| 42830852 | 42830875 | 1 | + | 26472758 | Jiyoye | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -1.0953249590233096 | [33] | [11] | -6 | hSpCas9 | negative selection | 51594 | 42830980 | 42831003 | 1 | + | 26472758 | Jiyoye | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.072990929203673 | [218] | [156] | 0 | hSpCas9 | negative selection | 51595 | 42830908 | 42830931 | 1 | + | 26472758 | Jiyoye | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.29396477105788266 | [211] | [195] | 2 | hSpCas9 | negative selection | 51596 | 42830951 | 42830974 | 1 | + | 26472758 | Jiyoye | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 2.0249278173446994 | [28] | [88] | 8 | hSpCas9 | negative selection | 51597 | 42830490 | 42830513 | 1 | - | 26472758 | Jiyoye | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -2.014288386932403 | [224] | [41] | -8 | hSpCas9 | negative selection | 51598 | 42830508 | 42830531 | 1 | - | 26472758 | Jiyoye | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.731064992726522 | [146] | [183] | 5 | hSpCas9 | negative selection | 51599 | 42830778 | 42830801 | 1 | + | 26472758 | Jiyoye | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.025016838812037534 | [281] | [208] | 0 | hSpCas9 | negative selection | 51600 | 42830790 | 42830813 | 1 | + | 26472758 | Jiyoye | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.7165034396136022 | [183] | [227] | 5 | hSpCas9 | negative selection | 51601 | 42830893 | 42830916 | 1 | - | 26472758 | Jiyoye | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.5722346277763697 | [65] | [73] | 4 | hSpCas9 | negative selection | 51602 | 42830852 | 42830875 | 1 | + | 26472758 | KBM7 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 2.0803938355107543 | [91,39] | [256,9] | 9 | hSpCas9 | negative selection | 242712 | 42830980 | 42831003 | 1 | + | 26472758 | KBM7 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.33586708698141443 | [384,368] | [236,212] | 3 | hSpCas9 | negative selection | 242713 | 42830908 | 42830931 | 1 | + | 26472758 | KBM7 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.011003249737059018 | [1107,528] | [419,335] | 0 | hSpCas9 | negative selection | 242714 | 42830951 | 42830974 | 1 | + | 26472758 | KBM7 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.27330133381397637 | [393,278] | [95,158] | -3 | hSpCas9 | negative selection | 242715 | 42830490 | 42830513 | 1 | - | 26472758 | KBM7 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -1.7627069648116138 | [1390,1061] | [178,158] | -8 | hSpCas9 | negative selection | 242716 | 42830508 | 42830531 | 1 | - | 26472758 | KBM7 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | -0.15267220689386465 | [712,511] | [227,280] | -1 | hSpCas9 | negative selection | 242717 | 42830778 | 42830801 | 1 | + | 26472758 | KBM7 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.3815872966923799 | [1123,740] | [618,510] | 4 | hSpCas9 | negative selection | 242718 | 42830790 | 42830813 | 1 | + | 26472758 | KBM7 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.0772705366885218 | [1783,1702] | [1111,647] | 0 | hSpCas9 | negative selection | 242719 | 42830893 | 42830916 | 1 | - | 26472758 | KBM7 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 1.1816509904341634 | [474,311] | [160,637] | 9 | hSpCas9 | negative selection | 242720 | 42830852 | 42830875 | 1 | + | 26472758 | Raji | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 5.692346036094756 | [0] | [11] | 9 | hSpCas9 | negative selection | 433830 | 42830980 | 42831003 | 1 | + | 26472758 | Raji | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.1395639411227492 | [265] | [67] | 1 | hSpCas9 | negative selection | 433831 | 42830908 | 42830931 | 1 | + | 26472758 | Raji | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | -0.13692366239128895 | [397] | [83] | -1 | hSpCas9 | negative selection | 433832 | 42830951 | 42830974 | 1 | + | 26472758 | Raji | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 1.2040595547852733 | [100] | [53] | 9 | hSpCas9 | negative selection | 433833 | 42830490 | 42830513 | 1 | - | 26472758 | Raji | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -2.5146682840827768 | [393] | [15] | -9 | hSpCas9 | negative selection | 433834 | 42830508 | 42830531 | 1 | - | 26472758 | Raji | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.102825253411295 | [316] | [78] | 1 | hSpCas9 | negative selection | 433835 | 42830778 | 42830801 | 1 | + | 26472758 | Raji | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.2946151171296312 | [533] | [151] | 2 | hSpCas9 | negative selection | 433836 | 42830790 | 42830813 | 1 | + | 26472758 | Raji | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | -0.850388229237103 | [908] | [116] | -6 | hSpCas9 | negative selection | 433837 | 42830893 | 42830916 | 1 | - | 26472758 | Raji | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.6126188436240216 | [185] | [65] | 6 | hSpCas9 | negative selection | 433838 | 42830852 | 42830875 | 1 | + | 26472758 | K562 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -0.5737429493477402 | [133] | [75] | -4 | hSpCas9 | negative selection | 624948 | 42830980 | 42831003 | 1 | + | 26472758 | K562 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 1.4845772668114752 | [195] | [462] | 9 | hSpCas9 | negative selection | 624949 | 42830908 | 42830931 | 1 | + | 26472758 | K562 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | -0.6710971145563686 | [712] | [377] | -4 | hSpCas9 | negative selection | 624950 | 42830951 | 42830974 | 1 | + | 26472758 | K562 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.6271329068673999 | [246] | [134] | -4 | hSpCas9 | negative selection | 624951 | 42830490 | 42830513 | 1 | - | 26472758 | K562 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -4.107649227292913 | [918] | [44] | -9 | hSpCas9 | negative selection | 624952 | 42830508 | 42830531 | 1 | - | 26472758 | K562 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.2163361856984068 | [414] | [406] | 1 | hSpCas9 | negative selection | 624953 | 42830778 | 42830801 | 1 | + | 26472758 | K562 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.42833700118825924 | [683] | [776] | 3 | hSpCas9 | negative selection | 624954 | 42830790 | 42830813 | 1 | + | 26472758 | K562 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.22813107266151667 | [1157] | [1144] | 1 | hSpCas9 | negative selection | 624955 | 42830893 | 42830916 | 1 | - | 26472758 | K562 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | -0.3302754376008822 | [349] | [234] | -2 | hSpCas9 | negative selection | 624956 | 42830778 | 42830801 | 1 | + | 26627737 | DLD1 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.37592786513149057 | [172] | [51,50,24] | -4 | hSpCas9 | negative selection | 771483 | 42831025 | 42831048 | 1 | + | 26627737 | DLD1 | viability | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.7872394041812322 | [672] | [77,209,86] | -6 | hSpCas9 | negative selection | 771484 | 42830778 | 42830801 | 1 | + | 26627737 | GBM cells | viability after 5 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.16947310009456462 | [107] | [47,54] | -3 | hSpCas9 | negative selection | 853798 | 42831025 | 42831048 | 1 | + | 26627737 | GBM cells | viability after 5 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.9096318809505406 | [302] | [93,78] | -8 | hSpCas9 | negative selection | 853799 | 42830778 | 42830801 | 1 | + | 26627737 | GBM cells | viability after 13 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.257858059859025 | [107] | [64,35] | -3 | hSpCas9 | negative selection | 936113 | 42831025 | 42831048 | 1 | + | 26627737 | GBM cells | viability after 13 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.8154249462041255 | [302] | [104,83] | -7 | hSpCas9 | negative selection | 936114 | 42830778 | 42830801 | 1 | + | 26627737 | GBM cells | viability after 21 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -1.9720446042671678 | [107] | [15,13] | -9 | hSpCas9 | negative selection | 1018428 | 42831025 | 42831048 | 1 | + | 26627737 | GBM cells | viability after 21 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.666823188202768 | [302] | [110,96] | -5 | hSpCas9 | negative selection | 1018429 | 42830778 | 42830801 | 1 | + | 26627737 | RPE1 | viability after 9 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.13483036425475312 | [984] | [365,170] | -1 | hSpCas9 | negative selection | 1100743 | 42831025 | 42831048 | 1 | + | 26627737 | RPE1 | viability after 9 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.3284590328689988 | [1489] | [336,415] | -2 | hSpCas9 | negative selection | 1100744 | 42830778 | 42830801 | 1 | + | 26627737 | RPE1 | viability after 12 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.06587366337858752 | [984] | [429,114] | 0 | hSpCas9 | negative selection | 1183058 | 42831025 | 42831048 | 1 | + | 26627737 | RPE1 | viability after 12 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.7816838766155502 | [1489] | [261,201] | -5 | hSpCas9 | negative selection | 1183059 | 42830778 | 42830801 | 1 | + | 26627737 | RPE1 | viability after 15 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.42619860981432783 | [984] | [576,178] | 2 | hSpCas9 | negative selection | 1265373 | 42831025 | 42831048 | 1 | + | 26627737 | RPE1 | viability after 15 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -1.5051605061364022 | [1489] | [92,201] | -7 | hSpCas9 | negative selection | 1265374 | 42830778 | 42830801 | 1 | + | 26627737 | RPE1 | viability after 18 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.47634595617082676 | [984] | [265,110] | -3 | hSpCas9 | negative selection | 1347688 | 42831025 | 42831048 | 1 | + | 26627737 | RPE1 | viability after 18 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.963169758360917 | [1489] | [198,213] | -6 | hSpCas9 | negative selection | 1347689 | 42830778 | 42830801 | 1 | + | 26627737 | HeLa | viability after 8 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -1.2738944867227722 | [317] | [68,58,46] | -8 | hSpCas9 | negative selection | 1430003 | 42831025 | 42831048 | 1 | + | 26627737 | HeLa | viability after 8 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -1.6435680143779354 | [839] | [168,99,94] | -9 | hSpCas9 | negative selection | 1430004 | 42830778 | 42830801 | 1 | + | 26627737 | HeLa | viability after 12 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.5737202815918342 | [317] | [4,54,205] | -5 | hSpCas9 | negative selection | 1512318 | 42831025 | 42831048 | 1 | + | 26627737 | HeLa | viability after 12 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.9664054533219584 | [839] | [122,237,163] | -7 | hSpCas9 | negative selection | 1512319 | 42830778 | 42830801 | 1 | + | 26627737 | HeLa | viability after 15 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -1.5593717680895036 | [317] | [0,30,104] | -8 | hSpCas9 | negative selection | 1594633 | 42831025 | 42831048 | 1 | + | 26627737 | HeLa | viability after 15 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.44561442167148835 | [839] | [349,295,93] | -4 | hSpCas9 | negative selection | 1594634 | 42830778 | 42830801 | 1 | + | 26627737 | HeLa | viability after 18 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -1.5764590854560483 | [317] | [0,23,104] | -8 | hSpCas9 | negative selection | 1676948 | 42831025 | 42831048 | 1 | + | 26627737 | HeLa | viability after 18 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.40632287266889366 | [839] | [241,252,93] | -4 | hSpCas9 | negative selection | 1676949 | 42830778 | 42830801 | 1 | + | 26627737 | HCT116 | viability after 6 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.4815965672019161 | [496] | [72,128] | 2 | hSpCas9 | negative selection | 1759263 | 42831025 | 42831048 | 1 | + | 26627737 | HCT116 | viability after 6 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -1.6099494624537285 | [1022] | [62,46] | -7 | hSpCas9 | negative selection | 1759264 | 42830778 | 42830801 | 1 | + | 26627737 | HCT116 | viability after 8 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.23024043844569056 | [243] | [175,100,195] | 2 | hSpCas9 | negative selection | 1841578 | 42831025 | 42831048 | 1 | + | 26627737 | HCT116 | viability after 8 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.6092733875124037 | [553] | [160,185,251] | -6 | hSpCas9 | negative selection | 1841579 | 42830778 | 42830801 | 1 | + | 26627737 | HCT116 | viability after 9 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.5486712991072448 | [496] | [68,292] | 4 | hSpCas9 | negative selection | 1923893 | 42831025 | 42831048 | 1 | + | 26627737 | HCT116 | viability after 9 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | 0.04954124711349395 | [1022] | [213,336] | 0 | hSpCas9 | negative selection | 1923894 | 42830778 | 42830801 | 1 | + | 26627737 | HCT116 | viability after 12 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.43709302282214596 | [243] | [87,105,90] | -5 | hSpCas9 | negative selection | 2006208 | 42831025 | 42831048 | 1 | + | 26627737 | HCT116 | viability after 12 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.2466478858223341 | [553] | [193,340,207] | -3 | hSpCas9 | negative selection | 2006209 | 42830778 | 42830801 | 1 | + | 26627737 | HCT116 | viability after 15 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.09987579573847488 | [243] | [143,91,212] | 1 | hSpCas9 | negative selection | 2088523 | 42831025 | 42831048 | 1 | + | 26627737 | HCT116 | viability after 15 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.2710538219680002 | [553] | [222,378,184] | -3 | hSpCas9 | negative selection | 2088524 | 42830778 | 42830801 | 1 | + | 26627737 | HCT116 | viability after 18 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.5699606701533864 | [243] | [118,123,290] | 5 | hSpCas9 | negative selection | 2170838 | 42831025 | 42831048 | 1 | + | 26627737 | HCT116 | viability after 18 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | 0.06541604623417607 | [553] | [204,351,278] | 0 | hSpCas9 | negative selection | 2170839 | 42825429 | 42825452 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AACCACTGAGTATGACTGACCGG | ERMAP | ENSG00000164010 | 2.360422455528327 | [91,124] | [186,54] | 7 | dCas9-VP64 | positive selection | 2450323 | 42825452 | 42825475 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAGGAGGCTCCCAAAAATGAGGG | ERMAP | ENSG00000164010 | -0.04656077473133008 | [29,116] | [3,27] | 0 | dCas9-VP64 | positive selection | 2450324 | 42825410 | 42825433 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGGCAAACGTGCCTCCTACCCGG | ERMAP | ENSG00000164010 | 1.0069428468357031 | [63,109] | [56,18] | 4 | dCas9-VP64 | positive selection | 2450325 | 42817500 | 42817523 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AATATAACGGGAAAAAGCTTTGG | ERMAP | ENSG00000164010 | 1.0267449274007947 | [22,5] | [7,3] | 4 | dCas9-VP64 | positive selection | 2475846 | 42817528 | 42817551 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAACAGCTACTAGGTTTTAGAGG | ERMAP | ENSG00000164010 | -2.0937815478533444 | [360,131] | [8,15] | -9 | dCas9-VP64 | positive selection | 2475847 | 42817552 | 42817575 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGAGATCCGAATCCTGGAATTGG | ERMAP | ENSG00000164010 | 3.0908512417264173 | [94,133] | [33,412] | 8 | dCas9-VP64 | positive selection | 2475848 | 42825429 | 42825452 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AACCACTGAGTATGACTGACCGG | ERMAP | ENSG00000164010 | -1.1763700955439718 | [380,182] | [55,25] | -9 | dCas9-VP64 | positive selection | 2545578 | 42825452 | 42825475 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAGGAGGCTCCCAAAAATGAGGG | ERMAP | ENSG00000164010 | -0.38365040169226705 | [16,145] | [11,26] | -4 | dCas9-VP64 | positive selection | 2545579 | 42825410 | 42825433 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGGCAAACGTGCCTCCTACCCGG | ERMAP | ENSG00000164010 | 0.15905494767671996 | [182,16] | [67,6] | 1 | dCas9-VP64 | positive selection | 2545580 | 42817500 | 42817523 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AATATAACGGGAAAAAGCTTTGG | ERMAP | ENSG00000164010 | -0.21161803054532657 | [302,55] | [38,61] | -2 | dCas9-VP64 | positive selection | 2571101 | 42817528 | 42817551 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAACAGCTACTAGGTTTTAGAGG | ERMAP | ENSG00000164010 | 0.09720619201930407 | [46,159] | [25,44] | 0 | dCas9-VP64 | positive selection | 2571102 | 42817552 | 42817575 | 1 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGAGATCCGAATCCTGGAATTGG | ERMAP | ENSG00000164010 | -0.13520874391027282 | [130,240] | [38,68] | -1 | dCas9-VP64 | positive selection | 2571103 | 42830981 | 42831004 | 1 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.8337863113647815 | [3,3] | [2,0] | -8 | hSpCas9 | positive selection | 2986332 | 42830779 | 42830802 | 1 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.2134571808456823 | [2,3] | [4,2] | 4 | hSpCas9 | positive selection | 2986333 | 42830793 | 42830816 | 1 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGCCCCCTAGTAGGGCCACGTGG | ERMAP | ENSG00000164010 | -0.5650624620505829 | [2,1] | [1,0] | -7 | hSpCas9 | positive selection | 2986334 | 42830981 | 42831004 | 1 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.06617792817130914 | [3,3] | [3,2] | 1 | hSpCas9 | positive selection | 3054190 | 42830779 | 42830802 | 1 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.45860403409477407 | [2,2] | [3,2] | 7 | hSpCas9 | positive selection | 3054191 | 42830793 | 42830816 | 1 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGCCCCCTAGTAGGGCCACGTGG | ERMAP | ENSG00000164010 | -0.49076381940114966 | [2,2] | [1,0] | -7 | hSpCas9 | positive selection | 3054192 | 42831018 | 42831041 | 1 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 1.0207335500680548 | [60,89] | [0,0] | 4 | hSpCas9 | positive selection | 3348323 | 42831052 | 42831075 | 1 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.2900724052266669 | [196,176] | [0,0] | -2 | hSpCas9 | positive selection | 3348324 | 42830980 | 42831003 | 1 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 1.605269184363 | [] | [] | 6 | hSpCas9 | negative selection | 3423159 | 42830778 | 42830801 | 1 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 1.4192146295298 | [] | [] | 5 | hSpCas9 | negative selection | 3423160 | 42830793 | 42830816 | 1 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGCCCCCTAGTAGGGCCACGTGG | ERMAP | ENSG00000164010 | 0.139640740495444 | [] | [] | 0 | hSpCas9 | negative selection | 3423161 | 42830980 | 42831003 | 1 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 