Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2192
• Symbol:FBLN1
• Description:fibulin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/FBLN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45503022	45503045	22	-	26472758	Jiyoye	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	1.3162017214583828	[89]	[168]	7	hSpCas9	negative selection	56360
45533877	45533900	22	+	26472758	Jiyoye	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	-0.9316265319458852	[42]	[16]	-6	hSpCas9	negative selection	56361
45525576	45525599	22	+	26472758	Jiyoye	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.36361901551913367	[268]	[260]	2	hSpCas9	negative selection	56362
45533804	45533827	22	+	26472758	Jiyoye	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	1.051031571280598	[63]	[99]	7	hSpCas9	negative selection	56363
45535234	45535257	22	-	26472758	Jiyoye	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-1.070146396027313	[141]	[50]	-6	hSpCas9	negative selection	56364
45550598	45550621	22	-	26472758	Jiyoye	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	3.86660700014317	[0]	[10]	9	hSpCas9	negative selection	56365
45518695	45518718	22	-	26472758	Jiyoye	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	1.4071753815058734	[44]	[89]	8	hSpCas9	negative selection	56366
45525558	45525581	22	+	26472758	Jiyoye	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	0.7088310813669747	[128]	[158]	5	hSpCas9	negative selection	56367
45531266	45531289	22	+	26472758	Jiyoye	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.2590767425167396	[163]	[147]	2	hSpCas9	negative selection	56368
45533861	45533884	22	+	26472758	Jiyoye	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-2.499715214102645	[59]	[7]	-9	hSpCas9	negative selection	56369
45503022	45503045	22	-	26472758	KBM7	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.46362831449208025	[650,589]	[453,355]	5	hSpCas9	negative selection	247478
45533877	45533900	22	+	26472758	KBM7	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	0.8582303822291324	[65,72]	[62,56]	8	hSpCas9	negative selection	247479
45525576	45525599	22	+	26472758	KBM7	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.04657158346837331	[1058,756]	[448,371]	0	hSpCas9	negative selection	247480
45533804	45533827	22	+	26472758	KBM7	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.3470350448660139	[257,201]	[192,85]	3	hSpCas9	negative selection	247481
45535234	45535257	22	-	26472758	KBM7	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-1.4018068588557482	[180,150]	[49,10]	-7	hSpCas9	negative selection	247482
45550598	45550621	22	-	26472758	KBM7	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	-0.9975493357968315	[146,20]	[20,15]	-6	hSpCas9	negative selection	247483
45518695	45518718	22	-	26472758	KBM7	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	0.24449192730465524	[386,205]	[88,224]	2	hSpCas9	negative selection	247484
45525558	45525581	22	+	26472758	KBM7	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	0.6579768580245839	[1093,974]	[894,651]	7	hSpCas9	negative selection	247485
45531266	45531289	22	+	26472758	KBM7	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.211778420738977	[919,1056]	[606,488]	2	hSpCas9	negative selection	247486
45533861	45533884	22	+	26472758	KBM7	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	0.5063711220722733	[48,41]	[52,9]	5	hSpCas9	negative selection	247487
45503022	45503045	22	-	26472758	Raji	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.5343442020282625	[240]	[80]	5	hSpCas9	negative selection	438596
45533877	45533900	22	+	26472758	Raji	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	0.7183412446277004	[54]	[20]	6	hSpCas9	negative selection	438597
45525576	45525599	22	+	26472758	Raji	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.08036036160705273	[484]	[118]	0	hSpCas9	negative selection	438598
45533804	45533827	22	+	26472758	Raji	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	2.2621061301722416	[52]	[58]	9	hSpCas9	negative selection	438599
45535234	45535257	22	-	26472758	Raji	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.06785517118696216	[110]	[26]	0	hSpCas9	negative selection	438600
45550598	45550621	22	-	26472758	Raji	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	-0.36392218355198946	[60]	[10]	-3	hSpCas9	negative selection	438601
45518695	45518718	22	-	26472758	Raji	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	0.9830554003713978	[108]	[49]	8	hSpCas9	negative selection	438602
45525558	45525581	22	+	26472758	Raji	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.033479000466249964	[515]	[116]	0	hSpCas9	negative selection	438603
45531266	45531289	22	+	26472758	Raji	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	-0.27867489693347847	[459]	[87]	-2	hSpCas9	negative selection	438604
45533861	45533884	22	+	26472758	Raji	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	1.2142987392901108	[12]	[6]	9	hSpCas9	negative selection	438605
45503022	45503045	22	-	26472758	K562	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.7585687607246167	[681]	[973]	6	hSpCas9	negative selection	629714
45533877	45533900	22	+	26472758	K562	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	-0.879316640755798	[145]	[66]	-5	hSpCas9	negative selection	629715
45525576	45525599	22	+	26472758	K562	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.5173299674296477	[684]	[403]	-3	hSpCas9	negative selection	629716
45533804	45533827	22	+	26472758	K562	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.6755758923085677	[177]	[239]	5	hSpCas9	negative selection	629717
45535234	45535257	22	-	26472758	K562	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	1.0453186275867514	[127]	[222]	8	hSpCas9	negative selection	629718
45550598	45550621	22	-	26472758	K562	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.22095975484245756	[61]	[60]	1	hSpCas9	negative selection	629719
45518695	45518718	22	-	26472758	K562	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.5228010822023524	[256]	[150]	-3	hSpCas9	negative selection	629720
45525558	45525581	22	+	26472758	K562	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	0.010067076536737884	[746]	[634]	0	hSpCas9	negative selection	629721
45531266	45531289	22	+	26472758	K562	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.6680693572499987	[834]	[1119]	5	hSpCas9	negative selection	629722
45533861	45533884	22	+	26472758	K562	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	1.0517736497240509	[23]	[41]	8	hSpCas9	negative selection	629723
45518710	45518733	22	+	26627737	DLD1	viability	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.4504402159946097	[420]	[97,77,109]	-4	hSpCas9	negative selection	818279
45523130	45523153	22	+	26627737	DLD1	viability	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.21165301465152675	[943]	[374,349,305]	2	hSpCas9	negative selection	818280
45525600	45525623	22	+	26627737	DLD1	viability	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.5652081750041573	[723]	[303,558,175]	5	hSpCas9	negative selection	818281
45527948	45527971	22	+	26627737	DLD1	viability	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.656248007722203	[119]	[75,43,56]	6	hSpCas9	negative selection	818282
45531303	45531326	22	+	26627737	DLD1	viability	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.45084756301812323	[150]	[10,96,83]	4	hSpCas9	negative selection	818283
45533088	45533111	22	+	26627737	DLD1	viability	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.44918557841086026	[1300]	[521,166,211]	-4	hSpCas9	negative selection	818284
45518710	45518733	22	+	26627737	GBM cells	viability after 5 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.2735936365483883	[144]	[91,95]	4	hSpCas9	negative selection	900594
45523130	45523153	22	+	26627737	GBM cells	viability after 5 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.10161049488121354	[589]	[329,348]	1	hSpCas9	negative selection	900595
45525600	45525623	22	+	26627737	GBM cells	viability after 5 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.5350550995324047	[239]	[206,165]	7	hSpCas9	negative selection	900596
45527948	45527971	22	+	26627737	GBM cells	viability after 5 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	-0.29986598922881225	[100]	[35,51]	-5	hSpCas9	negative selection	900597
45531303	45531326	22	+	26627737	GBM cells	viability after 5 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.14999572559526086	[149]	[74,69]	-2	hSpCas9	negative selection	900598
45533088	45533111	22	+	26627737	GBM cells	viability after 5 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.28078451022933015	[362]	[215,256]	4	hSpCas9	negative selection	900599
45518710	45518733	22	+	26627737	GBM cells	viability after 13 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.3097419319664112	[144]	[91,101]	4	hSpCas9	negative selection	982909
45523130	45523153	22	+	26627737	GBM cells	viability after 13 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.30961839216442577	[589]	[452,350]	4	hSpCas9	negative selection	982910
45525600	45525623	22	+	26627737	GBM cells	viability after 13 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.5366127975696395	[239]	[248,139]	6	hSpCas9	negative selection	982911
45527948	45527971	22	+	26627737	GBM cells	viability after 13 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	-0.04139873894750923	[100]	[71,37]	0	hSpCas9	negative selection	982912
45531303	45531326	22	+	26627737	GBM cells	viability after 13 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.23636720058550004	[149]	[123,72]	3	hSpCas9	negative selection	982913
45533088	45533111	22	+	26627737	GBM cells	viability after 13 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.21102781336632348	[362]	[254,205]	2	hSpCas9	negative selection	982914
45518710	45518733	22	+	26627737	GBM cells	viability after 21 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.6951431522762999	[144]	[44,51]	-6	hSpCas9	negative selection	1065224
45523130	45523153	22	+	26627737	GBM cells	viability after 21 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.2960449190157852	[589]	[415,372]	3	hSpCas9	negative selection	1065225
45525600	45525623	22	+	26627737	GBM cells	viability after 21 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.4150880629146403	[239]	[188,159]	4	hSpCas9	negative selection	1065226
45527948	45527971	22	+	26627737	GBM cells	viability after 21 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	-0.005681939742482767	[100]	[50,57]	0	hSpCas9	negative selection	1065227
45531303	45531326	22	+	26627737	GBM cells	viability after 21 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.5478479325527494	[149]	[115,121]	5	hSpCas9	negative selection	1065228
45533088	45533111	22	+	26627737	GBM cells	viability after 21 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.2037326213378714	[362]	[235,218]	2	hSpCas9	negative selection	1065229
45518710	45518733	22	+	26627737	RPE1	viability after 9 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.26329624324539014	[456]	[93,271]	1	hSpCas9	negative selection	1147539
45523130	45523153	22	+	26627737	RPE1	viability after 9 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.22590511959416748	[2757]	[729,748]	-1	hSpCas9	negative selection	1147540
45525600	45525623	22	+	26627737	RPE1	viability after 9 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.8258273236275635	[2058]	[381,339]	-5	hSpCas9	negative selection	1147541
45527948	45527971	22	+	26627737	RPE1	viability after 9 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.8875604446009357	[211]	[79,177]	6	hSpCas9	negative selection	1147542
45531303	45531326	22	+	26627737	RPE1	viability after 9 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.6554726374254644	[831]	[191,130]	-5	hSpCas9	negative selection	1147543
45533088	45533111	22	+	26627737	RPE1	viability after 9 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-1.1514650165993774	[2224]	[351,263]	-7	hSpCas9	negative selection	1147544
45518710	45518733	22	+	26627737	RPE1	viability after 12 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.25343841620171337	[456]	[85,120]	-2	hSpCas9	negative selection	1229854
45523130	45523153	22	+	26627737	RPE1	viability after 12 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.6411645537776784	[2757]	[461,488]	-4	hSpCas9	negative selection	1229855
45525600	45525623	22	+	26627737	RPE1	viability after 12 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.7769922454912251	[2058]	[367,274]	-5	hSpCas9	negative selection	1229856
45527948	45527971	22	+	26627737	RPE1	viability after 12 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.181653216916501	[211]	[152,103]	7	hSpCas9	negative selection	1229857
45531303	45531326	22	+	26627737	RPE1	viability after 12 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.13163649824460738	[831]	[240,248]	0	hSpCas9	negative selection	1229858
45533088	45533111	22	+	26627737	RPE1	viability after 12 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.6295269251195738	[2224]	[484,281]	-4	hSpCas9	negative selection	1229859
45518710	45518733	22	+	26627737	RPE1	viability after 15 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.25929372833574493	[456]	[169,139]	1	hSpCas9	negative selection	1312169
45523130	45523153	22	+	26627737	RPE1	viability after 15 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.9688534167450435	[2757]	[420,376]	-6	hSpCas9	negative selection	1312170
45525600	45525623	22	+	26627737	RPE1	viability after 15 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.9020319161929256	[2058]	[244,375]	-5	hSpCas9	negative selection	1312171
45527948	45527971	22	+	26627737	RPE1	viability after 15 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.3354719204312	[211]	[75,223]	7	hSpCas9	negative selection	1312172
45531303	45531326	22	+	26627737	RPE1	viability after 15 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.4215012241922008	[831]	[274,353]	2	hSpCas9	negative selection	1312173
45533088	45533111	22	+	26627737	RPE1	viability after 15 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.1558954551771603	[2224]	[680,452]	-1	hSpCas9	negative selection	1312174
45518710	45518733	22	+	26627737	RPE1	viability after 18 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.20913875745199495	[456]	[82,131]	-1	hSpCas9	negative selection	1394484
45523130	45523153	22	+	26627737	RPE1	viability after 18 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.5016646676254461	[2757]	[574,472]	-3	hSpCas9	negative selection	1394485
45525600	45525623	22	+	26627737	RPE1	viability after 18 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.7711785651128653	[2058]	[327,322]	-5	hSpCas9	negative selection	1394486
