Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3266
• Symbol:ERAS
• Description:ES cell expressed Ras

DataSource: http://genomecrispr.dkfz.de/#!/results/ERAS

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48829216	48829239	X	-	26472758	Jiyoye	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	0.15745532895296033	[301]	[253]	1	hSpCas9	negative selection	51305
48829422	48829445	X	-	26472758	Jiyoye	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.23842092377149848	[307]	[273]	1	hSpCas9	negative selection	51306
48829306	48829329	X	+	26472758	Jiyoye	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.04550110782575456	[229]	[178]	0	hSpCas9	negative selection	51307
48829495	48829518	X	-	26472758	Jiyoye	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.8345966052405498	[28]	[38]	6	hSpCas9	negative selection	51308
48829593	48829616	X	-	26472758	Jiyoye	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	3.243676649222994	[13]	[99]	9	hSpCas9	negative selection	51309
48829622	48829645	X	+	26472758	Jiyoye	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	1.365220065064495	[156]	[304]	7	hSpCas9	negative selection	51310
48829661	48829684	X	+	26472758	Jiyoye	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	1.1493776240382267	[54]	[91]	7	hSpCas9	negative selection	51311
48829237	48829260	X	+	26472758	Jiyoye	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.12338241550528206	[55]	[45]	0	hSpCas9	negative selection	51312
48829361	48829384	X	+	26472758	Jiyoye	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.5639008851933266	[182]	[203]	4	hSpCas9	negative selection	51313
48829399	48829422	X	+	26472758	Jiyoye	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	0.4483980442323865	[68]	[70]	3	hSpCas9	negative selection	51314
48829216	48829239	X	-	26472758	KBM7	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	0.1644224434533601	[1406,1037]	[818,474]	1	hSpCas9	negative selection	242423
48829422	48829445	X	-	26472758	KBM7	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.7805528605667678	[1668,1709]	[1874,923]	8	hSpCas9	negative selection	242424
48829306	48829329	X	+	26472758	KBM7	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.3097205691741439	[894,904]	[397,642]	3	hSpCas9	negative selection	242425
48829495	48829518	X	-	26472758	KBM7	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	-0.1744770488443137	[221,96]	[61,65]	-2	hSpCas9	negative selection	242426
48829593	48829616	X	-	26472758	KBM7	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	-0.09124553001748659	[397,336]	[149,171]	-1	hSpCas9	negative selection	242427
48829622	48829645	X	+	26472758	KBM7	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.9402166790366373	[1203,1052]	[332,224]	-6	hSpCas9	negative selection	242428
48829661	48829684	X	+	26472758	KBM7	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	1.2984752527556767	[508,436]	[659,442]	9	hSpCas9	negative selection	242429
48829237	48829260	X	+	26472758	KBM7	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.07773449641942115	[337,322]	[165,162]	0	hSpCas9	negative selection	242430
48829361	48829384	X	+	26472758	KBM7	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.383563965595731	[754,724]	[517,398]	4	hSpCas9	negative selection	242431
48829399	48829422	X	+	26472758	KBM7	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	0.12754089797697643	[316,336]	[172,165]	1	hSpCas9	negative selection	242432
48829216	48829239	X	-	26472758	Raji	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	0.08046223605831071	[594]	[145]	0	hSpCas9	negative selection	433541
48829422	48829445	X	-	26472758	Raji	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.20503209938024836	[713]	[190]	2	hSpCas9	negative selection	433542
48829306	48829329	X	+	26472758	Raji	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.2553846982611532	[360]	[99]	2	hSpCas9	negative selection	433543
48829495	48829518	X	-	26472758	Raji	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.13775718441711837	[93]	[23]	1	hSpCas9	negative selection	433544
48829593	48829616	X	-	26472758	Raji	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	1.3132442328201592	[162]	[93]	9	hSpCas9	negative selection	433545
48829622	48829645	X	+	26472758	Raji	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	0.12535008190304842	[398]	[100]	1	hSpCas9	negative selection	433546
48829661	48829684	X	+	26472758	Raji	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	-0.18653018334416627	[254]	[51]	-1	hSpCas9	negative selection	433547
48829237	48829260	X	+	26472758	Raji	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.21121934635813955	[133]	[35]	2	hSpCas9	negative selection	433548
48829361	48829384	X	+	26472758	Raji	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	-0.459561130288795	[556]	[93]	-4	hSpCas9	negative selection	433549
48829399	48829422	X	+	26472758	Raji	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.01814734671025936	[191]	[43]	0	hSpCas9	negative selection	433550
48829216	48829239	X	-	26472758	K562	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.5247833714319772	[708]	[415]	-3	hSpCas9	negative selection	624659
48829422	48829445	X	-	26472758	K562	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	-0.17804972750331016	[1102]	[822]	-1	hSpCas9	negative selection	624660
48829306	48829329	X	+	26472758	K562	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	-1.5190446686768353	[695]	[204]	-6	hSpCas9	negative selection	624661
48829495	48829518	X	-	26472758	K562	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	1.1448830541155324	[119]	[223]	8	hSpCas9	negative selection	624662
48829593	48829616	X	-	26472758	K562	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.0804429925553209	[362]	[323]	0	hSpCas9	negative selection	624663
48829622	48829645	X	+	26472758	K562	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-2.1717893153203347	[821]	[153]	-7	hSpCas9	negative selection	624664
48829661	48829684	X	+	26472758	K562	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.9675003676966504	[354]	[585]	7	hSpCas9	negative selection	624665
48829237	48829260	X	+	26472758	K562	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	1.816181730632744	[182]	[543]	9	hSpCas9	negative selection	624666
48829361	48829384	X	+	26472758	K562	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	-0.5737884724388218	[833]	[472]	-4	hSpCas9	negative selection	624667
48829399	48829422	X	+	26472758	K562	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.1050951988928149	[329]	[258]	0	hSpCas9	negative selection	624668
48829300	48829323	X	-	26627737	DLD1	viability	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.2385191779659444	[490]	[53,318,176]	2	hSpCas9	negative selection	845838
48829354	48829377	X	+	26627737	DLD1	viability	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.2155270342845984	[710]	[120,296,164]	-2	hSpCas9	negative selection	845839
48829435	48829458	X	-	26627737	DLD1	viability	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	0.2350451938135466	[865]	[325,470,185]	2	hSpCas9	negative selection	845840
48829444	48829467	X	-	26627737	DLD1	viability	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.4473325640096183	[871]	[584,403,159]	4	hSpCas9	negative selection	845841
48829701	48829724	X	-	26627737	DLD1	viability	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.6776585309281176	[0]	[0,0,0]	9	hSpCas9	negative selection	845842
48829300	48829323	X	-	26627737	GBM cells	viability after 5 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.24607926127207091	[135]	[91,80]	4	hSpCas9	negative selection	928153
48829354	48829377	X	+	26627737	GBM cells	viability after 5 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	0.6844863744852077	[285]	[298,193]	8	hSpCas9	negative selection	928154
48829435	48829458	X	-	26627737	GBM cells	viability after 5 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.5197992825365567	[392]	[163,129]	-7	hSpCas9	negative selection	928155
48829444	48829467	X	-	26627737	GBM cells	viability after 5 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.4654612657803396	[456]	[198,155]	-6	hSpCas9	negative selection	928156
48829701	48829724	X	-	26627737	GBM cells	viability after 5 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.8989138748856851	[0]	[0,0]	9	hSpCas9	negative selection	928157
48829300	48829323	X	-	26627737	GBM cells	viability after 13 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.487922238755559	[135]	[108,98]	6	hSpCas9	negative selection	1010468
48829354	48829377	X	+	26627737	GBM cells	viability after 13 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	0.2349722496035564	[285]	[191,174]	3	hSpCas9	negative selection	1010469
48829435	48829458	X	-	26627737	GBM cells	viability after 13 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	0.08984546374285318	[392]	[232,221]	1	hSpCas9	negative selection	1010470
48829444	48829467	X	-	26627737	GBM cells	viability after 13 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.3630850313642824	[456]	[178,203]	-4	hSpCas9	negative selection	1010471
48829701	48829724	X	-	26627737	GBM cells	viability after 13 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.8821031235784469	[0]	[0,0]	9	hSpCas9	negative selection	1010472
48829300	48829323	X	-	26627737	GBM cells	viability after 21 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.464724254315003	[135]	[90,111]	5	hSpCas9	negative selection	1092783
48829354	48829377	X	+	26627737	GBM cells	viability after 21 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.353638618606508	[285]	[130,112]	-3	hSpCas9	negative selection	1092784
48829435	48829458	X	-	26627737	GBM cells	viability after 21 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.13823936045582041	[392]	[193,193]	-1	hSpCas9	negative selection	1092785
48829444	48829467	X	-	26627737	GBM cells	viability after 21 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.9086325398946792	[456]	[137,126]	-7	hSpCas9	negative selection	1092786
48829701	48829724	X	-	26627737	GBM cells	viability after 21 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.8802332996156581	[0]	[0,0]	8	hSpCas9	negative selection	1092787
48829300	48829323	X	-	26627737	RPE1	viability after 9 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.8020730799291174	[571]	[110,91]	-5	hSpCas9	negative selection	1175098
48829354	48829377	X	+	26627737	RPE1	viability after 9 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	1.6719457233790984	[307]	[308,304]	8	hSpCas9	negative selection	1175099
48829435	48829458	X	-	26627737	RPE1	viability after 9 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	2.0942668308263315	[400]	[446,650]	9	hSpCas9	negative selection	1175100
48829444	48829467	X	-	26627737	RPE1	viability after 9 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.1326845870838954	[1269]	[380,338]	-1	hSpCas9	negative selection	1175101
48829701	48829724	X	-	26627737	RPE1	viability after 9 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1175102
48829300	48829323	X	-	26627737	RPE1	viability after 12 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.6822365083508666	[571]	[121,67]	-5	hSpCas9	negative selection	1257413
48829354	48829377	X	+	26627737	RPE1	viability after 12 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	1.4984559906225303	[307]	[260,204]	8	hSpCas9	negative selection	1257414
48829435	48829458	X	-	26627737	RPE1	viability after 12 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	2.476784514452768	[400]	[470,735]	9	hSpCas9	negative selection	1257415
48829444	48829467	X	-	26627737	RPE1	viability after 12 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.16210625701245995	[1269]	[421,180]	-1	hSpCas9	negative selection	1257416
48829701	48829724	X	-	26627737	RPE1	viability after 12 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1257417
48829300	48829323	X	-	26627737	RPE1	viability after 15 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.5873510692152581	[571]	[124,90]	-4	hSpCas9	negative selection	1339728
48829354	48829377	X	+	26627737	RPE1	viability after 15 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	1.12327099963482	[307]	[144,232]	6	hSpCas9	negative selection	1339729
48829435	48829458	X	-	26627737	RPE1	viability after 15 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	2.023975041353276	[400]	[610,316]	8	hSpCas9	negative selection	1339730
48829444	48829467	X	-	26627737	RPE1	viability after 15 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.08578438767781682	[1269]	[421,257]	0	hSpCas9	negative selection	1339731
48829701	48829724	X	-	26627737	RPE1	viability after 15 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1339732
48829300	48829323	X	-	26627737	RPE1	viability after 18 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-1.3713116027784533	[571]	[49,69]	-7	hSpCas9	negative selection	1422043
48829354	48829377	X	+	26627737	RPE1	viability after 18 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	1.0054801374491495	[307]	[133,201]	6	hSpCas9	negative selection	1422044
48829435	48829458	X	-	26627737	RPE1	viability after 18 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	1.9108091972738233	[400]	[491,315]	8	hSpCas9	negative selection	1422045
48829444	48829467	X	-	26627737	RPE1	viability after 18 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.16302051107125337	[1269]	[579,173]	1	hSpCas9	negative selection	1422046
48829701	48829724	X	-	26627737	RPE1	viability after 18 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1422047
48829300	48829323	X	-	26627737	HeLa	viability after 8 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.16349366912214575	[267]	[195,105,105]	1	hSpCas9	negative selection	1504358
