Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10595
• Symbol:ERN2
• Description:endoplasmic reticulum to nucleus signaling 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ERN2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
23692247	23692270	16	+	26472758	Jiyoye	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.6274415017339333	[96]	[112]	4	hSpCas9	negative selection	51653
23706377	23706400	16	+	26472758	Jiyoye	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	-0.754575688490739	[131]	[58]	-5	hSpCas9	negative selection	51654
23713319	23713342	16	-	26472758	Jiyoye	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.8507820329814879	[24]	[33]	6	hSpCas9	negative selection	51655
23713307	23713330	16	-	26472758	Jiyoye	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.0078621177729703	[11]	[8]	0	hSpCas9	negative selection	51656
23713271	23713294	16	-	26472758	Jiyoye	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-1.014781531712761	[208]	[77]	-6	hSpCas9	negative selection	51657
23707044	23707067	16	+	26472758	Jiyoye	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.23328223180698643	[105]	[67]	-2	hSpCas9	negative selection	51658
23706832	23706855	16	-	26472758	Jiyoye	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.3542804330737479	[249]	[240]	2	hSpCas9	negative selection	51659
23706790	23706813	16	-	26472758	Jiyoye	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.19190739460280692	[201]	[173]	1	hSpCas9	negative selection	51660
23706754	23706777	16	+	26472758	Jiyoye	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	-0.666197804824346	[241]	[114]	-5	hSpCas9	negative selection	51661
23706385	23706408	16	-	26472758	Jiyoye	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	0.4071753815058736	[16]	[16]	3	hSpCas9	negative selection	51662
23692247	23692270	16	+	26472758	KBM7	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	-0.6338121675432564	[539,378]	[204,76]	-5	hSpCas9	negative selection	242771
23706377	23706400	16	+	26472758	KBM7	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	-0.19673032999198203	[225,410]	[93,171]	-2	hSpCas9	negative selection	242772
23713319	23713342	16	-	26472758	KBM7	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-0.250567429853495	[183,165]	[75,62]	-2	hSpCas9	negative selection	242773
23713307	23713330	16	-	26472758	KBM7	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.8059137177898252	[13,18]	[3,4]	-6	hSpCas9	negative selection	242774
23713271	23713294	16	-	26472758	KBM7	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.6744697692172471	[933,585]	[318,130]	-5	hSpCas9	negative selection	242775
23707044	23707067	16	+	26472758	KBM7	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.741051204872271	[534,357]	[110,134]	-6	hSpCas9	negative selection	242776
23706832	23706855	16	-	26472758	KBM7	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	-0.10420382912492454	[1267,1283]	[556,564]	-1	hSpCas9	negative selection	242777
23706790	23706813	16	-	26472758	KBM7	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.2546326079030941	[645,660]	[249,474]	2	hSpCas9	negative selection	242778
23706754	23706777	16	+	26472758	KBM7	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.7314887565676229	[978,980]	[610,909]	7	hSpCas9	negative selection	242779
23706385	23706408	16	-	26472758	KBM7	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	1.1730800363603593	[57,76]	[73,71]	9	hSpCas9	negative selection	242780
23692247	23692270	16	+	26472758	Raji	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.27578106706931826	[209]	[58]	2	hSpCas9	negative selection	433889
23706377	23706400	16	+	26472758	Raji	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	-0.18807234815257168	[107]	[21]	-1	hSpCas9	negative selection	433890
23713319	23713342	16	-	26472758	Raji	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-1.1336245641301954	[103]	[10]	-7	hSpCas9	negative selection	433891
23713307	23713330	16	-	26472758	Raji	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	3.6923460360947553	[0]	[2]	9	hSpCas9	negative selection	433892
23713271	23713294	16	-	26472758	Raji	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-1.5308771915076058	[385]	[30]	-8	hSpCas9	negative selection	433893
23707044	23707067	16	+	26472758	Raji	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.29860882430223756	[158]	[29]	-3	hSpCas9	negative selection	433894
23706832	23706855	16	-	26472758	Raji	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	-0.6618508622649475	[858]	[125]	-5	hSpCas9	negative selection	433895
23706790	23706813	16	-	26472758	Raji	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	-0.22211777921856374	[381]	[75]	-2	hSpCas9	negative selection	433896
23706754	23706777	16	+	26472758	Raji	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	-0.2400796516209005	[569]	[111]	-2	hSpCas9	negative selection	433897
23706385	23706408	16	-	26472758	Raji	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	-0.47757896534755684	[89]	[14]	-4	hSpCas9	negative selection	433898
23692247	23692270	16	+	26472758	K562	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	-0.07349630471429205	[358]	[287]	0	hSpCas9	negative selection	625007
23706377	23706400	16	+	26472758	K562	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	-0.2468846658404643	[245]	[174]	-2	hSpCas9	negative selection	625008
23713319	23713342	16	-	26472758	K562	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.08018933188813748	[157]	[140]	0	hSpCas9	negative selection	625009
23713307	23713330	16	-	26472758	K562	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	0.6849913190524282	[13]	[18]	5	hSpCas9	negative selection	625010
23713271	23713294	16	-	26472758	K562	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-1.1286692236322606	[530]	[204]	-6	hSpCas9	negative selection	625011
23707044	23707067	16	+	26472758	K562	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.8153906675688566	[393]	[188]	-5	hSpCas9	negative selection	625012
23706832	23706855	16	-	26472758	K562	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.6826570703871564	[1171]	[1587]	5	hSpCas9	negative selection	625013
23706790	23706813	16	-	26472758	K562	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.374938761837981	[432]	[473]	3	hSpCas9	negative selection	625014
23706754	23706777	16	+	26472758	K562	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.42036751673652906	[716]	[809]	3	hSpCas9	negative selection	625015
23706385	23706408	16	-	26472758	K562	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	2.2444187276664467	[37]	[151]	9	hSpCas9	negative selection	625016
23704998	23705021	16	+	26627737	DLD1	viability	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.07998596415064618	[493]	[197,80,154]	-1	hSpCas9	negative selection	793256
23706372	23706395	16	+	26627737	DLD1	viability	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.0009766660733453447	[299]	[115,61,100]	0	hSpCas9	negative selection	793257
23706755	23706778	16	+	26627737	DLD1	viability	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.35066427832624814	[276]	[96,101,128]	3	hSpCas9	negative selection	793258
23710970	23710993	16	+	26627737	DLD1	viability	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.8126115985436342	[489]	[78,25,144]	-6	hSpCas9	negative selection	793259
23713174	23713197	16	+	26627737	DLD1	viability	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	1.0812828500858322	[190]	[119,171,93]	8	hSpCas9	negative selection	793260
23704998	23705021	16	+	26627737	GBM cells	viability after 5 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.9055166097099325	[108]	[104,113]	9	hSpCas9	negative selection	875571
23706372	23706395	16	+	26627737	GBM cells	viability after 5 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.4532880557734187	[142]	[116,92]	6	hSpCas9	negative selection	875572
23706755	23706778	16	+	26627737	GBM cells	viability after 5 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.606915986063371	[160]	[126,135]	8	hSpCas9	negative selection	875573
23710970	23710993	16	+	26627737	GBM cells	viability after 5 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	0.48088633300103023	[160]	[130,109]	7	hSpCas9	negative selection	875574
23713174	23713197	16	+	26627737	GBM cells	viability after 5 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.7563598449595126	[185]	[163,172]	8	hSpCas9	negative selection	875575
23704998	23705021	16	+	26627737	GBM cells	viability after 13 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.5005421145665754	[108]	[113,58]	6	hSpCas9	negative selection	957886
23706372	23706395	16	+	26627737	GBM cells	viability after 13 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.42326646146414104	[142]	[53,60]	-5	hSpCas9	negative selection	957887
23706755	23706778	16	+	26627737	GBM cells	viability after 13 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.9431879178657885	[160]	[162,171]	9	hSpCas9	negative selection	957888
23710970	23710993	16	+	26627737	GBM cells	viability after 13 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	0.5990318860255809	[160]	[219,60]	7	hSpCas9	negative selection	957889
23713174	23713197	16	+	26627737	GBM cells	viability after 13 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	1.107035329649854	[185]	[223,211]	9	hSpCas9	negative selection	957890
23704998	23705021	16	+	26627737	GBM cells	viability after 21 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.5513027115383992	[108]	[91,81]	5	hSpCas9	negative selection	1040201
23706372	23706395	16	+	26627737	GBM cells	viability after 21 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.280640256752108	[142]	[64,62]	-3	hSpCas9	negative selection	1040202
23706755	23706778	16	+	26627737	GBM cells	viability after 21 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.31691237145705226	[160]	[109,107]	3	hSpCas9	negative selection	1040203
23710970	23710993	16	+	26627737	GBM cells	viability after 21 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	0.4517920337086003	[160]	[139,100]	4	hSpCas9	negative selection	1040204
23713174	23713197	16	+	26627737	GBM cells	viability after 21 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.8711556379481807	[185]	[176,191]	8	hSpCas9	negative selection	1040205
23704998	23705021	16	+	26627737	RPE1	viability after 9 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.2330714453512419	[534]	[157,246]	1	hSpCas9	negative selection	1122516
23706372	23706395	16	+	26627737	RPE1	viability after 9 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.4258020714986727	[935]	[163,287]	-3	hSpCas9	negative selection	1122517
23706755	23706778	16	+	26627737	RPE1	viability after 9 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	1.302223270507913	[325]	[221,289]	7	hSpCas9	negative selection	1122518
23710970	23710993	16	+	26627737	RPE1	viability after 9 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	1.9631455227396413	[135]	[203,116]	8	hSpCas9	negative selection	1122519
23713174	23713197	16	+	26627737	RPE1	viability after 9 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.22328107814763343	[1029]	[375,376]	1	hSpCas9	negative selection	1122520
23704998	23705021	16	+	26627737	RPE1	viability after 12 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.2900385740432727	[534]	[98,256]	2	hSpCas9	negative selection	1204831
23706372	23706395	16	+	26627737	RPE1	viability after 12 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.37455295486718476	[935]	[141,248]	-3	hSpCas9	negative selection	1204832
23706755	23706778	16	+	26627737	RPE1	viability after 12 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.6883955669691337	[325]	[179,99]	4	hSpCas9	negative selection	1204833
23710970	23710993	16	+	26627737	RPE1	viability after 12 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	2.7882166705179854	[135]	[333,165]	9	hSpCas9	negative selection	1204834
23713174	23713197	16	+	26627737	RPE1	viability after 12 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.2604856766434944	[1029]	[381,277]	1	hSpCas9	negative selection	1204835
23704998	23705021	16	+	26627737	RPE1	viability after 15 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.3402878322558246	[534]	[60,175]	-2	hSpCas9	negative selection	1287146
23706372	23706395	16	+	26627737	RPE1	viability after 15 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.94542299361505	[935]	[137,136]	-5	hSpCas9	negative selection	1287147
23706755	23706778	16	+	26627737	RPE1	viability after 15 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	1.1559835363943713	[325]	[261,150]	6	hSpCas9	negative selection	1287148
23710970	23710993	16	+	26627737	RPE1	viability after 15 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	1.7889793525025306	[135]	[135,129]	8	hSpCas9	negative selection	1287149
23713174	23713197	16	+	26627737	RPE1	viability after 15 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.914238219678834	[1029]	[627,472]	5	hSpCas9	negative selection	1287150
23704998	23705021	16	+	26627737	RPE1	viability after 18 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.015099187107856071	[534]	[80,208]	0	hSpCas9	negative selection	1369461
23706372	23706395	16	+	26627737	RPE1	viability after 18 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.7014434707095464	[935]	[135,175]	-4	hSpCas9	negative selection	1369462
23706755	23706778	16	+	26627737	RPE1	viability after 18 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.6023272961414236	[325]	[149,115]	4	hSpCas9	negative selection	1369463
23710970	23710993	16	+	26627737	RPE1	viability after 18 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	1.7715407865382722	[135]	[177,68]	8	hSpCas9	negative selection	1369464
23713174	23713197	16	+	26627737	RPE1	viability after 18 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.4273660552125089	[1029]	[367,379]	2	hSpCas9	negative selection	1369465
23704998	23705021	16	+	26627737	HeLa	viability after 8 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.17913617964483158	[413]	[203,120,161]	-2	hSpCas9	negative selection	1451776
23706372	23706395	16	+	26627737	HeLa	viability after 8 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.7294045608214448	[271]	[300,58,247]	6	hSpCas9	negative selection	1451777
23706755	23706778	16	+	26627737	HeLa	viability after 8 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	1.0199935723177154	[240]	[353,189,130]	7	hSpCas9	negative selection	1451778
23710970	23710993	16	+	26627737	HeLa	viability after 8 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-1.2296179222411474	[466]	[104,101,58]	-8	hSpCas9	negative selection	1451779
23713174	23713197	16	+	26627737	HeLa	viability after 8 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.16594967352917156	[179]	[152,22,100]	1	hSpCas9	negative selection	1451780
23704998	23705021	16	+	26627737	HeLa	viability after 12 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-1.1469438629399362	[413]	[64,52,115]	-8	hSpCas9	negative selection	1534091
23706372	23706395	16	+	26627737	HeLa	viability after 12 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.6011951083510699	[271]	[221,104,192]	5	hSpCas9	negative selection	1534092
23706755	23706778	16	+	26627737	HeLa	viability after 12 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	1.301076446078546	[240]	[285,258,190]	8	hSpCas9	negative selection	1534093
23710970	23710993	16	+	26627737	HeLa	viability after 12 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-1.14476398401765	[466]	[16,160,73]	-8	hSpCas9	negative selection	1534094
23713174	23713197	16	+	26627737	HeLa	viability after 12 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	-0.10045698839765049	[179]	[141,52,16]	-1	hSpCas9	negative selection	1534095
23704998	23705021	16	+	26627737	HeLa	viability after 15 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.4121966598166617	[413]	[57,133,193]	-4	hSpCas9	negative selection	1616406
23706372	23706395	16	+	26627737	HeLa	viability after 15 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.04960021064714737	[271]	[26,93,232]	0	hSpCas9	negative selection	1616407
23706755	23706778	16	+	26627737	HeLa	viability after 15 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	1.385045876565063	[240]	[370,106,291]	8	hSpCas9	negative selection	1616408
23710970	23710993	16	+	26627737	HeLa	viability after 15 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.17768812400401102	[466]	[193,152,155]	-1	hSpCas9	negative selection	1616409
23713174	23713197	16	+	26627737	HeLa	viability after 15 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	1.336918914333274	[179]	[199,219,130]	8	hSpCas9	negative selection	1616410
23704998	23705021	16	+	26627737	HeLa	viability after 18 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.4068218802237663	[413]	[38,111,193]	-4	hSpCas9	negative selection	1698721
23706372	23706395	16	+	26627737	HeLa	viability after 18 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.06387288710665662	[271]	[20,76,232]	0	hSpCas9	negative selection	1698722
