	[74,38,46,38]	-9	hSpCas9	negative selection	6817678
67380653	67380676	14	+	27260156	HCC44	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.2537323448909492	[667]	[957,877,994,792]	4	hSpCas9	negative selection	6817679
67381669	67381692	14	+	27260156	HCC44	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.2518075334030605	[1130]	[1668,1405,2043,1094]	4	hSpCas9	negative selection	6817680
67380744	67380767	14	+	27260156	G402	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.7000773032580905	[266]	[208,423,117,70]	-7	hSpCas9	negative selection	6874663
67376447	67376470	14	+	27260156	G402	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.3783541066861595	[441]	[541,482,232,421]	-5	hSpCas9	negative selection	6874664
67376521	67376544	14	-	27260156	G402	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.0731973787234694	[588]	[17,106,84,120]	-9	hSpCas9	negative selection	6874665
67381634	67381657	14	+	27260156	G402	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.0477261732523573	[240]	[33,6,32,194]	-9	hSpCas9	negative selection	6938929
67380653	67380676	14	+	27260156	G402	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.38992633681437405	[667]	[1557,1439,582,792]	5	hSpCas9	negative selection	6938930
67381669	67381692	14	+	27260156	G402	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.4892496758775935	[1130]	[3730,1540,1461,1275]	6	hSpCas9	negative selection	6938931
67380744	67380767	14	+	27260156	L33	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	0.03402618772388366	[266]	[226,143,139,292]	0	hSpCas9	negative selection	6995914
67376447	67376470	14	+	27260156	L33	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.05878415108493194	[441]	[338,189,332,367]	-1	hSpCas9	negative selection	6995915
67376521	67376544	14	-	27260156	L33	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.1219385231297716	[588]	[179,63,67,95]	-9	hSpCas9	negative selection	6995916
67381634	67381657	14	+	27260156	L33	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.2607699252073965	[240]	[109,32,50,129]	-9	hSpCas9	negative selection	7060180
67380653	67380676	14	+	27260156	L33	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	-0.11762304642326199	[667]	[658,245,347,647]	-3	hSpCas9	negative selection	7060181
67381669	67381692	14	+	27260156	L33	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.06084808467395919	[1130]	[1203,449,695,1306]	1	hSpCas9	negative selection	7060182
67380744	67380767	14	+	27260156	K562	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.6869512552445978	[266]	[90,71,73,59]	-9	hSpCas9	negative selection	7117165
67376447	67376470	14	+	27260156	K562	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.9790282719877781	[441]	[187,26,425,149]	-8	hSpCas9	negative selection	7117166
67376521	67376544	14	-	27260156	K562	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.57444390668819	[588]	[7,52,40,67]	-9	hSpCas9	negative selection	7117167
67381634	67381657	14	+	27260156	K562	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.9353615117582337	[240]	[141,39,70,183]	-8	hSpCas9	negative selection	7181431
67380653	67380676	14	+	27260156	K562	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.3550898025950403	[667]	[982,953,736,423]	4	hSpCas9	negative selection	7181432
67381669	67381692	14	+	27260156	K562	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.058095284627645016	[1130]	[1233,1239,974,782]	0	hSpCas9	negative selection	7181433
67380744	67380767	14	+	27260156	HT29	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.46428720590969	[266]	[86,141,190,56]	-9	hSpCas9	negative selection	7238416
67376447	67376470	14	+	27260156	HT29	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.8985222111653157	[441]	[360,273,346,185]	-8	hSpCas9	negative selection	7238417
67376521	67376544	14	-	27260156	HT29	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.5387983720622525	[588]	[228,70,75,119]	-9	hSpCas9	negative selection	7238418
67381634	67381657	14	+	27260156	HT29	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.868019179568475	[240]	[41,71,34,16]	-9	hSpCas9	negative selection	7302682
67380653	67380676	14	+	27260156	HT29	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.1033035504670976	[667]	[837,951,913,792]	2	hSpCas9	negative selection	7302683
67381669	67381692	14	+	27260156	HT29	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.0058525151763137995	[1130]	[1391,1333,1342,1432]	0	hSpCas9	negative selection	7302684
67380744	67380767	14	+	27260156	MHHES1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.9972923243987766	[266]	[231,127,134,118]	-9	hSpCas9	negative selection	7359667
67376447	67376470	14	+	27260156	MHHES1	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.8081574824283502	[441]	[302,292,366,192]	-9	hSpCas9	negative selection	7359668
67376521	67376544	14	-	27260156	MHHES1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.0017084346280798	[588]	[188,394,355,359]	-9	hSpCas9	negative selection	7359669
67381634	67381657	14	+	27260156	MHHES1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.1822767870853952	[240]	[43,78,199,135]	-9	hSpCas9	negative selection	7423933
67380653	67380676	14	+	27260156	MHHES1	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.2912012178983384	[667]	[895,1216,777,819]	5	hSpCas9	negative selection	7423934
67381669	67381692	14	+	27260156	MHHES1	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.1732796463292634	[1130]	[1394,1492,1689,1193]	3	hSpCas9	negative selection	7423935
67380744	67380767	14	+	27260156	MEWO	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.7814356357245873	[266]	[201,130,113]	-9	hSpCas9	negative selection	7480918
67376447	67376470	14	+	27260156	MEWO	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.5236305276045468	[441]	[269,178,410]	-8	hSpCas9	negative selection	7480919
67376521	67376544	14	-	27260156	MEWO	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.755832289367986	[588]	[205,113,177]	-9	hSpCas9	negative selection	7480920
67381634	67381657	14	+	27260156	MEWO	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.5847387667247184	[240]	[108,83,38]	-9	hSpCas9	negative selection	7545184
