Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2146
• Symbol:EZH2
• Description:enhancer of zeste 2 polycomb repressive complex 2 subunit

DataSource: http://genomecrispr.dkfz.de/#!/results/EZH2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
148817935	148817958	7	-	26472758	Jiyoye	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-0.13644632383438338	[85]	[58]	-1	hSpCas9	negative selection	52674
148817978	148818001	7	+	26472758	Jiyoye	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.1495902273846309	[227]	[154]	-1	hSpCas9	negative selection	52675
148846524	148846547	7	-	26472758	Jiyoye	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.5635769388484404	[130]	[145]	4	hSpCas9	negative selection	52676
148817237	148817260	7	+	26472758	Jiyoye	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-0.5928246184941268	[15]	[7]	-4	hSpCas9	negative selection	52677
148809363	148809386	7	-	26472758	Jiyoye	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	3.2145303035634774	[13]	[97]	9	hSpCas9	negative selection	52678
148847268	148847291	7	-	26472758	Jiyoye	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	4.902586297248737	[8]	[202]	9	hSpCas9	negative selection	52679
148846495	148846518	7	+	26472758	Jiyoye	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.36636482755948696	[252]	[147]	-3	hSpCas9	negative selection	52680
148828752	148828775	7	-	26472758	Jiyoye	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.3481395225392247	[210]	[124]	-2	hSpCas9	negative selection	52682
148828739	148828762	7	-	26472758	Jiyoye	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-1.3726988041296238	[181]	[52]	-7	hSpCas9	negative selection	52683
148818031	148818054	7	-	26472758	Jiyoye	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-0.2708965236067642	[47]	[29]	-2	hSpCas9	negative selection	52684
148817935	148817958	7	-	26472758	KBM7	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-1.5410820554267288	[256,214]	[47,28]	-8	hSpCas9	negative selection	243792
148817978	148818001	7	+	26472758	KBM7	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.43737992552712207	[795,771]	[251,291]	-4	hSpCas9	negative selection	243793
148846524	148846547	7	-	26472758	KBM7	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	-0.30350903852664496	[733,585]	[300,203]	-3	hSpCas9	negative selection	243794
148817237	148817260	7	+	26472758	KBM7	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-2.1823932873936167	[78,61]	[11,2]	-8	hSpCas9	negative selection	243795
148809363	148809386	7	-	26472758	KBM7	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-5.15243325020474	[614,382]	[6,5]	-9	hSpCas9	negative selection	243796
148847268	148847291	7	-	26472758	KBM7	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.14993460949044024	[413,269]	[185,165]	1	hSpCas9	negative selection	243797
148846495	148846518	7	+	26472758	KBM7	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-1.0869349032592448	[923,968]	[200,219]	-7	hSpCas9	negative selection	243798
148828752	148828775	7	-	26472758	KBM7	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.35949761633280664	[614,396]	[167,194]	-3	hSpCas9	negative selection	243800
148828739	148828762	7	-	26472758	KBM7	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.7076055891057769	[716,534]	[141,210]	-5	hSpCas9	negative selection	243801
148818031	148818054	7	-	26472758	KBM7	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-2.902597981795992	[229,145]	[18,4]	-9	hSpCas9	negative selection	243802
148817935	148817958	7	-	26472758	Raji	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-1.4555526590175574	[129]	[10]	-7	hSpCas9	negative selection	434910
148817978	148818001	7	+	26472758	Raji	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.36785859811115984	[366]	[65]	-3	hSpCas9	negative selection	434911
148846524	148846547	7	-	26472758	Raji	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	-0.6816705699410609	[234]	[33]	-5	hSpCas9	negative selection	434912
148817237	148817260	7	+	26472758	Raji	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-0.6088234986258096	[45]	[6]	-5	hSpCas9	negative selection	434913
148809363	148809386	7	-	26472758	Raji	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-1.8330596199459457	[260]	[16]	-8	hSpCas9	negative selection	434914
148847268	148847291	7	-	26472758	Raji	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	-0.8926164646264004	[215]	[26]	-6	hSpCas9	negative selection	434915
148846495	148846518	7	+	26472758	Raji	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-1.1115698019960774	[418]	[44]	-7	hSpCas9	negative selection	434916
148828752	148828775	7	-	26472758	Raji	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.18539821385424646	[244]	[49]	-1	hSpCas9	negative selection	434918
148828739	148828762	7	-	26472758	Raji	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.9026005531990224	[289]	[35]	-6	hSpCas9	negative selection	434919
148818031	148818054	7	-	26472758	Raji	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-4.187237213518028	[156]	[1]	-9	hSpCas9	negative selection	434920
148817935	148817958	7	-	26472758	K562	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-2.7307778813329806	[172]	[21]	-8	hSpCas9	negative selection	626028
148817978	148818001	7	+	26472758	K562	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.32810666981648673	[692]	[465]	-2	hSpCas9	negative selection	626029
148846524	148846547	7	-	26472758	K562	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.969965305426957	[481]	[796]	7	hSpCas9	negative selection	626030
148817237	148817260	7	+	26472758	K562	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-5.31017012401119	[46]	[0]	-9	hSpCas9	negative selection	626031
148809363	148809386	7	-	26472758	K562	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-3.487885489129896	[411]	[30]	-8	hSpCas9	negative selection	626032
148847268	148847291	7	-	26472758	K562	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.19537054642165647	[358]	[346]	1	hSpCas9	negative selection	626033
148846495	148846518	7	+	26472758	K562	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	0.7851963013793877	[861]	[1253]	6	hSpCas9	negative selection	626034
148828752	148828775	7	-	26472758	K562	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.22295023569991182	[523]	[378]	-1	hSpCas9	negative selection	626036
148828739	148828762	7	-	26472758	K562	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.3110999951622276	[484]	[329]	-2	hSpCas9	negative selection	626037
148818031	148818054	7	-	26472758	K562	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	0.4153515496463478	[158]	[178]	3	hSpCas9	negative selection	626038
148819603	148819626	7	+	26627737	DLD1	viability	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-1.0488738996282994	[271]	[20,54,46]	-7	hSpCas9	negative selection	835423
148827230	148827253	7	+	26627737	DLD1	viability	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-2.117529657099012	[304]	[12,11,37]	-9	hSpCas9	negative selection	835424
148828739	148828762	7	-	26627737	DLD1	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.5220361753217346	[182]	[64,28,26]	-5	hSpCas9	negative selection	835425
148836827	148836850	7	-	26627737	DLD1	viability	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.384129312613237	[162]	[62,42,14]	-4	hSpCas9	negative selection	835426
148846469	148846492	7	-	26627737	DLD1	viability	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.7343248819904424	[521]	[110,74,105]	-6	hSpCas9	negative selection	835427
148847243	148847266	7	+	26627737	DLD1	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.3149963993981463	[874]	[344,366,313]	3	hSpCas9	negative selection	835428
148819603	148819626	7	+	26627737	GBM cells	viability after 5 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-0.35824396461143904	[97]	[29,51]	-5	hSpCas9	negative selection	917738
148827230	148827253	7	+	26627737	GBM cells	viability after 5 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.6136401303074205	[203]	[66,75]	-7	hSpCas9	negative selection	917739
148828739	148828762	7	-	26627737	GBM cells	viability after 5 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.2659713452627077	[106]	[67,69]	4	hSpCas9	negative selection	917740
148836827	148836850	7	-	26627737	GBM cells	viability after 5 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.2800040422411918	[128]	[80,86]	4	hSpCas9	negative selection	917741
148846469	148846492	7	-	26627737	GBM cells	viability after 5 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.03752099633684827	[221]	[97,133]	0	hSpCas9	negative selection	917742
148847243	148847266	7	+	26627737	GBM cells	viability after 5 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.45582795795493714	[553]	[405,408]	6	hSpCas9	negative selection	917743
148819603	148819626	7	+	26627737	GBM cells	viability after 13 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-0.4358254395440222	[97]	[35,41]	-5	hSpCas9	negative selection	1000053
148827230	148827253	7	+	26627737	GBM cells	viability after 13 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-1.440032987319785	[203]	[42,38]	-9	hSpCas9	negative selection	1000054
148828739	148828762	7	-	26627737	GBM cells	viability after 13 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.06754253816209754	[106]	[83,41]	0	hSpCas9	negative selection	1000055
148836827	148836850	7	-	26627737	GBM cells	viability after 13 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.3976627545942554	[128]	[164,32]	5	hSpCas9	negative selection	1000056
148846469	148846492	7	-	26627737	GBM cells	viability after 13 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.21423990738884577	[221]	[163,119]	2	hSpCas9	negative selection	1000057
148847243	148847266	7	+	26627737	GBM cells	viability after 13 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.19598191841162782	[553]	[372,320]	2	hSpCas9	negative selection	1000058
148819603	148819626	7	+	26627737	GBM cells	viability after 21 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-2.5860847046068787	[97]	[11,5]	-9	hSpCas9	negative selection	1082368
148827230	148827253	7	+	26627737	GBM cells	viability after 21 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-1.8688315399202258	[203]	[33,26]	-8	hSpCas9	negative selection	1082369
148828739	148828762	7	-	26627737	GBM cells	viability after 21 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.304259369751273	[106]	[56,37]	-3	hSpCas9	negative selection	1082370
148836827	148836850	7	-	26627737	GBM cells	viability after 21 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.3032635896480329	[128]	[86,85]	3	hSpCas9	negative selection	1082371
148846469	148846492	7	-	26627737	GBM cells	viability after 21 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.15647773433941553	[221]	[114,101]	-1	hSpCas9	negative selection	1082372
148847243	148847266	7	+	26627737	GBM cells	viability after 21 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.22195535544189404	[553]	[361,340]	2	hSpCas9	negative selection	1082373
148819603	148819626	7	+	26627737	RPE1	viability after 9 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	1.241602246339034	[231]	[138,213]	7	hSpCas9	negative selection	1164683
148827230	148827253	7	+	26627737	RPE1	viability after 9 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.4391039662637283	[452]	[94,116]	-3	hSpCas9	negative selection	1164684
148828739	148828762	7	-	26627737	RPE1	viability after 9 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.4425562514647384	[662]	[81,243]	-3	hSpCas9	negative selection	1164685
148836827	148836850	7	-	26627737	RPE1	viability after 9 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.24484125168866366	[394]	[225,43]	1	hSpCas9	negative selection	1164686
148846469	148846492	7	-	26627737	RPE1	viability after 9 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.40145035250899547	[1038]	[192,314]	-3	hSpCas9	negative selection	1164687
148847243	148847266	7	+	26627737	RPE1	viability after 9 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.2598717085550937	[1285]	[785,1193]	7	hSpCas9	negative selection	1164688
148819603	148819626	7	+	26627737	RPE1	viability after 12 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	1.4255323489102092	[231]	[96,241]	7	hSpCas9	negative selection	1246998
148827230	148827253	7	+	26627737	RPE1	viability after 12 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	0.07820832335095229	[452]	[127,128]	0	hSpCas9	negative selection	1246999
148828739	148828762	7	-	26627737	RPE1	viability after 12 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.5777852372216236	[662]	[79,160]	-4	hSpCas9	negative selection	1247000
148836827	148836850	7	-	26627737	RPE1	viability after 12 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.3157331988996477	[394]	[202,56]	2	hSpCas9	negative selection	1247001
148846469	148846492	7	-	26627737	RPE1	viability after 12 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-1.0572421016349036	[1038]	[155,110]	-6	hSpCas9	negative selection	1247002
148847243	148847266	7	+	26627737	RPE1	viability after 12 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.1056531362781161	[1285]	[709,778]	6	hSpCas9	negative selection	1247003
148819603	148819626	7	+	26627737	RPE1	viability after 15 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.2866340731499293	[231]	[48,109]	1	hSpCas9	negative selection	1329313
148827230	148827253	7	+	26627737	RPE1	viability after 15 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.14792070973141525	[452]	[134,96]	-1	hSpCas9	negative selection	1329314
148828739	148828762	7	-	26627737	RPE1	viability after 15 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.7579653129215063	[662]	[31,186]	-5	hSpCas9	negative selection	1329315
148836827	148836850	7	-	26627737	RPE1	viability after 15 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.8920162140939418	[394]	[355,63]	5	hSpCas9	negative selection	1329316
148846469	148846492	7	-	26627737	RPE1	viability after 15 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-1.3543939650114614	[1038]	[145,84]	-7	hSpCas9	negative selection	1329317
148847243	148847266	7	+	26627737	RPE1	viability after 15 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.0835678568112104	[1285]	[829,713]	6	hSpCas9	negative selection	1329318
148819603	148819626	7	+	26627737	RPE1	viability after 18 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.04741277536485078	[231]	[55,73]	0	hSpCas9	negative selection	1411628
148827230	148827253	7	+	26627737	RPE1	viability after 18 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.2887492179820491	[452]	[43,159]	-2	hSpCas9	negative selection	1411629
148828739	148828762	7	-	26627737	RPE1	viability after 18 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.4609341818531656	[662]	[85,176]	-3	hSpCas9	negative selection	1411630
148836827	148836850	7	-	26627737	RPE1	viability after 18 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.03133379563417382	[394]	[156,47]	0	hSpCas9	negative selection	1411631
148846469	148846492	7	-	26627737	RPE1	viability after 18 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.43008324353609656	[1038]	[123,297]	-3	hSpCas9	negative selection	1411632
148847243	148847266	7	+	26627737	RPE1	viability after 18 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.190954143500985	[1285]	[699,890]	6	hSpCas9	negative selection	1411633
148819603	148819626	7	+	26627737	HeLa	viability after 8 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.9542021263400252	[157]	[189,101,120]	7	hSpCas9	negative selection	1493943
148827230	148827253	7	+	26627737	HeLa	viability after 8 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.35559591643113886	[341]	[76,142,119]	-3	hSpCas9	negative selection	1493944
148828739	148828762	7	-	26627737	HeLa	viability after 8 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.3749062134033372	[142]	[86,68,86]	3	hSpCas9	negative selection	1493945
148836827	148836850	7	-	26627737	HeLa	viability after 8 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.2785563950276162	[304]	[150,85,100]	-3	hSpCas9	negative selection	1493946
148846469	148846492	7	-	26627737	HeLa	viability after 8 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.07809037074435007	[322]	[219,138,104]	0	hSpCas9	negative selection	1493947
148847243	148847266	7	+	26627737	HeLa	viability after 8 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.1466659222440072	[1247]	[554,575,363]	-1	hSpCas9	negative selection	1493948
148819603	148819626	7	+	26627737	HeLa	viability after 12 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.9788555493250382	[157]	[136,159,85]	7	hSpCas9	negative selection	1576258
148827230	148827253	7	+	26627737	HeLa	viability after 12 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.2689460966090771	[341]	[75,104,170]	-2	hSpCas9	negative selection	1576259
148828739	148828762	7	-	26627737	HeLa	viability after 12 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.5084426275948093	[142]	[122,39,94]	4	hSpCas9	negative selection	1576260
148836827	148836850	7	-	26627737	HeLa	viability after 12 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.10282412612632319	[304]	[298,95,19]	0	hSpCas9	negative selection	1576261