45527948	45527971	22	+	26627737	RPE1	viability after 18 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.2099182770883978	[211]	[156,105]	7	hSpCas9	negative selection	1394487
45531303	45531326	22	+	26627737	RPE1	viability after 18 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.1576360085998837	[831]	[219,282]	1	hSpCas9	negative selection	1394488
45533088	45533111	22	+	26627737	RPE1	viability after 18 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.5288243482873216	[2224]	[377,456]	-3	hSpCas9	negative selection	1394489
45518710	45518733	22	+	26627737	HeLa	viability after 8 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.3780873023731013	[261]	[117,36,112]	-4	hSpCas9	negative selection	1476799
45523130	45523153	22	+	26627737	HeLa	viability after 8 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.14509683996737066	[1163]	[644,553,503]	1	hSpCas9	negative selection	1476800
45525600	45525623	22	+	26627737	HeLa	viability after 8 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.8981841547704126	[323]	[630,133,114]	7	hSpCas9	negative selection	1476801
45527948	45527971	22	+	26627737	HeLa	viability after 8 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	2.154906566030769	[45]	[100,34,130]	9	hSpCas9	negative selection	1476802
45531303	45531326	22	+	26627737	HeLa	viability after 8 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.4849157420392498	[290]	[56,85,118]	-5	hSpCas9	negative selection	1476803
45533088	45533111	22	+	26627737	HeLa	viability after 8 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.7127572140475459	[979]	[386,257,169]	-6	hSpCas9	negative selection	1476804
45518710	45518733	22	+	26627737	HeLa	viability after 12 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.16484755498138814	[261]	[199,65,29]	-1	hSpCas9	negative selection	1559114
45523130	45523153	22	+	26627737	HeLa	viability after 12 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.10757586428222066	[1163]	[417,611,511]	1	hSpCas9	negative selection	1559115
45525600	45525623	22	+	26627737	HeLa	viability after 12 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	1.2141298176214437	[323]	[418,150,381]	8	hSpCas9	negative selection	1559116
45527948	45527971	22	+	26627737	HeLa	viability after 12 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.939264495821509	[45]	[71,69,76]	9	hSpCas9	negative selection	1559117
45531303	45531326	22	+	26627737	HeLa	viability after 12 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.22500220726394726	[290]	[59,106,139]	-2	hSpCas9	negative selection	1559118
45533088	45533111	22	+	26627737	HeLa	viability after 12 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.8727102220058074	[979]	[248,214,200]	-7	hSpCas9	negative selection	1559119
45518710	45518733	22	+	26627737	HeLa	viability after 15 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-1.5775069384092268	[261]	[41,30,33]	-8	hSpCas9	negative selection	1641429
45523130	45523153	22	+	26627737	HeLa	viability after 15 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.2522041966401507	[1163]	[678,516,489]	2	hSpCas9	negative selection	1641430
45525600	45525623	22	+	26627737	HeLa	viability after 15 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.9346469088463842	[323]	[492,143,104]	7	hSpCas9	negative selection	1641431
45527948	45527971	22	+	26627737	HeLa	viability after 15 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.7092410852189568	[45]	[60,69,51]	9	hSpCas9	negative selection	1641432
45531303	45531326	22	+	26627737	HeLa	viability after 15 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.7297629660179832	[290]	[32,107,73]	-6	hSpCas9	negative selection	1641433
45533088	45533111	22	+	26627737	HeLa	viability after 15 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.5516716493913015	[979]	[371,137,307]	-5	hSpCas9	negative selection	1641434
45518710	45518733	22	+	26627737	HeLa	viability after 18 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-1.5716182696210326	[261]	[28,24,33]	-8	hSpCas9	negative selection	1723744
45523130	45523153	22	+	26627737	HeLa	viability after 18 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.23014486399503298	[1163]	[446,417,489]	2	hSpCas9	negative selection	1723745
45525600	45525623	22	+	26627737	HeLa	viability after 18 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.961531179662322	[323]	[340,117,104]	7	hSpCas9	negative selection	1723746
45527948	45527971	22	+	26627737	HeLa	viability after 18 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.7580838506733232	[45]	[44,57,51]	9	hSpCas9	negative selection	1723747
45531303	45531326	22	+	26627737	HeLa	viability after 18 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.7706559920622058	[290]	[20,85,73]	-6	hSpCas9	negative selection	1723748
45533088	45533111	22	+	26627737	HeLa	viability after 18 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.5413917053848156	[979]	[251,115,307]	-5	hSpCas9	negative selection	1723749
45518710	45518733	22	+	26627737	HCT116	viability after 6 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-3.33979652405682	[361]	[13,0]	-9	hSpCas9	negative selection	1806059
45523130	45523153	22	+	26627737	HCT116	viability after 6 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.7321456448311578	[1257]	[323,330]	4	hSpCas9	negative selection	1806060
45525600	45525623	22	+	26627737	HCT116	viability after 6 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	1.2088062249187028	[959]	[353,345]	6	hSpCas9	negative selection	1806061
45527948	45527971	22	+	26627737	HCT116	viability after 6 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.38230894362081025	[190]	[13,52]	2	hSpCas9	negative selection	1806062
45531303	45531326	22	+	26627737	HCT116	viability after 6 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	2.2344334291307026	[169]	[215,75]	9	hSpCas9	negative selection	1806063
45533088	45533111	22	+	26627737	HCT116	viability after 6 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	1.430716960029351	[831]	[612,208]	7	hSpCas9	negative selection	1806064
45518710	45518733	22	+	26627737	HCT116	viability after 8 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.0909419345692204	[215]	[134,81,162]	1	hSpCas9	negative selection	1888374
45523130	45523153	22	+	26627737	HCT116	viability after 8 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.53366971593127	[1260]	[452,464,520]	-6	hSpCas9	negative selection	1888375
45525600	45525623	22	+	26627737	HCT116	viability after 8 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.6142098738097482	[315]	[336,290,173]	6	hSpCas9	negative selection	1888376
45527948	45527971	22	+	26627737	HCT116	viability after 8 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	2.154454125833099	[38]	[114,128,43]	9	hSpCas9	negative selection	1888377
45531303	45531326	22	+	26627737	HCT116	viability after 8 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.2672824340790628	[183]	[97,72,81]	-3	hSpCas9	negative selection	1888378
45533088	45533111	22	+	26627737	HCT116	viability after 8 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.6743542399503955	[439]	[296,378,481]	6	hSpCas9	negative selection	1888379
45518710	45518733	22	+	26627737	HCT116	viability after 9 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.27116970812933017	[361]	[119,113]	2	hSpCas9	negative selection	1970689
45523130	45523153	22	+	26627737	HCT116	viability after 9 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.014618144742955641	[1257]	[317,343]	0	hSpCas9	negative selection	1970690
45525600	45525623	22	+	26627737	HCT116	viability after 9 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.8778480259547577	[959]	[88,772]	6	hSpCas9	negative selection	1970691
45527948	45527971	22	+	26627737	HCT116	viability after 9 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.5127489410420738	[190]	[74,70]	4	hSpCas9	negative selection	1970692
45531303	45531326	22	+	26627737	HCT116	viability after 9 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	3.015766253139856	[169]	[217,484]	9	hSpCas9	negative selection	1970693
45533088	45533111	22	+	26627737	HCT116	viability after 9 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.05471192244387246	[831]	[233,197]	0	hSpCas9	negative selection	1970694
45518710	45518733	22	+	26627737	HCT116	viability after 12 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.5191226886017807	[215]	[161,117,206]	5	hSpCas9	negative selection	2053004
45523130	45523153	22	+	26627737	HCT116	viability after 12 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.7398609028236149	[1260]	[394,412,382]	-7	hSpCas9	negative selection	2053005
45525600	45525623	22	+	26627737	HCT116	viability after 12 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.5011986473075917	[315]	[162,297,251]	5	hSpCas9	negative selection	2053006
45527948	45527971	22	+	26627737	HCT116	viability after 12 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.6255706877408709	[38]	[24,100,67]	9	hSpCas9	negative selection	2053007
45531303	45531326	22	+	26627737	HCT116	viability after 12 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.17231703296631562	[183]	[65,119,73]	-2	hSpCas9	negative selection	2053008
45533088	45533111	22	+	26627737	HCT116	viability after 12 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.41386293773639005	[439]	[196,310,425]	4	hSpCas9	negative selection	2053009
45518710	45518733	22	+	26627737	HCT116	viability after 15 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.1937713812277448	[215]	[122,83,119]	-2	hSpCas9	negative selection	2135319
45523130	45523153	22	+	26627737	HCT116	viability after 15 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.9593247680735295	[1260]	[462,345,319]	-7	hSpCas9	negative selection	2135320
45525600	45525623	22	+	26627737	HCT116	viability after 15 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.15543604471578282	[315]	[193,260,150]	1	hSpCas9	negative selection	2135321
45527948	45527971	22	+	26627737	HCT116	viability after 15 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.3702014126012587	[38]	[60,48,63]	9	hSpCas9	negative selection	2135322
45531303	45531326	22	+	26627737	HCT116	viability after 15 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.6312316275901465	[183]	[64,47,90]	-6	hSpCas9	negative selection	2135323
45533088	45533111	22	+	26627737	HCT116	viability after 15 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.6460531321072935	[439]	[477,294,422]	6	hSpCas9	negative selection	2135324
45518710	45518733	22	+	26627737	HCT116	viability after 18 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.22777768333631077	[215]	[105,161,94]	2	hSpCas9	negative selection	2217634
45523130	45523153	22	+	26627737	HCT116	viability after 18 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	-0.7646062529932465	[1260]	[399,431,233]	-6	hSpCas9	negative selection	2217635
45525600	45525623	22	+	26627737	HCT116	viability after 18 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	1.1361755597821697	[315]	[310,408,279]	8	hSpCas9	negative selection	2217636
45527948	45527971	22	+	26627737	HCT116	viability after 18 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	1.8033182988879897	[38]	[11,22,169]	9	hSpCas9	negative selection	2217637
45531303	45531326	22	+	26627737	HCT116	viability after 18 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.09948050931049668	[183]	[109,79,96]	0	hSpCas9	negative selection	2217638
45533088	45533111	22	+	26627737	HCT116	viability after 18 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.8303691558752124	[439]	[328,301,514]	6	hSpCas9	negative selection	2217639
45502656	45502679	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTGGGGGCATCCGGCCCGAAGG	FBLN1	ENSG00000077942	1.9976475730216825	[9,31]	[30,5]	7	dCas9-VP64	positive selection	2440116
45502729	45502752	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGGGCGCGCGCCCACGGCTGG	FBLN1	ENSG00000077942	0.3014521013714361	[37,39]	[8,10]	1	dCas9-VP64	positive selection	2440117
45502698	45502721	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGGATCCCAGACTTCCCCGG	FBLN1	ENSG00000077942	0.9153264013504054	[96,114]	[11,77]	3	dCas9-VP64	positive selection	2440118
45525085	45525108	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAGAAAGAGAGAAAGGGAAAG	FBLN1	ENSG00000077942	2.8213484780077707	[6,17]	[22,15]	8	dCas9-VP64	positive selection	2442950
45502656	45502679	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTGGGGGCATCCGGCCCGAAGG	FBLN1	ENSG00000077942	-0.33342271673120294	[99,246]	[14,71]	-3	dCas9-VP64	positive selection	2535371
45502729	45502752	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGGGCGCGCGCCCACGGCTGG	FBLN1	ENSG00000077942	2.47126310481278	[53,16]	[128,4]	9	dCas9-VP64	positive selection	2535372
45502698	45502721	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGGATCCCAGACTTCCCCGG	FBLN1	ENSG00000077942	0.17269857004689437	[171,182]	[34,92]	1	dCas9-VP64	positive selection	2535373
45525085	45525108	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAGAAAGAGAGAAAGGGAAAG	FBLN1	ENSG00000077942	1.8482133385132702	[123,91]	[232,27]	8	dCas9-VP64	positive selection	2538205
45533862	45533885	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	0.6113795224957157	[3,2]	[3,4]	9	hSpCas9	positive selection	2988045
45531304	45531327	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.6264158838415457	[3,3]	[3,0]	-7	hSpCas9	positive selection	2988046
45535234	45535257	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.18432102858514393	[3,3]	[4,2]	4	hSpCas9	positive selection	2988047
45518669	45518692	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTCCCTGCACAGTGGACGCGG	FBLN1	ENSG00000077942	0.3178866102288443	[4,4]	[4,4]	6	hSpCas9	positive selection	2988048
45533862	45533885	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-0.09425747535987689	[3,3]	[3,1]	-1	hSpCas9	positive selection	3055903
45531304	45531327	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.4079350330195646	[3,3]	[3,2]	7	hSpCas9	positive selection	3055904
45535234	45535257	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-0.019804251371810716	[3,3]	[3,1]	0	hSpCas9	positive selection	3055905
45518669	45518692	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTCCCTGCACAGTGGACGCGG	FBLN1	ENSG00000077942	0.8981927867724986	[4,4]	[3,7]	9	hSpCas9	positive selection	3055906
45525639	45525662		-	24336571	A375	resistance to PLX after 7 days	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	-0.03777565881108069	[37,38]	[37,35]	-1	hSpCas9	positive selection	3114113
45527974	45527997		-	24336571	A375	resistance to PLX after 7 days	GCCCCCGACATCCAAATCTCCGG	FBLN1	ENSG00000077942	0.0919224693712255	[35,39]	[43,36]	3	hSpCas9	positive selection	3114114
45525665	45525688		-	24336571	A375	resistance to PLX after 7 days	GGCTCTCACCTTCACAAATGTGG	FBLN1	ENSG00000077942	-0.3397045087825165	[15,14]	[10,12]	-8	hSpCas9	positive selection	3114115