23706755	23706778	16	+	26627737	HeLa	viability after 18 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	1.4136806357035328	[240]	[256,90,291]	8	hSpCas9	negative selection	1698723
23710970	23710993	16	+	26627737	HeLa	viability after 18 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.11431592280680464	[466]	[142,128,155]	-1	hSpCas9	negative selection	1698724
23713174	23713197	16	+	26627737	HeLa	viability after 18 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	1.364201500388266	[179]	[133,190,130]	8	hSpCas9	negative selection	1698725
23704998	23705021	16	+	26627737	HCT116	viability after 6 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-3.3115982053205513	[615]	[21,2]	-9	hSpCas9	negative selection	1781036
23706372	23706395	16	+	26627737	HCT116	viability after 6 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	1.153632171731227	[803]	[43,411]	6	hSpCas9	negative selection	1781037
23706755	23706778	16	+	26627737	HCT116	viability after 6 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	-0.5435772708048973	[576]	[136,20]	-3	hSpCas9	negative selection	1781038
23710970	23710993	16	+	26627737	HCT116	viability after 6 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	0.626212554870614	[275]	[104,45]	3	hSpCas9	negative selection	1781039
23713174	23713197	16	+	26627737	HCT116	viability after 6 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.6796276822420985	[758]	[145,215]	4	hSpCas9	negative selection	1781040
23704998	23705021	16	+	26627737	HCT116	viability after 8 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.32425672066397393	[342]	[143,95,211]	-4	hSpCas9	negative selection	1863351
23706372	23706395	16	+	26627737	HCT116	viability after 8 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.0004476933084100465	[238]	[167,107,119]	0	hSpCas9	negative selection	1863352
23706755	23706778	16	+	26627737	HCT116	viability after 8 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.31093099066138397	[207]	[111,171,141]	3	hSpCas9	negative selection	1863353
23710970	23710993	16	+	26627737	HCT116	viability after 8 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	1.4196022602585927	[122]	[180,187,174]	9	hSpCas9	negative selection	1863354
23713174	23713197	16	+	26627737	HCT116	viability after 8 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.42342309450894866	[192]	[125,193,107]	4	hSpCas9	negative selection	1863355
23704998	23705021	16	+	26627737	HCT116	viability after 9 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-2.9431083760496324	[615]	[31,12]	-9	hSpCas9	negative selection	1945666
23706372	23706395	16	+	26627737	HCT116	viability after 9 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-1.201045250178789	[803]	[84,99]	-7	hSpCas9	negative selection	1945667
23706755	23706778	16	+	26627737	HCT116	viability after 9 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.23111506597510784	[576]	[148,205]	1	hSpCas9	negative selection	1945668
23710970	23710993	16	+	26627737	HCT116	viability after 9 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.06204882950721946	[275]	[21,108]	0	hSpCas9	negative selection	1945669
23713174	23713197	16	+	26627737	HCT116	viability after 9 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.7474946371918895	[758]	[561,164]	5	hSpCas9	negative selection	1945670
23704998	23705021	16	+	26627737	HCT116	viability after 12 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.5404931325033524	[342]	[94,109,168]	-5	hSpCas9	negative selection	2027981
23706372	23706395	16	+	26627737	HCT116	viability after 12 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.871825298219622	[238]	[55,67,82]	-7	hSpCas9	negative selection	2027982
23706755	23706778	16	+	26627737	HCT116	viability after 12 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.025139656547999212	[207]	[75,119,140]	0	hSpCas9	negative selection	2027983
23710970	23710993	16	+	26627737	HCT116	viability after 12 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	1.93610569808502	[122]	[420,130,171]	9	hSpCas9	negative selection	2027984
23713174	23713197	16	+	26627737	HCT116	viability after 12 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.5440985873826951	[192]	[161,129,149]	5	hSpCas9	negative selection	2027985
23704998	23705021	16	+	26627737	HCT116	viability after 15 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.4088868539272915	[342]	[116,151,171]	-4	hSpCas9	negative selection	2110296
23706372	23706395	16	+	26627737	HCT116	viability after 15 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.06756774408007599	[238]	[215,55,167]	0	hSpCas9	negative selection	2110297
23706755	23706778	16	+	26627737	HCT116	viability after 15 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.28841965578665174	[207]	[125,142,165]	3	hSpCas9	negative selection	2110298
23710970	23710993	16	+	26627737	HCT116	viability after 15 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	1.77654278400773	[122]	[443,179,127]	9	hSpCas9	negative selection	2110299
23713174	23713197	16	+	26627737	HCT116	viability after 15 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.7941357051146869	[192]	[150,179,239]	7	hSpCas9	negative selection	2110300
23704998	23705021	16	+	26627737	HCT116	viability after 18 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.06056636709237875	[342]	[56,123,304]	0	hSpCas9	negative selection	2192611
23706372	23706395	16	+	26627737	HCT116	viability after 18 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.4143130063624196	[238]	[228,19,224]	3	hSpCas9	negative selection	2192612
23706755	23706778	16	+	26627737	HCT116	viability after 18 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.1709186661887762	[207]	[109,76,156]	1	hSpCas9	negative selection	2192613
23710970	23710993	16	+	26627737	HCT116	viability after 18 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	1.3589556259818847	[122]	[324,60,73]	8	hSpCas9	negative selection	2192614
23713174	23713197	16	+	26627737	HCT116	viability after 18 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.6057111627403791	[192]	[103,122,202]	5	hSpCas9	negative selection	2192615
23713195	23713218	16	+	24336569	HL60	viability	GGGCAGCTGCACGGCTGGCCAGG	ERN2	ENSG00000134398	1.0474134181054402	[304]	[1333]	7	hSpCas9	negative selection	2263252
23713202	23713225	16	+	24336569	HL60	viability	TGCACGGCTGGCCAGGTCCCTGG	ERN2	ENSG00000134398	0.13459236392355214	[488]	[1135]	1	hSpCas9	negative selection	2263253
23713213	23713236	16	-	24336569	HL60	viability	CTTGGAGGCACCCAGGGACCTGG	ERN2	ENSG00000134398	0.3560074648088072	[1004]	[2721]	3	hSpCas9	negative selection	2263254
23713219	23713242	16	-	24336569	HL60	viability	CGCTCCCTTGGAGGCACCCAGGG	ERN2	ENSG00000134398	-0.17524091178549206	[1008]	[1890]	-1	hSpCas9	negative selection	2263255
23713228	23713251	16	-	24336569	HL60	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	0.24956958071137553	[536]	[1350]	2	hSpCas9	negative selection	2263256
23713249	23713272	16	-	24336569	HL60	viability	GAGCCTTCTCCGGGTCGGGCGGG	ERN2	ENSG00000134398	0.347734936073683	[810]	[2183]	3	hSpCas9	negative selection	2263257
23713254	23713277	16	-	24336569	HL60	viability	GGGCGGAGCCTTCTCCGGGTCGG	ERN2	ENSG00000134398	0.5077106513791747	[113]	[342]	4	hSpCas9	negative selection	2263258
23713294	23713317	16	-	24336569	HL60	viability	ATCGGCGAGGACTCCAGGCTGGG	ERN2	ENSG00000134398	-0.4360717173544168	[825]	[1291]	-4	hSpCas9	negative selection	2263259
23713318	23713341	16	-	24336569	HL60	viability	GGGAGTGTGATGAGAAGGGCGGG	ERN2	ENSG00000134398	-0.3786832083442052	[1041]	[1695]	-3	hSpCas9	negative selection	2263260
23713323	23713346	16	-	24336569	HL60	viability	CGGCTGGGAGTGTGATGAGAAGG	ERN2	ENSG00000134398	0.6978477842469045	[281]	[967]	6	hSpCas9	negative selection	2263261
23713195	23713218	16	+	24336569	KBM7	viability	GGGCAGCTGCACGGCTGGCCAGG	ERN2	ENSG00000134398	0.04021464516527545	[434]	[1219]	0	hSpCas9	negative selection	2330429
23713202	23713225	16	+	24336569	KBM7	viability	TGCACGGCTGGCCAGGTCCCTGG	ERN2	ENSG00000134398	0.9120635330843029	[369]	[1898]	7	hSpCas9	negative selection	2330430
23713213	23713236	16	-	24336569	KBM7	viability	CTTGGAGGCACCCAGGGACCTGG	ERN2	ENSG00000134398	-0.5563268598009071	[605]	[1123]	-4	hSpCas9	negative selection	2330431
23713219	23713242	16	-	24336569	KBM7	viability	CGCTCCCTTGGAGGCACCCAGGG	ERN2	ENSG00000134398	0.7915712225540215	[537]	[2539]	7	hSpCas9	negative selection	2330432
23713228	23713251	16	-	24336569	KBM7	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	-0.42789683068718287	[545]	[1106]	-4	hSpCas9	negative selection	2330433
23713249	23713272	16	-	24336569	KBM7	viability	GAGCCTTCTCCGGGTCGGGCGGG	ERN2	ENSG00000134398	0.09904369721260847	[482]	[1410]	0	hSpCas9	negative selection	2330434
23713254	23713277	16	-	24336569	KBM7	viability	GGGCGGAGCCTTCTCCGGGTCGG	ERN2	ENSG00000134398	0.27888073588897794	[316]	[1048]	2	hSpCas9	negative selection	2330435
23713294	23713317	16	-	24336569	KBM7	viability	ATCGGCGAGGACTCCAGGCTGGG	ERN2	ENSG00000134398	-0.0023707792866582422	[555]	[1513]	0	hSpCas9	negative selection	2330436
23713318	23713341	16	-	24336569	KBM7	viability	GGGAGTGTGATGAGAAGGGCGGG	ERN2	ENSG00000134398	0.864450437272242	[584]	[2904]	7	hSpCas9	negative selection	2330437
23713323	23713346	16	-	24336569	KBM7	viability	CGGCTGGGAGTGTGATGAGAAGG	ERN2	ENSG00000134398	-0.045094747613123154	[302]	[800]	0	hSpCas9	negative selection	2330438
23707667	23707690	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACTGCACTCCAGCCGAG	ERN2	ENSG00000134398	-0.41902599900673143	[34,218]	[4,37]	-2	dCas9-VP64	positive selection	2439545
23707667	23707690	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACTGCACTCCAGCCGAG	ERN2	ENSG00000134398	0.0771162345407751	[282,156]	[110,43]	0	dCas9-VP64	positive selection	2534800
23713202	23713225	16	+	27260157	DLD1	viability	TGCACGGCTGGCCAGGTCCCTGG	ERN2	ENSG00000134398	-0.800335373655499	[]	[]	-6	hSpCas9	negative selection	2574018
23713195	23713218	16	+	27260157	DLD1	viability	GGGCAGCTGCACGGCTGGCCAGG	ERN2	ENSG00000134398	1.23353035829007	[]	[]	9	hSpCas9	negative selection	2575001
23713213	23713236	16	-	27260157	DLD1	viability	CTTGGAGGCACCCAGGGACCTGG	ERN2	ENSG00000134398	-2.00503496928187	[]	[]	-8	hSpCas9	negative selection	2577910
23713174	23713197	16	+	27260157	DLD1	viability	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	-0.647096152104448	[]	[]	-5	hSpCas9	negative selection	2581968
23713219	23713242	16	-	27260157	DLD1	viability	CGCTCCCTTGGAGGCACCCAGGG	ERN2	ENSG00000134398	-0.797512769234322	[]	[]	-6	hSpCas9	negative selection	2582512
23713249	23713272	16	-	27260157	DLD1	viability	GAGCCTTCTCCGGGTCGGGCGGG	ERN2	ENSG00000134398	-1.26854822062117	[]	[]	-7	hSpCas9	negative selection	2607995
23706372	23706395	16	+	27260157	DLD1	viability	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.218070374925265	[]	[]	-2	hSpCas9	negative selection	2609245
23707039	23707062	16	+	27260157	DLD1	viability	GGAGAGGCATGAACCAGCTCAGG	ERN2	ENSG00000134398	-0.23365635972071	[]	[]	-2	hSpCas9	negative selection	2612631
23713254	23713277	16	-	27260157	DLD1	viability	GGGCGGAGCCTTCTCCGGGTCGG	ERN2	ENSG00000134398	-1.30669150627275	[]	[]	-7	hSpCas9	negative selection	2612963
23706751	23706774	16	+	27260157	DLD1	viability	CACGTGTTCGGCCAATGTAGAGG	ERN2	ENSG00000134398	-1.12830983943331	[]	[]	-7	hSpCas9	negative selection	2613114
23713112	23713135	16	+	27260157	DLD1	viability	CGAGCAGCAGCGCCGCGAACTGG	ERN2	ENSG00000134398	-0.180863642343854	[]	[]	-1	hSpCas9	negative selection	2614953
23713323	23713346	16	-	27260157	DLD1	viability	CGGCTGGGAGTGTGATGAGAAGG	ERN2	ENSG00000134398	-0.654796063424702	[]	[]	-5	hSpCas9	negative selection	2616192
23713294	23713317	16	-	27260157	DLD1	viability	ATCGGCGAGGACTCCAGGCTGGG	ERN2	ENSG00000134398	0.868759225903642	[]	[]	9	hSpCas9	negative selection	2617381
23705075	23705098	16	+	27260157	DLD1	viability	CACAGCACCGTCCCGCTTCCTGG	ERN2	ENSG00000134398	0.136018778356605	[]	[]	3	hSpCas9	negative selection	2619287
23705117	23705140	16	-	27260157	DLD1	viability	CACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	-0.311220544117425	[]	[]	-3	hSpCas9	negative selection	2621745
23713318	23713341	16	-	27260157	DLD1	viability	GGGAGTGTGATGAGAAGGGCGGG	ERN2	ENSG00000134398	-1.12442465089647	[]	[]	-7	hSpCas9	negative selection	2622481
23713167	23713190	16	-	27260157	DLD1	viability	CTATGGCGAGTGCGGTCAGGGGG	ERN2	ENSG00000134398	-2.6633748923018	[]	[]	-9	hSpCas9	negative selection	2623655
23710534	23710557	16	-	27260157	DLD1	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.30060812527137	[]	[]	9	hSpCas9	negative selection	2624032
23713228	23713251	16	-	27260157	DLD1	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	-1.04699154493952	[]	[]	-7	hSpCas9	negative selection	2624270
23710524	23710547	16	+	27260157	DLD1	viability	GTACATTGGTCCTTCGATGACGG	ERN2	ENSG00000134398	-0.728822020781627	[]	[]	-5	hSpCas9	negative selection	2648764
23713202	23713225	16	+	27260157	HT1080	viability	TGCACGGCTGGCCAGGTCCCTGG	ERN2	ENSG00000134398	0.619757085177987	[]	[]	5	hSpCas9	negative selection	2650148
23713195	23713218	16	+	27260157	HT1080	viability	GGGCAGCTGCACGGCTGGCCAGG	ERN2	ENSG00000134398	1.7138397851831	[]	[]	9	hSpCas9	negative selection	2651131
23713213	23713236	16	-	27260157	HT1080	viability	CTTGGAGGCACCCAGGGACCTGG	ERN2	ENSG00000134398	-1.63560940367514	[]	[]	-9	hSpCas9	negative selection	2654040
23713174	23713197	16	+	27260157	HT1080	viability	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.0633429688386967	[]	[]	0	hSpCas9	negative selection	2658098
23713219	23713242	16	-	27260157	HT1080	viability	CGCTCCCTTGGAGGCACCCAGGG	ERN2	ENSG00000134398	0.214750028848781	[]	[]	2	hSpCas9	negative selection	2658642
23713249	23713272	16	-	27260157	HT1080	viability	GAGCCTTCTCCGGGTCGGGCGGG	ERN2	ENSG00000134398	-1.11879906393261	[]	[]	-8	hSpCas9	negative selection	2684125
23706372	23706395	16	+	27260157	HT1080	viability	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.941547783561912	[]	[]	-8	hSpCas9	negative selection	2685375
23707039	23707062	16	+	27260157	HT1080	viability	GGAGAGGCATGAACCAGCTCAGG	ERN2	ENSG00000134398	1.51158567943334	[]	[]	9	hSpCas9	negative selection	2688761
23713254	23713277	16	-	27260157	HT1080	viability	GGGCGGAGCCTTCTCCGGGTCGG	ERN2	ENSG00000134398	0.0908840659968806	[]	[]	1	hSpCas9	negative selection	2689093
23706751	23706774	16	+	27260157	HT1080	viability	CACGTGTTCGGCCAATGTAGAGG	ERN2	ENSG00000134398	-0.78807221958274	[]	[]	-8	hSpCas9	negative selection	2689244
23713112	23713135	16	+	27260157	HT1080	viability	CGAGCAGCAGCGCCGCGAACTGG	ERN2	ENSG00000134398	-0.309281977810792	[]	[]	-7	hSpCas9	negative selection	2691083
23713323	23713346	16	-	27260157	HT1080	viability	CGGCTGGGAGTGTGATGAGAAGG	ERN2	ENSG00000134398	0.0611701363349376	[]	[]	0	hSpCas9	negative selection	2692322
23713294	23713317	16	-	27260157	HT1080	viability	ATCGGCGAGGACTCCAGGCTGGG	ERN2	ENSG00000134398	1.14930702157092	[]	[]	8	hSpCas9	negative selection	2693511
23705075	23705098	16	+	27260157	HT1080	viability	CACAGCACCGTCCCGCTTCCTGG	ERN2	ENSG00000134398	0.676515101501176	[]	[]	6	hSpCas9	negative selection	2695417
23705117	23705140	16	-	27260157	HT1080	viability	CACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	-0.215023739522737	[]	[]	0	hSpCas9	negative selection	2697875
23713318	23713341	16	-	27260157	HT1080	viability	GGGAGTGTGATGAGAAGGGCGGG	ERN2	ENSG00000134398	-0.0233113822377887	[]	[]	0	hSpCas9	negative selection	2698611
23713167	23713190	16	-	27260157	HT1080	viability	CTATGGCGAGTGCGGTCAGGGGG	ERN2	ENSG00000134398	-1.54341337394626	[]	[]	-9	hSpCas9	negative selection	2699785
23710534	23710557	16	-	27260157	HT1080	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.66788862020672	[]	[]	9	hSpCas9	negative selection	2700162
23713228	23713251	16	-	27260157	HT1080	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	-1.49616836548736	[]	[]	-9	hSpCas9	negative selection	2700400
23710524	23710547	16	+	27260157	HT1080	viability	GTACATTGGTCCTTCGATGACGG	ERN2	ENSG00000134398	0.113789175356554	[]	[]	1	hSpCas9	negative selection	2724894
23713202	23713225	16	+	27260157	MKN45	viability	TGCACGGCTGGCCAGGTCCCTGG	ERN2	ENSG00000134398	-0.851054185085747	[]	[]	-7	hSpCas9	negative selection	2726278
23713195	23713218	16	+	27260157	MKN45	viability	GGGCAGCTGCACGGCTGGCCAGG	ERN2	ENSG00000134398	1.12857088925445	[]	[]	8	hSpCas9	negative selection	2727261
23713213	23713236	16	-	27260157	MKN45	viability	CTTGGAGGCACCCAGGGACCTGG	ERN2	ENSG00000134398	-1.79864275512713	[]	[]	-9	hSpCas9	negative selection	2730170
23713174	23713197	16	+	27260157	MKN45	viability	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	-1.78710397047743	[]	[]	-9	hSpCas9	negative selection	2734228
23713219	23713242	16	-	27260157	MKN45	viability	CGCTCCCTTGGAGGCACCCAGGG	ERN2	ENSG00000134398	-0.995393816231909	[]	[]	-8	hSpCas9	negative selection	2734772
23713249	23713272	16	-	27260157	MKN45	viability	GAGCCTTCTCCGGGTCGGGCGGG	ERN2	ENSG00000134398	-0.276007156037981	[]	[]	-1	hSpCas9	negative selection	2760255
23706372	23706395	16	+	27260157	MKN45	viability	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.774269364685377	[]	[]	-7	hSpCas9	negative selection	2761505
