Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2050
• Symbol:EPHB4
• Description:EPH receptor B4

DataSource: http://genomecrispr.dkfz.de/#!/results/EPHB4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
100823812	100823835	7	-	26472758	Jiyoye	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.5126542698101432	[139]	[73]	-4	hSpCas9	negative selection	51010
100807570	100807593	7	-	26472758	Jiyoye	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	1.933244193173461	[24]	[71]	8	hSpCas9	negative selection	51011
100822270	100822293	7	-	26472758	Jiyoye	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	1.7482122993409406	[14]	[37]	8	hSpCas9	negative selection	51012
100822649	100822672	7	-	26472758	Jiyoye	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	-0.966283014021571	[170]	[65]	-6	hSpCas9	negative selection	51013
100820140	100820163	7	+	26472758	Jiyoye	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.8457483952455063	[75]	[102]	6	hSpCas9	negative selection	51014
100819867	100819890	7	+	26472758	Jiyoye	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	2.8077133110896018	[24]	[131]	9	hSpCas9	negative selection	51015
100819836	100819859	7	+	26472758	Jiyoye	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	-0.6197916660943958	[215]	[105]	-4	hSpCas9	negative selection	51016
100819556	100819579	7	-	26472758	Jiyoye	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.13683044499242492	[190]	[130]	-1	hSpCas9	negative selection	51017
100812910	100812933	7	-	26472758	Jiyoye	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.5033906967651766	[86]	[92]	4	hSpCas9	negative selection	51018
100812735	100812758	7	+	26472758	Jiyoye	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	1.5491943863783013	[28]	[63]	8	hSpCas9	negative selection	51019
100823812	100823835	7	-	26472758	KBM7	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	0.35532631618882354	[452,224]	[284,119]	4	hSpCas9	negative selection	242128
100807570	100807593	7	-	26472758	KBM7	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-1.0035344943607611	[393,371]	[108,72]	-6	hSpCas9	negative selection	242129
100822270	100822293	7	-	26472758	KBM7	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	1.0345091865285196	[103,72]	[43,119]	9	hSpCas9	negative selection	242130
100822649	100822672	7	-	26472758	KBM7	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	1.1024141729480286	[530,235]	[499,260]	9	hSpCas9	negative selection	242131
100820140	100820163	7	+	26472758	KBM7	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.7962588660101768	[438,290]	[230,348]	8	hSpCas9	negative selection	242132
100819867	100819890	7	+	26472758	KBM7	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	0.1971787331187772	[231,337]	[179,136]	2	hSpCas9	negative selection	242133
100819836	100819859	7	+	26472758	KBM7	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.5693838840236898	[350,339]	[310,179]	6	hSpCas9	negative selection	242134
100819556	100819579	7	-	26472758	KBM7	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.036069572614059686	[585,569]	[286,272]	0	hSpCas9	negative selection	242135
100812910	100812933	7	-	26472758	KBM7	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	-0.22645266947944925	[387,299]	[134,138]	-2	hSpCas9	negative selection	242136
100812735	100812758	7	+	26472758	KBM7	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.1171587476818654	[225,119]	[87,83]	1	hSpCas9	negative selection	242137
100823812	100823835	7	-	26472758	Raji	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	0.5036844720708574	[154]	[50]	5	hSpCas9	negative selection	433246
100807570	100807593	7	-	26472758	Raji	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.7787485000681218	[206]	[27]	-5	hSpCas9	negative selection	433247
100822270	100822293	7	-	26472758	Raji	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-0.9706189766276738	[75]	[8]	-6	hSpCas9	negative selection	433248
100822649	100822672	7	-	26472758	Raji	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	1.3026398267725332	[137]	[78]	9	hSpCas9	negative selection	433249
100820140	100820163	7	+	26472758	Raji	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	1.4751153198740865	[154]	[99]	9	hSpCas9	negative selection	433250
100819867	100819890	7	+	26472758	Raji	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	0.8062140006530344	[137]	[55]	7	hSpCas9	negative selection	433251
100819836	100819859	7	+	26472758	Raji	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.6373568014971033	[204]	[73]	6	hSpCas9	negative selection	433252
100819556	100819579	7	-	26472758	Raji	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.7642389545765412	[273]	[107]	7	hSpCas9	negative selection	433253
100812910	100812933	7	-	26472758	Raji	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.4511623514826214	[248]	[78]	4	hSpCas9	negative selection	433254
100812735	100812758	7	+	26472758	Raji	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.13775718441711837	[93]	[23]	1	hSpCas9	negative selection	433255
100823812	100823835	7	-	26472758	K562	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.875875506051265	[199]	[91]	-5	hSpCas9	negative selection	624364
100807570	100807593	7	-	26472758	K562	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.570438525602988	[240]	[136]	-4	hSpCas9	negative selection	624365
100822270	100822293	7	-	26472758	K562	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-0.893084796083488	[54]	[24]	-5	hSpCas9	negative selection	624366
100822649	100822672	7	-	26472758	K562	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	1.4857113543461744	[194]	[460]	9	hSpCas9	negative selection	624367
100820140	100820163	7	+	26472758	K562	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.9839582654964796	[223]	[373]	8	hSpCas9	negative selection	624368
100819867	100819890	7	+	26472758	K562	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	0.035832105855029384	[259]	[224]	0	hSpCas9	negative selection	624369
100819836	100819859	7	+	26472758	K562	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.24441872766644682	[402]	[402]	1	hSpCas9	negative selection	624370
100819556	100819579	7	-	26472758	K562	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.3376262896724151	[493]	[329]	-2	hSpCas9	negative selection	624371
100812910	100812933	7	-	26472758	K562	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.14750058439066727	[353]	[330]	1	hSpCas9	negative selection	624372
100812735	100812758	7	+	26472758	K562	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	1.5620338296827265	[66]	[166]	9	hSpCas9	negative selection	624373
100818600	100818623	7	+	26627737	DLD1	viability	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.11566516056241602	[488]	[166,200,68]	-1	hSpCas9	negative selection	834185
100819556	100819579	7	-	26627737	DLD1	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.14913837722901713	[870]	[282,247,210]	-1	hSpCas9	negative selection	834186
100822353	100822376	7	+	26627737	DLD1	viability	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	-0.20350616478030892	[191]	[25,46,78]	-2	hSpCas9	negative selection	834187
100823682	100823705	7	-	26627737	DLD1	viability	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.1881292629386061	[564]	[140,249,212]	2	hSpCas9	negative selection	834188
100824202	100824225	7	-	26627737	DLD1	viability	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	0.4350565447385054	[227]	[53,122,110]	4	hSpCas9	negative selection	834189
100818600	100818623	7	+	26627737	GBM cells	viability after 5 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.17902179407842078	[153]	[113,72]	3	hSpCas9	negative selection	916500
100819556	100819579	7	-	26627737	GBM cells	viability after 5 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.6262555409932129	[448]	[153,157]	-7	hSpCas9	negative selection	916501
100822353	100822376	7	+	26627737	GBM cells	viability after 5 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.6821024858125373	[85]	[38,108]	8	hSpCas9	negative selection	916502
100823682	100823705	7	-	26627737	GBM cells	viability after 5 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.36346532920610686	[178]	[106,139]	5	hSpCas9	negative selection	916503
100824202	100824225	7	-	26627737	GBM cells	viability after 5 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.12910050128391104	[103]	[40,60]	-2	hSpCas9	negative selection	916504
100818600	100818623	7	+	26627737	GBM cells	viability after 13 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.05276269481304974	[153]	[116,61]	0	hSpCas9	negative selection	998815
100819556	100819579	7	-	26627737	GBM cells	viability after 13 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.7314686940144052	[448]	[154,139]	-7	hSpCas9	negative selection	998816
100822353	100822376	7	+	26627737	GBM cells	viability after 13 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	1.0393636469389638	[85]	[112,81]	9	hSpCas9	negative selection	998817
100823682	100823705	7	-	26627737	GBM cells	viability after 13 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.45683623248467925	[178]	[188,87]	6	hSpCas9	negative selection	998818
100824202	100824225	7	-	26627737	GBM cells	viability after 13 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.26465083840175163	[103]	[57,37]	-3	hSpCas9	negative selection	998819
100818600	100818623	7	+	26627737	GBM cells	viability after 21 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.07269620759242434	[153]	[99,76]	0	hSpCas9	negative selection	1081130
100819556	100819579	7	-	26627737	GBM cells	viability after 21 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-2.1825929022060397	[448]	[59,47]	-9	hSpCas9	negative selection	1081131
100822353	100822376	7	+	26627737	GBM cells	viability after 21 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	1.1633204558834136	[85]	[112,96]	9	hSpCas9	negative selection	1081132
100823682	100823705	7	-	26627737	GBM cells	viability after 21 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	-0.4922728944438908	[178]	[65,71]	-4	hSpCas9	negative selection	1081133
100824202	100824225	7	-	26627737	GBM cells	viability after 21 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.9839456200214525	[103]	[26,29]	-7	hSpCas9	negative selection	1081134
100818600	100818623	7	+	26627737	RPE1	viability after 9 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	1.0399560001281385	[469]	[202,430]	6	hSpCas9	negative selection	1163445
100819556	100819579	7	-	26627737	RPE1	viability after 9 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.6442497646792248	[1864]	[349,403]	-4	hSpCas9	negative selection	1163446
100822353	100822376	7	+	26627737	RPE1	viability after 9 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	1.1409556527128322	[430]	[235,376]	7	hSpCas9	negative selection	1163447
100823682	100823705	7	-	26627737	RPE1	viability after 9 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.12469950145417302	[651]	[277,150]	0	hSpCas9	negative selection	1163448
100824202	100824225	7	-	26627737	RPE1	viability after 9 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.34733209316741465	[302]	[105,33]	-2	hSpCas9	negative selection	1163449
100818600	100818623	7	+	26627737	RPE1	viability after 12 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.5469597599105211	[469]	[200,166]	3	hSpCas9	negative selection	1245760
100819556	100819579	7	-	26627737	RPE1	viability after 12 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.5643151309810627	[1864]	[384,289]	-4	hSpCas9	negative selection	1245761
100822353	100822376	7	+	26627737	RPE1	viability after 12 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	2.1001757490838853	[430]	[648,334]	9	hSpCas9	negative selection	1245762
100823682	100823705	7	-	26627737	RPE1	viability after 12 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.8869787943165203	[651]	[406,235]	5	hSpCas9	negative selection	1245763
100824202	100824225	7	-	26627737	RPE1	viability after 12 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.5134495834075192	[302]	[57,55]	-4	hSpCas9	negative selection	1245764
100818600	100818623	7	+	26627737	RPE1	viability after 15 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	1.5836350779047201	[469]	[623,180]	8	hSpCas9	negative selection	1328075
100819556	100819579	7	-	26627737	RPE1	viability after 15 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.4526747940544895	[1864]	[329,438]	-3	hSpCas9	negative selection	1328076
100822353	100822376	7	+	26627737	RPE1	viability after 15 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	2.8979570347105024	[430]	[1287,542]	9	hSpCas9	negative selection	1328077
100823682	100823705	7	-	26627737	RPE1	viability after 15 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.9497440180235048	[651]	[454,260]	5	hSpCas9	negative selection	1328078
100824202	100824225	7	-	26627737	RPE1	viability after 15 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.7781565623575042	[302]	[22,75]	-5	hSpCas9	negative selection	1328079
100818600	100818623	7	+	26627737	RPE1	viability after 18 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	1.1238541709268086	[469]	[375,169]	6	hSpCas9	negative selection	1410390
100819556	100819579	7	-	26627737	RPE1	viability after 18 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.6520180712436068	[1864]	[328,310]	-4	hSpCas9	negative selection	1410391
100822353	100822376	7	+	26627737	RPE1	viability after 18 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	3.071248455635195	[430]	[1082,864]	9	hSpCas9	negative selection	1410392
100823682	100823705	7	-	26627737	RPE1	viability after 18 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	-0.17787146443644514	[651]	[185,122]	-1	hSpCas9	negative selection	1410393
100824202	100824225	7	-	26627737	RPE1	viability after 18 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.3996402936964405	[302]	[46,77]	-3	hSpCas9	negative selection	1410394
100818600	100818623	7	+	26627737	HeLa	viability after 8 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.055670886900429595	[284]	[76,127,141]	0	hSpCas9	negative selection	1492705