148846469	148846492	7	-	26627737	HeLa	viability after 12 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.7224889116271825	[322]	[217,273,162]	6	hSpCas9	negative selection	1576262
148847243	148847266	7	+	26627737	HeLa	viability after 12 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.1523599485153433	[1247]	[804,500,427]	1	hSpCas9	negative selection	1576263
148819603	148819626	7	+	26627737	HeLa	viability after 15 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	1.6387930832475552	[157]	[154,227,219]	9	hSpCas9	negative selection	1658573
148827230	148827253	7	+	26627737	HeLa	viability after 15 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.0020161966619727245	[341]	[42,167,212]	0	hSpCas9	negative selection	1658574
148828739	148828762	7	-	26627737	HeLa	viability after 15 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.5122705683122809	[142]	[120,63,61]	4	hSpCas9	negative selection	1658575
148836827	148836850	7	-	26627737	HeLa	viability after 15 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.1231122840548115	[304]	[93,173,70]	-1	hSpCas9	negative selection	1658576
148846469	148846492	7	-	26627737	HeLa	viability after 15 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.2228357882780011	[322]	[143,168,146]	2	hSpCas9	negative selection	1658577
148847243	148847266	7	+	26627737	HeLa	viability after 15 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.1177486700474728	[1247]	[510,583,559]	1	hSpCas9	negative selection	1658578
148819603	148819626	7	+	26627737	HeLa	viability after 18 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	1.6680001101232698	[157]	[106,194,219]	9	hSpCas9	negative selection	1740888
148827230	148827253	7	+	26627737	HeLa	viability after 18 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.0016867576400219353	[341]	[28,138,212]	0	hSpCas9	negative selection	1740889
148828739	148828762	7	-	26627737	HeLa	viability after 18 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.5106439320032278	[142]	[80,52,61]	4	hSpCas9	negative selection	1740890
148836827	148836850	7	-	26627737	HeLa	viability after 18 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.21671897183921063	[304]	[49,142,70]	-2	hSpCas9	negative selection	1740891
148846469	148846492	7	-	26627737	HeLa	viability after 18 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.18479246539013905	[322]	[91,135,146]	1	hSpCas9	negative selection	1740892
148847243	148847266	7	+	26627737	HeLa	viability after 18 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.11219756641227341	[1247]	[347,471,559]	1	hSpCas9	negative selection	1740893
148819603	148819626	7	+	26627737	HCT116	viability after 6 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.8901893062638444	[385]	[96,120]	5	hSpCas9	negative selection	1823203
148827230	148827253	7	+	26627737	HCT116	viability after 6 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	0.021658282391025296	[747]	[304,16]	0	hSpCas9	negative selection	1823204
148828739	148828762	7	-	26627737	HCT116	viability after 6 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.11822023681584115	[655]	[7,142]	0	hSpCas9	negative selection	1823205
148836827	148836850	7	-	26627737	HCT116	viability after 6 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-1.4140466695484681	[390]	[24,21]	-7	hSpCas9	negative selection	1823206
148846469	148846492	7	-	26627737	HCT116	viability after 6 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.7266879646086334	[625]	[43,67]	-4	hSpCas9	negative selection	1823207
148847243	148847266	7	+	26627737	HCT116	viability after 6 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.3602826863761658	[707]	[116,69]	-2	hSpCas9	negative selection	1823208
148819603	148819626	7	+	26627737	HCT116	viability after 8 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-0.45421149636670877	[130]	[94,25,37]	-5	hSpCas9	negative selection	1905518
148827230	148827253	7	+	26627737	HCT116	viability after 8 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	1.1210792781397592	[90]	[159,49,117]	8	hSpCas9	negative selection	1905519
148828739	148828762	7	-	26627737	HCT116	viability after 8 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.3944397612340125	[165]	[30,100,75]	-5	hSpCas9	negative selection	1905520
148836827	148836850	7	-	26627737	HCT116	viability after 8 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.8068521182185172	[279]	[55,118,88]	-7	hSpCas9	negative selection	1905521
148846469	148846492	7	-	26627737	HCT116	viability after 8 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.7919008464167436	[448]	[145,159,122]	-7	hSpCas9	negative selection	1905522
148847243	148847266	7	+	26627737	HCT116	viability after 8 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.0035661346907081004	[711]	[443,419,311]	0	hSpCas9	negative selection	1905523
148819603	148819626	7	+	26627737	HCT116	viability after 9 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	1.5464546808746626	[385]	[185,391]	8	hSpCas9	negative selection	1987833
148827230	148827253	7	+	26627737	HCT116	viability after 9 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.8937722525490617	[747]	[35,163]	-6	hSpCas9	negative selection	1987834
148828739	148828762	7	-	26627737	HCT116	viability after 9 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.7595148233494347	[655]	[36,155]	-5	hSpCas9	negative selection	1987835
148836827	148836850	7	-	26627737	HCT116	viability after 9 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.44516841680279995	[390]	[31,111]	-3	hSpCas9	negative selection	1987836
148846469	148846492	7	-	26627737	HCT116	viability after 9 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.1071447860009176	[625]	[181,133]	0	hSpCas9	negative selection	1987837
148847243	148847266	7	+	26627737	HCT116	viability after 9 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.33852295268132343	[707]	[457,65]	2	hSpCas9	negative selection	1987838
148819603	148819626	7	+	26627737	HCT116	viability after 12 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.8853616281507369	[130]	[177,83,113]	7	hSpCas9	negative selection	2070148
148827230	148827253	7	+	26627737	HCT116	viability after 12 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	0.48522148369258167	[90]	[74,61,62]	5	hSpCas9	negative selection	2070149
148828739	148828762	7	-	26627737	HCT116	viability after 12 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.20809813977518354	[165]	[63,51,110]	-2	hSpCas9	negative selection	2070150
148836827	148836850	7	-	26627737	HCT116	viability after 12 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.7147321194603289	[279]	[101,93,71]	-6	hSpCas9	negative selection	2070151
148846469	148846492	7	-	26627737	HCT116	viability after 12 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.5424477405895307	[448]	[135,189,162]	-5	hSpCas9	negative selection	2070152
148847243	148847266	7	+	26627737	HCT116	viability after 12 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.030147856285820618	[711]	[386,472,287]	0	hSpCas9	negative selection	2070153
148819603	148819626	7	+	26627737	HCT116	viability after 15 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-0.03980412863565941	[130]	[21,90,99]	0	hSpCas9	negative selection	2152463
148827230	148827253	7	+	26627737	HCT116	viability after 15 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	0.6702016649458893	[90]	[58,58,127]	6	hSpCas9	negative selection	2152464
148828739	148828762	7	-	26627737	HCT116	viability after 15 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.9341472357216485	[165]	[28,56,60]	-7	hSpCas9	negative selection	2152465
148836827	148836850	7	-	26627737	HCT116	viability after 15 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.3268423393418375	[279]	[150,158,77]	-3	hSpCas9	negative selection	2152466
148846469	148846492	7	-	26627737	HCT116	viability after 15 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.6773564002358399	[448]	[123,177,176]	-6	hSpCas9	negative selection	2152467
148847243	148847266	7	+	26627737	HCT116	viability after 15 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.31435855190360606	[711]	[558,588,384]	3	hSpCas9	negative selection	2152468
148819603	148819626	7	+	26627737	HCT116	viability after 18 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-0.19784790350932568	[130]	[29,53,82]	-2	hSpCas9	negative selection	2234778
148827230	148827253	7	+	26627737	HCT116	viability after 18 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	0.21044152855605325	[90]	[43,16,95]	1	hSpCas9	negative selection	2234779
148828739	148828762	7	-	26627737	HCT116	viability after 18 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-1.4666352659354531	[165]	[18,16,52]	-8	hSpCas9	negative selection	2234780
148836827	148836850	7	-	26627737	HCT116	viability after 18 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.9030912791037263	[279]	[91,39,87]	-7	hSpCas9	negative selection	2234781
148846469	148846492	7	-	26627737	HCT116	viability after 18 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.8461705989228551	[448]	[98,28,245]	-7	hSpCas9	negative selection	2234782
148847243	148847266	7	+	26627737	HCT116	viability after 18 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.2020637347454941	[711]	[354,548,267]	1	hSpCas9	negative selection	2234783
148846484	148846507	7	+	24336569	HL60	viability	GCAATGAGCTCACAGAAGTCAGG	EZH2	ENSG00000106462	-0.560940464489289	[991]	[1422]	-5	hSpCas9	negative selection	2263698
148846495	148846518	7	+	24336569	HL60	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.36866144460795114	[866]	[1420]	-3	hSpCas9	negative selection	2263699
148846523	148846546	7	+	24336569	HL60	viability	TCCTTCGCTGTTTCCATTCTTGG	EZH2	ENSG00000106462	7.518448741558231	[0]	[387]	9	hSpCas9	negative selection	2263700
148846536	148846559	7	-	24336569	HL60	viability	CGGAAATCTTAAACCAAGAATGG	EZH2	ENSG00000106462	-0.8111063539892435	[261]	[315]	-6	hSpCas9	negative selection	2263701
148847181	148847204	7	-	24336569	HL60	viability	CAGACGAGCTGATGAAGTAAAGG	EZH2	ENSG00000106462	-0.8046595098951745	[642]	[778]	-6	hSpCas9	negative selection	2263702
148847206	148847229	7	-	24336569	HL60	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.5224968084406847	[559]	[824]	-5	hSpCas9	negative selection	2263703
148847243	148847266	7	+	24336569	HL60	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.22809543682804784	[327]	[812]	2	hSpCas9	negative selection	2263704
148847251	148847274	7	-	24336569	HL60	viability	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	1.0946131277950113	[363]	[1644]	8	hSpCas9	negative selection	2263705
148847267	148847290	7	-	24336569	HL60	viability	ACTGGGAAGAAATCTGAGAAGGG	EZH2	ENSG00000106462	-1.120242428385389	[640]	[623]	-7	hSpCas9	negative selection	2263706
148847284	148847307	7	-	24336569	HL60	viability	GAATAATCATGGGCCAGACTGGG	EZH2	ENSG00000106462	-0.7404858635219449	[1293]	[1638]	-6	hSpCas9	negative selection	2263707
148846484	148846507	7	+	24336569	KBM7	viability	GCAATGAGCTCACAGAAGTCAGG	EZH2	ENSG00000106462	-0.5663908102599851	[739]	[1362]	-4	hSpCas9	negative selection	2330875
148846495	148846518	7	+	24336569	KBM7	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-1.1352720196744173	[992]	[1232]	-7	hSpCas9	negative selection	2330876
148846523	148846546	7	+	24336569	KBM7	viability	TCCTTCGCTGTTTCCATTCTTGG	EZH2	ENSG00000106462	-1.7655492778675614	[90]	[72]	-8	hSpCas9	negative selection	2330877
148846536	148846559	7	-	24336569	KBM7	viability	CGGAAATCTTAAACCAAGAATGG	EZH2	ENSG00000106462	-0.2680681462773722	[199]	[452]	-2	hSpCas9	negative selection	2330878
148847181	148847204	7	-	24336569	KBM7	viability	CAGACGAGCTGATGAAGTAAAGG	EZH2	ENSG00000106462	-0.7558043395349178	[667]	[1078]	-5	hSpCas9	negative selection	2330879
148847206	148847229	7	-	24336569	KBM7	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.9683177421843554	[334]	[466]	-6	hSpCas9	negative selection	2330880
148847243	148847266	7	+	24336569	KBM7	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.06359013352926857	[363]	[949]	0	hSpCas9	negative selection	2330881
148847251	148847274	7	-	24336569	KBM7	viability	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	-1.1163732880735093	[495]	[623]	-7	hSpCas9	negative selection	2330882
148847267	148847290	7	-	24336569	KBM7	viability	ACTGGGAAGAAATCTGAGAAGGG	EZH2	ENSG00000106462	-1.4391176178006861	[339]	[341]	-7	hSpCas9	negative selection	2330883
148847284	148847307	7	-	24336569	KBM7	viability	GAATAATCATGGGCCAGACTGGG	EZH2	ENSG00000106462	-0.9585977376218653	[636]	[893]	-6	hSpCas9	negative selection	2330884
148824170	148824193	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCCGCCACCACGTCCAG	EZH2	ENSG00000106462	1.5618735705212097	[103,49]	[83,12]	6	dCas9-VP64	positive selection	2398345
148883676	148883699	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGACGGACTGTGTCTCCGGAGG	EZH2	ENSG00000106462	0.5466031240379366	[41,15]	[11,5]	2	dCas9-VP64	positive selection	2411396
148883577	148883600	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCCGGGGTGGGCAGGGCTCGG	EZH2	ENSG00000106462	0.898786765812916	[7,2]	[2,0]	3	dCas9-VP64	positive selection	2411397
148883655	148883678	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCTCGGCGCGAGGGGAAGGGG	EZH2	ENSG00000106462	3.5668721409012183	[26,7]	[72,16]	9	dCas9-VP64	positive selection	2411398
148884204	148884227	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGCGGCGGCGGCGCGCGGGGG	EZH2	ENSG00000106462	4.735450840763114	[17,20]	[44,195]	9	dCas9-VP64	positive selection	2457280
148824170	148824193	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCCGCCACCACGTCCAG	EZH2	ENSG00000106462	0.22222393386236713	[95,81]	[49,17]	1	dCas9-VP64	positive selection	2493600
148883676	148883699	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGACGGACTGTGTCTCCGGAGG	EZH2	ENSG00000106462	0.44867560372033566	[34,79]	[24,24]	3	dCas9-VP64	positive selection	2506651
148883577	148883600	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCCGGGGTGGGCAGGGCTCGG	EZH2	ENSG00000106462	-1.6866150649898723	[2,60]	[0,3]	-9	dCas9-VP64	positive selection	2506652
148883655	148883678	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCTCGGCGCGAGGGGAAGGGG	EZH2	ENSG00000106462	2.079302549241394	[90,38]	[114,66]	8	dCas9-VP64	positive selection	2506653
148884204	148884227	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGCGGCGGCGGCGCGCGGGGG	EZH2	ENSG00000106462	2.9792154948933054	[39,15]	[146,4]	9	dCas9-VP64	positive selection	2552535
148816710	148816733	7	+	27260157	DLD1	viability	AGGAGTATCCACATCCTCAGCGG	EZH2	ENSG00000106462	-0.240712893862416	[]	[]	-2	hSpCas9	negative selection	2574066
148818105	148818128	7	-	27260157	DLD1	viability	CATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	-0.805180224247973	[]	[]	-6	hSpCas9	negative selection	2575307
148827187	148827210	7	+	27260157	DLD1	viability	GCCCTTATCTGGAAACATTGAGG	EZH2	ENSG00000106462	-0.405579227434992	[]	[]	-3	hSpCas9	negative selection	2581755
148846473	148846496	7	-	27260157	DLD1	viability	TGAGCTCATTGCGCGGGACTAGG	EZH2	ENSG00000106462	-0.645937972194908	[]	[]	-5	hSpCas9	negative selection	2586082
148846495	148846518	7	+	27260157	DLD1	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.585418391136351	[]	[]	-5	hSpCas9	negative selection	2605994
148847206	148847229	7	-	27260157	DLD1	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.348904461178929	[]	[]	-3	hSpCas9	negative selection	2610117
148847243	148847266	7	+	27260157	DLD1	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.00240126127579709	[]	[]	0	hSpCas9	negative selection	2613351
148846523	148846546	7	+	27260157	DLD1	viability	TCCTTCGCTGTTTCCATTCTTGG	EZH2	ENSG00000106462	-0.293229547061664	[]	[]	-2	hSpCas9	negative selection	2616345
148846536	148846559	7	-	27260157	DLD1	viability	CGGAAATCTTAAACCAAGAATGG	EZH2	ENSG00000106462	0.652467364710045	[]	[]	8	hSpCas9	negative selection	2616938
148827244	148827267	7	-	27260157	DLD1	viability	ATAAAGAAAGCCGCCCACCTCGG	EZH2	ENSG00000106462	0.145749563193539	[]	[]	3	hSpCas9	negative selection	2616954
148818010	148818033	7	-	27260157	DLD1	viability	GGCTTCCCAATAACAGTAGCAGG	EZH2	ENSG00000106462	0.30401839828826	[]	[]	4	hSpCas9	negative selection	2619337
148846484	148846507	7	+	27260157	DLD1	viability	GCAATGAGCTCACAGAAGTCAGG	EZH2	ENSG00000106462	-0.378658228357868	[]	[]	-3	hSpCas9	negative selection	2620463
148828829	148828852	7	-	27260157	DLD1	viability	GTGGAGTTGGTGAATGCCCTTGG	EZH2	ENSG00000106462	-0.383637882329629	[]	[]	-3	hSpCas9	negative selection	2621708
148847267	148847290	7	-	27260157	DLD1	viability	ACTGGGAAGAAATCTGAGAAGGG	EZH2	ENSG00000106462	0.0361088468779249	[]	[]	0	hSpCas9	negative selection	2623294
148818024	148818047	7	+	27260157	DLD1	viability	TGGGAAGCCGTCCTCTTCTGCGG	EZH2	ENSG00000106462	0.190749854673915	[]	[]	3	hSpCas9	negative selection	2623885
148818076	148818099	7	-	27260157	DLD1	viability	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	0.5649229459261	[]	[]	8	hSpCas9	negative selection	2641280
148847251	148847274	7	-	27260157	DLD1	viability	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	-1.48205681808253	[]	[]	-8	hSpCas9	negative selection	2641455