45527987	45528010		+	24336571	A375	resistance to PLX after 7 days	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.06509437450623376	[11,13]	[12,13]	2	hSpCas9	positive selection	3114116
45525639	45525662		-	24336571	A375	resistance to PLX after 14 days	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	-0.2832407623549471	[37,37]	[11,15]	-3	hSpCas9	positive selection	3171906
45527974	45527997		-	24336571	A375	resistance to PLX after 14 days	GCCCCCGACATCCAAATCTCCGG	FBLN1	ENSG00000077942	0.7114998873058909	[39,40]	[26,34]	6	hSpCas9	positive selection	3171907
45525665	45525688		-	24336571	A375	resistance to PLX after 14 days	GGCTCTCACCTTCACAAATGTGG	FBLN1	ENSG00000077942	-0.2749471858765506	[13,12]	[5,3]	-3	hSpCas9	positive selection	3171908
45527987	45528010		+	24336571	A375	resistance to PLX after 14 days	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.24114249485649564	[11,13]	[4,4]	-3	hSpCas9	positive selection	3171909
45525639	45525662		-	24336571	A375	viability after 7 days	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5447521279931045	[27]	[37,38]	7	hSpCas9	negative selection	3229699
45527974	45527997		-	24336571	A375	viability after 7 days	GCCCCCGACATCCAAATCTCCGG	FBLN1	ENSG00000077942	-0.18398680602040285	[45]	[35,39]	-3	hSpCas9	negative selection	3229700
45525665	45525688		-	24336571	A375	viability after 7 days	GGCTCTCACCTTCACAAATGTGG	FBLN1	ENSG00000077942	-0.6813080089692175	[26]	[15,14]	-7	hSpCas9	negative selection	3229701
45527987	45528010		+	24336571	A375	viability after 7 days	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.0056046118843308835	[13]	[11,13]	0	hSpCas9	negative selection	3229702
45525639	45525662		-	24336571	A375	viability after 14 days	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5393261621519458	[27]	[37,37]	7	hSpCas9	negative selection	3287492
45527974	45527997		-	24336571	A375	viability after 14 days	GCCCCCGACATCCAAATCTCCGG	FBLN1	ENSG00000077942	-0.07434447322878812	[45]	[39,40]	-1	hSpCas9	negative selection	3287493
45525665	45525688		-	24336571	A375	viability after 14 days	GGCTCTCACCTTCACAAATGTGG	FBLN1	ENSG00000077942	-0.8730619361751667	[26]	[13,12]	-8	hSpCas9	negative selection	3287494
45527987	45528010		+	24336571	A375	viability after 14 days	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.05066641633812742	[13]	[11,13]	0	hSpCas9	negative selection	3287495
45541341	45541364	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.4837021467007808	[95,122]	[0,0]	2	hSpCas9	positive selection	3349596
45541264	45541287	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.3570513269300386	[111,126]	[0,0]	1	hSpCas9	positive selection	3349597
45527987	45528010	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	2.0866156423059814	[38,32]	[0,0]	7	hSpCas9	positive selection	3349598
45527966	45527989	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	-1.5075453792902558	[434,434]	[0,0]	-8	hSpCas9	positive selection	3368801
45525611	45525634	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	0.5991147286940403	[100,100]	[0,0]	3	hSpCas9	positive selection	3368802
45525639	45525662	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	2.556886493304743	[25,25]	[0,0]	8	hSpCas9	positive selection	3368803
45533861	45533884	22	+	26780180	HT29	viability (Avana library 4 designs)	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	1.96135133948724	[]	[]	7	hSpCas9	negative selection	3424938
45531303	45531326	22	+	26780180	HT29	viability (Avana library 4 designs)	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.693967258455665	[]	[]	2	hSpCas9	negative selection	3424939
45535234	45535257	22	-	26780180	HT29	viability (Avana library 4 designs)	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	1.05683393047378	[]	[]	4	hSpCas9	negative selection	3424940
45518668	45518691	22	+	26780180	HT29	viability (Avana library 4 designs)	TCTTCCCTGCACAGTGGACGCGG	FBLN1	ENSG00000077942	0.77684690099415	[]	[]	3	hSpCas9	negative selection	3424941
45518668	45518691	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTCCCTGCACAGTGGACGCGG	FBLN1	ENSG00000077942	5.00123951890818	[]	[]	8	hSpCas9	negative selection	3506829
45533861	45533884	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	7.59964367123594	[]	[]	9	hSpCas9	negative selection	3506830
45535234	45535257	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	2.41707707662837	[]	[]	3	hSpCas9	negative selection	3506831
45531303	45531326	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	3.0141124012109	[]	[]	4	hSpCas9	negative selection	3506832
45503019	45503042	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCCGCTGCTGCTGCTCGGCGG	FBLN1	ENSG00000077942	4.74321989490613	[]	[]	7	hSpCas9	negative selection	3506833
45525637	45525660	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCTGGCGTTGTCACCGTGGGG	FBLN1	ENSG00000077942	5.84644064496987	[]	[]	9	hSpCas9	negative selection	3506834
45518668	45518691	22	+	26780180	A375	viability (Avana lentiGuide)	TCTTCCCTGCACAGTGGACGCGG	FBLN1	ENSG00000077942	-1.7394835651708	[]	[]	-3	hSpCas9	negative selection	3615488
45533861	45533884	22	+	26780180	A375	viability (Avana lentiGuide)	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-1.21892289202972	[]	[]	-2	hSpCas9	negative selection	3615489
45535234	45535257	22	-	26780180	A375	viability (Avana lentiGuide)	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-3.29850450852026	[]	[]	-6	hSpCas9	negative selection	3615490
45531303	45531326	22	+	26780180	A375	viability (Avana lentiGuide)	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	5.50821858240851	[]	[]	5	hSpCas9	negative selection	3615491
45503019	45503042	22	+	26780180	A375	viability (Avana lentiGuide)	CTTCCGCTGCTGCTGCTCGGCGG	FBLN1	ENSG00000077942	-1.65267663333447	[]	[]	-3	hSpCas9	negative selection	3615492
45525637	45525660	22	-	26780180	A375	viability (Avana lentiGuide)	AGGCTGGCGTTGTCACCGTGGGG	FBLN1	ENSG00000077942	-1.59221311242423	[]	[]	-3	hSpCas9	negative selection	3615493
45518668	45518691	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTCCCTGCACAGTGGACGCGG	FBLN1	ENSG00000077942	0.22851031506940023	[5]	[7,6]	6	hSpCas9	positive selection	3724147
45533861	45533884	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	0.28268664928727694	[4]	[6,4]	7	hSpCas9	positive selection	3724148
45535234	45535257	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-0.16902166031474855	[4]	[4,3]	-3	hSpCas9	positive selection	3724149
45531303	45531326	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.2629137693867699	[5]	[6,6]	7	hSpCas9	positive selection	3724150
45503019	45503042	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCCGCTGCTGCTGCTCGGCGG	FBLN1	ENSG00000077942	0.20589867194922662	[4]	[5,4]	6	hSpCas9	positive selection	3724151
45525637	45525660	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCTGGCGTTGTCACCGTGGGG	FBLN1	ENSG00000077942	0.43042559443714506	[4]	[5,6]	9	hSpCas9	positive selection	3724152
45518668	45518691	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTCCCTGCACAGTGGACGCGG	FBLN1	ENSG00000077942	0.26990959019726124	[6]	[7,5]	7	hSpCas9	positive selection	3832754
45533861	45533884	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-0.46899969267401476	[5]	[3,2]	-6	hSpCas9	positive selection	3832755
45535234	45535257	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-0.47911510166915316	[5]	[2,2]	-6	hSpCas9	positive selection	3832756
45531303	45531326	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.3103893600826119	[5]	[5,5]	8	hSpCas9	positive selection	3832757
45503019	45503042	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCCGCTGCTGCTGCTCGGCGG	FBLN1	ENSG00000077942	0.15956880224014516	[5]	[5,4]	4	hSpCas9	positive selection	3832758
45525637	45525660	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCTGGCGTTGTCACCGTGGGG	FBLN1	ENSG00000077942	0.1478478465249902	[4]	[5,3]	3	hSpCas9	positive selection	3832759
45527966	45527989	22	-	26780180	A375	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	1.25764288996108	[]	[]	6	hSpCas9	negative selection	3940010
45525639	45525662	22	-	26780180	A375	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.209006400942306	[]	[]	0	hSpCas9	negative selection	3940011
45541341	45541364	22	-	26780180	A375	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.0989670462644586	[]	[]	-3	hSpCas9	negative selection	3940012
45525611	45525634	22	-	26780180	A375	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	1.23211009660523	[]	[]	6	hSpCas9	negative selection	3940013
45527987	45528010	22	+	26780180	A375	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.55193325698397	[]	[]	1	hSpCas9	negative selection	3940014
45541264	45541287	22	-	26780180	A375	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.379105505379309	[]	[]	0	hSpCas9	negative selection	3940015
45527966	45527989	22	-	26780180	HT29	viability (GeCKOv2 library)	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.859163173440414	[]	[]	3	hSpCas9	negative selection	4047976
45525639	45525662	22	-	26780180	HT29	viability (GeCKOv2 library)	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.57423610763322	[]	[]	2	hSpCas9	negative selection	4047977
45541341	45541364	22	-	26780180	HT29	viability (GeCKOv2 library)	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.322022582695934	[]	[]	0	hSpCas9	negative selection	4047978
45525611	45525634	22	-	26780180	HT29	viability (GeCKOv2 library)	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	1.72554291801439	[]	[]	8	hSpCas9	negative selection	4047979
45527987	45528010	22	+	26780180	HT29	viability (GeCKOv2 library)	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.900180464821815	[]	[]	4	hSpCas9	negative selection	4047980
45541264	45541287	22	-	26780180	HT29	viability (GeCKOv2 library)	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.990213968640142	[]	[]	4	hSpCas9	negative selection	4047981
45525639	45525662	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5368373537992972	[5]	[7,3]	9	hSpCas9	positive selection	4137107
45527974	45527997	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCCCCGACATCCAAATCTCCGG	FBLN1	ENSG00000077942	0.23160297945710978	[5]	[3,4]	6	hSpCas9	positive selection	4137108
45525665	45525688	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCTCTCACCTTCACAAATGTGG	FBLN1	ENSG00000077942	-0.07761635031772234	[3]	[2,2]	-2	hSpCas9	positive selection	4137109
45527987	45528010	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.02905387165586809	[3]	[2,2]	0	hSpCas9	positive selection	4137110
45525639	45525662	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.9941906445148707	[5]	[4,4,5,4]	7	hSpCas9	positive selection	4201129
45527974	45527997	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCCCCGACATCCAAATCTCCGG	FBLN1	ENSG00000077942	0.7278247546925732	[5]	[3,4,2,3]	5	hSpCas9	positive selection	4201130
45525665	45525688	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCTCTCACCTTCACAAATGTGG	FBLN1	ENSG00000077942	0.5443310044223959	[5]	[3,1,1,3]	4	hSpCas9	positive selection	4201131
45527987	45528010	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.6795888512947	[3]	[0,0,1,0]	-8	hSpCas9	positive selection	4201132
45541341	45541364	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.49594254712651087	[2]	[2,2]	8	hSpCas9	positive selection	4270632
45541264	45541287	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.26062488221036434	[3]	[2,2]	5	hSpCas9	positive selection	4270633
45527987	45528010	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.34927854289152216	[1]	[0,0]	-6	hSpCas9	positive selection	4270634
45527966	45527989	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	-0.2432087045492845	[3]	[3,1]	-5	hSpCas9	positive selection	4334896
45525611	45525634	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.2765825423162569	[2]	[1,0]	-5	hSpCas9	positive selection	4334897
45525639	45525662	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.35889342246694356	[0]	[0,0]	7	hSpCas9	positive selection	4334898
45518706	45518728	22	-	27760321	OCIAML3	viability	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.6494343947450332	[654,580]	[268,357]	-6	hSpCas9	negative selection	4400451
45518759	45518781	22	-	27760321	OCIAML3	viability	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.37359383545230435	[392,312]	[302,423]	4	hSpCas9	negative selection	4400452
45525638	45525660	22	-	27760321	OCIAML3	viability	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.5014060559509282	[915,693]	[788,1007]	6	hSpCas9	negative selection	4400453
45527974	45527996	22	+	27760321	OCIAML3	viability	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	-0.3311654955544827	[881,717]	[443,560]	-3	hSpCas9	negative selection	4400454
45531300	45531322	22	-	27760321	OCIAML3	viability	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.41129412305533786	[314,243]	[216,381]	5	hSpCas9	negative selection	4400455
45518706	45518728	22	-	27760321	OCIAML2	viability	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	0.11353937119047991	[654,580]	[457,647]	1	hSpCas9	negative selection	4483914
45518759	45518781	22	-	27760321	OCIAML2	viability	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.18992699208885358	[392,312]	[271,391]	2	hSpCas9	negative selection	4483915
45525638	45525660	22	-	27760321	OCIAML2	viability	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.3015962079291429	[915,693]	[790,802]	4	hSpCas9	negative selection	4483916
45527974	45527996	22	+	27760321	OCIAML2	viability	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.16229375231608179	[881,717]	[666,790]	2	hSpCas9	negative selection	4483917
45531300	45531322	22	-	27760321	OCIAML2	viability	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.2970390306395743	[314,243]	[198,376]	4	hSpCas9	negative selection	4483918
45518706	45518728	22	-	27760321	MV411	viability	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	0.3599143432920195	[654,580]	[667,303]	2	hSpCas9	negative selection	4567377
45518759	45518781	22	-	27760321	MV411	viability	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.6727085418576968	[392,312]	[482,197]	5	hSpCas9	negative selection	4567378
45525638	45525660	22	-	27760321	MV411	viability	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.0005716330759684141	[915,693]	[238,959]	0	hSpCas9	negative selection	4567379
45527974	45527996	22	+	27760321	MV411	viability	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	-0.5365483577250751	[881,717]	[230,558]	-4	hSpCas9	negative selection	4567380
45531300	45531322	22	-	27760321	MV411	viability	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	1.305228953443975	[314,243]	[625,191]	8	hSpCas9	negative selection	4567381
45518706	45518728	22	-	27760321	HL60	viability	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.36259043775778577	[654,580]	[391,391]	-4	hSpCas9	negative selection	4650840