23707039	23707062	16	+	27260157	MKN45	viability	GGAGAGGCATGAACCAGCTCAGG	ERN2	ENSG00000134398	-0.176339082454615	[]	[]	0	hSpCas9	negative selection	2764891
23713254	23713277	16	-	27260157	MKN45	viability	GGGCGGAGCCTTCTCCGGGTCGG	ERN2	ENSG00000134398	-0.900353169770878	[]	[]	-7	hSpCas9	negative selection	2765223
23706751	23706774	16	+	27260157	MKN45	viability	CACGTGTTCGGCCAATGTAGAGG	ERN2	ENSG00000134398	-1.10985052279305	[]	[]	-8	hSpCas9	negative selection	2765374
23713112	23713135	16	+	27260157	MKN45	viability	CGAGCAGCAGCGCCGCGAACTGG	ERN2	ENSG00000134398	-0.560103025155903	[]	[]	-6	hSpCas9	negative selection	2767213
23713323	23713346	16	-	27260157	MKN45	viability	CGGCTGGGAGTGTGATGAGAAGG	ERN2	ENSG00000134398	-2.29931695082855	[]	[]	-9	hSpCas9	negative selection	2768452
23713294	23713317	16	-	27260157	MKN45	viability	ATCGGCGAGGACTCCAGGCTGGG	ERN2	ENSG00000134398	0.680243893754614	[]	[]	7	hSpCas9	negative selection	2769641
23705075	23705098	16	+	27260157	MKN45	viability	CACAGCACCGTCCCGCTTCCTGG	ERN2	ENSG00000134398	0.066304045968774	[]	[]	0	hSpCas9	negative selection	2771547
23705117	23705140	16	-	27260157	MKN45	viability	CACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	-0.407515859399543	[]	[]	-1	hSpCas9	negative selection	2774005
23713318	23713341	16	-	27260157	MKN45	viability	GGGAGTGTGATGAGAAGGGCGGG	ERN2	ENSG00000134398	-0.935686345398401	[]	[]	-7	hSpCas9	negative selection	2774741
23713167	23713190	16	-	27260157	MKN45	viability	CTATGGCGAGTGCGGTCAGGGGG	ERN2	ENSG00000134398	-1.63422633397329	[]	[]	-9	hSpCas9	negative selection	2775915
23710534	23710557	16	-	27260157	MKN45	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.20018562331824	[]	[]	9	hSpCas9	negative selection	2776292
23713228	23713251	16	-	27260157	MKN45	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	-2.07917401687657	[]	[]	-9	hSpCas9	negative selection	2776530
23710524	23710547	16	+	27260157	MKN45	viability	GTACATTGGTCCTTCGATGACGG	ERN2	ENSG00000134398	0.47019800945442	[]	[]	6	hSpCas9	negative selection	2801024
23713202	23713225	16	+	27260157	RKO	viability	TGCACGGCTGGCCAGGTCCCTGG	ERN2	ENSG00000134398	0.686347199738389	[]	[]	7	hSpCas9	negative selection	2802408
23713195	23713218	16	+	27260157	RKO	viability	GGGCAGCTGCACGGCTGGCCAGG	ERN2	ENSG00000134398	1.14070008409018	[]	[]	9	hSpCas9	negative selection	2803391
23713213	23713236	16	-	27260157	RKO	viability	CTTGGAGGCACCCAGGGACCTGG	ERN2	ENSG00000134398	-2.3498812931564	[]	[]	-9	hSpCas9	negative selection	2806300
23713174	23713197	16	+	27260157	RKO	viability	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.725060950527953	[]	[]	8	hSpCas9	negative selection	2810358
23713219	23713242	16	-	27260157	RKO	viability	CGCTCCCTTGGAGGCACCCAGGG	ERN2	ENSG00000134398	-0.437690500579917	[]	[]	-6	hSpCas9	negative selection	2810902
23713249	23713272	16	-	27260157	RKO	viability	GAGCCTTCTCCGGGTCGGGCGGG	ERN2	ENSG00000134398	-0.00356231111636916	[]	[]	0	hSpCas9	negative selection	2836385
23706372	23706395	16	+	27260157	RKO	viability	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-1.00376331822518	[]	[]	-8	hSpCas9	negative selection	2837635
23707039	23707062	16	+	27260157	RKO	viability	GGAGAGGCATGAACCAGCTCAGG	ERN2	ENSG00000134398	0.760471224398083	[]	[]	8	hSpCas9	negative selection	2841021
23713254	23713277	16	-	27260157	RKO	viability	GGGCGGAGCCTTCTCCGGGTCGG	ERN2	ENSG00000134398	-0.679390121564565	[]	[]	-7	hSpCas9	negative selection	2841353
23706751	23706774	16	+	27260157	RKO	viability	CACGTGTTCGGCCAATGTAGAGG	ERN2	ENSG00000134398	-0.747102104280627	[]	[]	-7	hSpCas9	negative selection	2841504
23713112	23713135	16	+	27260157	RKO	viability	CGAGCAGCAGCGCCGCGAACTGG	ERN2	ENSG00000134398	-0.552787644502305	[]	[]	-7	hSpCas9	negative selection	2843343
23713323	23713346	16	-	27260157	RKO	viability	CGGCTGGGAGTGTGATGAGAAGG	ERN2	ENSG00000134398	-0.797088645228434	[]	[]	-7	hSpCas9	negative selection	2844582
23713294	23713317	16	-	27260157	RKO	viability	ATCGGCGAGGACTCCAGGCTGGG	ERN2	ENSG00000134398	1.2506179416853	[]	[]	9	hSpCas9	negative selection	2845771
23705075	23705098	16	+	27260157	RKO	viability	CACAGCACCGTCCCGCTTCCTGG	ERN2	ENSG00000134398	0.163182757708829	[]	[]	0	hSpCas9	negative selection	2847677
23705117	23705140	16	-	27260157	RKO	viability	CACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.0280459621311023	[]	[]	0	hSpCas9	negative selection	2850135
23713318	23713341	16	-	27260157	RKO	viability	GGGAGTGTGATGAGAAGGGCGGG	ERN2	ENSG00000134398	-0.136116533216775	[]	[]	0	hSpCas9	negative selection	2850871
23713167	23713190	16	-	27260157	RKO	viability	CTATGGCGAGTGCGGTCAGGGGG	ERN2	ENSG00000134398	-0.460927383733819	[]	[]	-6	hSpCas9	negative selection	2852045
23710534	23710557	16	-	27260157	RKO	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.59924338546712	[]	[]	9	hSpCas9	negative selection	2852422
23713228	23713251	16	-	27260157	RKO	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	-0.556638447681746	[]	[]	-7	hSpCas9	negative selection	2852660
23710524	23710547	16	+	27260157	RKO	viability	GTACATTGGTCCTTCGATGACGG	ERN2	ENSG00000134398	-0.0520833824711625	[]	[]	0	hSpCas9	negative selection	2877154
23713202	23713225	16	+	27260157	SF268	viability	TGCACGGCTGGCCAGGTCCCTGG	ERN2	ENSG00000134398	0.41817592225295	[]	[]	4	hSpCas9	negative selection	2878538
23713195	23713218	16	+	27260157	SF268	viability	GGGCAGCTGCACGGCTGGCCAGG	ERN2	ENSG00000134398	0.673011966698568	[]	[]	8	hSpCas9	negative selection	2879521
23713213	23713236	16	-	27260157	SF268	viability	CTTGGAGGCACCCAGGGACCTGG	ERN2	ENSG00000134398	-1.52222979669858	[]	[]	-8	hSpCas9	negative selection	2882430
23713174	23713197	16	+	27260157	SF268	viability	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	-0.21841102265492	[]	[]	-2	hSpCas9	negative selection	2886488
23713219	23713242	16	-	27260157	SF268	viability	CGCTCCCTTGGAGGCACCCAGGG	ERN2	ENSG00000134398	-0.361725304780759	[]	[]	-3	hSpCas9	negative selection	2887032
23713249	23713272	16	-	27260157	SF268	viability	GAGCCTTCTCCGGGTCGGGCGGG	ERN2	ENSG00000134398	-0.508990957667927	[]	[]	-4	hSpCas9	negative selection	2912515
23706372	23706395	16	+	27260157	SF268	viability	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-0.818935147546091	[]	[]	-6	hSpCas9	negative selection	2913765
23707039	23707062	16	+	27260157	SF268	viability	GGAGAGGCATGAACCAGCTCAGG	ERN2	ENSG00000134398	-0.348554311759346	[]	[]	-3	hSpCas9	negative selection	2917151
23713254	23713277	16	-	27260157	SF268	viability	GGGCGGAGCCTTCTCCGGGTCGG	ERN2	ENSG00000134398	0.150318906433785	[]	[]	0	hSpCas9	negative selection	2917483
23706751	23706774	16	+	27260157	SF268	viability	CACGTGTTCGGCCAATGTAGAGG	ERN2	ENSG00000134398	-0.911818321033864	[]	[]	-6	hSpCas9	negative selection	2917634
23713112	23713135	16	+	27260157	SF268	viability	CGAGCAGCAGCGCCGCGAACTGG	ERN2	ENSG00000134398	-0.389600667548448	[]	[]	-3	hSpCas9	negative selection	2919473
23713323	23713346	16	-	27260157	SF268	viability	CGGCTGGGAGTGTGATGAGAAGG	ERN2	ENSG00000134398	-1.0081634730297	[]	[]	-7	hSpCas9	negative selection	2920712
23713294	23713317	16	-	27260157	SF268	viability	ATCGGCGAGGACTCCAGGCTGGG	ERN2	ENSG00000134398	0.830213244241357	[]	[]	8	hSpCas9	negative selection	2921901
23705075	23705098	16	+	27260157	SF268	viability	CACAGCACCGTCCCGCTTCCTGG	ERN2	ENSG00000134398	0.0164578664257779	[]	[]	0	hSpCas9	negative selection	2923807
23705117	23705140	16	-	27260157	SF268	viability	CACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	-0.166885245300023	[]	[]	-1	hSpCas9	negative selection	2926265
23713318	23713341	16	-	27260157	SF268	viability	GGGAGTGTGATGAGAAGGGCGGG	ERN2	ENSG00000134398	-0.773488447086198	[]	[]	-6	hSpCas9	negative selection	2927001
23713167	23713190	16	-	27260157	SF268	viability	CTATGGCGAGTGCGGTCAGGGGG	ERN2	ENSG00000134398	-1.50989751594182	[]	[]	-8	hSpCas9	negative selection	2928175
23710534	23710557	16	-	27260157	SF268	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.988845237374162	[]	[]	9	hSpCas9	negative selection	2928552
23713228	23713251	16	-	27260157	SF268	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	-2.4085518389188	[]	[]	-9	hSpCas9	negative selection	2928790
23710524	23710547	16	+	27260157	SF268	viability	GTACATTGGTCCTTCGATGACGG	ERN2	ENSG00000134398	-0.0202801658695587	[]	[]	0	hSpCas9	negative selection	2953284
23706817	23706840	16	-	27013184	SW480	treatment with recombinant TRAIL	TGTGGTGGACCCTGAGTCAGGGG	ERN2	ENSG00000134398	-0.9010140506937577	[113,311]	[14,92]	-4	hSpCas9	positive selection	2960097
23706818	23706841	16	-	27013184	SW480	treatment with recombinant TRAIL	TTGTGGTGGACCCTGAGTCAGGG	ERN2	ENSG00000134398	1.6796825587199193	[237,394]	[599,182]	7	hSpCas9	positive selection	2960098
23706819	23706842	16	-	27013184	SW480	treatment with recombinant TRAIL	TTTGTGGTGGACCCTGAGTCAGG	ERN2	ENSG00000134398	2.979119524845848	[157,171]	[522,610]	9	hSpCas9	positive selection	2960099
23706835	23706858	16	-	27013184	SW480	treatment with recombinant TRAIL	GAAGCAGGATGCCTGGTTTGTGG	ERN2	ENSG00000134398	1.3483850052813988	[77,156]	[142,99]	6	hSpCas9	positive selection	2960100
23707006	23707029	16	-	27013184	SW480	treatment with recombinant TRAIL	TCTGATGGGGTCTTCTACACAGG	ERN2	ENSG00000134398	0.24590727325849904	[323,481]	[207,194]	1	hSpCas9	positive selection	2960101
23707052	23707075	16	-	27013184	SW480	treatment with recombinant TRAIL	GCCATTCACCATCCCTGAGCTGG	ERN2	ENSG00000134398	-0.7586633357441739	[1045,1371]	[295,316]	-3	hSpCas9	positive selection	2960102
23710956	23710979	16	+	27013184	SW480	treatment with recombinant TRAIL	TGCGTGGAGACTTCCATCCAAGG	ERN2	ENSG00000134398	-0.9084443372020671	[475,346]	[78,119]	-4	hSpCas9	positive selection	2960103
23710959	23710982	16	+	27013184	SW480	treatment with recombinant TRAIL	GTGGAGACTTCCATCCAAGGTGG	ERN2	ENSG00000134398	1.173462011088338	[82,362]	[225,174]	5	hSpCas9	positive selection	2960104
23711004	23711027	16	+	27013184	SW480	treatment with recombinant TRAIL	CCTGAGAGTATGAACCTGCAAGG	ERN2	ENSG00000134398	-2.141126504194444	[24,14]	[1,1]	-7	hSpCas9	positive selection	2960105
23711005	23711028	16	+	27013184	SW480	treatment with recombinant TRAIL	CTGAGAGTATGAACCTGCAAGGG	ERN2	ENSG00000134398	0.2144602451579416	[56,188]	[30,97]	1	hSpCas9	positive selection	2960106
23711006	23711029	16	+	27013184	SW480	treatment with recombinant TRAIL	TGAGAGTATGAACCTGCAAGGGG	ERN2	ENSG00000134398	3.6743591800616295	[1,7]	[42,1]	9	hSpCas9	positive selection	2960107
23711007	23711030	16	+	27013184	SW480	treatment with recombinant TRAIL	GAGAGTATGAACCTGCAAGGGGG	ERN2	ENSG00000134398	2.4099040463940313	[33,109]	[66,285]	8	hSpCas9	positive selection	2960108
23713174	23713197	16	+	27013184	SW480	treatment with recombinant TRAIL	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	1.8272899337216222	[153,137]	[189,273]	7	hSpCas9	positive selection	2960109
23713175	23713198	16	+	27013184	SW480	treatment with recombinant TRAIL	CCGCACTCGCCATAGCGCCTGGG	ERN2	ENSG00000134398	0.7424137695454441	[173,212]	[97,195]	3	hSpCas9	positive selection	2960110
23694708	23694731	16	+	27013184	SW480	treatment with recombinant TRAIL	GACTTGGTGGATAGACTCACAGG	ERN2	ENSG00000134398	-0.3734077013391708	[131,38]	[14,50]	-2	hSpCas9	positive selection	2960111
23713186	23713209	16	+	27013184	SW480	treatment with recombinant TRAIL	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	0.7853600031760247	[293,245]	[208,192]	4	hSpCas9	positive selection	2960112
23694717	23694740	16	+	27013184	SW480	treatment with recombinant TRAIL	GATAGACTCACAGGACTGTCTGG	ERN2	ENSG00000134398	1.4391261221900393	[55,24]	[74,11]	6	hSpCas9	positive selection	2960113
23694720	23694743	16	+	27013184	SW480	treatment with recombinant TRAIL	AGACTCACAGGACTGTCTGGTGG	ERN2	ENSG00000134398	1.6028054266680651	[98,145]	[104,232]	7	hSpCas9	positive selection	2960114
23713215	23713238	16	+	27013184	SW480	treatment with recombinant TRAIL	AGGTCCCTGGGTGCCTCCAAGGG	ERN2	ENSG00000134398	-0.9422780081789442	[448,734]	[113,152]	-4	hSpCas9	positive selection	2960115
23694724	23694747	16	+	27013184	SW480	treatment with recombinant TRAIL	TCACAGGACTGTCTGGTGGCAGG	ERN2	ENSG00000134398	1.1390219229084269	[213,142]	[177,164]	5	hSpCas9	positive selection	2960116
23713262	23713285	16	+	27013184	SW480	treatment with recombinant TRAIL	GAGAAGGCTCCGCCCCTGGCTGG	ERN2	ENSG00000134398	-0.34119910742952275	[200,162]	[69,51]	-1	hSpCas9	positive selection	2960117
23713263	23713286	16	+	27013184	SW480	treatment with recombinant TRAIL	AGAAGGCTCCGCCCCTGGCTGGG	ERN2	ENSG00000134398	0.7411412450657862	[245,362]	[134,330]	3	hSpCas9	positive selection	2960118
23710912	23710935	16	-	27013184	SW480	treatment with recombinant TRAIL	CTGAAGTGGACTCTGAGGGATGG	ERN2	ENSG00000134398	-4.755143015137734	[95,159]	[1,1]	-9	hSpCas9	positive selection	2960119
23710917	23710940	16	-	27013184	SW480	treatment with recombinant TRAIL	GGGACCTGAAGTGGACTCTGAGG	ERN2	ENSG00000134398	-0.19519006253589555	[107,66]	[24,45]	-1	hSpCas9	positive selection	2960120
23710985	23711008	16	-	27013184	SW480	treatment with recombinant TRAIL	CAGGCCAGAGAACCTCCTGCTGG	ERN2	ENSG00000134398	1.559974528729333	[183,273]	[289,280]	7	hSpCas9	positive selection	2960121
23711004	23711027	16	-	27013184	SW480	treatment with recombinant TRAIL	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.8320714754511919	[180,179]	[115,170]	4	hSpCas9	positive selection	2960122
23706807	23706830	16	+	27013184	SW480	treatment with recombinant TRAIL	ATCTGGGTCTCCCCTGACTCAGG	ERN2	ENSG00000134398	-0.13594234089869395	[115,181]	[25,101]	0	hSpCas9	positive selection	2960123
23706838	23706861	16	+	27013184	SW480	treatment with recombinant TRAIL	CAAACCAGGCATCCTGCTTCCGG	ERN2	ENSG00000134398	0.7255576502227508	[21,73]	[25,41]	3	hSpCas9	positive selection	2960124
23707044	23707067	16	+	27013184	SW480	treatment with recombinant TRAIL	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-1.5306303835031958	[1,26]	[1,1]	-6	hSpCas9	positive selection	2960125
23707080	23707103	16	+	27013184	SW480	treatment with recombinant TRAIL	CTAGGAGACGGAAAATTTACAGG	ERN2	ENSG00000134398	-2.0499402753189067	[17,37]	[1,3]	-7	hSpCas9	positive selection	2960126
23707014	23707037	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.46918301520619066	[3,2]	[2,0]	-6	hSpCas9	positive selection	2986351
23713187	23713210	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	-0.059603308269339836	[3,3]	[1,2]	-1	hSpCas9	positive selection	2986352
23713317	23713340	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTGTGATGAGAAGGGCGGGG	ERN2	ENSG00000134398	0.14418905291130824	[5,5]	[4,5]	3	hSpCas9	positive selection	2986353
23706374	23706397	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGGTGGTGTTCCAGCGCAGGG	ERN2	ENSG00000134398	-0.47664558616604985	[3,3]	[3,0]	-6	hSpCas9	positive selection	2986354
23707014	23707037	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.9638131244302234	[3,3]	[1,0]	-9	hSpCas9	positive selection	3054209
23713187	23713210	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	-0.6586037624527583	[3,3]	[1,0]	-8	hSpCas9	positive selection	3054210
23713317	23713340	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTGTGATGAGAAGGGCGGGG	ERN2	ENSG00000134398	0.0833726856845397	[5,5]	[4,3]	1	hSpCas9	positive selection	3054211
23706374	23706397	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGGTGGTGTTCCAGCGCAGGG	ERN2	ENSG00000134398	0.2956449364381125	[3,3]	[2,3]	5	hSpCas9	positive selection	3054212
23710510	23710533		+	24336571	A375	resistance to PLX after 7 days	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.31685356295255096	[16,12]	[11,11]	-8	hSpCas9	positive selection	3112501
23710939	23710962		-	24336571	A375	resistance to PLX after 7 days	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.6321898679187197	[4,4]	[2,2]	-9	hSpCas9	positive selection	3112502
23710534	23710557		-	24336571	A375	resistance to PLX after 7 days	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.19438761329461418	[6,6]	[6,8]	6	hSpCas9	positive selection	3112503
23710510	23710533		+	24336571	A375	resistance to PLX after 14 days	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.3580046383381181	[10,23]	[5,5]	-4	hSpCas9	positive selection	3170294
23710939	23710962		-	24336571	A375	resistance to PLX after 14 days	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.24348637087548175	[4,1]	[1,1]	2	hSpCas9	positive selection	3170295
23710534	23710557		-	24336571	A375	resistance to PLX after 14 days	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.29359980726079427	[9,5]	[1,2]	-3	hSpCas9	positive selection	3170296
23710510	23710533		+	24336571	A375	viability after 7 days	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.14302928409469465	[17]	[16,12]	-2	hSpCas9	negative selection	3228087
23710939	23710962		-	24336571	A375	viability after 7 days	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.6865634553139487	[8]	[4,4]	-7	hSpCas9	negative selection	3228088
23710534	23710557		-	24336571	A375	viability after 7 days	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.3159260727888372	[8]	[6,6]	-4	hSpCas9	negative selection	3228089
23710510	23710533		+	24336571	A375	viability after 14 days	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.0691775065427424	[17]	[10,23]	0	hSpCas9	negative selection	3285880