100819556	100819579	7	-	26627737	HeLa	viability after 8 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.3886650283104182	[649]	[238,239,176]	-4	hSpCas9	negative selection	1492706
100822353	100822376	7	+	26627737	HeLa	viability after 8 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	3.463433908003789	[30]	[225,171,70]	9	hSpCas9	negative selection	1492707
100823682	100823705	7	-	26627737	HeLa	viability after 8 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	-0.2651362814817167	[608]	[249,300,123]	-3	hSpCas9	negative selection	1492708
100824202	100824225	7	-	26627737	HeLa	viability after 8 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.0625497751408108	[87]	[176,88,0]	7	hSpCas9	negative selection	1492709
100818600	100818623	7	+	26627737	HeLa	viability after 12 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.9498779327931142	[284]	[450,76,176]	7	hSpCas9	negative selection	1575020
100819556	100819579	7	-	26627737	HeLa	viability after 12 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.7234017492815438	[649]	[106,185,190]	-6	hSpCas9	negative selection	1575021
100822353	100822376	7	+	26627737	HeLa	viability after 12 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	3.4013501982198404	[30]	[153,112,141]	9	hSpCas9	negative selection	1575022
100823682	100823705	7	-	26627737	HeLa	viability after 12 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.10273755500632664	[608]	[260,189,367]	0	hSpCas9	negative selection	1575023
100824202	100824225	7	-	26627737	HeLa	viability after 12 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.6570256146677487	[87]	[142,141,56]	9	hSpCas9	negative selection	1575024
100818600	100818623	7	+	26627737	HeLa	viability after 15 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.8962722870206277	[284]	[134,187,334]	6	hSpCas9	negative selection	1657335
100819556	100819579	7	-	26627737	HeLa	viability after 15 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.5338241460695333	[649]	[221,152,171]	-5	hSpCas9	negative selection	1657336
100822353	100822376	7	+	26627737	HeLa	viability after 15 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	3.0186158781581462	[30]	[133,62,109]	9	hSpCas9	negative selection	1657337
100823682	100823705	7	-	26627737	HeLa	viability after 15 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.3304014192668314	[608]	[206,351,382]	2	hSpCas9	negative selection	1657338
100824202	100824225	7	-	26627737	HeLa	viability after 15 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.640316008453925	[87]	[146,94,90]	9	hSpCas9	negative selection	1657339
100818600	100818623	7	+	26627737	HeLa	viability after 18 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.8855315388467029	[284]	[87,154,334]	6	hSpCas9	negative selection	1739650
100819556	100819579	7	-	26627737	HeLa	viability after 18 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.5061134958721885	[649]	[149,133,171]	-4	hSpCas9	negative selection	1739651
100822353	100822376	7	+	26627737	HeLa	viability after 18 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	3.0022632928688124	[30]	[86,52,109]	9	hSpCas9	negative selection	1739652
100823682	100823705	7	-	26627737	HeLa	viability after 18 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.36132535361956164	[608]	[145,298,382]	3	hSpCas9	negative selection	1739653
100824202	100824225	7	-	26627737	HeLa	viability after 18 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.6798673870576788	[87]	[105,76,90]	9	hSpCas9	negative selection	1739654
100818600	100818623	7	+	26627737	HCT116	viability after 6 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.6751990436161928	[1193]	[152,97]	-4	hSpCas9	negative selection	1821965
100819556	100819579	7	-	26627737	HCT116	viability after 6 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	1.3945872239047339	[1031]	[626,315]	7	hSpCas9	negative selection	1821966
100822353	100822376	7	+	26627737	HCT116	viability after 6 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	-2.8262547056934606	[386]	[5,9]	-9	hSpCas9	negative selection	1821967
100823682	100823705	7	-	26627737	HCT116	viability after 6 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	1.2782428441882385	[482]	[392,68]	6	hSpCas9	negative selection	1821968
100824202	100824225	7	-	26627737	HCT116	viability after 6 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-1.7765609299310772	[153]	[8,5]	-7	hSpCas9	negative selection	1821969
100818600	100818623	7	+	26627737	HCT116	viability after 8 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.07143411946760864	[288]	[186,174,93]	0	hSpCas9	negative selection	1904280
100819556	100819579	7	-	26627737	HCT116	viability after 8 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.1512199882033438	[356]	[297,157,200]	1	hSpCas9	negative selection	1904281
100822353	100822376	7	+	26627737	HCT116	viability after 8 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.5865112093318232	[153]	[169,82,129]	6	hSpCas9	negative selection	1904282
100823682	100823705	7	-	26627737	HCT116	viability after 8 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	-0.17324339173458458	[321]	[129,136,203]	-2	hSpCas9	negative selection	1904283
100824202	100824225	7	-	26627737	HCT116	viability after 8 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	0.324872989101634	[95]	[88,28,80]	3	hSpCas9	negative selection	1904284
100818600	100818623	7	+	26627737	HCT116	viability after 9 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.7984847002144512	[1193]	[208,162]	-5	hSpCas9	negative selection	1986595
100819556	100819579	7	-	26627737	HCT116	viability after 9 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-1.1242202779751584	[1031]	[193,72]	-7	hSpCas9	negative selection	1986596
100822353	100822376	7	+	26627737	HCT116	viability after 9 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	-2.0970603071584866	[386]	[36,13]	-8	hSpCas9	negative selection	1986597
100823682	100823705	7	-	26627737	HCT116	viability after 9 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	-0.0714427141538681	[482]	[67,165]	0	hSpCas9	negative selection	1986598
100824202	100824225	7	-	26627737	HCT116	viability after 9 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	0.7264304536703026	[153]	[81,56]	5	hSpCas9	negative selection	1986599
100818600	100818623	7	+	26627737	HCT116	viability after 12 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.10165383914424642	[288]	[142,161,119]	-1	hSpCas9	negative selection	2068910
100819556	100819579	7	-	26627737	HCT116	viability after 12 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.6437289718600652	[356]	[321,217,334]	6	hSpCas9	negative selection	2068911
100822353	100822376	7	+	26627737	HCT116	viability after 12 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.3185091550319964	[153]	[61,92,150]	3	hSpCas9	negative selection	2068912
100823682	100823705	7	-	26627737	HCT116	viability after 12 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.37288273214821255	[321]	[285,197,166]	3	hSpCas9	negative selection	2068913
100824202	100824225	7	-	26627737	HCT116	viability after 12 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	0.0853937213792102	[95]	[4,59,99]	0	hSpCas9	negative selection	2068914
100818600	100818623	7	+	26627737	HCT116	viability after 15 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.05954449877512705	[288]	[240,192,54]	0	hSpCas9	negative selection	2151225
100819556	100819579	7	-	26627737	HCT116	viability after 15 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.1362245727589323	[356]	[375,149,168]	1	hSpCas9	negative selection	2151226
100822353	100822376	7	+	26627737	HCT116	viability after 15 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	1.0037693173152227	[153]	[171,66,290]	8	hSpCas9	negative selection	2151227
100823682	100823705	7	-	26627737	HCT116	viability after 15 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.02428477827582609	[321]	[362,160,62]	0	hSpCas9	negative selection	2151228
100824202	100824225	7	-	26627737	HCT116	viability after 15 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.3600678570827791	[95]	[59,32,37]	-4	hSpCas9	negative selection	2151229
100818600	100818623	7	+	26627737	HCT116	viability after 18 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.3466535206359439	[288]	[204,174,151]	3	hSpCas9	negative selection	2233540
100819556	100819579	7	-	26627737	HCT116	viability after 18 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.680835239368462	[356]	[463,259,98]	5	hSpCas9	negative selection	2233541
100822353	100822376	7	+	26627737	HCT116	viability after 18 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.9809539054031509	[153]	[133,13,308]	7	hSpCas9	negative selection	2233542
100823682	100823705	7	-	26627737	HCT116	viability after 18 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.597191794451381	[321]	[276,136,301]	5	hSpCas9	negative selection	2233543
100824202	100824225	7	-	26627737	HCT116	viability after 18 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-0.8406000235810207	[95]	[16,35,23]	-6	hSpCas9	negative selection	2233544
100824198	100824221	7	+	24336569	HL60	viability	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	0.9206096312803859	[868]	[3480]	7	hSpCas9	negative selection	2263016
100824206	100824229	7	-	24336569	HL60	viability	TGACATTCCCTCAGGTGGACGGG	EPHB4	ENSG00000196411	1.2363654260448453	[140]	[702]	8	hSpCas9	negative selection	2263017
100824211	100824234	7	-	24336569	HL60	viability	GTGGGTGACATTCCCTCAGGTGG	EPHB4	ENSG00000196411	1.8550773015178792	[60]	[466]	9	hSpCas9	negative selection	2263018
100824229	100824252	7	-	24336569	HL60	viability	GGAAACTGCTGATCTGAAGTGGG	EPHB4	ENSG00000196411	-0.14477246762989648	[1315]	[2518]	-1	hSpCas9	negative selection	2263019
100824198	100824221	7	+	24336569	KBM7	viability	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	1.2700084458305425	[771]	[5077]	9	hSpCas9	negative selection	2330193
100824206	100824229	7	-	24336569	KBM7	viability	TGACATTCCCTCAGGTGGACGGG	EPHB4	ENSG00000196411	0.26682424296523205	[347]	[1141]	2	hSpCas9	negative selection	2330194
100824211	100824234	7	-	24336569	KBM7	viability	GTGGGTGACATTCCCTCAGGTGG	EPHB4	ENSG00000196411	0.07539641727657265	[213]	[614]	0	hSpCas9	negative selection	2330195
100824229	100824252	7	-	24336569	KBM7	viability	GGAAACTGCTGATCTGAAGTGGG	EPHB4	ENSG00000196411	0.15891304709024712	[1041]	[3172]	1	hSpCas9	negative selection	2330196
100821293	100821316	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCTCCATGTTGGTCAGGCAGG	EPHB4	ENSG00000196411	-2.2958931667653815	[393,165]	[8,14]	-9	dCas9-VP64	positive selection	2417401
100822063	100822086	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGGAGAACTGCTTGAACAGG	EPHB4	ENSG00000196411	0.7070246765679	[33,152]	[9,58]	3	dCas9-VP64	positive selection	2454496
100821293	100821316	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCTCCATGTTGGTCAGGCAGG	EPHB4	ENSG00000196411	0.6223741115754664	[126,133]	[38,89]	4	dCas9-VP64	positive selection	2512656
100822063	100822086	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGGAGAACTGCTTGAACAGG	EPHB4	ENSG00000196411	0.5604147924363393	[108,122]	[76,35]	4	dCas9-VP64	positive selection	2549751
100822633	100822656	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	-0.3595356937343959	[3,3]	[2,1]	-5	hSpCas9	positive selection	2986089
100823771	100823794	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCATGGTGAAGCGCAGCGTGG	EPHB4	ENSG00000196411	-0.27487198910721816	[2,2]	[2,1]	-4	hSpCas9	positive selection	2986090
100822649	100822672	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	-0.7948277395434553	[2,2]	[0,1]	-8	hSpCas9	positive selection	2986091
100819600	100819623	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGTATCCTCCTTAGCCACGGGG	EPHB4	ENSG00000196411	0.3272039180017545	[3,4]	[4,4]	7	hSpCas9	positive selection	2986092
100822633	100822656	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	-0.234479460102561	[3,3]	[2,1]	-3	hSpCas9	positive selection	3053947
100823771	100823794	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCATGGTGAAGCGCAGCGTGG	EPHB4	ENSG00000196411	0.5532375882026193	[2,2]	[2,3]	8	hSpCas9	positive selection	3053948
100822649	100822672	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	-0.679590746682024	[2,2]	[1,0]	-8	hSpCas9	positive selection	3053949
100819600	100819623	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGTATCCTCCTTAGCCACGGGG	EPHB4	ENSG00000196411	-0.12976239646499357	[3,3]	[3,1]	-2	hSpCas9	positive selection	3053950
100823781	100823804		+	24336571	A375	resistance to PLX after 7 days	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.15466538144176678	[10,9]	[9,8]	-5	hSpCas9	positive selection	3112266
100824198	100824221		+	24336571	A375	resistance to PLX after 7 days	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	0.011262487044587766	[22,20]	[20,22]	0	hSpCas9	positive selection	3112268
100823694	100823717		-	24336571	A375	resistance to PLX after 7 days	CTTCTACTATGAGAGCGATGCGG	EPHB4	ENSG00000196411	-0.06303917639095236	[4,4]	[4,4]	-2	hSpCas9	positive selection	3112269
100823781	100823804		+	24336571	A375	resistance to PLX after 14 days	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.13650064032149828	[9,13]	[3,4]	-1	hSpCas9	positive selection	3170059
100824198	100824221		+	24336571	A375	resistance to PLX after 14 days	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	-0.17699343433684778	[24,19]	[9,7]	-2	hSpCas9	positive selection	3170061
100823694	100823717		-	24336571	A375	resistance to PLX after 14 days	CTTCTACTATGAGAGCGATGCGG	EPHB4	ENSG00000196411	0.05048561634124771	[3,5]	[1,1]	0	hSpCas9	positive selection	3170062
100823781	100823804		+	24336571	A375	viability after 7 days	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.3126107133630214	[8]	[10,9]	5	hSpCas9	negative selection	3227852
100824198	100824221		+	24336571	A375	viability after 7 days	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	0.35700965972292303	[17]	[22,20]	5	hSpCas9	negative selection	3227854
100823694	100823717		-	24336571	A375	viability after 7 days	CTTCTACTATGAGAGCGATGCGG	EPHB4	ENSG00000196411	-0.6041297077285083	[7]	[4,4]	-7	hSpCas9	negative selection	3227855
