Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2064
• Symbol:ERBB2
• Description:erb-b2 receptor tyrosine kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ERBB2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
39715845	39715868	17	-	26472758	Jiyoye	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	-0.0012894638494842514	[72]	[54]	0	hSpCas9	negative selection	51315
39715795	39715818	17	+	26472758	Jiyoye	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.449989840322672	[220]	[121]	-3	hSpCas9	negative selection	51316
39723436	39723459	17	+	26472758	Jiyoye	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	3.7048559301465582	[5]	[58]	9	hSpCas9	negative selection	51317
39708378	39708401	17	-	26472758	Jiyoye	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.8283130803211353	[117]	[157]	6	hSpCas9	negative selection	51318
39708472	39708495	17	-	26472758	Jiyoye	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	0.9921378822270294	[55]	[83]	6	hSpCas9	negative selection	51319
39710357	39710380	17	-	26472758	Jiyoye	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	0.4071753815058735	[213]	[213]	3	hSpCas9	negative selection	51320
39710418	39710441	17	+	26472758	Jiyoye	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.19548912094874152	[163]	[107]	-1	hSpCas9	negative selection	51321
39711994	39712017	17	+	26472758	Jiyoye	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.28054194297485624	[118]	[108]	2	hSpCas9	negative selection	51322
39715307	39715330	17	-	26472758	Jiyoye	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	51323
39715486	39715509	17	-	26472758	Jiyoye	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.6028087070667487	[144]	[71]	-4	hSpCas9	negative selection	51324
39687975	39687998	17	-	26472758	Jiyoye	viability	GCGGTTGGTCCTGCTAGCTGGGG	ERBB2	ENSG00000141736	0.7257048999313709	[84]	[105]	5	hSpCas9	negative selection	119383
39687999	39688022	17	-	26472758	Jiyoye	viability	AGAAAGGATGGCCGGCCTGGCGG	ERBB2	ENSG00000141736	0.03305107549308273	[196]	[151]	0	hSpCas9	negative selection	119390
39715845	39715868	17	-	26472758	KBM7	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	-0.6293054966153138	[431,370]	[136,107]	-5	hSpCas9	negative selection	242433
39715795	39715818	17	+	26472758	KBM7	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	0.1271223702390326	[697,663]	[274,417]	1	hSpCas9	negative selection	242434
39723436	39723459	17	+	26472758	KBM7	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	0.15756836355620585	[278,197]	[75,165]	1	hSpCas9	negative selection	242435
39708378	39708401	17	-	26472758	KBM7	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.3666897680420474	[718,502]	[449,289]	4	hSpCas9	negative selection	242436
39708472	39708495	17	-	26472758	KBM7	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.3796454142807888	[259,203]	[97,69]	-3	hSpCas9	negative selection	242437
39710357	39710380	17	-	26472758	KBM7	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.42951653842035636	[939,612]	[302,233]	-4	hSpCas9	negative selection	242438
39710418	39710441	17	+	26472758	KBM7	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.03470530934665239	[809,621]	[394,263]	0	hSpCas9	negative selection	242439
39711994	39712017	17	+	26472758	KBM7	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-0.699962859859686	[459,436]	[146,114]	-5	hSpCas9	negative selection	242440
39715307	39715330	17	-	26472758	KBM7	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-1.1539815176157293	[79,24]	[18,2]	-7	hSpCas9	negative selection	242441
39715486	39715509	17	-	26472758	KBM7	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.34438459278761036	[750,510]	[158,293]	-3	hSpCas9	negative selection	242442
39687975	39687998	17	-	26472758	KBM7	viability	GCGGTTGGTCCTGCTAGCTGGGG	ERBB2	ENSG00000141736	-0.18289543468658653	[358,229]	[169,74]	-2	hSpCas9	negative selection	310501
39687999	39688022	17	-	26472758	KBM7	viability	AGAAAGGATGGCCGGCCTGGCGG	ERBB2	ENSG00000141736	0.3153867923600482	[841,471]	[380,369]	3	hSpCas9	negative selection	310508
39715845	39715868	17	-	26472758	Raji	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	-0.31345958558645015	[165]	[30]	-3	hSpCas9	negative selection	433551
39715795	39715818	17	+	26472758	Raji	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.5909607647652992	[343]	[52]	-5	hSpCas9	negative selection	433552
39723436	39723459	17	+	26472758	Raji	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	0.4069438172325075	[38]	[11]	4	hSpCas9	negative selection	433553
39708378	39708401	17	-	26472758	Raji	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.4262057193931401	[278]	[86]	4	hSpCas9	negative selection	433554
39708472	39708495	17	-	26472758	Raji	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	0.37803112531726846	[188]	[56]	3	hSpCas9	negative selection	433555
39710357	39710380	17	-	26472758	Raji	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.03846733108985545	[415]	[93]	0	hSpCas9	negative selection	433556
39710418	39710441	17	+	26472758	Raji	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.5914922855510563	[460]	[70]	-5	hSpCas9	negative selection	433557
39711994	39712017	17	+	26472758	Raji	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.2485595983342939	[213]	[58]	2	hSpCas9	negative selection	433558
39715307	39715330	17	-	26472758	Raji	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-3.6739761781510603	[54]	[0]	-9	hSpCas9	negative selection	433559
39715486	39715509	17	-	26472758	Raji	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.9984111286489974	[395]	[45]	-6	hSpCas9	negative selection	433560
39687975	39687998	17	-	26472758	Raji	viability	GCGGTTGGTCCTGCTAGCTGGGG	ERBB2	ENSG00000141736	-0.846812775013276	[123]	[15]	-6	hSpCas9	negative selection	501619
39687999	39688022	17	-	26472758	Raji	viability	AGAAAGGATGGCCGGCCTGGCGG	ERBB2	ENSG00000141736	-0.5467934600788451	[490]	[77]	-4	hSpCas9	negative selection	501626
39715845	39715868	17	-	26472758	K562	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	-0.17865609067781518	[239]	[178]	-1	hSpCas9	negative selection	624669
39715795	39715818	17	+	26472758	K562	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.22797462967101245	[572]	[412]	-1	hSpCas9	negative selection	624670
39723436	39723459	17	+	26472758	K562	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.1265635915344614	[171]	[132]	-1	hSpCas9	negative selection	624671
39708378	39708401	17	-	26472758	K562	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	-0.44800847042326103	[605]	[374]	-3	hSpCas9	negative selection	624672
39708472	39708495	17	-	26472758	K562	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.16114601899211445	[252]	[190]	-1	hSpCas9	negative selection	624673
39710357	39710380	17	-	26472758	K562	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.7162070339994087	[505]	[259]	-4	hSpCas9	negative selection	624674
39710418	39710441	17	+	26472758	K562	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.4942531884501624	[563]	[337]	-3	hSpCas9	negative selection	624675
39711994	39712017	17	+	26472758	K562	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.886337113199679	[297]	[464]	7	hSpCas9	negative selection	624676
39715307	39715330	17	-	26472758	K562	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-0.4383910964528539	[60]	[37]	-3	hSpCas9	negative selection	624677
39715486	39715509	17	-	26472758	K562	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	0.21453444772054883	[438]	[429]	1	hSpCas9	negative selection	624678
39687975	39687998	17	-	26472758	K562	viability	GCGGTTGGTCCTGCTAGCTGGGG	ERBB2	ENSG00000141736	0.5485721208258331	[293]	[362]	4	hSpCas9	negative selection	692737
39687999	39688022	17	-	26472758	K562	viability	AGAAAGGATGGCCGGCCTGGCGG	ERBB2	ENSG00000141736	-0.027660817770353813	[447]	[370]	0	hSpCas9	negative selection	692744
39700220	39700243	17	+	26627737	DLD1	viability	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.5317759265683629	[740]	[319,307,369]	5	hSpCas9	negative selection	797433
39707049	39707072	17	+	26627737	DLD1	viability	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-1.2915080809098884	[678]	[141,77,45]	-8	hSpCas9	negative selection	797434
39708439	39708462	17	-	26627737	DLD1	viability	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	-1.0009467377311652	[647]	[99,80,118]	-7	hSpCas9	negative selection	797436
39709313	39709336	17	+	26627737	DLD1	viability	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.3794929377686045	[559]	[87,218,104]	-4	hSpCas9	negative selection	797437
39709817	39709840	17	-	26627737	DLD1	viability	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.0004934510722086616	[768]	[226,393,124]	0	hSpCas9	negative selection	797438
39710088	39710111	17	+	26627737	DLD1	viability	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.22540677279787796	[501]	[62,233,245]	2	hSpCas9	negative selection	797439
39700220	39700243	17	+	26627737	GBM cells	viability after 5 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.24685726484785003	[384]	[167,179]	-4	hSpCas9	negative selection	879748
39707049	39707072	17	+	26627737	GBM cells	viability after 5 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.25214608969105773	[309]	[205,189]	4	hSpCas9	negative selection	879749
39708439	39708462	17	-	26627737	GBM cells	viability after 5 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.8758302617726446	[251]	[217,277]	9	hSpCas9	negative selection	879751
39709313	39709336	17	+	26627737	GBM cells	viability after 5 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.6210444278889496	[390]	[298,345]	8	hSpCas9	negative selection	879752
39709817	39709840	17	-	26627737	GBM cells	viability after 5 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.29100304119044895	[601]	[395,393]	4	hSpCas9	negative selection	879753
39710088	39710111	17	+	26627737	GBM cells	viability after 5 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.26318826048264277	[187]	[86,154]	4	hSpCas9	negative selection	879754
39700220	39700243	17	+	26627737	GBM cells	viability after 13 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.05126867643823951	[384]	[291,154]	0	hSpCas9	negative selection	962063
39707049	39707072	17	+	26627737	GBM cells	viability after 13 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.1758901574062755	[309]	[205,176]	2	hSpCas9	negative selection	962064
39708439	39708462	17	-	26627737	GBM cells	viability after 13 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.9615804375844839	[251]	[332,211]	9	hSpCas9	negative selection	962066
39709313	39709336	17	+	26627737	GBM cells	viability after 13 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.5520878430845017	[390]	[272,341]	7	hSpCas9	negative selection	962067
39709817	39709840	17	-	26627737	GBM cells	viability after 13 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.30855801239483704	[601]	[489,334]	4	hSpCas9	negative selection	962068
39710088	39710111	17	+	26627737	GBM cells	viability after 13 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.08328550765447817	[187]	[101,112]	1	hSpCas9	negative selection	962069
39700220	39700243	17	+	26627737	GBM cells	viability after 21 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.11287159104594047	[384]	[206,180]	-1	hSpCas9	negative selection	1044378
39707049	39707072	17	+	26627737	GBM cells	viability after 21 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.13921143101462435	[309]	[185,184]	1	hSpCas9	negative selection	1044379
39708439	39708462	17	-	26627737	GBM cells	viability after 21 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.9846291311401367	[251]	[272,268]	8	hSpCas9	negative selection	1044381
39709313	39709336	17	+	26627737	GBM cells	viability after 21 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.5725833720073096	[390]	[317,313]	6	hSpCas9	negative selection	1044382
39709817	39709840	17	-	26627737	GBM cells	viability after 21 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.11376627855730681	[601]	[379,329]	1	hSpCas9	negative selection	1044383
39710088	39710111	17	+	26627737	GBM cells	viability after 21 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	1.1900369719705073	[187]	[243,222]	9	hSpCas9	negative selection	1044384
39700220	39700243	17	+	26627737	RPE1	viability after 9 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.05225852385558394	[2593]	[732,847]	0	hSpCas9	negative selection	1126693
39707049	39707072	17	+	26627737	RPE1	viability after 9 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.27116509370208797	[1001]	[262,255]	-2	hSpCas9	negative selection	1126694
39708439	39708462	17	-	26627737	RPE1	viability after 9 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	1.887526070528547	[673]	[678,911]	8	hSpCas9	negative selection	1126696
39709313	39709336	17	+	26627737	RPE1	viability after 9 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	1.1519440787829276	[810]	[537,597]	7	hSpCas9	negative selection	1126697
39709817	39709840	17	-	26627737	RPE1	viability after 9 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.3574514284332164	[1601]	[449,890]	2	hSpCas9	negative selection	1126698
39710088	39710111	17	+	26627737	RPE1	viability after 9 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.5570087942871974	[583]	[323,197]	4	hSpCas9	negative selection	1126699
39700220	39700243	17	+	26627737	RPE1	viability after 12 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.3165992003011706	[2593]	[511,609]	-2	hSpCas9	negative selection	1209008
39707049	39707072	17	+	26627737	RPE1	viability after 12 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.011550719886647076	[1001]	[285,246]	0	hSpCas9	negative selection	1209009
39708439	39708462	17	-	26627737	RPE1	viability after 12 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	1.3966606024306436	[673]	[417,538]	7	hSpCas9	negative selection	1209011
39709313	39709336	17	+	26627737	RPE1	viability after 12 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	1.0540995374264506	[810]	[347,562]	6	hSpCas9	negative selection	1209012
39709817	39709840	17	-	26627737	RPE1	viability after 12 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.6376702545422879	[1601]	[537,808]	4	hSpCas9	negative selection	1209013
39710088	39710111	17	+	26627737	RPE1	viability after 12 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.5822774924120916	[583]	[248,219]	4	hSpCas9	negative selection	1209014
39700220	39700243	17	+	26627737	RPE1	viability after 15 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.1685746495905751	[2593]	[547,753]	-1	hSpCas9	negative selection	1291323
39707049	39707072	17	+	26627737	RPE1	viability after 15 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.6491112285271088	[1001]	[166,193]	-4	hSpCas9	negative selection	1291324
39708439	39708462	17	-	26627737	RPE1	viability after 15 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	1.3408004469886077	[673]	[458,505]	7	hSpCas9	negative selection	1291326
39709313	39709336	17	+	26627737	RPE1	viability after 15 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	1.1753077825700633	[810]	[539,496]	6	hSpCas9	negative selection	1291327
39709817	39709840	17	-	26627737	RPE1	viability after 15 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.5930312252745598	[1601]	[735,632]	4	hSpCas9	negative selection	1291328
39710088	39710111	17	+	26627737	RPE1	viability after 15 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	-0.5226140170901581	[583]	[86,141]	-3	hSpCas9	negative selection	1291329
39700220	39700243	17	+	26627737	RPE1	viability after 18 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.32230454913763884	[2593]	[439,687]	-2	hSpCas9	negative selection	1373638
39707049	39707072	17	+	26627737	RPE1	viability after 18 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.18663317637399562	[1001]	[285,330]	1	hSpCas9	negative selection	1373639
39708439	39708462	17	-	26627737	RPE1	viability after 18 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	1.2210484359764893	[673]	[511,329]	7	hSpCas9	negative selection	1373641
39709313	39709336	17	+	26627737	RPE1	viability after 18 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	1.194681413139507	[810]	[397,610]	6	hSpCas9	negative selection	1373642
39709817	39709840	17	-	26627737	RPE1	viability after 18 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.6831760147793944	[1601]	[713,672]	4	hSpCas9	negative selection	1373643
