Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2069
• Symbol:EREG
• Description:epiregulin

DataSource: http://genomecrispr.dkfz.de/#!/results/EREG

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
74365313	74365336	4	-	26472758	Jiyoye	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	0.28431863372034005	[391]	[359]	2	hSpCas9	negative selection	51454
74379470	74379493	4	-	26472758	Jiyoye	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	-0.5141126424800859	[213]	[112]	-4	hSpCas9	negative selection	51455
74381031	74381054	4	-	26472758	Jiyoye	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.7422135587194972	[240]	[303]	5	hSpCas9	negative selection	51456
74381116	74381139	4	+	26472758	Jiyoye	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-1.5314240738299831	[137]	[35]	-7	hSpCas9	negative selection	51457
74365296	74365319	4	+	26472758	Jiyoye	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.4508056136216987	[115]	[63]	-3	hSpCas9	negative selection	51458
74365329	74365352	4	+	26472758	Jiyoye	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.44082152504907657	[125]	[69]	-3	hSpCas9	negative selection	51459
74365354	74365377	4	-	26472758	Jiyoye	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	1.9921378822270293	[24]	[74]	8	hSpCas9	negative selection	51460
74379489	74379512	4	-	26472758	Jiyoye	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.4660690705594419	[71]	[74]	3	hSpCas9	negative selection	51461
74381093	74381116	4	+	26472758	Jiyoye	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.4992677974326336	[402]	[214]	-4	hSpCas9	negative selection	51462
74381018	74381041	4	+	26472758	Jiyoye	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	0.10761509964696536	[255]	[207]	0	hSpCas9	negative selection	51463
74365313	74365336	4	-	26472758	KBM7	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	0.1446503282688263	[2109,1668]	[1292,690]	1	hSpCas9	negative selection	242572
74379470	74379493	4	-	26472758	KBM7	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.24964027003304107	[651,521]	[353,300]	2	hSpCas9	negative selection	242573
74381031	74381054	4	-	26472758	KBM7	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3784104212806163	[1438,1223]	[1064,583]	4	hSpCas9	negative selection	242574
74381116	74381139	4	+	26472758	KBM7	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.9517830704062448	[134,193]	[245,69]	9	hSpCas9	negative selection	242575
74365296	74365319	4	+	26472758	KBM7	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.8915743600178181	[205,139]	[144,151]	8	hSpCas9	negative selection	242576
74365329	74365352	4	+	26472758	KBM7	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.3226863883295955	[423,151]	[161,161]	3	hSpCas9	negative selection	242577
74365354	74365377	4	-	26472758	KBM7	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	0.3126712455773507	[233,218]	[151,114]	3	hSpCas9	negative selection	242578
74379489	74379512	4	-	26472758	KBM7	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.4508178875446759	[486,710]	[418,371]	5	hSpCas9	negative selection	242579
74381093	74381116	4	+	26472758	KBM7	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	0.06417022583069376	[1427,1397]	[796,607]	0	hSpCas9	negative selection	242580
74381018	74381041	4	+	26472758	KBM7	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.17336948916328043	[1254,944]	[420,483]	-2	hSpCas9	negative selection	242581
74365313	74365336	4	-	26472758	Raji	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.13044553057051655	[782]	[165]	-1	hSpCas9	negative selection	433690
74379470	74379493	4	-	26472758	Raji	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.585846414794077	[266]	[92]	5	hSpCas9	negative selection	433691
74381031	74381054	4	-	26472758	Raji	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.37644172883516336	[477]	[143]	3	hSpCas9	negative selection	433692
74381116	74381139	4	+	26472758	Raji	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.10738353537359968	[51]	[12]	1	hSpCas9	negative selection	433693
74365296	74365319	4	+	26472758	Raji	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	1.9486857893545415	[47]	[42]	9	hSpCas9	negative selection	433694
74365329	74365352	4	+	26472758	Raji	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.32538418759288984	[140]	[40]	3	hSpCas9	negative selection	433695
74365354	74365377	4	-	26472758	Raji	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-1.2571888969222567	[102]	[9]	-7	hSpCas9	negative selection	433696
74379489	74379512	4	-	26472758	Raji	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-0.01140261707691198	[290]	[66]	0	hSpCas9	negative selection	433697
74381093	74381116	4	+	26472758	Raji	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.27493523137904075	[682]	[130]	-2	hSpCas9	negative selection	433698
74381018	74381041	4	+	26472758	Raji	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.40102546204635914	[733]	[128]	-3	hSpCas9	negative selection	433699
74365313	74365336	4	-	26472758	K562	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.4707699241045078	[1314]	[800]	-3	hSpCas9	negative selection	624808
74379470	74379493	4	-	26472758	K562	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.48751428644690975	[424]	[502]	4	hSpCas9	negative selection	624809
74381031	74381054	4	-	26472758	K562	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.6073116298407966	[992]	[1276]	5	hSpCas9	negative selection	624810
74381116	74381139	4	+	26472758	K562	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	1.359021849306303	[126]	[274]	9	hSpCas9	negative selection	624811
74365296	74365319	4	+	26472758	K562	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.2768402053588245	[175]	[179]	2	hSpCas9	negative selection	624812
74365329	74365352	4	+	26472758	K562	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.6530012048079912	[167]	[445]	9	hSpCas9	negative selection	624813
74365354	74365377	4	-	26472758	K562	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	0.6837037731919682	[117]	[159]	5	hSpCas9	negative selection	624814
74379489	74379512	4	-	26472758	K562	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	1.006602264529786	[430]	[730]	8	hSpCas9	negative selection	624815
74381093	74381116	4	+	26472758	K562	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	0.25833347424507447	[1134]	[1145]	2	hSpCas9	negative selection	624816
74381018	74381041	4	+	26472758	K562	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	0.459671288883033	[925]	[1074]	3	hSpCas9	negative selection	624817
74365297	74365320	4	+	26627737	DLD1	viability	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.9270608929505497	[1144]	[196,217,155]	-7	hSpCas9	negative selection	825774
74365328	74365351	4	+	26627737	DLD1	viability	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.5716596225944643	[178]	[77,95,76]	6	hSpCas9	negative selection	825775
74365329	74365352	4	+	26627737	DLD1	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.21027544617369232	[274]	[91,108,97]	2	hSpCas9	negative selection	825776
74379452	74379475	4	-	26627737	DLD1	viability	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.10791056300892393	[552]	[270,196,103]	1	hSpCas9	negative selection	825777
74381031	74381054	4	-	26627737	DLD1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.1584344419633934	[597]	[139,220,146]	-2	hSpCas9	negative selection	825778
74365297	74365320	4	+	26627737	GBM cells	viability after 5 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.389066888078339	[419]	[174,168]	-6	hSpCas9	negative selection	908089
74365328	74365351	4	+	26627737	GBM cells	viability after 5 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.49729689136916333	[106]	[75,85]	7	hSpCas9	negative selection	908090
74365329	74365352	4	+	26627737	GBM cells	viability after 5 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.4772346109995633	[121]	[32,60]	-6	hSpCas9	negative selection	908091
74379452	74379475	4	-	26627737	GBM cells	viability after 5 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.3490420386328914	[395]	[281,258]	5	hSpCas9	negative selection	908092
74381031	74381054	4	-	26627737	GBM cells	viability after 5 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.04643205024424428	[258]	[136,131]	0	hSpCas9	negative selection	908093
74365297	74365320	4	+	26627737	GBM cells	viability after 13 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.5214627916022677	[419]	[155,160]	-6	hSpCas9	negative selection	990404
74365328	74365351	4	+	26627737	GBM cells	viability after 13 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.554761718859353	[106]	[92,78]	7	hSpCas9	negative selection	990405
74365329	74365352	4	+	26627737	GBM cells	viability after 13 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.2705570844490808	[121]	[82,31]	-3	hSpCas9	negative selection	990406
74379452	74379475	4	-	26627737	GBM cells	viability after 13 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.5080181178601255	[395]	[379,244]	6	hSpCas9	negative selection	990407
74381031	74381054	4	-	26627737	GBM cells	viability after 13 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.25818043526121615	[258]	[161,172]	3	hSpCas9	negative selection	990408
74365297	74365320	4	+	26627737	GBM cells	viability after 21 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.2938195874493305	[419]	[182,188]	-3	hSpCas9	negative selection	1072719
74365328	74365351	4	+	26627737	GBM cells	viability after 21 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-0.1512691664472421	[106]	[55,48]	-1	hSpCas9	negative selection	1072720
74365329	74365352	4	+	26627737	GBM cells	viability after 21 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.6257312120656666	[121]	[21,20]	-8	hSpCas9	negative selection	1072721
74379452	74379475	4	-	26627737	GBM cells	viability after 21 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.6497628528373416	[395]	[324,348]	6	hSpCas9	negative selection	1072722
74381031	74381054	4	-	26627737	GBM cells	viability after 21 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.09053282758363985	[258]	[153,145]	0	hSpCas9	negative selection	1072723
74365297	74365320	4	+	26627737	RPE1	viability after 9 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.07541927743132804	[1816]	[445,660]	0	hSpCas9	negative selection	1155034
74365328	74365351	4	+	26627737	RPE1	viability after 9 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	1.1583896829325357	[440]	[298,319]	7	hSpCas9	negative selection	1155035
74365329	74365352	4	+	26627737	RPE1	viability after 9 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.6765236852137966	[131]	[87,188]	8	hSpCas9	negative selection	1155036
74379452	74379475	4	-	26627737	RPE1	viability after 9 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.7212365967381638	[838]	[322,574]	5	hSpCas9	negative selection	1155037
74381031	74381054	4	-	26627737	RPE1	viability after 9 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.0164178668604157	[847]	[247,294]	0	hSpCas9	negative selection	1155038
74365297	74365320	4	+	26627737	RPE1	viability after 12 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.33728000861256713	[1816]	[331,443]	-2	hSpCas9	negative selection	1237349
74365328	74365351	4	+	26627737	RPE1	viability after 12 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.8347230585748467	[440]	[289,127]	5	hSpCas9	negative selection	1237350
74365329	74365352	4	+	26627737	RPE1	viability after 12 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.9032758409363795	[131]	[154,108]	8	hSpCas9	negative selection	1237351
74379452	74379475	4	-	26627737	RPE1	viability after 12 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.6446545252663657	[838]	[314,391]	4	hSpCas9	negative selection	1237352
74381031	74381054	4	-	26627737	RPE1	viability after 12 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.12721369525765794	[847]	[313,96]	-1	hSpCas9	negative selection	1237353
74365297	74365320	4	+	26627737	RPE1	viability after 15 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.7748791336452769	[1816]	[1162,605]	5	hSpCas9	negative selection	1319664
74365328	74365351	4	+	26627737	RPE1	viability after 15 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.9363547407544474	[440]	[281,196]	5	hSpCas9	negative selection	1319665
74365329	74365352	4	+	26627737	RPE1	viability after 15 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.6996667097720184	[131]	[104,136]	8	hSpCas9	negative selection	1319666
74379452	74379475	4	-	26627737	RPE1	viability after 15 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.9643722175544889	[838]	[682,250]	6	hSpCas9	negative selection	1319667
74381031	74381054	4	-	26627737	RPE1	viability after 15 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.10651634916059041	[847]	[317,130]	0	hSpCas9	negative selection	1319668
74365297	74365320	4	+	26627737	RPE1	viability after 18 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.36749043322912334	[1816]	[591,675]	2	hSpCas9	negative selection	1401979
74365328	74365351	4	+	26627737	RPE1	viability after 18 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.7260783593739076	[440]	[221,169]	4	hSpCas9	negative selection	1401980
74365329	74365352	4	+	26627737	RPE1	viability after 18 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	2.7306090831217142	[131]	[190,284]	9	hSpCas9	negative selection	1401981
74379452	74379475	4	-	26627737	RPE1	viability after 18 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.6236170229419097	[838]	[329,368]	4	hSpCas9	negative selection	1401982
74381031	74381054	4	-	26627737	RPE1	viability after 18 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.4419923687411487	[847]	[210,122]	-3	hSpCas9	negative selection	1401983
74365297	74365320	4	+	26627737	HeLa	viability after 8 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.09093080007709031	[498]	[405,135,192]	0	hSpCas9	negative selection	1484294
74365328	74365351	4	+	26627737	HeLa	viability after 8 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.04737513490203993	[172]	[96,127,16]	0	hSpCas9	negative selection	1484295
74365329	74365352	4	+	26627737	HeLa	viability after 8 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.2940947183030869	[288]	[92,47,23]	-8	hSpCas9	negative selection	1484296
