Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2145
• Symbol:EZH1
• Description:enhancer of zeste 1 polycomb repressive complex 2 subunit

DataSource: http://genomecrispr.dkfz.de/#!/results/EZH1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
42720366	42720389	17	-	26472758	Jiyoye	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.2712919534241004	[88]	[80]	2	hSpCas9	negative selection	52664
42713235	42713258	17	-	26472758	Jiyoye	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-2.6151924315225816	[64]	[7]	-9	hSpCas9	negative selection	52665
42718036	42718059	17	+	26472758	Jiyoye	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-0.5928246184941273	[1]	[0]	-4	hSpCas9	negative selection	52666
42713256	42713279	17	-	26472758	Jiyoye	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	-0.1353518528948863	[133]	[91]	-1	hSpCas9	negative selection	52667
42712381	42712404	17	-	26472758	Jiyoye	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.24993563969467636	[183]	[164]	2	hSpCas9	negative selection	52668
42706150	42706173	17	+	26472758	Jiyoye	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-1.114361739073649	[88]	[30]	-6	hSpCas9	negative selection	52669
42706048	42706071	17	-	26472758	Jiyoye	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-1.4293258862112475	[24]	[6]	-7	hSpCas9	negative selection	52670
42724323	42724346	17	+	26472758	Jiyoye	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-0.4553210947441917	[59]	[32]	-3	hSpCas9	negative selection	52671
42718524	42718547	17	-	26472758	Jiyoye	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.07108572708736371	[240]	[172]	0	hSpCas9	negative selection	52672
42718466	42718489	17	+	26472758	Jiyoye	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.007862117772970523	[151]	[113]	0	hSpCas9	negative selection	52673
42720366	42720389	17	-	26472758	KBM7	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.4346259857630568	[281,179]	[98,60]	-4	hSpCas9	negative selection	243782
42713235	42713258	17	-	26472758	KBM7	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-1.5895012720297599	[349,358]	[41,67]	-8	hSpCas9	negative selection	243783
42718036	42718059	17	+	26472758	KBM7	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	0.4691459600129333	[40,12]	[2,28]	5	hSpCas9	negative selection	243784
42713256	42713279	17	-	26472758	KBM7	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	-0.3464949505146486	[574,468]	[201,182]	-3	hSpCas9	negative selection	243785
42712381	42712404	17	-	26472758	KBM7	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	-0.02198883472730695	[684,509]	[275,271]	0	hSpCas9	negative selection	243786
42706150	42706173	17	+	26472758	KBM7	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.954706631700043	[333,139]	[38,69]	-6	hSpCas9	negative selection	243787
42706048	42706071	17	-	26472758	KBM7	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-1.6004126340079061	[57,96]	[23,1]	-8	hSpCas9	negative selection	243788
42724323	42724346	17	+	26472758	KBM7	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	0.7818294551199243	[117,88]	[37,122]	8	hSpCas9	negative selection	243789
42718524	42718547	17	-	26472758	KBM7	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.3351750317371883	[822,850]	[466,528]	3	hSpCas9	negative selection	243790
42718466	42718489	17	+	26472758	KBM7	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.18958197327833215	[665,598]	[348,329]	2	hSpCas9	negative selection	243791
42720366	42720389	17	-	26472758	Raji	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.5224210346524432	[137]	[45]	5	hSpCas9	negative selection	434900
42713235	42713258	17	-	26472758	Raji	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-2.284933887405161	[146]	[6]	-9	hSpCas9	negative selection	434901
42718036	42718059	17	+	26472758	Raji	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	0.3000286133159955	[27]	[7]	3	hSpCas9	negative selection	434902
42713256	42713279	17	-	26472758	Raji	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	1.0542721989140371	[165]	[79]	8	hSpCas9	negative selection	434903
42712381	42712404	17	-	26472758	Raji	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	-0.36752541988264287	[327]	[58]	-3	hSpCas9	negative selection	434904
42706150	42706173	17	+	26472758	Raji	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.2501684692444843	[81]	[15]	-2	hSpCas9	negative selection	434905
42706048	42706071	17	-	26472758	Raji	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-0.11500888596284842	[27]	[5]	-1	hSpCas9	negative selection	434906
42724323	42724346	17	+	26472758	Raji	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-1.6702240432899529	[95]	[6]	-8	hSpCas9	negative selection	434907
42718524	42718547	17	-	26472758	Raji	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.5327629788739023	[416]	[139]	5	hSpCas9	negative selection	434908
42718466	42718489	17	+	26472758	Raji	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.5131132924262154	[310]	[102]	5	hSpCas9	negative selection	434909
42720366	42720389	17	-	26472758	K562	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.4475816775228422	[204]	[235]	3	hSpCas9	negative selection	626018
42713235	42713258	17	-	26472758	K562	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-2.9869068184400085	[215]	[22]	-8	hSpCas9	negative selection	626019
42718036	42718059	17	+	26472758	K562	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-4.510468774497021	[26]	[0]	-9	hSpCas9	negative selection	626020
42713256	42713279	17	-	26472758	K562	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	-0.7082755575551964	[479]	[247]	-4	hSpCas9	negative selection	626021
42712381	42712404	17	-	26472758	K562	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.7106436818040802	[442]	[611]	6	hSpCas9	negative selection	626022
42706150	42706173	17	+	26472758	K562	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.3460607780222751	[130]	[86]	-2	hSpCas9	negative selection	626023
42706048	42706071	17	-	26472758	K562	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	0.39126011599571786	[27]	[30]	3	hSpCas9	negative selection	626024
42724323	42724346	17	+	26472758	K562	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-1.552594250169698	[138]	[39]	-6	hSpCas9	negative selection	626025
42718524	42718547	17	-	26472758	K562	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.24879716817702113	[657]	[659]	2	hSpCas9	negative selection	626026
42718466	42718489	17	+	26472758	K562	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.1519977962257018	[418]	[392]	1	hSpCas9	negative selection	626027
42712388	42712411	17	-	26627737	DLD1	viability	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.16433819325600818	[915]	[263,117,361]	-2	hSpCas9	negative selection	797903
42713333	42713356	17	+	26627737	DLD1	viability	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-0.01813296441356771	[587]	[232,155,157]	0	hSpCas9	negative selection	797904
42718466	42718489	17	+	26627737	DLD1	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	1.3237866193943097	[122]	[91,71,119]	9	hSpCas9	negative selection	797905
42720366	42720389	17	-	26627737	DLD1	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.412243034050658	[164]	[47,29,37]	-4	hSpCas9	negative selection	797906
42722786	42722809	17	+	26627737	DLD1	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.20283809558103516	[1133]	[381,215,319]	-2	hSpCas9	negative selection	797907
42727660	42727683	17	+	26627737	DLD1	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.004545456960821648	[511]	[190,231,74]	0	hSpCas9	negative selection	797908
42712388	42712411	17	-	26627737	GBM cells	viability after 5 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.2088346683503155	[554]	[302,384]	3	hSpCas9	negative selection	880218
42713333	42713356	17	+	26627737	GBM cells	viability after 5 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-0.4732624098789602	[408]	[141,173]	-6	hSpCas9	negative selection	880219
42718466	42718489	17	+	26627737	GBM cells	viability after 5 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.06015586105943205	[138]	[68,73]	-1	hSpCas9	negative selection	880220
42720366	42720389	17	-	26627737	GBM cells	viability after 5 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.03276962162047581	[71]	[42,35]	0	hSpCas9	negative selection	880221
42722786	42722809	17	+	26627737	GBM cells	viability after 5 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.36698613648639766	[453]	[302,324]	5	hSpCas9	negative selection	880222
42727660	42727683	17	+	26627737	GBM cells	viability after 5 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.4537406576335231	[257]	[177,200]	6	hSpCas9	negative selection	880223
42712388	42712411	17	-	26627737	GBM cells	viability after 13 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.37243652516707093	[554]	[380,396]	5	hSpCas9	negative selection	962533
42713333	42713356	17	+	26627737	GBM cells	viability after 13 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-0.317107705423835	[408]	[224,139]	-4	hSpCas9	negative selection	962534
42718466	42718489	17	+	26627737	GBM cells	viability after 13 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.7033936945100618	[138]	[58,35]	-7	hSpCas9	negative selection	962535
42720366	42720389	17	-	26627737	GBM cells	viability after 13 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.21950639897506008	[71]	[50,40]	3	hSpCas9	negative selection	962536
42722786	42722809	17	+	26627737	GBM cells	viability after 13 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.11390456022564543	[453]	[222,301]	1	hSpCas9	negative selection	962537
42727660	42727683	17	+	26627737	GBM cells	viability after 13 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.48325655646749055	[257]	[182,205]	6	hSpCas9	negative selection	962538
42712388	42712411	17	-	26627737	GBM cells	viability after 21 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.4431348342501591	[554]	[434,386]	4	hSpCas9	negative selection	1044848
42713333	42713356	17	+	26627737	GBM cells	viability after 21 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-0.10564813714318744	[408]	[217,195]	-1	hSpCas9	negative selection	1044849
42718466	42718489	17	+	26627737	GBM cells	viability after 21 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.8376386458069323	[138]	[47,36]	-6	hSpCas9	negative selection	1044850
42720366	42720389	17	-	26627737	GBM cells	viability after 21 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-2.0383934040438287	[71]	[8,9]	-9	hSpCas9	negative selection	1044851
42722786	42722809	17	+	26627737	GBM cells	viability after 21 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.24712803584276644	[453]	[298,286]	2	hSpCas9	negative selection	1044852
42727660	42727683	17	+	26627737	GBM cells	viability after 21 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.5986645491944743	[257]	[217,206]	6	hSpCas9	negative selection	1044853
42712388	42712411	17	-	26627737	RPE1	viability after 9 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.7948816869543944	[1839]	[283,393]	-5	hSpCas9	negative selection	1127163
42713333	42713356	17	+	26627737	RPE1	viability after 9 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	1.1772798799244684	[189]	[113,160]	7	hSpCas9	negative selection	1127164
42718466	42718489	17	+	26627737	RPE1	viability after 9 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.7721960016847896	[291]	[63,274]	5	hSpCas9	negative selection	1127165
42720366	42720389	17	-	26627737	RPE1	viability after 9 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.7550426223228448	[109]	[141,82]	8	hSpCas9	negative selection	1127166
42722786	42722809	17	+	26627737	RPE1	viability after 9 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.3075782119223671	[2780]	[320,1196]	-2	hSpCas9	negative selection	1127167
42727660	42727683	17	+	26627737	RPE1	viability after 9 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.603744708212129	[1031]	[233,184]	-4	hSpCas9	negative selection	1127168
42712388	42712411	17	-	26627737	RPE1	viability after 12 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.5137976659892618	[1839]	[268,427]	-4	hSpCas9	negative selection	1209478
42713333	42713356	17	+	26627737	RPE1	viability after 12 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	2.3912679537791384	[189]	[192,346]	9	hSpCas9	negative selection	1209479
42718466	42718489	17	+	26627737	RPE1	viability after 12 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.4427371066999126	[291]	[59,155]	3	hSpCas9	negative selection	1209480
42720366	42720389	17	-	26627737	RPE1	viability after 12 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.7286200753160115	[109]	[146,45]	8	hSpCas9	negative selection	1209481
42722786	42722809	17	+	26627737	RPE1	viability after 12 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.011229436998378972	[2780]	[225,1310]	0	hSpCas9	negative selection	1209482
42727660	42727683	17	+	26627737	RPE1	viability after 12 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.3920644287086527	[1031]	[220,200]	-3	hSpCas9	negative selection	1209483
42712388	42712411	17	-	26627737	RPE1	viability after 15 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.6159831726777445	[1839]	[304,372]	-4	hSpCas9	negative selection	1291793
42713333	42713356	17	+	26627737	RPE1	viability after 15 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	1.6555126442776618	[189]	[94,240]	8	hSpCas9	negative selection	1291794
42718466	42718489	17	+	26627737	RPE1	viability after 15 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.6871085812605241	[291]	[20,240]	4	hSpCas9	negative selection	1291795
42720366	42720389	17	-	26627737	RPE1	viability after 15 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.8644883306040239	[109]	[11,21]	-5	hSpCas9	negative selection	1291796
42722786	42722809	17	+	26627737	RPE1	viability after 15 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.4389587018063419	[2780]	[309,1795]	3	hSpCas9	negative selection	1291797
42727660	42727683	17	+	26627737	RPE1	viability after 15 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.8673870950976347	[1031]	[158,160]	-5	hSpCas9	negative selection	1291798
42712388	42712411	17	-	26627737	RPE1	viability after 18 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.14933707042544353	[1839]	[468,424]	-1	hSpCas9	negative selection	1374108
42713333	42713356	17	+	26627737	RPE1	viability after 18 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	2.655880238668332	[189]	[210,442]	9	hSpCas9	negative selection	1374109
42718466	42718489	17	+	26627737	RPE1	viability after 18 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.5128649793093741	[291]	[66,160]	3	hSpCas9	negative selection	1374110
42720366	42720389	17	-	26627737	RPE1	viability after 18 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.0223606261864886	[109]	[68,50]	6	hSpCas9	negative selection	1374111
42722786	42722809	17	+	26627737	RPE1	viability after 18 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.0872522290444118	[2780]	[416,2852]	6	hSpCas9	negative selection	1374112
42727660	42727683	17	+	26627737	RPE1	viability after 18 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-1.1291105671170039	[1031]	[136,116]	-6	hSpCas9	negative selection	1374113
42712388	42712411	17	-	26627737	HeLa	viability after 8 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.7846212851168244	[491]	[329,356,407]	6	hSpCas9	negative selection	1456423
42713333	42713356	17	+	26627737	HeLa	viability after 8 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-0.7592411780915991	[521]	[160,194,57]	-6	hSpCas9	negative selection	1456424
42718466	42718489	17	+	26627737	HeLa	viability after 8 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.7602476925091166	[187]	[327,88,46]	6	hSpCas9	negative selection	1456425
42720366	42720389	17	-	26627737	HeLa	viability after 8 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-1.1385133769388291	[123]	[33,7,32]	-8	hSpCas9	negative selection	1456426
42722786	42722809	17	+	26627737	HeLa	viability after 8 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.18267173255065727	[614]	[502,113,154]	-2	hSpCas9	negative selection	1456427
42727660	42727683	17	+	26627737	HeLa	viability after 8 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	1.1292194267403528	[346]	[365,380,256]	8	hSpCas9	negative selection	1456428
42712388	42712411	17	-	26627737	HeLa	viability after 12 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.8514360573542457	[491]	[341,374,381]	6	hSpCas9	negative selection	1538738
42713333	42713356	17	+	26627737	HeLa	viability after 12 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.08604814662533489	[521]	[233,210,243]	0	hSpCas9	negative selection	1538739
42718466	42718489	17	+	26627737	HeLa	viability after 12 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.08768286961899308	[187]	[25,119,66]	0	hSpCas9	negative selection	1538740
