Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23403
• Symbol:FBXO46
• Description:F-box protein 46

DataSource: http://genomecrispr.dkfz.de/#!/results/FBXO46

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45712808	45712831	19	-	26472758	Jiyoye	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	-0.5133901509997214	[52]	[27]	-4	hSpCas9	negative selection	56882
45712270	45712293	19	+	26472758	Jiyoye	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-2.6183597106012644	[170]	[20]	-9	hSpCas9	negative selection	56883
45713434	45713457	19	+	26472758	Jiyoye	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	1.8943379558767361	[177]	[498]	8	hSpCas9	negative selection	56884
45713263	45713286	19	+	26472758	Jiyoye	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.4503803534739211	[211]	[116]	-3	hSpCas9	negative selection	56885
45713094	45713117	19	-	26472758	Jiyoye	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.24961986397634928	[174]	[110]	-2	hSpCas9	negative selection	56886
45712834	45712857	19	-	26472758	Jiyoye	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	2.023846741954368	[14]	[45]	8	hSpCas9	negative selection	56887
45712743	45712766	19	-	26472758	Jiyoye	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-0.20341292689077714	[141]	[92]	-1	hSpCas9	negative selection	56888
45712666	45712689	19	-	26472758	Jiyoye	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.5257104226355894	[293]	[153]	-4	hSpCas9	negative selection	56889
45712517	45712540	19	+	26472758	Jiyoye	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	0.03305107549308273	[196]	[151]	0	hSpCas9	negative selection	56890
45712328	45712351	19	-	26472758	Jiyoye	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-1.8939941532146913	[137]	[27]	-8	hSpCas9	negative selection	56891
45712808	45712831	19	-	26472758	KBM7	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.8870519621959353	[268,115]	[285,49]	8	hSpCas9	negative selection	248000
45712270	45712293	19	+	26472758	KBM7	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-1.2974879304466047	[440,241]	[59,66]	-7	hSpCas9	negative selection	248001
45713434	45713457	19	+	26472758	KBM7	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.6114460535601489	[804,308]	[433,338]	6	hSpCas9	negative selection	248002
45713263	45713286	19	+	26472758	KBM7	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.23467948686164045	[659,634]	[372,157]	-2	hSpCas9	negative selection	248003
45713094	45713117	19	-	26472758	KBM7	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.7152525433027908	[620,401]	[162,126]	-5	hSpCas9	negative selection	248004
45712834	45712857	19	-	26472758	KBM7	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.164868437235693	[193,93]	[90,57]	1	hSpCas9	negative selection	248005
45712743	45712766	19	-	26472758	KBM7	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-0.4393583534352153	[389,439]	[107,178]	-4	hSpCas9	negative selection	248006
45712666	45712689	19	-	26472758	KBM7	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	0.6286987167975095	[907,1133]	[1022,513]	7	hSpCas9	negative selection	248007
45712517	45712540	19	+	26472758	KBM7	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.07193207371580523	[694,770]	[345,317]	0	hSpCas9	negative selection	248008
45712328	45712351	19	-	26472758	KBM7	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	0.7415253568741735	[334,476]	[374,282]	7	hSpCas9	negative selection	248009
45712808	45712831	19	-	26472758	Raji	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.8443491295398057	[107]	[44]	7	hSpCas9	negative selection	439118
45712270	45712293	19	+	26472758	Raji	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-1.1815941377124761	[302]	[30]	-7	hSpCas9	negative selection	439119
45713434	45713457	19	+	26472758	Raji	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.8680925894637833	[228]	[96]	7	hSpCas9	negative selection	439120
45713263	45713286	19	+	26472758	Raji	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.7460678012734586	[317]	[43]	-5	hSpCas9	negative selection	439121
45713094	45713117	19	-	26472758	Raji	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.30765396390524435	[207]	[38]	-3	hSpCas9	negative selection	439122
45712834	45712857	19	-	26472758	Raji	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	1.5033122117047386	[37]	[24]	9	hSpCas9	negative selection	439123
45712743	45712766	19	-	26472758	Raji	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-0.3555884409689464	[203]	[36]	-3	hSpCas9	negative selection	439124
45712666	45712689	19	-	26472758	Raji	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.19705713278492176	[409]	[82]	-2	hSpCas9	negative selection	439125
45712517	45712540	19	+	26472758	Raji	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.8406530430049501	[408]	[52]	-6	hSpCas9	negative selection	439126
45712328	45712351	19	-	26472758	Raji	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	0.08299937674664043	[178]	[43]	0	hSpCas9	negative selection	439127
45712808	45712831	19	-	26472758	K562	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.9099996885958875	[115]	[183]	7	hSpCas9	negative selection	630236
45712270	45712293	19	+	26472758	K562	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-1.0045485660317968	[346]	[145]	-5	hSpCas9	negative selection	630237
45713434	45713457	19	+	26472758	K562	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	1.432786334062224	[379]	[865]	9	hSpCas9	negative selection	630238
45713263	45713286	19	+	26472758	K562	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-1.494495138289281	[493]	[147]	-6	hSpCas9	negative selection	630239
45713094	45713117	19	-	26472758	K562	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	0.36499239098814845	[412]	[448]	3	hSpCas9	negative selection	630240
45712834	45712857	19	-	26472758	K562	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.5850062777854096	[168]	[213]	5	hSpCas9	negative selection	630241
45712743	45712766	19	-	26472758	K562	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	0.4235622591381381	[415]	[470]	3	hSpCas9	negative selection	630242
45712666	45712689	19	-	26472758	K562	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.13513618480297085	[829]	[637]	-1	hSpCas9	negative selection	630243
45712517	45712540	19	+	26472758	K562	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-1.0356891915262882	[628]	[258]	-5	hSpCas9	negative selection	630244
45712328	45712351	19	-	26472758	K562	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	0.856757667318908	[434]	[664]	7	hSpCas9	negative selection	630245
45712142	45712165	19	+	26627737	DLD1	viability	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	1.3125570826201147	[63]	[5,24,107]	9	hSpCas9	negative selection	805520
45712146	45712169	19	+	26627737	DLD1	viability	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.24195535794437728	[607]	[184,253,234]	2	hSpCas9	negative selection	805521
45712247	45712270	19	-	26627737	DLD1	viability	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.09274402964060291	[266]	[18,43,157]	-1	hSpCas9	negative selection	805522
45712688	45712711	19	-	26627737	DLD1	viability	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.7034492597346605	[293]	[37,97,37]	-6	hSpCas9	negative selection	805523
45712862	45712885	19	-	26627737	DLD1	viability	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.5985719008033168	[1464]	[966,595,536]	6	hSpCas9	negative selection	805524
45712888	45712911	19	+	26627737	DLD1	viability	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.047756755340536805	[257]	[42,55,140]	0	hSpCas9	negative selection	805525
45712142	45712165	19	+	26627737	GBM cells	viability after 5 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.6489356218773383	[21]	[15,20]	8	hSpCas9	negative selection	887835
45712146	45712169	19	+	26627737	GBM cells	viability after 5 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.24752969321746388	[258]	[98,134]	-4	hSpCas9	negative selection	887836
45712247	45712270	19	-	26627737	GBM cells	viability after 5 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.015356251088430417	[97]	[53,49]	0	hSpCas9	negative selection	887837
45712688	45712711	19	-	26627737	GBM cells	viability after 5 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.09130510432172922	[146]	[50,96]	-1	hSpCas9	negative selection	887838
45712862	45712885	19	-	26627737	GBM cells	viability after 5 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.5545017658469443	[484]	[389,373]	7	hSpCas9	negative selection	887839
45712888	45712911	19	+	26627737	GBM cells	viability after 5 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.3929027155593514	[119]	[82,85]	6	hSpCas9	negative selection	887840
45712142	45712165	19	+	26627737	GBM cells	viability after 13 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.9197014606666856	[21]	[10,31]	9	hSpCas9	negative selection	970150
45712146	45712169	19	+	26627737	GBM cells	viability after 13 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.12191632789166917	[258]	[132,125]	-1	hSpCas9	negative selection	970151
45712247	45712270	19	-	26627737	GBM cells	viability after 13 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.009454987291244166	[97]	[63,44]	0	hSpCas9	negative selection	970152
45712688	45712711	19	-	26627737	GBM cells	viability after 13 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.4240000041472325	[146]	[59,58]	-5	hSpCas9	negative selection	970153
45712862	45712885	19	-	26627737	GBM cells	viability after 13 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.7917790143484736	[484]	[561,368]	8	hSpCas9	negative selection	970154
45712888	45712911	19	+	26627737	GBM cells	viability after 13 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.4353672416223916	[119]	[108,70]	5	hSpCas9	negative selection	970155
45712142	45712165	19	+	26627737	GBM cells	viability after 21 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	1.2102990996297223	[21]	[23,30]	9	hSpCas9	negative selection	1052465
45712146	45712169	19	+	26627737	GBM cells	viability after 21 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.13519807195841438	[258]	[136,119]	-1	hSpCas9	negative selection	1052466
45712247	45712270	19	-	26627737	GBM cells	viability after 21 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.22874066645873903	[97]	[64,59]	2	hSpCas9	negative selection	1052467
45712688	45712711	19	-	26627737	GBM cells	viability after 21 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.9317088919375975	[146]	[44,38]	-7	hSpCas9	negative selection	1052468
45712862	45712885	19	-	26627737	GBM cells	viability after 21 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.4617764366605509	[484]	[388,338]	5	hSpCas9	negative selection	1052469
45712888	45712911	19	+	26627737	GBM cells	viability after 21 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.2587449228693881	[119]	[77,77]	2	hSpCas9	negative selection	1052470
45712142	45712165	19	+	26627737	RPE1	viability after 9 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.9003979809526679	[50]	[24,35]	6	hSpCas9	negative selection	1134780
45712146	45712169	19	+	26627737	RPE1	viability after 9 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.26137630900777137	[895]	[323,351]	1	hSpCas9	negative selection	1134781
45712247	45712270	19	-	26627737	RPE1	viability after 9 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.5202127643495954	[428]	[73,118]	-4	hSpCas9	negative selection	1134782
45712688	45712711	19	-	26627737	RPE1	viability after 9 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.5769488857164936	[368]	[146,204]	4	hSpCas9	negative selection	1134783
45712862	45712885	19	-	26627737	RPE1	viability after 9 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.30517271979102945	[1947]	[825,659]	2	hSpCas9	negative selection	1134784
45712888	45712911	19	+	26627737	RPE1	viability after 9 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.30605216555493375	[286]	[97,39]	-2	hSpCas9	negative selection	1134785
45712142	45712165	19	+	26627737	RPE1	viability after 12 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.4952824890388605	[50]	[29,7]	3	hSpCas9	negative selection	1217095
45712146	45712169	19	+	26627737	RPE1	viability after 12 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.2809788410693195	[895]	[257,328]	2	hSpCas9	negative selection	1217096
45712247	45712270	19	-	26627737	RPE1	viability after 12 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.36559764963270436	[428]	[104,72]	-2	hSpCas9	negative selection	1217097
45712688	45712711	19	-	26627737	RPE1	viability after 12 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.5872495332637879	[368]	[112,186]	4	hSpCas9	negative selection	1217098
45712862	45712885	19	-	26627737	RPE1	viability after 12 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.5204535763827323	[1947]	[893,598]	3	hSpCas9	negative selection	1217099
45712888	45712911	19	+	26627737	RPE1	viability after 12 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.10027207598208321	[286]	[104,58]	0	hSpCas9	negative selection	1217100
45712142	45712165	19	+	26627737	RPE1	viability after 15 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	1.1921342294608426	[50]	[34,30]	6	hSpCas9	negative selection	1299410
45712146	45712169	19	+	26627737	RPE1	viability after 15 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.08929419436502098	[895]	[139,332]	0	hSpCas9	negative selection	1299411
45712247	45712270	19	-	26627737	RPE1	viability after 15 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.3776224938997418	[428]	[182,6]	-2	hSpCas9	negative selection	1299412
45712688	45712711	19	-	26627737	RPE1	viability after 15 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.4410277047996298	[368]	[101,179]	3	hSpCas9	negative selection	1299413
45712862	45712885	19	-	26627737	RPE1	viability after 15 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.49264659908740516	[1947]	[1093,467]	3	hSpCas9	negative selection	1299414