67380653	67380676	14	+	27260156	MEWO	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.1179200955990568	[667]	[702,719,615]	2	hSpCas9	negative selection	7545185
67381669	67381692	14	+	27260156	MEWO	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.9726982267474451	[1130]	[4899,1102,777]	9	hSpCas9	negative selection	7545186
67380744	67380767	14	+	27260156	LNCAPCLONEFGC	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.4192861352305972	[266]	[134,110,73,36]	-9	hSpCas9	negative selection	7602169
67376447	67376470	14	+	27260156	LNCAPCLONEFGC	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.810383349794315	[441]	[226,243,220,218]	-8	hSpCas9	negative selection	7602170
67376521	67376544	14	-	27260156	LNCAPCLONEFGC	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.7617643255744457	[588]	[179,118,208,130]	-9	hSpCas9	negative selection	7602171
67381634	67381657	14	+	27260156	LNCAPCLONEFGC	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.5317680983627298	[240]	[94,66,87,53]	-9	hSpCas9	negative selection	7666435
67380653	67380676	14	+	27260156	LNCAPCLONEFGC	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.46678871170792346	[667]	[844,619,898,1003]	7	hSpCas9	negative selection	7666436
67381669	67381692	14	+	27260156	LNCAPCLONEFGC	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.3094850033963561	[1130]	[1308,1028,1458,1323]	5	hSpCas9	negative selection	7666437
67380744	67380767	14	+	27260156	PANC0327	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.9774056283991279	[266]	[288,55,118,39]	-8	hSpCas9	negative selection	7723420
67376447	67376470	14	+	27260156	PANC0327	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.9208862828384035	[441]	[221,86,154,381]	-8	hSpCas9	negative selection	7723421
67376521	67376544	14	-	27260156	PANC0327	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.6080120769493895	[588]	[72,35,42,22]	-9	hSpCas9	negative selection	7723422
67381634	67381657	14	+	27260156	PANC0327	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-3.4830022981674666	[240]	[14,20,18,20]	-9	hSpCas9	negative selection	7787686
67380653	67380676	14	+	27260156	PANC0327	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.12306835272116512	[667]	[873,657,632,436]	1	hSpCas9	negative selection	7787687
67381669	67381692	14	+	27260156	PANC0327	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.3956514752152891	[1130]	[1596,1214,1409,1100]	6	hSpCas9	negative selection	7787688
67380744	67380767	14	+	27260156	NCIH2009	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.362810402230738	[266]	[142,116,174]	-8	hSpCas9	negative selection	7844671
67376447	67376470	14	+	27260156	NCIH2009	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.857784123941975	[441]	[170,223,114]	-9	hSpCas9	negative selection	7844672
67376521	67376544	14	-	27260156	NCIH2009	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.235228833172959	[588]	[81,139,37]	-9	hSpCas9	negative selection	7844673
67381634	67381657	14	+	27260156	NCIH2009	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.532018395332562	[240]	[97,25,58]	-9	hSpCas9	negative selection	7908937
67380653	67380676	14	+	27260156	NCIH2009	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.5922175259480096	[667]	[1591,1307,1356]	7	hSpCas9	negative selection	7908938
67381669	67381692	14	+	27260156	NCIH2009	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.02274623069783166	[1130]	[2005,1404,1484]	0	hSpCas9	negative selection	7908939
67380744	67380767	14	+	27260156	NCIH1373	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.05022870931974	[266]	[290,64,129,31]	-8	hSpCas9	negative selection	7965922
67376447	67376470	14	+	27260156	NCIH1373	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.8148510842463865	[441]	[178,167,57,42]	-9	hSpCas9	negative selection	7965923
67376521	67376544	14	-	27260156	NCIH1373	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.5780724042304968	[588]	[328,31,14,28]	-9	hSpCas9	negative selection	7965924
67381634	67381657	14	+	27260156	NCIH1373	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.8722778424811388	[240]	[92,5,142,15]	-9	hSpCas9	negative selection	8030188
67380653	67380676	14	+	27260156	NCIH1373	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.960666041751363	[667]	[1339,1644,1159,434]	8	hSpCas9	negative selection	8030189
67381669	67381692	14	+	27260156	NCIH1373	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.21182663904935617	[1130]	[1247,1407,1398,473]	2	hSpCas9	negative selection	8030190
67380744	67380767	14	+	27260156	PATU8902	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-4.150237573472996	[266]	[51,2,2,30]	-9	hSpCas9	negative selection	8087173
67376447	67376470	14	+	27260156	PATU8902	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.8780129946013417	[441]	[193,410,132,696]	-7	hSpCas9	negative selection	8087174
67376521	67376544	14	-	27260156	PATU8902	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-7.055216551187747	[588]	[5,3,5,8]	-9	hSpCas9	negative selection	8087175
67381634	67381657	14	+	27260156	PATU8902	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-7.09113208627708	[240]	[4,2,0,0]	-9	hSpCas9	negative selection	8151439
67380653	67380676	14	+	27260156	PATU8902	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.35223580769295315	[667]	[1208,764,976,1931]	3	hSpCas9	negative selection	8151440
67381669	67381692	14	+	27260156	PATU8902	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.2689519122452957	[1130]	[2223,1922,1500,2044]	2	hSpCas9	negative selection	8151441
67380744	67380767	14	+	27260156	PANC1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.8598810833341755	[266]	[180,115,98,106]	-8	hSpCas9	negative selection	8208424
67376447	67376470	14	+	27260156	PANC1	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.8231812348424437	[441]	[43,198,93,109]	-9	hSpCas9	negative selection	8208425
67376521	67376544	14	-	27260156	PANC1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.630417003212006	[588]	[27,67,67,9]	-9	hSpCas9	negative selection	8208426
