Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84467
• Symbol:FBN3
• Description:fibrillin 3

DataSource: http://genomecrispr.dkfz.de/#!/results/FBN3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
8141961	8141984	19	+	26472758	Jiyoye	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	-0.24609313260619153	[172]	[109]	-2	hSpCas9	negative selection	56420
8136434	8136457	19	+	26472758	Jiyoye	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.8091425254208904	[157]	[67]	-5	hSpCas9	negative selection	56421
8095979	8096002	19	+	26472758	Jiyoye	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	0.35867686381468356	[120]	[116]	2	hSpCas9	negative selection	56422
8085540	8085563	19	-	26472758	Jiyoye	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	0.7697454608905817	[62]	[80]	5	hSpCas9	negative selection	56423
8147450	8147473	19	-	26472758	Jiyoye	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.656954955913842	[91]	[43]	-5	hSpCas9	negative selection	56424
8147340	8147363	19	-	26472758	Jiyoye	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.37049471817940505	[238]	[232]	2	hSpCas9	negative selection	56425
8147313	8147336	19	-	26472758	Jiyoye	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	1.7138367197399251	[56]	[140]	8	hSpCas9	negative selection	56426
8146138	8146161	19	-	26472758	Jiyoye	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.5606442127449769	[132]	[67]	-4	hSpCas9	negative selection	56427
8142075	8142098	19	-	26472758	Jiyoye	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.7830422835040394	[83]	[108]	5	hSpCas9	negative selection	56428
8138255	8138278	19	+	26472758	Jiyoye	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	56430
8141961	8141984	19	+	26472758	KBM7	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.5393809490034073	[542,260]	[290,243]	6	hSpCas9	negative selection	247538
8136434	8136457	19	+	26472758	KBM7	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	0.3608734685976861	[341,199]	[111,202]	4	hSpCas9	negative selection	247539
8095979	8096002	19	+	26472758	KBM7	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	0.3904898495108047	[585,399]	[384,222]	4	hSpCas9	negative selection	247540
8085540	8085563	19	-	26472758	KBM7	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.7778973485530047	[398,211]	[70,90]	-6	hSpCas9	negative selection	247541
8147450	8147473	19	-	26472758	KBM7	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.8598419365527994	[247,61]	[39,35]	-6	hSpCas9	negative selection	247542
8147340	8147363	19	-	26472758	KBM7	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.018449168086980938	[1145,659]	[442,399]	0	hSpCas9	negative selection	247543
8147313	8147336	19	-	26472758	KBM7	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.4836104588578638	[710,845]	[502,532]	5	hSpCas9	negative selection	247544
8146138	8146161	19	-	26472758	KBM7	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.11392182581317967	[714,608]	[188,373]	-1	hSpCas9	negative selection	247545
8142075	8142098	19	-	26472758	KBM7	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.17376736799594372	[660,593]	[339,325]	1	hSpCas9	negative selection	247546
8138255	8138278	19	+	26472758	KBM7	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	1.0816969781589814	[0,0]	[0,0]	9	hSpCas9	negative selection	247548
8141961	8141984	19	+	26472758	Raji	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	1.0618688761212307	[160]	[77]	8	hSpCas9	negative selection	438656
8136434	8136457	19	+	26472758	Raji	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.9984111286489974	[197]	[22]	-6	hSpCas9	negative selection	438657
8095979	8096002	19	+	26472758	Raji	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	0.5295104594387627	[202]	[67]	5	hSpCas9	negative selection	438658
8085540	8085563	19	-	26472758	Raji	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.7524388065781402	[195]	[26]	-5	hSpCas9	negative selection	438659
8147450	8147473	19	-	26472758	Raji	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.3255758719025068	[53]	[9]	-3	hSpCas9	negative selection	438660
8147340	8147363	19	-	26472758	Raji	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.19188396210259095	[378]	[76]	-2	hSpCas9	negative selection	438661
8147313	8147336	19	-	26472758	Raji	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	-1.241344618857478	[488]	[47]	-7	hSpCas9	negative selection	438662
8146138	8146161	19	-	26472758	Raji	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-1.072127514897911	[452]	[49]	-7	hSpCas9	negative selection	438663
8142075	8142098	19	-	26472758	Raji	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.8510437821138139	[257]	[107]	7	hSpCas9	negative selection	438664
8138255	8138278	19	+	26472758	Raji	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	438666
8141961	8141984	19	+	26472758	K562	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.3436689733717594	[336]	[360]	2	hSpCas9	negative selection	629774
8136434	8136457	19	+	26472758	K562	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	0.1096219496277363	[212]	[193]	0	hSpCas9	negative selection	629775
8095979	8096002	19	+	26472758	K562	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.06020835326371206	[372]	[301]	0	hSpCas9	negative selection	629776
8085540	8085563	19	-	26472758	K562	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	0.17402939977504917	[209]	[199]	1	hSpCas9	negative selection	629777
8147450	8147473	19	-	26472758	K562	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.7806722532963837	[115]	[56]	-4	hSpCas9	negative selection	629778
8147340	8147363	19	-	26472758	K562	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.2492197139302681	[899]	[902]	2	hSpCas9	negative selection	629779
8147313	8147336	19	-	26472758	K562	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	-0.22461366125312623	[489]	[353]	-1	hSpCas9	negative selection	629780
8146138	8146161	19	-	26472758	K562	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-1.4721406558379222	[584]	[177]	-6	hSpCas9	negative selection	629781
8142075	8142098	19	-	26472758	K562	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.5998711320706667	[586]	[750]	5	hSpCas9	negative selection	629782
8138255	8138278	19	+	26472758	K562	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	629784
8141726	8141749	19	+	26627737	DLD1	viability	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	1.2390551192635355	[604]	[453,450,435]	9	hSpCas9	negative selection	807706
8142057	8142080	19	-	26627737	DLD1	viability	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.3381137447718068	[357]	[162,232,46]	3	hSpCas9	negative selection	807707
8144893	8144916	19	+	26627737	DLD1	viability	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.2363818620042848	[1143]	[456,510,315]	2	hSpCas9	negative selection	807708
8145870	8145893	19	-	26627737	DLD1	viability	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.3442573220916728	[282]	[71,114,144]	3	hSpCas9	negative selection	807709
8146149	8146172	19	+	26627737	DLD1	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.43642869832375003	[685]	[258,118,103]	-4	hSpCas9	negative selection	807710
8147095	8147118	19	+	26627737	DLD1	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.6247476231057248	[777]	[134,249,100]	-6	hSpCas9	negative selection	807711
8141726	8141749	19	+	26627737	GBM cells	viability after 5 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	-0.0869765256988787	[406]	[199,210]	-1	hSpCas9	negative selection	890021
8142057	8142080	19	-	26627737	GBM cells	viability after 5 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.2684873420081564	[136]	[80,95]	4	hSpCas9	negative selection	890022
8144893	8144916	19	+	26627737	GBM cells	viability after 5 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.193047484632064	[565]	[334,358]	3	hSpCas9	negative selection	890023
8145870	8145893	19	-	26627737	GBM cells	viability after 5 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.40550531205396945	[144]	[110,94]	6	hSpCas9	negative selection	890024
8146149	8146172	19	+	26627737	GBM cells	viability after 5 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.007956634180975475	[483]	[314,206]	0	hSpCas9	negative selection	890025
8147095	8147118	19	+	26627737	GBM cells	viability after 5 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.2520939132139969	[321]	[179,109]	-4	hSpCas9	negative selection	890026
8141726	8141749	19	+	26627737	GBM cells	viability after 13 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	-0.01640946057393533	[406]	[262,181]	0	hSpCas9	negative selection	972336
8142057	8142080	19	-	26627737	GBM cells	viability after 13 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.4730412318123144	[136]	[111,95]	6	hSpCas9	negative selection	972337
8144893	8144916	19	+	26627737	GBM cells	viability after 13 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.04855874317786468	[565]	[369,274]	0	hSpCas9	negative selection	972338
8145870	8145893	19	-	26627737	GBM cells	viability after 13 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.03034093634868662	[144]	[81,78]	0	hSpCas9	negative selection	972339
8146149	8146172	19	+	26627737	GBM cells	viability after 13 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.060996422643610604	[483]	[275,231]	0	hSpCas9	negative selection	972340
8147095	8147118	19	+	26627737	GBM cells	viability after 13 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	0.38039597256149443	[321]	[238,217]	5	hSpCas9	negative selection	972341
8141726	8141749	19	+	26627737	GBM cells	viability after 21 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	-0.16302400814727946	[406]	[185,207]	-1	hSpCas9	negative selection	1054651
8142057	8142080	19	-	26627737	GBM cells	viability after 21 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.05439033763204426	[136]	[93,61]	0	hSpCas9	negative selection	1054652
8144893	8144916	19	+	26627737	GBM cells	viability after 21 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.17182390005849602	[565]	[348,343]	1	hSpCas9	negative selection	1054653
8145870	8145893	19	-	26627737	GBM cells	viability after 21 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.016630886139423984	[144]	[86,72]	0	hSpCas9	negative selection	1054654
8146149	8146172	19	+	26627737	GBM cells	viability after 21 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.8649250441421958	[483]	[158,130]	-6	hSpCas9	negative selection	1054655
8147095	8147118	19	+	26627737	GBM cells	viability after 21 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	1.0533187871954568	[321]	[361,363]	9	hSpCas9	negative selection	1054656
8141726	8141749	19	+	26627737	RPE1	viability after 9 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.5216284286943155	[1352]	[556,673]	3	hSpCas9	negative selection	1136966
8142057	8142080	19	-	26627737	RPE1	viability after 9 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.5859360271691181	[1044]	[227,204]	-4	hSpCas9	negative selection	1136967
8144893	8144916	19	+	26627737	RPE1	viability after 9 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.019035191168092824	[1836]	[456,744]	0	hSpCas9	negative selection	1136968
8145870	8145893	19	-	26627737	RPE1	viability after 9 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	6.400680758463912	[8]	[172,321]	9	hSpCas9	negative selection	1136969
8146149	8146172	19	+	26627737	RPE1	viability after 9 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.217765542933333	[637]	[464,463]	7	hSpCas9	negative selection	1136970
8147095	8147118	19	+	26627737	RPE1	viability after 9 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.7124831549816436	[1822]	[401,278]	-5	hSpCas9	negative selection	1136971
8141726	8141749	19	+	26627737	RPE1	viability after 12 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.5355897720997108	[1352]	[574,475]	3	hSpCas9	negative selection	1219281
8142057	8142080	19	-	26627737	RPE1	viability after 12 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.3649914905181809	[1044]	[217,217]	-2	hSpCas9	negative selection	1219282
8144893	8144916	19	+	26627737	RPE1	viability after 12 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.3156073125487142	[1836]	[587,641]	2	hSpCas9	negative selection	1219283
8145870	8145893	19	-	26627737	RPE1	viability after 12 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	6.7722970021783	[8]	[240,288]	9	hSpCas9	negative selection	1219284
8146149	8146172	19	+	26627737	RPE1	viability after 12 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.4823224585915529	[637]	[424,535]	7	hSpCas9	negative selection	1219285
8147095	8147118	19	+	26627737	RPE1	viability after 12 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.5781841110396926	[1822]	[414,235]	-4	hSpCas9	negative selection	1219286
8141726	8141749	19	+	26627737	RPE1	viability after 15 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.44743984653161395	[1352]	[667,380]	3	hSpCas9	negative selection	1301596
8142057	8142080	19	-	26627737	RPE1	viability after 15 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.24758885597197275	[1044]	[136,356]	-1	hSpCas9	negative selection	1301597
8144893	8144916	19	+	26627737	RPE1	viability after 15 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.7361010212668768	[1836]	[1030,705]	4	hSpCas9	negative selection	1301598
8145870	8145893	19	-	26627737	RPE1	viability after 15 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	6.923244647081819	[8]	[196,416]	9	hSpCas9	negative selection	1301599
8146149	8146172	19	+	26627737	RPE1	viability after 15 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.6155427571585732	[637]	[438,662]	8	hSpCas9	negative selection	1301600
8147095	8147118	19	+	26627737	RPE1	viability after 15 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.4024171966713088	[1822]	[380,398]	-3	hSpCas9	negative selection	1301601
8141726	8141749	19	+	26627737	RPE1	viability after 18 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.26243114090550346	[1352]	[480,391]	1	hSpCas9	negative selection	1383911
8142057	8142080	19	-	26627737	RPE1	viability after 18 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.17061690004241598	[1044]	[212,428]	1	hSpCas9	negative selection	1383912
8144893	8144916	19	+	26627737	RPE1	viability after 18 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.2613578562610963	[1836]	[643,540]	1	hSpCas9	negative selection	1383913