45712888	45712911	19	+	26627737	RPE1	viability after 15 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-1.3268287349846797	[286]	[39,24]	-7	hSpCas9	negative selection	1299415
45712142	45712165	19	+	26627737	RPE1	viability after 18 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	1.444875969241676	[50]	[21,53]	7	hSpCas9	negative selection	1381725
45712146	45712169	19	+	26627737	RPE1	viability after 18 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.2896631269986038	[895]	[282,308]	1	hSpCas9	negative selection	1381726
45712247	45712270	19	-	26627737	RPE1	viability after 18 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.3617179651909822	[428]	[92,86]	-2	hSpCas9	negative selection	1381727
45712688	45712711	19	-	26627737	RPE1	viability after 18 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	1.0214854855954483	[368]	[191,212]	6	hSpCas9	negative selection	1381728
45712862	45712885	19	-	26627737	RPE1	viability after 18 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.5543030508163029	[1947]	[916,616]	3	hSpCas9	negative selection	1381729
45712888	45712911	19	+	26627737	RPE1	viability after 18 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.2572142073553332	[286]	[79,105]	1	hSpCas9	negative selection	1381730
45712142	45712165	19	+	26627737	HeLa	viability after 8 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	2.7111916216653182	[13]	[66,23,34]	9	hSpCas9	negative selection	1464040
45712146	45712169	19	+	26627737	HeLa	viability after 8 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	1.4669927990695701	[242]	[387,217,291]	8	hSpCas9	negative selection	1464041
45712247	45712270	19	-	26627737	HeLa	viability after 8 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	1.2192774877936021	[96]	[112,159,29]	8	hSpCas9	negative selection	1464042
45712688	45712711	19	-	26627737	HeLa	viability after 8 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.8162190808027365	[80]	[85,95,12]	6	hSpCas9	negative selection	1464043
45712862	45712885	19	-	26627737	HeLa	viability after 8 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.4791980449270832	[970]	[497,705,545]	4	hSpCas9	negative selection	1464044
45712888	45712911	19	+	26627737	HeLa	viability after 8 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.35534283523297694	[274]	[246,56,15]	-3	hSpCas9	negative selection	1464045
45712142	45712165	19	+	26627737	HeLa	viability after 12 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	1.4533524417948631	[13]	[19,21,4]	8	hSpCas9	negative selection	1546355
45712146	45712169	19	+	26627737	HeLa	viability after 12 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	1.7164316248320541	[242]	[671,159,185]	9	hSpCas9	negative selection	1546356
45712247	45712270	19	-	26627737	HeLa	viability after 12 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.8010184640283415	[96]	[157,32,24]	6	hSpCas9	negative selection	1546357
45712688	45712711	19	-	26627737	HeLa	viability after 12 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	1.5715107210229708	[80]	[2,152,133]	9	hSpCas9	negative selection	1546358
45712862	45712885	19	-	26627737	HeLa	viability after 12 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.40188231426900245	[970]	[614,586,384]	3	hSpCas9	negative selection	1546359
45712888	45712911	19	+	26627737	HeLa	viability after 12 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.19559544649173222	[274]	[74,156,153]	1	hSpCas9	negative selection	1546360
45712142	45712165	19	+	26627737	HeLa	viability after 15 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.9412259757095476	[13]	[15,2,13]	7	hSpCas9	negative selection	1628670
45712146	45712169	19	+	26627737	HeLa	viability after 15 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	1.3796837424508903	[242]	[205,235,336]	8	hSpCas9	negative selection	1628671
45712247	45712270	19	-	26627737	HeLa	viability after 15 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	1.8831922519175184	[96]	[103,266,59]	9	hSpCas9	negative selection	1628672
45712688	45712711	19	-	26627737	HeLa	viability after 15 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	1.2179441327903973	[80]	[35,16,185]	8	hSpCas9	negative selection	1628673
45712862	45712885	19	-	26627737	HeLa	viability after 15 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.6171546054710568	[970]	[489,584,756]	5	hSpCas9	negative selection	1628674
45712888	45712911	19	+	26627737	HeLa	viability after 15 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.31203201371347355	[274]	[50,69,154]	-3	hSpCas9	negative selection	1628675
45712142	45712165	19	+	26627737	HeLa	viability after 18 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	1.050641079961708	[13]	[11,2,13]	7	hSpCas9	negative selection	1710985
45712146	45712169	19	+	26627737	HeLa	viability after 18 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	1.3775195407590033	[242]	[136,195,336]	8	hSpCas9	negative selection	1710986
45712247	45712270	19	-	26627737	HeLa	viability after 18 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	1.9260962318410526	[96]	[75,223,59]	9	hSpCas9	negative selection	1710987
45712688	45712711	19	-	26627737	HeLa	viability after 18 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	1.2465126250454635	[80]	[27,12,185]	8	hSpCas9	negative selection	1710988
45712862	45712885	19	-	26627737	HeLa	viability after 18 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.611897155830105	[970]	[315,494,756]	5	hSpCas9	negative selection	1710989
45712888	45712911	19	+	26627737	HeLa	viability after 18 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.38792259799035134	[274]	[29,51,154]	-3	hSpCas9	negative selection	1710990
45712142	45712165	19	+	26627737	HCT116	viability after 6 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	2.3929459111532774	[17]	[39,0]	9	hSpCas9	negative selection	1793300
45712146	45712169	19	+	26627737	HCT116	viability after 6 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-1.893931187538571	[508]	[36,12]	-8	hSpCas9	negative selection	1793301
45712247	45712270	19	-	26627737	HCT116	viability after 6 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	2.6169616525336066	[167]	[45,225]	9	hSpCas9	negative selection	1793302
45712688	45712711	19	-	26627737	HCT116	viability after 6 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.4911239770451392	[209]	[27,20]	-3	hSpCas9	negative selection	1793303
45712862	45712885	19	-	26627737	HCT116	viability after 6 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.8146749784229181	[1304]	[472,298]	4	hSpCas9	negative selection	1793304
45712888	45712911	19	+	26627737	HCT116	viability after 6 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.3295820671500874	[673]	[20,194]	1	hSpCas9	negative selection	1793305
45712142	45712165	19	+	26627737	HCT116	viability after 8 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	-2.10476229877713	[20]	[0,0,5]	-9	hSpCas9	negative selection	1875615
45712146	45712169	19	+	26627737	HCT116	viability after 8 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.26104423209600636	[444]	[260,159,193]	-3	hSpCas9	negative selection	1875616
45712247	45712270	19	-	26627737	HCT116	viability after 8 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.07436861967048092	[115]	[84,31,84]	0	hSpCas9	negative selection	1875617
45712688	45712711	19	-	26627737	HCT116	viability after 8 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.09407651584291421	[150]	[99,107,58]	1	hSpCas9	negative selection	1875618
45712862	45712885	19	-	26627737	HCT116	viability after 8 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.5624197496881526	[530]	[295,496,499]	5	hSpCas9	negative selection	1875619
45712888	45712911	19	+	26627737	HCT116	viability after 8 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	1.8566389825629557	[68]	[95,149,165]	9	hSpCas9	negative selection	1875620
45712142	45712165	19	+	26627737	HCT116	viability after 9 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	-0.4819222284032012	[17]	[3,2]	-3	hSpCas9	negative selection	1957930
45712146	45712169	19	+	26627737	HCT116	viability after 9 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.08429527148455887	[508]	[147,140]	0	hSpCas9	negative selection	1957931
45712247	45712270	19	-	26627737	HCT116	viability after 9 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.29237695723435064	[167]	[45,61]	2	hSpCas9	negative selection	1957932
45712688	45712711	19	-	26627737	HCT116	viability after 9 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	1.910857571936556	[209]	[402,58]	9	hSpCas9	negative selection	1957933
45712862	45712885	19	-	26627737	HCT116	viability after 9 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.7459814319525138	[1304]	[632,545]	5	hSpCas9	negative selection	1957934
45712888	45712911	19	+	26627737	HCT116	viability after 9 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.057501906197402225	[673]	[174,196]	0	hSpCas9	negative selection	1957935
45712142	45712165	19	+	26627737	HCT116	viability after 12 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	-1.050180663530024	[20]	[3,0,10]	-8	hSpCas9	negative selection	2040245
45712146	45712169	19	+	26627737	HCT116	viability after 12 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.25080236784931315	[444]	[122,192,279]	-3	hSpCas9	negative selection	2040246
45712247	45712270	19	-	26627737	HCT116	viability after 12 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.5436161979331049	[115]	[17,59,49]	-5	hSpCas9	negative selection	2040247
45712688	45712711	19	-	26627737	HCT116	viability after 12 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.34462897034757656	[150]	[124,134,40]	3	hSpCas9	negative selection	2040248
45712862	45712885	19	-	26627737	HCT116	viability after 12 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.8066375993678975	[530]	[509,430,519]	7	hSpCas9	negative selection	2040249
45712888	45712911	19	+	26627737	HCT116	viability after 12 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.9958025706531601	[68]	[44,140,34]	8	hSpCas9	negative selection	2040250
45712142	45712165	19	+	26627737	HCT116	viability after 15 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	-0.22823708091490325	[20]	[11,0,17]	-2	hSpCas9	negative selection	2122560
45712146	45712169	19	+	26627737	HCT116	viability after 15 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.24652005156863444	[444]	[319,404,187]	2	hSpCas9	negative selection	2122561
45712247	45712270	19	-	26627737	HCT116	viability after 15 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.049591588743746584	[115]	[64,48,78]	0	hSpCas9	negative selection	2122562
45712688	45712711	19	-	26627737	HCT116	viability after 15 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.03903801273796781	[150]	[41,166,52]	0	hSpCas9	negative selection	2122563
45712862	45712885	19	-	26627737	HCT116	viability after 15 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.4224654857721938	[530]	[492,387,355]	4	hSpCas9	negative selection	2122564
45712888	45712911	19	+	26627737	HCT116	viability after 15 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	1.8250003039187508	[68]	[165,174,83]	9	hSpCas9	negative selection	2122565
45712142	45712165	19	+	26627737	HCT116	viability after 18 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.27869475507519326	[20]	[11,11,12]	2	hSpCas9	negative selection	2204875
45712146	45712169	19	+	26627737	HCT116	viability after 18 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.3006489203229842	[444]	[188,466,118]	2	hSpCas9	negative selection	2204876
45712247	45712270	19	-	26627737	HCT116	viability after 18 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.2283024074854325	[115]	[16,94,83]	2	hSpCas9	negative selection	2204877
45712688	45712711	19	-	26627737	HCT116	viability after 18 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.02987791311523469	[150]	[70,58,85]	0	hSpCas9	negative selection	2204878
45712862	45712885	19	-	26627737	HCT116	viability after 18 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.5047970642687513	[530]	[369,299,429]	4	hSpCas9	negative selection	2204879
45712888	45712911	19	+	26627737	HCT116	viability after 18 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	1.078344309507595	[68]	[49,72,88]	8	hSpCas9	negative selection	2204880
45713094	45713117	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.6431601474114056	[2,2]	[2,0]	-7	hSpCas9	positive selection	2988243
45713052	45713075	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAGGCTCCTCCTGACCCAGGG	FBXO46	ENSG00000177051	-0.27774160143369686	[5,4]	[4,2]	-4	hSpCas9	positive selection	2988244
45713097	45713120	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGATAGCTCCAAGGCCAAGCGG	FBXO46	ENSG00000177051	-0.15882086863752154	[2,2]	[3,0]	-2	hSpCas9	positive selection	2988245
45713429	45713452	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCTGTGAGTAGGTGCCAAAGGG	FBXO46	ENSG00000177051	-0.1145308135776705	[2,2]	[4,0]	-2	hSpCas9	positive selection	2988246
45713094	45713117	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.06807404811800072	[2,2]	[1,1]	-1	hSpCas9	positive selection	3056101
45713052	45713075	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAGGCTCCTCCTGACCCAGGG	FBXO46	ENSG00000177051	0.13801712477689748	[5,5]	[3,4]	2	hSpCas9	positive selection	3056102
45713097	45713120	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGATAGCTCCAAGGCCAAGCGG	FBXO46	ENSG00000177051	0.02766182163860631	[2,2]	[1,1]	0	hSpCas9	positive selection	3056103
45713429	45713452	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCTGTGAGTAGGTGCCAAAGGG	FBXO46	ENSG00000177051	-0.205492654981645	[2,2]	[2,0]	-3	hSpCas9	positive selection	3056104
45711772	45711795		-	24336571	A375	resistance to PLX after 7 days	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.2819597502513036	[7,7]	[9,9]	7	hSpCas9	positive selection	3114323
45712916	45712939		+	24336571	A375	resistance to PLX after 7 days	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.15723338841159554	[11,7]	[10,10]	5	hSpCas9	positive selection	3114324