148847181	148847204	7	-	27260157	DLD1	viability	CAGACGAGCTGATGAAGTAAAGG	EZH2	ENSG00000106462	-0.547990007764178	[]	[]	-4	hSpCas9	negative selection	2642449
148847284	148847307	7	-	27260157	DLD1	viability	GAATAATCATGGGCCAGACTGGG	EZH2	ENSG00000106462	-0.17876939566433	[]	[]	-1	hSpCas9	negative selection	2646138
148816710	148816733	7	+	27260157	HT1080	viability	AGGAGTATCCACATCCTCAGCGG	EZH2	ENSG00000106462	0.526701517205751	[]	[]	4	hSpCas9	negative selection	2650196
148818105	148818128	7	-	27260157	HT1080	viability	CATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	-0.465305887886328	[]	[]	-7	hSpCas9	negative selection	2651437
148827187	148827210	7	+	27260157	HT1080	viability	GCCCTTATCTGGAAACATTGAGG	EZH2	ENSG00000106462	0.261872101374771	[]	[]	2	hSpCas9	negative selection	2657885
148846473	148846496	7	-	27260157	HT1080	viability	TGAGCTCATTGCGCGGGACTAGG	EZH2	ENSG00000106462	-0.451143129664474	[]	[]	-7	hSpCas9	negative selection	2662212
148846495	148846518	7	+	27260157	HT1080	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	1.26927609764599	[]	[]	9	hSpCas9	negative selection	2682124
148847206	148847229	7	-	27260157	HT1080	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.915949389377573	[]	[]	7	hSpCas9	negative selection	2686247
148847243	148847266	7	+	27260157	HT1080	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.09477615063155	[]	[]	8	hSpCas9	negative selection	2689481
148846523	148846546	7	+	27260157	HT1080	viability	TCCTTCGCTGTTTCCATTCTTGG	EZH2	ENSG00000106462	0.892154810149105	[]	[]	7	hSpCas9	negative selection	2692475
148846536	148846559	7	-	27260157	HT1080	viability	CGGAAATCTTAAACCAAGAATGG	EZH2	ENSG00000106462	0.870325195839587	[]	[]	7	hSpCas9	negative selection	2693068
148827244	148827267	7	-	27260157	HT1080	viability	ATAAAGAAAGCCGCCCACCTCGG	EZH2	ENSG00000106462	1.14578052524936	[]	[]	8	hSpCas9	negative selection	2693084
148818010	148818033	7	-	27260157	HT1080	viability	GGCTTCCCAATAACAGTAGCAGG	EZH2	ENSG00000106462	-0.62491805458603	[]	[]	-8	hSpCas9	negative selection	2695467
148846484	148846507	7	+	27260157	HT1080	viability	GCAATGAGCTCACAGAAGTCAGG	EZH2	ENSG00000106462	1.86751867451667	[]	[]	9	hSpCas9	negative selection	2696593
148828829	148828852	7	-	27260157	HT1080	viability	GTGGAGTTGGTGAATGCCCTTGG	EZH2	ENSG00000106462	0.253975694180256	[]	[]	2	hSpCas9	negative selection	2697838
148847267	148847290	7	-	27260157	HT1080	viability	ACTGGGAAGAAATCTGAGAAGGG	EZH2	ENSG00000106462	2.207530933102	[]	[]	9	hSpCas9	negative selection	2699424
148818024	148818047	7	+	27260157	HT1080	viability	TGGGAAGCCGTCCTCTTCTGCGG	EZH2	ENSG00000106462	1.50899110784094	[]	[]	9	hSpCas9	negative selection	2700015
148818076	148818099	7	-	27260157	HT1080	viability	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	1.49515193478111	[]	[]	9	hSpCas9	negative selection	2717410
148847251	148847274	7	-	27260157	HT1080	viability	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	0.264048784559122	[]	[]	2	hSpCas9	negative selection	2717585
148847181	148847204	7	-	27260157	HT1080	viability	CAGACGAGCTGATGAAGTAAAGG	EZH2	ENSG00000106462	1.73005252069964	[]	[]	9	hSpCas9	negative selection	2718579
148847284	148847307	7	-	27260157	HT1080	viability	GAATAATCATGGGCCAGACTGGG	EZH2	ENSG00000106462	0.887228446944817	[]	[]	7	hSpCas9	negative selection	2722268
148816710	148816733	7	+	27260157	MKN45	viability	AGGAGTATCCACATCCTCAGCGG	EZH2	ENSG00000106462	0.147340971770904	[]	[]	5	hSpCas9	negative selection	2726326
148818105	148818128	7	-	27260157	MKN45	viability	CATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.59250154555192	[]	[]	7	hSpCas9	negative selection	2727567
148827187	148827210	7	+	27260157	MKN45	viability	GCCCTTATCTGGAAACATTGAGG	EZH2	ENSG00000106462	-0.33678381372598	[]	[]	-1	hSpCas9	negative selection	2734015
148846473	148846496	7	-	27260157	MKN45	viability	TGAGCTCATTGCGCGGGACTAGG	EZH2	ENSG00000106462	0.716053722459312	[]	[]	7	hSpCas9	negative selection	2738342
148846495	148846518	7	+	27260157	MKN45	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	0.986110154105287	[]	[]	8	hSpCas9	negative selection	2758254
148847206	148847229	7	-	27260157	MKN45	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.496921982851195	[]	[]	6	hSpCas9	negative selection	2762377
148847243	148847266	7	+	27260157	MKN45	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.42712203303684	[]	[]	9	hSpCas9	negative selection	2765611
148846523	148846546	7	+	27260157	MKN45	viability	TCCTTCGCTGTTTCCATTCTTGG	EZH2	ENSG00000106462	0.159268449631259	[]	[]	5	hSpCas9	negative selection	2768605
148846536	148846559	7	-	27260157	MKN45	viability	CGGAAATCTTAAACCAAGAATGG	EZH2	ENSG00000106462	1.54484139363707	[]	[]	9	hSpCas9	negative selection	2769198
148827244	148827267	7	-	27260157	MKN45	viability	ATAAAGAAAGCCGCCCACCTCGG	EZH2	ENSG00000106462	0.392805531595453	[]	[]	6	hSpCas9	negative selection	2769214
148818010	148818033	7	-	27260157	MKN45	viability	GGCTTCCCAATAACAGTAGCAGG	EZH2	ENSG00000106462	-0.218546192040893	[]	[]	-1	hSpCas9	negative selection	2771597
148846484	148846507	7	+	27260157	MKN45	viability	GCAATGAGCTCACAGAAGTCAGG	EZH2	ENSG00000106462	1.19901918898559	[]	[]	9	hSpCas9	negative selection	2772723
148828829	148828852	7	-	27260157	MKN45	viability	GTGGAGTTGGTGAATGCCCTTGG	EZH2	ENSG00000106462	0.653140660361116	[]	[]	7	hSpCas9	negative selection	2773968
148847267	148847290	7	-	27260157	MKN45	viability	ACTGGGAAGAAATCTGAGAAGGG	EZH2	ENSG00000106462	0.623876457405394	[]	[]	7	hSpCas9	negative selection	2775554
148818024	148818047	7	+	27260157	MKN45	viability	TGGGAAGCCGTCCTCTTCTGCGG	EZH2	ENSG00000106462	0.571936116920521	[]	[]	7	hSpCas9	negative selection	2776145
148818076	148818099	7	-	27260157	MKN45	viability	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	1.38203657888453	[]	[]	9	hSpCas9	negative selection	2793540
148847251	148847274	7	-	27260157	MKN45	viability	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	-0.0915515743596354	[]	[]	0	hSpCas9	negative selection	2793715
148847181	148847204	7	-	27260157	MKN45	viability	CAGACGAGCTGATGAAGTAAAGG	EZH2	ENSG00000106462	1.69143949569503	[]	[]	9	hSpCas9	negative selection	2794709
148847284	148847307	7	-	27260157	MKN45	viability	GAATAATCATGGGCCAGACTGGG	EZH2	ENSG00000106462	0.554731486689701	[]	[]	7	hSpCas9	negative selection	2798398
148816710	148816733	7	+	27260157	RKO	viability	AGGAGTATCCACATCCTCAGCGG	EZH2	ENSG00000106462	0.0566353407830161	[]	[]	0	hSpCas9	negative selection	2802456
148818105	148818128	7	-	27260157	RKO	viability	CATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.45443806236558	[]	[]	2	hSpCas9	negative selection	2803697
148827187	148827210	7	+	27260157	RKO	viability	GCCCTTATCTGGAAACATTGAGG	EZH2	ENSG00000106462	0.116458287885657	[]	[]	0	hSpCas9	negative selection	2810145
148846473	148846496	7	-	27260157	RKO	viability	TGAGCTCATTGCGCGGGACTAGG	EZH2	ENSG00000106462	0.0117045501999027	[]	[]	0	hSpCas9	negative selection	2814472
148846495	148846518	7	+	27260157	RKO	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	0.0185528081915461	[]	[]	0	hSpCas9	negative selection	2834384
148847206	148847229	7	-	27260157	RKO	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.260537624845336	[]	[]	1	hSpCas9	negative selection	2838507
148847243	148847266	7	+	27260157	RKO	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.188394735899241	[]	[]	1	hSpCas9	negative selection	2841741
148846523	148846546	7	+	27260157	RKO	viability	TCCTTCGCTGTTTCCATTCTTGG	EZH2	ENSG00000106462	0.0465287933089416	[]	[]	0	hSpCas9	negative selection	2844735
148846536	148846559	7	-	27260157	RKO	viability	CGGAAATCTTAAACCAAGAATGG	EZH2	ENSG00000106462	0.723792543399917	[]	[]	8	hSpCas9	negative selection	2845328
148827244	148827267	7	-	27260157	RKO	viability	ATAAAGAAAGCCGCCCACCTCGG	EZH2	ENSG00000106462	0.32526508718017	[]	[]	1	hSpCas9	negative selection	2845344
148818010	148818033	7	-	27260157	RKO	viability	GGCTTCCCAATAACAGTAGCAGG	EZH2	ENSG00000106462	0.478675949604578	[]	[]	2	hSpCas9	negative selection	2847727
148846484	148846507	7	+	27260157	RKO	viability	GCAATGAGCTCACAGAAGTCAGG	EZH2	ENSG00000106462	0.721900090981559	[]	[]	8	hSpCas9	negative selection	2848853
148828829	148828852	7	-	27260157	RKO	viability	GTGGAGTTGGTGAATGCCCTTGG	EZH2	ENSG00000106462	0.214082874993443	[]	[]	1	hSpCas9	negative selection	2850098
148847267	148847290	7	-	27260157	RKO	viability	ACTGGGAAGAAATCTGAGAAGGG	EZH2	ENSG00000106462	1.07096915381206	[]	[]	9	hSpCas9	negative selection	2851684
148818024	148818047	7	+	27260157	RKO	viability	TGGGAAGCCGTCCTCTTCTGCGG	EZH2	ENSG00000106462	-0.422042864653055	[]	[]	-6	hSpCas9	negative selection	2852275
148818076	148818099	7	-	27260157	RKO	viability	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	1.00461930946218	[]	[]	9	hSpCas9	negative selection	2869670
148847251	148847274	7	-	27260157	RKO	viability	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	0.12262180579231	[]	[]	0	hSpCas9	negative selection	2869845
148847181	148847204	7	-	27260157	RKO	viability	CAGACGAGCTGATGAAGTAAAGG	EZH2	ENSG00000106462	0.123101590046195	[]	[]	0	hSpCas9	negative selection	2870839
148847284	148847307	7	-	27260157	RKO	viability	GAATAATCATGGGCCAGACTGGG	EZH2	ENSG00000106462	-0.580457099219129	[]	[]	-7	hSpCas9	negative selection	2874528
148816710	148816733	7	+	27260157	SF268	viability	AGGAGTATCCACATCCTCAGCGG	EZH2	ENSG00000106462	1.01526223306488	[]	[]	9	hSpCas9	negative selection	2878586
148818105	148818128	7	-	27260157	SF268	viability	CATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.265125781123147	[]	[]	4	hSpCas9	negative selection	2879827
148827187	148827210	7	+	27260157	SF268	viability	GCCCTTATCTGGAAACATTGAGG	EZH2	ENSG00000106462	0.77822076233948	[]	[]	8	hSpCas9	negative selection	2886275
148846473	148846496	7	-	27260157	SF268	viability	TGAGCTCATTGCGCGGGACTAGG	EZH2	ENSG00000106462	-0.364912506462614	[]	[]	-3	hSpCas9	negative selection	2890602
148846495	148846518	7	+	27260157	SF268	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	1.22057497528256	[]	[]	9	hSpCas9	negative selection	2910514
148847206	148847229	7	-	27260157	SF268	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.0688420176727861	[]	[]	0	hSpCas9	negative selection	2914637
148847243	148847266	7	+	27260157	SF268	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.293624261384671	[]	[]	4	hSpCas9	negative selection	2917871
148846523	148846546	7	+	27260157	SF268	viability	TCCTTCGCTGTTTCCATTCTTGG	EZH2	ENSG00000106462	1.26372194245943	[]	[]	9	hSpCas9	negative selection	2920865
148846536	148846559	7	-	27260157	SF268	viability	CGGAAATCTTAAACCAAGAATGG	EZH2	ENSG00000106462	1.41956628449933	[]	[]	9	hSpCas9	negative selection	2921458
148827244	148827267	7	-	27260157	SF268	viability	ATAAAGAAAGCCGCCCACCTCGG	EZH2	ENSG00000106462	0.743146272358189	[]	[]	8	hSpCas9	negative selection	2921474
148818010	148818033	7	-	27260157	SF268	viability	GGCTTCCCAATAACAGTAGCAGG	EZH2	ENSG00000106462	0.450683837610184	[]	[]	7	hSpCas9	negative selection	2923857
148846484	148846507	7	+	27260157	SF268	viability	GCAATGAGCTCACAGAAGTCAGG	EZH2	ENSG00000106462	1.83334165139182	[]	[]	9	hSpCas9	negative selection	2924983
148828829	148828852	7	-	27260157	SF268	viability	GTGGAGTTGGTGAATGCCCTTGG	EZH2	ENSG00000106462	0.996113315213651	[]	[]	9	hSpCas9	negative selection	2926228
148847267	148847290	7	-	27260157	SF268	viability	ACTGGGAAGAAATCTGAGAAGGG	EZH2	ENSG00000106462	2.21586137564023	[]	[]	9	hSpCas9	negative selection	2927814
148818024	148818047	7	+	27260157	SF268	viability	TGGGAAGCCGTCCTCTTCTGCGG	EZH2	ENSG00000106462	1.00327378454283	[]	[]	9	hSpCas9	negative selection	2928405
148818076	148818099	7	-	27260157	SF268	viability	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	1.29235875134325	[]	[]	9	hSpCas9	negative selection	2945800
148847251	148847274	7	-	27260157	SF268	viability	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	0.249662428677993	[]	[]	4	hSpCas9	negative selection	2945975
148847181	148847204	7	-	27260157	SF268	viability	CAGACGAGCTGATGAAGTAAAGG	EZH2	ENSG00000106462	0.941770746394194	[]	[]	9	hSpCas9	negative selection	2946969
148847284	148847307	7	-	27260157	SF268	viability	GAATAATCATGGGCCAGACTGGG	EZH2	ENSG00000106462	0.467673857866426	[]	[]	7	hSpCas9	negative selection	2950658
148847251	148847274	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	-0.410501627795897	[3,3]	[1,2]	-5	hSpCas9	positive selection	2986746
148818076	148818099	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	-0.0433868145115799	[3,4]	[3,3]	0	hSpCas9	positive selection	2986747
148827228	148827251	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATCAGAAGGAAATTTCCGAGG	EZH2	ENSG00000106462	-0.3009241341925134	[4,4]	[5,0]	-4	hSpCas9	positive selection	2986748
148829734	148829757	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATGATGGGAAAGTACACGGGG	EZH2	ENSG00000106462	-0.6483723678351149	[3,3]	[2,0]	-7	hSpCas9	positive selection	2986749
148847251	148847274	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	-0.49676710514838524	[3,3]	[2,0]	-7	hSpCas9	positive selection	3054604
148818076	148818099	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	0.28710019615411075	[3,3]	[3,2]	5	hSpCas9	positive selection	3054605
148827228	148827251	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATCAGAAGGAAATTTCCGAGG	EZH2	ENSG00000106462	-0.18587307993681668	[4,4]	[5,1]	-3	hSpCas9	positive selection	3054606
148829734	148829757	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATGATGGGAAAGTACACGGGG	EZH2	ENSG00000106462	-0.18878193293932555	[3,3]	[2,1]	-3	hSpCas9	positive selection	3054607
148847243	148847266		+	24336571	A375	resistance to PLX after 7 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.02930621770617181	[22,23]	[23,21]	-1	hSpCas9	positive selection	3112907
148829784	148829807		-	24336571	A375	resistance to PLX after 7 days	GATGAAGTTTTAGATCAGGATGG	EZH2	ENSG00000106462	0.13920713609461371	[9,6]	[8,9]	4	hSpCas9	positive selection	3112908
148847206	148847229		-	24336571	A375	resistance to PLX after 7 days	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.2348402943578074	[37,36]	[46,40]	7	hSpCas9	positive selection	3112909
148829809	148829832		-	24336571	A375	resistance to PLX after 7 days	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	-0.04900209773186881	[39,32]	[35,34]	-1	hSpCas9	positive selection	3112910
148847243	148847266		+	24336571	A375	resistance to PLX after 14 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.5487578259710126	[20,18]	[13,13]	5	hSpCas9	positive selection	3170700
148829784	148829807		-	24336571	A375	resistance to PLX after 14 days	GATGAAGTTTTAGATCAGGATGG	EZH2	ENSG00000106462	0.9969217506988665	[8,6]	[7,6]	7	hSpCas9	positive selection	3170701
148847206	148847229		-	24336571	A375	resistance to PLX after 14 days	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.6998134091294534	[33,32]	[25,24]	6	hSpCas9	positive selection	3170702
148829809	148829832		-	24336571	A375	resistance to PLX after 14 days	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	-0.0707854817393565	[40,34]	[13,19]	0	hSpCas9	positive selection	3170703
148847243	148847266		+	24336571	A375	viability after 7 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.8485364406585513	[44]	[22,23]	-8	hSpCas9	negative selection	3228493
148829784	148829807		-	24336571	A375	viability after 7 days	GATGAAGTTTTAGATCAGGATGG	EZH2	ENSG00000106462	-0.591609389753662	[13]	[9,6]	-7	hSpCas9	negative selection	3228494
148847206	148847229		-	24336571	A375	viability after 7 days	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.140657701635148	[43]	[37,36]	-2	hSpCas9	negative selection	3228495
148829809	148829832		-	24336571	A375	viability after 7 days	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	-0.9808386545215286	[76]	[39,32]	-9	hSpCas9	negative selection	3228496
148847243	148847266		+	24336571	A375	viability after 14 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-1.0442647780574992	[44]	[20,18]	-8	hSpCas9	negative selection	3286286
148829784	148829807		-	24336571	A375	viability after 14 days	GATGAAGTTTTAGATCAGGATGG	EZH2	ENSG00000106462	-0.6333347555946636	[13]	[8,6]	-6	hSpCas9	negative selection	3286287
148847206	148847229		-	24336571	A375	viability after 14 days	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.2821218958865854	[43]	[33,32]	-3	hSpCas9	negative selection	3286288
148829809	148829832		-	24336571	A375	viability after 14 days	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	-0.9057502850710455	[76]	[40,34]	-8	hSpCas9	negative selection	3286289
148847243	148847266	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.672461936770054	[94,96]	[0,0]	3	hSpCas9	positive selection	3348639
148847206	148847229	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.09771865764407096	[138,146]	[0,0]	0	hSpCas9	positive selection	3348640
148829796	148829819	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	2.3013060132801493	[36,24]	[0,0]	8	hSpCas9	positive selection	3348641
148828812	148828835	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-1.3125293968851128	[379,379]	[0,0]	-8	hSpCas9	positive selection	3367844
148829809	148829832	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	-2.204153235840321	[704,704]	[0,0]	-9	hSpCas9	positive selection	3367845
