Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2201
• Symbol:FBN2
• Description:fibrillin 2

DataSource: http://genomecrispr.dkfz.de/#!/results/FBN2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
128395210	128395233	5	-	26472758	Jiyoye	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.07875352453301065	[166]	[132]	0	hSpCas9	negative selection	56410
128345393	128345416	5	+	26472758	Jiyoye	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	-0.8152170398305746	[230]	[98]	-5	hSpCas9	negative selection	56411
128345513	128345536	5	+	26472758	Jiyoye	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-1.660996121135706	[129]	[30]	-8	hSpCas9	negative selection	56412
128537455	128537478	5	+	26472758	Jiyoye	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	-0.26820241443750104	[213]	[133]	-2	hSpCas9	negative selection	56413
128527934	128527957	5	-	26472758	Jiyoye	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.22863724975885313	[566]	[500]	1	hSpCas9	negative selection	56414
128446578	128446601	5	-	26472758	Jiyoye	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	-0.26290373285323354	[287]	[180]	-2	hSpCas9	negative selection	56415
128393308	128393331	5	-	26472758	Jiyoye	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	1.2551722880608234	[44]	[80]	7	hSpCas9	negative selection	56416
128378796	128378819	5	-	26472758	Jiyoye	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.4071753815058734	[59]	[59]	3	hSpCas9	negative selection	56417
128361743	128361766	5	+	26472758	Jiyoye	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	4.7994928042846325	[0]	[20]	9	hSpCas9	negative selection	56418
128357338	128357361	5	-	26472758	Jiyoye	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	2.4071753815058736	[7]	[31]	9	hSpCas9	negative selection	56419
128395210	128395233	5	-	26472758	KBM7	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.12333499801931824	[568,399]	[321,175]	1	hSpCas9	negative selection	247528
128345393	128345416	5	+	26472758	KBM7	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.45556765523883963	[324,272]	[238,149]	5	hSpCas9	negative selection	247529
128345513	128345536	5	+	26472758	KBM7	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	0.7692747135947904	[175,206]	[202,112]	8	hSpCas9	negative selection	247530
128537455	128537478	5	+	26472758	KBM7	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.17292071111516585	[751,356]	[281,286]	1	hSpCas9	negative selection	247531
128527934	128527957	5	-	26472758	KBM7	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.6828099763554536	[2251,1770]	[2015,1051]	7	hSpCas9	negative selection	247532
128446578	128446601	5	-	26472758	KBM7	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	1.4319159471408134	[970,611]	[717,1224]	9	hSpCas9	negative selection	247533
128393308	128393331	5	-	26472758	KBM7	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.3990457733581963	[571,456]	[101,253]	-4	hSpCas9	negative selection	247534
128378796	128378819	5	-	26472758	KBM7	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.8515568386543869	[419,338]	[394,252]	8	hSpCas9	negative selection	247535
128361743	128361766	5	+	26472758	KBM7	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.5620399179816677	[151,123]	[127,65]	6	hSpCas9	negative selection	247536
128357338	128357361	5	-	26472758	KBM7	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.8606181996522491	[148,105]	[163,56]	8	hSpCas9	negative selection	247537
128395210	128395233	5	-	26472758	Raji	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	1.6646010456118514	[139]	[102]	9	hSpCas9	negative selection	438646
128345393	128345416	5	+	26472758	Raji	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.24266239400902062	[294]	[80]	2	hSpCas9	negative selection	438647
128345513	128345536	5	+	26472758	Raji	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-1.0876324470315433	[173]	[18]	-7	hSpCas9	negative selection	438648
128537455	128537478	5	+	26472758	Raji	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.43533541788873187	[238]	[74]	4	hSpCas9	negative selection	438649
128527934	128527957	5	-	26472758	Raji	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	-0.0502526776206067	[1168]	[261]	0	hSpCas9	negative selection	438650
128446578	128446601	5	-	26472758	Raji	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.27849545176635404	[404]	[113]	2	hSpCas9	negative selection	438651
128393308	128393331	5	-	26472758	Raji	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.37911632646186844	[268]	[47]	-3	hSpCas9	negative selection	438652
128378796	128378819	5	-	26472758	Raji	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.7613237780133391	[210]	[82]	7	hSpCas9	negative selection	438653
128361743	128361766	5	+	26472758	Raji	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	-0.04461955807145057	[79]	[17]	0	hSpCas9	negative selection	438654
128357338	128357361	5	-	26472758	Raji	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	-0.18923347098457555	[112]	[22]	-1	hSpCas9	negative selection	438655
128395210	128395233	5	-	26472758	K562	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	-0.007823621416561177	[292]	[245]	0	hSpCas9	negative selection	629764
128345393	128345416	5	+	26472758	K562	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.6413915111832991	[220]	[290]	5	hSpCas9	negative selection	629765
128345513	128345536	5	+	26472758	K562	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-0.19888262383111832	[188]	[138]	-1	hSpCas9	negative selection	629766
128537455	128537478	5	+	26472758	K562	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.07759963709195616	[521]	[464]	0	hSpCas9	negative selection	629767
128527934	128527957	5	-	26472758	K562	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.5458508588822317	[2069]	[2550]	4	hSpCas9	negative selection	629768
128446578	128446601	5	-	26472758	K562	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.30818327019553926	[685]	[716]	2	hSpCas9	negative selection	629769
128393308	128393331	5	-	26472758	K562	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.21680840463246445	[401]	[291]	-1	hSpCas9	negative selection	629770
128378796	128378819	5	-	26472758	K562	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	1.5538558783706122	[231]	[574]	9	hSpCas9	negative selection	629771
128361743	128361766	5	+	26472758	K562	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.7164871719816694	[92]	[128]	6	hSpCas9	negative selection	629772
128357338	128357361	5	-	26472758	K562	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.7556715422045936	[86]	[123]	6	hSpCas9	negative selection	629773
128446502	128446525	5	+	26627737	DLD1	viability	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.14973405197056455	[1154]	[453,314,424]	1	hSpCas9	negative selection	826692
128519297	128519320	5	+	26627737	DLD1	viability	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-0.006265577070156292	[670]	[249,202,177]	0	hSpCas9	negative selection	826693
128527909	128527932	5	+	26627737	DLD1	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.38442684872373833	[174]	[52,63,13]	-4	hSpCas9	negative selection	826694
128530611	128530634	5	+	26627737	DLD1	viability	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.27576684302447063	[119]	[18,17,90]	3	hSpCas9	negative selection	826695
128536393	128536416	5	+	26627737	DLD1	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.19226141691420917	[1132]	[306,271,343]	-2	hSpCas9	negative selection	826696
128537458	128537481	5	+	26627737	DLD1	viability	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	1.050463498447295	[262]	[115,224,171]	8	hSpCas9	negative selection	826697
128446502	128446525	5	+	26627737	GBM cells	viability after 5 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.03412030124550958	[441]	[206,255]	0	hSpCas9	negative selection	909007
128519297	128519320	5	+	26627737	GBM cells	viability after 5 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.04707928212848844	[526]	[307,275]	0	hSpCas9	negative selection	909008
128527909	128527932	5	+	26627737	GBM cells	viability after 5 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.3516295867649113	[68]	[42,14]	-5	hSpCas9	negative selection	909009
128530611	128530634	5	+	26627737	GBM cells	viability after 5 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.8989138748856857	[51]	[30,72]	9	hSpCas9	negative selection	909010
128536393	128536416	5	+	26627737	GBM cells	viability after 5 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.10108612511431436	[393]	[197,195]	-1	hSpCas9	negative selection	909011
128537458	128537481	5	+	26627737	GBM cells	viability after 5 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.5633108431012466	[105]	[87,79]	7	hSpCas9	negative selection	909012
128446502	128446525	5	+	26627737	GBM cells	viability after 13 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.023850601575673647	[441]	[293,202]	0	hSpCas9	negative selection	991322
128519297	128519320	5	+	26627737	GBM cells	viability after 13 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.2595056700661931	[526]	[290,383]	3	hSpCas9	negative selection	991323
128527909	128527932	5	+	26627737	GBM cells	viability after 13 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-1.2297401638349168	[68]	[10,19]	-8	hSpCas9	negative selection	991324
128530611	128530634	5	+	26627737	GBM cells	viability after 13 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	1.108395431001515	[51]	[67,54]	9	hSpCas9	negative selection	991325
128536393	128536416	5	+	26627737	GBM cells	viability after 13 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.34114214278023486	[393]	[165,170]	-4	hSpCas9	negative selection	991326
128537458	128537481	5	+	26627737	GBM cells	viability after 13 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.7362692912204056	[105]	[129,67]	8	hSpCas9	negative selection	991327
128446502	128446525	5	+	26627737	GBM cells	viability after 21 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.548251540064373	[441]	[382,321]	5	hSpCas9	negative selection	1073637
128519297	128519320	5	+	26627737	GBM cells	viability after 21 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.5955381109272713	[526]	[417,445]	6	hSpCas9	negative selection	1073638
128527909	128527932	5	+	26627737	GBM cells	viability after 21 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.44809772910224765	[68]	[27,26]	-4	hSpCas9	negative selection	1073639
128530611	128530634	5	+	26627737	GBM cells	viability after 21 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	1.6306382480316486	[51]	[87,86]	9	hSpCas9	negative selection	1073640
128536393	128536416	5	+	26627737	GBM cells	viability after 21 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.2424155168871267	[393]	[193,168]	-2	hSpCas9	negative selection	1073641
128537458	128537481	5	+	26627737	GBM cells	viability after 21 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.6902645963534819	[105]	[82,101]	7	hSpCas9	negative selection	1073642
128446502	128446525	5	+	26627737	RPE1	viability after 9 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.5271276804455415	[1261]	[340,863]	3	hSpCas9	negative selection	1155952
128519297	128519320	5	+	26627737	RPE1	viability after 9 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.9274779928156633	[1081]	[559,752]	6	hSpCas9	negative selection	1155953
128527909	128527932	5	+	26627737	RPE1	viability after 9 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	5.491483695472224	[1]	[18,39]	9	hSpCas9	negative selection	1155954
128530611	128530634	5	+	26627737	RPE1	viability after 9 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	1.8580157410093552	[63]	[76,66]	8	hSpCas9	negative selection	1155955
128536393	128536416	5	+	26627737	RPE1	viability after 9 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.18212807843827172	[2005]	[415,730]	-1	hSpCas9	negative selection	1155956
128537458	128537481	5	+	26627737	RPE1	viability after 9 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.05056031924856433	[704]	[175,260]	0	hSpCas9	negative selection	1155957
128446502	128446525	5	+	26627737	RPE1	viability after 12 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.9847227410935825	[1261]	[584,761]	6	hSpCas9	negative selection	1238267
128519297	128519320	5	+	26627737	RPE1	viability after 12 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.8676413056434586	[1081]	[442,622]	5	hSpCas9	negative selection	1238268
128527909	128527932	5	+	26627737	RPE1	viability after 12 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	6.174096158972903	[1]	[31,45]	9	hSpCas9	negative selection	1238269
128530611	128530634	5	+	26627737	RPE1	viability after 12 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	1.886418015469294	[63]	[48,78]	8	hSpCas9	negative selection	1238270
128536393	128536416	5	+	26627737	RPE1	viability after 12 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.6390088979484978	[2005]	[331,360]	-4	hSpCas9	negative selection	1238271
128537458	128537481	5	+	26627737	RPE1	viability after 12 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.5144310703877928	[704]	[152,110]	-4	hSpCas9	negative selection	1238272
128446502	128446525	5	+	26627737	RPE1	viability after 15 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	1.4330404342839933	[1261]	[798,1122]	7	hSpCas9	negative selection	1320582
128519297	128519320	5	+	26627737	RPE1	viability after 15 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.1494501313996603	[1081]	[652,703]	6	hSpCas9	negative selection	1320583
128527909	128527932	5	+	26627737	RPE1	viability after 15 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	5.679617312335404	[1]	[0,55]	9	hSpCas9	negative selection	1320584
128530611	128530634	5	+	26627737	RPE1	viability after 15 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	2.5968637882286814	[63]	[79,137]	9	hSpCas9	negative selection	1320585
128536393	128536416	5	+	26627737	RPE1	viability after 15 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.06482969462733412	[2005]	[675,513]	0	hSpCas9	negative selection	1320586
128537458	128537481	5	+	26627737	RPE1	viability after 15 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.12545833343673818	[704]	[192,172]	-1	hSpCas9	negative selection	1320587
128446502	128446525	5	+	26627737	RPE1	viability after 18 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	1.4547478583808617	[1261]	[759,1118]	7	hSpCas9	negative selection	1402897
128519297	128519320	5	+	26627737	RPE1	viability after 18 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.0883246122057084	[1081]	[514,733]	6	hSpCas9	negative selection	1402898
128527909	128527932	5	+	26627737	RPE1	viability after 18 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	3.5490301364825303	[1]	[0,11]	9	hSpCas9	negative selection	1402899