42720366	42720389	17	-	26627737	HeLa	viability after 12 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.24643543241652477	[123]	[161,25,0]	2	hSpCas9	negative selection	1538741
42722786	42722809	17	+	26627737	HeLa	viability after 12 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.16744095399031717	[614]	[271,256,147]	-1	hSpCas9	negative selection	1538742
42727660	42727683	17	+	26627737	HeLa	viability after 12 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	1.060918257163692	[346]	[193,246,458]	7	hSpCas9	negative selection	1538743
42712388	42712411	17	-	26627737	HeLa	viability after 15 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.8478925464207514	[491]	[653,228,180]	6	hSpCas9	negative selection	1621053
42713333	42713356	17	+	26627737	HeLa	viability after 15 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.03830188217738295	[521]	[80,422,146]	0	hSpCas9	negative selection	1621054
42718466	42718489	17	+	26627737	HeLa	viability after 15 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.3537773591804425	[187]	[105,56,132]	3	hSpCas9	negative selection	1621055
42720366	42720389	17	-	26627737	HeLa	viability after 15 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-1.9295650945650906	[123]	[10,24,2]	-9	hSpCas9	negative selection	1621056
42722786	42722809	17	+	26627737	HeLa	viability after 15 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.40940856548056404	[614]	[150,297,568]	3	hSpCas9	negative selection	1621057
42727660	42727683	17	+	26627737	HeLa	viability after 15 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.9810597232144507	[346]	[198,281,362]	7	hSpCas9	negative selection	1621058
42712388	42712411	17	-	26627737	HeLa	viability after 18 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.7781188542388662	[491]	[402,192,180]	6	hSpCas9	negative selection	1703368
42713333	42713356	17	+	26627737	HeLa	viability after 18 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.04321414975440008	[521]	[55,349,146]	0	hSpCas9	negative selection	1703369
42718466	42718489	17	+	26627737	HeLa	viability after 18 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.36374872033487415	[187]	[70,48,132]	3	hSpCas9	negative selection	1703370
42720366	42720389	17	-	26627737	HeLa	viability after 18 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-1.7479075094808003	[123]	[8,22,2]	-9	hSpCas9	negative selection	1703371
42722786	42722809	17	+	26627737	HeLa	viability after 18 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.4015416867232465	[614]	[99,243,568]	3	hSpCas9	negative selection	1703372
42727660	42727683	17	+	26627737	HeLa	viability after 18 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.9657507624214239	[346]	[132,226,362]	7	hSpCas9	negative selection	1703373
42712388	42712411	17	-	26627737	HCT116	viability after 6 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	1.4452396559165288	[936]	[355,425]	7	hSpCas9	negative selection	1785683
42713333	42713356	17	+	26627737	HCT116	viability after 6 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.823919046834005	[800]	[229,218]	4	hSpCas9	negative selection	1785684
42718466	42718489	17	+	26627737	HCT116	viability after 6 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-2.6615554792467844	[506]	[29,2]	-9	hSpCas9	negative selection	1785685
42720366	42720389	17	-	26627737	HCT116	viability after 6 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.672110849468353	[126]	[42,74]	8	hSpCas9	negative selection	1785686
42722786	42722809	17	+	26627737	HCT116	viability after 6 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.36830573004928213	[878]	[334,91]	2	hSpCas9	negative selection	1785687
42727660	42727683	17	+	26627737	HCT116	viability after 6 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.6223927362719095	[985]	[382,158]	3	hSpCas9	negative selection	1785688
42712388	42712411	17	-	26627737	HCT116	viability after 8 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.2996906592973003	[556]	[360,389,381]	3	hSpCas9	negative selection	1867998
42713333	42713356	17	+	26627737	HCT116	viability after 8 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.5633655497746424	[309]	[341,175,240]	5	hSpCas9	negative selection	1867999
42718466	42718489	17	+	26627737	HCT116	viability after 8 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.14162119266812145	[204]	[95,125,150]	1	hSpCas9	negative selection	1868000
42720366	42720389	17	-	26627737	HCT116	viability after 8 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.6078705180649784	[79]	[33,34,17]	-6	hSpCas9	negative selection	1868001
42722786	42722809	17	+	26627737	HCT116	viability after 8 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.0150097112990435	[275]	[369,314,238]	8	hSpCas9	negative selection	1868002
42727660	42727683	17	+	26627737	HCT116	viability after 8 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	2.615384509019851	[65]	[233,230,203]	9	hSpCas9	negative selection	1868003
42712388	42712411	17	-	26627737	HCT116	viability after 9 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.4947299338137974	[936]	[251,431]	3	hSpCas9	negative selection	1950313
42713333	42713356	17	+	26627737	HCT116	viability after 9 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	1.3962301452445471	[800]	[548,573]	8	hSpCas9	negative selection	1950314
42718466	42718489	17	+	26627737	HCT116	viability after 9 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.793618124299972	[506]	[38,108]	-5	hSpCas9	negative selection	1950315
42720366	42720389	17	-	26627737	HCT116	viability after 9 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.7415361082194596	[126]	[18,187]	9	hSpCas9	negative selection	1950316
42722786	42722809	17	+	26627737	HCT116	viability after 9 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.157105133039212	[878]	[795,307]	7	hSpCas9	negative selection	1950317
42727660	42727683	17	+	26627737	HCT116	viability after 9 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-1.2187805777924339	[985]	[173,64]	-7	hSpCas9	negative selection	1950318
42712388	42712411	17	-	26627737	HCT116	viability after 12 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.05067467150751814	[556]	[258,367,287]	0	hSpCas9	negative selection	2032628
42713333	42713356	17	+	26627737	HCT116	viability after 12 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.8222545881099472	[309]	[190,382,300]	7	hSpCas9	negative selection	2032629
42718466	42718489	17	+	26627737	HCT116	viability after 12 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.43101660545607245	[204]	[102,50,82]	-4	hSpCas9	negative selection	2032630
42720366	42720389	17	-	26627737	HCT116	viability after 12 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.22751252879746686	[79]	[4,58,46]	-2	hSpCas9	negative selection	2032631
42722786	42722809	17	+	26627737	HCT116	viability after 12 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.7396248615802089	[275]	[154,397,184]	6	hSpCas9	negative selection	2032632
42727660	42727683	17	+	26627737	HCT116	viability after 12 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	2.7933666704784343	[65]	[285,225,204]	9	hSpCas9	negative selection	2032633
42712388	42712411	17	-	26627737	HCT116	viability after 15 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.12010963037472844	[556]	[530,329,205]	1	hSpCas9	negative selection	2114943
42713333	42713356	17	+	26627737	HCT116	viability after 15 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.08551104068922238	[309]	[231,237,102]	0	hSpCas9	negative selection	2114944
42718466	42718489	17	+	26627737	HCT116	viability after 15 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.7727594295700552	[204]	[116,61,33]	-7	hSpCas9	negative selection	2114945
42720366	42720389	17	-	26627737	HCT116	viability after 15 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.14171760863377103	[79]	[35,25,61]	-1	hSpCas9	negative selection	2114946
42722786	42722809	17	+	26627737	HCT116	viability after 15 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.9774258710793414	[275]	[126,329,454]	8	hSpCas9	negative selection	2114947
42727660	42727683	17	+	26627737	HCT116	viability after 15 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	2.819198166980793	[65]	[321,205,280]	9	hSpCas9	negative selection	2114948
42712388	42712411	17	-	26627737	HCT116	viability after 18 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.37659624986342677	[556]	[293,173,153]	-3	hSpCas9	negative selection	2197258
42713333	42713356	17	+	26627737	HCT116	viability after 18 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.40101893098576863	[309]	[189,206,195]	3	hSpCas9	negative selection	2197259
42718466	42718489	17	+	26627737	HCT116	viability after 18 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.3689450562857344	[204]	[34,74,0]	-8	hSpCas9	negative selection	2197260
42720366	42720389	17	-	26627737	HCT116	viability after 18 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.22455281080920808	[79]	[27,39,68]	2	hSpCas9	negative selection	2197261
42722786	42722809	17	+	26627737	HCT116	viability after 18 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.1918240413162944	[275]	[90,404,416]	8	hSpCas9	negative selection	2197262
42727660	42727683	17	+	26627737	HCT116	viability after 18 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	2.5672371943710517	[65]	[203,142,224]	9	hSpCas9	negative selection	2197263
42727660	42727683	17	+	24336569	HL60	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.2203292998370561	[582]	[1058]	-2	hSpCas9	negative selection	2263688
42727694	42727717	17	+	24336569	HL60	viability	GCTTCTTCCATTCTTCATTGAGG	EZH1	ENSG00000108799	-0.2707888202796809	[247]	[434]	-2	hSpCas9	negative selection	2263689
42727700	42727723	17	+	24336569	HL60	viability	TCCATTCTTCATTGAGGATCTGG	EZH1	ENSG00000108799	0.5269573729162487	[243]	[743]	5	hSpCas9	negative selection	2263690
42727751	42727774	17	-	24336569	HL60	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.3338315814108342	[538]	[904]	-3	hSpCas9	negative selection	2263691
42728824	42728847	17	-	24336569	HL60	viability	TCAGGCAAATATGGGTGCAAAGG	EZH1	ENSG00000108799	0.7238242188107693	[498]	[1743]	6	hSpCas9	negative selection	2263692
42728832	42728855	17	-	24336569	HL60	viability	AAACGGCTTCAGGCAAATATGGG	EZH1	ENSG00000108799	0.5884715894050618	[488]	[1555]	5	hSpCas9	negative selection	2263693
42728842	42728865	17	-	24336569	HL60	viability	TCGACAACTTAAACGGCTTCAGG	EZH1	ENSG00000108799	-0.6460151413270925	[385]	[521]	-5	hSpCas9	negative selection	2263694
42728849	42728872	17	-	24336569	HL60	viability	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	1.3049315281366267	[371]	[1944]	8	hSpCas9	negative selection	2263695
42728894	42728917	17	+	24336569	HL60	viability	TTTCCAGTAAGTGATACATTTGG	EZH1	ENSG00000108799	-0.6262202789550324	[344]	[472]	-5	hSpCas9	negative selection	2263696
42728901	42728924	17	+	24336569	HL60	viability	TAAGTGATACATTTGGAGGTAGG	EZH1	ENSG00000108799	0.5748371818125221	[433]	[1367]	5	hSpCas9	negative selection	2263697
42727660	42727683	17	+	24336569	KBM7	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.38419049027740076	[422]	[883]	-3	hSpCas9	negative selection	2330865
42727694	42727717	17	+	24336569	KBM7	viability	GCTTCTTCCATTCTTCATTGAGG	EZH1	ENSG00000108799	0.07726231173470288	[195]	[563]	0	hSpCas9	negative selection	2330866
42727700	42727723	17	+	24336569	KBM7	viability	TCCATTCTTCATTGAGGATCTGG	EZH1	ENSG00000108799	0.454055673608141	[329]	[1232]	4	hSpCas9	negative selection	2330867
42727751	42727774	17	-	24336569	KBM7	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.04173240925003116	[373]	[990]	0	hSpCas9	negative selection	2330868
42728824	42728847	17	-	24336569	KBM7	viability	TCAGGCAAATATGGGTGCAAAGG	EZH1	ENSG00000108799	0.9124360830874578	[470]	[2417]	7	hSpCas9	negative selection	2330869
42728832	42728855	17	-	24336569	KBM7	viability	AAACGGCTTCAGGCAAATATGGG	EZH1	ENSG00000108799	0.5566577963375883	[509]	[2045]	5	hSpCas9	negative selection	2330870
42728842	42728865	17	-	24336569	KBM7	viability	TCGACAACTTAAACGGCTTCAGG	EZH1	ENSG00000108799	0.8332299110128873	[120]	[587]	7	hSpCas9	negative selection	2330871
42728849	42728872	17	-	24336569	KBM7	viability	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	1.3340585554003468	[282]	[1945]	9	hSpCas9	negative selection	2330872
42728894	42728917	17	+	24336569	KBM7	viability	TTTCCAGTAAGTGATACATTTGG	EZH1	ENSG00000108799	-0.4917790004594174	[463]	[899]	-4	hSpCas9	negative selection	2330873
42728901	42728924	17	+	24336569	KBM7	viability	TAAGTGATACATTTGGAGGTAGG	EZH1	ENSG00000108799	0.2254746337971305	[269]	[860]	2	hSpCas9	negative selection	2330874
42743446	42743469	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCGTGCCAGG	EZH1	ENSG00000108799	-0.779191386983709	[52,249]	[14,23]	-4	dCas9-VP64	positive selection	2445723
42720876	42720899	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGATCACCTGAGGTCTGG	EZH1	ENSG00000108799	8.572613315975907	[14,15]	[366,2389]	9	dCas9-VP64	positive selection	2455619
42733874	42733897	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCAGTGAGCCGAGACAG	EZH1	ENSG00000108799	0.6330757747468561	[50,16]	[8,13]	2	dCas9-VP64	positive selection	2476896
42743446	42743469	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCGTGCCAGG	EZH1	ENSG00000108799	0.389783500937638	[291,598]	[109,262]	3	dCas9-VP64	positive selection	2540978
42720876	42720899	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGATCACCTGAGGTCTGG	EZH1	ENSG00000108799	1.5525228181942226	[88,74]	[56,98]	8	dCas9-VP64	positive selection	2550874
42733874	42733897	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCAGTGAGCCGAGACAG	EZH1	ENSG00000108799	0.34517561365305327	[29,16]	[7,9]	2	dCas9-VP64	positive selection	2572151
42728842	42728865	17	-	27260157	DLD1	viability	TCGACAACTTAAACGGCTTCAGG	EZH1	ENSG00000108799	-0.51905405001634	[]	[]	-4	hSpCas9	negative selection	2577968
42713321	42713344	17	-	27260157	DLD1	viability	GCTCTGGTCGTCGCCGGAGAAGG	EZH1	ENSG00000108799	0.0484822028088844	[]	[]	3	hSpCas9	negative selection	2578344
42718466	42718489	17	+	27260157	DLD1	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.5395674304256	[]	[]	-8	hSpCas9	negative selection	2579243
42718549	42718572	17	-	27260157	DLD1	viability	CAGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.660189158767999	[]	[]	8	hSpCas9	negative selection	2580952
42728832	42728855	17	-	27260157	DLD1	viability	AAACGGCTTCAGGCAAATATGGG	EZH1	ENSG00000108799	0.154231808832455	[]	[]	3	hSpCas9	negative selection	2581622
42724382	42724405	17	+	27260157	DLD1	viability	TATGTTGGCTTGCAAATCCCGGG	EZH1	ENSG00000108799	-0.955755981062517	[]	[]	-7	hSpCas9	negative selection	2582309
42718518	42718541	17	+	27260157	DLD1	viability	TTGCTCCCGCTGCACAGACTTGG	EZH1	ENSG00000108799	0.111485606644759	[]	[]	3	hSpCas9	negative selection	2585142
42727660	42727683	17	+	27260157	DLD1	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.674930962217816	[]	[]	-5	hSpCas9	negative selection	2586334
42728824	42728847	17	-	27260157	DLD1	viability	TCAGGCAAATATGGGTGCAAAGG	EZH1	ENSG00000108799	-0.163350118690702	[]	[]	-1	hSpCas9	negative selection	2604176
42719102	42719125	17	+	27260157	DLD1	viability	TACCTCTCCTTCATGTCATCTGG	EZH1	ENSG00000108799	-0.41845732155241	[]	[]	-3	hSpCas9	negative selection	2607485
42727751	42727774	17	-	27260157	DLD1	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.273953665984863	[]	[]	-2	hSpCas9	negative selection	2607819
42712410	42712433	17	+	27260157	DLD1	viability	GCTTCCACTACGCAGAGTTGAGG	EZH1	ENSG00000108799	0.71666661047888	[]	[]	8	hSpCas9	negative selection	2609611
42727700	42727723	17	+	27260157	DLD1	viability	TCCATTCTTCATTGAGGATCTGG	EZH1	ENSG00000108799	-0.812322711376427	[]	[]	-6	hSpCas9	negative selection	2613642
42713327	42713350	17	+	27260157	DLD1	viability	CCGGCGACGACCAGAGCACTTGG	EZH1	ENSG00000108799	0.690261819713389	[]	[]	8	hSpCas9	negative selection	2614618
42727694	42727717	17	+	27260157	DLD1	viability	GCTTCTTCCATTCTTCATTGAGG	EZH1	ENSG00000108799	0.0306011988568999	[]	[]	0	hSpCas9	negative selection	2617095
42713224	42713247	17	-	27260157	DLD1	viability	CAGGGACACAGGCAATGACTGGG	EZH1	ENSG00000108799	-0.479000102171659	[]	[]	-4	hSpCas9	negative selection	2623590
42719128	42719151	17	+	27260157	DLD1	viability	ACCATTCTCAGGGAACATTGAGG	EZH1	ENSG00000108799	-0.50291521637545	[]	[]	-4	hSpCas9	negative selection	2643262
42728901	42728924	17	+	27260157	DLD1	viability	TAAGTGATACATTTGGAGGTAGG	EZH1	ENSG00000108799	0.713420940550047	[]	[]	8	hSpCas9	negative selection	2643886
42728894	42728917	17	+	27260157	DLD1	viability	TTTCCAGTAAGTGATACATTTGG	EZH1	ENSG00000108799	0.888614337657598	[]	[]	9	hSpCas9	negative selection	2647820
42728849	42728872	17	-	27260157	DLD1	viability	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	-0.764177682894122	[]	[]	-5	hSpCas9	negative selection	2648581
42728842	42728865	17	-	27260157	HT1080	viability	TCGACAACTTAAACGGCTTCAGG	EZH1	ENSG00000108799	-0.603674142761309	[]	[]	-8	hSpCas9	negative selection	2654098