67381634	67381657	14	+	27260156	PANC1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.7313708425592598	[240]	[9,35,69,12]	-9	hSpCas9	negative selection	8272690
67380653	67380676	14	+	27260156	PANC1	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.25671370449035624	[667]	[580,984,580,651]	4	hSpCas9	negative selection	8272691
67381669	67381692	14	+	27260156	PANC1	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.23003633732156548	[1130]	[1304,1696,873,823]	3	hSpCas9	negative selection	8272692
67380744	67380767	14	+	27260156	PANC0813	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.303253993355202	[266]	[171,43,142,151]	-9	hSpCas9	negative selection	8329675
67376447	67376470	14	+	27260156	PANC0813	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.3062177135832294	[441]	[274,173,179,215]	-9	hSpCas9	negative selection	8329676
67376521	67376544	14	-	27260156	PANC0813	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.4816403365440016	[588]	[114,109,152,116]	-9	hSpCas9	negative selection	8329677
67381634	67381657	14	+	27260156	PANC0813	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.752944571813918	[240]	[140,49,116,35]	-9	hSpCas9	negative selection	8393941
67380653	67380676	14	+	27260156	PANC0813	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.31465933326022444	[667]	[1029,1033,996,852]	5	hSpCas9	negative selection	8393942
67381669	67381692	14	+	27260156	PANC0813	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.08852072229697683	[1130]	[1467,1298,1619,1274]	1	hSpCas9	negative selection	8393943
67380744	67380767	14	+	27260156	RDES	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.6764677639526437	[266]	[81,117,74,107]	-9	hSpCas9	negative selection	8450926
67376447	67376470	14	+	27260156	RDES	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.9459748911739876	[441]	[228,252,233,351]	-9	hSpCas9	negative selection	8450927
67376521	67376544	14	-	27260156	RDES	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.5397535358829724	[588]	[93,156,88,122]	-9	hSpCas9	negative selection	8450928
67381634	67381657	14	+	27260156	RDES	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.2717227203974726	[240]	[70,77,120,214]	-9	hSpCas9	negative selection	8515192
67380653	67380676	14	+	27260156	RDES	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.3957288559751252	[667]	[701,1032,1061,1332]	6	hSpCas9	negative selection	8515193
67381669	67381692	14	+	27260156	RDES	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.26415908882101147	[1130]	[1293,1547,1567,1900]	4	hSpCas9	negative selection	8515194
67380744	67380767	14	+	27260156	PC3	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.7528036159631291	[266]	[66,183,146,260]	-9	hSpCas9	negative selection	8572177
67376447	67376470	14	+	27260156	PC3	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.3403299056972129	[441]	[220,405,625,260]	-6	hSpCas9	negative selection	8572178
67376521	67376544	14	-	27260156	PC3	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.3036810506058727	[588]	[87,205,548,284]	-9	hSpCas9	negative selection	8572179
67381634	67381657	14	+	27260156	PC3	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.6162963982575624	[240]	[152,181,168,101]	-8	hSpCas9	negative selection	8636443
67380653	67380676	14	+	27260156	PC3	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.07710583358065115	[667]	[537,694,797,809]	1	hSpCas9	negative selection	8636444
67381669	67381692	14	+	27260156	PC3	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	-0.02265247823011185	[1130]	[627,1018,1828,1372]	0	hSpCas9	negative selection	8636445
67380744	67380767	14	+	27260156	PATU8988T	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.3232454165717058	[266]	[68,176,87,83]	-9	hSpCas9	negative selection	8693428
67376447	67376470	14	+	27260156	PATU8988T	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.9310071601157353	[441]	[130,271,143,365]	-8	hSpCas9	negative selection	8693429
67376521	67376544	14	-	27260156	PATU8988T	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.089142759192823	[588]	[65,81,64,54]	-9	hSpCas9	negative selection	8693430
67381634	67381657	14	+	27260156	PATU8988T	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.642051771658646	[240]	[92,17,64,120]	-9	hSpCas9	negative selection	8757694
67380653	67380676	14	+	27260156	PATU8988T	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.2833230713164223	[667]	[794,719,719,911]	5	hSpCas9	negative selection	8757695
67381669	67381692	14	+	27260156	PATU8988T	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.20873642787615032	[1130]	[1001,1248,1383,1426]	3	hSpCas9	negative selection	8757696
67380744	67380767	14	+	27260156	T47D	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.28437273290757803	[266]	[238,224,249,311]	-6	hSpCas9	negative selection	8814679
67376447	67376470	14	+	27260156	T47D	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.3838460375993968	[441]	[409,373,363,433]	-7	hSpCas9	negative selection	8814680
67376521	67376544	14	-	27260156	T47D	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.8077980184245688	[588]	[164,212,148,257]	-9	hSpCas9	negative selection	8814681
67381634	67381657	14	+	27260156	T47D	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.7421803300190679	[240]	[138,187,201,138]	-9	hSpCas9	negative selection	8878945
67380653	67380676	14	+	27260156	T47D	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.10878451761014363	[667]	[857,722,840,947]	2	hSpCas9	negative selection	8878946
67381669	67381692	14	+	27260156	T47D	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.0932243553399521	[1130]	[1421,1230,1358,1632]	2	hSpCas9	negative selection	8878947
67380744	67380767	14	+	27260156	SU8686	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.8409363144578432	[266]	[78,91,41,78]	-9	hSpCas9	negative selection	8935930
67376447	67376470	14	+	27260156	SU8686	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-1.5355717019606026	[441]	[132,144,128,207]	-9	hSpCas9	negative selection	8935931