74379452	74379475	4	-	26627737	HeLa	viability after 8 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.18629641252413742	[637]	[585,251,178]	1	hSpCas9	negative selection	1484297
74381031	74381054	4	-	26627737	HeLa	viability after 8 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.07697616342706587	[296]	[156,171,87]	0	hSpCas9	negative selection	1484298
74365297	74365320	4	+	26627737	HeLa	viability after 12 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.02270103714816102	[498]	[509,50,92]	0	hSpCas9	negative selection	1566609
74365328	74365351	4	+	26627737	HeLa	viability after 12 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-1.3039764595552634	[172]	[65,18,3]	-8	hSpCas9	negative selection	1566610
74365329	74365352	4	+	26627737	HeLa	viability after 12 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.7774297724579724	[288]	[6,99,96]	-6	hSpCas9	negative selection	1566611
74379452	74379475	4	-	26627737	HeLa	viability after 12 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.1202562295066103	[637]	[190,257,410]	1	hSpCas9	negative selection	1566612
74381031	74381054	4	-	26627737	HeLa	viability after 12 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.39947948162086017	[296]	[234,112,144]	3	hSpCas9	negative selection	1566613
74365297	74365320	4	+	26627737	HeLa	viability after 15 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.9937200367011607	[498]	[89,19,203]	-7	hSpCas9	negative selection	1648924
74365328	74365351	4	+	26627737	HeLa	viability after 15 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-1.2644027488958616	[172]	[10,25,52]	-8	hSpCas9	negative selection	1648925
74365329	74365352	4	+	26627737	HeLa	viability after 15 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.4318263281410664	[288]	[43,28,58]	-8	hSpCas9	negative selection	1648926
74379452	74379475	4	-	26627737	HeLa	viability after 15 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-0.23231522101815083	[637]	[187,190,289]	-2	hSpCas9	negative selection	1648927
74381031	74381054	4	-	26627737	HeLa	viability after 15 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.4926530815950839	[296]	[157,67,293]	4	hSpCas9	negative selection	1648928
74365297	74365320	4	+	26627737	HeLa	viability after 18 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.9369472442072408	[498]	[67,16,203]	-7	hSpCas9	negative selection	1731239
74365328	74365351	4	+	26627737	HeLa	viability after 18 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-1.2443938619523556	[172]	[6,22,52]	-8	hSpCas9	negative selection	1731240
74365329	74365352	4	+	26627737	HeLa	viability after 18 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.5474440672449987	[288]	[22,23,58]	-8	hSpCas9	negative selection	1731241
74379452	74379475	4	-	26627737	HeLa	viability after 18 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-0.24398307185536505	[637]	[121,158,289]	-2	hSpCas9	negative selection	1731242
74381031	74381054	4	-	26627737	HeLa	viability after 18 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.4704337300119743	[296]	[101,54,293]	4	hSpCas9	negative selection	1731243
74365297	74365320	4	+	26627737	HCT116	viability after 6 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	2.922501158154682	[615]	[467,880]	9	hSpCas9	negative selection	1813554
74365328	74365351	4	+	26627737	HCT116	viability after 6 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.9551290932004015	[354]	[249,29]	5	hSpCas9	negative selection	1813555
74365329	74365352	4	+	26627737	HCT116	viability after 6 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.5153243482836618	[270]	[338,1]	7	hSpCas9	negative selection	1813556
74379452	74379475	4	-	26627737	HCT116	viability after 6 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-0.4950479718509295	[1169]	[290,41]	-3	hSpCas9	negative selection	1813557
74381031	74381054	4	-	26627737	HCT116	viability after 6 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.24741267977370918	[633]	[43,105]	-1	hSpCas9	negative selection	1813558
74365297	74365320	4	+	26627737	HCT116	viability after 8 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.17492698446964294	[433]	[166,281,357]	2	hSpCas9	negative selection	1895869
74365328	74365351	4	+	26627737	HCT116	viability after 8 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-0.13684440098211176	[326]	[145,154,189]	-1	hSpCas9	negative selection	1895870
74365329	74365352	4	+	26627737	HCT116	viability after 8 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.5837160687882399	[99]	[96,67,82]	6	hSpCas9	negative selection	1895871
74379452	74379475	4	-	26627737	HCT116	viability after 8 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.3748378071512939	[440]	[289,351,302]	4	hSpCas9	negative selection	1895872
74381031	74381054	4	-	26627737	HCT116	viability after 8 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.7807479500282006	[413]	[158,121,117]	-7	hSpCas9	negative selection	1895873
74365297	74365320	4	+	26627737	HCT116	viability after 9 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	1.0136341324121279	[615]	[397,279]	7	hSpCas9	negative selection	1978184
74365328	74365351	4	+	26627737	HCT116	viability after 9 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-1.2886336611468234	[354]	[54,25]	-7	hSpCas9	negative selection	1978185
74365329	74365352	4	+	26627737	HCT116	viability after 9 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.4735691102031285	[270]	[167,226]	8	hSpCas9	negative selection	1978186
74379452	74379475	4	-	26627737	HCT116	viability after 9 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-1.1930707380928909	[1169]	[120,148]	-7	hSpCas9	negative selection	1978187
74381031	74381054	4	-	26627737	HCT116	viability after 9 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-1.2224544670793132	[633]	[114,38]	-7	hSpCas9	negative selection	1978188
74365297	74365320	4	+	26627737	HCT116	viability after 12 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.03486471372085925	[433]	[176,308,187]	0	hSpCas9	negative selection	2060499
74365328	74365351	4	+	26627737	HCT116	viability after 12 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-0.39680954998082374	[326]	[141,65,180]	-4	hSpCas9	negative selection	2060500
74365329	74365352	4	+	26627737	HCT116	viability after 12 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.5026799605562946	[99]	[92,38,316]	9	hSpCas9	negative selection	2060501
74379452	74379475	4	-	26627737	HCT116	viability after 12 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-0.2193427667075626	[440]	[119,233,250]	-2	hSpCas9	negative selection	2060502
74381031	74381054	4	-	26627737	HCT116	viability after 12 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.18672263599711442	[413]	[211,164,193]	-2	hSpCas9	negative selection	2060503
74365297	74365320	4	+	26627737	HCT116	viability after 15 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.36286657373228326	[433]	[404,258,307]	3	hSpCas9	negative selection	2142814
74365328	74365351	4	+	26627737	HCT116	viability after 15 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-0.6623108962845365	[326]	[146,57,153]	-6	hSpCas9	negative selection	2142815
74365329	74365352	4	+	26627737	HCT116	viability after 15 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.45569731172618244	[99]	[99,70,67]	4	hSpCas9	negative selection	2142816
74379452	74379475	4	-	26627737	HCT116	viability after 15 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.15642403106025293	[440]	[259,210,371]	1	hSpCas9	negative selection	2142817
74381031	74381054	4	-	26627737	HCT116	viability after 15 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.6060822486340988	[413]	[195,166,110]	-6	hSpCas9	negative selection	2142818
74365297	74365320	4	+	26627737	HCT116	viability after 18 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.627728896452712	[433]	[301,286,388]	5	hSpCas9	negative selection	2225129
74365328	74365351	4	+	26627737	HCT116	viability after 18 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-0.5742548002289586	[326]	[158,11,155]	-5	hSpCas9	negative selection	2225130
74365329	74365352	4	+	26627737	HCT116	viability after 18 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.695697625041216	[99]	[199,102,170]	9	hSpCas9	negative selection	2225131
74379452	74379475	4	-	26627737	HCT116	viability after 18 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.2606281353901234	[440]	[229,267,267]	2	hSpCas9	negative selection	2225132
74381031	74381054	4	-	26627737	HCT116	viability after 18 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.4320323565954332	[413]	[514,212,76]	3	hSpCas9	negative selection	2225133
74365296	74365319	4	+	24336569	HL60	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.5899779208177279	[517]	[1649]	5	hSpCas9	negative selection	2263192
74365324	74365347	4	+	24336569	HL60	viability	AGGATGGAGATGCTCTGTGCCGG	EREG	ENSG00000124882	0.13641412403634368	[1508]	[3509]	1	hSpCas9	negative selection	2263193
74365329	74365352	4	+	24336569	HL60	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.4507569380202867	[64]	[375]	8	hSpCas9	negative selection	2263194
74365353	74365376	4	-	24336569	HL60	viability	CCAGGCAGAGCAGCAGCGCAGGG	EREG	ENSG00000124882	-1.179867804689891	[272]	[254]	-8	hSpCas9	negative selection	2263195
74379443	74379466	4	+	24336569	HL60	viability	AATAGGTTTCCATCTTCTACAGG	EREG	ENSG00000124882	-0.08310819771952135	[438]	[876]	0	hSpCas9	negative selection	2263196
74379452	74379475	4	-	24336569	HL60	viability	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-0.5131803410543706	[434]	[644]	-4	hSpCas9	negative selection	2263197
74379470	74379493	4	-	24336569	HL60	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.5496685815251858	[573]	[1777]	5	hSpCas9	negative selection	2263198
74379483	74379506	4	+	24336569	HL60	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.4857351690386701	[533]	[806]	-4	hSpCas9	negative selection	2263199
74379489	74379512	4	-	24336569	HL60	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.1582257333516307	[757]	[1789]	1	hSpCas9	negative selection	2263200
74379500	74379523	4	-	24336569	HL60	viability	AGTTATCACTGGACTCTCCTGGG	EREG	ENSG00000124882	-0.1838258182585742	[364]	[679]	-1	hSpCas9	negative selection	2263201
74365296	74365319	4	+	24336569	KBM7	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.35198325198401226	[662]	[2307]	3	hSpCas9	negative selection	2330369
74365324	74365347	4	+	24336569	KBM7	viability	AGGATGGAGATGCTCTGTGCCGG	EREG	ENSG00000124882	-0.3787571638044449	[1227]	[2575]	-3	hSpCas9	negative selection	2330370
74365329	74365352	4	+	24336569	KBM7	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.31489671334506064	[108]	[238]	-3	hSpCas9	negative selection	2330371
74365353	74365376	4	-	24336569	KBM7	viability	CCAGGCAGAGCAGCAGCGCAGGG	EREG	ENSG00000124882	1.5556375161346605	[55]	[448]	9	hSpCas9	negative selection	2330372
74379443	74379466	4	+	24336569	KBM7	viability	AATAGGTTTCCATCTTCTACAGG	EREG	ENSG00000124882	0.19469198713590857	[254]	[795]	1	hSpCas9	negative selection	2330373
74379452	74379475	4	-	24336569	KBM7	viability	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.42031726744377235	[239]	[875]	4	hSpCas9	negative selection	2330374
74379470	74379493	4	-	24336569	KBM7	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	-0.1702740930821478	[787]	[1909]	-1	hSpCas9	negative selection	2330375
74379483	74379506	4	+	24336569	KBM7	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.7599030093791477	[523]	[843]	-5	hSpCas9	negative selection	2330376
74379489	74379512	4	-	24336569	KBM7	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.27668234158382254	[364]	[1205]	2	hSpCas9	negative selection	2330377
74379500	74379523	4	-	24336569	KBM7	viability	AGTTATCACTGGACTCTCCTGGG	EREG	ENSG00000124882	-0.5499210117796846	[532]	[992]	-4	hSpCas9	negative selection	2330378
74381031	74381054	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.239401167789457	[4,4]	[3,2]	-3	hSpCas9	positive selection	2986264
74365313	74365336	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.4376717199284672	[4,4]	[2,1]	-6	hSpCas9	positive selection	2986265
74365297	74365320	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.8945198755975217	[3,3]	[2,0]	-8	hSpCas9	positive selection	2986266
74365299	74365322	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCCATCGCCGATGACCGCGGGG	EREG	ENSG00000124882	-0.9064172505132035	[2,3]	[1,0]	-8	hSpCas9	positive selection	2986267
74381031	74381054	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.38206168506308824	[4,4]	[4,4]	6	hSpCas9	positive selection	3054122
74365313	74365336	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.6892801279740406	[4,4]	[2,0]	-8	hSpCas9	positive selection	3054123
74365297	74365320	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.4283067223698824	[3,3]	[3,3]	7	hSpCas9	positive selection	3054124
74365299	74365322	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCCATCGCCGATGACCGCGGGG	EREG	ENSG00000124882	-0.5759573474075987	[2,2]	[2,0]	-7	hSpCas9	positive selection	3054125
74381031	74381054		-	24336571	A375	resistance to PLX after 7 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.2553194772785623	[10,11]	[12,13]	7	hSpCas9	positive selection	3112431
74381090	74381113		+	24336571	A375	resistance to PLX after 7 days	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.13817723908777602	[35,39]	[33,34]	-4	hSpCas9	positive selection	3112433
74379483	74379506		+	24336571	A375	resistance to PLX after 7 days	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.312367939518992	[23,21]	[29,27]	8	hSpCas9	positive selection	3112434
74381031	74381054		-	24336571	A375	resistance to PLX after 14 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.1253454188054211	[11,14]	[7,4]	1	hSpCas9	positive selection	3170224
74381090	74381113		+	24336571	A375	resistance to PLX after 14 days	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.4471091618910905	[31,46]	[11,13]	-5	hSpCas9	positive selection	3170226
74379483	74379506		+	24336571	A375	resistance to PLX after 14 days	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	1.302994482279208	[25,18]	[22,28]	8	hSpCas9	positive selection	3170227
