Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:79574
• Symbol:EPS8L3
• Description:EPS8 like 3

DataSource: http://genomecrispr.dkfz.de/#!/results/EPS8L3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
109761512	109761535	1	+	26472758	Jiyoye	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-1.528694281074411	[87]	[22]	-7	hSpCas9	negative selection	51216
109757039	109757062	1	-	26472758	Jiyoye	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	0.6136262589732997	[12]	[14]	4	hSpCas9	negative selection	51217
109759795	109759818	1	-	26472758	Jiyoye	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	0.6295678028423213	[11]	[13]	4	hSpCas9	negative selection	51218
109759069	109759092	1	-	26472758	Jiyoye	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	51219
109758389	109758412	1	+	26472758	Jiyoye	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	2.0123723659670834	[117]	[358]	8	hSpCas9	negative selection	51220
109758341	109758364	1	+	26472758	Jiyoye	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	0.9307373375628862	[127]	[183]	6	hSpCas9	negative selection	51221
109757995	109758018	1	-	26472758	Jiyoye	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-0.6192968298553174	[54]	[26]	-4	hSpCas9	negative selection	51222
109752015	109752038	1	-	26472758	Jiyoye	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-3.8407521319377125	[18]	[0]	-9	hSpCas9	negative selection	51223
109751737	109751760	1	-	26472758	Jiyoye	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-2.21731548340192	[110]	[17]	-8	hSpCas9	negative selection	51224
109758537	109758560	1	-	26472758	Jiyoye	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.11243211594474145	[275]	[224]	0	hSpCas9	negative selection	51225
109761512	109761535	1	+	26472758	KBM7	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-2.846408925035846	[133,77]	[10,2]	-9	hSpCas9	negative selection	242334
109757039	109757062	1	-	26472758	KBM7	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-0.07289140677521244	[59,104]	[26,47]	0	hSpCas9	negative selection	242335
109759795	109759818	1	-	26472758	KBM7	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-0.39772389504997574	[307,134]	[70,80]	-4	hSpCas9	negative selection	242336
109759069	109759092	1	-	26472758	KBM7	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	1.0816969781589814	[0,0]	[0,0]	9	hSpCas9	negative selection	242337
109758389	109758412	1	+	26472758	KBM7	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.3327799789462025	[1754,1247]	[1026,744]	3	hSpCas9	negative selection	242338
109758341	109758364	1	+	26472758	KBM7	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	0.3062498307963093	[797,470]	[323,393]	3	hSpCas9	negative selection	242339
109757995	109758018	1	-	26472758	KBM7	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-1.0514509422558977	[339,240]	[91,40]	-7	hSpCas9	negative selection	242340
109752015	109752038	1	-	26472758	KBM7	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-0.8494341429450176	[25,38]	[4,11]	-6	hSpCas9	negative selection	242341
109751737	109751760	1	-	26472758	KBM7	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-2.7640399110782727	[557,648]	[64,21]	-9	hSpCas9	negative selection	242342
109758537	109758560	1	-	26472758	KBM7	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.5054818749526522	[628,476]	[370,360]	5	hSpCas9	negative selection	242343
109761512	109761535	1	+	26472758	Raji	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-0.6088234986258096	[45]	[6]	-5	hSpCas9	negative selection	433452
109757039	109757062	1	-	26472758	Raji	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-1.232466467511025	[80]	[7]	-7	hSpCas9	negative selection	433453
109759795	109759818	1	-	26472758	Raji	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	0.6282156986750401	[91]	[32]	6	hSpCas9	negative selection	433454
109759069	109759092	1	-	26472758	Raji	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	433455
109758389	109758412	1	+	26472758	Raji	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.14928469083535423	[508]	[130]	1	hSpCas9	negative selection	433456
109758341	109758364	1	+	26472758	Raji	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	-0.38615593758396183	[320]	[56]	-3	hSpCas9	negative selection	433457
109757995	109758018	1	-	26472758	Raji	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-1.8678130736258276	[172]	[10]	-8	hSpCas9	negative selection	433458
109752015	109752038	1	-	26472758	Raji	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	2.6219567082033572	[6]	[9]	9	hSpCas9	negative selection	433459
109751737	109751760	1	-	26472758	Raji	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-2.1285047284470715	[357]	[18]	-8	hSpCas9	negative selection	433460
109758537	109758560	1	-	26472758	Raji	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.63847916411602	[381]	[137]	6	hSpCas9	negative selection	433461
109761512	109761535	1	+	26472758	K562	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-1.2355742134531673	[52]	[18]	-6	hSpCas9	negative selection	624570
109757039	109757062	1	-	26472758	K562	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-0.9555188428423049	[84]	[36]	-5	hSpCas9	negative selection	624571
109759795	109759818	1	-	26472758	K562	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-6.755581272333552	[127]	[0]	-9	hSpCas9	negative selection	624572
109759069	109759092	1	-	26472758	K562	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-3.3405437730547085	[11]	[0]	-8	hSpCas9	negative selection	624573
109758389	109758412	1	+	26472758	K562	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	-0.7873141831914487	[1332]	[651]	-5	hSpCas9	negative selection	624574
109758341	109758364	1	+	26472758	K562	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	-1.1794475309871344	[600]	[223]	-6	hSpCas9	negative selection	624575
109757995	109758018	1	-	26472758	K562	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-4.700439718141093	[153]	[4]	-9	hSpCas9	negative selection	624576
109752015	109752038	1	-	26472758	K562	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-0.06873915759318372	[40]	[32]	0	hSpCas9	negative selection	624577
109751737	109751760	1	-	26472758	K562	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-2.320365891117079	[638]	[107]	-8	hSpCas9	negative selection	624578
109758537	109758560	1	-	26472758	K562	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.715943418291764	[431]	[598]	6	hSpCas9	negative selection	624579
109757480	109757503	1	+	26627737	DLD1	viability	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.3283562798114259	[637]	[364,264,138]	3	hSpCas9	negative selection	764786
109758383	109758406	1	+	26627737	DLD1	viability	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.18917593561314205	[844]	[289,376,247]	2	hSpCas9	negative selection	764788
109758580	109758603	1	+	26627737	DLD1	viability	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.036307463096133974	[1319]	[358,423,477]	0	hSpCas9	negative selection	764789
109759288	109759311	1	+	26627737	DLD1	viability	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.41958558922263167	[369]	[156,163,144]	4	hSpCas9	negative selection	764790
109759752	109759775	1	-	26627737	DLD1	viability	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.4866850875313312	[452]	[370,161,78]	5	hSpCas9	negative selection	764791
109761548	109761571	1	-	26627737	DLD1	viability	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.20110001343694742	[361]	[100,156,132]	2	hSpCas9	negative selection	764792
109757480	109757503	1	+	26627737	GBM cells	viability after 5 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	-0.07487624579146579	[599]	[293,316]	-1	hSpCas9	negative selection	847101
109758383	109758406	1	+	26627737	GBM cells	viability after 5 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.8190100092934718	[231]	[255,182]	9	hSpCas9	negative selection	847103
109758580	109758603	1	+	26627737	GBM cells	viability after 5 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.3462023104487184	[563]	[415,352]	5	hSpCas9	negative selection	847104
109759288	109759311	1	+	26627737	GBM cells	viability after 5 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.6358794690518919	[134]	[132,91]	8	hSpCas9	negative selection	847105
109759752	109759775	1	-	26627737	GBM cells	viability after 5 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.2525508295003862	[107]	[88,48]	4	hSpCas9	negative selection	847106
109761548	109761571	1	-	26627737	GBM cells	viability after 5 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.596179345231634	[139]	[127,98]	8	hSpCas9	negative selection	847107
109757480	109757503	1	+	26627737	GBM cells	viability after 13 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	-0.0482486186367983	[599]	[337,295]	0	hSpCas9	negative selection	929416
109758383	109758406	1	+	26627737	GBM cells	viability after 13 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	1.1344135114032325	[231]	[261,287]	9	hSpCas9	negative selection	929418
109758580	109758603	1	+	26627737	GBM cells	viability after 13 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.416692101784484	[563]	[488,342]	5	hSpCas9	negative selection	929419
109759288	109759311	1	+	26627737	GBM cells	viability after 13 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.3647208548012377	[134]	[106,83]	4	hSpCas9	negative selection	929420
109759752	109759775	1	-	26627737	GBM cells	viability after 13 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.14990979911870572	[107]	[96,38]	2	hSpCas9	negative selection	929421
109761548	109761571	1	-	26627737	GBM cells	viability after 13 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.24914521988547855	[139]	[97,83]	3	hSpCas9	negative selection	929422
109757480	109757503	1	+	26627737	GBM cells	viability after 21 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.17576042558232152	[599]	[386,350]	1	hSpCas9	negative selection	1011731
109758383	109758406	1	+	26627737	GBM cells	viability after 21 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	1.072100853938648	[231]	[264,264]	9	hSpCas9	negative selection	1011733
109758580	109758603	1	+	26627737	GBM cells	viability after 21 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.2650277636794087	[563]	[386,350]	2	hSpCas9	negative selection	1011734
109759288	109759311	1	+	26627737	GBM cells	viability after 21 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.47033206087123164	[134]	[98,103]	5	hSpCas9	negative selection	1011735
109759752	109759775	1	-	26627737	GBM cells	viability after 21 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.2272757281581319	[107]	[58,41]	-2	hSpCas9	negative selection	1011736
109761548	109761571	1	-	26627737	GBM cells	viability after 21 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	-0.19328525875618074	[139]	[65,66]	-2	hSpCas9	negative selection	1011737
109757480	109757503	1	+	26627737	RPE1	viability after 9 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.24551177898382903	[1413]	[457,610]	1	hSpCas9	negative selection	1094046
109758383	109758406	1	+	26627737	RPE1	viability after 9 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.04729231075592	[1561]	[379,666]	0	hSpCas9	negative selection	1094048
109758580	109758603	1	+	26627737	RPE1	viability after 9 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.38610955981173656	[1902]	[699,879]	2	hSpCas9	negative selection	1094049
109759288	109759311	1	+	26627737	RPE1	viability after 9 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-0.8289545615183032	[541]	[167,1]	-5	hSpCas9	negative selection	1094050
109759752	109759775	1	-	26627737	RPE1	viability after 9 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.12172029775429621	[573]	[81,341]	0	hSpCas9	negative selection	1094051
109761548	109761571	1	-	26627737	RPE1	viability after 9 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	2.2966330985370877	[100]	[205,89]	9	hSpCas9	negative selection	1094052
109757480	109757503	1	+	26627737	RPE1	viability after 12 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.49524928383795475	[1413]	[415,661]	3	hSpCas9	negative selection	1176361
109758383	109758406	1	+	26627737	RPE1	viability after 12 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.0028456500425317888	[1561]	[402,438]	0	hSpCas9	negative selection	1176363
109758580	109758603	1	+	26627737	RPE1	viability after 12 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.47244897903531524	[1902]	[687,731]	3	hSpCas9	negative selection	1176364
109759288	109759311	1	+	26627737	RPE1	viability after 12 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-0.24084464589119992	[541]	[198,42]	-2	hSpCas9	negative selection	1176365
109759752	109759775	1	-	26627737	RPE1	viability after 12 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.15341738718331843	[573]	[109,168]	-1	hSpCas9	negative selection	1176366
109761548	109761571	1	-	26627737	RPE1	viability after 12 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	2.315936338434181	[100]	[138,130]	9	hSpCas9	negative selection	1176367
109757480	109757503	1	+	26627737	RPE1	viability after 15 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.30071898127851404	[1413]	[481,502]	2	hSpCas9	negative selection	1258676
109758383	109758406	1	+	26627737	RPE1	viability after 15 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.41016043554824566	[1561]	[387,278]	-3	hSpCas9	negative selection	1258678
109758580	109758603	1	+	26627737	RPE1	viability after 15 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.2205103274970166	[1902]	[614,638]	1	hSpCas9	negative selection	1258679
109759288	109759311	1	+	26627737	RPE1	viability after 15 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-0.334755109960716	[541]	[201,43]	-2	hSpCas9	negative selection	1258680
109759752	109759775	1	-	26627737	RPE1	viability after 15 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.25363267652480004	[573]	[68,200]	-1	hSpCas9	negative selection	1258681
109761548	109761571	1	-	26627737	RPE1	viability after 15 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	2.697193047712794	[100]	[196,173]	9	hSpCas9	negative selection	1258682
109757480	109757503	1	+	26627737	RPE1	viability after 18 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.007924336165831103	[1413]	[199,579]	0	hSpCas9	negative selection	1340991
109758383	109758406	1	+	26627737	RPE1	viability after 18 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.26243113821006114	[1561]	[290,415]	-2	hSpCas9	negative selection	1340993
109758580	109758603	1	+	26627737	RPE1	viability after 18 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.3503957046298023	[1902]	[588,724]	2	hSpCas9	negative selection	1340994