42713321	42713344	17	-	27260157	HT1080	viability	GCTCTGGTCGTCGCCGGAGAAGG	EZH1	ENSG00000108799	-0.0134056182662675	[]	[]	0	hSpCas9	negative selection	2654474
42718466	42718489	17	+	27260157	HT1080	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.0689955723821	[]	[]	-8	hSpCas9	negative selection	2655373
42718549	42718572	17	-	27260157	HT1080	viability	CAGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.132433074034671	[]	[]	1	hSpCas9	negative selection	2657082
42728832	42728855	17	-	27260157	HT1080	viability	AAACGGCTTCAGGCAAATATGGG	EZH1	ENSG00000108799	-0.48733380871866	[]	[]	-7	hSpCas9	negative selection	2657752
42724382	42724405	17	+	27260157	HT1080	viability	TATGTTGGCTTGCAAATCCCGGG	EZH1	ENSG00000108799	-1.19573087601134	[]	[]	-8	hSpCas9	negative selection	2658439
42718518	42718541	17	+	27260157	HT1080	viability	TTGCTCCCGCTGCACAGACTTGG	EZH1	ENSG00000108799	1.16671063137381	[]	[]	8	hSpCas9	negative selection	2661272
42727660	42727683	17	+	27260157	HT1080	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.0535030676529216	[]	[]	0	hSpCas9	negative selection	2662464
42728824	42728847	17	-	27260157	HT1080	viability	TCAGGCAAATATGGGTGCAAAGG	EZH1	ENSG00000108799	-0.17260684353386	[]	[]	0	hSpCas9	negative selection	2680306
42719102	42719125	17	+	27260157	HT1080	viability	TACCTCTCCTTCATGTCATCTGG	EZH1	ENSG00000108799	-0.358042261216754	[]	[]	-7	hSpCas9	negative selection	2683615
42727751	42727774	17	-	27260157	HT1080	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-1.2711855607719	[]	[]	-9	hSpCas9	negative selection	2683949
42712410	42712433	17	+	27260157	HT1080	viability	GCTTCCACTACGCAGAGTTGAGG	EZH1	ENSG00000108799	0.230812527812921	[]	[]	2	hSpCas9	negative selection	2685741
42727700	42727723	17	+	27260157	HT1080	viability	TCCATTCTTCATTGAGGATCTGG	EZH1	ENSG00000108799	-0.419771584937413	[]	[]	-7	hSpCas9	negative selection	2689772
42713327	42713350	17	+	27260157	HT1080	viability	CCGGCGACGACCAGAGCACTTGG	EZH1	ENSG00000108799	0.783284854886996	[]	[]	6	hSpCas9	negative selection	2690748
42727694	42727717	17	+	27260157	HT1080	viability	GCTTCTTCCATTCTTCATTGAGG	EZH1	ENSG00000108799	-0.122348085946867	[]	[]	0	hSpCas9	negative selection	2693225
42713224	42713247	17	-	27260157	HT1080	viability	CAGGGACACAGGCAATGACTGGG	EZH1	ENSG00000108799	-0.724715244972778	[]	[]	-8	hSpCas9	negative selection	2699720
42719128	42719151	17	+	27260157	HT1080	viability	ACCATTCTCAGGGAACATTGAGG	EZH1	ENSG00000108799	0.0253079037119689	[]	[]	0	hSpCas9	negative selection	2719392
42728901	42728924	17	+	27260157	HT1080	viability	TAAGTGATACATTTGGAGGTAGG	EZH1	ENSG00000108799	-0.427859215105329	[]	[]	-7	hSpCas9	negative selection	2720016
42728894	42728917	17	+	27260157	HT1080	viability	TTTCCAGTAAGTGATACATTTGG	EZH1	ENSG00000108799	0.534055655819485	[]	[]	5	hSpCas9	negative selection	2723950
42728849	42728872	17	-	27260157	HT1080	viability	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	0.0329715765868076	[]	[]	0	hSpCas9	negative selection	2724711
42728842	42728865	17	-	27260157	MKN45	viability	TCGACAACTTAAACGGCTTCAGG	EZH1	ENSG00000108799	-0.0639158437448714	[]	[]	0	hSpCas9	negative selection	2730228
42713321	42713344	17	-	27260157	MKN45	viability	GCTCTGGTCGTCGCCGGAGAAGG	EZH1	ENSG00000108799	-0.766023502157499	[]	[]	-7	hSpCas9	negative selection	2730604
42718466	42718489	17	+	27260157	MKN45	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-2.83727173621268	[]	[]	-9	hSpCas9	negative selection	2731503
42718549	42718572	17	-	27260157	MKN45	viability	CAGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.657177077428515	[]	[]	7	hSpCas9	negative selection	2733212
42728832	42728855	17	-	27260157	MKN45	viability	AAACGGCTTCAGGCAAATATGGG	EZH1	ENSG00000108799	-0.0724699595547864	[]	[]	0	hSpCas9	negative selection	2733882
42724382	42724405	17	+	27260157	MKN45	viability	TATGTTGGCTTGCAAATCCCGGG	EZH1	ENSG00000108799	-1.76797039029331	[]	[]	-9	hSpCas9	negative selection	2734569
42718518	42718541	17	+	27260157	MKN45	viability	TTGCTCCCGCTGCACAGACTTGG	EZH1	ENSG00000108799	0.199851302168162	[]	[]	5	hSpCas9	negative selection	2737402
42727660	42727683	17	+	27260157	MKN45	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.446765090072873	[]	[]	-6	hSpCas9	negative selection	2738594
42728824	42728847	17	-	27260157	MKN45	viability	TCAGGCAAATATGGGTGCAAAGG	EZH1	ENSG00000108799	-0.604501417264412	[]	[]	-6	hSpCas9	negative selection	2756436
42719102	42719125	17	+	27260157	MKN45	viability	TACCTCTCCTTCATGTCATCTGG	EZH1	ENSG00000108799	0.430189229963331	[]	[]	6	hSpCas9	negative selection	2759745
42727751	42727774	17	-	27260157	MKN45	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-1.48468015128523	[]	[]	-8	hSpCas9	negative selection	2760079
42712410	42712433	17	+	27260157	MKN45	viability	GCTTCCACTACGCAGAGTTGAGG	EZH1	ENSG00000108799	0.891943245302316	[]	[]	8	hSpCas9	negative selection	2761871
42727700	42727723	17	+	27260157	MKN45	viability	TCCATTCTTCATTGAGGATCTGG	EZH1	ENSG00000108799	-0.143707428122042	[]	[]	0	hSpCas9	negative selection	2765902
42713327	42713350	17	+	27260157	MKN45	viability	CCGGCGACGACCAGAGCACTTGG	EZH1	ENSG00000108799	0.631510115451497	[]	[]	7	hSpCas9	negative selection	2766878
42727694	42727717	17	+	27260157	MKN45	viability	GCTTCTTCCATTCTTCATTGAGG	EZH1	ENSG00000108799	-0.511109792803221	[]	[]	-6	hSpCas9	negative selection	2769355
42713224	42713247	17	-	27260157	MKN45	viability	CAGGGACACAGGCAATGACTGGG	EZH1	ENSG00000108799	-0.569025537971222	[]	[]	-6	hSpCas9	negative selection	2775850
42719128	42719151	17	+	27260157	MKN45	viability	ACCATTCTCAGGGAACATTGAGG	EZH1	ENSG00000108799	-1.01912074371519	[]	[]	-8	hSpCas9	negative selection	2795522
42728901	42728924	17	+	27260157	MKN45	viability	TAAGTGATACATTTGGAGGTAGG	EZH1	ENSG00000108799	-0.370806355854297	[]	[]	-1	hSpCas9	negative selection	2796146
42728894	42728917	17	+	27260157	MKN45	viability	TTTCCAGTAAGTGATACATTTGG	EZH1	ENSG00000108799	-0.456167550284721	[]	[]	-6	hSpCas9	negative selection	2800080
42728849	42728872	17	-	27260157	MKN45	viability	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	-0.334893912767032	[]	[]	-1	hSpCas9	negative selection	2800841
42728842	42728865	17	-	27260157	RKO	viability	TCGACAACTTAAACGGCTTCAGG	EZH1	ENSG00000108799	0.231924123794511	[]	[]	1	hSpCas9	negative selection	2806358
42713321	42713344	17	-	27260157	RKO	viability	GCTCTGGTCGTCGCCGGAGAAGG	EZH1	ENSG00000108799	-0.332571635951234	[]	[]	-6	hSpCas9	negative selection	2806734
42718466	42718489	17	+	27260157	RKO	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.38052909148265	[]	[]	-8	hSpCas9	negative selection	2807633
42718549	42718572	17	-	27260157	RKO	viability	CAGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.385475838720357	[]	[]	2	hSpCas9	negative selection	2809342
42728832	42728855	17	-	27260157	RKO	viability	AAACGGCTTCAGGCAAATATGGG	EZH1	ENSG00000108799	-0.277418190300593	[]	[]	-1	hSpCas9	negative selection	2810012
42724382	42724405	17	+	27260157	RKO	viability	TATGTTGGCTTGCAAATCCCGGG	EZH1	ENSG00000108799	-0.745151406433523	[]	[]	-7	hSpCas9	negative selection	2810699
42718518	42718541	17	+	27260157	RKO	viability	TTGCTCCCGCTGCACAGACTTGG	EZH1	ENSG00000108799	0.694950745157868	[]	[]	8	hSpCas9	negative selection	2813532
42727660	42727683	17	+	27260157	RKO	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.232378006614868	[]	[]	1	hSpCas9	negative selection	2814724
42728824	42728847	17	-	27260157	RKO	viability	TCAGGCAAATATGGGTGCAAAGG	EZH1	ENSG00000108799	-0.28325737651008	[]	[]	-5	hSpCas9	negative selection	2832566
42719102	42719125	17	+	27260157	RKO	viability	TACCTCTCCTTCATGTCATCTGG	EZH1	ENSG00000108799	3.11985397321285	[]	[]	9	hSpCas9	negative selection	2835875
42727751	42727774	17	-	27260157	RKO	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.57319746241697	[]	[]	-7	hSpCas9	negative selection	2836209
42712410	42712433	17	+	27260157	RKO	viability	GCTTCCACTACGCAGAGTTGAGG	EZH1	ENSG00000108799	-0.223837509079262	[]	[]	-1	hSpCas9	negative selection	2838001
42727700	42727723	17	+	27260157	RKO	viability	TCCATTCTTCATTGAGGATCTGG	EZH1	ENSG00000108799	-0.902325777180765	[]	[]	-8	hSpCas9	negative selection	2842032
42713327	42713350	17	+	27260157	RKO	viability	CCGGCGACGACCAGAGCACTTGG	EZH1	ENSG00000108799	0.394045936489452	[]	[]	2	hSpCas9	negative selection	2843008
42727694	42727717	17	+	27260157	RKO	viability	GCTTCTTCCATTCTTCATTGAGG	EZH1	ENSG00000108799	0.0238830244073128	[]	[]	0	hSpCas9	negative selection	2845485
42713224	42713247	17	-	27260157	RKO	viability	CAGGGACACAGGCAATGACTGGG	EZH1	ENSG00000108799	-0.520573768214492	[]	[]	-6	hSpCas9	negative selection	2851980
42719128	42719151	17	+	27260157	RKO	viability	ACCATTCTCAGGGAACATTGAGG	EZH1	ENSG00000108799	-0.152048845399828	[]	[]	0	hSpCas9	negative selection	2871652
42728901	42728924	17	+	27260157	RKO	viability	TAAGTGATACATTTGGAGGTAGG	EZH1	ENSG00000108799	-0.183385512614542	[]	[]	-1	hSpCas9	negative selection	2872276
42728894	42728917	17	+	27260157	RKO	viability	TTTCCAGTAAGTGATACATTTGG	EZH1	ENSG00000108799	-0.210251663012624	[]	[]	-1	hSpCas9	negative selection	2876210
42728849	42728872	17	-	27260157	RKO	viability	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	-0.176751491629697	[]	[]	-1	hSpCas9	negative selection	2876971
42728842	42728865	17	-	27260157	SF268	viability	TCGACAACTTAAACGGCTTCAGG	EZH1	ENSG00000108799	0.167926562243575	[]	[]	0	hSpCas9	negative selection	2882488
42713321	42713344	17	-	27260157	SF268	viability	GCTCTGGTCGTCGCCGGAGAAGG	EZH1	ENSG00000108799	-0.595873367821565	[]	[]	-4	hSpCas9	negative selection	2882864
42718466	42718489	17	+	27260157	SF268	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-2.18521741276692	[]	[]	-9	hSpCas9	negative selection	2883763
42718549	42718572	17	-	27260157	SF268	viability	CAGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.0419426482902307	[]	[]	0	hSpCas9	negative selection	2885472
42728832	42728855	17	-	27260157	SF268	viability	AAACGGCTTCAGGCAAATATGGG	EZH1	ENSG00000108799	-0.065478117927107	[]	[]	0	hSpCas9	negative selection	2886142
42724382	42724405	17	+	27260157	SF268	viability	TATGTTGGCTTGCAAATCCCGGG	EZH1	ENSG00000108799	-1.38969973197969	[]	[]	-8	hSpCas9	negative selection	2886829
42718518	42718541	17	+	27260157	SF268	viability	TTGCTCCCGCTGCACAGACTTGG	EZH1	ENSG00000108799	-0.127313064397841	[]	[]	-1	hSpCas9	negative selection	2889662
42727660	42727683	17	+	27260157	SF268	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.280474654455971	[]	[]	4	hSpCas9	negative selection	2890854
42728824	42728847	17	-	27260157	SF268	viability	TCAGGCAAATATGGGTGCAAAGG	EZH1	ENSG00000108799	-0.895819726037487	[]	[]	-6	hSpCas9	negative selection	2908696
42719102	42719125	17	+	27260157	SF268	viability	TACCTCTCCTTCATGTCATCTGG	EZH1	ENSG00000108799	0.477603543325837	[]	[]	7	hSpCas9	negative selection	2912005
42727751	42727774	17	-	27260157	SF268	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.854563657516044	[]	[]	-6	hSpCas9	negative selection	2912339
42712410	42712433	17	+	27260157	SF268	viability	GCTTCCACTACGCAGAGTTGAGG	EZH1	ENSG00000108799	0.305369187585825	[]	[]	4	hSpCas9	negative selection	2914131
42727700	42727723	17	+	27260157	SF268	viability	TCCATTCTTCATTGAGGATCTGG	EZH1	ENSG00000108799	0.0465909744634697	[]	[]	0	hSpCas9	negative selection	2918162
42713327	42713350	17	+	27260157	SF268	viability	CCGGCGACGACCAGAGCACTTGG	EZH1	ENSG00000108799	0.81815820241608	[]	[]	8	hSpCas9	negative selection	2919138
42727694	42727717	17	+	27260157	SF268	viability	GCTTCTTCCATTCTTCATTGAGG	EZH1	ENSG00000108799	-0.256964636992958	[]	[]	-2	hSpCas9	negative selection	2921615
42713224	42713247	17	-	27260157	SF268	viability	CAGGGACACAGGCAATGACTGGG	EZH1	ENSG00000108799	-1.13179659412889	[]	[]	-7	hSpCas9	negative selection	2928110
42719128	42719151	17	+	27260157	SF268	viability	ACCATTCTCAGGGAACATTGAGG	EZH1	ENSG00000108799	-0.794952340100278	[]	[]	-6	hSpCas9	negative selection	2947782
42728901	42728924	17	+	27260157	SF268	viability	TAAGTGATACATTTGGAGGTAGG	EZH1	ENSG00000108799	-0.0248353305008762	[]	[]	0	hSpCas9	negative selection	2948406
42728894	42728917	17	+	27260157	SF268	viability	TTTCCAGTAAGTGATACATTTGG	EZH1	ENSG00000108799	0.210426960080493	[]	[]	3	hSpCas9	negative selection	2952340
42728849	42728872	17	-	27260157	SF268	viability	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	0.304793554991799	[]	[]	4	hSpCas9	negative selection	2953101
42718524	42718547	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.22614566759543103	[3,3]	[4,2]	5	hSpCas9	positive selection	2986742
42728898	42728921	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGTAAGTGATACATTTGGAGG	EZH1	ENSG00000108799	0.17318837411003957	[3,3]	[4,2]	3	hSpCas9	positive selection	2986743
42718037	42718060	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	0.6170657630162919	[2,3]	[2,4]	9	hSpCas9	positive selection	2986744
42728849	42728872	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	0.13694967216624776	[4,4]	[5,3]	3	hSpCas9	positive selection	2986745
42718524	42718547	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.23656389484998874	[3,3]	[2,0]	-3	hSpCas9	positive selection	3054600
42728898	42728921	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGTAAGTGATACATTTGGAGG	EZH1	ENSG00000108799	0.17440626644933827	[3,3]	[4,1]	3	hSpCas9	positive selection	3054601
42718037	42718060	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	0.16472506839766463	[2,2]	[1,2]	3	hSpCas9	positive selection	3054602
42728849	42728872	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	0.19217853062190104	[4,4]	[5,2]	3	hSpCas9	positive selection	3054603
42727660	42727683		+	24336571	A375	resistance to PLX after 7 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.02384514332154574	[10,15]	[12,12]	0	hSpCas9	positive selection	3112903
42724304	42724327		-	24336571	A375	resistance to PLX after 7 days	CCCTCTCCAACAGAACTTTATGG	EZH1	ENSG00000108799	-0.2305025155853657	[10,11]	[10,7]	-7	hSpCas9	positive selection	3112905
42727751	42727774		-	24336571	A375	resistance to PLX after 7 days	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.01675019472055511	[14,15]	[15,14]	0	hSpCas9	positive selection	3112906
42727660	42727683		+	24336571	A375	resistance to PLX after 14 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	1.7773934138356515	[9,9]	[14,17]	9	hSpCas9	positive selection	3170696
42724304	42724327		-	24336571	A375	resistance to PLX after 14 days	CCCTCTCCAACAGAACTTTATGG	EZH1	ENSG00000108799	-0.9323284543398376	[11,12]	[1,2]	-9	hSpCas9	positive selection	3170698
42727751	42727774		-	24336571	A375	resistance to PLX after 14 days	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.16338902632090807	[14,10]	[5,6]	1	hSpCas9	positive selection	3170699
42727660	42727683		+	24336571	A375	viability after 7 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.012141831281783207	[13]	[10,15]	0	hSpCas9	negative selection	3228489
42724304	42724327		-	24336571	A375	viability after 7 days	CCCTCTCCAACAGAACTTTATGG	EZH1	ENSG00000108799	0.03015417032084039	[11]	[10,11]	0	hSpCas9	negative selection	3228491
42727751	42727774		-	24336571	A375	viability after 7 days	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.27600769327525887	[12]	[14,15]	4	hSpCas9	negative selection	3228492
42727660	42727683		+	24336571	A375	viability after 14 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.35443802358409837	[13]	[9,9]	-4	hSpCas9	negative selection	3286282
42724304	42724327		-	24336571	A375	viability after 14 days	CCCTCTCCAACAGAACTTTATGG	EZH1	ENSG00000108799	0.1673606678088735	[11]	[11,12]	2	hSpCas9	negative selection	3286284
42727751	42727774		-	24336571	A375	viability after 14 days	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.042393591111028535	[12]	[14,10]	0	hSpCas9	negative selection	3286285
42727660	42727683	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.15345561367388272	[145,128]	[0,0]	0	hSpCas9	positive selection	3348636
42722814	42722837	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.021654595415365883	[125,184]	[0,0]	0	hSpCas9	positive selection	3348637
42720369	42720392	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	-1.6963947495021763	[470,520]	[0,0]	-9	hSpCas9	positive selection	3348638
42720272	42720295	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	0.22390320990838475	[130,130]	[0,0]	1	hSpCas9	positive selection	3367841
42722786	42722809	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.43616074605349014	[206,206]	[0,0]	-3	hSpCas9	positive selection	3367842
42727751	42727774	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.6615370258287593	[241,241]	[0,0]	-4	hSpCas9	positive selection	3367843
42718524	42718547	17	-	26780180	HT29	viability (Avana library 4 designs)	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	1.98220561618738	[]	[]	7	hSpCas9	negative selection	3423577
42728897	42728920	17	+	26780180	HT29	viability (Avana library 4 designs)	CCAGTAAGTGATACATTTGGAGG	EZH1	ENSG00000108799	0.783024793486778	[]	[]	3	hSpCas9	negative selection	3423578
42718036	42718059	17	+	26780180	HT29	viability (Avana library 4 designs)	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	3.48268838683324	[]	[]	9	hSpCas9	negative selection	3423579