74381031	74381054		-	24336571	A375	viability after 7 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.07846162159990966	[10]	[10,11]	1	hSpCas9	negative selection	3228017
74381090	74381113		+	24336571	A375	viability after 7 days	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.33831202473109734	[31]	[35,39]	5	hSpCas9	negative selection	3228019
74379483	74379506		+	24336571	A375	viability after 7 days	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.014539695255901819	[24]	[23,21]	0	hSpCas9	negative selection	3228020
74381031	74381054		-	24336571	A375	viability after 14 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3052537972167297	[10]	[11,14]	4	hSpCas9	negative selection	3285810
74381090	74381113		+	24336571	A375	viability after 14 days	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.40057189362988344	[31]	[31,46]	5	hSpCas9	negative selection	3285812
74379483	74379506		+	24336571	A375	viability after 14 days	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.042166540250768936	[24]	[25,18]	0	hSpCas9	negative selection	3285813
74384797	74384820	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	1.4249325657844893	[53,59]	[0,0]	6	hSpCas9	positive selection	3348281
74381090	74381113	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-1.2073730167291443	[320,385]	[0,0]	-7	hSpCas9	positive selection	3348282
74382748	74382771	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	9.006887833027166	[310,285]	[2004,2]	9	hSpCas9	positive selection	3348283
74381031	74381054	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-1.037294537445792	[313,313]	[0,0]	-7	hSpCas9	positive selection	3367492
74379483	74379506	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.7654731151161606	[89,89]	[0,0]	4	hSpCas9	positive selection	3367493
74379511	74379534	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	1.3808092648808354	[234,234]	[3,3]	6	hSpCas9	positive selection	3367494
74381031	74381054	4	-	26780180	HT29	viability (Avana library 4 designs)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.056553754897537	[]	[]	0	hSpCas9	negative selection	3423089
74365313	74365336	4	-	26780180	HT29	viability (Avana library 4 designs)	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	1.50326087881456	[]	[]	6	hSpCas9	negative selection	3423090
74365296	74365319	4	+	26780180	HT29	viability (Avana library 4 designs)	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.256287550182024	[]	[]	-4	hSpCas9	negative selection	3423091
74365298	74365321	4	+	26780180	HT29	viability (Avana library 4 designs)	TCCCATCGCCGATGACCGCGGGG	EREG	ENSG00000124882	0.767061762919337	[]	[]	3	hSpCas9	negative selection	3423092
74365296	74365319	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	4.69873427025236	[]	[]	7	hSpCas9	negative selection	3504070
74365313	74365336	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-1.68600546369215	[]	[]	-2	hSpCas9	negative selection	3504071
74365298	74365321	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCATCGCCGATGACCGCGGGG	EREG	ENSG00000124882	6.79080814365282	[]	[]	9	hSpCas9	negative selection	3504072
74381031	74381054	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	2.47776187369052	[]	[]	3	hSpCas9	negative selection	3504073
74379489	74379512	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.722436296136494	[]	[]	1	hSpCas9	negative selection	3504074
74381090	74381113	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	5.11777955825037	[]	[]	8	hSpCas9	negative selection	3504075
74365296	74365319	4	+	26780180	A375	viability (Avana lentiGuide)	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	1.35985856267706	[]	[]	1	hSpCas9	negative selection	3612729
74365313	74365336	4	-	26780180	A375	viability (Avana lentiGuide)	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	19.2036766866824	[]	[]	8	hSpCas9	negative selection	3612730
74365298	74365321	4	+	26780180	A375	viability (Avana lentiGuide)	TCCCATCGCCGATGACCGCGGGG	EREG	ENSG00000124882	-0.449840884476976	[]	[]	0	hSpCas9	negative selection	3612731
74381031	74381054	4	-	26780180	A375	viability (Avana lentiGuide)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-2.77498491841714	[]	[]	-5	hSpCas9	negative selection	3612732
74379489	74379512	4	-	26780180	A375	viability (Avana lentiGuide)	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-1.20840732198117	[]	[]	-2	hSpCas9	negative selection	3612733
74381090	74381113	4	+	26780180	A375	viability (Avana lentiGuide)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-6.15518144738156	[]	[]	-9	hSpCas9	negative selection	3612734
74365296	74365319	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.22135071963872413	[5]	[6,6]	6	hSpCas9	positive selection	3721388
74365313	74365336	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.06221326425340348	[4]	[4,3]	-1	hSpCas9	positive selection	3721389
74365298	74365321	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCATCGCCGATGACCGCGGGG	EREG	ENSG00000124882	0.36007134477350283	[4]	[6,5]	9	hSpCas9	positive selection	3721390
74381031	74381054	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.23480419400524039	[5]	[6,6]	6	hSpCas9	positive selection	3721391
74379489	74379512	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-0.15826123742885442	[5]	[4,4]	-3	hSpCas9	positive selection	3721392
74381090	74381113	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.18930229820225228	[5]	[6,6]	5	hSpCas9	positive selection	3721393
74365296	74365319	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.44214004016459485	[5]	[3,2]	-5	hSpCas9	positive selection	3829995
74365313	74365336	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.764941831219364	[6]	[3,1]	-7	hSpCas9	positive selection	3829996
74365298	74365321	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCATCGCCGATGACCGCGGGG	EREG	ENSG00000124882	0.0024468307214073892	[5]	[3,4]	0	hSpCas9	positive selection	3829997
74381031	74381054	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.1784186189258025	[6]	[6,5]	4	hSpCas9	positive selection	3829998
74379489	74379512	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.1909009808196629	[4]	[4,4]	5	hSpCas9	positive selection	3829999
74381090	74381113	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.39426028037720384	[7]	[8,7]	9	hSpCas9	positive selection	3830000
74381031	74381054	4	-	26780180	A375	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.546283938511146	[]	[]	1	hSpCas9	negative selection	3937339
74384797	74384820	4	-	26780180	A375	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.937068466104943	[]	[]	4	hSpCas9	negative selection	3937340
74381090	74381113	4	+	26780180	A375	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.562932340607047	[]	[]	1	hSpCas9	negative selection	3937341
74379483	74379506	4	+	26780180	A375	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.742731932032867	[]	[]	2	hSpCas9	negative selection	3937342
74379511	74379534	4	-	26780180	A375	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.748497475743858	[]	[]	2	hSpCas9	negative selection	3937343
74382748	74382771	4	+	26780180	A375	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.59382692749785	[]	[]	1	hSpCas9	negative selection	3937344
74381031	74381054	4	-	26780180	HT29	viability (GeCKOv2 library)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.777975825781495	[]	[]	3	hSpCas9	negative selection	4045305
74384797	74384820	4	-	26780180	HT29	viability (GeCKOv2 library)	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	1.19649281542791	[]	[]	6	hSpCas9	negative selection	4045306
74381090	74381113	4	+	26780180	HT29	viability (GeCKOv2 library)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.46350201167798	[]	[]	1	hSpCas9	negative selection	4045307
74379483	74379506	4	+	26780180	HT29	viability (GeCKOv2 library)	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	1.15225063163796	[]	[]	5	hSpCas9	negative selection	4045308
74379511	74379534	4	-	26780180	HT29	viability (GeCKOv2 library)	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.733853825118212	[]	[]	3	hSpCas9	negative selection	4045309
74382748	74382771	4	+	26780180	HT29	viability (GeCKOv2 library)	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.89714307586115	[]	[]	4	hSpCas9	negative selection	4045310
74381031	74381054	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.1304897088453447	[3]	[1,2]	-3	hSpCas9	positive selection	4135161
74381090	74381113	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.14154210087689767	[4]	[3,3]	3	hSpCas9	positive selection	4135163
74379483	74379506	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.26363550577300837	[4]	[2,4]	6	hSpCas9	positive selection	4135164
74381031	74381054	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	1.0604425140609122	[3]	[1,2,3,3]	7	hSpCas9	positive selection	4199183
74381090	74381113	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.9267810282486767	[4]	[0,2,5,3]	6	hSpCas9	positive selection	4199185
74379483	74379506	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	1.361470596282903	[3]	[1,4,5,4]	9	hSpCas9	positive selection	4199186
74384797	74384820	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.09432555780946261	[1]	[2,0]	-2	hSpCas9	positive selection	4269147
74381090	74381113	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.07185433005638375	[4]	[4,2]	1	hSpCas9	positive selection	4269148
74382748	74382771	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.5037975352706978	[3]	[4,4]	9	hSpCas9	positive selection	4269149
74381031	74381054	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.34297278181852653	[3]	[2,3]	7	hSpCas9	positive selection	4333412
74379483	74379506	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.2344916880022293	[1]	[1,0]	-5	hSpCas9	positive selection	4333413
74379511	74379534	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.35652495018934216	[3]	[3,3]	7	hSpCas9	positive selection	4333414
74379484	74379506	4	+	27760321	OCIAML3	viability	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.2866392789060178	[362,343]	[357,310]	3	hSpCas9	negative selection	4398242
74379501	74379523	4	-	27760321	OCIAML3	viability	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.43075314311840507	[471,403]	[356,594]	5	hSpCas9	negative selection	4398243
74381031	74381053	4	-	27760321	OCIAML3	viability	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.5823399890390903	[693,614]	[742,793]	7	hSpCas9	negative selection	4398244
74381117	74381139	4	+	27760321	OCIAML3	viability	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.8092691222739424	[276,253]	[81,165]	-6	hSpCas9	negative selection	4398245
74382692	74382714	4	-	27760321	OCIAML3	viability	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	-0.36730693520763247	[256,212]	[130,155]	-4	hSpCas9	negative selection	4398246
74379484	74379506	4	+	27760321	OCIAML2	viability	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.2144023420449716	[362,343]	[200,306]	-3	hSpCas9	negative selection	4481705
74379501	74379523	4	-	27760321	OCIAML2	viability	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.7338370264897872	[471,403]	[397,836]	8	hSpCas9	negative selection	4481706
74381031	74381053	4	-	27760321	OCIAML2	viability	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3227585416227986	[693,614]	[582,763]	4	hSpCas9	negative selection	4481707
74381117	74381139	4	+	27760321	OCIAML2	viability	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.4051788590119926	[276,253]	[140,189]	-5	hSpCas9	negative selection	4481708
74382692	74382714	4	-	27760321	OCIAML2	viability	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.6113717750646385	[256,212]	[308,262]	8	hSpCas9	negative selection	4481709
74379484	74379506	4	+	27760321	MV411	viability	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.1869314821048781	[362,343]	[304,206]	1	hSpCas9	negative selection	4565168
74379501	74379523	4	-	27760321	MV411	viability	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.646634152452178	[471,403]	[80,1006]	5	hSpCas9	negative selection	4565169
74381031	74381053	4	-	27760321	MV411	viability	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	1.0125691487790283	[693,614]	[524,1387]	7	hSpCas9	negative selection	4565170
74381117	74381139	4	+	27760321	MV411	viability	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.048337559895193616	[276,253]	[150,196]	0	hSpCas9	negative selection	4565171
74382692	74382714	4	-	27760321	MV411	viability	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	-1.9425188594699536	[256,212]	[0,98]	-8	hSpCas9	negative selection	4565172
74379484	74379506	4	+	27760321	HL60	viability	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.003606914475262457	[362,343]	[266,310]	0	hSpCas9	negative selection	4648631
74379501	74379523	4	-	27760321	HL60	viability	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.1351764777234251	[471,403]	[365,418]	1	hSpCas9	negative selection	4648632
74381031	74381053	4	-	27760321	HL60	viability	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.4268853486318198	[693,614]	[635,803]	5	hSpCas9	negative selection	4648633
74381117	74381139	4	+	27760321	HL60	viability	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.7626804983245546	[276,253]	[120,134]	-7	hSpCas9	negative selection	4648634
74382692	74382714	4	-	27760321	HL60	viability	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.651518978307194	[256,212]	[207,397]	7	hSpCas9	negative selection	4648635
74379484	74379506	4	+	27760321	HT1080	viability	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.5137015632662407	[343,268]	[149,200]	2	hSpCas9	negative selection	4732094
74379501	74379523	4	-	27760321	HT1080	viability	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	1.1011985529248272	[403,314]	[332,278]	6	hSpCas9	negative selection	4732095
74381031	74381053	4	-	27760321	HT1080	viability	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.9643920448273582	[614,479]	[479,365]	5	hSpCas9	negative selection	4732096
74381117	74381139	4	+	27760321	HT1080	viability	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.37720743026465203	[253,197]	[146,83]	2	hSpCas9	negative selection	4732097
74382692	74382714	4	-	27760321	HT1080	viability	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.6179643517160998	[212,165]	[80,153]	3	hSpCas9	negative selection	4732098