67376521	67376544	14	-	27260156	SU8686	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.543031962517338	[588]	[84,118,95,98]	-9	hSpCas9	negative selection	8935932
67381634	67381657	14	+	27260156	SU8686	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.529245077264166	[240]	[49,27,53,32]	-9	hSpCas9	negative selection	9000196
67380653	67380676	14	+	27260156	SU8686	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.1806892069860463	[667]	[745,604,733,965]	3	hSpCas9	negative selection	9000197
67381669	67381692	14	+	27260156	SU8686	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.21683944870655592	[1130]	[1267,1139,1207,1668]	3	hSpCas9	negative selection	9000198
67380744	67380767	14	+	27260156	SKES1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.7158907369162368	[266]	[192,144,114,192]	-9	hSpCas9	negative selection	9057181
67376447	67376470	14	+	27260156	SKES1	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.5987717059428417	[441]	[304,249,216,376]	-8	hSpCas9	negative selection	9057182
67376521	67376544	14	-	27260156	SKES1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.4968186011223699	[588]	[278,261,147,163]	-9	hSpCas9	negative selection	9057183
67381634	67381657	14	+	27260156	SKES1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.4135394940891275	[240]	[195,219,103,204]	-7	hSpCas9	negative selection	9121447
67380653	67380676	14	+	27260156	SKES1	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.09111795269760903	[667]	[671,804,759,611]	2	hSpCas9	negative selection	9121448
67381669	67381692	14	+	27260156	SKES1	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.09377124421845862	[1130]	[1335,1197,1247,1055]	2	hSpCas9	negative selection	9121449
67380744	67380767	14	+	27260156	TOV112D	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.2904767984731771	[266]	[370,285,113,134]	-5	hSpCas9	negative selection	9178432
67376447	67376470	14	+	27260156	TOV112D	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	0.029269547547808396	[441]	[655,599,225,379]	0	hSpCas9	negative selection	9178433
67376521	67376544	14	-	27260156	TOV112D	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.0384232578880936	[588]	[335,357,156,317]	-9	hSpCas9	negative selection	9178434
67381634	67381657	14	+	27260156	TOV112D	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-1.6376789562323404	[240]	[86,67,126,27]	-9	hSpCas9	negative selection	9242698
67380653	67380676	14	+	27260156	TOV112D	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.13146124714124297	[667]	[1000,733,662,559]	2	hSpCas9	negative selection	9242699
67381669	67381692	14	+	27260156	TOV112D	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.13724152392954436	[1130]	[1583,1217,962,1237]	2	hSpCas9	negative selection	9242700
67380744	67380767	14	+	27260156	TC71	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.12486390233253553	[266]	[167,348,278,254]	-3	hSpCas9	negative selection	9299683
67376447	67376470	14	+	27260156	TC71	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.36801428863091873	[441]	[289,376,383,421]	-7	hSpCas9	negative selection	9299684
67376521	67376544	14	-	27260156	TC71	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-1.0977106574548883	[588]	[315,301,281,278]	-9	hSpCas9	negative selection	9299685
67381634	67381657	14	+	27260156	TC71	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.5959966278601974	[240]	[158,110,206,207]	-9	hSpCas9	negative selection	9363949
67380653	67380676	14	+	27260156	TC71	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	-0.005313806138457888	[667]	[682,759,765,638]	0	hSpCas9	negative selection	9363950
67381669	67381692	14	+	27260156	TC71	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	-0.08355495925775913	[1130]	[1186,1035,1210,1138]	-2	hSpCas9	negative selection	9363951
67380744	67380767	14	+	27260156	TC32	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.6216167139079611	[266]	[182,137,204,127]	-8	hSpCas9	negative selection	9420934
67376447	67376470	14	+	27260156	TC32	viability	CATTCTTCGTCATGTTGCTGAGG	EIF2S1	ENSG00000134001	-0.5101314888970059	[441]	[282,123,423,414]	-7	hSpCas9	negative selection	9420935
67376521	67376544	14	-	27260156	TC32	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-0.8316205906400658	[588]	[225,221,421,426]	-9	hSpCas9	negative selection	9420936
67381634	67381657	14	+	27260156	TC32	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-0.4368676142100769	[240]	[157,198,128,152]	-7	hSpCas9	negative selection	9485200
67380653	67380676	14	+	27260156	TC32	viability	GACCAGAGACCCATCTATTTTGG	EIF2S1	ENSG00000134001	0.2613088102621638	[667]	[789,553,1088,653]	4	hSpCas9	negative selection	9485201
67381669	67381692	14	+	27260156	TC32	viability	TACAGAAAACATGCCCATTAAGG	EIF2S1	ENSG00000134001	0.12497841167527834	[1130]	[1085,976,1289,1320]	2	hSpCas9	negative selection	9485202
67376532	67376555	14	+	27869803	HPAFII	viability after 27 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-5.498684300326395	[85]	[0,0,NaN]	-9	hSpCas9	negative selection	9552085
67382473	67382496	14	+	27869803	HPAFII	viability after 27 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.168362755730099	[348]	[84,3,NaN]	-8	hSpCas9	negative selection	9552086
67383341	67383364	14	+	27869803	HPAFII	viability after 27 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-2.9188742873708415	[84]	[0,9,NaN]	-9	hSpCas9	negative selection	9552087
67376532	67376555	14	+	27869803	HPAFII	viability after 15 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-4.6490656129561225	[85]	[7,0,NaN]	-9	hSpCas9	negative selection	9634534
67382473	67382496	14	+	27869803	HPAFII	viability after 15 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.629332199142674	[348]	[96,37,NaN]	-9	hSpCas9	negative selection	9634535
67383341	67383364	14	+	27869803	HPAFII	viability after 15 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-1.7242406139483804	[84]	[10,37,NaN]	-9	hSpCas9	negative selection	9634536
67376532	67376555	14	+	27869803	ASPC1	viability after 36 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-1.5350909330522495	[193]	[0,70,0]	-8	hSpCas9	negative selection	9716983