128530611	128530634	5	+	26627737	RPE1	viability after 18 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	2.823820262076394	[63]	[86,159]	9	hSpCas9	negative selection	1402900
128536393	128536416	5	+	26627737	RPE1	viability after 18 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.1302445526102154	[2005]	[337,661]	-1	hSpCas9	negative selection	1402901
128537458	128537481	5	+	26627737	RPE1	viability after 18 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.5771092182168249	[704]	[142,110]	-4	hSpCas9	negative selection	1402902
128446502	128446525	5	+	26627737	HeLa	viability after 8 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.12493138678407456	[787]	[343,204,394]	-1	hSpCas9	negative selection	1485212
128519297	128519320	5	+	26627737	HeLa	viability after 8 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.229898135905263	[374]	[649,351,216]	8	hSpCas9	negative selection	1485213
128527909	128527932	5	+	26627737	HeLa	viability after 8 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.3789784432448522	[162]	[6,40,201]	3	hSpCas9	negative selection	1485214
128530611	128530634	5	+	26627737	HeLa	viability after 8 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	1.71423643265034	[58]	[25,145,68]	9	hSpCas9	negative selection	1485215
128536393	128536416	5	+	26627737	HeLa	viability after 8 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.1579487863498002	[451]	[128,283,224]	1	hSpCas9	negative selection	1485216
128537458	128537481	5	+	26627737	HeLa	viability after 8 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.6563186278141188	[595]	[244,140,127]	-6	hSpCas9	negative selection	1485217
128446502	128446525	5	+	26627737	HeLa	viability after 12 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.29406576434010123	[787]	[456,205,556]	2	hSpCas9	negative selection	1567527
128519297	128519320	5	+	26627737	HeLa	viability after 12 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.14576850853853374	[374]	[227,161,126]	1	hSpCas9	negative selection	1567528
128527909	128527932	5	+	26627737	HeLa	viability after 12 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.13851110292426383	[162]	[58,111,46]	1	hSpCas9	negative selection	1567529
128530611	128530634	5	+	26627737	HeLa	viability after 12 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	1.2252678794336647	[58]	[74,80,12]	8	hSpCas9	negative selection	1567530
128536393	128536416	5	+	26627737	HeLa	viability after 12 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.18759394867033902	[451]	[189,198,249]	1	hSpCas9	negative selection	1567531
128537458	128537481	5	+	26627737	HeLa	viability after 12 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.14219511829946307	[595]	[329,153,195]	-1	hSpCas9	negative selection	1567532
128446502	128446525	5	+	26627737	HeLa	viability after 15 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.2621315320213913	[787]	[313,287,566]	2	hSpCas9	negative selection	1649842
128519297	128519320	5	+	26627737	HeLa	viability after 15 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.5588040939979215	[374]	[765,300,263]	8	hSpCas9	negative selection	1649843
128527909	128527932	5	+	26627737	HeLa	viability after 15 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.6137529238031312	[162]	[116,78,108]	5	hSpCas9	negative selection	1649844
128530611	128530634	5	+	26627737	HeLa	viability after 15 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.7394099325406682	[58]	[74,14,28]	6	hSpCas9	negative selection	1649845
128536393	128536416	5	+	26627737	HeLa	viability after 15 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.44434102254697155	[451]	[237,169,350]	3	hSpCas9	negative selection	1649846
128537458	128537481	5	+	26627737	HeLa	viability after 15 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-1.145413294008896	[595]	[87,183,52]	-7	hSpCas9	negative selection	1649847
128446502	128446525	5	+	26627737	HeLa	viability after 18 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.27123907156539273	[787]	[210,243,566]	2	hSpCas9	negative selection	1732157
128519297	128519320	5	+	26627737	HeLa	viability after 18 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.5879439373720208	[374]	[527,253,263]	8	hSpCas9	negative selection	1732158
128527909	128527932	5	+	26627737	HeLa	viability after 18 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.6236929060060883	[162]	[80,63,108]	5	hSpCas9	negative selection	1732159
128530611	128530634	5	+	26627737	HeLa	viability after 18 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.7008169952891379	[58]	[46,13,28]	5	hSpCas9	negative selection	1732160
128536393	128536416	5	+	26627737	HeLa	viability after 18 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.44818150113532257	[451]	[155,146,350]	3	hSpCas9	negative selection	1732161
128537458	128537481	5	+	26627737	HeLa	viability after 18 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-1.2241393985579117	[595]	[51,146,52]	-8	hSpCas9	negative selection	1732162
128446502	128446525	5	+	26627737	HCT116	viability after 6 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	1.113742275662682	[1117]	[953,63]	6	hSpCas9	negative selection	1814472
128519297	128519320	5	+	26627737	HCT116	viability after 6 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-0.1657988234117138	[833]	[190,75]	-1	hSpCas9	negative selection	1814473
128527909	128527932	5	+	26627737	HCT116	viability after 6 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.3052618783986536	[77]	[38,1]	1	hSpCas9	negative selection	1814474
128530611	128530634	5	+	26627737	HCT116	viability after 6 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.10460195308288789	[211]	[98,0]	0	hSpCas9	negative selection	1814475
128536393	128536416	5	+	26627737	HCT116	viability after 6 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.24096896556712866	[1125]	[379,114]	1	hSpCas9	negative selection	1814476
128537458	128537481	5	+	26627737	HCT116	viability after 6 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	1.110218675313127	[497]	[382,50]	6	hSpCas9	negative selection	1814477
128446502	128446525	5	+	26627737	HCT116	viability after 8 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.5730956027735182	[680]	[176,296,280]	-6	hSpCas9	negative selection	1896787
128519297	128519320	5	+	26627737	HCT116	viability after 8 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.3797442962863906	[193]	[294,275,263]	9	hSpCas9	negative selection	1896788
128527909	128527932	5	+	26627737	HCT116	viability after 8 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.29261205614111807	[69]	[41,81,17]	3	hSpCas9	negative selection	1896789
128530611	128530634	5	+	26627737	HCT116	viability after 8 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-0.09904957816146154	[90]	[16,82,39]	-1	hSpCas9	negative selection	1896790
128536393	128536416	5	+	26627737	HCT116	viability after 8 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.7776485486758781	[494]	[101,190,182]	-7	hSpCas9	negative selection	1896791
128537458	128537481	5	+	26627737	HCT116	viability after 8 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.03761642582516229	[290]	[169,149,148]	0	hSpCas9	negative selection	1896792
128446502	128446525	5	+	26627737	HCT116	viability after 9 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.2392862954376609	[1117]	[353,172]	-2	hSpCas9	negative selection	1979102
128519297	128519320	5	+	26627737	HCT116	viability after 9 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.3746395855433182	[833]	[658,512]	8	hSpCas9	negative selection	1979103
128527909	128527932	5	+	26627737	HCT116	viability after 9 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.7956371669211095	[77]	[48,25]	5	hSpCas9	negative selection	1979104
128530611	128530634	5	+	26627737	HCT116	viability after 9 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.1427496596842559	[211]	[114,20]	1	hSpCas9	negative selection	1979105
128536393	128536416	5	+	26627737	HCT116	viability after 9 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-1.0436018018869384	[1125]	[275,42]	-6	hSpCas9	negative selection	1979106
128537458	128537481	5	+	26627737	HCT116	viability after 9 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.39560470861473934	[497]	[146,196]	3	hSpCas9	negative selection	1979107
128446502	128446525	5	+	26627737	HCT116	viability after 12 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.4232731063755054	[680]	[308,144,339]	-4	hSpCas9	negative selection	2061417
128519297	128519320	5	+	26627737	HCT116	viability after 12 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.024032371436462	[193]	[213,231,175]	8	hSpCas9	negative selection	2061418
128527909	128527932	5	+	26627737	HCT116	viability after 12 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.7090632711541753	[69]	[21,69,91]	6	hSpCas9	negative selection	2061419
128530611	128530634	5	+	26627737	HCT116	viability after 12 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-1.2339321621980774	[90]	[27,6,24]	-8	hSpCas9	negative selection	2061420
128536393	128536416	5	+	26627737	HCT116	viability after 12 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.2284235526453553	[494]	[213,458,252]	2	hSpCas9	negative selection	2061421
128537458	128537481	5	+	26627737	HCT116	viability after 12 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	-0.04516074749444892	[290]	[254,95,82]	0	hSpCas9	negative selection	2061422
128446502	128446525	5	+	26627737	HCT116	viability after 15 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.4178334796785045	[680]	[362,246,276]	-4	hSpCas9	negative selection	2143732
128519297	128519320	5	+	26627737	HCT116	viability after 15 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.2244258330059887	[193]	[372,268,153]	8	hSpCas9	negative selection	2143733
128527909	128527932	5	+	26627737	HCT116	viability after 15 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.3432797856435639	[69]	[3,68,73]	3	hSpCas9	negative selection	2143734
128530611	128530634	5	+	26627737	HCT116	viability after 15 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-0.02270928198398514	[90]	[21,97,30]	0	hSpCas9	negative selection	2143735
128536393	128536416	5	+	26627737	HCT116	viability after 15 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.29990738536043954	[494]	[216,320,153]	-3	hSpCas9	negative selection	2143736
128537458	128537481	5	+	26627737	HCT116	viability after 15 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.33695459307897524	[290]	[238,214,182]	3	hSpCas9	negative selection	2143737
128446502	128446525	5	+	26627737	HCT116	viability after 18 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.16400506170794893	[680]	[315,143,437]	-1	hSpCas9	negative selection	2226047
128519297	128519320	5	+	26627737	HCT116	viability after 18 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.362746682738953	[193]	[207,319,187]	8	hSpCas9	negative selection	2226048
128527909	128527932	5	+	26627737	HCT116	viability after 18 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.7016824619609519	[69]	[9,65,89]	6	hSpCas9	negative selection	2226049
128530611	128530634	5	+	26627737	HCT116	viability after 18 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-0.8899056653433832	[90]	[7,14,49]	-7	hSpCas9	negative selection	2226050
128536393	128536416	5	+	26627737	HCT116	viability after 18 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.20433969703546961	[494]	[269,210,353]	1	hSpCas9	negative selection	2226051
128537458	128537481	5	+	26627737	HCT116	viability after 18 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.15885743240456304	[290]	[162,198,103]	1	hSpCas9	negative selection	2226052
128346635	128346658	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTTGCCCAGACCAG	FBN2	ENSG00000138829	2.6118589352134576	[275,130]	[385,150]	8	dCas9-VP64	positive selection	2414691
128327729	128327752	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAAAATTGCTTGAACCCTGG	FBN2	ENSG00000138829	3.06787684374975	[49,8]	[78,27]	8	dCas9-VP64	positive selection	2415383
128262248	128262271	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTTGCTATGTTGCCCTAG	FBN2	ENSG00000138829	0.7258925451918798	[40,76]	[27,13]	3	dCas9-VP64	positive selection	2423511
128521334	128521357	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGAGGAACAACACACACTGG	FBN2	ENSG00000138829	1.0853496143632546	[54,123]	[41,41]	4	dCas9-VP64	positive selection	2462604
128406400	128406423	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGAGGTTGCTAAGATCTATGG	FBN2	ENSG00000138829	0.6994338305575274	[48,32]	[18,8]	3	dCas9-VP64	positive selection	2473909
128346635	128346658	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTTGCCCAGACCAG	FBN2	ENSG00000138829	-0.18468441030242128	[164,170]	[47,47]	-2	dCas9-VP64	positive selection	2509946
128327729	128327752	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAAAATTGCTTGAACCCTGG	FBN2	ENSG00000138829	0.014675341320169899	[37,72]	[27,8]	0	dCas9-VP64	positive selection	2510638
128262248	128262271	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTTGCTATGTTGCCCTAG	FBN2	ENSG00000138829	-0.28323094604648114	[112,110]	[38,20]	-3	dCas9-VP64	positive selection	2518766
128521334	128521357	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGAGGAACAACACACACTGG	FBN2	ENSG00000138829	-0.5551073257138659	[37,130]	[16,19]	-5	dCas9-VP64	positive selection	2557859
128406400	128406423	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGAGGTTGCTAAGATCTATGG	FBN2	ENSG00000138829	-0.37441963574245885	[101,43]	[16,18]	-4	dCas9-VP64	positive selection	2569164
128519298	128519321	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-0.41661418627618346	[3,3]	[2,0]	-5	hSpCas9	positive selection	2988065
128345373	128345396	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCAGTAAGAACATCCCCTCGG	FBN2	ENSG00000138829	-0.18795413437703343	[5,4]	[4,2]	-3	hSpCas9	positive selection	2988066
128349429	128349452	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCCATTTGGACAAACGCCAGGG	FBN2	ENSG00000138829	-0.08380185398015791	[4,4]	[4,2]	-1	hSpCas9	positive selection	2988067
128408695	128408718	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGAGGTTACATATCCACGTGG	FBN2	ENSG00000138829	0.1754322912552248	[3,3]	[3,3]	4	hSpCas9	positive selection	2988068
128519298	128519321	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-1.1434127959107545	[3,3]	[0,0]	-9	hSpCas9	positive selection	3055923
128345373	128345396	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCAGTAAGAACATCCCCTCGG	FBN2	ENSG00000138829	0.36721499189778767	[5,5]	[4,4]	6	hSpCas9	positive selection	3055924
128349429	128349452	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCCATTTGGACAAACGCCAGGG	FBN2	ENSG00000138829	0.041784559209076894	[4,4]	[4,1]	0	hSpCas9	positive selection	3055925