74379484	74379506	4	+	27760321	HT29	viability after 7 days	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.8015560938939353	[343,268]	[294,266,128]	-8	hSpCas9	negative selection	4815557
74379501	74379523	4	-	27760321	HT29	viability after 7 days	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	-0.6612899754157489	[403,314]	[438,221,237]	-7	hSpCas9	negative selection	4815558
74381031	74381053	4	-	27760321	HT29	viability after 7 days	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3241702006865135	[614,479]	[1156,742,784]	5	hSpCas9	negative selection	4815559
74381117	74381139	4	+	27760321	HT29	viability after 7 days	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.07791995439513222	[253,197]	[380,236,311]	1	hSpCas9	negative selection	4815560
74382692	74382714	4	-	27760321	HT29	viability after 7 days	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	-0.11301740336364285	[212,165]	[331,206,153]	-2	hSpCas9	negative selection	4815561
74379484	74379506	4	+	27760321	HT29	viability after 25 days	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.10568591413639297	[343,268]	[340,284,351]	-1	hSpCas9	negative selection	4899020
74379501	74379523	4	-	27760321	HT29	viability after 25 days	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.07025169694290952	[403,314]	[471,367,452]	0	hSpCas9	negative selection	4899021
74381031	74381053	4	-	27760321	HT29	viability after 25 days	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.5225843518353428	[614,479]	[1236,570,861]	6	hSpCas9	negative selection	4899022
74381117	74381139	4	+	27760321	HT29	viability after 25 days	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.023813130566817442	[253,197]	[290,192,305]	0	hSpCas9	negative selection	4899023
74382692	74382714	4	-	27760321	HT29	viability after 25 days	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.4283529207859447	[212,165]	[168,295,430]	4	hSpCas9	negative selection	4899024
74379484	74379506	4	+	27760321	HT29	viability after 22 days	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.26855189295611237	[343,268]	[321,242,316]	-3	hSpCas9	negative selection	4982483
74379501	74379523	4	-	27760321	HT29	viability after 22 days	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	-0.03934314301605941	[403,314]	[245,613,356]	0	hSpCas9	negative selection	4982484
74381031	74381053	4	-	27760321	HT29	viability after 22 days	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.6813741246702034	[614,479]	[1023,982,1037]	7	hSpCas9	negative selection	4982485
74381117	74381139	4	+	27760321	HT29	viability after 22 days	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.6217430208866644	[253,197]	[399,404,400]	7	hSpCas9	negative selection	4982486
74382692	74382714	4	-	27760321	HT29	viability after 22 days	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.2662895037717482	[212,165]	[228,328,232]	2	hSpCas9	negative selection	4982487
74379484	74379506	4	+	27760321	HT29	viability after 19 days	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.2686405223389	[343,268]	[497,390,386]	2	hSpCas9	negative selection	5065946
74379501	74379523	4	-	27760321	HT29	viability after 19 days	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.7146279050718816	[403,314]	[372,675,932]	7	hSpCas9	negative selection	5065947
74381031	74381053	4	-	27760321	HT29	viability after 19 days	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.31044946301508314	[614,479]	[823,439,1058]	3	hSpCas9	negative selection	5065948
74381117	74381139	4	+	27760321	HT29	viability after 19 days	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.6240202559348679	[253,197]	[365,130,31]	-5	hSpCas9	negative selection	5065949
74382692	74382714	4	-	27760321	HT29	viability after 19 days	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.03431613251738441	[212,165]	[323,282,74]	0	hSpCas9	negative selection	5065950
74379484	74379506	4	+	27760321	HT29	viability after 16 days	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.2840924367910721	[343,268]	[309,438,492]	3	hSpCas9	negative selection	5149409
74379501	74379523	4	-	27760321	HT29	viability after 16 days	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.1489316578005646	[403,314]	[554,445,346]	1	hSpCas9	negative selection	5149410
74381031	74381053	4	-	27760321	HT29	viability after 16 days	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.7773197158442107	[614,479]	[1333,830,1016]	8	hSpCas9	negative selection	5149411
74381117	74381139	4	+	27760321	HT29	viability after 16 days	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.3093326957139692	[253,197]	[228,307,394]	3	hSpCas9	negative selection	5149412
74382692	74382714	4	-	27760321	HT29	viability after 16 days	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.293434250820234	[212,165]	[233,257,284]	3	hSpCas9	negative selection	5149413
74379484	74379506	4	+	27760321	HT29	viability after 13 days	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.1377534479789654	[343,268]	[331,303,332]	-2	hSpCas9	negative selection	5232872
74379501	74379523	4	-	27760321	HT29	viability after 13 days	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.1004922657399941	[403,314]	[375,544,421]	1	hSpCas9	negative selection	5232873
74381031	74381053	4	-	27760321	HT29	viability after 13 days	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.44019583577119614	[614,479]	[1097,852,646]	5	hSpCas9	negative selection	5232874
74381117	74381139	4	+	27760321	HT29	viability after 13 days	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.08913854937489518	[253,197]	[240,177,315]	-1	hSpCas9	negative selection	5232875
74382692	74382714	4	-	27760321	HT29	viability after 13 days	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.37739767982769445	[212,165]	[261,212,375]	5	hSpCas9	negative selection	5232876
74379484	74379506	4	+	27760321	HT29	viability after 10 days	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.030022908070721055	[343,268]	[431,346,391]	0	hSpCas9	negative selection	5316335
74379501	74379523	4	-	27760321	HT29	viability after 10 days	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	0.2566593982104984	[403,314]	[582,563,463]	3	hSpCas9	negative selection	5316336
74381031	74381053	4	-	27760321	HT29	viability after 10 days	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.24084234436341934	[614,479]	[561,1113,756]	3	hSpCas9	negative selection	5316337
74381117	74381139	4	+	27760321	HT29	viability after 10 days	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.2727517214077372	[253,197]	[312,265,124]	-3	hSpCas9	negative selection	5316338
74382692	74382714	4	-	27760321	HT29	viability after 10 days	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.11565175115945425	[212,165]	[194,264,307]	1	hSpCas9	negative selection	5316339
74379484	74379506	4	+	27760321	MOLM13	viability	TGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.9201824248553425	[362,343]	[433,329]	6	hSpCas9	negative selection	5399798
74379501	74379523	4	-	27760321	MOLM13	viability	AGTTATCACTGGACTCTCCTGG	EREG	ENSG00000124882	1.3164242674065023	[471,403]	[881,384]	8	hSpCas9	negative selection	5399799
74381031	74381053	4	-	27760321	MOLM13	viability	TTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.2743100373716649	[693,614]	[615,300]	1	hSpCas9	negative selection	5399800
74381117	74381139	4	+	27760321	MOLM13	viability	CATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-1.189925177715033	[276,253]	[130,9]	-6	hSpCas9	negative selection	5399801
74382692	74382714	4	-	27760321	MOLM13	viability	TTGCTTAAAGGTTGGTGGACGG	EREG	ENSG00000124882	0.22726935399563508	[256,212]	[207,108]	1	hSpCas9	negative selection	5399802
74365179	74365202	4	+	27661255	K562	viability	GCCAACGTGGGGTCCCTTCTAGG	EREG	ENSG00000124882	0.06408168907873513	[451,552]	[463,378]	2	dCas9-KRAB	negative selection	5477747
74365129	74365152	4	-	27661255	K562	viability	GGCAAGTGAGCTCAACTGTCTGG	EREG	ENSG00000124882	0.26009306071948257	[398,415]	[368,406]	8	dCas9-KRAB	negative selection	5477748
74365192	74365215	4	-	27661255	K562	viability	GAGCGGCTGTCAGCCTAGAAGGG	EREG	ENSG00000124882	-0.16279899617999172	[479,489]	[393,304]	-5	dCas9-KRAB	negative selection	5477749
74365216	74365239	4	-	27661255	K562	viability	GACGGGCTCGCGGCAGTGGCTGG	EREG	ENSG00000124882	0.10988191706729222	[791,885]	[751,695]	4	dCas9-KRAB	negative selection	5477750
74365226	74365249	4	-	27661255	K562	viability	GGCGGGAGCAGACGGGCTCGCGG	EREG	ENSG00000124882	0.05675207739404772	[796,637]	[665,540]	2	dCas9-KRAB	negative selection	5477751
74365386	74365409	4	-	27661255	K562	viability	GGGGCGGCCGGAAGCCAGAGGGG	EREG	ENSG00000124882	-0.15476214295885948	[556,863]	[534,480]	-5	dCas9-KRAB	negative selection	5477752
74384797	74384820	4	-	27260156	BXPC3	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.03204738859604306	[145]	[176,131,150,131]	0	hSpCas9	negative selection	5541607
74381090	74381113	4	+	27260156	BXPC3	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.06842635699212285	[1289]	[1293,1319,1608,1450]	1	hSpCas9	negative selection	5541608
74382748	74382771	4	+	27260156	BXPC3	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.10907147282445306	[913]	[924,875,1163,1193]	2	hSpCas9	negative selection	5541609
74381031	74381054	4	-	27260156	BXPC3	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.11688215997869278	[692]	[595,708,870,1016]	2	hSpCas9	negative selection	5605872
74379483	74379506	4	+	27260156	BXPC3	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.40268262281769185	[137]	[147,237,156,223]	8	hSpCas9	negative selection	5605873
74379511	74379534	4	-	27260156	BXPC3	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.5592010561838858	[876]	[538,487,784,702]	-8	hSpCas9	negative selection	5605874
74384797	74384820	4	-	27260156	A673	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.056027913871752544	[145]	[183,219,144,178]	1	hSpCas9	negative selection	5662858
74381090	74381113	4	+	27260156	A673	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.11011136809924249	[1289]	[1541,1796,1562,1769]	2	hSpCas9	negative selection	5662859
74382748	74382771	4	+	27260156	A673	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.17579481778800754	[913]	[1437,1058,1287,1195]	4	hSpCas9	negative selection	5662860
74381031	74381054	4	-	27260156	A673	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.22758315955162922	[692]	[1062,864,932,1051]	5	hSpCas9	negative selection	5727123
74379483	74379506	4	+	27260156	A673	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.28850722765951287	[137]	[183,163,249,209]	6	hSpCas9	negative selection	5727124
74379511	74379534	4	-	27260156	A673	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.1878646658765104	[876]	[1026,953,819,905]	-5	hSpCas9	negative selection	5727125
74384797	74384820	4	-	27260156	A375	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.033842861701138816	[145]	[184,205,98,207]	0	hSpCas9	negative selection	5784109
74381090	74381113	4	+	27260156	A375	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.22996946244202587	[1289]	[1865,2094,1917,1286]	3	hSpCas9	negative selection	5784110
74382748	74382771	4	+	27260156	A375	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.5472956790189099	[913]	[1504,1661,1438,1632]	7	hSpCas9	negative selection	5784111
74381031	74381054	4	-	27260156	A375	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.31170009178728986	[692]	[1121,1281,857,814]	4	hSpCas9	negative selection	5848374
74379483	74379506	4	+	27260156	A375	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.5176792243927646	[137]	[151,265,291,217]	7	hSpCas9	negative selection	5848375
74379511	74379534	4	-	27260156	A375	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.0318574654115763	[876]	[936,1144,1074,880]	0	hSpCas9	negative selection	5848376
74384797	74384820	4	-	27260156	COLO741	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.19869478131672325	[145]	[119,257,252]	4	hSpCas9	negative selection	5905360
74381090	74381113	4	+	27260156	COLO741	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.08180257221781329	[1289]	[1768,1482,1442]	-2	hSpCas9	negative selection	5905361
74382748	74382771	4	+	27260156	COLO741	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.16930019638035354	[913]	[1376,1348,1222]	3	hSpCas9	negative selection	5905362
74381031	74381054	4	-	27260156	COLO741	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.07903682547663193	[692]	[992,1038,787]	1	hSpCas9	negative selection	5969625
74379483	74379506	4	+	27260156	COLO741	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.37962399207907294	[137]	[231,227,227]	7	hSpCas9	negative selection	5969626
74379511	74379534	4	-	27260156	COLO741	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.21114163637400152	[876]	[955,1090,861]	-4	hSpCas9	negative selection	5969627
74384797	74384820	4	-	27260156	CAL120	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.6747674087187789	[145]	[167,80,596]	8	hSpCas9	negative selection	6026611
74381090	74381113	4	+	27260156	CAL120	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.3203949696136805	[1289]	[2496,1774,1817]	5	hSpCas9	negative selection	6026612
74382748	74382771	4	+	27260156	CAL120	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.39454436399566983	[913]	[1903,1302,1341]	6	hSpCas9	negative selection	6026613
74381031	74381054	4	-	27260156	CAL120	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.26470302804858414	[692]	[1502,922,756]	4	hSpCas9	negative selection	6090876
74379483	74379506	4	+	27260156	CAL120	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.9387825838796723	[137]	[675,224,141]	9	hSpCas9	negative selection	6090877
74379511	74379534	4	-	27260156	CAL120	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.040097653075101936	[876]	[1076,871,1233]	0	hSpCas9	negative selection	6090878
74384797	74384820	4	-	27260156	CADOES1	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.0637633531869568	[145]	[115,71,150,231]	1	hSpCas9	negative selection	6147862
74381090	74381113	4	+	27260156	CADOES1	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.1582704460751465	[1289]	[1366,1306,1301,1380]	2	hSpCas9	negative selection	6147863