42728849	42728872	17	-	26780180	HT29	viability (Avana library 4 designs)	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	0.330090218636799	[]	[]	1	hSpCas9	negative selection	3423580
42728849	42728872	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	-1.9650455918865	[]	[]	-2	hSpCas9	negative selection	3504799
42728897	42728920	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGTAAGTGATACATTTGGAGG	EZH1	ENSG00000108799	-1.15687210586576	[]	[]	-1	hSpCas9	negative selection	3504800
42718036	42718059	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-2.8549993881699	[]	[]	-3	hSpCas9	negative selection	3504801
42718524	42718547	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.446239524740155	[]	[]	0	hSpCas9	negative selection	3504802
42720420	42720443	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	2.73956426980361	[]	[]	4	hSpCas9	negative selection	3504803
42720412	42720435	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACAGCATCACTAATCAGAACGG	EZH1	ENSG00000108799	-3.9275286799132	[]	[]	-4	hSpCas9	negative selection	3504804
42728849	42728872	17	-	26780180	A375	viability (Avana lentiGuide)	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	-6.6116145575237	[]	[]	-9	hSpCas9	negative selection	3613458
42728897	42728920	17	+	26780180	A375	viability (Avana lentiGuide)	CCAGTAAGTGATACATTTGGAGG	EZH1	ENSG00000108799	1.47406204075582	[]	[]	1	hSpCas9	negative selection	3613459
42718036	42718059	17	+	26780180	A375	viability (Avana lentiGuide)	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-4.16742638413383	[]	[]	-7	hSpCas9	negative selection	3613460
42718524	42718547	17	-	26780180	A375	viability (Avana lentiGuide)	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	1.13939638877942	[]	[]	1	hSpCas9	negative selection	3613461
42720420	42720443	17	+	26780180	A375	viability (Avana lentiGuide)	CACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	1.32599778977356	[]	[]	1	hSpCas9	negative selection	3613462
42720412	42720435	17	+	26780180	A375	viability (Avana lentiGuide)	AACAGCATCACTAATCAGAACGG	EZH1	ENSG00000108799	-3.91909553828807	[]	[]	-6	hSpCas9	negative selection	3613463
42728849	42728872	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	-0.1170325947331147	[6]	[5,5]	-2	hSpCas9	positive selection	3722117
42728897	42728920	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGTAAGTGATACATTTGGAGG	EZH1	ENSG00000108799	-0.40209654067328293	[5]	[5,2]	-5	hSpCas9	positive selection	3722118
42718036	42718059	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-0.5901992609996551	[5]	[3,2]	-7	hSpCas9	positive selection	3722119
42718524	42718547	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.0699197370146155	[4]	[5,3]	-1	hSpCas9	positive selection	3722120
42720420	42720443	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	-0.056865875404497904	[5]	[5,4]	-1	hSpCas9	positive selection	3722121
42720412	42720435	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACAGCATCACTAATCAGAACGG	EZH1	ENSG00000108799	-0.2164526562006803	[5]	[4,4]	-3	hSpCas9	positive selection	3722122
42728849	42728872	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCGACTTCGACAACTTAAACGG	EZH1	ENSG00000108799	0.29449821955223776	[6]	[7,6]	7	hSpCas9	positive selection	3830724
42728897	42728920	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGTAAGTGATACATTTGGAGG	EZH1	ENSG00000108799	-0.2713538168045713	[5]	[3,3]	-4	hSpCas9	positive selection	3830725
42718036	42718059	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-0.09662058854562236	[5]	[3,4]	-1	hSpCas9	positive selection	3830726
42718524	42718547	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.06518641896985704	[5]	[3,4]	-1	hSpCas9	positive selection	3830727
42720420	42720443	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.2666514170468929	[5]	[4,5]	7	hSpCas9	positive selection	3830728
42720412	42720435	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACAGCATCACTAATCAGAACGG	EZH1	ENSG00000108799	0.2589251876571425	[5]	[4,6]	7	hSpCas9	positive selection	3830729
42727660	42727683	17	+	26780180	A375	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	1.00822932510855	[]	[]	5	hSpCas9	negative selection	3938090
42720272	42720295	17	-	26780180	A375	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	0.983291316427006	[]	[]	4	hSpCas9	negative selection	3938091
42722814	42722837	17	-	26780180	A375	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.603999018185887	[]	[]	2	hSpCas9	negative selection	3938092
42720369	42720392	17	+	26780180	A375	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.259086641366798	[]	[]	0	hSpCas9	negative selection	3938093
42727751	42727774	17	-	26780180	A375	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.080515132793881	[]	[]	0	hSpCas9	negative selection	3938094
42722786	42722809	17	+	26780180	A375	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.22007488602228	[]	[]	6	hSpCas9	negative selection	3938095
42727660	42727683	17	+	26780180	HT29	viability (GeCKOv2 library)	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.846974857242481	[]	[]	3	hSpCas9	negative selection	4046056
42720272	42720295	17	-	26780180	HT29	viability (GeCKOv2 library)	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	0.959722260776589	[]	[]	4	hSpCas9	negative selection	4046057
42722814	42722837	17	-	26780180	HT29	viability (GeCKOv2 library)	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	1.043460598736	[]	[]	5	hSpCas9	negative selection	4046058
42720369	42720392	17	+	26780180	HT29	viability (GeCKOv2 library)	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.536574715690022	[]	[]	1	hSpCas9	negative selection	4046059
42727751	42727774	17	-	26780180	HT29	viability (GeCKOv2 library)	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.351745927546567	[]	[]	1	hSpCas9	negative selection	4046060
42722786	42722809	17	+	26780180	HT29	viability (GeCKOv2 library)	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.832501050371473	[]	[]	3	hSpCas9	negative selection	4046061
42727660	42727683	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.2202624816936007	[3]	[1,3]	5	hSpCas9	positive selection	4135659
42724304	42724327	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTCTCCAACAGAACTTTATGG	EZH1	ENSG00000108799	-0.602301304473281	[3]	[1,1]	-9	hSpCas9	positive selection	4135661
42727751	42727774	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.03747686158868707	[4]	[2,2]	-1	hSpCas9	positive selection	4135662
42727660	42727683	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	1.0873079532150565	[0]	[0,2,1,0]	7	hSpCas9	positive selection	4199681
42724304	42724327	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTCTCCAACAGAACTTTATGG	EZH1	ENSG00000108799	1.0377295987621968	[3]	[3,2,1,3]	7	hSpCas9	positive selection	4199683
42727751	42727774	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.24323841302564866	[3]	[1,0,1,0]	-4	hSpCas9	positive selection	4199684
42727660	42727683	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.09350963628402847	[3]	[3,2]	2	hSpCas9	positive selection	4269521
42722814	42722837	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.0860637248506966	[3]	[3,1]	1	hSpCas9	positive selection	4269522
42720369	42720392	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.2562785063633078	[4]	[4,3]	5	hSpCas9	positive selection	4269523
42720272	42720295	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.16736927402125235	[3]	[3,0]	-3	hSpCas9	positive selection	4333786
42722786	42722809	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.053499301156484186	[3]	[3,1]	-1	hSpCas9	positive selection	4333787
42727751	42727774	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.32255440633834664	[3]	[3,3]	6	hSpCas9	positive selection	4333788
42713327	42713349	17	-	27760321	OCIAML3	viability	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	0.04962468868507153	[1081,979]	[605,1130]	0	hSpCas9	negative selection	4398834
42718467	42718489	17	+	27760321	OCIAML3	viability	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.8196308665208656	[291,234]	[129,97]	-6	hSpCas9	negative selection	4398835
42718525	42718547	17	+	27760321	OCIAML3	viability	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.12436300330028605	[759,641]	[538,668]	1	hSpCas9	negative selection	4398836
42718549	42718571	17	-	27760321	OCIAML3	viability	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.0018044874037583813	[654,494]	[522,346]	0	hSpCas9	negative selection	4398837
42720421	42720443	17	+	27760321	OCIAML3	viability	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.41508591256627375	[390,303]	[371,343]	5	hSpCas9	negative selection	4398838
42713327	42713349	17	-	27760321	OCIAML2	viability	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.03891135339635832	[1081,979]	[758,879]	0	hSpCas9	negative selection	4482297
42718467	42718489	17	+	27760321	OCIAML2	viability	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.0596228480272567	[291,234]	[191,258]	0	hSpCas9	negative selection	4482298
42718525	42718547	17	+	27760321	OCIAML2	viability	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.2621343471028609	[759,641]	[671,684]	3	hSpCas9	negative selection	4482299
42718549	42718571	17	-	27760321	OCIAML2	viability	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.3481435743371203	[654,494]	[503,696]	5	hSpCas9	negative selection	4482300
42720421	42720443	17	+	27760321	OCIAML2	viability	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.672715369297923	[390,303]	[384,523]	8	hSpCas9	negative selection	4482301
42713327	42713349	17	-	27760321	MV411	viability	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	0.29918527627587177	[1081,979]	[951,662]	2	hSpCas9	negative selection	4565760
42718467	42718489	17	+	27760321	MV411	viability	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.7967934003878125	[291,234]	[8,110]	-8	hSpCas9	negative selection	4565761
42718525	42718547	17	+	27760321	MV411	viability	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.8157684769262156	[759,641]	[951,599]	6	hSpCas9	negative selection	4565762
42718549	42718571	17	-	27760321	MV411	viability	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	-0.15846783234002243	[654,494]	[102,688]	-1	hSpCas9	negative selection	4565763
42720421	42720443	17	+	27760321	MV411	viability	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.8753058983147577	[390,303]	[555,209]	6	hSpCas9	negative selection	4565764
42713327	42713349	17	-	27760321	HL60	viability	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.19373944367176987	[1081,979]	[844,619]	-2	hSpCas9	negative selection	4649223
42718467	42718489	17	+	27760321	HL60	viability	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.5664762741146852	[291,234]	[47,97]	-8	hSpCas9	negative selection	4649224
42718525	42718547	17	+	27760321	HL60	viability	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	-0.3778572907995366	[759,641]	[441,435]	-4	hSpCas9	negative selection	4649225
42718549	42718571	17	-	27760321	HL60	viability	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.06453756708340164	[654,494]	[443,532]	0	hSpCas9	negative selection	4649226
42720421	42720443	17	+	27760321	HL60	viability	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.39017338103827814	[390,303]	[316,424]	5	hSpCas9	negative selection	4649227
42713327	42713349	17	-	27760321	HT1080	viability	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	0.4752924129566165	[979,764]	[455,512]	2	hSpCas9	negative selection	4732686
42718467	42718489	17	+	27760321	HT1080	viability	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.18398057749424668	[234,183]	[51,96]	-1	hSpCas9	negative selection	4732687
42718525	42718547	17	+	27760321	HT1080	viability	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	1.1853852938792107	[641,500]	[533,499]	6	hSpCas9	negative selection	4732688
42718549	42718571	17	-	27760321	HT1080	viability	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.962967997245039	[494,385]	[300,386]	5	hSpCas9	negative selection	4732689
42720421	42720443	17	+	27760321	HT1080	viability	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.14712933294316655	[303,236]	[104,134]	0	hSpCas9	negative selection	4732690
42713327	42713349	17	-	27760321	HT29	viability after 7 days	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.16806767224178532	[979,764]	[1137,1011,867]	-2	hSpCas9	negative selection	4816149
42718467	42718489	17	+	27760321	HT29	viability after 7 days	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.727074992899327	[234,183]	[142,235,107]	-7	hSpCas9	negative selection	4816150
42718525	42718547	17	+	27760321	HT29	viability after 7 days	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	-0.15414567210087082	[641,500]	[693,445,838]	-2	hSpCas9	negative selection	4816151
42718549	42718571	17	-	27760321	HT29	viability after 7 days	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.2125403907779888	[494,385]	[612,706,641]	3	hSpCas9	negative selection	4816152
42720421	42720443	17	+	27760321	HT29	viability after 7 days	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.49589236525071606	[303,236]	[613,410,463]	7	hSpCas9	negative selection	4816153
42713327	42713349	17	-	27760321	HT29	viability after 25 days	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.15541120983053025	[979,764]	[839,926,923]	-2	hSpCas9	negative selection	4899612
42718467	42718489	17	+	27760321	HT29	viability after 25 days	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.712625950847923	[234,183]	[75,111,25]	-7	hSpCas9	negative selection	4899613
42718525	42718547	17	+	27760321	HT29	viability after 25 days	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.5551277582197331	[641,500]	[972,836,1078]	6	hSpCas9	negative selection	4899614
42718549	42718571	17	-	27760321	HT29	viability after 25 days	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	-0.17501339469423	[494,385]	[224,497,648]	-2	hSpCas9	negative selection	4899615
42720421	42720443	17	+	27760321	HT29	viability after 25 days	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.33275872072877366	[303,236]	[459,208,505]	3	hSpCas9	negative selection	4899616
42713327	42713349	17	-	27760321	HT29	viability after 22 days	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.3375188292791521	[979,764]	[1110,611,661]	-3	hSpCas9	negative selection	4983075
42718467	42718489	17	+	27760321	HT29	viability after 22 days	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.346946466624211	[234,183]	[128,36,118]	-7	hSpCas9	negative selection	4983076
42718525	42718547	17	+	27760321	HT29	viability after 22 days	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.07531446532392494	[641,500]	[613,721,754]	0	hSpCas9	negative selection	4983077
42718549	42718571	17	-	27760321	HT29	viability after 22 days	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	-0.05043839672728356	[494,385]	[578,482,409]	0	hSpCas9	negative selection	4983078
42720421	42720443	17	+	27760321	HT29	viability after 22 days	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.08064911038542943	[303,236]	[395,286,306]	0	hSpCas9	negative selection	4983079
42713327	42713349	17	-	27760321	HT29	viability after 19 days	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.3368226068282365	[979,764]	[795,559,1005]	-3	hSpCas9	negative selection	5066538
42718467	42718489	17	+	27760321	HT29	viability after 19 days	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.4263482547779962	[234,183]	[72,29,159]	-7	hSpCas9	negative selection	5066539
42718525	42718547	17	+	27760321	HT29	viability after 19 days	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.4039254283466607	[641,500]	[721,1210,653]	4	hSpCas9	negative selection	5066540
42718549	42718571	17	-	27760321	HT29	viability after 19 days	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	-0.0033881520530930076	[494,385]	[565,497,451]	0	hSpCas9	negative selection	5066541
42720421	42720443	17	+	27760321	HT29	viability after 19 days	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.35643358243378137	[303,236]	[401,350,433]	3	hSpCas9	negative selection	5066542
42713327	42713349	17	-	27760321	HT29	viability after 16 days	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.3816255525045792	[979,764]	[988,724,556]	-4	hSpCas9	negative selection	5150001
42718467	42718489	17	+	27760321	HT29	viability after 16 days	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.3896630827076824	[234,183]	[65,134,63]	-7	hSpCas9	negative selection	5150002
42718525	42718547	17	+	27760321	HT29	viability after 16 days	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.27578454409167796	[641,500]	[612,463,1237]	3	hSpCas9	negative selection	5150003
42718549	42718571	17	-	27760321	HT29	viability after 16 days	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	0.14847877306599389	[494,385]	[494,421,719]	1	hSpCas9	negative selection	5150004