39710088	39710111	17	+	26627737	RPE1	viability after 18 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	-1.0355024767346277	[583]	[58,95]	-6	hSpCas9	negative selection	1373644
39700220	39700243	17	+	26627737	HeLa	viability after 8 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	1.3800990971884632	[507]	[536,595,583]	8	hSpCas9	negative selection	1455953
39707049	39707072	17	+	26627737	HeLa	viability after 8 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.6582587290458664	[234]	[149,234,100]	5	hSpCas9	negative selection	1455954
39708439	39708462	17	-	26627737	HeLa	viability after 8 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.7454990431128766	[641]	[675,546,243]	6	hSpCas9	negative selection	1455956
39709313	39709336	17	+	26627737	HeLa	viability after 8 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.1296825260995762	[1056]	[486,266,514]	-1	hSpCas9	negative selection	1455957
39709817	39709840	17	-	26627737	HeLa	viability after 8 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.6343561274389358	[1094]	[377,169,382]	-6	hSpCas9	negative selection	1455958
39710088	39710111	17	+	26627737	HeLa	viability after 8 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	-0.6261244686581298	[385]	[106,123,95]	-6	hSpCas9	negative selection	1455959
39700220	39700243	17	+	26627737	HeLa	viability after 12 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	1.3532967895360108	[507]	[762,448,412]	8	hSpCas9	negative selection	1538268
39707049	39707072	17	+	26627737	HeLa	viability after 12 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.830655162705122	[234]	[169,182,163]	6	hSpCas9	negative selection	1538269
39708439	39708462	17	-	26627737	HeLa	viability after 12 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.155884267432425	[641]	[247,185,462]	1	hSpCas9	negative selection	1538271
39709313	39709336	17	+	26627737	HeLa	viability after 12 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.5993061261915701	[1056]	[346,294,223]	-5	hSpCas9	negative selection	1538272
39709817	39709840	17	-	26627737	HeLa	viability after 12 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-1.1234858097797442	[1094]	[144,115,369]	-8	hSpCas9	negative selection	1538273
39710088	39710111	17	+	26627737	HeLa	viability after 12 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.4638644422098961	[385]	[290,154,222]	4	hSpCas9	negative selection	1538274
39700220	39700243	17	+	26627737	HeLa	viability after 15 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	1.2847861044509927	[507]	[794,424,269]	8	hSpCas9	negative selection	1620583
39707049	39707072	17	+	26627737	HeLa	viability after 15 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.666048445291477	[234]	[184,141,125]	5	hSpCas9	negative selection	1620584
39708439	39708462	17	-	26627737	HeLa	viability after 15 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.8349264169540164	[641]	[453,499,442]	6	hSpCas9	negative selection	1620586
39709313	39709336	17	+	26627737	HeLa	viability after 15 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.5147423769410958	[1056]	[228,222,464]	-4	hSpCas9	negative selection	1620587
39709817	39709840	17	-	26627737	HeLa	viability after 15 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-1.2903240434978906	[1094]	[176,221,144]	-8	hSpCas9	negative selection	1620588
39710088	39710111	17	+	26627737	HeLa	viability after 15 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.384979805682409	[385]	[75,278,266]	3	hSpCas9	negative selection	1620589
39700220	39700243	17	+	26627737	HeLa	viability after 18 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	1.3102485409314741	[507]	[549,352,269]	8	hSpCas9	negative selection	1702898
39707049	39707072	17	+	26627737	HeLa	viability after 18 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.670961543398913	[234]	[127,113,125]	5	hSpCas9	negative selection	1702899
39708439	39708462	17	-	26627737	HeLa	viability after 18 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.8364694881216664	[641]	[307,410,442]	6	hSpCas9	negative selection	1702901
39709313	39709336	17	+	26627737	HeLa	viability after 18 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.5531013636425646	[1056]	[145,174,464]	-5	hSpCas9	negative selection	1702902
39709817	39709840	17	-	26627737	HeLa	viability after 18 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-1.2742125733046539	[1094]	[120,185,144]	-8	hSpCas9	negative selection	1702903
39710088	39710111	17	+	26627737	HeLa	viability after 18 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.39431509112207036	[385]	[47,237,266]	3	hSpCas9	negative selection	1702904
39700220	39700243	17	+	26627737	HCT116	viability after 6 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.7786806047090762	[1463]	[564,300]	4	hSpCas9	negative selection	1785213
39707049	39707072	17	+	26627737	HCT116	viability after 6 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	2.4282620240530006	[503]	[575,343]	9	hSpCas9	negative selection	1785214
39708439	39708462	17	-	26627737	HCT116	viability after 6 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.8974555222634519	[931]	[299,257]	5	hSpCas9	negative selection	1785216
39709313	39709336	17	+	26627737	HCT116	viability after 6 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.41154202407873275	[1460]	[376,59]	-2	hSpCas9	negative selection	1785217
39709817	39709840	17	-	26627737	HCT116	viability after 6 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.14630014088683618	[902]	[305,74]	0	hSpCas9	negative selection	1785218
39710088	39710111	17	+	26627737	HCT116	viability after 6 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.7155787550962188	[897]	[352,164]	4	hSpCas9	negative selection	1785219
39700220	39700243	17	+	26627737	HCT116	viability after 8 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.2370073311186509	[845]	[385,283,514]	-3	hSpCas9	negative selection	1867528
39707049	39707072	17	+	26627737	HCT116	viability after 8 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.47868812428445806	[481]	[236,175,159]	-5	hSpCas9	negative selection	1867529
39708439	39708462	17	-	26627737	HCT116	viability after 8 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.3381537558656281	[436]	[375,193,343]	3	hSpCas9	negative selection	1867531
39709313	39709336	17	+	26627737	HCT116	viability after 8 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.7580118001009464	[319]	[311,214,366]	7	hSpCas9	negative selection	1867532
39709817	39709840	17	-	26627737	HCT116	viability after 8 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.05895044161584362	[590]	[367,291,357]	0	hSpCas9	negative selection	1867533
39710088	39710111	17	+	26627737	HCT116	viability after 8 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.2374233147333027	[313]	[147,182,278]	2	hSpCas9	negative selection	1867534
39700220	39700243	17	+	26627737	HCT116	viability after 9 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.1760452600020761	[1463]	[630,291]	1	hSpCas9	negative selection	1949843
39707049	39707072	17	+	26627737	HCT116	viability after 9 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.2682817796903863	[503]	[270,75]	2	hSpCas9	negative selection	1949844
39708439	39708462	17	-	26627737	HCT116	viability after 9 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.4981290799005922	[931]	[322,373]	3	hSpCas9	negative selection	1949846
39709313	39709336	17	+	26627737	HCT116	viability after 9 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.5590306066887863	[1460]	[509,70]	-4	hSpCas9	negative selection	1949847
39709817	39709840	17	-	26627737	HCT116	viability after 9 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	1.136869131049131	[902]	[384,644]	7	hSpCas9	negative selection	1949848
39710088	39710111	17	+	26627737	HCT116	viability after 9 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.17219621201831814	[897]	[339,214]	1	hSpCas9	negative selection	1949849
39700220	39700243	17	+	26627737	HCT116	viability after 12 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.262551990606509	[845]	[238,476,409]	-3	hSpCas9	negative selection	2032158
39707049	39707072	17	+	26627737	HCT116	viability after 12 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.10254978907849333	[481]	[196,210,412]	1	hSpCas9	negative selection	2032159
39708439	39708462	17	-	26627737	HCT116	viability after 12 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.020594997502691892	[436]	[273,221,198]	0	hSpCas9	negative selection	2032161
39709313	39709336	17	+	26627737	HCT116	viability after 12 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.9679696310982712	[319]	[378,309,292]	8	hSpCas9	negative selection	2032162
39709817	39709840	17	-	26627737	HCT116	viability after 12 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.09028475278650605	[590]	[271,292,311]	-1	hSpCas9	negative selection	2032163
39710088	39710111	17	+	26627737	HCT116	viability after 12 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.5222172925040081	[313]	[212,233,265]	5	hSpCas9	negative selection	2032164
39700220	39700243	17	+	26627737	HCT116	viability after 15 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.6087029212046513	[845]	[457,294,220]	-6	hSpCas9	negative selection	2114473
39707049	39707072	17	+	26627737	HCT116	viability after 15 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.11533311485652897	[481]	[246,253,390]	1	hSpCas9	negative selection	2114474
39708439	39708462	17	-	26627737	HCT116	viability after 15 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.5568820791672691	[436]	[460,308,348]	5	hSpCas9	negative selection	2114476
39709313	39709336	17	+	26627737	HCT116	viability after 15 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.43398132756605173	[319]	[401,152,208]	4	hSpCas9	negative selection	2114477
39709817	39709840	17	-	26627737	HCT116	viability after 15 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.40401357789772285	[590]	[711,193,472]	4	hSpCas9	negative selection	2114478
39710088	39710111	17	+	26627737	HCT116	viability after 15 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.1864713647143174	[313]	[143,160,301]	2	hSpCas9	negative selection	2114479
39700220	39700243	17	+	26627737	HCT116	viability after 18 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-1.2783432234308991	[845]	[125,201,175]	-8	hSpCas9	negative selection	2196788
39707049	39707072	17	+	26627737	HCT116	viability after 18 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.11199395604706308	[481]	[273,198,172]	-1	hSpCas9	negative selection	2196789
39708439	39708462	17	-	26627737	HCT116	viability after 18 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.2406916465699518	[436]	[288,240,217]	2	hSpCas9	negative selection	2196791
39709313	39709336	17	+	26627737	HCT116	viability after 18 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.10355454733279454	[319]	[165,108,159]	-1	hSpCas9	negative selection	2196792
39709817	39709840	17	-	26627737	HCT116	viability after 18 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.19849194951197024	[590]	[357,311,313]	1	hSpCas9	negative selection	2196793
39710088	39710111	17	+	26627737	HCT116	viability after 18 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.7747968162710243	[313]	[86,160,550]	6	hSpCas9	negative selection	2196794
39706996	39707019	17	+	24336569	HL60	viability	CCGGCACAGACATGAAGCTGCGG	ERBB2	ENSG00000141736	-0.976558891036994	[1179]	[1268]	-7	hSpCas9	negative selection	2263082
39707021	39707044	17	-	24336569	HL60	viability	GGTGGGTCTCGGGACTGGCAGGG	ERBB2	ENSG00000141736	-0.2851926777003086	[447]	[777]	-3	hSpCas9	negative selection	2263083
39707026	39707049	17	-	24336569	HL60	viability	GTCCAGGTGGGTCTCGGGACTGG	ERBB2	ENSG00000141736	0.3232976001375807	[862]	[2284]	3	hSpCas9	negative selection	2263084
39707031	39707054	17	-	24336569	HL60	viability	AGCATGTCCAGGTGGGTCTCGGG	ERBB2	ENSG00000141736	1.0292393637773234	[325]	[1407]	7	hSpCas9	negative selection	2263085
39707038	39707061	17	-	24336569	HL60	viability	GTGGCGGAGCATGTCCAGGTGGG	ERBB2	ENSG00000141736	-0.7610215336306964	[582]	[727]	-6	hSpCas9	negative selection	2263086
39707048	39707071	17	+	24336569	HL60	viability	CATGCTCCGCCACCTCTACCAGG	ERBB2	ENSG00000141736	1.3645219869434495	[97]	[533]	8	hSpCas9	negative selection	2263087
39707054	39707077	17	-	24336569	HL60	viability	GGCAGCCCTGGTAGAGGTGGCGG	ERBB2	ENSG00000141736	0.29990859454097707	[774]	[2018]	3	hSpCas9	negative selection	2263088
39707060	39707083	17	+	24336569	HL60	viability	CCTCTACCAGGGCTGCCAGGTGG	ERBB2	ENSG00000141736	-0.274109178571292	[615]	[1077]	-2	hSpCas9	negative selection	2263089
39707066	39707089	17	+	24336569	HL60	viability	CCAGGGCTGCCAGGTGGTGCAGG	ERBB2	ENSG00000141736	0.7292508766100363	[918]	[3223]	6	hSpCas9	negative selection	2263090
39707075	39707098	17	+	24336569	HL60	viability	CCAGGTGGTGCAGGGAAACCTGG	ERBB2	ENSG00000141736	1.5062916149839403	[85]	[516]	8	hSpCas9	negative selection	2263091
39706996	39707019	17	+	24336569	KBM7	viability	CCGGCACAGACATGAAGCTGCGG	ERBB2	ENSG00000141736	-0.4466911109308793	[811]	[1624]	-4	hSpCas9	negative selection	2330259
39707021	39707044	17	-	24336569	KBM7	viability	GGTGGGTCTCGGGACTGGCAGGG	ERBB2	ENSG00000141736	1.1406510180061848	[146]	[883]	8	hSpCas9	negative selection	2330260
39707026	39707049	17	-	24336569	KBM7	viability	GTCCAGGTGGGTCTCGGGACTGG	ERBB2	ENSG00000141736	0.5258068108465428	[423]	[1664]	5	hSpCas9	negative selection	2330261
39707031	39707054	17	-	24336569	KBM7	viability	AGCATGTCCAGGTGGGTCTCGGG	ERBB2	ENSG00000141736	-0.36894194695943533	[597]	[1262]	-3	hSpCas9	negative selection	2330262
39707038	39707061	17	-	24336569	KBM7	viability	GTGGCGGAGCATGTCCAGGTGGG	ERBB2	ENSG00000141736	-1.6387769962817362	[426]	[373]	-8	hSpCas9	negative selection	2330263
39707048	39707071	17	+	24336569	KBM7	viability	CATGCTCCGCCACCTCTACCAGG	ERBB2	ENSG00000141736	2.348280086670892	[71]	[999]	9	hSpCas9	negative selection	2330264
39707054	39707077	17	-	24336569	KBM7	viability	GGCAGCCCTGGTAGAGGTGGCGG	ERBB2	ENSG00000141736	-1.0241323418315038	[726]	[974]	-6	hSpCas9	negative selection	2330265
39707060	39707083	17	+	24336569	KBM7	viability	CCTCTACCAGGGCTGCCAGGTGG	ERBB2	ENSG00000141736	0.023272598851557774	[468]	[1299]	0	hSpCas9	negative selection	2330266
39707066	39707089	17	+	24336569	KBM7	viability	CCAGGGCTGCCAGGTGGTGCAGG	ERBB2	ENSG00000141736	-0.38321763020838673	[1084]	[2268]	-3	hSpCas9	negative selection	2330267
39707075	39707098	17	+	24336569	KBM7	viability	CCAGGTGGTGCAGGGAAACCTGG	ERBB2	ENSG00000141736	0.9806578004848204	[101]	[548]	8	hSpCas9	negative selection	2330268
39689671	39689694	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGGCGGACGGATCACCTGAGG	ERBB2	ENSG00000141736	-0.024346393777309183	[3,58]	[5,7]	0	dCas9-VP64	positive selection	2394164
39698297	39698320	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAGTGCAGAGG	ERBB2	ENSG00000141736	-0.49998316673352905	[290,357]	[69,28]	-2	dCas9-VP64	positive selection	2425333
39687914	39687937	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTACGCAGTCGCGGTACACCGG	ERBB2	ENSG00000141736	1.512098697490846	[199,201]	[207,37]	5	dCas9-VP64	positive selection	2426583
39687933	39687956	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCCAGGGCGACCGTGAGCCGG	ERBB2	ENSG00000141736	-1.0454118592653627	[114,190]	[12,19]	-6	dCas9-VP64	positive selection	2426584
39688214	39688237	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGGAAGGCGGACGCCTGATGG	ERBB2	ENSG00000141736	0.4622913643764877	[59,65]	[33,2]	2	dCas9-VP64	positive selection	2427621
39688161	39688184	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGGGACGAGGGGCGGGGCAGG	ERBB2	ENSG00000141736	-1.5976342240098673	[0,50]	[0,1]	-8	dCas9-VP64	positive selection	2427622
39688188	39688211	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCCATATATCGAGGCGATAGG	ERBB2	ENSG00000141736	2.9083073506818637	[28,89]	[173,17]	8	dCas9-VP64	positive selection	2427623
39699864	39699887	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGTGCGTCCCTCCTAGCGCCGG	ERBB2	ENSG00000141736	1.6606200552964638	[8,103]	[12,67]	6	dCas9-VP64	positive selection	2435667
39699794	39699817	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCACCAGCCTCTGCATTTAGGG	ERBB2	ENSG00000141736	1.136671966573874	[198,175]	[75,105]	4	dCas9-VP64	positive selection	2435668
39699821	39699844	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCGAGGAAAAGTGTGAGAACGG	ERBB2	ENSG00000141736	5.202215734707286	[55,29]	[315,394]	9	dCas9-VP64	positive selection	2435669