67382473	67382496	14	+	27869803	ASPC1	viability after 36 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-4.579794237356336	[967]	[13,17,10]	-9	hSpCas9	negative selection	9716984
67383341	67383364	14	+	27869803	ASPC1	viability after 36 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-3.6126363211720154	[174]	[13,1,0]	-9	hSpCas9	negative selection	9716985
67376532	67376555	14	+	27869803	PATU8988S	viability after 35 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-5.907125744388347	[148]	[0,0,NaN]	-9	hSpCas9	negative selection	9799432
67382473	67382496	14	+	27869803	PATU8988S	viability after 35 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.665451535967829	[754]	[16,78,NaN]	-9	hSpCas9	negative selection	9799433
67383341	67383364	14	+	27869803	PATU8988S	viability after 35 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	0.1185054207710019	[159]	[50,88,NaN]	1	hSpCas9	negative selection	9799434
67376532	67376555	14	+	27869803	PATU8988S	viability after 31 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-5.892701329012159	[148]	[0,0,NaN]	-9	hSpCas9	negative selection	9881881
67382473	67382496	14	+	27869803	PATU8988S	viability after 31 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-2.724095125983393	[754]	[56,30,NaN]	-9	hSpCas9	negative selection	9881882
67383341	67383364	14	+	27869803	PATU8988S	viability after 31 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-0.1022109731419476	[159]	[36,87,NaN]	-1	hSpCas9	negative selection	9881883
67376532	67376555	14	+	27869803	HPAFII	viability after 35 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-5.444176201705424	[85]	[0,0,NaN]	-9	hSpCas9	negative selection	9964330
67382473	67382496	14	+	27869803	HPAFII	viability after 35 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.588938841551717	[348]	[109,0,NaN]	-7	hSpCas9	negative selection	9964331
67383341	67383364	14	+	27869803	HPAFII	viability after 35 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-5.427302383141027	[84]	[0,0,NaN]	-9	hSpCas9	negative selection	9964332
67376532	67376555	14	+	27869803	HPAFII	viability after 31 days	GATGACAAGTACAAGAGACCTGG	EIF2S1	ENSG00000134001	-5.592893555026841	[85]	[0,0,NaN]	-9	hSpCas9	negative selection	10046779
67382473	67382496	14	+	27869803	HPAFII	viability after 31 days	TGTAATGACTACGACAACCCTGG	EIF2S1	ENSG00000134001	-1.7915281815465656	[348]	[102,5,NaN]	-7	hSpCas9	negative selection	10046780
67383341	67383364	14	+	27869803	HPAFII	viability after 31 days	GACTGAACTTGCGAGGCAGATGG	EIF2S1	ENSG00000134001	-2.723735471504396	[84]	[0,13,NaN]	-8	hSpCas9	negative selection	10046781
67382462	67382485	14	-	28162770	P31FUJ	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.8632793643879038	[160]	[12]	-9	hSpCas9	negative selection	10148932
67376521	67376544	14	-	28162770	P31FUJ	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.5948077386770763	[729]	[70]	-9	hSpCas9	negative selection	10148933
67376465	67376488	14	+	28162770	P31FUJ	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-2.884878900994072	[219]	[34]	-9	hSpCas9	negative selection	10148934
67381634	67381657	14	+	28162770	P31FUJ	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-3.661645503218253	[139]	[12]	-9	hSpCas9	negative selection	10148935
67382546	67382569	14	+	28162770	P31FUJ	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-5.647839703693222	[127]	[2]	-9	hSpCas9	negative selection	10148936
67364809	67364832	14	+	28162770	P31FUJ	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.255170017442833	[324]	[39]	-9	hSpCas9	negative selection	10148937
67364974	67364997	14	+	28162770	P31FUJ	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-2.4443063096080904	[87]	[18]	-8	hSpCas9	negative selection	10148938
67382518	67382541	14	-	28162770	P31FUJ	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-3.028661487634153	[124]	[17]	-9	hSpCas9	negative selection	10148939
67380744	67380767	14	+	28162770	P31FUJ	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.4119710501003109	[136]	[120]	-4	hSpCas9	negative selection	10148940
67382486	67382509	14	+	28162770	P31FUJ	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-2.2038231374426127	[344]	[87]	-8	hSpCas9	negative selection	10148941
67382462	67382485	14	-	28162770	TF1	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10318298
67376521	67376544	14	-	28162770	TF1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10318299
67376465	67376488	14	+	28162770	TF1	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10318300
67381634	67381657	14	+	28162770	TF1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10318301
67382546	67382569	14	+	28162770	TF1	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10318302
67364809	67364832	14	+	28162770	TF1	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10318303
67364974	67364997	14	+	28162770	TF1	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10318304
67382518	67382541	14	-	28162770	TF1	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10318305
67380744	67380767	14	+	28162770	TF1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10318306
67382486	67382509	14	+	28162770	TF1	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10318307
67382462	67382485	14	-	28162770	SKM1	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.6964708159381465	[43]	[5]	-9	hSpCas9	negative selection	10487664
67376521	67376544	14	-	28162770	SKM1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-5.354496778849026	[161]	[6]	-9	hSpCas9	negative selection	10487665
67376465	67376488	14	+	28162770	SKM1	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-3.991926699464318	[71]	[7]	-9	hSpCas9	negative selection	10487666
67381634	67381657	14	+	28162770	SKM1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-5.576889200185474	[26]	[0]	-9	hSpCas9	negative selection	10487667
67382546	67382569	14	+	28162770	SKM1	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-6.436711542137213	[48]	[0]	-9	hSpCas9	negative selection	10487668
67364809	67364832	14	+	28162770	SKM1	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.1294302232142526	[98]	[19]	-9	hSpCas9	negative selection	10487669