148828755	148828778	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	1.2129320920873818	[65,65]	[0,0]	5	hSpCas9	positive selection	3367846
148847251	148847274	7	-	26780180	HT29	viability (Avana library 4 designs)	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	1.49269165708606	[]	[]	6	hSpCas9	negative selection	3423581
148818076	148818099	7	-	26780180	HT29	viability (Avana library 4 designs)	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	-0.476918554302533	[]	[]	-7	hSpCas9	negative selection	3423582
148827227	148827250	7	+	26780180	HT29	viability (Avana library 4 designs)	TTATCAGAAGGAAATTTCCGAGG	EZH2	ENSG00000106462	0.991531130229956	[]	[]	4	hSpCas9	negative selection	3423583
148829734	148829757	7	-	26780180	HT29	viability (Avana library 4 designs)	TTATGATGGGAAAGTACACGGGG	EZH2	ENSG00000106462	0.747463953100555	[]	[]	3	hSpCas9	negative selection	3423584
148827227	148827250	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATCAGAAGGAAATTTCCGAGG	EZH2	ENSG00000106462	-7.44754539273968	[]	[]	-6	hSpCas9	negative selection	3504805
148829734	148829757	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTATGATGGGAAAGTACACGGGG	EZH2	ENSG00000106462	-2.47725319904535	[]	[]	-3	hSpCas9	negative selection	3504806
148847251	148847274	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	3.74712899209899	[]	[]	6	hSpCas9	negative selection	3504807
148818076	148818099	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	5.73183946784572	[]	[]	9	hSpCas9	negative selection	3504808
148819656	148819679	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-3.90714433048508	[]	[]	-4	hSpCas9	negative selection	3504809
148828752	148828775	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-5.31802778475519	[]	[]	-5	hSpCas9	negative selection	3504810
148827227	148827250	7	+	26780180	A375	viability (Avana lentiGuide)	TTATCAGAAGGAAATTTCCGAGG	EZH2	ENSG00000106462	7.96492148918611	[]	[]	6	hSpCas9	negative selection	3613464
148829734	148829757	7	-	26780180	A375	viability (Avana lentiGuide)	TTATGATGGGAAAGTACACGGGG	EZH2	ENSG00000106462	8.85670409014663	[]	[]	6	hSpCas9	negative selection	3613465
148847251	148847274	7	-	26780180	A375	viability (Avana lentiGuide)	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	5.74817608774299	[]	[]	5	hSpCas9	negative selection	3613466
148818076	148818099	7	-	26780180	A375	viability (Avana lentiGuide)	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	3.48307730030033	[]	[]	3	hSpCas9	negative selection	3613467
148819656	148819679	7	-	26780180	A375	viability (Avana lentiGuide)	CAACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	10.5306792803513	[]	[]	7	hSpCas9	negative selection	3613468
148828752	148828775	7	-	26780180	A375	viability (Avana lentiGuide)	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	3.39800637070375	[]	[]	3	hSpCas9	negative selection	3613469
148827227	148827250	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATCAGAAGGAAATTTCCGAGG	EZH2	ENSG00000106462	-0.24737169785138513	[7]	[6,5]	-4	hSpCas9	positive selection	3722123
148829734	148829757	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATGATGGGAAAGTACACGGGG	EZH2	ENSG00000106462	0.18474673234468433	[5]	[6,6]	5	hSpCas9	positive selection	3722124
148847251	148847274	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	0.31837228154081226	[5]	[7,6]	8	hSpCas9	positive selection	3722125
148818076	148818099	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	0.3432063010548132	[5]	[6,6]	8	hSpCas9	positive selection	3722126
148819656	148819679	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-0.029828069478242597	[5]	[5,5]	0	hSpCas9	positive selection	3722127
148828752	148828775	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.15249188102723166	[7]	[6,6]	-2	hSpCas9	positive selection	3722128
148827227	148827250	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATCAGAAGGAAATTTCCGAGG	EZH2	ENSG00000106462	0.20389137365712307	[6]	[6,6]	5	hSpCas9	positive selection	3830730
148829734	148829757	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATGATGGGAAAGTACACGGGG	EZH2	ENSG00000106462	0.06230497720949423	[5]	[4,4]	1	hSpCas9	positive selection	3830731
148847251	148847274	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGGGACCAGTTTGTTGGCGG	EZH2	ENSG00000106462	0.15221757007285666	[5]	[5,5]	3	hSpCas9	positive selection	3830732
148818076	148818099	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCTGCTCTCACCGCTGAGCGG	EZH2	ENSG00000106462	0.271111321140983	[5]	[5,5]	7	hSpCas9	positive selection	3830733
148819656	148819679	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	0.3874446271547802	[6]	[6,7]	9	hSpCas9	positive selection	3830734
148828752	148828775	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	0.18063051381065492	[7]	[6,6]	4	hSpCas9	positive selection	3830735
148829796	148829819	7	+	26780180	A375	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.467176232938938	[]	[]	1	hSpCas9	negative selection	3938096
148847243	148847266	7	+	26780180	A375	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.966377372341158	[]	[]	4	hSpCas9	negative selection	3938097
148828755	148828778	7	-	26780180	A375	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	1.88122075956195	[]	[]	9	hSpCas9	negative selection	3938098
148828812	148828835	7	+	26780180	A375	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.574617331834957	[]	[]	1	hSpCas9	negative selection	3938099
148847206	148847229	7	-	26780180	A375	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	1.64776964398006	[]	[]	8	hSpCas9	negative selection	3938100
148829809	148829832	7	-	26780180	A375	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	-0.212053483176124	[]	[]	-6	hSpCas9	negative selection	3938101
148829796	148829819	7	+	26780180	HT29	viability (GeCKOv2 library)	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.588772090875916	[]	[]	2	hSpCas9	negative selection	4046062
148847243	148847266	7	+	26780180	HT29	viability (GeCKOv2 library)	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.521150042765898	[]	[]	1	hSpCas9	negative selection	4046063
148828755	148828778	7	-	26780180	HT29	viability (GeCKOv2 library)	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	1.74568613815782	[]	[]	8	hSpCas9	negative selection	4046064
148828812	148828835	7	+	26780180	HT29	viability (GeCKOv2 library)	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.241517446798615	[]	[]	0	hSpCas9	negative selection	4046065
148847206	148847229	7	-	26780180	HT29	viability (GeCKOv2 library)	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	2.14673578930191	[]	[]	9	hSpCas9	negative selection	4046066
148829809	148829832	7	-	26780180	HT29	viability (GeCKOv2 library)	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	-0.485798046609868	[]	[]	-9	hSpCas9	negative selection	4046067
148847243	148847266	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.24700281217534498	[4]	[3,3]	6	hSpCas9	positive selection	4135663
148829784	148829807	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGAAGTTTTAGATCAGGATGG	EZH2	ENSG00000106462	0.3822777521957689	[3]	[3,2]	8	hSpCas9	positive selection	4135664
148847206	148847229	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.36109177818231275	[5]	[5,4]	8	hSpCas9	positive selection	4135665
148829809	148829832	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.24533926049929483	[4]	[3,3]	6	hSpCas9	positive selection	4135666
148847243	148847266	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.826527522771613	[6]	[5,5,5,3]	5	hSpCas9	positive selection	4199685
148829784	148829807	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGAAGTTTTAGATCAGGATGG	EZH2	ENSG00000106462	1.1164658174939281	[3]	[3,1,4,2]	8	hSpCas9	positive selection	4199686
148847206	148847229	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	1.242419743811823	[5]	[5,3,4,5]	8	hSpCas9	positive selection	4199687
148829809	148829832	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	1.047159307389736	[6]	[6,5,5,5]	7	hSpCas9	positive selection	4199688
148847243	148847266	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.34763803329823795	[2]	[3,2]	7	hSpCas9	positive selection	4269524
148847206	148847229	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.47521044649580035	[3]	[2,0]	-8	hSpCas9	positive selection	4269525
148829796	148829819	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.418170930144105	[1]	[2,0]	8	hSpCas9	positive selection	4269526
148828812	148828835	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.3460091039715916	[3]	[4,3]	7	hSpCas9	positive selection	4333789
148829809	148829832	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.6667205080089165	[4]	[5,5]	9	hSpCas9	positive selection	4333790
148828755	148828778	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.5145309121036046	[3]	[2,0]	-8	hSpCas9	positive selection	4333791
148818065	148818087	7	+	27760321	OCIAML3	viability	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	-0.5139189168435429	[520,433]	[259,260]	-5	hSpCas9	negative selection	4398839
148818105	148818127	7	-	27760321	OCIAML3	viability	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.23352025951118222	[359,324]	[252,394]	2	hSpCas9	negative selection	4398840
148819584	148819606	7	+	27760321	OCIAML3	viability	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	-0.8911828788008147	[256,181]	[35,163]	-7	hSpCas9	negative selection	4398841
148819656	148819678	7	-	27760321	OCIAML3	viability	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-4.118180139537154	[26,17]	[0,0]	-9	hSpCas9	negative selection	4398842
148826571	148826593	7	+	27760321	OCIAML3	viability	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.14633574844673186	[455,373]	[247,348]	-1	hSpCas9	negative selection	4398843
148818065	148818087	7	+	27760321	OCIAML2	viability	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.3011402406197542	[520,433]	[460,490]	4	hSpCas9	negative selection	4482302
148818105	148818127	7	-	27760321	OCIAML2	viability	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.5324555351184428	[359,324]	[364,446]	7	hSpCas9	negative selection	4482303
148819584	148819606	7	+	27760321	OCIAML2	viability	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	-0.08583023233157605	[256,181]	[152,181]	-1	hSpCas9	negative selection	4482304
148819656	148819678	7	-	27760321	OCIAML2	viability	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-2.1594619856170834	[26,17]	[0,7]	-9	hSpCas9	negative selection	4482305
148826571	148826593	7	+	27760321	OCIAML2	viability	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.42759809565026335	[455,373]	[168,352]	-5	hSpCas9	negative selection	4482306
148818065	148818087	7	+	27760321	MV411	viability	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.6671891391270867	[520,433]	[590,358]	5	hSpCas9	negative selection	4565765
148818105	148818127	7	-	27760321	MV411	viability	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.5790490277958864	[359,324]	[493,101]	4	hSpCas9	negative selection	4565766
148819584	148819606	7	+	27760321	MV411	viability	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.3988397003965908	[256,181]	[96,326]	3	hSpCas9	negative selection	4565767
148819656	148819678	7	-	27760321	MV411	viability	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-3.873101570622472	[26,17]	[0,0]	-9	hSpCas9	negative selection	4565768
148826571	148826593	7	+	27760321	MV411	viability	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	0.05905798740860055	[455,373]	[193,418]	0	hSpCas9	negative selection	4565769
148818065	148818087	7	+	27760321	HL60	viability	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.8779654623626766	[520,433]	[724,701]	8	hSpCas9	negative selection	4649228
148818105	148818127	7	-	27760321	HL60	viability	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.2410381794548641	[359,324]	[308,352]	3	hSpCas9	negative selection	4649229
148819584	148819606	7	+	27760321	HL60	viability	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	-0.5636489621629714	[256,181]	[136,101]	-6	hSpCas9	negative selection	4649230
148819656	148819678	7	-	27760321	HL60	viability	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	0.7125773259527484	[26,17]	[3,56]	7	hSpCas9	negative selection	4649231
148826571	148826593	7	+	27760321	HL60	viability	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.10500192893703406	[455,373]	[236,394]	-1	hSpCas9	negative selection	4649232
148818065	148818087	7	+	27760321	HT1080	viability	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	3.5867393972717503	[433,338]	[2450,1191]	9	hSpCas9	negative selection	4732691
148818105	148818127	7	-	27760321	HT1080	viability	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	1.8107364474801506	[324,253]	[438,366]	8	hSpCas9	negative selection	4732692
148819584	148819606	7	+	27760321	HT1080	viability	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	1.8533671882313585	[181,141]	[310,147]	8	hSpCas9	negative selection	4732693
148819656	148819678	7	-	27760321	HT1080	viability	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	2.397137121782062	[17,13]	[34,31]	9	hSpCas9	negative selection	4732694
148826571	148826593	7	+	27760321	HT1080	viability	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-1.2206453941774171	[373,291]	[107,0]	-5	hSpCas9	negative selection	4732695
148818065	148818087	7	+	27760321	HT29	viability after 7 days	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	-0.002036074530336121	[433,338]	[438,643,399]	0	hSpCas9	negative selection	4816154
148818105	148818127	7	-	27760321	HT29	viability after 7 days	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.17206157175180345	[324,253]	[436,368,452]	2	hSpCas9	negative selection	4816155
148819584	148819606	7	+	27760321	HT29	viability after 7 days	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.2628330356333505	[181,141]	[367,205,193]	4	hSpCas9	negative selection	4816156
148819656	148819678	7	-	27760321	HT29	viability after 7 days	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	0.6397384270159394	[17,13]	[46,43,7]	8	hSpCas9	negative selection	4816157
148826571	148826593	7	+	27760321	HT29	viability after 7 days	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	0.39678873786196517	[373,291]	[550,463,669]	6	hSpCas9	negative selection	4816158
148818065	148818087	7	+	27760321	HT29	viability after 25 days	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.6898116395523876	[433,338]	[695,595,860]	7	hSpCas9	negative selection	4899617
148818105	148818127	7	-	27760321	HT29	viability after 25 days	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.21900281510421138	[324,253]	[277,295,610]	2	hSpCas9	negative selection	4899618
148819584	148819606	7	+	27760321	HT29	viability after 25 days	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.29821757477367583	[181,141]	[57,297,349]	3	hSpCas9	negative selection	4899619
148819656	148819678	7	-	27760321	HT29	viability after 25 days	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	0.4779854144580238	[17,13]	[0,15,64]	5	hSpCas9	negative selection	4899620
148826571	148826593	7	+	27760321	HT29	viability after 25 days	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.5060087291228152	[373,291]	[53,253,536]	-5	hSpCas9	negative selection	4899621
148818065	148818087	7	+	27760321	HT29	viability after 22 days	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.5462358370833763	[433,338]	[595,501,862]	6	hSpCas9	negative selection	4983080
148818105	148818127	7	-	27760321	HT29	viability after 22 days	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	-0.018787497290777833	[324,253]	[169,436,388]	0	hSpCas9	negative selection	4983081
148819584	148819606	7	+	27760321	HT29	viability after 22 days	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.16148503866451291	[181,141]	[93,273,263]	1	hSpCas9	negative selection	4983082
148819656	148819678	7	-	27760321	HT29	viability after 22 days	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-1.2859322089132643	[17,13]	[0,6,14]	-7	hSpCas9	negative selection	4983083
148826571	148826593	7	+	27760321	HT29	viability after 22 days	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.5395382250262476	[373,291]	[44,229,527]	-5	hSpCas9	negative selection	4983084
148818065	148818087	7	+	27760321	HT29	viability after 19 days	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.2980414588287421	[433,338]	[711,398,536]	3	hSpCas9	negative selection	5066543
148818105	148818127	7	-	27760321	HT29	viability after 19 days	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.010202976148496856	[324,253]	[615,300,120]	0	hSpCas9	negative selection	5066544
148819584	148819606	7	+	27760321	HT29	viability after 19 days	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.35677418648985715	[181,141]	[102,181,405]	3	hSpCas9	negative selection	5066545
148819656	148819678	7	-	27760321	HT29	viability after 19 days	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-0.11783356289623725	[17,13]	[1,2,42]	-1	hSpCas9	negative selection	5066546
148826571	148826593	7	+	27760321	HT29	viability after 19 days	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.4480468840327067	[373,291]	[145,440,237]	-4	hSpCas9	negative selection	5066547