8145870	8145893	19	-	26627737	RPE1	viability after 18 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	6.696263269029958	[8]	[145,364]	9	hSpCas9	negative selection	1383914
8146149	8146172	19	+	26627737	RPE1	viability after 18 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.8645118478239686	[637]	[494,767]	8	hSpCas9	negative selection	1383915
8147095	8147118	19	+	26627737	RPE1	viability after 18 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-1.0938521413183568	[1822]	[273,183]	-6	hSpCas9	negative selection	1383916
8141726	8141749	19	+	26627737	HeLa	viability after 8 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.1996160043391786	[882]	[464,304,550]	2	hSpCas9	negative selection	1466226
8142057	8142080	19	-	26627737	HeLa	viability after 8 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.2850592236935226	[467]	[158,208,133]	-3	hSpCas9	negative selection	1466227
8144893	8144916	19	+	26627737	HeLa	viability after 8 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.7821639187361711	[820]	[745,599,531]	6	hSpCas9	negative selection	1466228
8145870	8145893	19	-	26627737	HeLa	viability after 8 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	-0.6249838108071756	[477]	[156,154,99]	-6	hSpCas9	negative selection	1466229
8146149	8146172	19	+	26627737	HeLa	viability after 8 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.34445994623956033	[885]	[567,243,166]	-3	hSpCas9	negative selection	1466230
8147095	8147118	19	+	26627737	HeLa	viability after 8 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.04161070468903638	[499]	[212,261,162]	0	hSpCas9	negative selection	1466231
8141726	8141749	19	+	26627737	HeLa	viability after 12 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.4286787051583629	[882]	[606,508,358]	3	hSpCas9	negative selection	1548541
8142057	8142080	19	-	26627737	HeLa	viability after 12 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-1.5522886064512964	[467]	[47,134,6]	-8	hSpCas9	negative selection	1548542
8144893	8144916	19	+	26627737	HeLa	viability after 12 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.17369480187588215	[820]	[194,435,505]	1	hSpCas9	negative selection	1548543
8145870	8145893	19	-	26627737	HeLa	viability after 12 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	-0.5292697686458236	[477]	[95,74,244]	-5	hSpCas9	negative selection	1548544
8146149	8146172	19	+	26627737	HeLa	viability after 12 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.016458336245058547	[885]	[647,314,161]	0	hSpCas9	negative selection	1548545
8147095	8147118	19	+	26627737	HeLa	viability after 12 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.29986839612592997	[499]	[98,191,207]	-3	hSpCas9	negative selection	1548546
8141726	8141749	19	+	26627737	HeLa	viability after 15 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	-0.14573380173987305	[882]	[288,279,412]	-1	hSpCas9	negative selection	1630856
8142057	8142080	19	-	26627737	HeLa	viability after 15 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.7799600904380668	[467]	[33,138,164]	-6	hSpCas9	negative selection	1630857
8144893	8144916	19	+	26627737	HeLa	viability after 15 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.447383267475818	[820]	[427,478,460]	4	hSpCas9	negative selection	1630858
8145870	8145893	19	-	26627737	HeLa	viability after 15 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	-0.12612139270123102	[477]	[52,202,288]	-1	hSpCas9	negative selection	1630859
8146149	8146172	19	+	26627737	HeLa	viability after 15 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.3015978652895762	[885]	[474,247,140]	-3	hSpCas9	negative selection	1630860
8147095	8147118	19	+	26627737	HeLa	viability after 15 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.20192901946478634	[499]	[324,50,150]	-2	hSpCas9	negative selection	1630861
8141726	8141749	19	+	26627737	HeLa	viability after 18 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	-0.12171079837790177	[882]	[209,224,412]	-1	hSpCas9	negative selection	1713171
8142057	8142080	19	-	26627737	HeLa	viability after 18 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.752741204381447	[467]	[22,119,164]	-6	hSpCas9	negative selection	1713172
8144893	8144916	19	+	26627737	HeLa	viability after 18 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.4377927708015399	[820]	[276,401,460]	3	hSpCas9	negative selection	1713173
8145870	8145893	19	-	26627737	HeLa	viability after 18 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	-0.08040143012236428	[477]	[41,173,288]	0	hSpCas9	negative selection	1713174
8146149	8146172	19	+	26627737	HeLa	viability after 18 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.2980286305513098	[885]	[329,192,140]	-3	hSpCas9	negative selection	1713175
8147095	8147118	19	+	26627737	HeLa	viability after 18 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.18794807300004734	[499]	[219,43,150]	-2	hSpCas9	negative selection	1713176
8141726	8141749	19	+	26627737	HCT116	viability after 6 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	1.7524552689246298	[711]	[516,299]	8	hSpCas9	negative selection	1795486
8142057	8142080	19	-	26627737	HCT116	viability after 6 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.17458336685298295	[714]	[287,37]	1	hSpCas9	negative selection	1795487
8144893	8144916	19	+	26627737	HCT116	viability after 6 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	-0.5354949769649214	[1602]	[198,159]	-3	hSpCas9	negative selection	1795488
8145870	8145893	19	-	26627737	HCT116	viability after 6 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.33155249805826753	[358]	[90,59]	1	hSpCas9	negative selection	1795489
8146149	8146172	19	+	26627737	HCT116	viability after 6 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.0945599245545146	[801]	[285,259]	6	hSpCas9	negative selection	1795490
8147095	8147118	19	+	26627737	HCT116	viability after 6 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	1.598522039294012	[342]	[132,179]	7	hSpCas9	negative selection	1795491
8141726	8141749	19	+	26627737	HCT116	viability after 8 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.9287993009600599	[408]	[246,619,416]	8	hSpCas9	negative selection	1877801
8142057	8142080	19	-	26627737	HCT116	viability after 8 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.07561790013433414	[244]	[84,216,123]	0	hSpCas9	negative selection	1877802
8144893	8144916	19	+	26627737	HCT116	viability after 8 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	-0.4126358378525039	[824]	[291,417,313]	-5	hSpCas9	negative selection	1877803
8145870	8145893	19	-	26627737	HCT116	viability after 8 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.7086886509769547	[108]	[99,53,139]	6	hSpCas9	negative selection	1877804
8146149	8146172	19	+	26627737	HCT116	viability after 8 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.33401175643738124	[309]	[186,205,251]	3	hSpCas9	negative selection	1877805
8147095	8147118	19	+	26627737	HCT116	viability after 8 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.03308787633102642	[271]	[119,174,143]	0	hSpCas9	negative selection	1877806
8141726	8141749	19	+	26627737	HCT116	viability after 9 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.6135062903700815	[711]	[396,206]	4	hSpCas9	negative selection	1960116
8142057	8142080	19	-	26627737	HCT116	viability after 9 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-1.149940468851916	[714]	[99,74]	-7	hSpCas9	negative selection	1960117
8144893	8144916	19	+	26627737	HCT116	viability after 9 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.05044457491069032	[1602]	[497,399]	0	hSpCas9	negative selection	1960118
8145870	8145893	19	-	26627737	HCT116	viability after 9 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	-1.2007812415277979	[358]	[34,46]	-7	hSpCas9	negative selection	1960119
8146149	8146172	19	+	26627737	HCT116	viability after 9 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.4039028629222068	[801]	[167,156]	-3	hSpCas9	negative selection	1960120
8147095	8147118	19	+	26627737	HCT116	viability after 9 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	1.801966488654676	[342]	[334,306]	9	hSpCas9	negative selection	1960121
8141726	8141749	19	+	26627737	HCT116	viability after 12 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.7435097448815724	[408]	[291,460,334]	6	hSpCas9	negative selection	2042431
8142057	8142080	19	-	26627737	HCT116	viability after 12 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.6214476750416779	[244]	[104,304,194]	6	hSpCas9	negative selection	2042432
8144893	8144916	19	+	26627737	HCT116	viability after 12 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	-0.3995006359821063	[824]	[418,322,235]	-4	hSpCas9	negative selection	2042433
8145870	8145893	19	-	26627737	HCT116	viability after 12 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	1.352152766533724	[108]	[192,79,159]	9	hSpCas9	negative selection	2042434
8146149	8146172	19	+	26627737	HCT116	viability after 12 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.545018655329524	[309]	[285,243,178]	5	hSpCas9	negative selection	2042435
8147095	8147118	19	+	26627737	HCT116	viability after 12 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.08054076958290701	[271]	[150,169,83]	-1	hSpCas9	negative selection	2042436
8141726	8141749	19	+	26627737	HCT116	viability after 15 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	1.097898253456637	[408]	[336,556,592]	8	hSpCas9	negative selection	2124746
8142057	8142080	19	-	26627737	HCT116	viability after 15 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.5449245975447385	[244]	[42,340,211]	5	hSpCas9	negative selection	2124747
8144893	8144916	19	+	26627737	HCT116	viability after 15 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	-0.1376378175850339	[824]	[684,290,347]	-1	hSpCas9	negative selection	2124748
8145870	8145893	19	-	26627737	HCT116	viability after 15 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	1.0245919873128568	[108]	[203,111,75]	8	hSpCas9	negative selection	2124749
8146149	8146172	19	+	26627737	HCT116	viability after 15 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.5532112302948777	[309]	[140,360,266]	5	hSpCas9	negative selection	2124750
8147095	8147118	19	+	26627737	HCT116	viability after 15 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.036262540884626854	[271]	[217,178,68]	0	hSpCas9	negative selection	2124751
8141726	8141749	19	+	26627737	HCT116	viability after 18 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.4930391846689173	[408]	[213,431,173]	4	hSpCas9	negative selection	2207061
8142057	8142080	19	-	26627737	HCT116	viability after 18 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.04419275932494593	[244]	[75,118,150]	0	hSpCas9	negative selection	2207062
8144893	8144916	19	+	26627737	HCT116	viability after 18 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	-0.3687172119427047	[824]	[282,333,307]	-3	hSpCas9	negative selection	2207063
8145870	8145893	19	-	26627737	HCT116	viability after 18 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	1.1724306413751449	[108]	[170,22,170]	8	hSpCas9	negative selection	2207064
8146149	8146172	19	+	26627737	HCT116	viability after 18 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.34821658270953987	[309]	[174,302,81]	3	hSpCas9	negative selection	2207065
8147095	8147118	19	+	26627737	HCT116	viability after 18 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.023534852139730056	[271]	[158,160,62]	0	hSpCas9	negative selection	2207066
8147641	8147664	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAAGCGGTGAACAGTCAGAGG	FBN3	ENSG00000142449	0.8872609685110588	[3,1]	[0,0]	3	dCas9-VP64	positive selection	2459705
8147591	8147614	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGCAGCCCCGGGGCCTCTGGG	FBN3	ENSG00000142449	-0.6385327131773788	[60,15]	[1,7]	-3	dCas9-VP64	positive selection	2459706
8147616	8147639	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGGGGCTGGATGCCTCCTTGGG	FBN3	ENSG00000142449	-2.199936727814153	[318,85]	[9,7]	-9	dCas9-VP64	positive selection	2459707
8084997	8085020	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCTGAAGAAG	FBN3	ENSG00000142449	6.35516198632701	[126,1064]	[8429,13566]	9	dCas9-VP64	positive selection	2467016
8134451	8134474	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCAAG	FBN3	ENSG00000142449	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468634
8107566	8107589	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGATGGATGGATGGATGGAGGG	FBN3	ENSG00000142449	2.7644531499590617	[51,2]	[77,0]	8	dCas9-VP64	positive selection	2471310
8147641	8147664	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAAGCGGTGAACAGTCAGAGG	FBN3	ENSG00000142449	-1.4939876454024357	[117,122]	[16,9]	-9	dCas9-VP64	positive selection	2554960
8147591	8147614	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGCAGCCCCGGGGCCTCTGGG	FBN3	ENSG00000142449	-1.1708251301624595	[122,12]	[13,4]	-9	dCas9-VP64	positive selection	2554961
8147616	8147639	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGGGGCTGGATGCCTCCTTGGG	FBN3	ENSG00000142449	-0.1951468339825304	[58,186]	[18,48]	-2	dCas9-VP64	positive selection	2554962
8084997	8085020	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCTGAAGAAG	FBN3	ENSG00000142449	6.970706058095935	[220,255]	[14367,5508]	9	dCas9-VP64	positive selection	2562271
8134451	8134474	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCAAG	FBN3	ENSG00000142449	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563889
8107566	8107589	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGATGGATGGATGGATGGAGGG	FBN3	ENSG00000142449	-0.745179068402318	[185,151]	[42,22]	-7	dCas9-VP64	positive selection	2566565
8136419	8136442	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCCCACGTTACACTCGCAGCGG	FBN3	ENSG00000142449	-0.3040984311672815	[3,3]	[3,1]	-4	hSpCas9	positive selection	2988069
8112032	8112055	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCCTGTCTCAACATCCCGGGG	FBN3	ENSG00000142449	0.027433507464506984	[2,3]	[2,2]	0	hSpCas9	positive selection	2988070
8136419	8136442	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCCCACGTTACACTCGCAGCGG	FBN3	ENSG00000142449	-0.29835613718085335	[3,3]	[3,0]	-4	hSpCas9	positive selection	3055927
8112032	8112055	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCCTGTCTCAACATCCCGGGG	FBN3	ENSG00000142449	0.2977071677118387	[2,2]	[2,2]	5	hSpCas9	positive selection	3055928