100823781	100823804		+	24336571	A375	viability after 14 days	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.47750662090824214	[8]	[9,13]	6	hSpCas9	negative selection	3285645
100824198	100824221		+	24336571	A375	viability after 14 days	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	0.389774560291199	[17]	[24,19]	5	hSpCas9	negative selection	3285647
100823694	100823717		-	24336571	A375	viability after 14 days	CTTCTACTATGAGAGCGATGCGG	EPHB4	ENSG00000196411	-0.6369972182761771	[7]	[3,5]	-6	hSpCas9	negative selection	3285648
100823853	100823876	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	1.0364500225567672	[87,60]	[0,0]	5	hSpCas9	positive selection	3348160
100823781	100823804	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.7576366208841941	[88,91]	[0,0]	3	hSpCas9	positive selection	3348161
100817233	100817256	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	4.800468536472364	[3,6]	[0,0]	9	hSpCas9	positive selection	3348162
100817249	100817272	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	0.11777485904704146	[140,140]	[0,0]	0	hSpCas9	positive selection	3367370
100824214	100824237	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.3384629741712407	[120,120]	[0,0]	1	hSpCas9	positive selection	3367371
100824250	100824273	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	-0.05555674383852015	[158,158]	[0,0]	0	hSpCas9	positive selection	3367372
100822632	100822655	7	+	26780180	HT29	viability (Avana library 4 designs)	CTTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.212122625936103	[]	[]	0	hSpCas9	negative selection	3422912
100823770	100823793	7	+	26780180	HT29	viability (Avana library 4 designs)	GAGCATGGTGAAGCGCAGCGTGG	EPHB4	ENSG00000196411	0.787935077509089	[]	[]	3	hSpCas9	negative selection	3422913
100822649	100822672	7	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.351898761153726	[]	[]	1	hSpCas9	negative selection	3422914
100819600	100819623	7	-	26780180	HT29	viability (Avana library 4 designs)	GGGTATCCTCCTTAGCCACGGGG	EPHB4	ENSG00000196411	0.950456294151359	[]	[]	3	hSpCas9	negative selection	3422915
100822632	100822655	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	4.8626681890003	[]	[]	8	hSpCas9	negative selection	3503806
100822649	100822672	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	5.85956579713566	[]	[]	9	hSpCas9	negative selection	3503807
100819600	100819623	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTATCCTCCTTAGCCACGGGG	EPHB4	ENSG00000196411	6.10960258028159	[]	[]	9	hSpCas9	negative selection	3503808
100823770	100823793	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCATGGTGAAGCGCAGCGTGG	EPHB4	ENSG00000196411	3.72689065113222	[]	[]	6	hSpCas9	negative selection	3503809
100819620	100819643	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGGTCACTGCATTGAACGGGG	EPHB4	ENSG00000196411	0.128552392820942	[]	[]	0	hSpCas9	negative selection	3503810
100823915	100823938	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAGTGGGAGGAACTGAGCGG	EPHB4	ENSG00000196411	1.22749214801291	[]	[]	1	hSpCas9	negative selection	3503811
100822632	100822655	7	+	26780180	A375	viability (Avana lentiGuide)	CTTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	2.99772948721587	[]	[]	3	hSpCas9	negative selection	3612465
100822649	100822672	7	-	26780180	A375	viability (Avana lentiGuide)	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	-3.88793383376221	[]	[]	-6	hSpCas9	negative selection	3612466
100819600	100819623	7	-	26780180	A375	viability (Avana lentiGuide)	GGGTATCCTCCTTAGCCACGGGG	EPHB4	ENSG00000196411	-1.73448577700095	[]	[]	-3	hSpCas9	negative selection	3612467
100823770	100823793	7	+	26780180	A375	viability (Avana lentiGuide)	GAGCATGGTGAAGCGCAGCGTGG	EPHB4	ENSG00000196411	-1.56476714652755	[]	[]	-3	hSpCas9	negative selection	3612468
100819620	100819643	7	-	26780180	A375	viability (Avana lentiGuide)	TGAGGTCACTGCATTGAACGGGG	EPHB4	ENSG00000196411	1.67837963277078	[]	[]	2	hSpCas9	negative selection	3612469
100823915	100823938	7	-	26780180	A375	viability (Avana lentiGuide)	GCACAGTGGGAGGAACTGAGCGG	EPHB4	ENSG00000196411	4.87323994867091	[]	[]	4	hSpCas9	negative selection	3612470
100822632	100822655	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.06037722809912484	[4]	[4,5]	1	hSpCas9	positive selection	3721124
100822649	100822672	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.049750667172754115	[3]	[4,3]	1	hSpCas9	positive selection	3721125
100819600	100819623	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTATCCTCCTTAGCCACGGGG	EPHB4	ENSG00000196411	0.2696922516242396	[5]	[6,5]	7	hSpCas9	positive selection	3721126
100823770	100823793	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCATGGTGAAGCGCAGCGTGG	EPHB4	ENSG00000196411	0.2965783489912718	[4]	[5,4]	8	hSpCas9	positive selection	3721127
100819620	100819643	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGGTCACTGCATTGAACGGGG	EPHB4	ENSG00000196411	0.04479983452821522	[5]	[5,4]	1	hSpCas9	positive selection	3721128
100823915	100823938	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAGTGGGAGGAACTGAGCGG	EPHB4	ENSG00000196411	0.04250379040065255	[5]	[5,5]	1	hSpCas9	positive selection	3721129
100822632	100822655	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.02393846884312366	[5]	[3,4]	0	hSpCas9	positive selection	3829731
100822649	100822672	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	-0.2684211341582836	[4]	[2,3]	-4	hSpCas9	positive selection	3829732
100819600	100819623	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTATCCTCCTTAGCCACGGGG	EPHB4	ENSG00000196411	-0.054136549209274826	[6]	[6,3]	-1	hSpCas9	positive selection	3829733
100823770	100823793	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCATGGTGAAGCGCAGCGTGG	EPHB4	ENSG00000196411	0.10406517848640548	[4]	[4,4]	2	hSpCas9	positive selection	3829734
100819620	100819643	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGGTCACTGCATTGAACGGGG	EPHB4	ENSG00000196411	-0.005002467710368802	[6]	[4,5]	0	hSpCas9	positive selection	3829735
100823915	100823938	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAGTGGGAGGAACTGAGCGG	EPHB4	ENSG00000196411	-0.3164296727559919	[5]	[5,2]	-4	hSpCas9	positive selection	3829736
100823781	100823804	7	+	26780180	A375	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	1.37251399693324	[]	[]	7	hSpCas9	negative selection	3937080
100817249	100817272	7	+	26780180	A375	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	1.60479966726855	[]	[]	8	hSpCas9	negative selection	3937081
100824214	100824237	7	-	26780180	A375	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	1.1966464697864	[]	[]	6	hSpCas9	negative selection	3937082
100824250	100824273	7	-	26780180	A375	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.0921859454009338	[]	[]	0	hSpCas9	negative selection	3937083
100817233	100817256	7	-	26780180	A375	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.4070548571405	[]	[]	1	hSpCas9	negative selection	3937084
100823853	100823876	7	-	26780180	A375	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	1.41719172836402	[]	[]	7	hSpCas9	negative selection	3937085
100823781	100823804	7	+	26780180	HT29	viability (GeCKOv2 library)	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.800798075981663	[]	[]	3	hSpCas9	negative selection	4045046
100817249	100817272	7	+	26780180	HT29	viability (GeCKOv2 library)	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	1.40593676586786	[]	[]	7	hSpCas9	negative selection	4045047
100824214	100824237	7	-	26780180	HT29	viability (GeCKOv2 library)	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	1.10445443715645	[]	[]	5	hSpCas9	negative selection	4045048
100824250	100824273	7	-	26780180	HT29	viability (GeCKOv2 library)	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.385071187520163	[]	[]	1	hSpCas9	negative selection	4045049
100817233	100817256	7	-	26780180	HT29	viability (GeCKOv2 library)	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.289999668621261	[]	[]	0	hSpCas9	negative selection	4045050
100823853	100823876	7	-	26780180	HT29	viability (GeCKOv2 library)	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.885432182441679	[]	[]	4	hSpCas9	negative selection	4045051
100823781	100823804	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.005802338169542662	[3]	[1,2]	0	hSpCas9	positive selection	4134985
100824198	100824221	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	0.03914937966837917	[4]	[2,3]	1	hSpCas9	positive selection	4134987
100823694	100823717	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCTACTATGAGAGCGATGCGG	EPHB4	ENSG00000196411	-0.37587469652007977	[1]	[0,0]	-7	hSpCas9	positive selection	4134988
100823781	100823804	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.12829487875470674	[2]	[0,0,1,0]	-2	hSpCas9	positive selection	4199007
100824198	100824221	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACCTGCCCGTCCACCTGAGG	EPHB4	ENSG00000196411	-0.05985820324588799	[4]	[4,0,0,0]	-1	hSpCas9	positive selection	4199009
100823694	100823717	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCTACTATGAGAGCGATGCGG	EPHB4	ENSG00000196411	0.6984815114977705	[3]	[0,0,2,3]	4	hSpCas9	positive selection	4199010
100823853	100823876	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.3161372631204289	[1]	[0,0]	-6	hSpCas9	positive selection	4269009
100823781	100823804	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.005610522186373684	[2]	[2,1]	0	hSpCas9	positive selection	4269010
100817233	100817256	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	-0.04299400436188239	[0]	[0,0]	-1	hSpCas9	positive selection	4269011
100817249	100817272	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.42016189289852585	[2]	[2,0]	-7	hSpCas9	positive selection	4333274
100824214	100824237	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.2012587278471515	[2]	[2,2]	4	hSpCas9	positive selection	4333275
100824250	100824273	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.08328896127818303	[2]	[3,1]	1	hSpCas9	positive selection	4333276
100820178	100820200	7	+	27760321	OCIAML3	viability	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	-0.13752077722191602	[841,682]	[484,609]	-1	hSpCas9	negative selection	4398032
100822325	100822347	7	-	27760321	OCIAML3	viability	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	-0.23478483215536894	[751,518]	[340,516]	-3	hSpCas9	negative selection	4398033
100822449	100822471	7	+	27760321	OCIAML3	viability	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	-0.4666350160828982	[617,548]	[205,490]	-5	hSpCas9	negative selection	4398034
100822633	100822655	7	+	27760321	OCIAML3	viability	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	-0.06079532792991715	[812,682]	[424,732]	0	hSpCas9	negative selection	4398035
100823786	100823808	7	+	27760321	OCIAML3	viability	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	0.15405145919160318	[612,544]	[417,613]	1	hSpCas9	negative selection	4398036
100820178	100820200	7	+	27760321	OCIAML2	viability	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.03598783833147845	[841,682]	[575,698]	0	hSpCas9	negative selection	4481495
100822325	100822347	7	-	27760321	OCIAML2	viability	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.7009958278766086	[751,518]	[736,942]	8	hSpCas9	negative selection	4481496
100822449	100822471	7	+	27760321	OCIAML2	viability	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	-0.16505439629815521	[617,548]	[349,512]	-2	hSpCas9	negative selection	4481497
100822633	100822655	7	+	27760321	OCIAML2	viability	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	-0.004862422927179644	[812,682]	[491,743]	0	hSpCas9	negative selection	4481498
100823786	100823808	7	+	27760321	OCIAML2	viability	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	-0.26735260891896084	[612,544]	[306,495]	-3	hSpCas9	negative selection	4481499
100820178	100820200	7	+	27760321	MV411	viability	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.7323404346994064	[841,682]	[747,956]	5	hSpCas9	negative selection	4564958
100822325	100822347	7	-	27760321	MV411	viability	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.9646469050227788	[751,518]	[811,803]	7	hSpCas9	negative selection	4564959
100822449	100822471	7	+	27760321	MV411	viability	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	0.3449410017135729	[617,548]	[351,692]	2	hSpCas9	negative selection	4564960
100822633	100822655	7	+	27760321	MV411	viability	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.973191782297007	[812,682]	[370,1857]	7	hSpCas9	negative selection	4564961
100823786	100823808	7	+	27760321	MV411	viability	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	0.48405701038041243	[612,544]	[517,556]	3	hSpCas9	negative selection	4564962
100820178	100820200	7	+	27760321	HL60	viability	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.06641691324080046	[841,682]	[574,726]	0	hSpCas9	negative selection	4648421
100822325	100822347	7	-	27760321	HL60	viability	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.06103554816575485	[751,518]	[557,510]	0	hSpCas9	negative selection	4648422
100822449	100822471	7	+	27760321	HL60	viability	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	-0.5864800970055415	[617,548]	[264,371]	-6	hSpCas9	negative selection	4648423
100822633	100822655	7	+	27760321	HL60	viability	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.09865970373613175	[812,682]	[626,677]	1	hSpCas9	negative selection	4648424
100823786	100823808	7	+	27760321	HL60	viability	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	-0.6484103007120661	[612,544]	[260,343]	-6	hSpCas9	negative selection	4648425
100820178	100820200	7	+	27760321	HT1080	viability	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.8833663965087265	[682,532]	[589,289]	5	hSpCas9	negative selection	4731884
100822325	100822347	7	-	27760321	HT1080	viability	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.9983450574972275	[518,404]	[444,282]	5	hSpCas9	negative selection	4731885
100822449	100822471	7	+	27760321	HT1080	viability	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	0.789054655160363	[548,428]	[349,321]	4	hSpCas9	negative selection	4731886
100822633	100822655	7	+	27760321	HT1080	viability	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.6437895117770739	[682,532]	[376,379]	3	hSpCas9	negative selection	4731887