148818065	148818087	7	+	27760321	HT29	viability after 16 days	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.3571447991829198	[433,338]	[679,344,653]	4	hSpCas9	negative selection	5150006
148818105	148818127	7	-	27760321	HT29	viability after 16 days	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.5423058151629714	[324,253]	[472,441,500]	6	hSpCas9	negative selection	5150007
148819584	148819606	7	+	27760321	HT29	viability after 16 days	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	-0.17865457932602213	[181,141]	[135,201,138]	-2	hSpCas9	negative selection	5150008
148819656	148819678	7	-	27760321	HT29	viability after 16 days	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-0.3853539213723316	[17,13]	[0,9,28]	-4	hSpCas9	negative selection	5150009
148826571	148826593	7	+	27760321	HT29	viability after 16 days	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.1803850648526138	[373,291]	[338,261,387]	-2	hSpCas9	negative selection	5150010
148818065	148818087	7	+	27760321	HT29	viability after 13 days	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.4834577665595299	[433,338]	[851,467,563]	6	hSpCas9	negative selection	5233469
148818105	148818127	7	-	27760321	HT29	viability after 13 days	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	0.15607866607254048	[324,253]	[325,493,306]	2	hSpCas9	negative selection	5233470
148819584	148819606	7	+	27760321	HT29	viability after 13 days	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.0351229374110551	[181,141]	[198,123,250]	0	hSpCas9	negative selection	5233471
148819656	148819678	7	-	27760321	HT29	viability after 13 days	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	0.47355171207045377	[17,13]	[12,49,14]	6	hSpCas9	negative selection	5233472
148826571	148826593	7	+	27760321	HT29	viability after 13 days	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-0.30492705401644726	[373,291]	[199,299,430]	-4	hSpCas9	negative selection	5233473
148818065	148818087	7	+	27760321	HT29	viability after 10 days	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	0.6449566757011557	[433,338]	[964,865,442]	8	hSpCas9	negative selection	5316932
148818105	148818127	7	-	27760321	HT29	viability after 10 days	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	-0.020219891657554778	[324,253]	[276,485,310]	0	hSpCas9	negative selection	5316933
148819584	148819606	7	+	27760321	HT29	viability after 10 days	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.4453249722669621	[181,141]	[317,252,254]	6	hSpCas9	negative selection	5316934
148819656	148819678	7	-	27760321	HT29	viability after 10 days	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-1.2641370799611158	[17,13]	[6,9,7]	-8	hSpCas9	negative selection	5316935
148826571	148826593	7	+	27760321	HT29	viability after 10 days	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	0.27321419858992996	[373,291]	[405,418,675]	3	hSpCas9	negative selection	5316936
148818065	148818087	7	+	27760321	MOLM13	viability	GGGGTCTTTATCCGCTCAGCGG	EZH2	ENSG00000106462	-1.0828936903852955	[520,433]	[238,30]	-6	hSpCas9	negative selection	5400395
148818105	148818127	7	-	27760321	MOLM13	viability	ATTTCGTAGGAGGGAGCAAAGG	EZH2	ENSG00000106462	-0.302670085993492	[359,324]	[209,110]	-2	hSpCas9	negative selection	5400396
148819584	148819606	7	+	27760321	MOLM13	viability	ACTAAGTCTTACCAAATGCTGG	EZH2	ENSG00000106462	0.19247814617079373	[256,181]	[287,13]	1	hSpCas9	negative selection	5400397
148819656	148819678	7	-	27760321	MOLM13	viability	AACACCCAACACTTATAAGCGG	EZH2	ENSG00000106462	-3.647044757794877	[26,17]	[0,0]	-9	hSpCas9	negative selection	5400398
148826571	148826593	7	+	27760321	MOLM13	viability	TGTTGGGGGTACATTCAGGAGG	EZH2	ENSG00000106462	-2.8494820357115045	[455,373]	[0,58]	-8	hSpCas9	negative selection	5400399
148883769	148883792	7	+	27661255	K562	viability	GCCGCGGCCGCGCCACACAAAGG	EZH2	ENSG00000106462	0.6399890724012884	[316,528]	[571,478]	9	dCas9-KRAB	negative selection	5478219
148883861	148883884	7	+	27661255	K562	viability	GCCAGGACAAGCACCGGGAAAGG	EZH2	ENSG00000106462	-0.08534842581198654	[560,624]	[504,394]	-3	dCas9-KRAB	negative selection	5478220
148884253	148884276	7	-	27661255	K562	viability	GGTCGCGTCCGACACCCGGTGGG	EZH2	ENSG00000106462	0.261971095091605	[1066,1147]	[1215,925]	8	dCas9-KRAB	negative selection	5478221
148884257	148884280	7	-	27661255	K562	viability	GTCCGGTCGCGTCCGACACCCGG	EZH2	ENSG00000106462	0.24758584299648767	[686,729]	[695,649]	8	dCas9-KRAB	negative selection	5478222
148847243	148847266	7	+	27260156	BXPC3	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.3830915375824027	[430]	[464,664,591,639]	7	hSpCas9	negative selection	5541984
148847206	148847229	7	-	27260156	BXPC3	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.005259578766949269	[686]	[655,569,744,952]	0	hSpCas9	negative selection	5541985
148829796	148829819	7	+	27260156	BXPC3	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.21721239338250653	[87]	[82,92,125,131]	5	hSpCas9	negative selection	5541986
148828812	148828835	7	+	27260156	BXPC3	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.10248219652230861	[857]	[932,898,1063,957]	2	hSpCas9	negative selection	5606249
148829809	148829832	7	-	27260156	BXPC3	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.2553882897665307	[1072]	[1219,1349,1365,1435]	5	hSpCas9	negative selection	5606250
148828755	148828778	7	-	27260156	BXPC3	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.8302412032259918	[481]	[247,217,412,259]	-9	hSpCas9	negative selection	5606251
148847243	148847266	7	+	27260156	A673	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.6098092353248276	[430]	[833,734,831,760]	9	hSpCas9	negative selection	5663235
148847206	148847229	7	-	27260156	A673	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.15429975967024379	[686]	[843,907,936,975]	3	hSpCas9	negative selection	5663236
148829796	148829819	7	+	27260156	A673	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	-0.11855256157272498	[87]	[114,66,65,146]	-3	hSpCas9	negative selection	5663237
148828812	148828835	7	+	27260156	A673	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.19872809356163834	[857]	[1418,1047,1059,1234]	5	hSpCas9	negative selection	5727500
148829809	148829832	7	-	27260156	A673	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.25028428976246087	[1072]	[1674,1490,1432,1546]	6	hSpCas9	negative selection	5727501
148828755	148828778	7	-	27260156	A673	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.8890036978130623	[481]	[361,337,331,216]	-9	hSpCas9	negative selection	5727502
148847243	148847266	7	+	27260156	A375	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.5280967542992299	[430]	[622,716,861,699]	7	hSpCas9	negative selection	5784486
148847206	148847229	7	-	27260156	A375	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.44555884739509233	[686]	[658,661,628,433]	-6	hSpCas9	negative selection	5784487
148829796	148829819	7	+	27260156	A375	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.7550538987521804	[87]	[150,196,245,109]	9	hSpCas9	negative selection	5784488
148828812	148828835	7	+	27260156	A375	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.027515051045859273	[857]	[1118,885,1049,1009]	0	hSpCas9	negative selection	5848751
148829809	148829832	7	-	27260156	A375	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.7008557950050256	[1072]	[1938,2493,1877,1907]	9	hSpCas9	negative selection	5848752
148828755	148828778	7	-	27260156	A375	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.6918866894259199	[481]	[411,228,289,434]	-7	hSpCas9	negative selection	5848753
148847243	148847266	7	+	27260156	COLO741	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.48580989709666283	[430]	[888,848,596]	8	hSpCas9	negative selection	5905737
148847206	148847229	7	-	27260156	COLO741	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.014218799406795823	[686]	[766,1000,831]	0	hSpCas9	negative selection	5905738
148829796	148829819	7	+	27260156	COLO741	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.49178689649926044	[87]	[151,128,189]	8	hSpCas9	negative selection	5905739
148828812	148828835	7	+	27260156	COLO741	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.2643487801329517	[857]	[1202,1754,1003]	5	hSpCas9	negative selection	5970002
148829809	148829832	7	-	27260156	COLO741	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.3867361450200246	[1072]	[1775,1914,1688]	7	hSpCas9	negative selection	5970003
148828755	148828778	7	-	27260156	COLO741	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.2172097370389514	[481]	[304,249,243]	-9	hSpCas9	negative selection	5970004
148847243	148847266	7	+	27260156	CAL120	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.18479506126519624	[430]	[704,641,497]	2	hSpCas9	negative selection	6026988
148847206	148847229	7	-	27260156	CAL120	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.32947642990829606	[686]	[751,700,599]	-5	hSpCas9	negative selection	6026989
148829796	148829819	7	+	27260156	CAL120	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.578586048561649	[87]	[421,31,76]	8	hSpCas9	negative selection	6026990
148828812	148828835	7	+	27260156	CAL120	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.23714845583398392	[857]	[1418,844,1529]	3	hSpCas9	negative selection	6091253
148829809	148829832	7	-	27260156	CAL120	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.680825871534072	[1072]	[2060,2402,1947]	8	hSpCas9	negative selection	6091254
148828755	148828778	7	-	27260156	CAL120	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.5036077255626314	[481]	[167,306,153]	-9	hSpCas9	negative selection	6091255
148847243	148847266	7	+	27260156	CADOES1	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.39492946848056987	[430]	[305,307,311,292]	-6	hSpCas9	negative selection	6148239
148847206	148847229	7	-	27260156	CADOES1	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.1918260888519761	[686]	[518,603,600,511]	-3	hSpCas9	negative selection	6148240
148829796	148829819	7	+	27260156	CADOES1	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.008947518673113386	[87]	[158,41,74,51]	0	hSpCas9	negative selection	6148241
148828812	148828835	7	+	27260156	CADOES1	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.14439188759309707	[857]	[1009,972,786,752]	2	hSpCas9	negative selection	6212504
148829809	148829832	7	-	27260156	CADOES1	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.6427226680430334	[1072]	[1396,1457,1575,1810]	9	hSpCas9	negative selection	6212505
148828755	148828778	7	-	27260156	CADOES1	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.8120170634778362	[481]	[193,218,388,217]	-8	hSpCas9	negative selection	6212506
148847243	148847266	7	+	27260156	EWS502	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.702578128880675	[430]	[783,663,880,631]	9	hSpCas9	negative selection	6269490
148847206	148847229	7	-	27260156	EWS502	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.21932934253924397	[686]	[651,678,694,454]	-4	hSpCas9	negative selection	6269491
148829796	148829819	7	+	27260156	EWS502	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	1.0164605844125527	[87]	[175,262,220,84]	9	hSpCas9	negative selection	6269492
148828812	148828835	7	+	27260156	EWS502	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.023152100497120243	[857]	[923,842,1094,826]	0	hSpCas9	negative selection	6333755
148829809	148829832	7	-	27260156	EWS502	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5169086698452148	[1072]	[1354,1430,1947,1823]	8	hSpCas9	negative selection	6333756
148828755	148828778	7	-	27260156	EWS502	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.276730495687088	[481]	[221,182,193,244]	-9	hSpCas9	negative selection	6333757
148847243	148847266	7	+	27260156	EW8	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.06484352826481475	[430]	[375,353,361,242]	-1	hSpCas9	negative selection	6390741
148847206	148847229	7	-	27260156	EW8	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.04200917483959099	[686]	[551,449,607,671]	0	hSpCas9	negative selection	6390742
148829796	148829819	7	+	27260156	EW8	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.4932829002170669	[87]	[101,77,131,83]	8	hSpCas9	negative selection	6390743
148828812	148828835	7	+	27260156	EW8	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-0.03759010797335238	[857]	[661,634,651,760]	0	hSpCas9	negative selection	6455006
148829809	148829832	7	-	27260156	EW8	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5035495558088621	[1072]	[1518,1380,1010,1086]	8	hSpCas9	negative selection	6455007
148828755	148828778	7	-	27260156	EW8	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.5412640078865685	[481]	[172,129,78,167]	-9	hSpCas9	negative selection	6455008
148847243	148847266	7	+	27260156	CORL105	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.5272088768455709	[430]	[825,619,915,581]	8	hSpCas9	negative selection	6511992
148847206	148847229	7	-	27260156	CORL105	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.034059655478081874	[686]	[696,805,1035,783]	0	hSpCas9	negative selection	6511993
148829796	148829819	7	+	27260156	CORL105	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.2041869494409818	[87]	[115,89,180,97]	4	hSpCas9	negative selection	6511994
148828812	148828835	7	+	27260156	CORL105	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.15985014031457057	[857]	[972,1084,1390,1076]	3	hSpCas9	negative selection	6576257
148829809	148829832	7	-	27260156	CORL105	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.4295301339207662	[1072]	[1625,1533,1901,1737]	7	hSpCas9	negative selection	6576258
148828755	148828778	7	-	27260156	CORL105	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.0091969420523272	[481]	[269,306,214,317]	-9	hSpCas9	negative selection	6576259
148847243	148847266	7	+	27260156	HS294T	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.5776114467745178	[430]	[212,320,231,224]	7	hSpCas9	negative selection	6633243
148847206	148847229	7	-	27260156	HS294T	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.1437971321853858	[686]	[495,207,228,208]	2	hSpCas9	negative selection	6633244
148829796	148829819	7	+	27260156	HS294T	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.10780269714914192	[87]	[16,65,29,33]	1	hSpCas9	negative selection	6633245
148828812	148828835	7	+	27260156	HS294T	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.2544058487375541	[857]	[505,337,336,390]	3	hSpCas9	negative selection	6697508
148829809	148829832	7	-	27260156	HS294T	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.41991002628492735	[1072]	[454,623,414,766]	5	hSpCas9	negative selection	6697509
148828755	148828778	7	-	27260156	HS294T	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.7367348699863527	[481]	[50,64,49,57]	-9	hSpCas9	negative selection	6697510
148847243	148847266	7	+	27260156	HCC44	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.6061559318996429	[430]	[795,373,924,948]	8	hSpCas9	negative selection	6754494
148847206	148847229	7	-	27260156	HCC44	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.16109297202948558	[686]	[854,473,941,594]	-3	hSpCas9	negative selection	6754495
148829796	148829819	7	+	27260156	HCC44	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.19057471786516222	[87]	[131,131,84,98]	3	hSpCas9	negative selection	6754496
148828812	148828835	7	+	27260156	HCC44	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.14271599104574462	[857]	[1105,947,1332,958]	2	hSpCas9	negative selection	6818759
148829809	148829832	7	-	27260156	HCC44	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5395070443228072	[1072]	[1965,1400,2043,1748]	8	hSpCas9	negative selection	6818760
148828755	148828778	7	-	27260156	HCC44	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.4250933292192145	[481]	[186,201,159,250]	-9	hSpCas9	negative selection	6818761
148847243	148847266	7	+	27260156	G402	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.7226192416758238	[430]	[649,848,444,1461]	8	hSpCas9	negative selection	6875745
148847206	148847229	7	-	27260156	G402	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.12624430713897822	[686]	[716,980,582,791]	-1	hSpCas9	negative selection	6875746
148829796	148829819	7	+	27260156	G402	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.19383824007332517	[87]	[193,131,166,13]	2	hSpCas9	negative selection	6875747
148828812	148828835	7	+	27260156	G402	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-0.5018972202218299	[857]	[833,711,585,829]	-6	hSpCas9	negative selection	6940010
148829809	148829832	7	-	27260156	G402	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.793534272010098	[1072]	[3167,2072,2119,1846]	8	hSpCas9	negative selection	6940011
148828755	148828778	7	-	27260156	G402	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.2584934350198411	[481]	[349,185,255,203]	-8	hSpCas9	negative selection	6940012
148847243	148847266	7	+	27260156	L33	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.34048866006854434	[430]	[527,215,372,534]	7	hSpCas9	negative selection	6996996
148847206	148847229	7	-	27260156	L33	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.24068790194702233	[686]	[735,234,313,512]	-5	hSpCas9	negative selection	6996997