8147308	8147331		+	24336571	A375	resistance to PLX after 7 days	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.2971658710782288	[9,14]	[14,15]	7	hSpCas9	positive selection	3114138
8147095	8147118		+	24336571	A375	resistance to PLX after 7 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.13684839789763623	[15,16]	[13,14]	-4	hSpCas9	positive selection	3114139
8147172	8147195		-	24336571	A375	resistance to PLX after 7 days	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.08916225497891611	[9,10]	[8,9]	-3	hSpCas9	positive selection	3114140
8147441	8147464		-	24336571	A375	resistance to PLX after 7 days	GTATTTGGCAAGGGGCCCCCTGG	FBN3	ENSG00000142449	-0.07731006889152736	[3,2]	[2,2]	-2	hSpCas9	positive selection	3114141
8147308	8147331		+	24336571	A375	resistance to PLX after 14 days	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.07254939163616211	[10,13]	[5,5]	0	hSpCas9	positive selection	3171931
8147095	8147118		+	24336571	A375	resistance to PLX after 14 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	1.0584029899816418	[6,14]	[11,9]	8	hSpCas9	positive selection	3171932
8147172	8147195		-	24336571	A375	resistance to PLX after 14 days	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.2570285135391029	[8,8]	[2,2]	-3	hSpCas9	positive selection	3171933
8147441	8147464		-	24336571	A375	resistance to PLX after 14 days	GTATTTGGCAAGGGGCCCCCTGG	FBN3	ENSG00000142449	0.18012123694777582	[4,2]	[1,1]	2	hSpCas9	positive selection	3171934
8147308	8147331		+	24336571	A375	viability after 7 days	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.29485570212122475	[10]	[9,14]	4	hSpCas9	negative selection	3229724
8147095	8147118		+	24336571	A375	viability after 7 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.8532256783581907	[31]	[15,16]	-8	hSpCas9	negative selection	3229725
8147172	8147195		-	24336571	A375	viability after 7 days	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.34646079971729227	[7]	[9,10]	5	hSpCas9	negative selection	3229726
8147441	8147464		-	24336571	A375	viability after 7 days	GTATTTGGCAAGGGGCCCCCTGG	FBN3	ENSG00000142449	-0.39649990103064314	[4]	[3,2]	-5	hSpCas9	negative selection	3229727
8147308	8147331		+	24336571	A375	viability after 14 days	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.28124598730189926	[10]	[10,13]	3	hSpCas9	negative selection	3287517
8147095	8147118		+	24336571	A375	viability after 14 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-1.385795896114551	[31]	[6,14]	-9	hSpCas9	negative selection	3287518
8147172	8147195		-	24336571	A375	viability after 14 days	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.17727762975654465	[7]	[8,8]	2	hSpCas9	negative selection	3287519
8147441	8147464		-	24336571	A375	viability after 14 days	GTATTTGGCAAGGGGCCCCCTGG	FBN3	ENSG00000142449	-0.2086393852029822	[4]	[4,2]	-2	hSpCas9	negative selection	3287520
8146204	8146227	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.8412945499311035	[68,101]	[0,0]	4	hSpCas9	positive selection	3349614
8147095	8147118	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.0269875916417496	[137,173]	[0,0]	0	hSpCas9	positive selection	3349615
8147468	8147491	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	1.412902484314484	[50,63]	[0,0]	6	hSpCas9	positive selection	3349616
8147172	8147195	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.8479352753081334	[84,84]	[0,0]	4	hSpCas9	positive selection	3368819
8147308	8147331	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	-1.7678133508326732	[520,520]	[0,0]	-9	hSpCas9	positive selection	3368820
8146149	8146172	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.449971289388231	[55,55]	[0,0]	6	hSpCas9	positive selection	3368821
8136418	8136441	19	+	26780180	HT29	viability (Avana library 4 designs)	AGCCCACGTTACACTCGCAGCGG	FBN3	ENSG00000142449	1.0321779748484	[]	[]	4	hSpCas9	negative selection	3424962
8112032	8112055	19	-	26780180	HT29	viability (Avana library 4 designs)	CCTCCTGTCTCAACATCCCGGGG	FBN3	ENSG00000142449	2.85540333368462	[]	[]	8	hSpCas9	negative selection	3424963
8136256	8136279	19	+	26780180	HT29	viability (Avana library 4 designs)	GGATGTTGACGCAGTCACCGTGG	FBN3	ENSG00000142449	2.19314194425062	[]	[]	7	hSpCas9	negative selection	3424964
8138402	8138425	19	+	26780180	HT29	viability (Avana library 4 designs)	TCTTACTCACTGGAGCCCCGAGG	FBN3	ENSG00000142449	0.685456171534005	[]	[]	2	hSpCas9	negative selection	3424965
8138402	8138425	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTACTCACTGGAGCCCCGAGG	FBN3	ENSG00000142449	0.966631463673101	[]	[]	1	hSpCas9	negative selection	3506865
8136256	8136279	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGTTGACGCAGTCACCGTGG	FBN3	ENSG00000142449	2.8748527045164	[]	[]	4	hSpCas9	negative selection	3506866
8112032	8112055	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCCTGTCTCAACATCCCGGGG	FBN3	ENSG00000142449	-1.23322493436055	[]	[]	-1	hSpCas9	negative selection	3506867
8136418	8136441	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCCCACGTTACACTCGCAGCGG	FBN3	ENSG00000142449	-3.77839848256335	[]	[]	-4	hSpCas9	negative selection	3506868
8138402	8138425	19	+	26780180	A375	viability (Avana lentiGuide)	TCTTACTCACTGGAGCCCCGAGG	FBN3	ENSG00000142449	2.17844325049492	[]	[]	2	hSpCas9	negative selection	3615524
8136256	8136279	19	+	26780180	A375	viability (Avana lentiGuide)	GGATGTTGACGCAGTCACCGTGG	FBN3	ENSG00000142449	1.39957111126445	[]	[]	1	hSpCas9	negative selection	3615525
8112032	8112055	19	-	26780180	A375	viability (Avana lentiGuide)	CCTCCTGTCTCAACATCCCGGGG	FBN3	ENSG00000142449	6.10149729807361	[]	[]	5	hSpCas9	negative selection	3615526
8136418	8136441	19	+	26780180	A375	viability (Avana lentiGuide)	AGCCCACGTTACACTCGCAGCGG	FBN3	ENSG00000142449	5.6829210087532	[]	[]	5	hSpCas9	negative selection	3615527
8138402	8138425	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTACTCACTGGAGCCCCGAGG	FBN3	ENSG00000142449	-0.02524624146346531	[4]	[4,4]	0	hSpCas9	positive selection	3724183
8136256	8136279	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGTTGACGCAGTCACCGTGG	FBN3	ENSG00000142449	0.1121962168656617	[4]	[4,4]	3	hSpCas9	positive selection	3724184
8112032	8112055	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCCTGTCTCAACATCCCGGGG	FBN3	ENSG00000142449	-0.559977273820557	[4]	[3,2]	-7	hSpCas9	positive selection	3724185
8136418	8136441	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCCCACGTTACACTCGCAGCGG	FBN3	ENSG00000142449	-0.3907570061999588	[5]	[4,3]	-5	hSpCas9	positive selection	3724186
8138402	8138425	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTACTCACTGGAGCCCCGAGG	FBN3	ENSG00000142449	0.020759316118907717	[5]	[3,5]	0	hSpCas9	positive selection	3832790
8136256	8136279	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGTTGACGCAGTCACCGTGG	FBN3	ENSG00000142449	-0.32416736816769753	[5]	[3,2]	-4	hSpCas9	positive selection	3832791
8112032	8112055	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCCTGTCTCAACATCCCGGGG	FBN3	ENSG00000142449	-0.4035261208724211	[5]	[3,2]	-5	hSpCas9	positive selection	3832792
8136418	8136441	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCCCACGTTACACTCGCAGCGG	FBN3	ENSG00000142449	0.13998200722410808	[6]	[4,6]	3	hSpCas9	positive selection	3832793
8147308	8147331	19	+	26780180	A375	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.321506516751667	[]	[]	0	hSpCas9	negative selection	3940046
8147095	8147118	19	+	26780180	A375	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	1.31238791028528	[]	[]	7	hSpCas9	negative selection	3940047
8146149	8146172	19	+	26780180	A375	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.46816436265838	[]	[]	8	hSpCas9	negative selection	3940048
8147172	8147195	19	-	26780180	A375	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	1.03008041754229	[]	[]	5	hSpCas9	negative selection	3940049
8146204	8146227	19	-	26780180	A375	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.570908499437652	[]	[]	1	hSpCas9	negative selection	3940050
8147468	8147491	19	-	26780180	A375	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	0.838969945410819	[]	[]	3	hSpCas9	negative selection	3940051
8147308	8147331	19	+	26780180	HT29	viability (GeCKOv2 library)	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.744494013962533	[]	[]	3	hSpCas9	negative selection	4048012
8147095	8147118	19	+	26780180	HT29	viability (GeCKOv2 library)	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	1.15001046860368	[]	[]	5	hSpCas9	negative selection	4048013
8146149	8146172	19	+	26780180	HT29	viability (GeCKOv2 library)	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	2.12980121446155	[]	[]	9	hSpCas9	negative selection	4048014
8147172	8147195	19	-	26780180	HT29	viability (GeCKOv2 library)	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	1.22382463436756	[]	[]	6	hSpCas9	negative selection	4048015
8146204	8146227	19	-	26780180	HT29	viability (GeCKOv2 library)	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.422453305081185	[]	[]	1	hSpCas9	negative selection	4048016
8147468	8147491	19	-	26780180	HT29	viability (GeCKOv2 library)	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	0.999348520263462	[]	[]	4	hSpCas9	negative selection	4048017
8147308	8147331	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	-0.2560950777126574	[3]	[1,2]	-6	hSpCas9	positive selection	4137132
8147095	8147118	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	0.1443836616948888	[4]	[2,3]	3	hSpCas9	positive selection	4137133
8147172	8147195	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.1358468561052055	[4]	[3,1]	-3	hSpCas9	positive selection	4137134
8147441	8147464	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTATTTGGCAAGGGGCCCCCTGG	FBN3	ENSG00000142449	-0.36492692176882957	[1]	[0,0]	-7	hSpCas9	positive selection	4137135
8147308	8147331	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	-0.12505822165652408	[2]	[0,2,0,0]	-2	hSpCas9	positive selection	4201154
8147095	8147118	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	0.9256852852546837	[4]	[3,3,2,4]	6	hSpCas9	positive selection	4201155
8147172	8147195	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.26554223193440096	[3]	[2,0,1,1]	2	hSpCas9	positive selection	4201156
8147441	8147464	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTATTTGGCAAGGGGCCCCCTGG	FBN3	ENSG00000142449	-0.11078446855427959	[1]	[0,0,0,0]	-1	hSpCas9	positive selection	4201157
8146204	8146227	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.05916628459819015	[2]	[2,1]	1	hSpCas9	positive selection	4270650
8147095	8147118	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.12921341704341957	[3]	[2,1]	-3	hSpCas9	positive selection	4270651
8147468	8147491	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.3305110940277551	[2]	[1,0]	-6	hSpCas9	positive selection	4270652
8147172	8147195	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.3060083381594648	[2]	[1,2]	6	hSpCas9	positive selection	4334914
8147308	8147331	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.20299979770807286	[4]	[4,3]	4	hSpCas9	positive selection	4334915
8146149	8146172	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.9230596639126889	[1]	[0,0]	-9	hSpCas9	positive selection	4334916
8117178	8117200	19	-	27760321	OCIAML3	viability	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	-0.2456883364556086	[297,215]	[133,211]	-3	hSpCas9	negative selection	4400481
8126468	8126490	19	+	27760321	OCIAML3	viability	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.33725764875442976	[838,772]	[715,900]	4	hSpCas9	negative selection	4400482
8133050	8133072	19	-	27760321	OCIAML3	viability	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.14055253060195028	[484,363]	[236,526]	1	hSpCas9	negative selection	4400483
8136421	8136443	19	-	27760321	OCIAML3	viability	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.8599748185552241	[416,370]	[139,207]	-7	hSpCas9	negative selection	4400484
8146204	8146226	19	+	27760321	OCIAML3	viability	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	0.050170045441063404	[153,171]	[119,149]	0	hSpCas9	negative selection	4400485
8117178	8117200	19	-	27760321	OCIAML2	viability	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.0020884786379380404	[297,215]	[140,291]	0	hSpCas9	negative selection	4483944
8126468	8126490	19	+	27760321	OCIAML2	viability	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.36743384503740606	[838,772]	[828,856]	5	hSpCas9	negative selection	4483945
8133050	8133072	19	-	27760321	OCIAML2	viability	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.538972444937037	[484,363]	[385,637]	7	hSpCas9	negative selection	4483946
8136421	8136443	19	-	27760321	OCIAML2	viability	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	0.1588518137503329	[416,370]	[249,493]	2	hSpCas9	negative selection	4483947
8146204	8146226	19	+	27760321	OCIAML2	viability	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	-0.167359944490167	[153,171]	[110,127]	-2	hSpCas9	negative selection	4483948
8117178	8117200	19	-	27760321	MV411	viability	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	-0.07048091678624135	[297,215]	[67,297]	0	hSpCas9	negative selection	4567407
8126468	8126490	19	+	27760321	MV411	viability	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	-0.027215598154718745	[838,772]	[401,701]	0	hSpCas9	negative selection	4567408
8133050	8133072	19	-	27760321	MV411	viability	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	-0.09392024802047166	[484,363]	[95,506]	0	hSpCas9	negative selection	4567409
8136421	8136443	19	-	27760321	MV411	viability	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	0.6507095278708631	[416,370]	[371,460]	5	hSpCas9	negative selection	4567410
8146204	8146226	19	+	27760321	MV411	viability	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	-0.4785965000191279	[153,171]	[76,78]	-3	hSpCas9	negative selection	4567411
8117178	8117200	19	-	27760321	HL60	viability	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	-0.06339126931046735	[297,215]	[196,200]	0	hSpCas9	negative selection	4650870
8126468	8126490	19	+	27760321	HL60	viability	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.8266633038864258	[838,772]	[1337,986]	8	hSpCas9	negative selection	4650871
8133050	8133072	19	-	27760321	HL60	viability	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.3534462064898106	[484,363]	[498,375]	4	hSpCas9	negative selection	4650872
8136421	8136443	19	-	27760321	HL60	viability	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	0.712401030262738	[416,370]	[478,576]	7	hSpCas9	negative selection	4650873