45711772	45711795		-	24336571	A375	resistance to PLX after 14 days	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	-0.3021788114301386	[6,7]	[1,2]	-3	hSpCas9	positive selection	3172116
45712916	45712939		+	24336571	A375	resistance to PLX after 14 days	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.21012714841632163	[10,8]	[5,3]	2	hSpCas9	positive selection	3172117
45711772	45711795		-	24336571	A375	viability after 7 days	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	-0.3062568401825902	[10]	[7,7]	-4	hSpCas9	negative selection	3229909
45712916	45712939		+	24336571	A375	viability after 7 days	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.22533292568159258	[8]	[11,7]	3	hSpCas9	negative selection	3229910
45711772	45711795		-	24336571	A375	viability after 14 days	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	-0.3966777430657579	[10]	[6,7]	-5	hSpCas9	negative selection	3287702
45712916	45712939		+	24336571	A375	viability after 14 days	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.2857928538741252	[8]	[10,8]	3	hSpCas9	negative selection	3287703
45711772	45711795	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.7361440606089636	[247,210]	[0,3]	3	hSpCas9	positive selection	3349747
45711815	45711838	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	1.4530053494778643	[37,73]	[0,0]	6	hSpCas9	positive selection	3349748
45712916	45712939	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.36314249530115483	[110,126]	[0,0]	2	hSpCas9	positive selection	3349749
45712397	45712420	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.4150991305256606	[203,203]	[0,0]	-3	hSpCas9	positive selection	3368959
45711899	45711922	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.08252379143878971	[161,161]	[0,0]	0	hSpCas9	positive selection	3368960
45712241	45712264	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	1.2129320920873818	[65,65]	[0,0]	5	hSpCas9	positive selection	3368961
45713094	45713117	19	-	26780180	HT29	viability (Avana library 4 designs)	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	1.8950303666677	[]	[]	7	hSpCas9	negative selection	3425144
45713052	45713075	19	-	26780180	HT29	viability (Avana library 4 designs)	CCAAGGCTCCTCCTGACCCAGGG	FBXO46	ENSG00000177051	0.810756688917752	[]	[]	3	hSpCas9	negative selection	3425145
45713097	45713120	19	-	26780180	HT29	viability (Avana library 4 designs)	GCGATAGCTCCAAGGCCAAGCGG	FBXO46	ENSG00000177051	0.802465458910159	[]	[]	3	hSpCas9	negative selection	3425146
45713428	45713451	19	+	26780180	HT29	viability (Avana library 4 designs)	TTCTGTGAGTAGGTGCCAAAGGG	FBXO46	ENSG00000177051	0.461288585647579	[]	[]	1	hSpCas9	negative selection	3425147
45713094	45713117	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-5.24129152306355	[]	[]	-5	hSpCas9	negative selection	3507130
45713097	45713120	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGATAGCTCCAAGGCCAAGCGG	FBXO46	ENSG00000177051	5.18306477401431	[]	[]	8	hSpCas9	negative selection	3507131
45713428	45713451	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTGTGAGTAGGTGCCAAAGGG	FBXO46	ENSG00000177051	2.31478805095994	[]	[]	3	hSpCas9	negative selection	3507132
45713052	45713075	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGGCTCCTCCTGACCCAGGG	FBXO46	ENSG00000177051	2.79355043922946	[]	[]	4	hSpCas9	negative selection	3507133
45713263	45713286	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.308722974534788	[]	[]	0	hSpCas9	negative selection	3507134
45713201	45713224	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATCAAGCCCGGGAATACAAAGG	FBXO46	ENSG00000177051	-4.39746927006572	[]	[]	-5	hSpCas9	negative selection	3507135
45713094	45713117	19	-	26780180	A375	viability (Avana lentiGuide)	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	5.3188207163829	[]	[]	5	hSpCas9	negative selection	3615789
45713097	45713120	19	-	26780180	A375	viability (Avana lentiGuide)	GCGATAGCTCCAAGGCCAAGCGG	FBXO46	ENSG00000177051	4.13416998383588	[]	[]	4	hSpCas9	negative selection	3615790
45713428	45713451	19	+	26780180	A375	viability (Avana lentiGuide)	TTCTGTGAGTAGGTGCCAAAGGG	FBXO46	ENSG00000177051	1.53564871752243	[]	[]	1	hSpCas9	negative selection	3615791
45713052	45713075	19	-	26780180	A375	viability (Avana lentiGuide)	CCAAGGCTCCTCCTGACCCAGGG	FBXO46	ENSG00000177051	1.30247734619676	[]	[]	1	hSpCas9	negative selection	3615792
45713263	45713286	19	+	26780180	A375	viability (Avana lentiGuide)	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	8.01039267821728	[]	[]	6	hSpCas9	negative selection	3615793
45713201	45713224	19	-	26780180	A375	viability (Avana lentiGuide)	CATCAAGCCCGGGAATACAAAGG	FBXO46	ENSG00000177051	1.73045674798854	[]	[]	2	hSpCas9	negative selection	3615794
45713094	45713117	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.02492145466691137	[4]	[5,4]	0	hSpCas9	positive selection	3724448
45713097	45713120	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGATAGCTCCAAGGCCAAGCGG	FBXO46	ENSG00000177051	0.13645573527988825	[3]	[4,4]	3	hSpCas9	positive selection	3724449
45713428	45713451	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTGTGAGTAGGTGCCAAAGGG	FBXO46	ENSG00000177051	-0.1133527568997888	[4]	[4,3]	-2	hSpCas9	positive selection	3724450
45713052	45713075	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGGCTCCTCCTGACCCAGGG	FBXO46	ENSG00000177051	0.1962953824312472	[5]	[6,6]	5	hSpCas9	positive selection	3724451
45713263	45713286	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.007154900129508035	[4]	[5,3]	0	hSpCas9	positive selection	3724452
45713201	45713224	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCAAGCCCGGGAATACAAAGG	FBXO46	ENSG00000177051	-0.12443001107968829	[5]	[5,4]	-2	hSpCas9	positive selection	3724453
45713094	45713117	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.5797409702861154	[4]	[0,3]	-6	hSpCas9	positive selection	3833055
45713097	45713120	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGATAGCTCCAAGGCCAAGCGG	FBXO46	ENSG00000177051	-0.2778693891104797	[5]	[4,1]	-4	hSpCas9	positive selection	3833056
45713428	45713451	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTGTGAGTAGGTGCCAAAGGG	FBXO46	ENSG00000177051	-0.05390422673324424	[4]	[2,4]	-1	hSpCas9	positive selection	3833057
45713052	45713075	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGGCTCCTCCTGACCCAGGG	FBXO46	ENSG00000177051	0.20858494200440997	[6]	[6,6]	5	hSpCas9	positive selection	3833058
45713263	45713286	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.23260169918276857	[5]	[3,3]	-3	hSpCas9	positive selection	3833059
45713201	45713224	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCAAGCCCGGGAATACAAAGG	FBXO46	ENSG00000177051	0.2755894784925794	[5]	[5,6]	7	hSpCas9	positive selection	3833060
45711815	45711838	19	+	26780180	A375	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.697007076335907	[]	[]	2	hSpCas9	negative selection	3940324
45711899	45711922	19	+	26780180	A375	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	1.25030459235102	[]	[]	6	hSpCas9	negative selection	3940325
45711772	45711795	19	-	26780180	A375	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	1.55805983845971	[]	[]	8	hSpCas9	negative selection	3940326
45712397	45712420	19	-	26780180	A375	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.546284959557109	[]	[]	1	hSpCas9	negative selection	3940327
45712241	45712264	19	+	26780180	A375	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.772668798562495	[]	[]	3	hSpCas9	negative selection	3940328
45712916	45712939	19	+	26780180	A375	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	1.57292158308036	[]	[]	8	hSpCas9	negative selection	3940329
45711815	45711838	19	+	26780180	HT29	viability (GeCKOv2 library)	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.92110454287834	[]	[]	4	hSpCas9	negative selection	4048290
45711899	45711922	19	+	26780180	HT29	viability (GeCKOv2 library)	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	1.20679703276414	[]	[]	6	hSpCas9	negative selection	4048291
45711772	45711795	19	-	26780180	HT29	viability (GeCKOv2 library)	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	1.99144353571833	[]	[]	9	hSpCas9	negative selection	4048292
45712397	45712420	19	-	26780180	HT29	viability (GeCKOv2 library)	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.194159099300361	[]	[]	0	hSpCas9	negative selection	4048293
45712241	45712264	19	+	26780180	HT29	viability (GeCKOv2 library)	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.17265512151097	[]	[]	0	hSpCas9	negative selection	4048294
45712916	45712939	19	+	26780180	HT29	viability (GeCKOv2 library)	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	1.57757721092856	[]	[]	8	hSpCas9	negative selection	4048295
45711772	45711795	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	-0.35362410344850637	[3]	[1,1]	-7	hSpCas9	positive selection	4137331
45712916	45712939	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.08079019535873777	[3]	[2,2]	-2	hSpCas9	positive selection	4137332
45711772	45711795	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	1.0508787663242483	[3]	[3,3,2,3]	7	hSpCas9	positive selection	4201353
45712916	45712939	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.14321278812525873	[2]	[0,2,0,0]	1	hSpCas9	positive selection	4201354
45711772	45711795	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	-0.1648501202792279	[3]	[2,1]	-3	hSpCas9	positive selection	4270800
45711815	45711838	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.09725578800063833	[2]	[2,0]	-2	hSpCas9	positive selection	4270801
45712916	45712939	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.5644721664009452	[2]	[1,0]	-8	hSpCas9	positive selection	4270802
45712397	45712420	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.04525687056132549	[3]	[3,1]	-1	hSpCas9	positive selection	4335064
45711899	45711922	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	1.0715339940216735	[3]	[2,7]	9	hSpCas9	positive selection	4335065
45712241	45712264	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.023375778617377357	[2]	[2,1]	0	hSpCas9	positive selection	4335066
45712802	45712824	19	-	27760321	OCIAML3	viability	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.6341326036741047	[809,575]	[754,932]	7	hSpCas9	negative selection	4400709
45712834	45712856	19	-	27760321	OCIAML3	viability	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.3239012238789274	[937,983]	[923,973]	4	hSpCas9	negative selection	4400710
45712883	45712905	19	+	27760321	OCIAML3	viability	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.30661421205994915	[320,211]	[196,328]	3	hSpCas9	negative selection	4400711
45713094	45713116	19	-	27760321	OCIAML3	viability	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.29680492158823335	[656,612]	[390,421]	-3	hSpCas9	negative selection	4400712
45713229	45713251	19	-	27760321	OCIAML3	viability	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.3081715740220598	[680,655]	[343,525]	-3	hSpCas9	negative selection	4400713
45712802	45712824	19	-	27760321	OCIAML2	viability	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.5378385483661273	[809,575]	[617,1051]	7	hSpCas9	negative selection	4484172
45712834	45712856	19	-	27760321	OCIAML2	viability	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.04571126197298314	[937,983]	[690,958]	0	hSpCas9	negative selection	4484173
45712883	45712905	19	+	27760321	OCIAML2	viability	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	-0.5198381089360445	[320,211]	[99,211]	-5	hSpCas9	negative selection	4484174
45713094	45713116	19	-	27760321	OCIAML2	viability	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.45806631806887915	[656,612]	[336,422]	-5	hSpCas9	negative selection	4484175
45713229	45713251	19	-	27760321	OCIAML2	viability	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	0.3972815264336532	[680,655]	[684,750]	5	hSpCas9	negative selection	4484176
45712802	45712824	19	-	27760321	MV411	viability	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.0014763010264714493	[809,575]	[378,563]	0	hSpCas9	negative selection	4567635
45712834	45712856	19	-	27760321	MV411	viability	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.5062132468844822	[937,983]	[474,1551]	3	hSpCas9	negative selection	4567636
45712883	45712905	19	+	27760321	MV411	viability	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.5829593347844061	[320,211]	[105,490]	4	hSpCas9	negative selection	4567637
45713094	45713116	19	-	27760321	MV411	viability	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.760182731497163	[656,612]	[147,396]	-5	hSpCas9	negative selection	4567638
45713229	45713251	19	-	27760321	MV411	viability	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.9242825103315435	[680,655]	[68,478]	-6	hSpCas9	negative selection	4567639
45712802	45712824	19	-	27760321	HL60	viability	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	-0.2458104127484363	[809,575]	[500,441]	-3	hSpCas9	negative selection	4651098
45712834	45712856	19	-	27760321	HL60	viability	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.2667134127691614	[937,983]	[653,657]	-3	hSpCas9	negative selection	4651099
45712883	45712905	19	+	27760321	HL60	viability	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.25062138447660487	[320,211]	[238,272]	3	hSpCas9	negative selection	4651100
45713094	45713116	19	-	27760321	HL60	viability	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.19748504426818686	[656,612]	[354,555]	-2	hSpCas9	negative selection	4651101
45713229	45713251	19	-	27760321	HL60	viability	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	0.6035131573338232	[680,655]	[604,1070]	7	hSpCas9	negative selection	4651102
45712802	45712824	19	-	27760321	HT1080	viability	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	1.110150947357431	[575,449]	[423,459]	6	hSpCas9	negative selection	4734561
45712834	45712856	19	-	27760321	HT1080	viability	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.1977753913240572	[983,767]	[278,532]	1	hSpCas9	negative selection	4734562