100823786	100823808	7	+	27760321	HT1080	viability	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	0.11425087181929938	[544,424]	[295,113]	0	hSpCas9	negative selection	4731888
100820178	100820200	7	+	27760321	HT29	viability after 7 days	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.22409852732801894	[682,532]	[1320,750,729]	3	hSpCas9	negative selection	4815347
100822325	100822347	7	-	27760321	HT29	viability after 7 days	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.6628644442374905	[518,404]	[775,1255,769]	8	hSpCas9	negative selection	4815348
100822449	100822471	7	+	27760321	HT29	viability after 7 days	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	-0.3532579725478016	[548,428]	[621,430,442]	-5	hSpCas9	negative selection	4815349
100822633	100822655	7	+	27760321	HT29	viability after 7 days	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.2619381196799616	[682,532]	[1094,891,848]	4	hSpCas9	negative selection	4815350
100823786	100823808	7	+	27760321	HT29	viability after 7 days	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	-0.2729432807988955	[544,424]	[364,552,604]	-4	hSpCas9	negative selection	4815351
100820178	100820200	7	+	27760321	HT29	viability after 25 days	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	-0.13240811646765338	[682,532]	[537,620,760]	-1	hSpCas9	negative selection	4898810
100822325	100822347	7	-	27760321	HT29	viability after 25 days	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.5090360018228266	[518,404]	[747,582,941]	5	hSpCas9	negative selection	4898811
100822449	100822471	7	+	27760321	HT29	viability after 25 days	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	0.2813822445543636	[548,428]	[609,760,668]	3	hSpCas9	negative selection	4898812
100822633	100822655	7	+	27760321	HT29	viability after 25 days	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.378539780228598	[682,532]	[718,762,1276]	4	hSpCas9	negative selection	4898813
100823786	100823808	7	+	27760321	HT29	viability after 25 days	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	0.2091524644374395	[544,424]	[519,584,844]	2	hSpCas9	negative selection	4898814
100820178	100820200	7	+	27760321	HT29	viability after 22 days	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	-0.024348883981389347	[682,532]	[830,601,635]	0	hSpCas9	negative selection	4982273
100822325	100822347	7	-	27760321	HT29	viability after 22 days	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.7017329000742145	[518,404]	[719,1021,867]	7	hSpCas9	negative selection	4982274
100822449	100822471	7	+	27760321	HT29	viability after 22 days	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	0.09000772157827847	[548,428]	[449,685,673]	0	hSpCas9	negative selection	4982275
100822633	100822655	7	+	27760321	HT29	viability after 22 days	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.3374295710104317	[682,532]	[960,733,967]	3	hSpCas9	negative selection	4982276
100823786	100823808	7	+	27760321	HT29	viability after 22 days	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	0.17365992060356183	[544,424]	[461,879,558]	1	hSpCas9	negative selection	4982277
100820178	100820200	7	+	27760321	HT29	viability after 19 days	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	-0.23875728901087956	[682,532]	[487,682,585]	-2	hSpCas9	negative selection	5065736
100822325	100822347	7	-	27760321	HT29	viability after 19 days	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.8435946304986843	[518,404]	[856,912,1059]	8	hSpCas9	negative selection	5065737
100822449	100822471	7	+	27760321	HT29	viability after 19 days	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	-0.05145974428769745	[548,428]	[458,710,443]	0	hSpCas9	negative selection	5065738
100822633	100822655	7	+	27760321	HT29	viability after 19 days	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.3705996302364104	[682,532]	[595,721,1329]	3	hSpCas9	negative selection	5065739
100823786	100823808	7	+	27760321	HT29	viability after 19 days	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	-0.23673127809518543	[544,424]	[529,335,548]	-2	hSpCas9	negative selection	5065740
100820178	100820200	7	+	27760321	HT29	viability after 16 days	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.19277621106771203	[682,532]	[943,816,585]	2	hSpCas9	negative selection	5149199
100822325	100822347	7	-	27760321	HT29	viability after 16 days	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.6395382493894921	[518,404]	[836,671,912]	7	hSpCas9	negative selection	5149200
100822449	100822471	7	+	27760321	HT29	viability after 16 days	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	0.031231930466979863	[548,428]	[448,552,664]	0	hSpCas9	negative selection	5149201
100822633	100822655	7	+	27760321	HT29	viability after 16 days	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	-0.0023391735483404563	[682,532]	[658,654,721]	0	hSpCas9	negative selection	5149202
100823786	100823808	7	+	27760321	HT29	viability after 16 days	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	0.032352105295687494	[544,424]	[583,261,828]	0	hSpCas9	negative selection	5149203
100820178	100820200	7	+	27760321	HT29	viability after 13 days	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.12601943301993712	[682,532]	[863,882,573]	1	hSpCas9	negative selection	5232662
100822325	100822347	7	-	27760321	HT29	viability after 13 days	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.4230517740578716	[518,404]	[793,787,581]	5	hSpCas9	negative selection	5232663
100822449	100822471	7	+	27760321	HT29	viability after 13 days	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	0.19448110467387486	[548,428]	[641,868,448]	2	hSpCas9	negative selection	5232664
100822633	100822655	7	+	27760321	HT29	viability after 13 days	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.15530845616580347	[682,532]	[823,775,757]	2	hSpCas9	negative selection	5232665
100823786	100823808	7	+	27760321	HT29	viability after 13 days	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	-0.19322217833479644	[544,424]	[446,531,496]	-2	hSpCas9	negative selection	5232666
100820178	100820200	7	+	27760321	HT29	viability after 10 days	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	-0.08477384264871601	[682,532]	[965,838,353]	-1	hSpCas9	negative selection	5316125
100822325	100822347	7	-	27760321	HT29	viability after 10 days	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.25835673956462296	[518,404]	[808,701,561]	3	hSpCas9	negative selection	5316126
100822449	100822471	7	+	27760321	HT29	viability after 10 days	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	-0.0020084541630591146	[548,428]	[533,540,748]	0	hSpCas9	negative selection	5316127
100822633	100822655	7	+	27760321	HT29	viability after 10 days	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.44098125465464555	[682,532]	[718,1161,1209]	6	hSpCas9	negative selection	5316128
100823786	100823808	7	+	27760321	HT29	viability after 10 days	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	-0.03905566946011618	[544,424]	[740,662,370]	0	hSpCas9	negative selection	5316129
100820178	100820200	7	+	27760321	MOLM13	viability	GAAGTACCCGACGCGGCACTGG	EPHB4	ENSG00000196411	0.7532697500121518	[841,682]	[447,953]	5	hSpCas9	negative selection	5399588
100822325	100822347	7	-	27760321	MOLM13	viability	TGGGCCGAACAGCCGGTCACGG	EPHB4	ENSG00000196411	0.4412359265437108	[751,518]	[499,464]	3	hSpCas9	negative selection	5399589
100822449	100822471	7	+	27760321	MOLM13	viability	AGTCTCCGGGAATCGAGTCAGG	EPHB4	ENSG00000196411	-0.16780940639070996	[617,548]	[297,287]	-1	hSpCas9	negative selection	5399590
100822633	100822655	7	+	27760321	MOLM13	viability	TTCCGGGTGAGATGCTCCGCGG	EPHB4	ENSG00000196411	0.0640978532632257	[812,682]	[331,530]	0	hSpCas9	negative selection	5399591
100823786	100823808	7	+	27760321	MOLM13	viability	AGCGTGGCGTACACGTGGACGG	EPHB4	ENSG00000196411	0.49140031881265306	[612,544]	[632,309]	3	hSpCas9	negative selection	5399592
100823853	100823876	7	-	27260156	BXPC3	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.3676920835292157	[196]	[147,149,170,171]	-7	hSpCas9	negative selection	5541469
100823781	100823804	7	+	27260156	BXPC3	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.3735039745513094	[447]	[304,356,397,394]	-7	hSpCas9	negative selection	5541470
100817233	100817256	7	-	27260156	BXPC3	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.3339865287676189	[48]	[15,49,120,79]	7	hSpCas9	negative selection	5541471
100817249	100817272	7	+	27260156	BXPC3	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.18596608468636258	[407]	[328,412,343,418]	-4	hSpCas9	negative selection	5605734
100824214	100824237	7	-	27260156	BXPC3	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.27843765730174064	[346]	[337,478,387,576]	6	hSpCas9	negative selection	5605735
100824250	100824273	7	-	27260156	BXPC3	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.31916162060883035	[396]	[516,447,477,643]	7	hSpCas9	negative selection	5605736
100823853	100823876	7	-	27260156	A673	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.11471582156812854	[196]	[229,174,172,302]	-3	hSpCas9	negative selection	5662720
100823781	100823804	7	+	27260156	A673	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.22122876887190662	[447]	[544,361,369,587]	-5	hSpCas9	negative selection	5662721
100817233	100817256	7	-	27260156	A673	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	-0.12702276900374132	[48]	[97,54,25,40]	-3	hSpCas9	negative selection	5662722
100817249	100817272	7	+	27260156	A673	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.3650791881140726	[407]	[349,409,382,372]	-7	hSpCas9	negative selection	5726985
100824214	100824237	7	-	27260156	A673	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.21834844298333445	[346]	[533,556,349,502]	5	hSpCas9	negative selection	5726986
100824250	100824273	7	-	27260156	A673	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.36780608408020443	[396]	[716,600,597,551]	8	hSpCas9	negative selection	5726987
100823853	100823876	7	-	27260156	A375	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.5001028777091527	[196]	[125,207,194,130]	-6	hSpCas9	negative selection	5783971
100823781	100823804	7	+	27260156	A375	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.35656899454522917	[447]	[435,439,272,479]	-5	hSpCas9	negative selection	5783972
100817233	100817256	7	-	27260156	A375	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.38238763607102433	[48]	[97,51,59,83]	5	hSpCas9	negative selection	5783973
100817249	100817272	7	+	27260156	A375	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.08313079021222888	[407]	[355,594,460,409]	-1	hSpCas9	negative selection	5848236
100824214	100824237	7	-	27260156	A375	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.2387999604793482	[346]	[302,401,383,296]	-3	hSpCas9	negative selection	5848237
100824250	100824273	7	-	27260156	A375	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.6107061793924291	[396]	[656,916,740,560]	8	hSpCas9	negative selection	5848238
100823853	100823876	7	-	27260156	COLO741	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.14846304641573727	[196]	[438,234,182]	3	hSpCas9	negative selection	5905222
100823781	100823804	7	+	27260156	COLO741	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.35785096920276327	[447]	[585,421,349]	-6	hSpCas9	negative selection	5905223
100817233	100817256	7	-	27260156	COLO741	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.42494192016253507	[48]	[55,16,169]	8	hSpCas9	negative selection	5905224
100817249	100817272	7	+	27260156	COLO741	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.17404055492834644	[407]	[384,506,484]	-4	hSpCas9	negative selection	5969487
100824214	100824237	7	-	27260156	COLO741	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.08011455459911726	[346]	[543,448,284]	-2	hSpCas9	negative selection	5969488
100824250	100824273	7	-	27260156	COLO741	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.5809338921014836	[396]	[673,868,726]	9	hSpCas9	negative selection	5969489
100823853	100823876	7	-	27260156	CAL120	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.22532995161832936	[196]	[450,125,306]	3	hSpCas9	negative selection	6026473
100823781	100823804	7	+	27260156	CAL120	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.43995994748971234	[447]	[621,965,661]	6	hSpCas9	negative selection	6026474
100817233	100817256	7	-	27260156	CAL120	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	1.8180194488729082	[48]	[470,85,127]	9	hSpCas9	negative selection	6026475
100817249	100817272	7	+	27260156	CAL120	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.5737076337497942	[407]	[304,438,274]	-7	hSpCas9	negative selection	6090738
100824214	100824237	7	-	27260156	CAL120	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.3578967385131766	[346]	[768,629,297]	5	hSpCas9	negative selection	6090739
100824250	100824273	7	-	27260156	CAL120	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.3512688376608494	[396]	[399,727,725]	5	hSpCas9	negative selection	6090740
100823853	100823876	7	-	27260156	CADOES1	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.26099745029017374	[196]	[70,191,141,208]	-4	hSpCas9	negative selection	6147724
100823781	100823804	7	+	27260156	CADOES1	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.520139177318464	[447]	[313,280,278,287]	-7	hSpCas9	negative selection	6147725
100817233	100817256	7	-	27260156	CADOES1	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.5931105496032236	[48]	[125,54,45,46]	8	hSpCas9	negative selection	6147726
100817249	100817272	7	+	27260156	CADOES1	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.29588645303803696	[407]	[369,379,289,191]	-5	hSpCas9	negative selection	6211989
100824214	100824237	7	-	27260156	CADOES1	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.11618220410950686	[346]	[274,486,253,384]	2	hSpCas9	negative selection	6211990
100824250	100824273	7	-	27260156	CADOES1	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.24477899393943603	[396]	[487,374,417,469]	4	hSpCas9	negative selection	6211991