8146204	8146226	19	+	27760321	HL60	viability	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	0.5040838137763003	[153,171]	[266,108]	6	hSpCas9	negative selection	4650874
8117178	8117200	19	-	27760321	HT1080	viability	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	-1.0044877473602032	[215,168]	[21,55]	-4	hSpCas9	negative selection	4734333
8126468	8126490	19	+	27760321	HT1080	viability	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.008644906202880165	[772,602]	[195,362]	0	hSpCas9	negative selection	4734334
8133050	8133072	19	-	27760321	HT1080	viability	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.4279018260569608	[363,283]	[186,158]	2	hSpCas9	negative selection	4734335
8136421	8136443	19	-	27760321	HT1080	viability	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	0.010443055336274237	[370,289]	[29,244]	0	hSpCas9	negative selection	4734336
8146204	8146226	19	+	27760321	HT1080	viability	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	-2.53064515467156	[171,133]	[0,20]	-7	hSpCas9	negative selection	4734337
8117178	8117200	19	-	27760321	HT29	viability after 7 days	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.420289976437391	[215,168]	[210,365,396]	6	hSpCas9	negative selection	4817796
8126468	8126490	19	+	27760321	HT29	viability after 7 days	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.05094038889411323	[772,602]	[1003,897,859]	0	hSpCas9	negative selection	4817797
8133050	8133072	19	-	27760321	HT29	viability after 7 days	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	-0.32987445370068624	[363,283]	[276,376,331]	-5	hSpCas9	negative selection	4817798
8136421	8136443	19	-	27760321	HT29	viability after 7 days	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.025598585622604197	[370,289]	[383,346,512]	0	hSpCas9	negative selection	4817799
8146204	8146226	19	+	27760321	HT29	viability after 7 days	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	-1.2764583050711111	[171,133]	[57,63,116]	-9	hSpCas9	negative selection	4817800
8117178	8117200	19	-	27760321	HT29	viability after 25 days	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.36746859870383086	[215,168]	[303,234,313]	4	hSpCas9	negative selection	4901259
8126468	8126490	19	+	27760321	HT29	viability after 25 days	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.11510267402424246	[772,602]	[737,750,1096]	1	hSpCas9	negative selection	4901260
8133050	8133072	19	-	27760321	HT29	viability after 25 days	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.15100125899398023	[363,283]	[413,351,472]	1	hSpCas9	negative selection	4901261
8136421	8136443	19	-	27760321	HT29	viability after 25 days	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.12869385329689556	[370,289]	[353,425,244]	-1	hSpCas9	negative selection	4901262
8146204	8146226	19	+	27760321	HT29	viability after 25 days	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	0.009166989141438986	[171,133]	[103,209,222]	0	hSpCas9	negative selection	4901263
8117178	8117200	19	-	27760321	HT29	viability after 22 days	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.3050429170256165	[215,168]	[281,344,196]	3	hSpCas9	negative selection	4984722
8126468	8126490	19	+	27760321	HT29	viability after 22 days	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.25609457276214864	[772,602]	[893,896,1060]	2	hSpCas9	negative selection	4984723
8133050	8133072	19	-	27760321	HT29	viability after 22 days	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.4416995692753739	[363,283]	[573,375,574]	5	hSpCas9	negative selection	4984724
8136421	8136443	19	-	27760321	HT29	viability after 22 days	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.36662699837380747	[370,289]	[216,400,272]	-4	hSpCas9	negative selection	4984725
8146204	8146226	19	+	27760321	HT29	viability after 22 days	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	0.42938210266156596	[171,133]	[161,163,391]	4	hSpCas9	negative selection	4984726
8117178	8117200	19	-	27760321	HT29	viability after 19 days	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.0027881195796002345	[215,168]	[264,358,48]	0	hSpCas9	negative selection	5068185
8126468	8126490	19	+	27760321	HT29	viability after 19 days	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.3710237535734855	[772,602]	[1254,967,859]	3	hSpCas9	negative selection	5068186
8133050	8133072	19	-	27760321	HT29	viability after 19 days	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.3187408263725694	[363,283]	[427,449,502]	3	hSpCas9	negative selection	5068187
8136421	8136443	19	-	27760321	HT29	viability after 19 days	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.40319714691072517	[370,289]	[440,210,223]	-4	hSpCas9	negative selection	5068188
8146204	8146226	19	+	27760321	HT29	viability after 19 days	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	-0.3238781745833126	[171,133]	[143,170,105]	-3	hSpCas9	negative selection	5068189
8117178	8117200	19	-	27760321	HT29	viability after 16 days	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	-0.35037363493027907	[215,168]	[209,234,63]	-4	hSpCas9	negative selection	5151648
8126468	8126490	19	+	27760321	HT29	viability after 16 days	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.21193807927843378	[772,602]	[826,979,858]	2	hSpCas9	negative selection	5151649
8133050	8133072	19	-	27760321	HT29	viability after 16 days	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.10226926477946036	[363,283]	[403,491,269]	1	hSpCas9	negative selection	5151650
8136421	8136443	19	-	27760321	HT29	viability after 16 days	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.2556094869560123	[370,289]	[297,313,315]	-3	hSpCas9	negative selection	5151651
8146204	8146226	19	+	27760321	HT29	viability after 16 days	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	-0.33685546826523205	[171,133]	[105,48,250]	-4	hSpCas9	negative selection	5151652
8117178	8117200	19	-	27760321	HT29	viability after 13 days	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.8323103447327838	[215,168]	[739,374,95]	9	hSpCas9	negative selection	5235111
8126468	8126490	19	+	27760321	HT29	viability after 13 days	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.044100519664317384	[772,602]	[606,969,887]	0	hSpCas9	negative selection	5235112
8133050	8133072	19	-	27760321	HT29	viability after 13 days	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	0.3286345630372337	[363,283]	[540,439,436]	4	hSpCas9	negative selection	5235113
8136421	8136443	19	-	27760321	HT29	viability after 13 days	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.1575655906492341	[370,289]	[423,295,312]	-2	hSpCas9	negative selection	5235114
8146204	8146226	19	+	27760321	HT29	viability after 13 days	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	0.009456856744864739	[171,133]	[151,205,177]	0	hSpCas9	negative selection	5235115
8117178	8117200	19	-	27760321	HT29	viability after 10 days	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.6176846521134629	[215,168]	[364,400,341]	8	hSpCas9	negative selection	5318574
8126468	8126490	19	+	27760321	HT29	viability after 10 days	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	0.32205422872826706	[772,602]	[642,1721,878]	4	hSpCas9	negative selection	5318575
8133050	8133072	19	-	27760321	HT29	viability after 10 days	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	-0.06326558560944828	[363,283]	[385,438,338]	-1	hSpCas9	negative selection	5318576
8136421	8136443	19	-	27760321	HT29	viability after 10 days	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.21679788819498896	[370,289]	[464,420,184]	-3	hSpCas9	negative selection	5318577
8146204	8146226	19	+	27760321	HT29	viability after 10 days	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	0.2760254489054128	[171,133]	[165,123,396]	3	hSpCas9	negative selection	5318578
8117178	8117200	19	-	27760321	MOLM13	viability	TCGCTGATGCCCGACGGAAGGG	FBN3	ENSG00000142449	0.057271319777366436	[297,215]	[318,4]	0	hSpCas9	negative selection	5402037
8126468	8126490	19	+	27760321	MOLM13	viability	CGATCTCGCAGCGTTCGCAGGG	FBN3	ENSG00000142449	-0.08313904978434805	[838,772]	[351,494]	0	hSpCas9	negative selection	5402038
8133050	8133072	19	-	27760321	MOLM13	viability	AACGGCGTGTGTCTCAACGAGG	FBN3	ENSG00000142449	-0.2615617649052967	[484,363]	[310,101]	-2	hSpCas9	negative selection	5402039
8136421	8136443	19	-	27760321	MOLM13	viability	TACCGCTGCGAGTGTAACGTGG	FBN3	ENSG00000142449	-0.8951890357342893	[416,370]	[181,65]	-5	hSpCas9	negative selection	5402040
8146204	8146226	19	+	27760321	MOLM13	viability	CCGCAGGCGCGCCTACAGATGG	FBN3	ENSG00000142449	1.2945289923629268	[153,171]	[67,362]	8	hSpCas9	negative selection	5402041
8149061	8149084	19	+	27661255	K562	viability	GCGCCCGGCACGGGGTGTGGAGG	FBN3	ENSG00000142449	-0.11627212141056874	[761,770]	[601,532]	-4	dCas9-KRAB	negative selection	5479613
8149082	8149105	19	+	27661255	K562	viability	GGCTGAGGGCCAAACAGCGAGGG	FBN3	ENSG00000142449	-0.23043553234414826	[38,29]	[28,18]	-6	dCas9-KRAB	negative selection	5479614
8149326	8149349	19	+	27661255	K562	viability	GGCTGCCCGGCTGCGAACAAAGG	FBN3	ENSG00000142449	-0.04108185919444718	[459,374]	[320,328]	-2	dCas9-KRAB	negative selection	5479615
8149490	8149513	19	+	27661255	K562	viability	GCGCGGGACTCAGCGCTGCAGGG	FBN3	ENSG00000142449	0.015562411852161756	[649,788]	[572,583]	0	dCas9-KRAB	negative selection	5479616
8149540	8149563	19	+	27661255	K562	viability	GGCGGGAACGCAAAGCCGAGAGG	FBN3	ENSG00000142449	0.22746355144350755	[948,879]	[904,814]	7	dCas9-KRAB	negative selection	5479617
8146204	8146227	19	-	27260156	BXPC3	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.14625005823925807	[284]	[293,377,311,333]	3	hSpCas9	negative selection	5543110
8147095	8147118	19	+	27260156	BXPC3	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.2961291756926545	[718]	[524,511,714,723]	-6	hSpCas9	negative selection	5543111
8147468	8147491	19	-	27260156	BXPC3	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.06483404858469033	[233]	[214,248,205,268]	-1	hSpCas9	negative selection	5543112
8147172	8147195	19	-	27260156	BXPC3	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.08526312822769389	[219]	[198,140,259,280]	-2	hSpCas9	negative selection	5607374
8147308	8147331	19	+	27260156	BXPC3	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.182909575516492	[1387]	[1414,1495,1854,1878]	4	hSpCas9	negative selection	5607375
8146149	8146172	19	+	27260156	BXPC3	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.8835987558543619	[195]	[114,75,149,103]	-9	hSpCas9	negative selection	5607376
8146204	8146227	19	-	27260156	A673	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.17486343775905266	[284]	[284,265,419,234]	-4	hSpCas9	negative selection	5664361
8147095	8147118	19	+	27260156	A673	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.34048222186541766	[718]	[977,489,670,622]	-7	hSpCas9	negative selection	5664362
8147468	8147491	19	-	27260156	A673	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.30101732728832875	[233]	[224,215,265,202]	-6	hSpCas9	negative selection	5664363
8147172	8147195	19	-	27260156	A673	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.18975698519428486	[219]	[390,282,239,301]	4	hSpCas9	negative selection	5728625
8147308	8147331	19	+	27260156	A673	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.09471263273353436	[1387]	[2213,1494,1606,1862]	2	hSpCas9	negative selection	5728626
8146149	8146172	19	+	27260156	A673	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.38923950466283563	[195]	[236,184,143,157]	-7	hSpCas9	negative selection	5728627
8146204	8146227	19	-	27260156	A375	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.2384464490689603	[284]	[272,345,277,243]	-3	hSpCas9	negative selection	5785612
8147095	8147118	19	+	27260156	A375	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.4615842327502504	[718]	[612,718,637,495]	-6	hSpCas9	negative selection	5785613
8147468	8147491	19	-	27260156	A375	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.4001272143404935	[233]	[220,315,219,98]	-5	hSpCas9	negative selection	5785614
8147172	8147195	19	-	27260156	A375	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.06424724594685882	[219]	[488,257,226,117]	0	hSpCas9	negative selection	5849876
8147308	8147331	19	+	27260156	A375	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.4301335100445338	[1387]	[2039,2400,2171,2148]	6	hSpCas9	negative selection	5849877
8146149	8146172	19	+	27260156	A375	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.8106154907021197	[195]	[118,167,111,127]	-8	hSpCas9	negative selection	5849878
8146204	8146227	19	-	27260156	COLO741	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.15704511316280068	[284]	[356,359,268]	-3	hSpCas9	negative selection	5906863
8147095	8147118	19	+	27260156	COLO741	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.5295543966413953	[718]	[735,639,546]	-8	hSpCas9	negative selection	5906864
8147468	8147491	19	-	27260156	COLO741	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.21755713515601105	[233]	[313,224,237]	-5	hSpCas9	negative selection	5906865
8147172	8147195	19	-	27260156	COLO741	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.08902863297421404	[219]	[481,221,213]	2	hSpCas9	negative selection	5971127
8147308	8147331	19	+	27260156	COLO741	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.20032536478067953	[1387]	[2198,2279,1670]	4	hSpCas9	negative selection	5971128
8146149	8146172	19	+	27260156	COLO741	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.7571249835499954	[195]	[166,161,118]	-9	hSpCas9	negative selection	5971129
8146204	8146227	19	-	27260156	CAL120	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.5218530438557326	[284]	[310,273,166]	-6	hSpCas9	negative selection	6028114
8147095	8147118	19	+	27260156	CAL120	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.06870999512948728	[718]	[599,1130,790]	-1	hSpCas9	negative selection	6028115
8147468	8147491	19	-	27260156	CAL120	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.15922504372570656	[233]	[339,299,155]	-2	hSpCas9	negative selection	6028116
8147172	8147195	19	-	27260156	CAL120	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.51980602376855	[219]	[272,115,195]	-6	hSpCas9	negative selection	6092378
8147308	8147331	19	+	27260156	CAL120	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.37211648456856405	[1387]	[3410,1835,1645]	5	hSpCas9	negative selection	6092379