23710939	23710962		-	24336571	A375	viability after 14 days	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-1.1419916812528688	[8]	[4,1]	-9	hSpCas9	negative selection	3285881
23710534	23710557		-	24336571	A375	viability after 14 days	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.07934668312819204	[8]	[9,5]	-1	hSpCas9	negative selection	3285882
23710534	23710557	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.5660730577202817	[78,127]	[0,0]	3	hSpCas9	positive selection	3348337
23710510	23710533	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.05217243390000936	[228,246]	[0,1]	0	hSpCas9	positive selection	3348338
23710939	23710962	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.7493243470237305	[92,88]	[0,0]	3	hSpCas9	positive selection	3348339
23711004	23711027	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-1.1220521556254273	[332,332]	[0,0]	-7	hSpCas9	positive selection	3367544
23707013	23707036	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3367545
23710180	23710203	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	-0.14355322483634927	[168,168]	[0,0]	-1	hSpCas9	positive selection	3367546
23707013	23707036	16	+	26780180	HT29	viability (Avana library 4 designs)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.0117979583843627	[]	[]	0	hSpCas9	negative selection	3423178
23713186	23713209	16	+	26780180	HT29	viability (Avana library 4 designs)	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	0.47379341560692	[]	[]	1	hSpCas9	negative selection	3423179
23713317	23713340	16	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTGTGATGAGAAGGGCGGGG	ERN2	ENSG00000134398	0.525832040786973	[]	[]	2	hSpCas9	negative selection	3423180
23706373	23706396	16	+	26780180	HT29	viability (Avana library 4 designs)	GTAGGTGGTGTTCCAGCGCAGGG	ERN2	ENSG00000134398	0.593148699694641	[]	[]	2	hSpCas9	negative selection	3423181
23706373	23706396	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGTGGTGTTCCAGCGCAGGG	ERN2	ENSG00000134398	6.827415599635	[]	[]	9	hSpCas9	negative selection	3504202
23713186	23713209	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	4.02961964691868	[]	[]	6	hSpCas9	negative selection	3504203
23713317	23713340	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTGTGATGAGAAGGGCGGGG	ERN2	ENSG00000134398	5.06043161095568	[]	[]	8	hSpCas9	negative selection	3504204
23707013	23707036	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	2.96665739962168	[]	[]	4	hSpCas9	negative selection	3504205
23702609	23702632	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGACCACTTCTTACCACCAGGG	ERN2	ENSG00000134398	1.27453636415949	[]	[]	1	hSpCas9	negative selection	3504206
23710179	23710202	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGGGGACCCAAAAACAACAGGG	ERN2	ENSG00000134398	-2.19064345858342	[]	[]	-3	hSpCas9	negative selection	3504207
23706373	23706396	16	+	26780180	A375	viability (Avana lentiGuide)	GTAGGTGGTGTTCCAGCGCAGGG	ERN2	ENSG00000134398	5.66702070100152	[]	[]	5	hSpCas9	negative selection	3612861
23713186	23713209	16	+	26780180	A375	viability (Avana lentiGuide)	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	-4.50607200886786	[]	[]	-7	hSpCas9	negative selection	3612862
23713317	23713340	16	-	26780180	A375	viability (Avana lentiGuide)	GGAGTGTGATGAGAAGGGCGGGG	ERN2	ENSG00000134398	3.13170698548052	[]	[]	3	hSpCas9	negative selection	3612863
23707013	23707036	16	+	26780180	A375	viability (Avana lentiGuide)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	5.63360489647307	[]	[]	5	hSpCas9	negative selection	3612864
23702609	23702632	16	+	26780180	A375	viability (Avana lentiGuide)	GAGACCACTTCTTACCACCAGGG	ERN2	ENSG00000134398	-2.18057366324575	[]	[]	-4	hSpCas9	negative selection	3612865
23710179	23710202	16	-	26780180	A375	viability (Avana lentiGuide)	TTGGGGACCCAAAAACAACAGGG	ERN2	ENSG00000134398	3.31572532751253	[]	[]	3	hSpCas9	negative selection	3612866
23706373	23706396	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGTGGTGTTCCAGCGCAGGG	ERN2	ENSG00000134398	0.2562253311159537	[4]	[5,5]	7	hSpCas9	positive selection	3721520
23713186	23713209	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	0.1508729766294826	[5]	[5,5]	4	hSpCas9	positive selection	3721521
23713317	23713340	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTGTGATGAGAAGGGCGGGG	ERN2	ENSG00000134398	0.18653508540235153	[6]	[7,7]	5	hSpCas9	positive selection	3721522
23707013	23707036	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.025538992109796405	[4]	[5,3]	0	hSpCas9	positive selection	3721523
23702609	23702632	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGACCACTTCTTACCACCAGGG	ERN2	ENSG00000134398	0.12047572562402764	[4]	[5,4]	3	hSpCas9	positive selection	3721524
23710179	23710202	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGGGGACCCAAAAACAACAGGG	ERN2	ENSG00000134398	-0.7840606513160844	[4]	[2,2]	-8	hSpCas9	positive selection	3721525
23706373	23706396	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGTGGTGTTCCAGCGCAGGG	ERN2	ENSG00000134398	-0.033533996332674613	[5]	[3,4]	0	hSpCas9	positive selection	3830127
23713186	23713209	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCGCCTGGGCAGCTGCACGG	ERN2	ENSG00000134398	-0.37364724512080305	[5]	[4,1]	-5	hSpCas9	positive selection	3830128
23713317	23713340	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTGTGATGAGAAGGGCGGGG	ERN2	ENSG00000134398	0.0798787035688222	[7]	[6,6]	1	hSpCas9	positive selection	3830129
23707013	23707036	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.28490008938873507	[4]	[3,2]	-4	hSpCas9	positive selection	3830130
23702609	23702632	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGACCACTTCTTACCACCAGGG	ERN2	ENSG00000134398	0.2398676930955118	[5]	[5,5]	6	hSpCas9	positive selection	3830131
23710179	23710202	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGGGGACCCAAAAACAACAGGG	ERN2	ENSG00000134398	0.0613795469468313	[4]	[3,4]	1	hSpCas9	positive selection	3830132
23710510	23710533	16	+	26780180	A375	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	1.65156344840852	[]	[]	8	hSpCas9	negative selection	3937479
23707013	23707036	16	+	26780180	A375	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	1.23672732138146	[]	[]	6	hSpCas9	negative selection	3937480
23710939	23710962	16	-	26780180	A375	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	1.16261146024236	[]	[]	6	hSpCas9	negative selection	3937481
23710534	23710557	16	-	26780180	A375	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.2129422648855	[]	[]	6	hSpCas9	negative selection	3937482
23711004	23711027	16	-	26780180	A375	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	1.38422279680578	[]	[]	7	hSpCas9	negative selection	3937483
23710180	23710203	16	-	26780180	A375	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.478006457024909	[]	[]	1	hSpCas9	negative selection	3937484
23710510	23710533	16	+	26780180	HT29	viability (GeCKOv2 library)	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.895078103126534	[]	[]	4	hSpCas9	negative selection	4045445
23707013	23707036	16	+	26780180	HT29	viability (GeCKOv2 library)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	1.07245228713624	[]	[]	5	hSpCas9	negative selection	4045446
23710939	23710962	16	-	26780180	HT29	viability (GeCKOv2 library)	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	1.78165414072102	[]	[]	8	hSpCas9	negative selection	4045447
23710534	23710557	16	-	26780180	HT29	viability (GeCKOv2 library)	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.0491242938199	[]	[]	5	hSpCas9	negative selection	4045448
23711004	23711027	16	-	26780180	HT29	viability (GeCKOv2 library)	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.369311391711844	[]	[]	1	hSpCas9	negative selection	4045449
23710180	23710203	16	-	26780180	HT29	viability (GeCKOv2 library)	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	-0.102681991142288	[]	[]	-3	hSpCas9	negative selection	4045450
23710510	23710533	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.11860633680302325	[3]	[1,2]	-3	hSpCas9	positive selection	4135233
23710939	23710962	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.06359927285005895	[0]	[0,0]	1	hSpCas9	positive selection	4135234
23710534	23710557	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.172987723500158	[2]	[0,1]	-4	hSpCas9	positive selection	4135235
23710510	23710533	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	1.35331814949778	[2]	[0,3,2,4]	9	hSpCas9	positive selection	4199255
23710939	23710962	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.18998797949533275	[1]	[0,0,0,0]	-3	hSpCas9	positive selection	4199256
23710534	23710557	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.03346565492502661	[3]	[1,3,0,0]	0	hSpCas9	positive selection	4199257
23710534	23710557	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.16181983181331056	[2]	[1,1]	-3	hSpCas9	positive selection	4269204
23710510	23710533	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.2670466287386403	[3]	[3,3]	5	hSpCas9	positive selection	4269205
23710939	23710962	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.1314659627314854	[2]	[2,0]	-3	hSpCas9	positive selection	4269206
23711004	23711027	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.37459433266940556	[3]	[3,3]	7	hSpCas9	positive selection	4333469
23707013	23707036	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.1445892816304059	[2]	[2,0]	-3	hSpCas9	positive selection	4333470
23710180	23710203	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.599949176414617	[2]	[3,2]	9	hSpCas9	positive selection	4333471
23701097	23701119	16	+	27760321	OCIAML3	viability	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	-0.46596736232132013	[524,469]	[276,286]	-5	hSpCas9	negative selection	4398336
23705117	23705139	16	-	27760321	OCIAML3	viability	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.37867241575424404	[1232,966]	[913,1367]	4	hSpCas9	negative selection	4398337
23706755	23706777	16	+	27760321	OCIAML3	viability	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.36116889923266593	[517,481]	[399,635]	4	hSpCas9	negative selection	4398338
23710534	23710556	16	-	27760321	OCIAML3	viability	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.9574475096651647	[933,647]	[1176,1200]	9	hSpCas9	negative selection	4398339
23713170	23713192	16	-	27760321	OCIAML3	viability	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	0.02739037042382303	[533,528]	[344,528]	0	hSpCas9	negative selection	4398340
23701097	23701119	16	+	27760321	OCIAML2	viability	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	-0.40706278995248146	[524,469]	[303,301]	-5	hSpCas9	negative selection	4481799
23705117	23705139	16	-	27760321	OCIAML2	viability	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.4585655827370576	[1232,966]	[1070,1403]	6	hSpCas9	negative selection	4481800
23706755	23706777	16	+	27760321	OCIAML2	viability	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.3258156656715925	[517,481]	[466,559]	4	hSpCas9	negative selection	4481801
23710534	23710556	16	-	27760321	OCIAML2	viability	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.19275923094832748	[933,647]	[444,1088]	2	hSpCas9	negative selection	4481802
23713170	23713192	16	-	27760321	OCIAML2	viability	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.010303538672756352	[533,528]	[365,509]	0	hSpCas9	negative selection	4481803
23701097	23701119	16	+	27760321	MV411	viability	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	0.9592787909321046	[524,469]	[308,1130]	7	hSpCas9	negative selection	4565262
23705117	23705139	16	-	27760321	MV411	viability	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.986045314027131	[1232,966]	[1257,1683]	7	hSpCas9	negative selection	4565263
23706755	23706777	16	+	27760321	MV411	viability	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.744330556719131	[517,481]	[448,708]	5	hSpCas9	negative selection	4565264
23710534	23710556	16	-	27760321	MV411	viability	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.20916236547396327	[933,647]	[345,596]	-1	hSpCas9	negative selection	4565265
23713170	23713192	16	-	27760321	MV411	viability	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.358583612417083	[533,528]	[205,376]	-3	hSpCas9	negative selection	4565266
23701097	23701119	16	+	27760321	HL60	viability	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	0.14441288110763317	[524,469]	[551,338]	1	hSpCas9	negative selection	4648725
23705117	23705139	16	-	27760321	HL60	viability	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.7462904099327055	[1232,966]	[1606,1380]	8	hSpCas9	negative selection	4648726
23706755	23706777	16	+	27760321	HL60	viability	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.5289233201766417	[517,481]	[390,799]	6	hSpCas9	negative selection	4648727
23710534	23710556	16	-	27760321	HL60	viability	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.30350875399719635	[933,647]	[745,832]	4	hSpCas9	negative selection	4648728
23713170	23713192	16	-	27760321	HL60	viability	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	2.159560128285228	[533,528]	[2372,1491]	9	hSpCas9	negative selection	4648729
23701097	23701119	16	+	27760321	HT1080	viability	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	-0.8461034581060477	[469,366]	[118,63]	-4	hSpCas9	negative selection	4732188
23705117	23705139	16	-	27760321	HT1080	viability	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.6071378037700921	[966,754]	[795,222]	3	hSpCas9	negative selection	4732189
23706755	23706777	16	+	27760321	HT1080	viability	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.08412187298674262	[481,375]	[57,315]	0	hSpCas9	negative selection	4732190
23710534	23710556	16	-	27760321	HT1080	viability	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.7515204825014125	[647,505]	[407,363]	4	hSpCas9	negative selection	4732191
23713170	23713192	16	-	27760321	HT1080	viability	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	0.0446931329122327	[528,412]	[225,157]	0	hSpCas9	negative selection	4732192
23701097	23701119	16	+	27760321	HT29	viability after 7 days	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	-0.04522640443638448	[469,366]	[464,707,386]	0	hSpCas9	negative selection	4815651
23705117	23705139	16	-	27760321	HT29	viability after 7 days	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.6159451826583993	[966,754]	[1896,1907,1322]	8	hSpCas9	negative selection	4815652
23706755	23706777	16	+	27760321	HT29	viability after 7 days	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.41453996240530855	[481,375]	[577,487,1103]	6	hSpCas9	negative selection	4815653
23710534	23710556	16	-	27760321	HT29	viability after 7 days	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.4865120609551289	[647,505]	[1234,786,1119]	7	hSpCas9	negative selection	4815654
23713170	23713192	16	-	27760321	HT29	viability after 7 days	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.3032107541410495	[528,412]	[323,604,517]	-4	hSpCas9	negative selection	4815655
23701097	23701119	16	+	27760321	HT29	viability after 25 days	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	0.24612386498240255	[469,366]	[225,811,697]	2	hSpCas9	negative selection	4899114
23705117	23705139	16	-	27760321	HT29	viability after 25 days	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.6092864346222095	[966,754]	[1210,1662,1661]	7	hSpCas9	negative selection	4899115
23706755	23706777	16	+	27760321	HT29	viability after 25 days	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.30839781136794686	[481,375]	[587,665,562]	3	hSpCas9	negative selection	4899116
23710534	23710556	16	-	27760321	HT29	viability after 25 days	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.9594826953948258	[647,505]	[1008,1357,1519]	9	hSpCas9	negative selection	4899117
23713170	23713192	16	-	27760321	HT29	viability after 25 days	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.09066768872092673	[528,412]	[453,403,678]	-1	hSpCas9	negative selection	4899118
23701097	23701119	16	+	27760321	HT29	viability after 22 days	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	0.05685348562583195	[469,366]	[254,809,450]	0	hSpCas9	negative selection	4982577
23705117	23705139	16	-	27760321	HT29	viability after 22 days	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.7327230458656937	[966,754]	[1999,1390,1560]	8	hSpCas9	negative selection	4982578
23706755	23706777	16	+	27760321	HT29	viability after 22 days	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.42614968475311077	[481,375]	[688,686,621]	4	hSpCas9	negative selection	4982579
23710534	23710556	16	-	27760321	HT29	viability after 22 days	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.6746391014269811	[647,505]	[1042,1173,976]	7	hSpCas9	negative selection	4982580
23713170	23713192	16	-	27760321	HT29	viability after 22 days	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	0.21622902566010166	[528,412]	[398,657,848]	2	hSpCas9	negative selection	4982581