42720421	42720443	17	+	27760321	HT29	viability after 16 days	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.4075654286232725	[303,236]	[704,164,368]	4	hSpCas9	negative selection	5150005
42713327	42713349	17	-	27760321	HT29	viability after 13 days	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.3705674898020014	[979,764]	[670,811,860]	-4	hSpCas9	negative selection	5233464
42718467	42718489	17	+	27760321	HT29	viability after 13 days	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.5308959797547563	[234,183]	[288,107,110]	-5	hSpCas9	negative selection	5233465
42718525	42718547	17	+	27760321	HT29	viability after 13 days	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.26284021902475363	[641,500]	[515,1075,794]	3	hSpCas9	negative selection	5233466
42718549	42718571	17	-	27760321	HT29	viability after 13 days	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	-0.09284630079785974	[494,385]	[422,526,486]	-1	hSpCas9	negative selection	5233467
42720421	42720443	17	+	27760321	HT29	viability after 13 days	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	-0.24991711225657548	[303,236]	[164,331,292]	-3	hSpCas9	negative selection	5233468
42713327	42713349	17	-	27760321	HT29	viability after 10 days	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	-0.2795101051298725	[979,764]	[939,830,918]	-4	hSpCas9	negative selection	5316927
42718467	42718489	17	+	27760321	HT29	viability after 10 days	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.2245657545492123	[234,183]	[73,151,110]	-8	hSpCas9	negative selection	5316928
42718525	42718547	17	+	27760321	HT29	viability after 10 days	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	0.10639367989647519	[641,500]	[464,876,960]	1	hSpCas9	negative selection	5316929
42718549	42718571	17	-	27760321	HT29	viability after 10 days	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	-0.007076784142775849	[494,385]	[613,462,561]	0	hSpCas9	negative selection	5316930
42720421	42720443	17	+	27760321	HT29	viability after 10 days	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.2545167793400423	[303,236]	[485,394,328]	3	hSpCas9	negative selection	5316931
42713327	42713349	17	-	27760321	MOLM13	viability	CAAGTGCTCTGGTCGTCGCCGG	EZH1	ENSG00000108799	0.9557490808570357	[1081,979]	[819,1388]	6	hSpCas9	negative selection	5400390
42718467	42718489	17	+	27760321	MOLM13	viability	GTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.010011354389163007	[291,234]	[108,178]	0	hSpCas9	negative selection	5400391
42718525	42718547	17	+	27760321	MOLM13	viability	CGCTGCACAGACTTGGCATTGG	EZH1	ENSG00000108799	-0.8239187179762836	[759,641]	[321,137]	-5	hSpCas9	negative selection	5400392
42718549	42718571	17	-	27760321	MOLM13	viability	AGTGCACACCCAACATCGATGG	EZH1	ENSG00000108799	1.0390750857325206	[654,494]	[348,926]	7	hSpCas9	negative selection	5400393
42720421	42720443	17	+	27760321	MOLM13	viability	ACTAATCAGAACGGATCCAGGG	EZH1	ENSG00000108799	0.9941394651865676	[390,303]	[403,373]	7	hSpCas9	negative selection	5400394
42744844	42744867	17	-	27661255	K562	viability	GGCGCCCCTCCTCATTCCGAGGG	EZH1	ENSG00000108799	0.16373066890334775	[713,818]	[708,662]	6	dCas9-KRAB	negative selection	5478214
42744988	42745011	17	-	27661255	K562	viability	GTGAGTGAGTAAACAAGCCTGGG	EZH1	ENSG00000108799	0.004495720482163956	[1157,1186]	[991,893]	0	dCas9-KRAB	negative selection	5478215
42745010	42745033	17	-	27661255	K562	viability	GACCCGCGGCTCGGGATGGAGGG	EZH1	ENSG00000108799	-0.08393827958339195	[412,397]	[375,245]	-3	dCas9-KRAB	negative selection	5478216
42745014	42745037	17	-	27661255	K562	viability	GCGGGACCCGCGGCTCGGGATGG	EZH1	ENSG00000108799	0.1913895274491374	[391,612]	[505,410]	6	dCas9-KRAB	negative selection	5478217
42745033	42745056	17	-	27661255	K562	viability	GCGCGCATGCGTCCTAGCAGCGG	EZH1	ENSG00000108799	0.46740552153250914	[275,436]	[450,338]	9	dCas9-KRAB	negative selection	5478218
42727660	42727683	17	+	27260156	BXPC3	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.1940934695599711	[964]	[874,922,814,908]	-4	hSpCas9	negative selection	5541981
42722814	42722837	17	-	27260156	BXPC3	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.18026373099444243	[568]	[464,525,621,486]	-4	hSpCas9	negative selection	5541982
42720369	42720392	17	+	27260156	BXPC3	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.3394023059632665	[1325]	[1571,1510,1861,2143]	7	hSpCas9	negative selection	5541983
42720272	42720295	17	-	27260156	BXPC3	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.43651004159715917	[474]	[361,249,406,466]	-7	hSpCas9	negative selection	5606246
42722786	42722809	17	+	27260156	BXPC3	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.15229868527819423	[639]	[797,687,650,839]	3	hSpCas9	negative selection	5606247
42727751	42727774	17	-	27260156	BXPC3	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.05533147753585277	[573]	[626,757,443,652]	1	hSpCas9	negative selection	5606248
42727660	42727683	17	+	27260156	A673	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.08620294739203649	[964]	[1369,1158,1121,1288]	2	hSpCas9	negative selection	5663232
42722814	42722837	17	-	27260156	A673	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.021521354129430903	[568]	[686,607,650,752]	0	hSpCas9	negative selection	5663233
42720369	42720392	17	+	27260156	A673	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.3318741592836074	[1325]	[1937,1838,1985,2259]	7	hSpCas9	negative selection	5663234
42720272	42720295	17	-	27260156	A673	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.18261186299966797	[474]	[579,457,470,510]	-4	hSpCas9	negative selection	5727497
42722786	42722809	17	+	27260156	A673	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.3143330136485726	[639]	[932,1008,941,930]	7	hSpCas9	negative selection	5727498
42727751	42727774	17	-	27260156	A673	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.16919067523870146	[573]	[769,876,615,836]	4	hSpCas9	negative selection	5727499
42727660	42727683	17	+	27260156	A375	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.2277808182840254	[964]	[905,1295,873,831]	-3	hSpCas9	negative selection	5784483
42722814	42722837	17	-	27260156	A375	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.1778375619525422	[568]	[832,883,737,587]	2	hSpCas9	negative selection	5784484
42720369	42720392	17	+	27260156	A375	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.5841036349053668	[1325]	[2055,2749,2590,1979]	8	hSpCas9	negative selection	5784485
42720272	42720295	17	-	27260156	A375	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.14610355228669147	[474]	[489,416,456,613]	-2	hSpCas9	negative selection	5848748
42722786	42722809	17	+	27260156	A375	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.12031292222095391	[639]	[585,908,833,916]	1	hSpCas9	negative selection	5848749
42727751	42727774	17	-	27260156	A375	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.33604823802535766	[573]	[747,1061,901,714]	5	hSpCas9	negative selection	5848750
42727660	42727683	17	+	27260156	COLO741	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.006046850090855038	[964]	[1544,1073,1097]	0	hSpCas9	negative selection	5905734
42722814	42722837	17	-	27260156	COLO741	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.10126140640559275	[568]	[870,614,569]	-2	hSpCas9	negative selection	5905735
42720369	42720392	17	+	27260156	COLO741	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.551938041149934	[1325]	[3128,2118,2267]	9	hSpCas9	negative selection	5905736
42720272	42720295	17	-	27260156	COLO741	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.04341111198304891	[474]	[542,578,635]	-1	hSpCas9	negative selection	5969999
42722786	42722809	17	+	27260156	COLO741	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.2612172960191107	[639]	[1033,1103,816]	5	hSpCas9	negative selection	5970000
42727751	42727774	17	-	27260156	COLO741	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.27344510497233543	[573]	[1182,766,742]	6	hSpCas9	negative selection	5970001
42727660	42727683	17	+	27260156	CAL120	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.21406853992804187	[964]	[1280,754,1104]	-3	hSpCas9	negative selection	6026985
42722814	42722837	17	-	27260156	CAL120	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.14657806601999834	[568]	[588,853,876]	2	hSpCas9	negative selection	6026986
42720369	42720392	17	+	27260156	CAL120	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.4256555593864284	[1325]	[2426,1937,2312]	6	hSpCas9	negative selection	6026987
42720272	42720295	17	-	27260156	CAL120	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.36328827827922183	[474]	[386,497,481]	-5	hSpCas9	negative selection	6091250
42722786	42722809	17	+	27260156	CAL120	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.26942097710134605	[639]	[1201,1043,674]	4	hSpCas9	negative selection	6091251
42727751	42727774	17	-	27260156	CAL120	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.056329719116707755	[573]	[866,773,607]	0	hSpCas9	negative selection	6091252
42727660	42727683	17	+	27260156	CADOES1	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.2536720165186285	[964]	[688,721,929,666]	-4	hSpCas9	negative selection	6148236
42722814	42722837	17	-	27260156	CADOES1	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.25291619598078996	[568]	[693,800,464,559]	4	hSpCas9	negative selection	6148237
42720369	42720392	17	+	27260156	CADOES1	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.44888891818002974	[1325]	[1592,1785,1568,1789]	7	hSpCas9	negative selection	6148238
42720272	42720295	17	-	27260156	CADOES1	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.07051098447406302	[474]	[447,448,436,345]	-1	hSpCas9	negative selection	6212501
42722786	42722809	17	+	27260156	CADOES1	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.0911338807973534	[639]	[560,726,603,644]	1	hSpCas9	negative selection	6212502
42727751	42727774	17	-	27260156	CADOES1	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.0708201072250278	[573]	[429,550,551,715]	1	hSpCas9	negative selection	6212503
42727660	42727683	17	+	27260156	EWS502	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.13160503591290018	[964]	[776,797,962,1236]	-2	hSpCas9	negative selection	6269487
42722814	42722837	17	-	27260156	EWS502	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.1789512283557636	[568]	[594,510,779,872]	3	hSpCas9	negative selection	6269488
42720369	42720392	17	+	27260156	EWS502	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.35863637470378307	[1325]	[1617,2030,1670,1893]	6	hSpCas9	negative selection	6269489
42720272	42720295	17	-	27260156	EWS502	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.27968568348089373	[474]	[371,435,482,366]	-5	hSpCas9	negative selection	6333752
42722786	42722809	17	+	27260156	EWS502	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.06212966750220866	[639]	[580,517,690,831]	-1	hSpCas9	negative selection	6333753
42727751	42727774	17	-	27260156	EWS502	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.12194109652414326	[573]	[459,604,795,822]	2	hSpCas9	negative selection	6333754
42727660	42727683	17	+	27260156	EW8	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.14035627629916703	[964]	[826,1030,721,885]	2	hSpCas9	negative selection	6390738
42722814	42722837	17	-	27260156	EW8	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.009712361630012267	[568]	[522,470,369,513]	0	hSpCas9	negative selection	6390739
42720369	42720392	17	+	27260156	EW8	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.42999694842508385	[1325]	[1551,1556,1107,1638]	7	hSpCas9	negative selection	6390740
42720272	42720295	17	-	27260156	EW8	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	0.20530725659867377	[474]	[603,396,417,376]	4	hSpCas9	negative selection	6455003
42722786	42722809	17	+	27260156	EW8	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.12022630675433088	[639]	[605,622,410,643]	2	hSpCas9	negative selection	6455004
42727751	42727774	17	-	27260156	EW8	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.07190956122632491	[573]	[503,522,376,570]	1	hSpCas9	negative selection	6455005
42727660	42727683	17	+	27260156	CORL105	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.16452073325328165	[964]	[1085,742,1216,1025]	-3	hSpCas9	negative selection	6511989
42722814	42722837	17	-	27260156	CORL105	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.0020668598251541437	[568]	[540,766,995,402]	0	hSpCas9	negative selection	6511990
42720369	42720392	17	+	27260156	CORL105	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.35950945176752835	[1325]	[2205,1782,2308,1729]	6	hSpCas9	negative selection	6511991
42720272	42720295	17	-	27260156	CORL105	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.22685801239919476	[474]	[519,351,611,441]	-4	hSpCas9	negative selection	6576254
42722786	42722809	17	+	27260156	CORL105	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.20323893695417872	[639]	[642,637,701,627]	-4	hSpCas9	negative selection	6576255
42727751	42727774	17	-	27260156	CORL105	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.10121954662648419	[573]	[625,808,720,721]	2	hSpCas9	negative selection	6576256
42727660	42727683	17	+	27260156	HS294T	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.1891795627456916	[964]	[362,266,351,323]	-3	hSpCas9	negative selection	6633240
42722814	42722837	17	-	27260156	HS294T	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.3147446260030582	[568]	[232,316,232,320]	4	hSpCas9	negative selection	6633241
42720369	42720392	17	+	27260156	HS294T	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.879267457986447	[1325]	[918,811,666,1464]	9	hSpCas9	negative selection	6633242
42720272	42720295	17	-	27260156	HS294T	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	0.0726208331841987	[474]	[237,178,162,186]	1	hSpCas9	negative selection	6697505
42722786	42722809	17	+	27260156	HS294T	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.3144324668681151	[639]	[198,212,177,205]	-4	hSpCas9	negative selection	6697506
42727751	42727774	17	-	27260156	HS294T	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.3690737101913679	[573]	[202,396,212,346]	5	hSpCas9	negative selection	6697507
42727660	42727683	17	+	27260156	HCC44	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.24464808314137376	[964]	[1154,1673,1101,1135]	4	hSpCas9	negative selection	6754491
42722814	42722837	17	-	27260156	HCC44	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.09125245318069042	[568]	[729,498,654,563]	-1	hSpCas9	negative selection	6754492
42720369	42720392	17	+	27260156	HCC44	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.46849043830639836	[1325]	[2044,1853,2995,1591]	7	hSpCas9	negative selection	6754493
42720272	42720295	17	-	27260156	HCC44	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.4211420387790498	[474]	[545,335,390,350]	-6	hSpCas9	negative selection	6818756
42722786	42722809	17	+	27260156	HCC44	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.18665019916181136	[639]	[1073,676,876,716]	3	hSpCas9	negative selection	6818757
42727751	42727774	17	-	27260156	HCC44	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.3482681767277518	[573]	[784,670,943,933]	5	hSpCas9	negative selection	6818758
42727660	42727683	17	+	27260156	G402	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.11327516486481592	[964]	[1533,1215,883,801]	-1	hSpCas9	negative selection	6875742
42722814	42722837	17	-	27260156	G402	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.6702733808364852	[568]	[1000,975,1718,715]	8	hSpCas9	negative selection	6875743
42720369	42720392	17	+	27260156	G402	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.5000835630484863	[1325]	[2851,2075,2602,1710]	6	hSpCas9	negative selection	6875744
42720272	42720295	17	-	27260156	G402	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.6988871875644599	[474]	[365,321,272,459]	-7	hSpCas9	negative selection	6940007
42722786	42722809	17	+	27260156	G402	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.0051396203961371345	[639]	[1018,667,474,986]	0	hSpCas9	negative selection	6940008
42727751	42727774	17	-	27260156	G402	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.45646288813029146	[573]	[1202,758,1306,611]	5	hSpCas9	negative selection	6940009
42727660	42727683	17	+	27260156	L33	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.02014682348875274	[964]	[778,393,621,1186]	0	hSpCas9	negative selection	6996993
42722814	42722837	17	-	27260156	L33	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.007829776044934567	[568]	[508,214,335,719]	0	hSpCas9	negative selection	6996994
42720369	42720392	17	+	27260156	L33	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.3807896362211949	[1325]	[1838,662,994,1860]	7	hSpCas9	negative selection	6996995
42720272	42720295	17	-	27260156	L33	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.15284168868309383	[474]	[387,156,319,429]	-3	hSpCas9	negative selection	7061258