39711467	39711490	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCATCGTGCCTGG	ERBB2	ENSG00000141736	-2.3680687732448105	[443,16]	[15,1]	-9	dCas9-VP64	positive selection	2440327
39692497	39692520	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGCAGAATCGCTTGAACCTGG	ERBB2	ENSG00000141736	4.376878119565056	[324,400]	[1478,1870]	9	dCas9-VP64	positive selection	2470923
39691339	39691362	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACCATCCTAGCCAACATGG	ERBB2	ENSG00000141736	0.13192249624084318	[146,169]	[41,33]	0	dCas9-VP64	positive selection	2475624
39689671	39689694	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGGCGGACGGATCACCTGAGG	ERBB2	ENSG00000141736	1.0571627137964825	[28,27]	[28,9]	6	dCas9-VP64	positive selection	2489419
39698297	39698320	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAGTGCAGAGG	ERBB2	ENSG00000141736	0.5593039216911941	[271,243]	[52,190]	4	dCas9-VP64	positive selection	2520588
39687914	39687937	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTACGCAGTCGCGGTACACCGG	ERBB2	ENSG00000141736	1.0277694444179355	[165,216]	[180,76]	6	dCas9-VP64	positive selection	2521838
39687933	39687956	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCCAGGGCGACCGTGAGCCGG	ERBB2	ENSG00000141736	-0.17235197219311948	[46,504]	[41,111]	-2	dCas9-VP64	positive selection	2521839
39688214	39688237	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGGAAGGCGGACGCCTGATGG	ERBB2	ENSG00000141736	-0.8139689498615048	[173,61]	[19,22]	-7	dCas9-VP64	positive selection	2522876
39688161	39688184	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGGGACGAGGGGCGGGGCAGG	ERBB2	ENSG00000141736	0.3584003591066889	[6,23]	[0,9]	3	dCas9-VP64	positive selection	2522877
39688188	39688211	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCCATATATCGAGGCGATAGG	ERBB2	ENSG00000141736	0.23238199692120298	[32,212]	[51,40]	1	dCas9-VP64	positive selection	2522878
39699864	39699887	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGTGCGTCCCTCCTAGCGCCGG	ERBB2	ENSG00000141736	3.918090317164417	[94,45]	[120,570]	9	dCas9-VP64	positive selection	2530922
39699794	39699817	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCACCAGCCTCTGCATTTAGGG	ERBB2	ENSG00000141736	0.6477938754308414	[98,71]	[28,57]	5	dCas9-VP64	positive selection	2530923
39699821	39699844	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCGAGGAAAAGTGTGAGAACGG	ERBB2	ENSG00000141736	1.5877114416995863	[143,47]	[182,13]	8	dCas9-VP64	positive selection	2530924
39711467	39711490	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCATCGTGCCTGG	ERBB2	ENSG00000141736	0.42142368151358683	[69,54]	[32,21]	3	dCas9-VP64	positive selection	2535582
39692497	39692520	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGCAGAATCGCTTGAACCTGG	ERBB2	ENSG00000141736	2.6681151119317885	[136,149]	[134,451]	9	dCas9-VP64	positive selection	2566178
39691339	39691362	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACCATCCTAGCCAACATGG	ERBB2	ENSG00000141736	1.169571951725572	[51,120]	[60,65]	7	dCas9-VP64	positive selection	2570879
39687930	39687953	17	+	27013184	SW480	treatment with recombinant TRAIL	ACACCGGCTCACGGTCGCCCTGG	ERBB2	ENSG00000141736	0.3190630611935775	[193,174]	[15,218]	1	hSpCas9	positive selection	2961048
39687921	39687944	17	+	27013184	SW480	treatment with recombinant TRAIL	AGTCGCGGTACACCGGCTCACGG	ERBB2	ENSG00000141736	-4.206127572326697	[85,84]	[1,1]	-9	hSpCas9	positive selection	2961049
39707024	39707047	17	+	27013184	SW480	treatment with recombinant TRAIL	TGCCAGTCCCGAGACCCACCTGG	ERBB2	ENSG00000141736	0.7462075368593629	[159,272]	[143,165]	3	hSpCas9	positive selection	2961050
39707048	39707071	17	+	27013184	SW480	treatment with recombinant TRAIL	CATGCTCCGCCACCTCTACCAGG	ERBB2	ENSG00000141736	-0.052943528237638704	[658,678]	[260,301]	0	hSpCas9	positive selection	2961051
39707049	39707072	17	+	27013184	SW480	treatment with recombinant TRAIL	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.2844525242401996	[532,469]	[139,442]	1	hSpCas9	positive selection	2961052
39707057	39707080	17	+	27013184	SW480	treatment with recombinant TRAIL	CCACCTCTACCAGGGCTGCCAGG	ERBB2	ENSG00000141736	-2.591857723879851	[107,235]	[1,25]	-8	hSpCas9	positive selection	2961053
39707060	39707083	17	+	27013184	SW480	treatment with recombinant TRAIL	CCTCTACCAGGGCTGCCAGGTGG	ERBB2	ENSG00000141736	-0.38368164422701884	[224,383]	[59,152]	-2	hSpCas9	positive selection	2961054
39707067	39707090	17	+	27013184	SW480	treatment with recombinant TRAIL	CAGGGCTGCCAGGTGGTGCAGGG	ERBB2	ENSG00000141736	0.16372774720874517	[321,385]	[73,305]	0	hSpCas9	positive selection	2961055
39706986	39707009	17	-	27013184	SW480	treatment with recombinant TRAIL	ATGTCTGTGCCGGTGCACACTGG	ERBB2	ENSG00000141736	2.5227359943086762	[62,31]	[133,102]	9	hSpCas9	positive selection	2961056
39707022	39707045	17	-	27013184	SW480	treatment with recombinant TRAIL	AGGTGGGTCTCGGGACTGGCAGG	ERBB2	ENSG00000141736	0.3056161014636685	[261,318]	[75,263]	1	hSpCas9	positive selection	2961057
39707031	39707054	17	-	27013184	SW480	treatment with recombinant TRAIL	AGCATGTCCAGGTGGGTCTCGGG	ERBB2	ENSG00000141736	-0.5348112815684254	[459,801]	[201,156]	-2	hSpCas9	positive selection	2961058
39707032	39707055	17	-	27013184	SW480	treatment with recombinant TRAIL	GAGCATGTCCAGGTGGGTCTCGG	ERBB2	ENSG00000141736	1.212922662780669	[516,718]	[354,970]	6	hSpCas9	positive selection	2961059
39707038	39707061	17	-	27013184	SW480	treatment with recombinant TRAIL	GTGGCGGAGCATGTCCAGGTGGG	ERBB2	ENSG00000141736	0.965884106874793	[607,814]	[579,608]	4	hSpCas9	positive selection	2961060
39707039	39707062	17	-	27013184	SW480	treatment with recombinant TRAIL	GGTGGCGGAGCATGTCCAGGTGG	ERBB2	ENSG00000141736	-0.019560193515162916	[401,334]	[224,62]	0	hSpCas9	positive selection	2961061
39707042	39707065	17	-	27013184	SW480	treatment with recombinant TRAIL	AGAGGTGGCGGAGCATGTCCAGG	ERBB2	ENSG00000141736	-2.904175617203208	[238,180]	[3,23]	-8	hSpCas9	positive selection	2961062
39707054	39707077	17	-	27013184	SW480	treatment with recombinant TRAIL	GGCAGCCCTGGTAGAGGTGGCGG	ERBB2	ENSG00000141736	-0.7165472749973234	[272,230]	[83,41]	-3	hSpCas9	positive selection	2961063
39707057	39707080	17	-	27013184	SW480	treatment with recombinant TRAIL	CCTGGCAGCCCTGGTAGAGGTGG	ERBB2	ENSG00000141736	-4.121425912534015	[312,166]	[8,1]	-9	hSpCas9	positive selection	2961064
39707060	39707083	17	-	27013184	SW480	treatment with recombinant TRAIL	CCACCTGGCAGCCCTGGTAGAGG	ERBB2	ENSG00000141736	-0.16806426844857494	[131,256]	[79,61]	0	hSpCas9	positive selection	2961065
39700226	39700249	17	+	27013184	SW480	treatment with recombinant TRAIL	CGCAGTGAGCACCATGGAGCTGG	ERBB2	ENSG00000141736	-0.38204253133317545	[481,548]	[113,248]	-2	hSpCas9	positive selection	2961066
39707066	39707089	17	-	27013184	SW480	treatment with recombinant TRAIL	CCTGCACCACCTGGCAGCCCTGG	ERBB2	ENSG00000141736	-0.6307479191764419	[386,279]	[78,115]	-3	hSpCas9	positive selection	2961067
39707075	39707098	17	-	27013184	SW480	treatment with recombinant TRAIL	CCAGGTTTCCCTGCACCACCTGG	ERBB2	ENSG00000141736	0.9858547328853431	[640,616]	[691,319]	5	hSpCas9	positive selection	2961068
39707093	39707116	17	-	27013184	SW480	treatment with recombinant TRAIL	TGGGCAGGTAGGTGAGTTCCAGG	ERBB2	ENSG00000141736	1.5978151216654666	[620,878]	[1085,791]	7	hSpCas9	positive selection	2961069
39707104	39707127	17	-	27013184	SW480	treatment with recombinant TRAIL	GCTGGCATTGGTGGGCAGGTAGG	ERBB2	ENSG00000141736	1.5818768468578934	[176,150]	[214,210]	7	hSpCas9	positive selection	2961070
39707108	39707131	17	-	27013184	SW480	treatment with recombinant TRAIL	ACAGGCTGGCATTGGTGGGCAGG	ERBB2	ENSG00000141736	1.4406870537979528	[306,549]	[407,604]	6	hSpCas9	positive selection	2961071
39707112	39707135	17	-	27013184	SW480	treatment with recombinant TRAIL	AAGGACAGGCTGGCATTGGTGGG	ERBB2	ENSG00000141736	-0.6422653250035852	[93,145]	[53,1]	-3	hSpCas9	positive selection	2961072
39707116	39707139	17	-	27013184	SW480	treatment with recombinant TRAIL	CAGGAAGGACAGGCTGGCATTGG	ERBB2	ENSG00000141736	1.0698217466038467	[276,243]	[259,204]	5	hSpCas9	positive selection	2961073
39707135	39707158	17	-	27013184	SW480	treatment with recombinant TRAIL	TGCCCACGGGCCTCACCTGCAGG	ERBB2	ENSG00000141736	0.8813556401410036	[264,205]	[218,146]	4	hSpCas9	positive selection	2961074
39700299	39700322	17	+	27013184	SW480	treatment with recombinant TRAIL	GCGAGCACCCAAGGTGGGTCTGG	ERBB2	ENSG00000141736	0.19799607421524423	[225,235]	[83,156]	1	hSpCas9	positive selection	2961075
39700304	39700327	17	+	27013184	SW480	treatment with recombinant TRAIL	CACCCAAGGTGGGTCTGGTGTGG	ERBB2	ENSG00000141736	1.3626552369306304	[360,618]	[353,782]	6	hSpCas9	positive selection	2961076
39700305	39700328	17	+	27013184	SW480	treatment with recombinant TRAIL	ACCCAAGGTGGGTCTGGTGTGGG	ERBB2	ENSG00000141736	0.10885747057592865	[334,664]	[236,209]	0	hSpCas9	positive selection	2961077
39715500	39715523	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGAACCTGCAAGTAATCCGGGG	ERBB2	ENSG00000141736	-0.06625325367014517	[3,2]	[2,2]	-1	hSpCas9	positive selection	2986203
39709817	39709840	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.6064781817012574	[3,3]	[1,1]	-7	hSpCas9	positive selection	2986204
39709409	39709432	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATCAGTGTGAGAGCCAGCTGG	ERBB2	ENSG00000141736	0.5673310289775004	[3,2]	[2,4]	9	hSpCas9	positive selection	2986205
39710419	39710442	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	0.13716311786541693	[3,3]	[2,3]	3	hSpCas9	positive selection	2986206
39715500	39715523	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGAACCTGCAAGTAATCCGGGG	ERBB2	ENSG00000141736	0.44331655589377467	[3,3]	[2,3]	7	hSpCas9	positive selection	3054061
39709817	39709840	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.1495413718569082	[3,3]	[1,1]	-2	hSpCas9	positive selection	3054062
39709409	39709432	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATCAGTGTGAGAGCCAGCTGG	ERBB2	ENSG00000141736	0.2814946465049407	[3,3]	[3,1]	5	hSpCas9	positive selection	3054063
39710419	39710442	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.46491893245442634	[3,3]	[2,0]	-6	hSpCas9	positive selection	3054064
39712365	39712388		+	24336571	A375	resistance to PLX after 7 days	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.3709808200674827	[17,17]	[12,14]	-9	hSpCas9	positive selection	3112372
39711923	39711946		+	24336571	A375	resistance to PLX after 7 days	CTTAGACAACTACCTTTCTACGG	ERBB2	ENSG00000141736	-0.4845617925550695	[15,17]	[11,11]	-9	hSpCas9	positive selection	3112373
39712426	39712449		+	24336571	A375	resistance to PLX after 7 days	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	-0.04805308693458252	[13,15]	[14,12]	-1	hSpCas9	positive selection	3112374
39712365	39712388		+	24336571	A375	resistance to PLX after 14 days	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.6955306076578155	[25,14]	[5,4]	-7	hSpCas9	positive selection	3170165
39711923	39711946		+	24336571	A375	resistance to PLX after 14 days	CTTAGACAACTACCTTTCTACGG	ERBB2	ENSG00000141736	-0.8431046881094113	[12,11]	[2,2]	-8	hSpCas9	positive selection	3170166
39712426	39712449		+	24336571	A375	resistance to PLX after 14 days	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	-0.15348245293186547	[8,14]	[4,3]	-2	hSpCas9	positive selection	3170167
39712365	39712388		+	24336571	A375	viability after 7 days	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.4431832880838069	[25]	[17,17]	-6	hSpCas9	negative selection	3227958
39711923	39711946		+	24336571	A375	viability after 7 days	CTTAGACAACTACCTTTCTACGG	ERBB2	ENSG00000141736	-0.3589727650849699	[22]	[15,17]	-5	hSpCas9	negative selection	3227959
39712426	39712449		+	24336571	A375	viability after 7 days	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	-0.10384562965585475	[16]	[13,15]	-1	hSpCas9	negative selection	3227960
39712365	39712388		+	24336571	A375	viability after 14 days	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.26533803354733554	[25]	[25,14]	-3	hSpCas9	negative selection	3285751
39711923	39711946		+	24336571	A375	viability after 14 days	CTTAGACAACTACCTTTCTACGG	ERBB2	ENSG00000141736	-0.7619516291022425	[22]	[12,11]	-7	hSpCas9	negative selection	3285752
39712426	39712449		+	24336571	A375	viability after 14 days	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	-0.3849874528094407	[16]	[8,14]	-4	hSpCas9	negative selection	3285753
39715516	39715539	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	1.50401112910112	[44,62]	[0,0]	6	hSpCas9	positive selection	3348242
39712036	39712059	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	1.1269659534271936	[77,61]	[0,0]	5	hSpCas9	positive selection	3348243
39715450	39715473	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.18512791407374643	[144,123]	[0,0]	1	hSpCas9	positive selection	3348244
39712365	39712388	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.9275491314624489	[290,290]	[0,0]	-6	hSpCas9	positive selection	3367453
39712426	39712449	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	-0.17730201619088934	[172,172]	[0,0]	-1	hSpCas9	positive selection	3367454
39711968	39711991	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	-1.0510128186935723	[316,316]	[0,0]	-7	hSpCas9	positive selection	3367455
39715499	39715522	17	+	26780180	HT29	viability (Avana library 4 designs)	CAGAACCTGCAAGTAATCCGGGG	ERBB2	ENSG00000141736	2.66617619057751	[]	[]	8	hSpCas9	negative selection	3423026
39709817	39709840	17	-	26780180	HT29	viability (Avana library 4 designs)	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	2.4475185760717	[]	[]	8	hSpCas9	negative selection	3423027
39709409	39709432	17	-	26780180	HT29	viability (Avana library 4 designs)	CTATCAGTGTGAGAGCCAGCTGG	ERBB2	ENSG00000141736	3.07055663889146	[]	[]	8	hSpCas9	negative selection	3423028
39710418	39710441	17	+	26780180	HT29	viability (Avana library 4 designs)	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	3.06561003586289	[]	[]	8	hSpCas9	negative selection	3423029
39710418	39710441	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-2.8546537358084	[]	[]	-3	hSpCas9	negative selection	3503977
39715499	39715522	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAACCTGCAAGTAATCCGGGG	ERBB2	ENSG00000141736	-0.404470655715237	[]	[]	0	hSpCas9	negative selection	3503978
39709409	39709432	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTATCAGTGTGAGAGCCAGCTGG	ERBB2	ENSG00000141736	3.02928423692623	[]	[]	4	hSpCas9	negative selection	3503979
39709817	39709840	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-7.27187270242678	[]	[]	-6	hSpCas9	negative selection	3503980
39708311	39708334	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCCCTCCCAGGATATCCAGGAGG	ERBB2	ENSG00000141736	-2.65344471982239	[]	[]	-3	hSpCas9	negative selection	3503981
39719788	39719811	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGTGGACCTGGATGACAAGGG	ERBB2	ENSG00000141736	-0.474974219395208	[]	[]	0	hSpCas9	negative selection	3503982
39710418	39710441	17	+	26780180	A375	viability (Avana lentiGuide)	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	3.42569281321683	[]	[]	3	hSpCas9	negative selection	3612636
39715499	39715522	17	+	26780180	A375	viability (Avana lentiGuide)	CAGAACCTGCAAGTAATCCGGGG	ERBB2	ENSG00000141736	0.125946673893308	[]	[]	0	hSpCas9	negative selection	3612637
39709409	39709432	17	-	26780180	A375	viability (Avana lentiGuide)	CTATCAGTGTGAGAGCCAGCTGG	ERBB2	ENSG00000141736	-0.264010099136141	[]	[]	0	hSpCas9	negative selection	3612638
39709817	39709840	17	-	26780180	A375	viability (Avana lentiGuide)	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	4.33534590847463	[]	[]	4	hSpCas9	negative selection	3612639
39708311	39708334	17	+	26780180	A375	viability (Avana lentiGuide)	CCCCTCCCAGGATATCCAGGAGG	ERBB2	ENSG00000141736	7.53957627479352	[]	[]	6	hSpCas9	negative selection	3612640
39719788	39719811	17	+	26780180	A375	viability (Avana lentiGuide)	TGTGTGGACCTGGATGACAAGGG	ERBB2	ENSG00000141736	5.22373076030389	[]	[]	4	hSpCas9	negative selection	3612641
39710418	39710441	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.8346935478833855	[5]	[2,1]	-8	hSpCas9	positive selection	3721295
39715499	39715522	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAACCTGCAAGTAATCCGGGG	ERBB2	ENSG00000141736	-0.5243293018201387	[4]	[3,2]	-6	hSpCas9	positive selection	3721296
39709409	39709432	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATCAGTGTGAGAGCCAGCTGG	ERBB2	ENSG00000141736	-0.2546373482758581	[4]	[3,2]	-4	hSpCas9	positive selection	3721297