23701097	23701119	16	+	27760321	HT29	viability after 19 days	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	0.6725857219757538	[469,366]	[429,1022,798]	6	hSpCas9	negative selection	5066040
23705117	23705139	16	-	27760321	HT29	viability after 19 days	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.698578565853986	[966,754]	[1294,1826,1637]	7	hSpCas9	negative selection	5066041
23706755	23706777	16	+	27760321	HT29	viability after 19 days	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.40954486417859703	[481,375]	[773,557,635]	4	hSpCas9	negative selection	5066042
23710534	23710556	16	-	27760321	HT29	viability after 19 days	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.8767991852777076	[647,505]	[1597,1158,928]	8	hSpCas9	negative selection	5066043
23713170	23713192	16	-	27760321	HT29	viability after 19 days	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.0009288051825934174	[528,412]	[607,664,355]	0	hSpCas9	negative selection	5066044
23701097	23701119	16	+	27760321	HT29	viability after 16 days	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	0.0692204074926158	[469,366]	[364,710,379]	0	hSpCas9	negative selection	5149503
23705117	23705139	16	-	27760321	HT29	viability after 16 days	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.3999579499826693	[966,754]	[1314,1237,1264]	4	hSpCas9	negative selection	5149504
23706755	23706777	16	+	27760321	HT29	viability after 16 days	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.007642436118736107	[481,375]	[624,439,396]	0	hSpCas9	negative selection	5149505
23710534	23710556	16	-	27760321	HT29	viability after 16 days	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.092377464909935	[647,505]	[1746,1082,1341]	9	hSpCas9	negative selection	5149506
23713170	23713192	16	-	27760321	HT29	viability after 16 days	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.26909987880471586	[528,412]	[414,502,389]	-3	hSpCas9	negative selection	5149507
23701097	23701119	16	+	27760321	HT29	viability after 13 days	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	-0.13862540177490446	[469,366]	[369,593,363]	-2	hSpCas9	negative selection	5232966
23705117	23705139	16	-	27760321	HT29	viability after 13 days	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.48304315096876227	[966,754]	[1087,1724,1376]	6	hSpCas9	negative selection	5232967
23706755	23706777	16	+	27760321	HT29	viability after 13 days	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.0996523434369384	[481,375]	[665,478,458]	1	hSpCas9	negative selection	5232968
23710534	23710556	16	-	27760321	HT29	viability after 13 days	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.687066291753715	[647,505]	[1298,744,1181]	8	hSpCas9	negative selection	5232969
23713170	23713192	16	-	27760321	HT29	viability after 13 days	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.3016743660183764	[528,412]	[450,386,488]	-4	hSpCas9	negative selection	5232970
23701097	23701119	16	+	27760321	HT29	viability after 10 days	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	0.2821835001754851	[469,366]	[451,593,853]	4	hSpCas9	negative selection	5316429
23705117	23705139	16	-	27760321	HT29	viability after 10 days	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.33363243423836675	[966,754]	[1329,1305,1424]	4	hSpCas9	negative selection	5316430
23706755	23706777	16	+	27760321	HT29	viability after 10 days	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.17176278024143093	[481,375]	[769,650,394]	2	hSpCas9	negative selection	5316431
23710534	23710556	16	-	27760321	HT29	viability after 10 days	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.7976166188666242	[647,505]	[962,1548,1252]	9	hSpCas9	negative selection	5316432
23713170	23713192	16	-	27760321	HT29	viability after 10 days	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	-0.058851024322201295	[528,412]	[488,705,503]	-1	hSpCas9	negative selection	5316433
23701097	23701119	16	+	27760321	MOLM13	viability	TCGGCTCAGGCTCAATAGCTGG	ERN2	ENSG00000134398	1.2082116532395333	[524,469]	[859,466]	8	hSpCas9	negative selection	5399892
23705117	23705139	16	-	27760321	MOLM13	viability	ACCTGGCGTCCTGCGGGATGGG	ERN2	ENSG00000134398	0.49231954670545863	[1232,966]	[991,760]	3	hSpCas9	negative selection	5399893
23706755	23706777	16	+	27760321	MOLM13	viability	TGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	-0.4046716692359372	[517,481]	[183,237]	-3	hSpCas9	negative selection	5399894
23710534	23710556	16	-	27760321	MOLM13	viability	CTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.19265827964916915	[933,647]	[629,396]	1	hSpCas9	negative selection	5399895
23713170	23713192	16	-	27760321	MOLM13	viability	CGCTATGGCGAGTGCGGTCAGG	ERN2	ENSG00000134398	1.6630609979635655	[533,528]	[408,1414]	9	hSpCas9	negative selection	5399896
23712955	23712978	16	+	27661255	K562	viability	GGGCCGAGTTGGGACCACCCAGG	ERN2	ENSG00000134398	0.10815792845184047	[382,349]	[294,333]	4	dCas9-KRAB	negative selection	5477818
23712966	23712989	16	+	27661255	K562	viability	GGACCACCCAGGCGTGAGGGAGG	ERN2	ENSG00000134398	0.011457280061583475	[906,1006]	[848,700]	0	dCas9-KRAB	negative selection	5477819
23712868	23712891	16	-	27661255	K562	viability	GGAGATCTGCCAGCGTGGAAAGG	ERN2	ENSG00000134398	-0.07094575291747918	[1147,1254]	[969,862]	-3	dCas9-KRAB	negative selection	5477820
23713168	23713191	16	-	27661255	K562	viability	GCTATGGCGAGTGCGGTCAGGGG	ERN2	ENSG00000134398	0.09858046695168987	[730,718]	[636,605]	3	dCas9-KRAB	negative selection	5477821
23713184	23713207	16	-	27661255	K562	viability	GTGCAGCTGCCCAGGCGCTATGG	ERN2	ENSG00000134398	-0.10536224244403203	[488,458]	[360,344]	-4	dCas9-KRAB	negative selection	5477822
23713228	23713251	16	-	27661255	K562	viability	GGGACAGAGCGCTCCCTTGGAGG	ERN2	ENSG00000134398	-0.20669348492113712	[660,735]	[535,436]	-6	dCas9-KRAB	negative selection	5477823
23710534	23710557	16	-	27260156	BXPC3	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.6668877812646186	[264]	[437,516,400,388]	9	hSpCas9	negative selection	5541664
23710510	23710533	16	+	27260156	BXPC3	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.0339310249529412	[862]	[837,916,825,947]	0	hSpCas9	negative selection	5541665
23710939	23710962	16	-	27260156	BXPC3	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.1481067765139874	[321]	[315,245,317,339]	-3	hSpCas9	negative selection	5541666
23711004	23711027	16	-	27260156	BXPC3	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.10052385476182546	[738]	[675,684,804,719]	-2	hSpCas9	negative selection	5605929
23707013	23707036	16	+	27260156	BXPC3	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.3782776562159818	[255]	[589,282,196,285]	7	hSpCas9	negative selection	5605930
23710180	23710203	16	-	27260156	BXPC3	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.7277233122577895	[262]	[428,401,488,511]	9	hSpCas9	negative selection	5605931
23710534	23710557	16	-	27260156	A673	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.2781478428136873	[264]	[385,327,423,406]	6	hSpCas9	negative selection	5662915
23710510	23710533	16	+	27260156	A673	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.18410963790367563	[862]	[898,1025,819,896]	-4	hSpCas9	negative selection	5662916
23710939	23710962	16	-	27260156	A673	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.18577954918252548	[321]	[366,348,381,258]	-4	hSpCas9	negative selection	5662917
23711004	23711027	16	-	27260156	A673	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.09264287747739075	[738]	[836,763,715,1023]	-2	hSpCas9	negative selection	5727180
23707013	23707036	16	+	27260156	A673	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.0020027934315720586	[255]	[392,250,291,305]	0	hSpCas9	negative selection	5727181
23710180	23710203	16	-	27260156	A673	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.845389760984158	[262]	[627,536,506,606]	9	hSpCas9	negative selection	5727182
23710534	23710557	16	-	27260156	A375	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.4777990268403126	[264]	[347,380,527,454]	7	hSpCas9	negative selection	5784166
23710510	23710533	16	+	27260156	A375	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.05328833764768126	[862]	[1171,1222,855,963]	0	hSpCas9	negative selection	5784167
23710939	23710962	16	-	27260156	A375	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.04221748815036086	[321]	[427,326,429,357]	0	hSpCas9	negative selection	5784168
23711004	23711027	16	-	27260156	A375	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.18168839555717953	[738]	[998,1148,1049,763]	2	hSpCas9	negative selection	5848431
23707013	23707036	16	+	27260156	A375	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.530522994271763	[255]	[173,285,152,222]	-6	hSpCas9	negative selection	5848432
23710180	23710203	16	-	27260156	A375	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	1.0524986828611662	[262]	[584,672,741,559]	9	hSpCas9	negative selection	5848433
23710534	23710557	16	-	27260156	COLO741	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.5536204632557311	[264]	[325,726,427]	9	hSpCas9	negative selection	5905417
23710510	23710533	16	+	27260156	COLO741	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.13238099891510258	[862]	[981,1182,859]	-3	hSpCas9	negative selection	5905418
23710939	23710962	16	-	27260156	COLO741	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.20682025758854983	[321]	[354,363,349]	-4	hSpCas9	negative selection	5905419
23711004	23711027	16	-	27260156	COLO741	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.10466870781494009	[738]	[1237,1045,794]	2	hSpCas9	negative selection	5969682
23707013	23707036	16	+	27260156	COLO741	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.11024092739069813	[255]	[302,240,359]	-2	hSpCas9	negative selection	5969683
23710180	23710203	16	-	27260156	COLO741	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.5347026863459639	[262]	[528,435,496]	9	hSpCas9	negative selection	5969684
23710534	23710557	16	-	27260156	CAL120	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.11030000116439487	[264]	[313,374,229]	-2	hSpCas9	negative selection	6026668
23710510	23710533	16	+	27260156	CAL120	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.18950921480847505	[862]	[1315,619,944]	-3	hSpCas9	negative selection	6026669
23710939	23710962	16	-	27260156	CAL120	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.5952278504179438	[321]	[268,252,273]	-7	hSpCas9	negative selection	6026670
23711004	23711027	16	-	27260156	CAL120	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.47055869913734094	[738]	[1740,1076,1077]	7	hSpCas9	negative selection	6090933
23707013	23707036	16	+	27260156	CAL120	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.2988842171572098	[255]	[151,144,459]	-4	hSpCas9	negative selection	6090934
23710180	23710203	16	-	27260156	CAL120	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.378401411827117	[262]	[413,413,445]	5	hSpCas9	negative selection	6090935
23710534	23710557	16	-	27260156	CADOES1	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.22504356215421395	[264]	[281,279,232,359]	4	hSpCas9	negative selection	6147919
23710510	23710533	16	+	27260156	CADOES1	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.03503112470737346	[862]	[928,934,589,835]	0	hSpCas9	negative selection	6147920
23710939	23710962	16	-	27260156	CADOES1	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.029803664249163253	[321]	[464,291,172,291]	0	hSpCas9	negative selection	6147921
23711004	23711027	16	-	27260156	CADOES1	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.07440363251340454	[738]	[633,612,736,625]	-1	hSpCas9	negative selection	6212184
23707013	23707036	16	+	27260156	CADOES1	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.3871701599656091	[255]	[215,213,146,149]	-6	hSpCas9	negative selection	6212185
23710180	23710203	16	-	27260156	CADOES1	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.7994916908421521	[262]	[422,531,377,367]	9	hSpCas9	negative selection	6212186
23710534	23710557	16	-	27260156	EWS502	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.606673346109168	[264]	[509,399,394,390]	9	hSpCas9	negative selection	6269170
23710510	23710533	16	+	27260156	EWS502	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.1391901411602281	[862]	[597,793,1008,956]	-3	hSpCas9	negative selection	6269171
23710939	23710962	16	-	27260156	EWS502	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.2869642292161593	[321]	[237,352,274,250]	-5	hSpCas9	negative selection	6269172
23711004	23711027	16	-	27260156	EWS502	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.2372453940098197	[738]	[855,889,753,1214]	4	hSpCas9	negative selection	6333435
23707013	23707036	16	+	27260156	EWS502	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.322563535939114	[255]	[183,149,269,273]	-5	hSpCas9	negative selection	6333436
23710180	23710203	16	-	27260156	EWS502	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.8658841975087941	[262]	[300,722,546,471]	9	hSpCas9	negative selection	6333437
23710534	23710557	16	-	27260156	EW8	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.13986213996542152	[264]	[212,313,186,237]	2	hSpCas9	negative selection	6390421
23710510	23710533	16	+	27260156	EW8	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.21016318951670165	[862]	[788,608,360,718]	-4	hSpCas9	negative selection	6390422
23710939	23710962	16	-	27260156	EW8	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.34438849041269903	[321]	[208,222,193,197]	-6	hSpCas9	negative selection	6390423
23711004	23711027	16	-	27260156	EW8	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.12526380502294943	[738]	[677,506,536,488]	-2	hSpCas9	negative selection	6454686
23707013	23707036	16	+	27260156	EW8	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.74172176718547	[255]	[126,111,154,96]	-8	hSpCas9	negative selection	6454687
23710180	23710203	16	-	27260156	EW8	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.7806729687232306	[262]	[377,353,352,381]	9	hSpCas9	negative selection	6454688
23710534	23710557	16	-	27260156	CORL105	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.19195085387633481	[264]	[347,263,400,412]	3	hSpCas9	negative selection	6511672
23710510	23710533	16	+	27260156	CORL105	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.02995549852661694	[862]	[1010,1010,1068,879]	0	hSpCas9	negative selection	6511673
23710939	23710962	16	-	27260156	CORL105	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.05331177433658485	[321]	[425,342,418,382]	1	hSpCas9	negative selection	6511674
23711004	23711027	16	-	27260156	CORL105	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.09054843981598804	[738]	[800,659,920,886]	-2	hSpCas9	negative selection	6575937
23707013	23707036	16	+	27260156	CORL105	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.23353362320380422	[255]	[437,209,221,151]	-4	hSpCas9	negative selection	6575938
23710180	23710203	16	-	27260156	CORL105	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.5191924495033278	[262]	[335,474,601,372]	8	hSpCas9	negative selection	6575939
23710534	23710557	16	-	27260156	HS294T	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	1.2004605683138985	[264]	[364,260,123,165]	9	hSpCas9	negative selection	6632923
23710510	23710533	16	+	27260156	HS294T	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.05473783288859091	[862]	[247,351,340,474]	0	hSpCas9	negative selection	6632924
23710939	23710962	16	-	27260156	HS294T	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.2867238773157919	[321]	[67,287,84,172]	4	hSpCas9	negative selection	6632925
23711004	23711027	16	-	27260156	HS294T	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.021913498828786127	[738]	[229,214,420,262]	0	hSpCas9	negative selection	6697188
23707013	23707036	16	+	27260156	HS294T	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.21173638058257216	[255]	[81,61,71,134]	-3	hSpCas9	negative selection	6697189
23710180	23710203	16	-	27260156	HS294T	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.30480925474739307	[262]	[134,120,105,141]	4	hSpCas9	negative selection	6697190
23710534	23710557	16	-	27260156	HCC44	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.04421741793608347	[264]	[351,276,402,228]	0	hSpCas9	negative selection	6754174
23710510	23710533	16	+	27260156	HCC44	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.034061881020852725	[862]	[1048,836,915,1193]	0	hSpCas9	negative selection	6754175
23710939	23710962	16	-	27260156	HCC44	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.08521230666944424	[321]	[334,200,661,249]	-1	hSpCas9	negative selection	6754176
23711004	23711027	16	-	27260156	HCC44	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.20531959142260003	[738]	[1122,628,1156,1030]	3	hSpCas9	negative selection	6818439
23707013	23707036	16	+	27260156	HCC44	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.06608302640234298	[255]	[354,306,299,152]	-1	hSpCas9	negative selection	6818440
23710180	23710203	16	-	27260156	HCC44	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.6810975649304167	[262]	[472,293,703,496]	9	hSpCas9	negative selection	6818441