109759288	109759311	1	+	26627737	RPE1	viability after 18 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-0.3386317251580907	[541]	[105,125]	-2	hSpCas9	negative selection	1340995
109759752	109759775	1	-	26627737	RPE1	viability after 18 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.040350913513532205	[573]	[65,258]	0	hSpCas9	negative selection	1340996
109761548	109761571	1	-	26627737	RPE1	viability after 18 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	2.768334647205741	[100]	[249,116]	9	hSpCas9	negative selection	1340997
109757480	109757503	1	+	26627737	HeLa	viability after 8 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.5534340126910962	[640]	[444,353,434]	5	hSpCas9	negative selection	1423306
109758383	109758406	1	+	26627737	HeLa	viability after 8 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.5258986504634008	[711]	[549,555,267]	5	hSpCas9	negative selection	1423308
109758580	109758603	1	+	26627737	HeLa	viability after 8 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.8356972957407807	[692]	[373,689,515]	7	hSpCas9	negative selection	1423309
109759288	109759311	1	+	26627737	HeLa	viability after 8 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-0.8861482964664174	[324]	[50,52,116]	-7	hSpCas9	negative selection	1423310
109759752	109759775	1	-	26627737	HeLa	viability after 8 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.057682868526578196	[341]	[89,273,90]	0	hSpCas9	negative selection	1423311
109761548	109761571	1	-	26627737	HeLa	viability after 8 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.6122249517906748	[118]	[95,107,39]	5	hSpCas9	negative selection	1423312
109757480	109757503	1	+	26627737	HeLa	viability after 12 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.2125230098197689	[640]	[377,239,311]	2	hSpCas9	negative selection	1505621
109758383	109758406	1	+	26627737	HeLa	viability after 12 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.22227372786313138	[711]	[458,202,385]	2	hSpCas9	negative selection	1505623
109758580	109758603	1	+	26627737	HeLa	viability after 12 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.9216968760092017	[692]	[570,602,447]	7	hSpCas9	negative selection	1505624
109759288	109759311	1	+	26627737	HeLa	viability after 12 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-0.10508648576635748	[324]	[195,121,58]	-1	hSpCas9	negative selection	1505625
109759752	109759775	1	-	26627737	HeLa	viability after 12 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.6828278988641252	[341]	[90,108,61]	-6	hSpCas9	negative selection	1505626
109761548	109761571	1	-	26627737	HeLa	viability after 12 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	1.5963707538377674	[118]	[143,157,142]	9	hSpCas9	negative selection	1505627
109757480	109757503	1	+	26627737	HeLa	viability after 15 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	-0.13120576373089432	[640]	[267,176,271]	-1	hSpCas9	negative selection	1587936
109758383	109758406	1	+	26627737	HeLa	viability after 15 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.7286925797197834	[711]	[202,138,182]	-6	hSpCas9	negative selection	1587938
109758580	109758603	1	+	26627737	HeLa	viability after 15 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.6595533546604408	[692]	[506,384,443]	5	hSpCas9	negative selection	1587939
109759288	109759311	1	+	26627737	HeLa	viability after 15 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-1.3460650553254165	[324]	[75,73,1]	-8	hSpCas9	negative selection	1587940
109759752	109759775	1	-	26627737	HeLa	viability after 15 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.1741389626958256	[341]	[169,96,207]	1	hSpCas9	negative selection	1587941
109761548	109761571	1	-	26627737	HeLa	viability after 15 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	1.6694895205582732	[118]	[208,129,119]	9	hSpCas9	negative selection	1587942
109757480	109757503	1	+	26627737	HeLa	viability after 18 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	-0.13890800559527516	[640]	[172,151,271]	-1	hSpCas9	negative selection	1670251
109758383	109758406	1	+	26627737	HeLa	viability after 18 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.7029847155655964	[711]	[147,107,182]	-6	hSpCas9	negative selection	1670253
109758580	109758603	1	+	26627737	HeLa	viability after 18 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.6868995063665562	[692]	[342,335,443]	5	hSpCas9	negative selection	1670254
109759288	109759311	1	+	26627737	HeLa	viability after 18 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-1.4103605281504026	[324]	[49,56,1]	-8	hSpCas9	negative selection	1670255
109759752	109759775	1	-	26627737	HeLa	viability after 18 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.17923238905390312	[341]	[116,77,207]	1	hSpCas9	negative selection	1670256
109761548	109761571	1	-	26627737	HeLa	viability after 18 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	1.685061835786647	[118]	[139,111,119]	9	hSpCas9	negative selection	1670257
109757480	109757503	1	+	26627737	HCT116	viability after 6 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.4293842063336847	[892]	[141,214]	2	hSpCas9	negative selection	1752566
109758383	109758406	1	+	26627737	HCT116	viability after 6 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.0032325608742501677	[797]	[304,25]	0	hSpCas9	negative selection	1752568
109758580	109758603	1	+	26627737	HCT116	viability after 6 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	1.076469468736865	[1374]	[538,409]	6	hSpCas9	negative selection	1752569
109759288	109759311	1	+	26627737	HCT116	viability after 6 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.812837881351645	[592]	[117,188]	4	hSpCas9	negative selection	1752570
109759752	109759775	1	-	26627737	HCT116	viability after 6 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	1.157614434109332	[693]	[419,145]	6	hSpCas9	negative selection	1752571
109761548	109761571	1	-	26627737	HCT116	viability after 6 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.6562293413616026	[398]	[45,127]	3	hSpCas9	negative selection	1752572
109757480	109757503	1	+	26627737	HCT116	viability after 8 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.40423624021499505	[588]	[357,560,368]	4	hSpCas9	negative selection	1834881
109758383	109758406	1	+	26627737	HCT116	viability after 8 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.1080999654679975	[605]	[381,411,286]	1	hSpCas9	negative selection	1834883
109758580	109758603	1	+	26627737	HCT116	viability after 8 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	-0.4913172503254677	[1299]	[634,469,426]	-5	hSpCas9	negative selection	1834884
109759288	109759311	1	+	26627737	HCT116	viability after 8 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.9666770159238083	[95]	[126,115,67]	8	hSpCas9	negative selection	1834885
109759752	109759775	1	-	26627737	HCT116	viability after 8 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.7363239039376613	[334]	[111,155,64]	-7	hSpCas9	negative selection	1834886
109761548	109761571	1	-	26627737	HCT116	viability after 8 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	-1.063196537261311	[253]	[108,50,41]	-8	hSpCas9	negative selection	1834887
109757480	109757503	1	+	26627737	HCT116	viability after 9 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.4514407938719601	[892]	[563,137]	3	hSpCas9	negative selection	1917196
109758383	109758406	1	+	26627737	HCT116	viability after 9 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.5994912593678714	[797]	[390,268]	4	hSpCas9	negative selection	1917198
109758580	109758603	1	+	26627737	HCT116	viability after 9 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.39220476211515565	[1374]	[406,540]	3	hSpCas9	negative selection	1917199
109759288	109759311	1	+	26627737	HCT116	viability after 9 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.5939683247882135	[592]	[362,140]	4	hSpCas9	negative selection	1917200
109759752	109759775	1	-	26627737	HCT116	viability after 9 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.15635327334090718	[693]	[253,168]	1	hSpCas9	negative selection	1917201
109761548	109761571	1	-	26627737	HCT116	viability after 9 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	1.4342636552443007	[398]	[54,471]	8	hSpCas9	negative selection	1917202
109757480	109757503	1	+	26627737	HCT116	viability after 12 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.07238937785528843	[588]	[271,321,386]	0	hSpCas9	negative selection	1999511
109758383	109758406	1	+	26627737	HCT116	viability after 12 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.2708579202656778	[605]	[352,364,436]	2	hSpCas9	negative selection	1999513
109758580	109758603	1	+	26627737	HCT116	viability after 12 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	-0.3389762494101298	[1299]	[592,385,632]	-4	hSpCas9	negative selection	1999514
109759288	109759311	1	+	26627737	HCT116	viability after 12 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	1.4758495023999918	[95]	[109,154,158]	9	hSpCas9	negative selection	1999515
109759752	109759775	1	-	26627737	HCT116	viability after 12 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.07974602039549218	[334]	[281,99,105]	-1	hSpCas9	negative selection	1999516
109761548	109761571	1	-	26627737	HCT116	viability after 12 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	-0.3182063389861403	[253]	[71,95,155]	-3	hSpCas9	negative selection	1999517
109757480	109757503	1	+	26627737	HCT116	viability after 15 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.32612280474048494	[588]	[432,311,526]	3	hSpCas9	negative selection	2081826
109758383	109758406	1	+	26627737	HCT116	viability after 15 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.035345793302748785	[605]	[360,394,314]	0	hSpCas9	negative selection	2081828
109758580	109758603	1	+	26627737	HCT116	viability after 15 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	-0.6943328933972097	[1299]	[657,364,385]	-6	hSpCas9	negative selection	2081829
109759288	109759311	1	+	26627737	HCT116	viability after 15 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	2.0325314404658372	[95]	[146,201,316]	9	hSpCas9	negative selection	2081830
109759752	109759775	1	-	26627737	HCT116	viability after 15 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.40299592765555803	[334]	[273,103,74]	-4	hSpCas9	negative selection	2081831
109761548	109761571	1	-	26627737	HCT116	viability after 15 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	-0.6970526409162199	[253]	[28,100,131]	-6	hSpCas9	negative selection	2081832
109757480	109757503	1	+	26627737	HCT116	viability after 18 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.18354082399967675	[588]	[384,170,428]	1	hSpCas9	negative selection	2164141
109758383	109758406	1	+	26627737	HCT116	viability after 18 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.3671918230166109	[605]	[381,261,502]	3	hSpCas9	negative selection	2164143
109758580	109758603	1	+	26627737	HCT116	viability after 18 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	-0.7216114139981356	[1299]	[490,227,436]	-6	hSpCas9	negative selection	2164144
109759288	109759311	1	+	26627737	HCT116	viability after 18 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	1.3761798705163026	[95]	[89,50,229]	8	hSpCas9	negative selection	2164145
109759752	109759775	1	-	26627737	HCT116	viability after 18 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.010559290356747575	[334]	[244,128,107]	0	hSpCas9	negative selection	2164146
109761548	109761571	1	-	26627737	HCT116	viability after 18 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	-1.0565914200635491	[253]	[35,77,61]	-7	hSpCas9	negative selection	2164147
109759813	109759836	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTTGATGACATGCAAGCAGGGG	EPS8L3	ENSG00000198758	-0.14084420286973282	[2,2]	[3,0]	-2	hSpCas9	positive selection	2986163
109758576	109758599	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATAGCGTGCCTGCTCCATAGGG	EPS8L3	ENSG00000198758	0.006737551623336474	[3,3]	[4,1]	0	hSpCas9	positive selection	2986164
109761552	109761575	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGTGCCCTTGTAGTGCACCGG	EPS8L3	ENSG00000198758	-0.22125175434395	[3,3]	[1,2]	-3	hSpCas9	positive selection	2986165
109758349	109758372	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACTCTGCCTCCTCCAAGGCGG	EPS8L3	ENSG00000198758	-0.6706274399041993	[3,4]	[1,2]	-7	hSpCas9	positive selection	2986166
109759813	109759836	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTTGATGACATGCAAGCAGGGG	EPS8L3	ENSG00000198758	-0.5794439647522538	[2,2]	[1,0]	-7	hSpCas9	positive selection	3054021
109758576	109758599	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATAGCGTGCCTGCTCCATAGGG	EPS8L3	ENSG00000198758	0.11487574607605097	[3,3]	[4,1]	2	hSpCas9	positive selection	3054022
109761552	109761575	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGTGCCCTTGTAGTGCACCGG	EPS8L3	ENSG00000198758	0.29705412830560435	[3,3]	[3,1]	5	hSpCas9	positive selection	3054023
109758349	109758372	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACTCTGCCTCCTCCAAGGCGG	EPS8L3	ENSG00000198758	-0.1913934467443833	[3,3]	[2,1]	-3	hSpCas9	positive selection	3054024
109751325	109751348		-	24336571	A375	resistance to PLX after 7 days	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.1671710030004958	[37,36]	[33,31]	-5	hSpCas9	positive selection	3112339
109753184	109753207		-	24336571	A375	resistance to PLX after 7 days	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.08546418931966437	[44,38]	[41,45]	3	hSpCas9	positive selection	3112340
109753106	109753129		+	24336571	A375	resistance to PLX after 7 days	GCTCCCCTTACTTGGCTGGAGGG	EPS8L3	ENSG00000198758	0.09077241315733259	[16,16]	[16,18]	3	hSpCas9	positive selection	3112341
109753174	109753197		+	24336571	A375	resistance to PLX after 7 days	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	-0.09623797901237152	[37,35]	[34,32]	-3	hSpCas9	positive selection	3112342
109751325	109751348		-	24336571	A375	resistance to PLX after 14 days	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.35115621849632683	[42,38]	[14,14]	-4	hSpCas9	positive selection	3170132
109753184	109753207		-	24336571	A375	resistance to PLX after 14 days	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	-0.2430124299332912	[38,38]	[16,12]	-3	hSpCas9	positive selection	3170133
109753106	109753129		+	24336571	A375	resistance to PLX after 14 days	GCTCCCCTTACTTGGCTGGAGGG	EPS8L3	ENSG00000198758	-0.25687827541212255	[21,15]	[7,5]	-3	hSpCas9	positive selection	3170134