74382748	74382771	4	+	27260156	CADOES1	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.19327075865562593	[913]	[979,863,1006,1038]	3	hSpCas9	negative selection	6147864
74381031	74381054	4	-	27260156	CADOES1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.16070212128838368	[692]	[540,509,736,515]	-3	hSpCas9	negative selection	6212127
74379483	74379506	4	+	27260156	CADOES1	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.36562771847735	[137]	[138,80,86,90]	-6	hSpCas9	negative selection	6212128
74379511	74379534	4	-	27260156	CADOES1	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.18090571911955167	[876]	[653,702,909,606]	-3	hSpCas9	negative selection	6212129
74384797	74384820	4	-	27260156	EWS502	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.4305883227125482	[145]	[92,129,132,103]	-6	hSpCas9	negative selection	6269113
74381090	74381113	4	+	27260156	EWS502	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.2587827443400701	[1289]	[1604,1389,1652,1918]	4	hSpCas9	negative selection	6269114
74382748	74382771	4	+	27260156	EWS502	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.13052983528074025	[913]	[1011,822,1207,1220]	2	hSpCas9	negative selection	6269115
74381031	74381054	4	-	27260156	EWS502	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.06273316202534551	[692]	[597,887,694,626]	-1	hSpCas9	negative selection	6333378
74379483	74379506	4	+	27260156	EWS502	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.28734371199546604	[137]	[111,144,121,97]	-5	hSpCas9	negative selection	6333379
74379511	74379534	4	-	27260156	EWS502	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.4204231709311151	[876]	[439,760,615,1005]	-6	hSpCas9	negative selection	6333380
74384797	74384820	4	-	27260156	EW8	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.17857132122509367	[145]	[218,110,107,110]	3	hSpCas9	negative selection	6390364
74381090	74381113	4	+	27260156	EW8	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.331750453716549	[1289]	[1488,1027,1221,1552]	6	hSpCas9	negative selection	6390365
74382748	74382771	4	+	27260156	EW8	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.1455140381456197	[913]	[957,694,792,847]	2	hSpCas9	negative selection	6390366
74381031	74381054	4	-	27260156	EW8	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.0744970427322299	[692]	[652,507,705,483]	1	hSpCas9	negative selection	6454629
74379483	74379506	4	+	27260156	EW8	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.3067543522420384	[137]	[90,85,86,97]	-5	hSpCas9	negative selection	6454630
74379511	74379534	4	-	27260156	EW8	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.024578648148420257	[876]	[999,600,644,686]	0	hSpCas9	negative selection	6454631
74384797	74384820	4	-	27260156	CORL105	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.09459260251313073	[145]	[139,147,195,246]	1	hSpCas9	negative selection	6511615
74381090	74381113	4	+	27260156	CORL105	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.15122478480910262	[1289]	[1885,1771,1487,1537]	3	hSpCas9	negative selection	6511616
74382748	74382771	4	+	27260156	CORL105	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.24664820367098605	[913]	[1498,1156,1399,1052]	4	hSpCas9	negative selection	6511617
74381031	74381054	4	-	27260156	CORL105	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.002111336521806173	[692]	[641,801,1029,803]	0	hSpCas9	negative selection	6575880
74379483	74379506	4	+	27260156	CORL105	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.20888435580660514	[137]	[192,180,216,160]	4	hSpCas9	negative selection	6575881
74379511	74379534	4	-	27260156	CORL105	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.12792427128305273	[876]	[886,863,1238,814]	-2	hSpCas9	negative selection	6575882
74384797	74384820	4	-	27260156	HS294T	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.0829210943301586	[145]	[36,99,41,60]	1	hSpCas9	negative selection	6632866
74381090	74381113	4	+	27260156	HS294T	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.23774945191877683	[1289]	[630,559,459,717]	3	hSpCas9	negative selection	6632867
74382748	74382771	4	+	27260156	HS294T	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.3849022339792192	[913]	[345,532,397,598]	5	hSpCas9	negative selection	6632868
74381031	74381054	4	-	27260156	HS294T	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.1298753056580348	[692]	[295,183,254,239]	-2	hSpCas9	negative selection	6697131
74379483	74379506	4	+	27260156	HS294T	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.07743133825136961	[137]	[35,67,37,62]	-1	hSpCas9	negative selection	6697132
74379511	74379534	4	-	27260156	HS294T	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.3925844469313474	[876]	[272,191,260,316]	-5	hSpCas9	negative selection	6697133
74384797	74384820	4	-	27260156	HCC44	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-1.1657026133088955	[145]	[88,38,111,66]	-9	hSpCas9	negative selection	6754117
74381090	74381113	4	+	27260156	HCC44	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.11550688465670311	[1289]	[1341,1120,2455,1584]	1	hSpCas9	negative selection	6754118
74382748	74382771	4	+	27260156	HCC44	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.14701933103414833	[913]	[1113,866,1861,894]	2	hSpCas9	negative selection	6754119
74381031	74381054	4	-	27260156	HCC44	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.010933875548107319	[692]	[1106,744,720,608]	0	hSpCas9	negative selection	6818382
74379483	74379506	4	+	27260156	HCC44	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.012898941670775876	[137]	[147,147,179,156]	0	hSpCas9	negative selection	6818383
74379511	74379534	4	-	27260156	HCC44	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.46736254977722236	[876]	[651,806,789,611]	-6	hSpCas9	negative selection	6818384
74384797	74384820	4	-	27260156	G402	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.6082399584272362	[145]	[111,123,140,90]	-6	hSpCas9	negative selection	6875368
74381090	74381113	4	+	27260156	G402	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.6034206218642337	[1289]	[2718,2026,2449,2386]	7	hSpCas9	negative selection	6875369
74382748	74382771	4	+	27260156	G402	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.6456827284749151	[913]	[1812,1685,1546,1923]	7	hSpCas9	negative selection	6875370
74381031	74381054	4	-	27260156	G402	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.0626065952663395	[692]	[515,925,846,1174]	0	hSpCas9	negative selection	6939633
74379483	74379506	4	+	27260156	G402	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.17430851573004258	[137]	[252,120,135,101]	-2	hSpCas9	negative selection	6939634
74379511	74379534	4	-	27260156	G402	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.0040329765202565815	[876]	[985,1383,1003,926]	0	hSpCas9	negative selection	6939635
74384797	74384820	4	-	27260156	L33	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.358850699761291	[145]	[148,88,129,176]	7	hSpCas9	negative selection	6996619
74381090	74381113	4	+	27260156	L33	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.05816528019909262	[1289]	[976,635,724,1278]	-1	hSpCas9	negative selection	6996620
74382748	74382771	4	+	27260156	L33	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.15485887763839057	[913]	[911,424,726,967]	3	hSpCas9	negative selection	6996621
74381031	74381054	4	-	27260156	L33	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.21427149661150946	[692]	[598,221,401,608]	-5	hSpCas9	negative selection	7060884
74379483	74379506	4	+	27260156	L33	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.308039346380395	[137]	[116,43,76,98]	-6	hSpCas9	negative selection	7060885
74379511	74379534	4	-	27260156	L33	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.36320208442649315	[876]	[547,312,487,642]	-7	hSpCas9	negative selection	7060886
74384797	74384820	4	-	27260156	K562	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.8899233034113433	[145]	[246,354,246,129]	9	hSpCas9	negative selection	7117870
74381090	74381113	4	+	27260156	K562	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.20674375414192947	[1289]	[1077,1154,1418,1568]	2	hSpCas9	negative selection	7117871
74382748	74382771	4	+	27260156	K562	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.5007273064005178	[913]	[1722,638,1566,726]	6	hSpCas9	negative selection	7117872
74381031	74381054	4	-	27260156	K562	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.15688728717483535	[692]	[1108,1092,429,218]	2	hSpCas9	negative selection	7182135
74379483	74379506	4	+	27260156	K562	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.3105972093103315	[137]	[100,39,295,158]	4	hSpCas9	negative selection	7182136
74379511	74379534	4	-	27260156	K562	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.08274721009009445	[876]	[690,1463,447,406]	-1	hSpCas9	negative selection	7182137
74384797	74384820	4	-	27260156	HT29	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.1470916053019098	[145]	[202,200,102,141]	-3	hSpCas9	negative selection	7239121
74381090	74381113	4	+	27260156	HT29	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.14450393882628165	[1289]	[1954,2171,1649,1257]	3	hSpCas9	negative selection	7239122
74382748	74382771	4	+	27260156	HT29	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.18283168448602916	[913]	[1412,1286,1272,1096]	3	hSpCas9	negative selection	7239123
74381031	74381054	4	-	27260156	HT29	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.1258365792614402	[692]	[1122,937,1026,634]	2	hSpCas9	negative selection	7303386
74379483	74379506	4	+	27260156	HT29	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.09308296613814715	[137]	[196,225,181,121]	1	hSpCas9	negative selection	7303387
74379511	74379534	4	-	27260156	HT29	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.3719679688379356	[876]	[1068,893,813,568]	-6	hSpCas9	negative selection	7303388
74384797	74384820	4	-	27260156	MHHES1	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.20081764133244961	[145]	[284,175,134,169]	3	hSpCas9	negative selection	7360372
74381090	74381113	4	+	27260156	MHHES1	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.09735776736761048	[1289]	[1554,1381,1740,867]	-2	hSpCas9	negative selection	7360373
74382748	74382771	4	+	27260156	MHHES1	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.32357028432326485	[913]	[1454,1807,941,1045]	6	hSpCas9	negative selection	7360374
74381031	74381054	4	-	27260156	MHHES1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.1495783344431969	[692]	[743,906,608,589]	-3	hSpCas9	negative selection	7424637
74379483	74379506	4	+	27260156	MHHES1	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.05222902468519419	[137]	[250,150,61,144]	-1	hSpCas9	negative selection	7424638
74379511	74379534	4	-	27260156	MHHES1	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.11988317386222991	[876]	[875,825,1083,834]	-2	hSpCas9	negative selection	7424639
74384797	74384820	4	-	27260156	MEWO	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.10635376822716935	[145]	[151,157,131]	2	hSpCas9	negative selection	7481623
74381090	74381113	4	+	27260156	MEWO	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.05079803951350814	[1289]	[1325,1014,1185]	-1	hSpCas9	negative selection	7481624
74382748	74382771	4	+	27260156	MEWO	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	-0.014190375760850027	[913]	[1202,648,757]	0	hSpCas9	negative selection	7481625
74381031	74381054	4	-	27260156	MEWO	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.14773578451687686	[692]	[936,509,750]	3	hSpCas9	negative selection	7545888
74379483	74379506	4	+	27260156	MEWO	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.3968121344340152	[137]	[194,119,199]	8	hSpCas9	negative selection	7545889
74379511	74379534	4	-	27260156	MEWO	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.2772751656607392	[876]	[767,583,696]	-6	hSpCas9	negative selection	7545890
74384797	74384820	4	-	27260156	LNCAPCLONEFGC	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.048286904091038974	[145]	[81,190,133,136]	0	hSpCas9	negative selection	7602874
74381090	74381113	4	+	27260156	LNCAPCLONEFGC	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.12730667595762757	[1289]	[1341,1051,1497,1258]	2	hSpCas9	negative selection	7602875
74382748	74382771	4	+	27260156	LNCAPCLONEFGC	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.47193598931528147	[913]	[859,1153,1317,1290]	7	hSpCas9	negative selection	7602876
74381031	74381054	4	-	27260156	LNCAPCLONEFGC	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.034452293684002155	[692]	[663,561,607,618]	0	hSpCas9	negative selection	7667139
74379483	74379506	4	+	27260156	LNCAPCLONEFGC	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.2473972289140174	[137]	[164,97,252,95]	4	hSpCas9	negative selection	7667140
74379511	74379534	4	-	27260156	LNCAPCLONEFGC	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.17446666644793396	[876]	[451,788,908,694]	-3	hSpCas9	negative selection	7667141
74384797	74384820	4	-	27260156	PANC0327	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.9211379993225782	[145]	[332,188,346,127]	9	hSpCas9	negative selection	7724125
74381090	74381113	4	+	27260156	PANC0327	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.34547905164821624	[1289]	[1184,1294,1150,2189]	5	hSpCas9	negative selection	7724126
74382748	74382771	4	+	27260156	PANC0327	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.638524573943807	[913]	[1531,1636,999,859]	8	hSpCas9	negative selection	7724127
74381031	74381054	4	-	27260156	PANC0327	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.037330983793135375	[692]	[533,623,772,588]	0	hSpCas9	negative selection	7788390
74379483	74379506	4	+	27260156	PANC0327	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.3898942043119651	[137]	[167,110,47,50]	-5	hSpCas9	negative selection	7788391
74379511	74379534	4	-	27260156	PANC0327	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.4588364791307828	[876]	[653,398,642,599]	-6	hSpCas9	negative selection	7788392
74384797	74384820	4	-	27260156	NCIH2009	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.010300780955157407	[145]	[76,226,277]	0	hSpCas9	negative selection	7845376
74381090	74381113	4	+	27260156	NCIH2009	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.02159892907250094	[1289]	[1995,1793,1728]	0	hSpCas9	negative selection	7845377