48829354	48829377	X	+	26627737	HeLa	viability after 8 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.02807995432120136	[580]	[303,275,180]	0	hSpCas9	negative selection	1504359
48829435	48829458	X	-	26627737	HeLa	viability after 8 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	1.5836078978120596	[211]	[519,233,138]	9	hSpCas9	negative selection	1504360
48829444	48829467	X	-	26627737	HeLa	viability after 8 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.5532019626120805	[605]	[279,451,403]	5	hSpCas9	negative selection	1504361
48829701	48829724	X	-	26627737	HeLa	viability after 8 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.200473099817617	[0]	[0,0,0]	8	hSpCas9	negative selection	1504362
48829300	48829323	X	-	26627737	HeLa	viability after 12 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.8191178992358794	[267]	[20,110,49]	-6	hSpCas9	negative selection	1586673
48829354	48829377	X	+	26627737	HeLa	viability after 12 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.06698316961829753	[580]	[147,212,325]	0	hSpCas9	negative selection	1586674
48829435	48829458	X	-	26627737	HeLa	viability after 12 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	1.9742273763467115	[211]	[552,247,247]	9	hSpCas9	negative selection	1586675
48829444	48829467	X	-	26627737	HeLa	viability after 12 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.12298457888916103	[605]	[367,375,65]	1	hSpCas9	negative selection	1586676
48829701	48829724	X	-	26627737	HeLa	viability after 12 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.2748581272013126	[0]	[0,0,0]	8	hSpCas9	negative selection	1586677
48829300	48829323	X	-	26627737	HeLa	viability after 15 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.552989516532344	[267]	[129,245,99]	4	hSpCas9	negative selection	1668988
48829354	48829377	X	+	26627737	HeLa	viability after 15 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.5208713821192211	[580]	[107,104,291]	-4	hSpCas9	negative selection	1668989
48829435	48829458	X	-	26627737	HeLa	viability after 15 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	2.230015725189576	[211]	[272,204,765]	9	hSpCas9	negative selection	1668990
48829444	48829467	X	-	26627737	HeLa	viability after 15 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.7202338560038819	[605]	[143,752,318]	5	hSpCas9	negative selection	1668991
48829701	48829724	X	-	26627737	HeLa	viability after 15 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.2965331123080048	[0]	[0,0,0]	8	hSpCas9	negative selection	1668992
48829300	48829323	X	-	26627737	HeLa	viability after 18 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.5287800170727955	[267]	[84,199,99]	4	hSpCas9	negative selection	1751303
48829354	48829377	X	+	26627737	HeLa	viability after 18 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.5741169490460005	[580]	[63,82,291]	-5	hSpCas9	negative selection	1751304
48829435	48829458	X	-	26627737	HeLa	viability after 18 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	2.210150386143484	[211]	[180,158,765]	9	hSpCas9	negative selection	1751305
48829444	48829467	X	-	26627737	HeLa	viability after 18 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.7198288561053359	[605]	[95,623,318]	5	hSpCas9	negative selection	1751306
48829701	48829724	X	-	26627737	HeLa	viability after 18 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.6067387639618715	[0]	[0,0,0]	9	hSpCas9	negative selection	1751307
48829300	48829323	X	-	26627737	HCT116	viability after 6 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	3.3368959340645783	[11]	[49,1]	9	hSpCas9	negative selection	1833618
48829354	48829377	X	+	26627737	HCT116	viability after 6 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.3242182350952491	[998]	[147,112]	-2	hSpCas9	negative selection	1833619
48829435	48829458	X	-	26627737	HCT116	viability after 6 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	0.2786357024853756	[992]	[267,145]	1	hSpCas9	negative selection	1833620
48829444	48829467	X	-	26627737	HCT116	viability after 6 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.09466246093051975	[779]	[41,154]	0	hSpCas9	negative selection	1833621
48829701	48829724	X	-	26627737	HCT116	viability after 6 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1833622
48829300	48829323	X	-	26627737	HCT116	viability after 8 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.49879470478601307	[197]	[93,65,71]	-5	hSpCas9	negative selection	1915933
48829354	48829377	X	+	26627737	HCT116	viability after 8 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	0.9703089484414529	[187]	[215,96,294]	8	hSpCas9	negative selection	1915934
48829435	48829458	X	-	26627737	HCT116	viability after 8 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	0.17053181417959182	[321]	[202,184,210]	2	hSpCas9	negative selection	1915935
48829444	48829467	X	-	26627737	HCT116	viability after 8 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.27547206533325386	[508]	[171,364,157]	-3	hSpCas9	negative selection	1915936
48829701	48829724	X	-	26627737	HCT116	viability after 8 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.8598070938499998	[0]	[0,0,0]	7	hSpCas9	negative selection	1915937
48829300	48829323	X	-	26627737	HCT116	viability after 9 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	4.235772136065121	[11]	[94,32]	9	hSpCas9	negative selection	1998248
48829354	48829377	X	+	26627737	HCT116	viability after 9 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.3672461111893274	[998]	[160,242]	-3	hSpCas9	negative selection	1998249
48829435	48829458	X	-	26627737	HCT116	viability after 9 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	1.607310080767223	[992]	[522,1032]	8	hSpCas9	negative selection	1998250
48829444	48829467	X	-	26627737	HCT116	viability after 9 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	1.4403185449809168	[779]	[214,841]	8	hSpCas9	negative selection	1998251
48829701	48829724	X	-	26627737	HCT116	viability after 9 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1998252
48829300	48829323	X	-	26627737	HCT116	viability after 12 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.48890074020793556	[197]	[116,119,202]	5	hSpCas9	negative selection	2080563
48829354	48829377	X	+	26627737	HCT116	viability after 12 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	1.4948873026527092	[187]	[271,280,282]	9	hSpCas9	negative selection	2080564
48829435	48829458	X	-	26627737	HCT116	viability after 12 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	0.4720268323923492	[321]	[315,192,186]	4	hSpCas9	negative selection	2080565
48829444	48829467	X	-	26627737	HCT116	viability after 12 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.05779030758620096	[508]	[271,284,278]	0	hSpCas9	negative selection	2080566
48829701	48829724	X	-	26627737	HCT116	viability after 12 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.9281650954308303	[0]	[0,0,0]	7	hSpCas9	negative selection	2080567
48829300	48829323	X	-	26627737	HCT116	viability after 15 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.5139683587769284	[197]	[53,120,60]	-5	hSpCas9	negative selection	2162878
48829354	48829377	X	+	26627737	HCT116	viability after 15 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	1.3112829877401144	[187]	[239,258,300]	8	hSpCas9	negative selection	2162879
48829435	48829458	X	-	26627737	HCT116	viability after 15 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	0.2302997533563799	[321]	[178,235,230]	2	hSpCas9	negative selection	2162880
48829444	48829467	X	-	26627737	HCT116	viability after 15 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.14742132004252995	[508]	[345,386,241]	1	hSpCas9	negative selection	2162881
48829701	48829724	X	-	26627737	HCT116	viability after 15 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.8001368291432343	[0]	[0,0,0]	7	hSpCas9	negative selection	2162882
48829300	48829323	X	-	26627737	HCT116	viability after 18 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.6096889045499283	[197]	[77,209,145]	5	hSpCas9	negative selection	2245193
48829354	48829377	X	+	26627737	HCT116	viability after 18 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	1.5922521079998697	[187]	[231,283,306]	9	hSpCas9	negative selection	2245194
48829435	48829458	X	-	26627737	HCT116	viability after 18 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	0.9165189330180906	[321]	[137,464,265]	7	hSpCas9	negative selection	2245195
48829444	48829467	X	-	26627737	HCT116	viability after 18 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.7678091133497182	[508]	[396,384,479]	6	hSpCas9	negative selection	2245196
48829701	48829724	X	-	26627737	HCT116	viability after 18 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2245197
48829371	48829394	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGCAGTCCCCACTGTCCAGGG	ERAS	ENSG00000187682	0.1859659206850821	[3,3]	[3,3]	4	hSpCas9	positive selection	2986199
48829202	48829225	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGGGCTCAGGCACGCCGCAGGG	ERAS	ENSG00000187682	-0.3948210915563826	[3,3]	[2,1]	-5	hSpCas9	positive selection	2986200
48829216	48829239	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.20253839623599146	[1,2]	[3,0]	-3	hSpCas9	positive selection	2986201
48829396	48829419	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAATGTGCTGGACACAGCAGGG	ERAS	ENSG00000187682	0.46703438197474906	[3,3]	[3,4]	8	hSpCas9	positive selection	2986202
48829371	48829394	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGCAGTCCCCACTGTCCAGGG	ERAS	ENSG00000187682	0.17440632124139074	[3,3]	[4,2]	3	hSpCas9	positive selection	3054057
48829202	48829225	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGGGCTCAGGCACGCCGCAGGG	ERAS	ENSG00000187682	0.6002412395741487	[3,3]	[3,3]	8	hSpCas9	positive selection	3054058
48829216	48829239	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	0.9153300505720625	[1,1]	[3,2]	9	hSpCas9	positive selection	3054059
48829396	48829419	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAATGTGCTGGACACAGCAGGG	ERAS	ENSG00000187682	0.2039164856290198	[3,3]	[2,2]	3	hSpCas9	positive selection	3054060
48829186	48829209		-	24336571	A375	resistance to PLX after 7 days	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.23638094624225747	[7,6]	[5,5]	-7	hSpCas9	positive selection	3112369
48829764	48829787		-	24336571	A375	resistance to PLX after 7 days	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.19848695189568888	[10,8]	[7,8]	-6	hSpCas9	positive selection	3112371
48829186	48829209		-	24336571	A375	resistance to PLX after 14 days	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.07174916216383788	[10,10]	[4,5]	0	hSpCas9	positive selection	3170162
48829764	48829787		-	24336571	A375	resistance to PLX after 14 days	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.49086657344561213	[8,6]	[2,1]	-6	hSpCas9	positive selection	3170164
48829186	48829209		-	24336571	A375	viability after 7 days	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.061599124185863	[7]	[7,6]	-1	hSpCas9	negative selection	3227955
48829764	48829787		-	24336571	A375	viability after 7 days	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.07118078395078353	[10]	[10,8]	-1	hSpCas9	negative selection	3227957
48829186	48829209		-	24336571	A375	viability after 14 days	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.49354793556354004	[7]	[10,10]	6	hSpCas9	negative selection	3285748
48829764	48829787		-	24336571	A375	viability after 14 days	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.33904581500336195	[10]	[8,6]	-4	hSpCas9	negative selection	3285750
48829186	48829209	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	3.3990201019414754	[14,13]	[0,0]	9	hSpCas9	positive selection	3348239
48829303	48829326	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	-0.2693072702356909	[167,200]	[0,0]	-2	hSpCas9	positive selection	3348240
48829312	48829335	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	-0.26269538690592903	[190,175]	[0,0]	-1	hSpCas9	positive selection	3348241
48829269	48829292	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	-2.4274224089757905	[822,822]	[0,0]	-9	hSpCas9	positive selection	3367450
48829764	48829787	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.46291034509572904	[110,110]	[0,0]	2	hSpCas9	positive selection	3367451
48829668	48829691	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	-0.7650416015826192	[259,259]	[0,0]	-5	hSpCas9	positive selection	3367452
48829371	48829394	X	-	26780180	HT29	viability (Avana library 4 designs)	AATGCAGTCCCCACTGTCCAGGG	ERAS	ENSG00000187682	1.00849323929677	[]	[]	4	hSpCas9	negative selection	3423022
48829201	48829224	X	+	26780180	HT29	viability (Avana library 4 designs)	CCGGGCTCAGGCACGCCGCAGGG	ERAS	ENSG00000187682	-0.499322748122479	[]	[]	-7	hSpCas9	negative selection	3423023
48829216	48829239	X	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	1.73857876754956	[]	[]	6	hSpCas9	negative selection	3423024
48829395	48829418	X	+	26780180	HT29	viability (Avana library 4 designs)	TGAATGTGCTGGACACAGCAGGG	ERAS	ENSG00000187682	2.50633211483455	[]	[]	8	hSpCas9	negative selection	3423025
48829395	48829418	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAATGTGCTGGACACAGCAGGG	ERAS	ENSG00000187682	1.70320785524408	[]	[]	2	hSpCas9	negative selection	3503971
48829216	48829239	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	2.87193986777446	[]	[]	4	hSpCas9	negative selection	3503972
48829201	48829224	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCGGGCTCAGGCACGCCGCAGGG	ERAS	ENSG00000187682	8.63183412959805	[]	[]	9	hSpCas9	negative selection	3503973