39709817	39709840	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.5639790266159274	[4]	[3,2]	-7	hSpCas9	positive selection	3721298
39708311	39708334	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCCTCCCAGGATATCCAGGAGG	ERBB2	ENSG00000141736	-0.5369783678303586	[3]	[1,2]	-7	hSpCas9	positive selection	3721299
39719788	39719811	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGTGGACCTGGATGACAAGGG	ERBB2	ENSG00000141736	-0.23364160877902768	[5]	[4,3]	-4	hSpCas9	positive selection	3721300
39710418	39710441	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.2414832807728065	[5]	[4,2]	-3	hSpCas9	positive selection	3829902
39715499	39715522	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAACCTGCAAGTAATCCGGGG	ERBB2	ENSG00000141736	-0.435145564881276	[5]	[3,2]	-5	hSpCas9	positive selection	3829903
39709409	39709432	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATCAGTGTGAGAGCCAGCTGG	ERBB2	ENSG00000141736	-0.15559139296218866	[4]	[4,2]	-2	hSpCas9	positive selection	3829904
39709817	39709840	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-1.0641013442891705	[5]	[1,2]	-8	hSpCas9	positive selection	3829905
39708311	39708334	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCCTCCCAGGATATCCAGGAGG	ERBB2	ENSG00000141736	-1.0803859540665575	[4]	[1,0]	-8	hSpCas9	positive selection	3829906
39719788	39719811	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGTGGACCTGGATGACAAGGG	ERBB2	ENSG00000141736	-0.6573395303539779	[5]	[4,0]	-7	hSpCas9	positive selection	3829907
39715516	39715539	17	-	26780180	A375	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	1.30252031999171	[]	[]	7	hSpCas9	negative selection	3937257
39712365	39712388	17	+	26780180	A375	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	1.60752446004039	[]	[]	8	hSpCas9	negative selection	3937258
39715450	39715473	17	-	26780180	A375	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.948051167898976	[]	[]	4	hSpCas9	negative selection	3937259
39711968	39711991	17	+	26780180	A375	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.608148875092525	[]	[]	2	hSpCas9	negative selection	3937260
39712036	39712059	17	-	26780180	A375	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	1.3574058269188	[]	[]	7	hSpCas9	negative selection	3937261
39712426	39712449	17	+	26780180	A375	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.32828898230563	[]	[]	0	hSpCas9	negative selection	3937262
39715516	39715539	17	-	26780180	HT29	viability (GeCKOv2 library)	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	1.5621402943004	[]	[]	8	hSpCas9	negative selection	4045223
39712365	39712388	17	+	26780180	HT29	viability (GeCKOv2 library)	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	2.14396910263379	[]	[]	9	hSpCas9	negative selection	4045224
39715450	39715473	17	-	26780180	HT29	viability (GeCKOv2 library)	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	1.06899312944106	[]	[]	5	hSpCas9	negative selection	4045225
39711968	39711991	17	+	26780180	HT29	viability (GeCKOv2 library)	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	1.00535482170751	[]	[]	4	hSpCas9	negative selection	4045226
39712036	39712059	17	-	26780180	HT29	viability (GeCKOv2 library)	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	1.53650119615465	[]	[]	7	hSpCas9	negative selection	4045227
39712426	39712449	17	+	26780180	HT29	viability (GeCKOv2 library)	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.410790982651556	[]	[]	1	hSpCas9	negative selection	4045228
39712365	39712388	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.35477233383981044	[4]	[1,2]	-7	hSpCas9	positive selection	4135097
39711923	39711946	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTAGACAACTACCTTTCTACGG	ERBB2	ENSG00000141736	-0.41873322786971784	[3]	[1,1]	-8	hSpCas9	positive selection	4135098
39712426	39712449	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	-0.22042250612273304	[4]	[2,2]	-5	hSpCas9	positive selection	4135099
39712365	39712388	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.28251090344884267	[4]	[0,3,2,0]	-4	hSpCas9	positive selection	4199119
39711923	39711946	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTAGACAACTACCTTTCTACGG	ERBB2	ENSG00000141736	-0.17763769687396513	[4]	[3,0,3,0]	-3	hSpCas9	positive selection	4199120
39712426	39712449	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.094989428579568	[3]	[2,3,1,0]	0	hSpCas9	positive selection	4199121
39715516	39715539	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.868450089628219	[1]	[0,0]	-9	hSpCas9	positive selection	4269102
39712036	39712059	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.2933554908415848	[2]	[1,2]	6	hSpCas9	positive selection	4269103
39715450	39715473	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.2970115124016399	[3]	[2,1]	-6	hSpCas9	positive selection	4269104
39712365	39712388	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.6803205116658722	[3]	[2,0]	-9	hSpCas9	positive selection	4333367
39712426	39712449	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	-0.1690733961771051	[3]	[3,0]	-3	hSpCas9	positive selection	4333368
39711968	39711991	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.058073489869217065	[3]	[3,2]	1	hSpCas9	positive selection	4333369
39715852	39715874	17	+	27760321	OCIAML3	viability	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	0.43077818154017367	[793,721]	[660,977]	5	hSpCas9	negative selection	4398173
39715919	39715941	17	+	27760321	OCIAML3	viability	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-0.11779925479202205	[514,457]	[396,288]	-1	hSpCas9	negative selection	4398174
39709435	39709457	17	-	27760321	OCIAML3	viability	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	0.030403552743263784	[1261,962]	[757,1042]	0	hSpCas9	negative selection	4398175
39710433	39710455	17	-	27760321	OCIAML3	viability	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-0.7398813949564307	[946,745]	[303,510]	-6	hSpCas9	negative selection	4398176
39711935	39711957	17	-	27760321	OCIAML3	viability	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	0.7458682106532749	[399,312]	[453,477]	8	hSpCas9	negative selection	4398177
39715852	39715874	17	+	27760321	OCIAML2	viability	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-0.3151320357293824	[793,721]	[492,491]	-4	hSpCas9	negative selection	4481636
39715919	39715941	17	+	27760321	OCIAML2	viability	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	0.2693536295348966	[514,457]	[382,592]	3	hSpCas9	negative selection	4481637
39709435	39709457	17	-	27760321	OCIAML2	viability	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-0.03767774365536014	[1261,962]	[664,1139]	0	hSpCas9	negative selection	4481638
39710433	39710455	17	-	27760321	OCIAML2	viability	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-0.4632953207254293	[946,745]	[505,476]	-5	hSpCas9	negative selection	4481639
39711935	39711957	17	-	27760321	OCIAML2	viability	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-0.06229215563819951	[399,312]	[285,258]	-1	hSpCas9	negative selection	4481640
39715852	39715874	17	+	27760321	MV411	viability	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	0.0026767200384777423	[793,721]	[290,815]	0	hSpCas9	negative selection	4565099
39715919	39715941	17	+	27760321	MV411	viability	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	0.2766864886130407	[514,457]	[291,532]	2	hSpCas9	negative selection	4565100
39709435	39709457	17	-	27760321	MV411	viability	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	0.8509547752243847	[1261,962]	[1199,1484]	6	hSpCas9	negative selection	4565101
39710433	39710455	17	-	27760321	MV411	viability	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-0.8978010845130393	[946,745]	[139,534]	-6	hSpCas9	negative selection	4565102
39711935	39711957	17	-	27760321	MV411	viability	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-0.12118791584539662	[399,312]	[26,496]	-1	hSpCas9	negative selection	4565103
39715852	39715874	17	+	27760321	HL60	viability	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	0.9866454733997345	[793,721]	[984,1481]	9	hSpCas9	negative selection	4648562
39715919	39715941	17	+	27760321	HL60	viability	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	0.017278230332948646	[514,457]	[420,380]	0	hSpCas9	negative selection	4648563
39709435	39709457	17	-	27760321	HL60	viability	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	0.323214936106744	[1261,962]	[901,1367]	4	hSpCas9	negative selection	4648564
39710433	39710455	17	-	27760321	HL60	viability	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-0.4488790070538241	[946,745]	[430,579]	-5	hSpCas9	negative selection	4648565
39711935	39711957	17	-	27760321	HL60	viability	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	0.660598543342862	[399,312]	[431,483]	7	hSpCas9	negative selection	4648566
39715852	39715874	17	+	27760321	HT1080	viability	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	0.4950285026960921	[721,563]	[466,244]	2	hSpCas9	negative selection	4732025
39715919	39715941	17	+	27760321	HT1080	viability	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-1.276481675744008	[457,357]	[5,133]	-5	hSpCas9	negative selection	4732026
39709435	39709457	17	-	27760321	HT1080	viability	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-0.36355275482300875	[962,751]	[286,241]	-2	hSpCas9	negative selection	4732027
39710433	39710455	17	-	27760321	HT1080	viability	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	0.22149077452501564	[745,581]	[200,425]	1	hSpCas9	negative selection	4732028
39711935	39711957	17	-	27760321	HT1080	viability	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	2.91622814338887	[312,243]	[1067,584]	9	hSpCas9	negative selection	4732029
39715852	39715874	17	+	27760321	HT29	viability after 7 days	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-0.3434222651729202	[721,563]	[846,616,521]	-5	hSpCas9	negative selection	4815488
39715919	39715941	17	+	27760321	HT29	viability after 7 days	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	0.10274286229246174	[457,357]	[643,565,492]	1	hSpCas9	negative selection	4815489
39709435	39709457	17	-	27760321	HT29	viability after 7 days	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-0.17636044298314135	[962,751]	[1148,942,861]	-3	hSpCas9	negative selection	4815490
39710433	39710455	17	-	27760321	HT29	viability after 7 days	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-0.8508079845989758	[745,581]	[617,348,472]	-8	hSpCas9	negative selection	4815491
39711935	39711957	17	-	27760321	HT29	viability after 7 days	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-0.33027132735016246	[312,243]	[193,266,376]	-5	hSpCas9	negative selection	4815492
39715852	39715874	17	+	27760321	HT29	viability after 25 days	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-1.889894358640125	[721,563]	[217,153,223]	-8	hSpCas9	negative selection	4898951
39715919	39715941	17	+	27760321	HT29	viability after 25 days	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-2.1215709643698526	[457,357]	[74,100,151]	-8	hSpCas9	negative selection	4898952
39709435	39709457	17	-	27760321	HT29	viability after 25 days	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-1.7740410364938644	[962,751]	[275,252,335]	-8	hSpCas9	negative selection	4898953
39710433	39710455	17	-	27760321	HT29	viability after 25 days	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-2.1573528709684204	[745,581]	[173,163,171]	-8	hSpCas9	negative selection	4898954
39711935	39711957	17	-	27760321	HT29	viability after 25 days	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-1.333357176064109	[312,243]	[118,117,143]	-7	hSpCas9	negative selection	4898955
39715852	39715874	17	+	27760321	HT29	viability after 22 days	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-1.1378530000191507	[721,563]	[614,256,131]	-7	hSpCas9	negative selection	4982414
39715919	39715941	17	+	27760321	HT29	viability after 22 days	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-1.1533240649272547	[457,357]	[107,217,313]	-7	hSpCas9	negative selection	4982415
39709435	39709457	17	-	27760321	HT29	viability after 22 days	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-1.8050802544431348	[962,751]	[349,242,255]	-8	hSpCas9	negative selection	4982416
39710433	39710455	17	-	27760321	HT29	viability after 22 days	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-2.046268988634225	[745,581]	[120,280,156]	-8	hSpCas9	negative selection	4982417
39711935	39711957	17	-	27760321	HT29	viability after 22 days	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-0.8750475606981347	[312,243]	[178,118,228]	-6	hSpCas9	negative selection	4982418
39715852	39715874	17	+	27760321	HT29	viability after 19 days	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-2.3695903383408794	[721,563]	[300,68,75]	-8	hSpCas9	negative selection	5065877
39715919	39715941	17	+	27760321	HT29	viability after 19 days	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-1.2332167936507732	[457,357]	[105,74,396]	-7	hSpCas9	negative selection	5065878
39709435	39709457	17	-	27760321	HT29	viability after 19 days	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-0.9469071799815361	[962,751]	[437,745,340]	-6	hSpCas9	negative selection	5065879
39710433	39710455	17	-	27760321	HT29	viability after 19 days	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-1.7865982280198354	[745,581]	[204,270,183]	-8	hSpCas9	negative selection	5065880
39711935	39711957	17	-	27760321	HT29	viability after 19 days	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-2.0173026854539002	[312,243]	[79,20,132]	-8	hSpCas9	negative selection	5065881
39715852	39715874	17	+	27760321	HT29	viability after 16 days	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-1.8865375689614905	[721,563]	[239,78,271]	-8	hSpCas9	negative selection	5149340
39715919	39715941	17	+	27760321	HT29	viability after 16 days	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-0.7181392694126687	[457,357]	[219,125,484]	-6	hSpCas9	negative selection	5149341
39709435	39709457	17	-	27760321	HT29	viability after 16 days	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-0.7736678419217003	[962,751]	[702,440,555]	-6	hSpCas9	negative selection	5149342
39710433	39710455	17	-	27760321	HT29	viability after 16 days	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-1.9251064632275727	[745,581]	[238,191,159]	-8	hSpCas9	negative selection	5149343
39711935	39711957	17	-	27760321	HT29	viability after 16 days	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-0.5078155837453295	[312,243]	[271,192,197]	-5	hSpCas9	negative selection	5149344
39715852	39715874	17	+	27760321	HT29	viability after 13 days	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-1.3854044224848872	[721,563]	[268,205,375]	-8	hSpCas9	negative selection	5232803
39715919	39715941	17	+	27760321	HT29	viability after 13 days	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-0.48850149556689015	[457,357]	[353,301,354]	-5	hSpCas9	negative selection	5232804
39709435	39709457	17	-	27760321	HT29	viability after 13 days	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-1.0678956770805172	[962,751]	[452,536,435]	-7	hSpCas9	negative selection	5232805
39710433	39710455	17	-	27760321	HT29	viability after 13 days	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-1.1519909034854525	[745,581]	[399,297,341]	-7	hSpCas9	negative selection	5232806
39711935	39711957	17	-	27760321	HT29	viability after 13 days	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	-1.0029948637736388	[312,243]	[87,221,172]	-7	hSpCas9	negative selection	5232807
39715852	39715874	17	+	27760321	HT29	viability after 10 days	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-0.8949863594245298	[721,563]	[459,435,399]	-7	hSpCas9	negative selection	5316266
39715919	39715941	17	+	27760321	HT29	viability after 10 days	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-0.47051705637531227	[457,357]	[342,298,456]	-5	hSpCas9	negative selection	5316267
39709435	39709457	17	-	27760321	HT29	viability after 10 days	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-0.40536122587371914	[962,751]	[933,1030,473]	-5	hSpCas9	negative selection	5316268
39710433	39710455	17	-	27760321	HT29	viability after 10 days	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	-1.0685817072395687	[745,581]	[398,438,349]	-8	hSpCas9	negative selection	5316269
39711935	39711957	17	-	27760321	HT29	viability after 10 days	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	0.1230274369896194	[312,243]	[154,460,518]	1	hSpCas9	negative selection	5316270