45712883	45712905	19	+	27760321	HT1080	viability	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	-0.286940368599681	[211,165]	[76,44]	-1	hSpCas9	negative selection	4734563
45713094	45713116	19	-	27760321	HT1080	viability	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-7.158464963482683	[612,478]	[1,0]	-9	hSpCas9	negative selection	4734564
45713229	45713251	19	-	27760321	HT1080	viability	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	0.38790013695823256	[655,511]	[112,513]	2	hSpCas9	negative selection	4734565
45712802	45712824	19	-	27760321	HT29	viability after 7 days	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.5488529319936759	[575,449]	[1048,844,1009]	8	hSpCas9	negative selection	4818024
45712834	45712856	19	-	27760321	HT29	viability after 7 days	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.29523056415727456	[983,767]	[1129,877,778]	-4	hSpCas9	negative selection	4818025
45712883	45712905	19	+	27760321	HT29	viability after 7 days	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.5410674951831433	[211,165]	[304,251,491]	7	hSpCas9	negative selection	4818026
45713094	45713116	19	-	27760321	HT29	viability after 7 days	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.13147009585284863	[612,478]	[542,824,542]	-2	hSpCas9	negative selection	4818027
45713229	45713251	19	-	27760321	HT29	viability after 7 days	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	0.22506962571349043	[655,511]	[941,668,1024]	3	hSpCas9	negative selection	4818028
45712802	45712824	19	-	27760321	HT29	viability after 25 days	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.9774902675022614	[575,449]	[726,1292,1504]	9	hSpCas9	negative selection	4901487
45712834	45712856	19	-	27760321	HT29	viability after 25 days	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.3494102835547628	[983,767]	[618,889,865]	-3	hSpCas9	negative selection	4901488
45712883	45712905	19	+	27760321	HT29	viability after 25 days	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.6223439912087905	[211,165]	[229,325,460]	7	hSpCas9	negative selection	4901489
45713094	45713116	19	-	27760321	HT29	viability after 25 days	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-1.2033457224206205	[612,478]	[257,192,372]	-7	hSpCas9	negative selection	4901490
45713229	45713251	19	-	27760321	HT29	viability after 25 days	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.5067470088211199	[655,511]	[517,498,378]	-5	hSpCas9	negative selection	4901491
45712802	45712824	19	-	27760321	HT29	viability after 22 days	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	1.148859387285296	[575,449]	[1342,1549,1048]	9	hSpCas9	negative selection	4984950
45712834	45712856	19	-	27760321	HT29	viability after 22 days	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.17104669972747	[983,767]	[718,904,1080]	-2	hSpCas9	negative selection	4984951
45712883	45712905	19	+	27760321	HT29	viability after 22 days	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.5550630574995985	[211,165]	[186,234,546]	6	hSpCas9	negative selection	4984952
45713094	45713116	19	-	27760321	HT29	viability after 22 days	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.8757218754303863	[612,478]	[520,293,210]	-6	hSpCas9	negative selection	4984953
45713229	45713251	19	-	27760321	HT29	viability after 22 days	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.36921079701255194	[655,511]	[485,460,622]	-4	hSpCas9	negative selection	4984954
45712802	45712824	19	-	27760321	HT29	viability after 19 days	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.8218187602558831	[575,449]	[615,1154,1285]	8	hSpCas9	negative selection	5068413
45712834	45712856	19	-	27760321	HT29	viability after 19 days	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.3124445116670358	[983,767]	[1175,624,662]	-3	hSpCas9	negative selection	5068414
45712883	45712905	19	+	27760321	HT29	viability after 19 days	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.14592143992734108	[211,165]	[386,295,56]	1	hSpCas9	negative selection	5068415
45713094	45713116	19	-	27760321	HT29	viability after 19 days	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.8771159901110236	[612,478]	[378,334,310]	-6	hSpCas9	negative selection	5068416
45713229	45713251	19	-	27760321	HT29	viability after 19 days	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.2726827435187729	[655,511]	[818,176,684]	-3	hSpCas9	negative selection	5068417
45712802	45712824	19	-	27760321	HT29	viability after 16 days	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.9193638101034647	[575,449]	[854,1036,1343]	9	hSpCas9	negative selection	5151876
45712834	45712856	19	-	27760321	HT29	viability after 16 days	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.3913039740697424	[983,767]	[614,713,900]	-4	hSpCas9	negative selection	5151877
45712883	45712905	19	+	27760321	HT29	viability after 16 days	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.4767800903664669	[211,165]	[566,90,255]	5	hSpCas9	negative selection	5151878
45713094	45713116	19	-	27760321	HT29	viability after 16 days	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.2145985325764862	[612,478]	[584,444,556]	-2	hSpCas9	negative selection	5151879
45713229	45713251	19	-	27760321	HT29	viability after 16 days	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.7042232405602709	[655,511]	[467,490,247]	-6	hSpCas9	negative selection	5151880
45712802	45712824	19	-	27760321	HT29	viability after 13 days	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.8536698792201989	[575,449]	[889,1536,815]	9	hSpCas9	negative selection	5235339
45712834	45712856	19	-	27760321	HT29	viability after 13 days	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.415298793604269	[983,767]	[533,929,818]	-5	hSpCas9	negative selection	5235340
45712883	45712905	19	+	27760321	HT29	viability after 13 days	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	-0.576993896392302	[211,165]	[175,152,113]	-6	hSpCas9	negative selection	5235341
45713094	45713116	19	-	27760321	HT29	viability after 13 days	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.7170471653896672	[612,478]	[357,257,530]	-6	hSpCas9	negative selection	5235342
45713229	45713251	19	-	27760321	HT29	viability after 13 days	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.14394256668367467	[655,511]	[701,554,583]	-2	hSpCas9	negative selection	5235343
45712802	45712824	19	-	27760321	HT29	viability after 10 days	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.7578548281190076	[575,449]	[562,1149,1527]	9	hSpCas9	negative selection	5318802
45712834	45712856	19	-	27760321	HT29	viability after 10 days	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.4281060979548925	[983,767]	[705,808,920]	-5	hSpCas9	negative selection	5318803
45712883	45712905	19	+	27760321	HT29	viability after 10 days	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	0.177255004039236	[211,165]	[252,200,342]	2	hSpCas9	negative selection	5318804
45713094	45713116	19	-	27760321	HT29	viability after 10 days	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.0020438293970593824	[612,478]	[774,592,671]	0	hSpCas9	negative selection	5318805
45713229	45713251	19	-	27760321	HT29	viability after 10 days	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	-0.19328836591049559	[655,511]	[689,732,495]	-3	hSpCas9	negative selection	5318806
45712802	45712824	19	-	27760321	MOLM13	viability	AGCCGTGTAGCCGAGGCCGTGG	FBXO46	ENSG00000177051	0.32906054614578106	[809,575]	[277,662]	2	hSpCas9	negative selection	5402265
45712834	45712856	19	-	27760321	MOLM13	viability	GATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.3064421496118245	[937,983]	[524,368]	-2	hSpCas9	negative selection	5402266
45712883	45712905	19	+	27760321	MOLM13	viability	CGGCGGACACAAAGACTACAGG	FBXO46	ENSG00000177051	-1.8135816830592315	[320,211]	[52,32]	-7	hSpCas9	negative selection	5402267
45713094	45713116	19	-	27760321	MOLM13	viability	TAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-1.7678494706652397	[656,612]	[74,130]	-7	hSpCas9	negative selection	5402268
45713229	45713251	19	-	27760321	MOLM13	viability	TCGAGTCCTCCTGGACACGTGG	FBXO46	ENSG00000177051	0.7719899327727563	[680,655]	[709,589]	5	hSpCas9	negative selection	5402269
45730853	45730876	19	+	27661255	K562	viability	GCCGCGCGCTGCATCTCCCTCGG	FBXO46	ENSG00000177051	0.15373197007222766	[733,572]	[592,574]	5	dCas9-KRAB	negative selection	5479823
45730830	45730853	19	-	27661255	K562	viability	GATGGTGAGAGCCCAGGCGCGGG	FBXO46	ENSG00000177051	-0.12016354363021653	[1414,1548]	[1155,1028]	-4	dCas9-KRAB	negative selection	5479824
45730869	45730892	19	-	27661255	K562	viability	GGGGAAACCCGCGTAGCCGAGGG	FBXO46	ENSG00000177051	-0.9041230005842227	[58,54]	[32,16]	-8	dCas9-KRAB	negative selection	5479825
45730890	45730913	19	-	27661255	K562	viability	GAGGCTGGAGAGGAGCGAGTGGG	FBXO46	ENSG00000177051	-0.05824669435292251	[451,549]	[436,336]	-2	dCas9-KRAB	negative selection	5479826
45711772	45711795	19	-	27260156	BXPC3	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.3595088205455045	[789]	[930,1061,1061,1208]	7	hSpCas9	negative selection	5543260
45711815	45711838	19	+	27260156	BXPC3	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.0734567726254608	[247]	[226,322,153,279]	-2	hSpCas9	negative selection	5543261
45712916	45712939	19	+	27260156	BXPC3	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.12675579426468292	[456]	[427,569,475,628]	3	hSpCas9	negative selection	5543262
45712397	45712420	19	-	27260156	BXPC3	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.12516100155204196	[638]	[463,553,607,871]	-3	hSpCas9	negative selection	5607524
45711899	45711922	19	+	27260156	BXPC3	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.06604675700345414	[540]	[416,505,623,639]	-1	hSpCas9	negative selection	5607525
45712241	45712264	19	+	27260156	BXPC3	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.4446218442574647	[281]	[353,342,497,419]	8	hSpCas9	negative selection	5607526
45711772	45711795	19	-	27260156	A673	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.33826717877755563	[789]	[1230,1125,1194,1250]	7	hSpCas9	negative selection	5664511
45711815	45711838	19	+	27260156	A673	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.2215406901998026	[247]	[453,245,326,377]	5	hSpCas9	negative selection	5664512
45712916	45712939	19	+	27260156	A673	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.05092572181948908	[456]	[691,500,469,629]	1	hSpCas9	negative selection	5664513
45712397	45712420	19	-	27260156	A673	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.09866738214244275	[638]	[786,626,743,716]	-2	hSpCas9	negative selection	5728775
45711899	45711922	19	+	27260156	A673	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.16150604356849504	[540]	[919,439,443,560]	-4	hSpCas9	negative selection	5728776
45712241	45712264	19	+	27260156	A673	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.06789286108597115	[281]	[372,347,320,380]	1	hSpCas9	negative selection	5728777
45711772	45711795	19	-	27260156	A375	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.25133713690523074	[789]	[1016,1119,1207,1051]	3	hSpCas9	negative selection	5785762
45711815	45711838	19	+	27260156	A375	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.759441306725222	[247]	[131,231,184,145]	-7	hSpCas9	negative selection	5785763
45712916	45712939	19	+	27260156	A375	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.009156687586981474	[456]	[492,676,525,476]	0	hSpCas9	negative selection	5785764
45712397	45712420	19	-	27260156	A375	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.15925290047610002	[638]	[606,1033,548,545]	-2	hSpCas9	negative selection	5850026
45711899	45711922	19	+	27260156	A375	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.19451113922193383	[540]	[474,693,580,483]	-3	hSpCas9	negative selection	5850027
45712241	45712264	19	+	27260156	A375	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.29299294087383887	[281]	[390,580,333,338]	4	hSpCas9	negative selection	5850028
45711772	45711795	19	-	27260156	COLO741	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.33416838330250564	[789]	[1655,1205,1004]	7	hSpCas9	negative selection	5907013
45711815	45711838	19	+	27260156	COLO741	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.05111473901485364	[247]	[287,352,338]	1	hSpCas9	negative selection	5907014
45712916	45712939	19	+	27260156	COLO741	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.2624027104922105	[456]	[763,753,594]	5	hSpCas9	negative selection	5907015
45712397	45712420	19	-	27260156	COLO741	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.03246536326531463	[638]	[942,912,668]	0	hSpCas9	negative selection	5971277
45711899	45711922	19	+	27260156	COLO741	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.19168324939717393	[540]	[593,663,558]	-4	hSpCas9	negative selection	5971278
45712241	45712264	19	+	27260156	COLO741	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.032604669541482	[281]	[446,388,281]	0	hSpCas9	negative selection	5971279
45711772	45711795	19	-	27260156	CAL120	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.526761757688826	[789]	[1863,1389,1067]	7	hSpCas9	negative selection	6028264
45711815	45711838	19	+	27260156	CAL120	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.04702927157476344	[247]	[197,298,438]	0	hSpCas9	negative selection	6028265
45712916	45712939	19	+	27260156	CAL120	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.6706161979434616	[456]	[1105,708,929]	8	hSpCas9	negative selection	6028266
45712397	45712420	19	-	27260156	CAL120	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.3267174319153062	[638]	[1253,890,886]	5	hSpCas9	negative selection	6092528
45711899	45711922	19	+	27260156	CAL120	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.09277201020138783	[540]	[730,512,663]	-1	hSpCas9	negative selection	6092529