48829371	48829394	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGCAGTCCCCACTGTCCAGGG	ERAS	ENSG00000187682	5.01381120286993	[]	[]	8	hSpCas9	negative selection	3503974
48829186	48829209	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	4.82500139941872	[]	[]	8	hSpCas9	negative selection	3503975
48829341	48829364	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCCAGTAGGAATCCTGGATGG	ERAS	ENSG00000187682	3.23792026726161	[]	[]	5	hSpCas9	negative selection	3503976
48829395	48829418	X	+	26780180	A375	viability (Avana lentiGuide)	TGAATGTGCTGGACACAGCAGGG	ERAS	ENSG00000187682	1.08528822754929	[]	[]	1	hSpCas9	negative selection	3612630
48829216	48829239	X	-	26780180	A375	viability (Avana lentiGuide)	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	2.57088254940979	[]	[]	2	hSpCas9	negative selection	3612631
48829201	48829224	X	+	26780180	A375	viability (Avana lentiGuide)	CCGGGCTCAGGCACGCCGCAGGG	ERAS	ENSG00000187682	-1.52882848019611	[]	[]	-2	hSpCas9	negative selection	3612632
48829371	48829394	X	-	26780180	A375	viability (Avana lentiGuide)	AATGCAGTCCCCACTGTCCAGGG	ERAS	ENSG00000187682	-2.51276089536352	[]	[]	-4	hSpCas9	negative selection	3612633
48829186	48829209	X	-	26780180	A375	viability (Avana lentiGuide)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-3.1394651952738	[]	[]	-5	hSpCas9	negative selection	3612634
48829341	48829364	X	-	26780180	A375	viability (Avana lentiGuide)	CTTCCAGTAGGAATCCTGGATGG	ERAS	ENSG00000187682	1.63217458584815	[]	[]	1	hSpCas9	negative selection	3612635
48829395	48829418	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAATGTGCTGGACACAGCAGGG	ERAS	ENSG00000187682	0.07152869554418523	[5]	[6,4]	1	hSpCas9	positive selection	3721289
48829216	48829239	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	0.047851985701315256	[4]	[5,3]	1	hSpCas9	positive selection	3721290
48829201	48829224	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGGGCTCAGGCACGCCGCAGGG	ERAS	ENSG00000187682	0.3318736143369061	[4]	[5,5]	8	hSpCas9	positive selection	3721291
48829371	48829394	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGCAGTCCCCACTGTCCAGGG	ERAS	ENSG00000187682	0.29131967891319693	[5]	[6,6]	8	hSpCas9	positive selection	3721292
48829186	48829209	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.3658275998205324	[5]	[7,7]	9	hSpCas9	positive selection	3721293
48829341	48829364	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCCAGTAGGAATCCTGGATGG	ERAS	ENSG00000187682	0.14558405920237333	[6]	[7,6]	4	hSpCas9	positive selection	3721294
48829395	48829418	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAATGTGCTGGACACAGCAGGG	ERAS	ENSG00000187682	-0.007948562412167817	[5]	[2,5]	0	hSpCas9	positive selection	3829896
48829216	48829239	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.4376855539368819	[4]	[3,2]	-5	hSpCas9	positive selection	3829897
48829201	48829224	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGGGCTCAGGCACGCCGCAGGG	ERAS	ENSG00000187682	-0.3661520082785363	[5]	[2,3]	-5	hSpCas9	positive selection	3829898
48829371	48829394	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGCAGTCCCCACTGTCCAGGG	ERAS	ENSG00000187682	0.15273133600415376	[5]	[4,5]	3	hSpCas9	positive selection	3829899
48829186	48829209	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.33721123933966823	[6]	[6,7]	8	hSpCas9	positive selection	3829900
48829341	48829364	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCCAGTAGGAATCCTGGATGG	ERAS	ENSG00000187682	0.0992080461265277	[6]	[5,5]	2	hSpCas9	positive selection	3829901
48829269	48829292	X	-	26780180	A375	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	1.07639304876214	[]	[]	5	hSpCas9	negative selection	3937251
48829312	48829335	X	-	26780180	A375	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.657459851929836	[]	[]	2	hSpCas9	negative selection	3937252
48829668	48829691	X	-	26780180	A375	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.346665542242666	[]	[]	0	hSpCas9	negative selection	3937253
48829186	48829209	X	-	26780180	A375	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.28651806400879	[]	[]	0	hSpCas9	negative selection	3937254
48829303	48829326	X	+	26780180	A375	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.747792740546837	[]	[]	2	hSpCas9	negative selection	3937255
48829764	48829787	X	-	26780180	A375	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	1.36766500176774	[]	[]	7	hSpCas9	negative selection	3937256
48829269	48829292	X	-	26780180	HT29	viability (GeCKOv2 library)	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.990544396467498	[]	[]	4	hSpCas9	negative selection	4045217
48829312	48829335	X	-	26780180	HT29	viability (GeCKOv2 library)	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	1.21647523784414	[]	[]	6	hSpCas9	negative selection	4045218
48829668	48829691	X	-	26780180	HT29	viability (GeCKOv2 library)	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.227681822346702	[]	[]	0	hSpCas9	negative selection	4045219
48829186	48829209	X	-	26780180	HT29	viability (GeCKOv2 library)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	1.28061768039189	[]	[]	6	hSpCas9	negative selection	4045220
48829303	48829326	X	+	26780180	HT29	viability (GeCKOv2 library)	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	-0.156766310984163	[]	[]	-4	hSpCas9	negative selection	4045221
48829764	48829787	X	-	26780180	HT29	viability (GeCKOv2 library)	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	1.86288345093406	[]	[]	8	hSpCas9	negative selection	4045222
48829186	48829209	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.09482472268160168	[3]	[1,2]	2	hSpCas9	positive selection	4135094
48829764	48829787	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.2367790714584917	[3]	[2,0]	-5	hSpCas9	positive selection	4135096
48829186	48829209	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	1.151079093647774	[2]	[2,0,2,3]	8	hSpCas9	positive selection	4199116
48829764	48829787	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.419789784103844	[3]	[0,0,0,2]	3	hSpCas9	positive selection	4199118
48829186	48829209	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.2519073941646448	[2]	[1,0]	-5	hSpCas9	positive selection	4269099
48829303	48829326	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.11134705552570154	[3]	[3,1]	2	hSpCas9	positive selection	4269100
48829312	48829335	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.4708644221047482	[3]	[3,4]	8	hSpCas9	positive selection	4269101
48829269	48829292	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.23316202932224117	[4]	[4,3]	5	hSpCas9	positive selection	4333364
48829764	48829787	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.30150830729138267	[2]	[2,0]	-6	hSpCas9	positive selection	4333365
48829668	48829691	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.30239213250340213	[3]	[3,2]	6	hSpCas9	positive selection	4333366
48829241	48829263	X	-	27760321	OCIAML3	viability	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.7101015975021979	[631,551]	[598,959]	8	hSpCas9	negative selection	4398168
48829312	48829334	X	-	27760321	OCIAML3	viability	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.42847099791059867	[647,444]	[474,689]	5	hSpCas9	negative selection	4398169
48829343	48829365	X	+	27760321	OCIAML3	viability	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.1408059301729383	[353,313]	[290,282]	1	hSpCas9	negative selection	4398170
48829363	48829385	X	+	27760321	OCIAML3	viability	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.24428275121317694	[737,686]	[355,619]	-3	hSpCas9	negative selection	4398171
48829412	48829434	X	+	27760321	OCIAML3	viability	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	1.0720585811059617	[331,298]	[509,528]	9	hSpCas9	negative selection	4398172
48829241	48829263	X	-	27760321	OCIAML2	viability	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.7484031552376474	[631,551]	[740,883]	8	hSpCas9	negative selection	4481631
48829312	48829334	X	-	27760321	OCIAML2	viability	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.6452129590030948	[647,444]	[680,685]	8	hSpCas9	negative selection	4481632
48829343	48829365	X	+	27760321	OCIAML2	viability	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	-0.26723090066786803	[353,313]	[161,305]	-3	hSpCas9	negative selection	4481633
48829363	48829385	X	+	27760321	OCIAML2	viability	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.06711297038036701	[737,686]	[536,567]	-1	hSpCas9	negative selection	4481634
48829412	48829434	X	+	27760321	OCIAML2	viability	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.4942216658887924	[331,298]	[296,440]	6	hSpCas9	negative selection	4481635
48829241	48829263	X	-	27760321	MV411	viability	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.8842423020103748	[631,551]	[778,629]	6	hSpCas9	negative selection	4565094
48829312	48829334	X	-	27760321	MV411	viability	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.7867665562867885	[647,444]	[768,382]	6	hSpCas9	negative selection	4565095
48829343	48829365	X	+	27760321	MV411	viability	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.5617641049348874	[353,313]	[331,313]	4	hSpCas9	negative selection	4565096
48829363	48829385	X	+	27760321	MV411	viability	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.980218155196294	[737,686]	[18,567]	-6	hSpCas9	negative selection	4565097
48829412	48829434	X	+	27760321	MV411	viability	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	-0.48376419733329534	[331,298]	[69,266]	-3	hSpCas9	negative selection	4565098
48829241	48829263	X	-	27760321	HL60	viability	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.67422756668952	[631,551]	[767,771]	7	hSpCas9	negative selection	4648557
48829312	48829334	X	-	27760321	HL60	viability	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	1.2084922639264526	[647,444]	[996,1042]	9	hSpCas9	negative selection	4648558
48829343	48829365	X	+	27760321	HL60	viability	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.21624471756926802	[353,313]	[330,300]	2	hSpCas9	negative selection	4648559
48829363	48829385	X	+	27760321	HL60	viability	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.8931828854635241	[737,686]	[312,313]	-7	hSpCas9	negative selection	4648560
48829412	48829434	X	+	27760321	HL60	viability	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	1.4617849512832595	[331,298]	[764,649]	9	hSpCas9	negative selection	4648561
48829241	48829263	X	-	27760321	HT1080	viability	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	1.4703079084278345	[551,430]	[595,483]	7	hSpCas9	negative selection	4732020
48829312	48829334	X	-	27760321	HT1080	viability	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.5386646547112187	[444,346]	[168,294]	3	hSpCas9	negative selection	4732021
48829343	48829365	X	+	27760321	HT1080	viability	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.22898468554689064	[313,244]	[161,95]	1	hSpCas9	negative selection	4732022
48829363	48829385	X	+	27760321	HT1080	viability	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.3433994094813376	[686,535]	[191,191]	-1	hSpCas9	negative selection	4732023
48829412	48829434	X	+	27760321	HT1080	viability	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.18440805202820937	[298,233]	[102,139]	0	hSpCas9	negative selection	4732024
48829241	48829263	X	-	27760321	HT29	viability after 7 days	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.8833821641893365	[551,430]	[1292,1350,878]	9	hSpCas9	negative selection	4815483
48829312	48829334	X	-	27760321	HT29	viability after 7 days	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.23840309965046833	[444,346]	[843,720,280]	3	hSpCas9	negative selection	4815484
48829343	48829365	X	+	27760321	HT29	viability after 7 days	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.22922958231849283	[313,244]	[557,220,500]	3	hSpCas9	negative selection	4815485
48829363	48829385	X	+	27760321	HT29	viability after 7 days	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.10247301659889108	[686,535]	[705,719,764]	-1	hSpCas9	negative selection	4815486
48829412	48829434	X	+	27760321	HT29	viability after 7 days	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.5886635658972637	[298,233]	[759,455,368]	8	hSpCas9	negative selection	4815487
48829241	48829263	X	-	27760321	HT29	viability after 25 days	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.7171488376917361	[551,430]	[830,1094,839]	7	hSpCas9	negative selection	4898946
48829312	48829334	X	-	27760321	HT29	viability after 25 days	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.4104057056588124	[444,346]	[635,608,550]	4	hSpCas9	negative selection	4898947
48829343	48829365	X	+	27760321	HT29	viability after 25 days	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.7071827458334956	[313,244]	[555,444,564]	7	hSpCas9	negative selection	4898948
48829363	48829385	X	+	27760321	HT29	viability after 25 days	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.727589246364798	[686,535]	[457,444,352]	-6	hSpCas9	negative selection	4898949
48829412	48829434	X	+	27760321	HT29	viability after 25 days	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	1.322440223696513	[298,233]	[570,896,835]	9	hSpCas9	negative selection	4898950
48829241	48829263	X	-	27760321	HT29	viability after 22 days	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.7290972071059223	[551,430]	[840,1076,909]	7	hSpCas9	negative selection	4982409
48829312	48829334	X	-	27760321	HT29	viability after 22 days	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	-0.04184629830550754	[444,346]	[452,415,464]	0	hSpCas9	negative selection	4982410
48829343	48829365	X	+	27760321	HT29	viability after 22 days	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	-0.0014250298120971339	[313,244]	[391,302,270]	0	hSpCas9	negative selection	4982411