23710534	23710557	16	-	27260156	G402	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.29638940989682083	[264]	[503,174,312,97]	-4	hSpCas9	negative selection	6875425
23710510	23710533	16	+	27260156	G402	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.006930935404387384	[862]	[931,916,1615,714]	0	hSpCas9	negative selection	6875426
23710939	23710962	16	-	27260156	G402	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.1428970860553367	[321]	[340,359,286,713]	1	hSpCas9	negative selection	6875427
23711004	23711027	16	-	27260156	G402	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.5985733113427887	[738]	[2157,1580,1149,725]	7	hSpCas9	negative selection	6939690
23707013	23707036	16	+	27260156	G402	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.20732106103359815	[255]	[300,360,76,347]	-3	hSpCas9	negative selection	6939691
23710180	23710203	16	-	27260156	G402	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.956206008361593	[262]	[751,716,350,688]	9	hSpCas9	negative selection	6939692
23710534	23710557	16	-	27260156	L33	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.37046837059422016	[264]	[339,154,204,325]	7	hSpCas9	negative selection	6996676
23710510	23710533	16	+	27260156	L33	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.07381405995163315	[862]	[680,370,628,697]	-2	hSpCas9	negative selection	6996677
23710939	23710962	16	-	27260156	L33	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.1804468694542818	[321]	[353,90,171,284]	-4	hSpCas9	negative selection	6996678
23711004	23711027	16	-	27260156	L33	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.06487553657605183	[738]	[657,289,414,799]	-1	hSpCas9	negative selection	7060941
23707013	23707036	16	+	27260156	L33	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.6629930151567126	[255]	[54,43,198,170]	-9	hSpCas9	negative selection	7060942
23710180	23710203	16	-	27260156	L33	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.6231377479265725	[262]	[381,148,245,482]	9	hSpCas9	negative selection	7060943
23710534	23710557	16	-	27260156	K562	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.302978652426653	[264]	[606,282,128,178]	4	hSpCas9	negative selection	7117927
23710510	23710533	16	+	27260156	K562	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.03167004317151245	[862]	[737,753,971,671]	0	hSpCas9	negative selection	7117928
23710939	23710962	16	-	27260156	K562	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.45195785554737444	[321]	[507,478,357,247]	6	hSpCas9	negative selection	7117929
23711004	23711027	16	-	27260156	K562	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.054635566888639686	[738]	[622,1015,485,616]	0	hSpCas9	negative selection	7182192
23707013	23707036	16	+	27260156	K562	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.46096974971989557	[255]	[193,69,247,146]	-5	hSpCas9	negative selection	7182193
23710180	23710203	16	-	27260156	K562	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	1.1952671768399203	[262]	[306,1103,344,405]	9	hSpCas9	negative selection	7182194
23710534	23710557	16	-	27260156	HT29	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.44249239683250047	[264]	[517,404,513,327]	8	hSpCas9	negative selection	7239178
23710510	23710533	16	+	27260156	HT29	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.14394013267906636	[862]	[1216,1457,983,1016]	2	hSpCas9	negative selection	7239179
23710939	23710962	16	-	27260156	HT29	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.38171764665178365	[321]	[412,221,279,287]	-6	hSpCas9	negative selection	7239180
23711004	23711027	16	-	27260156	HT29	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.3236648451960453	[738]	[1295,1230,1135,878]	6	hSpCas9	negative selection	7303443
23707013	23707036	16	+	27260156	HT29	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.020762944730911892	[255]	[398,193,284,339]	0	hSpCas9	negative selection	7303444
23710180	23710203	16	-	27260156	HT29	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.994610348382877	[262]	[858,390,585,695]	9	hSpCas9	negative selection	7303445
23710534	23710557	16	-	27260156	MHHES1	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.27127226216698996	[264]	[228,387,508,306]	5	hSpCas9	negative selection	7360429
23710510	23710533	16	+	27260156	MHHES1	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.2865826244082146	[862]	[584,1026,654,878]	-5	hSpCas9	negative selection	7360430
23710939	23710962	16	-	27260156	MHHES1	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.16870579017898968	[321]	[401,357,245,295]	-3	hSpCas9	negative selection	7360431
23711004	23711027	16	-	27260156	MHHES1	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.1269096130914661	[738]	[922,980,781,930]	2	hSpCas9	negative selection	7424694
23707013	23707036	16	+	27260156	MHHES1	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.9661338081239529	[255]	[198,144,163,96]	-9	hSpCas9	negative selection	7424695
23710180	23710203	16	-	27260156	MHHES1	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.9007265600913167	[262]	[745,751,536,273]	9	hSpCas9	negative selection	7424696
23710534	23710557	16	-	27260156	MEWO	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.24438108278759918	[264]	[318,272,293]	5	hSpCas9	negative selection	7481680
23710510	23710533	16	+	27260156	MEWO	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.3668579517906543	[862]	[963,1103,1039]	7	hSpCas9	negative selection	7481681
23710939	23710962	16	-	27260156	MEWO	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.20053026280443265	[321]	[356,218,228]	-4	hSpCas9	negative selection	7481682
23711004	23711027	16	-	27260156	MEWO	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.0574279740462359	[738]	[849,616,716]	1	hSpCas9	negative selection	7545945
23707013	23707036	16	+	27260156	MEWO	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.20404467698766648	[255]	[254,185,382]	4	hSpCas9	negative selection	7545946
23710180	23710203	16	-	27260156	MEWO	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.3279049595762369	[262]	[443,235,272]	7	hSpCas9	negative selection	7545947
23710534	23710557	16	-	27260156	LNCAPCLONEFGC	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.3963718251324282	[264]	[229,275,484,301]	6	hSpCas9	negative selection	7602931
23710510	23710533	16	+	27260156	LNCAPCLONEFGC	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.04026610175687673	[862]	[765,534,960,822]	0	hSpCas9	negative selection	7602932
23710939	23710962	16	-	27260156	LNCAPCLONEFGC	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.015875384917409252	[321]	[280,337,209,309]	0	hSpCas9	negative selection	7602933
23711004	23711027	16	-	27260156	LNCAPCLONEFGC	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.2188993666239516	[738]	[701,593,1077,799]	3	hSpCas9	negative selection	7667196
23707013	23707036	16	+	27260156	LNCAPCLONEFGC	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.3128595893107592	[255]	[209,103,242,202]	-5	hSpCas9	negative selection	7667197
23710180	23710203	16	-	27260156	LNCAPCLONEFGC	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.99245955923452	[262]	[545,415,378,542]	9	hSpCas9	negative selection	7667198
23710534	23710557	16	-	27260156	PANC0327	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.30858809474269455	[264]	[500,255,311,118]	4	hSpCas9	negative selection	7724182
23710510	23710533	16	+	27260156	PANC0327	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.35803876513277855	[862]	[923,929,1061,1015]	5	hSpCas9	negative selection	7724183
23710939	23710962	16	-	27260156	PANC0327	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.2187732652811043	[321]	[274,272,244,188]	-3	hSpCas9	negative selection	7724184
23711004	23711027	16	-	27260156	PANC0327	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.41949611067558235	[738]	[854,977,896,766]	6	hSpCas9	negative selection	7788447
23707013	23707036	16	+	27260156	PANC0327	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.05832795224882481	[255]	[328,233,210,180]	0	hSpCas9	negative selection	7788448
23710180	23710203	16	-	27260156	PANC0327	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.4852291158485949	[262]	[542,124,414,268]	7	hSpCas9	negative selection	7788449
23710534	23710557	16	-	27260156	NCIH2009	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.9024730226719769	[264]	[766,906,411]	9	hSpCas9	negative selection	7845433
23710510	23710533	16	+	27260156	NCIH2009	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.15211211492775878	[862]	[1513,875,951]	-2	hSpCas9	negative selection	7845434
23710939	23710962	16	-	27260156	NCIH2009	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.1526314199219415	[321]	[825,380,358]	2	hSpCas9	negative selection	7845435
23711004	23711027	16	-	27260156	NCIH2009	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.22861330771762545	[738]	[1377,964,1321]	3	hSpCas9	negative selection	7909698
23707013	23707036	16	+	27260156	NCIH2009	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.4102700582116835	[255]	[290,229,290]	-5	hSpCas9	negative selection	7909699
23710180	23710203	16	-	27260156	NCIH2009	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.8618471351093346	[262]	[966,523,572]	9	hSpCas9	negative selection	7909700
23710534	23710557	16	-	27260156	NCIH1373	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.4931797753137582	[264]	[751,325,221,114]	5	hSpCas9	negative selection	7966684
23710510	23710533	16	+	27260156	NCIH1373	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.12110694211135897	[862]	[968,930,1037,335]	1	hSpCas9	negative selection	7966685
23710939	23710962	16	-	27260156	NCIH1373	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.03455474498642597	[321]	[581,128,170,158]	0	hSpCas9	negative selection	7966686
23711004	23711027	16	-	27260156	NCIH1373	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.14329948457877473	[738]	[815,865,751,323]	1	hSpCas9	negative selection	8030949
23707013	23707036	16	+	27260156	NCIH1373	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-1.5116812879190533	[255]	[92,60,24,61]	-9	hSpCas9	negative selection	8030950
23710180	23710203	16	-	27260156	NCIH1373	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	1.307921804783628	[262]	[578,592,973,198]	9	hSpCas9	negative selection	8030951
23710534	23710557	16	-	27260156	PATU8902	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.06633354865526764	[264]	[147,679,254,512]	0	hSpCas9	negative selection	8087935
23710510	23710533	16	+	27260156	PATU8902	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.1882898123478216	[862]	[1048,1901,1297,1224]	2	hSpCas9	negative selection	8087936
23710939	23710962	16	-	27260156	PATU8902	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.08456450269941579	[321]	[737,298,464,383]	0	hSpCas9	negative selection	8087937
23711004	23711027	16	-	27260156	PATU8902	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.14986546699988945	[738]	[1422,879,1204,1013]	1	hSpCas9	negative selection	8152200
23707013	23707036	16	+	27260156	PATU8902	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.30564077850401217	[255]	[536,254,137,252]	-3	hSpCas9	negative selection	8152201
23710180	23710203	16	-	27260156	PATU8902	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.8120362675411065	[262]	[416,1025,113,1220]	8	hSpCas9	negative selection	8152202
23710534	23710557	16	-	27260156	PANC1	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	-0.20261170058859512	[264]	[206,277,196,132]	-3	hSpCas9	negative selection	8209186
23710510	23710533	16	+	27260156	PANC1	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.05958706732498398	[862]	[815,835,626,595]	-1	hSpCas9	negative selection	8209187
23710939	23710962	16	-	27260156	PANC1	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.024662826710360575	[321]	[218,318,376,224]	0	hSpCas9	negative selection	8209188
23711004	23711027	16	-	27260156	PANC1	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.2507899833245054	[738]	[694,903,813,645]	4	hSpCas9	negative selection	8273451
23707013	23707036	16	+	27260156	PANC1	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.46208301342023594	[255]	[158,127,139,195]	-6	hSpCas9	negative selection	8273452
23710180	23710203	16	-	27260156	PANC1	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.7437360188825674	[262]	[353,418,433,318]	9	hSpCas9	negative selection	8273453
23710534	23710557	16	-	27260156	PANC0813	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.5378799682518662	[264]	[370,299,408,704]	8	hSpCas9	negative selection	8330437
23710510	23710533	16	+	27260156	PANC0813	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.05039193369356354	[862]	[1275,785,998,885]	-1	hSpCas9	negative selection	8330438
23710939	23710962	16	-	27260156	PANC0813	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.12664419658159665	[321]	[388,416,294,290]	-2	hSpCas9	negative selection	8330439
23711004	23711027	16	-	27260156	PANC0813	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.02989571253458856	[738]	[899,947,975,729]	0	hSpCas9	negative selection	8394702
23707013	23707036	16	+	27260156	PANC0813	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.08291664202651228	[255]	[304,485,275,210]	1	hSpCas9	negative selection	8394703
23710180	23710203	16	-	27260156	PANC0813	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.8102440891347984	[262]	[797,571,510,320]	9	hSpCas9	negative selection	8394704
23710534	23710557	16	-	27260156	RDES	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.2971921991688916	[264]	[286,360,483,379]	5	hSpCas9	negative selection	8451688
23710510	23710533	16	+	27260156	RDES	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.25322808209942194	[862]	[595,834,1053,889]	-4	hSpCas9	negative selection	8451689
23710939	23710962	16	-	27260156	RDES	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.15063265342313936	[321]	[226,285,350,517]	-3	hSpCas9	negative selection	8451690
23711004	23711027	16	-	27260156	RDES	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.0525820389290832	[738]	[669,739,915,997]	-1	hSpCas9	negative selection	8515953
23707013	23707036	16	+	27260156	RDES	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.5614610215272352	[255]	[212,103,231,258]	-7	hSpCas9	negative selection	8515954
23710180	23710203	16	-	27260156	RDES	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.8991977716594092	[262]	[438,452,663,754]	9	hSpCas9	negative selection	8515955
23710534	23710557	16	-	27260156	PC3	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.2984509841052424	[264]	[224,239,366,505]	6	hSpCas9	negative selection	8572939
23710510	23710533	16	+	27260156	PC3	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.00826172482088472	[862]	[492,933,1518,807]	0	hSpCas9	negative selection	8572940
23710939	23710962	16	-	27260156	PC3	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.13144411234818765	[321]	[305,217,591,366]	3	hSpCas9	negative selection	8572941
23711004	23711027	16	-	27260156	PC3	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.129216744381478	[738]	[443,850,1541,755]	3	hSpCas9	negative selection	8637204
23707013	23707036	16	+	27260156	PC3	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.5152627841524252	[255]	[74,230,317,173]	-8	hSpCas9	negative selection	8637205
23710180	23710203	16	-	27260156	PC3	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.7050666070492735	[262]	[296,322,796,455]	9	hSpCas9	negative selection	8637206
23710534	23710557	16	-	27260156	PATU8988T	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.012576801365287604	[264]	[238,360,173,270]	0	hSpCas9	negative selection	8694190
23710510	23710533	16	+	27260156	PATU8988T	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	0.2258446745756555	[862]	[784,1425,934,781]	4	hSpCas9	negative selection	8694191
23710939	23710962	16	-	27260156	PATU8988T	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.19003530608489583	[321]	[271,296,326,532]	3	hSpCas9	negative selection	8694192
23711004	23711027	16	-	27260156	PATU8988T	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.04258568642168614	[738]	[598,968,628,770]	0	hSpCas9	negative selection	8758455
23707013	23707036	16	+	27260156	PATU8988T	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.0956512718821233	[255]	[310,259,147,208]	-2	hSpCas9	negative selection	8758456
23710180	23710203	16	-	27260156	PATU8988T	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.763931983045052	[262]	[513,455,453,292]	9	hSpCas9	negative selection	8758457
23710534	23710557	16	-	27260156	T47D	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.2677848578939137	[264]	[383,343,364,396]	6	hSpCas9	negative selection	8815441
23710510	23710533	16	+	27260156	T47D	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.04575905584828943	[862]	[992,962,921,1020]	-1	hSpCas9	negative selection	8815442
23710939	23710962	16	-	27260156	T47D	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.31426262107264413	[321]	[280,281,315,329]	-6	hSpCas9	negative selection	8815443