74382748	74382771	4	+	27260156	NCIH2009	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.4707822205748289	[913]	[1877,1528,1924]	6	hSpCas9	negative selection	7845378
74381031	74381054	4	-	27260156	NCIH2009	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.1359345247890213	[692]	[1063,888,724]	-2	hSpCas9	negative selection	7909641
74379483	74379506	4	+	27260156	NCIH2009	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.4081470969294345	[137]	[217,235,305]	5	hSpCas9	negative selection	7909642
74379511	74379534	4	-	27260156	NCIH2009	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.07995285689681142	[876]	[1131,1291,1426]	1	hSpCas9	negative selection	7909643
74384797	74384820	4	-	27260156	NCIH1373	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.748481533270865	[145]	[61,69,129,32]	-6	hSpCas9	negative selection	7966627
74381090	74381113	4	+	27260156	NCIH1373	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.4244001163304627	[1289]	[1896,1987,1934,503]	4	hSpCas9	negative selection	7966628
74382748	74382771	4	+	27260156	NCIH1373	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.8810524486531202	[913]	[2922,1424,1699,444]	8	hSpCas9	negative selection	7966629
74381031	74381054	4	-	27260156	NCIH1373	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.10094978080675676	[692]	[755,931,766,223]	1	hSpCas9	negative selection	8030892
74379483	74379506	4	+	27260156	NCIH1373	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.1442133118887179	[137]	[315,98,40,35]	-1	hSpCas9	negative selection	8030893
74379511	74379534	4	-	27260156	NCIH1373	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.6037491000991764	[876]	[529,724,703,155]	-5	hSpCas9	negative selection	8030894
74384797	74384820	4	-	27260156	PATU8902	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.7993057127303641	[145]	[397,391,289,347]	8	hSpCas9	negative selection	8087878
74381090	74381113	4	+	27260156	PATU8902	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.7116270701537295	[1289]	[3285,1916,2569,4212]	7	hSpCas9	negative selection	8087879
74382748	74382771	4	+	27260156	PATU8902	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.7770392611427768	[913]	[2303,2478,1156,3148]	7	hSpCas9	negative selection	8087880
74381031	74381054	4	-	27260156	PATU8902	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.47215432447208816	[692]	[1832,1001,1201,1334]	5	hSpCas9	negative selection	8152143
74379483	74379506	4	+	27260156	PATU8902	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.729015303706916	[137]	[414,369,176,348]	7	hSpCas9	negative selection	8152144
74379511	74379534	4	-	27260156	PATU8902	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.12193484369774121	[876]	[934,1187,850,1641]	-1	hSpCas9	negative selection	8152145
74384797	74384820	4	-	27260156	PANC1	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.22299017945560307	[145]	[105,71,201,50]	-4	hSpCas9	negative selection	8209129
74381090	74381113	4	+	27260156	PANC1	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.19443048136268848	[1289]	[1178,1858,1167,1009]	3	hSpCas9	negative selection	8209130
74382748	74382771	4	+	27260156	PANC1	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.4217396483201916	[913]	[1073,1102,1094,944]	6	hSpCas9	negative selection	8209131
74381031	74381054	4	-	27260156	PANC1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.1884543305768691	[692]	[551,1048,564,622]	3	hSpCas9	negative selection	8273394
74379483	74379506	4	+	27260156	PANC1	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.05204781026525218	[137]	[128,85,170,99]	0	hSpCas9	negative selection	8273395
74379511	74379534	4	-	27260156	PANC1	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.21682566856041274	[876]	[582,738,785,516]	-4	hSpCas9	negative selection	8273396
74384797	74384820	4	-	27260156	PANC0813	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.3614642364317051	[145]	[126,245,354,148]	6	hSpCas9	negative selection	8330380
74381090	74381113	4	+	27260156	PANC0813	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.11082765786215987	[1289]	[1817,1580,1425,1727]	1	hSpCas9	negative selection	8330381
74382748	74382771	4	+	27260156	PANC0813	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.22881050068300568	[913]	[1408,970,1555,1117]	3	hSpCas9	negative selection	8330382
74381031	74381054	4	-	27260156	PANC0813	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.22806255089769945	[692]	[1068,1331,615,811]	3	hSpCas9	negative selection	8394645
74379483	74379506	4	+	27260156	PANC0813	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.5135190426966811	[137]	[131,133,367,279]	7	hSpCas9	negative selection	8394646
74379511	74379534	4	-	27260156	PANC0813	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.11686818564483581	[876]	[1222,1148,1301,819]	2	hSpCas9	negative selection	8394647
74384797	74384820	4	-	27260156	RDES	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.7554793282349113	[145]	[90,104,120,75]	-8	hSpCas9	negative selection	8451631
74381090	74381113	4	+	27260156	RDES	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.23996557596094537	[1289]	[1411,1687,1907,2082]	4	hSpCas9	negative selection	8451632
74382748	74382771	4	+	27260156	RDES	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.3455010874443305	[913]	[1066,1338,1497,1483]	5	hSpCas9	negative selection	8451633
74381031	74381054	4	-	27260156	RDES	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.09705162035981652	[692]	[853,651,1133,755]	1	hSpCas9	negative selection	8515896
74379483	74379506	4	+	27260156	RDES	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.301123789872872	[137]	[130,121,142,112]	-5	hSpCas9	negative selection	8515897
74379511	74379534	4	-	27260156	RDES	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.15514897125292393	[876]	[773,857,1014,998]	-3	hSpCas9	negative selection	8515898
74384797	74384820	4	-	27260156	PC3	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.00364659391989286	[145]	[174,82,267,63]	0	hSpCas9	negative selection	8572882
74381090	74381113	4	+	27260156	PC3	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.07781687691748851	[1289]	[716,1024,2337,1355]	-2	hSpCas9	negative selection	8572883
74382748	74382771	4	+	27260156	PC3	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.33399241702304616	[913]	[948,1146,1198,1264]	7	hSpCas9	negative selection	8572884
74381031	74381054	4	-	27260156	PC3	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.11435325299203236	[692]	[629,480,924,542]	-3	hSpCas9	negative selection	8637147
74379483	74379506	4	+	27260156	PC3	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.03720892729496361	[137]	[110,63,229,197]	0	hSpCas9	negative selection	8637148
74379511	74379534	4	-	27260156	PC3	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	0.01697668778921524	[876]	[589,886,1380,911]	0	hSpCas9	negative selection	8637149
74384797	74384820	4	-	27260156	PATU8988T	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.16205234642563604	[145]	[155,172,174,125]	2	hSpCas9	negative selection	8694133
74381090	74381113	4	+	27260156	PATU8988T	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.22777644673107056	[1289]	[1043,1576,1630,1606]	4	hSpCas9	negative selection	8694134
74382748	74382771	4	+	27260156	PATU8988T	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	-0.006217973997427073	[913]	[791,802,995,920]	0	hSpCas9	negative selection	8694135
74381031	74381054	4	-	27260156	PATU8988T	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.33403434507325236	[692]	[1018,699,520,1151]	6	hSpCas9	negative selection	8758398
74379483	74379506	4	+	27260156	PATU8988T	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.30724596611720645	[137]	[59,384,128,101]	5	hSpCas9	negative selection	8758399
74379511	74379534	4	-	27260156	PATU8988T	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.09912811644718578	[876]	[724,761,916,752]	-2	hSpCas9	negative selection	8758400
74384797	74384820	4	-	27260156	T47D	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.2762634373490849	[145]	[166,229,165,260]	6	hSpCas9	negative selection	8815384
74381090	74381113	4	+	27260156	T47D	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.057983336761549875	[1289]	[1631,1337,1710,1594]	1	hSpCas9	negative selection	8815385
74382748	74382771	4	+	27260156	T47D	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.12473281763827515	[913]	[1178,1026,1208,1241]	2	hSpCas9	negative selection	8815386
74381031	74381054	4	-	27260156	T47D	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.0007373999718128799	[692]	[820,686,851,882]	0	hSpCas9	negative selection	8879649
74379483	74379506	4	+	27260156	T47D	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.006318647203430228	[137]	[114,184,166,176]	0	hSpCas9	negative selection	8879650
74379511	74379534	4	-	27260156	T47D	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.13690220362064742	[876]	[846,874,938,1063]	-3	hSpCas9	negative selection	8879651
74384797	74384820	4	-	27260156	SU8686	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.23495659619543896	[145]	[143,112,273,160]	4	hSpCas9	negative selection	8936635
74381090	74381113	4	+	27260156	SU8686	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.16129532078518682	[1289]	[1217,1186,1631,1793]	2	hSpCas9	negative selection	8936636
74382748	74382771	4	+	27260156	SU8686	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.47138682175636726	[913]	[1040,1087,1481,1496]	7	hSpCas9	negative selection	8936637
74381031	74381054	4	-	27260156	SU8686	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.22343316981837302	[692]	[813,748,758,900]	4	hSpCas9	negative selection	9000900
74379483	74379506	4	+	27260156	SU8686	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.10829781025356566	[137]	[90,145,164,202]	1	hSpCas9	negative selection	9000901
74379511	74379534	4	-	27260156	SU8686	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.10118092232601761	[876]	[544,726,979,1072]	-2	hSpCas9	negative selection	9000902
74384797	74384820	4	-	27260156	SKES1	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.09353442787862853	[145]	[159,115,128,139]	-2	hSpCas9	negative selection	9057886
74381090	74381113	4	+	27260156	SKES1	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.07321487639675328	[1289]	[1470,1282,1167,1023]	-1	hSpCas9	negative selection	9057887
74382748	74382771	4	+	27260156	SKES1	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.14391105699038564	[913]	[1078,843,1294,810]	3	hSpCas9	negative selection	9057888
74381031	74381054	4	-	27260156	SKES1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.2063816108445683	[692]	[846,696,936,704]	4	hSpCas9	negative selection	9122151
74379483	74379506	4	+	27260156	SKES1	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.007297491686499846	[137]	[259,125,118,65]	0	hSpCas9	negative selection	9122152
74379511	74379534	4	-	27260156	SKES1	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.3099185947901453	[876]	[708,936,676,540]	-6	hSpCas9	negative selection	9122153
74384797	74384820	4	-	27260156	TOV112D	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	-0.42516045351866993	[145]	[119,123,47,146]	-7	hSpCas9	negative selection	9179137
74381090	74381113	4	+	27260156	TOV112D	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.03512140167796152	[1289]	[1052,1607,1598,1086]	0	hSpCas9	negative selection	9179138
74382748	74382771	4	+	27260156	TOV112D	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.17009828676709304	[913]	[821,1487,859,1042]	3	hSpCas9	negative selection	9179139
74381031	74381054	4	-	27260156	TOV112D	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.09272582984176636	[692]	[786,1081,675,508]	1	hSpCas9	negative selection	9243402
74379483	74379506	4	+	27260156	TOV112D	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.005208791379491595	[137]	[140,141,59,206]	0	hSpCas9	negative selection	9243403
74379511	74379534	4	-	27260156	TOV112D	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.4197367385167936	[876]	[556,608,698,737]	-7	hSpCas9	negative selection	9243404
74384797	74384820	4	-	27260156	TC71	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.3601067644801035	[145]	[153,202,235,210]	8	hSpCas9	negative selection	9300388
74381090	74381113	4	+	27260156	TC71	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	-0.024963989256298724	[1289]	[1229,1292,1488,1426]	0	hSpCas9	negative selection	9300389
74382748	74382771	4	+	27260156	TC71	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.14035185070253053	[913]	[1247,1057,937,1075]	3	hSpCas9	negative selection	9300390
74381031	74381054	4	-	27260156	TC71	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.032907765749521034	[692]	[779,675,795,787]	0	hSpCas9	negative selection	9364653
74379483	74379506	4	+	27260156	TC71	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	0.2537641571577982	[137]	[158,195,163,187]	6	hSpCas9	negative selection	9364654
74379511	74379534	4	-	27260156	TC71	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.3333107068379072	[876]	[856,644,778,696]	-7	hSpCas9	negative selection	9364655
74384797	74384820	4	-	27260156	TC32	viability	GATGGCGCCATTCAGACTTGCGG	EREG	ENSG00000124882	0.4199628484254776	[145]	[181,155,239,163]	7	hSpCas9	negative selection	9421639
74381090	74381113	4	+	27260156	TC32	viability	GCATGGACAGTGCATCTATCTGG	EREG	ENSG00000124882	0.16997846199376299	[1289]	[1222,1070,1790,1498]	3	hSpCas9	negative selection	9421640
74382748	74382771	4	+	27260156	TC32	viability	TTGTTTCTTATCACAGTCGTCGG	EREG	ENSG00000124882	0.38250410259630474	[913]	[1193,851,1214,1264]	6	hSpCas9	negative selection	9421641
74381031	74381054	4	-	27260156	TC32	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.16918605215374016	[692]	[650,553,1100,720]	3	hSpCas9	negative selection	9485904
74379483	74379506	4	+	27260156	TC32	viability	GTGATTCCATCATGTATCCCAGG	EREG	ENSG00000124882	-0.25093415906421157	[137]	[133,63,149,101]	-4	hSpCas9	negative selection	9485905
74379511	74379534	4	-	27260156	TC32	viability	TAAAGCTGTGCAGTTATCACTGG	EREG	ENSG00000124882	-0.46900070680537875	[876]	[512,299,909,816]	-7	hSpCas9	negative selection	9485906