100823853	100823876	7	-	27260156	EWS502	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.21218050221484064	[196]	[150,148,188,239]	-4	hSpCas9	negative selection	6268975
100823781	100823804	7	+	27260156	EWS502	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.01116845505965379	[447]	[414,447,724,291]	0	hSpCas9	negative selection	6268976
100817233	100817256	7	-	27260156	EWS502	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	-0.32950059904583995	[48]	[14,73,33,43]	-5	hSpCas9	negative selection	6268977
100817249	100817272	7	+	27260156	EWS502	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.4290876229967213	[407]	[318,273,330,363]	-6	hSpCas9	negative selection	6333240
100824214	100824237	7	-	27260156	EWS502	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.13295588438229933	[346]	[354,473,350,434]	2	hSpCas9	negative selection	6333241
100824250	100824273	7	-	27260156	EWS502	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.7447732240416793	[396]	[549,657,870,763]	9	hSpCas9	negative selection	6333242
100823853	100823876	7	-	27260156	EW8	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.251991075194953	[196]	[90,66,166,199]	-5	hSpCas9	negative selection	6390226
100823781	100823804	7	+	27260156	EW8	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.10366093431331126	[447]	[318,345,292,397]	-2	hSpCas9	negative selection	6390227
100817233	100817256	7	-	27260156	EW8	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.04658816927850218	[48]	[53,31,42,35]	0	hSpCas9	negative selection	6390228
100817249	100817272	7	+	27260156	EW8	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.2758370517993065	[407]	[383,229,229,266]	-5	hSpCas9	negative selection	6454491
100824214	100824237	7	-	27260156	EW8	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.27961525070407134	[346]	[520,348,219,314]	5	hSpCas9	negative selection	6454492
100824250	100824273	7	-	27260156	EW8	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.41007820762099845	[396]	[388,338,353,633]	7	hSpCas9	negative selection	6454493
100823853	100823876	7	-	27260156	CORL105	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.28571291594385795	[196]	[342,184,347,262]	5	hSpCas9	negative selection	6511477
100823781	100823804	7	+	27260156	CORL105	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.23397188520910778	[447]	[417,528,362,457]	-4	hSpCas9	negative selection	6511478
100817233	100817256	7	-	27260156	CORL105	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.48740382738726806	[48]	[72,70,145,41]	8	hSpCas9	negative selection	6511479
100817249	100817272	7	+	27260156	CORL105	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.04730754861011702	[407]	[480,412,641,342]	-1	hSpCas9	negative selection	6575742
100824214	100824237	7	-	27260156	CORL105	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.15386565550699288	[346]	[390,339,428,311]	-3	hSpCas9	negative selection	6575743
100824250	100824273	7	-	27260156	CORL105	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.40600193923370526	[396]	[671,603,625,564]	7	hSpCas9	negative selection	6575744
100823853	100823876	7	-	27260156	HS294T	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.5841196280941536	[196]	[103,118,75,166]	7	hSpCas9	negative selection	6632728
100823781	100823804	7	+	27260156	HS294T	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.2199841283554645	[447]	[118,146,354,193]	3	hSpCas9	negative selection	6632729
100817233	100817256	7	-	27260156	HS294T	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.8649775795781149	[48]	[26,40,22,49]	9	hSpCas9	negative selection	6632730
100817249	100817272	7	+	27260156	HS294T	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	0.16924451193150933	[407]	[154,140,155,276]	2	hSpCas9	negative selection	6696993
100824214	100824237	7	-	27260156	HS294T	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.42334984755583976	[346]	[84,113,90,112]	-6	hSpCas9	negative selection	6696994
100824250	100824273	7	-	27260156	HS294T	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.3008034546296395	[396]	[193,175,189,196]	4	hSpCas9	negative selection	6696995
100823853	100823876	7	-	27260156	HCC44	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.31538137109999154	[196]	[133,154,294,150]	-5	hSpCas9	negative selection	6753979
100823781	100823804	7	+	27260156	HCC44	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.17999555930791605	[447]	[596,468,410,316]	-3	hSpCas9	negative selection	6753980
100817233	100817256	7	-	27260156	HCC44	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.20829774287761138	[48]	[41,37,185,13]	3	hSpCas9	negative selection	6753981
100817249	100817272	7	+	27260156	HCC44	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.26487186986181754	[407]	[394,251,682,277]	-4	hSpCas9	negative selection	6818244
100824214	100824237	7	-	27260156	HCC44	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.02402490724096329	[346]	[384,343,548,348]	0	hSpCas9	negative selection	6818245
100824250	100824273	7	-	27260156	HCC44	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.22997406983482838	[396]	[505,524,737,372]	3	hSpCas9	negative selection	6818246
100823853	100823876	7	-	27260156	G402	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.2777017192295794	[196]	[289,256,317,296]	3	hSpCas9	negative selection	6875230
100823781	100823804	7	+	27260156	G402	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.40816338558811316	[447]	[607,319,431,313]	-5	hSpCas9	negative selection	6875231
100817233	100817256	7	-	27260156	G402	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	-0.1458210109544127	[48]	[137,24,0,61]	-2	hSpCas9	negative selection	6875232
100817249	100817272	7	+	27260156	G402	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	0.10116742095355513	[407]	[517,450,648,509]	1	hSpCas9	negative selection	6939495
100824214	100824237	7	-	27260156	G402	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.21023927942550089	[346]	[374,829,400,360]	2	hSpCas9	negative selection	6939496
100824250	100824273	7	-	27260156	G402	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.6255718380319241	[396]	[710,620,915,726]	7	hSpCas9	negative selection	6939497
100823853	100823876	7	-	27260156	L33	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.28208320040590096	[196]	[260,116,135,194]	6	hSpCas9	negative selection	6996481
100823781	100823804	7	+	27260156	L33	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.04894370503331755	[447]	[413,162,374,325]	-1	hSpCas9	negative selection	6996482
100817233	100817256	7	-	27260156	L33	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.530901320521115	[48]	[79,47,33,31]	9	hSpCas9	negative selection	6996483
100817249	100817272	7	+	27260156	L33	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.23898250691658082	[407]	[372,133,186,383]	-5	hSpCas9	negative selection	7060746
100824214	100824237	7	-	27260156	L33	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.30336371688957114	[346]	[263,106,199,281]	-6	hSpCas9	negative selection	7060747
100824250	100824273	7	-	27260156	L33	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.12112199621153273	[396]	[431,178,256,448]	2	hSpCas9	negative selection	7060748
100823853	100823876	7	-	27260156	K562	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.6885002145398045	[196]	[220,154,53,24]	-7	hSpCas9	negative selection	7117732
100823781	100823804	7	+	27260156	K562	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.49759610204580657	[447]	[398,208,137,373]	-5	hSpCas9	negative selection	7117733
100817233	100817256	7	-	27260156	K562	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	-0.017834183395184056	[48]	[54,9,82,24]	0	hSpCas9	negative selection	7117734
100817249	100817272	7	+	27260156	K562	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.3425850106307481	[407]	[324,134,359,312]	-4	hSpCas9	negative selection	7181997
100824214	100824237	7	-	27260156	K562	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.07279174581159958	[346]	[391,253,227,300]	-1	hSpCas9	negative selection	7181998
100824250	100824273	7	-	27260156	K562	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.06652843135458786	[396]	[427,340,277,423]	0	hSpCas9	negative selection	7181999
100823853	100823876	7	-	27260156	HT29	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.03394782976194066	[196]	[136,368,227,246]	0	hSpCas9	negative selection	7238983
100823781	100823804	7	+	27260156	HT29	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.3650992698134565	[447]	[313,374,556,428]	-6	hSpCas9	negative selection	7238984
100817233	100817256	7	-	27260156	HT29	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.257418206259036	[48]	[98,78,72,39]	5	hSpCas9	negative selection	7238985
100817249	100817272	7	+	27260156	HT29	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.309729819268029	[407]	[389,495,344,376]	-6	hSpCas9	negative selection	7303248
100824214	100824237	7	-	27260156	HT29	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.2419776663185684	[346]	[617,387,509,477]	5	hSpCas9	negative selection	7303249
100824250	100824273	7	-	27260156	HT29	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.5026791402402472	[396]	[773,718,598,651]	8	hSpCas9	negative selection	7303250
100823853	100823876	7	-	27260156	MHHES1	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.03281000240502263	[196]	[225,305,193,159]	0	hSpCas9	negative selection	7360234
100823781	100823804	7	+	27260156	MHHES1	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.39513537910288593	[447]	[550,393,333,289]	-6	hSpCas9	negative selection	7360235
100817233	100817256	7	-	27260156	MHHES1	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.900772957848345	[48]	[101,167,63,85]	9	hSpCas9	negative selection	7360236
100817249	100817272	7	+	27260156	MHHES1	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.1220335939066444	[407]	[448,455,406,382]	-2	hSpCas9	negative selection	7424499
100824214	100824237	7	-	27260156	MHHES1	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.006911954419451916	[346]	[486,352,484,260]	0	hSpCas9	negative selection	7424500
100824250	100824273	7	-	27260156	MHHES1	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.15774829206295726	[396]	[431,479,608,461]	3	hSpCas9	negative selection	7424501
100823853	100823876	7	-	27260156	MEWO	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.13479089165757685	[196]	[196,198,209]	3	hSpCas9	negative selection	7481485
100823781	100823804	7	+	27260156	MEWO	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.03961405758187326	[447]	[511,437,357]	0	hSpCas9	negative selection	7481486
100817233	100817256	7	-	27260156	MEWO	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.1595377266881406	[48]	[52,39,60]	3	hSpCas9	negative selection	7481487
100817249	100817272	7	+	27260156	MEWO	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.02749620618746665	[407]	[443,351,340]	0	hSpCas9	negative selection	7545750
100824214	100824237	7	-	27260156	MEWO	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.018422781740826066	[346]	[296,306,352]	0	hSpCas9	negative selection	7545751
100824250	100824273	7	-	27260156	MEWO	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.3150064220877652	[396]	[401,546,424]	6	hSpCas9	negative selection	7545752
100823853	100823876	7	-	27260156	LNCAPCLONEFGC	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.34269504129718986	[196]	[100,153,189,124]	-5	hSpCas9	negative selection	7602736
100823781	100823804	7	+	27260156	LNCAPCLONEFGC	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.2887491773094471	[447]	[311,339,402,283]	-4	hSpCas9	negative selection	7602737
100817233	100817256	7	-	27260156	LNCAPCLONEFGC	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.21591041123581522	[48]	[39,38,49,77]	3	hSpCas9	negative selection	7602738
100817249	100817272	7	+	27260156	LNCAPCLONEFGC	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.09810555420482411	[407]	[310,316,422,343]	-1	hSpCas9	negative selection	7667001
100824214	100824237	7	-	27260156	LNCAPCLONEFGC	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.14555561768225717	[346]	[379,290,396,332]	2	hSpCas9	negative selection	7667002
100824250	100824273	7	-	27260156	LNCAPCLONEFGC	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.28262840721506216	[396]	[438,402,519,401]	4	hSpCas9	negative selection	7667003
100823853	100823876	7	-	27260156	PANC0327	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	1.058481024838486	[196]	[605,513,135,201]	9	hSpCas9	negative selection	7723987
100823781	100823804	7	+	27260156	PANC0327	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.2777831949113148	[447]	[527,523,426,448]	4	hSpCas9	negative selection	7723988
100817233	100817256	7	-	27260156	PANC0327	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	1.213852348255473	[48]	[138,107,73,84]	9	hSpCas9	negative selection	7723989
100817249	100817272	7	+	27260156	PANC0327	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	0.009088369670931656	[407]	[322,350,328,453]	0	hSpCas9	negative selection	7788252
100824214	100824237	7	-	27260156	PANC0327	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.12396384765129848	[346]	[551,289,233,290]	1	hSpCas9	negative selection	7788253
100824250	100824273	7	-	27260156	PANC0327	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.2770542195219413	[396]	[697,352,401,287]	4	hSpCas9	negative selection	7788254
100823853	100823876	7	-	27260156	NCIH2009	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.4723419887362488	[196]	[437,437,278]	6	hSpCas9	negative selection	7845238
100823781	100823804	7	+	27260156	NCIH2009	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.08977141018089334	[447]	[848,535,430]	-1	hSpCas9	negative selection	7845239
100817233	100817256	7	-	27260156	NCIH2009	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.5043075368481973	[48]	[100,37,153]	7	hSpCas9	negative selection	7845240
100817249	100817272	7	+	27260156	NCIH2009	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.25166790420422636	[407]	[522,384,537]	-3	hSpCas9	negative selection	7909503