109753174	109753197		+	24336571	A375	resistance to PLX after 14 days	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.00944156867770296	[32,39]	[19,12]	0	hSpCas9	positive selection	3170135
109751325	109751348		-	24336571	A375	viability after 7 days	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.43507419846809703	[28]	[37,36]	6	hSpCas9	negative selection	3227925
109753184	109753207		-	24336571	A375	viability after 7 days	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.20839674694081833	[37]	[44,38]	3	hSpCas9	negative selection	3227926
109753106	109753129		+	24336571	A375	viability after 7 days	GCTCCCCTTACTTGGCTGGAGGG	EPS8L3	ENSG00000198758	0.01701642862834951	[16]	[16,16]	0	hSpCas9	negative selection	3227927
109753174	109753197		+	24336571	A375	viability after 7 days	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.5671342002064245	[25]	[37,35]	8	hSpCas9	negative selection	3227928
109751325	109751348		-	24336571	A375	viability after 14 days	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.584921536372331	[28]	[42,38]	7	hSpCas9	negative selection	3285718
109753184	109753207		-	24336571	A375	viability after 14 days	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.11803552751164337	[37]	[38,38]	1	hSpCas9	negative selection	3285719
109753106	109753129		+	24336571	A375	viability after 14 days	GCTCCCCTTACTTGGCTGGAGGG	EPS8L3	ENSG00000198758	0.214709592955647	[16]	[21,15]	2	hSpCas9	negative selection	3285720
109753174	109753197		+	24336571	A375	viability after 14 days	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.5566310121332775	[25]	[32,39]	7	hSpCas9	negative selection	3285721
109751325	109751348	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.018189718475271035	[144,164]	[0,0]	0	hSpCas9	positive selection	3348213
109751326	109751349	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	0.008220506804968365	[170,132]	[0,0]	0	hSpCas9	positive selection	3348214
109750736	109750759	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.021533161549641133	[123,186]	[0,0]	0	hSpCas9	positive selection	3348215
109750749	109750772	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-1.1002257931722488	[327,327]	[0,0]	-7	hSpCas9	positive selection	3367423
109753174	109753197	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.038157690983673484	[148,148]	[0,0]	0	hSpCas9	positive selection	3367424
109753184	109753207	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	-0.600654783681737	[231,231]	[0,0]	-4	hSpCas9	positive selection	3367425
109759813	109759836	1	-	26780180	HT29	viability (Avana library 4 designs)	ACTTGATGACATGCAAGCAGGGG	EPS8L3	ENSG00000198758	1.2067959978721	[]	[]	5	hSpCas9	negative selection	3422986
109758575	109758598	1	+	26780180	HT29	viability (Avana library 4 designs)	GATAGCGTGCCTGCTCCATAGGG	EPS8L3	ENSG00000198758	1.08603012175195	[]	[]	4	hSpCas9	negative selection	3422987
109761552	109761575	1	-	26780180	HT29	viability (Avana library 4 designs)	TCTGTGCCCTTGTAGTGCACCGG	EPS8L3	ENSG00000198758	1.63965896215424	[]	[]	6	hSpCas9	negative selection	3422988
109758349	109758372	1	-	26780180	HT29	viability (Avana library 4 designs)	TTACTCTGCCTCCTCCAAGGCGG	EPS8L3	ENSG00000198758	1.24278604511041	[]	[]	5	hSpCas9	negative selection	3422989
109758349	109758372	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTCTGCCTCCTCCAAGGCGG	EPS8L3	ENSG00000198758	-0.127332222747129	[]	[]	0	hSpCas9	negative selection	3503917
109758575	109758598	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATAGCGTGCCTGCTCCATAGGG	EPS8L3	ENSG00000198758	5.76280908470471	[]	[]	9	hSpCas9	negative selection	3503918
109759813	109759836	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTGATGACATGCAAGCAGGGG	EPS8L3	ENSG00000198758	-6.61966978534183	[]	[]	-6	hSpCas9	negative selection	3503919
109761552	109761575	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGTGCCCTTGTAGTGCACCGG	EPS8L3	ENSG00000198758	0.334656110512612	[]	[]	0	hSpCas9	negative selection	3503920
109758025	109758048	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAATGTCCCTTAGGACATGG	EPS8L3	ENSG00000198758	2.55020555701232	[]	[]	4	hSpCas9	negative selection	3503921
109758333	109758356	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGGCGGTCCTCTTCCCCCGAGG	EPS8L3	ENSG00000198758	6.64553360707379	[]	[]	9	hSpCas9	negative selection	3503922
109758349	109758372	1	-	26780180	A375	viability (Avana lentiGuide)	TTACTCTGCCTCCTCCAAGGCGG	EPS8L3	ENSG00000198758	10.9872515404811	[]	[]	7	hSpCas9	negative selection	3612576
109758575	109758598	1	+	26780180	A375	viability (Avana lentiGuide)	GATAGCGTGCCTGCTCCATAGGG	EPS8L3	ENSG00000198758	0.663975346466201	[]	[]	0	hSpCas9	negative selection	3612577
109759813	109759836	1	-	26780180	A375	viability (Avana lentiGuide)	ACTTGATGACATGCAAGCAGGGG	EPS8L3	ENSG00000198758	7.44604786006536	[]	[]	6	hSpCas9	negative selection	3612578
109761552	109761575	1	-	26780180	A375	viability (Avana lentiGuide)	TCTGTGCCCTTGTAGTGCACCGG	EPS8L3	ENSG00000198758	4.91371144737017	[]	[]	4	hSpCas9	negative selection	3612579
109758025	109758048	1	+	26780180	A375	viability (Avana lentiGuide)	GCTCAATGTCCCTTAGGACATGG	EPS8L3	ENSG00000198758	0.336932367576922	[]	[]	0	hSpCas9	negative selection	3612580
109758333	109758356	1	-	26780180	A375	viability (Avana lentiGuide)	AAGGCGGTCCTCTTCCCCCGAGG	EPS8L3	ENSG00000198758	2.14521850332648	[]	[]	2	hSpCas9	negative selection	3612581
109758349	109758372	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTCTGCCTCCTCCAAGGCGG	EPS8L3	ENSG00000198758	-0.23008913482112953	[5]	[4,4]	-4	hSpCas9	positive selection	3721235
109758575	109758598	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATAGCGTGCCTGCTCCATAGGG	EPS8L3	ENSG00000198758	0.2067773400874029	[5]	[6,5]	6	hSpCas9	positive selection	3721236
109759813	109759836	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTGATGACATGCAAGCAGGGG	EPS8L3	ENSG00000198758	-0.7399070452585828	[4]	[1,2]	-8	hSpCas9	positive selection	3721237
109761552	109761575	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGTGCCCTTGTAGTGCACCGG	EPS8L3	ENSG00000198758	-0.03652554534222385	[5]	[5,5]	0	hSpCas9	positive selection	3721238
109758025	109758048	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAATGTCCCTTAGGACATGG	EPS8L3	ENSG00000198758	0.16941613337243677	[5]	[6,6]	4	hSpCas9	positive selection	3721239
109758333	109758356	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGGCGGTCCTCTTCCCCCGAGG	EPS8L3	ENSG00000198758	0.22634774932190446	[4]	[4,5]	6	hSpCas9	positive selection	3721240
109758349	109758372	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTCTGCCTCCTCCAAGGCGG	EPS8L3	ENSG00000198758	-0.3283972822564925	[5]	[4,2]	-4	hSpCas9	positive selection	3829842
109758575	109758598	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATAGCGTGCCTGCTCCATAGGG	EPS8L3	ENSG00000198758	-0.028822862485477142	[5]	[4,4]	0	hSpCas9	positive selection	3829843
109759813	109759836	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTGATGACATGCAAGCAGGGG	EPS8L3	ENSG00000198758	-0.8864341644677546	[4]	[1,1]	-8	hSpCas9	positive selection	3829844
109761552	109761575	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGTGCCCTTGTAGTGCACCGG	EPS8L3	ENSG00000198758	0.0023932619682136003	[5]	[4,5]	0	hSpCas9	positive selection	3829845
109758025	109758048	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAATGTCCCTTAGGACATGG	EPS8L3	ENSG00000198758	0.14472048079221705	[6]	[6,5]	3	hSpCas9	positive selection	3829846
109758333	109758356	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGGCGGTCCTCTTCCCCCGAGG	EPS8L3	ENSG00000198758	0.28281271937326735	[5]	[5,5]	7	hSpCas9	positive selection	3829847
109751325	109751348	1	-	26780180	A375	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.826452836104153	[]	[]	3	hSpCas9	negative selection	3937197
109750736	109750759	1	-	26780180	A375	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	2.01365099356641	[]	[]	9	hSpCas9	negative selection	3937198
109751326	109751349	1	+	26780180	A375	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	1.75078254331721	[]	[]	9	hSpCas9	negative selection	3937199
109753184	109753207	1	-	26780180	A375	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.786589109846225	[]	[]	3	hSpCas9	negative selection	3937200
109750749	109750772	1	+	26780180	A375	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.152063987635471	[]	[]	0	hSpCas9	negative selection	3937201
109753174	109753197	1	+	26780180	A375	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.405170422434164	[]	[]	1	hSpCas9	negative selection	3937202
109751325	109751348	1	-	26780180	HT29	viability (GeCKOv2 library)	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.460686813646857	[]	[]	1	hSpCas9	negative selection	4045163
109750736	109750759	1	-	26780180	HT29	viability (GeCKOv2 library)	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	2.09583377504303	[]	[]	9	hSpCas9	negative selection	4045164
109751326	109751349	1	+	26780180	HT29	viability (GeCKOv2 library)	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	1.28047408445524	[]	[]	6	hSpCas9	negative selection	4045165
109753184	109753207	1	-	26780180	HT29	viability (GeCKOv2 library)	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.632141250060342	[]	[]	2	hSpCas9	negative selection	4045166
109750749	109750772	1	+	26780180	HT29	viability (GeCKOv2 library)	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.247814006804923	[]	[]	0	hSpCas9	negative selection	4045167
109753174	109753197	1	+	26780180	HT29	viability (GeCKOv2 library)	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.191823055539135	[]	[]	0	hSpCas9	negative selection	4045168
109751325	109751348	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.34064493721043043	[5]	[5,3]	7	hSpCas9	positive selection	4135064
109753184	109753207	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	-0.009297030514179239	[5]	[3,3]	0	hSpCas9	positive selection	4135065
109753106	109753129	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCCCCTTACTTGGCTGGAGGG	EPS8L3	ENSG00000198758	-0.012888467827927491	[4]	[2,2]	0	hSpCas9	positive selection	4135066
109753174	109753197	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.156296796896227	[4]	[3,3]	4	hSpCas9	positive selection	4135067
109751325	109751348	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	1.2442718023194015	[3]	[4,4,3,4]	8	hSpCas9	positive selection	4199086
109753184	109753207	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.8424212236117479	[5]	[2,5,4,3]	5	hSpCas9	positive selection	4199087
109753106	109753129	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCCCCTTACTTGGCTGGAGGG	EPS8L3	ENSG00000198758	0.7434260804873426	[3]	[4,4,4,0]	5	hSpCas9	positive selection	4199088
109753174	109753197	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.4827644390986013	[4]	[4,3,6,0]	3	hSpCas9	positive selection	4199089
109751325	109751348	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.06645444060848979	[3]	[3,1]	1	hSpCas9	positive selection	4269072
109751326	109751349	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	0.16230898076874378	[3]	[3,2]	3	hSpCas9	positive selection	4269073
109750736	109750759	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.004454876667641577	[3]	[2,2]	0	hSpCas9	positive selection	4269074
109750749	109750772	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.0057833556724719015	[3]	[3,2]	0	hSpCas9	positive selection	4333337
109753174	109753197	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	-0.028308781317113785	[2]	[3,1]	0	hSpCas9	positive selection	4333338
109753184	109753207	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.5536799993615569	[3]	[3,4]	9	hSpCas9	positive selection	4333339
109758374	109758396	1	+	27760321	OCIAML3	viability	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	0.05619963027075614	[925,861]	[777,660]	0	hSpCas9	negative selection	4398123
109758564	109758586	1	-	27760321	OCIAML3	viability	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.6873261227544313	[883,775]	[941,1174]	7	hSpCas9	negative selection	4398124
109758590	109758612	1	-	27760321	OCIAML3	viability	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.7577603131516668	[364,323]	[489,408]	8	hSpCas9	negative selection	4398125
109758652	109758674	1	-	27760321	OCIAML3	viability	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.41896536354171643	[364,290]	[369,302]	5	hSpCas9	negative selection	4398126
109759752	109759774	1	-	27760321	OCIAML3	viability	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.15906926394730414	[491,433]	[347,475]	1	hSpCas9	negative selection	4398127
109758374	109758396	1	+	27760321	OCIAML2	viability	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	0.30672121621664217	[925,861]	[833,974]	4	hSpCas9	negative selection	4481586
109758564	109758586	1	-	27760321	OCIAML2	viability	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.2545979914507074	[883,775]	[722,899]	3	hSpCas9	negative selection	4481587
109758590	109758612	1	-	27760321	OCIAML2	viability	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.6575827239591692	[364,323]	[368,530]	8	hSpCas9	negative selection	4481588
109758652	109758674	1	-	27760321	OCIAML2	viability	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.08834777512918707	[364,290]	[282,276]	1	hSpCas9	negative selection	4481589
109759752	109759774	1	-	27760321	OCIAML2	viability	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.08111224606850977	[491,433]	[292,432]	-1	hSpCas9	negative selection	4481590
109758374	109758396	1	+	27760321	MV411	viability	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	0.3462867449705169	[925,861]	[816,649]	2	hSpCas9	negative selection	4565049
109758564	109758586	1	-	27760321	MV411	viability	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	1.4113988712260142	[883,775]	[1339,1624]	8	hSpCas9	negative selection	4565050
109758590	109758612	1	-	27760321	MV411	viability	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	2.0155159138733056	[364,323]	[1284,365]	9	hSpCas9	negative selection	4565051
109758652	109758674	1	-	27760321	MV411	viability	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.32819169773722723	[364,290]	[164,427]	2	hSpCas9	negative selection	4565052
109759752	109759774	1	-	27760321	MV411	viability	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.8019801510172491	[491,433]	[74,324]	-5	hSpCas9	negative selection	4565053
109758374	109758396	1	+	27760321	HL60	viability	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	-0.04515615397514239	[925,861]	[824,583]	0	hSpCas9	negative selection	4648512
109758564	109758586	1	-	27760321	HL60	viability	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.26596901339391354	[883,775]	[799,827]	3	hSpCas9	negative selection	4648513