39715852	39715874	17	+	27760321	MOLM13	viability	TTCGTGCACACGGTGCCCTGGG	ERBB2	ENSG00000141736	-0.6866454825193499	[793,721]	[264,265]	-4	hSpCas9	negative selection	5399729
39715919	39715941	17	+	27760321	MOLM13	viability	ACCGGCCAGAGGACGAGTGTGG	ERBB2	ENSG00000141736	-0.7220637433305608	[514,457]	[217,121]	-4	hSpCas9	negative selection	5399730
39709435	39709457	17	-	27760321	MOLM13	viability	TTACAGGCCCGAGAGCGGTTGG	ERBB2	ENSG00000141736	-0.21228688779632132	[1261,962]	[791,320]	-1	hSpCas9	negative selection	5399731
39710433	39710455	17	-	27760321	MOLM13	viability	CGAATGTATACCGGCCCTCGGG	ERBB2	ENSG00000141736	0.28866138364898464	[946,745]	[678,494]	2	hSpCas9	negative selection	5399732
39711935	39711957	17	-	27760321	MOLM13	viability	GGATCCCACGTCCGTAGAAAGG	ERBB2	ENSG00000141736	0.8365448643389584	[399,312]	[211,479]	6	hSpCas9	negative selection	5399733
39700432	39700455	17	+	27661255	K562	viability	GTGGACAGTCGAGACGCTCAGGG	ERBB2	ENSG00000141736	0.47729731209503656	[360,473]	[542,392]	9	dCas9-KRAB	negative selection	5477689
39700477	39700500	17	+	27661255	K562	viability	GGCGGGAGGGGGCAGTTACACGG	ERBB2	ENSG00000141736	0.43775132266187056	[797,841]	[928,849]	9	dCas9-KRAB	negative selection	5477690
39700115	39700138	17	-	27661255	K562	viability	GTAAAGGGCCCCGTGGGAAGGGG	ERBB2	ENSG00000141736	-0.09197278093742822	[3319,3533]	[2720,2432]	-3	dCas9-KRAB	negative selection	5477691
39700121	39700144	17	-	27661255	K562	viability	GGCGCAGTAAAGGGCCCCGTGGG	ERBB2	ENSG00000141736	0.1838267625953871	[951,1009]	[1055,746]	6	dCas9-KRAB	negative selection	5477692
39687984	39688007	17	+	27661255	K562	viability	GCAGGACCAACCGCGCCGCCAGG	ERBB2	ENSG00000141736	0.4149501322440537	[509,658]	[725,528]	9	dCas9-KRAB	negative selection	5501402
39688002	39688025	17	-	27661255	K562	viability	GGGAGAAAGGATGGCCGGCCTGG	ERBB2	ENSG00000141736	0.02600436632908315	[898,964]	[823,699]	0	dCas9-KRAB	negative selection	5501403
39715516	39715539	17	-	27260156	BXPC3	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.201828761661083	[188]	[132,182,244,123]	-4	hSpCas9	negative selection	5541562
39712036	39712059	17	-	27260156	BXPC3	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.271852424432933	[251]	[289,365,328,280]	6	hSpCas9	negative selection	5541563
39715450	39715473	17	-	27260156	BXPC3	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.21423268769879047	[504]	[405,420,464,543]	-5	hSpCas9	negative selection	5541564
39712365	39712388	17	+	27260156	BXPC3	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.5742741388122773	[786]	[411,498,700,624]	-8	hSpCas9	negative selection	5605827
39712426	39712449	17	+	27260156	BXPC3	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.4555543089425498	[558]	[834,778,802,777]	8	hSpCas9	negative selection	5605828
39711968	39711991	17	+	27260156	BXPC3	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	-0.4213468540984982	[688]	[492,523,457,696]	-7	hSpCas9	negative selection	5605829
39715516	39715539	17	-	27260156	A673	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.21857619220280133	[188]	[235,269,298,245]	5	hSpCas9	negative selection	5662813
39712036	39712059	17	-	27260156	A673	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.44957179508519474	[251]	[450,397,335,475]	8	hSpCas9	negative selection	5662814
39715450	39715473	17	-	27260156	A673	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.39760800782032396	[504]	[706,780,698,1008]	8	hSpCas9	negative selection	5662815
39712365	39712388	17	+	27260156	A673	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.159119331716438	[786]	[892,738,796,969]	-4	hSpCas9	negative selection	5727078
39712426	39712449	17	+	27260156	A673	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.3460604290553978	[558]	[843,901,692,977]	7	hSpCas9	negative selection	5727079
39711968	39711991	17	+	27260156	A673	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.4157598917304134	[688]	[1199,1104,871,1256]	8	hSpCas9	negative selection	5727080
39715516	39715539	17	-	27260156	A375	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.08336829946820012	[188]	[109,168,349,288]	1	hSpCas9	negative selection	5784064
39712036	39712059	17	-	27260156	A375	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.32407887371611466	[251]	[277,393,588,230]	5	hSpCas9	negative selection	5784065
39715450	39715473	17	-	27260156	A375	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.2352443647007434	[504]	[754,773,534,718]	3	hSpCas9	negative selection	5784066
39712365	39712388	17	+	27260156	A375	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	0.09609883362028515	[786]	[674,1455,803,1046]	1	hSpCas9	negative selection	5848329
39712426	39712449	17	+	27260156	A375	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	1.0095287267654849	[558]	[1304,1422,1356,1196]	9	hSpCas9	negative selection	5848330
39711968	39711991	17	+	27260156	A375	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.04472594484150605	[688]	[705,1148,762,751]	0	hSpCas9	negative selection	5848331
39715516	39715539	17	-	27260156	COLO741	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.11644364320818301	[188]	[271,298,217]	2	hSpCas9	negative selection	5905315
39712036	39712059	17	-	27260156	COLO741	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.08632322427980521	[251]	[369,369,290]	1	hSpCas9	negative selection	5905316
39715450	39715473	17	-	27260156	COLO741	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.3853097558032805	[504]	[969,682,880]	7	hSpCas9	negative selection	5905317
39712365	39712388	17	+	27260156	COLO741	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	0.019023505192444112	[786]	[1037,1026,992]	0	hSpCas9	negative selection	5969580
39712426	39712449	17	+	27260156	COLO741	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.3442149795009022	[558]	[960,902,861]	7	hSpCas9	negative selection	5969581
39711968	39711991	17	+	27260156	COLO741	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.22899921597323625	[688]	[1236,924,953]	5	hSpCas9	negative selection	5969582
39715516	39715539	17	-	27260156	CAL120	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.15171336647215816	[188]	[234,129,411]	2	hSpCas9	negative selection	6026566
39712036	39712059	17	-	27260156	CAL120	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.6815438511049642	[251]	[832,373,353]	8	hSpCas9	negative selection	6026567
39715450	39715473	17	-	27260156	CAL120	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.18351267322023485	[504]	[812,705,637]	2	hSpCas9	negative selection	6026568
39712365	39712388	17	+	27260156	CAL120	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.007086708660954288	[786]	[1326,661,986]	0	hSpCas9	negative selection	6090831
39712426	39712449	17	+	27260156	CAL120	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.45977142149726846	[558]	[1217,1069,626]	7	hSpCas9	negative selection	6090832
39711968	39711991	17	+	27260156	CAL120	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.28114692409536757	[688]	[1274,942,943]	4	hSpCas9	negative selection	6090833
39715516	39715539	17	-	27260156	CADOES1	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.00532043261737436	[188]	[283,87,205,119]	0	hSpCas9	negative selection	6147817
39712036	39712059	17	-	27260156	CADOES1	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.5162745113020293	[251]	[285,250,513,287]	8	hSpCas9	negative selection	6147818
39715450	39715473	17	-	27260156	CADOES1	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.04547348923716475	[504]	[524,435,560,413]	0	hSpCas9	negative selection	6147819
39712365	39712388	17	+	27260156	CADOES1	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.007586457778535616	[786]	[646,903,609,752]	0	hSpCas9	negative selection	6212082
39712426	39712449	17	+	27260156	CADOES1	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.5435106115522306	[558]	[737,764,798,727]	8	hSpCas9	negative selection	6212083
39711968	39711991	17	+	27260156	CADOES1	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.057424515618415994	[688]	[619,678,585,786]	1	hSpCas9	negative selection	6212084
39715516	39715539	17	-	27260156	EWS502	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.08602799520352145	[188]	[184,303,126,232]	1	hSpCas9	negative selection	6269068
39712036	39712059	17	-	27260156	EWS502	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.4160404585458983	[251]	[288,413,387,336]	7	hSpCas9	negative selection	6269069
39715450	39715473	17	-	27260156	EWS502	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.21387302626450266	[504]	[403,812,563,722]	4	hSpCas9	negative selection	6269070
39712365	39712388	17	+	27260156	EWS502	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.19438702407544495	[786]	[734,572,670,952]	-3	hSpCas9	negative selection	6333333
39712426	39712449	17	+	27260156	EWS502	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.6741638175985696	[558]	[763,1063,1237,713]	9	hSpCas9	negative selection	6333334
39711968	39711991	17	+	27260156	EWS502	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.3798101349655497	[688]	[980,917,861,1035]	6	hSpCas9	negative selection	6333335
39715516	39715539	17	-	27260156	EW8	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.1305425942732643	[188]	[187,195,135,157]	2	hSpCas9	negative selection	6390319
39712036	39712059	17	-	27260156	EW8	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.5086954605591097	[251]	[361,303,209,306]	8	hSpCas9	negative selection	6390320
39715450	39715473	17	-	27260156	EW8	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.2921573445701805	[504]	[408,458,358,788]	5	hSpCas9	negative selection	6390321
39712365	39712388	17	+	27260156	EW8	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.05089187193376643	[786]	[882,560,607,439]	-1	hSpCas9	negative selection	6454584
39712426	39712449	17	+	27260156	EW8	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.4182378489295543	[558]	[601,618,607,589]	7	hSpCas9	negative selection	6454585
39711968	39711991	17	+	27260156	EW8	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.24518158586487449	[688]	[694,550,692,703]	4	hSpCas9	negative selection	6454586
39715516	39715539	17	-	27260156	CORL105	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.1433241783299386	[188]	[226,286,293,175]	2	hSpCas9	negative selection	6511570
39712036	39712059	17	-	27260156	CORL105	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	-0.045293540065288185	[251]	[312,190,285,355]	-1	hSpCas9	negative selection	6511571
39715450	39715473	17	-	27260156	CORL105	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.17810800713990455	[504]	[617,556,421,479]	-3	hSpCas9	negative selection	6511572
39712365	39712388	17	+	27260156	CORL105	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.17703880877599265	[786]	[814,749,980,740]	-3	hSpCas9	negative selection	6575835
39712426	39712449	17	+	27260156	CORL105	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.5926941604450037	[558]	[1168,807,936,1034]	9	hSpCas9	negative selection	6575836
39711968	39711991	17	+	27260156	CORL105	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.16525236191774872	[688]	[821,750,1367,749]	3	hSpCas9	negative selection	6575837
39715516	39715539	17	-	27260156	HS294T	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.322266492832912	[188]	[65,56,40,70]	-4	hSpCas9	negative selection	6632821
39712036	39712059	17	-	27260156	HS294T	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.3152966758305903	[251]	[114,104,157,104]	4	hSpCas9	negative selection	6632822
39715450	39715473	17	-	27260156	HS294T	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.3283723336723775	[504]	[205,190,330,259]	4	hSpCas9	negative selection	6632823
39712365	39712388	17	+	27260156	HS294T	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.13529667526779432	[786]	[219,315,250,333]	-2	hSpCas9	negative selection	6697086
39712426	39712449	17	+	27260156	HS294T	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.26542208624299957	[558]	[202,294,257,291]	3	hSpCas9	negative selection	6697087
39711968	39711991	17	+	27260156	HS294T	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.18871048397486612	[688]	[329,254,316,311]	2	hSpCas9	negative selection	6697088
39715516	39715539	17	-	27260156	HCC44	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.2213009857267978	[188]	[218,148,390,270]	3	hSpCas9	negative selection	6754072
39712036	39712059	17	-	27260156	HCC44	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.4021507700361603	[251]	[256,483,352,378]	6	hSpCas9	negative selection	6754073
39715450	39715473	17	-	27260156	HCC44	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.15887409580526285	[504]	[469,576,1085,487]	2	hSpCas9	negative selection	6754074
39712365	39712388	17	+	27260156	HCC44	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.2037744776561402	[786]	[702,694,787,901]	-3	hSpCas9	negative selection	6818337
39712426	39712449	17	+	27260156	HCC44	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.3504649678764412	[558]	[686,727,1228,651]	6	hSpCas9	negative selection	6818338
39711968	39711991	17	+	27260156	HCC44	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.2535670943748114	[688]	[932,659,1302,915]	4	hSpCas9	negative selection	6818339
39715516	39715539	17	-	27260156	G402	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.12137496777704126	[188]	[62,150,286,315]	-1	hSpCas9	negative selection	6875323
39712036	39712059	17	-	27260156	G402	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.5700027286044852	[251]	[959,540,245,168]	7	hSpCas9	negative selection	6875324
39715450	39715473	17	-	27260156	G402	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.5705357774189842	[504]	[1032,711,978,936]	7	hSpCas9	negative selection	6875325
39712365	39712388	17	+	27260156	G402	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	0.036861199828533975	[786]	[1260,808,966,931]	0	hSpCas9	negative selection	6939588
39712426	39712449	17	+	27260156	G402	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.7858082105092494	[558]	[1562,1277,995,935]	8	hSpCas9	negative selection	6939589
39711968	39711991	17	+	27260156	G402	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.1179659158400419	[688]	[1116,928,815,818]	1	hSpCas9	negative selection	6939590
39715516	39715539	17	-	27260156	L33	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.06051050343900166	[188]	[167,56,172,206]	1	hSpCas9	negative selection	6996574
39712036	39712059	17	-	27260156	L33	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.23757300203164444	[251]	[300,113,185,312]	5	hSpCas9	negative selection	6996575
39715450	39715473	17	-	27260156	L33	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.32959500219418525	[504]	[680,263,320,699]	7	hSpCas9	negative selection	6996576
39712365	39712388	17	+	27260156	L33	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.3164911138062064	[786]	[626,274,374,632]	-6	hSpCas9	negative selection	7060839
39712426	39712449	17	+	27260156	L33	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.3232019513038914	[558]	[692,299,382,761]	6	hSpCas9	negative selection	7060840
39711968	39711991	17	+	27260156	L33	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	-0.1292715150232226	[688]	[522,285,365,717]	-3	hSpCas9	negative selection	7060841
39715516	39715539	17	-	27260156	K562	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.029997865789646916	[188]	[174,156,153,194]	0	hSpCas9	negative selection	7117825
39712036	39712059	17	-	27260156	K562	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.4635640530245003	[251]	[289,683,133,159]	6	hSpCas9	negative selection	7117826
39715450	39715473	17	-	27260156	K562	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.297759307124657	[504]	[479,397,858,460]	4	hSpCas9	negative selection	7117827
39712365	39712388	17	+	27260156	K562	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	0.2342276712337945	[786]	[552,1073,1156,524]	3	hSpCas9	negative selection	7182090
39712426	39712449	17	+	27260156	K562	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.5851726768324257	[558]	[545,752,707,928]	7	hSpCas9	negative selection	7182091
39711968	39711991	17	+	27260156	K562	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.43014877952237407	[688]	[878,670,722,994]	5	hSpCas9	negative selection	7182092
39715516	39715539	17	-	27260156	HT29	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.2736334358625372	[188]	[194,294,139,143]	-5	hSpCas9	negative selection	7239076