128408695	128408718	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGAGGTTACATATCCACGTGG	FBN2	ENSG00000138829	-0.26564812721414466	[3,3]	[2,1]	-4	hSpCas9	positive selection	3055926
128536393	128536416		+	24336571	A375	resistance to PLX after 7 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.13559471556609115	[11,11]	[10,14]	4	hSpCas9	positive selection	3114135
128536422	128536445		+	24336571	A375	resistance to PLX after 7 days	CCAGGGAGCGTCTTCCATCCAGG	FBN2	ENSG00000138829	-0.19554888477340088	[12,16]	[13,11]	-6	hSpCas9	positive selection	3114136
128537408	128537431		-	24336571	A375	resistance to PLX after 7 days	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.059814857885010175	[4,4]	[5,3]	2	hSpCas9	positive selection	3114137
128536393	128536416		+	24336571	A375	resistance to PLX after 14 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.12985240425293978	[14,13]	[4,6]	-1	hSpCas9	positive selection	3171928
128536422	128536445		+	24336571	A375	resistance to PLX after 14 days	CCAGGGAGCGTCTTCCATCCAGG	FBN2	ENSG00000138829	-0.6569434381883765	[10,17]	[3,3]	-7	hSpCas9	positive selection	3171929
128537408	128537431		-	24336571	A375	resistance to PLX after 14 days	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.27072689410672623	[3,4]	[1,1]	2	hSpCas9	positive selection	3171930
128536393	128536416		+	24336571	A375	viability after 7 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.22035265549390343	[14]	[11,11]	-3	hSpCas9	negative selection	3229721
128536422	128536445		+	24336571	A375	viability after 7 days	CCAGGGAGCGTCTTCCATCCAGG	FBN2	ENSG00000138829	1.0321424795331504	[7]	[12,16]	9	hSpCas9	negative selection	3229722
128537408	128537431		-	24336571	A375	viability after 7 days	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.3893819165034579	[6]	[4,4]	-5	hSpCas9	negative selection	3229723
128536393	128536416		+	24336571	A375	viability after 14 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.048976847803734486	[14]	[14,13]	0	hSpCas9	negative selection	3287514
128536422	128536445		+	24336571	A375	viability after 14 days	CCAGGGAGCGTCTTCCATCCAGG	FBN2	ENSG00000138829	1.0057304734927983	[7]	[10,17]	9	hSpCas9	negative selection	3287515
128537408	128537431		-	24336571	A375	viability after 14 days	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.5544072354039146	[6]	[3,4]	-6	hSpCas9	negative selection	3287516
128537408	128537431	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.8906040183754986	[85,78]	[0,0]	4	hSpCas9	positive selection	3349611
128537400	128537423	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	-0.4956829234815763	[248,181]	[0,0]	-3	hSpCas9	positive selection	3349612
128536470	128536493	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	-0.22438090166418181	[214,141]	[0,0]	-1	hSpCas9	positive selection	3349613
128536393	128536416	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.274055249070477	[184,184]	[0,0]	-2	hSpCas9	positive selection	3368816
128527909	128527932	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.20204377594464537	[132,132]	[0,0]	1	hSpCas9	positive selection	3368817
128527884	128527907	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	-1.4569193062202874	[419,419]	[0,0]	-8	hSpCas9	positive selection	3368818
128519297	128519320	5	+	26780180	HT29	viability (Avana library 4 designs)	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	1.09185363064639	[]	[]	4	hSpCas9	negative selection	3424958
128345372	128345395	5	+	26780180	HT29	viability (Avana library 4 designs)	GCCCAGTAAGAACATCCCCTCGG	FBN2	ENSG00000138829	0.0606454993017718	[]	[]	0	hSpCas9	negative selection	3424959
128349428	128349451	5	+	26780180	HT29	viability (Avana library 4 designs)	GTCCATTTGGACAAACGCCAGGG	FBN2	ENSG00000138829	-0.707761320600831	[]	[]	-8	hSpCas9	negative selection	3424960
128408694	128408717	5	+	26780180	HT29	viability (Avana library 4 designs)	GTTGAGGTTACATATCCACGTGG	FBN2	ENSG00000138829	0.812983974843718	[]	[]	3	hSpCas9	negative selection	3424961
128408694	128408717	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGAGGTTACATATCCACGTGG	FBN2	ENSG00000138829	1.24999313900536	[]	[]	1	hSpCas9	negative selection	3506859
128519297	128519320	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-2.34892606435397	[]	[]	-3	hSpCas9	negative selection	3506860
128345372	128345395	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCAGTAAGAACATCCCCTCGG	FBN2	ENSG00000138829	1.13048895414747	[]	[]	1	hSpCas9	negative selection	3506861
128349428	128349451	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCATTTGGACAAACGCCAGGG	FBN2	ENSG00000138829	3.32593699203499	[]	[]	5	hSpCas9	negative selection	3506862
128364662	128364685	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGATTTGTGAAAACTTACGTGG	FBN2	ENSG00000138829	1.99381785844262	[]	[]	3	hSpCas9	negative selection	3506863
128350943	128350966	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATTAATATTCACCTCACAGCGG	FBN2	ENSG00000138829	-11.4219782432709	[]	[]	-8	hSpCas9	negative selection	3506864
128408694	128408717	5	+	26780180	A375	viability (Avana lentiGuide)	GTTGAGGTTACATATCCACGTGG	FBN2	ENSG00000138829	10.9083904559696	[]	[]	7	hSpCas9	negative selection	3615518
128519297	128519320	5	+	26780180	A375	viability (Avana lentiGuide)	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-7.00070395138523	[]	[]	-9	hSpCas9	negative selection	3615519
128345372	128345395	5	+	26780180	A375	viability (Avana lentiGuide)	GCCCAGTAAGAACATCCCCTCGG	FBN2	ENSG00000138829	1.00618339773213	[]	[]	1	hSpCas9	negative selection	3615520
128349428	128349451	5	+	26780180	A375	viability (Avana lentiGuide)	GTCCATTTGGACAAACGCCAGGG	FBN2	ENSG00000138829	2.61277141537355	[]	[]	2	hSpCas9	negative selection	3615521
128364662	128364685	5	-	26780180	A375	viability (Avana lentiGuide)	GGGATTTGTGAAAACTTACGTGG	FBN2	ENSG00000138829	-3.74217397243376	[]	[]	-6	hSpCas9	negative selection	3615522
128350943	128350966	5	+	26780180	A375	viability (Avana lentiGuide)	CATTAATATTCACCTCACAGCGG	FBN2	ENSG00000138829	-1.59098936265604	[]	[]	-3	hSpCas9	negative selection	3615523
128408694	128408717	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGAGGTTACATATCCACGTGG	FBN2	ENSG00000138829	0.05150970141127914	[5]	[5,4]	1	hSpCas9	positive selection	3724177
128519297	128519320	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-0.45105544371203743	[4]	[2,3]	-6	hSpCas9	positive selection	3724178
128345372	128345395	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCAGTAAGAACATCCCCTCGG	FBN2	ENSG00000138829	-0.14954251281539652	[5]	[5,3]	-2	hSpCas9	positive selection	3724179
128349428	128349451	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCATTTGGACAAACGCCAGGG	FBN2	ENSG00000138829	0.1615090954758066	[5]	[6,5]	4	hSpCas9	positive selection	3724180
128364662	128364685	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGATTTGTGAAAACTTACGTGG	FBN2	ENSG00000138829	0.1392631601974712	[6]	[6,6]	3	hSpCas9	positive selection	3724181
128350943	128350966	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTAATATTCACCTCACAGCGG	FBN2	ENSG00000138829	-0.6253096591423135	[6]	[4,2]	-7	hSpCas9	positive selection	3724182
128408694	128408717	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGAGGTTACATATCCACGTGG	FBN2	ENSG00000138829	0.023541649974821662	[5]	[5,3]	0	hSpCas9	positive selection	3832784
128519297	128519320	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-0.1817796461562047	[4]	[3,3]	-3	hSpCas9	positive selection	3832785
128345372	128345395	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCAGTAAGAACATCCCCTCGG	FBN2	ENSG00000138829	0.01891955884795188	[6]	[5,5]	0	hSpCas9	positive selection	3832786
128349428	128349451	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCATTTGGACAAACGCCAGGG	FBN2	ENSG00000138829	0.1515052648743186	[5]	[5,5]	3	hSpCas9	positive selection	3832787
128364662	128364685	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGATTTGTGAAAACTTACGTGG	FBN2	ENSG00000138829	0.2544873237118447	[6]	[7,5]	6	hSpCas9	positive selection	3832788
128350943	128350966	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTAATATTCACCTCACAGCGG	FBN2	ENSG00000138829	0.03117405869107805	[5]	[3,5]	0	hSpCas9	positive selection	3832789
128527884	128527907	5	+	26780180	A375	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.837111317433607	[]	[]	3	hSpCas9	negative selection	3940040
128536393	128536416	5	+	26780180	A375	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	1.58919908024518	[]	[]	8	hSpCas9	negative selection	3940041
128536470	128536493	5	-	26780180	A375	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.573458409727069	[]	[]	1	hSpCas9	negative selection	3940042
128527909	128527932	5	+	26780180	A375	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	1.36790084562167	[]	[]	7	hSpCas9	negative selection	3940043
128537400	128537423	5	+	26780180	A375	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.962658852616789	[]	[]	4	hSpCas9	negative selection	3940044
128537408	128537431	5	-	26780180	A375	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.382723661848542	[]	[]	0	hSpCas9	negative selection	3940045
128527884	128527907	5	+	26780180	HT29	viability (GeCKOv2 library)	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.861671767770106	[]	[]	3	hSpCas9	negative selection	4048006
128536393	128536416	5	+	26780180	HT29	viability (GeCKOv2 library)	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	1.98707817944303	[]	[]	9	hSpCas9	negative selection	4048007
128536470	128536493	5	-	26780180	HT29	viability (GeCKOv2 library)	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.847844297896875	[]	[]	3	hSpCas9	negative selection	4048008
128527909	128527932	5	+	26780180	HT29	viability (GeCKOv2 library)	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	1.30463969151808	[]	[]	6	hSpCas9	negative selection	4048009
128537400	128537423	5	+	26780180	HT29	viability (GeCKOv2 library)	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.851415089595819	[]	[]	3	hSpCas9	negative selection	4048010
128537408	128537431	5	-	26780180	HT29	viability (GeCKOv2 library)	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.509451935290706	[]	[]	1	hSpCas9	negative selection	4048011
128536393	128536416	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.002379494227198492	[3]	[1,2]	0	hSpCas9	positive selection	4137129
128536422	128536445	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGGGAGCGTCTTCCATCCAGG	FBN2	ENSG00000138829	-0.11724640153913754	[3]	[1,1]	-3	hSpCas9	positive selection	4137130
128537408	128537431	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.42615886696140937	[2]	[0,0]	-8	hSpCas9	positive selection	4137131
128536393	128536416	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.018959903717303384	[3]	[3,1,0,0]	0	hSpCas9	positive selection	4201151
128536422	128536445	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGGGAGCGTCTTCCATCCAGG	FBN2	ENSG00000138829	1.1682997890950284	[1]	[0,0,0,3]	8	hSpCas9	positive selection	4201152
128537408	128537431	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.8610773331892299	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4201153
128537408	128537431	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.04102930734981891	[2]	[2,1]	-1	hSpCas9	positive selection	4270647
128537400	128537423	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.22436494794263176	[3]	[3,2]	4	hSpCas9	positive selection	4270648
128536470	128536493	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.3334831885987217	[3]	[3,3]	6	hSpCas9	positive selection	4270649
128536393	128536416	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.06176932087807337	[2]	[2,2]	1	hSpCas9	positive selection	4334911
128527909	128527932	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.05904834510945937	[2]	[2,1]	1	hSpCas9	positive selection	4334912
128527884	128527907	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.3208169351114605	[3]	[3,3]	6	hSpCas9	positive selection	4334913
128338998	128339020	5	-	27760321	OCIAML3	viability	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	0.7358805120829568	[472,488]	[450,861]	8	hSpCas9	negative selection	4400476
128345573	128345595	5	-	27760321	OCIAML3	viability	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	-0.516344961487293	[399,310]	[235,136]	-5	hSpCas9	negative selection	4400477
128349360	128349382	5	+	27760321	OCIAML3	viability	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	0.25504465041174446	[485,356]	[420,348]	3	hSpCas9	negative selection	4400478
128537404	128537426	5	-	27760321	OCIAML3	viability	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	-0.14847801279535267	[1163,926]	[734,730]	-1	hSpCas9	negative selection	4400479
128537459	128537481	5	+	27760321	OCIAML3	viability	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.41131861875973463	[689,853]	[664,1004]	5	hSpCas9	negative selection	4400480
128338998	128339020	5	-	27760321	OCIAML2	viability	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	0.10335832181683502	[472,488]	[384,465]	1	hSpCas9	negative selection	4483939
128345573	128345595	5	-	27760321	OCIAML2	viability	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.4689187459250463	[399,310]	[336,471]	6	hSpCas9	negative selection	4483940
128349360	128349382	5	+	27760321	OCIAML2	viability	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	0.6733764539289677	[485,356]	[429,681]	8	hSpCas9	negative selection	4483941
128537404	128537426	5	-	27760321	OCIAML2	viability	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	-0.057118535415997984	[1163,926]	[738,898]	0	hSpCas9	negative selection	4483942
128537459	128537481	5	+	27760321	OCIAML2	viability	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.20358379428887918	[689,853]	[631,853]	2	hSpCas9	negative selection	4483943
128338998	128339020	5	-	27760321	MV411	viability	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.7149109178326544	[472,488]	[49,410]	-5	hSpCas9	negative selection	4567402
128345573	128345595	5	-	27760321	MV411	viability	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	-0.7747723508314598	[399,310]	[84,212]	-5	hSpCas9	negative selection	4567403
128349360	128349382	5	+	27760321	MV411	viability	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	0.7216282509558941	[485,356]	[240,774]	5	hSpCas9	negative selection	4567404
128537404	128537426	5	-	27760321	MV411	viability	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.4624740704370358	[1163,926]	[1099,711]	3	hSpCas9	negative selection	4567405
128537459	128537481	5	+	27760321	MV411	viability	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.5776687591107521	[689,853]	[573,1062]	4	hSpCas9	negative selection	4567406
128338998	128339020	5	-	27760321	HL60	viability	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	0.5933179050315364	[472,488]	[845,329]	7	hSpCas9	negative selection	4650865