100824214	100824237	7	-	27260156	NCIH2009	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.33139175156149786	[346]	[291,486,355]	-4	hSpCas9	negative selection	7909504
100824250	100824273	7	-	27260156	NCIH2009	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.3925059678668861	[396]	[840,638,726]	5	hSpCas9	negative selection	7909505
100823853	100823876	7	-	27260156	NCIH1373	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.6229123061803413	[196]	[179,139,485,146]	6	hSpCas9	negative selection	7966489
100823781	100823804	7	+	27260156	NCIH1373	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.7420042891932407	[447]	[422,422,143,55]	-6	hSpCas9	negative selection	7966490
100817233	100817256	7	-	27260156	NCIH1373	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.5010539890480081	[48]	[45,155,54,9]	5	hSpCas9	negative selection	7966491
100817249	100817272	7	+	27260156	NCIH1373	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.4154979521691058	[407]	[745,234,219,62]	-4	hSpCas9	negative selection	8030754
100824214	100824237	7	-	27260156	NCIH1373	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.9352707493927184	[346]	[195,201,137,73]	-7	hSpCas9	negative selection	8030755
100824250	100824273	7	-	27260156	NCIH1373	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	-0.029420883168680745	[396]	[341,468,277,170]	0	hSpCas9	negative selection	8030756
100823853	100823876	7	-	27260156	PATU8902	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.4041261528886907	[196]	[439,361,428,177]	4	hSpCas9	negative selection	8087740
100823781	100823804	7	+	27260156	PATU8902	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.4321175842297608	[447]	[311,397,658,422]	-4	hSpCas9	negative selection	8087741
100817233	100817256	7	-	27260156	PATU8902	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	-0.07754747482697644	[48]	[94,54,40,73]	-1	hSpCas9	negative selection	8087742
100817249	100817272	7	+	27260156	PATU8902	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.08166977291434732	[407]	[611,717,208,709]	-1	hSpCas9	negative selection	8152005
100824214	100824237	7	-	27260156	PATU8902	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.4397065699927423	[346]	[401,467,131,494]	-4	hSpCas9	negative selection	8152006
100824250	100824273	7	-	27260156	PATU8902	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.48374580140825263	[396]	[767,708,788,821]	5	hSpCas9	negative selection	8152007
100823853	100823876	7	-	27260156	PANC1	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.11738916992129256	[196]	[174,147,215,184]	1	hSpCas9	negative selection	8208991
100823781	100823804	7	+	27260156	PANC1	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.10811656538034801	[447]	[370,558,156,371]	-2	hSpCas9	negative selection	8208992
100817233	100817256	7	-	27260156	PANC1	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.8051534738935104	[48]	[61,191,49,21]	9	hSpCas9	negative selection	8208993
100817249	100817272	7	+	27260156	PANC1	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.4291124534473737	[407]	[295,312,301,153]	-6	hSpCas9	negative selection	8273256
100824214	100824237	7	-	27260156	PANC1	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.2907719292284826	[346]	[418,317,357,348]	5	hSpCas9	negative selection	8273257
100824250	100824273	7	-	27260156	PANC1	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.39193935818104414	[396]	[391,630,532,291]	6	hSpCas9	negative selection	8273258
100823853	100823876	7	-	27260156	PANC0813	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.3409425584122576	[196]	[341,269,282,281]	5	hSpCas9	negative selection	8330242
100823781	100823804	7	+	27260156	PANC0813	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.09148927585825097	[447]	[498,603,486,390]	-1	hSpCas9	negative selection	8330243
100817233	100817256	7	-	27260156	PANC0813	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.19760395919462814	[48]	[50,51,64,92]	3	hSpCas9	negative selection	8330244
100817249	100817272	7	+	27260156	PANC0813	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	0.05430036732007257	[407]	[659,435,421,486]	0	hSpCas9	negative selection	8394507
100824214	100824237	7	-	27260156	PANC0813	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.22056133496459968	[346]	[327,323,413,331]	-4	hSpCas9	negative selection	8394508
100824250	100824273	7	-	27260156	PANC0813	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.886743613391637	[396]	[677,710,1263,783]	9	hSpCas9	negative selection	8394509
100823853	100823876	7	-	27260156	RDES	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.021812058184276006	[196]	[174,193,248,292]	0	hSpCas9	negative selection	8451493
100823781	100823804	7	+	27260156	RDES	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.39399631047837713	[447]	[344,345,383,513]	-6	hSpCas9	negative selection	8451494
100817233	100817256	7	-	27260156	RDES	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.2128782346781013	[48]	[20,69,69,115]	3	hSpCas9	negative selection	8451495
100817249	100817272	7	+	27260156	RDES	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.2446257961268711	[407]	[341,289,453,530]	-4	hSpCas9	negative selection	8515758
100824214	100824237	7	-	27260156	RDES	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.15020239686062808	[346]	[307,394,442,683]	2	hSpCas9	negative selection	8515759
100824250	100824273	7	-	27260156	RDES	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.17661017299733756	[396]	[406,438,563,699]	3	hSpCas9	negative selection	8515760
100823853	100823876	7	-	27260156	PC3	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.156742949450408	[196]	[129,157,312,338]	3	hSpCas9	negative selection	8572744
100823781	100823804	7	+	27260156	PC3	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.4470011579360656	[447]	[521,531,897,556]	8	hSpCas9	negative selection	8572745
100817233	100817256	7	-	27260156	PC3	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.47098630850187506	[48]	[27,152,80,18]	8	hSpCas9	negative selection	8572746
100817249	100817272	7	+	27260156	PC3	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.1910182649955676	[407]	[256,353,651,277]	-4	hSpCas9	negative selection	8637009
100824214	100824237	7	-	27260156	PC3	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.2962239924557051	[346]	[341,326,719,414]	6	hSpCas9	negative selection	8637010
100824250	100824273	7	-	27260156	PC3	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.08212304653329408	[396]	[272,445,665,405]	1	hSpCas9	negative selection	8637011
100823853	100823876	7	-	27260156	PATU8988T	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.19418706184956291	[196]	[149,319,124,292]	3	hSpCas9	negative selection	8693995
100823781	100823804	7	+	27260156	PATU8988T	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.0685715963594258	[447]	[243,511,433,646]	1	hSpCas9	negative selection	8693996
100817233	100817256	7	-	27260156	PATU8988T	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.591394709393545	[48]	[143,73,22,42]	8	hSpCas9	negative selection	8693997
100817249	100817272	7	+	27260156	PATU8988T	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.8403107577862788	[407]	[191,234,194,263]	-8	hSpCas9	negative selection	8758260
100824214	100824237	7	-	27260156	PATU8988T	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.16180567342445418	[346]	[524,295,258,417]	2	hSpCas9	negative selection	8758261
100824250	100824273	7	-	27260156	PATU8988T	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.4211842787962288	[396]	[535,400,640,459]	7	hSpCas9	negative selection	8758262
100823853	100823876	7	-	27260156	T47D	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.11493410681096705	[196]	[203,183,217,244]	-3	hSpCas9	negative selection	8815246
100823781	100823804	7	+	27260156	T47D	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.04496489435011705	[447]	[573,414,518,523]	-1	hSpCas9	negative selection	8815247
100817233	100817256	7	-	27260156	T47D	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.4879215219201427	[48]	[61,89,89,76]	8	hSpCas9	negative selection	8815248
100817249	100817272	7	+	27260156	T47D	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.17384500560530328	[407]	[416,358,442,472]	-4	hSpCas9	negative selection	8879511
100824214	100824237	7	-	27260156	T47D	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.2429876107851813	[346]	[439,416,439,626]	5	hSpCas9	negative selection	8879512
100824250	100824273	7	-	27260156	T47D	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.40435212636849793	[396]	[576,516,671,691]	8	hSpCas9	negative selection	8879513
100823853	100823876	7	-	27260156	SU8686	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	0.36134926628467134	[196]	[233,207,287,285]	6	hSpCas9	negative selection	8936497
100823781	100823804	7	+	27260156	SU8686	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.13858940323426594	[447]	[343,344,399,561]	-2	hSpCas9	negative selection	8936498
100817233	100817256	7	-	27260156	SU8686	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.25294004099504397	[48]	[44,17,71,111]	4	hSpCas9	negative selection	8936499
100817249	100817272	7	+	27260156	SU8686	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	0.045652120687135866	[407]	[413,359,476,426]	0	hSpCas9	negative selection	9000762
100824214	100824237	7	-	27260156	SU8686	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.09644417247333786	[346]	[315,339,347,493]	1	hSpCas9	negative selection	9000763
100824250	100824273	7	-	27260156	SU8686	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.46898260545433795	[396]	[491,594,495,598]	7	hSpCas9	negative selection	9000764
100823853	100823876	7	-	27260156	SKES1	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.035583832443007335	[196]	[206,192,223,147]	0	hSpCas9	negative selection	9057748
100823781	100823804	7	+	27260156	SKES1	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.12513736445468127	[447]	[363,578,367,345]	-3	hSpCas9	negative selection	9057749
100817233	100817256	7	-	27260156	SKES1	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.8363256430206025	[48]	[68,87,74,110]	9	hSpCas9	negative selection	9057750
100817249	100817272	7	+	27260156	SKES1	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.13810988543080263	[407]	[425,476,203,388]	-3	hSpCas9	negative selection	9122013
100824214	100824237	7	-	27260156	SKES1	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.16470066490944274	[346]	[558,344,390,283]	3	hSpCas9	negative selection	9122014
100824250	100824273	7	-	27260156	SKES1	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.5153329077460853	[396]	[522,756,524,480]	9	hSpCas9	negative selection	9122015
100823853	100823876	7	-	27260156	TOV112D	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.3332885375758412	[196]	[85,166,184,183]	-6	hSpCas9	negative selection	9178999
100823781	100823804	7	+	27260156	TOV112D	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	0.2685414552806273	[447]	[559,465,273,835]	5	hSpCas9	negative selection	9179000
100817233	100817256	7	-	27260156	TOV112D	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.06145968879751962	[48]	[29,47,29,92]	1	hSpCas9	negative selection	9179001
100817249	100817272	7	+	27260156	TOV112D	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.2341127778950525	[407]	[342,531,241,317]	-4	hSpCas9	negative selection	9243264
100824214	100824237	7	-	27260156	TOV112D	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.4303763153060954	[346]	[274,395,753,414]	7	hSpCas9	negative selection	9243265
100824250	100824273	7	-	27260156	TOV112D	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.17538034642983136	[396]	[420,467,545,364]	3	hSpCas9	negative selection	9243266
100823853	100823876	7	-	27260156	TC71	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.2431204223393093	[196]	[198,174,178,158]	-6	hSpCas9	negative selection	9300250
100823781	100823804	7	+	27260156	TC71	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.014832345871085187	[447]	[385,467,511,539]	0	hSpCas9	negative selection	9300251
100817233	100817256	7	-	27260156	TC71	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.5284061002229663	[48]	[116,60,48,75]	9	hSpCas9	negative selection	9300252
100817249	100817272	7	+	27260156	TC71	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.15243701006022245	[407]	[347,380,381,468]	-4	hSpCas9	negative selection	9364515
100824214	100824237	7	-	27260156	TC71	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	0.23180067410828548	[346]	[394,445,528,370]	6	hSpCas9	negative selection	9364516
100824250	100824273	7	-	27260156	TC71	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.30347095231828214	[396]	[491,555,471,586]	7	hSpCas9	negative selection	9364517
100823853	100823876	7	-	27260156	TC32	viability	GTGTGACGTGCAGCGTGCCCCGG	EPHB4	ENSG00000196411	-0.36234440438692017	[196]	[163,61,226,158]	-6	hSpCas9	negative selection	9421501
100823781	100823804	7	+	27260156	TC32	viability	AGCGCAGCGTGGCGTACACGTGG	EPHB4	ENSG00000196411	-0.3545625792510852	[447]	[333,163,526,372]	-6	hSpCas9	negative selection	9421502
100817233	100817256	7	-	27260156	TC32	viability	GCGCGCTCTGAGGCCGGCTACGG	EPHB4	ENSG00000196411	0.6840261842111586	[48]	[63,85,82,54]	9	hSpCas9	negative selection	9421503
100817249	100817272	7	+	27260156	TC32	viability	AGCGCGCCCGTACCTGCACCAGG	EPHB4	ENSG00000196411	-0.19061523194477983	[407]	[294,276,373,415]	-3	hSpCas9	negative selection	9485766
100824214	100824237	7	-	27260156	TC32	viability	GAAGTGGGTGACATTCCCTCAGG	EPHB4	ENSG00000196411	-0.04989297569438528	[346]	[319,259,319,363]	-1	hSpCas9	negative selection	9485767
100824250	100824273	7	-	27260156	TC32	viability	GACCCTGCTGAACACAAAATTGG	EPHB4	ENSG00000196411	0.45625328222280237	[396]	[361,585,526,532]	7	hSpCas9	negative selection	9485768
100818600	100818623	7	+	27869803	HPAFII	viability after 27 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.3264118762063431	[213]	[98,81,NaN]	-2	hSpCas9	negative selection	9597289
100819556	100819579	7	-	27869803	HPAFII	viability after 27 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-1.6648961000027596	[419]	[55,80,NaN]	-8	hSpCas9	negative selection	9597290