45712241	45712264	19	+	27260156	CAL120	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.45722941784352733	[281]	[371,428,624]	7	hSpCas9	negative selection	6092530
45711772	45711795	19	-	27260156	CADOES1	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.24705582088514455	[789]	[1057,869,903,646]	4	hSpCas9	negative selection	6149515
45711815	45711838	19	+	27260156	CADOES1	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.02901174391494643	[247]	[245,187,246,222]	0	hSpCas9	negative selection	6149516
45712916	45712939	19	+	27260156	CADOES1	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.07349883108273028	[456]	[494,554,320,416]	1	hSpCas9	negative selection	6149517
45712397	45712420	19	-	27260156	CADOES1	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.27844457285291857	[638]	[596,387,547,423]	-5	hSpCas9	negative selection	6213779
45711899	45711922	19	+	27260156	CADOES1	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.16839489919100334	[540]	[418,466,457,446]	-3	hSpCas9	negative selection	6213780
45712241	45712264	19	+	27260156	CADOES1	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.6280705365601645	[281]	[398,367,507,343]	8	hSpCas9	negative selection	6213781
45711772	45711795	19	-	27260156	EWS502	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.3311159343099773	[789]	[818,1071,1153,1200]	6	hSpCas9	negative selection	6270766
45711815	45711838	19	+	27260156	EWS502	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.3041240399689771	[247]	[270,342,287,404]	5	hSpCas9	negative selection	6270767
45712916	45712939	19	+	27260156	EWS502	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.08997865282318568	[456]	[447,457,619,546]	1	hSpCas9	negative selection	6270768
45712397	45712420	19	-	27260156	EWS502	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.20732790488280772	[638]	[853,542,976,749]	3	hSpCas9	negative selection	6335030
45711899	45711922	19	+	27260156	EWS502	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.14499784555175288	[540]	[478,506,489,605]	-3	hSpCas9	negative selection	6335031
45712241	45712264	19	+	27260156	EWS502	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.31080817590169624	[281]	[337,329,403,417]	5	hSpCas9	negative selection	6335032
45711772	45711795	19	-	27260156	EW8	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.33278823864431517	[789]	[871,770,734,863]	6	hSpCas9	negative selection	6392017
45711815	45711838	19	+	27260156	EW8	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.7544705994928175	[247]	[160,104,117,96]	-8	hSpCas9	negative selection	6392018
45712916	45712939	19	+	27260156	EW8	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.17773631976754803	[456]	[718,378,298,330]	3	hSpCas9	negative selection	6392019
45712397	45712420	19	-	27260156	EW8	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.07538385754461552	[638]	[1067,434,389,371]	1	hSpCas9	negative selection	6456281
45711899	45711922	19	+	27260156	EW8	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.515575092081556	[540]	[321,343,251,318]	-7	hSpCas9	negative selection	6456282
45712241	45712264	19	+	27260156	EW8	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.3868006900156991	[281]	[468,162,211,382]	7	hSpCas9	negative selection	6456283
45711772	45711795	19	-	27260156	CORL105	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.11261354876594443	[789]	[1085,1028,1104,798]	2	hSpCas9	negative selection	6513268
45711815	45711838	19	+	27260156	CORL105	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.11978959196253258	[247]	[251,213,259,525]	2	hSpCas9	negative selection	6513269
45712916	45712939	19	+	27260156	CORL105	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.09745773935538973	[456]	[530,622,584,549]	1	hSpCas9	negative selection	6513270
45712397	45712420	19	-	27260156	CORL105	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.20514898941742274	[638]	[757,734,690,420]	-4	hSpCas9	negative selection	6577532
45711899	45711922	19	+	27260156	CORL105	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.2534636886347134	[540]	[447,516,724,462]	-5	hSpCas9	negative selection	6577533
45712241	45712264	19	+	27260156	CORL105	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.2994990775312058	[281]	[389,365,455,420]	5	hSpCas9	negative selection	6577534
45711772	45711795	19	-	27260156	HS294T	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.2762967375928388	[789]	[324,341,345,490]	4	hSpCas9	negative selection	6634519
45711815	45711838	19	+	27260156	HS294T	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.3725561524954095	[247]	[92,99,122,195]	5	hSpCas9	negative selection	6634520
45712916	45712939	19	+	27260156	HS294T	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.09517920349063214	[456]	[136,193,140,195]	-1	hSpCas9	negative selection	6634521
45712397	45712420	19	-	27260156	HS294T	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.2116294481608636	[638]	[186,501,198,251]	3	hSpCas9	negative selection	6698783
45711899	45711922	19	+	27260156	HS294T	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.24412386151711302	[540]	[138,135,238,200]	-3	hSpCas9	negative selection	6698784
45712241	45712264	19	+	27260156	HS294T	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.4379133856716623	[281]	[87,75,129,335]	6	hSpCas9	negative selection	6698785
45711772	45711795	19	-	27260156	HCC44	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.4830339479857627	[789]	[1183,1055,1575,1246]	7	hSpCas9	negative selection	6755770
45711815	45711838	19	+	27260156	HCC44	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.07529382632467663	[247]	[335,166,394,319]	1	hSpCas9	negative selection	6755771
45712916	45712939	19	+	27260156	HCC44	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.46821542561086593	[456]	[728,715,970,490]	7	hSpCas9	negative selection	6755772
45712397	45712420	19	-	27260156	HCC44	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.5137638314200861	[638]	[1211,708,1171,1109]	8	hSpCas9	negative selection	6820034
45711899	45711922	19	+	27260156	HCC44	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.33002306197703635	[540]	[796,546,1103,715]	5	hSpCas9	negative selection	6820035
45712241	45712264	19	+	27260156	HCC44	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.0290789951496373	[281]	[234,334,484,263]	0	hSpCas9	negative selection	6820036
45711772	45711795	19	-	27260156	G402	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.6484794043674439	[789]	[1482,1229,2072,1244]	7	hSpCas9	negative selection	6877021
45711815	45711838	19	+	27260156	G402	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.10048443582079147	[247]	[409,425,201,278]	1	hSpCas9	negative selection	6877022
45712916	45712939	19	+	27260156	G402	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.2812626987975566	[456]	[676,483,885,650]	3	hSpCas9	negative selection	6877023
45712397	45712420	19	-	27260156	G402	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.436674979990031	[638]	[903,465,565,414]	-5	hSpCas9	negative selection	6941285
45711899	45711922	19	+	27260156	G402	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.5039294142816718	[540]	[198,642,395,587]	-6	hSpCas9	negative selection	6941286
45712241	45712264	19	+	27260156	G402	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.4356140110036983	[281]	[610,681,402,209]	5	hSpCas9	negative selection	6941287
45711772	45711795	19	-	27260156	L33	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.34379923075055274	[789]	[926,461,595,1008]	7	hSpCas9	negative selection	6998272
45711815	45711838	19	+	27260156	L33	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.13535626909938359	[247]	[201,83,161,238]	-3	hSpCas9	negative selection	6998273
45712916	45712939	19	+	27260156	L33	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.3040434368062227	[456]	[507,271,324,568]	6	hSpCas9	negative selection	6998274
45712397	45712420	19	-	27260156	L33	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.2238656724797652	[638]	[493,297,328,445]	-5	hSpCas9	negative selection	7062536
45711899	45711922	19	+	27260156	L33	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.0030433553140324088	[540]	[557,194,407,476]	0	hSpCas9	negative selection	7062537
45712241	45712264	19	+	27260156	L33	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.15432471790361768	[281]	[313,155,222,206]	3	hSpCas9	negative selection	7062538
45711772	45711795	19	-	27260156	K562	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.1168682219369821	[789]	[749,869,1005,452]	1	hSpCas9	negative selection	7119523
45711815	45711838	19	+	27260156	K562	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.7662904358852477	[247]	[201,140,158,32]	-7	hSpCas9	negative selection	7119524
45712916	45712939	19	+	27260156	K562	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.6576637163258964	[456]	[276,476,1443,353]	8	hSpCas9	negative selection	7119525
45712397	45712420	19	-	27260156	K562	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.7285756928898381	[638]	[363,470,264,282]	-7	hSpCas9	negative selection	7183787
45711899	45711922	19	+	27260156	K562	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.17658569736524712	[540]	[680,424,325,300]	-2	hSpCas9	negative selection	7183788
45712241	45712264	19	+	27260156	K562	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.23676257745697082	[281]	[147,283,337,384]	3	hSpCas9	negative selection	7183789
45711772	45711795	19	-	27260156	HT29	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.0313292816348516	[789]	[951,1158,1094,753]	0	hSpCas9	negative selection	7240774
45711815	45711838	19	+	27260156	HT29	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.1639750015917324	[247]	[338,248,175,308]	-3	hSpCas9	negative selection	7240775
45712916	45712939	19	+	27260156	HT29	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.03281623312741157	[456]	[560,768,414,454]	0	hSpCas9	negative selection	7240776
45712397	45712420	19	-	27260156	HT29	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.020356196590481712	[638]	[898,827,736,703]	0	hSpCas9	negative selection	7305038
45711899	45711922	19	+	27260156	HT29	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.28924896259057886	[540]	[545,442,710,451]	-5	hSpCas9	negative selection	7305039
45712241	45712264	19	+	27260156	HT29	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.09366094955738546	[281]	[430,434,405,217]	1	hSpCas9	negative selection	7305040
45711772	45711795	19	-	27260156	MHHES1	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.35200497482105886	[789]	[1438,1187,1320,711]	6	hSpCas9	negative selection	7362025
45711815	45711838	19	+	27260156	MHHES1	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.19065585717937805	[247]	[358,428,237,268]	3	hSpCas9	negative selection	7362026
45712916	45712939	19	+	27260156	MHHES1	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.031632055642072	[456]	[692,324,550,450]	0	hSpCas9	negative selection	7362027
45712397	45712420	19	-	27260156	MHHES1	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.18174106675407792	[638]	[704,917,415,541]	-3	hSpCas9	negative selection	7426289
45711899	45711922	19	+	27260156	MHHES1	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.210122948306788	[540]	[851,535,808,625]	4	hSpCas9	negative selection	7426290
45712241	45712264	19	+	27260156	MHHES1	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	-0.015689384113633187	[281]	[366,307,286,296]	0	hSpCas9	negative selection	7426291
45711772	45711795	19	-	27260156	MEWO	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.18495065205862193	[789]	[940,819,778]	4	hSpCas9	negative selection	7483276
45711815	45711838	19	+	27260156	MEWO	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.03804632327988233	[247]	[269,311,103]	-1	hSpCas9	negative selection	7483277
45712916	45712939	19	+	27260156	MEWO	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.248053857364242	[456]	[552,494,483]	5	hSpCas9	negative selection	7483278
45712397	45712420	19	-	27260156	MEWO	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.02374194310785177	[638]	[718,535,589]	0	hSpCas9	negative selection	7547540
45711899	45711922	19	+	27260156	MEWO	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.05846663331297225	[540]	[708,321,470]	-1	hSpCas9	negative selection	7547541
45712241	45712264	19	+	27260156	MEWO	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.19882433694455026	[281]	[260,357,280]	4	hSpCas9	negative selection	7547542
45711772	45711795	19	-	27260156	LNCAPCLONEFGC	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.45938565763241124	[789]	[845,1005,1122,981]	7	hSpCas9	negative selection	7604527
45711815	45711838	19	+	27260156	LNCAPCLONEFGC	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.41856431433868113	[247]	[286,310,256,338]	6	hSpCas9	negative selection	7604528
45712916	45712939	19	+	27260156	LNCAPCLONEFGC	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.3360738717879404	[456]	[574,370,576,583]	5	hSpCas9	negative selection	7604529
45712397	45712420	19	-	27260156	LNCAPCLONEFGC	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.27563605732059626	[638]	[817,672,687,620]	4	hSpCas9	negative selection	7668791
45711899	45711922	19	+	27260156	LNCAPCLONEFGC	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.04982618602714492	[540]	[530,431,558,518]	0	hSpCas9	negative selection	7668792
45712241	45712264	19	+	27260156	LNCAPCLONEFGC	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.4885147516482644	[281]	[242,398,540,276]	7	hSpCas9	negative selection	7668793
45711772	45711795	19	-	27260156	PANC0327	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.3594608013528354	[789]	[1149,924,694,847]	5	hSpCas9	negative selection	7725778
45711815	45711838	19	+	27260156	PANC0327	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.33676760138687023	[247]	[195,123,195,189]	-5	hSpCas9	negative selection	7725779
45712916	45712939	19	+	27260156	PANC0327	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.161755356903033	[456]	[382,382,620,432]	2	hSpCas9	negative selection	7725780