48829363	48829385	X	+	27760321	HT29	viability after 22 days	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.5117973090014921	[686,535]	[512,465,507]	-5	hSpCas9	negative selection	4982412
48829412	48829434	X	+	27760321	HT29	viability after 22 days	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	1.0051232522349371	[298,233]	[439,614,806]	9	hSpCas9	negative selection	4982413
48829241	48829263	X	-	27760321	HT29	viability after 19 days	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.8463617461421749	[551,430]	[491,1471,1012]	8	hSpCas9	negative selection	5065872
48829312	48829334	X	-	27760321	HT29	viability after 19 days	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.3463483152538184	[444,346]	[508,557,649]	3	hSpCas9	negative selection	5065873
48829343	48829365	X	+	27760321	HT29	viability after 19 days	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	-0.32071786924748436	[313,244]	[574,129,101]	-3	hSpCas9	negative selection	5065874
48829363	48829385	X	+	27760321	HT29	viability after 19 days	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.7936705463955182	[686,535]	[510,459,255]	-6	hSpCas9	negative selection	5065875
48829412	48829434	X	+	27760321	HT29	viability after 19 days	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.9938530941862149	[298,233]	[590,535,688]	9	hSpCas9	negative selection	5065876
48829241	48829263	X	-	27760321	HT29	viability after 16 days	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.6965614566078278	[551,430]	[1105,804,784]	7	hSpCas9	negative selection	5149335
48829312	48829334	X	-	27760321	HT29	viability after 16 days	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.13121014935139627	[444,346]	[469,373,612]	1	hSpCas9	negative selection	5149336
48829343	48829365	X	+	27760321	HT29	viability after 16 days	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.38237841078162893	[313,244]	[544,281,411]	4	hSpCas9	negative selection	5149337
48829363	48829385	X	+	27760321	HT29	viability after 16 days	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-1.0073408826457873	[686,535]	[404,188,436]	-7	hSpCas9	negative selection	5149338
48829412	48829434	X	+	27760321	HT29	viability after 16 days	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.7730619887096225	[298,233]	[637,351,554]	8	hSpCas9	negative selection	5149339
48829241	48829263	X	-	27760321	HT29	viability after 13 days	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.5060941881250679	[551,430]	[944,691,792]	6	hSpCas9	negative selection	5232798
48829312	48829334	X	-	27760321	HT29	viability after 13 days	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	-0.15840730591298136	[444,346]	[292,529,411]	-2	hSpCas9	negative selection	5232799
48829343	48829365	X	+	27760321	HT29	viability after 13 days	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.3587074205463896	[313,244]	[424,470,354]	4	hSpCas9	negative selection	5232800
48829363	48829385	X	+	27760321	HT29	viability after 13 days	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.4798779809787515	[686,535]	[506,443,570]	-5	hSpCas9	negative selection	5232801
48829412	48829434	X	+	27760321	HT29	viability after 13 days	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.6219327915611554	[298,233]	[407,446,566]	7	hSpCas9	negative selection	5232802
48829241	48829263	X	-	27760321	HT29	viability after 10 days	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	0.6554460727810854	[551,430]	[504,858,1519]	8	hSpCas9	negative selection	5316261
48829312	48829334	X	-	27760321	HT29	viability after 10 days	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.3298974116142275	[444,346]	[943,613,312]	4	hSpCas9	negative selection	5316262
48829343	48829365	X	+	27760321	HT29	viability after 10 days	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	-0.5051779238807996	[313,244]	[241,195,296]	-6	hSpCas9	negative selection	5316263
48829363	48829385	X	+	27760321	HT29	viability after 10 days	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.4040541522228155	[686,535]	[384,745,603]	-5	hSpCas9	negative selection	5316264
48829412	48829434	X	+	27760321	HT29	viability after 10 days	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.8898543460113503	[298,233]	[667,755,433]	9	hSpCas9	negative selection	5316265
48829241	48829263	X	-	27760321	MOLM13	viability	CCACCACAGCCTTGTACTCAGG	ERAS	ENSG00000187682	3.1161959249409446	[631,551]	[5295,840]	9	hSpCas9	negative selection	5399724
48829312	48829334	X	-	27760321	MOLM13	viability	GTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	1.212223192799039	[647,444]	[1097,371]	8	hSpCas9	negative selection	5399725
48829343	48829365	X	+	27760321	MOLM13	viability	ATCCAGGATTCCTACTGGAAGG	ERAS	ENSG00000187682	0.9030608327035773	[353,313]	[434,280]	6	hSpCas9	negative selection	5399726
48829363	48829385	X	+	27760321	MOLM13	viability	GGAGTTGACCCTGGACAGTGGG	ERAS	ENSG00000187682	-0.6202116885104421	[737,686]	[481,73]	-4	hSpCas9	negative selection	5399727
48829412	48829434	X	+	27760321	MOLM13	viability	GCAGGGCAGGCCATCCATAGGG	ERAS	ENSG00000187682	0.027668580875003124	[331,298]	[291,86]	0	hSpCas9	negative selection	5399728
48829240	48829263	X	+	27661255	K562	viability	GCCTGAGTACAAGGCTGTGGTGG	ERAS	ENSG00000187682	0.17386574558410017	[144,225]	[140,186]	6	dCas9-KRAB	negative selection	5477685
48829070	48829093	X	-	27661255	K562	viability	GGGCAGCAGGCTCTGCAAGTGGG	ERAS	ENSG00000187682	0.12754697714068464	[1337,1523]	[1261,1231]	4	dCas9-KRAB	negative selection	5477686
48829090	48829113	X	-	27661255	K562	viability	GCAGCTCAGGGAAGAGACGTGGG	ERAS	ENSG00000187682	0.15889674529442244	[638,643]	[652,502]	5	dCas9-KRAB	negative selection	5477687
48829309	48829332	X	-	27661255	K562	viability	GGTCCTCCACGAAGCACTGGTGG	ERAS	ENSG00000187682	0.017494469858576167	[952,1052]	[849,774]	0	dCas9-KRAB	negative selection	5477688
48829186	48829209	X	-	27260156	BXPC3	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.23491049251001372	[236]	[205,336,319,310]	5	hSpCas9	negative selection	5541559
48829303	48829326	X	+	27260156	BXPC3	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.34011917522268764	[590]	[660,811,745,933]	7	hSpCas9	negative selection	5541560
48829312	48829335	X	-	27260156	BXPC3	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.33025872330284045	[659]	[699,867,817,1127]	7	hSpCas9	negative selection	5541561
48829269	48829292	X	-	27260156	BXPC3	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.2575184176355598	[1634]	[1857,1758,2109,2531]	5	hSpCas9	negative selection	5605824
48829764	48829787	X	-	27260156	BXPC3	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.3984763121603044	[283]	[410,405,317,427]	8	hSpCas9	negative selection	5605825
48829668	48829691	X	-	27260156	BXPC3	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.11087835981424343	[537]	[491,482,622,881]	2	hSpCas9	negative selection	5605826
48829186	48829209	X	-	27260156	A673	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.008639689437824782	[236]	[226,290,306,299]	0	hSpCas9	negative selection	5662810
48829303	48829326	X	+	27260156	A673	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.5270305781418758	[590]	[1179,975,1022,922]	9	hSpCas9	negative selection	5662811
48829312	48829335	X	-	27260156	A673	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.19582618590770784	[659]	[991,779,954,914]	4	hSpCas9	negative selection	5662812
48829269	48829292	X	-	27260156	A673	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.23184181942450288	[1634]	[2435,2006,2173,2642]	5	hSpCas9	negative selection	5727075
48829764	48829787	X	-	27260156	A673	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.25792810578415926	[283]	[484,444,317,389]	6	hSpCas9	negative selection	5727076
48829668	48829691	X	-	27260156	A673	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.07625345110956167	[537]	[968,597,537,652]	1	hSpCas9	negative selection	5727077
48829186	48829209	X	-	27260156	A375	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.048402447156873585	[236]	[241,200,365,252]	0	hSpCas9	negative selection	5784061
48829303	48829326	X	+	27260156	A375	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.8424425128165791	[590]	[1361,1411,1095,1115]	9	hSpCas9	negative selection	5784062
48829312	48829335	X	-	27260156	A375	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.37597753901572384	[659]	[845,1258,1033,904]	5	hSpCas9	negative selection	5784063
48829269	48829292	X	-	27260156	A375	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.34234059959771757	[1634]	[2736,2588,2243,2161]	5	hSpCas9	negative selection	5848326
48829764	48829787	X	-	27260156	A375	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.39584730370824917	[283]	[428,479,431,411]	6	hSpCas9	negative selection	5848327
48829668	48829691	X	-	27260156	A375	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.2872776976698389	[537]	[677,677,869,818]	4	hSpCas9	negative selection	5848328
48829186	48829209	X	-	27260156	COLO741	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.3449444187896673	[236]	[275,163,274]	-6	hSpCas9	negative selection	5905312
48829303	48829326	X	+	27260156	COLO741	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.3995350093863268	[590]	[1146,848,1001]	7	hSpCas9	negative selection	5905313
48829312	48829335	X	-	27260156	COLO741	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.22476641290011978	[659]	[1005,868,1073]	5	hSpCas9	negative selection	5905314
48829269	48829292	X	-	27260156	COLO741	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.2118116027272927	[1634]	[2429,2533,2298]	4	hSpCas9	negative selection	5969577
48829764	48829787	X	-	27260156	COLO741	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.009167836029077003	[283]	[211,517,352]	0	hSpCas9	negative selection	5969578
48829668	48829691	X	-	27260156	COLO741	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.05294216352725395	[537]	[811,719,620]	1	hSpCas9	negative selection	5969579
48829186	48829209	X	-	27260156	CAL120	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.5119188023419827	[236]	[490,357,422]	7	hSpCas9	negative selection	6026563
48829303	48829326	X	+	27260156	CAL120	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.7194760450327384	[590]	[1302,1120,1221]	9	hSpCas9	negative selection	6026564
48829312	48829335	X	-	27260156	CAL120	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.3166983409960813	[659]	[993,1273,799]	5	hSpCas9	negative selection	6026565
48829269	48829292	X	-	27260156	CAL120	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.25720946690915203	[1634]	[2693,2072,2563]	4	hSpCas9	negative selection	6090828
48829764	48829787	X	-	27260156	CAL120	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.8796036054673688	[283]	[715,521,720]	9	hSpCas9	negative selection	6090829
48829668	48829691	X	-	27260156	CAL120	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.20981934063778623	[537]	[825,600,900]	3	hSpCas9	negative selection	6090830
48829186	48829209	X	-	27260156	CADOES1	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.012286721911034859	[236]	[211,211,197,268]	0	hSpCas9	negative selection	6147814
48829303	48829326	X	+	27260156	CADOES1	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.4855765162354927	[590]	[581,873,779,845]	7	hSpCas9	negative selection	6147815
48829312	48829335	X	-	27260156	CADOES1	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.1590179294587719	[659]	[860,579,456,848]	2	hSpCas9	negative selection	6147816
48829269	48829292	X	-	27260156	CADOES1	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.09548286648230109	[1634]	[1817,1611,1450,1616]	1	hSpCas9	negative selection	6212079
48829764	48829787	X	-	27260156	CADOES1	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.31980537846882034	[283]	[351,310,265,391]	5	hSpCas9	negative selection	6212080
48829668	48829691	X	-	27260156	CADOES1	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.44534771234137227	[537]	[716,686,594,727]	7	hSpCas9	negative selection	6212081
48829186	48829209	X	-	27260156	EWS502	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.016495224725919355	[236]	[241,257,262,252]	0	hSpCas9	negative selection	6269065
48829303	48829326	X	+	27260156	EWS502	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.5211816987497517	[590]	[909,926,1006,732]	8	hSpCas9	negative selection	6269066
48829312	48829335	X	-	27260156	EWS502	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	-0.07198097154418193	[659]	[498,737,729,711]	-1	hSpCas9	negative selection	6269067
48829269	48829292	X	-	27260156	EWS502	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.3613950506214054	[1634]	[1822,2619,2485,1979]	6	hSpCas9	negative selection	6333330
48829764	48829787	X	-	27260156	EWS502	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.46066967783401636	[283]	[401,386,411,458]	7	hSpCas9	negative selection	6333331
48829668	48829691	X	-	27260156	EWS502	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.11497838380497571	[537]	[649,433,780,605]	2	hSpCas9	negative selection	6333332
48829186	48829209	X	-	27260156	EW8	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.10756401601958276	[236]	[243,153,194,123]	-2	hSpCas9	negative selection	6390316
48829303	48829326	X	+	27260156	EW8	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.4715632613747932	[590]	[492,716,679,742]	8	hSpCas9	negative selection	6390317
48829312	48829335	X	-	27260156	EW8	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	-0.02304491899019795	[659]	[577,554,430,561]	0	hSpCas9	negative selection	6390318
48829269	48829292	X	-	27260156	EW8	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.21377621395317203	[1634]	[1637,1552,1468,1504]	4	hSpCas9	negative selection	6454581