109758590	109758612	1	-	27760321	HL60	viability	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.5115157919493768	[364,323]	[301,504]	6	hSpCas9	negative selection	4648514
109758652	109758674	1	-	27760321	HL60	viability	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.0781458989165546	[364,290]	[302,257]	1	hSpCas9	negative selection	4648515
109759752	109759774	1	-	27760321	HL60	viability	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.18938028379823285	[491,433]	[349,310]	-2	hSpCas9	negative selection	4648516
109758374	109758396	1	+	27760321	HT1080	viability	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	0.7760239696839863	[861,672]	[461,590]	4	hSpCas9	negative selection	4731975
109758564	109758586	1	-	27760321	HT1080	viability	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.9764062110535666	[775,605]	[670,399]	5	hSpCas9	negative selection	4731976
109758590	109758612	1	-	27760321	HT1080	viability	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	1.7412876816104412	[323,252]	[315,458]	8	hSpCas9	negative selection	4731977
109758652	109758674	1	-	27760321	HT1080	viability	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.3522456363440323	[290,226]	[114,149]	1	hSpCas9	negative selection	4731978
109759752	109759774	1	-	27760321	HT1080	viability	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.05940510926998817	[433,338]	[184,106]	0	hSpCas9	negative selection	4731979
109758374	109758396	1	+	27760321	HT29	viability after 7 days	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	-0.03671706695723187	[861,672]	[1421,908,629]	0	hSpCas9	negative selection	4815438
109758564	109758586	1	-	27760321	HT29	viability after 7 days	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.4447396291619289	[775,605]	[1387,1260,1008]	6	hSpCas9	negative selection	4815439
109758590	109758612	1	-	27760321	HT29	viability after 7 days	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.38182721291230415	[323,252]	[678,276,519]	6	hSpCas9	negative selection	4815440
109758652	109758674	1	-	27760321	HT29	viability after 7 days	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.65886303697597	[290,226]	[430,639,492]	8	hSpCas9	negative selection	4815441
109759752	109759774	1	-	27760321	HT29	viability after 7 days	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.08397974155614231	[433,338]	[518,487,407]	-1	hSpCas9	negative selection	4815442
109758374	109758396	1	+	27760321	HT29	viability after 25 days	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	0.2483889903273977	[861,672]	[952,1141,1033]	2	hSpCas9	negative selection	4898901
109758564	109758586	1	-	27760321	HT29	viability after 25 days	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.3495949155636594	[775,605]	[1121,915,967]	4	hSpCas9	negative selection	4898902
109758590	109758612	1	-	27760321	HT29	viability after 25 days	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.6026911750886681	[323,252]	[606,305,590]	6	hSpCas9	negative selection	4898903
109758652	109758674	1	-	27760321	HT29	viability after 25 days	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.535485316067832	[290,226]	[423,361,508]	6	hSpCas9	negative selection	4898904
109759752	109759774	1	-	27760321	HT29	viability after 25 days	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.07184378223362227	[433,338]	[400,505,491]	0	hSpCas9	negative selection	4898905
109758374	109758396	1	+	27760321	HT29	viability after 22 days	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	-0.11183916810190297	[861,672]	[627,1070,768]	-1	hSpCas9	negative selection	4982364
109758564	109758586	1	-	27760321	HT29	viability after 22 days	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.38390636318011906	[775,605]	[1216,1224,676]	4	hSpCas9	negative selection	4982365
109758590	109758612	1	-	27760321	HT29	viability after 22 days	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.39676195982800355	[323,252]	[501,333,479]	4	hSpCas9	negative selection	4982366
109758652	109758674	1	-	27760321	HT29	viability after 22 days	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.28316509961916303	[290,226]	[448,246,394]	3	hSpCas9	negative selection	4982367
109759752	109759774	1	-	27760321	HT29	viability after 22 days	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.21982144210703153	[433,338]	[375,312,462]	-2	hSpCas9	negative selection	4982368
109758374	109758396	1	+	27760321	HT29	viability after 19 days	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	-0.3980882874523467	[861,672]	[780,885,354]	-4	hSpCas9	negative selection	5065827
109758564	109758586	1	-	27760321	HT29	viability after 19 days	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.27122313461073444	[775,605]	[1263,912,724]	2	hSpCas9	negative selection	5065828
109758590	109758612	1	-	27760321	HT29	viability after 19 days	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.40661908934207486	[323,252]	[562,350,411]	4	hSpCas9	negative selection	5065829
109758652	109758674	1	-	27760321	HT29	viability after 19 days	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.07831504662789562	[290,226]	[330,352,257]	0	hSpCas9	negative selection	5065830
109759752	109759774	1	-	27760321	HT29	viability after 19 days	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.5493878710816446	[433,338]	[307,226,368]	-5	hSpCas9	negative selection	5065831
109758374	109758396	1	+	27760321	HT29	viability after 16 days	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	0.04119313288215665	[861,672]	[637,1012,972]	0	hSpCas9	negative selection	5149290
109758564	109758586	1	-	27760321	HT29	viability after 16 days	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.25960284354099994	[775,605]	[1145,898,752]	3	hSpCas9	negative selection	5149291
109758590	109758612	1	-	27760321	HT29	viability after 16 days	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.388524789246919	[323,252]	[221,675,343]	4	hSpCas9	negative selection	5149292
109758652	109758674	1	-	27760321	HT29	viability after 16 days	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.529252438907107	[290,226]	[613,301,359]	6	hSpCas9	negative selection	5149293
109759752	109759774	1	-	27760321	HT29	viability after 16 days	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.17156320328620422	[433,338]	[450,235,474]	-2	hSpCas9	negative selection	5149294
109758374	109758396	1	+	27760321	HT29	viability after 13 days	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	0.03713400903736219	[861,672]	[874,904,957]	0	hSpCas9	negative selection	5232753
109758564	109758586	1	-	27760321	HT29	viability after 13 days	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.3316205403167559	[775,605]	[1168,1155,718]	4	hSpCas9	negative selection	5232754
109758590	109758612	1	-	27760321	HT29	viability after 13 days	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.390601289955194	[323,252]	[322,511,478]	5	hSpCas9	negative selection	5232755
109758652	109758674	1	-	27760321	HT29	viability after 13 days	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.16528692595718408	[290,226]	[378,283,346]	2	hSpCas9	negative selection	5232756
109759752	109759774	1	-	27760321	HT29	viability after 13 days	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.027934078367517615	[433,338]	[303,494,565]	0	hSpCas9	negative selection	5232757
109758374	109758396	1	+	27760321	HT29	viability after 10 days	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	-0.13813242771961443	[861,672]	[822,1067,729]	-2	hSpCas9	negative selection	5316216
109758564	109758586	1	-	27760321	HT29	viability after 10 days	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.23541503359833615	[775,605]	[939,829,1265]	3	hSpCas9	negative selection	5316217
109758590	109758612	1	-	27760321	HT29	viability after 10 days	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	0.22570453335750526	[323,252]	[521,283,452]	3	hSpCas9	negative selection	5316218
109758652	109758674	1	-	27760321	HT29	viability after 10 days	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	0.17483732433847482	[290,226]	[437,351,305]	2	hSpCas9	negative selection	5316219
109759752	109759774	1	-	27760321	HT29	viability after 10 days	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.43272436452792207	[433,338]	[372,439,263]	-5	hSpCas9	negative selection	5316220
109758374	109758396	1	+	27760321	MOLM13	viability	GCACTTGGTTCTCGGGCACTGG	EPS8L3	ENSG00000198758	1.209413895633673	[925,861]	[1458,917]	8	hSpCas9	negative selection	5399679
109758564	109758586	1	-	27760321	MOLM13	viability	GGCACGCTATCTGGAGCCGGGG	EPS8L3	ENSG00000198758	0.2615898795856063	[883,775]	[489,619]	1	hSpCas9	negative selection	5399680
109758590	109758612	1	-	27760321	MOLM13	viability	ATGGAAAGGCCGCTCCCTATGG	EPS8L3	ENSG00000198758	1.0878664464137102	[364,323]	[479,354]	7	hSpCas9	negative selection	5399681
109758652	109758674	1	-	27760321	MOLM13	viability	TCCTCAGCAGACCTCGACTTGG	EPS8L3	ENSG00000198758	-0.3777130412431829	[364,290]	[79,193]	-2	hSpCas9	negative selection	5399682
109759752	109759774	1	-	27760321	MOLM13	viability	CTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.0484967383784078	[491,433]	[233,299]	0	hSpCas9	negative selection	5399683
109763838	109763861	1	+	27661255	K562	viability	GCCGGGTGCCTGGTCCCCCCAGG	EPS8L3	ENSG00000198758	-0.19579875568295407	[701,857]	[588,501]	-6	dCas9-KRAB	negative selection	5477652
109751325	109751348	1	-	27260156	BXPC3	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.004462074843700203	[627]	[630,670,633,700]	0	hSpCas9	negative selection	5541532
109751326	109751349	1	+	27260156	BXPC3	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.4808570620849017	[804]	[516,526,623,775]	-8	hSpCas9	negative selection	5541533
109750736	109750759	1	-	27260156	BXPC3	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.3389748455820618	[723]	[647,499,618,626]	-6	hSpCas9	negative selection	5541534
109750749	109750772	1	+	27260156	BXPC3	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.07084615046010512	[893]	[799,834,997,941]	-2	hSpCas9	negative selection	5605797
109753174	109753197	1	+	27260156	BXPC3	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.11294624953695577	[439]	[523,440,503,520]	2	hSpCas9	negative selection	5605798
109753184	109753207	1	-	27260156	BXPC3	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.11230643051157196	[651]	[717,584,790,877]	2	hSpCas9	negative selection	5605799
109751325	109751348	1	-	27260156	A673	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.113917357613808	[627]	[956,816,759,740]	2	hSpCas9	negative selection	5662783
109751326	109751349	1	+	27260156	A673	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.1652250566829766	[804]	[820,844,905,869]	-4	hSpCas9	negative selection	5662784
109750736	109750759	1	-	27260156	A673	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.09070624163114571	[723]	[702,672,931,952]	-2	hSpCas9	negative selection	5662785
109750749	109750772	1	+	27260156	A673	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.16740905268472928	[893]	[1052,850,905,1029]	-4	hSpCas9	negative selection	5727048
109753174	109753197	1	+	27260156	A673	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.1587800471795407	[439]	[628,448,568,726]	4	hSpCas9	negative selection	5727049
109753184	109753207	1	-	27260156	A673	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.18033862697875347	[651]	[937,771,839,1012]	4	hSpCas9	negative selection	5727050
109751325	109751348	1	-	27260156	A375	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.12282806456725853	[627]	[774,838,569,546]	-2	hSpCas9	negative selection	5784034
109751326	109751349	1	+	27260156	A375	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.6442863636714968	[804]	[686,744,524,481]	-7	hSpCas9	negative selection	5784035
109750736	109750759	1	-	27260156	A375	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.1530801671817521	[723]	[673,945,635,802]	-2	hSpCas9	negative selection	5784036
109750749	109750772	1	+	27260156	A375	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.3488105345121457	[893]	[847,941,732,775]	-5	hSpCas9	negative selection	5848299
109753174	109753197	1	+	27260156	A375	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.4420145966294574	[439]	[769,691,651,677]	6	hSpCas9	negative selection	5848300
109753184	109753207	1	-	27260156	A375	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.4196183811948053	[651]	[945,1002,1231,900]	6	hSpCas9	negative selection	5848301
109751325	109751348	1	-	27260156	COLO741	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.21568094956475875	[627]	[996,985,823]	4	hSpCas9	negative selection	5905285
109751326	109751349	1	+	27260156	COLO741	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.5297809268041099	[804]	[724,855,566]	-8	hSpCas9	negative selection	5905286
109750736	109750759	1	-	27260156	COLO741	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.07619672853271087	[723]	[1024,786,833]	-2	hSpCas9	negative selection	5905287
109750749	109750772	1	+	27260156	COLO741	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.04524701110973173	[893]	[1001,1508,1019]	1	hSpCas9	negative selection	5969550
109753174	109753197	1	+	27260156	COLO741	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.19180871562421403	[439]	[820,716,418]	4	hSpCas9	negative selection	5969551
109753184	109753207	1	-	27260156	COLO741	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.20864344534358958	[651]	[1196,866,849]	4	hSpCas9	negative selection	5969552
109751325	109751348	1	-	27260156	CAL120	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.1798257177814429	[627]	[1195,618,886]	2	hSpCas9	negative selection	6026536
109751326	109751349	1	+	27260156	CAL120	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-1.0156652050891706	[804]	[684,351,477]	-8	hSpCas9	negative selection	6026537
109750736	109750759	1	-	27260156	CAL120	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.34093756606627246	[723]	[832,665,653]	-5	hSpCas9	negative selection	6026538
109750749	109750772	1	+	27260156	CAL120	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.02875395680960191	[893]	[1079,1235,955]	0	hSpCas9	negative selection	6090801
109753174	109753197	1	+	27260156	CAL120	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.3825678490891156	[439]	[798,925,433]	6	hSpCas9	negative selection	6090802
109753184	109753207	1	-	27260156	CAL120	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.4365837837302897	[651]	[1015,1424,844]	6	hSpCas9	negative selection	6090803
109751325	109751348	1	-	27260156	CADOES1	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.0735147736221401	[627]	[647,566,736,501]	1	hSpCas9	negative selection	6147787