148829796	148829819	7	+	27260156	L33	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.03054530403259781	[87]	[133,22,52,83]	0	hSpCas9	negative selection	6996998
148828812	148828835	7	+	27260156	L33	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.11260269954410329	[857]	[978,384,504,985]	2	hSpCas9	negative selection	7061261
148829809	148829832	7	-	27260156	L33	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.15380236448327378	[1072]	[1203,549,667,1164]	3	hSpCas9	negative selection	7061262
148828755	148828778	7	-	27260156	L33	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.9068237433551053	[481]	[191,93,159,352]	-9	hSpCas9	negative selection	7061263
148847243	148847266	7	+	27260156	K562	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.6829268606113689	[430]	[774,686,549,474]	8	hSpCas9	negative selection	7118247
148847206	148847229	7	-	27260156	K562	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.2199093063678041	[686]	[707,470,495,438]	-3	hSpCas9	negative selection	7118248
148829796	148829819	7	+	27260156	K562	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.5192017846809391	[87]	[94,161,46,140]	6	hSpCas9	negative selection	7118249
148828812	148828835	7	+	27260156	K562	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.8360433683369167	[857]	[877,821,1044,2484]	9	hSpCas9	negative selection	7182512
148829809	148829832	7	-	27260156	K562	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.473807017262168	[1072]	[1509,1699,794,1314]	6	hSpCas9	negative selection	7182513
148828755	148828778	7	-	27260156	K562	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.0478683458473417	[481]	[180,323,64,254]	-8	hSpCas9	negative selection	7182514
148847243	148847266	7	+	27260156	HT29	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.43878194487337213	[430]	[717,616,844,654]	8	hSpCas9	negative selection	7239498
148847206	148847229	7	-	27260156	HT29	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.0011849994192267843	[686]	[1119,877,684,696]	0	hSpCas9	negative selection	7239499
148829796	148829819	7	+	27260156	HT29	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.3616315610638976	[87]	[113,216,104,119]	7	hSpCas9	negative selection	7239500
148828812	148828835	7	+	27260156	HT29	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.27026197926474504	[857]	[1363,1362,1112,1205]	5	hSpCas9	negative selection	7303763
148829809	148829832	7	-	27260156	HT29	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.40728204701134785	[1072]	[1840,1782,1729,1583]	7	hSpCas9	negative selection	7303764
148828755	148828778	7	-	27260156	HT29	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.0956561372706815	[481]	[256,379,312,165]	-9	hSpCas9	negative selection	7303765
148847243	148847266	7	+	27260156	MHHES1	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.07550626293358931	[430]	[587,663,443,390]	1	hSpCas9	negative selection	7360749
148847206	148847229	7	-	27260156	MHHES1	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.30261192768373113	[686]	[477,640,743,617]	-5	hSpCas9	negative selection	7360750
148829796	148829819	7	+	27260156	MHHES1	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.2489480158411408	[87]	[180,184,73,56]	4	hSpCas9	negative selection	7360751
148828812	148828835	7	+	27260156	MHHES1	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.2609456697548228	[857]	[1572,1200,1071,878]	5	hSpCas9	negative selection	7425014
148829809	148829832	7	-	27260156	MHHES1	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5535184603780001	[1072]	[1861,2353,1642,1360]	8	hSpCas9	negative selection	7425015
148828755	148828778	7	-	27260156	MHHES1	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.7910977045955466	[481]	[380,234,369,271]	-9	hSpCas9	negative selection	7425016
148847243	148847266	7	+	27260156	MEWO	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.27126951055031523	[430]	[390,545,503]	6	hSpCas9	negative selection	7482000
148847206	148847229	7	-	27260156	MEWO	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.2615905698941736	[686]	[865,738,724]	5	hSpCas9	negative selection	7482001
148829796	148829819	7	+	27260156	MEWO	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	-0.2131168519137736	[87]	[60,93,55]	-5	hSpCas9	negative selection	7482002
148828812	148828835	7	+	27260156	MEWO	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-0.004887003703500259	[857]	[986,603,845]	0	hSpCas9	negative selection	7546265
148829809	148829832	7	-	27260156	MEWO	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.3793168358059449	[1072]	[1512,1324,1118]	7	hSpCas9	negative selection	7546266
148828755	148828778	7	-	27260156	MEWO	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.9553097121366506	[481]	[215,320,156]	-9	hSpCas9	negative selection	7546267
148847243	148847266	7	+	27260156	LNCAPCLONEFGC	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.040866195108620065	[430]	[280,391,460,396]	0	hSpCas9	negative selection	7603251
148847206	148847229	7	-	27260156	LNCAPCLONEFGC	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.34879845846164886	[686]	[424,407,596,546]	-5	hSpCas9	negative selection	7603252
148829796	148829819	7	+	27260156	LNCAPCLONEFGC	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.48010529882727293	[87]	[89,113,131,111]	7	hSpCas9	negative selection	7603253
148828812	148828835	7	+	27260156	LNCAPCLONEFGC	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-0.04223520683005966	[857]	[816,607,948,681]	0	hSpCas9	negative selection	7667516
148829809	148829832	7	-	27260156	LNCAPCLONEFGC	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5663629231005993	[1072]	[1414,1374,1432,1536]	8	hSpCas9	negative selection	7667517
148828755	148828778	7	-	27260156	LNCAPCLONEFGC	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.4333105967543538	[481]	[253,116,122,147]	-9	hSpCas9	negative selection	7667518
148847243	148847266	7	+	27260156	PANC0327	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.6533569564774926	[430]	[680,475,511,761]	8	hSpCas9	negative selection	7724502
148847206	148847229	7	-	27260156	PANC0327	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.7327375865084805	[686]	[1866,609,776,923]	9	hSpCas9	negative selection	7724503
148829796	148829819	7	+	27260156	PANC0327	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.22826714988629737	[87]	[114,131,88,26]	3	hSpCas9	negative selection	7724504
148828812	148828835	7	+	27260156	PANC0327	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.23201344370272092	[857]	[849,970,958,786]	3	hSpCas9	negative selection	7788767
148829809	148829832	7	-	27260156	PANC0327	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.6281474291575309	[1072]	[1374,1260,1312,1961]	8	hSpCas9	negative selection	7788768
148828755	148828778	7	-	27260156	PANC0327	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.8400665442440338	[481]	[477,59,80,379]	-8	hSpCas9	negative selection	7788769
148847243	148847266	7	+	27260156	NCIH2009	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.024251223363601734	[430]	[621,553,605]	0	hSpCas9	negative selection	7845753
148847206	148847229	7	-	27260156	NCIH2009	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.019988291268772995	[686]	[1099,925,842]	0	hSpCas9	negative selection	7845754
148829796	148829819	7	+	27260156	NCIH2009	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.1681712502094017	[87]	[64,234,97]	2	hSpCas9	negative selection	7845755
148828812	148828835	7	+	27260156	NCIH2009	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.038644601593548655	[857]	[1597,1192,973]	0	hSpCas9	negative selection	7910018
148829809	148829832	7	-	27260156	NCIH2009	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.603518622598703	[1072]	[2549,1970,2367]	8	hSpCas9	negative selection	7910019
148828755	148828778	7	-	27260156	NCIH2009	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.5847957517598469	[481]	[395,656,278]	-6	hSpCas9	negative selection	7910020
148847243	148847266	7	+	27260156	NCIH1373	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.24738557317544305	[430]	[591,485,613,160]	2	hSpCas9	negative selection	7967004
148847206	148847229	7	-	27260156	NCIH1373	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.49933774290558997	[686]	[725,542,208,195]	-5	hSpCas9	negative selection	7967005
148829796	148829819	7	+	27260156	NCIH1373	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	-0.6991704789619928	[87]	[70,84,28,14]	-6	hSpCas9	negative selection	7967006
148828812	148828835	7	+	27260156	NCIH1373	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.3878360340514565	[857]	[967,812,1602,436]	4	hSpCas9	negative selection	8031269
148829809	148829832	7	-	27260156	NCIH1373	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	1.1730196639001405	[1072]	[2883,2226,2530,869]	9	hSpCas9	negative selection	8031270
148828755	148828778	7	-	27260156	NCIH1373	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.2029310186616402	[481]	[337,171,109,91]	-8	hSpCas9	negative selection	8031271
148847243	148847266	7	+	27260156	PATU8902	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.2867634732248734	[430]	[766,902,454,888]	3	hSpCas9	negative selection	8088255
148847206	148847229	7	-	27260156	PATU8902	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.1084560074942994	[686]	[875,946,909,792]	-1	hSpCas9	negative selection	8088256
148829796	148829819	7	+	27260156	PATU8902	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.39317951205243196	[87]	[271,65,151,151]	4	hSpCas9	negative selection	8088257
148828812	148828835	7	+	27260156	PATU8902	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.39854293442886835	[857]	[1593,956,1732,2012]	4	hSpCas9	negative selection	8152520
148829809	148829832	7	-	27260156	PATU8902	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	1.2029963243214843	[1072]	[3587,2923,3631,3548]	9	hSpCas9	negative selection	8152521
148828755	148828778	7	-	27260156	PATU8902	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.489531995689778	[481]	[318,973,258,408]	-5	hSpCas9	negative selection	8152522
148847243	148847266	7	+	27260156	PANC1	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.014663719209575724	[430]	[319,528,275,367]	0	hSpCas9	negative selection	8209506
148847206	148847229	7	-	27260156	PANC1	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.053394815412258045	[686]	[526,668,672,439]	-1	hSpCas9	negative selection	8209507
148829796	148829819	7	+	27260156	PANC1	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.7634998699938642	[87]	[152,80,59,194]	9	hSpCas9	negative selection	8209508
148828812	148828835	7	+	27260156	PANC1	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.08300389836566946	[857]	[688,850,911,689]	1	hSpCas9	negative selection	8273771
148829809	148829832	7	-	27260156	PANC1	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5539343071369809	[1072]	[1468,1741,1415,913]	8	hSpCas9	negative selection	8273772
148828755	148828778	7	-	27260156	PANC1	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.106180452200482	[481]	[112,306,170,198]	-8	hSpCas9	negative selection	8273773
148847243	148847266	7	+	27260156	PANC0813	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.252102395406384	[430]	[645,577,661,532]	4	hSpCas9	negative selection	8330757
148847206	148847229	7	-	27260156	PANC0813	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.19410729186337589	[686]	[810,460,715,834]	-3	hSpCas9	negative selection	8330758
148829796	148829819	7	+	27260156	PANC0813	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	-0.40330875661769783	[87]	[47,63,120,76]	-6	hSpCas9	negative selection	8330759
148828812	148828835	7	+	27260156	PANC0813	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.18731415395732387	[857]	[1137,1418,1103,937]	3	hSpCas9	negative selection	8395022
148829809	148829832	7	-	27260156	PANC0813	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.20198462507769155	[1072]	[1732,1551,1100,1435]	3	hSpCas9	negative selection	8395023
148828755	148828778	7	-	27260156	PANC0813	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.2075299025714805	[481]	[208,237,231,294]	-9	hSpCas9	negative selection	8395024
148847243	148847266	7	+	27260156	RDES	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.33300137200582675	[430]	[554,546,617,807]	5	hSpCas9	negative selection	8452008
148847206	148847229	7	-	27260156	RDES	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.10593630906727897	[686]	[578,677,960,745]	-2	hSpCas9	negative selection	8452009
148829796	148829819	7	+	27260156	RDES	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.41967531359696353	[87]	[115,146,144,131]	6	hSpCas9	negative selection	8452010
148828812	148828835	7	+	27260156	RDES	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.2028936276280383	[857]	[965,1050,1231,1337]	3	hSpCas9	negative selection	8516273
148829809	148829832	7	-	27260156	RDES	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.6436290877370376	[1072]	[1535,1670,2027,2641]	9	hSpCas9	negative selection	8516274
148828755	148828778	7	-	27260156	RDES	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.0966498633688881	[481]	[187,278,251,334]	-9	hSpCas9	negative selection	8516275
148847243	148847266	7	+	27260156	PC3	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.43727645542017296	[430]	[383,762,686,546]	8	hSpCas9	negative selection	8573259
148847206	148847229	7	-	27260156	PC3	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.15711098255496037	[686]	[319,794,1267,1018]	3	hSpCas9	negative selection	8573260
148829796	148829819	7	+	27260156	PC3	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.3913700635943793	[87]	[80,124,202,85]	7	hSpCas9	negative selection	8573261
148828812	148828835	7	+	27260156	PC3	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.11397277254127836	[857]	[410,920,1554,1232]	2	hSpCas9	negative selection	8637524
148829809	148829832	7	-	27260156	PC3	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.30856801753972407	[1072]	[944,1388,1823,1351]	6	hSpCas9	negative selection	8637525
148828755	148828778	7	-	27260156	PC3	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.9519231663284461	[481]	[112,316,425,242]	-9	hSpCas9	negative selection	8637526
148847243	148847266	7	+	27260156	PATU8988T	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.7059608145264149	[430]	[808,757,514,641]	9	hSpCas9	negative selection	8694510
148847206	148847229	7	-	27260156	PATU8988T	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.37256782009013045	[686]	[824,878,721,1028]	6	hSpCas9	negative selection	8694511
148829796	148829819	7	+	27260156	PATU8988T	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	-0.2942568609164611	[87]	[136,57,42,35]	-5	hSpCas9	negative selection	8694512
148828812	148828835	7	+	27260156	PATU8988T	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.142920794712191	[857]	[955,1114,669,944]	2	hSpCas9	negative selection	8758775
148829809	148829832	7	-	27260156	PATU8988T	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5122701713067517	[1072]	[1426,1598,1051,1886]	8	hSpCas9	negative selection	8758776
148828755	148828778	7	-	27260156	PATU8988T	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.1779979200533683	[481]	[169,234,155,270]	-9	hSpCas9	negative selection	8758777
148847243	148847266	7	+	27260156	T47D	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.378740798837666	[430]	[618,521,778,701]	7	hSpCas9	negative selection	8815761
148847206	148847229	7	-	27260156	T47D	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	0.09275274800759692	[686]	[857,885,782,885]	2	hSpCas9	negative selection	8815762
148829796	148829819	7	+	27260156	T47D	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.5091792793508749	[87]	[116,141,163,160]	9	hSpCas9	negative selection	8815763
148828812	148828835	7	+	27260156	T47D	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.02487603065521038	[857]	[978,987,1017,1086]	0	hSpCas9	negative selection	8880026
148829809	148829832	7	-	27260156	T47D	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.44848035170925593	[1072]	[1782,1598,1593,1862]	8	hSpCas9	negative selection	8880027
148828755	148828778	7	-	27260156	T47D	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.8999336797127506	[481]	[224,342,312,318]	-9	hSpCas9	negative selection	8880028
148847243	148847266	7	+	27260156	SU8686	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.5103113842543232	[430]	[648,529,634,624]	8	hSpCas9	negative selection	8937012
148847206	148847229	7	-	27260156	SU8686	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.0009090138296758976	[686]	[644,665,708,708]	0	hSpCas9	negative selection	8937013
148829796	148829819	7	+	27260156	SU8686	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.5273571240799046	[87]	[83,85,203,142]	8	hSpCas9	negative selection	8937014
148828812	148828835	7	+	27260156	SU8686	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.3182435674572971	[857]	[849,938,967,1602]	5	hSpCas9	negative selection	9001277
148829809	148829832	7	-	27260156	SU8686	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5401439107174331	[1072]	[1332,1335,1728,1890]	8	hSpCas9	negative selection	9001278