48829764	48829787	X	-	27260156	EW8	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.22216163255441523	[283]	[304,205,284,277]	4	hSpCas9	negative selection	6454582
48829668	48829691	X	-	27260156	EW8	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.19464334246286802	[537]	[530,510,391,581]	3	hSpCas9	negative selection	6454583
48829186	48829209	X	-	27260156	CORL105	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.15148690089932748	[236]	[235,372,321,299]	3	hSpCas9	negative selection	6511567
48829303	48829326	X	+	27260156	CORL105	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.5717249446927111	[590]	[861,977,1269,1035]	9	hSpCas9	negative selection	6511568
48829312	48829335	X	-	27260156	CORL105	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.1111262645955744	[659]	[828,696,973,861]	2	hSpCas9	negative selection	6511569
48829269	48829292	X	-	27260156	CORL105	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.32591925511571396	[1634]	[1884,2344,3048,2401]	6	hSpCas9	negative selection	6575832
48829764	48829787	X	-	27260156	CORL105	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.16857349954779233	[283]	[404,270,489,349]	3	hSpCas9	negative selection	6575833
48829668	48829691	X	-	27260156	CORL105	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.4227353421923946	[537]	[952,859,839,726]	7	hSpCas9	negative selection	6575834
48829186	48829209	X	-	27260156	HS294T	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.03651726542873268	[236]	[75,64,144,69]	0	hSpCas9	negative selection	6632818
48829303	48829326	X	+	27260156	HS294T	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.4658615690747837	[590]	[313,375,250,318]	6	hSpCas9	negative selection	6632819
48829312	48829335	X	-	27260156	HS294T	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.3991295968895021	[659]	[181,242,332,658]	5	hSpCas9	negative selection	6632820
48829269	48829292	X	-	27260156	HS294T	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.3622615590737237	[1634]	[734,702,933,901]	5	hSpCas9	negative selection	6697083
48829764	48829787	X	-	27260156	HS294T	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.4905743309274927	[283]	[55,77,89,92]	-6	hSpCas9	negative selection	6697084
48829668	48829691	X	-	27260156	HS294T	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.4952559116950125	[537]	[148,570,214,230]	6	hSpCas9	negative selection	6697085
48829186	48829209	X	-	27260156	HCC44	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.04584716432341174	[236]	[240,172,477,194]	0	hSpCas9	negative selection	6754069
48829303	48829326	X	+	27260156	HCC44	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.5774450155864971	[590]	[972,656,1349,1104]	8	hSpCas9	negative selection	6754070
48829312	48829335	X	-	27260156	HCC44	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.39182875716031984	[659]	[1104,874,1064,907]	6	hSpCas9	negative selection	6754071
48829269	48829292	X	-	27260156	HCC44	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.2707576337208477	[1634]	[2284,1863,2776,2133]	4	hSpCas9	negative selection	6818334
48829764	48829787	X	-	27260156	HCC44	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.1554568791947727	[283]	[550,269,358,280]	2	hSpCas9	negative selection	6818335
48829668	48829691	X	-	27260156	HCC44	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.31793389021158125	[537]	[792,584,911,790]	5	hSpCas9	negative selection	6818336
48829186	48829209	X	-	27260156	G402	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.5423112793883373	[236]	[442,486,191,560]	6	hSpCas9	negative selection	6875320
48829303	48829326	X	+	27260156	G402	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.8686170003674758	[590]	[1411,1601,1063,1218]	9	hSpCas9	negative selection	6875321
48829312	48829335	X	-	27260156	G402	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.10459549666215906	[659]	[450,647,985,1281]	1	hSpCas9	negative selection	6875322
48829269	48829292	X	-	27260156	G402	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.08362588220697331	[1634]	[2518,2033,2174,1789]	1	hSpCas9	negative selection	6939585
48829764	48829787	X	-	27260156	G402	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.27285355676737977	[283]	[454,235,72,397]	-3	hSpCas9	negative selection	6939586
48829668	48829691	X	-	27260156	G402	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.4350654853637045	[537]	[829,965,1157,602]	5	hSpCas9	negative selection	6939587
48829186	48829209	X	-	27260156	L33	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.13782760850588183	[236]	[232,80,144,199]	-3	hSpCas9	negative selection	6996571
48829303	48829326	X	+	27260156	L33	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.31665520359808275	[590]	[739,317,458,697]	6	hSpCas9	negative selection	6996572
48829312	48829335	X	-	27260156	L33	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.03347507366324787	[659]	[653,249,421,765]	0	hSpCas9	negative selection	6996573
48829269	48829292	X	-	27260156	L33	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.3489652445838629	[1634]	[1934,893,1375,2027]	7	hSpCas9	negative selection	7060836
48829764	48829787	X	-	27260156	L33	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.1665136924169942	[283]	[301,135,180,352]	3	hSpCas9	negative selection	7060837
48829668	48829691	X	-	27260156	L33	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.042563054746712015	[537]	[537,232,448,397]	1	hSpCas9	negative selection	7060838
48829186	48829209	X	-	27260156	K562	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.7721989551016455	[236]	[261,343,597,236]	8	hSpCas9	negative selection	7117822
48829303	48829326	X	+	27260156	K562	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.7436966861380041	[590]	[841,949,972,758]	8	hSpCas9	negative selection	7117823
48829312	48829335	X	-	27260156	K562	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.5646705011071725	[659]	[689,442,1040,1209]	7	hSpCas9	negative selection	7117824
48829269	48829292	X	-	27260156	K562	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.36072584867644486	[1634]	[2074,2435,1891,1170]	4	hSpCas9	negative selection	7182087
48829764	48829787	X	-	27260156	K562	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.14977984889591556	[283]	[198,356,300,259]	1	hSpCas9	negative selection	7182088
48829668	48829691	X	-	27260156	K562	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	-0.1949015103254713	[537]	[482,393,170,600]	-2	hSpCas9	negative selection	7182089
48829186	48829209	X	-	27260156	HT29	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.042593469689252705	[236]	[313,269,277,318]	0	hSpCas9	negative selection	7239073
48829303	48829326	X	+	27260156	HT29	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.5376135242333746	[590]	[1144,1213,1032,821]	9	hSpCas9	negative selection	7239074
48829312	48829335	X	-	27260156	HT29	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.11241927501769222	[659]	[879,900,873,817]	2	hSpCas9	negative selection	7239075
48829269	48829292	X	-	27260156	HT29	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.055661723732103985	[1634]	[2257,2165,2219,1675]	1	hSpCas9	negative selection	7303338
48829764	48829787	X	-	27260156	HT29	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.19747796381267457	[283]	[495,426,370,307]	4	hSpCas9	negative selection	7303339
48829668	48829691	X	-	27260156	HT29	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.38072268511990504	[537]	[937,1201,610,703]	7	hSpCas9	negative selection	7303340
48829186	48829209	X	-	27260156	MHHES1	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.1263612178099991	[236]	[248,271,405,237]	2	hSpCas9	negative selection	7360324
48829303	48829326	X	+	27260156	MHHES1	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.4024773438670892	[590]	[1128,886,728,801]	7	hSpCas9	negative selection	7360325
48829312	48829335	X	-	27260156	MHHES1	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.31675740892017346	[659]	[1132,1149,862,648]	6	hSpCas9	negative selection	7360326
48829269	48829292	X	-	27260156	MHHES1	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.28360683575611145	[1634]	[2295,2859,2089,1832]	5	hSpCas9	negative selection	7424589
48829764	48829787	X	-	27260156	MHHES1	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.32494753957683375	[283]	[333,334,487,417]	6	hSpCas9	negative selection	7424590
48829668	48829691	X	-	27260156	MHHES1	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.15396796532461976	[537]	[1072,536,562,566]	3	hSpCas9	negative selection	7424591
48829186	48829209	X	-	27260156	MEWO	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.019255938177475507	[236]	[295,200,190]	0	hSpCas9	negative selection	7481575
48829303	48829326	X	+	27260156	MEWO	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.3743401827727719	[590]	[667,829,641]	7	hSpCas9	negative selection	7481576
48829312	48829335	X	-	27260156	MEWO	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.04887613415279857	[659]	[806,576,564]	1	hSpCas9	negative selection	7481577
48829269	48829292	X	-	27260156	MEWO	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.26377569704040194	[1634]	[2157,1717,1695]	6	hSpCas9	negative selection	7545840
48829764	48829787	X	-	27260156	MEWO	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.7762347261489868	[283]	[433,449,476]	9	hSpCas9	negative selection	7545841
48829668	48829691	X	-	27260156	MEWO	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.04269931948065492	[537]	[541,477,539]	1	hSpCas9	negative selection	7545842
48829186	48829209	X	-	27260156	LNCAPCLONEFGC	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.31818410516306206	[236]	[212,225,386,265]	5	hSpCas9	negative selection	7602826
48829303	48829326	X	+	27260156	LNCAPCLONEFGC	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.6095366781253523	[590]	[870,727,960,732]	8	hSpCas9	negative selection	7602827
48829312	48829335	X	-	27260156	LNCAPCLONEFGC	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.4127163556673604	[659]	[744,822,767,841]	6	hSpCas9	negative selection	7602828
48829269	48829292	X	-	27260156	LNCAPCLONEFGC	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.4120077210011359	[1634]	[1800,1904,2362,1877]	6	hSpCas9	negative selection	7667091
48829764	48829787	X	-	27260156	LNCAPCLONEFGC	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.2534879026622892	[283]	[262,308,338,320]	4	hSpCas9	negative selection	7667092
48829668	48829691	X	-	27260156	LNCAPCLONEFGC	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.2151867310738106	[537]	[610,457,822,414]	3	hSpCas9	negative selection	7667093
48829186	48829209	X	-	27260156	PANC0327	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.1310980181652075	[236]	[246,124,165,243]	-2	hSpCas9	negative selection	7724077
48829303	48829326	X	+	27260156	PANC0327	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.7172262217194094	[590]	[1227,829,649,777]	9	hSpCas9	negative selection	7724078
48829312	48829335	X	-	27260156	PANC0327	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.11153599661772584	[659]	[675,655,608,592]	1	hSpCas9	negative selection	7724079
48829269	48829292	X	-	27260156	PANC0327	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.4983803204328703	[1634]	[2128,2319,2036,1691]	7	hSpCas9	negative selection	7788342
48829764	48829787	X	-	27260156	PANC0327	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.3420472959254316	[283]	[275,190,350,473]	5	hSpCas9	negative selection	7788343
48829668	48829691	X	-	27260156	PANC0327	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.1968108697447266	[537]	[543,336,707,628]	3	hSpCas9	negative selection	7788344
48829186	48829209	X	-	27260156	NCIH2009	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.0015034800982148822	[236]	[425,363,219]	0	hSpCas9	negative selection	7845328
48829303	48829326	X	+	27260156	NCIH2009	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.5579883070501589	[590]	[1418,1217,1047]	7	hSpCas9	negative selection	7845329
48829312	48829335	X	-	27260156	NCIH2009	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.28643316089520254	[659]	[1512,891,1047]	4	hSpCas9	negative selection	7845330
48829269	48829292	X	-	27260156	NCIH2009	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.64905079510827	[1634]	[4172,3373,3313]	8	hSpCas9	negative selection	7909593
48829764	48829787	X	-	27260156	NCIH2009	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.3309618247932619	[283]	[566,437,505]	4	hSpCas9	negative selection	7909594
48829668	48829691	X	-	27260156	NCIH2009	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.14984753142451246	[537]	[926,712,880]	2	hSpCas9	negative selection	7909595
48829186	48829209	X	-	27260156	NCIH1373	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.7516879185864274	[236]	[352,382,247,215]	7	hSpCas9	negative selection	7966579
48829303	48829326	X	+	27260156	NCIH1373	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.9215179653893864	[590]	[1143,1262,1444,296]	8	hSpCas9	negative selection	7966580
48829312	48829335	X	-	27260156	NCIH1373	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.5422268562980742	[659]	[1227,781,1316,268]	5	hSpCas9	negative selection	7966581
48829269	48829292	X	-	27260156	NCIH1373	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.7421948858623406	[1634]	[4849,3012,2378,591]	7	hSpCas9	negative selection	8030844
48829764	48829787	X	-	27260156	NCIH1373	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.6707754921108544	[283]	[346,481,855,77]	6	hSpCas9	negative selection	8030845