109751326	109751349	1	+	27260156	CADOES1	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.3739682902813006	[804]	[537,472,665,635]	-6	hSpCas9	negative selection	6147788
109750736	109750759	1	-	27260156	CADOES1	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.05168531515252406	[723]	[698,604,928,552]	0	hSpCas9	negative selection	6147789
109750749	109750772	1	+	27260156	CADOES1	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.16456336586254527	[893]	[1034,728,1082,877]	3	hSpCas9	negative selection	6212052
109753174	109753197	1	+	27260156	CADOES1	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	-0.08328402937497383	[439]	[310,393,460,378]	-1	hSpCas9	negative selection	6212053
109753184	109753207	1	-	27260156	CADOES1	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.5693458822292177	[651]	[893,834,793,1082]	8	hSpCas9	negative selection	6212054
109751325	109751348	1	-	27260156	EWS502	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.19413804208645108	[627]	[614,961,659,815]	3	hSpCas9	negative selection	6269038
109751326	109751349	1	+	27260156	EWS502	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.6425918586680028	[804]	[450,457,591,708]	-8	hSpCas9	negative selection	6269039
109750736	109750759	1	-	27260156	EWS502	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.24179131978659724	[723]	[624,679,558,733]	-4	hSpCas9	negative selection	6269040
109750749	109750772	1	+	27260156	EWS502	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.04363114185200856	[893]	[768,777,1037,1377]	0	hSpCas9	negative selection	6333303
109753174	109753197	1	+	27260156	EWS502	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.3371492157440685	[439]	[478,684,517,685]	6	hSpCas9	negative selection	6333304
109753184	109753207	1	-	27260156	EWS502	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.1614068822412652	[651]	[777,568,973,775]	3	hSpCas9	negative selection	6333305
109751325	109751348	1	-	27260156	EW8	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.026291754034369452	[627]	[595,516,328,669]	0	hSpCas9	negative selection	6390289
109751326	109751349	1	+	27260156	EW8	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.299700764751829	[804]	[472,500,504,636]	-5	hSpCas9	negative selection	6390290
109750736	109750759	1	-	27260156	EW8	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.23867703508932037	[723]	[480,407,587,492]	-4	hSpCas9	negative selection	6390291
109750749	109750772	1	+	27260156	EW8	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.3639149348427597	[893]	[641,643,525,453]	-6	hSpCas9	negative selection	6454554
109753174	109753197	1	+	27260156	EW8	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	-0.1151887733542931	[439]	[380,333,249,369]	-2	hSpCas9	negative selection	6454555
109753184	109753207	1	-	27260156	EW8	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.2459276808312011	[651]	[812,493,623,593]	4	hSpCas9	negative selection	6454556
109751325	109751348	1	-	27260156	CORL105	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.0839324328715087	[627]	[627,749,862,556]	-1	hSpCas9	negative selection	6511540
109751326	109751349	1	+	27260156	CORL105	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.7431336424831699	[804]	[530,582,791,380]	-8	hSpCas9	negative selection	6511541
109750736	109750759	1	-	27260156	CORL105	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.27439110387174276	[723]	[993,565,661,587]	-5	hSpCas9	negative selection	6511542
109750749	109750772	1	+	27260156	CORL105	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.3017324489478803	[893]	[733,871,978,826]	-5	hSpCas9	negative selection	6575805
109753174	109753197	1	+	27260156	CORL105	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.1718392920468227	[439]	[581,502,785,483]	3	hSpCas9	negative selection	6575806
109753184	109753207	1	-	27260156	CORL105	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.1790239371241158	[651]	[881,777,1068,761]	3	hSpCas9	negative selection	6575807
109751325	109751348	1	-	27260156	HS294T	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.17792501139837624	[627]	[159,269,187,248]	-3	hSpCas9	negative selection	6632791
109751326	109751349	1	+	27260156	HS294T	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.08182631263746232	[804]	[130,330,428,299]	-1	hSpCas9	negative selection	6632792
109750736	109750759	1	-	27260156	HS294T	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.46380699440754136	[723]	[340,247,532,438]	6	hSpCas9	negative selection	6632793
109750749	109750772	1	+	27260156	HS294T	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.0852310036681253	[893]	[293,430,290,471]	1	hSpCas9	negative selection	6697056
109753174	109753197	1	+	27260156	HS294T	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.2846622546564383	[439]	[210,187,139,305]	4	hSpCas9	negative selection	6697057
109753184	109753207	1	-	27260156	HS294T	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.5700266529693729	[651]	[200,323,486,527]	7	hSpCas9	negative selection	6697058
109751325	109751348	1	-	27260156	HCC44	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.3141312336402258	[627]	[1172,682,1011,738]	5	hSpCas9	negative selection	6754042
109751326	109751349	1	+	27260156	HCC44	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.9013474317412697	[804]	[475,468,710,334]	-8	hSpCas9	negative selection	6754043
109750736	109750759	1	-	27260156	HCC44	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.18308933670768174	[723]	[818,661,769,655]	-3	hSpCas9	negative selection	6754044
109750749	109750772	1	+	27260156	HCC44	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.028408302310272027	[893]	[802,845,1594,976]	0	hSpCas9	negative selection	6818307
109753174	109753197	1	+	27260156	HCC44	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.44643310913957523	[439]	[743,648,737,598]	7	hSpCas9	negative selection	6818308
109753184	109753207	1	-	27260156	HCC44	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.41000483049613423	[651]	[1248,738,1178,841]	6	hSpCas9	negative selection	6818309
109751325	109751348	1	-	27260156	G402	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.06533066947204946	[627]	[1433,511,1113,245]	0	hSpCas9	negative selection	6875293
109751326	109751349	1	+	27260156	G402	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.5462988285066492	[804]	[1261,616,561,344]	-6	hSpCas9	negative selection	6875294
109750736	109750759	1	-	27260156	G402	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.6056054695976614	[723]	[929,407,515,509]	-6	hSpCas9	negative selection	6875295
109750749	109750772	1	+	27260156	G402	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.35422468832639986	[893]	[2565,1112,880,1175]	4	hSpCas9	negative selection	6939558
109753174	109753197	1	+	27260156	G402	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.11433117525025523	[439]	[813,544,499,498]	1	hSpCas9	negative selection	6939559
109753184	109753207	1	-	27260156	G402	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.32713064535172387	[651]	[1274,1273,891,621]	4	hSpCas9	negative selection	6939560
109751325	109751348	1	-	27260156	L33	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.19392402929454694	[627]	[598,381,396,712]	4	hSpCas9	negative selection	6996544
109751326	109751349	1	+	27260156	L33	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.23161028570077902	[804]	[811,288,431,535]	-5	hSpCas9	negative selection	6996545
109750736	109750759	1	-	27260156	L33	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.028782476877433627	[723]	[853,266,519,619]	0	hSpCas9	negative selection	6996546
109750749	109750772	1	+	27260156	L33	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.03512686359695272	[893]	[852,370,517,1080]	0	hSpCas9	negative selection	7060809
109753174	109753197	1	+	27260156	L33	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	-0.2359547890008728	[439]	[399,202,188,297]	-5	hSpCas9	negative selection	7060810
109753184	109753207	1	-	27260156	L33	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	-0.07328647019279177	[651]	[768,278,304,539]	-2	hSpCas9	negative selection	7060811
109751325	109751348	1	-	27260156	K562	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.11232263184241886	[627]	[580,583,463,447]	-1	hSpCas9	negative selection	7117795
109751326	109751349	1	+	27260156	K562	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.9629836128193346	[804]	[474,292,274,419]	-8	hSpCas9	negative selection	7117796
109750736	109750759	1	-	27260156	K562	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.470136992269076	[723]	[466,303,391,658]	-5	hSpCas9	negative selection	7117797
109750749	109750772	1	+	27260156	K562	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.048477708526339036	[893]	[855,903,752,587]	0	hSpCas9	negative selection	7182060
109753174	109753197	1	+	27260156	K562	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.16108299893242567	[439]	[329,291,648,454]	2	hSpCas9	negative selection	7182061
109753184	109753207	1	-	27260156	K562	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.5548568367740445	[651]	[1051,795,730,832]	7	hSpCas9	negative selection	7182062
109751325	109751348	1	-	27260156	HT29	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.06038668636309491	[627]	[564,807,750,785]	-1	hSpCas9	negative selection	7239046
109751326	109751349	1	+	27260156	HT29	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.46403088713442486	[804]	[752,785,679,632]	-7	hSpCas9	negative selection	7239047
109750736	109750759	1	-	27260156	HT29	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.05850904298706394	[723]	[937,786,846,808]	-1	hSpCas9	negative selection	7239048
109750749	109750772	1	+	27260156	HT29	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.20337285030530505	[893]	[1657,1273,996,1116]	4	hSpCas9	negative selection	7303311
109753174	109753197	1	+	27260156	HT29	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.15222218553730202	[439]	[661,555,480,666]	3	hSpCas9	negative selection	7303312
109753184	109753207	1	-	27260156	HT29	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.0208313324044051	[651]	[786,785,958,689]	0	hSpCas9	negative selection	7303313
109751325	109751348	1	-	27260156	MHHES1	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.16472596073885665	[627]	[743,955,792,693]	3	hSpCas9	negative selection	7360297
109751326	109751349	1	+	27260156	MHHES1	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.5032073817465752	[804]	[674,905,614,428]	-7	hSpCas9	negative selection	7360298
109750736	109750759	1	-	27260156	MHHES1	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.2080281016382195	[723]	[670,1213,967,897]	4	hSpCas9	negative selection	7360299
109750749	109750772	1	+	27260156	MHHES1	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.014154124135025592	[893]	[1117,983,835,1030]	0	hSpCas9	negative selection	7424562
109753174	109753197	1	+	27260156	MHHES1	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.20553250915561438	[439]	[743,339,750,461]	4	hSpCas9	negative selection	7424563
109753184	109753207	1	-	27260156	MHHES1	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.4730967862443818	[651]	[1108,1209,1108,725]	8	hSpCas9	negative selection	7424564
109751325	109751348	1	-	27260156	MEWO	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.05981097304671229	[627]	[650,519,673]	1	hSpCas9	negative selection	7481548
109751326	109751349	1	+	27260156	MEWO	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.05470426703362097	[804]	[806,728,654]	-1	hSpCas9	negative selection	7481549
109750736	109750759	1	-	27260156	MEWO	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.015188075872497042	[723]	[844,578,660]	0	hSpCas9	negative selection	7481550
109750749	109750772	1	+	27260156	MEWO	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.08551025536034917	[893]	[978,696,725]	-2	hSpCas9	negative selection	7545813
109753174	109753197	1	+	27260156	MEWO	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.12280168378029348	[439]	[510,391,453]	2	hSpCas9	negative selection	7545814
109753184	109753207	1	-	27260156	MEWO	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.3294954248101176	[651]	[899,596,828]	7	hSpCas9	negative selection	7545815
109751325	109751348	1	-	27260156	LNCAPCLONEFGC	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.16843182107630258	[627]	[477,505,539,505]	-3	hSpCas9	negative selection	7602799
109751326	109751349	1	+	27260156	LNCAPCLONEFGC	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.8075666956930647	[804]	[425,309,644,325]	-8	hSpCas9	negative selection	7602800
109750736	109750759	1	-	27260156	LNCAPCLONEFGC	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.1115935395113663	[723]	[600,547,662,627]	-2	hSpCas9	negative selection	7602801
109750749	109750772	1	+	27260156	LNCAPCLONEFGC	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.03387843318325556	[893]	[866,631,1030,827]	0	hSpCas9	negative selection	7667064
109753174	109753197	1	+	27260156	LNCAPCLONEFGC	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.36215250390340437	[439]	[368,483,784,455]	6	hSpCas9	negative selection	7667065
109753184	109753207	1	-	27260156	LNCAPCLONEFGC	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.4577786149369677	[651]	[764,838,782,851]	7	hSpCas9	negative selection	7667066
109751325	109751348	1	-	27260156	PANC0327	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.022986073007127683	[627]	[678,417,370,826]	0	hSpCas9	negative selection	7724050
109751326	109751349	1	+	27260156	PANC0327	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.3108226937430702	[804]	[725,501,702,396]	-4	hSpCas9	negative selection	7724051
109750736	109750759	1	-	27260156	PANC0327	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.06966213301369895	[723]	[714,658,357,720]	-1	hSpCas9	negative selection	7724052
109750749	109750772	1	+	27260156	PANC0327	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.15033146444926226	[893]	[1150,790,854,761]	2	hSpCas9	negative selection	7788315
109753174	109753197	1	+	27260156	PANC0327	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	-0.1692245903974322	[439]	[403,275,293,429]	-3	hSpCas9	negative selection	7788316
109753184	109753207	1	-	27260156	PANC0327	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.5428260360442052	[651]	[1074,635,1035,673]	7	hSpCas9	negative selection	7788317
109751325	109751348	1	-	27260156	NCIH2009	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.10208461476222425	[627]	[1076,1072,697]	1	hSpCas9	negative selection	7845301