148828755	148828778	7	-	27260156	SU8686	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.5471379311084602	[481]	[338,269,284,433]	-7	hSpCas9	negative selection	9001279
148847243	148847266	7	+	27260156	SKES1	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.3872555610204124	[430]	[446,638,523,619]	7	hSpCas9	negative selection	9058263
148847206	148847229	7	-	27260156	SKES1	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.27058864542476796	[686]	[491,741,600,454]	-5	hSpCas9	negative selection	9058264
148829796	148829819	7	+	27260156	SKES1	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.42481586272838556	[87]	[122,111,167,71]	8	hSpCas9	negative selection	9058265
148828812	148828835	7	+	27260156	SKES1	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	0.0610594234917764	[857]	[884,895,914,867]	1	hSpCas9	negative selection	9122528
148829809	148829832	7	-	27260156	SKES1	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.337762648915787	[1072]	[1757,1470,1264,1014]	7	hSpCas9	negative selection	9122529
148828755	148828778	7	-	27260156	SKES1	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.4625735299518163	[481]	[178,243,140,144]	-9	hSpCas9	negative selection	9122530
148847243	148847266	7	+	27260156	TOV112D	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.23315141039827939	[430]	[675,684,413,316]	4	hSpCas9	negative selection	9179514
148847206	148847229	7	-	27260156	TOV112D	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.5414393146867356	[686]	[429,476,518,461]	-8	hSpCas9	negative selection	9179515
148829796	148829819	7	+	27260156	TOV112D	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.04306898381741853	[87]	[103,162,61,53]	0	hSpCas9	negative selection	9179516
148828812	148828835	7	+	27260156	TOV112D	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-0.12129268395030013	[857]	[957,909,634,701]	-2	hSpCas9	negative selection	9243779
148829809	148829832	7	-	27260156	TOV112D	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.15228039961227635	[1072]	[1374,1443,1023,1013]	3	hSpCas9	negative selection	9243780
148828755	148828778	7	-	27260156	TOV112D	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.4541770646526961	[481]	[137,165,155,236]	-9	hSpCas9	negative selection	9243781
148847243	148847266	7	+	27260156	TC71	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.3172632321765473	[430]	[619,522,525,637]	7	hSpCas9	negative selection	9300765
148847206	148847229	7	-	27260156	TC71	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.22506519083059429	[686]	[689,619,544,668]	-6	hSpCas9	negative selection	9300766
148829796	148829819	7	+	27260156	TC71	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	-0.0600478462594598	[87]	[141,62,51,105]	-1	hSpCas9	negative selection	9300767
148828812	148828835	7	+	27260156	TC71	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-0.01746584118715766	[857]	[937,891,868,937]	0	hSpCas9	negative selection	9365030
148829809	148829832	7	-	27260156	TC71	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.3633692215803048	[1072]	[1480,1512,1251,1692]	8	hSpCas9	negative selection	9365031
148828755	148828778	7	-	27260156	TC71	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-0.8725656883004396	[481]	[230,345,223,333]	-9	hSpCas9	negative selection	9365032
148847243	148847266	7	+	27260156	TC32	viability	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	-0.2969232671513894	[430]	[391,174,411,388]	-5	hSpCas9	negative selection	9422016
148847206	148847229	7	-	27260156	TC32	viability	TGCGACTGAGACAGCTCAAGAGG	EZH2	ENSG00000106462	-0.0843253654253397	[686]	[452,565,560,859]	-1	hSpCas9	negative selection	9422017
148829796	148829819	7	+	27260156	TC32	viability	AAAACTTCATCTCCCATATAAGG	EZH2	ENSG00000106462	0.266671486430063	[87]	[199,35,92,70]	5	hSpCas9	negative selection	9422018
148828812	148828835	7	+	27260156	TC32	viability	CATCATCATTATATTGACCAAGG	EZH2	ENSG00000106462	-0.04630832184142997	[857]	[675,651,1064,794]	-1	hSpCas9	negative selection	9486281
148829809	148829832	7	-	27260156	TC32	viability	TTTACATAACATTCCTTATATGG	EZH2	ENSG00000106462	0.5699481331502982	[1072]	[1374,1114,1923,1731]	8	hSpCas9	negative selection	9486282
148828755	148828778	7	-	27260156	TC32	viability	AGAAGAAAAGCAGAAAGATCTGG	EZH2	ENSG00000106462	-1.3481525683743047	[481]	[226,98,159,238]	-9	hSpCas9	negative selection	9486283
148819603	148819626	7	+	27869803	HPAFII	viability after 27 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-0.07687231163092734	[117]	[48,66,NaN]	0	hSpCas9	negative selection	9598527
148827230	148827253	7	+	27869803	HPAFII	viability after 27 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-1.9650034581000422	[186]	[4,41,NaN]	-8	hSpCas9	negative selection	9598528
148828739	148828762	7	-	27869803	HPAFII	viability after 27 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.512850202331538	[131]	[70,29,NaN]	-4	hSpCas9	negative selection	9598529
148836827	148836850	7	-	27869803	HPAFII	viability after 27 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	-0.022698267216088364	[139]	[102,46,NaN]	0	hSpCas9	negative selection	9598530
148846469	148846492	7	-	27869803	HPAFII	viability after 27 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.8912891819840666	[171]	[284,69,NaN]	7	hSpCas9	negative selection	9598531
148847243	148847266	7	+	27869803	HPAFII	viability after 27 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.0716805233183675	[430]	[418,523,NaN]	8	hSpCas9	negative selection	9598532
148819603	148819626	7	+	27869803	HPAFII	viability after 15 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.6479949187904397	[117]	[260,159,NaN]	7	hSpCas9	negative selection	9680976
148827230	148827253	7	+	27869803	HPAFII	viability after 15 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-1.4210648029295825	[186]	[87,66,NaN]	-8	hSpCas9	negative selection	9680977
148828739	148828762	7	-	27869803	HPAFII	viability after 15 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.2940396353451944	[131]	[185,71,NaN]	-3	hSpCas9	negative selection	9680978
148836827	148836850	7	-	27869803	HPAFII	viability after 15 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	1.19507327598411	[139]	[444,281,NaN]	9	hSpCas9	negative selection	9680979
148846469	148846492	7	-	27869803	HPAFII	viability after 15 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.592566095801064	[171]	[406,198,NaN]	6	hSpCas9	negative selection	9680980
148847243	148847266	7	+	27869803	HPAFII	viability after 15 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.6949123404478996	[430]	[948,625,NaN]	7	hSpCas9	negative selection	9680981
148819603	148819626	7	+	27869803	ASPC1	viability after 36 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	1.0040003518016227	[274]	[289,300,35]	8	hSpCas9	negative selection	9763425
148827230	148827253	7	+	27869803	ASPC1	viability after 36 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.3969284070894913	[501]	[194,145,77]	-4	hSpCas9	negative selection	9763426
148828739	148828762	7	-	27869803	ASPC1	viability after 36 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.4994991732479386	[236]	[122,172,66]	5	hSpCas9	negative selection	9763427
148836827	148836850	7	-	27869803	ASPC1	viability after 36 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	2.5348134322649467	[344]	[690,1297,218]	9	hSpCas9	negative selection	9763428
148846469	148846492	7	-	27869803	ASPC1	viability after 36 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.03415801788365544	[701]	[561,90,156]	0	hSpCas9	negative selection	9763429
148847243	148847266	7	+	27869803	ASPC1	viability after 36 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.40835259726740913	[1339]	[805,624,480]	4	hSpCas9	negative selection	9763430
148819603	148819626	7	+	27869803	PATU8988S	viability after 35 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.11109887736043489	[229]	[120,78,NaN]	1	hSpCas9	negative selection	9845874
148827230	148827253	7	+	27869803	PATU8988S	viability after 35 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.1444492218152078	[446]	[108,216,NaN]	-1	hSpCas9	negative selection	9845875
148828739	148828762	7	-	27869803	PATU8988S	viability after 35 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.18398339473890424	[249]	[62,165,NaN]	2	hSpCas9	negative selection	9845876
148836827	148836850	7	-	27869803	PATU8988S	viability after 35 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.9590938591326499	[346]	[356,185,NaN]	8	hSpCas9	negative selection	9845877
148846469	148846492	7	-	27869803	PATU8988S	viability after 35 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	-0.004111667446538958	[456]	[197,168,NaN]	0	hSpCas9	negative selection	9845878
148847243	148847266	7	+	27869803	PATU8988S	viability after 35 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.423930565637059	[1030]	[587,525,NaN]	5	hSpCas9	negative selection	9845879
148819603	148819626	7	+	27869803	PATU8988S	viability after 31 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.21484178115607255	[229]	[94,120,NaN]	2	hSpCas9	negative selection	9928323
148827230	148827253	7	+	27869803	PATU8988S	viability after 31 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-0.6139130036979108	[446]	[42,209,NaN]	-6	hSpCas9	negative selection	9928324
148828739	148828762	7	-	27869803	PATU8988S	viability after 31 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.1779536582968968	[249]	[77,100,NaN]	-2	hSpCas9	negative selection	9928325
148836827	148836850	7	-	27869803	PATU8988S	viability after 31 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.7583475948247007	[346]	[281,172,NaN]	8	hSpCas9	negative selection	9928326
148846469	148846492	7	-	27869803	PATU8988S	viability after 31 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.1871557394461025	[456]	[144,286,NaN]	2	hSpCas9	negative selection	9928327
148847243	148847266	7	+	27869803	PATU8988S	viability after 31 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	0.4080109894951728	[1030]	[526,568,NaN]	5	hSpCas9	negative selection	9928328
148819603	148819626	7	+	27869803	HPAFII	viability after 35 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	-0.04749771600140673	[117]	[14,105,NaN]	0	hSpCas9	negative selection	10010772
148827230	148827253	7	+	27869803	HPAFII	viability after 35 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-4.630427402108431	[186]	[0,6,NaN]	-9	hSpCas9	negative selection	10010773
148828739	148828762	7	-	27869803	HPAFII	viability after 35 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-1.6621348804209786	[131]	[14,27,NaN]	-7	hSpCas9	negative selection	10010774
148836827	148836850	7	-	27869803	HPAFII	viability after 35 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.34990790667282556	[139]	[158,12,NaN]	2	hSpCas9	negative selection	10010775
148846469	148846492	7	-	27869803	HPAFII	viability after 35 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	0.7036822839546688	[171]	[241,28,NaN]	4	hSpCas9	negative selection	10010776
148847243	148847266	7	+	27869803	HPAFII	viability after 35 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.2708504608587459	[430]	[478,579,NaN]	8	hSpCas9	negative selection	10010777
148819603	148819626	7	+	27869803	HPAFII	viability after 31 days	TGGTAACACTGTGGTCCACAAGG	EZH2	ENSG00000106462	0.12122553622698962	[117]	[27,119,NaN]	0	hSpCas9	negative selection	10093221
148827230	148827253	7	+	27869803	HPAFII	viability after 31 days	TCAGAAGGAAATTTCCGAGGTGG	EZH2	ENSG00000106462	-2.451562687729903	[186]	[0,38,NaN]	-8	hSpCas9	negative selection	10093222
148828739	148828762	7	-	27869803	HPAFII	viability after 31 days	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.8952910907597391	[131]	[35,43,NaN]	-5	hSpCas9	negative selection	10093223
148836827	148836850	7	-	27869803	HPAFII	viability after 31 days	CAGTCGCCTATTGTACCAGCTGG	EZH2	ENSG00000106462	0.25637302267380335	[139]	[123,60,NaN]	1	hSpCas9	negative selection	10093224
148846469	148846492	7	-	27869803	HPAFII	viability after 31 days	CTCATTGCGCGGGACTAGGGAGG	EZH2	ENSG00000106462	1.0412433022202814	[171]	[324,60,NaN]	7	hSpCas9	negative selection	10093225
148847243	148847266	7	+	27869803	HPAFII	viability after 31 days	ACACGCTTCCGCCAACAAACTGG	EZH2	ENSG00000106462	1.394548059026307	[430]	[611,661,NaN]	8	hSpCas9	negative selection	10093226
148817935	148817958	7	-	28162770	P31FUJ	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-0.07583285807597928	[86]	[96]	0	hSpCas9	negative selection	10152250
148817978	148818001	7	+	28162770	P31FUJ	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.39786145068487483	[369]	[329]	-4	hSpCas9	negative selection	10152251
148846524	148846547	7	-	28162770	P31FUJ	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.949170424792464	[211]	[480]	9	hSpCas9	negative selection	10152252
148817237	148817260	7	+	28162770	P31FUJ	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	3.0451825428853865	[9]	[96]	9	hSpCas9	negative selection	10152253
148809363	148809386	7	-	28162770	P31FUJ	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	0.041372759024615444	[214]	[259]	0	hSpCas9	negative selection	10152254
148847268	148847291	7	-	28162770	P31FUJ	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.5623780036971233	[169]	[294]	6	hSpCas9	negative selection	10152255
148846495	148846518	7	+	28162770	P31FUJ	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	0.34100250642225594	[648]	[965]	4	hSpCas9	negative selection	10152256
148828752	148828775	7	-	28162770	P31FUJ	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	0.17267646643962065	[264]	[350]	1	hSpCas9	negative selection	10152257
148828739	148828762	7	-	28162770	P31FUJ	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.009080722605410707	[309]	[361]	0	hSpCas9	negative selection	10152258
148818031	148818054	7	-	28162770	P31FUJ	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-0.30531470419874673	[101]	[96]	-3	hSpCas9	negative selection	10152259
148817935	148817958	7	-	28162770	TF1	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10321616
148817978	148818001	7	+	28162770	TF1	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10321617
148846524	148846547	7	-	28162770	TF1	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10321618
148817237	148817260	7	+	28162770	TF1	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10321619
148809363	148809386	7	-	28162770	TF1	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10321620
148847268	148847291	7	-	28162770	TF1	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10321621
148846495	148846518	7	+	28162770	TF1	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10321622
148828752	148828775	7	-	28162770	TF1	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10321623
148828739	148828762	7	-	28162770	TF1	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10321624
148818031	148818054	7	-	28162770	TF1	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10321625
148817935	148817958	7	-	28162770	SKM1	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-1.3245020385511885	[16]	[11]	-7	hSpCas9	negative selection	10490982
148817978	148818001	7	+	28162770	SKM1	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.003114380096776226	[88]	[156]	0	hSpCas9	negative selection	10490983
148846524	148846547	7	-	28162770	SKM1	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	-0.22374237468739164	[71]	[108]	-2	hSpCas9	negative selection	10490984
148817237	148817260	7	+	28162770	SKM1	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-4.143929792909368	[9]	[0]	-9	hSpCas9	negative selection	10490985
148809363	148809386	7	-	28162770	SKM1	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-3.7527390355848915	[60]	[7]	-9	hSpCas9	negative selection	10490986
148847268	148847291	7	-	28162770	SKM1	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.5851736834838679	[45]	[121]	5	hSpCas9	negative selection	10490987
148846495	148846518	7	+	28162770	SKM1	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-1.971379322060232	[121]	[54]	-8	hSpCas9	negative selection	10490988
148828752	148828775	7	-	28162770	SKM1	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-1.7813597135246597	[69]	[35]	-8	hSpCas9	negative selection	10490989
148828739	148828762	7	-	28162770	SKM1	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-1.2694606749932267	[59]	[43]	-7	hSpCas9	negative selection	10490990
148818031	148818054	7	-	28162770	SKM1	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-1.8726277710919739	[28]	[13]	-8	hSpCas9	negative selection	10490991
148817935	148817958	7	-	28162770	SKM1	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-1.3245020385511885	[16]	[11]	-7	hSpCas9	negative selection	10660348
148817978	148818001	7	+	28162770	SKM1	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.003114380096776226	[88]	[156]	0	hSpCas9	negative selection	10660349
148846524	148846547	7	-	28162770	SKM1	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	-0.22374237468739164	[71]	[108]	-2	hSpCas9	negative selection	10660350
148817237	148817260	7	+	28162770	SKM1	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-4.143929792909368	[9]	[0]	-9	hSpCas9	negative selection	10660351