42722786	42722809	17	+	27260156	L33	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.18867260588403234	[639]	[524,247,384,504]	-4	hSpCas9	negative selection	7061259
42727751	42727774	17	-	27260156	L33	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.1596344210756145	[573]	[499,248,343,401]	-4	hSpCas9	negative selection	7061260
42727660	42727683	17	+	27260156	K562	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.167056949350594	[964]	[502,980,1065,516]	-2	hSpCas9	negative selection	7118244
42722814	42722837	17	-	27260156	K562	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.3781411341041171	[568]	[1070,554,416,612]	5	hSpCas9	negative selection	7118245
42720369	42720392	17	+	27260156	K562	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.8318214491488352	[1325]	[1730,2230,2266,2114]	9	hSpCas9	negative selection	7118246
42720272	42720295	17	-	27260156	K562	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.10864497372199078	[474]	[510,518,405,168]	-1	hSpCas9	negative selection	7182509
42722786	42722809	17	+	27260156	K562	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.08456572557919739	[639]	[452,374,713,814]	1	hSpCas9	negative selection	7182510
42727751	42727774	17	-	27260156	K562	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.027763718994388342	[573]	[589,624,443,436]	0	hSpCas9	negative selection	7182511
42727660	42727683	17	+	27260156	HT29	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.014653003786954333	[964]	[1418,1198,1129,1022]	0	hSpCas9	negative selection	7239495
42722814	42722837	17	-	27260156	HT29	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.01917507612347985	[568]	[643,787,751,626]	0	hSpCas9	negative selection	7239496
42720369	42720392	17	+	27260156	HT29	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.3877096967134346	[1325]	[2490,2050,2192,1753]	7	hSpCas9	negative selection	7239497
42720272	42720295	17	-	27260156	HT29	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.06384885610405966	[474]	[433,591,648,527]	-1	hSpCas9	negative selection	7303760
42722786	42722809	17	+	27260156	HT29	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.049403682945762195	[639]	[911,693,943,678]	0	hSpCas9	negative selection	7303761
42727751	42727774	17	-	27260156	HT29	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.03653559623698671	[573]	[830,646,779,614]	0	hSpCas9	negative selection	7303762
42727660	42727683	17	+	27260156	MHHES1	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.18277546417077417	[964]	[1174,1414,1253,1103]	3	hSpCas9	negative selection	7360746
42722814	42722837	17	-	27260156	MHHES1	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.12002941150061663	[568]	[743,611,556,478]	-2	hSpCas9	negative selection	7360747
42720369	42720392	17	+	27260156	MHHES1	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.40108807366269295	[1325]	[2005,1915,2262,1717]	7	hSpCas9	negative selection	7360748
42720272	42720295	17	-	27260156	MHHES1	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.32015419977485843	[474]	[477,756,284,261]	-6	hSpCas9	negative selection	7425011
42722786	42722809	17	+	27260156	MHHES1	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.13936692683573293	[639]	[1088,916,616,621]	2	hSpCas9	negative selection	7425012
42727751	42727774	17	-	27260156	MHHES1	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.09978854630320899	[573]	[749,747,774,532]	1	hSpCas9	negative selection	7425013
42727660	42727683	17	+	27260156	MEWO	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.05675648212365825	[964]	[1030,735,868]	-1	hSpCas9	negative selection	7481997
42722814	42722837	17	-	27260156	MEWO	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.029472536375832276	[568]	[526,448,589]	0	hSpCas9	negative selection	7481998
42720369	42720392	17	+	27260156	MEWO	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.358343494902829	[1325]	[2137,1333,1405]	7	hSpCas9	negative selection	7481999
42720272	42720295	17	-	27260156	MEWO	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.5425486797729528	[474]	[286,248,375]	-8	hSpCas9	negative selection	7546262
42722786	42722809	17	+	27260156	MEWO	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.12223325874234642	[639]	[695,446,535]	-3	hSpCas9	negative selection	7546263
42727751	42727774	17	-	27260156	MEWO	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.058157910563959636	[573]	[650,405,516]	-1	hSpCas9	negative selection	7546264
42727660	42727683	17	+	27260156	LNCAPCLONEFGC	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.23409360640904453	[964]	[706,877,849,544]	-4	hSpCas9	negative selection	7603248
42722814	42722837	17	-	27260156	LNCAPCLONEFGC	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.03292595805660803	[568]	[618,574,479,422]	0	hSpCas9	negative selection	7603249
42720369	42720392	17	+	27260156	LNCAPCLONEFGC	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.4524070527673394	[1325]	[1278,1371,2052,1954]	7	hSpCas9	negative selection	7603250
42720272	42720295	17	-	27260156	LNCAPCLONEFGC	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.3593421026849576	[474]	[284,286,546,257]	-5	hSpCas9	negative selection	7667513
42722786	42722809	17	+	27260156	LNCAPCLONEFGC	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.207442846207892	[639]	[647,656,740,642]	3	hSpCas9	negative selection	7667514
42727751	42727774	17	-	27260156	LNCAPCLONEFGC	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.4774279308801649	[573]	[925,666,588,692]	7	hSpCas9	negative selection	7667515
42727660	42727683	17	+	27260156	PANC0327	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.0711773416576138	[964]	[943,1097,791,745]	1	hSpCas9	negative selection	7724499
42722814	42722837	17	-	27260156	PANC0327	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.3451797867912918	[568]	[683,339,922,663]	5	hSpCas9	negative selection	7724500
42720369	42720392	17	+	27260156	PANC0327	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.2721734342243607	[1325]	[2199,901,1239,1477]	4	hSpCas9	negative selection	7724501
42720272	42720295	17	-	27260156	PANC0327	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	0.07121357346094855	[474]	[380,437,617,331]	1	hSpCas9	negative selection	7788764
42722786	42722809	17	+	27260156	PANC0327	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.012546554290225997	[639]	[364,558,820,493]	0	hSpCas9	negative selection	7788765
42727751	42727774	17	-	27260156	PANC0327	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.22553128726678173	[573]	[919,340,602,579]	3	hSpCas9	negative selection	7788766
42727660	42727683	17	+	27260156	NCIH2009	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.33886933068791514	[964]	[1380,1092,783]	-4	hSpCas9	negative selection	7845750
42722814	42722837	17	-	27260156	NCIH2009	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.05275497844090721	[568]	[981,685,837]	0	hSpCas9	negative selection	7845751
42720369	42720392	17	+	27260156	NCIH2009	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.5148133823783634	[1325]	[2902,2440,2646]	7	hSpCas9	negative selection	7845752
42720272	42720295	17	-	27260156	NCIH2009	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.24904467120682366	[474]	[587,733,354]	-3	hSpCas9	negative selection	7910015
42722786	42722809	17	+	27260156	NCIH2009	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.34687304195226654	[639]	[1089,566,529]	-5	hSpCas9	negative selection	7910016
42727751	42727774	17	-	27260156	NCIH2009	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.25163338053006823	[573]	[947,1196,711]	3	hSpCas9	negative selection	7910017
42727660	42727683	17	+	27260156	NCIH1373	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.07564682942488554	[964]	[1541,1223,823,266]	0	hSpCas9	negative selection	7967001
42722814	42722837	17	-	27260156	NCIH1373	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.7050232152816638	[568]	[1906,713,825,228]	7	hSpCas9	negative selection	7967002
42720369	42720392	17	+	27260156	NCIH1373	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.6706142965090729	[1325]	[2317,2298,2316,663]	6	hSpCas9	negative selection	7967003
42720272	42720295	17	-	27260156	NCIH1373	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.6698661884953598	[474]	[371,310,344,82]	-6	hSpCas9	negative selection	8031266
42722786	42722809	17	+	27260156	NCIH1373	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.28593725107880597	[639]	[1083,571,751,307]	3	hSpCas9	negative selection	8031267
42727751	42727774	17	-	27260156	NCIH1373	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.28135688509509404	[573]	[699,839,909,168]	2	hSpCas9	negative selection	8031268
42727660	42727683	17	+	27260156	PATU8902	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-1.0470413010949855	[964]	[355,704,589,1007]	-7	hSpCas9	negative selection	8088252
42722814	42722837	17	-	27260156	PATU8902	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.36189288457306124	[568]	[1172,752,746,1519]	4	hSpCas9	negative selection	8088253
42720369	42720392	17	+	27260156	PATU8902	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.43839396334460234	[1325]	[2769,2194,2530,2478]	4	hSpCas9	negative selection	8088254
42720272	42720295	17	-	27260156	PATU8902	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-1.48037446796404	[474]	[86,65,490,237]	-8	hSpCas9	negative selection	8152517
42722786	42722809	17	+	27260156	PATU8902	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.4210996287221361	[639]	[724,760,600,575]	-4	hSpCas9	negative selection	8152518
42727751	42727774	17	-	27260156	PATU8902	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.11912496978889475	[573]	[789,1162,419,1257]	1	hSpCas9	negative selection	8152519
42727660	42727683	17	+	27260156	PANC1	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.1228745162097622	[964]	[805,1043,682,584]	-2	hSpCas9	negative selection	8209503
42722814	42722837	17	-	27260156	PANC1	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.1858096758470401	[568]	[461,775,527,503]	3	hSpCas9	negative selection	8209504
42720369	42720392	17	+	27260156	PANC1	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.3994112386654607	[1325]	[1493,2008,1546,1104]	6	hSpCas9	negative selection	8209505
42720272	42720295	17	-	27260156	PANC1	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.41984835573201346	[474]	[407,266,362,186]	-6	hSpCas9	negative selection	8273768
42722786	42722809	17	+	27260156	PANC1	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.11606646591375303	[639]	[534,620,708,526]	1	hSpCas9	negative selection	8273769
42727751	42727774	17	-	27260156	PANC1	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.3556042079877977	[573]	[576,705,739,524]	6	hSpCas9	negative selection	8273770
42727660	42727683	17	+	27260156	PANC0813	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.04160285521548934	[964]	[1325,993,1160,951]	0	hSpCas9	negative selection	8330754
42722814	42722837	17	-	27260156	PANC0813	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.29067377928385746	[568]	[713,413,470,597]	-4	hSpCas9	negative selection	8330755
42720369	42720392	17	+	27260156	PANC0813	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.5269766333437165	[1325]	[2673,2114,2217,2018]	8	hSpCas9	negative selection	8330756
42720272	42720295	17	-	27260156	PANC0813	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.7339132366016927	[474]	[343,339,423,239]	-8	hSpCas9	negative selection	8395019
42722786	42722809	17	+	27260156	PANC0813	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.1657278604223167	[639]	[778,721,803,1048]	2	hSpCas9	negative selection	8395020
42727751	42727774	17	-	27260156	PANC0813	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.19053997530497463	[573]	[832,570,461,521]	-3	hSpCas9	negative selection	8395021
42727660	42727683	17	+	27260156	RDES	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.22781245107273773	[964]	[789,880,1076,1078]	-4	hSpCas9	negative selection	8452005
42722814	42722837	17	-	27260156	RDES	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.11266843079061745	[568]	[502,674,614,1124]	1	hSpCas9	negative selection	8452006
42720369	42720392	17	+	27260156	RDES	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.5384789957514351	[1325]	[1750,2116,2282,2851]	8	hSpCas9	negative selection	8452007
42720272	42720295	17	-	27260156	RDES	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.5536046202005872	[474]	[278,351,390,497]	-7	hSpCas9	negative selection	8516270
42722786	42722809	17	+	27260156	RDES	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.05996848780014297	[639]	[608,676,681,883]	-1	hSpCas9	negative selection	8516271
42727751	42727774	17	-	27260156	RDES	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.11373987022678964	[573]	[495,592,719,648]	-2	hSpCas9	negative selection	8516272
42727660	42727683	17	+	27260156	PC3	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.05640850980262946	[964]	[526,917,1571,1350]	1	hSpCas9	negative selection	8573256
42722814	42722837	17	-	27260156	PC3	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.007173106284219077	[568]	[392,473,990,610]	0	hSpCas9	negative selection	8573257
42720369	42720392	17	+	27260156	PC3	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.39983598652893937	[1325]	[1163,2094,2308,1673]	8	hSpCas9	negative selection	8573258
42720272	42720295	17	-	27260156	PC3	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.09479985277360824	[474]	[252,464,611,555]	-2	hSpCas9	negative selection	8637521
42722786	42722809	17	+	27260156	PC3	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.21832189671875557	[639]	[427,744,1194,851]	5	hSpCas9	negative selection	8637522
42727751	42727774	17	-	27260156	PC3	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.06250768237513127	[573]	[339,395,969,704]	-1	hSpCas9	negative selection	8637523
42727660	42727683	17	+	27260156	PATU8988T	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.045986493328957545	[964]	[781,1126,851,1118]	0	hSpCas9	negative selection	8694507
42722814	42722837	17	-	27260156	PATU8988T	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.09746139210262744	[568]	[565,486,708,578]	1	hSpCas9	negative selection	8694508
42720369	42720392	17	+	27260156	PATU8988T	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.21744412254079015	[1325]	[1347,1372,1414,1840]	4	hSpCas9	negative selection	8694509
42720272	42720295	17	-	27260156	PATU8988T	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.4163729509195614	[474]	[417,388,312,252]	-6	hSpCas9	negative selection	8758772
42722786	42722809	17	+	27260156	PATU8988T	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.1738640876721093	[639]	[537,724,354,597]	-3	hSpCas9	negative selection	8758773
42727751	42727774	17	-	27260156	PATU8988T	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.14332538904417863	[573]	[838,534,410,664]	2	hSpCas9	negative selection	8758774
42727660	42727683	17	+	27260156	T47D	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.15712493919014925	[964]	[1067,801,969,1217]	-4	hSpCas9	negative selection	8815758
42722814	42722837	17	-	27260156	T47D	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.14424039844989212	[568]	[615,731,822,757]	3	hSpCas9	negative selection	8815759
42720369	42720392	17	+	27260156	T47D	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.27897671796101986	[1325]	[1790,1761,1951,2003]	6	hSpCas9	negative selection	8815760
42720272	42720295	17	-	27260156	T47D	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.26528894766427596	[474]	[468,437,460,475]	-5	hSpCas9	negative selection	8880023
42722786	42722809	17	+	27260156	T47D	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.009619041015260288	[639]	[699,686,756,866]	0	hSpCas9	negative selection	8880024
42727751	42727774	17	-	27260156	T47D	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.10664977962104288	[573]	[761,654,690,779]	2	hSpCas9	negative selection	8880025
42727660	42727683	17	+	27260156	SU8686	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.04859605337048589	[964]	[903,878,1014,1213]	0	hSpCas9	negative selection	8937009
42722814	42722837	17	-	27260156	SU8686	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.2382288510838962	[568]	[504,364,524,536]	-4	hSpCas9	negative selection	8937010
42720369	42720392	17	+	27260156	SU8686	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.44578610111456474	[1325]	[1612,1473,2125,2048]	7	hSpCas9	negative selection	8937011
42720272	42720295	17	-	27260156	SU8686	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.5067272204083811	[474]	[365,297,275,391]	-7	hSpCas9	negative selection	9001274
42722786	42722809	17	+	27260156	SU8686	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.015376850162053535	[639]	[431,690,655,829]	0	hSpCas9	negative selection	9001275
42727751	42727774	17	-	27260156	SU8686	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.19130897344727063	[573]	[444,474,541,545]	-3	hSpCas9	negative selection	9001276