128345573	128345595	5	-	27760321	HL60	viability	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	-0.03610391263953344	[399,310]	[338,219]	0	hSpCas9	negative selection	4650866
128349360	128349382	5	+	27760321	HL60	viability	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	1.4110114835695535	[485,356]	[910,902]	9	hSpCas9	negative selection	4650867
128537404	128537426	5	-	27760321	HL60	viability	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	-0.4913328600002922	[1163,926]	[483,730]	-5	hSpCas9	negative selection	4650868
128537459	128537481	5	+	27760321	HL60	viability	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.09018756208176548	[689,853]	[674,683]	1	hSpCas9	negative selection	4650869
128338998	128339020	5	-	27760321	HT1080	viability	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	0.9166563727960647	[488,381]	[327,326]	5	hSpCas9	negative selection	4734328
128345573	128345595	5	-	27760321	HT1080	viability	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.4602795806813529	[310,242]	[221,74]	2	hSpCas9	negative selection	4734329
128349360	128349382	5	+	27760321	HT1080	viability	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	1.8701384538030699	[356,278]	[402,528]	8	hSpCas9	negative selection	4734330
128537404	128537426	5	-	27760321	HT1080	viability	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.33457937898711854	[926,723]	[260,582]	1	hSpCas9	negative selection	4734331
128537459	128537481	5	+	27760321	HT1080	viability	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.6503920174050335	[853,666]	[328,635]	3	hSpCas9	negative selection	4734332
128338998	128339020	5	-	27760321	HT29	viability after 7 days	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.1323039006090306	[488,381]	[454,431,632]	-2	hSpCas9	negative selection	4817791
128345573	128345595	5	-	27760321	HT29	viability after 7 days	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.5591751432630103	[310,242]	[688,509,401]	8	hSpCas9	negative selection	4817792
128349360	128349382	5	+	27760321	HT29	viability after 7 days	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	0.5384082268504273	[356,278]	[522,665,581]	7	hSpCas9	negative selection	4817793
128537404	128537426	5	-	27760321	HT29	viability after 7 days	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.363368298914152	[926,723]	[1058,1893,1105]	5	hSpCas9	negative selection	4817794
128537459	128537481	5	+	27760321	HT29	viability after 7 days	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.35554503394863635	[853,666]	[1586,980,1231]	5	hSpCas9	negative selection	4817795
128338998	128339020	5	-	27760321	HT29	viability after 25 days	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	0.1526517591442167	[488,381]	[413,508,766]	1	hSpCas9	negative selection	4901254
128345573	128345595	5	-	27760321	HT29	viability after 25 days	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.5096295753438326	[310,242]	[341,507,514]	5	hSpCas9	negative selection	4901255
128349360	128349382	5	+	27760321	HT29	viability after 25 days	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	1.0247554286404448	[356,278]	[766,670,781]	9	hSpCas9	negative selection	4901256
128537404	128537426	5	-	27760321	HT29	viability after 25 days	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.13491123801164284	[926,723]	[1192,1050,830]	1	hSpCas9	negative selection	4901257
128537459	128537481	5	+	27760321	HT29	viability after 25 days	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.3768937401433765	[853,666]	[1022,1237,1129]	4	hSpCas9	negative selection	4901258
128338998	128339020	5	-	27760321	HT29	viability after 22 days	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.46455707291077003	[488,381]	[239,386,471]	-4	hSpCas9	negative selection	4984717
128345573	128345595	5	-	27760321	HT29	viability after 22 days	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.17644622821906097	[310,242]	[265,283,539]	1	hSpCas9	negative selection	4984718
128349360	128349382	5	+	27760321	HT29	viability after 22 days	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	1.045936253597359	[356,278]	[1098,626,539]	9	hSpCas9	negative selection	4984719
128537404	128537426	5	-	27760321	HT29	viability after 22 days	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.22658795953683764	[926,723]	[1294,1259,786]	2	hSpCas9	negative selection	4984720
128537459	128537481	5	+	27760321	HT29	viability after 22 days	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.32575418859702965	[853,666]	[1058,1033,1214]	3	hSpCas9	negative selection	4984721
128338998	128339020	5	-	27760321	HT29	viability after 19 days	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.19758272211348127	[488,381]	[418,175,695]	-2	hSpCas9	negative selection	5068180
128345573	128345595	5	-	27760321	HT29	viability after 19 days	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	-0.25191375368196056	[310,242]	[449,147,220]	-2	hSpCas9	negative selection	5068181
128349360	128349382	5	+	27760321	HT29	viability after 19 days	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	1.2261871539339995	[356,278]	[843,1085,629]	9	hSpCas9	negative selection	5068182
128537404	128537426	5	-	27760321	HT29	viability after 19 days	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.685288167411483	[926,723]	[1355,975,2178]	7	hSpCas9	negative selection	5068183
128537459	128537481	5	+	27760321	HT29	viability after 19 days	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.41164761313332865	[853,666]	[1257,1230,997]	4	hSpCas9	negative selection	5068184
128338998	128339020	5	-	27760321	HT29	viability after 16 days	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.5579165436352982	[488,381]	[501,333,172]	-5	hSpCas9	negative selection	5151643
128345573	128345595	5	-	27760321	HT29	viability after 16 days	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.4303912707821139	[310,242]	[460,264,534]	5	hSpCas9	negative selection	5151644
128349360	128349382	5	+	27760321	HT29	viability after 16 days	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	0.6307802786339128	[356,278]	[657,467,538]	7	hSpCas9	negative selection	5151645
128537404	128537426	5	-	27760321	HT29	viability after 16 days	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.18899763802242497	[926,723]	[1303,831,1051]	2	hSpCas9	negative selection	5151646
128537459	128537481	5	+	27760321	HT29	viability after 16 days	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.23398137419315246	[853,666]	[1047,1208,743]	2	hSpCas9	negative selection	5151647
128338998	128339020	5	-	27760321	HT29	viability after 13 days	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.5551789333924791	[488,381]	[218,437,372]	-6	hSpCas9	negative selection	5235106
128345573	128345595	5	-	27760321	HT29	viability after 13 days	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.21991792138102695	[310,242]	[223,436,456]	2	hSpCas9	negative selection	5235107
128349360	128349382	5	+	27760321	HT29	viability after 13 days	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	0.6599001031598609	[356,278]	[674,465,605]	8	hSpCas9	negative selection	5235108
128537404	128537426	5	-	27760321	HT29	viability after 13 days	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.25393594613077375	[926,723]	[1023,1359,1047]	3	hSpCas9	negative selection	5235109
128537459	128537481	5	+	27760321	HT29	viability after 13 days	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.3448599673342303	[853,666]	[1439,924,1002]	4	hSpCas9	negative selection	5235110
128338998	128339020	5	-	27760321	HT29	viability after 10 days	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.2868770049572387	[488,381]	[565,309,456]	-4	hSpCas9	negative selection	5318569
128345573	128345595	5	-	27760321	HT29	viability after 10 days	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	0.04036833926268957	[310,242]	[280,408,377]	0	hSpCas9	negative selection	5318570
128349360	128349382	5	+	27760321	HT29	viability after 10 days	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	0.6417933120381386	[356,278]	[684,659,516]	8	hSpCas9	negative selection	5318571
128537404	128537426	5	-	27760321	HT29	viability after 10 days	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.11495556840226784	[926,723]	[1103,971,1264]	1	hSpCas9	negative selection	5318572
128537459	128537481	5	+	27760321	HT29	viability after 10 days	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.22652845668829724	[853,666]	[1520,1110,709]	3	hSpCas9	negative selection	5318573
128338998	128339020	5	-	27760321	MOLM13	viability	GAATCTGCGTCAATACACCGGG	FBN2	ENSG00000138829	-0.21013512254493044	[472,488]	[286,191]	-1	hSpCas9	negative selection	5402032
128345573	128345595	5	-	27760321	MOLM13	viability	CTCGGTGTAGATATTCGCATGG	FBN2	ENSG00000138829	-0.14689713128482967	[399,310]	[288,86]	-1	hSpCas9	negative selection	5402033
128349360	128349382	5	+	27760321	MOLM13	viability	GCCAGTCCCATCCAACGTAAGG	FBN2	ENSG00000138829	1.0938335608141891	[485,356]	[470,529]	7	hSpCas9	negative selection	5402034
128537404	128537426	5	-	27760321	MOLM13	viability	CGCCCGAGTATCGCGAGGAGGG	FBN2	ENSG00000138829	0.40549041706984146	[1163,926]	[1124,479]	3	hSpCas9	negative selection	5402035
128537459	128537481	5	+	27760321	MOLM13	viability	ACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.736115266472922	[689,853]	[764,707]	5	hSpCas9	negative selection	5402036
128537806	128537829	5	-	27661255	K562	viability	GCCGCTCACTGCGCTAGACCCGG	FBN2	ENSG00000138829	0.41925536492859106	[112,132]	[130,130]	9	dCas9-KRAB	negative selection	5479612
128537408	128537431	5	-	27260156	BXPC3	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.059309549258088096	[437]	[394,379,454,546]	-1	hSpCas9	negative selection	5543107
128537400	128537423	5	+	27260156	BXPC3	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.2784162120232882	[634]	[806,906,768,713]	6	hSpCas9	negative selection	5543108
128536470	128536493	5	-	27260156	BXPC3	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.4023626593210561	[550]	[676,787,657,945]	8	hSpCas9	negative selection	5543109
128536393	128536416	5	+	27260156	BXPC3	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.04306927537044092	[413]	[352,418,438,481]	-1	hSpCas9	negative selection	5607371
128527909	128527932	5	+	27260156	BXPC3	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.07862693191787695	[385]	[542,521,342,251]	1	hSpCas9	negative selection	5607372
128527884	128527907	5	+	27260156	BXPC3	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.3382440924489496	[839]	[922,965,1247,1358]	7	hSpCas9	negative selection	5607373
128537408	128537431	5	-	27260156	A673	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.05342144530083898	[437]	[526,384,549,572]	-1	hSpCas9	negative selection	5664358
128537400	128537423	5	+	27260156	A673	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.11243162678732227	[634]	[962,685,824,841]	2	hSpCas9	negative selection	5664359
128536470	128536493	5	-	27260156	A673	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.5048251889862044	[550]	[1012,858,934,957]	9	hSpCas9	negative selection	5664360
128536393	128536416	5	+	27260156	A673	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.13583134347371484	[413]	[469,411,428,503]	-3	hSpCas9	negative selection	5728622
128527909	128527932	5	+	27260156	A673	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.20748214614836535	[385]	[490,296,407,422]	-5	hSpCas9	negative selection	5728623
128527884	128527907	5	+	27260156	A673	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.2640686505528864	[839]	[1285,1076,1219,1274]	6	hSpCas9	negative selection	5728624
128537408	128537431	5	-	27260156	A375	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.16525469501328974	[437]	[614,701,543,462]	2	hSpCas9	negative selection	5785609
128537400	128537423	5	+	27260156	A375	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.2720353639680066	[634]	[630,1425,913,702]	4	hSpCas9	negative selection	5785610
128536470	128536493	5	-	27260156	A375	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.6362691836040775	[550]	[734,1186,1040,1051]	8	hSpCas9	negative selection	5785611
128536393	128536416	5	+	27260156	A375	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.5218341255328522	[413]	[336,326,283,389]	-6	hSpCas9	negative selection	5849873
128527909	128527932	5	+	27260156	A375	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.15494915835610884	[385]	[394,473,365,393]	-2	hSpCas9	negative selection	5849874
128527884	128527907	5	+	27260156	A375	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.6656335126757646	[839]	[1451,1662,1633,1491]	8	hSpCas9	negative selection	5849875
128537408	128537431	5	-	27260156	COLO741	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.0980058539558688	[437]	[571,728,499]	2	hSpCas9	negative selection	5906860
128537400	128537423	5	+	27260156	COLO741	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	-0.05596970825864922	[634]	[819,840,688]	-1	hSpCas9	negative selection	5906861
128536470	128536493	5	-	27260156	COLO741	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.310769033299906	[550]	[894,954,776]	6	hSpCas9	negative selection	5906862
128536393	128536416	5	+	27260156	COLO741	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.09268934881695255	[413]	[588,706,408]	2	hSpCas9	negative selection	5971124
128527909	128527932	5	+	27260156	COLO741	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.42965752849284733	[385]	[498,289,322]	-7	hSpCas9	negative selection	5971125
128527884	128527907	5	+	27260156	COLO741	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.3142418762474113	[839]	[1216,1582,1200]	6	hSpCas9	negative selection	5971126
128537408	128537431	5	-	27260156	CAL120	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.29627776307775977	[437]	[678,600,727]	4	hSpCas9	negative selection	6028111
128537400	128537423	5	+	27260156	CAL120	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.8671839744599814	[634]	[829,2264,1141]	9	hSpCas9	negative selection	6028112
128536470	128536493	5	-	27260156	CAL120	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.9278307958727614	[550]	[1185,1188,1515]	9	hSpCas9	negative selection	6028113
128536393	128536416	5	+	27260156	CAL120	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.13967621407352393	[413]	[460,376,561]	-2	hSpCas9	negative selection	6092375
128527909	128527932	5	+	27260156	CAL120	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.10529634490141615	[385]	[668,320,383]	-1	hSpCas9	negative selection	6092376
128527884	128527907	5	+	27260156	CAL120	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.44868992449861245	[839]	[1865,1089,1389]	6	hSpCas9	negative selection	6092377
128537408	128537431	5	-	27260156	CADOES1	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.21504547305557814	[437]	[304,318,373,407]	-4	hSpCas9	negative selection	6149362