148809363	148809386	7	-	28162770	SKM1	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-3.7527390355848915	[60]	[7]	-9	hSpCas9	negative selection	10660352
148847268	148847291	7	-	28162770	SKM1	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.5851736834838679	[45]	[121]	5	hSpCas9	negative selection	10660353
148846495	148846518	7	+	28162770	SKM1	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-1.971379322060232	[121]	[54]	-8	hSpCas9	negative selection	10660354
148828752	148828775	7	-	28162770	SKM1	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-1.7813597135246597	[69]	[35]	-8	hSpCas9	negative selection	10660355
148828739	148828762	7	-	28162770	SKM1	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-1.2694606749932267	[59]	[43]	-7	hSpCas9	negative selection	10660356
148818031	148818054	7	-	28162770	SKM1	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-1.8726277710919739	[28]	[13]	-8	hSpCas9	negative selection	10660357
148817935	148817958	7	-	28162770	PL21	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	1.4049594063778184	[58]	[67]	9	hSpCas9	negative selection	10829714
148817978	148818001	7	+	28162770	PL21	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	1.2001396144893202	[286]	[286]	8	hSpCas9	negative selection	10829715
148846524	148846547	7	-	28162770	PL21	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.8568378688093907	[254]	[200]	7	hSpCas9	negative selection	10829716
148817237	148817260	7	+	28162770	PL21	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	1.0891083021005763	[26]	[24]	8	hSpCas9	negative selection	10829717
148809363	148809386	7	-	28162770	PL21	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	1.2441947945672553	[257]	[265]	8	hSpCas9	negative selection	10829718
148847268	148847291	7	-	28162770	PL21	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.9152585063572776	[172]	[141]	7	hSpCas9	negative selection	10829719
148846495	148846518	7	+	28162770	PL21	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	1.4580610969294616	[423]	[506]	9	hSpCas9	negative selection	10829720
148828752	148828775	7	-	28162770	PL21	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	1.4099319990461343	[229]	[265]	9	hSpCas9	negative selection	10829721
148828739	148828762	7	-	28162770	PL21	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	1.381977937475133	[133]	[151]	9	hSpCas9	negative selection	10829722
148818031	148818054	7	-	28162770	PL21	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	0.8032494619207358	[78]	[59]	7	hSpCas9	negative selection	10829723
148817935	148817958	7	-	28162770	P31FUJ	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-0.07583285807597928	[86]	[96]	0	hSpCas9	negative selection	10999080
148817978	148818001	7	+	28162770	P31FUJ	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.39786145068487483	[369]	[329]	-4	hSpCas9	negative selection	10999081
148846524	148846547	7	-	28162770	P31FUJ	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.949170424792464	[211]	[480]	9	hSpCas9	negative selection	10999082
148817237	148817260	7	+	28162770	P31FUJ	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	3.0451825428853865	[9]	[96]	9	hSpCas9	negative selection	10999083
148809363	148809386	7	-	28162770	P31FUJ	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	0.041372759024615444	[214]	[259]	0	hSpCas9	negative selection	10999084
148847268	148847291	7	-	28162770	P31FUJ	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.5623780036971233	[169]	[294]	6	hSpCas9	negative selection	10999085
148846495	148846518	7	+	28162770	P31FUJ	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	0.34100250642225594	[648]	[965]	4	hSpCas9	negative selection	10999086
148828752	148828775	7	-	28162770	P31FUJ	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	0.17267646643962065	[264]	[350]	1	hSpCas9	negative selection	10999087
148828739	148828762	7	-	28162770	P31FUJ	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.009080722605410707	[309]	[361]	0	hSpCas9	negative selection	10999088
148818031	148818054	7	-	28162770	P31FUJ	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-0.30531470419874673	[101]	[96]	-3	hSpCas9	negative selection	10999089
148817935	148817958	7	-	28162770	OCIAML5	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-0.9026926439339649	[28]	[27]	-5	hSpCas9	negative selection	11168446
148817978	148818001	7	+	28162770	OCIAML5	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.2775508575779565	[230]	[343]	-2	hSpCas9	negative selection	11168447
148846524	148846547	7	-	28162770	OCIAML5	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.3210823314526017	[148]	[335]	2	hSpCas9	negative selection	11168448
148817237	148817260	7	+	28162770	OCIAML5	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-2.2443839936427574	[20]	[7]	-8	hSpCas9	negative selection	11168449
148809363	148809386	7	-	28162770	OCIAML5	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-1.427181285628806	[72]	[48]	-7	hSpCas9	negative selection	11168450
148847268	148847291	7	-	28162770	OCIAML5	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	-0.921607504117074	[169]	[161]	-5	hSpCas9	negative selection	11168451
148846495	148846518	7	+	28162770	OCIAML5	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.744560945396012	[348]	[375]	-5	hSpCas9	negative selection	11168452
148828752	148828775	7	-	28162770	OCIAML5	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.21526513862322283	[163]	[254]	-1	hSpCas9	negative selection	11168453
148828739	148828762	7	-	28162770	OCIAML5	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.8073282560987125	[126]	[130]	-5	hSpCas9	negative selection	11168454
148818031	148818054	7	-	28162770	OCIAML5	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-1.4621200525479836	[57]	[37]	-7	hSpCas9	negative selection	11168455
148817935	148817958	7	-	28162770	EOL1	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-0.48353696706654237	[137]	[51]	-4	hSpCas9	negative selection	11337812
148817978	148818001	7	+	28162770	EOL1	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.2656746441050055	[339]	[148]	-2	hSpCas9	negative selection	11337813
148846524	148846547	7	-	28162770	EOL1	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	-0.2676300367189055	[440]	[192]	-2	hSpCas9	negative selection	11337814
148817237	148817260	7	+	28162770	EOL1	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	1.6178864333364829	[46]	[75]	9	hSpCas9	negative selection	11337815
148809363	148809386	7	-	28162770	EOL1	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-0.059332563066188504	[444]	[224]	0	hSpCas9	negative selection	11337816
148847268	148847291	7	-	28162770	EOL1	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.7631536276125784	[273]	[244]	6	hSpCas9	negative selection	11337817
148846495	148846518	7	+	28162770	EOL1	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	0.7572530261728943	[547]	[487]	6	hSpCas9	negative selection	11337818
148828752	148828775	7	-	28162770	EOL1	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	0.1088050640202114	[344]	[195]	1	hSpCas9	negative selection	11337819
148828739	148828762	7	-	28162770	EOL1	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	0.5711871688465149	[289]	[226]	5	hSpCas9	negative selection	11337820
148818031	148818054	7	-	28162770	EOL1	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-0.01995711583776183	[101]	[52]	0	hSpCas9	negative selection	11337821
148817935	148817958	7	-	28162770	MOLM13	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	0.3862055839508707	[108]	[102]	3	hSpCas9	negative selection	11507178
148817978	148818001	7	+	28162770	MOLM13	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-0.6203971508733762	[437]	[205]	-4	hSpCas9	negative selection	11507179
148846524	148846547	7	-	28162770	MOLM13	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	-0.7042298333106454	[328]	[145]	-4	hSpCas9	negative selection	11507180
148817237	148817260	7	+	28162770	MOLM13	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-4.780038131899007	[37]	[0]	-9	hSpCas9	negative selection	11507181
148809363	148809386	7	-	28162770	MOLM13	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-5.567734528186143	[327]	[4]	-9	hSpCas9	negative selection	11507182
148847268	148847291	7	-	28162770	MOLM13	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	-0.5054754919519544	[321]	[163]	-3	hSpCas9	negative selection	11507183
148846495	148846518	7	+	28162770	MOLM13	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-2.0733168430416398	[616]	[105]	-7	hSpCas9	negative selection	11507184
148828752	148828775	7	-	28162770	MOLM13	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-1.09153802706944	[335]	[113]	-5	hSpCas9	negative selection	11507185
148828739	148828762	7	-	28162770	MOLM13	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.45119062307185354	[311]	[164]	-3	hSpCas9	negative selection	11507186
148818031	148818054	7	-	28162770	MOLM13	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-2.6919819552338105	[142]	[15]	-8	hSpCas9	negative selection	11507187
148817935	148817958	7	-	28162770	HEL	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-1.7926473126702893	[118]	[21]	-7	hSpCas9	negative selection	11676544
148817978	148818001	7	+	28162770	HEL	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	0.11886484067860698	[288]	[200]	1	hSpCas9	negative selection	11676545
148846524	148846547	7	-	28162770	HEL	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.8733517601417733	[299]	[351]	7	hSpCas9	negative selection	11676546
148817237	148817260	7	+	28162770	HEL	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	0.6933649050703252	[27]	[28]	6	hSpCas9	negative selection	11676547
148809363	148809386	7	-	28162770	HEL	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-1.7026482357109942	[309]	[60]	-7	hSpCas9	negative selection	11676548
148847268	148847291	7	-	28162770	HEL	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	1.0690035867024548	[255]	[343]	8	hSpCas9	negative selection	11676549
148846495	148846518	7	+	28162770	HEL	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.5117074373730219	[393]	[176]	-3	hSpCas9	negative selection	11676550
148828752	148828775	7	-	28162770	HEL	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	0.32562775341077044	[298]	[239]	2	hSpCas9	negative selection	11676551
148828739	148828762	7	-	28162770	HEL	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.1540079904912663	[270]	[155]	-1	hSpCas9	negative selection	11676552
148818031	148818054	7	-	28162770	HEL	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	1.4884106856090633	[68]	[123]	9	hSpCas9	negative selection	11676553
148817935	148817958	7	-	28162770	MV411	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-0.042069066412209644	[65]	[53]	0	hSpCas9	negative selection	11845910
148817978	148818001	7	+	28162770	MV411	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	0.5780828627712468	[263]	[331]	5	hSpCas9	negative selection	11845911
148846524	148846547	7	-	28162770	MV411	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.39868113115901277	[189]	[210]	3	hSpCas9	negative selection	11845912
148817237	148817260	7	+	28162770	MV411	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-4.211994067854522	[21]	[0]	-9	hSpCas9	negative selection	11845913
148809363	148809386	7	-	28162770	MV411	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-6.08048928472603	[240]	[2]	-9	hSpCas9	negative selection	11845914
148847268	148847291	7	-	28162770	MV411	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	-0.7525624492172247	[173]	[86]	-5	hSpCas9	negative selection	11845915
148846495	148846518	7	+	28162770	MV411	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.9712027356925651	[383]	[164]	-6	hSpCas9	negative selection	11845916
148828752	148828775	7	-	28162770	MV411	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-1.2493940396597156	[253]	[89]	-7	hSpCas9	negative selection	11845917
148828739	148828762	7	-	28162770	MV411	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.9462435739121453	[198]	[86]	-6	hSpCas9	negative selection	11845918
148818031	148818054	7	-	28162770	MV411	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-3.5938647031981663	[85]	[5]	-9	hSpCas9	negative selection	11845919
148817935	148817958	7	-	28162770	MONOMAC1	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-1.656468465696851	[76]	[27]	-8	hSpCas9	negative selection	12015276
148817978	148818001	7	+	28162770	MONOMAC1	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	-1.78199934778071	[206]	[68]	-8	hSpCas9	negative selection	12015277
148846524	148846547	7	-	28162770	MONOMAC1	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	-1.3274334843152287	[161]	[73]	-7	hSpCas9	negative selection	12015278
148817237	148817260	7	+	28162770	MONOMAC1	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-4.1039274426680725	[14]	[0]	-9	hSpCas9	negative selection	12015279
148809363	148809386	7	-	28162770	MONOMAC1	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-4.455771115459721	[133]	[6]	-9	hSpCas9	negative selection	12015280
148847268	148847291	7	-	28162770	MONOMAC1	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	-1.4163498754640296	[155]	[66]	-8	hSpCas9	negative selection	12015281
148846495	148846518	7	+	28162770	MONOMAC1	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-1.4552542365955716	[298]	[124]	-8	hSpCas9	negative selection	12015282
148828752	148828775	7	-	28162770	MONOMAC1	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	0.2525738007667164	[133]	[182]	2	hSpCas9	negative selection	12015283
148828739	148828762	7	-	28162770	MONOMAC1	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-1.4803436479196088	[128]	[52]	-8	hSpCas9	negative selection	12015284
148818031	148818054	7	-	28162770	MONOMAC1	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-1.158562699244918	[36]	[18]	-7	hSpCas9	negative selection	12015285
148817935	148817958	7	-	28162770	OCIAML2	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	-0.9126343721212744	[17]	[52]	-6	hSpCas9	negative selection	12184642
148817978	148818001	7	+	28162770	OCIAML2	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	0.114332675478995	[45]	[275]	1	hSpCas9	negative selection	12184643
148846524	148846547	7	-	28162770	OCIAML2	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.06035505442016997	[58]	[340]	0	hSpCas9	negative selection	12184644
148817237	148817260	7	+	28162770	OCIAML2	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-0.35515260782222535	[2]	[12]	-3	hSpCas9	negative selection	12184645
148809363	148809386	7	-	28162770	OCIAML2	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-1.9906368841225475	[37]	[52]	-8	hSpCas9	negative selection	12184646
148847268	148847291	7	-	28162770	OCIAML2	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.11433267547899506	[39]	[239]	1	hSpCas9	negative selection	12184647
148846495	148846518	7	+	28162770	OCIAML2	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.06740162825295082	[68]	[364]	0	hSpCas9	negative selection	12184648
148828752	148828775	7	-	28162770	OCIAML2	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.5731995588827089	[50]	[189]	-4	hSpCas9	negative selection	12184649
148828739	148828762	7	-	28162770	OCIAML2	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.1487017303547989	[32]	[164]	-1	hSpCas9	negative selection	12184650
148818031	148818054	7	-	28162770	OCIAML2	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-1.5775450291586735	[6]	[12]	-7	hSpCas9	negative selection	12184651
148817935	148817958	7	-	28162770	OCIAML3	viability	GGGAAGCAGGGACTGAAACGGGG	EZH2	ENSG00000106462	0.707161894396402	[27]	[137]	6	hSpCas9	negative selection	12354008
148817978	148818001	7	+	28162770	OCIAML3	viability	GATTCCAGCACATTAATGGTGGG	EZH2	ENSG00000106462	0.33473367650601504	[82]	[315]	3	hSpCas9	negative selection	12354009
148846524	148846547	7	-	28162770	OCIAML3	viability	ACCAAGAATGGAAACAGCGAAGG	EZH2	ENSG00000106462	0.7088116316154947	[75]	[374]	6	hSpCas9	negative selection	12354010
148817237	148817260	7	+	28162770	OCIAML3	viability	GGTCCCAATTAACCTAGCAATGG	EZH2	ENSG00000106462	-1.4684767582403042	[10]	[11]	-7	hSpCas9	negative selection	12354011
148809363	148809386	7	-	28162770	OCIAML3	viability	GTGGTGGATGCAACCCGCAAGGG	EZH2	ENSG00000106462	-3.371615218987715	[71]	[20]	-9	hSpCas9	negative selection	12354012
148847268	148847291	7	-	28162770	OCIAML3	viability	GACTGGGAAGAAATCTGAGAAGG	EZH2	ENSG00000106462	0.19377174339668016	[52]	[182]	1	hSpCas9	negative selection	12354013
148846495	148846518	7	+	28162770	OCIAML3	viability	ACAGAAGTCAGGATGTGCACAGG	EZH2	ENSG00000106462	-0.2193278786614603	[144]	[375]	-2	hSpCas9	negative selection	12354014
148828752	148828775	7	-	28162770	OCIAML3	viability	AGAAAAGCAGAAAGATCTGGAGG	EZH2	ENSG00000106462	-0.18188173646522254	[61]	[164]	-1	hSpCas9	negative selection	12354015
148828739	148828762	7	-	28162770	OCIAML3	viability	GATCTGGAGGATCACCGAGATGG	EZH2	ENSG00000106462	-0.46394709975979026	[52]	[115]	-4	hSpCas9	negative selection	12354016
148818031	148818054	7	-	28162770	OCIAML3	viability	CAGGAGGCCGCAGAAGAGGACGG	EZH2	ENSG00000106462	-2.681470481574503	[16]	[7]	-9	hSpCas9	negative selection	12354017