67364974	67364997	14	+	28162770	SKM1	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-2.587536444384983	[16]	[4]	-9	hSpCas9	negative selection	10487670
67382518	67382541	14	-	28162770	SKM1	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-2.5224414161630975	[38]	[11]	-9	hSpCas9	negative selection	10487671
67380744	67380767	14	+	28162770	SKM1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.5224414161630975	[25]	[31]	-4	hSpCas9	negative selection	10487672
67382486	67382509	14	+	28162770	SKM1	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-4.050820388517886	[74]	[7]	-9	hSpCas9	negative selection	10487673
67382462	67382485	14	-	28162770	SKM1	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.6964708159381465	[43]	[5]	-9	hSpCas9	negative selection	10657030
67376521	67376544	14	-	28162770	SKM1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-5.354496778849026	[161]	[6]	-9	hSpCas9	negative selection	10657031
67376465	67376488	14	+	28162770	SKM1	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-3.991926699464318	[71]	[7]	-9	hSpCas9	negative selection	10657032
67381634	67381657	14	+	28162770	SKM1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-5.576889200185474	[26]	[0]	-9	hSpCas9	negative selection	10657033
67382546	67382569	14	+	28162770	SKM1	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-6.436711542137213	[48]	[0]	-9	hSpCas9	negative selection	10657034
67364809	67364832	14	+	28162770	SKM1	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.1294302232142526	[98]	[19]	-9	hSpCas9	negative selection	10657035
67364974	67364997	14	+	28162770	SKM1	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-2.587536444384983	[16]	[4]	-9	hSpCas9	negative selection	10657036
67382518	67382541	14	-	28162770	SKM1	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-2.5224414161630975	[38]	[11]	-9	hSpCas9	negative selection	10657037
67380744	67380767	14	+	28162770	SKM1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.5224414161630975	[25]	[31]	-4	hSpCas9	negative selection	10657038
67382486	67382509	14	+	28162770	SKM1	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-4.050820388517886	[74]	[7]	-9	hSpCas9	negative selection	10657039
67382462	67382485	14	-	28162770	PL21	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.2674659355936773	[176]	[7]	-9	hSpCas9	negative selection	10826396
67376521	67376544	14	-	28162770	PL21	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.204076391536009	[486]	[22]	-9	hSpCas9	negative selection	10826397
67376465	67376488	14	+	28162770	PL21	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-3.887323226761019	[237]	[6]	-9	hSpCas9	negative selection	10826398
67381634	67381657	14	+	28162770	PL21	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.2962862116301785	[78]	[6]	-8	hSpCas9	negative selection	10826399
67382546	67382569	14	+	28162770	PL21	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-5.74237489084992	[122]	[0]	-9	hSpCas9	negative selection	10826400
67364809	67364832	14	+	28162770	PL21	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.121788480398042	[379]	[18]	-9	hSpCas9	negative selection	10826401
67364974	67364997	14	+	28162770	PL21	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-3.1921778082894408	[41]	[1]	-9	hSpCas9	negative selection	10826402
67382518	67382541	14	-	28162770	PL21	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	1.4158683055447574	[92]	[107]	9	hSpCas9	negative selection	10826403
67380744	67380767	14	+	28162770	PL21	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-2.1217884803980422	[99]	[9]	-8	hSpCas9	negative selection	10826404
67382486	67382509	14	+	28162770	PL21	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-2.1354634172951186	[211]	[20]	-8	hSpCas9	negative selection	10826405
67382462	67382485	14	-	28162770	P31FUJ	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.8632793643879038	[160]	[12]	-9	hSpCas9	negative selection	10995762
67376521	67376544	14	-	28162770	P31FUJ	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.5948077386770763	[729]	[70]	-9	hSpCas9	negative selection	10995763
67376465	67376488	14	+	28162770	P31FUJ	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-2.884878900994072	[219]	[34]	-9	hSpCas9	negative selection	10995764
67381634	67381657	14	+	28162770	P31FUJ	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-3.661645503218253	[139]	[12]	-9	hSpCas9	negative selection	10995765
67382546	67382569	14	+	28162770	P31FUJ	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-5.647839703693222	[127]	[2]	-9	hSpCas9	negative selection	10995766
67364809	67364832	14	+	28162770	P31FUJ	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.255170017442833	[324]	[39]	-9	hSpCas9	negative selection	10995767
67364974	67364997	14	+	28162770	P31FUJ	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-2.4443063096080904	[87]	[18]	-8	hSpCas9	negative selection	10995768
67382518	67382541	14	-	28162770	P31FUJ	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-3.028661487634153	[124]	[17]	-9	hSpCas9	negative selection	10995769
67380744	67380767	14	+	28162770	P31FUJ	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.4119710501003109	[136]	[120]	-4	hSpCas9	negative selection	10995770
67382486	67382509	14	+	28162770	P31FUJ	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-2.2038231374426127	[344]	[87]	-8	hSpCas9	negative selection	10995771
67382462	67382485	14	-	28162770	OCIAML5	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.9675437882839333	[77]	[8]	-9	hSpCas9	negative selection	11165128
67376521	67376544	14	-	28162770	OCIAML5	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-6.973081971825363	[347]	[4]	-9	hSpCas9	negative selection	11165129
67376465	67376488	14	+	28162770	OCIAML5	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-3.6696898283754282	[140]	[19]	-9	hSpCas9	negative selection	11165130
67381634	67381657	14	+	28162770	OCIAML5	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-5.579987025427196	[52]	[1]	-9	hSpCas9	negative selection	11165131