128537400	128537423	5	+	27260156	CADOES1	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.21068935704851816	[634]	[697,708,689,634]	3	hSpCas9	negative selection	6149363
128536470	128536493	5	-	27260156	CADOES1	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.42405414761215676	[550]	[726,544,658,823]	7	hSpCas9	negative selection	6149364
128536393	128536416	5	+	27260156	CADOES1	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.07304129691244261	[413]	[405,203,494,518]	1	hSpCas9	negative selection	6213626
128527909	128527932	5	+	27260156	CADOES1	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.27609708553155554	[385]	[358,210,332,281]	-5	hSpCas9	negative selection	6213627
128527884	128527907	5	+	27260156	CADOES1	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.5262547729042604	[839]	[1272,904,1214,1105]	8	hSpCas9	negative selection	6213628
128537408	128537431	5	-	27260156	EWS502	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.10678642797704335	[437]	[445,489,554,513]	1	hSpCas9	negative selection	6270613
128537400	128537423	5	+	27260156	EWS502	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.40468010586531117	[634]	[895,1033,827,784]	7	hSpCas9	negative selection	6270614
128536470	128536493	5	-	27260156	EWS502	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.37178876934579796	[550]	[463,888,928,768]	6	hSpCas9	negative selection	6270615
128536393	128536416	5	+	27260156	EWS502	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.18614847455474842	[413]	[382,420,260,478]	-3	hSpCas9	negative selection	6334877
128527909	128527932	5	+	27260156	EWS502	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.24546181308944148	[385]	[291,420,261,409]	-4	hSpCas9	negative selection	6334878
128527884	128527907	5	+	27260156	EWS502	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.5829807725135829	[839]	[1129,1556,1289,1365]	8	hSpCas9	negative selection	6334879
128537408	128537431	5	-	27260156	EW8	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.14398774625688718	[437]	[461,309,493,291]	2	hSpCas9	negative selection	6391864
128537400	128537423	5	+	27260156	EW8	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.15325378760308478	[634]	[789,557,481,496]	3	hSpCas9	negative selection	6391865
128536470	128536493	5	-	27260156	EW8	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.48767519884727617	[550]	[699,662,525,638]	8	hSpCas9	negative selection	6391866
128536393	128536416	5	+	27260156	EW8	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.12199416063930585	[413]	[358,294,253,338]	-2	hSpCas9	negative selection	6456128
128527909	128527932	5	+	27260156	EW8	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.12016162898584903	[385]	[223,260,221,446]	-2	hSpCas9	negative selection	6456129
128527884	128527907	5	+	27260156	EW8	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.4308451719771731	[839]	[869,890,811,1106]	7	hSpCas9	negative selection	6456130
128537408	128537431	5	-	27260156	CORL105	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.061141827655675496	[437]	[510,446,696,510]	1	hSpCas9	negative selection	6513115
128537400	128537423	5	+	27260156	CORL105	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.33152766499915115	[634]	[738,891,1000,1112]	6	hSpCas9	negative selection	6513116
128536470	128536493	5	-	27260156	CORL105	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.7510682987153936	[550]	[1028,906,1230,1198]	9	hSpCas9	negative selection	6513117
128536393	128536416	5	+	27260156	CORL105	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.32959685958896695	[413]	[288,463,537,270]	-6	hSpCas9	negative selection	6577379
128527909	128527932	5	+	27260156	CORL105	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.2798231654337975	[385]	[401,236,409,448]	-5	hSpCas9	negative selection	6577380
128527884	128527907	5	+	27260156	CORL105	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.24465184656065553	[839]	[1007,972,1727,1037]	4	hSpCas9	negative selection	6577381
128537408	128537431	5	-	27260156	HS294T	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.1321093640961594	[437]	[243,159,166,161]	1	hSpCas9	negative selection	6634366
128537400	128537423	5	+	27260156	HS294T	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	1.1689822816081887	[634]	[364,681,776,364]	9	hSpCas9	negative selection	6634367
128536470	128536493	5	-	27260156	HS294T	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.17014752079428927	[550]	[198,226,243,302]	2	hSpCas9	negative selection	6634368
128536393	128536416	5	+	27260156	HS294T	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.11473728150943024	[413]	[221,117,119,119]	-2	hSpCas9	negative selection	6698630
128527909	128527932	5	+	27260156	HS294T	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.10446959608445172	[385]	[104,216,150,173]	1	hSpCas9	negative selection	6698631
128527884	128527907	5	+	27260156	HS294T	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.3404074470351295	[839]	[496,369,315,461]	4	hSpCas9	negative selection	6698632
128537408	128537431	5	-	27260156	HCC44	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.4668305282576359	[437]	[446,260,303,428]	-6	hSpCas9	negative selection	6755617
128537400	128537423	5	+	27260156	HCC44	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	-0.029012576207666008	[634]	[851,628,905,488]	0	hSpCas9	negative selection	6755618
128536470	128536493	5	-	27260156	HCC44	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.4930830839994068	[550]	[1142,682,1142,637]	7	hSpCas9	negative selection	6755619
128536393	128536416	5	+	27260156	HCC44	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.07028697610122503	[413]	[299,480,375,587]	-1	hSpCas9	negative selection	6819881
128527909	128527932	5	+	27260156	HCC44	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.11208149232386877	[385]	[453,406,447,317]	-2	hSpCas9	negative selection	6819882
128527884	128527907	5	+	27260156	HCC44	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.5384182923504675	[839]	[1561,1363,1239,1337]	8	hSpCas9	negative selection	6819883
128537408	128537431	5	-	27260156	G402	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.24175796515247372	[437]	[614,290,432,479]	-3	hSpCas9	negative selection	6876868
128537400	128537423	5	+	27260156	G402	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.5222262914389604	[634]	[1331,859,1078,1188]	6	hSpCas9	negative selection	6876869
128536470	128536493	5	-	27260156	G402	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.5317817286761297	[550]	[1062,674,1040,1094]	6	hSpCas9	negative selection	6876870
128536393	128536416	5	+	27260156	G402	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.10775856974683318	[413]	[661,233,508,481]	-1	hSpCas9	negative selection	6941132
128527909	128527932	5	+	27260156	G402	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.8734676748710577	[385]	[367,278,338,67]	-8	hSpCas9	negative selection	6941133
128527884	128527907	5	+	27260156	G402	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.8393633548512884	[839]	[2578,1898,1869,1126]	9	hSpCas9	negative selection	6941134
128537408	128537431	5	-	27260156	L33	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.3302801028299582	[437]	[520,248,388,456]	7	hSpCas9	negative selection	6998119
128537400	128537423	5	+	27260156	L33	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.24121852218820022	[634]	[829,284,543,610]	5	hSpCas9	negative selection	6998120
128536470	128536493	5	-	27260156	L33	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.5712430379039716	[550]	[891,299,458,916]	9	hSpCas9	negative selection	6998121
128536393	128536416	5	+	27260156	L33	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.37471852489994856	[413]	[221,165,215,308]	-7	hSpCas9	negative selection	7062383
128527909	128527932	5	+	27260156	L33	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.04444841006043862	[385]	[345,198,241,376]	1	hSpCas9	negative selection	7062384
128527884	128527907	5	+	27260156	L33	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.17106302299711773	[839]	[991,417,515,947]	4	hSpCas9	negative selection	7062385
128537408	128537431	5	-	27260156	K562	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.11976761417837642	[437]	[186,459,871,179]	1	hSpCas9	negative selection	7119370
128537400	128537423	5	+	27260156	K562	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	-0.12806789476182312	[634]	[600,507,451,506]	-2	hSpCas9	negative selection	7119371
128536470	128536493	5	-	27260156	K562	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.4030157635969308	[550]	[807,633,497,654]	5	hSpCas9	negative selection	7119372
128536393	128536416	5	+	27260156	K562	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.7923274911035727	[413]	[235,223,175,213]	-7	hSpCas9	negative selection	7183634
128527909	128527932	5	+	27260156	K562	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.05539455316166311	[385]	[269,436,445,275]	0	hSpCas9	negative selection	7183635
128527884	128527907	5	+	27260156	K562	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.7255493662543586	[839]	[1161,1245,1457,1072]	8	hSpCas9	negative selection	7183636
128537408	128537431	5	-	27260156	HT29	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.0015170992464413197	[437]	[795,480,424,451]	0	hSpCas9	negative selection	7240621
128537400	128537423	5	+	27260156	HT29	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.2348936648106827	[634]	[959,1150,822,738]	4	hSpCas9	negative selection	7240622
128536470	128536493	5	-	27260156	HT29	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.46308607991898965	[550]	[997,837,1006,850]	8	hSpCas9	negative selection	7240623
128536393	128536416	5	+	27260156	HT29	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.18750835485071055	[413]	[459,419,504,385]	-4	hSpCas9	negative selection	7304885
128527909	128527932	5	+	27260156	HT29	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.08379487815193692	[385]	[305,539,327,574]	-2	hSpCas9	negative selection	7304886
128527884	128527907	5	+	27260156	HT29	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.5637783902576625	[839]	[1534,1621,1326,1548]	9	hSpCas9	negative selection	7304887
128537408	128537431	5	-	27260156	MHHES1	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.16292061338742111	[437]	[550,587,571,500]	3	hSpCas9	negative selection	7361872
128537400	128537423	5	+	27260156	MHHES1	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.30254069829091196	[634]	[703,817,1092,868]	5	hSpCas9	negative selection	7361873
128536470	128536493	5	-	27260156	MHHES1	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.2929081765853475	[550]	[822,961,743,567]	5	hSpCas9	negative selection	7361874
128536393	128536416	5	+	27260156	MHHES1	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.10880275727765848	[413]	[466,517,371,385]	-2	hSpCas9	negative selection	7426136
128527909	128527932	5	+	27260156	MHHES1	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.3841027805933026	[385]	[300,393,395,254]	-6	hSpCas9	negative selection	7426137
128527884	128527907	5	+	27260156	MHHES1	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.5926324113902346	[839]	[1769,1337,1416,1227]	8	hSpCas9	negative selection	7426138
128537408	128537431	5	-	27260156	MEWO	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.004163075122261953	[437]	[627,244,395]	0	hSpCas9	negative selection	7483123
128537400	128537423	5	+	27260156	MEWO	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.067478166951842	[634]	[572,591,692]	1	hSpCas9	negative selection	7483124
128536470	128536493	5	-	27260156	MEWO	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.4833687896472575	[550]	[809,748,619]	8	hSpCas9	negative selection	7483125
128536393	128536416	5	+	27260156	MEWO	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.17637453152589402	[413]	[541,269,521]	4	hSpCas9	negative selection	7547387
128527909	128527932	5	+	27260156	MEWO	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.013513537992424718	[385]	[309,346,406]	0	hSpCas9	negative selection	7547388
128527884	128527907	5	+	27260156	MEWO	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.27813375052863454	[839]	[1171,773,955]	6	hSpCas9	negative selection	7547389
128537408	128537431	5	-	27260156	LNCAPCLONEFGC	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.01460630005510681	[437]	[342,469,437,353]	0	hSpCas9	negative selection	7604374
128537400	128537423	5	+	27260156	LNCAPCLONEFGC	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.17761481603085355	[634]	[782,519,677,630]	2	hSpCas9	negative selection	7604375
128536470	128536493	5	-	27260156	LNCAPCLONEFGC	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.42329930602961063	[550]	[677,487,893,661]	6	hSpCas9	negative selection	7604376
128536393	128536416	5	+	27260156	LNCAPCLONEFGC	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.2666158574783926	[413]	[302,254,360,338]	-4	hSpCas9	negative selection	7668638
128527909	128527932	5	+	27260156	LNCAPCLONEFGC	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.4886761269586276	[385]	[234,220,324,228]	-6	hSpCas9	negative selection	7668639
128527884	128527907	5	+	27260156	LNCAPCLONEFGC	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.5632818746181356	[839]	[1198,1059,1336,934]	8	hSpCas9	negative selection	7668640
128537408	128537431	5	-	27260156	PANC0327	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.24551996639748175	[437]	[461,457,721,203]	3	hSpCas9	negative selection	7725625
128537400	128537423	5	+	27260156	PANC0327	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.5255300925481143	[634]	[522,748,884,1074]	7	hSpCas9	negative selection	7725626
128536470	128536493	5	-	27260156	PANC0327	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.5147969885071326	[550]	[611,821,628,710]	7	hSpCas9	negative selection	7725627
128536393	128536416	5	+	27260156	PANC0327	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.00044410455596971543	[413]	[477,159,265,601]	0	hSpCas9	negative selection	7789889
128527909	128527932	5	+	27260156	PANC0327	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.49275677360758396	[385]	[251,190,206,331]	-6	hSpCas9	negative selection	7789890
128527884	128527907	5	+	27260156	PANC0327	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.16470631966650529	[839]	[1234,551,896,730]	2	hSpCas9	negative selection	7789891
128537408	128537431	5	-	27260156	NCIH2009	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.26741057770942994	[437]	[856,696,678]	3	hSpCas9	negative selection	7846876
128537400	128537423	5	+	27260156	NCIH2009	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.6899647971309211	[634]	[1554,1475,1283]	8	hSpCas9	negative selection	7846877