48829668	48829691	X	-	27260156	NCIH1373	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.704704568287158	[537]	[1366,882,856,232]	7	hSpCas9	negative selection	8030846
48829186	48829209	X	-	27260156	PATU8902	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.3239429040074986	[236]	[342,323,85,355]	-3	hSpCas9	negative selection	8087830
48829303	48829326	X	+	27260156	PATU8902	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.9680459182663186	[590]	[2104,1493,949,2101]	9	hSpCas9	negative selection	8087831
48829312	48829335	X	-	27260156	PATU8902	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.8218077617808645	[659]	[1598,1886,1555,1440]	8	hSpCas9	negative selection	8087832
48829269	48829292	X	-	27260156	PATU8902	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.8419756549274624	[1634]	[5262,4589,3043,3593]	8	hSpCas9	negative selection	8152095
48829764	48829787	X	-	27260156	PATU8902	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	1.0808727255279689	[283]	[1215,475,737,941]	9	hSpCas9	negative selection	8152096
48829668	48829691	X	-	27260156	PATU8902	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.6946095291605653	[537]	[1102,1486,636,1840]	7	hSpCas9	negative selection	8152097
48829186	48829209	X	-	27260156	PANC1	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.28962067100269107	[236]	[237,386,198,202]	4	hSpCas9	negative selection	8209081
48829303	48829326	X	+	27260156	PANC1	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.6655600812891435	[590]	[835,1150,906,444]	9	hSpCas9	negative selection	8209082
48829312	48829335	X	-	27260156	PANC1	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.4451647609855731	[659]	[662,892,783,762]	7	hSpCas9	negative selection	8209083
48829269	48829292	X	-	27260156	PANC1	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.050707336615189336	[1634]	[1360,1736,1633,1170]	0	hSpCas9	negative selection	8273346
48829764	48829787	X	-	27260156	PANC1	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.5270804820115105	[283]	[297,440,424,269]	8	hSpCas9	negative selection	8273347
48829668	48829691	X	-	27260156	PANC1	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.45757645963657856	[537]	[857,693,448,546]	7	hSpCas9	negative selection	8273348
48829186	48829209	X	-	27260156	PANC0813	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.13232305433051605	[236]	[362,230,368,264]	2	hSpCas9	negative selection	8330332
48829303	48829326	X	+	27260156	PANC0813	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.4954178389332179	[590]	[1359,976,792,825]	7	hSpCas9	negative selection	8330333
48829312	48829335	X	-	27260156	PANC0813	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.21188719636829678	[659]	[1199,996,740,690]	3	hSpCas9	negative selection	8330334
48829269	48829292	X	-	27260156	PANC0813	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.5295869767309174	[1634]	[2917,2628,2533,3002]	8	hSpCas9	negative selection	8394597
48829764	48829787	X	-	27260156	PANC0813	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.30017876169511765	[283]	[557,398,366,335]	5	hSpCas9	negative selection	8394598
48829668	48829691	X	-	27260156	PANC0813	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.22490768080477874	[537]	[858,714,534,847]	3	hSpCas9	negative selection	8394599
48829186	48829209	X	-	27260156	RDES	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.35694755065799577	[236]	[280,312,394,428]	6	hSpCas9	negative selection	8451583
48829303	48829326	X	+	27260156	RDES	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.47571626895929553	[590]	[759,705,1206,1190]	7	hSpCas9	negative selection	8451584
48829312	48829335	X	-	27260156	RDES	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.5026896747077938	[659]	[891,916,1434,1096]	7	hSpCas9	negative selection	8451585
48829269	48829292	X	-	27260156	RDES	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.20108663353583522	[1634]	[1853,1738,2440,2754]	3	hSpCas9	negative selection	8515848
48829764	48829787	X	-	27260156	RDES	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.23369814575151926	[283]	[303,306,337,637]	4	hSpCas9	negative selection	8515849
48829668	48829691	X	-	27260156	RDES	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.47475293616642533	[537]	[637,851,996,1002]	7	hSpCas9	negative selection	8515850
48829186	48829209	X	-	27260156	PC3	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.2181785204661597	[236]	[114,246,286,213]	-5	hSpCas9	negative selection	8572834
48829303	48829326	X	+	27260156	PC3	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.36976643080938	[590]	[516,573,1391,850]	7	hSpCas9	negative selection	8572835
48829312	48829335	X	-	27260156	PC3	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.1367693646054402	[659]	[405,611,1333,867]	3	hSpCas9	negative selection	8572836
48829269	48829292	X	-	27260156	PC3	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.24004775713115944	[1634]	[1191,1497,3392,2370]	5	hSpCas9	negative selection	8637099
48829764	48829787	X	-	27260156	PC3	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.11310647438847654	[283]	[132,262,417,331]	-3	hSpCas9	negative selection	8637100
48829668	48829691	X	-	27260156	PC3	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.0038396183756793933	[537]	[411,575,597,578]	0	hSpCas9	negative selection	8637101
48829186	48829209	X	-	27260156	PATU8988T	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.007790913202294747	[236]	[258,151,164,347]	0	hSpCas9	negative selection	8694085
48829303	48829326	X	+	27260156	PATU8988T	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.6408129992655281	[590]	[1161,1006,436,979]	9	hSpCas9	negative selection	8694086
48829312	48829335	X	-	27260156	PATU8988T	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.3522682956113493	[659]	[890,918,659,796]	6	hSpCas9	negative selection	8694087
48829269	48829292	X	-	27260156	PATU8988T	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.24926608756547242	[1634]	[1951,1893,1612,2072]	4	hSpCas9	negative selection	8758350
48829764	48829787	X	-	27260156	PATU8988T	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.29661970034661417	[283]	[524,190,431,171]	5	hSpCas9	negative selection	8758351
48829668	48829691	X	-	27260156	PATU8988T	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.05983622659188248	[537]	[415,600,563,595]	1	hSpCas9	negative selection	8758352
48829186	48829209	X	-	27260156	T47D	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.09401576326487027	[236]	[258,278,286,356]	2	hSpCas9	negative selection	8815336
48829303	48829326	X	+	27260156	T47D	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.3727722866809422	[590]	[1063,724,855,937]	7	hSpCas9	negative selection	8815337
48829312	48829335	X	-	27260156	T47D	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.11629411670618939	[659]	[921,670,871,883]	2	hSpCas9	negative selection	8815338
48829269	48829292	X	-	27260156	T47D	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.24631132802152478	[1634]	[2292,2016,2248,2506]	5	hSpCas9	negative selection	8879601
48829764	48829787	X	-	27260156	T47D	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.16645218870495204	[283]	[401,363,333,386]	3	hSpCas9	negative selection	8879602
48829668	48829691	X	-	27260156	T47D	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.1307260835233338	[537]	[827,639,588,693]	2	hSpCas9	negative selection	8879603
48829186	48829209	X	-	27260156	SU8686	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.02551293789794573	[236]	[198,293,248,204]	0	hSpCas9	negative selection	8936587
48829303	48829326	X	+	27260156	SU8686	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.4402005958454437	[590]	[663,897,720,908]	7	hSpCas9	negative selection	8936588
48829312	48829335	X	-	27260156	SU8686	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.17274362599579973	[659]	[581,724,796,885]	3	hSpCas9	negative selection	8936589
48829269	48829292	X	-	27260156	SU8686	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.3920619125932989	[1634]	[1901,1894,2321,2494]	6	hSpCas9	negative selection	9000852
48829764	48829787	X	-	27260156	SU8686	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.6679028582392892	[283]	[467,467,448,385]	9	hSpCas9	negative selection	9000853
48829668	48829691	X	-	27260156	SU8686	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.3174334435792565	[537]	[656,634,630,747]	5	hSpCas9	negative selection	9000854
48829186	48829209	X	-	27260156	SKES1	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.11205056125752944	[236]	[173,326,295,222]	2	hSpCas9	negative selection	9057838
48829303	48829326	X	+	27260156	SKES1	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.5046711315950558	[590]	[908,891,798,762]	8	hSpCas9	negative selection	9057839
48829312	48829335	X	-	27260156	SKES1	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.2784976712211399	[659]	[650,1077,739,737]	6	hSpCas9	negative selection	9057840
48829269	48829292	X	-	27260156	SKES1	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.266083048940309	[1634]	[1939,1814,2199,1857]	5	hSpCas9	negative selection	9122103
48829764	48829787	X	-	27260156	SKES1	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.34492399443458627	[283]	[559,285,324,291]	7	hSpCas9	negative selection	9122104
48829668	48829691	X	-	27260156	SKES1	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.21408333134062357	[537]	[614,659,658,559]	4	hSpCas9	negative selection	9122105
48829186	48829209	X	-	27260156	TOV112D	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.10014040738634855	[236]	[173,396,253,102]	-2	hSpCas9	negative selection	9179089
48829303	48829326	X	+	27260156	TOV112D	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.6146084299072891	[590]	[906,1076,637,1039]	9	hSpCas9	negative selection	9179090
48829312	48829335	X	-	27260156	TOV112D	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.380573877151408	[659]	[752,828,836,1000]	7	hSpCas9	negative selection	9179091
48829269	48829292	X	-	27260156	TOV112D	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.18215867004558595	[1634]	[1663,2157,2128,1543]	3	hSpCas9	negative selection	9243354
48829764	48829787	X	-	27260156	TOV112D	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	-0.14492318709955465	[283]	[186,279,293,266]	-3	hSpCas9	negative selection	9243355
48829668	48829691	X	-	27260156	TOV112D	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	-0.08569668688763422	[537]	[559,727,372,429]	-2	hSpCas9	negative selection	9243356
48829186	48829209	X	-	27260156	TC71	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	-0.3213762745649591	[236]	[135,268,192,217]	-7	hSpCas9	negative selection	9300340
48829303	48829326	X	+	27260156	TC71	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.3562023258203758	[590]	[718,864,853,805]	8	hSpCas9	negative selection	9300341
48829312	48829335	X	-	27260156	TC71	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.1782486519925417	[659]	[869,775,724,833]	4	hSpCas9	negative selection	9300342
48829269	48829292	X	-	27260156	TC71	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.2314855066828232	[1634]	[2181,2200,1827,2021]	6	hSpCas9	negative selection	9364605
48829764	48829787	X	-	27260156	TC71	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.12083714338043094	[283]	[264,379,288,396]	3	hSpCas9	negative selection	9364606
48829668	48829691	X	-	27260156	TC71	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.11032529260990309	[537]	[587,619,605,680]	3	hSpCas9	negative selection	9364607
48829186	48829209	X	-	27260156	TC32	viability	GAGCCCGGTGGGTTTCCCCCTGG	ERAS	ENSG00000187682	0.2523673570955326	[236]	[220,231,306,312]	4	hSpCas9	negative selection	9421591
48829303	48829326	X	+	27260156	TC32	viability	GCTGAACCACCAGTGCTTCGTGG	ERAS	ENSG00000187682	0.40863137322332854	[590]	[735,381,1136,864]	7	hSpCas9	negative selection	9421592
48829312	48829335	X	-	27260156	TC32	viability	CGTGGTCCTCCACGAAGCACTGG	ERAS	ENSG00000187682	0.18351131683029887	[659]	[654,456,1029,796]	3	hSpCas9	negative selection	9421593
48829269	48829292	X	-	27260156	TC32	viability	CGCACTCTTGCCCACGCCACTGG	ERAS	ENSG00000187682	0.20000211790642464	[1634]	[1833,1236,2066,2076]	3	hSpCas9	negative selection	9485856
48829764	48829787	X	-	27260156	TC32	viability	GTGCCGGGTCTTCTCCCTACAGG	ERAS	ENSG00000187682	0.29330957162185195	[283]	[225,246,501,391]	5	hSpCas9	negative selection	9485857
48829668	48829691	X	-	27260156	TC32	viability	CTCCACGCCTTGCCGTGTTTTGG	ERAS	ENSG00000187682	0.3451643864313778	[537]	[800,355,812,680]	6	hSpCas9	negative selection	9485858
48829300	48829323	X	-	27869803	HPAFII	viability after 27 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.29848762510414284	[130]	[109,10,NaN]	-2	hSpCas9	negative selection	9608949
48829354	48829377	X	+	27869803	HPAFII	viability after 27 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.8613809818822943	[332]	[79,109,NaN]	-6	hSpCas9	negative selection	9608950
48829435	48829458	X	-	27869803	HPAFII	viability after 27 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.1190696389231179	[279]	[194,85,NaN]	-1	hSpCas9	negative selection	9608951
48829444	48829467	X	-	27869803	HPAFII	viability after 27 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.6541524390203823	[346]	[381,207,NaN]	5	hSpCas9	negative selection	9608952
48829701	48829724	X	-	27869803	HPAFII	viability after 27 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.927580454375704	[0]	[0,0,NaN]	7	hSpCas9	negative selection	9608953
48829300	48829323	X	-	27869803	HPAFII	viability after 15 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.34217792569660554	[130]	[234,33,NaN]	-4	hSpCas9	negative selection	9691398