1.68422265918694 | [] | [] | 2 | hSpCas9 | negative selection | 3504173 | 42830793 | 42830816 | 1 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGCCCCCTAGTAGGGCCACGTGG | ERMAP | ENSG00000164010 | 6.22566170172746 | [] | [] | 9 | hSpCas9 | negative selection | 3504174 | 42830778 | 42830801 | 1 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 3.65208770726296 | [] | [] | 6 | hSpCas9 | negative selection | 3504175 | 42830508 | 42830531 | 1 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 2.49351134986608 | [] | [] | 4 | hSpCas9 | negative selection | 3504176 | 42830496 | 42830519 | 1 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACAGCCGGAGGAAGACGAGAGGG | ERMAP | ENSG00000164010 | -0.693859973335168 | [] | [] | -1 | hSpCas9 | negative selection | 3504177 | 42830980 | 42831003 | 1 | + | 26780180 | A375 | viability (Avana lentiGuide) | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -2.44331565213886 | [] | [] | -4 | hSpCas9 | negative selection | 3612832 | 42830793 | 42830816 | 1 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGCCCCCTAGTAGGGCCACGTGG | ERMAP | ENSG00000164010 | 8.46755226138723 | [] | [] | 6 | hSpCas9 | negative selection | 3612833 | 42830778 | 42830801 | 1 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.76358572656678 | [] | [] | 0 | hSpCas9 | negative selection | 3612834 | 42830508 | 42830531 | 1 | - | 26780180 | A375 | viability (Avana lentiGuide) | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.92394694339458 | [] | [] | 1 | hSpCas9 | negative selection | 3612835 | 42830496 | 42830519 | 1 | - | 26780180 | A375 | viability (Avana lentiGuide) | ACAGCCGGAGGAAGACGAGAGGG | ERMAP | ENSG00000164010 | 6.47277269808889 | [] | [] | 5 | hSpCas9 | negative selection | 3612836 | 42830980 | 42831003 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.007761200716069906 | [5] | [5,3] | 0 | hSpCas9 | positive selection | 3721491 | 42830793 | 42830816 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGCCCCCTAGTAGGGCCACGTGG | ERMAP | ENSG00000164010 | 0.35225481756192045 | [3] | [6,4] | 9 | hSpCas9 | positive selection | 3721492 | 42830778 | 42830801 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.25558819751227585 | [5] | [5,6] | 7 | hSpCas9 | positive selection | 3721493 | 42830508 | 42830531 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.1838524869667944 | [5] | [6,5] | 5 | hSpCas9 | positive selection | 3721494 | 42830496 | 42830519 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACAGCCGGAGGAAGACGAGAGGG | ERMAP | ENSG00000164010 | -0.2151956394466169 | [5] | [4,4] | -3 | hSpCas9 | positive selection | 3721495 | 42830980 | 42831003 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.1810303082608528 | [5] | [2,4] | -3 | hSpCas9 | positive selection | 3830098 | 42830793 | 42830816 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGCCCCCTAGTAGGGCCACGTGG | ERMAP | ENSG00000164010 | -0.568039529415221 | [5] | [1,3] | -6 | hSpCas9 | positive selection | 3830099 | 42830778 | 42830801 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.1863601760798188 | [5] | [5,5] | 4 | hSpCas9 | positive selection | 3830100 | 42830508 | 42830531 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.22397857301748197 | [6] | [5,6] | 6 | hSpCas9 | positive selection | 3830101 | 42830496 | 42830519 | 1 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACAGCCGGAGGAAGACGAGAGGG | ERMAP | ENSG00000164010 | -0.6102337732831937 | [6] | [1,4] | -7 | hSpCas9 | positive selection | 3830102 | 42831018 | 42831041 | 1 | + | 26780180 | A375 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.717559221987305 | [] | [] | 2 | hSpCas9 | negative selection | 3937447 | 42831052 | 42831075 | 1 | + | 26780180 | A375 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.261530447802869 | [] | [] | 0 | hSpCas9 | negative selection | 3937448 | 42831018 | 42831041 | 1 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.79117660552871 | [] | [] | 3 | hSpCas9 | negative selection | 4045413 | 42831052 | 42831075 | 1 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.155875261000928 | [] | [] | 0 | hSpCas9 | negative selection | 4045414 | 42831018 | 42831041 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.14562363281047824 | [2] | [2,0] | -3 | hSpCas9 | positive selection | 4269189 | 42831052 | 42831075 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.2189875387539166 | [3] | [3,2] | 4 | hSpCas9 | positive selection | 4269190 | 42830792 | 42830814 | 1 | + | 27760321 | OCIAML3 | viability | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | -0.07291762747890074 | [291,237] | [136,272] | -1 | hSpCas9 | negative selection | 4398312 | 42830952 | 42830974 | 1 | + | 27760321 | OCIAML3 | viability | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.19785794670493514 | [411,346] | [326,354] | 2 | hSpCas9 | negative selection | 4398313 | 42831021 | 42831043 | 1 | - | 27760321 | OCIAML3 | viability | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.4470141947627101 | [841,697] | [779,865] | 5 | hSpCas9 | negative selection | 4398314 | 42831053 | 42831075 | 1 | + | 27760321 | OCIAML3 | viability | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.034544812612155196 | [533,462] | [419,369] | 0 | hSpCas9 | negative selection | 4398315 | 42830792 | 42830814 | 1 | + | 27760321 | OCIAML2 | viability | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.5795265485907886 | [291,237] | [316,320] | 7 | hSpCas9 | negative selection | 4481775 | 42830952 | 42830974 | 1 | + | 27760321 | OCIAML2 | viability | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.0033153748008495076 | [411,346] | [220,415] | 0 | hSpCas9 | negative selection | 4481776 | 42831021 | 42831043 | 1 | - | 27760321 | OCIAML2 | viability | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.5532322223781784 | [841,697] | [824,1021] | 7 | hSpCas9 | negative selection | 4481777 | 42831053 | 42831075 | 1 | + | 27760321 | OCIAML2 | viability | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.1465066359007306 | [533,462] | [411,488] | 2 | hSpCas9 | negative selection | 4481778 | 42830792 | 42830814 | 1 | + | 27760321 | MV411 | viability | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.8804726170472628 | [291,237] | [203,494] | 6 | hSpCas9 | negative selection | 4565238 | 42830952 | 42830974 | 1 | + | 27760321 | MV411 | viability | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 1.3208086878014589 | [411,346] | [444,890] | 8 | hSpCas9 | negative selection | 4565239 | 42831021 | 42831043 | 1 | - | 27760321 | MV411 | viability | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.32201405390649696 | [841,697] | [635,626] | 2 | hSpCas9 | negative selection | 4565240 | 42831053 | 42831075 | 1 | + | 27760321 | MV411 | viability | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.4168693543386685 | [533,462] | [493,353] | 3 | hSpCas9 | negative selection | 4565241 | 42830792 | 42830814 | 1 | + | 27760321 | HL60 | viability | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.4649463909521298 | [291,237] | [239,357] | 5 | hSpCas9 | negative selection | 4648701 | 42830952 | 42830974 | 1 | + | 27760321 | HL60 | viability | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.36097840893850364 | [411,346] | [189,293] | -4 | hSpCas9 | negative selection | 4648702 | 42831021 | 42831043 | 1 | - | 27760321 | HL60 | viability | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | -0.14653827335742575 | [841,697] | [573,556] | -2 | hSpCas9 | negative selection | 4648703 | 42831053 | 42831075 | 1 | + | 27760321 | HL60 | viability | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 1.2764141926369972 | [533,462] | [913,1057] | 9 | hSpCas9 | negative selection | 4648704 | 42830792 | 42830814 | 1 | + | 27760321 | HT1080 | viability | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.09553419819424624 | [237,185] | [126,49] | 0 | hSpCas9 | negative selection | 4732164 | 42830952 | 42830974 | 1 | + | 27760321 | HT1080 | viability | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.5352014471815192 | [346,270] | [125,39] | -2 | hSpCas9 | negative selection | 4732165 | 42831021 | 42831043 | 1 | - | 27760321 | HT1080 | viability | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 1.471184777534847 | [697,544] | [421,975] | 7 | hSpCas9 | negative selection | 4732166 | 42831053 | 42831075 | 1 | + | 27760321 | HT1080 | viability | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.040795645417486925 | [462,360] | [122,218] | 0 | hSpCas9 | negative selection | 4732167 | 42830792 | 42830814 | 1 | + | 27760321 | HT29 | viability after 7 days | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.25294477598422094 | [237,185] | [471,324,201] | 4 | hSpCas9 | negative selection | 4815627 | 42830952 | 42830974 | 1 | + | 27760321 | HT29 | viability after 7 days | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.06984885329829826 | [346,270] | [434,591,231] | 1 | hSpCas9 | negative selection | 4815628 | 42831021 | 42831043 | 1 | - | 27760321 | HT29 | viability after 7 days | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.5431048875599422 | [697,544] | [1528,964,1052] | 8 | hSpCas9 | negative selection | 4815629 | 42831053 | 42831075 | 1 | + | 27760321 | HT29 | viability after 7 days | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.1969507574071421 | [462,360] | [622,787,417] | 3 | hSpCas9 | negative selection | 4815630 | 42830792 | 42830814 | 1 | + | 27760321 | HT29 | viability after 25 days | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.10487203782170407 | [237,185] | [192,198,408] | 1 | hSpCas9 | negative selection | 4899090 | 42830952 | 42830974 | 1 | + | 27760321 | HT29 | viability after 25 days | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.3556101047165344 | [346,270] | [212,695,461] | 4 | hSpCas9 | negative selection | 4899091 | 42831021 | 42831043 | 1 | - | 27760321 | HT29 | viability after 25 days | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.6963974192344284 | [697,544] | [1165,1281,984] | 7 | hSpCas9 | negative selection | 4899092 | 42831053 | 42831075 | 1 | + | 27760321 | HT29 | viability after 25 days | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.129863793942031 | [462,360] | [601,380,560] | 1 | hSpCas9 | negative selection | 4899093 | 42830792 | 42830814 | 1 | + | 27760321 | HT29 | viability after 22 days | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.5290079341693721 | [237,185] | [220,549,292] | 6 | hSpCas9 | negative selection | 4982553 | 42830952 | 42830974 | 1 | + | 27760321 | HT29 | viability after 22 days | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.03805885516235838 | [346,270] | [141,535,428] | 0 | hSpCas9 | negative selection | 4982554 | 42831021 | 42831043 | 1 | - | 27760321 | HT29 | viability after 22 days | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.9527355477261128 | [697,544] | [1960,1181,1009] | 9 | hSpCas9 | negative selection | 4982555 | 42831053 | 42831075 | 1 | + | 27760321 | HT29 | viability after 22 days | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.12212186519756171 | [462,360] | [540,428,584] | 1 | hSpCas9 | negative selection | 4982556 | 42830792 | 42830814 | 1 | + | 27760321 | HT29 | viability after 19 days | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.794023951793368 | [237,185] | [371,303,573] | 7 | hSpCas9 | negative selection | 5066016 | 42830952 | 42830974 | 1 | + | 27760321 | HT29 | viability after 19 days | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.0048295237776716515 | [346,270] | [244,441,357] | 0 | hSpCas9 | negative selection | 5066017 | 42831021 | 42831043 | 1 | - | 27760321 | HT29 | viability after 19 days | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.9451001672077357 | [697,544] | [1241,1548,1302] | 8 | hSpCas9 | negative selection | 5066018 | 42831053 | 42831075 | 1 | + | 27760321 | HT29 | viability after 19 days | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.2176970486442983 | [462,360] | [430,275,506] | -2 | hSpCas9 | negative selection | 5066019 | 42830792 | 42830814 | 1 | + | 27760321 | HT29 | viability after 16 days | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.459283566708835 | [237,185] | [179,345,437] | 5 | hSpCas9 | negative selection | 5149479 | 42830952 | 42830974 | 1 | + | 27760321 | HT29 | viability after 16 days | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.26999067422636364 | [346,270] | [262,455,515] | 3 | hSpCas9 | negative selection | 5149480 | 42831021 | 42831043 | 1 | - | 27760321 | HT29 | viability after 16 days | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.5752326717342144 | [697,544] | [765,1165,1146] | 6 | hSpCas9 | negative selection | 5149481 | 42831053 | 42831075 | 1 | + | 27760321 | HT29 | viability after 16 days | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.31495718241911175 | [462,360] | [837,535,371] | 3 | hSpCas9 | negative selection | 5149482 | 42830792 | 42830814 | 1 | + | 27760321 | HT29 | viability after 13 days | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.5846952644562254 | [237,185] | [573,195,337] | 7 | hSpCas9 | negative selection | 5232942 | 42830952 | 42830974 | 1 | + | 27760321 | HT29 | viability after 13 days | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.40589231295422223 | [346,270] | [491,495,438] | 5 | hSpCas9 | negative selection | 5232943 | 42831021 | 42831043 | 1 | - | 27760321 | HT29 | viability after 13 days | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.832633446579909 | [697,544] | [1143,1485,1225] | 9 | hSpCas9 | negative selection | 5232944 | 42831053 | 42831075 | 1 | + | 27760321 | HT29 | viability after 13 days | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.0525206863570824 | [462,360] | [458,498,526] | 0 | hSpCas9 | negative selection | 5232945 | 42830792 | 42830814 | 1 | + | 27760321 | HT29 | viability after 10 days | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.4557600961195113 | [237,185] | [321,338,425] | 6 | hSpCas9 | negative selection | 5316405 | 42830952 | 42830974 | 1 | + | 27760321 | HT29 | viability after 10 days | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.36402433816002144 | [346,270] | [514,616,363] | 5 | hSpCas9 | negative selection | 5316406 | 42831021 | 42831043 | 1 | - | 27760321 | HT29 | viability after 10 days | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 0.6105712990653596 | [697,544] | [1178,1280,1098] | 8 | hSpCas9 | negative selection | 5316407 | 42831053 | 42831075 | 1 | + | 27760321 | HT29 | viability after 10 days | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.2154500826275553 | [462,360] | [925,538,330] | 3 | hSpCas9 | negative selection | 5316408 | 42830792 | 42830814 | 1 | + | 27760321 | MOLM13 | viability | TCCACGTGGCCCTACTAGGGGG | ERMAP | ENSG00000164010 | 0.9302036334055447 | [291,237] | [505,93] | 6 | hSpCas9 | negative selection | 5399868 | 42830952 | 42830974 | 1 | + | 27760321 | MOLM13 | viability | GATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.471334834061316 | [411,346] | [527,97] | 3 | hSpCas9 | negative selection | 5399869 | 42831021 | 42831043 | 1 | - | 27760321 | MOLM13 | viability | GTCCTCAAGGCGCACGTCAAGG | ERMAP | ENSG00000164010 | 1.5728516696405204 | [841,697] | [1424,1168] | 9 | hSpCas9 | negative selection | 5399870 | 42831053 | 42831075 | 1 | + | 27760321 | MOLM13 | viability | ACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.222325538148746 | [533,462] | [287,199] | -1 | hSpCas9 | negative selection | 5399871 | 42817361 | 42817384 | 1 | + | 27661255 | K562 | viability | GAGGCTTCCGCCCGCAGGAGCGG | ERMAP | ENSG00000164010 | 0.1963551411804101 | [1620,2117] | [1859,1568] | 6 | dCas9-KRAB | negative selection | 5468715 | 42817271 | 42817294 | 1 | - | 27661255 | K562 | viability | GCAGCGCTGGGTCCAGTGGTCGG | ERMAP | ENSG00000164010 | 0.11406181251006753 | [1089,1091] | [1001,892] | 4 | dCas9-KRAB | negative selection | 5468717 | 42817304 | 42817327 | 1 | - | 27661255 | K562 | viability | GCGGCCCCGCCCAGGACGAGGGG | ERMAP | ENSG00000164010 | 0.19233327208555417 | [1215,1513] | [1261,1222] | 6 | dCas9-KRAB | negative selection | 5468718 | 42817461 | 42817484 | 1 | + | 27661255 | K562 | viability | GGGCGGAGCCACACCGGGGTGGG | ERMAP | ENSG00000164010 | 0.03341563759808208 | [481,420] | [396,346] | 1 | dCas9-KRAB | negative selection | 5477803 | 42825537 | 42825560 | 1 | + | 27661255 | K562 | viability | GCGAGAAGGGAGTTCTGTGGGGG | ERMAP | ENSG00000164010 | 0.22035575940232896 | [794,772] | [770,694] | 7 | dCas9-KRAB | negative selection | 5477804 | 42817304 | 42817327 | 1 | - | 27661255 | K562 | viability | GCGGCCCCGCCCAGGACGAGGGG | ERMAP | ENSG00000164010 | 0.19233327208555417 | [1215,1513] | [1261,1222] | 6 | dCas9-KRAB | negative selection | 5477805 | 42825606 | 42825629 | 1 | - | 27661255 | K562 | viability | GAAGGCCTAGGGATGTGGGCCGG | ERMAP | ENSG00000164010 | 0.07457925220626271 | [458,570] | [498,373] | 2 | dCas9-KRAB | negative selection | 5477806 | 42831018 | 42831041 | 1 | + | 27260156 | BXPC3 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.0069364097771514865 | [234] | [200,296,240,248] | 0 | hSpCas9 | negative selection | 5541649 | 42831052 | 42831075 | 1 | + | 27260156 | BXPC3 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.04953019763026412 | [776] | [902,760,810,884] | 1 | hSpCas9 | negative selection | 5541650 | 42831018 | 42831041 | 1 | + | 27260156 | A673 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.4221602930252609 | [234] | [418,352,411,329] | 8 | hSpCas9 | negative selection | 5662900 | 42831052 | 42831075 | 1 | + | 27260156 | A673 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.015041494466127125 | [776] | [1143,780,915,876] | 0 | hSpCas9 | negative selection | 5662901 | 42831018 | 42831041 | 1 | + | 27260156 | A375 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.08757724117229193 | [234] | [242,253,178,344] | -1 | hSpCas9 | negative selection | 5784151 | 42831052 | 42831075 | 1 | + | 27260156 | A375 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.23859458993784777 | [776] | [1049,1435,925,933] | 3 | hSpCas9 | negative selection | 5784152 | 42831018 | 42831041 | 1 | + | 27260156 | COLO741 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.1444432568347288 | [234] | [480,232,295] | 3 | hSpCas9 | negative selection | 5905402 | 42831052 | 42831075 | 1 | + | 27260156 | COLO741 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.02448189904000997 | [776] | [905,1020,991] | 0 | hSpCas9 | negative selection | 5905403 | 42831018 | 42831041 | 1 | + | 27260156 | CAL120 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.18699594784689721 | [234] | [489,243,288] | 2 | hSpCas9 | negative selection | 6026653 | 42831052 | 42831075 | 1 | + | 27260156 | CAL120 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.4563064278437168 | [776] | [1754,1202,1089] | 6 | hSpCas9 | negative selection | 6026654 | 42831018 | 42831041 | 1 | + | 27260156 | CADOES1 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.5894584226944634 | [234] | [299,189,501,322] | 8 | hSpCas9 | negative selection | 6147904 | 42831052 | 42831075 | 1 | + | 27260156 | CADOES1 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.4162798105140526 | [776] | [1195,846,840,972] | 7 | hSpCas9 | negative selection | 6147905 | 42831018 | 42831041 | 1 | + | 27260156 | EWS502 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.09417464887053906 | [234] | [137,249,224,336] | -2 | hSpCas9 | negative selection | 6269155 | 42831052 | 42831075 | 1 | + | 27260156 | EWS502 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.1727359572826339 | [776] | [717,930,958,1139] | 3 | hSpCas9 | negative selection | 6269156 | 42831018 | 42831041 | 1 | + | 27260156 | EW8 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.1412693341454565 | [234] | [214,173,304,129] | 2 | hSpCas9 | negative selection | 6390406 | 42831052 | 42831075 | 1 | + | 27260156 | EW8 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.2416089679473692 | [776] | [905,751,516,856] | 4 | hSpCas9 | negative selection | 6390407 | 42831018 | 42831041 | 1 | + | 27260156 | CORL105 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.10567107471180992 | [234] | [284,265,320,315] | 2 | hSpCas9 | negative selection | 6511657 | 42831052 | 42831075 | 1 | + | 27260156 | CORL105 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.09576683379084838 | [776] | [989,734,1176,1022] | 1 | hSpCas9 | negative selection | 6511658 | 42831018 | 42831041 | 1 | + | 27260156 | HS294T | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.13167144210867554 | [234] | [76,74,98,80] | -2 | hSpCas9 | negative selection | 6632908 | 42831052 | 42831075 | 1 | + | 27260156 | HS294T | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.0389562114545543 | [776] | [239,265,289,395] | 0 | hSpCas9 | negative selection | 6632909 | 42831018 | 42831041 | 1 | + | 27260156 | HCC44 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.41878377476788053 | [234] | [460,367,230,344] | 7 | hSpCas9 | negative selection | 6754159 | 42831052 | 42831075 | 1 | + | 27260156 | HCC44 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.01514437327031748 | [776] | [1249,654,1000,729] | 0 | hSpCas9 | negative selection | 6754160 | 42831018 | 42831041 | 1 | + | 27260156 | G402 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.3543793834021287 | [234] | [199,244,266,183] | -4 | hSpCas9 | negative selection | 6875410 | 42831052 | 42831075 | 1 | + | 27260156 | G402 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.6450880712472491 | [776] | [1371,1927,1113,1518] | 7 | hSpCas9 | negative selection | 6875411 | 42831018 | 42831041 | 1 | + | 27260156 | L33 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.20915809886374237 | [234] | [221,86,220,301] | 4 | hSpCas9 | negative selection | 6996661 | 42831052 | 42831075 | 1 | + | 27260156 | L33 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.017868511291776246 | [776] | [760,325,559,700] | 0 | hSpCas9 | negative selection | 6996662 | 42831018 | 42831041 | 1 | + | 27260156 | K562 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.309701230786778 | [234] | [256,196,387,194] | 4 | hSpCas9 | negative selection | 7117912 | 42831052 | 42831075 | 1 | + | 27260156 | K562 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.5508820151906593 | [776] | [760,1392,937,950] | 7 | hSpCas9 | negative selection | 7117913 | 42831018 | 42831041 | 1 | + | 27260156 | HT29 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.23983348337978694 | [234] | [432,410,290,237] | 5 | hSpCas9 | negative selection | 7239163 | 42831052 | 42831075 | 1 | + | 27260156 | HT29 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.08413744319071326 | [776] | [1137,1102,882,904] | 1 | hSpCas9 | negative selection | 7239164 | 42831018 | 42831041 | 1 | + | 27260156 | MHHES1 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.16037270146685878 | [234] | [278,149,453,280] | 3 | hSpCas9 | negative selection | 7360414 | 42831052 | 42831075 | 1 | + | 27260156 | MHHES1 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.06624037403731298 | [776] | [1019,1154,534,698] | -1 | hSpCas9 | negative selection | 7360415 | 42831018 | 42831041 | 1 | + | 27260156 | MEWO | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.7510735362975101 | [234] | [249,318,517] | 9 | hSpCas9 | negative selection | 7481665 | 42831052 | 42831075 | 1 | + | 27260156 | MEWO | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.09049587504436019 | [776] | [967,647,743] | 2 | hSpCas9 | negative selection | 7481666 | 42831018 | 42831041 | 1 | + | 27260156 | LNCAPCLONEFGC | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.18310411632801227 | [234] | [299,222,189,245] | 3 | hSpCas9 | negative selection | 7602916 | 42831052 | 42831075 | 1 | + | 27260156 | LNCAPCLONEFGC | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.4268485370985575 | [776] | [743,770,1359,985] | 6 | hSpCas9 | negative selection | 7602917 | 42831018 | 42831041 | 1 | + | 27260156 | PANC0327 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.24269158410808855 | [234] | [257,104,229,413] | 3 | hSpCas9 | negative selection | 7724167 | 42831052 | 42831075 | 1 | + | 27260156 | PANC0327 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.32081835117419155 | [776] | [983,923,739,801] | 5 | hSpCas9 | negative selection | 7724168 | 42831018 | 42831041 | 1 | + | 27260156 | NCIH2009 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.15158658778226908 | [234] | [294,302,287] | -2 | hSpCas9 | negative selection | 7845418 | 42831052 | 42831075 | 1 | + | 27260156 | NCIH2009 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.16983457415577585 | [776] | [1754,1059,954] | 2 | hSpCas9 | negative selection | 7845419 | 42831018 | 42831041 | 1 | + | 27260156 | NCIH1373 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.1863886933093668 | [234] | [338,199,146,68] | -2 | hSpCas9 | negative selection | 7966669 | 42831052 | 42831075 | 1 | + | 27260156 | NCIH1373 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.1655570795489989 | [776] | [952,709,964,346] | 1 | hSpCas9 | negative selection | 7966670 | 42831018 | 42831041 | 1 | + | 27260156 | PATU8902 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.2393718173664311 | [234] | [189,231,151,1118] | 2 | hSpCas9 | negative selection | 8087920 | 42831052 | 42831075 | 1 | + | 27260156 | PATU8902 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.33676583997112175 | [776] | [2068,1262,1314,736] | 3 | hSpCas9 | negative selection | 8087921 | 42831018 | 42831041 | 1 | + | 27260156 | PANC1 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.12381258228380188 | [234] | [229,277,256,136] | 2 | hSpCas9 | negative selection | 8209171 | 42831052 | 42831075 | 1 | + | 27260156 | PANC1 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.2078284024620315 | [776] | [802,798,829,661] | 3 | hSpCas9 | negative selection | 8209172 | 42831018 | 42831041 | 1 | + | 27260156 | PANC0813 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.12595045867091748 | [234] | [346,197,238,236] | -2 | hSpCas9 | negative selection | 8330422 | 42831052 | 42831075 | 1 | + | 27260156 | PANC0813 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.3697891544370393 | [776] | [1243,1357,1124,1003] | 6 | hSpCas9 | negative selection | 8330423 | 42831018 | 42831041 | 1 | + | 27260156 | RDES | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.06047609093124484 | [234] | [219,317,378,202] | 1 | hSpCas9 | negative selection | 8451673 | 42831052 | 42831075 | 1 | + | 27260156 | RDES | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.20600084496227933 | [776] | [825,980,1067,1309] | 3 | hSpCas9 | negative selection | 8451674 | 42831018 | 42831041 | 1 | + | 27260156 | PC3 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.21107233440784745 | [234] | [158,413,228,280] | 4 | hSpCas9 | negative selection | 8572924 | 42831052 | 42831075 | 1 | + | 27260156 | PC3 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.3343231152090944 | [776] | [631,895,1441,1183] | 7 | hSpCas9 | negative selection | 8572925 | 42831018 | 42831041 | 1 | + | 27260156 | PATU8988T | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.3539884845488299 | [234] | [268,360,316,213] | 6 | hSpCas9 | negative selection | 8694175 | 42831052 | 42831075 | 1 | + | 27260156 | PATU8988T | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.2334673636512119 | [776] | [1019,804,711,997] | 4 | hSpCas9 | negative selection | 8694176 | 42831018 | 42831041 | 1 | + | 27260156 | T47D | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.2088950994666008 | [234] | [334,279,367,283] | 4 | hSpCas9 | negative selection | 8815426 | 42831052 | 42831075 | 1 | + | 27260156 | T47D | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.18337178707757718 | [776] | [1025,904,1074,1117] | 4 | hSpCas9 | negative selection | 8815427 | 42831018 | 42831041 | 1 | + | 27260156 | SU8686 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.08012223182532796 | [234] | [297,176,221,296] | 1 | hSpCas9 | negative selection | 8936677 | 42831052 | 42831075 | 1 | + | 27260156 | SU8686 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.12479224079174644 | [776] | [826,628,1096,835] | 2 | hSpCas9 | negative selection | 8936678 | 42831018 | 42831041 | 1 | + | 27260156 | SKES1 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.3079679014200054 | [234] | [406,299,297,182] | 6 | hSpCas9 | negative selection | 9057928 | 42831052 | 42831075 | 1 | + | 27260156 | SKES1 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.08250312464070342 | [776] | [918,1031,754,630] | 1 | hSpCas9 | negative selection | 9057929 | 42831018 | 42831041 | 1 | + | 27260156 | TOV112D | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | -0.064259153465688 | [234] | [265,314,168,176] | -1 | hSpCas9 | negative selection | 9179179 | 42831052 | 42831075 | 1 | + | 27260156 | TOV112D | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.2665864682509431 | [776] | [1202,835,806,895] | 5 | hSpCas9 | negative selection | 9179180 | 42831018 | 42831041 | 1 | + | 27260156 | TC71 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.12305511597926189 | [234] | [313,215,319,242] | 3 | hSpCas9 | negative selection | 9300430 | 42831052 | 42831075 | 1 | + | 27260156 | TC71 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | -0.06415993602119519 | [776] | [791,762,778,856] | -2 | hSpCas9 | negative selection | 9300431 | 42831018 | 42831041 | 1 | + | 27260156 | TC32 | viability | GATCCTTGACGTGCGCCTTGAGG | ERMAP | ENSG00000164010 | 0.3014122455533842 | [234] | [215,207,373,326] | 5 | hSpCas9 | negative selection | 9421681 | 42831052 | 42831075 | 1 | + | 27260156 | TC32 | viability | TACCGATGTCTGATCCAAGTTGG | ERMAP | ENSG00000164010 | 0.23998517457410984 | [776] | [874,510,1064,1130] | 4 | hSpCas9 | negative selection | 9421682 | 42830778 | 42830801 | 1 | + | 27869803 | HPAFII | viability after 27 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.39315534645028344 | [152] | [43,156,NaN] | 3 | hSpCas9 | negative selection | 9534471 | 42831025 | 42831048 | 1 | + | 27869803 | HPAFII | viability after 27 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | 0.1916553903958862 | [419] | [207,288,NaN] | 1 | hSpCas9 | negative selection | 9534472 | 42830778 | 42830801 | 1 | + | 27869803 | HPAFII | viability after 15 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.005824920322804239 | [152] | [153,171,NaN] | 0 | hSpCas9 | negative selection | 9616920 | 42831025 | 42831048 | 1 | + | 27869803 | HPAFII | viability after 15 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.009028314985516372 | [419] | [664,313,NaN] | 0 | hSpCas9 | negative selection | 9616921 | 42830778 | 42830801 | 1 | + | 27869803 | ASPC1 | viability after 36 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.4325528213516375 | [490] | [324,325,87] | 4 | hSpCas9 | negative selection | 9699369 | 42831025 | 42831048 | 1 | + | 27869803 | ASPC1 | viability after 36 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | -0.4143548820027443 | [699] | [77,441,49] | -4 | hSpCas9 | negative selection | 9699370 | 42830778 | 42830801 | 1 | + | 27869803 | PATU8988S | viability after 35 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.03135215302756472 | [385] | [104,212,NaN] | 0 | hSpCas9 | negative selection | 9781818 | 42831025 | 42831048 | 1 | + | 27869803 | PATU8988S | viability after 35 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | 0.5204424819069793 | [586] | [168,509,NaN] | 6 | hSpCas9 | negative selection | 9781819 | 42830778 | 42830801 | 1 | + | 27869803 | PATU8988S | viability after 31 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.3119527259168867 | [385] | [132,264,NaN] | 4 | hSpCas9 | negative selection | 9864267 | 42831025 | 42831048 | 1 | + | 27869803 | PATU8988S | viability after 31 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | 0.34671643843055233 | [586] | [144,491,NaN] | 4 | hSpCas9 | negative selection | 9864268 | 42830778 | 42830801 | 1 | + | 27869803 | HPAFII | viability after 35 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.15235722825155706 | [152] | [15,164,NaN] | 0 | hSpCas9 | negative selection | 9946716 | 42831025 | 42831048 | 1 | + | 27869803 | HPAFII | viability after 35 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | 0.40751570926504277 | [419] | [210,361,NaN] | 2 | hSpCas9 | negative selection | 9946717 | 42830778 | 42830801 | 1 | + | 27869803 | HPAFII | viability after 31 days | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.19204121949775632 | [152] | [22,131,NaN] | -1 | hSpCas9 | negative selection | 10029165 | 42831025 | 42831048 | 1 | + | 27869803 | HPAFII | viability after 31 days | GACGTGCGCCTTGAGGACCAAGG | ERMAP | ENSG00000164010 | 0.3325771206757957 | [419] | [169,434,NaN] | 2 | hSpCas9 | negative selection | 10029166 | 42830852 | 42830875 | 1 | + | 28162770 | P31FUJ | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 0.1391665729725795 | [16] | [21] | 1 | hSpCas9 | negative selection | 10151201 | 42830980 | 42831003 | 1 | + | 28162770 | P31FUJ | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.24868524602103387 | [273] | [270] | -2 | hSpCas9 | negative selection | 10151202 | 42830908 | 42830931 | 1 | + | 28162770 | P31FUJ | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.11820312333740746 | [333] | [425] | 1 | hSpCas9 | negative selection | 10151203 | 42830951 | 42830974 | 1 | + | 28162770 | P31FUJ | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.15394678370313875 | [88] | [93] | -1 | hSpCas9 | negative selection | 10151204 | 42830490 | 42830513 | 1 | - | 28162770 | P31FUJ | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -3.009676520017221 | [280] | [40] | -9 | hSpCas9 | negative selection | 10151205 | 42830508 | 42830531 | 1 | - | 28162770 | P31FUJ | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.3976749555591461 | [311] | [482] | 4 | hSpCas9 | negative selection | 10151206 | 42830778 | 42830801 | 1 | + | 28162770 | P31FUJ | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.8569119169404755 | [677] | [1442] | 8 | hSpCas9 | negative selection | 10151207 | 42830790 | 42830813 | 1 | + | 28162770 | P31FUJ | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.25153517959222627 | [756] | [1058] | 2 | hSpCas9 | negative selection | 10151208 | 42830893 | 42830916 | 1 | - | 28162770 | P31FUJ | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.2232124390893932 | [268] | [368] | 2 | hSpCas9 | negative selection | 10151209 | 42830852 | 42830875 | 1 | + | 28162770 | TF1 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [1] | 1 | hSpCas9 | negative selection | 10320567 | 42830980 | 42831003 | 1 | + | 28162770 | TF1 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [253] | 1 | hSpCas9 | negative selection | 10320568 | 42830908 | 42830931 | 1 | + | 28162770 | TF1 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [274] | 1 | hSpCas9 | negative selection | 10320569 | 42830951 | 42830974 | 1 | + | 28162770 | TF1 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [92] | 1 | hSpCas9 | negative selection | 10320570 | 42830490 | 42830513 | 1 | - | 28162770 | TF1 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [65] | 1 | hSpCas9 | negative selection | 10320571 | 42830508 | 42830531 | 1 | - | 28162770 | TF1 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [229] | 1 | hSpCas9 | negative selection | 10320572 | 42830778 | 42830801 | 1 | + | 28162770 | TF1 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [336] | 1 | hSpCas9 | negative selection | 10320573 | 42830790 | 42830813 | 1 | + | 28162770 | TF1 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [505] | 1 | hSpCas9 | negative selection | 10320574 | 42830893 | 42830916 | 1 | - | 28162770 | TF1 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | NaN | [NaN] | [117] | 1 | hSpCas9 | negative selection | 10320575 | 42830852 | 42830875 | 1 | + | 28162770 | SKM1 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 1.7629608026991508 | [3] | [23] | 9 | hSpCas9 | negative selection | 10489933 | 42830980 | 42831003 | 1 | + | 28162770 | SKM1 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.19546009354944993 | [56] | [87] | -2 | hSpCas9 | negative selection | 10489934 | 42830908 | 42830931 | 1 | + | 28162770 | SKM1 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.00035538737484541727 | [81] | [144] | 0 | hSpCas9 | negative selection | 10489935 | 42830951 | 42830974 | 1 | + | 28162770 | SKM1 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.23703919730084944 | [21] | [32] | -2 | hSpCas9 | negative selection | 10489936 | 42830490 | 42830513 | 1 | - | 28162770 | SKM1 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -3.097008745521875 | [120] | [24] | -9 | hSpCas9 | negative selection | 10489937 | 42830508 | 42830531 | 1 | - | 28162770 | SKM1 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.4120536408400224 | [87] | [206] | 4 | hSpCas9 | negative selection | 10489938 | 42830778 | 42830801 | 1 | + | 28162770 | SKM1 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.40039072331444236 | [134] | [314] | 4 | hSpCas9 | negative selection | 10489939 | 42830790 | 42830813 | 1 | + | 28162770 | SKM1 