74365297	74365320	4	+	27869803	HPAFII	viability after 27 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.021769878540000454	[348]	[32,313,NaN]	0	hSpCas9	negative selection	9588850
74365328	74365351	4	+	27869803	HPAFII	viability after 27 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.7944421231871704	[197]	[287,90,NaN]	6	hSpCas9	negative selection	9588851
74365329	74365352	4	+	27869803	HPAFII	viability after 27 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.6350075341329351	[156]	[227,44,NaN]	5	hSpCas9	negative selection	9588852
74379452	74379475	4	-	27869803	HPAFII	viability after 27 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.9000212743768764	[417]	[366,445,NaN]	7	hSpCas9	negative selection	9588853
74381031	74381054	4	-	27869803	HPAFII	viability after 27 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.4110187284524913	[263]	[195,174,NaN]	3	hSpCas9	negative selection	9588854
74365297	74365320	4	+	27869803	HPAFII	viability after 15 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	-0.3223152894295762	[348]	[307,294,NaN]	-4	hSpCas9	negative selection	9671299
74365328	74365351	4	+	27869803	HPAFII	viability after 15 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.5050485147608124	[197]	[420,227,NaN]	6	hSpCas9	negative selection	9671300
74365329	74365352	4	+	27869803	HPAFII	viability after 15 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.0233252945770126	[156]	[268,101,NaN]	0	hSpCas9	negative selection	9671301
74379452	74379475	4	-	27869803	HPAFII	viability after 15 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.6554006262350757	[417]	[767,669,NaN]	7	hSpCas9	negative selection	9671302
74381031	74381054	4	-	27869803	HPAFII	viability after 15 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.4678556995132184	[263]	[339,424,NaN]	5	hSpCas9	negative selection	9671303
74365297	74365320	4	+	27869803	ASPC1	viability after 36 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.061917004828324296	[907]	[368,410,236]	0	hSpCas9	negative selection	9753748
74365328	74365351	4	+	27869803	ASPC1	viability after 36 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.9171653512214322	[418]	[353,67,383]	8	hSpCas9	negative selection	9753749
74365329	74365352	4	+	27869803	ASPC1	viability after 36 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.8810247527781871	[448]	[191,68,21]	-7	hSpCas9	negative selection	9753750
74379452	74379475	4	-	27869803	ASPC1	viability after 36 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-0.16500171655386064	[895]	[295,268,271]	-2	hSpCas9	negative selection	9753751
74381031	74381054	4	-	27869803	ASPC1	viability after 36 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3216306613580606	[683]	[806,75,114]	3	hSpCas9	negative selection	9753752
74365297	74365320	4	+	27869803	PATU8988S	viability after 35 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.7666226267933782	[761]	[572,470,NaN]	7	hSpCas9	negative selection	9836197
74365328	74365351	4	+	27869803	PATU8988S	viability after 35 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-0.3082085973889098	[305]	[114,83,NaN]	-3	hSpCas9	negative selection	9836198
74365329	74365352	4	+	27869803	PATU8988S	viability after 35 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.0181858123748455	[296]	[84,32,NaN]	-7	hSpCas9	negative selection	9836199
74379452	74379475	4	-	27869803	PATU8988S	viability after 35 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	-0.2431219084452097	[872]	[328,264,NaN]	-3	hSpCas9	negative selection	9836200
74381031	74381054	4	-	27869803	PATU8988S	viability after 35 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	1.0465877631771618	[508]	[622,222,NaN]	9	hSpCas9	negative selection	9836201
74365297	74365320	4	+	27869803	PATU8988S	viability after 31 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.4917930555249947	[761]	[333,545,NaN]	6	hSpCas9	negative selection	9918646
74365328	74365351	4	+	27869803	PATU8988S	viability after 31 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	-0.13812666876441992	[305]	[87,139,NaN]	-1	hSpCas9	negative selection	9918647
74365329	74365352	4	+	27869803	PATU8988S	viability after 31 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.13101373631329694	[296]	[152,99,NaN]	1	hSpCas9	negative selection	9918648
74379452	74379475	4	-	27869803	PATU8988S	viability after 31 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.014917376024622064	[872]	[356,344,NaN]	0	hSpCas9	negative selection	9918649
74381031	74381054	4	-	27869803	PATU8988S	viability after 31 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.922359325089561	[508]	[447,303,NaN]	9	hSpCas9	negative selection	9918650
74365297	74365320	4	+	27869803	HPAFII	viability after 35 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.4217260719171616	[348]	[40,456,NaN]	2	hSpCas9	negative selection	10001095
74365328	74365351	4	+	27869803	HPAFII	viability after 35 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.8322725824293646	[197]	[296,44,NaN]	5	hSpCas9	negative selection	10001096
74365329	74365352	4	+	27869803	HPAFII	viability after 35 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.5720425603108721	[156]	[199,25,NaN]	4	hSpCas9	negative selection	10001097
74379452	74379475	4	-	27869803	HPAFII	viability after 35 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.8948840338090737	[417]	[297,500,NaN]	6	hSpCas9	negative selection	10001098
74381031	74381054	4	-	27869803	HPAFII	viability after 35 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.17817469488779575	[263]	[114,191,NaN]	1	hSpCas9	negative selection	10001099
74365297	74365320	4	+	27869803	HPAFII	viability after 31 days	CTCCCATCGCCGATGACCGCGGG	EREG	ENSG00000124882	0.2102920243987586	[348]	[38,430,NaN]	1	hSpCas9	negative selection	10083544
74365328	74365351	4	+	27869803	HPAFII	viability after 31 days	TGGAGATGCTCTGTGCCGGCAGG	EREG	ENSG00000124882	0.8138792726371349	[197]	[269,113,NaN]	6	hSpCas9	negative selection	10083545
74365329	74365352	4	+	27869803	HPAFII	viability after 31 days	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.5643646358455257	[156]	[214,37,NaN]	4	hSpCas9	negative selection	10083546
74379452	74379475	4	-	27869803	HPAFII	viability after 31 days	TGAGGACTGCCTGTAGAAGATGG	EREG	ENSG00000124882	0.9938203014527093	[417]	[336,608,NaN]	7	hSpCas9	negative selection	10083547
74381031	74381054	4	-	27869803	HPAFII	viability after 31 days	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.21763968799936168	[263]	[91,165,NaN]	-1	hSpCas9	negative selection	10083548
74365313	74365336	4	-	28162770	P31FUJ	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.6447992493731712	[631]	[474]	-5	hSpCas9	negative selection	10151062
74379470	74379493	4	-	28162770	P31FUJ	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.9006287829942498	[257]	[565]	9	hSpCas9	negative selection	10151063
74381031	74381054	4	-	28162770	P31FUJ	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3400265406709223	[397]	[591]	4	hSpCas9	negative selection	10151064
74381116	74381139	4	+	28162770	P31FUJ	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.9526942852216433	[55]	[33]	-6	hSpCas9	negative selection	10151065
74365296	74365319	4	+	28162770	P31FUJ	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.7086456132305083	[87]	[168]	7	hSpCas9	negative selection	10151066
74365329	74365352	4	+	28162770	P31FUJ	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.5903200335015422	[64]	[114]	6	hSpCas9	negative selection	10151067
74365354	74365377	4	-	28162770	P31FUJ	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	0.15211530648812976	[120]	[157]	1	hSpCas9	negative selection	10151068
74379489	74379512	4	-	28162770	P31FUJ	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.46606475107134604	[352]	[572]	5	hSpCas9	negative selection	10151069
74381093	74381116	4	+	28162770	P31FUJ	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.045220027010050234	[784]	[893]	0	hSpCas9	negative selection	10151070
74381018	74381041	4	+	28162770	P31FUJ	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.41142018026044536	[540]	[477]	-4	hSpCas9	negative selection	10151071
74365313	74365336	4	-	28162770	TF1	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	NaN	[NaN]	[414]	1	hSpCas9	negative selection	10320428
74379470	74379493	4	-	28162770	TF1	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10320429
74381031	74381054	4	-	28162770	TF1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	NaN	[NaN]	[444]	1	hSpCas9	negative selection	10320430
74381116	74381139	4	+	28162770	TF1	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10320431
74365296	74365319	4	+	28162770	TF1	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10320432
74365329	74365352	4	+	28162770	TF1	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10320433
74365354	74365377	4	-	28162770	TF1	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10320434
74379489	74379512	4	-	28162770	TF1	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	NaN	[NaN]	[214]	1	hSpCas9	negative selection	10320435
74381093	74381116	4	+	28162770	TF1	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	NaN	[NaN]	[538]	1	hSpCas9	negative selection	10320436
74381018	74381041	4	+	28162770	TF1	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	NaN	[NaN]	[429]	1	hSpCas9	negative selection	10320437
74365313	74365336	4	-	28162770	SKM1	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.10057695475157735	[167]	[276]	-1	hSpCas9	negative selection	10489794
74379470	74379493	4	-	28162770	SKM1	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	-0.1187192301120879	[77]	[126]	-1	hSpCas9	negative selection	10489795
74381031	74381054	4	-	28162770	SKM1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.42479206680457726	[133]	[317]	4	hSpCas9	negative selection	10489796
74381116	74381139	4	+	28162770	SKM1	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	1.5839906616538313	[9]	[52]	9	hSpCas9	negative selection	10489797
74365296	74365319	4	+	28162770	SKM1	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.014646775964401448	[35]	[62]	0	hSpCas9	negative selection	10489798
74365329	74365352	4	+	28162770	SKM1	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.1074039168842535	[38]	[31]	-7	hSpCas9	negative selection	10489799
74365354	74365377	4	-	28162770	SKM1	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-0.25263605235186803	[30]	[45]	-2	hSpCas9	negative selection	10489800
74379489	74379512	4	-	28162770	SKM1	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.7118219537073498	[66]	[193]	6	hSpCas9	negative selection	10489801
74381093	74381116	4	+	28162770	SKM1	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.36788667676047115	[172]	[236]	-3	hSpCas9	negative selection	10489802
74381018	74381041	4	+	28162770	SKM1	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.16713718407069322	[140]	[221]	-1	hSpCas9	negative selection	10489803
74365313	74365336	4	-	28162770	SKM1	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.10057695475157735	[167]	[276]	-1	hSpCas9	negative selection	10659160
74379470	74379493	4	-	28162770	SKM1	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	-0.1187192301120879	[77]	[126]	-1	hSpCas9	negative selection	10659161
74381031	74381054	4	-	28162770	SKM1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.42479206680457726	[133]	[317]	4	hSpCas9	negative selection	10659162
74381116	74381139	4	+	28162770	SKM1	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	1.5839906616538313	[9]	[52]	9	hSpCas9	negative selection	10659163
74365296	74365319	4	+	28162770	SKM1	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.014646775964401448	[35]	[62]	0	hSpCas9	negative selection	10659164
74365329	74365352	4	+	28162770	SKM1	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.1074039168842535	[38]	[31]	-7	hSpCas9	negative selection	10659165
74365354	74365377	4	-	28162770	SKM1	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-0.25263605235186803	[30]	[45]	-2	hSpCas9	negative selection	10659166
74379489	74379512	4	-	28162770	SKM1	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.7118219537073498	[66]	[193]	6	hSpCas9	negative selection	10659167
74381093	74381116	4	+	28162770	SKM1	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.36788667676047115	[172]	[236]	-3	hSpCas9	negative selection	10659168
74381018	74381041	4	+	28162770	SKM1	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.16713718407069322	[140]	[221]	-1	hSpCas9	negative selection	10659169
74365313	74365336	4	-	28162770	PL21	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	0.2716306568602902	[747]	[392]	2	hSpCas9	negative selection	10828526
74379470	74379493	4	-	28162770	PL21	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	1.4177310495619468	[171]	[199]	9	hSpCas9	negative selection	10828527
74381031	74381054	4	-	28162770	PL21	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	-0.270798429531109	[534]	[192]	-2	hSpCas9	negative selection	10828528
74381116	74381139	4	+	28162770	PL21	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.35240140853945867	[87]	[29]	-3	hSpCas9	negative selection	10828529
74365296	74365319	4	+	28162770	PL21	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.43043723391111416	[103]	[60]	4	hSpCas9	negative selection	10828530
74365329	74365352	4	+	28162770	PL21	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.93974992991109	[108]	[90]	7	hSpCas9	negative selection	10828531
74365354	74365377	4	-	28162770	PL21	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-1.1534973401253805	[91]	[17]	-6	hSpCas9	negative selection	10828532
74379489	74379512	4	-	28162770	PL21	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.20013961448932005	[281]	[140]	1	hSpCas9	negative selection	10828533
74381093	74381116	4	+	28162770	PL21	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	0.08753180142094363	[585]	[270]	0	hSpCas9	negative selection	10828534
74381018	74381041	4	+	28162770	PL21	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	0.6890895082232591	[408]	[286]	6	hSpCas9	negative selection	10828535
74365313	74365336	4	-	28162770	P31FUJ	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.6447992493731712	[631]	[474]	-5	hSpCas9	negative selection	10997892