128536470	128536493	5	-	27260156	NCIH2009	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.7595705002267016	[550]	[1447,1376,1109]	9	hSpCas9	negative selection	7846878
128536393	128536416	5	+	27260156	NCIH2009	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.2854458700789206	[413]	[466,499,453]	-4	hSpCas9	negative selection	7911140
128527909	128527932	5	+	27260156	NCIH2009	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.07518683830476786	[385]	[573,548,581]	1	hSpCas9	negative selection	7911141
128527884	128527907	5	+	27260156	NCIH2009	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.4544834564394893	[839]	[1540,1583,1683]	6	hSpCas9	negative selection	7911142
128537408	128537431	5	-	27260156	NCIH1373	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.09809838015506771	[437]	[977,218,453,145]	1	hSpCas9	negative selection	7968127
128537400	128537423	5	+	27260156	NCIH1373	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.9003758128027601	[634]	[1757,608,1156,517]	8	hSpCas9	negative selection	7968128
128536470	128536493	5	-	27260156	NCIH1373	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.06903620934867036	[550]	[654,644,519,204]	0	hSpCas9	negative selection	7968129
128536393	128536416	5	+	27260156	NCIH1373	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.8306019136471465	[413]	[289,172,437,37]	-7	hSpCas9	negative selection	8032391
128527909	128527932	5	+	27260156	NCIH1373	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.061673646174243424	[385]	[297,268,844,57]	0	hSpCas9	negative selection	8032392
128527884	128527907	5	+	27260156	NCIH1373	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.7023199636348665	[839]	[1643,1348,1407,465]	7	hSpCas9	negative selection	8032393
128537408	128537431	5	-	27260156	PATU8902	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.6405449656998587	[437]	[551,499,316,185]	-6	hSpCas9	negative selection	8089378
128537400	128537423	5	+	27260156	PATU8902	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.262472389957318	[634]	[1167,1032,791,1343]	2	hSpCas9	negative selection	8089379
128536470	128536493	5	-	27260156	PATU8902	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.4065749249026377	[550]	[1464,1010,693,961]	4	hSpCas9	negative selection	8089380
128536393	128536416	5	+	27260156	PATU8902	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.39285399882309896	[413]	[363,362,380,690]	-4	hSpCas9	negative selection	8153642
128527909	128527932	5	+	27260156	PATU8902	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.9172934762063647	[385]	[241,127,451,268]	-7	hSpCas9	negative selection	8153643
128527884	128527907	5	+	27260156	PATU8902	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.6738675146962354	[839]	[2277,1665,1243,2492]	7	hSpCas9	negative selection	8153644
128537408	128537431	5	-	27260156	PANC1	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.07947542373016034	[437]	[294,462,493,354]	1	hSpCas9	negative selection	8210629
128537400	128537423	5	+	27260156	PANC1	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.4409134078059181	[634]	[722,973,400,873]	7	hSpCas9	negative selection	8210630
128536470	128536493	5	-	27260156	PANC1	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.411828799155311	[550]	[597,680,795,471]	6	hSpCas9	negative selection	8210631
128536393	128536416	5	+	27260156	PANC1	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.10015553342222183	[413]	[156,461,483,261]	-2	hSpCas9	negative selection	8274893
128527909	128527932	5	+	27260156	PANC1	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.01044386304507966	[385]	[325,310,291,370]	0	hSpCas9	negative selection	8274894
128527884	128527907	5	+	27260156	PANC1	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.41381983201484096	[839]	[908,1046,949,943]	6	hSpCas9	negative selection	8274895
128537408	128537431	5	-	27260156	PANC0813	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.03192826934809065	[437]	[688,670,355,407]	0	hSpCas9	negative selection	8331880
128537400	128537423	5	+	27260156	PANC0813	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.4551211263139138	[634]	[1153,911,1137,903]	7	hSpCas9	negative selection	8331881
128536470	128536493	5	-	27260156	PANC0813	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.7038412517132271	[550]	[976,1222,1048,963]	9	hSpCas9	negative selection	8331882
128536393	128536416	5	+	27260156	PANC0813	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.13295864368472982	[413]	[344,358,668,394]	-2	hSpCas9	negative selection	8396144
128527909	128527932	5	+	27260156	PANC0813	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.10008182551894679	[385]	[439,488,485,285]	-2	hSpCas9	negative selection	8396145
128527884	128527907	5	+	27260156	PANC0813	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.3599763813025738	[839]	[1248,1328,1416,1077]	6	hSpCas9	negative selection	8396146
128537408	128537431	5	-	27260156	RDES	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.05576408666302745	[437]	[397,443,785,490]	0	hSpCas9	negative selection	8453131
128537400	128537423	5	+	27260156	RDES	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.2218997789312051	[634]	[751,993,766,872]	3	hSpCas9	negative selection	8453132
128536470	128536493	5	-	27260156	RDES	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.40615755352552396	[550]	[636,802,1000,965]	6	hSpCas9	negative selection	8453133
128536393	128536416	5	+	27260156	RDES	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.18978474015377794	[413]	[424,390,445,390]	-3	hSpCas9	negative selection	8517395
128527909	128527932	5	+	27260156	RDES	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.22746738143121736	[385]	[312,396,489,310]	-4	hSpCas9	negative selection	8517396
128527884	128527907	5	+	27260156	RDES	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.6798986202009747	[839]	[1099,1545,1569,2114]	9	hSpCas9	negative selection	8517397
128537408	128537431	5	-	27260156	PC3	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.17175432181235867	[437]	[296,508,837,495]	4	hSpCas9	negative selection	8574382
128537400	128537423	5	+	27260156	PC3	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	-0.060963003991071796	[634]	[325,641,634,916]	-1	hSpCas9	negative selection	8574383
128536470	128536493	5	-	27260156	PC3	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.4141995230000217	[550]	[524,860,988,649]	8	hSpCas9	negative selection	8574384
128536393	128536416	5	+	27260156	PC3	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.2047533296767035	[413]	[132,302,796,454]	-4	hSpCas9	negative selection	8638646
128527909	128527932	5	+	27260156	PC3	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.20754914220880166	[385]	[214,376,434,361]	-5	hSpCas9	negative selection	8638647
128527884	128527907	5	+	27260156	PC3	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.5099606046989329	[839]	[820,1218,1785,1208]	9	hSpCas9	negative selection	8638648
128537408	128537431	5	-	27260156	PATU8988T	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	0.21035184040208352	[437]	[453,664,374,481]	3	hSpCas9	negative selection	8695633
128537400	128537423	5	+	27260156	PATU8988T	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.39629550448543865	[634]	[724,815,899,786]	6	hSpCas9	negative selection	8695634
128536470	128536493	5	-	27260156	PATU8988T	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.3282486903673565	[550]	[649,799,660,566]	5	hSpCas9	negative selection	8695635
128536393	128536416	5	+	27260156	PATU8988T	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.11374823215244995	[413]	[449,135,529,335]	-2	hSpCas9	negative selection	8759897
128527909	128527932	5	+	27260156	PATU8988T	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.5209174469338184	[385]	[671,301,479,676]	8	hSpCas9	negative selection	8759898
128527884	128527907	5	+	27260156	PATU8988T	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.05075303318483726	[839]	[887,897,816,758]	0	hSpCas9	negative selection	8759899
128537408	128537431	5	-	27260156	T47D	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.06753882127981523	[437]	[494,416,484,558]	-1	hSpCas9	negative selection	8816884
128537400	128537423	5	+	27260156	T47D	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.19587312677427487	[634]	[867,856,852,808]	4	hSpCas9	negative selection	8816885
128536470	128536493	5	-	27260156	T47D	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.5068160217328153	[550]	[842,971,904,922]	9	hSpCas9	negative selection	8816886
128536393	128536416	5	+	27260156	T47D	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.2754735316709919	[413]	[506,432,324,324]	-6	hSpCas9	negative selection	8881148
128527909	128527932	5	+	27260156	T47D	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.21736683130470735	[385]	[400,366,407,371]	-5	hSpCas9	negative selection	8881149
128527884	128527907	5	+	27260156	T47D	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.36550173636870076	[839]	[1277,1165,1294,1312]	7	hSpCas9	negative selection	8881150
128537408	128537431	5	-	27260156	SU8686	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.07909610399844891	[437]	[385,451,364,438]	-1	hSpCas9	negative selection	8938135
128537400	128537423	5	+	27260156	SU8686	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.637140593055709	[634]	[769,892,1059,1270]	9	hSpCas9	negative selection	8938136
128536470	128536493	5	-	27260156	SU8686	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.5947108642318528	[550]	[837,751,791,936]	8	hSpCas9	negative selection	8938137
128536393	128536416	5	+	27260156	SU8686	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.3964441849239198	[413]	[265,272,381,340]	-6	hSpCas9	negative selection	9002399
128527909	128527932	5	+	27260156	SU8686	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.33452141831191196	[385]	[286,308,214,417]	-5	hSpCas9	negative selection	9002400
128527884	128527907	5	+	27260156	SU8686	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.4289459567312086	[839]	[1174,1056,1028,1232]	7	hSpCas9	negative selection	9002401
128537408	128537431	5	-	27260156	SKES1	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.26707560110830264	[437]	[353,491,398,232]	-5	hSpCas9	negative selection	9059386
128537400	128537423	5	+	27260156	SKES1	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	-0.06887914517805027	[634]	[666,671,570,525]	-1	hSpCas9	negative selection	9059387
128536470	128536493	5	-	27260156	SKES1	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.3341285502642607	[550]	[751,753,517,750]	7	hSpCas9	negative selection	9059388
128536393	128536416	5	+	27260156	SKES1	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.22057896232744068	[413]	[213,364,405,403]	-5	hSpCas9	negative selection	9123650
128527909	128527932	5	+	27260156	SKES1	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.01553489564013405	[385]	[585,383,402,225]	0	hSpCas9	negative selection	9123651
128527884	128527907	5	+	27260156	SKES1	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.14928191734059348	[839]	[883,1311,905,675]	3	hSpCas9	negative selection	9123652
128537408	128537431	5	-	27260156	TOV112D	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.29245145742090173	[437]	[448,278,358,333]	-5	hSpCas9	negative selection	9180637
128537400	128537423	5	+	27260156	TOV112D	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.3090976877566534	[634]	[769,1032,753,655]	6	hSpCas9	negative selection	9180638
128536470	128536493	5	-	27260156	TOV112D	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.2422407485601856	[550]	[588,803,531,714]	4	hSpCas9	negative selection	9180639
128536393	128536416	5	+	27260156	TOV112D	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.2107647152030252	[413]	[294,333,497,295]	-4	hSpCas9	negative selection	9244901
128527909	128527932	5	+	27260156	TOV112D	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.09551544090158687	[385]	[388,574,370,355]	1	hSpCas9	negative selection	9244902
128527884	128527907	5	+	27260156	TOV112D	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.4601703721995787	[839]	[1076,1349,1219,1024]	8	hSpCas9	negative selection	9244903
128537408	128537431	5	-	27260156	TC71	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.09535981445048439	[437]	[475,471,314,501]	-2	hSpCas9	negative selection	9301888
128537400	128537423	5	+	27260156	TC71	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	0.07956891236182678	[634]	[691,765,792,617]	2	hSpCas9	negative selection	9301889
128536470	128536493	5	-	27260156	TC71	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.4160961029643472	[550]	[753,761,758,884]	8	hSpCas9	negative selection	9301890
128536393	128536416	5	+	27260156	TC71	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.04823513331416515	[413]	[411,505,331,472]	-1	hSpCas9	negative selection	9366152
128527909	128527932	5	+	27260156	TC71	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.05789416041625234	[385]	[315,381,379,521]	-1	hSpCas9	negative selection	9366153
128527884	128527907	5	+	27260156	TC71	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.33693534506732226	[839]	[1162,1134,1136,1111]	7	hSpCas9	negative selection	9366154
128537408	128537431	5	-	27260156	TC32	viability	TCTAGCGCCCGAGTATCGCGAGG	FBN2	ENSG00000138829	-0.1282540749634609	[437]	[394,247,540,374]	-2	hSpCas9	negative selection	9423139
128537400	128537423	5	+	27260156	TC32	viability	GGCACCCTCCTCGCGATACTCGG	FBN2	ENSG00000138829	-0.005201446530100906	[634]	[671,353,816,621]	0	hSpCas9	negative selection	9423140
128536470	128536493	5	-	27260156	TC32	viability	CATCACAGGCCCAACGTGTGCGG	FBN2	ENSG00000138829	0.45542984744875636	[550]	[677,471,859,920]	7	hSpCas9	negative selection	9423141
128536393	128536416	5	+	27260156	TC32	viability	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.26021446898081024	[413]	[343,216,413,360]	-5	hSpCas9	negative selection	9487403
128527909	128527932	5	+	27260156	TC32	viability	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.28656585762738596	[385]	[272,181,418,370]	-5	hSpCas9	negative selection	9487404
128527884	128527907	5	+	27260156	TC32	viability	AAGTTCCAATATATCCTTTCTGG	FBN2	ENSG00000138829	0.6571820534896429	[839]	[1230,988,1680,1171]	9	hSpCas9	negative selection	9487405
128446502	128446525	5	+	27869803	HPAFII	viability after 27 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.0049649321033914395	[390]	[328,103,NaN]	0	hSpCas9	negative selection	9589785
128519297	128519320	5	+	27869803	HPAFII	viability after 27 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.029803962967493436	[415]	[243,205,NaN]	0	hSpCas9	negative selection	9589786
128527909	128527932	5	+	27869803	HPAFII	viability after 27 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.3818392634522658	[126]	[92,81,NaN]	3	hSpCas9	negative selection	9589787