45518759	45518781	22	-	27760321	HL60	viability	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.34332640043690194	[392,312]	[367,358]	4	hSpCas9	negative selection	4650841
45525638	45525660	22	-	27760321	HL60	viability	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.1525058079172651	[915,693]	[808,635]	1	hSpCas9	negative selection	4650842
45527974	45527996	22	+	27760321	HL60	viability	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.2626327949031636	[881,717]	[728,833]	3	hSpCas9	negative selection	4650843
45531300	45531322	22	-	27760321	HL60	viability	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.6323704189145198	[314,243]	[297,407]	7	hSpCas9	negative selection	4650844
45518706	45518728	22	-	27760321	HT1080	viability	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	0.03888562556668251	[580,453]	[154,273]	0	hSpCas9	negative selection	4734303
45518759	45518781	22	-	27760321	HT1080	viability	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	1.9726108015212382	[312,243]	[443,425]	9	hSpCas9	negative selection	4734304
45525638	45525660	22	-	27760321	HT1080	viability	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	-0.11784318303166808	[693,541]	[192,263]	0	hSpCas9	negative selection	4734305
45527974	45527996	22	+	27760321	HT1080	viability	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.7115774300336632	[717,559]	[244,604]	4	hSpCas9	negative selection	4734306
45531300	45531322	22	-	27760321	HT1080	viability	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	1.0410374222554357	[243,190]	[279,66]	5	hSpCas9	negative selection	4734307
45518706	45518728	22	-	27760321	HT29	viability after 7 days	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.15313154728695538	[580,453]	[788,449,582]	-2	hSpCas9	negative selection	4817766
45518759	45518781	22	-	27760321	HT29	viability after 7 days	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.3119160321325216	[312,243]	[374,603,346]	5	hSpCas9	negative selection	4817767
45525638	45525660	22	-	27760321	HT29	viability after 7 days	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.18111279059482333	[693,541]	[1198,711,834]	2	hSpCas9	negative selection	4817768
45527974	45527996	22	+	27760321	HT29	viability after 7 days	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.32649875870210665	[717,559]	[1211,1000,905]	5	hSpCas9	negative selection	4817769
45531300	45531322	22	-	27760321	HT29	viability after 7 days	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.2753810456095822	[243,190]	[393,195,429]	4	hSpCas9	negative selection	4817770
45518706	45518728	22	-	27760321	HT29	viability after 25 days	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.005140899741946425	[580,453]	[473,619,690]	0	hSpCas9	negative selection	4901229
45518759	45518781	22	-	27760321	HT29	viability after 25 days	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.21261763022465296	[312,243]	[406,399,287]	2	hSpCas9	negative selection	4901230
45525638	45525660	22	-	27760321	HT29	viability after 25 days	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.6245310119339373	[693,541]	[707,1009,1626]	7	hSpCas9	negative selection	4901231
45527974	45527996	22	+	27760321	HT29	viability after 25 days	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.34248829203132036	[717,559]	[1043,900,811]	3	hSpCas9	negative selection	4901232
45531300	45531322	22	-	27760321	HT29	viability after 25 days	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.6781575425738996	[243,190]	[350,573,255]	7	hSpCas9	negative selection	4901233
45518706	45518728	22	-	27760321	HT29	viability after 22 days	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	0.2781517914045737	[580,453]	[643,677,857]	3	hSpCas9	negative selection	4984692
45518759	45518781	22	-	27760321	HT29	viability after 22 days	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.4811582959188552	[312,243]	[610,361,369]	5	hSpCas9	negative selection	4984693
45525638	45525660	22	-	27760321	HT29	viability after 22 days	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.4880065859384244	[693,541]	[748,836,1430]	5	hSpCas9	negative selection	4984694
45527974	45527996	22	+	27760321	HT29	viability after 22 days	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.41451710638879735	[717,559]	[1329,660,952]	4	hSpCas9	negative selection	4984695
45531300	45531322	22	-	27760321	HT29	viability after 22 days	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	1.2428296151634513	[243,190]	[620,756,404]	9	hSpCas9	negative selection	4984696
45518706	45518728	22	-	27760321	HT29	viability after 19 days	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.347007352496135	[580,453]	[517,383,497]	-3	hSpCas9	negative selection	5068155
45518759	45518781	22	-	27760321	HT29	viability after 19 days	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.17645301769769212	[312,243]	[721,130,267]	1	hSpCas9	negative selection	5068156
45525638	45525660	22	-	27760321	HT29	viability after 19 days	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.24650110558653893	[693,541]	[759,967,780]	2	hSpCas9	negative selection	5068157
45527974	45527996	22	+	27760321	HT29	viability after 19 days	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.04809279553003587	[717,559]	[1219,586,516]	0	hSpCas9	negative selection	5068158
45531300	45531322	22	-	27760321	HT29	viability after 19 days	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	1.4045983545576475	[243,190]	[333,718,879]	9	hSpCas9	negative selection	5068159
45518706	45518728	22	-	27760321	HT29	viability after 16 days	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.03776013851418458	[580,453]	[667,522,511]	0	hSpCas9	negative selection	5151618
45518759	45518781	22	-	27760321	HT29	viability after 16 days	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	-0.2062317925823957	[312,243]	[352,345,116]	-2	hSpCas9	negative selection	5151619
45525638	45525660	22	-	27760321	HT29	viability after 16 days	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.763927361521523	[693,541]	[1352,950,1240]	8	hSpCas9	negative selection	5151620
45527974	45527996	22	+	27760321	HT29	viability after 16 days	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.23993738518848096	[717,559]	[1129,559,876]	2	hSpCas9	negative selection	5151621
45531300	45531322	22	-	27760321	HT29	viability after 16 days	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.76432388937267	[243,190]	[326,527,373]	8	hSpCas9	negative selection	5151622
45518706	45518728	22	-	27760321	HT29	viability after 13 days	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.02806799081550837	[580,453]	[688,570,510]	0	hSpCas9	negative selection	5235081
45518759	45518781	22	-	27760321	HT29	viability after 13 days	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.4266888411633245	[312,243]	[676,478,162]	5	hSpCas9	negative selection	5235082
45525638	45525660	22	-	27760321	HT29	viability after 13 days	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.5071182613736447	[693,541]	[698,1552,817]	6	hSpCas9	negative selection	5235083
45527974	45527996	22	+	27760321	HT29	viability after 13 days	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.1425758131824012	[717,559]	[560,968,918]	1	hSpCas9	negative selection	5235084
45531300	45531322	22	-	27760321	HT29	viability after 13 days	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.7292922761912686	[243,190]	[530,444,286]	8	hSpCas9	negative selection	5235085
45518706	45518728	22	-	27760321	HT29	viability after 10 days	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	-0.3008991819468829	[580,453]	[573,371,620]	-4	hSpCas9	negative selection	5318544
45518759	45518781	22	-	27760321	HT29	viability after 10 days	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.34923634165054857	[312,243]	[381,455,489]	5	hSpCas9	negative selection	5318545
45525638	45525660	22	-	27760321	HT29	viability after 10 days	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.4349782870870802	[693,541]	[1024,1284,830]	6	hSpCas9	negative selection	5318546
45527974	45527996	22	+	27760321	HT29	viability after 10 days	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.23186101529927372	[717,559]	[978,987,846]	3	hSpCas9	negative selection	5318547
45531300	45531322	22	-	27760321	HT29	viability after 10 days	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	0.815350749977051	[243,190]	[287,606,540]	9	hSpCas9	negative selection	5318548
45518706	45518728	22	-	27760321	MOLM13	viability	CGGTGTCCGTCCGCACAGCAGG	FBLN1	ENSG00000077942	0.6483806849150744	[654,580]	[274,775]	4	hSpCas9	negative selection	5402007
45518759	45518781	22	-	27760321	MOLM13	viability	CTTTGGATTCCGTAGCATATGG	FBLN1	ENSG00000077942	0.6417254235500441	[392,312]	[377,249]	4	hSpCas9	negative selection	5402008
45525638	45525660	22	-	27760321	MOLM13	viability	AGGCTGGCGTTGTCACCGTGGG	FBLN1	ENSG00000077942	0.8260802428281794	[915,693]	[1057,577]	6	hSpCas9	negative selection	5402009
45527974	45527996	22	+	27760321	MOLM13	viability	CCGGAGATTTGGATGTCGGGGG	FBLN1	ENSG00000077942	0.8956945691672326	[881,717]	[694,954]	6	hSpCas9	negative selection	5402010
45531300	45531322	22	-	27760321	MOLM13	viability	GGCAGCGGTCATTCAGATATGG	FBLN1	ENSG00000077942	2.3062125439537473	[314,243]	[1347,285]	9	hSpCas9	negative selection	5402011
45503048	45503071	22	+	27661255	K562	viability	GCTGCTGGCGGCCGGAGGTAGGG	FBLN1	ENSG00000077942	-0.8051182866897233	[211,163]	[101,72]	-8	dCas9-KRAB	negative selection	5479586
45502941	45502964	22	-	27661255	K562	viability	GGCGGCGGCGGACAAAGGCGCGG	FBLN1	ENSG00000077942	-0.12967216023281547	[317,302]	[234,219]	-4	dCas9-KRAB	negative selection	5479587
45503088	45503111	22	-	27661255	K562	viability	GGGGTCGGGACCCTAAGCTGGGG	FBLN1	ENSG00000077942	-3.360573760219495	[260,227]	[24,13]	-9	dCas9-KRAB	negative selection	5479588
45503292	45503315	22	-	27661255	K562	viability	GGTAGGACGGTGTGTTTGAGGGG	FBLN1	ENSG00000077942	0.1138672701303598	[1226,993]	[1131,819]	4	dCas9-KRAB	negative selection	5479589
45503313	45503336	22	-	27661255	K562	viability	GGCTGGATTTGCTAGGACTGGGG	FBLN1	ENSG00000077942	0.14068404510830773	[1042,1090]	[1021,867]	5	dCas9-KRAB	negative selection	5479590
45541341	45541364	22	-	27260156	BXPC3	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.3658372880605146	[318]	[362,356,502,516]	7	hSpCas9	negative selection	5543092
45541264	45541287	22	-	27260156	BXPC3	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.023689223015338656	[528]	[405,567,616,603]	0	hSpCas9	negative selection	5543093
45527987	45528010	22	+	27260156	BXPC3	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.03697157989904576	[121]	[101,140,105,151]	-1	hSpCas9	negative selection	5543094
45527966	45527989	22	-	27260156	BXPC3	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.36318767751073766	[734]	[877,981,1002,1111]	7	hSpCas9	negative selection	5607356
45525611	45525634	22	-	27260156	BXPC3	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.4682883171357952	[313]	[168,321,193,267]	-7	hSpCas9	negative selection	5607357
45525639	45525662	22	-	27260156	BXPC3	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.4216045463056979	[50]	[76,86,32,87]	8	hSpCas9	negative selection	5607358
45541341	45541364	22	-	27260156	A673	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.45299695389561917	[318]	[495,572,453,571]	8	hSpCas9	negative selection	5664343
45541264	45541287	22	-	27260156	A673	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.01388572569078833	[528]	[665,598,643,659]	0	hSpCas9	negative selection	5664344
45527987	45528010	22	+	27260156	A673	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.02484983335576585	[121]	[178,107,152,160]	0	hSpCas9	negative selection	5664345
45527966	45527989	22	-	27260156	A673	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.26715646925963166	[734]	[1201,951,1082,1025]	6	hSpCas9	negative selection	5728607
45525611	45525634	22	-	27260156	A673	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	0.06208070111889619	[313]	[354,487,363,357]	1	hSpCas9	negative selection	5728608
45525639	45525662	22	-	27260156	A673	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5560113530675164	[50]	[65,96,130,60]	9	hSpCas9	negative selection	5728609
45541341	45541364	22	-	27260156	A375	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.33539991160763866	[318]	[406,649,420,429]	5	hSpCas9	negative selection	5785594
45541264	45541287	22	-	27260156	A375	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.2229987992111309	[528]	[951,767,559,621]	3	hSpCas9	negative selection	5785595
45527987	45528010	22	+	27260156	A375	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.266815256189177	[121]	[67,225,143,244]	4	hSpCas9	negative selection	5785596
45527966	45527989	22	-	27260156	A375	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.5346827009467237	[734]	[943,1385,1642,1038]	7	hSpCas9	negative selection	5849858
45525611	45525634	22	-	27260156	A375	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.5502190644688663	[313]	[343,180,235,232]	-6	hSpCas9	negative selection	5849859
45525639	45525662	22	-	27260156	A375	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.7798825444764379	[50]	[49,51,156,137]	9	hSpCas9	negative selection	5849860
45541341	45541364	22	-	27260156	COLO741	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.1816005213334645	[318]	[393,337,348]	-4	hSpCas9	negative selection	5906845
45541264	45541287	22	-	27260156	COLO741	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.06668159695205006	[528]	[931,603,611]	1	hSpCas9	negative selection	5906846
45527987	45528010	22	+	27260156	COLO741	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.09299646407051987	[121]	[253,117,135]	2	hSpCas9	negative selection	5906847
45527966	45527989	22	-	27260156	COLO741	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.26371411475878914	[734]	[1372,1147,896]	5	hSpCas9	negative selection	5971109
45525611	45525634	22	-	27260156	COLO741	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.44285020674909936	[313]	[282,405,201]	-7	hSpCas9	negative selection	5971110
45525639	45525662	22	-	27260156	COLO741	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.8121355885563353	[50]	[164,148,38]	9	hSpCas9	negative selection	5971111
45541341	45541364	22	-	27260156	CAL120	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.16343389921725093	[318]	[296,260,493]	-2	hSpCas9	negative selection	6028096
45541264	45541287	22	-	27260156	CAL120	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.09964911617392905	[528]	[714,795,607]	1	hSpCas9	negative selection	6028097
45527987	45528010	22	+	27260156	CAL120	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.2718998302573312	[121]	[178,64,302]	4	hSpCas9	negative selection	6028098