8146149	8146172	19	+	27260156	CAL120	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.5277515450780395	[195]	[150,87,263]	-6	hSpCas9	negative selection	6092380
8146204	8146227	19	-	27260156	CADOES1	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.10588123545481176	[284]	[275,275,192,239]	-2	hSpCas9	negative selection	6149365
8147095	8147118	19	+	27260156	CADOES1	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.7260469451120106	[718]	[560,376,367,306]	-8	hSpCas9	negative selection	6149366
8147468	8147491	19	-	27260156	CADOES1	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.5036013999430424	[233]	[123,144,167,177]	-7	hSpCas9	negative selection	6149367
8147172	8147195	19	-	27260156	CADOES1	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.0032804458339343867	[219]	[239,161,190,227]	0	hSpCas9	negative selection	6213629
8147308	8147331	19	+	27260156	CADOES1	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.14789116850357398	[1387]	[1263,1319,1457,1688]	2	hSpCas9	negative selection	6213630
8146149	8146172	19	+	27260156	CADOES1	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.8315800082452678	[195]	[102,96,99,109]	-9	hSpCas9	negative selection	6213631
8146204	8146227	19	-	27260156	EWS502	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.1439709858317908	[284]	[311,211,509,306]	2	hSpCas9	negative selection	6270616
8147095	8147118	19	+	27260156	EWS502	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.6119832825803762	[718]	[499,487,512,489]	-7	hSpCas9	negative selection	6270617
8147468	8147491	19	-	27260156	EWS502	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.14560212267860018	[233]	[227,178,286,201]	-3	hSpCas9	negative selection	6270618
8147172	8147195	19	-	27260156	EWS502	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.02856406964933189	[219]	[336,188,220,188]	0	hSpCas9	negative selection	6334880
8147308	8147331	19	+	27260156	EWS502	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.21509591515294368	[1387]	[1820,1736,1519,1724]	4	hSpCas9	negative selection	6334881
8146149	8146172	19	+	27260156	EWS502	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-1.2987968435283581	[195]	[76,91,96,70]	-9	hSpCas9	negative selection	6334882
8146204	8146227	19	-	27260156	EW8	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.5631672346426532	[284]	[217,153,118,146]	-8	hSpCas9	negative selection	6391867
8147095	8147118	19	+	27260156	EW8	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.38320211003721694	[718]	[543,506,369,388]	-6	hSpCas9	negative selection	6391868
8147468	8147491	19	-	27260156	EW8	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	0.24087914406485122	[233]	[158,107,322,280]	4	hSpCas9	negative selection	6391869
8147172	8147195	19	-	27260156	EW8	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.014813167525046689	[219]	[165,228,167,142]	0	hSpCas9	negative selection	6456131
8147308	8147331	19	+	27260156	EW8	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.24239816618383236	[1387]	[1773,1019,1110,1497]	4	hSpCas9	negative selection	6456132
8146149	8146172	19	+	27260156	EW8	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.6024290305824873	[195]	[116,81,82,140]	-8	hSpCas9	negative selection	6456133
8146204	8146227	19	-	27260156	CORL105	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.4624058126165177	[284]	[219,192,376,199]	-7	hSpCas9	negative selection	6513118
8147095	8147118	19	+	27260156	CORL105	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.49641777902231315	[718]	[555,527,621,683]	-7	hSpCas9	negative selection	6513119
8147468	8147491	19	-	27260156	CORL105	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.6410212263279917	[233]	[149,254,141,147]	-8	hSpCas9	negative selection	6513120
8147172	8147195	19	-	27260156	CORL105	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.3088498865652919	[219]	[371,290,315,298]	6	hSpCas9	negative selection	6577382
8147308	8147331	19	+	27260156	CORL105	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.28624662884690677	[1387]	[1860,1796,2502,1845]	5	hSpCas9	negative selection	6577383
8146149	8146172	19	+	27260156	CORL105	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.889721175448059	[195]	[157,173,80,75]	-9	hSpCas9	negative selection	6577384
8146204	8146227	19	-	27260156	HS294T	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.0004135523104988881	[284]	[145,66,107,118]	0	hSpCas9	negative selection	6634369
8147095	8147118	19	+	27260156	HS294T	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.35700019630102714	[718]	[201,220,197,253]	-5	hSpCas9	negative selection	6634370
8147468	8147491	19	-	27260156	HS294T	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.41351397552718216	[233]	[60,43,109,55]	-5	hSpCas9	negative selection	6634371
8147172	8147195	19	-	27260156	HS294T	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.15092661933992346	[219]	[43,74,90,103]	-2	hSpCas9	negative selection	6698633
8147308	8147331	19	+	27260156	HS294T	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.19072656499838048	[1387]	[548,635,572,711]	2	hSpCas9	negative selection	6698634
8146149	8146172	19	+	27260156	HS294T	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.8650792709051462	[195]	[37,48,366,104]	9	hSpCas9	negative selection	6698635
8146204	8146227	19	-	27260156	HCC44	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.28056856668151503	[284]	[455,361,371,379]	4	hSpCas9	negative selection	6755620
8147095	8147118	19	+	27260156	HCC44	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.30652719135234	[718]	[825,420,826,629]	-5	hSpCas9	negative selection	6755621
8147468	8147491	19	-	27260156	HCC44	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.03822828713202697	[233]	[215,286,223,286]	0	hSpCas9	negative selection	6755622
8147172	8147195	19	-	27260156	HCC44	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.13302588171060314	[219]	[259,174,342,333]	2	hSpCas9	negative selection	6819884
8147308	8147331	19	+	27260156	HCC44	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.11704350501820326	[1387]	[2240,1329,1788,1557]	1	hSpCas9	negative selection	6819885
8146149	8146172	19	+	27260156	HCC44	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.4215897938953328	[195]	[155,70,207,242]	-6	hSpCas9	negative selection	6819886
8146204	8146227	19	-	27260156	G402	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.3428843169054675	[284]	[282,179,279,344]	-4	hSpCas9	negative selection	6876871
8147095	8147118	19	+	27260156	G402	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.2771189559268193	[718]	[500,666,1014,676]	-3	hSpCas9	negative selection	6876872
8147468	8147491	19	-	27260156	G402	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	0.3531911531974613	[233]	[410,180,125,717]	4	hSpCas9	negative selection	6876873
8147172	8147195	19	-	27260156	G402	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.1266295989501779	[219]	[674,311,65,179]	1	hSpCas9	negative selection	6941135
8147308	8147331	19	+	27260156	G402	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.3540245066763814	[1387]	[2910,2220,1838,1807]	4	hSpCas9	negative selection	6941136
8146149	8146172	19	+	27260156	G402	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.9416828409969118	[195]	[26,71,162,213]	-8	hSpCas9	negative selection	6941137
8146204	8146227	19	-	27260156	L33	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.13700469445166774	[284]	[285,154,201,268]	3	hSpCas9	negative selection	6998122
8147095	8147118	19	+	27260156	L33	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.25516669236421274	[718]	[554,239,437,573]	-5	hSpCas9	negative selection	6998123
8147468	8147491	19	-	27260156	L33	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	0.04651848420678073	[233]	[222,69,145,339]	1	hSpCas9	negative selection	6998124
8147172	8147195	19	-	27260156	L33	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.6707861995642048	[219]	[324,182,190,325]	9	hSpCas9	negative selection	7062386
8147308	8147331	19	+	27260156	L33	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	-0.03854663935303715	[1387]	[1242,617,856,1293]	-1	hSpCas9	negative selection	7062387
8146149	8146172	19	+	27260156	L33	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.9315870195587328	[195]	[95,27,43,175]	-9	hSpCas9	negative selection	7062388
8146204	8146227	19	-	27260156	K562	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.018420822527718483	[284]	[362,109,279,269]	0	hSpCas9	negative selection	7119373
8147095	8147118	19	+	27260156	K562	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.4219132599640142	[718]	[892,378,437,248]	-5	hSpCas9	negative selection	7119374
8147468	8147491	19	-	27260156	K562	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-1.0153291878184574	[233]	[99,77,137,93]	-8	hSpCas9	negative selection	7119375
8147172	8147195	19	-	27260156	K562	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.26039077744881345	[219]	[361,235,329,39]	3	hSpCas9	negative selection	7183637
8147308	8147331	19	+	27260156	K562	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.3527477447614049	[1387]	[2296,1410,1688,1005]	4	hSpCas9	negative selection	7183638
8146149	8146172	19	+	27260156	K562	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-1.6603349895763797	[195]	[101,18,37,61]	-9	hSpCas9	negative selection	7183639
8146204	8146227	19	-	27260156	HT29	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.0030255293049412657	[284]	[367,315,362,333]	0	hSpCas9	negative selection	7240624
8147095	8147118	19	+	27260156	HT29	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.362295194220649	[718]	[713,721,712,583]	-6	hSpCas9	negative selection	7240625
8147468	8147491	19	-	27260156	HT29	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.11257591254091337	[233]	[450,248,183,188]	-2	hSpCas9	negative selection	7240626
8147172	8147195	19	-	27260156	HT29	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.23062782363390233	[219]	[358,354,268,280]	4	hSpCas9	negative selection	7304888
8147308	8147331	19	+	27260156	HT29	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.0587970120339909	[1387]	[1797,2196,1674,1428]	1	hSpCas9	negative selection	7304889
8146149	8146172	19	+	27260156	HT29	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.8587245378792416	[195]	[116,206,47,154]	-8	hSpCas9	negative selection	7304890
8146204	8146227	19	-	27260156	MHHES1	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.03688927283501009	[284]	[323,338,343,307]	0	hSpCas9	negative selection	7361875
8147095	8147118	19	+	27260156	MHHES1	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.2255042713508309	[718]	[575,697,545,875]	-4	hSpCas9	negative selection	7361876
8147468	8147491	19	-	27260156	MHHES1	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.42563286080609775	[233]	[223,126,184,231]	-7	hSpCas9	negative selection	7361877
8147172	8147195	19	-	27260156	MHHES1	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.28816024189205647	[219]	[276,349,301,280]	5	hSpCas9	negative selection	7426139
8147308	8147331	19	+	27260156	MHHES1	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.24286310834568825	[1387]	[2070,1951,1866,1569]	4	hSpCas9	negative selection	7426140
8146149	8146172	19	+	27260156	MHHES1	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.771999462082571	[195]	[104,174,168,78]	-8	hSpCas9	negative selection	7426141
8146204	8146227	19	-	27260156	MEWO	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.012081339085438736	[284]	[321,240,253]	0	hSpCas9	negative selection	7483126
8147095	8147118	19	+	27260156	MEWO	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.3177251234167533	[718]	[664,594,382]	-6	hSpCas9	negative selection	7483127
8147468	8147491	19	-	27260156	MEWO	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.1731263746932381	[233]	[216,168,200]	-4	hSpCas9	negative selection	7483128
8147172	8147195	19	-	27260156	MEWO	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.0522405039320708	[219]	[185,188,259]	1	hSpCas9	negative selection	7547390
8147308	8147331	19	+	27260156	MEWO	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.04526496938199576	[1387]	[1579,1145,1340]	1	hSpCas9	negative selection	7547391
8146149	8146172	19	+	27260156	MEWO	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.4827231874601139	[195]	[198,84,122]	-8	hSpCas9	negative selection	7547392
8146204	8146227	19	-	27260156	LNCAPCLONEFGC	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.3384468187529489	[284]	[108,190,383,161]	-5	hSpCas9	negative selection	7604377
8147095	8147118	19	+	27260156	LNCAPCLONEFGC	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.3314327831607294	[718]	[350,507,786,467]	-5	hSpCas9	negative selection	7604378
8147468	8147491	19	-	27260156	LNCAPCLONEFGC	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.4450913322504648	[233]	[142,177,192,112]	-6	hSpCas9	negative selection	7604379
8147172	8147195	19	-	27260156	LNCAPCLONEFGC	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.32723793555638525	[219]	[147,346,286,218]	5	hSpCas9	negative selection	7668641
8147308	8147331	19	+	27260156	LNCAPCLONEFGC	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.349908691133177	[1387]	[1578,1453,1858,1564]	5	hSpCas9	negative selection	7668642
8146149	8146172	19	+	27260156	LNCAPCLONEFGC	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-1.0736082172513473	[195]	[106,72,72,82]	-9	hSpCas9	negative selection	7668643
8146204	8146227	19	-	27260156	PANC0327	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.11439655898691237	[284]	[206,173,289,269]	-2	hSpCas9	negative selection	7725628
8147095	8147118	19	+	27260156	PANC0327	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.44169742190781014	[718]	[554,683,290,329]	-6	hSpCas9	negative selection	7725629
8147468	8147491	19	-	27260156	PANC0327	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	0.13352610913763518	[233]	[282,347,160,108]	2	hSpCas9	negative selection	7725630
8147172	8147195	19	-	27260156	PANC0327	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.23093570184683399	[219]	[230,324,142,205]	3	hSpCas9	negative selection	7789892
8147308	8147331	19	+	27260156	PANC0327	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.3410536022852104	[1387]	[1885,1268,1554,1600]	5	hSpCas9	negative selection	7789893
8146149	8146172	19	+	27260156	PANC0327	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.4176270012420573	[195]	[221,73,65,173]	-6	hSpCas9	negative selection	7789894