39712036	39712059	17	-	27260156	HT29	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.0493289750232776	[251]	[382,211,450,226]	0	hSpCas9	negative selection	7239077
39715450	39715473	17	-	27260156	HT29	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.1508385222022483	[504]	[607,487,553,555]	-3	hSpCas9	negative selection	7239078
39712365	39712388	17	+	27260156	HT29	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.33604924901422456	[786]	[818,978,935,364]	-6	hSpCas9	negative selection	7303341
39712426	39712449	17	+	27260156	HT29	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.42349203197012686	[558]	[901,1254,701,819]	7	hSpCas9	negative selection	7303342
39711968	39711991	17	+	27260156	HT29	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	-0.10372226452436895	[688]	[770,683,946,709]	-2	hSpCas9	negative selection	7303343
39715516	39715539	17	-	27260156	MHHES1	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.44842963004169456	[188]	[457,341,198,201]	7	hSpCas9	negative selection	7360327
39712036	39712059	17	-	27260156	MHHES1	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.2061258377632884	[251]	[507,281,274,267]	4	hSpCas9	negative selection	7360328
39715450	39715473	17	-	27260156	MHHES1	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.04255901890456532	[504]	[718,465,616,433]	0	hSpCas9	negative selection	7360329
39712365	39712388	17	+	27260156	MHHES1	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.2189397522541895	[786]	[940,668,849,615]	-4	hSpCas9	negative selection	7424592
39712426	39712449	17	+	27260156	MHHES1	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.3837023718317978	[558]	[1302,785,628,643]	7	hSpCas9	negative selection	7424593
39711968	39711991	17	+	27260156	MHHES1	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.3236683582856753	[688]	[1099,870,1217,735]	6	hSpCas9	negative selection	7424594
39715516	39715539	17	-	27260156	MEWO	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.12155553225009452	[188]	[196,211,84]	-3	hSpCas9	negative selection	7481578
39712036	39712059	17	-	27260156	MEWO	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.11575634632369913	[251]	[244,314,203]	2	hSpCas9	negative selection	7481579
39715450	39715473	17	-	27260156	MEWO	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.1578271518843848	[504]	[546,521,515]	3	hSpCas9	negative selection	7481580
39712365	39712388	17	+	27260156	MEWO	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.25180285527214924	[786]	[546,646,646]	-5	hSpCas9	negative selection	7545843
39712426	39712449	17	+	27260156	MEWO	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.1582562070028663	[558]	[649,494,618]	3	hSpCas9	negative selection	7545844
39711968	39711991	17	+	27260156	MEWO	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.33112351444087895	[688]	[990,692,783]	7	hSpCas9	negative selection	7545845
39715516	39715539	17	-	27260156	LNCAPCLONEFGC	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.3181549469434165	[188]	[139,215,240,261]	5	hSpCas9	negative selection	7602829
39712036	39712059	17	-	27260156	LNCAPCLONEFGC	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.16490358697103047	[251]	[250,250,242,276]	2	hSpCas9	negative selection	7602830
39715450	39715473	17	-	27260156	LNCAPCLONEFGC	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.03994749814311929	[504]	[424,471,571,327]	0	hSpCas9	negative selection	7602831
39712365	39712388	17	+	27260156	LNCAPCLONEFGC	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.049662466156395024	[786]	[722,566,775,708]	-1	hSpCas9	negative selection	7667094
39712426	39712449	17	+	27260156	LNCAPCLONEFGC	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.4867125244922371	[558]	[508,776,795,767]	7	hSpCas9	negative selection	7667095
39711968	39711991	17	+	27260156	LNCAPCLONEFGC	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.28656088653772505	[688]	[757,685,810,801]	4	hSpCas9	negative selection	7667096
39715516	39715539	17	-	27260156	PANC0327	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.40632239462164466	[188]	[182,163,137,408]	6	hSpCas9	negative selection	7724080
39712036	39712059	17	-	27260156	PANC0327	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.0537062932679675	[251]	[208,234,216,265]	0	hSpCas9	negative selection	7724081
39715450	39715473	17	-	27260156	PANC0327	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.3551472701366904	[504]	[480,711,722,353]	5	hSpCas9	negative selection	7724082
39712365	39712388	17	+	27260156	PANC0327	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.02247412237728752	[786]	[978,523,661,632]	0	hSpCas9	negative selection	7788345
39712426	39712449	17	+	27260156	PANC0327	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.490667647599062	[558]	[947,751,537,565]	7	hSpCas9	negative selection	7788346
39711968	39711991	17	+	27260156	PANC0327	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.19732640461491235	[688]	[693,689,842,580]	3	hSpCas9	negative selection	7788347
39715516	39715539	17	-	27260156	NCIH2009	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.10726750635202165	[188]	[244,243,245]	-1	hSpCas9	negative selection	7845331
39712036	39712059	17	-	27260156	NCIH2009	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.681322017863237	[251]	[607,367,728]	8	hSpCas9	negative selection	7845332
39715450	39715473	17	-	27260156	NCIH2009	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.2795949914566139	[504]	[774,585,419]	-4	hSpCas9	negative selection	7845333
39712365	39712388	17	+	27260156	NCIH2009	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.17970706732355468	[786]	[1071,1064,791]	-2	hSpCas9	negative selection	7909596
39712426	39712449	17	+	27260156	NCIH2009	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.8632375209446748	[558]	[1763,1292,1272]	9	hSpCas9	negative selection	7909597
39711968	39711991	17	+	27260156	NCIH2009	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.3157958725850436	[688]	[1163,1131,1290]	4	hSpCas9	negative selection	7909598
39715516	39715539	17	-	27260156	NCIH1373	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.43815457074389297	[188]	[800,226,63,35]	4	hSpCas9	negative selection	7966582
39712036	39712059	17	-	27260156	NCIH1373	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.5829149410463202	[251]	[970,368,247,47]	6	hSpCas9	negative selection	7966583
39715450	39715473	17	-	27260156	NCIH1373	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.07273952298992085	[504]	[431,442,587,180]	0	hSpCas9	negative selection	7966584
39712365	39712388	17	+	27260156	NCIH1373	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.4173973073680657	[786]	[912,281,563,257]	-4	hSpCas9	negative selection	8030847
39712426	39712449	17	+	27260156	NCIH1373	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.675107169131602	[558]	[994,1164,620,319]	6	hSpCas9	negative selection	8030848
39711968	39711991	17	+	27260156	NCIH1373	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	-0.38370208618351687	[688]	[921,433,520,145]	-4	hSpCas9	negative selection	8030849
39715516	39715539	17	-	27260156	PATU8902	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.7248516053393471	[188]	[203,775,399,360]	7	hSpCas9	negative selection	8087833
39712036	39712059	17	-	27260156	PATU8902	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.4705489175404216	[251]	[190,489,209,1212]	5	hSpCas9	negative selection	8087834
39715450	39715473	17	-	27260156	PATU8902	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.8404335289821065	[504]	[273,337,412,558]	-7	hSpCas9	negative selection	8087835
39712365	39712388	17	+	27260156	PATU8902	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	0.05562218688161846	[786]	[1177,1026,816,1671]	0	hSpCas9	negative selection	8152098
39712426	39712449	17	+	27260156	PATU8902	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.9912098574620591	[558]	[1463,1786,1236,1802]	9	hSpCas9	negative selection	8152099
39711968	39711991	17	+	27260156	PATU8902	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	-0.3873455790536119	[688]	[744,632,868,633]	-4	hSpCas9	negative selection	8152100
39715516	39715539	17	-	27260156	PANC1	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.05109109935992229	[188]	[78,221,125,203]	-1	hSpCas9	negative selection	8209084
39712036	39712059	17	-	27260156	PANC1	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.24321993885229654	[251]	[252,299,145,318]	4	hSpCas9	negative selection	8209085
39715450	39715473	17	-	27260156	PANC1	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.31031635546209846	[504]	[507,685,403,568]	5	hSpCas9	negative selection	8209086
39712365	39712388	17	+	27260156	PANC1	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.21703710498366213	[786]	[545,680,487,615]	-4	hSpCas9	negative selection	8273349
39712426	39712449	17	+	27260156	PANC1	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.3948264581094124	[558]	[557,907,529,583]	6	hSpCas9	negative selection	8273350
39711968	39711991	17	+	27260156	PANC1	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.10228353764220599	[688]	[691,684,734,457]	1	hSpCas9	negative selection	8273351
39715516	39715539	17	-	27260156	PANC0813	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.20055157704429605	[188]	[261,198,236,318]	3	hSpCas9	negative selection	8330335
39712036	39712059	17	-	27260156	PANC0813	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.40248669425657124	[251]	[460,335,333,436]	6	hSpCas9	negative selection	8330336
39715450	39715473	17	-	27260156	PANC0813	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.2071068885745258	[504]	[768,589,635,746]	3	hSpCas9	negative selection	8330337
39712365	39712388	17	+	27260156	PANC0813	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.30971103351734264	[786]	[857,503,673,944]	-5	hSpCas9	negative selection	8394600
39712426	39712449	17	+	27260156	PANC0813	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.7339616521862362	[558]	[1259,973,832,1301]	9	hSpCas9	negative selection	8394601
39711968	39711991	17	+	27260156	PANC0813	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.3432271747104605	[688]	[1018,1191,753,1131]	5	hSpCas9	negative selection	8394602
39715516	39715539	17	-	27260156	RDES	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.22331326882697589	[188]	[182,216,336,299]	3	hSpCas9	negative selection	8451586
39712036	39712059	17	-	27260156	RDES	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.3566805605420318	[251]	[329,313,358,503]	6	hSpCas9	negative selection	8451587
39715450	39715473	17	-	27260156	RDES	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.10166441321946157	[504]	[560,458,521,618]	-2	hSpCas9	negative selection	8451588
39712365	39712388	17	+	27260156	RDES	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.23305163002137552	[786]	[666,711,745,991]	-4	hSpCas9	negative selection	8515851
39712426	39712449	17	+	27260156	RDES	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.6180467372943277	[558]	[855,1011,756,1364]	8	hSpCas9	negative selection	8515852
39711968	39711991	17	+	27260156	RDES	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.018916788859125844	[688]	[682,753,863,938]	0	hSpCas9	negative selection	8515853
39715516	39715539	17	-	27260156	PC3	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.2637558186717224	[188]	[138,174,540,190]	6	hSpCas9	negative selection	8572837
39712036	39712059	17	-	27260156	PC3	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.24747206463668414	[251]	[226,197,684,233]	5	hSpCas9	negative selection	8572838
39715450	39715473	17	-	27260156	PC3	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.02056593672671668	[504]	[338,440,726,591]	0	hSpCas9	negative selection	8572839
39712365	39712388	17	+	27260156	PC3	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.12643648725982204	[786]	[549,570,1239,715]	-3	hSpCas9	negative selection	8637102
39712426	39712449	17	+	27260156	PC3	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.23735679055343573	[558]	[404,539,1281,700]	5	hSpCas9	negative selection	8637103
39711968	39711991	17	+	27260156	PC3	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.37600421856979405	[688]	[622,864,1513,825]	7	hSpCas9	negative selection	8637104
39715516	39715539	17	-	27260156	PATU8988T	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.3920098806892929	[188]	[140,236,79,105]	-6	hSpCas9	negative selection	8694088
39712036	39712059	17	-	27260156	PATU8988T	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.04589099670986341	[251]	[200,262,319,218]	0	hSpCas9	negative selection	8694089
39715450	39715473	17	-	27260156	PATU8988T	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.14989157611569848	[504]	[559,588,644,359]	2	hSpCas9	negative selection	8694090
39712365	39712388	17	+	27260156	PATU8988T	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.19585507289743342	[786]	[469,642,714,838]	-3	hSpCas9	negative selection	8758353
39712426	39712449	17	+	27260156	PATU8988T	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.5451089952684913	[558]	[692,1019,613,854]	8	hSpCas9	negative selection	8758354
39711968	39711991	17	+	27260156	PATU8988T	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.12535567866650166	[688]	[525,806,758,827]	2	hSpCas9	negative selection	8758355
39715516	39715539	17	-	27260156	T47D	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	-0.1492469201821771	[188]	[144,170,198,283]	-3	hSpCas9	negative selection	8815339
39712036	39712059	17	-	27260156	T47D	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	-0.061953519361008014	[251]	[340,216,281,290]	-1	hSpCas9	negative selection	8815340
39715450	39715473	17	-	27260156	T47D	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	-0.3450848553375856	[504]	[462,384,525,484]	-6	hSpCas9	negative selection	8815341
39712365	39712388	17	+	27260156	T47D	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.34421967787652075	[786]	[722,678,700,791]	-6	hSpCas9	negative selection	8879604
39712426	39712449	17	+	27260156	T47D	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.45947740901076783	[558]	[943,839,894,907]	8	hSpCas9	negative selection	8879605
39711968	39711991	17	+	27260156	T47D	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	-0.2510428256733889	[688]	[722,551,701,732]	-5	hSpCas9	negative selection	8879606
39715516	39715539	17	-	27260156	SU8686	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.16256193234679062	[188]	[196,210,251,173]	2	hSpCas9	negative selection	8936590
39712036	39712059	17	-	27260156	SU8686	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.31509492409546147	[251]	[288,262,406,289]	5	hSpCas9	negative selection	8936591
39715450	39715473	17	-	27260156	SU8686	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.2663965938084115	[504]	[476,555,676,738]	4	hSpCas9	negative selection	8936592
39712365	39712388	17	+	27260156	SU8686	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	0.03577854685386772	[786]	[682,617,827,1160]	0	hSpCas9	negative selection	9000855
39712426	39712449	17	+	27260156	SU8686	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.5829626422194905	[558]	[659,768,698,1283]	8	hSpCas9	negative selection	9000856
39711968	39711991	17	+	27260156	SU8686	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.22017029272820987	[688]	[705,693,658,1203]	4	hSpCas9	negative selection	9000857
39715516	39715539	17	-	27260156	SKES1	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.01249155534899482	[188]	[157,256,243,111]	0	hSpCas9	negative selection	9057841
39712036	39712059	17	-	27260156	SKES1	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.1871440982835192	[251]	[332,332,254,238]	4	hSpCas9	negative selection	9057842
39715450	39715473	17	-	27260156	SKES1	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.366828243141709	[504]	[704,725,612,573]	7	hSpCas9	negative selection	9057843
39712365	39712388	17	+	27260156	SKES1	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.1951785892347223	[786]	[696,701,659,680]	-4	hSpCas9	negative selection	9122106
39712426	39712449	17	+	27260156	SKES1	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.31405261234761916	[558]	[691,851,648,602]	6	hSpCas9	negative selection	9122107
39711968	39711991	17	+	27260156	SKES1	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.3781934158898639	[688]	[1029,901,765,887]	7	hSpCas9	negative selection	9122108