45527966	45527989	22	-	27260156	CAL120	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.6446851067130013	[734]	[1587,1017,1701]	8	hSpCas9	negative selection	6092360
45525611	45525634	22	-	27260156	CAL120	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.42897056504885334	[313]	[167,326,355]	-6	hSpCas9	negative selection	6092361
45525639	45525662	22	-	27260156	CAL120	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	-0.5264341059722377	[50]	[30,43,54]	-6	hSpCas9	negative selection	6092362
45541341	45541364	22	-	27260156	CADOES1	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.41049468519651955	[318]	[439,418,331,385]	6	hSpCas9	negative selection	6149347
45541264	45541287	22	-	27260156	CADOES1	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.09390765389702252	[528]	[639,557,406,493]	1	hSpCas9	negative selection	6149348
45527987	45528010	22	+	27260156	CADOES1	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.3445129770577704	[121]	[178,161,71,163]	6	hSpCas9	negative selection	6149349
45527966	45527989	22	-	27260156	CADOES1	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.6176479540141346	[734]	[1021,1202,920,1049]	8	hSpCas9	negative selection	6213611
45525611	45525634	22	-	27260156	CADOES1	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.36497419442822465	[313]	[261,163,325,151]	-6	hSpCas9	negative selection	6213612
45525639	45525662	22	-	27260156	CADOES1	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	-0.0915569589658749	[50]	[43,56,34,41]	-1	hSpCas9	negative selection	6213613
45541341	45541364	22	-	27260156	EWS502	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.2584673402026322	[318]	[376,359,371,518]	4	hSpCas9	negative selection	6270598
45541264	45541287	22	-	27260156	EWS502	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.4027886003390301	[528]	[731,756,672,801]	7	hSpCas9	negative selection	6270599
45527987	45528010	22	+	27260156	EWS502	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.23207147083941315	[121]	[100,96,78,167]	-4	hSpCas9	negative selection	6270600
45527966	45527989	22	-	27260156	EWS502	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.5442758088478041	[734]	[1260,1053,942,1273]	8	hSpCas9	negative selection	6334862
45525611	45525634	22	-	27260156	EWS502	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.239712013433923	[313]	[329,260,328,194]	-4	hSpCas9	negative selection	6334863
45525639	45525662	22	-	27260156	EWS502	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.7191214310831842	[50]	[139,74,62,69]	9	hSpCas9	negative selection	6334864
45541341	45541364	22	-	27260156	EW8	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.0004783427513266325	[318]	[180,259,325,245]	0	hSpCas9	negative selection	6391849
45541264	45541287	22	-	27260156	EW8	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.06782360033754502	[528]	[413,349,480,377]	-1	hSpCas9	negative selection	6391850
45527987	45528010	22	+	27260156	EW8	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.18105104488449175	[121]	[194,58,75,132]	3	hSpCas9	negative selection	6391851
45527966	45527989	22	-	27260156	EW8	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.32844779915193756	[734]	[911,692,691,719]	6	hSpCas9	negative selection	6456113
45525611	45525634	22	-	27260156	EW8	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.4672864062653015	[313]	[192,109,196,233]	-7	hSpCas9	negative selection	6456114
45525639	45525662	22	-	27260156	EW8	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.223330245662976	[50]	[49,34,47,59]	4	hSpCas9	negative selection	6456115
45541341	45541364	22	-	27260156	CORL105	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.31385204860769456	[318]	[454,312,478,613]	6	hSpCas9	negative selection	6513100
45541264	45541287	22	-	27260156	CORL105	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.3328116364749507	[528]	[796,554,1018,790]	6	hSpCas9	negative selection	6513101
45527987	45528010	22	+	27260156	CORL105	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.0360919455860198	[121]	[164,104,153,136]	0	hSpCas9	negative selection	6513102
45527966	45527989	22	-	27260156	CORL105	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.4092750753664989	[734]	[1328,1200,1244,817]	7	hSpCas9	negative selection	6577364
45525611	45525634	22	-	27260156	CORL105	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.4311118885500025	[313]	[254,290,331,220]	-7	hSpCas9	negative selection	6577365
45525639	45525662	22	-	27260156	CORL105	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.354145410114199	[50]	[72,74,87,70]	6	hSpCas9	negative selection	6577366
45541341	45541364	22	-	27260156	HS294T	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.32895451143508614	[318]	[86,107,105,90]	-5	hSpCas9	negative selection	6634351
45541264	45541287	22	-	27260156	HS294T	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.19207807965677223	[528]	[199,239,192,317]	2	hSpCas9	negative selection	6634352
45527987	45528010	22	+	27260156	HS294T	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.49941068301650793	[121]	[34,22,34,41]	-6	hSpCas9	negative selection	6634353
45527966	45527989	22	-	27260156	HS294T	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.4362105143857171	[734]	[405,343,366,425]	6	hSpCas9	negative selection	6698615
45525611	45525634	22	-	27260156	HS294T	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.4034100561966727	[313]	[71,81,103,114]	-5	hSpCas9	negative selection	6698616
45525639	45525662	22	-	27260156	HS294T	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	1.6262040347481888	[50]	[28,43,32,156]	9	hSpCas9	negative selection	6698617
45541341	45541364	22	-	27260156	HCC44	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.4107484477613046	[318]	[464,368,551,552]	6	hSpCas9	negative selection	6755602
45541264	45541287	22	-	27260156	HCC44	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.03604609356669386	[528]	[655,542,565,573]	0	hSpCas9	negative selection	6755603
45527987	45528010	22	+	27260156	HCC44	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.3261882989107976	[121]	[141,104,182,265]	5	hSpCas9	negative selection	6755604
45527966	45527989	22	-	27260156	HCC44	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.47240901495041143	[734]	[1498,945,1364,899]	7	hSpCas9	negative selection	6819866
45525611	45525634	22	-	27260156	HCC44	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.29218683340559526	[313]	[262,221,431,272]	-5	hSpCas9	negative selection	6819867
45525639	45525662	22	-	27260156	HCC44	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.3646002341251289	[50]	[148,32,84,44]	6	hSpCas9	negative selection	6819868
45541341	45541364	22	-	27260156	G402	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.06969169715603363	[318]	[419,340,477,391]	0	hSpCas9	negative selection	6876853
45541264	45541287	22	-	27260156	G402	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.15403399191997172	[528]	[564,706,631,426]	-2	hSpCas9	negative selection	6876854
45527987	45528010	22	+	27260156	G402	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.02023479927605143	[121]	[124,135,305,21]	0	hSpCas9	negative selection	6876855
45527966	45527989	22	-	27260156	G402	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.4446877284187156	[734]	[1366,1379,1148,1021]	5	hSpCas9	negative selection	6941117
45525611	45525634	22	-	27260156	G402	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.45269392955234067	[313]	[214,358,345,197]	-5	hSpCas9	negative selection	6941118
45525639	45525662	22	-	27260156	G402	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.42550257078105735	[50]	[85,69,39,134]	5	hSpCas9	negative selection	6941119
45541341	45541364	22	-	27260156	L33	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.2910887493160004	[318]	[362,174,216,425]	6	hSpCas9	negative selection	6998104
45541264	45541287	22	-	27260156	L33	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.21765173323122003	[528]	[545,256,433,598]	5	hSpCas9	negative selection	6998105
45527987	45528010	22	+	27260156	L33	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.34549273018944615	[121]	[173,50,120,128]	7	hSpCas9	negative selection	6998106
45527966	45527989	22	-	27260156	L33	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.350070484170133	[734]	[864,360,642,979]	7	hSpCas9	negative selection	7062368
45525611	45525634	22	-	27260156	L33	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.09549574514687653	[313]	[250,120,243,242]	-2	hSpCas9	negative selection	7062369
45525639	45525662	22	-	27260156	L33	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.21725170979185293	[50]	[46,36,28,53]	5	hSpCas9	negative selection	7062370
45541341	45541364	22	-	27260156	K562	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.12216711071665709	[318]	[228,279,281,418]	1	hSpCas9	negative selection	7119355
45541264	45541287	22	-	27260156	K562	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.21327446679033799	[528]	[742,493,479,478]	2	hSpCas9	negative selection	7119356
45527987	45528010	22	+	27260156	K562	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.12677782956361816	[121]	[160,91,13,197]	1	hSpCas9	negative selection	7119357
45527966	45527989	22	-	27260156	K562	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.6040229070878183	[734]	[1469,947,991,630]	7	hSpCas9	negative selection	7183619
45525611	45525634	22	-	27260156	K562	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	0.3170278685628809	[313]	[310,278,579,224]	4	hSpCas9	negative selection	7183620
45525639	45525662	22	-	27260156	K562	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	1.2044382422633315	[50]	[115,128,97,78]	9	hSpCas9	negative selection	7183621
45541341	45541364	22	-	27260156	HT29	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.5208524704559999	[318]	[657,852,413,354]	8	hSpCas9	negative selection	7240606
45541264	45541287	22	-	27260156	HT29	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.03018263048443212	[528]	[720,649,601,558]	0	hSpCas9	negative selection	7240607
45527987	45528010	22	+	27260156	HT29	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.3250080948054581	[121]	[165,174,146,243]	6	hSpCas9	negative selection	7240608
45527966	45527989	22	-	27260156	HT29	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.5494484950290566	[734]	[1685,1378,1294,941]	9	hSpCas9	negative selection	7304870
45525611	45525634	22	-	27260156	HT29	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.5699107485255686	[313]	[304,272,261,198]	-7	hSpCas9	negative selection	7304871
45525639	45525662	22	-	27260156	HT29	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5921301761358029	[50]	[89,102,71,106]	9	hSpCas9	negative selection	7304872
45541341	45541364	22	-	27260156	MHHES1	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.22393253106698752	[318]	[509,226,576,360]	4	hSpCas9	negative selection	7361857
45541264	45541287	22	-	27260156	MHHES1	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.2261326939051385	[528]	[1000,509,856,474]	4	hSpCas9	negative selection	7361858
45527987	45528010	22	+	27260156	MHHES1	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.6016517262606014	[121]	[49,66,159,78]	-8	hSpCas9	negative selection	7361859
45527966	45527989	22	-	27260156	MHHES1	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.22281170185334542	[734]	[699,1416,993,786]	4	hSpCas9	negative selection	7426121
45525611	45525634	22	-	27260156	MHHES1	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.40443336830121135	[313]	[524,127,295,156]	-6	hSpCas9	negative selection	7426122
45525639	45525662	22	-	27260156	MHHES1	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.8303867085804701	[50]	[60,154,171,34]	9	hSpCas9	negative selection	7426123
45541341	45541364	22	-	27260156	MEWO	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.44133470215235787	[318]	[425,336,456]	8	hSpCas9	negative selection	7483108
45541264	45541287	22	-	27260156	MEWO	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.17420084667241156	[528]	[517,625,522]	4	hSpCas9	negative selection	7483109
45527987	45528010	22	+	27260156	MEWO	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.027750359723578866	[121]	[120,103,124]	0	hSpCas9	negative selection	7483110
45527966	45527989	22	-	27260156	MEWO	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.1703017048122022	[734]	[947,765,640]	4	hSpCas9	negative selection	7547372
45525611	45525634	22	-	27260156	MEWO	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.4120125470679361	[313]	[274,182,214]	-7	hSpCas9	negative selection	7547373
45525639	45525662	22	-	27260156	MEWO	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.6492871091962433	[50]	[112,49,68]	9	hSpCas9	negative selection	7547374
45541341	45541364	22	-	27260156	LNCAPCLONEFGC	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.0020914814613753885	[318]	[295,300,348,215]	0	hSpCas9	negative selection	7604359
45541264	45541287	22	-	27260156	LNCAPCLONEFGC	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.22216322467855074	[528]	[532,631,678,404]	3	hSpCas9	negative selection	7604360
45527987	45528010	22	+	27260156	LNCAPCLONEFGC	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.5144928009376699	[121]	[78,214,183,154]	7	hSpCas9	negative selection	7604361
45527966	45527989	22	-	27260156	LNCAPCLONEFGC	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.49803940812731895	[734]	[868,898,921,1071]	7	hSpCas9	negative selection	7668623
45525611	45525634	22	-	27260156	LNCAPCLONEFGC	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.6475236053244058	[313]	[149,228,230,120]	-7	hSpCas9	negative selection	7668624
45525639	45525662	22	-	27260156	LNCAPCLONEFGC	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.6878434529165958	[50]	[47,49,102,102]	9	hSpCas9	negative selection	7668625
45541341	45541364	22	-	27260156	PANC0327	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.39916542117765674	[318]	[253,588,314,298]	6	hSpCas9	negative selection	7725610
45541264	45541287	22	-	27260156	PANC0327	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.21168987187121954	[528]	[747,406,540,514]	3	hSpCas9	negative selection	7725611
45527987	45528010	22	+	27260156	PANC0327	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.35538494712919033	[121]	[137,140,60,213]	5	hSpCas9	negative selection	7725612
45527966	45527989	22	-	27260156	PANC0327	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.29759268068010103	[734]	[953,895,717,641]	4	hSpCas9	negative selection	7789874
45525611	45525634	22	-	27260156	PANC0327	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	0.19834465045613997	[313]	[200,198,423,461]	3	hSpCas9	negative selection	7789875
45525639	45525662	22	-	27260156	PANC0327	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5948994357845367	[50]	[26,77,55,107]	8	hSpCas9	negative selection	7789876