45712397	45712420	19	-	27260156	PANC0327	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.3439846687693592	[638]	[546,339,564,358]	-5	hSpCas9	negative selection	7790042
45711899	45711922	19	+	27260156	PANC0327	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.16743410097035027	[540]	[347,481,431,435]	-2	hSpCas9	negative selection	7790043
45712241	45712264	19	+	27260156	PANC0327	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.29935899343838385	[281]	[348,224,294,377]	4	hSpCas9	negative selection	7790044
45711772	45711795	19	-	27260156	NCIH2009	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.34909202049183985	[789]	[1574,1448,1223]	5	hSpCas9	negative selection	7847029
45711815	45711838	19	+	27260156	NCIH2009	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.28317452606009896	[247]	[373,250,246]	-4	hSpCas9	negative selection	7847030
45712916	45712939	19	+	27260156	NCIH2009	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.2525384250420821	[456]	[1000,603,725]	3	hSpCas9	negative selection	7847031
45712397	45712420	19	-	27260156	NCIH2009	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.21106792116181453	[638]	[991,833,528]	-3	hSpCas9	negative selection	7911293
45711899	45711922	19	+	27260156	NCIH2009	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.2611757651801218	[540]	[808,534,583]	-4	hSpCas9	negative selection	7911294
45712241	45712264	19	+	27260156	NCIH2009	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.30248417935916894	[281]	[531,540,391]	4	hSpCas9	negative selection	7911295
45711772	45711795	19	-	27260156	NCIH1373	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.2510315513686575	[789]	[1267,1002,792,314]	2	hSpCas9	negative selection	7968280
45711815	45711838	19	+	27260156	NCIH1373	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.4032509497072777	[247]	[174,66,82,143]	-4	hSpCas9	negative selection	7968281
45712916	45712939	19	+	27260156	NCIH1373	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.040375416290633404	[456]	[430,388,591,152]	0	hSpCas9	negative selection	7968282
45712397	45712420	19	-	27260156	NCIH1373	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-1.1083260257342706	[638]	[362,253,292,114]	-8	hSpCas9	negative selection	8032544
45711899	45711922	19	+	27260156	NCIH1373	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.6549336185712592	[540]	[574,303,188,136]	-6	hSpCas9	negative selection	8032545
45712241	45712264	19	+	27260156	NCIH1373	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.9825752279797212	[281]	[1078,372,564,150]	8	hSpCas9	negative selection	8032546
45711772	45711795	19	-	27260156	PATU8902	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.535731774894768	[789]	[2166,1261,1332,1673]	5	hSpCas9	negative selection	8089531
45711815	45711838	19	+	27260156	PATU8902	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.09502635497497347	[247]	[370,143,613,266]	1	hSpCas9	negative selection	8089532
45712916	45712939	19	+	27260156	PATU8902	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.26679813952151527	[456]	[884,228,417,612]	-3	hSpCas9	negative selection	8089533
45712397	45712420	19	-	27260156	PATU8902	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.12080039184476343	[638]	[786,545,936,985]	-1	hSpCas9	negative selection	8153795
45711899	45711922	19	+	27260156	PATU8902	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.19176212378500984	[540]	[812,512,626,689]	-2	hSpCas9	negative selection	8153796
45712241	45712264	19	+	27260156	PATU8902	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.9348388059462104	[281]	[1002,474,559,1038]	8	hSpCas9	negative selection	8153797
45711772	45711795	19	-	27260156	PANC1	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.2710379651053515	[789]	[836,840,721,857]	4	hSpCas9	negative selection	8210782
45711815	45711838	19	+	27260156	PANC1	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.14900491803184024	[247]	[229,378,174,192]	2	hSpCas9	negative selection	8210783
45712916	45712939	19	+	27260156	PANC1	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.39726860090852606	[456]	[482,564,612,424]	6	hSpCas9	negative selection	8210784
45712397	45712420	19	-	27260156	PANC1	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.5968943770001134	[638]	[738,980,933,706]	8	hSpCas9	negative selection	8275046
45711899	45711922	19	+	27260156	PANC1	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.533437383555101	[540]	[535,908,777,531]	8	hSpCas9	negative selection	8275047
45712241	45712264	19	+	27260156	PANC1	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.4169670039935686	[281]	[334,407,300,269]	6	hSpCas9	negative selection	8275048
45711772	45711795	19	-	27260156	PANC0813	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.33029899448721156	[789]	[1280,1218,1133,1047]	5	hSpCas9	negative selection	8332033
45711815	45711838	19	+	27260156	PANC0813	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.18670307265784303	[247]	[481,250,319,288]	3	hSpCas9	negative selection	8332034
45712916	45712939	19	+	27260156	PANC0813	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.310077256785399	[456]	[652,613,741,651]	5	hSpCas9	negative selection	8332035
45712397	45712420	19	-	27260156	PANC0813	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.21997598192047477	[638]	[674,625,676,603]	-4	hSpCas9	negative selection	8396297
45711899	45711922	19	+	27260156	PANC0813	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.016127502902470114	[540]	[886,687,467,499]	0	hSpCas9	negative selection	8396298
45712241	45712264	19	+	27260156	PANC0813	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.4492549454392393	[281]	[368,484,600,351]	7	hSpCas9	negative selection	8396299
45711772	45711795	19	-	27260156	RDES	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.46407603319523905	[789]	[946,1113,1612,1421]	7	hSpCas9	negative selection	8453284
45711815	45711838	19	+	27260156	RDES	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.08571886108400795	[247]	[191,378,252,408]	1	hSpCas9	negative selection	8453285
45712916	45712939	19	+	27260156	RDES	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.2654792567173201	[456]	[496,641,690,721]	4	hSpCas9	negative selection	8453286
45712397	45712420	19	-	27260156	RDES	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.05950427891244969	[638]	[563,776,829,646]	-1	hSpCas9	negative selection	8517548
45711899	45711922	19	+	27260156	RDES	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.06955843418240176	[540]	[461,627,540,772]	-1	hSpCas9	negative selection	8517549
45712241	45712264	19	+	27260156	RDES	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.2544708656514527	[281]	[296,381,441,445]	4	hSpCas9	negative selection	8517550
45711772	45711795	19	-	27260156	PC3	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.20907114518154912	[789]	[739,749,1528,831]	4	hSpCas9	negative selection	8574535
45711815	45711838	19	+	27260156	PC3	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.49115455155073956	[247]	[216,361,712,258]	8	hSpCas9	negative selection	8574536
45712916	45712939	19	+	27260156	PC3	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.2926544167601809	[456]	[405,503,745,660]	6	hSpCas9	negative selection	8574537
45712397	45712420	19	-	27260156	PC3	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.016043828875754618	[638]	[263,846,972,673]	0	hSpCas9	negative selection	8638799
45711899	45711922	19	+	27260156	PC3	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.13717813917679636	[540]	[398,625,895,589]	3	hSpCas9	negative selection	8638800
45712241	45712264	19	+	27260156	PC3	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.1790206122744259	[281]	[247,239,556,318]	4	hSpCas9	negative selection	8638801
45711772	45711795	19	-	27260156	PATU8988T	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.15874464040921843	[789]	[814,1012,725,872]	2	hSpCas9	negative selection	8695786
45711815	45711838	19	+	27260156	PATU8988T	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.5114273191949745	[247]	[299,372,374,318]	8	hSpCas9	negative selection	8695787
45712916	45712939	19	+	27260156	PATU8988T	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.018234941401751387	[456]	[302,583,557,346]	0	hSpCas9	negative selection	8695788
45712397	45712420	19	-	27260156	PATU8988T	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.06859531503054805	[638]	[602,990,577,433]	1	hSpCas9	negative selection	8760050
45711899	45711922	19	+	27260156	PATU8988T	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.13760190740728498	[540]	[767,382,541,590]	2	hSpCas9	negative selection	8760051
45712241	45712264	19	+	27260156	PATU8988T	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.2953671157673565	[281]	[327,367,398,236]	5	hSpCas9	negative selection	8760052
45711772	45711795	19	-	27260156	T47D	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.2576767838279973	[789]	[1142,923,1106,1246]	5	hSpCas9	negative selection	8817037
45711815	45711838	19	+	27260156	T47D	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.21416658934324062	[247]	[459,216,384,286]	4	hSpCas9	negative selection	8817038
45712916	45712939	19	+	27260156	T47D	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.05052414360670779	[456]	[618,521,489,578]	1	hSpCas9	negative selection	8817039
45712397	45712420	19	-	27260156	T47D	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.14589252281690335	[638]	[753,584,683,675]	-3	hSpCas9	negative selection	8881301
45711899	45711922	19	+	27260156	T47D	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.14909081253706308	[540]	[483,531,612,648]	-3	hSpCas9	negative selection	8881302
45712241	45712264	19	+	27260156	T47D	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.09869314186073219	[281]	[399,283,391,335]	2	hSpCas9	negative selection	8881303
45711772	45711795	19	-	27260156	SU8686	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.23548837183479487	[789]	[840,947,1026,864]	4	hSpCas9	negative selection	8938288
45711815	45711838	19	+	27260156	SU8686	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.005084599592501737	[247]	[189,260,197,348]	0	hSpCas9	negative selection	8938289
45712916	45712939	19	+	27260156	SU8686	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.22766732462025047	[456]	[479,452,618,594]	4	hSpCas9	negative selection	8938290
45712397	45712420	19	-	27260156	SU8686	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.13165530150034632	[638]	[497,510,571,777]	-2	hSpCas9	negative selection	9002552
45711899	45711922	19	+	27260156	SU8686	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.1820530732817031	[540]	[619,513,625,694]	3	hSpCas9	negative selection	9002553
45712241	45712264	19	+	27260156	SU8686	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.3247457625294178	[281]	[400,328,331,328]	5	hSpCas9	negative selection	9002554
45711772	45711795	19	-	27260156	SKES1	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.39208966377172694	[789]	[974,1412,870,919]	7	hSpCas9	negative selection	9059539
45711815	45711838	19	+	27260156	SKES1	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.1971431262934521	[247]	[290,205,231,148]	-4	hSpCas9	negative selection	9059540
45712916	45712939	19	+	27260156	SKES1	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.20444872531783934	[456]	[559,574,484,490]	4	hSpCas9	negative selection	9059541
45712397	45712420	19	-	27260156	SKES1	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.05968060171264944	[638]	[956,611,719,423]	1	hSpCas9	negative selection	9123803
45711899	45711922	19	+	27260156	SKES1	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.22899576477372166	[540]	[474,522,394,454]	-5	hSpCas9	negative selection	9123804
45712241	45712264	19	+	27260156	SKES1	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.04563630336325564	[281]	[429,257,289,205]	1	hSpCas9	negative selection	9123805
45711772	45711795	19	-	27260156	TOV112D	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.13552290186208305	[789]	[985,1010,692,830]	2	hSpCas9	negative selection	9180790
45711815	45711838	19	+	27260156	TOV112D	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.13510865063631472	[247]	[248,327,188,166]	-3	hSpCas9	negative selection	9180791
45712916	45712939	19	+	27260156	TOV112D	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	-0.209445567129427	[456]	[423,401,340,418]	-4	hSpCas9	negative selection	9180792
45712397	45712420	19	-	27260156	TOV112D	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.1589847963093185	[638]	[684,1271,547,492]	3	hSpCas9	negative selection	9245054
45711899	45711922	19	+	27260156	TOV112D	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.33281744483197484	[540]	[496,566,394,303]	-6	hSpCas9	negative selection	9245055
45712241	45712264	19	+	27260156	TOV112D	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.2567848404797407	[281]	[250,301,432,346]	5	hSpCas9	negative selection	9245056
45711772	45711795	19	-	27260156	TC71	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.30336669740007116	[789]	[925,1151,980,1130]	7	hSpCas9	negative selection	9302041
45711815	45711838	19	+	27260156	TC71	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	0.13464974166056887	[247]	[275,334,181,383]	3	hSpCas9	negative selection	9302042
45712916	45712939	19	+	27260156	TC71	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.10173860626721795	[456]	[496,481,565,558]	2	hSpCas9	negative selection	9302043
45712397	45712420	19	-	27260156	TC71	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	0.08627191904535947	[638]	[899,708,571,728]	2	hSpCas9	negative selection	9366305
45711899	45711922	19	+	27260156	TC71	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	0.09148150310479722	[540]	[733,536,591,605]	2	hSpCas9	negative selection	9366306
45712241	45712264	19	+	27260156	TC71	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.09247770168164549	[281]	[331,304,256,401]	2	hSpCas9	negative selection	9366307