42727660	42727683	17	+	27260156	SKES1	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.13274368940507908	[964]	[939,1043,744,811]	-3	hSpCas9	negative selection	9058260
42722814	42722837	17	-	27260156	SKES1	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.30352070928075003	[568]	[817,902,614,521]	6	hSpCas9	negative selection	9058261
42720369	42720392	17	+	27260156	SKES1	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.5047445861397759	[1325]	[2242,2122,1686,1555]	8	hSpCas9	negative selection	9058262
42720272	42720295	17	-	27260156	SKES1	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.22088711580995166	[474]	[461,297,584,283]	-5	hSpCas9	negative selection	9122525
42722786	42722809	17	+	27260156	SKES1	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.13067609450598816	[639]	[632,691,788,666]	3	hSpCas9	negative selection	9122526
42727751	42727774	17	-	27260156	SKES1	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.39872692915646135	[573]	[924,924,781,458]	7	hSpCas9	negative selection	9122527
42727660	42727683	17	+	27260156	TOV112D	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.23827320445124978	[964]	[1030,1065,706,557]	-5	hSpCas9	negative selection	9179511
42722814	42722837	17	-	27260156	TOV112D	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.09271971868580109	[568]	[735,765,420,557]	1	hSpCas9	negative selection	9179512
42720369	42720392	17	+	27260156	TOV112D	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.36569145776387035	[1325]	[1762,2538,1542,1218]	7	hSpCas9	negative selection	9179513
42720272	42720295	17	-	27260156	TOV112D	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.6220057121369418	[474]	[276,415,200,363]	-8	hSpCas9	negative selection	9243776
42722786	42722809	17	+	27260156	TOV112D	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.06407563413079631	[639]	[603,1056,475,632]	1	hSpCas9	negative selection	9243777
42727751	42727774	17	-	27260156	TOV112D	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.22680573633150558	[573]	[757,927,512,563]	4	hSpCas9	negative selection	9243778
42727660	42727683	17	+	27260156	TC71	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.025233510232215206	[964]	[955,983,1079,1046]	0	hSpCas9	negative selection	9300762
42722814	42722837	17	-	27260156	TC71	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	-0.06671477844897333	[568]	[615,531,519,667]	-2	hSpCas9	negative selection	9300763
42720369	42720392	17	+	27260156	TC71	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.18979840880196241	[1325]	[1650,1313,1703,1824]	5	hSpCas9	negative selection	9300764
42720272	42720295	17	-	27260156	TC71	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.13012966823275637	[474]	[462,422,424,556]	-3	hSpCas9	negative selection	9365027
42722786	42722809	17	+	27260156	TC71	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.15537537984679517	[639]	[712,724,875,737]	4	hSpCas9	negative selection	9365028
42727751	42727774	17	-	27260156	TC71	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	0.23633226021629772	[573]	[651,680,799,767]	6	hSpCas9	negative selection	9365029
42727660	42727683	17	+	27260156	TC32	viability	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.06589233019345875	[964]	[890,546,1030,1105]	-1	hSpCas9	negative selection	9422013
42722814	42722837	17	-	27260156	TC32	viability	AGCTGATCAATAACTATGATGGG	EZH1	ENSG00000108799	0.07325297278254417	[568]	[583,539,556,534]	1	hSpCas9	negative selection	9422014
42720369	42720392	17	+	27260156	TC32	viability	CCTCATCTGAGTACTGATTCAGG	EZH1	ENSG00000108799	0.5043267392023658	[1325]	[1628,1305,2635,1735]	8	hSpCas9	negative selection	9422015
42720272	42720295	17	-	27260156	TC32	viability	AGAAAGCGACATGCTATTGAAGG	EZH1	ENSG00000108799	-0.30485427147160793	[474]	[379,244,436,419]	-5	hSpCas9	negative selection	9486278
42722786	42722809	17	+	27260156	TC32	viability	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.05710430815381562	[639]	[759,378,724,698]	1	hSpCas9	negative selection	9486279
42727751	42727774	17	-	27260156	TC32	viability	GCTTTGCTAGGCTTTGTATGTGG	EZH1	ENSG00000108799	-0.09909308806833314	[573]	[442,309,689,665]	-2	hSpCas9	negative selection	9486280
42712388	42712411	17	-	27869803	HPAFII	viability after 27 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.7400932303005274	[416]	[465,282,NaN]	6	hSpCas9	negative selection	9560921
42713333	42713356	17	+	27869803	HPAFII	viability after 27 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-2.160427451439103	[360]	[66,21,NaN]	-8	hSpCas9	negative selection	9560922
42718466	42718489	17	+	27869803	HPAFII	viability after 27 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.9751525157591591	[188]	[73,30,NaN]	-6	hSpCas9	negative selection	9560923
42720366	42720389	17	-	27869803	HPAFII	viability after 27 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.5543686008230213	[112]	[4,69,NaN]	-4	hSpCas9	negative selection	9560924
42722786	42722809	17	+	27869803	HPAFII	viability after 27 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.1994259578020914	[323]	[274,487,NaN]	8	hSpCas9	negative selection	9560925
42727660	42727683	17	+	27869803	HPAFII	viability after 27 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.0639021339443072	[260]	[145,118,NaN]	0	hSpCas9	negative selection	9560926
42712388	42712411	17	-	27869803	HPAFII	viability after 15 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.7942406199445959	[416]	[1341,425,NaN]	8	hSpCas9	negative selection	9643370
42713333	42713356	17	+	27869803	HPAFII	viability after 15 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-0.7226075127730108	[360]	[215,246,NaN]	-6	hSpCas9	negative selection	9643371
42718466	42718489	17	+	27869803	HPAFII	viability after 15 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.984376116595351	[188]	[114,94,NaN]	-7	hSpCas9	negative selection	9643372
42720366	42720389	17	-	27869803	HPAFII	viability after 15 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.9199774550910877	[112]	[86,49,NaN]	-7	hSpCas9	negative selection	9643373
42722786	42722809	17	+	27869803	HPAFII	viability after 15 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.7282586113008271	[323]	[529,605,NaN]	7	hSpCas9	negative selection	9643374
42727660	42727683	17	+	27869803	HPAFII	viability after 15 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.47203434683806594	[260]	[504,316,NaN]	5	hSpCas9	negative selection	9643375
42712388	42712411	17	-	27869803	ASPC1	viability after 36 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.45199937097450027	[1281]	[517,273,231]	-4	hSpCas9	negative selection	9725819
42713333	42713356	17	+	27869803	ASPC1	viability after 36 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-0.2984882062646385	[998]	[198,295,329]	-3	hSpCas9	negative selection	9725820
42718466	42718489	17	+	27869803	ASPC1	viability after 36 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.3613979779294135	[469]	[203,321,124]	3	hSpCas9	negative selection	9725821
42720366	42720389	17	-	27869803	ASPC1	viability after 36 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.010457200486874152	[226]	[120,89,41]	0	hSpCas9	negative selection	9725822
42722786	42722809	17	+	27869803	ASPC1	viability after 36 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	-0.009197314149941516	[900]	[593,121,262]	0	hSpCas9	negative selection	9725823
42727660	42727683	17	+	27869803	ASPC1	viability after 36 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.7048504060064429	[793]	[708,454,263]	7	hSpCas9	negative selection	9725824
42712388	42712411	17	-	27869803	PATU8988S	viability after 35 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.425105753523229	[1041]	[338,285,NaN]	-4	hSpCas9	negative selection	9808268
42713333	42713356	17	+	27869803	PATU8988S	viability after 35 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.8857693407993131	[768]	[692,450,NaN]	8	hSpCas9	negative selection	9808269
42718466	42718489	17	+	27869803	PATU8988S	viability after 35 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-1.1951253711152738	[471]	[93,71,NaN]	-8	hSpCas9	negative selection	9808270
42720366	42720389	17	-	27869803	PATU8988S	viability after 35 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.07541025508997157	[216]	[129,53,NaN]	0	hSpCas9	negative selection	9808271
42722786	42722809	17	+	27869803	PATU8988S	viability after 35 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.4635719020826927	[956]	[527,534,NaN]	5	hSpCas9	negative selection	9808272
42727660	42727683	17	+	27869803	PATU8988S	viability after 35 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.14651587916823577	[688]	[375,237,NaN]	1	hSpCas9	negative selection	9808273
42712388	42712411	17	-	27869803	PATU8988S	viability after 31 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	-0.2024367860280507	[1041]	[240,513,NaN]	-2	hSpCas9	negative selection	9890717
42713333	42713356	17	+	27869803	PATU8988S	viability after 31 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	0.6441920557442516	[768]	[414,560,NaN]	7	hSpCas9	negative selection	9890718
42718466	42718489	17	+	27869803	PATU8988S	viability after 31 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.81844372898402	[471]	[122,85,NaN]	-7	hSpCas9	negative selection	9890719
42720366	42720389	17	-	27869803	PATU8988S	viability after 31 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.17909159527722496	[216]	[115,74,NaN]	2	hSpCas9	negative selection	9890720
42722786	42722809	17	+	27869803	PATU8988S	viability after 31 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	0.41579387190527717	[956]	[428,610,NaN]	5	hSpCas9	negative selection	9890721
42727660	42727683	17	+	27869803	PATU8988S	viability after 31 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	0.5420204571877684	[688]	[476,301,NaN]	6	hSpCas9	negative selection	9890722
42712388	42712411	17	-	27869803	HPAFII	viability after 35 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	1.0061861255181246	[416]	[471,369,NaN]	6	hSpCas9	negative selection	9973166
42713333	42713356	17	+	27869803	HPAFII	viability after 35 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-1.7935053148366598	[360]	[79,21,NaN]	-7	hSpCas9	negative selection	9973167
42718466	42718489	17	+	27869803	HPAFII	viability after 35 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.1568759951323857	[188]	[82,88,NaN]	-1	hSpCas9	negative selection	9973168
42720366	42720389	17	-	27869803	HPAFII	viability after 35 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-2.5247412994199334	[112]	[8,10,NaN]	-8	hSpCas9	negative selection	9973169
42722786	42722809	17	+	27869803	HPAFII	viability after 35 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.6042086261007964	[323]	[207,825,NaN]	9	hSpCas9	negative selection	9973170
42727660	42727683	17	+	27869803	HPAFII	viability after 35 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.4662704487973152	[260]	[81,110,NaN]	-3	hSpCas9	negative selection	9973171
42712388	42712411	17	-	27869803	HPAFII	viability after 31 days	CACCCTCGGAGCCTGTGGAATGG	EZH1	ENSG00000108799	0.7794166237760569	[416]	[472,323,NaN]	5	hSpCas9	negative selection	10055615
42713333	42713356	17	+	27869803	HPAFII	viability after 31 days	ACGACCAGAGCACTTGGAGCGGG	EZH1	ENSG00000108799	-4.5933218027045175	[360]	[5,10,NaN]	-9	hSpCas9	negative selection	10055616
42718466	42718489	17	+	27869803	HPAFII	viability after 31 days	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.7763379633815842	[188]	[37,87,NaN]	-5	hSpCas9	negative selection	10055617
42720366	42720389	17	-	27869803	HPAFII	viability after 31 days	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-1.5073739256643233	[112]	[17,26,NaN]	-7	hSpCas9	negative selection	10055618
42722786	42722809	17	+	27869803	HPAFII	viability after 31 days	TACCACTACCTTCTTCACCATGG	EZH1	ENSG00000108799	1.7517675310533294	[323]	[251,1004,NaN]	9	hSpCas9	negative selection	10055619
42727660	42727683	17	+	27869803	HPAFII	viability after 31 days	ACAGGCTTCATTGACTGAACAGG	EZH1	ENSG00000108799	-0.35776304921404356	[260]	[109,118,NaN]	-2	hSpCas9	negative selection	10055620
42720366	42720389	17	-	28162770	P31FUJ	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.466292334634157	[86]	[73]	-4	hSpCas9	negative selection	10152240
42713235	42713258	17	-	28162770	P31FUJ	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-1.183892603933432	[144]	[74]	-7	hSpCas9	negative selection	10152241
42718036	42718059	17	+	28162770	P31FUJ	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-0.8848789009940723	[21]	[13]	-6	hSpCas9	negative selection	10152242
42713256	42713279	17	-	28162770	P31FUJ	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	-0.5495376300814184	[207]	[166]	-4	hSpCas9	negative selection	10152243
42712381	42712404	17	-	28162770	P31FUJ	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.24405130246622098	[216]	[301]	2	hSpCas9	negative selection	10152244
42706150	42706173	17	+	28162770	P31FUJ	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.21142855362181168	[66]	[67]	-2	hSpCas9	negative selection	10152245
42706048	42706071	17	-	28162770	P31FUJ	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-1.5353649744348097	[36]	[14]	-7	hSpCas9	negative selection	10152246
42724323	42724346	17	+	28162770	P31FUJ	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	1.0810885714075653	[71]	[178]	9	hSpCas9	negative selection	10152247
42718524	42718547	17	-	28162770	P31FUJ	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.2526246227558633	[499]	[699]	2	hSpCas9	negative selection	10152248
42718466	42718489	17	+	28162770	P31FUJ	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.15222272579802554	[339]	[443]	1	hSpCas9	negative selection	10152249
42720366	42720389	17	-	28162770	TF1	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10321606
42713235	42713258	17	-	28162770	TF1	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10321607
42718036	42718059	17	+	28162770	TF1	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10321608
42713256	42713279	17	-	28162770	TF1	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10321609
42712381	42712404	17	-	28162770	TF1	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10321610
42706150	42706173	17	+	28162770	TF1	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10321611
42706048	42706071	17	-	28162770	TF1	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10321612
42724323	42724346	17	+	28162770	TF1	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10321613
42718524	42718547	17	-	28162770	TF1	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	NaN	[NaN]	[313]	1	hSpCas9	negative selection	10321614
42718466	42718489	17	+	28162770	TF1	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	NaN	[NaN]	[331]	1	hSpCas9	negative selection	10321615
42720366	42720389	17	-	28162770	SKM1	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.45426991352151846	[30]	[39]	-4	hSpCas9	negative selection	10490972
42713235	42713258	17	-	28162770	SKM1	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-1.6644604210355256	[51]	[28]	-8	hSpCas9	negative selection	10490973
42718036	42718059	17	+	28162770	SKM1	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-3.4069641987431614	[5]	[0]	-9	hSpCas9	negative selection	10490974
42713256	42713279	17	-	28162770	SKM1	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.9853532240355987	[55]	[195]	8	hSpCas9	negative selection	10490975
42712381	42712404	17	-	28162770	SKM1	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.02367015558670066	[68]	[123]	0	hSpCas9	negative selection	10490976
42706150	42706173	17	+	28162770	SKM1	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	0.9369902024741996	[12]	[43]	8	hSpCas9	negative selection	10490977
42706048	42706071	17	-	28162770	SKM1	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	1.307281318922961	[7]	[34]	9	hSpCas9	negative selection	10490978
42724323	42724346	17	+	28162770	SKM1	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	0.25199888342177124	[18]	[39]	2	hSpCas9	negative selection	10490979
42718524	42718547	17	-	28162770	SKM1	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.6046237755320499	[92]	[249]	6	hSpCas9	negative selection	10490980
42718466	42718489	17	+	28162770	SKM1	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.07476776840197219	[83]	[140]	0	hSpCas9	negative selection	10490981
42720366	42720389	17	-	28162770	SKM1	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.45426991352151846	[30]	[39]	-4	hSpCas9	negative selection	10660338
42713235	42713258	17	-	28162770	SKM1	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-1.6644604210355256	[51]	[28]	-8	hSpCas9	negative selection	10660339
42718036	42718059	17	+	28162770	SKM1	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-3.4069641987431614	[5]	[0]	-9	hSpCas9	negative selection	10660340
42713256	42713279	17	-	28162770	SKM1	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.9853532240355987	[55]	[195]	8	hSpCas9	negative selection	10660341