45541341	45541364	22	-	27260156	NCIH2009	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.5949585251731879	[318]	[659,717,636]	7	hSpCas9	negative selection	7846861
45541264	45541287	22	-	27260156	NCIH2009	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.1207051473780981	[528]	[877,534,1015]	1	hSpCas9	negative selection	7846862
45527987	45528010	22	+	27260156	NCIH2009	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.3888971707866056	[121]	[149,207,296]	5	hSpCas9	negative selection	7846863
45527966	45527989	22	-	27260156	NCIH2009	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.8579674067368441	[734]	[2137,1602,1898]	9	hSpCas9	negative selection	7911125
45525611	45525634	22	-	27260156	NCIH2009	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.019505762450179542	[313]	[517,407,388]	0	hSpCas9	negative selection	7911126
45525639	45525662	22	-	27260156	NCIH2009	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	1.0532808710713937	[50]	[125,94,218]	9	hSpCas9	negative selection	7911127
45541341	45541364	22	-	27260156	NCIH1373	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.06535517407795799	[318]	[665,271,214,105]	0	hSpCas9	negative selection	7968112
45541264	45541287	22	-	27260156	NCIH1373	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.4993503985624591	[528]	[1556,429,648,229]	5	hSpCas9	negative selection	7968113
45527987	45528010	22	+	27260156	NCIH1373	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.14922703895277745	[121]	[125,106,247,31]	1	hSpCas9	negative selection	7968114
45527966	45527989	22	-	27260156	NCIH1373	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	1.1594277517425078	[734]	[2539,1530,1694,452]	9	hSpCas9	negative selection	8032376
45525611	45525634	22	-	27260156	NCIH1373	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.8964620409554154	[313]	[112,233,165,59]	-7	hSpCas9	negative selection	8032377
45525639	45525662	22	-	27260156	NCIH1373	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.17615789204835863	[50]	[155,37,34,11]	1	hSpCas9	negative selection	8032378
45541341	45541364	22	-	27260156	PATU8902	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.8983319504267123	[318]	[710,977,571,1151]	8	hSpCas9	negative selection	8089363
45541264	45541287	22	-	27260156	PATU8902	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.016523687017271027	[528]	[938,534,537,1049]	0	hSpCas9	negative selection	8089364
45527987	45528010	22	+	27260156	PATU8902	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.0368728116466821	[121]	[150,182,111,237]	0	hSpCas9	negative selection	8089365
45527966	45527989	22	-	27260156	PATU8902	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.7380510861486158	[734]	[2223,1817,874,2162]	7	hSpCas9	negative selection	8153627
45525611	45525634	22	-	27260156	PATU8902	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.19077251171666387	[313]	[420,376,408,305]	-2	hSpCas9	negative selection	8153628
45525639	45525662	22	-	27260156	PATU8902	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	-0.4567872648352025	[50]	[33,46,4,143]	-4	hSpCas9	negative selection	8153629
45541341	45541364	22	-	27260156	PANC1	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.7192966968877924	[318]	[401,445,595,367]	9	hSpCas9	negative selection	8210614
45541264	45541287	22	-	27260156	PANC1	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.1415299590187776	[528]	[520,678,395,444]	2	hSpCas9	negative selection	8210615
45527987	45528010	22	+	27260156	PANC1	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.006969489510011417	[121]	[104,86,188,41]	0	hSpCas9	negative selection	8210616
45527966	45527989	22	-	27260156	PANC1	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.49663840215847643	[734]	[806,1251,889,705]	7	hSpCas9	negative selection	8274878
45525611	45525634	22	-	27260156	PANC1	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.7137093823226821	[313]	[193,222,171,89]	-7	hSpCas9	negative selection	8274879
45525639	45525662	22	-	27260156	PANC1	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	1.089349087977833	[50]	[112,92,159,17]	9	hSpCas9	negative selection	8274880
45541341	45541364	22	-	27260156	PANC0813	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.0920032305389189	[318]	[354,439,267,342]	-1	hSpCas9	negative selection	8331865
45541264	45541287	22	-	27260156	PANC0813	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.28324764715277984	[528]	[830,791,635,769]	4	hSpCas9	negative selection	8331866
45527987	45528010	22	+	27260156	PANC0813	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.13987740753720335	[121]	[194,105,160,171]	2	hSpCas9	negative selection	8331867
45527966	45527989	22	-	27260156	PANC0813	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.39225084384495923	[734]	[1214,1014,1116,1187]	6	hSpCas9	negative selection	8396129
45525611	45525634	22	-	27260156	PANC0813	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	0.5086902245124207	[313]	[421,403,913,359]	7	hSpCas9	negative selection	8396130
45525639	45525662	22	-	27260156	PANC0813	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	-0.029795659484125547	[50]	[43,80,62,45]	0	hSpCas9	negative selection	8396131
45541341	45541364	22	-	27260156	RDES	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.18554449783612037	[318]	[305,385,464,548]	3	hSpCas9	negative selection	8453116
45541264	45541287	22	-	27260156	RDES	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.30181676546983605	[528]	[576,810,765,873]	5	hSpCas9	negative selection	8453117
45527987	45528010	22	+	27260156	RDES	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	-0.09981612276614316	[121]	[75,118,147,201]	-2	hSpCas9	negative selection	8453118
45527966	45527989	22	-	27260156	RDES	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.4756922307080811	[734]	[1043,1105,1364,1193]	7	hSpCas9	negative selection	8517380
45525611	45525634	22	-	27260156	RDES	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.9974649768809833	[313]	[167,193,165,191]	-9	hSpCas9	negative selection	8517381
45525639	45525662	22	-	27260156	RDES	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.4515735614101053	[50]	[51,81,116,73]	7	hSpCas9	negative selection	8517382
45541341	45541364	22	-	27260156	PC3	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.25285877907423115	[318]	[273,286,641,426]	5	hSpCas9	negative selection	8574367
45541264	45541287	22	-	27260156	PC3	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.07609260408778191	[528]	[316,348,1090,515]	-2	hSpCas9	negative selection	8574368
45527987	45528010	22	+	27260156	PC3	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.3337883539303108	[121]	[106,110,252,188]	7	hSpCas9	negative selection	8574369
45527966	45527989	22	-	27260156	PC3	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.2262182201413634	[734]	[424,1047,1371,893]	5	hSpCas9	negative selection	8638631
45525611	45525634	22	-	27260156	PC3	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.06800932585861375	[313]	[109,356,223,544]	-1	hSpCas9	negative selection	8638632
45525639	45525662	22	-	27260156	PC3	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.2204496439971142	[50]	[27,77,92,58]	5	hSpCas9	negative selection	8638633
45541341	45541364	22	-	27260156	PATU8988T	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.7605621623267004	[318]	[447,527,632,474]	9	hSpCas9	negative selection	8695618
45541264	45541287	22	-	27260156	PATU8988T	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.07461717822320811	[528]	[483,662,389,416]	-1	hSpCas9	negative selection	8695619
45527987	45528010	22	+	27260156	PATU8988T	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.053731044784500526	[121]	[81,88,204,107]	0	hSpCas9	negative selection	8695620
45527966	45527989	22	-	27260156	PATU8988T	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.4739818637386355	[734]	[1151,933,609,1272]	7	hSpCas9	negative selection	8759882
45525611	45525634	22	-	27260156	PATU8988T	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.5151741964506071	[313]	[203,304,116,234]	-7	hSpCas9	negative selection	8759883
45525639	45525662	22	-	27260156	PATU8988T	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5444131907803729	[50]	[19,67,41,164]	8	hSpCas9	negative selection	8759884
45541341	45541364	22	-	27260156	T47D	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.31894226288729666	[318]	[438,495,480,433]	6	hSpCas9	negative selection	8816869
45541264	45541287	22	-	27260156	T47D	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.11029081149616435	[528]	[685,634,661,680]	2	hSpCas9	negative selection	8816870
45527987	45528010	22	+	27260156	T47D	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.23512518143573313	[121]	[202,132,172,162]	5	hSpCas9	negative selection	8816871
45527966	45527989	22	-	27260156	T47D	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.20896290356438507	[734]	[964,995,998,997]	4	hSpCas9	negative selection	8881133
45525611	45525634	22	-	27260156	T47D	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.3380985875469591	[313]	[273,270,291,322]	-6	hSpCas9	negative selection	8881134
45525639	45525662	22	-	27260156	T47D	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.7169297388528735	[50]	[113,80,80,116]	9	hSpCas9	negative selection	8881135
45541341	45541364	22	-	27260156	SU8686	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.2769569682181341	[318]	[372,277,367,552]	5	hSpCas9	negative selection	8938120
45541264	45541287	22	-	27260156	SU8686	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	0.23415078153397276	[528]	[535,563,630,773]	4	hSpCas9	negative selection	8938121
45527987	45528010	22	+	27260156	SU8686	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.5615653409166605	[121]	[129,193,178,219]	8	hSpCas9	negative selection	8938122
45527966	45527989	22	-	27260156	SU8686	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.527124581135411	[734]	[1122,859,1070,1175]	8	hSpCas9	negative selection	9002384
45525611	45525634	22	-	27260156	SU8686	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.35629523312628897	[313]	[225,215,222,323]	-5	hSpCas9	negative selection	9002385
45525639	45525662	22	-	27260156	SU8686	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	1.0846954629790595	[50]	[95,134,100,90]	9	hSpCas9	negative selection	9002386
45541341	45541364	22	-	27260156	SKES1	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	-0.0018147932624487106	[318]	[259,401,390,226]	0	hSpCas9	negative selection	9059371
45541264	45541287	22	-	27260156	SKES1	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.016056213439486877	[528]	[534,738,445,404]	0	hSpCas9	negative selection	9059372
45527987	45528010	22	+	27260156	SKES1	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.44498588650871906	[121]	[132,236,93,197]	8	hSpCas9	negative selection	9059373
45527966	45527989	22	-	27260156	SKES1	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.284181324809606	[734]	[1020,1114,732,755]	6	hSpCas9	negative selection	9123635
45525611	45525634	22	-	27260156	SKES1	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.5246499960544226	[313]	[218,154,283,203]	-8	hSpCas9	negative selection	9123636
45525639	45525662	22	-	27260156	SKES1	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.5842855656989792	[50]	[54,155,48,53]	9	hSpCas9	negative selection	9123637
45541341	45541364	22	-	27260156	TOV112D	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.41138608095186624	[318]	[372,815,327,277]	7	hSpCas9	negative selection	9180622
45541264	45541287	22	-	27260156	TOV112D	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.010100404574283378	[528]	[592,658,292,594]	0	hSpCas9	negative selection	9180623
45527987	45528010	22	+	27260156	TOV112D	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.49368483877601066	[121]	[331,194,115,66]	8	hSpCas9	negative selection	9180624
45527966	45527989	22	-	27260156	TOV112D	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.16591693141695818	[734]	[1042,1018,737,574]	3	hSpCas9	negative selection	9244886
45525611	45525634	22	-	27260156	TOV112D	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.3002963678095212	[313]	[317,283,195,235]	-5	hSpCas9	negative selection	9244887
45525639	45525662	22	-	27260156	TOV112D	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.945436707444876	[50]	[159,88,41,104]	9	hSpCas9	negative selection	9244888
45541341	45541364	22	-	27260156	TC71	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.33504890970648504	[318]	[329,434,561,393]	7	hSpCas9	negative selection	9301873
45541264	45541287	22	-	27260156	TC71	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.11177475845029777	[528]	[550,555,461,531]	-3	hSpCas9	negative selection	9301874
45527987	45528010	22	+	27260156	TC71	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.5311182581162874	[121]	[188,208,154,204]	9	hSpCas9	negative selection	9301875
45527966	45527989	22	-	27260156	TC71	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.1620369281855989	[734]	[853,806,765,1117]	4	hSpCas9	negative selection	9366137
45525611	45525634	22	-	27260156	TC71	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.21295369768717676	[313]	[231,333,239,362]	-5	hSpCas9	negative selection	9366138
45525639	45525662	22	-	27260156	TC71	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.8362295696732409	[50]	[72,96,113,106]	9	hSpCas9	negative selection	9366139
45541341	45541364	22	-	27260156	TC32	viability	GCGTTCCCTCCTCGTTGAGATGG	FBLN1	ENSG00000077942	0.16821035513370142	[318]	[300,245,494,352]	3	hSpCas9	negative selection	9423124
45541264	45541287	22	-	27260156	TC32	viability	TTGATGCATGTATGCCCGATAGG	FBLN1	ENSG00000077942	-0.20731678867795464	[528]	[451,283,520,512]	-4	hSpCas9	negative selection	9423125
45527987	45528010	22	+	27260156	TC32	viability	TGTCGGGGGCCTCCAAGAAACGG	FBLN1	ENSG00000077942	0.5114232599043784	[121]	[158,192,102,165]	8	hSpCas9	negative selection	9423126
45527966	45527989	22	-	27260156	TC32	viability	CATCCAAATCTCCGGTCTCCTGG	FBLN1	ENSG00000077942	0.4793891526362337	[734]	[816,849,1163,1062]	7	hSpCas9	negative selection	9487388
45525611	45525634	22	-	27260156	TC32	viability	GGCACAGCGGTCCTGCTCGTTGG	FBLN1	ENSG00000077942	-0.16538450717206454	[313]	[219,248,345,244]	-3	hSpCas9	negative selection	9487389
45525639	45525662	22	-	27260156	TC32	viability	CCAGGCTGGCGTTGTCACCGTGG	FBLN1	ENSG00000077942	0.56848058113781	[50]	[85,38,72,93]	8	hSpCas9	negative selection	9487390
45518710	45518733	22	+	27869803	HPAFII	viability after 27 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.11829550521969995	[237]	[83,178,NaN]	0	hSpCas9	negative selection	9581350
45523130	45523153	22	+	27869803	HPAFII	viability after 27 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.34234005804723733	[707]	[622,345,NaN]	2	hSpCas9	negative selection	9581351