74379470	74379493	4	-	28162770	P31FUJ	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.9006287829942498	[257]	[565]	9	hSpCas9	negative selection	10997893
74381031	74381054	4	-	28162770	P31FUJ	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3400265406709223	[397]	[591]	4	hSpCas9	negative selection	10997894
74381116	74381139	4	+	28162770	P31FUJ	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.9526942852216433	[55]	[33]	-6	hSpCas9	negative selection	10997895
74365296	74365319	4	+	28162770	P31FUJ	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.7086456132305083	[87]	[168]	7	hSpCas9	negative selection	10997896
74365329	74365352	4	+	28162770	P31FUJ	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.5903200335015422	[64]	[114]	6	hSpCas9	negative selection	10997897
74365354	74365377	4	-	28162770	P31FUJ	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	0.15211530648812976	[120]	[157]	1	hSpCas9	negative selection	10997898
74379489	74379512	4	-	28162770	P31FUJ	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.46606475107134604	[352]	[572]	5	hSpCas9	negative selection	10997899
74381093	74381116	4	+	28162770	P31FUJ	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.045220027010050234	[784]	[893]	0	hSpCas9	negative selection	10997900
74381018	74381041	4	+	28162770	P31FUJ	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.41142018026044536	[540]	[477]	-4	hSpCas9	negative selection	10997901
74365313	74365336	4	-	28162770	OCIAML5	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.9989079591932681	[371]	[335]	-6	hSpCas9	negative selection	11167258
74379470	74379493	4	-	28162770	OCIAML5	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.35838623716092566	[155]	[360]	3	hSpCas9	negative selection	11167259
74381031	74381054	4	-	28162770	OCIAML5	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.8538863189853939	[220]	[720]	7	hSpCas9	negative selection	11167260
74381116	74381139	4	+	28162770	OCIAML5	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.13479677803871049	[58]	[96]	-1	hSpCas9	negative selection	11167261
74365296	74365319	4	+	28162770	OCIAML5	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.6656534466331157	[28]	[32]	-4	hSpCas9	negative selection	11167262
74365329	74365352	4	+	28162770	OCIAML5	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.8995457992666105	[48]	[164]	7	hSpCas9	negative selection	11167263
74365354	74365377	4	-	28162770	OCIAML5	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-0.13837075602063786	[74]	[122]	-1	hSpCas9	negative selection	11167264
74379489	74379512	4	-	28162770	OCIAML5	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-0.03915212346449226	[221]	[389]	0	hSpCas9	negative selection	11167265
74381093	74381116	4	+	28162770	OCIAML5	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.14870238006392889	[416]	[678]	-1	hSpCas9	negative selection	11167266
74381018	74381041	4	+	28162770	OCIAML5	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	0.36902495314274675	[316]	[738]	3	hSpCas9	negative selection	11167267
74365313	74365336	4	-	28162770	EOL1	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.07201860116593295	[1258]	[630]	0	hSpCas9	negative selection	11336624
74379470	74379493	4	-	28162770	EOL1	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.5578907346625832	[302]	[234]	5	hSpCas9	negative selection	11336625
74381031	74381054	4	-	28162770	EOL1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.32350343476058474	[856]	[564]	3	hSpCas9	negative selection	11336626
74381116	74381139	4	+	28162770	EOL1	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.02122379098220817	[100]	[53]	0	hSpCas9	negative selection	11336627
74365296	74365319	4	+	28162770	EOL1	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	1.2191177508374351	[180]	[221]	8	hSpCas9	negative selection	11336628
74365329	74365352	4	+	28162770	EOL1	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.2474049112187603	[177]	[78]	-2	hSpCas9	negative selection	11336629
74365354	74365377	4	-	28162770	EOL1	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-1.203207775627838	[117]	[26]	-7	hSpCas9	negative selection	11336630
74379489	74379512	4	-	28162770	EOL1	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-0.6604147291506217	[341]	[113]	-5	hSpCas9	negative selection	11336631
74381093	74381116	4	+	28162770	EOL1	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.3262603319299999	[751]	[315]	-2	hSpCas9	negative selection	11336632
74381018	74381041	4	+	28162770	EOL1	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.2609611250902327	[604]	[265]	-2	hSpCas9	negative selection	11336633
74365313	74365336	4	-	28162770	MOLM13	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	0.04061361277205511	[1025]	[762]	0	hSpCas9	negative selection	11505990
74379470	74379493	4	-	28162770	MOLM13	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	-0.1508614326328609	[323]	[210]	-1	hSpCas9	negative selection	11505991
74381031	74381054	4	-	28162770	MOLM13	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.8920675346798914	[707]	[949]	6	hSpCas9	negative selection	11505992
74381116	74381139	4	+	28162770	MOLM13	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	1.9969986475322175	[78]	[227]	9	hSpCas9	negative selection	11505993
74365296	74365319	4	+	28162770	MOLM13	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.7068965167319232	[110]	[130]	5	hSpCas9	negative selection	11505994
74365329	74365352	4	+	28162770	MOLM13	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.12246637794679605	[133]	[88]	0	hSpCas9	negative selection	11505995
74365354	74365377	4	-	28162770	MOLM13	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	0.8281839162289908	[140]	[180]	6	hSpCas9	negative selection	11505996
74379489	74379512	4	-	28162770	MOLM13	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-0.16988981762002542	[458]	[294]	-1	hSpCas9	negative selection	11505997
74381093	74381116	4	+	28162770	MOLM13	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.5101402186198156	[781]	[396]	-3	hSpCas9	negative selection	11505998
74381018	74381041	4	+	28162770	MOLM13	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	0.5416458314976487	[590]	[621]	4	hSpCas9	negative selection	11505999
74365313	74365336	4	-	28162770	HEL	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.633561179754639	[1026]	[423]	-4	hSpCas9	negative selection	11675356
74379470	74379493	4	-	28162770	HEL	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.8191653993846246	[245]	[277]	7	hSpCas9	negative selection	11675357
74381031	74381054	4	-	28162770	HEL	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.3027283781295369	[561]	[443]	2	hSpCas9	negative selection	11675358
74381116	74381139	4	+	28162770	HEL	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	1.375258521135371	[64]	[107]	9	hSpCas9	negative selection	11675359
74365296	74365319	4	+	28162770	HEL	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.5292807822170731	[118]	[109]	4	hSpCas9	negative selection	11675360
74365329	74365352	4	+	28162770	HEL	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	1.0577763312792008	[134]	[179]	8	hSpCas9	negative selection	11675361
74365354	74365377	4	-	28162770	HEL	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-2.928803152958478	[106]	[8]	-8	hSpCas9	negative selection	11675362
74379489	74379512	4	-	28162770	HEL	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-0.24763667682514479	[455]	[245]	-2	hSpCas9	negative selection	11675363
74381093	74381116	4	+	28162770	HEL	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.32811482234012646	[685]	[349]	-2	hSpCas9	negative selection	11675364
74381018	74381041	4	+	28162770	HEL	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.30133575340165075	[505]	[262]	-2	hSpCas9	negative selection	11675365
74365313	74365336	4	-	28162770	MV411	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.2140743782955692	[693]	[503]	-2	hSpCas9	negative selection	11844722
74379470	74379493	4	-	28162770	MV411	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.34384203473583785	[245]	[262]	3	hSpCas9	negative selection	11844723
74381031	74381054	4	-	28162770	MV411	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.4260555266288417	[477]	[540]	4	hSpCas9	negative selection	11844724
74381116	74381139	4	+	28162770	MV411	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.12340014458553328	[74]	[57]	-1	hSpCas9	negative selection	11844725
74365296	74365319	4	+	28162770	MV411	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.38840611894056476	[100]	[64]	-3	hSpCas9	negative selection	11844726
74365329	74365352	4	+	28162770	MV411	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	0.5693656456701377	[91]	[114]	5	hSpCas9	negative selection	11844727
74365354	74365377	4	-	28162770	MV411	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	1.4490714119524255	[39]	[91]	9	hSpCas9	negative selection	11844728
74379489	74379512	4	-	28162770	MV411	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.9114423437598629	[218]	[346]	7	hSpCas9	negative selection	11844729
74381093	74381116	4	+	28162770	MV411	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	-0.4649500206627649	[484]	[295]	-3	hSpCas9	negative selection	11844730
74381018	74381041	4	+	28162770	MV411	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	0.8097010032447969	[362]	[535]	7	hSpCas9	negative selection	11844731
74365313	74365336	4	-	28162770	MONOMAC1	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	0.07802464278983434	[437]	[529]	0	hSpCas9	negative selection	12014088
74379470	74379493	4	-	28162770	MONOMAC1	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	-0.2844996883098932	[152]	[143]	-3	hSpCas9	negative selection	12014089
74381031	74381054	4	-	28162770	MONOMAC1	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.9502212442161149	[334]	[741]	8	hSpCas9	negative selection	12014090
74381116	74381139	4	+	28162770	MONOMAC1	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.01646460141773254	[44]	[50]	0	hSpCas9	negative selection	12014091
74365296	74365319	4	+	28162770	MONOMAC1	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	1.1399981402180168	[56]	[143]	8	hSpCas9	negative selection	12014092
74365329	74365352	4	+	28162770	MONOMAC1	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.8974765652006459	[77]	[47]	-6	hSpCas9	negative selection	12014093
74365354	74365377	4	-	28162770	MONOMAC1	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-0.9240183526531378	[47]	[28]	-6	hSpCas9	negative selection	12014094
74379489	74379512	4	-	28162770	MONOMAC1	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.48506681207213437	[133]	[214]	5	hSpCas9	negative selection	12014095
74381093	74381116	4	+	28162770	MONOMAC1	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	0.2473752543528036	[315]	[429]	2	hSpCas9	negative selection	12014096
74381018	74381041	4	+	28162770	MONOMAC1	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.014172789909743466	[295]	[335]	0	hSpCas9	negative selection	12014097
74365313	74365336	4	-	28162770	OCIAML2	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.00382810096785402	[141]	[784]	0	hSpCas9	negative selection	12183454
74379470	74379493	4	-	28162770	OCIAML2	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.2646954105427894	[43]	[292]	2	hSpCas9	negative selection	12183455
74381031	74381054	4	-	28162770	OCIAML2	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	0.6040960670429223	[86]	[732]	6	hSpCas9	negative selection	12183456
74381116	74381139	4	+	28162770	OCIAML2	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	0.3481298600876924	[17]	[126]	3	hSpCas9	negative selection	12183457
74365296	74365319	4	+	28162770	OCIAML2	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	0.48714193936854133	[12]	[100]	5	hSpCas9	negative selection	12183458
74365329	74365352	4	+	28162770	OCIAML2	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-0.777607578663552	[29]	[96]	-5	hSpCas9	negative selection	12183459
74365354	74365377	4	-	28162770	OCIAML2	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	-0.470629825242161	[17]	[71]	-4	hSpCas9	negative selection	12183460
74379489	74379512	4	-	28162770	OCIAML2	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	0.019175442438654988	[46]	[263]	0	hSpCas9	negative selection	12183461
74381093	74381116	4	+	28162770	OCIAML2	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	0.12474929142433333	[91]	[555]	1	hSpCas9	negative selection	12183462
74381018	74381041	4	+	28162770	OCIAML2	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.22600745652224785	[91]	[435]	-2	hSpCas9	negative selection	12183463
74365313	74365336	4	-	28162770	OCIAML3	viability	CATCTCCATCCTCCTCCCCGCGG	EREG	ENSG00000124882	-0.538359610774249	[177]	[369]	-4	hSpCas9	negative selection	12352820
74379470	74379493	4	-	28162770	OCIAML3	viability	ATGGAATCACAGTTGTACTGAGG	EREG	ENSG00000124882	0.5759173611181492	[47]	[215]	5	hSpCas9	negative selection	12352821
74381031	74381054	4	-	28162770	OCIAML3	viability	ATTGACACTTGAGCCACACGTGG	EREG	ENSG00000124882	1.0091594557745835	[104]	[637]	8	hSpCas9	negative selection	12352822
74381116	74381139	4	+	28162770	OCIAML3	viability	ACATGAGTCAAAACTACTGCAGG	EREG	ENSG00000124882	-0.7639326417664754	[17]	[31]	-5	hSpCas9	negative selection	12352823
74365296	74365319	4	+	28162770	OCIAML3	viability	GCTCCCATCGCCGATGACCGCGG	EREG	ENSG00000124882	-0.9463093842550443	[29]	[46]	-6	hSpCas9	negative selection	12352824
74365329	74365352	4	+	28162770	OCIAML3	viability	GGAGATGCTCTGTGCCGGCAGGG	EREG	ENSG00000124882	-1.1906519460929548	[30]	[40]	-7	hSpCas9	negative selection	12352825
74365354	74365377	4	-	28162770	OCIAML3	viability	CCCAGGCAGAGCAGCAGCGCAGG	EREG	ENSG00000124882	1.569738786189025	[25]	[232]	9	hSpCas9	negative selection	12352826
74379489	74379512	4	-	28162770	OCIAML3	viability	GACTCTCCTGGGATACATGATGG	EREG	ENSG00000124882	-0.9921713210386108	[84]	[128]	-6	hSpCas9	negative selection	12352827
74381093	74381116	4	+	28162770	OCIAML3	viability	TGGACAGTGCATCTATCTGGTGG	EREG	ENSG00000124882	0.32170680567136145	[162]	[614]	3	hSpCas9	negative selection	12352828
74381018	74381041	4	+	28162770	OCIAML3	viability	GACAGAAGACAATCCACGTGTGG	EREG	ENSG00000124882	-0.24654445332966335	[111]	[284]	-2	hSpCas9	negative selection	12352829