100822353	100822376	7	+	27869803	HPAFII	viability after 27 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.5721987059605286	[116]	[115,70,NaN]	4	hSpCas9	negative selection	9597291
100823682	100823705	7	-	27869803	HPAFII	viability after 27 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.8894079520675537	[187]	[265,113,NaN]	7	hSpCas9	negative selection	9597292
100824202	100824225	7	-	27869803	HPAFII	viability after 27 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.2995492317626613	[67]	[87,87,NaN]	9	hSpCas9	negative selection	9597293
100818600	100818623	7	+	27869803	HPAFII	viability after 15 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.1561210952507118	[213]	[193,294,NaN]	1	hSpCas9	negative selection	9679738
100819556	100819579	7	-	27869803	HPAFII	viability after 15 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-1.263210708474665	[419]	[237,156,NaN]	-8	hSpCas9	negative selection	9679739
100822353	100822376	7	+	27869803	HPAFII	viability after 15 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.6812454470629514	[116]	[192,206,NaN]	7	hSpCas9	negative selection	9679740
100823682	100823705	7	-	27869803	HPAFII	viability after 15 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.00943226694762378	[187]	[285,151,NaN]	0	hSpCas9	negative selection	9679741
100824202	100824225	7	-	27869803	HPAFII	viability after 15 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.286013663962741	[67]	[303,99,NaN]	9	hSpCas9	negative selection	9679742
100818600	100818623	7	+	27869803	ASPC1	viability after 36 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.19139541864075926	[451]	[303,191,81]	2	hSpCas9	negative selection	9762187
100819556	100819579	7	-	27869803	ASPC1	viability after 36 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.0987861484519027	[1058]	[377,486,205]	-1	hSpCas9	negative selection	9762188
100822353	100822376	7	+	27869803	ASPC1	viability after 36 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	-0.19335729644566824	[328]	[108,13,161]	-2	hSpCas9	negative selection	9762189
100823682	100823705	7	-	27869803	ASPC1	viability after 36 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	1.661919321298833	[477]	[603,832,226]	9	hSpCas9	negative selection	9762190
100824202	100824225	7	-	27869803	ASPC1	viability after 36 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	-1.347522810850265	[167]	[11,24,28]	-8	hSpCas9	negative selection	9762191
100818600	100818623	7	+	27869803	PATU8988S	viability after 35 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.1822025005330431	[382]	[114,156,NaN]	-2	hSpCas9	negative selection	9844636
100819556	100819579	7	-	27869803	PATU8988S	viability after 35 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.07317780208632796	[726]	[322,292,NaN]	0	hSpCas9	negative selection	9844637
100822353	100822376	7	+	27869803	PATU8988S	viability after 35 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	-0.48373023877600196	[272]	[134,21,NaN]	-5	hSpCas9	negative selection	9844638
100823682	100823705	7	-	27869803	PATU8988S	viability after 35 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.04376044078509039	[399]	[192,138,NaN]	0	hSpCas9	negative selection	9844639
100824202	100824225	7	-	27869803	PATU8988S	viability after 35 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.316870071137207	[226]	[341,112,NaN]	9	hSpCas9	negative selection	9844640
100818600	100818623	7	+	27869803	PATU8988S	viability after 31 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	0.32961558906286	[382]	[183,201,NaN]	4	hSpCas9	negative selection	9927085
100819556	100819579	7	-	27869803	PATU8988S	viability after 31 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.3595154171417127	[726]	[385,353,NaN]	4	hSpCas9	negative selection	9927086
100822353	100822376	7	+	27869803	PATU8988S	viability after 31 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	-0.37599911252669027	[272]	[93,70,NaN]	-4	hSpCas9	negative selection	9927087
100823682	100823705	7	-	27869803	PATU8988S	viability after 31 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.12182703909117548	[399]	[129,228,NaN]	1	hSpCas9	negative selection	9927088
100824202	100824225	7	-	27869803	PATU8988S	viability after 31 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.0049605722453037	[226]	[244,100,NaN]	9	hSpCas9	negative selection	9927089
100818600	100818623	7	+	27869803	HPAFII	viability after 35 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-1.0591580531643556	[213]	[35,69,NaN]	-5	hSpCas9	negative selection	10009534
100819556	100819579	7	-	27869803	HPAFII	viability after 35 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-1.839593150560031	[419]	[49,69,NaN]	-7	hSpCas9	negative selection	10009535
100822353	100822376	7	+	27869803	HPAFII	viability after 35 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.5223218213428681	[116]	[109,56,NaN]	3	hSpCas9	negative selection	10009536
100823682	100823705	7	-	27869803	HPAFII	viability after 35 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.5143334695629903	[187]	[134,136,NaN]	3	hSpCas9	negative selection	10009537
100824202	100824225	7	-	27869803	HPAFII	viability after 35 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	0.7181817590379869	[67]	[26,89,NaN]	5	hSpCas9	negative selection	10009538
100818600	100818623	7	+	27869803	HPAFII	viability after 31 days	TGGGTGAGGACCGCGTCACCCGG	EPHB4	ENSG00000196411	-0.9929846843124024	[213]	[67,51,NaN]	-6	hSpCas9	negative selection	10091983
100819556	100819579	7	-	27869803	HPAFII	viability after 31 days	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-1.9070334784577194	[419]	[25,102,NaN]	-8	hSpCas9	negative selection	10091984
100822353	100822376	7	+	27869803	HPAFII	viability after 31 days	ATCCTCACGGCAGTAGAGGCTGG	EPHB4	ENSG00000196411	0.2315317717997566	[116]	[67,86,NaN]	1	hSpCas9	negative selection	10091985
100823682	100823705	7	-	27869803	HPAFII	viability after 31 days	GAGCGATGCGGACACGGCCACGG	EPHB4	ENSG00000196411	0.6609431557402096	[187]	[173,158,NaN]	5	hSpCas9	negative selection	10091986
100824202	100824225	7	-	27869803	HPAFII	viability after 31 days	ATTCCCTCAGGTGGACGGGCAGG	EPHB4	ENSG00000196411	1.1921645883144825	[67]	[46,130,NaN]	8	hSpCas9	negative selection	10091987
100823812	100823835	7	-	28162770	P31FUJ	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-1.10727132233052	[131]	[71]	-6	hSpCas9	negative selection	10150625
100807570	100807593	7	-	28162770	P31FUJ	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	0.11562369265005967	[204]	[260]	1	hSpCas9	negative selection	10150626
100822270	100822293	7	-	28162770	P31FUJ	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-1.8177647051355352	[38]	[12]	-8	hSpCas9	negative selection	10150627
100822649	100822672	7	-	28162770	P31FUJ	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.9557384751952807	[153]	[350]	9	hSpCas9	negative selection	10150628
100820140	100820163	7	+	28162770	P31FUJ	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.31621359990038606	[148]	[217]	3	hSpCas9	negative selection	10150629
100819867	100819890	7	+	28162770	P31FUJ	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	0.5092612573915065	[112]	[188]	6	hSpCas9	negative selection	10150630
100819836	100819859	7	+	28162770	P31FUJ	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.47737054386528344	[249]	[408]	5	hSpCas9	negative selection	10150631
100819556	100819579	7	-	28162770	P31FUJ	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.04189221859199238	[266]	[322]	0	hSpCas9	negative selection	10150632
100812910	100812933	7	-	28162770	P31FUJ	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.5665599268896948	[180]	[314]	6	hSpCas9	negative selection	10150633
100812735	100812758	7	+	28162770	P31FUJ	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	-1.0499381472645681	[110]	[62]	-6	hSpCas9	negative selection	10150634
100823812	100823835	7	-	28162770	TF1	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10319991
100807570	100807593	7	-	28162770	TF1	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10319992
100822270	100822293	7	-	28162770	TF1	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10319993
100822649	100822672	7	-	28162770	TF1	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	NaN	[NaN]	[351]	1	hSpCas9	negative selection	10319994
100820140	100820163	7	+	28162770	TF1	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	NaN	[NaN]	[301]	1	hSpCas9	negative selection	10319995
100819867	100819890	7	+	28162770	TF1	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10319996
100819836	100819859	7	+	28162770	TF1	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10319997
100819556	100819579	7	-	28162770	TF1	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10319998
100812910	100812933	7	-	28162770	TF1	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	NaN	[NaN]	[175]	1	hSpCas9	negative selection	10319999
100812735	100812758	7	+	28162770	TF1	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10320000
100823812	100823835	7	-	28162770	SKM1	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.39136734369214304	[45]	[61]	-3	hSpCas9	negative selection	10489357
100807570	100807593	7	-	28162770	SKM1	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-1.0048657551718159	[41]	[36]	-6	hSpCas9	negative selection	10489358
100822270	100822293	7	-	28162770	SKM1	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	0.3909920253121928	[21]	[50]	4	hSpCas9	negative selection	10489359
100822649	100822672	7	-	28162770	SKM1	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.512982549690803	[43]	[110]	5	hSpCas9	negative selection	10489360
100820140	100820163	7	+	28162770	SKM1	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	1.4823323368506185	[32]	[162]	9	hSpCas9	negative selection	10489361
100819867	100819890	7	+	28162770	SKM1	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-1.9740047914670555	[39]	[17]	-8	hSpCas9	negative selection	10489362
100819836	100819859	7	+	28162770	SKM1	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.2961797283263087	[81]	[177]	3	hSpCas9	negative selection	10489363
100819556	100819579	7	-	28162770	SKM1	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.8462492442686829	[59]	[58]	-6	hSpCas9	negative selection	10489364
100812910	100812933	7	-	28162770	SKM1	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.7629608026991506	[44]	[134]	7	hSpCas9	negative selection	10489365
100812735	100812758	7	+	28162770	SKM1	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.4999263968653571	[11]	[29]	5	hSpCas9	negative selection	10489366
100823812	100823835	7	-	28162770	SKM1	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.39136734369214304	[45]	[61]	-3	hSpCas9	negative selection	10658723
100807570	100807593	7	-	28162770	SKM1	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-1.0048657551718159	[41]	[36]	-6	hSpCas9	negative selection	10658724
100822270	100822293	7	-	28162770	SKM1	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	0.3909920253121928	[21]	[50]	4	hSpCas9	negative selection	10658725
100822649	100822672	7	-	28162770	SKM1	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.512982549690803	[43]	[110]	5	hSpCas9	negative selection	10658726
100820140	100820163	7	+	28162770	SKM1	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	1.4823323368506185	[32]	[162]	9	hSpCas9	negative selection	10658727
100819867	100819890	7	+	28162770	SKM1	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-1.9740047914670555	[39]	[17]	-8	hSpCas9	negative selection	10658728
100819836	100819859	7	+	28162770	SKM1	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.2961797283263087	[81]	[177]	3	hSpCas9	negative selection	10658729
100819556	100819579	7	-	28162770	SKM1	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.8462492442686829	[59]	[58]	-6	hSpCas9	negative selection	10658730
100812910	100812933	7	-	28162770	SKM1	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.7629608026991506	[44]	[134]	7	hSpCas9	negative selection	10658731
100812735	100812758	7	+	28162770	SKM1	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.4999263968653571	[11]	[29]	5	hSpCas9	negative selection	10658732
100823812	100823835	7	-	28162770	PL21	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.02225280684712788	[146]	[62]	0	hSpCas9	negative selection	10828089
100807570	100807593	7	-	28162770	PL21	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.07598479078491743	[154]	[63]	0	hSpCas9	negative selection	10828090
100822270	100822293	7	-	28162770	PL21	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-4.58122009903534	[54]	[0]	-9	hSpCas9	negative selection	10828091
100822649	100822672	7	-	28162770	PL21	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	-1.2693456688119	[143]	[25]	-7	hSpCas9	negative selection	10828092
100820140	100820163	7	+	28162770	PL21	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.9804615778499081	[176]	[151]	7	hSpCas9	negative selection	10828093
100819867	100819890	7	+	28162770	PL21	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-1.7287772874491973	[98]	[12]	-8	hSpCas9	negative selection	10828094
100819836	100819859	7	+	28162770	PL21	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	-0.30639623927501974	[178]	[62]	-2	hSpCas9	negative selection	10828095
100819556	100819579	7	-	28162770	PL21	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.14794340336389158	[196]	[94]	1	hSpCas9	negative selection	10828096
100812910	100812933	7	-	28162770	PL21	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	-0.3458287546159724	[145]	[49]	-2	hSpCas9	negative selection	10828097
100812735	100812758	7	+	28162770	PL21	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	-1.2852872126809216	[55]	[9]	-7	hSpCas9	negative selection	10828098
100823812	100823835	7	-	28162770	P31FUJ	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-1.10727132233052	[131]	[71]	-6	hSpCas9	negative selection	10997455
100807570	100807593	7	-	28162770	P31FUJ	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	0.11562369265005967	[204]	[260]	1	hSpCas9	negative selection	10997456
100822270	100822293	7	-	28162770	P31FUJ	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-1.8177647051355352	[38]	[12]	-8	hSpCas9	negative selection	10997457