109751326	109751349	1	+	27260156	NCIH2009	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.31753612263202724	[804]	[1537,715,580]	-4	hSpCas9	negative selection	7845302
109750736	109750759	1	-	27260156	NCIH2009	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.11253587834794854	[723]	[1153,1197,936]	1	hSpCas9	negative selection	7845303
109750749	109750772	1	+	27260156	NCIH2009	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.1141988459891673	[893]	[1542,1313,1234]	1	hSpCas9	negative selection	7909566
109753174	109753197	1	+	27260156	NCIH2009	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.16045842203761454	[439]	[776,676,623]	2	hSpCas9	negative selection	7909567
109753184	109753207	1	-	27260156	NCIH2009	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.21716040858616759	[651]	[1037,1104,1026]	3	hSpCas9	negative selection	7909568
109751325	109751348	1	-	27260156	NCIH1373	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.10863413834435748	[627]	[720,563,743,155]	-1	hSpCas9	negative selection	7966552
109751326	109751349	1	+	27260156	NCIH1373	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.41158857402797855	[804]	[479,310,485,392]	-4	hSpCas9	negative selection	7966553
109750736	109750759	1	-	27260156	NCIH1373	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.07634320155619168	[723]	[864,748,982,217]	0	hSpCas9	negative selection	7966554
109750749	109750772	1	+	27260156	NCIH1373	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.12478161292304513	[893]	[1063,933,1072,346]	1	hSpCas9	negative selection	8030817
109753174	109753197	1	+	27260156	NCIH1373	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.36310063733427334	[439]	[649,340,1022,141]	3	hSpCas9	negative selection	8030818
109753184	109753207	1	-	27260156	NCIH1373	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.22255797269013644	[651]	[1033,867,758,201]	2	hSpCas9	negative selection	8030819
109751325	109751348	1	-	27260156	PATU8902	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.20570332093745403	[627]	[839,967,601,643]	-2	hSpCas9	negative selection	8087803
109751326	109751349	1	+	27260156	PATU8902	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.7874084132549231	[804]	[972,409,533,707]	-6	hSpCas9	negative selection	8087804
109750736	109750759	1	-	27260156	PATU8902	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.15215132133270914	[723]	[1267,1092,477,1890]	1	hSpCas9	negative selection	8087805
109750749	109750772	1	+	27260156	PATU8902	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.08746217035598824	[893]	[1171,2053,560,1746]	0	hSpCas9	negative selection	8152068
109753174	109753197	1	+	27260156	PATU8902	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.11314708394004275	[439]	[868,657,459,714]	1	hSpCas9	negative selection	8152069
109753184	109753207	1	-	27260156	PATU8902	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.7749519468405002	[651]	[2297,1304,1468,1085]	7	hSpCas9	negative selection	8152070
109751325	109751348	1	-	27260156	PANC1	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.02675767554255809	[627]	[499,600,639,472]	0	hSpCas9	negative selection	8209054
109751326	109751349	1	+	27260156	PANC1	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.5090435964731859	[804]	[493,435,581,423]	-6	hSpCas9	negative selection	8209055
109750736	109750759	1	-	27260156	PANC1	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.020343290024688265	[723]	[644,588,619,586]	0	hSpCas9	negative selection	8209056
109750749	109750772	1	+	27260156	PANC1	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.07469371285297322	[893]	[568,1034,690,682]	-1	hSpCas9	negative selection	8273319
109753174	109753197	1	+	27260156	PANC1	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.06548921753726002	[439]	[295,468,426,399]	1	hSpCas9	negative selection	8273320
109753184	109753207	1	-	27260156	PANC1	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.3465083370478593	[651]	[607,914,805,574]	5	hSpCas9	negative selection	8273321
109751325	109751348	1	-	27260156	PANC0813	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.1257064657938814	[627]	[721,752,656,1062]	2	hSpCas9	negative selection	8330305
109751326	109751349	1	+	27260156	PANC0813	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	0.08337581121532844	[804]	[1314,787,1024,911]	1	hSpCas9	negative selection	8330306
109750736	109750759	1	-	27260156	PANC0813	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	0.03336491446679646	[723]	[1042,778,895,782]	0	hSpCas9	negative selection	8330307
109750749	109750772	1	+	27260156	PANC0813	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.0635498622922932	[893]	[1169,1180,1034,1012]	1	hSpCas9	negative selection	8394570
109753174	109753197	1	+	27260156	PANC0813	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.16121795793635815	[439]	[684,538,561,536]	2	hSpCas9	negative selection	8394571
109753184	109753207	1	-	27260156	PANC0813	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.04727577309022213	[651]	[841,743,775,805]	0	hSpCas9	negative selection	8394572
109751325	109751348	1	-	27260156	RDES	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.2686504870995901	[627]	[608,814,911,1239]	4	hSpCas9	negative selection	8451556
109751326	109751349	1	+	27260156	RDES	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.8533339183846993	[804]	[431,634,471,494]	-8	hSpCas9	negative selection	8451557
109750736	109750759	1	-	27260156	RDES	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.17647419126245867	[723]	[616,688,761,914]	-3	hSpCas9	negative selection	8451558
109750749	109750772	1	+	27260156	RDES	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.042253169834367665	[893]	[873,882,1202,1349]	0	hSpCas9	negative selection	8515821
109753174	109753197	1	+	27260156	RDES	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.46189927106864415	[439]	[589,682,672,869]	7	hSpCas9	negative selection	8515822
109753184	109753207	1	-	27260156	RDES	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.4552470485041067	[651]	[1015,858,1161,1070]	7	hSpCas9	negative selection	8515823
109751325	109751348	1	-	27260156	PC3	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.2902862787116261	[627]	[385,895,1499,657]	6	hSpCas9	negative selection	8572807
109751326	109751349	1	+	27260156	PC3	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.1578429370651777	[804]	[424,627,1356,786]	-4	hSpCas9	negative selection	8572808
109750736	109750759	1	-	27260156	PC3	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.08152551150535248	[723]	[369,701,1102,798]	-2	hSpCas9	negative selection	8572809
109750749	109750772	1	+	27260156	PC3	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.09472667294707238	[893]	[599,812,1183,890]	-2	hSpCas9	negative selection	8637072
109753174	109753197	1	+	27260156	PC3	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.03549476910530908	[439]	[280,458,791,427]	0	hSpCas9	negative selection	8637073
109753184	109753207	1	-	27260156	PC3	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.10084906294535967	[651]	[468,655,1294,627]	2	hSpCas9	negative selection	8637074
109751325	109751348	1	-	27260156	PATU8988T	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.3481167171798849	[627]	[526,391,566,405]	-5	hSpCas9	negative selection	8694058
109751326	109751349	1	+	27260156	PATU8988T	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.07768421912385659	[804]	[631,758,743,821]	-1	hSpCas9	negative selection	8694059
109750736	109750759	1	-	27260156	PATU8988T	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.2037008985357534	[723]	[523,300,759,831]	-3	hSpCas9	negative selection	8694060
109750749	109750772	1	+	27260156	PATU8988T	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	0.2929746018515206	[893]	[1013,1173,851,1219]	5	hSpCas9	negative selection	8758323
109753174	109753197	1	+	27260156	PATU8988T	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.196544309191625	[439]	[574,330,661,352]	3	hSpCas9	negative selection	8758324
109753184	109753207	1	-	27260156	PATU8988T	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.10250005162114639	[651]	[694,687,559,772]	1	hSpCas9	negative selection	8758325
109751325	109751348	1	-	27260156	T47D	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.12458652413137744	[627]	[726,775,772,919]	2	hSpCas9	negative selection	8815309
109751326	109751349	1	+	27260156	T47D	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.3253197709884029	[804]	[781,688,647,885]	-6	hSpCas9	negative selection	8815310
109750736	109750759	1	-	27260156	T47D	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.03609086990912025	[723]	[901,740,820,833]	-1	hSpCas9	negative selection	8815311
109750749	109750772	1	+	27260156	T47D	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.07465835321499503	[893]	[1068,1030,827,1027]	-2	hSpCas9	negative selection	8879574
109753174	109753197	1	+	27260156	T47D	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.18066140271425177	[439]	[666,481,568,615]	4	hSpCas9	negative selection	8879575
109753184	109753207	1	-	27260156	T47D	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.21273504467090953	[651]	[1000,863,803,853]	4	hSpCas9	negative selection	8879576
109751325	109751348	1	-	27260156	SU8686	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.2062461751356173	[627]	[553,538,516,542]	-4	hSpCas9	negative selection	8936560
109751326	109751349	1	+	27260156	SU8686	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.2618158206200776	[804]	[656,569,571,908]	-4	hSpCas9	negative selection	8936561
109750736	109750759	1	-	27260156	SU8686	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.06648830384536464	[723]	[581,618,779,796]	-1	hSpCas9	negative selection	8936562
109750749	109750772	1	+	27260156	SU8686	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.17541118252555432	[893]	[857,669,718,911]	-3	hSpCas9	negative selection	9000825
109753174	109753197	1	+	27260156	SU8686	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	-0.0725349620404619	[439]	[251,427,463,552]	-1	hSpCas9	negative selection	9000826
109753184	109753207	1	-	27260156	SU8686	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.11348609744982296	[651]	[680,695,687,734]	2	hSpCas9	negative selection	9000827
109751325	109751348	1	-	27260156	SKES1	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.049258379970763544	[627]	[792,553,783,481]	1	hSpCas9	negative selection	9057811
109751326	109751349	1	+	27260156	SKES1	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.3517743039244264	[804]	[713,557,656,588]	-7	hSpCas9	negative selection	9057812
109750736	109750759	1	-	27260156	SKES1	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.0800887361005791	[723]	[805,645,809,496]	-2	hSpCas9	negative selection	9057813
109750749	109750772	1	+	27260156	SKES1	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.16956779324570226	[893]	[789,1042,633,734]	-4	hSpCas9	negative selection	9122076
109753174	109753197	1	+	27260156	SKES1	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.37864188724598496	[439]	[505,585,669,512]	7	hSpCas9	negative selection	9122077
109753184	109753207	1	-	27260156	SKES1	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.27428474086955945	[651]	[959,828,794,604]	6	hSpCas9	negative selection	9122078
109751325	109751348	1	-	27260156	TOV112D	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.18774764886029308	[627]	[576,661,442,554]	-4	hSpCas9	negative selection	9179062
109751326	109751349	1	+	27260156	TOV112D	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.2975140496502651	[804]	[712,830,622,507]	-5	hSpCas9	negative selection	9179063
109750736	109750759	1	-	27260156	TOV112D	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.21932501797562076	[723]	[477,664,520,818]	-4	hSpCas9	negative selection	9179064
109750749	109750772	1	+	27260156	TOV112D	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.21606997092030633	[893]	[818,1168,528,669]	-4	hSpCas9	negative selection	9243327
109753174	109753197	1	+	27260156	TOV112D	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.03101444226356566	[439]	[489,443,486,382]	0	hSpCas9	negative selection	9243328
109753184	109753207	1	-	27260156	TOV112D	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.33400614208115276	[651]	[828,709,582,1132]	6	hSpCas9	negative selection	9243329
109751325	109751348	1	-	27260156	TC71	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	-0.11507268911712137	[627]	[640,691,649,493]	-3	hSpCas9	negative selection	9300313
109751326	109751349	1	+	27260156	TC71	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.2976541596245271	[804]	[766,726,638,673]	-7	hSpCas9	negative selection	9300314
109750736	109750759	1	-	27260156	TC71	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.37965918638576024	[723]	[587,521,592,688]	-8	hSpCas9	negative selection	9300315
109750749	109750772	1	+	27260156	TC71	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.024474240682710313	[893]	[974,989,838,968]	0	hSpCas9	negative selection	9364578
109753174	109753197	1	+	27260156	TC71	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.15617898074634762	[439]	[505,500,501,598]	4	hSpCas9	negative selection	9364579
109753184	109753207	1	-	27260156	TC71	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.22530777338701102	[651]	[781,881,736,873]	5	hSpCas9	negative selection	9364580
109751325	109751348	1	-	27260156	TC32	viability	CAATGCTTCGACTTAGCTCGAGG	EPS8L3	ENSG00000198758	0.38629331711097575	[627]	[813,736,768,717]	6	hSpCas9	negative selection	9421564
109751326	109751349	1	+	27260156	TC32	viability	CTCGAGCTAAGTCGAAGCATTGG	EPS8L3	ENSG00000198758	-0.23848689340873297	[804]	[517,497,945,690]	-4	hSpCas9	negative selection	9421565
109750736	109750759	1	-	27260156	TC32	viability	CAGCTACTTCGCATAAGACCTGG	EPS8L3	ENSG00000198758	-0.0293884010072476	[723]	[732,501,765,696]	0	hSpCas9	negative selection	9421566
109750749	109750772	1	+	27260156	TC32	viability	GAAGTAGCTGGCTCCCCGTCAGG	EPS8L3	ENSG00000198758	-0.07295635448257198	[893]	[759,610,929,952]	-1	hSpCas9	negative selection	9485829
109753174	109753197	1	+	27260156	TC32	viability	GGGCTCATCGCCTGTCCAGTCGG	EPS8L3	ENSG00000198758	0.22396151878369064	[439]	[519,325,689,455]	4	hSpCas9	negative selection	9485830
109753184	109753207	1	-	27260156	TC32	viability	CTCTTCAGGGCCGACTGGACAGG	EPS8L3	ENSG00000198758	0.49266705996404103	[651]	[884,557,1160,963]	8	hSpCas9	negative selection	9485831
109757480	109757503	1	+	27869803	HPAFII	viability after 27 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.5688979170231003	[514]	[357,437,NaN]	4	hSpCas9	negative selection	9527763