45711772	45711795	19	-	27260156	TC32	viability	CGAGCCGACCGCGAGACTCCCGG	FBXO46	ENSG00000177051	0.29069761559335927	[789]	[871,677,1190,981]	5	hSpCas9	negative selection	9423292
45711815	45711838	19	+	27260156	TC32	viability	AACGTCCGTAAGGCAGGTCATGG	FBXO46	ENSG00000177051	-0.016215767772324252	[247]	[171,185,339,254]	0	hSpCas9	negative selection	9423293
45712916	45712939	19	+	27260156	TC32	viability	TCGGTCGTGGGTAGCTCTGCAGG	FBXO46	ENSG00000177051	0.2535872995453527	[456]	[407,554,597,461]	4	hSpCas9	negative selection	9423294
45712397	45712420	19	-	27260156	TC32	viability	CGGAGCGTCAGGCTTCCACGTGG	FBXO46	ENSG00000177051	-0.06580402293102466	[638]	[624,392,753,581]	-1	hSpCas9	negative selection	9487556
45711899	45711922	19	+	27260156	TC32	viability	ACTGTTTGCACGGATCATCGCGG	FBXO46	ENSG00000177051	-0.3013362533945173	[540]	[437,202,621,480]	-5	hSpCas9	negative selection	9487557
45712241	45712264	19	+	27260156	TC32	viability	GCCCGTCCGGCCCGCGGTTCTGG	FBXO46	ENSG00000177051	0.23341524047848405	[281]	[294,277,392,287]	4	hSpCas9	negative selection	9487558
45712142	45712165	19	+	27869803	HPAFII	viability after 27 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	2.387639468126558	[18]	[108,4,NaN]	9	hSpCas9	negative selection	9568555
45712146	45712169	19	+	27869803	HPAFII	viability after 27 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.15256480282273477	[389]	[216,236,NaN]	1	hSpCas9	negative selection	9568556
45712247	45712270	19	-	27869803	HPAFII	viability after 27 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.3039404067743846	[121]	[70,85,NaN]	2	hSpCas9	negative selection	9568557
45712688	45712711	19	-	27869803	HPAFII	viability after 27 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	1.19867713227347	[145]	[329,47,NaN]	8	hSpCas9	negative selection	9568558
45712862	45712885	19	-	27869803	HPAFII	viability after 27 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	-0.45644376160357136	[614]	[281,196,NaN]	-3	hSpCas9	negative selection	9568559
45712888	45712911	19	+	27869803	HPAFII	viability after 27 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.6688320670889911	[206]	[146,2,NaN]	-5	hSpCas9	negative selection	9568560
45712142	45712165	19	+	27869803	HPAFII	viability after 15 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	-0.5207120720228513	[18]	[12,14,NaN]	-5	hSpCas9	negative selection	9651004
45712146	45712169	19	+	27869803	HPAFII	viability after 15 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.1758849489742348	[389]	[584,237,NaN]	-2	hSpCas9	negative selection	9651005
45712247	45712270	19	-	27869803	HPAFII	viability after 15 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.4295346481307155	[121]	[228,143,NaN]	5	hSpCas9	negative selection	9651006
45712688	45712711	19	-	27869803	HPAFII	viability after 15 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.5985889994916181	[145]	[176,57,NaN]	-6	hSpCas9	negative selection	9651007
45712862	45712885	19	-	27869803	HPAFII	viability after 15 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	-0.12686318049073986	[614]	[637,584,NaN]	-1	hSpCas9	negative selection	9651008
45712888	45712911	19	+	27869803	HPAFII	viability after 15 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.5839834271715234	[206]	[288,60,NaN]	-6	hSpCas9	negative selection	9651009
45712142	45712165	19	+	27869803	ASPC1	viability after 36 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	-0.9565737064450559	[103]	[57,0,4]	-7	hSpCas9	negative selection	9733453
45712146	45712169	19	+	27869803	ASPC1	viability after 36 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.26291013678628006	[583]	[144,275,286]	2	hSpCas9	negative selection	9733454
45712247	45712270	19	-	27869803	ASPC1	viability after 36 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.31811812323308697	[249]	[233,66,52]	3	hSpCas9	negative selection	9733455
45712688	45712711	19	-	27869803	ASPC1	viability after 36 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.05948857038971056	[355]	[257,109,27]	0	hSpCas9	negative selection	9733456
45712862	45712885	19	-	27869803	ASPC1	viability after 36 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.373356778190303	[1113]	[581,487,455]	4	hSpCas9	negative selection	9733457
45712888	45712911	19	+	27869803	ASPC1	viability after 36 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	0.15626000840158172	[277]	[118,90,112]	1	hSpCas9	negative selection	9733458
45712142	45712165	19	+	27869803	PATU8988S	viability after 35 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.18601388057726753	[35]	[13,18,NaN]	2	hSpCas9	negative selection	9815902
45712146	45712169	19	+	27869803	PATU8988S	viability after 35 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.24368668087748221	[621]	[343,248,NaN]	3	hSpCas9	negative selection	9815903
45712247	45712270	19	-	27869803	PATU8988S	viability after 35 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	1.269544958944112	[217]	[286,135,NaN]	9	hSpCas9	negative selection	9815904
45712688	45712711	19	-	27869803	PATU8988S	viability after 35 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	-0.37727518563891704	[318]	[60,136,NaN]	-4	hSpCas9	negative selection	9815905
45712862	45712885	19	-	27869803	PATU8988S	viability after 35 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.6666992793517865	[1216]	[592,963,NaN]	7	hSpCas9	negative selection	9815906
45712888	45712911	19	+	27869803	PATU8988S	viability after 35 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.7186440347001202	[367]	[117,61,NaN]	-6	hSpCas9	negative selection	9815907
45712142	45712165	19	+	27869803	PATU8988S	viability after 31 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.6159738086449891	[35]	[21,21,NaN]	7	hSpCas9	negative selection	9898351
45712146	45712169	19	+	27869803	PATU8988S	viability after 31 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.3701270234099341	[621]	[298,347,NaN]	4	hSpCas9	negative selection	9898352
45712247	45712270	19	-	27869803	PATU8988S	viability after 31 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.8272981966895037	[217]	[144,165,NaN]	8	hSpCas9	negative selection	9898353
45712688	45712711	19	-	27869803	PATU8988S	viability after 31 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.12287941256171808	[318]	[79,212,NaN]	1	hSpCas9	negative selection	9898354
45712862	45712885	19	-	27869803	PATU8988S	viability after 31 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	0.8442356618097058	[1216]	[740,1036,NaN]	8	hSpCas9	negative selection	9898355
45712888	45712911	19	+	27869803	PATU8988S	viability after 31 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.7561832339405095	[367]	[74,101,NaN]	-7	hSpCas9	negative selection	9898356
45712142	45712165	19	+	27869803	HPAFII	viability after 35 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	0.7079066099178597	[18]	[26,2,NaN]	4	hSpCas9	negative selection	9980800
45712146	45712169	19	+	27869803	HPAFII	viability after 35 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	-0.2301437285024498	[389]	[109,233,NaN]	-1	hSpCas9	negative selection	9980801
45712247	45712270	19	-	27869803	HPAFII	viability after 35 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	-0.08811382464943196	[121]	[27,91,NaN]	0	hSpCas9	negative selection	9980802
45712688	45712711	19	-	27869803	HPAFII	viability after 35 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.7570443155921688	[145]	[186,54,NaN]	5	hSpCas9	negative selection	9980803
45712862	45712885	19	-	27869803	HPAFII	viability after 35 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	-0.5374803336944777	[614]	[166,267,NaN]	-3	hSpCas9	negative selection	9980804
45712888	45712911	19	+	27869803	HPAFII	viability after 35 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-1.4585273281149302	[206]	[63,8,NaN]	-7	hSpCas9	negative selection	9980805
45712142	45712165	19	+	27869803	HPAFII	viability after 31 days	CGTGCCGGTACAAGCGGCACAGG	FBXO46	ENSG00000177051	1.8923516647681227	[18]	[74,0,NaN]	9	hSpCas9	negative selection	10063249
45712146	45712169	19	+	27869803	HPAFII	viability after 31 days	CCGGTACAAGCGGCACAGGGAGG	FBXO46	ENSG00000177051	0.05181742929574429	[389]	[212,241,NaN]	0	hSpCas9	negative selection	10063250
45712247	45712270	19	-	27869803	HPAFII	viability after 31 days	CTTTCTCCAGAACCGCGGGCCGG	FBXO46	ENSG00000177051	0.22185436463624175	[121]	[42,119,NaN]	1	hSpCas9	negative selection	10063251
45712688	45712711	19	-	27869803	HPAFII	viability after 31 days	CTTCCGCATCTCCAACGGCCGGG	FBXO46	ENSG00000177051	0.8154025303788588	[145]	[248,29,NaN]	6	hSpCas9	negative selection	10063252
45712862	45712885	19	-	27869803	HPAFII	viability after 31 days	CGAGCAAGGTGGACCGGCCAAGG	FBXO46	ENSG00000177051	-0.655014424943875	[614]	[256,177,NaN]	-4	hSpCas9	negative selection	10063253
45712888	45712911	19	+	27869803	HPAFII	viability after 31 days	GACACAAAGACTACAGGCGCTGG	FBXO46	ENSG00000177051	-0.8421938498268051	[206]	[104,20,NaN]	-5	hSpCas9	negative selection	10063254
45712808	45712831	19	-	28162770	P31FUJ	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.7529839363659201	[50]	[100]	8	hSpCas9	negative selection	10156170
45712270	45712293	19	+	28162770	P31FUJ	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.8028914286540048	[192]	[129]	-6	hSpCas9	negative selection	10156171
45713434	45713457	19	+	28162770	P31FUJ	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	-0.23280220441437877	[224]	[224]	-2	hSpCas9	negative selection	10156172
45713263	45713286	19	+	28162770	P31FUJ	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-1.5231947258686342	[180]	[73]	-7	hSpCas9	negative selection	10156173
45713094	45713117	19	-	28162770	P31FUJ	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.2005618674141707	[176]	[180]	-2	hSpCas9	negative selection	10156174
45712834	45712857	19	-	28162770	P31FUJ	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.6823088979991083	[34]	[65]	7	hSpCas9	negative selection	10156175
45712743	45712766	19	-	28162770	P31FUJ	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	0.2266294142229185	[175]	[241]	2	hSpCas9	negative selection	10156176
45712666	45712689	19	-	28162770	P31FUJ	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.04244167966653656	[552]	[630]	0	hSpCas9	negative selection	10156177
45712517	45712540	19	+	28162770	P31FUJ	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.44495544124598846	[350]	[302]	-4	hSpCas9	negative selection	10156178
45712328	45712351	19	-	28162770	P31FUJ	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-0.10922751929584597	[245]	[267]	-1	hSpCas9	negative selection	10156179
45712808	45712831	19	-	28162770	TF1	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10325536
45712270	45712293	19	+	28162770	TF1	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10325537
45713434	45713457	19	+	28162770	TF1	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10325538
45713263	45713286	19	+	28162770	TF1	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10325539
45713094	45713117	19	-	28162770	TF1	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10325540
45712834	45712857	19	-	28162770	TF1	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10325541
45712743	45712766	19	-	28162770	TF1	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10325542
45712666	45712689	19	-	28162770	TF1	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	NaN	[NaN]	[568]	1	hSpCas9	negative selection	10325543
45712517	45712540	19	+	28162770	TF1	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10325544
45712328	45712351	19	-	28162770	TF1	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10325545
45712808	45712831	19	-	28162770	SKM1	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	1.6185708933639757	[13]	[75]	9	hSpCas9	negative selection	10494902
45712270	45712293	19	+	28162770	SKM1	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.18457177740671377	[44]	[69]	-1	hSpCas9	negative selection	10494903
45713434	45713457	19	+	28162770	SKM1	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.2760303849385213	[63]	[136]	2	hSpCas9	negative selection	10494904
45713263	45713286	19	+	28162770	SKM1	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	0.016717394944933753	[51]	[92]	0	hSpCas9	negative selection	10494905
45713094	45713117	19	-	28162770	SKM1	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	0.44103270781178816	[44]	[107]	4	hSpCas9	negative selection	10494906
45712834	45712857	19	-	28162770	SKM1	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-1.0025739436638264	[16]	[14]	-6	hSpCas9	negative selection	10494907
45712743	45712766	19	-	28162770	SKM1	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	0.9180301991919841	[46]	[156]	8	hSpCas9	negative selection	10494908
45712666	45712689	19	-	28162770	SKM1	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.26599057099697854	[150]	[221]	-2	hSpCas9	negative selection	10494909
45712517	45712540	19	+	28162770	SKM1	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.07197995103035293	[87]	[147]	0	hSpCas9	negative selection	10494910
45712328	45712351	19	-	28162770	SKM1	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-0.31950135749282227	[47]	[67]	-3	hSpCas9	negative selection	10494911
45712808	45712831	19	-	28162770	SKM1	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	1.6185708933639757	[13]	[75]	9	hSpCas9	negative selection	10664268
45712270	45712293	19	+	28162770	SKM1	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.18457177740671377	[44]	[69]	-1	hSpCas9	negative selection	10664269
45713434	45713457	19	+	28162770	SKM1	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.2760303849385213	[63]	[136]	2	hSpCas9	negative selection	10664270
45713263	45713286	19	+	28162770	SKM1	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	0.016717394944933753	[51]	[92]	0	hSpCas9	negative selection	10664271
45713094	45713117	19	-	28162770	SKM1	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	0.44103270781178816	[44]	[107]	4	hSpCas9	negative selection	10664272