67382546	67382569	14	+	28162770	OCIAML5	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-6.91815576132177	[66]	[0]	-9	hSpCas9	negative selection	11165132
67364809	67364832	14	+	28162770	OCIAML5	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-1.0860237438333673	[166]	[141]	-6	hSpCas9	negative selection	11165133
67364974	67364997	14	+	28162770	OCIAML5	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-5.0379331161753305	[90]	[4]	-9	hSpCas9	negative selection	11165134
67382518	67382541	14	-	28162770	OCIAML5	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-1.9086500992303643	[51]	[24]	-7	hSpCas9	negative selection	11165135
67380744	67380767	14	+	28162770	OCIAML5	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.3170292954745233	[97]	[70]	-6	hSpCas9	negative selection	11165136
67382486	67382509	14	+	28162770	OCIAML5	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-3.2065993311832868	[178]	[34]	-9	hSpCas9	negative selection	11165137
67382462	67382485	14	-	28162770	EOL1	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.9424500969144716	[320]	[10]	-9	hSpCas9	negative selection	11334494
67376521	67376544	14	-	28162770	EOL1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-5.406369106544083	[643]	[7]	-9	hSpCas9	negative selection	11334495
67376465	67376488	14	+	28162770	EOL1	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-5.501716983131563	[429]	[4]	-9	hSpCas9	negative selection	11334496
67381634	67381657	14	+	28162770	EOL1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-3.223350923541779	[194]	[10]	-9	hSpCas9	negative selection	11334497
67382546	67382569	14	+	28162770	EOL1	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-4.183976685207634	[275]	[7]	-9	hSpCas9	negative selection	11334498
67364809	67364832	14	+	28162770	EOL1	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-1.2886554783112532	[625]	[134]	-7	hSpCas9	negative selection	11334499
67364974	67364997	14	+	28162770	EOL1	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-1.9749253524755008	[96]	[12]	-8	hSpCas9	negative selection	11334500
67382518	67382541	14	-	28162770	EOL1	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-4.493304743315363	[170]	[3]	-9	hSpCas9	negative selection	11334501
67380744	67380767	14	+	28162770	EOL1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.539399328189256	[159]	[28]	-7	hSpCas9	negative selection	11334502
67382486	67382509	14	+	28162770	EOL1	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-1.4691160769157423	[267]	[50]	-7	hSpCas9	negative selection	11334503
67382462	67382485	14	-	28162770	MOLM13	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.3855619551024794	[317]	[21]	-8	hSpCas9	negative selection	11503860
67376521	67376544	14	-	28162770	MOLM13	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.6433131807750314	[673]	[38]	-9	hSpCas9	negative selection	11503861
67376465	67376488	14	+	28162770	MOLM13	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-3.715907794479291	[417]	[22]	-9	hSpCas9	negative selection	11503862
67381634	67381657	14	+	28162770	MOLM13	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-5.671661970854215	[140]	[1]	-9	hSpCas9	negative selection	11503863
67382546	67382569	14	+	28162770	MOLM13	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-7.300294943232348	[217]	[0]	-9	hSpCas9	negative selection	11503864
67364809	67364832	14	+	28162770	MOLM13	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-7.506525208260949	[502]	[1]	-9	hSpCas9	negative selection	11503865
67364974	67364997	14	+	28162770	MOLM13	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-5.013237308192037	[133]	[2]	-9	hSpCas9	negative selection	11503866
67382518	67382541	14	-	28162770	MOLM13	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-4.839539143647668	[197]	[4]	-9	hSpCas9	negative selection	11503867
67380744	67380767	14	+	28162770	MOLM13	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-2.4526761509610164	[158]	[20]	-8	hSpCas9	negative selection	11503868
67382486	67382509	14	+	28162770	MOLM13	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-3.8358913666325245	[394]	[19]	-9	hSpCas9	negative selection	11503869
67382462	67382485	14	-	28162770	HEL	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-4.989529383499155	[247]	[4]	-9	hSpCas9	negative selection	11673226
67376521	67376544	14	-	28162770	HEL	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-4.841696792766835	[581]	[12]	-9	hSpCas9	negative selection	11673227
67376465	67376488	14	+	28162770	HEL	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-2.0055496040896283	[325]	[51]	-8	hSpCas9	negative selection	11673228
67381634	67381657	14	+	28162770	HEL	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-5.758140604281827	[168]	[1]	-9	hSpCas9	negative selection	11673229
67382546	67382569	14	+	28162770	HEL	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-6.705989322230721	[162]	[0]	-9	hSpCas9	negative selection	11673230
67364809	67364832	14	+	28162770	HEL	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.9280098095010985	[403]	[16]	-9	hSpCas9	negative selection	11673231
67364974	67364997	14	+	28162770	HEL	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-5.9118500196772805	[93]	[0]	-9	hSpCas9	negative selection	11673232
67382518	67382541	14	-	28162770	HEL	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-3.5271861694419555	[107]	[5]	-9	hSpCas9	negative selection	11673233
67380744	67380767	14	+	28162770	HEL	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-1.555674726401651	[178]	[38]	-7	hSpCas9	negative selection	11673234
67382486	67382509	14	+	28162770	HEL	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-3.66711643058643	[356]	[17]	-9	hSpCas9	negative selection	11673235
67382462	67382485	14	-	28162770	MV411	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-2.499796378837258	[187]	[27]	-8	hSpCas9	negative selection	11842592
67376521	67376544	14	-	28162770	MV411	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-3.7772245034514933	[471]	[28]	-9	hSpCas9	negative selection	11842593
67376465	67376488	14	+	28162770	MV411	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-3.0875466969300334	[221]	[21]	-9	hSpCas9	negative selection	11842594