45525600	45525623	22	+	27869803	HPAFII	viability after 27 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.07151531805418243	[289]	[185,110,NaN]	0	hSpCas9	negative selection	9581352
45527948	45527971	22	+	27869803	HPAFII	viability after 27 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	-0.41415612159183923	[99]	[69,13,NaN]	-3	hSpCas9	negative selection	9581353
45531303	45531326	22	+	27869803	HPAFII	viability after 27 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.3461178220444152	[130]	[92,82,NaN]	2	hSpCas9	negative selection	9581354
45533088	45533111	22	+	27869803	HPAFII	viability after 27 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.5957053375690018	[429]	[267,402,NaN]	5	hSpCas9	negative selection	9581355
45518710	45518733	22	+	27869803	HPAFII	viability after 15 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.5205977040303316	[237]	[218,152,NaN]	-5	hSpCas9	negative selection	9663799
45523130	45523153	22	+	27869803	HPAFII	viability after 15 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.461106026985145	[707]	[1200,951,NaN]	5	hSpCas9	negative selection	9663800
45525600	45525623	22	+	27869803	HPAFII	viability after 15 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.08569433279685473	[289]	[445,198,NaN]	-1	hSpCas9	negative selection	9663801
45527948	45527971	22	+	27869803	HPAFII	viability after 15 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.10634408130463435	[99]	[230,43,NaN]	1	hSpCas9	negative selection	9663802
45531303	45531326	22	+	27869803	HPAFII	viability after 15 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.3160551440524165	[130]	[231,139,NaN]	3	hSpCas9	negative selection	9663803
45533088	45533111	22	+	27869803	HPAFII	viability after 15 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.7380859712477263	[429]	[1170,521,NaN]	8	hSpCas9	negative selection	9663804
45518710	45518733	22	+	27869803	ASPC1	viability after 36 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.2216003652410603	[451]	[89,47,234]	-2	hSpCas9	negative selection	9746248
45523130	45523153	22	+	27869803	ASPC1	viability after 36 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.32806217665041104	[1799]	[1086,812,551]	3	hSpCas9	negative selection	9746249
45525600	45525623	22	+	27869803	ASPC1	viability after 36 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	0.5395904104437629	[659]	[719,319,72]	5	hSpCas9	negative selection	9746250
45527948	45527971	22	+	27869803	ASPC1	viability after 36 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.18282577384301613	[141]	[9,97,54]	1	hSpCas9	negative selection	9746251
45531303	45531326	22	+	27869803	ASPC1	viability after 36 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.25602328769984295	[351]	[127,126,173]	2	hSpCas9	negative selection	9746252
45533088	45533111	22	+	27869803	ASPC1	viability after 36 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.24337836746877184	[1248]	[763,569,293]	2	hSpCas9	negative selection	9746253
45518710	45518733	22	+	27869803	PATU8988S	viability after 35 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.48433179085027445	[291]	[172,155,NaN]	5	hSpCas9	negative selection	9828697
45523130	45523153	22	+	27869803	PATU8988S	viability after 35 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	1.012721887898525	[1586]	[1355,1222,NaN]	9	hSpCas9	negative selection	9828698
45525600	45525623	22	+	27869803	PATU8988S	viability after 35 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.7788653173396414	[795]	[119,253,NaN]	-6	hSpCas9	negative selection	9828699
45527948	45527971	22	+	27869803	PATU8988S	viability after 35 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.06986176902245123	[237]	[148,51,NaN]	0	hSpCas9	negative selection	9828700
45531303	45531326	22	+	27869803	PATU8988S	viability after 35 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.1229322354697722	[464]	[163,179,NaN]	-1	hSpCas9	negative selection	9828701
45533088	45533111	22	+	27869803	PATU8988S	viability after 35 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	-0.1303285521629105	[1075]	[363,427,NaN]	-1	hSpCas9	negative selection	9828702
45518710	45518733	22	+	27869803	PATU8988S	viability after 31 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.8688927548314757	[291]	[198,229,NaN]	8	hSpCas9	negative selection	9911146
45523130	45523153	22	+	27869803	PATU8988S	viability after 31 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.9247688954725883	[1586]	[1133,1286,NaN]	9	hSpCas9	negative selection	9911147
45525600	45525623	22	+	27869803	PATU8988S	viability after 31 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.6905654199868834	[795]	[120,292,NaN]	-6	hSpCas9	negative selection	9911148
45527948	45527971	22	+	27869803	PATU8988S	viability after 31 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	0.480423565139791	[237]	[138,123,NaN]	6	hSpCas9	negative selection	9911149
45531303	45531326	22	+	27869803	PATU8988S	viability after 31 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	-0.41996845182877696	[464]	[76,216,NaN]	-5	hSpCas9	negative selection	9911150
45533088	45533111	22	+	27869803	PATU8988S	viability after 31 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.4227756757376351	[1075]	[480,694,NaN]	5	hSpCas9	negative selection	9911151
45518710	45518733	22	+	27869803	HPAFII	viability after 35 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	0.6873012013519971	[237]	[106,291,NaN]	4	hSpCas9	negative selection	9993595
45523130	45523153	22	+	27869803	HPAFII	viability after 35 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.10426365842256535	[707]	[365,406,NaN]	0	hSpCas9	negative selection	9993596
45525600	45525623	22	+	27869803	HPAFII	viability after 35 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.8030613166903495	[289]	[133,27,NaN]	-5	hSpCas9	negative selection	9993597
45527948	45527971	22	+	27869803	HPAFII	viability after 35 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	-0.05710087786288276	[99]	[74,18,NaN]	0	hSpCas9	negative selection	9993598
45531303	45531326	22	+	27869803	HPAFII	viability after 35 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.9395486823757234	[130]	[161,87,NaN]	6	hSpCas9	negative selection	9993599
45533088	45533111	22	+	27869803	HPAFII	viability after 35 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.5445533847770274	[429]	[158,495,NaN]	3	hSpCas9	negative selection	9993600
45518710	45518733	22	+	27869803	HPAFII	viability after 31 days	CTGTGCGGACGGACACCGGATGG	FBLN1	ENSG00000077942	-0.05534092899860625	[237]	[95,163,NaN]	0	hSpCas9	negative selection	10076044
45523130	45523153	22	+	27869803	HPAFII	viability after 31 days	GGCGTGGGCAGTATGGAAAGTGG	FBLN1	ENSG00000077942	0.19872345798369584	[707]	[489,418,NaN]	1	hSpCas9	negative selection	10076045
45525600	45525623	22	+	27869803	HPAFII	viability after 31 days	CATCAGCCTGGCCAACGAGCAGG	FBLN1	ENSG00000077942	-0.5619965168765806	[289]	[137,79,NaN]	-4	hSpCas9	negative selection	10076046
45527948	45527971	22	+	27869803	HPAFII	viability after 31 days	GGCATGCTGTGTCAAGAGCCAGG	FBLN1	ENSG00000077942	-0.060184757431650304	[99]	[49,57,NaN]	0	hSpCas9	negative selection	10076047
45531303	45531326	22	+	27869803	HPAFII	viability after 31 days	TATCTGAATGACCGCTGCCGAGG	FBLN1	ENSG00000077942	0.09627449313190961	[130]	[102,51,NaN]	0	hSpCas9	negative selection	10076048
45533088	45533111	22	+	27869803	HPAFII	viability after 31 days	CCGAGACACGGGTGACGAGGTGG	FBLN1	ENSG00000077942	0.6134370928442094	[429]	[328,412,NaN]	4	hSpCas9	negative selection	10076049
45503022	45503045	22	-	28162770	P31FUJ	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.07606973764753727	[221]	[274]	0	hSpCas9	negative selection	10155633
45533877	45533900	22	+	28162770	P31FUJ	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	1.2353466313240278	[29]	[82]	9	hSpCas9	negative selection	10155634
45525576	45525599	22	+	28162770	P31FUJ	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.5816494239987561	[283]	[222]	-5	hSpCas9	negative selection	10155635
45533804	45533827	22	+	28162770	P31FUJ	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.13135412586228112	[100]	[129]	1	hSpCas9	negative selection	10155636
45535234	45535257	22	-	28162770	P31FUJ	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.5745527176432257	[75]	[132]	6	hSpCas9	negative selection	10155637
45550598	45550621	22	-	28162770	P31FUJ	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.5205578280024961	[34]	[58]	6	hSpCas9	negative selection	10155638
45518695	45518718	22	-	28162770	P31FUJ	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	0.07265225032055986	[228]	[282]	0	hSpCas9	negative selection	10155639
45525558	45525581	22	+	28162770	P31FUJ	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.003584483341789957	[481]	[564]	0	hSpCas9	negative selection	10155640
45531266	45531289	22	+	28162770	P31FUJ	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	-0.02206798826230527	[425]	[492]	0	hSpCas9	negative selection	10155641
45533861	45533884	22	+	28162770	P31FUJ	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-0.9432955872193935	[35]	[21]	-6	hSpCas9	negative selection	10155642
45503022	45503045	22	-	28162770	TF1	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	NaN	[NaN]	[344]	1	hSpCas9	negative selection	10324999
45533877	45533900	22	+	28162770	TF1	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10325000
45525576	45525599	22	+	28162770	TF1	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10325001
45533804	45533827	22	+	28162770	TF1	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10325002
45535234	45535257	22	-	28162770	TF1	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10325003
45550598	45550621	22	-	28162770	TF1	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10325004
45518695	45518718	22	-	28162770	TF1	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10325005
45525558	45525581	22	+	28162770	TF1	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	NaN	[NaN]	[341]	1	hSpCas9	negative selection	10325006
45531266	45531289	22	+	28162770	TF1	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	NaN	[NaN]	[482]	1	hSpCas9	negative selection	10325007
45533861	45533884	22	+	28162770	TF1	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10325008
45503022	45503045	22	-	28162770	SKM1	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	-0.046041972239935836	[72]	[124]	0	hSpCas9	negative selection	10494365
45533877	45533900	22	+	28162770	SKM1	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	1.4634005208402427	[7]	[38]	9	hSpCas9	negative selection	10494366
45525576	45525599	22	+	28162770	SKM1	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.24574290861382864	[103]	[217]	2	hSpCas9	negative selection	10494367
45533804	45533827	22	+	28162770	SKM1	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.499926396865357	[23]	[59]	5	hSpCas9	negative selection	10494368
45535234	45535257	22	-	28162770	SKM1	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-0.45003292063504774	[16]	[21]	-4	hSpCas9	negative selection	10494369
45550598	45550621	22	-	28162770	SKM1	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.17799830197799427	[8]	[17]	1	hSpCas9	negative selection	10494370
45518695	45518718	22	-	28162770	SKM1	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	0.45810622117072974	[62]	[152]	4	hSpCas9	negative selection	10494371
45525558	45525581	22	+	28162770	SKM1	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.34178002998302426	[118]	[165]	-3	hSpCas9	negative selection	10494372
45531266	45531289	22	+	28162770	SKM1	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	1.3740634408840968	[78]	[361]	9	hSpCas9	negative selection	10494373
45533861	45533884	22	+	28162770	SKM1	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	0.11659775731385125	[11]	[22]	1	hSpCas9	negative selection	10494374
45503022	45503045	22	-	28162770	SKM1	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	-0.046041972239935836	[72]	[124]	0	hSpCas9	negative selection	10663731
45533877	45533900	22	+	28162770	SKM1	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	1.4634005208402427	[7]	[38]	9	hSpCas9	negative selection	10663732
45525576	45525599	22	+	28162770	SKM1	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.24574290861382864	[103]	[217]	2	hSpCas9	negative selection	10663733
45533804	45533827	22	+	28162770	SKM1	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.499926396865357	[23]	[59]	5	hSpCas9	negative selection	10663734
45535234	45535257	22	-	28162770	SKM1	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-0.45003292063504774	[16]	[21]	-4	hSpCas9	negative selection	10663735
45550598	45550621	22	-	28162770	SKM1	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.17799830197799427	[8]	[17]	1	hSpCas9	negative selection	10663736
45518695	45518718	22	-	28162770	SKM1	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	0.45810622117072974	[62]	[152]	4	hSpCas9	negative selection	10663737
45525558	45525581	22	+	28162770	SKM1	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.34178002998302426	[118]	[165]	-3	hSpCas9	negative selection	10663738
45531266	45531289	22	+	28162770	SKM1	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	1.3740634408840968	[78]	[361]	9	hSpCas9	negative selection	10663739
45533861	45533884	22	+	28162770	SKM1	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	0.11659775731385125	[11]	[22]	1	hSpCas9	negative selection	10663740
45503022	45503045	22	-	28162770	PL21	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	-0.2685358483915969	[273]	[98]	-2	hSpCas9	negative selection	10833097
45533877	45533900	22	+	28162770	PL21	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	0.77564178596141	[50]	[37]	6	hSpCas9	negative selection	10833098
45525576	45525599	22	+	28162770	PL21	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.5646757626037588	[400]	[117]	-4	hSpCas9	negative selection	10833099
45533804	45533827	22	+	28162770	PL21	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.3229963622748536	[89]	[48]	3	hSpCas9	negative selection	10833100
45535234	45535257	22	-	28162770	PL21	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	1.0409410196400661	[66]	[59]	8	hSpCas9	negative selection	10833101
45550598	45550621	22	-	28162770	PL21	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	2.9189578619452665	[23]	[78]	9	hSpCas9	negative selection	10833102
45518695	45518718	22	-	28162770	PL21	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.34919897650111476	[119]	[40]	-3	hSpCas9	negative selection	10833103
45525558	45525581	22	+	28162770	PL21	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	0.47121133938853244	[357]	[215]	4	hSpCas9	negative selection	10833104