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.09081373154361838 | [161] | [304] | 0 | hSpCas9 | negative selection | 10489940 | 42830893 | 42830916 | 1 | - | 28162770 | SKM1 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.7085130186767743 | [44] | [129] | 6 | hSpCas9 | negative selection | 10489941 | 42830852 | 42830875 | 1 | + | 28162770 | SKM1 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 1.7629608026991508 | [3] | [23] | 9 | hSpCas9 | negative selection | 10659299 | 42830980 | 42831003 | 1 | + | 28162770 | SKM1 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.19546009354944993 | [56] | [87] | -2 | hSpCas9 | negative selection | 10659300 | 42830908 | 42830931 | 1 | + | 28162770 | SKM1 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.00035538737484541727 | [81] | [144] | 0 | hSpCas9 | negative selection | 10659301 | 42830951 | 42830974 | 1 | + | 28162770 | SKM1 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.23703919730084944 | [21] | [32] | -2 | hSpCas9 | negative selection | 10659302 | 42830490 | 42830513 | 1 | - | 28162770 | SKM1 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -3.097008745521875 | [120] | [24] | -9 | hSpCas9 | negative selection | 10659303 | 42830508 | 42830531 | 1 | - | 28162770 | SKM1 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.4120536408400224 | [87] | [206] | 4 | hSpCas9 | negative selection | 10659304 | 42830778 | 42830801 | 1 | + | 28162770 | SKM1 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.40039072331444236 | [134] | [314] | 4 | hSpCas9 | negative selection | 10659305 | 42830790 | 42830813 | 1 | + | 28162770 | SKM1 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.09081373154361838 | [161] | [304] | 0 | hSpCas9 | negative selection | 10659306 | 42830893 | 42830916 | 1 | - | 28162770 | SKM1 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.7085130186767743 | [44] | [129] | 6 | hSpCas9 | negative selection | 10659307 | 42830852 | 42830875 | 1 | + | 28162770 | PL21 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -2.022252806847128 | [27] | [2] | -8 | hSpCas9 | negative selection | 10828665 | 42830980 | 42831003 | 1 | + | 28162770 | PL21 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.537835025234999 | [181] | [114] | 5 | hSpCas9 | negative selection | 10828666 | 42830908 | 42830931 | 1 | + | 28162770 | PL21 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | -0.5325765066755284 | [338] | [101] | -4 | hSpCas9 | negative selection | 10828667 | 42830951 | 42830974 | 1 | + | 28162770 | PL21 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.48338672071542554 | [105] | [32] | -3 | hSpCas9 | negative selection | 10828668 | 42830490 | 42830513 | 1 | - | 28162770 | PL21 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -0.4403179988235398 | [317] | [101] | -3 | hSpCas9 | negative selection | 10828669 | 42830508 | 42830531 | 1 | - | 28162770 | PL21 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | -0.013985190863527397 | [231] | [99] | 0 | hSpCas9 | negative selection | 10828670 | 42830778 | 42830801 | 1 | + | 28162770 | PL21 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.4854790996766657 | [459] | [142] | -3 | hSpCas9 | negative selection | 10828671 | 42830790 | 42830813 | 1 | + | 28162770 | PL21 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | -0.07659970663178672 | [549] | [226] | 0 | hSpCas9 | negative selection | 10828672 | 42830893 | 42830916 | 1 | - | 28162770 | PL21 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | -0.8850277687733572 | [156] | [36] | -6 | hSpCas9 | negative selection | 10828673 | 42830852 | 42830875 | 1 | + | 28162770 | P31FUJ | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 0.1391665729725795 | [16] | [21] | 1 | hSpCas9 | negative selection | 10998031 | 42830980 | 42831003 | 1 | + | 28162770 | P31FUJ | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.24868524602103387 | [273] | [270] | -2 | hSpCas9 | negative selection | 10998032 | 42830908 | 42830931 | 1 | + | 28162770 | P31FUJ | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.11820312333740746 | [333] | [425] | 1 | hSpCas9 | negative selection | 10998033 | 42830951 | 42830974 | 1 | + | 28162770 | P31FUJ | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.15394678370313875 | [88] | [93] | -1 | hSpCas9 | negative selection | 10998034 | 42830490 | 42830513 | 1 | - | 28162770 | P31FUJ | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -3.009676520017221 | [280] | [40] | -9 | hSpCas9 | negative selection | 10998035 | 42830508 | 42830531 | 1 | - | 28162770 | P31FUJ | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.3976749555591461 | [311] | [482] | 4 | hSpCas9 | negative selection | 10998036 | 42830778 | 42830801 | 1 | + | 28162770 | P31FUJ | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.8569119169404755 | [677] | [1442] | 8 | hSpCas9 | negative selection | 10998037 | 42830790 | 42830813 | 1 | + | 28162770 | P31FUJ | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.25153517959222627 | [756] | [1058] | 2 | hSpCas9 | negative selection | 10998038 | 42830893 | 42830916 | 1 | - | 28162770 | P31FUJ | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.2232124390893932 | [268] | [368] | 2 | hSpCas9 | negative selection | 10998039 | 42830852 | 42830875 | 1 | + | 28162770 | OCIAML5 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 1.1479334291360024 | [2] | [11] | 8 | hSpCas9 | negative selection | 11167397 | 42830980 | 42831003 | 1 | + | 28162770 | OCIAML5 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.15364708033039665 | [125] | [252] | 1 | hSpCas9 | negative selection | 11167398 | 42830908 | 42830931 | 1 | + | 28162770 | OCIAML5 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.007755771087742558 | [134] | [244] | 0 | hSpCas9 | negative selection | 11167399 | 42830951 | 42830974 | 1 | + | 28162770 | OCIAML5 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.55601816777308 | [51] | [137] | 5 | hSpCas9 | negative selection | 11167400 | 42830490 | 42830513 | 1 | - | 28162770 | OCIAML5 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -2.470976403508491 | [171] | [55] | -8 | hSpCas9 | negative selection | 11167401 | 42830508 | 42830531 | 1 | - | 28162770 | OCIAML5 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.9134681754989801 | [164] | [560] | 7 | hSpCas9 | negative selection | 11167402 | 42830778 | 42830801 | 1 | + | 28162770 | OCIAML5 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.4238573467276725 | [324] | [786] | 3 | hSpCas9 | negative selection | 11167403 | 42830790 | 42830813 | 1 | + | 28162770 | OCIAML5 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.2818309646535355 | [436] | [958] | 2 | hSpCas9 | negative selection | 11167404 | 42830893 | 42830916 | 1 | - | 28162770 | OCIAML5 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.11230951940528158 | [122] | [239] | 0 | hSpCas9 | negative selection | 11167405 | 42830852 | 42830875 | 1 | + | 28162770 | EOL1 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 0.5224493279991891 | [36] | [27] | 5 | hSpCas9 | negative selection | 11336763 | 42830980 | 42831003 | 1 | + | 28162770 | EOL1 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.3337642240208563 | [243] | [101] | -3 | hSpCas9 | negative selection | 11336764 | 42830908 | 42830931 | 1 | + | 28162770 | EOL1 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.20554126874263812 | [478] | [290] | 1 | hSpCas9 | negative selection | 11336765 | 42830951 | 42830974 | 1 | + | 28162770 | EOL1 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -1.314239088016582 | [117] | [24] | -7 | hSpCas9 | negative selection | 11336766 | 42830490 | 42830513 | 1 | - | 28162770 | EOL1 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -2.6106616939535217 | [683] | [58] | -9 | hSpCas9 | negative selection | 11336767 | 42830508 | 42830531 | 1 | - | 28162770 | EOL1 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.5353362596595959 | [405] | [309] | 5 | hSpCas9 | negative selection | 11336768 | 42830778 | 42830801 | 1 | + | 28162770 | EOL1 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.10668658298890299 | [757] | [429] | 1 | hSpCas9 | negative selection | 11336769 | 42830790 | 42830813 | 1 | + | 28162770 | EOL1 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.6606280051438185 | [651] | [542] | 6 | hSpCas9 | negative selection | 11336770 | 42830893 | 42830916 | 1 | - | 28162770 | EOL1 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.5402826210865074 | [200] | [153] | 5 | hSpCas9 | negative selection | 11336771 | 42830852 | 42830875 | 1 | + | 28162770 | MOLM13 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -2.910622241709151 | [51] | [4] | -8 | hSpCas9 | negative selection | 11506129 | 42830980 | 42831003 | 1 | + | 28162770 | MOLM13 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.4678893815445789 | [206] | [206] | 3 | hSpCas9 | negative selection | 11506130 | 42830908 | 42830931 | 1 | + | 28162770 | MOLM13 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 1.2762396089475505 | [413] | [724] | 8 | hSpCas9 | negative selection | 11506131 | 42830951 | 42830974 | 1 | + | 28162770 | MOLM13 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.9114960330201936 | [124] | [169] | 7 | hSpCas9 | negative selection | 11506132 | 42830490 | 42830513 | 1 | - | 