67381634	67381657	14	+	28162770	MV411	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-3.4668079668833474	[104]	[7]	-9	hSpCas9	negative selection	11842595
67382546	67382569	14	+	28162770	MV411	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-5.585452463381967	[113]	[1]	-9	hSpCas9	negative selection	11842596
67364809	67364832	14	+	28162770	MV411	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-1.2451609317897212	[362]	[128]	-7	hSpCas9	negative selection	11842597
67364974	67364997	14	+	28162770	MV411	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-4.03054719651699	[96]	[4]	-9	hSpCas9	negative selection	11842598
67382518	67382541	14	-	28162770	MV411	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-3.525151953114152	[122]	[8]	-9	hSpCas9	negative selection	11842599
67380744	67380767	14	+	28162770	MV411	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	1.3900419462255755	[76]	[169]	9	hSpCas9	negative selection	11842600
67382486	67382509	14	+	28162770	MV411	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-1.4750284736883157	[230]	[69]	-7	hSpCas9	negative selection	11842601
67382462	67382485	14	-	28162770	MONOMAC1	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-4.181929954669346	[94]	[5]	-9	hSpCas9	negative selection	12011958
67376521	67376544	14	-	28162770	MONOMAC1	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-4.406490212688504	[295]	[15]	-9	hSpCas9	negative selection	12011959
67376465	67376488	14	+	28162770	MONOMAC1	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-1.6857840325214066	[173]	[61]	-8	hSpCas9	negative selection	12011960
67381634	67381657	14	+	28162770	MONOMAC1	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.2993985646892314	[72]	[16]	-9	hSpCas9	negative selection	12011961
67382546	67382569	14	+	28162770	MONOMAC1	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-3.071505964975695	[87]	[11]	-9	hSpCas9	negative selection	12011962
67364809	67364832	14	+	28162770	MONOMAC1	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-2.0498108938763755	[241]	[66]	-9	hSpCas9	negative selection	12011963
67364974	67364997	14	+	28162770	MONOMAC1	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-1.5063649051672825	[56]	[22]	-8	hSpCas9	negative selection	12011964
67382518	67382541	14	-	28162770	MONOMAC1	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-0.6868421147403699	[65]	[46]	-5	hSpCas9	negative selection	12011965
67380744	67380767	14	+	28162770	MONOMAC1	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	0.28449606400619687	[52]	[73]	3	hSpCas9	negative selection	12011966
67382486	67382509	14	+	28162770	MONOMAC1	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-2.0099512944590585	[129]	[36]	-8	hSpCas9	negative selection	12011967
67382462	67382485	14	-	28162770	OCIAML2	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-3.470629825242161	[29]	[14]	-9	hSpCas9	negative selection	12181324
67376521	67376544	14	-	28162770	OCIAML2	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-5.821127072326294	[101]	[9]	-9	hSpCas9	negative selection	12181325
67376465	67376488	14	+	28162770	OCIAML2	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-2.554694090030636	[52]	[49]	-8	hSpCas9	negative selection	12181326
67381634	67381657	14	+	28162770	OCIAML2	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-4.409229280578018	[22]	[5]	-9	hSpCas9	negative selection	12181327
67382546	67382569	14	+	28162770	OCIAML2	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-7.37752042085068	[29]	[0]	-9	hSpCas9	negative selection	12181328
67364809	67364832	14	+	28162770	OCIAML2	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-3.2887915022563483	[66]	[37]	-9	hSpCas9	negative selection	12181329
67364974	67364997	14	+	28162770	OCIAML2	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-5.0555923259633175	[23]	[3]	-9	hSpCas9	negative selection	12181330
67382518	67382541	14	-	28162770	OCIAML2	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-2.885667324521005	[19]	[14]	-9	hSpCas9	negative selection	12181331
67380744	67380767	14	+	28162770	OCIAML2	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	-0.1032587595936319	[24]	[128]	-1	hSpCas9	negative selection	12181332
67382486	67382509	14	+	28162770	OCIAML2	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-1.970200834732673	[40]	[57]	-8	hSpCas9	negative selection	12181333
67382462	67382485	14	-	28162770	OCIAML3	viability	GTAGTCATTACATACCGAGGAGG	EIF2S1	ENSG00000134001	-2.0731754770227226	[45]	[32]	-8	hSpCas9	negative selection	12350690
67376521	67376544	14	-	28162770	OCIAML3	viability	GTACTTGTCATCAAAGACCCAGG	EIF2S1	ENSG00000134001	-2.8445511019747602	[137]	[57]	-9	hSpCas9	negative selection	12350691
67376465	67376488	14	+	28162770	OCIAML3	viability	TGAGGTGTTAGAATACACCAAGG	EIF2S1	ENSG00000134001	-1.8350157398279578	[51]	[43]	-8	hSpCas9	negative selection	12350692
67381634	67381657	14	+	28162770	OCIAML3	viability	GTAAAAGAAGCCCTAAGAGCAGG	EIF2S1	ENSG00000134001	-2.6529013293777317	[24]	[11]	-9	hSpCas9	negative selection	12350693
67382546	67382569	14	+	28162770	OCIAML3	viability	GAGAAGATTGAGGAAAAGAGGGG	EIF2S1	ENSG00000134001	-3.0887723320737406	[30]	[10]	-9	hSpCas9	negative selection	12350694
67364809	67364832	14	+	28162770	OCIAML3	viability	TGAGGTGGAAGATGTAGTGATGG	EIF2S1	ENSG00000134001	-2.1789701410453195	[125]	[83]	-8	hSpCas9	negative selection	12350695
67364974	67364997	14	+	28162770	OCIAML3	viability	GTGTGTGGTTGTCATTAGGGTGG	EIF2S1	ENSG00000134001	-1.342468873328199	[20]	[24]	-7	hSpCas9	negative selection	12350696
67382518	67382541	14	-	28162770	OCIAML3	viability	TAACAGCCATAGCTTGACTGAGG	EIF2S1	ENSG00000134001	-3.0534392589614603	[32]	[11]	-9	hSpCas9	negative selection	12350697
67380744	67380767	14	+	28162770	OCIAML3	viability	CAGGCTGTCAAAATTCGAGCAGG	EIF2S1	ENSG00000134001	0.6812703612643778	[43]	[212]	6	hSpCas9	negative selection	12350698
67382486	67382509	14	+	28162770	OCIAML3	viability	ACAACCCTGGAGAGAACAGAAGG	EIF2S1	ENSG00000134001	-0.35631608260483255	[66]	[157]	-3	hSpCas9	negative selection	12350699