48829354	48829377	X	+	27869803	HPAFII	viability after 15 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.08782229997264623	[332]	[501,233,NaN]	-1	hSpCas9	negative selection	9691399
48829435	48829458	X	-	27869803	HPAFII	viability after 15 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.0898966238541138	[279]	[410,202,NaN]	-1	hSpCas9	negative selection	9691400
48829444	48829467	X	-	27869803	HPAFII	viability after 15 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.9340659237863627	[346]	[981,544,NaN]	8	hSpCas9	negative selection	9691401
48829701	48829724	X	-	27869803	HPAFII	viability after 15 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	-0.10397428375416773	[0]	[0,0,NaN]	-1	hSpCas9	negative selection	9691402
48829300	48829323	X	-	27869803	ASPC1	viability after 36 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.2149849904206249	[388]	[29,282,44]	-2	hSpCas9	negative selection	9773847
48829354	48829377	X	+	27869803	ASPC1	viability after 36 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	0.5896320527074139	[826]	[816,366,214]	6	hSpCas9	negative selection	9773848
48829435	48829458	X	-	27869803	ASPC1	viability after 36 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.2500003821228005	[1005]	[626,14,281]	-3	hSpCas9	negative selection	9773849
48829444	48829467	X	-	27869803	ASPC1	viability after 36 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	-0.41300203795031265	[1028]	[763,99,54]	-4	hSpCas9	negative selection	9773850
48829701	48829724	X	-	27869803	ASPC1	viability after 36 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	-0.45154966635512384	[426]	[192,89,63]	-4	hSpCas9	negative selection	9773851
48829300	48829323	X	-	27869803	PATU8988S	viability after 35 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.2703405597295949	[312]	[169,133,NaN]	3	hSpCas9	negative selection	9856296
48829354	48829377	X	+	27869803	PATU8988S	viability after 35 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.603533301688962	[738]	[144,246,NaN]	-6	hSpCas9	negative selection	9856297
48829435	48829458	X	-	27869803	PATU8988S	viability after 35 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.9609848877849493	[895]	[131,238,NaN]	-7	hSpCas9	negative selection	9856298
48829444	48829467	X	-	27869803	PATU8988S	viability after 35 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.7188471943331675	[798]	[369,689,NaN]	7	hSpCas9	negative selection	9856299
48829701	48829724	X	-	27869803	PATU8988S	viability after 35 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.5912400192532978	[350]	[200,224,NaN]	6	hSpCas9	negative selection	9856300
48829300	48829323	X	-	27869803	PATU8988S	viability after 31 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	0.30804899830128946	[312]	[128,186,NaN]	4	hSpCas9	negative selection	9938745
48829354	48829377	X	+	27869803	PATU8988S	viability after 31 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.3814099019507276	[738]	[106,377,NaN]	-4	hSpCas9	negative selection	9938746
48829435	48829458	X	-	27869803	PATU8988S	viability after 31 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.5771356546516607	[895]	[231,248,NaN]	-6	hSpCas9	negative selection	9938747
48829444	48829467	X	-	27869803	PATU8988S	viability after 31 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.7445293190686474	[798]	[264,875,NaN]	8	hSpCas9	negative selection	9938748
48829701	48829724	X	-	27869803	PATU8988S	viability after 31 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.8647362932094727	[350]	[187,339,NaN]	8	hSpCas9	negative selection	9938749
48829300	48829323	X	-	27869803	HPAFII	viability after 35 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-1.386644755348885	[130]	[46,0,NaN]	-6	hSpCas9	negative selection	10021194
48829354	48829377	X	+	27869803	HPAFII	viability after 35 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.8483537108308856	[332]	[63,126,NaN]	-5	hSpCas9	negative selection	10021195
48829435	48829458	X	-	27869803	HPAFII	viability after 35 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.606871126329853	[279]	[125,55,NaN]	-4	hSpCas9	negative selection	10021196
48829444	48829467	X	-	27869803	HPAFII	viability after 35 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	0.4974930108052894	[346]	[247,247,NaN]	3	hSpCas9	negative selection	10021197
48829701	48829724	X	-	27869803	HPAFII	viability after 35 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.9820885529966752	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10021198
48829300	48829323	X	-	27869803	HPAFII	viability after 31 days	CGAAGCACTGGTGGTTCAGCTGG	ERAS	ENSG00000187682	-0.2213004911456078	[130]	[97,24,NaN]	-1	hSpCas9	negative selection	10103643
48829354	48829377	X	+	27869803	HPAFII	viability after 31 days	CTACTGGAAGGAGTTGACCCTGG	ERAS	ENSG00000187682	-0.9628706592273708	[332]	[81,110,NaN]	-6	hSpCas9	negative selection	10103644
48829435	48829458	X	-	27869803	HPAFII	viability after 31 days	CAGCCAGGCACTGGTCACGCAGG	ERAS	ENSG00000187682	-0.6119146657638782	[279]	[109,94,NaN]	-4	hSpCas9	negative selection	10103645
48829444	48829467	X	-	27869803	HPAFII	viability after 31 days	CATCACAGACAGCCAGGCACTGG	ERAS	ENSG00000187682	1.0676864741303027	[346]	[512,293,NaN]	7	hSpCas9	negative selection	10103646
48829701	48829724	X	-	27869803	HPAFII	viability after 31 days	CTGGATCTCATGGACCAGCAGGG	ERAS	ENSG00000187682	0.8333711996752582	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10103647
48829216	48829239	X	-	28162770	P31FUJ	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-1.3813986964161793	[469]	[211]	-7	hSpCas9	negative selection	10150913
48829422	48829445	X	-	28162770	P31FUJ	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.24283530586843693	[675]	[939]	2	hSpCas9	negative selection	10150914
48829306	48829329	X	+	28162770	P31FUJ	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.07614803647477375	[267]	[331]	0	hSpCas9	negative selection	10150915
48829495	48829518	X	-	28162770	P31FUJ	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	1.016811685657094	[44]	[106]	9	hSpCas9	negative selection	10150916
48829593	48829616	X	-	28162770	P31FUJ	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.45056400036777194	[169]	[272]	5	hSpCas9	negative selection	10150917
48829622	48829645	X	+	28162770	P31FUJ	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.5496593097543191	[283]	[227]	-4	hSpCas9	negative selection	10150918
48829661	48829684	X	+	28162770	P31FUJ	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.8702014877317392	[276]	[594]	8	hSpCas9	negative selection	10150919
48829237	48829260	X	+	28162770	P31FUJ	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.08733260864993292	[160]	[200]	0	hSpCas9	negative selection	10150920
48829361	48829384	X	+	28162770	P31FUJ	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.4374075829252886	[574]	[914]	5	hSpCas9	negative selection	10150921
48829399	48829422	X	+	28162770	P31FUJ	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	1.161189850056636	[163]	[430]	9	hSpCas9	negative selection	10150922
48829216	48829239	X	-	28162770	TF1	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	NaN	[NaN]	[321]	1	hSpCas9	negative selection	10320279
48829422	48829445	X	-	28162770	TF1	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	NaN	[NaN]	[930]	1	hSpCas9	negative selection	10320280
48829306	48829329	X	+	28162770	TF1	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10320281
48829495	48829518	X	-	28162770	TF1	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10320282
48829593	48829616	X	-	28162770	TF1	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	NaN	[NaN]	[237]	1	hSpCas9	negative selection	10320283
48829622	48829645	X	+	28162770	TF1	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	NaN	[NaN]	[256]	1	hSpCas9	negative selection	10320284
48829661	48829684	X	+	28162770	TF1	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	NaN	[NaN]	[454]	1	hSpCas9	negative selection	10320285
48829237	48829260	X	+	28162770	TF1	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10320286
48829361	48829384	X	+	28162770	TF1	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	NaN	[NaN]	[550]	1	hSpCas9	negative selection	10320287
48829399	48829422	X	+	28162770	TF1	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10320288
48829216	48829239	X	-	28162770	SKM1	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.2914869813232256	[134]	[194]	-2	hSpCas9	negative selection	10489645
48829422	48829445	X	-	28162770	SKM1	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.406529860411849	[133]	[313]	4	hSpCas9	negative selection	10489646
48829306	48829329	X	+	28162770	SKM1	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.5168002154297533	[67]	[171]	5	hSpCas9	negative selection	10489647
48829495	48829518	X	-	28162770	SKM1	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	1.2026603562122633	[28]	[117]	9	hSpCas9	negative selection	10489648
48829593	48829616	X	-	28162770	SKM1	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	-0.05950101174866183	[55]	[94]	0	hSpCas9	negative selection	10489649
48829622	48829645	X	+	28162770	SKM1	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-1.2455007760490455	[113]	[84]	-7	hSpCas9	negative selection	10489650
48829661	48829684	X	+	28162770	SKM1	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	-0.2802923952547334	[78]	[114]	-2	hSpCas9	negative selection	10489651
48829237	48829260	X	+	28162770	SKM1	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.016247231981382226	[32]	[58]	0	hSpCas9	negative selection	10489652
48829361	48829384	X	+	28162770	SKM1	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.21013092291880342	[110]	[226]	2	hSpCas9	negative selection	10489653
48829399	48829422	X	+	28162770	SKM1	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.10071772608806906	[36]	[60]	-1	hSpCas9	negative selection	10489654
48829216	48829239	X	-	28162770	SKM1	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.2914869813232256	[134]	[194]	-2	hSpCas9	negative selection	10659011
48829422	48829445	X	-	28162770	SKM1	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.406529860411849	[133]	[313]	4	hSpCas9	negative selection	10659012
48829306	48829329	X	+	28162770	SKM1	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.5168002154297533	[67]	[171]	5	hSpCas9	negative selection	10659013
48829495	48829518	X	-	28162770	SKM1	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	1.2026603562122633	[28]	[117]	9	hSpCas9	negative selection	10659014
48829593	48829616	X	-	28162770	SKM1	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	-0.05950101174866183	[55]	[94]	0	hSpCas9	negative selection	10659015
48829622	48829645	X	+	28162770	SKM1	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-1.2455007760490455	[113]	[84]	-7	hSpCas9	negative selection	10659016
48829661	48829684	X	+	28162770	SKM1	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	-0.2802923952547334	[78]	[114]	-2	hSpCas9	negative selection	10659017
48829237	48829260	X	+	28162770	SKM1	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.016247231981382226	[32]	[58]	0	hSpCas9	negative selection	10659018
48829361	48829384	X	+	28162770	SKM1	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.21013092291880342	[110]	[226]	2	hSpCas9	negative selection	10659019
48829399	48829422	X	+	28162770	SKM1	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.10071772608806906	[36]	[60]	-1	hSpCas9	negative selection	10659020
48829216	48829239	X	-	28162770	PL21	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	0.9005793326304126	[431]	[350]	7	hSpCas9	negative selection	10828377
48829422	48829445	X	-	28162770	PL21	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	1.2558729626495606	[456]	[474]	8	hSpCas9	negative selection	10828378
48829306	48829329	X	+	28162770	PL21	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	-0.4496740305818038	[272]	[86]	-3	hSpCas9	negative selection	10828379
48829495	48829518	X	-	28162770	PL21	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.23666549051443408	[77]	[39]	2	hSpCas9	negative selection	10828380
48829593	48829616	X	-	28162770	PL21	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.5311128489796894	[158]	[99]	4	hSpCas9	negative selection	10828381
48829622	48829645	X	+	28162770	PL21	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	0.16061125030268264	[369]	[179]	1	hSpCas9	negative selection	10828382
48829661	48829684	X	+	28162770	PL21	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.5427911883864818	[234]	[148]	5	hSpCas9	negative selection	10828383
48829237	48829260	X	+	28162770	PL21	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.212630558672517	[114]	[57]	2	hSpCas9	negative selection	10828384
48829361	48829384	X	+	28162770	PL21	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	-0.22815029150343846	[400]	[148]	-2	hSpCas9	negative selection	10828385
48829399	48829422	X	+	28162770	PL21	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.2804862264171005	[119]	[42]	-2	hSpCas9	negative selection	10828386
48829216	48829239	X	-	28162770	P31FUJ	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-1.3813986964161793	[469]	[211]	-7	hSpCas9	negative selection	10997743
48829422	48829445	X	-	28162770	P31FUJ	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.24283530586843693	[675]	[939]	2	hSpCas9	negative selection	10997744
48829306	48829329	X	+	28162770	P31FUJ	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.07614803647477375	[267]	[331]	0	hSpCas9	negative selection	10997745
48829495	48829518	X	-	28162770	P31FUJ	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	1.016811685657094	[44]	[106]	9	hSpCas9	negative selection	10997746
48829593	48829616	X	-	28162770	P31FUJ	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.45056400036777194	[169]	[272]	5	hSpCas9	negative selection	10997747