109758383	109758406	1	+	27869803	HPAFII	viability after 27 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.3203705615772934	[501]	[454,224,NaN]	2	hSpCas9	negative selection	9527765
109758580	109758603	1	+	27869803	HPAFII	viability after 27 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.9904052247180957	[720]	[907,623,NaN]	7	hSpCas9	negative selection	9527766
109759288	109759311	1	+	27869803	HPAFII	viability after 27 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-1.9417269584246584	[278]	[59,19,NaN]	-8	hSpCas9	negative selection	9527767
109759752	109759775	1	-	27869803	HPAFII	viability after 27 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.23020133314816715	[304]	[132,233,NaN]	1	hSpCas9	negative selection	9527768
109761548	109761571	1	-	27869803	HPAFII	viability after 27 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	1.2102946690102927	[138]	[185,154,NaN]	8	hSpCas9	negative selection	9527769
109757480	109757503	1	+	27869803	HPAFII	viability after 15 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	-0.1296259561681945	[514]	[582,457,NaN]	-1	hSpCas9	negative selection	9610212
109758383	109758406	1	+	27869803	HPAFII	viability after 15 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.1979220663017941	[501]	[835,242,NaN]	-2	hSpCas9	negative selection	9610214
109758580	109758603	1	+	27869803	HPAFII	viability after 15 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.5709641794871385	[720]	[1644,843,NaN]	6	hSpCas9	negative selection	9610215
109759288	109759311	1	+	27869803	HPAFII	viability after 15 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-1.1307334602829773	[278]	[168,116,NaN]	-8	hSpCas9	negative selection	9610216
109759752	109759775	1	-	27869803	HPAFII	viability after 15 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.5831102116821907	[304]	[314,158,NaN]	-6	hSpCas9	negative selection	9610217
109761548	109761571	1	-	27869803	HPAFII	viability after 15 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.6203343293284074	[138]	[331,165,NaN]	7	hSpCas9	negative selection	9610218
109757480	109757503	1	+	27869803	ASPC1	viability after 36 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.039868865371511575	[1125]	[519,444,285]	0	hSpCas9	negative selection	9692661
109758383	109758406	1	+	27869803	ASPC1	viability after 36 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.14153233295433776	[1158]	[278,614,424]	1	hSpCas9	negative selection	9692663
109758580	109758603	1	+	27869803	ASPC1	viability after 36 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	-0.20567005248694747	[1700]	[637,611,345]	-2	hSpCas9	negative selection	9692664
109759288	109759311	1	+	27869803	ASPC1	viability after 36 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-1.1082956427644015	[474]	[93,37,94]	-8	hSpCas9	negative selection	9692665
109759752	109759775	1	-	27869803	ASPC1	viability after 36 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.9443826694741707	[613]	[48,99,162]	-7	hSpCas9	negative selection	9692666
109761548	109761571	1	-	27869803	ASPC1	viability after 36 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.9743219768564834	[307]	[297,58,268]	8	hSpCas9	negative selection	9692667
109757480	109757503	1	+	27869803	PATU8988S	viability after 35 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.2974689777945049	[986]	[505,470,NaN]	3	hSpCas9	negative selection	9775110
109758383	109758406	1	+	27869803	PATU8988S	viability after 35 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.02311260082948685	[1143]	[419,486,NaN]	0	hSpCas9	negative selection	9775112
109758580	109758603	1	+	27869803	PATU8988S	viability after 35 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.10176153463589221	[1423]	[803,425,NaN]	1	hSpCas9	negative selection	9775113
109759288	109759311	1	+	27869803	PATU8988S	viability after 35 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	0.06995834351638633	[438]	[225,144,NaN]	0	hSpCas9	negative selection	9775114
109759752	109759775	1	-	27869803	PATU8988S	viability after 35 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.0597567122688725	[482]	[245,126,NaN]	0	hSpCas9	negative selection	9775115
109761548	109761571	1	-	27869803	PATU8988S	viability after 35 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.447198104881156	[313]	[136,207,NaN]	5	hSpCas9	negative selection	9775116
109757480	109757503	1	+	27869803	PATU8988S	viability after 31 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.2050930334846771	[986]	[454,451,NaN]	2	hSpCas9	negative selection	9857559
109758383	109758406	1	+	27869803	PATU8988S	viability after 31 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.46009617700216654	[1143]	[590,673,NaN]	5	hSpCas9	negative selection	9857561
109758580	109758603	1	+	27869803	PATU8988S	viability after 31 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.09216841805119258	[1423]	[555,667,NaN]	1	hSpCas9	negative selection	9857562
109759288	109759311	1	+	27869803	PATU8988S	viability after 31 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-0.0789570669472725	[438]	[192,130,NaN]	-1	hSpCas9	negative selection	9857563
109759752	109759775	1	-	27869803	PATU8988S	viability after 31 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	-0.3948451546472126	[482]	[149,141,NaN]	-4	hSpCas9	negative selection	9857564
109761548	109761571	1	-	27869803	PATU8988S	viability after 31 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.21407749738839466	[313]	[113,184,NaN]	2	hSpCas9	negative selection	9857565
109757480	109757503	1	+	27869803	HPAFII	viability after 35 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.8476024571868295	[514]	[320,635,NaN]	5	hSpCas9	negative selection	9940008
109758383	109758406	1	+	27869803	HPAFII	viability after 35 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	-0.14545328752915887	[501]	[225,233,NaN]	-1	hSpCas9	negative selection	9940010
109758580	109758603	1	+	27869803	HPAFII	viability after 35 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	1.2681276058353101	[720]	[975,769,NaN]	8	hSpCas9	negative selection	9940011
109759288	109759311	1	+	27869803	HPAFII	viability after 35 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-2.5011448435133636	[278]	[39,7,NaN]	-8	hSpCas9	negative selection	9940012
109759752	109759775	1	-	27869803	HPAFII	viability after 35 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.8840811546988905	[304]	[220,356,NaN]	6	hSpCas9	negative selection	9940013
109761548	109761571	1	-	27869803	HPAFII	viability after 35 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	1.588483424106998	[138]	[157,271,NaN]	9	hSpCas9	negative selection	9940014
109757480	109757503	1	+	27869803	HPAFII	viability after 31 days	CGAAGTTCAGGGACTTGAAGAGG	EPS8L3	ENSG00000198758	0.4381532170539997	[514]	[281,510,NaN]	3	hSpCas9	negative selection	10022457
109758383	109758406	1	+	27869803	HPAFII	viability after 31 days	TCTCGGGCACTGGTGTGGCGTGG	EPS8L3	ENSG00000198758	0.03407654774134161	[501]	[376,191,NaN]	0	hSpCas9	negative selection	10022459
109758580	109758603	1	+	27869803	HPAFII	viability after 31 days	CGTGCCTGCTCCATAGGGAGCGG	EPS8L3	ENSG00000198758	0.9705368587758509	[720]	[790,794,NaN]	7	hSpCas9	negative selection	10022460
109759288	109759311	1	+	27869803	HPAFII	viability after 31 days	GCTCCTGCACGGTGATGGACAGG	EPS8L3	ENSG00000198758	-2.4007899124952883	[278]	[32,25,NaN]	-8	hSpCas9	negative selection	10022461
109759752	109759775	1	-	27869803	HPAFII	viability after 31 days	GCTGTTCGAGATGGATGCACAGG	EPS8L3	ENSG00000198758	0.49273966610948716	[304]	[192,292,NaN]	3	hSpCas9	negative selection	10022462
109761548	109761571	1	-	27869803	HPAFII	viability after 31 days	TGCCCTTGTAGTGCACCGGAAGG	EPS8L3	ENSG00000198758	0.8369993191681971	[138]	[135,142,NaN]	6	hSpCas9	negative selection	10022463
109761512	109761535	1	+	28162770	P31FUJ	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-1.0263513269469517	[25]	[14]	-6	hSpCas9	negative selection	10150824
109757039	109757062	1	-	28162770	P31FUJ	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	1.1095899930326996	[27]	[70]	9	hSpCas9	negative selection	10150825
109759795	109759818	1	-	28162770	P31FUJ	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-2.113220588661706	[80]	[21]	-8	hSpCas9	negative selection	10150826
109759069	109759092	1	-	28162770	P31FUJ	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	10150827
109758389	109758412	1	+	28162770	P31FUJ	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.39946601108513424	[519]	[805]	4	hSpCas9	negative selection	10150828
109758341	109758364	1	+	28162770	P31FUJ	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	-0.10604506212843981	[195]	[213]	-1	hSpCas9	negative selection	10150829
109757995	109758018	1	-	28162770	P31FUJ	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-1.7525805363753972	[237]	[82]	-8	hSpCas9	negative selection	10150830
109752015	109752038	1	-	28162770	P31FUJ	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-4.554730299301741	[19]	[0]	-9	hSpCas9	negative selection	10150831
109751737	109751760	1	-	28162770	P31FUJ	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.9390710013576682	[247]	[75]	-8	hSpCas9	negative selection	10150832
109758537	109758560	1	-	28162770	P31FUJ	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.2807756630700122	[579]	[827]	3	hSpCas9	negative selection	10150833
109761512	109761535	1	+	28162770	TF1	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10320190
109757039	109757062	1	-	28162770	TF1	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10320191
109759795	109759818	1	-	28162770	TF1	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10320192
109759069	109759092	1	-	28162770	TF1	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10320193
109758389	109758412	1	+	28162770	TF1	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[543]	1	hSpCas9	negative selection	10320194
109758341	109758364	1	+	28162770	TF1	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10320195
109757995	109758018	1	-	28162770	TF1	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[16]	1	hSpCas9	negative selection	10320196
109752015	109752038	1	-	28162770	TF1	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10320197
109751737	109751760	1	-	28162770	TF1	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10320198
109758537	109758560	1	-	28162770	TF1	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	NaN	[NaN]	[458]	1	hSpCas9	negative selection	10320199
109761512	109761535	1	+	28162770	SKM1	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-2.748001116578229	[18]	[4]	-9	hSpCas9	negative selection	10489556
109757039	109757062	1	-	28162770	SKM1	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-1.6699986045769561	[8]	[4]	-8	hSpCas9	negative selection	10489557
109759795	109759818	1	-	28162770	SKM1	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-2.143929792909368	[34]	[13]	-8	hSpCas9	negative selection	10489558
109759069	109759092	1	-	28162770	SKM1	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10489559
109758389	109758412	1	+	28162770	SKM1	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	-0.0886473574081783	[159]	[265]	0	hSpCas9	negative selection	10489560
109758341	109758364	1	+	28162770	SKM1	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	1.2640692521016623	[60]	[258]	9	hSpCas9	negative selection	10489561
109757995	109758018	1	-	28162770	SKM1	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-2.002573943663826	[33]	[14]	-8	hSpCas9	negative selection	10489562
109752015	109752038	1	-	28162770	SKM1	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-0.8220016980220062	[4]	[4]	-6	hSpCas9	negative selection	10489563
109751737	109751760	1	-	28162770	SKM1	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.4740783946016986	[65]	[41]	-7	hSpCas9	negative selection	10489564
109758537	109758560	1	-	28162770	SKM1	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	-0.43497857491275804	[142]	[186]	-4	hSpCas9	negative selection	10489565
109761512	109761535	1	+	28162770	SKM1	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-2.748001116578229	[18]	[4]	-9	hSpCas9	negative selection	10658922
109757039	109757062	1	-	28162770	SKM1	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-1.6699986045769561	[8]	[4]	-8	hSpCas9	negative selection	10658923
109759795	109759818	1	-	28162770	SKM1	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-2.143929792909368	[34]	[13]	-8	hSpCas9	negative selection	10658924
109759069	109759092	1	-	28162770	SKM1	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10658925
109758389	109758412	1	+	28162770	SKM1	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	-0.0886473574081783	[159]	[265]	0	hSpCas9	negative selection	10658926
109758341	109758364	1	+	28162770	SKM1	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	1.2640692521016623	[60]	[258]	9	hSpCas9	negative selection	10658927
109757995	109758018	1	-	28162770	SKM1	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-2.002573943663826	[33]	[14]	-8	hSpCas9	negative selection	10658928
109752015	109752038	1	-	28162770	SKM1	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-0.8220016980220062	[4]	[4]	-6	hSpCas9	negative selection	10658929
109751737	109751760	1	-	28162770	SKM1	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.4740783946016986	[65]	[41]	-7	hSpCas9	negative selection	10658930
109758537	109758560	1	-	28162770	SKM1	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	-0.43497857491275804	[142]	[186]	-4	hSpCas9	negative selection	10658931
109761512	109761535	1	+	28162770	PL21	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-0.19578906184181877	[49]	[18]	-1	hSpCas9	negative selection	10828288
109757039	109757062	1	-	28162770	PL21	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	0.49969989634822776	[25]	[15]	4	hSpCas9	negative selection	10828289
109759795	109759818	1	-	28162770	PL21	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-0.38482288623183614	[89]	[29]	-3	hSpCas9	negative selection	10828290
109759069	109759092	1	-	28162770	PL21	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10828291
109758389	109758412	1	+	28162770	PL21	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.2203174964269503	[567]	[287]	2	hSpCas9	negative selection	10828292
109758341	109758364	1	+	28162770	PL21	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	0.490654756745221	[259]	[158]	4	hSpCas9	negative selection	10828293
109757995	109758018	1	-	28162770	PL21	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-0.29555554813474877	[140]	[49]	-2	hSpCas9	negative selection	10828294
109752015	109752038	1	-	28162770	PL21	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-2.7998603855106805	[15]	[0]	-9	hSpCas9	negative selection	10828295