39715516	39715539	17	-	27260156	TOV112D	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.1493873417578706	[188]	[181,354,133,201]	3	hSpCas9	negative selection	9179092
39712036	39712059	17	-	27260156	TOV112D	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.4387595507782753	[251]	[480,396,243,272]	7	hSpCas9	negative selection	9179093
39715450	39715473	17	-	27260156	TOV112D	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.16563790923748745	[504]	[728,480,457,591]	3	hSpCas9	negative selection	9179094
39712365	39712388	17	+	27260156	TOV112D	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.25428214568235613	[786]	[670,1001,316,734]	-5	hSpCas9	negative selection	9243357
39712426	39712449	17	+	27260156	TOV112D	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.5447851197007473	[558]	[841,841,956,637]	8	hSpCas9	negative selection	9243358
39711968	39711991	17	+	27260156	TOV112D	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.09752828378759237	[688]	[740,861,758,623]	2	hSpCas9	negative selection	9243359
39715516	39715539	17	-	27260156	TC71	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.021465066043097947	[188]	[173,214,192,243]	0	hSpCas9	negative selection	9300343
39712036	39712059	17	-	27260156	TC71	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.14855260192036834	[251]	[290,283,273,352]	4	hSpCas9	negative selection	9300344
39715450	39715473	17	-	27260156	TC71	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.1931666444161404	[504]	[667,534,594,680]	5	hSpCas9	negative selection	9300345
39712365	39712388	17	+	27260156	TC71	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.2759602291751897	[786]	[535,801,779,667]	-6	hSpCas9	negative selection	9364608
39712426	39712449	17	+	27260156	TC71	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.2805464298552235	[558]	[654,784,618,865]	6	hSpCas9	negative selection	9364609
39711968	39711991	17	+	27260156	TC71	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.14618281131853106	[688]	[676,815,805,983]	3	hSpCas9	negative selection	9364610
39715516	39715539	17	-	27260156	TC32	viability	ACTTGTGCAGAATTCGTCCCCGG	ERBB2	ENSG00000141736	0.18593170942981274	[188]	[139,210,206,244]	3	hSpCas9	negative selection	9421594
39712036	39712059	17	-	27260156	TC32	viability	TGAGTGGGTACCTCGGGCACAGG	ERBB2	ENSG00000141736	0.3123349271648117	[251]	[208,181,479,379]	5	hSpCas9	negative selection	9421595
39715450	39715473	17	-	27260156	TC32	viability	CCGGCCATGCTGAGATGTATAGG	ERBB2	ENSG00000141736	0.1699485385815689	[504]	[512,417,537,689]	3	hSpCas9	negative selection	9421596
39712365	39712388	17	+	27260156	TC32	viability	AGTTACCAGTGCCAATATCCAGG	ERBB2	ENSG00000141736	-0.21377477685020918	[786]	[527,560,782,711]	-4	hSpCas9	negative selection	9485859
39712426	39712449	17	+	27260156	TC32	viability	TTTCTGCCGGAGAGCTTTGATGG	ERBB2	ENSG00000141736	0.5887825336455074	[558]	[821,462,1102,907]	8	hSpCas9	negative selection	9485860
39711968	39711991	17	+	27260156	TC32	viability	CTGCCCCCTGCACAACCAAGAGG	ERBB2	ENSG00000141736	0.07615175016097342	[688]	[710,405,828,882]	1	hSpCas9	negative selection	9485861
39700220	39700243	17	+	27869803	HPAFII	viability after 27 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.3392144631473546	[597]	[316,464,NaN]	2	hSpCas9	negative selection	9560451
39707049	39707072	17	+	27869803	HPAFII	viability after 27 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.655353224409515	[322]	[79,130,NaN]	-5	hSpCas9	negative selection	9560452
39708439	39708462	17	-	27869803	HPAFII	viability after 27 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	-0.5581624413774411	[414]	[103,184,NaN]	-4	hSpCas9	negative selection	9560454
39709313	39709336	17	+	27869803	HPAFII	viability after 27 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.9178324778241412	[377]	[357,389,NaN]	7	hSpCas9	negative selection	9560455
39709817	39709840	17	-	27869803	HPAFII	viability after 27 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.7100729644357686	[544]	[309,600,NaN]	6	hSpCas9	negative selection	9560456
39710088	39710111	17	+	27869803	HPAFII	viability after 27 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	1.4292439917771178	[248]	[45,607,NaN]	9	hSpCas9	negative selection	9560457
39700220	39700243	17	+	27869803	HPAFII	viability after 15 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	-0.00839558548888375	[597]	[736,577,NaN]	0	hSpCas9	negative selection	9642900
39707049	39707072	17	+	27869803	HPAFII	viability after 15 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.2979525014040017	[322]	[253,299,NaN]	-3	hSpCas9	negative selection	9642901
39708439	39708462	17	-	27869803	HPAFII	viability after 15 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.07311630665135771	[414]	[639,362,NaN]	0	hSpCas9	negative selection	9642903
39709313	39709336	17	+	27869803	HPAFII	viability after 15 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.9348387589882209	[377]	[931,679,NaN]	8	hSpCas9	negative selection	9642904
39709817	39709840	17	-	27869803	HPAFII	viability after 15 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.5832063732224975	[544]	[1117,727,NaN]	6	hSpCas9	negative selection	9642905
39710088	39710111	17	+	27869803	HPAFII	viability after 15 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	0.09081506212595876	[248]	[54,427,NaN]	1	hSpCas9	negative selection	9642906
39700220	39700243	17	+	27869803	ASPC1	viability after 36 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.44521097716429625	[1255]	[781,990,147]	4	hSpCas9	negative selection	9725349
39707049	39707072	17	+	27869803	ASPC1	viability after 36 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	0.31636324158688567	[571]	[82,360,272]	3	hSpCas9	negative selection	9725350
39708439	39708462	17	-	27869803	ASPC1	viability after 36 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	0.7401174695036721	[864]	[516,593,418]	7	hSpCas9	negative selection	9725352
39709313	39709336	17	+	27869803	ASPC1	viability after 36 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.21471560724030747	[1002]	[501,642,146]	2	hSpCas9	negative selection	9725353
39709817	39709840	17	-	27869803	ASPC1	viability after 36 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.25025915832438383	[1218]	[338,299,412]	-3	hSpCas9	negative selection	9725354
39710088	39710111	17	+	27869803	ASPC1	viability after 36 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	-0.06607179134332802	[530]	[260,150,136]	0	hSpCas9	negative selection	9725355
39700220	39700243	17	+	27869803	PATU8988S	viability after 35 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.7581108100178018	[1075]	[920,543,NaN]	7	hSpCas9	negative selection	9807798
39707049	39707072	17	+	27869803	PATU8988S	viability after 35 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.21879641498463165	[591]	[150,258,NaN]	-2	hSpCas9	negative selection	9807799
39708439	39708462	17	-	27869803	PATU8988S	viability after 35 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	-0.6668961227380228	[925]	[192,276,NaN]	-6	hSpCas9	negative selection	9807801
39709313	39709336	17	+	27869803	PATU8988S	viability after 35 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.35321792348975634	[967]	[172,437,NaN]	-4	hSpCas9	negative selection	9807802
39709817	39709840	17	-	27869803	PATU8988S	viability after 35 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.9305588146773794	[1184]	[204,295,NaN]	-7	hSpCas9	negative selection	9807803
39710088	39710111	17	+	27869803	PATU8988S	viability after 35 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	-0.1554092018331184	[550]	[309,87,NaN]	-2	hSpCas9	negative selection	9807804
39700220	39700243	17	+	27869803	PATU8988S	viability after 31 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.646109565185123	[1075]	[648,699,NaN]	7	hSpCas9	negative selection	9890247
39707049	39707072	17	+	27869803	PATU8988S	viability after 31 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.8395093345563933	[591]	[112,155,NaN]	-7	hSpCas9	negative selection	9890248
39708439	39708462	17	-	27869803	PATU8988S	viability after 31 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	-0.5289763602749286	[925]	[148,391,NaN]	-5	hSpCas9	negative selection	9890250
39709313	39709336	17	+	27869803	PATU8988S	viability after 31 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	-0.7913494530338532	[967]	[138,329,NaN]	-7	hSpCas9	negative selection	9890251
39709817	39709840	17	-	27869803	PATU8988S	viability after 31 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	-0.9044597901254591	[1184]	[207,308,NaN]	-7	hSpCas9	negative selection	9890252
39710088	39710111	17	+	27869803	PATU8988S	viability after 31 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	-0.47779477957234207	[550]	[188,117,NaN]	-5	hSpCas9	negative selection	9890253
39700220	39700243	17	+	27869803	HPAFII	viability after 35 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.2992370722989486	[597]	[221,541,NaN]	2	hSpCas9	negative selection	9972696
39707049	39707072	17	+	27869803	HPAFII	viability after 35 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.7964095836400834	[322]	[40,153,NaN]	-5	hSpCas9	negative selection	9972697
39708439	39708462	17	-	27869803	HPAFII	viability after 35 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	-1.013233492351123	[414]	[41,173,NaN]	-5	hSpCas9	negative selection	9972699
39709313	39709336	17	+	27869803	HPAFII	viability after 35 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.9912465472343653	[377]	[370,390,NaN]	6	hSpCas9	negative selection	9972700
39709817	39709840	17	-	27869803	HPAFII	viability after 35 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	1.0107223283498283	[544]	[284,860,NaN]	6	hSpCas9	negative selection	9972701
39710088	39710111	17	+	27869803	HPAFII	viability after 35 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	1.8466366454905943	[248]	[14,946,NaN]	9	hSpCas9	negative selection	9972702
39700220	39700243	17	+	27869803	HPAFII	viability after 31 days	CGGAGCCGCAGTGAGCACCATGG	ERBB2	ENSG00000141736	0.25312266192557953	[597]	[309,497,NaN]	1	hSpCas9	negative selection	10055145
39707049	39707072	17	+	27869803	HPAFII	viability after 31 days	ATGCTCCGCCACCTCTACCAGGG	ERBB2	ENSG00000141736	-0.7103911060401802	[322]	[38,188,NaN]	-4	hSpCas9	negative selection	10055146
39708439	39708462	17	-	27869803	HPAFII	viability after 31 days	CGGGTCTCCATTGTCTAGCACGG	ERBB2	ENSG00000141736	-0.11410994520761764	[414]	[118,319,NaN]	-1	hSpCas9	negative selection	10055148
39709313	39709336	17	+	27869803	HPAFII	viability after 31 days	CACAGAGATCTTGAAAGGAGGGG	ERBB2	ENSG00000141736	0.9463297449455498	[377]	[336,486,NaN]	7	hSpCas9	negative selection	10055149
39709817	39709840	17	-	27869803	HPAFII	viability after 31 days	CCTTACACATCGGAGAACAGGGG	ERBB2	ENSG00000141736	0.5819449770506218	[544]	[308,619,NaN]	4	hSpCas9	negative selection	10055150
39710088	39710111	17	+	27869803	HPAFII	viability after 31 days	ACGCGCACTGTCTGTGCCGGTGG	ERBB2	ENSG00000141736	1.2878733058455918	[248]	[21,688,NaN]	8	hSpCas9	negative selection	10055151
39715845	39715868	17	-	28162770	P31FUJ	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.6168635225011898	[95]	[172]	7	hSpCas9	negative selection	10150923
39715795	39715818	17	+	28162770	P31FUJ	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.466292334634157	[347]	[295]	-4	hSpCas9	negative selection	10150924
39723436	39723459	17	+	28162770	P31FUJ	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	0.4552537892708812	[53]	[86]	5	hSpCas9	negative selection	10150925
39708378	39708401	17	-	28162770	P31FUJ	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	-0.7439156752482697	[237]	[166]	-5	hSpCas9	negative selection	10150926
39708472	39708495	17	-	28162770	P31FUJ	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	0.2638737638888226	[145]	[205]	3	hSpCas9	negative selection	10150927
39710357	39710380	17	-	28162770	P31FUJ	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.3813247291244668	[275]	[248]	-3	hSpCas9	negative selection	10150928
39710418	39710441	17	+	28162770	P31FUJ	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.3207731263323707	[354]	[333]	-3	hSpCas9	negative selection	10150929
39711994	39712017	17	+	28162770	P31FUJ	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.4183272202725237	[276]	[434]	4	hSpCas9	negative selection	10150930
39715307	39715330	17	-	28162770	P31FUJ	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	0.42431008206261334	[25]	[40]	5	hSpCas9	negative selection	10150931
39715486	39715509	17	-	28162770	P31FUJ	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	0.011781349313243594	[340]	[403]	0	hSpCas9	negative selection	10150932
39715845	39715868	17	-	28162770	TF1	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10320289
39715795	39715818	17	+	28162770	TF1	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10320290
39723436	39723459	17	+	28162770	TF1	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10320291
39708378	39708401	17	-	28162770	TF1	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10320292
39708472	39708495	17	-	28162770	TF1	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10320293
39710357	39710380	17	-	28162770	TF1	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10320294
39710418	39710441	17	+	28162770	TF1	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	NaN	[NaN]	[293]	1	hSpCas9	negative selection	10320295
39711994	39712017	17	+	28162770	TF1	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10320296
39715307	39715330	17	-	28162770	TF1	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10320297
39715486	39715509	17	-	28162770	TF1	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10320298
39715845	39715868	17	-	28162770	SKM1	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.4259258154215799	[31]	[75]	4	hSpCas9	negative selection	10489655
39715795	39715818	17	+	28162770	SKM1	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	0.6605990850694727	[72]	[203]	6	hSpCas9	negative selection	10489656
39723436	39723459	17	+	28162770	SKM1	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.7746959832436487	[29]	[30]	-5	hSpCas9	negative selection	10489657
39708378	39708401	17	-	28162770	SKM1	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	-0.39260890576609164	[74]	[100]	-3	hSpCas9	negative selection	10489658
39708472	39708495	17	-	28162770	SKM1	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.9970884045800966	[34]	[30]	-6	hSpCas9	negative selection	10489659
39710357	39710380	17	-	28162770	SKM1	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.5399663302581557	[87]	[106]	-4	hSpCas9	negative selection	10489660
39710418	39710441	17	+	28162770	SKM1	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.28856949794093134	[75]	[109]	-2	hSpCas9	negative selection	10489661
39711994	39712017	17	+	28162770	SKM1	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.4652802540584656	[58]	[143]	4	hSpCas9	negative selection	10489662
39715307	39715330	17	-	28162770	SKM1	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-0.8220016980220053	[3]	[3]	-6	hSpCas9	negative selection	10489663
39715486	39715509	17	-	28162770	SKM1	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.5589672921882118	[64]	[77]	-4	hSpCas9	negative selection	10489664
39715845	39715868	17	-	28162770	SKM1	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.4259258154215799	[31]	[75]	4	hSpCas9	negative selection	10659021
39715795	39715818	17	+	28162770	SKM1	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	0.6605990850694727	[72]	[203]	6	hSpCas9	negative selection	10659022
39723436	39723459	17	+	28162770	SKM1	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.7746959832436487	[29]	[30]	-5	hSpCas9	negative selection	10659023
39708378	39708401	17	-	28162770	SKM1	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	-0.39260890576609164	[74]	[100]	-3	hSpCas9	negative selection	10659024
39708472	39708495	17	-	28162770	SKM1	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.9970884045800966	[34]	[30]	-6	hSpCas9	negative selection	10659025
39710357	39710380	17	-	28162770	SKM1	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.5399663302581557	[87]	[106]	-4	hSpCas9	negative selection	10659026
39710418	39710441	17	+	28162770	SKM1	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.28856949794093134	[75]	[109]	-2	hSpCas9	negative selection	10659027
39711994	39712017	17	+	28162770	SKM1	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.4652802540584656	[58]	[143]	4	hSpCas9	negative selection	10659028