48829622	48829645	X	+	28162770	P31FUJ	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.5496593097543191	[283]	[227]	-4	hSpCas9	negative selection	10997748
48829661	48829684	X	+	28162770	P31FUJ	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.8702014877317392	[276]	[594]	8	hSpCas9	negative selection	10997749
48829237	48829260	X	+	28162770	P31FUJ	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.08733260864993292	[160]	[200]	0	hSpCas9	negative selection	10997750
48829361	48829384	X	+	28162770	P31FUJ	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.4374075829252886	[574]	[914]	5	hSpCas9	negative selection	10997751
48829399	48829422	X	+	28162770	P31FUJ	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	1.161189850056636	[163]	[430]	9	hSpCas9	negative selection	10997752
48829216	48829239	X	-	28162770	OCIAML5	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.004896186841472527	[193]	[348]	0	hSpCas9	negative selection	11167109
48829422	48829445	X	-	28162770	OCIAML5	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	1.1324268428684943	[303]	[1202]	8	hSpCas9	negative selection	11167110
48829306	48829329	X	+	28162770	OCIAML5	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	-0.4966785600313095	[178]	[228]	-3	hSpCas9	negative selection	11167111
48829495	48829518	X	-	28162770	OCIAML5	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.1818807610593407	[41]	[85]	1	hSpCas9	negative selection	11167112
48829593	48829616	X	-	28162770	OCIAML5	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.3530478590406154	[107]	[248]	3	hSpCas9	negative selection	11167113
48829622	48829645	X	+	28162770	OCIAML5	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.7864782292364203	[214]	[224]	-5	hSpCas9	negative selection	11167114
48829661	48829684	X	+	28162770	OCIAML5	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.45668613527563195	[175]	[435]	4	hSpCas9	negative selection	11167115
48829237	48829260	X	+	28162770	OCIAML5	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	1.6206864262711342	[48]	[271]	9	hSpCas9	negative selection	11167116
48829361	48829384	X	+	28162770	OCIAML5	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.4060247852969714	[267]	[640]	3	hSpCas9	negative selection	11167117
48829399	48829422	X	+	28162770	OCIAML5	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	0.6681902404693438	[75]	[217]	6	hSpCas9	negative selection	11167118
48829216	48829239	X	-	28162770	EOL1	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.5812817681872473	[939]	[330]	-4	hSpCas9	negative selection	11336475
48829422	48829445	X	-	28162770	EOL1	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.3395852708493783	[641]	[427]	3	hSpCas9	negative selection	11336476
48829306	48829329	X	+	28162770	EOL1	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	-0.0809904119708954	[521]	[259]	0	hSpCas9	negative selection	11336477
48829495	48829518	X	-	28162770	EOL1	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	-1.2453772298717778	[125]	[27]	-7	hSpCas9	negative selection	11336478
48829593	48829616	X	-	28162770	EOL1	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.44827609965574194	[376]	[270]	4	hSpCas9	negative selection	11336479
48829622	48829645	X	+	28162770	EOL1	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.6893937961223876	[703]	[229]	-5	hSpCas9	negative selection	11336480
48829661	48829684	X	+	28162770	EOL1	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.15097570614213923	[305]	[178]	1	hSpCas9	negative selection	11336481
48829237	48829260	X	+	28162770	EOL1	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	-0.4839170737848233	[145]	[54]	-4	hSpCas9	negative selection	11336482
48829361	48829384	X	+	28162770	EOL1	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.3159237946154745	[583]	[382]	3	hSpCas9	negative selection	11336483
48829399	48829422	X	+	28162770	EOL1	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.5135733408213503	[167]	[61]	-4	hSpCas9	negative selection	11336484
48829216	48829239	X	-	28162770	MOLM13	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.682235377163602	[596]	[268]	-4	hSpCas9	negative selection	11505841
48829422	48829445	X	-	28162770	MOLM13	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.3662491196687414	[734]	[684]	2	hSpCas9	negative selection	11505842
48829306	48829329	X	+	28162770	MOLM13	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.4716221004209087	[385]	[386]	3	hSpCas9	negative selection	11505843
48829495	48829518	X	-	28162770	MOLM13	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.4678893815445788	[99]	[99]	3	hSpCas9	negative selection	11505844
48829593	48829616	X	-	28162770	MOLM13	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	1.5931406444704952	[214]	[468]	9	hSpCas9	negative selection	11505845
48829622	48829645	X	+	28162770	MOLM13	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-1.0081889030247253	[522]	[187]	-5	hSpCas9	negative selection	11505846
48829661	48829684	X	+	28162770	MOLM13	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.4678893815445788	[396]	[396]	3	hSpCas9	negative selection	11505847
48829237	48829260	X	+	28162770	MOLM13	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	-0.33208601014742756	[194]	[111]	-2	hSpCas9	negative selection	11505848
48829361	48829384	X	+	28162770	MOLM13	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.9724581024149911	[491]	[697]	7	hSpCas9	negative selection	11505849
48829399	48829422	X	+	28162770	MOLM13	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	0.6782492473861297	[171]	[198]	5	hSpCas9	negative selection	11505850
48829216	48829239	X	-	28162770	HEL	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	0.00016560810910570822	[561]	[359]	0	hSpCas9	negative selection	11675207
48829422	48829445	X	-	28162770	HEL	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.40258629666745627	[612]	[518]	3	hSpCas9	negative selection	11675208
48829306	48829329	X	+	28162770	HEL	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	1.2036056571040503	[321]	[474]	9	hSpCas9	negative selection	11675209
48829495	48829518	X	-	28162770	HEL	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	1.7927642760049645	[72]	[161]	9	hSpCas9	negative selection	11675210
48829593	48829616	X	-	28162770	HEL	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.9379365612731975	[206]	[253]	7	hSpCas9	negative selection	11675211
48829622	48829645	X	+	28162770	HEL	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.3829097553702533	[453]	[222]	-3	hSpCas9	negative selection	11675212
48829661	48829684	X	+	28162770	HEL	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.1693680224051859	[285]	[205]	1	hSpCas9	negative selection	11675213
48829237	48829260	X	+	28162770	HEL	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.7532972071480555	[112]	[121]	6	hSpCas9	negative selection	11675214
48829361	48829384	X	+	28162770	HEL	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.3569553008480896	[472]	[387]	3	hSpCas9	negative selection	11675215
48829399	48829422	X	+	28162770	HEL	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	1.526414714033125	[141]	[261]	9	hSpCas9	negative selection	11675216
48829216	48829239	X	-	28162770	MV411	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.32712977857600256	[483]	[324]	-2	hSpCas9	negative selection	11844573
48829422	48829445	X	-	28162770	MV411	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.929311026055269	[378]	[607]	8	hSpCas9	negative selection	11844574
48829306	48829329	X	+	28162770	MV411	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.46897453477373996	[240]	[280]	4	hSpCas9	negative selection	11844575
48829495	48829518	X	-	28162770	MV411	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.032698701989762546	[93]	[80]	0	hSpCas9	negative selection	11844576
48829593	48829616	X	-	28162770	MV411	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.032169563879708846	[201]	[173]	0	hSpCas9	negative selection	11844577
48829622	48829645	X	+	28162770	MV411	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.4602074697132094	[275]	[168]	-3	hSpCas9	negative selection	11844578
48829661	48829684	X	+	28162770	MV411	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.857491032466762	[189]	[289]	7	hSpCas9	negative selection	11844579
48829237	48829260	X	+	28162770	MV411	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.41182436868365774	[115]	[129]	3	hSpCas9	negative selection	11844580
48829361	48829384	X	+	28162770	MV411	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.6221823441135858	[353]	[458]	5	hSpCas9	negative selection	11844581
48829399	48829422	X	+	28162770	MV411	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	0.3774980913471483	[158]	[173]	3	hSpCas9	negative selection	11844582
48829216	48829239	X	-	28162770	MONOMAC1	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.7388016583796074	[328]	[225]	-6	hSpCas9	negative selection	12013939
48829422	48829445	X	-	28162770	MONOMAC1	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.15619536774581833	[309]	[395]	1	hSpCas9	negative selection	12013940
48829306	48829329	X	+	28162770	MONOMAC1	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.34269639966860466	[215]	[313]	3	hSpCas9	negative selection	12013941
48829495	48829518	X	-	28162770	MONOMAC1	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.42187298558494013	[27]	[42]	4	hSpCas9	negative selection	12013942
48829593	48829616	X	-	28162770	MONOMAC1	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	-0.4655256829854556	[105]	[87]	-4	hSpCas9	negative selection	12013943
48829622	48829645	X	+	28162770	MONOMAC1	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	0.7286802713214435	[268]	[510]	7	hSpCas9	negative selection	12013944
48829661	48829684	X	+	28162770	MONOMAC1	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.33269613294121025	[141]	[204]	3	hSpCas9	negative selection	12013945
48829237	48829260	X	+	28162770	MONOMAC1	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	2.4569672980912536	[67]	[427]	9	hSpCas9	negative selection	12013946
48829361	48829384	X	+	28162770	MONOMAC1	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	-0.1472838118624542	[227]	[235]	-1	hSpCas9	negative selection	12013947
48829399	48829422	X	+	28162770	MONOMAC1	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.6756904456343691	[84]	[60]	-5	hSpCas9	negative selection	12013948
48829216	48829239	X	-	28162770	OCIAML2	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.7430020956552913	[92]	[307]	-5	hSpCas9	negative selection	12183305
48829422	48829445	X	-	28162770	OCIAML2	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	1.3256910465404663	[74]	[1041]	9	hSpCas9	negative selection	12183306
48829306	48829329	X	+	28162770	OCIAML2	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.6214545737485557	[54]	[468]	6	hSpCas9	negative selection	12183307
48829495	48829518	X	-	28162770	OCIAML2	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	-0.200540661874417	[16]	[81]	-2	hSpCas9	negative selection	12183308
48829593	48829616	X	-	28162770	OCIAML2	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	0.13063448780809545	[43]	[266]	1	hSpCas9	negative selection	12183309
48829622	48829645	X	+	28162770	OCIAML2	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.30309933894023167	[66]	[300]	-2	hSpCas9	negative selection	12183310
48829661	48829684	X	+	28162770	OCIAML2	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.15386103966563225	[47]	[295]	1	hSpCas9	negative selection	12183311
48829237	48829260	X	+	28162770	OCIAML2	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.6618204707814882	[12]	[113]	6	hSpCas9	negative selection	12183312
48829361	48829384	X	+	28162770	OCIAML2	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	0.5072688823293854	[73]	[582]	5	hSpCas9	negative selection	12183313
48829399	48829422	X	+	28162770	OCIAML2	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	-0.31738356494647935	[28]	[128]	-3	hSpCas9	negative selection	12183314
48829216	48829239	X	-	28162770	OCIAML3	viability	GCTGCCTGCCAACATCCCTGCGG	ERAS	ENSG00000187682	-0.3563160826048324	[133]	[315]	-3	hSpCas9	negative selection	12352671
48829422	48829445	X	-	28162770	OCIAML3	viability	GTCACGCAGGGCCCTATGGATGG	ERAS	ENSG00000187682	0.31745568507417943	[167]	[631]	3	hSpCas9	negative selection	12352672
48829306	48829329	X	+	28162770	OCIAML3	viability	GAACCACCAGTGCTTCGTGGAGG	ERAS	ENSG00000187682	0.9720958331456773	[76]	[455]	8	hSpCas9	negative selection	12352673
48829495	48829518	X	-	28162770	OCIAML3	viability	GCAGCTGGATCAGAGACGAGGGG	ERAS	ENSG00000187682	0.33199177823206005	[14]	[56]	3	hSpCas9	negative selection	12352674
48829593	48829616	X	-	28162770	OCIAML3	viability	GGCATGAGCATCTCCAGCAGTGG	ERAS	ENSG00000187682	1.9720463978469285	[31]	[378]	9	hSpCas9	negative selection	12352675
48829622	48829645	X	+	28162770	OCIAML3	viability	GCAGCCCTCGCACACAGCTGGGG	ERAS	ENSG00000187682	-0.21195855299922994	[93]	[244]	-2	hSpCas9	negative selection	12352676
48829661	48829684	X	+	28162770	OCIAML3	viability	ACCTCGGCCAAAACACGGCAAGG	ERAS	ENSG00000187682	0.07384786874533789	[61]	[196]	0	hSpCas9	negative selection	12352677
48829237	48829260	X	+	28162770	OCIAML3	viability	GCTGCCTGAGTACAAGGCTGTGG	ERAS	ENSG00000187682	0.21334728173344109	[33]	[118]	2	hSpCas9	negative selection	12352678
48829361	48829384	X	+	28162770	OCIAML3	viability	AAGGAGTTGACCCTGGACAGTGG	ERAS	ENSG00000187682	1.113461056597546	[125]	[822]	8	hSpCas9	negative selection	12352679
48829399	48829422	X	+	28162770	OCIAML3	viability	TGTGCTGGACACAGCAGGGCAGG	ERAS	ENSG00000187682	0.485719552146571	[43]	[185]	4	hSpCas9	negative selection	12352680