23711004	23711027	16	-	27260156	T47D	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	-0.027342354874352437	[738]	[965,824,716,875]	0	hSpCas9	negative selection	8879706
23707013	23707036	16	+	27260156	T47D	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.11797307958869163	[255]	[252,246,319,280]	-3	hSpCas9	negative selection	8879707
23710180	23710203	16	-	27260156	T47D	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.67869486957496	[262]	[420,423,545,577]	9	hSpCas9	negative selection	8879708
23710534	23710557	16	-	27260156	SU8686	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.6313101974463499	[264]	[340,314,544,454]	9	hSpCas9	negative selection	8936692
23710510	23710533	16	+	27260156	SU8686	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.059949940805713475	[862]	[661,612,851,1268]	-1	hSpCas9	negative selection	8936693
23710939	23710962	16	-	27260156	SU8686	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.4138263003844437	[321]	[287,318,499,660]	7	hSpCas9	negative selection	8936694
23711004	23711027	16	-	27260156	SU8686	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.024597681190662413	[738]	[767,590,793,859]	0	hSpCas9	negative selection	9000957
23707013	23707036	16	+	27260156	SU8686	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	0.1592889113005267	[255]	[310,205,383,231]	2	hSpCas9	negative selection	9000958
23710180	23710203	16	-	27260156	SU8686	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.4614159476256092	[262]	[222,296,430,536]	7	hSpCas9	negative selection	9000959
23710534	23710557	16	-	27260156	SKES1	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.5658405397209011	[264]	[450,422,368,336]	9	hSpCas9	negative selection	9057943
23710510	23710533	16	+	27260156	SKES1	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.06041580393034229	[862]	[819,1055,775,685]	-1	hSpCas9	negative selection	9057944
23710939	23710962	16	-	27260156	SKES1	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.038415411781122066	[321]	[286,373,319,274]	-1	hSpCas9	negative selection	9057945
23711004	23711027	16	-	27260156	SKES1	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.02803545970262855	[738]	[862,818,774,584]	0	hSpCas9	negative selection	9122208
23707013	23707036	16	+	27260156	SKES1	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.10639772656927271	[255]	[242,240,270,196]	-2	hSpCas9	negative selection	9122209
23710180	23710203	16	-	27260156	SKES1	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.5712674612016957	[262]	[488,426,300,360]	9	hSpCas9	negative selection	9122210
23710534	23710557	16	-	27260156	TOV112D	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.5370317001265676	[264]	[448,499,331,294]	8	hSpCas9	negative selection	9179194
23710510	23710533	16	+	27260156	TOV112D	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.3272468996436094	[862]	[719,875,582,625]	-6	hSpCas9	negative selection	9179195
23710939	23710962	16	-	27260156	TOV112D	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.22092629058501773	[321]	[225,747,383,227]	4	hSpCas9	negative selection	9179196
23711004	23711027	16	-	27260156	TOV112D	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.059459709337440825	[738]	[667,838,1036,553]	1	hSpCas9	negative selection	9243459
23707013	23707036	16	+	27260156	TOV112D	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.46993078123892384	[255]	[175,169,179,208]	-7	hSpCas9	negative selection	9243460
23710180	23710203	16	-	27260156	TOV112D	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.7700892894239403	[262]	[494,398,567,328]	9	hSpCas9	negative selection	9243461
23710534	23710557	16	-	27260156	TC71	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.4431968038796303	[264]	[420,400,343,378]	8	hSpCas9	negative selection	9300445
23710510	23710533	16	+	27260156	TC71	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.16303278390909548	[862]	[749,862,808,888]	-4	hSpCas9	negative selection	9300446
23710939	23710962	16	-	27260156	TC71	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	-0.10751547640670067	[321]	[318,352,314,292]	-3	hSpCas9	negative selection	9300447
23711004	23711027	16	-	27260156	TC71	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.15039748329617364	[738]	[835,797,778,1122]	4	hSpCas9	negative selection	9364710
23707013	23707036	16	+	27260156	TC71	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.3239884043528133	[255]	[216,241,194,223]	-7	hSpCas9	negative selection	9364711
23710180	23710203	16	-	27260156	TC71	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.530870952742217	[262]	[437,421,342,428]	9	hSpCas9	negative selection	9364712
23710534	23710557	16	-	27260156	TC32	viability	CCTGCAGATCCCGTCATCGAAGG	ERN2	ENSG00000134398	0.04505033896123167	[264]	[272,139,367,295]	0	hSpCas9	negative selection	9421696
23710510	23710533	16	+	27260156	TC32	viability	ACTTACTCTGTGACGTACATTGG	ERN2	ENSG00000134398	-0.0651751308996229	[862]	[671,608,1069,833]	-1	hSpCas9	negative selection	9421697
23710939	23710962	16	-	27260156	TC32	viability	CACGCACTAAGCAAGCAGACAGG	ERN2	ENSG00000134398	0.11540840717368867	[321]	[308,311,339,339]	2	hSpCas9	negative selection	9421698
23711004	23711027	16	-	27260156	TC32	viability	CCTTGCAGGTTCATACTCTCAGG	ERN2	ENSG00000134398	0.10517090749389457	[738]	[716,549,961,834]	2	hSpCas9	negative selection	9485961
23707013	23707036	16	+	27260156	TC32	viability	AGAAGACCCCATCAGAGCTGCGG	ERN2	ENSG00000134398	-0.017635473493577858	[255]	[270,169,271,250]	0	hSpCas9	negative selection	9485962
23710180	23710203	16	-	27260156	TC32	viability	CTTGGGGACCCAAAAACAACAGG	ERN2	ENSG00000134398	0.7443266141645044	[262]	[420,306,546,418]	9	hSpCas9	negative selection	9485963
23704998	23705021	16	+	27869803	HPAFII	viability after 27 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.08590127157723182	[173]	[143,57,NaN]	0	hSpCas9	negative selection	9556262
23706372	23706395	16	+	27869803	HPAFII	viability after 27 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-1.620613312809305	[242]	[22,56,NaN]	-7	hSpCas9	negative selection	9556263
23706755	23706778	16	+	27869803	HPAFII	viability after 27 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.5653974366843234	[241]	[100,260,NaN]	4	hSpCas9	negative selection	9556264
23710970	23710993	16	+	27869803	HPAFII	viability after 27 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.5254628362990464	[168]	[76,48,NaN]	-4	hSpCas9	negative selection	9556265
23713174	23713197	16	+	27869803	HPAFII	viability after 27 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.4209837276597262	[170]	[169,78,NaN]	3	hSpCas9	negative selection	9556266
23704998	23705021	16	+	27869803	HPAFII	viability after 15 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.7438093822767091	[173]	[351,288,NaN]	8	hSpCas9	negative selection	9638711
23706372	23706395	16	+	27869803	HPAFII	viability after 15 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-1.5171039690133974	[242]	[44,119,NaN]	-8	hSpCas9	negative selection	9638712
23706755	23706778	16	+	27869803	HPAFII	viability after 15 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.10649101182619396	[241]	[197,330,NaN]	1	hSpCas9	negative selection	9638713
23710970	23710993	16	+	27869803	HPAFII	viability after 15 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.013637997271667812	[168]	[219,154,NaN]	0	hSpCas9	negative selection	9638714
23713174	23713197	16	+	27869803	HPAFII	viability after 15 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.6444294534161977	[170]	[306,274,NaN]	7	hSpCas9	negative selection	9638715
23704998	23705021	16	+	27869803	ASPC1	viability after 36 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	-0.03885592330348664	[637]	[165,415,91]	0	hSpCas9	negative selection	9721160
23706372	23706395	16	+	27869803	ASPC1	viability after 36 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-1.6109096013387043	[391]	[35,86,16]	-8	hSpCas9	negative selection	9721161
23706755	23706778	16	+	27869803	ASPC1	viability after 36 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	-0.3843388278011461	[671]	[176,259,115]	-4	hSpCas9	negative selection	9721162
23710970	23710993	16	+	27869803	ASPC1	viability after 36 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-1.0508989972133462	[492]	[56,94,90]	-7	hSpCas9	negative selection	9721163
23713174	23713197	16	+	27869803	ASPC1	viability after 36 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.8037047573055706	[367]	[63,308,266]	7	hSpCas9	negative selection	9721164
23704998	23705021	16	+	27869803	PATU8988S	viability after 35 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	1.1311326083457973	[449]	[600,191,NaN]	9	hSpCas9	negative selection	9803609
23706372	23706395	16	+	27869803	PATU8988S	viability after 35 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.7731146825477417	[384]	[259,269,NaN]	8	hSpCas9	negative selection	9803610
23706755	23706778	16	+	27869803	PATU8988S	viability after 35 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	-0.7102397015543117	[632]	[78,232,NaN]	-6	hSpCas9	negative selection	9803611
23710970	23710993	16	+	27869803	PATU8988S	viability after 35 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	0.050949116588848875	[441]	[146,221,NaN]	0	hSpCas9	negative selection	9803612
23713174	23713197	16	+	27869803	PATU8988S	viability after 35 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	-0.335395207598716	[318]	[25,177,NaN]	-4	hSpCas9	negative selection	9803613
23704998	23705021	16	+	27869803	PATU8988S	viability after 31 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	1.1306718847293065	[449]	[446,323,NaN]	9	hSpCas9	negative selection	9886058
23706372	23706395	16	+	27869803	PATU8988S	viability after 31 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	0.9678574303488454	[384]	[239,376,NaN]	9	hSpCas9	negative selection	9886059
23706755	23706778	16	+	27869803	PATU8988S	viability after 31 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	-0.6345639664692929	[632]	[78,268,NaN]	-6	hSpCas9	negative selection	9886060
23710970	23710993	16	+	27869803	PATU8988S	viability after 31 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	0.2483010170619229	[441]	[134,303,NaN]	3	hSpCas9	negative selection	9886061
23713174	23713197	16	+	27869803	PATU8988S	viability after 31 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.23573435742468052	[318]	[41,286,NaN]	3	hSpCas9	negative selection	9886062
23704998	23705021	16	+	27869803	HPAFII	viability after 35 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.470863613340747	[173]	[170,66,NaN]	3	hSpCas9	negative selection	9968507
23706372	23706395	16	+	27869803	HPAFII	viability after 35 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-1.8859416760697354	[242]	[13,54,NaN]	-7	hSpCas9	negative selection	9968508
23706755	23706778	16	+	27869803	HPAFII	viability after 35 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.9709472647420565	[241]	[162,326,NaN]	6	hSpCas9	negative selection	9968509
23710970	23710993	16	+	27869803	HPAFII	viability after 35 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.862625646871788	[168]	[31,63,NaN]	-5	hSpCas9	negative selection	9968510
23713174	23713197	16	+	27869803	HPAFII	viability after 35 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.8127261739336993	[170]	[152,150,NaN]	5	hSpCas9	negative selection	9968511
23704998	23705021	16	+	27869803	HPAFII	viability after 31 days	TGAGATGCGGCAGCTGGCGCAGG	ERN2	ENSG00000134398	0.2978334556772254	[173]	[187,45,NaN]	2	hSpCas9	negative selection	10050956
23706372	23706395	16	+	27869803	HPAFII	viability after 31 days	GGTAGGTGGTGTTCCAGCGCAGG	ERN2	ENSG00000134398	-1.4983436857116883	[242]	[31,65,NaN]	-7	hSpCas9	negative selection	10050957
23706755	23706778	16	+	27869803	HPAFII	viability after 31 days	TGTTCGGCCAATGTAGAGGCGGG	ERN2	ENSG00000134398	0.9200122151640293	[241]	[155,366,NaN]	7	hSpCas9	negative selection	10050958
23710970	23710993	16	+	27869803	HPAFII	viability after 31 days	CATCCAAGGTGGACACCAGCAGG	ERN2	ENSG00000134398	-0.8882292235943684	[168]	[11,93,NaN]	-5	hSpCas9	negative selection	10050959
23713174	23713197	16	+	27869803	HPAFII	viability after 31 days	ACCGCACTCGCCATAGCGCCTGG	ERN2	ENSG00000134398	0.573587328541885	[170]	[216,61,NaN]	4	hSpCas9	negative selection	10050960
23692247	23692270	16	+	28162770	P31FUJ	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.4027863693767456	[111]	[173]	4	hSpCas9	negative selection	10151250
23706377	23706400	16	+	28162770	P31FUJ	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.633399297518162	[174]	[318]	7	hSpCas9	negative selection	10151251
23713319	23713342	16	-	28162770	P31FUJ	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.1186701660869991	[57]	[73]	1	hSpCas9	negative selection	10151252
23713307	23713330	16	-	28162770	P31FUJ	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.7473753772441372	[9]	[6]	-5	hSpCas9	negative selection	10151253
23713271	23713294	16	-	28162770	P31FUJ	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.2205238746359418	[233]	[235]	-2	hSpCas9	negative selection	10151254
23707044	23707067	16	+	28162770	P31FUJ	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.9321427262806676	[163]	[100]	-6	hSpCas9	negative selection	10151255
23706832	23706855	16	-	28162770	P31FUJ	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.5911892391297822	[504]	[893]	6	hSpCas9	negative selection	10151256
23706790	23706813	16	-	28162770	P31FUJ	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.3987780852797346	[405]	[628]	4	hSpCas9	negative selection	10151257
23706754	23706777	16	+	28162770	P31FUJ	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.9682312842784889	[417]	[960]	9	hSpCas9	negative selection	10151258
23706385	23706408	16	-	28162770	P31FUJ	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	0.5507059756888577	[60]	[104]	6	hSpCas9	negative selection	10151259
23692247	23692270	16	+	28162770	TF1	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10320616
23706377	23706400	16	+	28162770	TF1	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10320617
23713319	23713342	16	-	28162770	TF1	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10320618
23713307	23713330	16	-	28162770	TF1	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10320619
23713271	23713294	16	-	28162770	TF1	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10320620
23707044	23707067	16	+	28162770	TF1	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10320621
23706832	23706855	16	-	28162770	TF1	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10320622
23706790	23706813	16	-	28162770	TF1	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	NaN	[NaN]	[347]	1	hSpCas9	negative selection	10320623
23706754	23706777	16	+	28162770	TF1	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	NaN	[NaN]	[645]	1	hSpCas9	negative selection	10320624
23706385	23706408	16	-	28162770	TF1	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10320625
23692247	23692270	16	+	28162770	SKM1	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.40039072331444236	[50]	[118]	4	hSpCas9	negative selection	10489982
23706377	23706400	16	+	28162770	SKM1	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.347923303420307	[31]	[71]	3	hSpCas9	negative selection	10489983
23713319	23713342	16	-	28162770	SKM1	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.8560702070906323	[14]	[47]	7	hSpCas9	negative selection	10489984
23713307	23713330	16	-	28162770	SKM1	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.01464677596440156	[3]	[6]	0	hSpCas9	negative selection	10489985
23713271	23713294	16	-	28162770	SKM1	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.34951392655926206	[79]	[110]	-3	hSpCas9	negative selection	10489986
23707044	23707067	16	+	28162770	SKM1	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.8559490299453432	[42]	[41]	-6	hSpCas9	negative selection	10489987
23706832	23706855	16	-	28162770	SKM1	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.41760685889097715	[118]	[280]	4	hSpCas9	negative selection	10489988
23706790	23706813	16	-	28162770	SKM1	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.5359547060495709	[86]	[222]	5	hSpCas9	negative selection	10489989
23706754	23706777	16	+	28162770	SKM1	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.12196426706366648	[104]	[201]	1	hSpCas9	negative selection	10489990
23706385	23706408	16	-	28162770	SKM1	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	-2.8220016980220053	[11]	[2]	-9	hSpCas9	negative selection	10489991
23692247	23692270	16	+	28162770	SKM1	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.40039072331444236	[50]	[118]	4	hSpCas9	negative selection	10659348
23706377	23706400	16	+	28162770	SKM1	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.347923303420307	[31]	[71]	3	hSpCas9	negative selection	10659349
23713319	23713342	16	-	28162770	SKM1	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.8560702070906323	[14]	[47]	7	hSpCas9	negative selection	10659350
23713307	23713330	16	-	28162770	SKM1	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.01464677596440156	[3]	[6]	0	hSpCas9	negative selection	10659351