109751737	109751760	1	-	28162770	PL21	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.6873856562522673	[184]	[24]	-8	hSpCas9	negative selection	10828296
109758537	109758560	1	-	28162770	PL21	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.30984353391505026	[442]	[238]	2	hSpCas9	negative selection	10828297
109761512	109761535	1	+	28162770	P31FUJ	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-1.0263513269469517	[25]	[14]	-6	hSpCas9	negative selection	10997654
109757039	109757062	1	-	28162770	P31FUJ	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	1.1095899930326996	[27]	[70]	9	hSpCas9	negative selection	10997655
109759795	109759818	1	-	28162770	P31FUJ	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-2.113220588661706	[80]	[21]	-8	hSpCas9	negative selection	10997656
109759069	109759092	1	-	28162770	P31FUJ	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	10997657
109758389	109758412	1	+	28162770	P31FUJ	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.39946601108513424	[519]	[805]	4	hSpCas9	negative selection	10997658
109758341	109758364	1	+	28162770	P31FUJ	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	-0.10604506212843981	[195]	[213]	-1	hSpCas9	negative selection	10997659
109757995	109758018	1	-	28162770	P31FUJ	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-1.7525805363753972	[237]	[82]	-8	hSpCas9	negative selection	10997660
109752015	109752038	1	-	28162770	P31FUJ	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-4.554730299301741	[19]	[0]	-9	hSpCas9	negative selection	10997661
109751737	109751760	1	-	28162770	P31FUJ	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.9390710013576682	[247]	[75]	-8	hSpCas9	negative selection	10997662
109758537	109758560	1	-	28162770	P31FUJ	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.2807756630700122	[579]	[827]	3	hSpCas9	negative selection	10997663
109761512	109761535	1	+	28162770	OCIAML5	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-2.568273604863405	[22]	[6]	-8	hSpCas9	negative selection	11167020
109757039	109757062	1	-	28162770	OCIAML5	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	0.4537418586600881	[35]	[88]	4	hSpCas9	negative selection	11167021
109759795	109759818	1	-	28162770	OCIAML5	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-2.5890321650302033	[49]	[14]	-8	hSpCas9	negative selection	11167022
109759069	109759092	1	-	28162770	OCIAML5	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11167023
109758389	109758412	1	+	28162770	OCIAML5	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	-0.05137537908740364	[247]	[431]	0	hSpCas9	negative selection	11167024
109758341	109758364	1	+	28162770	OCIAML5	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	-0.2605314162193546	[145]	[219]	-2	hSpCas9	negative selection	11167025
109757995	109758018	1	-	28162770	OCIAML5	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-2.9181557613217697	[66]	[15]	-8	hSpCas9	negative selection	11167026
109752015	109752038	1	-	28162770	OCIAML5	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	1.1479334291360033	[3]	[15]	8	hSpCas9	negative selection	11167027
109751737	109751760	1	-	28162770	OCIAML5	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.8283505018901893	[180]	[91]	-7	hSpCas9	negative selection	11167028
109758537	109758560	1	-	28162770	OCIAML5	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.42222695238448094	[233]	[565]	3	hSpCas9	negative selection	11167029
109761512	109761535	1	+	28162770	EOL1	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-0.6795235520983263	[75]	[24]	-5	hSpCas9	negative selection	11336386
109757039	109757062	1	-	28162770	EOL1	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	0.6875085742696854	[32]	[27]	6	hSpCas9	negative selection	11336387
109759795	109759818	1	-	28162770	EOL1	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-0.6211018051257954	[180]	[61]	-4	hSpCas9	negative selection	11336388
109759069	109759092	1	-	28162770	EOL1	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	0.924547771570535	[0]	[0]	7	hSpCas9	negative selection	11336389
109758389	109758412	1	+	28162770	EOL1	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.06547781296877497	[993]	[547]	0	hSpCas9	negative selection	11336390
109758341	109758364	1	+	28162770	EOL1	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	-0.9854420626968705	[465]	[123]	-6	hSpCas9	negative selection	11336391
109757995	109758018	1	-	28162770	EOL1	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-3.6079473092564864	[161]	[6]	-9	hSpCas9	negative selection	11336392
109752015	109752038	1	-	28162770	EOL1	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	-1.7758919465705576	[25]	[3]	-8	hSpCas9	negative selection	11336393
109751737	109751760	1	-	28162770	EOL1	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.53696415750781	[346]	[62]	-7	hSpCas9	negative selection	11336394
109758537	109758560	1	-	28162770	EOL1	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	-0.1364202457208925	[579]	[277]	-1	hSpCas9	negative selection	11336395
109761512	109761535	1	+	28162770	MOLM13	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	0.24549696020813094	[55]	[47]	1	hSpCas9	negative selection	11505752
109757039	109757062	1	-	28162770	MOLM13	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-3.576504737813875	[32]	[1]	-8	hSpCas9	negative selection	11505753
109759795	109759818	1	-	28162770	MOLM13	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-0.70614001823047	[87]	[38]	-4	hSpCas9	negative selection	11505754
109759069	109759092	1	-	28162770	MOLM13	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	0.4678893815445777	[0]	[0]	3	hSpCas9	negative selection	11505755
109758389	109758412	1	+	28162770	MOLM13	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.4444684931428269	[620]	[610]	3	hSpCas9	negative selection	11505756
109758341	109758364	1	+	28162770	MOLM13	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	0.4600057824687456	[366]	[364]	3	hSpCas9	negative selection	11505757
109757995	109758018	1	-	28162770	MOLM13	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-1.702035619897733	[170]	[37]	-7	hSpCas9	negative selection	11505758
109752015	109752038	1	-	28162770	MOLM13	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	1.3018794301056498	[22]	[40]	8	hSpCas9	negative selection	11505759
109751737	109751760	1	-	28162770	MOLM13	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-6.894054392190663	[328]	[1]	-9	hSpCas9	negative selection	11505760
109758537	109758560	1	-	28162770	MOLM13	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	-0.003765813350474545	[562]	[405]	0	hSpCas9	negative selection	11505761
109761512	109761535	1	+	28162770	HEL	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-3.783525922701741	[42]	[1]	-9	hSpCas9	negative selection	11675118
109757039	109757062	1	-	28162770	HEL	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-0.6598239380200743	[36]	[14]	-4	hSpCas9	negative selection	11675119
109759795	109759818	1	-	28162770	HEL	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-1.5207599002825223	[111]	[24]	-7	hSpCas9	negative selection	11675120
109759069	109759092	1	-	28162770	HEL	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-0.3572611679996429	[1]	[0]	-2	hSpCas9	negative selection	11675121
109758389	109758412	1	+	28162770	HEL	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.26580593774701544	[547]	[421]	2	hSpCas9	negative selection	11675122
109758341	109758364	1	+	28162770	HEL	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	-0.10619940383192522	[362]	[215]	-1	hSpCas9	negative selection	11675123
109757995	109758018	1	-	28162770	HEL	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-2.772298667278487	[127]	[11]	-8	hSpCas9	negative selection	11675124
109752015	109752038	1	-	28162770	HEL	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	0.34317855014144927	[15]	[12]	3	hSpCas9	negative selection	11675125
109751737	109751760	1	-	28162770	HEL	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-2.322495749838966	[327]	[41]	-8	hSpCas9	negative selection	11675126
109758537	109758560	1	-	28162770	HEL	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	-0.044630817694370495	[466]	[289]	0	hSpCas9	negative selection	11675127
109761512	109761535	1	+	28162770	MV411	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-0.5301700278807768	[23]	[13]	-4	hSpCas9	negative selection	11844484
109757039	109757062	1	-	28162770	MV411	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-0.6821731213258269	[39]	[20]	-5	hSpCas9	negative selection	11844485
109759795	109759818	1	-	28162770	MV411	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-2.685448253358688	[83]	[10]	-9	hSpCas9	negative selection	11844486
109759069	109759092	1	-	28162770	MV411	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11844487
109758389	109758412	1	+	28162770	MV411	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.2985620157604496	[498]	[516]	2	hSpCas9	negative selection	11844488
109758341	109758364	1	+	28162770	MV411	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	1.0897561450952102	[197]	[354]	8	hSpCas9	negative selection	11844489
109757995	109758018	1	-	28162770	MV411	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-0.2379892763874666	[118]	[84]	-2	hSpCas9	negative selection	11844490
109752015	109752038	1	-	28162770	MV411	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	1.077512549340463	[17]	[31]	8	hSpCas9	negative selection	11844491
109751737	109751760	1	-	28162770	MV411	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-2.996016486081502	[160]	[16]	-9	hSpCas9	negative selection	11844492
109758537	109758560	1	-	28162770	MV411	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.38535215732246675	[318]	[350]	3	hSpCas9	negative selection	11844493
109761512	109761535	1	+	28162770	MONOMAC1	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-2.197036847059554	[23]	[5]	-9	hSpCas9	negative selection	12013850
109757039	109757062	1	-	28162770	MONOMAC1	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	0.7155003116901066	[16]	[31]	6	hSpCas9	negative selection	12013851
109759795	109759818	1	-	28162770	MONOMAC1	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	0.2623947715777437	[55]	[76]	2	hSpCas9	negative selection	12013852
109759069	109759092	1	-	28162770	MONOMAC1	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	12013853
109758389	109758412	1	+	28162770	MONOMAC1	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	-0.07330147863730874	[334]	[364]	0	hSpCas9	negative selection	12013854
109758341	109758364	1	+	28162770	MONOMAC1	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	0.4002039834400392	[116]	[176]	4	hSpCas9	negative selection	12013855
109757995	109758018	1	-	28162770	MONOMAC1	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-0.25909781519180514	[94]	[90]	-2	hSpCas9	negative selection	12013856
109752015	109752038	1	-	28162770	MONOMAC1	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	0.4403930735557382	[8]	[13]	4	hSpCas9	negative selection	12013857
109751737	109751760	1	-	28162770	MONOMAC1	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-0.09750117350863921	[125]	[134]	-1	hSpCas9	negative selection	12013858
109758537	109758560	1	-	28162770	MONOMAC1	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	-0.20853248589738327	[251]	[249]	-2	hSpCas9	negative selection	12013859
109761512	109761535	1	+	28162770	OCIAML2	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-1.1169928706274606	[8]	[22]	-6	hSpCas9	negative selection	12183216
109757039	109757062	1	-	28162770	OCIAML2	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	0.11433267547899462	[1]	[11]	1	hSpCas9	negative selection	12183217
109759795	109759818	1	-	28162770	OCIAML2	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-0.5230972451362966	[20]	[80]	-4	hSpCas9	negative selection	12183218
109759069	109759092	1	-	28162770	OCIAML2	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12183219
109758389	109758412	1	+	28162770	OCIAML2	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.7488153120439498	[69]	[651]	7	hSpCas9	negative selection	12183220
109758341	109758364	1	+	28162770	OCIAML2	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	0.5345134780337983	[34]	[280]	5	hSpCas9	negative selection	12183221
109757995	109758018	1	-	28162770	OCIAML2	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-1.4706298252421615	[24]	[49]	-7	hSpCas9	negative selection	12183222
109752015	109752038	1	-	28162770	OCIAML2	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	0.031870515287022005	[2]	[16]	0	hSpCas9	negative selection	12183223
109751737	109751760	1	-	28162770	OCIAML2	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-3.979643472730019	[36]	[12]	-9	hSpCas9	negative selection	12183224
109758537	109758560	1	-	28162770	OCIAML2	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.7541027345488033	[65]	[616]	7	hSpCas9	negative selection	12183225
109761512	109761535	1	+	28162770	OCIAML3	viability	GGAGGGTGGGCTCTGAGGTGAGG	EPS8L3	ENSG00000198758	-0.8097363313796004	[17]	[30]	-6	hSpCas9	negative selection	12352582
109757039	109757062	1	-	28162770	OCIAML3	viability	GAGTAACCTTTGGATGGGGTTGG	EPS8L3	ENSG00000198758	-2.079434467494405	[6]	[4]	-8	hSpCas9	negative selection	12352583
109759795	109759818	1	-	28162770	OCIAML3	viability	AGGGGAGTCAGAGAGTCCAGGGG	EPS8L3	ENSG00000198758	-0.03761429179977771	[16]	[49]	0	hSpCas9	negative selection	12352584
109759069	109759092	1	-	28162770	OCIAML3	viability	GAAGGCTCTGGAGGAAGAGCTGG	EPS8L3	ENSG00000198758	-2.594007640324163	[1]	[0]	-9	hSpCas9	negative selection	12352585
109758389	109758412	1	+	28162770	OCIAML3	viability	GCACTGGTGTGGCGTGGCAGGGG	EPS8L3	ENSG00000198758	0.11206394589625912	[117]	[384]	1	hSpCas9	negative selection	12352586
109758341	109758364	1	+	28162770	OCIAML3	viability	GAAGAGGACCGCCTTGGAGGAGG	EPS8L3	ENSG00000198758	0.0005409092261909887	[49]	[150]	0	hSpCas9	negative selection	12352587
109757995	109758018	1	-	28162770	OCIAML3	viability	GGGAAAGCTGGAGAAGGCCCAGG	EPS8L3	ENSG00000198758	-2.066076084639386	[42]	[30]	-8	hSpCas9	negative selection	12352588
109752015	109752038	1	-	28162770	OCIAML3	viability	GAACCCACGGGAACTGACTGTGG	EPS8L3	ENSG00000198758	0.6790108540822528	[5]	[28]	6	hSpCas9	negative selection	12352589
109751737	109751760	1	-	28162770	OCIAML3	viability	GTGGCTGGTGAAGAATGAGGCGG	EPS8L3	ENSG00000198758	-1.169122355088972	[72]	[97]	-7	hSpCas9	negative selection	12352590
109758537	109758560	1	-	28162770	OCIAML3	viability	CTCCAGAACAGCCCCACCAGAGG	EPS8L3	ENSG00000198758	0.6348110501717178	[95]	[449]	6	hSpCas9	negative selection	12352591