39715307	39715330	17	-	28162770	SKM1	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-0.8220016980220053	[3]	[3]	-6	hSpCas9	negative selection	10659029
39715486	39715509	17	-	28162770	SKM1	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.5589672921882118	[64]	[77]	-4	hSpCas9	negative selection	10659030
39715845	39715868	17	-	28162770	PL21	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.20013961448932	[121]	[60]	1	hSpCas9	negative selection	10828387
39715795	39715818	17	+	28162770	PL21	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	0.6329101996931864	[282]	[190]	5	hSpCas9	negative selection	10828388
39723436	39723459	17	+	28162770	PL21	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	1.251364937844493	[82]	[85]	8	hSpCas9	negative selection	10828389
39708378	39708401	17	-	28162770	PL21	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.6190294392637706	[186]	[124]	5	hSpCas9	negative selection	10828390
39708472	39708495	17	-	28162770	PL21	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.031185931617135454	[107]	[45]	0	hSpCas9	negative selection	10828391
39710357	39710380	17	-	28162770	PL21	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	0.07057998072040417	[325]	[148]	0	hSpCas9	negative selection	10828392
39710418	39710441	17	+	28162770	PL21	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.1263612101878664	[315]	[125]	-1	hSpCas9	negative selection	10828393
39711994	39712017	17	+	28162770	PL21	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-0.1970077258936345	[186]	[70]	-1	hSpCas9	negative selection	10828394
39715307	39715330	17	-	28162770	PL21	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-3.323422341567693	[22]	[0]	-9	hSpCas9	negative selection	10828395
39715486	39715509	17	-	28162770	PL21	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	0.5916223857892671	[246]	[161]	5	hSpCas9	negative selection	10828396
39715845	39715868	17	-	28162770	P31FUJ	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.6168635225011898	[95]	[172]	7	hSpCas9	negative selection	10997753
39715795	39715818	17	+	28162770	P31FUJ	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.466292334634157	[347]	[295]	-4	hSpCas9	negative selection	10997754
39723436	39723459	17	+	28162770	P31FUJ	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	0.4552537892708812	[53]	[86]	5	hSpCas9	negative selection	10997755
39708378	39708401	17	-	28162770	P31FUJ	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	-0.7439156752482697	[237]	[166]	-5	hSpCas9	negative selection	10997756
39708472	39708495	17	-	28162770	P31FUJ	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	0.2638737638888226	[145]	[205]	3	hSpCas9	negative selection	10997757
39710357	39710380	17	-	28162770	P31FUJ	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.3813247291244668	[275]	[248]	-3	hSpCas9	negative selection	10997758
39710418	39710441	17	+	28162770	P31FUJ	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.3207731263323707	[354]	[333]	-3	hSpCas9	negative selection	10997759
39711994	39712017	17	+	28162770	P31FUJ	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.4183272202725237	[276]	[434]	4	hSpCas9	negative selection	10997760
39715307	39715330	17	-	28162770	P31FUJ	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	0.42431008206261334	[25]	[40]	5	hSpCas9	negative selection	10997761
39715486	39715509	17	-	28162770	P31FUJ	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	0.011781349313243594	[340]	[403]	0	hSpCas9	negative selection	10997762
39715845	39715868	17	-	28162770	OCIAML5	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.5325972793713278	[35]	[93]	4	hSpCas9	negative selection	11167119
39715795	39715818	17	+	28162770	OCIAML5	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.3610802183518546	[184]	[259]	-3	hSpCas9	negative selection	11167120
39723436	39723459	17	+	28162770	OCIAML5	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	0.7461927524706167	[35]	[108]	6	hSpCas9	negative selection	11167121
39708378	39708401	17	-	28162770	OCIAML5	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.3997166999950878	[117]	[280]	3	hSpCas9	negative selection	11167122
39708472	39708495	17	-	28162770	OCIAML5	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-1.4214322165341349	[91]	[61]	-7	hSpCas9	negative selection	11167123
39710357	39710380	17	-	28162770	OCIAML5	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.358734545608409	[129]	[182]	-3	hSpCas9	negative selection	11167124
39710418	39710441	17	+	28162770	OCIAML5	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	0.3475609593403568	[218]	[502]	3	hSpCas9	negative selection	11167125
39711994	39712017	17	+	28162770	OCIAML5	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-0.4894964914792889	[174]	[224]	-3	hSpCas9	negative selection	11167126
39715307	39715330	17	-	28162770	OCIAML5	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	2.989235683116944	[2]	[42]	9	hSpCas9	negative selection	11167127
39715486	39715509	17	-	28162770	OCIAML5	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.862408515085456	[139]	[138]	-5	hSpCas9	negative selection	11167128
39715845	39715868	17	-	28162770	EOL1	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	-0.200343476257274	[204]	[93]	-1	hSpCas9	negative selection	11336485
39715795	39715818	17	+	28162770	EOL1	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	0.7409478332311459	[317]	[279]	6	hSpCas9	negative selection	11336486
39723436	39723459	17	+	28162770	EOL1	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.5060865827593279	[123]	[45]	-4	hSpCas9	negative selection	11336487
39708378	39708401	17	-	28162770	EOL1	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.2711055329666118	[452]	[287]	2	hSpCas9	negative selection	11336488
39708472	39708495	17	-	28162770	EOL1	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	0.4430148605047839	[295]	[211]	4	hSpCas9	negative selection	11336489
39710357	39710380	17	-	28162770	EOL1	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-1.1037160806481867	[566]	[138]	-6	hSpCas9	negative selection	11336490
39710418	39710441	17	+	28162770	EOL1	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.5514139519892487	[394]	[141]	-4	hSpCas9	negative selection	11336491
39711994	39712017	17	+	28162770	EOL1	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-0.19944094570491874	[339]	[155]	-1	hSpCas9	negative selection	11336492
39715307	39715330	17	-	28162770	EOL1	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-2.4677696512082257	[20]	[1]	-8	hSpCas9	negative selection	11336493
39715486	39715509	17	-	28162770	EOL1	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.13469143180414167	[347]	[166]	-1	hSpCas9	negative selection	11336494
39715845	39715868	17	-	28162770	MOLM13	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.5361953949354876	[164]	[172]	4	hSpCas9	negative selection	11505851
39715795	39715818	17	+	28162770	MOLM13	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.7969383061122657	[321]	[133]	-4	hSpCas9	negative selection	11505852
39723436	39723459	17	+	28162770	MOLM13	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	2.4415781044287317	[82]	[325]	9	hSpCas9	negative selection	11505853
39708378	39708401	17	-	28162770	MOLM13	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.042828154313492295	[336]	[250]	0	hSpCas9	negative selection	11505854
39708472	39708495	17	-	28162770	MOLM13	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	1.2375081930295364	[165]	[282]	8	hSpCas9	negative selection	11505855
39710357	39710380	17	-	28162770	MOLM13	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.05211767733580752	[455]	[317]	0	hSpCas9	negative selection	11505856
39710418	39710441	17	+	28162770	MOLM13	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.06262533515420099	[506]	[350]	0	hSpCas9	negative selection	11505857
39711994	39712017	17	+	28162770	MOLM13	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-1.3580812186803723	[389]	[109]	-6	hSpCas9	negative selection	11505858
39715307	39715330	17	-	28162770	MOLM13	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	1.6053929052945137	[59]	[131]	9	hSpCas9	negative selection	11505859
39715486	39715509	17	-	28162770	MOLM13	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-1.9850775733665873	[333]	[60]	-7	hSpCas9	negative selection	11505860
39715845	39715868	17	-	28162770	HEL	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	1.2696149744549077	[146]	[226]	9	hSpCas9	negative selection	11675217
39715795	39715818	17	+	28162770	HEL	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.15843221843387484	[290]	[166]	-1	hSpCas9	negative selection	11675218
39723436	39723459	17	+	28162770	HEL	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.35726116799964314	[111]	[55]	-3	hSpCas9	negative selection	11675219
39708378	39708401	17	-	28162770	HEL	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	-0.2360954784771859	[330]	[179]	-2	hSpCas9	negative selection	11675220
39708472	39708495	17	-	28162770	HEL	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	0.2385896488642492	[175]	[132]	2	hSpCas9	negative selection	11675221
39710357	39710380	17	-	28162770	HEL	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.5783648933675186	[372]	[159]	-4	hSpCas9	negative selection	11675222
39710418	39710441	17	+	28162770	HEL	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.43088403114282303	[401]	[190]	-3	hSpCas9	negative selection	11675223
39711994	39712017	17	+	28162770	HEL	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-0.48449635629575083	[307]	[140]	-3	hSpCas9	negative selection	11675224
39715307	39715330	17	-	28162770	HEL	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	0.057776331279200566	[14]	[9]	0	hSpCas9	negative selection	11675225
39715486	39715509	17	-	28162770	HEL	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.9841654317941076	[348]	[112]	-6	hSpCas9	negative selection	11675226
39715845	39715868	17	-	28162770	MV411	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	-0.8105097984265042	[126]	[60]	-5	hSpCas9	negative selection	11844583
39715795	39715818	17	+	28162770	MV411	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.32402910745415786	[265]	[178]	-2	hSpCas9	negative selection	11844584
39723436	39723459	17	+	28162770	MV411	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.7013371258620515	[82]	[42]	-5	hSpCas9	negative selection	11844585
39708378	39708401	17	-	28162770	MV411	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	-0.24800803221245749	[288]	[204]	-2	hSpCas9	negative selection	11844586
39708472	39708495	17	-	28162770	MV411	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.10557822188868404	[128]	[100]	-1	hSpCas9	negative selection	11844587
39710357	39710380	17	-	28162770	MV411	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.5611659174720878	[288]	[164]	-4	hSpCas9	negative selection	11844588
39710418	39710441	17	+	28162770	MV411	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.6262459994358244	[305]	[166]	-4	hSpCas9	negative selection	11844589
39711994	39712017	17	+	28162770	MV411	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-1.4096747356942163	[245]	[77]	-7	hSpCas9	negative selection	11844590
39715307	39715330	17	-	28162770	MV411	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	2.852299608941636	[11]	[72]	9	hSpCas9	negative selection	11844591
39715486	39715509	17	-	28162770	MV411	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	0.6723228360179662	[218]	[293]	6	hSpCas9	negative selection	11844592
39715845	39715868	17	-	28162770	MONOMAC1	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.21800065221929016	[74]	[99]	2	hSpCas9	negative selection	12013949
39715795	39715818	17	+	28162770	MONOMAC1	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	0.6454218759539663	[144]	[259]	6	hSpCas9	negative selection	12013950
39723436	39723459	17	+	28162770	MONOMAC1	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-1.1727893008128765	[58]	[29]	-7	hSpCas9	negative selection	12013951
39708378	39708401	17	-	28162770	MONOMAC1	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.42603025868710476	[136]	[210]	4	hSpCas9	negative selection	12013952
39708472	39708495	17	-	28162770	MONOMAC1	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-1.054078893217511	[95]	[52]	-7	hSpCas9	negative selection	12013953
39710357	39710380	17	-	28162770	MONOMAC1	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	0.3323840901775178	[202]	[292]	3	hSpCas9	negative selection	12013954
39710418	39710441	17	+	28162770	MONOMAC1	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	0.06917180656938382	[226]	[272]	0	hSpCas9	negative selection	12013955
39711994	39712017	17	+	28162770	MONOMAC1	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-0.2641510429180905	[153]	[146]	-2	hSpCas9	negative selection	12013956
39715307	39715330	17	-	28162770	MONOMAC1	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-0.13563630239541036	[22]	[23]	-1	hSpCas9	negative selection	12013957
39715486	39715509	17	-	28162770	MONOMAC1	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.2221278280223839	[173]	[170]	-2	hSpCas9	negative selection	12013958
39715845	39715868	17	-	28162770	OCIAML2	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	0.05090729533736131	[30]	[177]	0	hSpCas9	negative selection	12183315
39715795	39715818	17	+	28162770	OCIAML2	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	0.7449670345854337	[37]	[352]	7	hSpCas9	negative selection	12183316
39723436	39723459	17	+	28162770	OCIAML2	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.085965975006836	[8]	[46]	0	hSpCas9	negative selection	12183317
39708378	39708401	17	-	28162770	OCIAML2	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.3136414837024016	[44]	[309]	3	hSpCas9	negative selection	12183318
39708472	39708495	17	-	28162770	OCIAML2	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.4431490888200544	[25]	[105]	-3	hSpCas9	negative selection	12183319
39710357	39710380	17	-	28162770	OCIAML2	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	-0.39835953875199914	[72]	[306]	-3	hSpCas9	negative selection	12183320
39710418	39710441	17	+	28162770	OCIAML2	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.5417129233036438	[51]	[197]	-4	hSpCas9	negative selection	12183321
39711994	39712017	17	+	28162770	OCIAML2	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	0.33233332769828516	[46]	[327]	3	hSpCas9	negative selection	12183322
39715307	39715330	17	-	28162770	OCIAML2	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-1.470629825242161	[4]	[9]	-7	hSpCas9	negative selection	12183323
39715486	39715509	17	-	28162770	OCIAML2	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-0.8517199925976674	[41]	[128]	-5	hSpCas9	negative selection	12183324
39715845	39715868	17	-	28162770	OCIAML3	viability	GCACCGTGTGCACGAAGCAGAGG	ERBB2	ENSG00000141736	-1.162291399898689	[42]	[57]	-7	hSpCas9	negative selection	12352681
39715795	39715818	17	+	28162770	OCIAML3	viability	TCACTGAGGGAACTGGGCAGTGG	ERBB2	ENSG00000141736	-0.1651643415202888	[64]	[174]	-1	hSpCas9	negative selection	12352682
39723436	39723459	17	+	28162770	OCIAML3	viability	GAGACTGCTGCAGGAAACGGAGG	ERBB2	ENSG00000141736	-0.5940076403241632	[20]	[41]	-4	hSpCas9	negative selection	12352683
39708378	39708401	17	-	28162770	OCIAML3	viability	ACAATCCGCAGCCTCTGCAGTGG	ERBB2	ENSG00000141736	0.5860273887629903	[78]	[357]	5	hSpCas9	negative selection	12352684
39708472	39708495	17	-	28162770	OCIAML3	viability	GGAGGCCCCTGTGACAGGGGTGG	ERBB2	ENSG00000141736	-0.8812895924046341	[35]	[58]	-6	hSpCas9	negative selection	12352685
39710357	39710380	17	-	28162770	OCIAML3	viability	GCAGCTCACAGATGCCACTGTGG	ERBB2	ENSG00000141736	0.13181739623684274	[77]	[257]	1	hSpCas9	negative selection	12352686
39710418	39710441	17	+	28162770	OCIAML3	viability	GAGTCCATGCCCAATCCCGAGGG	ERBB2	ENSG00000141736	-0.09246114779064463	[88]	[251]	0	hSpCas9	negative selection	12352687
39711994	39712017	17	+	28162770	OCIAML3	viability	CAGCAGAGGATGGAACACAGCGG	ERBB2	ENSG00000141736	-0.4420045468791132	[89]	[199]	-3	hSpCas9	negative selection	12352688
39715307	39715330	17	-	28162770	OCIAML3	viability	GGAGCTGCTCTGGCTGGAGCGGG	ERBB2	ENSG00000141736	-3.17897014104532	[2]	[0]	-9	hSpCas9	negative selection	12352689
39715486	39715509	17	-	28162770	OCIAML3	viability	GCAGGTTCTGGAAGACGCTGAGG	ERBB2	ENSG00000141736	-1.0764004074047717	[94]	[135]	-6	hSpCas9	negative selection	12352690