128530611	128530634	5	+	27869803	HPAFII	viability after 27 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-0.5094833512331398	[47]	[2,29,NaN]	-4	hSpCas9	negative selection	9589788
128536393	128536416	5	+	27869803	HPAFII	viability after 27 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.09763000323820709	[350]	[107,271,NaN]	0	hSpCas9	negative selection	9589789
128537458	128537481	5	+	27869803	HPAFII	viability after 27 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	1.00513755265288	[185]	[198,193,NaN]	8	hSpCas9	negative selection	9589790
128446502	128446525	5	+	27869803	HPAFII	viability after 15 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.05569020879353448	[390]	[481,355,NaN]	0	hSpCas9	negative selection	9672234
128519297	128519320	5	+	27869803	HPAFII	viability after 15 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	-0.19964796831158937	[415]	[466,340,NaN]	-2	hSpCas9	negative selection	9672235
128527909	128527932	5	+	27869803	HPAFII	viability after 15 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.24328367838259168	[126]	[110,192,NaN]	3	hSpCas9	negative selection	9672236
128530611	128530634	5	+	27869803	HPAFII	viability after 15 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-0.2785266359738703	[47]	[7,63,NaN]	-3	hSpCas9	negative selection	9672237
128536393	128536416	5	+	27869803	HPAFII	viability after 15 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.30519100838093144	[350]	[189,376,NaN]	-3	hSpCas9	negative selection	9672238
128537458	128537481	5	+	27869803	HPAFII	viability after 15 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.3862468175348069	[185]	[436,151,NaN]	4	hSpCas9	negative selection	9672239
128446502	128446525	5	+	27869803	ASPC1	viability after 36 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.24720846336543123	[1071]	[607,663,149]	2	hSpCas9	negative selection	9754683
128519297	128519320	5	+	27869803	ASPC1	viability after 36 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.49653974416063185	[820]	[288,591,331]	5	hSpCas9	negative selection	9754684
128527909	128527932	5	+	27869803	ASPC1	viability after 36 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-1.688870296017834	[218]	[0,61,8]	-9	hSpCas9	negative selection	9754685
128530611	128530634	5	+	27869803	ASPC1	viability after 36 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-2.9026187224066544	[155]	[3,17,0]	-9	hSpCas9	negative selection	9754686
128536393	128536416	5	+	27869803	ASPC1	viability after 36 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.020157227263511435	[925]	[414,230,339]	0	hSpCas9	negative selection	9754687
128537458	128537481	5	+	27869803	ASPC1	viability after 36 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.2703868701684387	[535]	[137,169,328]	2	hSpCas9	negative selection	9754688
128446502	128446525	5	+	27869803	PATU8988S	viability after 35 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	-0.2909875413552683	[782]	[148,366,NaN]	-3	hSpCas9	negative selection	9837132
128519297	128519320	5	+	27869803	PATU8988S	viability after 35 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.37633302576740313	[737]	[304,466,NaN]	4	hSpCas9	negative selection	9837133
128527909	128527932	5	+	27869803	PATU8988S	viability after 35 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.24296225084256395	[269]	[42,140,NaN]	-3	hSpCas9	negative selection	9837134
128530611	128530634	5	+	27869803	PATU8988S	viability after 35 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.9384476193377278	[141]	[154,63,NaN]	8	hSpCas9	negative selection	9837135
128536393	128536416	5	+	27869803	PATU8988S	viability after 35 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.40861023771285687	[910]	[235,316,NaN]	-4	hSpCas9	negative selection	9837136
128537458	128537481	5	+	27869803	PATU8988S	viability after 35 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.1351993164340952	[528]	[227,239,NaN]	1	hSpCas9	negative selection	9837137
128446502	128446525	5	+	27869803	PATU8988S	viability after 31 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.08909132298208322	[782]	[255,428,NaN]	1	hSpCas9	negative selection	9919581
128519297	128519320	5	+	27869803	PATU8988S	viability after 31 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.5307325141984741	[737]	[253,642,NaN]	6	hSpCas9	negative selection	9919582
128527909	128527932	5	+	27869803	PATU8988S	viability after 31 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	-0.19405524771094074	[269]	[50,148,NaN]	-2	hSpCas9	negative selection	9919583
128530611	128530634	5	+	27869803	PATU8988S	viability after 31 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	0.43224649662405623	[141]	[82,67,NaN]	5	hSpCas9	negative selection	9919584
128536393	128536416	5	+	27869803	PATU8988S	viability after 31 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	-0.1517832686727414	[910]	[227,452,NaN]	-2	hSpCas9	negative selection	9919585
128537458	128537481	5	+	27869803	PATU8988S	viability after 31 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	0.7444607777058602	[528]	[304,414,NaN]	8	hSpCas9	negative selection	9919586
128446502	128446525	5	+	27869803	HPAFII	viability after 35 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.6180155369451779	[390]	[363,235,NaN]	4	hSpCas9	negative selection	10002030
128519297	128519320	5	+	27869803	HPAFII	viability after 35 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.20232531687667554	[415]	[262,218,NaN]	1	hSpCas9	negative selection	10002031
128527909	128527932	5	+	27869803	HPAFII	viability after 35 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	1.0548471036471343	[126]	[94,176,NaN]	7	hSpCas9	negative selection	10002032
128530611	128530634	5	+	27869803	HPAFII	viability after 35 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-0.5160821274354896	[47]	[0,34,NaN]	-3	hSpCas9	negative selection	10002033
128536393	128536416	5	+	27869803	HPAFII	viability after 35 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.2041258391137291	[350]	[72,352,NaN]	1	hSpCas9	negative selection	10002034
128537458	128537481	5	+	27869803	HPAFII	viability after 35 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	1.523710411719063	[185]	[107,453,NaN]	8	hSpCas9	negative selection	10002035
128446502	128446525	5	+	27869803	HPAFII	viability after 31 days	CACTCTGTTTGTGACCAGCAGGG	FBN2	ENSG00000138829	0.23445210820438311	[390]	[350,156,NaN]	1	hSpCas9	negative selection	10084479
128519297	128519320	5	+	27869803	HPAFII	viability after 31 days	ACCCATAAACACAAGCACAGCGG	FBN2	ENSG00000138829	0.0958687887434575	[415]	[338,151,NaN]	0	hSpCas9	negative selection	10084480
128527909	128527932	5	+	27869803	HPAFII	viability after 31 days	CTGGCAGTGGTCATCTGCACAGG	FBN2	ENSG00000138829	0.7903811582592764	[126]	[106,140,NaN]	6	hSpCas9	negative selection	10084481
128530611	128530634	5	+	27869803	HPAFII	viability after 31 days	GGTTGATGATATTTGCCCACTGG	FBN2	ENSG00000138829	-3.20844897601937	[47]	[0,4,NaN]	-9	hSpCas9	negative selection	10084482
128536393	128536416	5	+	27869803	HPAFII	viability after 31 days	AGCACTCACGGACAATGCACTGG	FBN2	ENSG00000138829	0.17866658902377613	[350]	[87,369,NaN]	1	hSpCas9	negative selection	10084483
128537458	128537481	5	+	27869803	HPAFII	viability after 31 days	GACCGAACCTGTTGCGGCGGCGG	FBN2	ENSG00000138829	1.2626323351469146	[185]	[148,360,NaN]	8	hSpCas9	negative selection	10084484
128395210	128395233	5	-	28162770	P31FUJ	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.46711640299650786	[212]	[345]	5	hSpCas9	negative selection	10155683
128345393	128345416	5	+	28162770	P31FUJ	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.4920905574512525	[287]	[475]	5	hSpCas9	negative selection	10155684
128345513	128345536	5	+	28162770	P31FUJ	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	0.21785920459518648	[119]	[163]	2	hSpCas9	negative selection	10155685
128537455	128537478	5	+	28162770	P31FUJ	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.013108023628206261	[225]	[267]	0	hSpCas9	negative selection	10155686
128527934	128527957	5	-	28162770	P31FUJ	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.5122119185253737	[428]	[718]	6	hSpCas9	negative selection	10155687
128446578	128446601	5	-	28162770	P31FUJ	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.43776216402931795	[288]	[459]	5	hSpCas9	negative selection	10155688
128393308	128393331	5	-	28162770	P31FUJ	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.2730660746281059	[217]	[211]	-3	hSpCas9	negative selection	10155689
128378796	128378819	5	-	28162770	P31FUJ	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	-0.6032932647399604	[286]	[221]	-5	hSpCas9	negative selection	10155690
128361743	128361766	5	+	28162770	P31FUJ	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	1.134568861234151	[49]	[128]	9	hSpCas9	negative selection	10155691
128357338	128357361	5	-	28162770	P31FUJ	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	-0.10303432944404922	[84]	[92]	-1	hSpCas9	negative selection	10155692
128395210	128395233	5	-	28162770	TF1	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10325049
128345393	128345416	5	+	28162770	TF1	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10325050
128345513	128345536	5	+	28162770	TF1	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10325051
128537455	128537478	5	+	28162770	TF1	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10325052
128527934	128527957	5	-	28162770	TF1	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	NaN	[NaN]	[543]	1	hSpCas9	negative selection	10325053
128446578	128446601	5	-	28162770	TF1	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	NaN	[NaN]	[344]	1	hSpCas9	negative selection	10325054
128393308	128393331	5	-	28162770	TF1	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10325055
128378796	128378819	5	-	28162770	TF1	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	NaN	[NaN]	[246]	1	hSpCas9	negative selection	10325056
128361743	128361766	5	+	28162770	TF1	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10325057
128357338	128357361	5	-	28162770	TF1	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10325058
128395210	128395233	5	-	28162770	SKM1	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.3479233034203068	[59]	[134]	3	hSpCas9	negative selection	10494415
128345393	128345416	5	+	28162770	SKM1	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.5124173410485537	[45]	[115]	5	hSpCas9	negative selection	10494416
128345513	128345536	5	+	28162770	SKM1	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	0.03463412680681721	[36]	[66]	0	hSpCas9	negative selection	10494417
128537455	128537478	5	+	28162770	SKM1	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.023275707179352373	[58]	[105]	0	hSpCas9	negative selection	10494418
128527934	128527957	5	-	28162770	SKM1	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.4158621320768823	[158]	[374]	4	hSpCas9	negative selection	10494419
128446578	128446601	5	-	28162770	SKM1	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.8809020600705676	[89]	[292]	8	hSpCas9	negative selection	10494420
128393308	128393331	5	-	28162770	SKM1	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.22942601319097422	[62]	[94]	-2	hSpCas9	negative selection	10494421
128378796	128378819	5	-	28162770	SKM1	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	-0.7224660244710911	[55]	[59]	-5	hSpCas9	negative selection	10494422
128361743	128361766	5	+	28162770	SKM1	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.12141477361162711	[12]	[24]	1	hSpCas9	negative selection	10494423
128357338	128357361	5	-	28162770	SKM1	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.8454229628911236	[16]	[53]	7	hSpCas9	negative selection	10494424
128395210	128395233	5	-	28162770	SKM1	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.3479233034203068	[59]	[134]	3	hSpCas9	negative selection	10663781
128345393	128345416	5	+	28162770	SKM1	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.5124173410485537	[45]	[115]	5	hSpCas9	negative selection	10663782
128345513	128345536	5	+	28162770	SKM1	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	0.03463412680681721	[36]	[66]	0	hSpCas9	negative selection	10663783
128537455	128537478	5	+	28162770	SKM1	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.023275707179352373	[58]	[105]	0	hSpCas9	negative selection	10663784
128527934	128527957	5	-	28162770	SKM1	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.4158621320768823	[158]	[374]	4	hSpCas9	negative selection	10663785
128446578	128446601	5	-	28162770	SKM1	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.8809020600705676	[89]	[292]	8	hSpCas9	negative selection	10663786
128393308	128393331	5	-	28162770	SKM1	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.22942601319097422	[62]	[94]	-2	hSpCas9	negative selection	10663787
128378796	128378819	5	-	28162770	SKM1	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	-0.7224660244710911	[55]	[59]	-5	hSpCas9	negative selection	10663788
128361743	128361766	5	+	28162770	SKM1	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.12141477361162711	[12]	[24]	1	hSpCas9	negative selection	10663789
128357338	128357361	5	-	28162770	SKM1	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.8454229628911236	[16]	[53]	7	hSpCas9	negative selection	10663790
128395210	128395233	5	-	28162770	PL21	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	-0.25929200414797715	[186]	[67]	-2	hSpCas9	negative selection	10833147
128345393	128345416	5	+	28162770	PL21	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	-0.7189403901271124	[207]	[54]	-5	hSpCas9	negative selection	10833148
128345513	128345536	5	+	28162770	PL21	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	0.04689335419363805	[128]	[57]	0	hSpCas9	negative selection	10833149
128537455	128537478	5	+	28162770	PL21	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.27133066234627295	[256]	[134]	2	hSpCas9	negative selection	10833150
128527934	128527957	5	-	28162770	PL21	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	-0.17970845632722354	[647]	[248]	-1	hSpCas9	negative selection	10833151
128446578	128446601	5	-	28162770	PL21	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	-0.5502882394834486	[322]	[95]	-4	hSpCas9	negative selection	10833152
128393308	128393331	5	-	28162770	PL21	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	1.0722221395685831	[164]	[150]	8	hSpCas9	negative selection	10833153
128378796	128378819	5	-	28162770	PL21	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	-0.26746593559367743	[176]	[63]	-2	hSpCas9	negative selection	10833154
128361743	128361766	5	+	28162770	PL21	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	-0.2917134818403544	[44]	[15]	-2	hSpCas9	negative selection	10833155