23713271	23713294	16	-	28162770	SKM1	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.34951392655926206	[79]	[110]	-3	hSpCas9	negative selection	10659352
23707044	23707067	16	+	28162770	SKM1	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.8559490299453432	[42]	[41]	-6	hSpCas9	negative selection	10659353
23706832	23706855	16	-	28162770	SKM1	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.41760685889097715	[118]	[280]	4	hSpCas9	negative selection	10659354
23706790	23706813	16	-	28162770	SKM1	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.5359547060495709	[86]	[222]	5	hSpCas9	negative selection	10659355
23706754	23706777	16	+	28162770	SKM1	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.12196426706366648	[104]	[201]	1	hSpCas9	negative selection	10659356
23706385	23706408	16	-	28162770	SKM1	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	-2.8220016980220053	[11]	[2]	-9	hSpCas9	negative selection	10659357
23692247	23692270	16	+	28162770	PL21	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	-0.04963869464220696	[194]	[81]	0	hSpCas9	negative selection	10828714
23706377	23706400	16	+	28162770	PL21	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.9093602181726221	[125]	[102]	7	hSpCas9	negative selection	10828715
23713319	23713342	16	-	28162770	PL21	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.7041821198269087	[54]	[38]	6	hSpCas9	negative selection	10828716
23713307	23713330	16	-	28162770	PL21	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-2.6072153075682842	[13]	[0]	-9	hSpCas9	negative selection	10828717
23713271	23713294	16	-	28162770	PL21	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	0.08971562479566964	[284]	[131]	0	hSpCas9	negative selection	10828718
23707044	23707067	16	+	28162770	PL21	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.30236072603986314	[152]	[53]	-2	hSpCas9	negative selection	10828719
23706832	23706855	16	-	28162770	PL21	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	1.4342138408734038	[368]	[433]	9	hSpCas9	negative selection	10828720
23706790	23706813	16	-	28162770	PL21	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	1.1333081060111114	[242]	[231]	8	hSpCas9	negative selection	10828721
23706754	23706777	16	+	28162770	PL21	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.018355529178690988	[396]	[174]	0	hSpCas9	negative selection	10828722
23706385	23706408	16	-	28162770	PL21	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	-2.1921778082894408	[41]	[3]	-8	hSpCas9	negative selection	10828723
23692247	23692270	16	+	28162770	P31FUJ	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.4027863693767456	[111]	[173]	4	hSpCas9	negative selection	10998080
23706377	23706400	16	+	28162770	P31FUJ	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.633399297518162	[174]	[318]	7	hSpCas9	negative selection	10998081
23713319	23713342	16	-	28162770	P31FUJ	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.1186701660869991	[57]	[73]	1	hSpCas9	negative selection	10998082
23713307	23713330	16	-	28162770	P31FUJ	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.7473753772441372	[9]	[6]	-5	hSpCas9	negative selection	10998083
23713271	23713294	16	-	28162770	P31FUJ	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.2205238746359418	[233]	[235]	-2	hSpCas9	negative selection	10998084
23707044	23707067	16	+	28162770	P31FUJ	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.9321427262806676	[163]	[100]	-6	hSpCas9	negative selection	10998085
23706832	23706855	16	-	28162770	P31FUJ	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.5911892391297822	[504]	[893]	6	hSpCas9	negative selection	10998086
23706790	23706813	16	-	28162770	P31FUJ	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.3987780852797346	[405]	[628]	4	hSpCas9	negative selection	10998087
23706754	23706777	16	+	28162770	P31FUJ	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.9682312842784889	[417]	[960]	9	hSpCas9	negative selection	10998088
23706385	23706408	16	-	28162770	P31FUJ	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	0.5507059756888577	[60]	[104]	6	hSpCas9	negative selection	10998089
23692247	23692270	16	+	28162770	OCIAML5	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	-0.27217505969026284	[94]	[141]	-2	hSpCas9	negative selection	11167446
23706377	23706400	16	+	28162770	OCIAML5	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.2903776941562083	[52]	[116]	2	hSpCas9	negative selection	11167447
23713319	23713342	16	-	28162770	OCIAML5	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-0.6630327464739803	[49]	[56]	-4	hSpCas9	negative selection	11167448
23713307	23713330	16	-	28162770	OCIAML5	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-4.552506289005089	[12]	[0]	-9	hSpCas9	negative selection	11167449
23713271	23713294	16	-	28162770	OCIAML5	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-3.4022636534244763	[204]	[34]	-9	hSpCas9	negative selection	11167450
23707044	23707067	16	+	28162770	OCIAML5	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-1.1415731880589817	[43]	[35]	-6	hSpCas9	negative selection	11167451
23706832	23706855	16	-	28162770	OCIAML5	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	-0.14383269524110665	[354]	[579]	-1	hSpCas9	negative selection	11167452
23706790	23706813	16	-	28162770	OCIAML5	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.6285592700424235	[214]	[599]	5	hSpCas9	negative selection	11167453
23706754	23706777	16	+	28162770	OCIAML5	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.4915862951780814	[289]	[735]	4	hSpCas9	negative selection	11167454
23706385	23706408	16	-	28162770	OCIAML5	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	0.7328959298571591	[25]	[77]	6	hSpCas9	negative selection	11167455
23692247	23692270	16	+	28162770	EOL1	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.49473491961129246	[228]	[169]	4	hSpCas9	negative selection	11336812
23706377	23706400	16	+	28162770	EOL1	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	1.0407407890750573	[154]	[167]	8	hSpCas9	negative selection	11336813
23713319	23713342	16	-	28162770	EOL1	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-0.8468278533815032	[98]	[28]	-5	hSpCas9	negative selection	11336814
23713307	23713330	16	-	28162770	EOL1	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.4290891830441663	[22]	[8]	-3	hSpCas9	negative selection	11336815
23713271	23713294	16	-	28162770	EOL1	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.21122900745993234	[500]	[227]	-2	hSpCas9	negative selection	11336816
23707044	23707067	16	+	28162770	EOL1	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-1.1700891025675406	[251]	[58]	-7	hSpCas9	negative selection	11336817
23706832	23706855	16	-	28162770	EOL1	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.5920697573422621	[548]	[435]	5	hSpCas9	negative selection	11336818
23706790	23706813	16	-	28162770	EOL1	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	-0.32972871078569954	[426]	[178]	-2	hSpCas9	negative selection	11336819
23706754	23706777	16	+	28162770	EOL1	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	1.0528022622429758	[440]	[481]	8	hSpCas9	negative selection	11336820
23706385	23706408	16	-	28162770	EOL1	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	0.19662731700733538	[52]	[31]	1	hSpCas9	negative selection	11336821
23692247	23692270	16	+	28162770	MOLM13	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	1.061264122081935	[227]	[343]	7	hSpCas9	negative selection	11506178
23706377	23706400	16	+	28162770	MOLM13	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	2.0046958441110827	[131]	[382]	9	hSpCas9	negative selection	11506179
23713319	23713342	16	-	28162770	MOLM13	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-2.548412430784522	[88]	[10]	-8	hSpCas9	negative selection	11506180
23713307	23713330	16	-	28162770	MOLM13	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	3.0528518822657347	[4]	[29]	9	hSpCas9	negative selection	11506181
23713271	23713294	16	-	28162770	MOLM13	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-1.4287328786101126	[349]	[93]	-6	hSpCas9	negative selection	11506182
23707044	23707067	16	+	28162770	MOLM13	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	0.5754178458490239	[167]	[180]	4	hSpCas9	negative selection	11506183
23706832	23706855	16	-	28162770	MOLM13	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.27399467594424554	[659]	[576]	2	hSpCas9	negative selection	11506184
23706790	23706813	16	-	28162770	MOLM13	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	1.0385225134949332	[370]	[550]	7	hSpCas9	negative selection	11506185
23706754	23706777	16	+	28162770	MOLM13	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.022914598111631213	[421]	[309]	0	hSpCas9	negative selection	11506186
23706385	23706408	16	-	28162770	MOLM13	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	-1.1170731191765773	[74]	[24]	-5	hSpCas9	negative selection	11506187
23692247	23692270	16	+	28162770	HEL	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.48354023715110317	[200]	[179]	4	hSpCas9	negative selection	11675544
23706377	23706400	16	+	28162770	HEL	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.8106834693144284	[161]	[181]	7	hSpCas9	negative selection	11675545
23713319	23713342	16	-	28162770	HEL	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.16880764366794487	[49]	[35]	1	hSpCas9	negative selection	11675546
23713307	23713330	16	-	28162770	HEL	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-0.5796535893360915	[6]	[2]	-4	hSpCas9	negative selection	11675547
23713271	23713294	16	-	28162770	HEL	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.5066387920378699	[365]	[164]	-3	hSpCas9	negative selection	11675548
23707044	23707067	16	+	28162770	HEL	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.394350486734863	[196]	[95]	-3	hSpCas9	negative selection	11675549
23706832	23706855	16	-	28162770	HEL	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.3295809467407267	[491]	[395]	2	hSpCas9	negative selection	11675550
23706790	23706813	16	-	28162770	HEL	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	-0.24111957339049	[333]	[180]	-2	hSpCas9	negative selection	11675551
23706754	23706777	16	+	28162770	HEL	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.2413059302781947	[386]	[292]	2	hSpCas9	negative selection	11675552
23706385	23706408	16	-	28162770	HEL	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	-1.2832605865558664	[75]	[19]	-6	hSpCas9	negative selection	11675553
23692247	23692270	16	+	28162770	MV411	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	-0.7283149029705474	[176]	[89]	-5	hSpCas9	negative selection	11844910
23706377	23706400	16	+	28162770	MV411	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.42904435727272305	[81]	[92]	4	hSpCas9	negative selection	11844911
23713319	23713342	16	-	28162770	MV411	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	0.9782509179673861	[46]	[77]	8	hSpCas9	negative selection	11844912
23713307	23713330	16	-	28162770	MV411	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	0.8324000515039316	[1]	[2]	7	hSpCas9	negative selection	11844913
23713271	23713294	16	-	28162770	MV411	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.20976940274000822	[242]	[176]	-2	hSpCas9	negative selection	11844914
23707044	23707067	16	+	28162770	MV411	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.27016968213661613	[135]	[94]	-2	hSpCas9	negative selection	11844915
23706832	23706855	16	-	28162770	MV411	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.30075336531523167	[424]	[440]	2	hSpCas9	negative selection	11844916
23706790	23706813	16	-	28162770	MV411	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.34365286604207845	[260]	[278]	3	hSpCas9	negative selection	11844917
23706754	23706777	16	+	28162770	MV411	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.17784727859770233	[360]	[343]	1	hSpCas9	negative selection	11844918
23706385	23706408	16	-	28162770	MV411	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	0.8324000515039316	[43]	[65]	7	hSpCas9	negative selection	11844919
23692247	23692270	16	+	28162770	MONOMAC1	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.016207192062708903	[112]	[130]	0	hSpCas9	negative selection	12014276
23706377	23706400	16	+	28162770	MONOMAC1	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.04242908763583575	[71]	[84]	0	hSpCas9	negative selection	12014277
23713319	23713342	16	-	28162770	MONOMAC1	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-0.849113543639247	[21]	[13]	-6	hSpCas9	negative selection	12014278
23713307	23713330	16	-	28162770	MONOMAC1	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-3.78199934778071	[11]	[0]	-9	hSpCas9	negative selection	12014279
23713271	23713294	16	-	28162770	MONOMAC1	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.6406434985351684	[169]	[124]	-5	hSpCas9	negative selection	12014280
23707044	23707067	16	+	28162770	MONOMAC1	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-1.0344838342735938	[108]	[60]	-7	hSpCas9	negative selection	12014281
23706832	23706855	16	-	28162770	MONOMAC1	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.1695602971615371	[317]	[409]	1	hSpCas9	negative selection	12014282
23706790	23706813	16	-	28162770	MONOMAC1	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.13794740065325517	[175]	[221]	1	hSpCas9	negative selection	12014283
23706754	23706777	16	+	28162770	MONOMAC1	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.407734134741783	[216]	[329]	4	hSpCas9	negative selection	12014284
23706385	23706408	16	-	28162770	MONOMAC1	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	1.1248912478278086	[21]	[54]	8	hSpCas9	negative selection	12014285
23692247	23692270	16	+	28162770	OCIAML2	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.022410186037955637	[26]	[151]	0	hSpCas9	negative selection	12183642
23706377	23706400	16	+	28162770	OCIAML2	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	0.18472200337039302	[19]	[125]	1	hSpCas9	negative selection	12183643
23713319	23713342	16	-	28162770	OCIAML2	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-0.47062982524216124	[10]	[43]	-4	hSpCas9	negative selection	12183644
23713307	23713330	16	-	28162770	OCIAML2	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-4.0555923259633175	[2]	[0]	-9	hSpCas9	negative selection	12183645
23713271	23713294	16	-	28162770	OCIAML2	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	-0.31412533956217037	[47]	[213]	-3	hSpCas9	negative selection	12183646
23707044	23707067	16	+	28162770	OCIAML2	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.7436483196485772	[28]	[95]	-5	hSpCas9	negative selection	12183647
23706832	23706855	16	-	28162770	OCIAML2	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.29664765744010757	[72]	[496]	3	hSpCas9	negative selection	12183648
23706790	23706813	16	-	28162770	OCIAML2	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	-0.021322423878571417	[51]	[283]	0	hSpCas9	negative selection	12183649
23706754	23706777	16	+	28162770	OCIAML2	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	0.4548028303757615	[66]	[508]	4	hSpCas9	negative selection	12183650
23706385	23706408	16	-	28162770	OCIAML2	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	1.1276294980924528	[8]	[108]	9	hSpCas9	negative selection	12183651
23692247	23692270	16	+	28162770	OCIAML3	viability	AAAGACTGTCTCCAAAGGGGTGG	ERN2	ENSG00000134398	0.2556580865914053	[47]	[172]	2	hSpCas9	negative selection	12353008
23706377	23706400	16	+	28162770	OCIAML3	viability	GTGGTGTTCCAGCGCAGGGCTGG	ERN2	ENSG00000134398	1.3943105546282015	[30]	[245]	9	hSpCas9	negative selection	12353009
23713319	23713342	16	-	28162770	OCIAML3	viability	TGGGAGTGTGATGAGAAGGGCGG	ERN2	ENSG00000134398	-1.352999540820368	[10]	[12]	-7	hSpCas9	negative selection	12353010
23713307	23713330	16	-	28162770	OCIAML3	viability	GAGAAGGGCGGGGATCGGCGAGG	ERN2	ENSG00000134398	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12353011
23713271	23713294	16	-	28162770	OCIAML3	viability	GTTGCAGGCCCAGCCAGGGGCGG	ERN2	ENSG00000134398	0.6550875745517569	[64]	[308]	6	hSpCas9	negative selection	12353012
23707044	23707067	16	+	28162770	OCIAML3	viability	GGCATGAACCAGCTCAGGGATGG	ERN2	ENSG00000134398	-0.24442320253393524	[30]	[78]	-2	hSpCas9	negative selection	12353013
23706832	23706855	16	-	28162770	OCIAML3	viability	GCAGGATGCCTGGTTTGTGGTGG	ERN2	ENSG00000134398	0.17027855984155527	[135]	[461]	1	hSpCas9	negative selection	12353014
23706790	23706813	16	-	28162770	OCIAML3	viability	CCAGATGACACTGACCACAGAGG	ERN2	ENSG00000134398	0.3573824154512152	[82]	[320]	3	hSpCas9	negative selection	12353015
23706754	23706777	16	+	28162770	OCIAML3	viability	GTGTTCGGCCAATGTAGAGGCGG	ERN2	ENSG00000134398	-0.30896461355660954	[102]	[250]	-2	hSpCas9	negative selection	12353016
23706385	23706408	16	-	28162770	OCIAML3	viability	CAAGAGCCCCAGCCCTGCGCTGG	ERN2	ENSG00000134398	0.02490219232033053	[13]	[42]	0	hSpCas9	negative selection	12353017