45531266	45531289	22	+	28162770	PL21	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	-0.22330032578522074	[286]	[106]	-2	hSpCas9	negative selection	10833105
45533861	45533884	22	+	28162770	PL21	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	2.2001396144893204	[24]	[49]	9	hSpCas9	negative selection	10833106
45503022	45503045	22	-	28162770	P31FUJ	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.07606973764753727	[221]	[274]	0	hSpCas9	negative selection	11002463
45533877	45533900	22	+	28162770	P31FUJ	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	1.2353466313240278	[29]	[82]	9	hSpCas9	negative selection	11002464
45525576	45525599	22	+	28162770	P31FUJ	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.5816494239987561	[283]	[222]	-5	hSpCas9	negative selection	11002465
45533804	45533827	22	+	28162770	P31FUJ	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.13135412586228112	[100]	[129]	1	hSpCas9	negative selection	11002466
45535234	45535257	22	-	28162770	P31FUJ	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.5745527176432257	[75]	[132]	6	hSpCas9	negative selection	11002467
45550598	45550621	22	-	28162770	P31FUJ	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.5205578280024961	[34]	[58]	6	hSpCas9	negative selection	11002468
45518695	45518718	22	-	28162770	P31FUJ	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	0.07265225032055986	[228]	[282]	0	hSpCas9	negative selection	11002469
45525558	45525581	22	+	28162770	P31FUJ	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.003584483341789957	[481]	[564]	0	hSpCas9	negative selection	11002470
45531266	45531289	22	+	28162770	P31FUJ	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	-0.02206798826230527	[425]	[492]	0	hSpCas9	negative selection	11002471
45533861	45533884	22	+	28162770	P31FUJ	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-0.9432955872193935	[35]	[21]	-6	hSpCas9	negative selection	11002472
45503022	45503045	22	-	28162770	OCIAML5	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	1.0647394936096042	[115]	[437]	8	hSpCas9	negative selection	11171829
45533877	45533900	22	+	28162770	OCIAML5	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	0.36294632010685324	[27]	[64]	3	hSpCas9	negative selection	11171830
45525576	45525599	22	+	28162770	OCIAML5	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.10449416787110566	[117]	[228]	0	hSpCas9	negative selection	11171831
45533804	45533827	22	+	28162770	OCIAML5	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.9219297542471763	[49]	[170]	7	hSpCas9	negative selection	11171832
45535234	45535257	22	-	28162770	OCIAML5	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.42970439755138257	[50]	[123]	3	hSpCas9	negative selection	11171833
45550598	45550621	22	-	28162770	OCIAML5	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	1.708648383610482	[9]	[58]	9	hSpCas9	negative selection	11171834
45518695	45518718	22	-	28162770	OCIAML5	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.8034863904189353	[145]	[150]	-5	hSpCas9	negative selection	11171835
45525558	45525581	22	+	28162770	OCIAML5	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	0.08131517520084053	[276]	[528]	0	hSpCas9	negative selection	11171836
45531266	45531289	22	+	28162770	OCIAML5	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.525604075950362	[263]	[685]	4	hSpCas9	negative selection	11171837
45533861	45533884	22	+	28162770	OCIAML5	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-0.5719586516712618	[27]	[33]	-4	hSpCas9	negative selection	11171838
45503022	45503045	22	-	28162770	EOL1	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	1.1009743389548021	[368]	[416]	8	hSpCas9	negative selection	11341195
45533877	45533900	22	+	28162770	EOL1	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	-0.2505389349875564	[69]	[30]	-2	hSpCas9	negative selection	11341196
45525576	45525599	22	+	28162770	EOL1	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.1996866640671504	[632]	[382]	1	hSpCas9	negative selection	11341197
45533804	45533827	22	+	28162770	EOL1	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.6558446156500488	[152]	[126]	6	hSpCas9	negative selection	11341198
45535234	45535257	22	-	28162770	EOL1	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	1.0567955698689742	[124]	[136]	8	hSpCas9	negative selection	11341199
45550598	45550621	22	-	28162770	EOL1	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	1.246475866457897	[51]	[64]	9	hSpCas9	negative selection	11341200
45518695	45518718	22	-	28162770	EOL1	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.5205917594977285	[225]	[82]	-4	hSpCas9	negative selection	11341201
45525558	45525581	22	+	28162770	EOL1	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.5072368025454623	[490]	[181]	-4	hSpCas9	negative selection	11341202
45531266	45531289	22	+	28162770	EOL1	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	1.0908705363326514	[400]	[449]	8	hSpCas9	negative selection	11341203
45533861	45533884	22	+	28162770	EOL1	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-3.4677696512082257	[20]	[0]	-9	hSpCas9	negative selection	11341204
45503022	45503045	22	-	28162770	MOLM13	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	-0.5086516456314323	[304]	[154]	-3	hSpCas9	negative selection	11510561
45533877	45533900	22	+	28162770	MOLM13	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	-0.42777395864068546	[79]	[42]	-3	hSpCas9	negative selection	11510562
45525576	45525599	22	+	28162770	MOLM13	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.7146551064288473	[487]	[214]	-4	hSpCas9	negative selection	11510563
45533804	45533827	22	+	28162770	MOLM13	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.3615804793982382	[182]	[169]	2	hSpCas9	negative selection	11510564
45535234	45535257	22	-	28162770	MOLM13	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.7573959987395635	[125]	[153]	6	hSpCas9	negative selection	11510565
45550598	45550621	22	-	28162770	MOLM13	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.8280649457889044	[66]	[85]	6	hSpCas9	negative selection	11510566
45518695	45518718	22	-	28162770	MOLM13	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.5139632717451619	[236]	[119]	-3	hSpCas9	negative selection	11510567
45525558	45525581	22	+	28162770	MOLM13	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.06133056724958097	[494]	[342]	0	hSpCas9	negative selection	11510568
45531266	45531289	22	+	28162770	MOLM13	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.6952395226769944	[497]	[582]	5	hSpCas9	negative selection	11510569
45533861	45533884	22	+	28162770	MOLM13	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	2.1026049174628345	[18]	[58]	9	hSpCas9	negative selection	11510570
45503022	45503045	22	-	28162770	HEL	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.3461218256421821	[338]	[275]	3	hSpCas9	negative selection	11679927
45533877	45533900	22	+	28162770	HEL	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	0.46870943222530803	[43]	[38]	4	hSpCas9	negative selection	11679928
45525576	45525599	22	+	28162770	HEL	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.26331517614436584	[430]	[229]	-2	hSpCas9	negative selection	11679929
45533804	45533827	22	+	28162770	HEL	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.7184031019324293	[129]	[136]	6	hSpCas9	negative selection	11679930
45535234	45535257	22	-	28162770	HEL	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.7338867200585522	[91]	[97]	6	hSpCas9	negative selection	11679931
45550598	45550621	22	-	28162770	HEL	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.8808985691951217	[38]	[45]	7	hSpCas9	negative selection	11679932
45518695	45518718	22	-	28162770	HEL	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.09946341053199625	[183]	[109]	0	hSpCas9	negative selection	11679933
45525558	45525581	22	+	28162770	HEL	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.41143630815068205	[406]	[195]	-3	hSpCas9	negative selection	11679934
45531266	45531289	22	+	28162770	HEL	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	-0.16117700609047603	[418]	[239]	-1	hSpCas9	negative selection	11679935
45533861	45533884	22	+	28162770	HEL	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-0.009337864579336053	[32]	[20]	0	hSpCas9	negative selection	11679936
45503022	45503045	22	-	28162770	MV411	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.1983430012546058	[268]	[259]	1	hSpCas9	negative selection	11849293
45533877	45533900	22	+	28162770	MV411	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	-0.14849112554836408	[49]	[37]	-1	hSpCas9	negative selection	11849294
45525576	45525599	22	+	28162770	MV411	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.6450780225508195	[361]	[194]	-4	hSpCas9	negative selection	11849295
45533804	45533827	22	+	28162770	MV411	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	-0.20425841907491682	[92]	[67]	-1	hSpCas9	negative selection	11849296
45535234	45535257	22	-	28162770	MV411	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.12370218236053043	[72]	[66]	1	hSpCas9	negative selection	11849297
45550598	45550621	22	-	28162770	MV411	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	-1.118211921533905	[66]	[25]	-6	hSpCas9	negative selection	11849298
45518695	45518718	22	-	28162770	MV411	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.10912754577660438	[136]	[106]	-1	hSpCas9	negative selection	11849299
45525558	45525581	22	+	28162770	MV411	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.6413725902003871	[336]	[181]	-4	hSpCas9	negative selection	11849300
45531266	45531289	22	+	28162770	MV411	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	-0.3024424907829354	[324]	[221]	-2	hSpCas9	negative selection	11849301
45533861	45533884	22	+	28162770	MV411	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	0.7543975395026585	[18]	[26]	6	hSpCas9	negative selection	11849302
45503022	45503045	22	-	28162770	MONOMAC1	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.0003213845058710474	[190]	[218]	0	hSpCas9	negative selection	12018659
45533877	45533900	22	+	28162770	MONOMAC1	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	0.21800065221928988	[32]	[43]	2	hSpCas9	negative selection	12018660
45525576	45525599	22	+	28162770	MONOMAC1	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.42288932591643336	[230]	[354]	4	hSpCas9	negative selection	12018661
45533804	45533827	22	+	28162770	MONOMAC1	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	2.0971462573449045	[62]	[308]	9	hSpCas9	negative selection	12018662
45535234	45535257	22	-	28162770	MONOMAC1	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-0.5913157861716003	[45]	[34]	-5	hSpCas9	negative selection	12018663
45550598	45550621	22	-	28162770	MONOMAC1	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	0.407034476609307	[24]	[37]	4	hSpCas9	negative selection	12018664
45518695	45518718	22	-	28162770	MONOMAC1	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.05183893151961816	[84]	[93]	0	hSpCas9	negative selection	12018665
45525558	45525581	22	+	28162770	MONOMAC1	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	-0.5503453565866911	[243]	[190]	-5	hSpCas9	negative selection	12018666
45531266	45531289	22	+	28162770	MONOMAC1	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.11022155903092368	[256]	[317]	1	hSpCas9	negative selection	12018667
45533861	45533884	22	+	28162770	MONOMAC1	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	1.446819342715171	[7]	[24]	9	hSpCas9	negative selection	12018668
45503022	45503045	22	-	28162770	OCIAML2	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.31637645142364057	[50]	[351]	3	hSpCas9	negative selection	12188025
45533877	45533900	22	+	28162770	OCIAML2	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	-0.6821339304358729	[10]	[37]	-5	hSpCas9	negative selection	12188026
45525576	45525599	22	+	28162770	OCIAML2	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	0.035402206257275415	[71]	[408]	0	hSpCas9	negative selection	12188027
45533804	45533827	22	+	28162770	OCIAML2	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	0.500611181776415	[18]	[148]	5	hSpCas9	negative selection	12188028
45535234	45535257	22	-	28162770	OCIAML2	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	0.17322636453256357	[11]	[74]	1	hSpCas9	negative selection	12188029
45550598	45550621	22	-	28162770	OCIAML2	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	1.2735312703282489	[4]	[66]	9	hSpCas9	negative selection	12188030
45518695	45518718	22	-	28162770	OCIAML2	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	-0.849141448495891	[38]	[119]	-5	hSpCas9	negative selection	12188031
45525558	45525581	22	+	28162770	OCIAML2	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	0.4579558414656764	[43]	[334]	4	hSpCas9	negative selection	12188032
45531266	45531289	22	+	28162770	OCIAML2	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.21742616844309848	[53]	[347]	2	hSpCas9	negative selection	12188033
45533861	45533884	22	+	28162770	OCIAML2	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	-2.4706298252421615	[5]	[5]	-8	hSpCas9	negative selection	12188034
45503022	45503045	22	-	28162770	OCIAML3	viability	AGGCCGCCGAGCAGCAGCAGCGG	FBLN1	ENSG00000077942	0.3997604059643224	[57]	[230]	4	hSpCas9	negative selection	12357391
45533877	45533900	22	+	28162770	OCIAML3	viability	ACAGAGGACAATAGCTGCAAAGG	FBLN1	ENSG00000077942	0.049848549450561386	[7]	[24]	0	hSpCas9	negative selection	12357392
45525576	45525599	22	+	28162770	OCIAML3	viability	GGAGGAGCTGCACTGTGCCACGG	FBLN1	ENSG00000077942	-0.4499612707074562	[99]	[220]	-3	hSpCas9	negative selection	12357393
45533804	45533827	22	+	28162770	OCIAML3	viability	AGAATCCTGCATCAACACAGTGG	FBLN1	ENSG00000077942	-0.6305335163492771	[19]	[38]	-5	hSpCas9	negative selection	12357394
45535234	45535257	22	-	28162770	OCIAML3	viability	TCTGACAGATAAAATCGGGGAGG	FBLN1	ENSG00000077942	-0.7272741711876274	[16]	[30]	-5	hSpCas9	negative selection	12357395
45550598	45550621	22	-	28162770	OCIAML3	viability	CTTACGTGGCTGCGGAGCGGCGG	FBLN1	ENSG00000077942	-3.096507980853347	[16]	[5]	-9	hSpCas9	negative selection	12357396
45518695	45518718	22	-	28162770	OCIAML3	viability	CCGCACAGCAGGCCTCCAGGAGG	FBLN1	ENSG00000077942	0.48128048698007386	[41]	[176]	4	hSpCas9	negative selection	12357397
45525558	45525581	22	+	28162770	OCIAML3	viability	GTGCTGCCACAGCCAGCTGGAGG	FBLN1	ENSG00000077942	0.47897180503294234	[105]	[445]	4	hSpCas9	negative selection	12357398
45531266	45531289	22	+	28162770	OCIAML3	viability	TAAGATCATTGAGGTTGAGGAGG	FBLN1	ENSG00000077942	0.6944739714700571	[95]	[468]	6	hSpCas9	negative selection	12357399
45533861	45533884	22	+	28162770	OCIAML3	viability	GACTGGCTATGAGCTCACAGAGG	FBLN1	ENSG00000077942	0.7279204545631996	[1]	[9]	6	hSpCas9	negative selection	12357400