128357338	128357361	5	-	28162770	PL21	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.30066649044328464	[96]	[51]	2	hSpCas9	negative selection	10833156
128395210	128395233	5	-	28162770	P31FUJ	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.46711640299650786	[212]	[345]	5	hSpCas9	negative selection	11002513
128345393	128345416	5	+	28162770	P31FUJ	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.4920905574512525	[287]	[475]	5	hSpCas9	negative selection	11002514
128345513	128345536	5	+	28162770	P31FUJ	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	0.21785920459518648	[119]	[163]	2	hSpCas9	negative selection	11002515
128537455	128537478	5	+	28162770	P31FUJ	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.013108023628206261	[225]	[267]	0	hSpCas9	negative selection	11002516
128527934	128527957	5	-	28162770	P31FUJ	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.5122119185253737	[428]	[718]	6	hSpCas9	negative selection	11002517
128446578	128446601	5	-	28162770	P31FUJ	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.43776216402931795	[288]	[459]	5	hSpCas9	negative selection	11002518
128393308	128393331	5	-	28162770	P31FUJ	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.2730660746281059	[217]	[211]	-3	hSpCas9	negative selection	11002519
128378796	128378819	5	-	28162770	P31FUJ	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	-0.6032932647399604	[286]	[221]	-5	hSpCas9	negative selection	11002520
128361743	128361766	5	+	28162770	P31FUJ	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	1.134568861234151	[49]	[128]	9	hSpCas9	negative selection	11002521
128357338	128357361	5	-	28162770	P31FUJ	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	-0.10303432944404922	[84]	[92]	-1	hSpCas9	negative selection	11002522
128395210	128395233	5	-	28162770	OCIAML5	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.5325972793713281	[107]	[281]	4	hSpCas9	negative selection	11171879
128345393	128345416	5	+	28162770	OCIAML5	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.10729144463865699	[125]	[244]	0	hSpCas9	negative selection	11171880
128345513	128345536	5	+	28162770	OCIAML5	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	0.7328959298571591	[67]	[203]	6	hSpCas9	negative selection	11171881
128537455	128537478	5	+	28162770	OCIAML5	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.15692221236325776	[79]	[160]	1	hSpCas9	negative selection	11171882
128527934	128527957	5	-	28162770	OCIAML5	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.49045842863047895	[305]	[775]	4	hSpCas9	negative selection	11171883
128446578	128446601	5	-	28162770	OCIAML5	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.3632014160390694	[173]	[403]	3	hSpCas9	negative selection	11171884
128393308	128393331	5	-	28162770	OCIAML5	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	0.7388946704786021	[79]	[240]	6	hSpCas9	negative selection	11171885
128378796	128378819	5	-	28162770	OCIAML5	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.17809539964625565	[141]	[289]	1	hSpCas9	negative selection	11171886
128361743	128361766	5	+	28162770	OCIAML5	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.5671587253782805	[42]	[114]	5	hSpCas9	negative selection	11171887
128357338	128357361	5	-	28162770	OCIAML5	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	1.291524282764853	[42]	[189]	9	hSpCas9	negative selection	11171888
128395210	128395233	5	-	28162770	EOL1	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.9358335791170497	[381]	[384]	7	hSpCas9	negative selection	11341245
128345393	128345416	5	+	28162770	EOL1	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	-0.6711811600196919	[268]	[88]	-5	hSpCas9	negative selection	11341246
128345513	128345536	5	+	28162770	EOL1	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-0.3686486047735117	[173]	[70]	-3	hSpCas9	negative selection	11341247
128537455	128537478	5	+	28162770	EOL1	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.5255972564593274	[326]	[247]	5	hSpCas9	negative selection	11341248
128527934	128527957	5	-	28162770	EOL1	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.5928006156527263	[1031]	[819]	5	hSpCas9	negative selection	11341249
128446578	128446601	5	-	28162770	EOL1	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.6517228625439313	[620]	[513]	6	hSpCas9	negative selection	11341250
128393308	128393331	5	-	28162770	EOL1	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.6135481241126473	[211]	[72]	-4	hSpCas9	negative selection	11341251
128378796	128378819	5	-	28162770	EOL1	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.12673662218380138	[225]	[129]	1	hSpCas9	negative selection	11341252
128361743	128361766	5	+	28162770	EOL1	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	1.181705611067659	[40]	[48]	8	hSpCas9	negative selection	11341253
128357338	128357361	5	-	28162770	EOL1	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.2906756703684319	[89]	[57]	2	hSpCas9	negative selection	11341254
128395210	128395233	5	-	28162770	MOLM13	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.4726273005512419	[303]	[304]	3	hSpCas9	negative selection	11510611
128345393	128345416	5	+	28162770	MOLM13	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.6451939133524887	[259]	[293]	5	hSpCas9	negative selection	11510612
128345513	128345536	5	+	28162770	MOLM13	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-0.006791064161666804	[213]	[153]	0	hSpCas9	negative selection	11510613
128537455	128537478	5	+	28162770	MOLM13	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.3904848778589723	[267]	[253]	3	hSpCas9	negative selection	11510614
128527934	128527957	5	-	28162770	MOLM13	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.7306254324934527	[805]	[966]	5	hSpCas9	negative selection	11510615
128446578	128446601	5	-	28162770	MOLM13	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.6820141868974263	[499]	[579]	5	hSpCas9	negative selection	11510616
128393308	128393331	5	-	28162770	MOLM13	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	0.15330326199838454	[244]	[196]	1	hSpCas9	negative selection	11510617
128378796	128378819	5	-	28162770	MOLM13	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.214395742920391	[210]	[176]	1	hSpCas9	negative selection	11510618
128361743	128361766	5	+	28162770	MOLM13	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	-0.44284328035833376	[93]	[49]	-3	hSpCas9	negative selection	11510619
128357338	128357361	5	-	28162770	MOLM13	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	-0.5618579618494732	[97]	[47]	-3	hSpCas9	negative selection	11510620
128395210	128395233	5	-	28162770	HEL	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	1.026951205142062	[271]	[354]	8	hSpCas9	negative selection	11679977
128345393	128345416	5	+	28162770	HEL	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	-0.10933365455605765	[191]	[113]	-1	hSpCas9	negative selection	11679978
128345513	128345536	5	+	28162770	HEL	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-1.0292069703154392	[187]	[58]	-6	hSpCas9	negative selection	11679979
128537455	128537478	5	+	28162770	HEL	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	-0.20053566431218992	[304]	[169]	-1	hSpCas9	negative selection	11679980
128527934	128527957	5	-	28162770	HEL	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.5627236312785493	[796]	[753]	5	hSpCas9	negative selection	11679981
128446578	128446601	5	-	28162770	HEL	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.918948626581884	[435]	[527]	7	hSpCas9	negative selection	11679982
128393308	128393331	5	-	28162770	HEL	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.6895808687336009	[208]	[82]	-4	hSpCas9	negative selection	11679983
128378796	128378819	5	-	28162770	HEL	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.8440372217021808	[186]	[214]	7	hSpCas9	negative selection	11679984
128361743	128361766	5	+	28162770	HEL	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	-0.6202955738334368	[59]	[24]	-4	hSpCas9	negative selection	11679985
128357338	128357361	5	-	28162770	HEL	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.48801623720171516	[58]	[52]	4	hSpCas9	negative selection	11679986
128395210	128395233	5	-	28162770	MV411	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	1.2756344426134274	[151]	[309]	9	hSpCas9	negative selection	11849343
128345393	128345416	5	+	28162770	MV411	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	-0.4699752459620303	[170]	[103]	-3	hSpCas9	negative selection	11849344
128345513	128345536	5	+	28162770	MV411	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-0.46305583202224	[107]	[65]	-3	hSpCas9	negative selection	11849345
128537455	128537478	5	+	28162770	MV411	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.5028987369117682	[190]	[227]	4	hSpCas9	negative selection	11849346
128527934	128527957	5	-	28162770	MV411	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.7548069308336942	[521]	[741]	6	hSpCas9	negative selection	11849347
128446578	128446601	5	-	28162770	MV411	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.45097094486790745	[329]	[379]	4	hSpCas9	negative selection	11849348
128393308	128393331	5	-	28162770	MV411	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	-0.12941675460818053	[173]	[133]	-1	hSpCas9	negative selection	11849349
128378796	128378819	5	-	28162770	MV411	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.32544006278404847	[161]	[170]	3	hSpCas9	negative selection	11849350
128361743	128361766	5	+	28162770	MV411	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.8225522655475841	[48]	[72]	7	hSpCas9	negative selection	11849351
128357338	128357361	5	-	28162770	MV411	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	1.8059278401427405	[54]	[161]	9	hSpCas9	negative selection	11849352
128395210	128395233	5	-	28162770	MONOMAC1	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.8516369996761359	[101]	[210]	7	hSpCas9	negative selection	12018709
128345393	128345416	5	+	28162770	MONOMAC1	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	-0.15491137138687727	[134]	[138]	-1	hSpCas9	negative selection	12018710
128345513	128345536	5	+	28162770	MONOMAC1	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-0.2872346560311321	[98]	[92]	-3	hSpCas9	negative selection	12018711
128537455	128537478	5	+	28162770	MONOMAC1	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.22410085175570807	[117]	[157]	2	hSpCas9	negative selection	12018712
128527934	128527957	5	-	28162770	MONOMAC1	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.22415287920088556	[350]	[469]	2	hSpCas9	negative selection	12018713
128446578	128446601	5	-	28162770	MONOMAC1	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	-0.055860784098859306	[213]	[235]	0	hSpCas9	negative selection	12018714
128393308	128393331	5	-	28162770	MONOMAC1	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	0.1873038549963738	[94]	[123]	2	hSpCas9	negative selection	12018715
128378796	128378819	5	-	28162770	MONOMAC1	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	-0.4326650955526956	[145]	[123]	-4	hSpCas9	negative selection	12018716
128361743	128361766	5	+	28162770	MONOMAC1	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.6239930118951267	[29]	[52]	6	hSpCas9	negative selection	12018717
128357338	128357361	5	-	28162770	MONOMAC1	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.2659351292829921	[36]	[50]	2	hSpCas9	negative selection	12018718
128395210	128395233	5	-	28162770	OCIAML2	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.3412978266052669	[44]	[315]	3	hSpCas9	negative selection	12188075
128345393	128345416	5	+	28162770	OCIAML2	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	1.0753385438631313	[24]	[291]	8	hSpCas9	negative selection	12188076
128345513	128345536	5	+	28162770	OCIAML2	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-0.1487017303547986	[17]	[89]	-1	hSpCas9	negative selection	12188077
128537455	128537478	5	+	28162770	OCIAML2	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	0.6935588066510067	[27]	[250]	6	hSpCas9	negative selection	12188078
128527934	128527957	5	-	28162770	OCIAML2	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.5580656077583042	[111]	[913]	5	hSpCas9	negative selection	12188079
128446578	128446601	5	-	28162770	OCIAML2	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	0.3394704735542604	[74]	[525]	3	hSpCas9	negative selection	12188080
128393308	128393331	5	-	28162770	OCIAML2	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	0.6197564112149441	[28]	[246]	6	hSpCas9	negative selection	12188081
128378796	128378819	5	-	28162770	OCIAML2	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	0.05661717762270754	[33]	[195]	0	hSpCas9	negative selection	12188082
128361743	128361766	5	+	28162770	OCIAML2	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	-0.8856673245210047	[10]	[32]	-6	hSpCas9	negative selection	12188083
128357338	128357361	5	-	28162770	OCIAML2	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	1.3452871103188668	[11]	[168]	9	hSpCas9	negative selection	12188084
128395210	128395233	5	-	28162770	OCIAML3	viability	GCTGTGCACAAGAGCTCCCGGGG	FBN2	ENSG00000138829	0.6475783462455955	[47]	[226]	6	hSpCas9	negative selection	12357441
128345393	128345416	5	+	28162770	OCIAML3	viability	GGTTAGCAAAGCCAGCCCCGCGG	FBN2	ENSG00000138829	0.19258872156664356	[59]	[206]	1	hSpCas9	negative selection	12357442
128345513	128345536	5	+	28162770	OCIAML3	viability	GGAACTTTCCAGGAACGGGGTGG	FBN2	ENSG00000138829	-1.4829763279354193	[49]	[53]	-7	hSpCas9	negative selection	12357443
128537455	128537478	5	+	28162770	OCIAML3	viability	GCGGACCGAACCTGTTGCGGCGG	FBN2	ENSG00000138829	-0.871541615853072	[59]	[98]	-6	hSpCas9	negative selection	12357444
128527934	128527957	5	-	28162770	OCIAML3	viability	AGTGTGAGATGCATGAATGGTGG	FBN2	ENSG00000138829	0.18253246138288914	[168]	[578]	1	hSpCas9	negative selection	12357445
128446578	128446601	5	-	28162770	OCIAML3	viability	ATGAATGCCAGGCTATCCCAGGG	FBN2	ENSG00000138829	1.0100636833446979	[74]	[455]	8	hSpCas9	negative selection	12357446
128393308	128393331	5	-	28162770	OCIAML3	viability	GGAGGAATTCCAGGGAGTGCTGG	FBN2	ENSG00000138829	0.4712838199275561	[53]	[225]	4	hSpCas9	negative selection	12357447
128378796	128378819	5	-	28162770	OCIAML3	viability	AATGTCATGCTGGATTCCAGAGG	FBN2	ENSG00000138829	-0.228723176242419	[58]	[151]	-2	hSpCas9	negative selection	12357448
128361743	128361766	5	+	28162770	OCIAML3	viability	GTCCTGAACACATACCCTGGTGG	FBN2	ENSG00000138829	0.5103290194905721	[9]	[42]	5	hSpCas9	negative selection	12357449
128357338	128357361	5	-	28162770	OCIAML3	viability	GGGGCCTGCAGAAACAACCTTGG	FBN2	ENSG00000138829	0.7055526415347448	[12]	[63]	6	hSpCas9	negative selection	12357450