42712381	42712404	17	-	28162770	SKM1	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.02367015558670066	[68]	[123]	0	hSpCas9	negative selection	10660342
42706150	42706173	17	+	28162770	SKM1	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	0.9369902024741996	[12]	[43]	8	hSpCas9	negative selection	10660343
42706048	42706071	17	-	28162770	SKM1	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	1.307281318922961	[7]	[34]	9	hSpCas9	negative selection	10660344
42724323	42724346	17	+	28162770	SKM1	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	0.25199888342177124	[18]	[39]	2	hSpCas9	negative selection	10660345
42718524	42718547	17	-	28162770	SKM1	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.6046237755320499	[92]	[249]	6	hSpCas9	negative selection	10660346
42718466	42718489	17	+	28162770	SKM1	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.07476776840197219	[83]	[140]	0	hSpCas9	negative selection	10660347
42720366	42720389	17	-	28162770	PL21	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.5368259796768862	[69]	[20]	-4	hSpCas9	negative selection	10829704
42713235	42713258	17	-	28162770	PL21	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-2.7204259180162746	[105]	[6]	-9	hSpCas9	negative selection	10829705
42718036	42718059	17	+	28162770	PL21	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	0.25672314285568776	[24]	[12]	2	hSpCas9	negative selection	10829706
42713256	42713279	17	-	28162770	PL21	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	1.4903954890581381	[174]	[213]	9	hSpCas9	negative selection	10829707
42712381	42712404	17	-	28162770	PL21	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	-0.1763343035656359	[282]	[108]	-1	hSpCas9	negative selection	10829708
42706150	42706173	17	+	28162770	PL21	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.04378596839676918	[89]	[37]	0	hSpCas9	negative selection	10829709
42706048	42706071	17	-	28162770	PL21	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-3.2592920041479774	[21]	[0]	-9	hSpCas9	negative selection	10829710
42724323	42724346	17	+	28162770	PL21	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	1.1626649090706573	[77]	[75]	8	hSpCas9	negative selection	10829711
42718524	42718547	17	-	28162770	PL21	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.6866497750626891	[391]	[105]	-5	hSpCas9	negative selection	10829712
42718466	42718489	17	+	28162770	PL21	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.01251261131354875	[204]	[89]	0	hSpCas9	negative selection	10829713
42720366	42720389	17	-	28162770	P31FUJ	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.466292334634157	[86]	[73]	-4	hSpCas9	negative selection	10999070
42713235	42713258	17	-	28162770	P31FUJ	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-1.183892603933432	[144]	[74]	-7	hSpCas9	negative selection	10999071
42718036	42718059	17	+	28162770	P31FUJ	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-0.8848789009940723	[21]	[13]	-6	hSpCas9	negative selection	10999072
42713256	42713279	17	-	28162770	P31FUJ	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	-0.5495376300814184	[207]	[166]	-4	hSpCas9	negative selection	10999073
42712381	42712404	17	-	28162770	P31FUJ	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.24405130246622098	[216]	[301]	2	hSpCas9	negative selection	10999074
42706150	42706173	17	+	28162770	P31FUJ	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.21142855362181168	[66]	[67]	-2	hSpCas9	negative selection	10999075
42706048	42706071	17	-	28162770	P31FUJ	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-1.5353649744348097	[36]	[14]	-7	hSpCas9	negative selection	10999076
42724323	42724346	17	+	28162770	P31FUJ	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	1.0810885714075653	[71]	[178]	9	hSpCas9	negative selection	10999077
42718524	42718547	17	-	28162770	P31FUJ	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.2526246227558633	[499]	[699]	2	hSpCas9	negative selection	10999078
42718466	42718489	17	+	28162770	P31FUJ	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.15222272579802554	[339]	[443]	1	hSpCas9	negative selection	10999079
42720366	42720389	17	-	28162770	OCIAML5	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.1216736306212769	[43]	[72]	-1	hSpCas9	negative selection	11168436
42713235	42713258	17	-	28162770	OCIAML5	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-1.9531526959783116	[132]	[61]	-8	hSpCas9	negative selection	11168437
42718036	42718059	17	+	28162770	OCIAML5	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	1.0808192332774658	[10]	[41]	8	hSpCas9	negative selection	11168438
42713256	42713279	17	-	28162770	OCIAML5	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	1.2273678966304078	[52]	[223]	9	hSpCas9	negative selection	11168439
42712381	42712404	17	-	28162770	OCIAML5	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.881097453142353	[113]	[378]	7	hSpCas9	negative selection	11168440
42706150	42706173	17	+	28162770	OCIAML5	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	0.6771864972708715	[43]	[126]	6	hSpCas9	negative selection	11168441
42706048	42706071	17	-	28162770	OCIAML5	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-2.299525547835218	[29]	[10]	-8	hSpCas9	negative selection	11168442
42724323	42724346	17	+	28162770	OCIAML5	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	0.8812877697498304	[39]	[132]	7	hSpCas9	negative selection	11168443
42718524	42718547	17	-	28162770	OCIAML5	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.08591250917024351	[273]	[465]	0	hSpCas9	negative selection	11168444
42718466	42718489	17	+	28162770	OCIAML5	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.732895929857159	[144]	[434]	6	hSpCas9	negative selection	11168445
42720366	42720389	17	-	28162770	EOL1	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.5544361431732069	[136]	[105]	5	hSpCas9	negative selection	11337802
42713235	42713258	17	-	28162770	EOL1	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-0.9234491349844152	[215]	[59]	-6	hSpCas9	negative selection	11337803
42718036	42718059	17	+	28162770	EOL1	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	0.12808116565566685	[32]	[18]	1	hSpCas9	negative selection	11337804
42713256	42713279	17	-	28162770	EOL1	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.8238537719510615	[355]	[331]	7	hSpCas9	negative selection	11337805
42712381	42712404	17	-	28162770	EOL1	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	-1.05945174973575	[537]	[135]	-6	hSpCas9	negative selection	11337806
42706150	42706173	17	+	28162770	EOL1	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.503313768065893	[112]	[41]	-4	hSpCas9	negative selection	11337807
42706048	42706071	17	-	28162770	EOL1	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-1.7193084182041902	[24]	[3]	-8	hSpCas9	negative selection	11337808
42724323	42724346	17	+	28162770	EOL1	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	2.041731310940874	[64]	[140]	9	hSpCas9	negative selection	11337809
42718524	42718547	17	-	28162770	EOL1	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.7613436380014024	[443]	[137]	-5	hSpCas9	negative selection	11337810
42718466	42718489	17	+	28162770	EOL1	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	1.0325070197064543	[295]	[318]	8	hSpCas9	negative selection	11337811
42720366	42720389	17	-	28162770	MOLM13	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.4342632950572767	[113]	[60]	-3	hSpCas9	negative selection	11507168
42713235	42713258	17	-	28162770	MOLM13	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-2.3883751409939715	[209]	[28]	-8	hSpCas9	negative selection	11507169
42718036	42718059	17	+	28162770	MOLM13	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-1.8540387133427836	[24]	[4]	-7	hSpCas9	negative selection	11507170
42713256	42713279	17	-	28162770	MOLM13	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	-0.08594322173240658	[297]	[202]	0	hSpCas9	negative selection	11507171
42712381	42712404	17	-	28162770	MOLM13	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.6242576675510306	[296]	[330]	5	hSpCas9	negative selection	11507172
42706150	42706173	17	+	28162770	MOLM13	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.030229859228819933	[136]	[96]	0	hSpCas9	negative selection	11507173
42706048	42706071	17	-	28162770	MOLM13	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-5.023963714785096	[44]	[0]	-9	hSpCas9	negative selection	11507174
42724323	42724346	17	+	28162770	MOLM13	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-0.6757014720842711	[94]	[42]	-4	hSpCas9	negative selection	11507175
42718524	42718547	17	-	28162770	MOLM13	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.782747419156993	[532]	[223]	-4	hSpCas9	negative selection	11507176
42718466	42718489	17	+	28162770	MOLM13	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.14759237223614463	[441]	[353]	1	hSpCas9	negative selection	11507177
42720366	42720389	17	-	28162770	HEL	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	0.7023276282901568	[165]	[172]	6	hSpCas9	negative selection	11676534
42713235	42713258	17	-	28162770	HEL	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-1.9307280298829697	[124]	[20]	-7	hSpCas9	negative selection	11676535
42718036	42718059	17	+	28162770	HEL	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	2.668273924107494	[13]	[56]	9	hSpCas9	negative selection	11676536
42713256	42713279	17	-	28162770	HEL	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.685968884061926	[262]	[270]	6	hSpCas9	negative selection	11676537
42712381	42712404	17	-	28162770	HEL	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	-0.578231514266893	[337]	[144]	-4	hSpCas9	negative selection	11676538
42706150	42706173	17	+	28162770	HEL	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-0.25469143435909536	[94]	[50]	-2	hSpCas9	negative selection	11676539
42706048	42706071	17	-	28162770	HEL	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-1.579653589336091	[55]	[11]	-7	hSpCas9	negative selection	11676540
42724323	42724346	17	+	28162770	HEL	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-0.24478643874123063	[73]	[39]	-2	hSpCas9	negative selection	11676541
42718524	42718547	17	-	28162770	HEL	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.33788425047193604	[419]	[339]	3	hSpCas9	negative selection	11676542
42718466	42718489	17	+	28162770	HEL	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.4929162673572092	[311]	[141]	-3	hSpCas9	negative selection	11676543
42720366	42720389	17	-	28162770	MV411	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.1781748883456615	[63]	[121]	9	hSpCas9	negative selection	11845900
42713235	42713258	17	-	28162770	MV411	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-2.811456138270793	[174]	[20]	-9	hSpCas9	negative selection	11845901
42718036	42718059	17	+	28162770	MV411	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-1.074490544104587	[4]	[1]	-6	hSpCas9	negative selection	11845902
42713256	42713279	17	-	28162770	MV411	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.5693656456701377	[183]	[229]	5	hSpCas9	negative selection	11845903
42712381	42712404	17	-	28162770	MV411	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.2775575391591107	[236]	[241]	2	hSpCas9	negative selection	11845904
42706150	42706173	17	+	28162770	MV411	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-1.267135622046983	[59]	[20]	-7	hSpCas9	negative selection	11845905
42706048	42706071	17	-	28162770	MV411	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-2.2671356220469834	[39]	[6]	-8	hSpCas9	negative selection	11845906
42724323	42724346	17	+	28162770	MV411	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	0.11208569788788902	[66]	[60]	1	hSpCas9	negative selection	11845907
42718524	42718547	17	-	28162770	MV411	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.5797258523550092	[274]	[154]	-4	hSpCas9	negative selection	11845908
42718466	42718489	17	+	28162770	MV411	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.009054009184246481	[263]	[220]	0	hSpCas9	negative selection	11845909
42720366	42720389	17	-	28162770	MONOMAC1	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.0768858749169765	[54]	[132]	8	hSpCas9	negative selection	12015266
42713235	42713258	17	-	28162770	MONOMAC1	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-0.4784497822082022	[78]	[64]	-4	hSpCas9	negative selection	12015267
42718036	42718059	17	+	28162770	MONOMAC1	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	-1.78199934778071	[8]	[2]	-8	hSpCas9	negative selection	12015268
42713256	42713279	17	-	28162770	MONOMAC1	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.4094267228725247	[110]	[168]	4	hSpCas9	negative selection	12015269
42712381	42712404	17	-	28162770	MONOMAC1	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	0.08863536245397194	[136]	[166]	0	hSpCas9	negative selection	12015270
42706150	42706173	17	+	28162770	MONOMAC1	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	0.0966943559971567	[30]	[37]	1	hSpCas9	negative selection	12015271
42706048	42706071	17	-	28162770	MONOMAC1	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-0.7819993477807099	[23]	[15]	-6	hSpCas9	negative selection	12015272
42724323	42724346	17	+	28162770	MONOMAC1	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-0.29832018289673545	[58]	[54]	-3	hSpCas9	negative selection	12015273
42718524	42718547	17	-	28162770	MONOMAC1	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	-0.039853514508823684	[277]	[309]	0	hSpCas9	negative selection	12015274
42718466	42718489	17	+	28162770	MONOMAC1	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	-0.05336648638811714	[190]	[210]	0	hSpCas9	negative selection	12015275
42720366	42720389	17	-	28162770	OCIAML2	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	1.5393542633304609	[8]	[144]	9	hSpCas9	negative selection	12184632
42713235	42713258	17	-	28162770	OCIAML2	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-2.333126301492226	[29]	[32]	-8	hSpCas9	negative selection	12184633
42718036	42718059	17	+	28162770	OCIAML2	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	1.5293701747578385	[0]	[15]	9	hSpCas9	negative selection	12184634
42713256	42713279	17	-	28162770	OCIAML2	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.7290425195942031	[31]	[293]	7	hSpCas9	negative selection	12184635
42712381	42712404	17	-	28162770	OCIAML2	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	-0.07556702572458346	[49]	[262]	0	hSpCas9	negative selection	12184636
42706150	42706173	17	+	28162770	OCIAML2	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	0.014797001928080533	[9]	[55]	0	hSpCas9	negative selection	12184637
42706048	42706071	17	-	28162770	OCIAML2	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	-1.2779847472997656	[6]	[15]	-7	hSpCas9	negative selection	12184638
42724323	42724346	17	+	28162770	OCIAML2	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-0.16806705522172982	[14]	[73]	-1	hSpCas9	negative selection	12184639
42718524	42718547	17	-	28162770	OCIAML2	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.41536554605500753	[50]	[376]	4	hSpCas9	negative selection	12184640
42718466	42718489	17	+	28162770	OCIAML2	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.29018251087841257	[44]	[304]	2	hSpCas9	negative selection	12184641
42720366	42720389	17	-	28162770	OCIAML3	viability	GAATCAGTACTCAGATGAGGAGG	EZH1	ENSG00000108799	-0.3309732344903693	[14]	[35]	-3	hSpCas9	negative selection	12353998
42713235	42713258	17	-	28162770	OCIAML3	viability	GGAGACAGTGACAGGGACACAGG	EZH1	ENSG00000108799	-0.24608433690385623	[32]	[83]	-2	hSpCas9	negative selection	12353999
42718036	42718059	17	+	28162770	OCIAML3	viability	GCGTTTATATACATTAGGGGTGG	EZH1	ENSG00000108799	2.3832722831757533	[3]	[62]	9	hSpCas9	negative selection	12354000
42713256	42713279	17	-	28162770	OCIAML3	viability	GCTGTGGCTGAGACTAAAGAAGG	EZH1	ENSG00000108799	0.5557394791805188	[63]	[283]	5	hSpCas9	negative selection	12354001
42712381	42712404	17	-	28162770	OCIAML3	viability	GGAGCCTGTGGAATGGACTGGGG	EZH1	ENSG00000108799	-0.22924334752654285	[72]	[187]	-2	hSpCas9	negative selection	12354002
42706150	42706173	17	+	28162770	OCIAML3	viability	GGGTCTTACAGCGACAGCCAGGG	EZH1	ENSG00000108799	-1.8894635238503343	[26]	[21]	-8	hSpCas9	negative selection	12354003
42706048	42706071	17	-	28162770	OCIAML3	viability	AGAGCACTGGGACTGCAAGGTGG	EZH1	ENSG00000108799	0.47638168756723465	[4]	[20]	4	hSpCas9	negative selection	12354004
42724323	42724346	17	+	28162770	OCIAML3	viability	AGGGGACCAGGAATACATGATGG	EZH1	ENSG00000108799	-0.5496135209657096	[15]	[32]	-4	hSpCas9	negative selection	12354005
42718524	42718547	17	-	28162770	OCIAML3	viability	CCAATGCCAAGTCTGTGCAGCGG	EZH1	ENSG00000108799	0.5055280332267513	[69]	[299]	5	hSpCas9	negative selection	12354006
42718466	42718489	17	+	28162770	OCIAML3	viability	AGTCGTATTTAAAGCAGCGCCGG	EZH1	ENSG00000108799	0.1221993936752458	[76]	[252]	1	hSpCas9	negative selection	12354007