100822649	100822672	7	-	28162770	P31FUJ	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.9557384751952807	[153]	[350]	9	hSpCas9	negative selection	10997458
100820140	100820163	7	+	28162770	P31FUJ	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.31621359990038606	[148]	[217]	3	hSpCas9	negative selection	10997459
100819867	100819890	7	+	28162770	P31FUJ	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	0.5092612573915065	[112]	[188]	6	hSpCas9	negative selection	10997460
100819836	100819859	7	+	28162770	P31FUJ	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.47737054386528344	[249]	[408]	5	hSpCas9	negative selection	10997461
100819556	100819579	7	-	28162770	P31FUJ	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.04189221859199238	[266]	[322]	0	hSpCas9	negative selection	10997462
100812910	100812933	7	-	28162770	P31FUJ	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.5665599268896948	[180]	[314]	6	hSpCas9	negative selection	10997463
100812735	100812758	7	+	28162770	P31FUJ	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	-1.0499381472645681	[110]	[62]	-6	hSpCas9	negative selection	10997464
100823812	100823835	7	-	28162770	OCIAML5	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.8039722826629518	[58]	[60]	-5	hSpCas9	negative selection	11166821
100807570	100807593	7	-	28162770	OCIAML5	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.15973397262618938	[150]	[243]	-1	hSpCas9	negative selection	11166822
100822270	100822293	7	-	28162770	OCIAML5	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-0.7849523750054601	[20]	[21]	-5	hSpCas9	negative selection	11166823
100822649	100822672	7	-	28162770	OCIAML5	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.5720731355220994	[78]	[211]	5	hSpCas9	negative selection	11166824
100820140	100820163	7	+	28162770	OCIAML5	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.94544056523726	[41]	[145]	7	hSpCas9	negative selection	11166825
100819867	100819890	7	+	28162770	OCIAML5	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-0.13585953686458807	[69]	[114]	-1	hSpCas9	negative selection	11166826
100819836	100819859	7	+	28162770	OCIAML5	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.721755372251959	[129]	[386]	6	hSpCas9	negative selection	11166827
100819556	100819579	7	-	28162770	OCIAML5	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.4199362986916831	[146]	[354]	3	hSpCas9	negative selection	11166828
100812910	100812933	7	-	28162770	OCIAML5	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.38210301824880455	[121]	[286]	3	hSpCas9	negative selection	11166829
100812735	100812758	7	+	28162770	OCIAML5	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.9237182721927374	[65]	[225]	7	hSpCas9	negative selection	11166830
100823812	100823835	7	-	28162770	EOL1	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	0.2912222492879794	[272]	[175]	2	hSpCas9	negative selection	11336187
100807570	100807593	7	-	28162770	EOL1	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	0.7587388786004542	[174]	[155]	6	hSpCas9	negative selection	11336188
100822270	100822293	7	-	28162770	EOL1	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	0.6692907163284599	[110]	[92]	6	hSpCas9	negative selection	11336189
100822649	100822672	7	-	28162770	EOL1	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.30389356370606946	[265]	[172]	2	hSpCas9	negative selection	11336190
100820140	100820163	7	+	28162770	EOL1	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.6913485952775038	[334]	[284]	6	hSpCas9	negative selection	11336191
100819867	100819890	7	+	28162770	EOL1	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-0.011887099651999466	[221]	[115]	0	hSpCas9	negative selection	11336192
100819836	100819859	7	+	28162770	EOL1	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	-0.4180538915815777	[245]	[96]	-3	hSpCas9	negative selection	11336193
100819556	100819579	7	-	28162770	EOL1	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.6604861709330129	[280]	[233]	6	hSpCas9	negative selection	11336194
100812910	100812933	7	-	28162770	EOL1	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.15764489325022463	[210]	[123]	1	hSpCas9	negative selection	11336195
100812735	100812758	7	+	28162770	EOL1	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	1.7585378201316053	[114]	[204]	9	hSpCas9	negative selection	11336196
100823812	100823835	7	-	28162770	MOLM13	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.1739755104110542	[180]	[115]	-1	hSpCas9	negative selection	11505553
100807570	100807593	7	-	28162770	MOLM13	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.4711095463234961	[300]	[156]	-3	hSpCas9	negative selection	11505554
100822270	100822293	7	-	28162770	MOLM13	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	0.4089956924910103	[49]	[47]	3	hSpCas9	negative selection	11505555
100822649	100822672	7	-	28162770	MOLM13	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.3931920142669778	[217]	[206]	3	hSpCas9	negative selection	11505556
100820140	100820163	7	+	28162770	MOLM13	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	1.3505324309064202	[191]	[353]	8	hSpCas9	negative selection	11505557
100819867	100819890	7	+	28162770	MOLM13	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	0.13038848273675518	[162]	[128]	0	hSpCas9	negative selection	11505558
100819836	100819859	7	+	28162770	MOLM13	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.2802623783688074	[245]	[215]	2	hSpCas9	negative selection	11505559
100819556	100819579	7	-	28162770	MOLM13	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.5702457473421922	[459]	[223]	-3	hSpCas9	negative selection	11505560
100812910	100812933	7	-	28162770	MOLM13	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	-0.8468071441117075	[198]	[79]	-5	hSpCas9	negative selection	11505561
100812735	100812758	7	+	28162770	MOLM13	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	-1.312329410575511	[78]	[22]	-6	hSpCas9	negative selection	11505562
100823812	100823835	7	-	28162770	HEL	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	0.12939925910970929	[166]	[116]	1	hSpCas9	negative selection	11674919
100807570	100807593	7	-	28162770	HEL	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-1.1937624357167635	[249]	[69]	-6	hSpCas9	negative selection	11674920
100822270	100822293	7	-	28162770	HEL	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-0.942223668720799	[53]	[17]	-5	hSpCas9	negative selection	11674921
100822649	100822672	7	-	28162770	HEL	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	1.2894303224732193	[121]	[190]	9	hSpCas9	negative selection	11674922
100820140	100820163	7	+	28162770	HEL	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.5642647739772724	[169]	[160]	5	hSpCas9	negative selection	11674923
100819867	100819890	7	+	28162770	HEL	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	0.7526164497727305	[138]	[149]	6	hSpCas9	negative selection	11674924
100819836	100819859	7	+	28162770	HEL	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.21180995995162163	[212]	[157]	1	hSpCas9	negative selection	11674925
100819556	100819579	7	-	28162770	HEL	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.6621157495280638	[335]	[135]	-4	hSpCas9	negative selection	11674926
100812910	100812933	7	-	28162770	HEL	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.7323760444850336	[155]	[165]	6	hSpCas9	negative selection	11674927
100812735	100812758	7	+	28162770	HEL	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.6135924863408404	[99]	[97]	5	hSpCas9	negative selection	11674928
100823812	100823835	7	-	28162770	MV411	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	0.7401415436519432	[112]	[158]	6	hSpCas9	negative selection	11844285
100807570	100807593	7	-	28162770	MV411	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.4193190411020281	[126]	[79]	-3	hSpCas9	negative selection	11844286
100822270	100822293	7	-	28162770	MV411	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-1.7800431856393317	[52]	[12]	-8	hSpCas9	negative selection	11844287
100822649	100822672	7	-	28162770	MV411	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.5170446105400555	[145]	[175]	4	hSpCas9	negative selection	11844288
100820140	100820163	7	+	28162770	MV411	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	1.0679897752219565	[170]	[301]	8	hSpCas9	negative selection	11844289
100819867	100819890	7	+	28162770	MV411	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-0.7649461736730572	[116]	[57]	-5	hSpCas9	negative selection	11844290
100819836	100819859	7	+	28162770	MV411	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	1.080327564947517	[191]	[341]	8	hSpCas9	negative selection	11844291
100819556	100819579	7	-	28162770	MV411	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.437009794675548	[234]	[267]	4	hSpCas9	negative selection	11844292
100812910	100812933	7	-	28162770	MV411	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.4501223007017373	[178]	[205]	4	hSpCas9	negative selection	11844293
100812735	100812758	7	+	28162770	MV411	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.8100322384754769	[64]	[95]	7	hSpCas9	negative selection	11844294
100823812	100823835	7	-	28162770	MONOMAC1	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.4794365777602786	[89]	[73]	-4	hSpCas9	negative selection	12013651
100807570	100807593	7	-	28162770	MONOMAC1	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.2313883518503308	[84]	[82]	-2	hSpCas9	negative selection	12013652
100822270	100822293	7	-	28162770	MONOMAC1	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	2.403867197530624	[29]	[181]	9	hSpCas9	negative selection	12013653
100822649	100822672	7	-	28162770	MONOMAC1	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	-0.6799784108402012	[115]	[82]	-5	hSpCas9	negative selection	12013654
100820140	100820163	7	+	28162770	MONOMAC1	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	1.0734920953211646	[79]	[192]	8	hSpCas9	negative selection	12013655
100819867	100819890	7	+	28162770	MONOMAC1	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-0.44214934489608526	[63]	[53]	-4	hSpCas9	negative selection	12013656
100819836	100819859	7	+	28162770	MONOMAC1	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.9487047863892066	[126]	[280]	8	hSpCas9	negative selection	12013657
100819556	100819579	7	-	28162770	MONOMAC1	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.41242588065823915	[136]	[117]	-4	hSpCas9	negative selection	12013658
100812910	100812933	7	-	28162770	MONOMAC1	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.828803157875706	[82]	[168]	7	hSpCas9	negative selection	12013659
100812735	100812758	7	+	28162770	MONOMAC1	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	-0.15521667136492678	[33]	[34]	-1	hSpCas9	negative selection	12013660
100823812	100823835	7	-	28162770	OCIAML2	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.3413468082971949	[23]	[104]	-3	hSpCas9	negative selection	12183017
100807570	100807593	7	-	28162770	OCIAML2	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	0.9830881422007425	[22]	[251]	8	hSpCas9	negative selection	12183018
100822270	100822293	7	-	28162770	OCIAML2	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-0.9345769250019513	[9]	[28]	-6	hSpCas9	negative selection	12183019
100822649	100822672	7	-	28162770	OCIAML2	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	1.3107298882824985	[19]	[274]	9	hSpCas9	negative selection	12183020
100820140	100820163	7	+	28162770	OCIAML2	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	-0.09211820198843142	[34]	[181]	-1	hSpCas9	negative selection	12183021
100819867	100819890	7	+	28162770	OCIAML2	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-0.05029802629380442	[16]	[90]	0	hSpCas9	negative selection	12183022
100819836	100819859	7	+	28162770	OCIAML2	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.7924045805916327	[34]	[335]	7	hSpCas9	negative selection	12183023
100819556	100819579	7	-	28162770	OCIAML2	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	0.11903967815652261	[50]	[306]	1	hSpCas9	negative selection	12183024
100812910	100812933	7	-	28162770	OCIAML2	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	-0.2792037545889267	[36]	[168]	-2	hSpCas9	negative selection	12183025
100812735	100812758	7	+	28162770	OCIAML2	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	0.11433267547899506	[10]	[65]	1	hSpCas9	negative selection	12183026
100823812	100823835	7	-	28162770	OCIAML3	viability	GCACAGGTTGGGTCCCACGGCGG	EPHB4	ENSG00000196411	-0.09924294857458527	[43]	[123]	-1	hSpCas9	negative selection	12352383
100807570	100807593	7	-	28162770	OCIAML3	viability	TCTGCTCTCCAGCTAAACGACGG	EPHB4	ENSG00000196411	-0.9992641188104215	[48]	[73]	-6	hSpCas9	negative selection	12352384
100822270	100822293	7	-	28162770	OCIAML3	viability	GAGGGGAACACCAAGTGCCGAGG	EPHB4	ENSG00000196411	-0.1159603435195189	[13]	[38]	-1	hSpCas9	negative selection	12352385
100822649	100822672	7	-	28162770	OCIAML3	viability	GCAGGTGGACACGGTGGCCGCGG	EPHB4	ENSG00000196411	0.3946770464480026	[31]	[126]	3	hSpCas9	negative selection	12352386
100820140	100820163	7	+	28162770	OCIAML3	viability	CTGGTGCAGGGTGCACCCCGGGG	EPHB4	ENSG00000196411	0.6394824898956154	[36]	[173]	6	hSpCas9	negative selection	12352387
100819867	100819890	7	+	28162770	OCIAML3	viability	GCTCCGCGGAGCCGAAGGAGGGG	EPHB4	ENSG00000196411	-1.0611336507514613	[46]	[67]	-6	hSpCas9	negative selection	12352388
100819836	100819859	7	+	28162770	OCIAML3	viability	GCAGGGAGGAGCCGTTCAGGCGG	EPHB4	ENSG00000196411	0.9838654356106737	[67]	[405]	8	hSpCas9	negative selection	12352389
100819556	100819579	7	-	28162770	OCIAML3	viability	AATGTCACCACTGACCGAGAGGG	EPHB4	ENSG00000196411	-0.25297072248909624	[44]	[113]	-2	hSpCas9	negative selection	12352390
100812910	100812933	7	-	28162770	OCIAML3	viability	GCAATCAAGACCCTGAAGGGTGG	EPHB4	ENSG00000196411	0.03114395051269181	[58]	[181]	0	hSpCas9	negative selection	12352391
100812735	100812758	7	+	28162770	OCIAML3	viability	GAGGGTGCTCACCCGCAGGAAGG	EPHB4	ENSG00000196411	-0.1345760216868659	[19]	[54]	-1	hSpCas9	negative selection	12352392