8146204	8146227	19	-	27260156	NCIH2009	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.029801342286177035	[284]	[421,378,374]	0	hSpCas9	negative selection	7846879
8147095	8147118	19	+	27260156	NCIH2009	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.4142839490364175	[718]	[878,692,713]	-5	hSpCas9	negative selection	7846880
8147468	8147491	19	-	27260156	NCIH2009	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-1.2977249599780516	[233]	[236,93,88]	-8	hSpCas9	negative selection	7846881
8147172	8147195	19	-	27260156	NCIH2009	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.22407275686253125	[219]	[396,411,273]	3	hSpCas9	negative selection	7911143
8147308	8147331	19	+	27260156	NCIH2009	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.40307156049881687	[1387]	[2899,3166,1676]	5	hSpCas9	negative selection	7911144
8146149	8146172	19	+	27260156	NCIH2009	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.8367522668977921	[195]	[417,840,186]	9	hSpCas9	negative selection	7911145
8146204	8146227	19	-	27260156	NCIH1373	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.9809042057177727	[284]	[165,164,155,41]	-7	hSpCas9	negative selection	7968130
8147095	8147118	19	+	27260156	NCIH1373	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.6679137244315182	[718]	[764,348,439,139]	-6	hSpCas9	negative selection	7968131
8147468	8147491	19	-	27260156	NCIH1373	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.569883363091106	[233]	[394,78,186,21]	-5	hSpCas9	negative selection	7968132
8147172	8147195	19	-	27260156	NCIH1373	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.4128914262349018	[219]	[598,236,314,53]	4	hSpCas9	negative selection	8032394
8147308	8147331	19	+	27260156	NCIH1373	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.5638654707014576	[1387]	[2771,2000,2327,573]	5	hSpCas9	negative selection	8032395
8146149	8146172	19	+	27260156	NCIH1373	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.9543754700474669	[195]	[214,48,90,31]	-7	hSpCas9	negative selection	8032396
8146204	8146227	19	-	27260156	PATU8902	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.9293044567113634	[284]	[323,248,161,93]	-7	hSpCas9	negative selection	8089381
8147095	8147118	19	+	27260156	PATU8902	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.4224686170707876	[718]	[456,716,824,996]	-4	hSpCas9	negative selection	8089382
8147468	8147491	19	-	27260156	PATU8902	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-1.7516162709421688	[233]	[44,109,173,29]	-8	hSpCas9	negative selection	8089383
8147172	8147195	19	-	27260156	PATU8902	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.3533822352687279	[219]	[395,316,119,141]	-4	hSpCas9	negative selection	8153645
8147308	8147331	19	+	27260156	PATU8902	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.7537637324290958	[1387]	[3060,3102,2857,4209]	7	hSpCas9	negative selection	8153646
8146149	8146172	19	+	27260156	PATU8902	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.6051586606707482	[195]	[46,179,65,491]	-5	hSpCas9	negative selection	8153647
8146204	8146227	19	-	27260156	PANC1	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.0503296065548422	[284]	[213,236,278,215]	-1	hSpCas9	negative selection	8210632
8147095	8147118	19	+	27260156	PANC1	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.5868291149492256	[718]	[479,468,378,332]	-7	hSpCas9	negative selection	8210633
8147468	8147491	19	-	27260156	PANC1	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.2659451093439922	[233]	[166,205,149,152]	-4	hSpCas9	negative selection	8210634
8147172	8147195	19	-	27260156	PANC1	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.11608945295878548	[219]	[190,232,174,219]	1	hSpCas9	negative selection	8274896
8147308	8147331	19	+	27260156	PANC1	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.41872081790011495	[1387]	[1643,1887,1811,1140]	6	hSpCas9	negative selection	8274897
8146149	8146172	19	+	27260156	PANC1	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.46652228023774267	[195]	[118,148,95,125]	-6	hSpCas9	negative selection	8274898
8146204	8146227	19	-	27260156	PANC0813	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.31367529290683127	[284]	[327,226,165,355]	-5	hSpCas9	negative selection	8331883
8147095	8147118	19	+	27260156	PANC0813	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.2947019650541534	[718]	[806,687,538,726]	-5	hSpCas9	negative selection	8331884
8147468	8147491	19	-	27260156	PANC0813	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.34670918716785826	[233]	[261,215,220,171]	-5	hSpCas9	negative selection	8331885
8147172	8147195	19	-	27260156	PANC0813	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.19797629954398688	[219]	[320,299,314,253]	3	hSpCas9	negative selection	8396147
8147308	8147331	19	+	27260156	PANC0813	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.3190757688215078	[1387]	[2269,1839,2175,1877]	5	hSpCas9	negative selection	8396148
8146149	8146172	19	+	27260156	PANC0813	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.8795636991513738	[195]	[84,67,113,223]	-8	hSpCas9	negative selection	8396149
8146204	8146227	19	-	27260156	RDES	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.19744074348696472	[284]	[240,261,369,274]	-3	hSpCas9	negative selection	8453134
8147095	8147118	19	+	27260156	RDES	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.4345785817670056	[718]	[412,590,730,768]	-6	hSpCas9	negative selection	8453135
8147468	8147491	19	-	27260156	RDES	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.1892172052589305	[233]	[335,179,184,210]	-3	hSpCas9	negative selection	8453136
8147172	8147195	19	-	27260156	RDES	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.06228314867483764	[219]	[186,224,264,309]	-1	hSpCas9	negative selection	8517398
8147308	8147331	19	+	27260156	RDES	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.302682040823292	[1387]	[1641,2100,1976,2183]	5	hSpCas9	negative selection	8517399
8146149	8146172	19	+	27260156	RDES	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.6648249104382666	[195]	[169,131,134,116]	-8	hSpCas9	negative selection	8517400
8146204	8146227	19	-	27260156	PC3	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.27472996450558573	[284]	[135,185,275,388]	-6	hSpCas9	negative selection	8574385
8147095	8147118	19	+	27260156	PC3	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.4884660418011798	[718]	[191,475,980,695]	-8	hSpCas9	negative selection	8574386
8147468	8147491	19	-	27260156	PC3	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.7721296921236116	[233]	[42,182,231,156]	-9	hSpCas9	negative selection	8574387
8147172	8147195	19	-	27260156	PC3	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.16216128183157874	[219]	[107,217,483,311]	3	hSpCas9	negative selection	8638649
8147308	8147331	19	+	27260156	PC3	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	-0.08474919677569925	[1387]	[907,1167,2127,1380]	-2	hSpCas9	negative selection	8638650
8146149	8146172	19	+	27260156	PC3	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.7686954132169137	[195]	[44,101,220,157]	-9	hSpCas9	negative selection	8638651
8146204	8146227	19	-	27260156	PATU8988T	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.23036326586344746	[284]	[94,153,468,207]	-4	hSpCas9	negative selection	8695636
8147095	8147118	19	+	27260156	PATU8988T	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.316245335277146	[718]	[573,410,512,734]	-5	hSpCas9	negative selection	8695637
8147468	8147491	19	-	27260156	PATU8988T	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.1610784406753687	[233]	[117,132,340,208]	-3	hSpCas9	negative selection	8695638
8147172	8147195	19	-	27260156	PATU8988T	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.2329657575436883	[219]	[178,122,188,230]	-4	hSpCas9	negative selection	8759900
8147308	8147331	19	+	27260156	PATU8988T	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.1649740658343728	[1387]	[1640,1254,1297,1825]	3	hSpCas9	negative selection	8759901
8146149	8146172	19	+	27260156	PATU8988T	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-1.104202622537207	[195]	[115,54,33,149]	-9	hSpCas9	negative selection	8759902
8146204	8146227	19	-	27260156	T47D	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.16911243373466756	[284]	[317,235,309,322]	-4	hSpCas9	negative selection	8816887
8147095	8147118	19	+	27260156	T47D	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.41441204060589465	[718]	[644,532,709,632]	-7	hSpCas9	negative selection	8816888
8147468	8147491	19	-	27260156	T47D	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.33464291733988194	[233]	[243,212,199,207]	-6	hSpCas9	negative selection	8816889
8147172	8147195	19	-	27260156	T47D	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.2628846943105311	[219]	[282,383,231,325]	5	hSpCas9	negative selection	8881151
8147308	8147331	19	+	27260156	T47D	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.20649034229678498	[1387]	[1852,1791,1927,1895]	4	hSpCas9	negative selection	8881152
8146149	8146172	19	+	27260156	T47D	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.8546147324629634	[195]	[102,140,103,156]	-9	hSpCas9	negative selection	8881153
8146204	8146227	19	-	27260156	SU8686	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.022454318726007894	[284]	[198,334,256,328]	0	hSpCas9	negative selection	8938138
8147095	8147118	19	+	27260156	SU8686	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.2563726638953589	[718]	[487,581,757,568]	-4	hSpCas9	negative selection	8938139
8147468	8147491	19	-	27260156	SU8686	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	0.12411763713475354	[233]	[156,287,317,254]	2	hSpCas9	negative selection	8938140
8147172	8147195	19	-	27260156	SU8686	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.2926309853151756	[219]	[296,230,285,251]	5	hSpCas9	negative selection	9002402
8147308	8147331	19	+	27260156	SU8686	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.16764395217023442	[1387]	[1436,1425,1474,1919]	3	hSpCas9	negative selection	9002403
8146149	8146172	19	+	27260156	SU8686	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.9589799697667045	[195]	[89,62,125,131]	-8	hSpCas9	negative selection	9002404
8146204	8146227	19	-	27260156	SKES1	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.07562720328589012	[284]	[279,341,295,178]	-2	hSpCas9	negative selection	9059389
8147095	8147118	19	+	27260156	SKES1	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.33164331708720285	[718]	[539,752,467,535]	-6	hSpCas9	negative selection	9059390
8147468	8147491	19	-	27260156	SKES1	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.6145745341539721	[233]	[211,110,97,186]	-8	hSpCas9	negative selection	9059391
8147172	8147195	19	-	27260156	SKES1	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.3439792649218154	[219]	[273,325,291,229]	7	hSpCas9	negative selection	9123653
8147308	8147331	19	+	27260156	SKES1	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.26317208162792505	[1387]	[1861,1829,1333,1655]	5	hSpCas9	negative selection	9123654
8146149	8146172	19	+	27260156	SKES1	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.3923418066893951	[195]	[109,273,134,91]	-7	hSpCas9	negative selection	9123655
8146204	8146227	19	-	27260156	TOV112D	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.5232137011912231	[284]	[113,235,239,205]	-8	hSpCas9	negative selection	9180640
8147095	8147118	19	+	27260156	TOV112D	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.39750240240597207	[718]	[486,660,406,650]	-7	hSpCas9	negative selection	9180641
8147468	8147491	19	-	27260156	TOV112D	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.33862180891356286	[233]	[103,226,139,270]	-6	hSpCas9	negative selection	9180642
8147172	8147195	19	-	27260156	TOV112D	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	-0.22000087995889706	[219]	[197,91,245,196]	-4	hSpCas9	negative selection	9244904
8147308	8147331	19	+	27260156	TOV112D	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.22952372522069342	[1387]	[2028,1938,1082,1576]	4	hSpCas9	negative selection	9244905
8146149	8146172	19	+	27260156	TOV112D	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.7873021641003048	[195]	[110,150,97,103]	-9	hSpCas9	negative selection	9244906
8146204	8146227	19	-	27260156	TC71	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	0.11759248990671123	[284]	[328,346,330,317]	3	hSpCas9	negative selection	9301891
8147095	8147118	19	+	27260156	TC71	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.5595136985038358	[718]	[512,574,465,540]	-9	hSpCas9	negative selection	9301892
8147468	8147491	19	-	27260156	TC71	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.1507174633714392	[233]	[150,284,241,226]	-4	hSpCas9	negative selection	9301893
8147172	8147195	19	-	27260156	TC71	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.2902859366306537	[219]	[319,267,248,318]	7	hSpCas9	negative selection	9366155
8147308	8147331	19	+	27260156	TC71	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.08523431169398044	[1387]	[1418,1590,1467,1859]	2	hSpCas9	negative selection	9366156
8146149	8146172	19	+	27260156	TC71	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.4071804184338743	[195]	[187,117,125,204]	-8	hSpCas9	negative selection	9366157
8146204	8146227	19	-	27260156	TC32	viability	GCCATCTGTAGGCGCGCCTGCGG	FBN3	ENSG00000142449	-0.04669200141990559	[284]	[166,247,302,330]	-1	hSpCas9	negative selection	9423142
8147095	8147118	19	+	27260156	TC32	viability	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.11918969450170536	[718]	[527,535,711,740]	-2	hSpCas9	negative selection	9423143
8147468	8147491	19	-	27260156	TC32	viability	GGGACACGCCATGACTCTGGAGG	FBN3	ENSG00000142449	-0.21255196282348954	[233]	[194,124,340,133]	-4	hSpCas9	negative selection	9423144
8147172	8147195	19	-	27260156	TC32	viability	CCCCGAAGGCCGAATGTGTGCGG	FBN3	ENSG00000142449	0.15895596734264517	[219]	[187,199,271,275]	3	hSpCas9	negative selection	9487406
8147308	8147331	19	+	27260156	TC32	viability	ACGCACCCCTGCAAGATGCCTGG	FBN3	ENSG00000142449	0.37276174393616013	[1387]	[1532,1066,2500,1971]	6	hSpCas9	negative selection	9487407
8146149	8146172	19	+	27260156	TC32	viability	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.9401764692366004	[195]	[45,35,152,188]	-9	hSpCas9	negative selection	9487408
8141726	8141749	19	+	27869803	HPAFII	viability after 27 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	-0.13136065197720337	[460]	[241,203,NaN]	-1	hSpCas9	negative selection	9570741