28162770 | MOLM13 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -2.5898261163117082 | [407] | [48] | -8 | hSpCas9 | negative selection | 11506133 | 42830508 | 42830531 | 1 | - | 28162770 | MOLM13 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.39888659392414344 | [363] | [346] | 3 | hSpCas9 | negative selection | 11506134 | 42830778 | 42830801 | 1 | + | 28162770 | MOLM13 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.0665225383774144 | [658] | [454] | 0 | hSpCas9 | negative selection | 11506135 | 42830790 | 42830813 | 1 | + | 28162770 | MOLM13 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.07285490691335905 | [763] | [580] | 0 | hSpCas9 | negative selection | 11506136 | 42830893 | 42830916 | 1 | - | 28162770 | MOLM13 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | -0.5173136165273406 | [193] | [97] | -3 | hSpCas9 | negative selection | 11506137 | 42830852 | 42830875 | 1 | + | 28162770 | HEL | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | 1.5207483076217467 | [36] | [67] | 9 | hSpCas9 | negative selection | 11675495 | 42830980 | 42831003 | 1 | + | 28162770 | HEL | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.18419645902676332 | [203] | [114] | -1 | hSpCas9 | negative selection | 11675496 | 42830908 | 42830931 | 1 | + | 28162770 | HEL | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 1.1635709953017974 | [321] | [461] | 8 | hSpCas9 | negative selection | 11675497 | 42830951 | 42830974 | 1 | + | 28162770 | HEL | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.5671877989931801 | [97] | [92] | 5 | hSpCas9 | negative selection | 11675498 | 42830490 | 42830513 | 1 | - | 28162770 | HEL | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -2.688992437917364 | [442] | [43] | -8 | hSpCas9 | negative selection | 11675499 | 42830508 | 42830531 | 1 | - | 28162770 | HEL | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.2600190529942414 | [308] | [236] | 2 | hSpCas9 | negative selection | 11675500 | 42830778 | 42830801 | 1 | + | 28162770 | HEL | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.6667843059670078 | [475] | [483] | 6 | hSpCas9 | negative selection | 11675501 | 42830790 | 42830813 | 1 | + | 28162770 | HEL | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.21357100388662476 | [683] | [507] | 1 | hSpCas9 | negative selection | 11675502 | 42830893 | 42830916 | 1 | - | 28162770 | HEL | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | -0.1793794427289876 | [220] | [124] | -1 | hSpCas9 | negative selection | 11675503 | 42830852 | 42830875 | 1 | + | 28162770 | MV411 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -1.7800431856393317 | [52] | [12] | -8 | hSpCas9 | negative selection | 11844861 | 42830980 | 42831003 | 1 | + | 28162770 | MV411 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 1.0993389117936416 | [122] | [221] | 8 | hSpCas9 | negative selection | 11844862 | 42830908 | 42830931 | 1 | + | 28162770 | MV411 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.24743755078277524 | [233] | [233] | 2 | hSpCas9 | negative selection | 11844863 | 42830951 | 42830974 | 1 | + | 28162770 | MV411 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.9462680160622103 | [68] | [111] | 8 | hSpCas9 | negative selection | 11844864 | 42830490 | 42830513 | 1 | - | 28162770 | MV411 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -2.568305156767548 | [344] | [48] | -9 | hSpCas9 | negative selection | 11844865 | 42830508 | 42830531 | 1 | - | 28162770 | MV411 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.3615440364692968 | [242] | [262] | 3 | hSpCas9 | negative selection | 11844866 | 42830778 | 42830801 | 1 | + | 28162770 | MV411 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | -0.4910953385303911 | [613] | [367] | -4 | hSpCas9 | negative selection | 11844867 | 42830790 | 42830813 | 1 | + | 28162770 | MV411 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.4977609048670153 | [474] | [564] | 4 | hSpCas9 | negative selection | 11844868 | 42830893 | 42830916 | 1 | - | 28162770 | MV411 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | -0.17001854929871196 | [198] | [148] | -1 | hSpCas9 | negative selection | 11844869 | 42830852 | 42830875 | 1 | + | 28162770 | MONOMAC1 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -1.071505964975695 | [21] | [11] | -7 | hSpCas9 | negative selection | 12014227 | 42830980 | 42831003 | 1 | + | 28162770 | MONOMAC1 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.21515790245046493 | [126] | [168] | 2 | hSpCas9 | negative selection | 12014228 | 42830908 | 42830931 | 1 | + | 28162770 | MONOMAC1 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.4594789146866365 | [176] | [278] | 4 | hSpCas9 | negative selection | 12014229 | 42830951 | 42830974 | 1 | + | 28162770 | MONOMAC1 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.8167647659413865 | [62] | [40] | -6 | hSpCas9 | negative selection | 12014230 | 42830490 | 42830513 | 1 | - | 28162770 | MONOMAC1 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -1.9728216901162878 | [225] | [65] | -8 | hSpCas9 | negative selection | 12014231 | 42830508 | 42830531 | 1 | - | 28162770 | MONOMAC1 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | -0.49936038400740457 | [200] | [162] | -4 | hSpCas9 | negative selection | 12014232 | 42830778 | 42830801 | 1 | + | 28162770 | MONOMAC1 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.9995364007683754 | [297] | [682] | 8 | hSpCas9 | negative selection | 12014233 | 42830790 | 42830813 | 1 | + | 28162770 | MONOMAC1 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | -0.3099814330362989 | [331] | [306] | -3 | hSpCas9 | negative selection | 12014234 | 42830893 | 42830916 | 1 | - | 28162770 | MONOMAC1 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | -1.086478471911855 | [112] | [60] | -7 | hSpCas9 | negative selection | 12014235 | 42830852 | 42830875 | 1 | + | 28162770 | OCIAML2 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -0.2689959640725106 | [4] | [22] | -2 | hSpCas9 | negative selection | 12183593 | 42830980 | 42831003 | 1 | + | 28162770 | OCIAML2 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | 0.23265264266775623 | [38] | [253] | 2 | hSpCas9 | negative selection | 12183594 | 42830908 | 42830931 | 1 | + | 28162770 | OCIAML2 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.21561601131617658 | [54] | [353] | 2 | hSpCas9 | negative selection | 12183595 | 42830951 | 42830974 | 1 | + | 28162770 | OCIAML2 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | -0.49487737148883837 | [14] | [58] | -4 | hSpCas9 | negative selection | 12183596 | 42830490 | 42830513 | 1 | - | 28162770 | OCIAML2 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -1.6992542002901239 | [57] | [98] | -7 | hSpCas9 | negative selection | 12183597 | 42830508 | 42830531 | 1 | - | 28162770 | OCIAML2 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.9735886994486287 | [25] | [282] | 8 | hSpCas9 | negative selection | 12183598 | 42830778 | 42830801 | 1 | + | 28162770 | OCIAML2 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.0686994466731683 | [90] | [528] | 0 | hSpCas9 | negative selection | 12183599 | 42830790 | 42830813 | 1 | + | 28162770 | OCIAML2 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.23080933529490388 | [110] | [721] | 2 | hSpCas9 | negative selection | 12183600 | 42830893 | 42830916 | 1 | - | 28162770 | OCIAML2 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.9406457552404837 | [35] | [382] | 8 | hSpCas9 | negative selection | 12183601 | 42830852 | 42830875 | 1 | + | 28162770 | OCIAML3 | viability | GGACGGTACCCAAGGAGGTGAGG | ERMAP | ENSG00000164010 | -1.009045139603007 | [7] | [11] | -6 | hSpCas9 | negative selection | 12352959 | 42830980 | 42831003 | 1 | + | 28162770 | OCIAML3 | viability | CTAGTGAGAGATGCCCAAGAGGG | ERMAP | ENSG00000164010 | -0.5622987805968251 | [44] | [91] | -4 | hSpCas9 | negative selection | 12352960 | 42830908 | 42830931 | 1 | + | 28162770 | OCIAML3 | viability | GCTGTTCACATATTCCGGGATGG | ERMAP | ENSG00000164010 | 0.057044050854765604 | [63] | [200] | 0 | hSpCas9 | negative selection | 12352961 | 42830951 | 42830974 | 1 | + | 28162770 | OCIAML3 | viability | TGATGCCGGAATATAAGGGGAGG | ERMAP | ENSG00000164010 | 0.3128829552843553 | [23] | [89] | 3 | hSpCas9 | negative selection | 12352962 | 42830490 | 42830513 | 1 | - | 28162770 | OCIAML3 | viability | GGAGGAAGACGAGAGGGATGAGG | ERMAP | ENSG00000164010 | -1.4052459968689954 | [92] | [105] | -7 | hSpCas9 | negative selection | 12352963 | 42830508 | 42830531 | 1 | - | 28162770 | OCIAML3 | viability | ACACATGCACAGACAGCCGGAGG | ERMAP | ENSG00000164010 | 0.6120996974247952 | [69] | [322] | 5 | hSpCas9 | negative selection | 12352964 | 42830778 | 42830801 | 1 | + | 28162770 | OCIAML3 | viability | GGATGCCGGCAAGTTCCACGTGG | ERMAP | ENSG00000164010 | 0.16008213163325236 | [133] | [451] | 1 | hSpCas9 | negative selection | 12352965 | 42830790 | 42830813 | 1 | + | 28162770 | OCIAML3 | viability | GTTCCACGTGGCCCTACTAGGGG | ERMAP | ENSG00000164010 | 0.6393060673896307 | [140] | [662] | 6 | hSpCas9 | negative selection | 12352966 | 42830893 | 42830916 | 1 | - | 28162770 | OCIAML3 | viability | TGAACAGCCTGGGAGCGCTGCGG | ERMAP | ENSG00000164010 | 0.15601410666748933 | [43] | [147] | 1 | hSpCas9 | negative selection | 12352967 |