8142057	8142080	19	-	27869803	HPAFII	viability after 27 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.24680813749404018	[205]	[63,113,NaN]	-2	hSpCas9	negative selection	9570742
8144893	8144916	19	+	27869803	HPAFII	viability after 27 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.297871570824465	[575]	[410,339,NaN]	2	hSpCas9	negative selection	9570743
8145870	8145893	19	-	27869803	HPAFII	viability after 27 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	1.3796560594172949	[103]	[180,109,NaN]	9	hSpCas9	negative selection	9570744
8146149	8146172	19	+	27869803	HPAFII	viability after 27 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.6324804403730162	[401]	[373,288,NaN]	5	hSpCas9	negative selection	9570745
8147095	8147118	19	+	27869803	HPAFII	viability after 27 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.31337113865408583	[210]	[43,126,NaN]	-2	hSpCas9	negative selection	9570746
8141726	8141749	19	+	27869803	HPAFII	viability after 15 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	-0.39468368184814956	[460]	[559,262,NaN]	-4	hSpCas9	negative selection	9653190
8142057	8142080	19	-	27869803	HPAFII	viability after 15 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.1343342430856584	[205]	[308,134,NaN]	-1	hSpCas9	negative selection	9653191
8144893	8144916	19	+	27869803	HPAFII	viability after 15 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.08618776534615957	[575]	[1044,415,NaN]	1	hSpCas9	negative selection	9653192
8145870	8145893	19	-	27869803	HPAFII	viability after 15 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	1.661966965622033	[103]	[349,355,NaN]	9	hSpCas9	negative selection	9653193
8146149	8146172	19	+	27869803	HPAFII	viability after 15 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.20897805783105217	[401]	[848,281,NaN]	2	hSpCas9	negative selection	9653194
8147095	8147118	19	+	27869803	HPAFII	viability after 15 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	0.15658961178431868	[210]	[253,251,NaN]	1	hSpCas9	negative selection	9653195
8141726	8141749	19	+	27869803	ASPC1	viability after 36 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.9226732263648849	[1068]	[1213,673,370]	8	hSpCas9	negative selection	9735639
8142057	8142080	19	-	27869803	ASPC1	viability after 36 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.245074432903443	[303]	[130,127,118]	2	hSpCas9	negative selection	9735640
8144893	8144916	19	+	27869803	ASPC1	viability after 36 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.2654879177874676	[1252]	[664,499,442]	2	hSpCas9	negative selection	9735641
8145870	8145893	19	-	27869803	ASPC1	viability after 36 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.5157700674573729	[330]	[73,229,175]	5	hSpCas9	negative selection	9735642
8146149	8146172	19	+	27869803	ASPC1	viability after 36 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.25194537259381256	[1180]	[439,585,445]	2	hSpCas9	negative selection	9735643
8147095	8147118	19	+	27869803	ASPC1	viability after 36 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	0.42595935006742114	[568]	[307,227,265]	4	hSpCas9	negative selection	9735644
8141726	8141749	19	+	27869803	PATU8988S	viability after 35 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.5168118495547287	[889]	[452,572,NaN]	6	hSpCas9	negative selection	9818088
8142057	8142080	19	-	27869803	PATU8988S	viability after 35 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.5552661221401245	[417]	[143,84,NaN]	-5	hSpCas9	negative selection	9818089
8144893	8144916	19	+	27869803	PATU8988S	viability after 35 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.13574605538235063	[1157]	[467,556,NaN]	1	hSpCas9	negative selection	9818090
8145870	8145893	19	-	27869803	PATU8988S	viability after 35 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.18809017176700737	[265]	[143,99,NaN]	2	hSpCas9	negative selection	9818091
8146149	8146172	19	+	27869803	PATU8988S	viability after 35 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.4196033098077566	[1125]	[359,317,NaN]	-4	hSpCas9	negative selection	9818092
8147095	8147118	19	+	27869803	PATU8988S	viability after 35 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	0.026538040405536027	[556]	[226,229,NaN]	0	hSpCas9	negative selection	9818093
8141726	8141749	19	+	27869803	PATU8988S	viability after 31 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.634084689785541	[889]	[548,552,NaN]	7	hSpCas9	negative selection	9900537
8142057	8142080	19	-	27869803	PATU8988S	viability after 31 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	-0.5545884701559409	[417]	[116,108,NaN]	-6	hSpCas9	negative selection	9900538
8144893	8144916	19	+	27869803	PATU8988S	viability after 31 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.27951023502537886	[1157]	[453,695,NaN]	3	hSpCas9	negative selection	9900539
8145870	8145893	19	-	27869803	PATU8988S	viability after 31 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	0.680575692086516	[265]	[169,169,NaN]	7	hSpCas9	negative selection	9900540
8146149	8146172	19	+	27869803	PATU8988S	viability after 31 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	-0.42855432592903464	[1125]	[132,588,NaN]	-5	hSpCas9	negative selection	9900541
8147095	8147118	19	+	27869803	PATU8988S	viability after 31 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.5478922960593752	[556]	[154,147,NaN]	-6	hSpCas9	negative selection	9900542
8141726	8141749	19	+	27869803	HPAFII	viability after 35 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.48291075556662133	[460]	[177,492,NaN]	3	hSpCas9	negative selection	9982986
8142057	8142080	19	-	27869803	HPAFII	viability after 35 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.33942044057110843	[205]	[146,114,NaN]	2	hSpCas9	negative selection	9982987
8144893	8144916	19	+	27869803	HPAFII	viability after 35 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.7047393640756368	[575]	[407,550,NaN]	4	hSpCas9	negative selection	9982988
8145870	8145893	19	-	27869803	HPAFII	viability after 35 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	1.9089015393051731	[103]	[208,184,NaN]	9	hSpCas9	negative selection	9982989
8146149	8146172	19	+	27869803	HPAFII	viability after 35 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	1.6506465143331666	[401]	[463,835,NaN]	9	hSpCas9	negative selection	9982990
8147095	8147118	19	+	27869803	HPAFII	viability after 35 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.7949670416845255	[210]	[14,113,NaN]	-5	hSpCas9	negative selection	9982991
8141726	8141749	19	+	27869803	HPAFII	viability after 31 days	CGGCGCTGCTGTCACTGAGCCGG	FBN3	ENSG00000142449	0.2967884241348354	[460]	[268,370,NaN]	2	hSpCas9	negative selection	10065435
8142057	8142080	19	-	27869803	HPAFII	viability after 31 days	GACGGGCCTCGTGTGCACCAAGG	FBN3	ENSG00000142449	0.20021478304642293	[205]	[139,124,NaN]	1	hSpCas9	negative selection	10065436
8144893	8144916	19	+	27869803	HPAFII	viability after 31 days	TCCCATGAAGCCATACACACAGG	FBN3	ENSG00000142449	0.38810621365897124	[575]	[356,494,NaN]	3	hSpCas9	negative selection	10065437
8145870	8145893	19	-	27869803	HPAFII	viability after 31 days	GGCGTCCTGTCTGTGTCAGAAGG	FBN3	ENSG00000142449	2.1994435749662733	[103]	[280,253,NaN]	9	hSpCas9	negative selection	10065438
8146149	8146172	19	+	27869803	HPAFII	viability after 31 days	AGCCAGCGTCCCATCCGCACAGG	FBN3	ENSG00000142449	0.9689625406674758	[401]	[432,450,NaN]	7	hSpCas9	negative selection	10065439
8147095	8147118	19	+	27869803	HPAFII	viability after 31 days	AGCACTCACGTACGACACACTGG	FBN3	ENSG00000142449	-0.34502773388502994	[210]	[75,111,NaN]	-2	hSpCas9	negative selection	10065440
8141961	8141984	19	+	28162770	P31FUJ	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.06348400721580005	[192]	[236]	0	hSpCas9	negative selection	10155693
8136434	8136457	19	+	28162770	P31FUJ	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.217120582182109	[182]	[184]	-2	hSpCas9	negative selection	10155694
8095979	8096002	19	+	28162770	P31FUJ	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	0.24896140866527844	[168]	[235]	2	hSpCas9	negative selection	10155695
8085540	8085563	19	-	28162770	P31FUJ	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.8228179328618201	[142]	[94]	-6	hSpCas9	negative selection	10155696
8147450	8147473	19	-	28162770	P31FUJ	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	1.167128402474257	[35]	[94]	9	hSpCas9	negative selection	10155697
8147340	8147363	19	-	28162770	P31FUJ	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.4248055981385433	[283]	[447]	5	hSpCas9	negative selection	10155698
8147313	8147336	19	-	28162770	P31FUJ	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.3137192200027028	[392]	[573]	3	hSpCas9	negative selection	10155699
8146138	8146161	19	-	28162770	P31FUJ	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.929657585206432	[401]	[247]	-6	hSpCas9	negative selection	10155700
8142075	8142098	19	-	28162770	P31FUJ	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.4512076655575865	[393]	[632]	5	hSpCas9	negative selection	10155701
8138255	8138278	19	+	28162770	P31FUJ	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	10155702
8141961	8141984	19	+	28162770	TF1	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10325059
8136434	8136457	19	+	28162770	TF1	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10325060
8095979	8096002	19	+	28162770	TF1	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10325061
8085540	8085563	19	-	28162770	TF1	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10325062
8147450	8147473	19	-	28162770	TF1	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10325063
8147340	8147363	19	-	28162770	TF1	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	NaN	[NaN]	[298]	1	hSpCas9	negative selection	10325064
8147313	8147336	19	-	28162770	TF1	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	NaN	[NaN]	[501]	1	hSpCas9	negative selection	10325065
8146138	8146161	19	-	28162770	TF1	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	NaN	[NaN]	[353]	1	hSpCas9	negative selection	10325066
8142075	8142098	19	-	28162770	TF1	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	NaN	[NaN]	[326]	1	hSpCas9	negative selection	10325067
8138255	8138278	19	+	28162770	TF1	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10325068
8141961	8141984	19	+	28162770	SKM1	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.14019626926561	[57]	[112]	1	hSpCas9	negative selection	10494425
8136434	8136457	19	+	28162770	SKM1	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.3580545982622154	[28]	[39]	-3	hSpCas9	negative selection	10494426
8095979	8096002	19	+	28162770	SKM1	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.03909981968894022	[67]	[116]	0	hSpCas9	negative selection	10494427
8085540	8085563	19	-	28162770	SKM1	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	0.21116516591319365	[42]	[87]	2	hSpCas9	negative selection	10494428
8147450	8147473	19	-	28162770	SKM1	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.09953567355091453	[19]	[32]	-1	hSpCas9	negative selection	10494429
8147340	8147363	19	-	28162770	SKM1	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.3756000278338265	[90]	[123]	-3	hSpCas9	negative selection	10494430
8147313	8147336	19	-	28162770	SKM1	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.1505175655558877	[105]	[207]	1	hSpCas9	negative selection	10494431
8146138	8146161	19	-	28162770	SKM1	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.5463672554085781	[94]	[114]	-4	hSpCas9	negative selection	10494432
8142075	8142098	19	-	28162770	SKM1	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.16872048838998388	[77]	[154]	1	hSpCas9	negative selection	10494433
8138255	8138278	19	+	28162770	SKM1	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10494434
8141961	8141984	19	+	28162770	SKM1	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.14019626926561	[57]	[112]	1	hSpCas9	negative selection	10663791
8136434	8136457	19	+	28162770	SKM1	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.3580545982622154	[28]	[39]	-3	hSpCas9	negative selection	10663792
8095979	8096002	19	+	28162770	SKM1	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.03909981968894022	[67]	[116]	0	hSpCas9	negative selection	10663793
8085540	8085563	19	-	28162770	SKM1	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	0.21116516591319365	[42]	[87]	2	hSpCas9	negative selection	10663794
8147450	8147473	19	-	28162770	SKM1	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.09953567355091453	[19]	[32]	-1	hSpCas9	negative selection	10663795
8147340	8147363	19	-	28162770	SKM1	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.3756000278338265	[90]	[123]	-3	hSpCas9	negative selection	10663796
8147313	8147336	19	-	28162770	SKM1	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.1505175655558877	[105]	[207]	1	hSpCas9	negative selection	10663797
8146138	8146161	19	-	28162770	SKM1	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.5463672554085781	[94]	[114]	-4	hSpCas9	negative selection	10663798
8142075	8142098	19	-	28162770	SKM1	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.16872048838998388	[77]	[154]	1	hSpCas9	negative selection	10663799
8138255	8138278	19	+	28162770	SKM1	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10663800
8141961	8141984	19	+	28162770	PL21	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	-0.6955237256959443	[159]	[42]	-5	hSpCas9	negative selection	10833157
8136434	8136457	19	+	28162770	PL21	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	0.64944701585291	[103]	[70]	5	hSpCas9	negative selection	10833158
8095979	8096002	19	+	28162770	PL21	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	1.0666159416519305	[180]	[164]	8	hSpCas9	negative selection	10833159
8085540	8085563	19	-	28162770	PL21	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.30887403299853766	[110]	[38]	-2	hSpCas9	negative selection	10833160
8147450	8147473	19	-	28162770	PL21	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-1.062894791344474	[47]	[9]	-6	hSpCas9	negative selection	10833161
8147340	8147363	19	-	28162770	PL21	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.13648097726700226	[277]	[132]	1	hSpCas9	negative selection	10833162
8147313	8147336	19	-	28162770	PL21	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	-0.9353753561671609	[289]	[65]	-6	hSpCas9	negative selection	10833163
8146138	8146161	19	-	28162770	PL21	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	0.4402736182130352	[253]	[149]	4	hSpCas9	negative selection	10833164
8142075	8142098	19	-	28162770	PL21	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.30705481840583215	[220]	[118]	2	hSpCas9	negative selection	10833165
8138255	8138278	19	+	28162770	PL21	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10833166
8141961	8141984	19	+	28162770	P31FUJ	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.06348400721580005	[192]	[236]	0	hSpCas9	negative selection	11002523
8136434	8136457	19	+	28162770	P31FUJ	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.217120582182109	[182]	[184]	-2	hSpCas9	negative selection	11002524
8095979	8096002	19	+	28162770	P31FUJ	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	0.24896140866527844	[168]	[235]	2	hSpCas9	negative selection	11002525
8085540	8085563	19	-	28162770	P31FUJ	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.8228179328618201	[142]	[94]	-6	hSpCas9	negative selection	11002526
8147450	8147473	19	-	28162770	P31FUJ	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	1.167128402474257	[35]	[94]	9	hSpCas9	negative selection	11002527
8147340	8147363	19	-	28162770	P31FUJ	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.4248055981385433	[283]	[447]	5	hSpCas9	negative selection	11002528
8147313	8147336	19	-	28162770	P31FUJ	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.3137192200027028	[392]	[573]	3	hSpCas9	negative selection	11002529
8146138	8146161	19	-	28162770	P31FUJ	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.929657585206432	[401]	[247]	-6	hSpCas9	negative selection	11002530
8142075	8142098	19	-	28162770	P31FUJ	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.4512076655575865	[393]	[632]	5	hSpCas9	negative selection	11002531
8138255	8138278	19	+	28162770	P31FUJ	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	11002532
8141961	8141984	19	+	28162770	OCIAML5	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	-0.7864782292364201	[128]	[134]	-5	hSpCas9	negative selection	11171889
8136434	8136457	19	+	28162770	OCIAML5	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.9093997459299485	[76]	[73]	-5	hSpCas9	negative selection	11171890
8095979	8096002	19	+	28162770	OCIAML5	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.8520665708639972	[71]	[71]	-5	hSpCas9	negative selection	11171891
8085540	8085563	19	-	28162770	OCIAML5	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	1.8260053342486409	[29]	[191]	9	hSpCas9	negative selection	11171892
8147450	8147473	19	-	28162770	OCIAML5	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	0.9874687569427572	[18]	[67]	8	hSpCas9	negative selection	11171893
8147340	8147363	19	-	28162770	OCIAML5	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.10428554423317221	[150]	[292]	0	hSpCas9	negative selection	11171894
8147313	8147336	19	-	28162770	OCIAML5	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	-0.5901457853409117	[215]	[258]	-4	hSpCas9	negative selection	11171895
8146138	8146161	19	-	28162770	OCIAML5	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.6316765024386968	[205]	[239]	-4	hSpCas9	negative selection	11171896
8142075	8142098	19	-	28162770	OCIAML5	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	-0.5727828133851283	[205]	[249]	-4	hSpCas9	negative selection	11171897
8138255	8138278	19	+	28162770	OCIAML5	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11171898
8141961	8141984	19	+	28162770	EOL1	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	-1.5389766017006457	[352]	[63]	-7	hSpCas9	negative selection	11341255
8136434	8136457	19	+	28162770	EOL1	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	1.1302964367871107	[136]	[157]	8	hSpCas9	negative selection	11341256
8095979	8096002	19	+	28162770	EOL1	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.2882586009367153	[349]	[150]	-2	hSpCas9	negative selection	11341257
8085540	8085563	19	-	28162770	EOL1	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	0.44836161676671005	[248]	[178]	4	hSpCas9	negative selection	11341258
8147450	8147473	19	-	28162770	EOL1	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	1.6439193057220025	[98]	[162]	9	hSpCas9	negative selection	11341259
8147340	8147363	19	-	28162770	EOL1	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.5214383160018112	[533]	[195]	-4	hSpCas9	negative selection	11341260
8147313	8147336	19	-	28162770	EOL1	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.4990178984740485	[367]	[273]	4	hSpCas9	negative selection	11341261
8146138	8146161	19	-	28162770	EOL1	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.7910441718031049	[334]	[101]	-5	hSpCas9	negative selection	11341262
8142075	8142098	19	-	28162770	EOL1	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.7465494695925402	[335]	[296]	6	hSpCas9	negative selection	11341263
8138255	8138278	19	+	28162770	EOL1	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	0.924547771570535	[0]	[0]	7	hSpCas9	negative selection	11341264
8141961	8141984	19	+	28162770	MOLM13	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	-0.1624650219905917	[225]	[145]	-1	hSpCas9	negative selection	11510621
8136434	8136457	19	+	28162770	MOLM13	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	0.7544121403007424	[131]	[160]	6	hSpCas9	negative selection	11510622
8095979	8096002	19	+	28162770	MOLM13	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.678952006784692	[309]	[139]	-4	hSpCas9	negative selection	11510623
8085540	8085563	19	-	28162770	MOLM13	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.1601418410684633	[169]	[109]	-1	hSpCas9	negative selection	11510624
8147450	8147473	19	-	28162770	MOLM13	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	1.523171817045768	[63]	[132]	9	hSpCas9	negative selection	11510625
8147340	8147363	19	-	28162770	MOLM13	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.8409851177501142	[348]	[451]	6	hSpCas9	negative selection	11510626
8147313	8147336	19	-	28162770	MOLM13	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	-1.1607944966058952	[401]	[129]	-6	hSpCas9	negative selection	11510627
8146138	8146161	19	-	28162770	MOLM13	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-1.1360312768804617	[382]	[125]	-5	hSpCas9	negative selection	11510628
8142075	8142098	19	-	28162770	MOLM13	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	-0.35046453946228234	[394]	[223]	-2	hSpCas9	negative selection	11510629
8138255	8138278	19	+	28162770	MOLM13	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	0.4678893815445777	[0]	[0]	3	hSpCas9	negative selection	11510630
8141961	8141984	19	+	28162770	HEL	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	-0.8166927866369403	[197]	[71]	-5	hSpCas9	negative selection	11679987
8136434	8136457	19	+	28162770	HEL	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-1.002596286700281	[121]	[38]	-6	hSpCas9	negative selection	11679988
8095979	8096002	19	+	28162770	HEL	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.46630392729493314	[260]	[120]	-3	hSpCas9	negative selection	11679989
8085540	8085563	19	-	28162770	HEL	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-1.6333855732738805	[154]	[31]	-7	hSpCas9	negative selection	11679990
8147450	8147473	19	-	28162770	HEL	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	0.2468101556692175	[49]	[37]	2	hSpCas9	negative selection	11679991
8147340	8147363	19	-	28162770	HEL	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.5405683813627028	[351]	[154]	-4	hSpCas9	negative selection	11679992
8147313	8147336	19	-	28162770	HEL	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	-1.0918000247713093	[395]	[118]	-6	hSpCas9	negative selection	11679993
8146138	8146161	19	-	28162770	HEL	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.6913298257592173	[357]	[141]	-4	hSpCas9	negative selection	11679994
8142075	8142098	19	-	28162770	HEL	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	-0.031133084582995074	[342]	[214]	0	hSpCas9	negative selection	11679995
8138255	8138278	19	+	28162770	HEL	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	0.6427388320003571	[0]	[0]	5	hSpCas9	negative selection	11679996
8141961	8141984	19	+	28162770	MV411	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.08290177877088462	[166]	[148]	0	hSpCas9	negative selection	11849353
8136434	8136457	19	+	28162770	MV411	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-1.5025841962088773	[110]	[32]	-7	hSpCas9	negative selection	11849354
8095979	8096002	19	+	28162770	MV411	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.23616423497914005	[157]	[112]	-2	hSpCas9	negative selection	11849355
8085540	8085563	19	-	28162770	MV411	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-1.0358692500772797	[128]	[52]	-6	hSpCas9	negative selection	11849356
8147450	8147473	19	-	28162770	MV411	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.9838879953236808	[53]	[22]	-6	hSpCas9	negative selection	11849357
8147340	8147363	19	-	28162770	MV411	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.9815350189773857	[292]	[124]	-6	hSpCas9	negative selection	11849358
8147313	8147336	19	-	28162770	MV411	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	-0.1227861011453682	[242]	[187]	-1	hSpCas9	negative selection	11849359
8146138	8146161	19	-	28162770	MV411	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.8825210433418922	[266]	[121]	-6	hSpCas9	negative selection	11849360
8142075	8142098	19	-	28162770	MV411	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	-0.027569496717094633	[241]	[199]	0	hSpCas9	negative selection	11849361
8138255	8138278	19	+	28162770	MV411	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11849362
8141961	8141984	19	+	28162770	MONOMAC1	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	1.1069055023544463	[112]	[278]	8	hSpCas9	negative selection	12018719
8136434	8136457	19	+	28162770	MONOMAC1	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.5626863193762339	[66]	[51]	-5	hSpCas9	negative selection	12018720
8095979	8096002	19	+	28162770	MONOMAC1	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	0.2263641251539169	[128]	[172]	2	hSpCas9	negative selection	12018721
8085540	8085563	19	-	28162770	MONOMAC1	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.45419468655667833	[97]	[81]	-4	hSpCas9	negative selection	12018722
8147450	8147473	19	-	28162770	MONOMAC1	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.7819993477807099	[50]	[33]	-6	hSpCas9	negative selection	12018723
8147340	8147363	19	-	28162770	MONOMAC1	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.3865146459232665	[194]	[170]	-3	hSpCas9	negative selection	12018724
8147313	8147336	19	-	28162770	MONOMAC1	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.3664459262511509	[202]	[299]	3	hSpCas9	negative selection	12018725
8146138	8146161	19	-	28162770	MONOMAC1	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.7211171056336874	[173]	[120]	-5	hSpCas9	negative selection	12018726
8142075	8142098	19	-	28162770	MONOMAC1	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.16783785748119523	[138]	[178]	1	hSpCas9	negative selection	12018727
8138255	8138278	19	+	28162770	MONOMAC1	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	12018728
8141961	8141984	19	+	28162770	OCIAML2	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	-0.5611421181476036	[36]	[138]	-4	hSpCas9	negative selection	12188085
8136434	8136457	19	+	28162770	OCIAML2	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	0.9324943524931821	[18]	[200]	8	hSpCas9	negative selection	12188086
8095979	8096002	19	+	28162770	OCIAML2	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	0.36587144247495945	[34]	[249]	3	hSpCas9	negative selection	12188087
8085540	8085563	19	-	28162770	OCIAML2	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.5112718097395073	[26]	[104]	-4	hSpCas9	negative selection	12188088
8147450	8147473	19	-	28162770	OCIAML2	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	-0.470629825242161	[9]	[39]	-4	hSpCas9	negative selection	12188089
8147340	8147363	19	-	28162770	OCIAML2	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	0.5388305040069051	[37]	[305]	5	hSpCas9	negative selection	12188090
8147313	8147336	19	-	28162770	OCIAML2	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.5954593652156113	[47]	[401]	6	hSpCas9	negative selection	12188091
8146138	8146161	19	-	28162770	OCIAML2	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.9955449422933784	[49]	[138]	-6	hSpCas9	negative selection	12188092
8142075	8142098	19	-	28162770	OCIAML2	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.1799210171065716	[42]	[269]	1	hSpCas9	negative selection	12188093
8138255	8138278	19	+	28162770	OCIAML2	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12188094
8141961	8141984	19	+	28162770	OCIAML3	viability	TATTGGGGATGAAGCCGCGGCGG	FBN3	ENSG00000142449	0.6111067895804495	[35]	[165]	5	hSpCas9	negative selection	12357451
8136434	8136457	19	+	28162770	OCIAML3	viability	GCAGCGGTAGCTGGAAGGCGTGG	FBN3	ENSG00000142449	-0.4240826388818507	[27]	[62]	-3	hSpCas9	negative selection	12357452
8095979	8096002	19	+	28162770	OCIAML3	viability	TGTGTGTCACCACAAAGCCAGGG	FBN3	ENSG00000142449	-0.5496135209657098	[47]	[98]	-4	hSpCas9	negative selection	12357453
8085540	8085563	19	-	28162770	OCIAML3	viability	GCAGGGGCCCTGCTTTGCCGAGG	FBN3	ENSG00000142449	-0.1254546317183176	[42]	[118]	-1	hSpCas9	negative selection	12357454
8147450	8147473	19	-	28162770	OCIAML3	viability	GGAGGGTCTGTATTTGGCAAGGG	FBN3	ENSG00000142449	0.7845039829295664	[9]	[51]	7	hSpCas9	negative selection	12357455
8147340	8147363	19	-	28162770	OCIAML3	viability	CAGGTCCTGGACGTGTGCGGAGG	FBN3	ENSG00000142449	-0.27207954543680085	[85]	[214]	-2	hSpCas9	negative selection	12357456
8147313	8147336	19	-	28162770	OCIAML3	viability	GCAGCCCAGGCATCTTGCAGGGG	FBN3	ENSG00000142449	0.1868750703722497	[109]	[377]	1	hSpCas9	negative selection	12357457
8146138	8146161	19	-	28162770	OCIAML3	viability	GGGACGCTGGCTCCCAGCTGCGG	FBN3	ENSG00000142449	-0.813320668728639	[77]	[133]	-6	hSpCas9	negative selection	12357458
8142075	8142098	19	-	28162770	OCIAML3	viability	GGGGTGCCAGCATCAGCTGACGG	FBN3	ENSG00000142449	0.20805298206392797	[77]	[271]	2	hSpCas9	negative selection	12357459
8138255	8138278	19	+	28162770	OCIAML3	viability	GGCCAGGGAAGAGGCCAGGGTGG	FBN3	ENSG00000142449	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12357460