45712834	45712857	19	-	28162770	SKM1	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-1.0025739436638264	[16]	[14]	-6	hSpCas9	negative selection	10664273
45712743	45712766	19	-	28162770	SKM1	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	0.9180301991919841	[46]	[156]	8	hSpCas9	negative selection	10664274
45712666	45712689	19	-	28162770	SKM1	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.26599057099697854	[150]	[221]	-2	hSpCas9	negative selection	10664275
45712517	45712540	19	+	28162770	SKM1	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.07197995103035293	[87]	[147]	0	hSpCas9	negative selection	10664276
45712328	45712351	19	-	28162770	SKM1	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-0.31950135749282227	[47]	[67]	-3	hSpCas9	negative selection	10664277
45712808	45712831	19	-	28162770	PL21	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.8846377887613909	[55]	[44]	7	hSpCas9	negative selection	10833634
45712270	45712293	19	+	28162770	PL21	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.10072686487021265	[169]	[68]	0	hSpCas9	negative selection	10833635
45713434	45713457	19	+	28162770	PL21	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.9505835930944121	[276]	[232]	7	hSpCas9	negative selection	10833636
45713263	45713286	19	+	28162770	PL21	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-1.2270316404253792	[198]	[36]	-7	hSpCas9	negative selection	10833637
45713094	45713117	19	-	28162770	PL21	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-1.7484612330040357	[192]	[24]	-8	hSpCas9	negative selection	10833638
45712834	45712857	19	-	28162770	PL21	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.3023607260398631	[33]	[11]	-2	hSpCas9	negative selection	10833639
45712743	45712766	19	-	28162770	PL21	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-1.3088740329985373	[147]	[25]	-7	hSpCas9	negative selection	10833640
45712666	45712689	19	-	28162770	PL21	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	0.3362763024753491	[383]	[210]	3	hSpCas9	negative selection	10833641
45712517	45712540	19	+	28162770	PL21	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.12942854260017406	[283]	[112]	-1	hSpCas9	negative selection	10833642
45712328	45712351	19	-	28162770	PL21	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	0.18306610113037863	[169]	[83]	1	hSpCas9	negative selection	10833643
45712808	45712831	19	-	28162770	P31FUJ	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.7529839363659201	[50]	[100]	8	hSpCas9	negative selection	11003000
45712270	45712293	19	+	28162770	P31FUJ	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.8028914286540048	[192]	[129]	-6	hSpCas9	negative selection	11003001
45713434	45713457	19	+	28162770	P31FUJ	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	-0.23280220441437877	[224]	[224]	-2	hSpCas9	negative selection	11003002
45713263	45713286	19	+	28162770	P31FUJ	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-1.5231947258686342	[180]	[73]	-7	hSpCas9	negative selection	11003003
45713094	45713117	19	-	28162770	P31FUJ	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.2005618674141707	[176]	[180]	-2	hSpCas9	negative selection	11003004
45712834	45712857	19	-	28162770	P31FUJ	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.6823088979991083	[34]	[65]	7	hSpCas9	negative selection	11003005
45712743	45712766	19	-	28162770	P31FUJ	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	0.2266294142229185	[175]	[241]	2	hSpCas9	negative selection	11003006
45712666	45712689	19	-	28162770	P31FUJ	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.04244167966653656	[552]	[630]	0	hSpCas9	negative selection	11003007
45712517	45712540	19	+	28162770	P31FUJ	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.44495544124598846	[350]	[302]	-4	hSpCas9	negative selection	11003008
45712328	45712351	19	-	28162770	P31FUJ	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-0.10922751929584597	[245]	[267]	-1	hSpCas9	negative selection	11003009
45712808	45712831	19	-	28162770	OCIAML5	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.6461842966638284	[39]	[112]	5	hSpCas9	negative selection	11172366
45712270	45712293	19	+	28162770	OCIAML5	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.9200849942926479	[151]	[144]	-5	hSpCas9	negative selection	11172367
45713434	45713457	19	+	28162770	OCIAML5	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.8662833451348623	[116]	[384]	7	hSpCas9	negative selection	11172368
45713263	45713286	19	+	28162770	OCIAML5	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.16175106999661232	[87]	[141]	-1	hSpCas9	negative selection	11172369
45713094	45713117	19	-	28162770	OCIAML5	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.6128789069845708	[60]	[71]	-4	hSpCas9	negative selection	11172370
45712834	45712857	19	-	28162770	OCIAML5	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-2.0891057681648464	[32]	[13]	-8	hSpCas9	negative selection	11172371
45712743	45712766	19	-	28162770	OCIAML5	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-4.2599472664606175e-05	[158]	[286]	0	hSpCas9	negative selection	11172372
45712666	45712689	19	-	28162770	OCIAML5	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	0.2535736042104533	[282]	[608]	2	hSpCas9	negative selection	11172373
45712517	45712540	19	+	28162770	OCIAML5	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	0.5762233351287619	[148]	[400]	5	hSpCas9	negative selection	11172374
45712328	45712351	19	-	28162770	OCIAML5	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-0.2186055524516509	[155]	[241]	-2	hSpCas9	negative selection	11172375
45712808	45712831	19	-	28162770	EOL1	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.49103761222021214	[130]	[96]	4	hSpCas9	negative selection	11341732
45712270	45712293	19	+	28162770	EOL1	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-1.4844659400805393	[238]	[44]	-7	hSpCas9	negative selection	11341733
45713434	45713457	19	+	28162770	EOL1	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.47967504275092776	[455]	[334]	4	hSpCas9	negative selection	11341734
45713263	45713286	19	+	28162770	EOL1	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.31439095864579625	[379]	[160]	-2	hSpCas9	negative selection	11341735
45713094	45713117	19	-	28162770	EOL1	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-1.062031712667144	[320]	[80]	-6	hSpCas9	negative selection	11341736
45712834	45712857	19	-	28162770	EOL1	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.04630588276994896	[146]	[74]	0	hSpCas9	negative selection	11341737
45712743	45712766	19	-	28162770	EOL1	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-0.002285815867493879	[172]	[90]	0	hSpCas9	negative selection	11341738
45712666	45712689	19	-	28162770	EOL1	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.5449375117306857	[539]	[194]	-4	hSpCas9	negative selection	11341739
45712517	45712540	19	+	28162770	EOL1	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.4689886584973872	[443]	[168]	-3	hSpCas9	negative selection	11341740
45712328	45712351	19	-	28162770	EOL1	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	0.43301213481764733	[141]	[100]	4	hSpCas9	negative selection	11341741
45712808	45712831	19	-	28162770	MOLM13	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.5157179066351938	[88]	[91]	4	hSpCas9	negative selection	11511098
45712270	45712293	19	+	28162770	MOLM13	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.7324092689412525	[215]	[93]	-4	hSpCas9	negative selection	11511099
45713434	45713457	19	+	28162770	MOLM13	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.31691348290325666	[311]	[280]	2	hSpCas9	negative selection	11511100
45713263	45713286	19	+	28162770	MOLM13	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-1.8122185376481563	[271]	[55]	-7	hSpCas9	negative selection	11511101
45713094	45713117	19	-	28162770	MOLM13	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.06412423922761834	[213]	[147]	0	hSpCas9	negative selection	11511102
45712834	45712857	19	-	28162770	MOLM13	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-1.6297214150818433	[106]	[24]	-7	hSpCas9	negative selection	11511103
45712743	45712766	19	-	28162770	MOLM13	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-0.7320481889641729	[254]	[110]	-4	hSpCas9	negative selection	11511104
45712666	45712689	19	-	28162770	MOLM13	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.6454924178731638	[687]	[317]	-4	hSpCas9	negative selection	11511105
45712517	45712540	19	+	28162770	MOLM13	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	0.14351119542432755	[441]	[352]	1	hSpCas9	negative selection	11511106
45712328	45712351	19	-	28162770	MOLM13	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-1.3524045962205231	[391]	[110]	-6	hSpCas9	negative selection	11511107
45712808	45712831	19	-	28162770	HEL	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	1.0577763312792006	[71]	[95]	8	hSpCas9	negative selection	11680464
45712270	45712293	19	+	28162770	HEL	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.24360438620407598	[182]	[98]	-2	hSpCas9	negative selection	11680465
45713434	45713457	19	+	28162770	HEL	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.6995248580919342	[273]	[284]	6	hSpCas9	negative selection	11680466
45713263	45713286	19	+	28162770	HEL	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.29755492187537547	[283]	[147]	-2	hSpCas9	negative selection	11680467
45713094	45713117	19	-	28162770	HEL	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.18672679166299566	[262]	[147]	-1	hSpCas9	negative selection	11680468
45712834	45712857	19	-	28162770	HEL	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-1.2641517636081618	[74]	[19]	-6	hSpCas9	negative selection	11680469
45712743	45712766	19	-	28162770	HEL	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-0.09197078822548119	[212]	[127]	0	hSpCas9	negative selection	11680470
45712666	45712689	19	-	28162770	HEL	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	0.5081527916327164	[493]	[449]	4	hSpCas9	negative selection	11680471
45712517	45712540	19	+	28162770	HEL	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	0.6051420453427053	[310]	[302]	5	hSpCas9	negative selection	11680472
45712328	45712351	19	-	28162770	HEL	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-1.1390809979501095	[195]	[56]	-6	hSpCas9	negative selection	11680473
45712808	45712831	19	-	28162770	MV411	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.4608411888919687	[68]	[79]	4	hSpCas9	negative selection	11849830
45712270	45712293	19	+	28162770	MV411	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-1.1234001445855335	[149]	[57]	-6	hSpCas9	negative selection	11849831
45713434	45713457	19	+	28162770	MV411	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.1498822413601016	[259]	[242]	1	hSpCas9	negative selection	11849832
45713263	45713286	19	+	28162770	MV411	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-1.3437569036498955	[231]	[76]	-7	hSpCas9	negative selection	11849833
45713094	45713117	19	-	28162770	MV411	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-1.4034882123167394	[178]	[56]	-7	hSpCas9	negative selection	11849834
45712834	45712857	19	-	28162770	MV411	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-2.1124583943036077	[76]	[14]	-8	hSpCas9	negative selection	11849835
45712743	45712766	19	-	28162770	MV411	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	0.16497539059080235	[143]	[135]	1	hSpCas9	negative selection	11849836
45712666	45712689	19	-	28162770	MV411	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	0.02622332064360866	[407]	[349]	0	hSpCas9	negative selection	11849837
45712517	45712540	19	+	28162770	MV411	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.4647601382344886	[230]	[140]	-3	hSpCas9	negative selection	11849838
45712328	45712351	19	-	28162770	MV411	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-0.14096482199260174	[160]	[122]	-1	hSpCas9	negative selection	11849839
45712808	45712831	19	-	28162770	MONOMAC1	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	-0.10392744266807208	[44]	[47]	-1	hSpCas9	negative selection	12019196
45712270	45712293	19	+	28162770	MONOMAC1	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.5698461109491001	[100]	[77]	-5	hSpCas9	negative selection	12019197
45713434	45713457	19	+	28162770	MONOMAC1	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	0.7876423536566903	[141]	[280]	7	hSpCas9	negative selection	12019198
45713263	45713286	19	+	28162770	MONOMAC1	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.2636345957885775	[132]	[126]	-2	hSpCas9	negative selection	12019199
45713094	45713117	19	-	28162770	MONOMAC1	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.3428877135230087	[103]	[93]	-3	hSpCas9	negative selection	12019200
45712834	45712857	19	-	28162770	MONOMAC1	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-0.5449601504798607	[27]	[21]	-4	hSpCas9	negative selection	12019201
45712743	45712766	19	-	28162770	MONOMAC1	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	-0.07946725067837773	[105]	[114]	0	hSpCas9	negative selection	12019202
45712666	45712689	19	-	28162770	MONOMAC1	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.0753582904713016	[249]	[271]	0	hSpCas9	negative selection	12019203
45712517	45712540	19	+	28162770	MONOMAC1	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	0.0126343331755151	[178]	[206]	0	hSpCas9	negative selection	12019204
45712328	45712351	19	-	28162770	MONOMAC1	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-1.484613437156139	[82]	[33]	-8	hSpCas9	negative selection	12019205
45712808	45712831	19	-	28162770	OCIAML2	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	0.607372686759112	[8]	[75]	6	hSpCas9	negative selection	12188562
45712270	45712293	19	+	28162770	OCIAML2	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.7787521206044932	[25]	[83]	-5	hSpCas9	negative selection	12188563
45713434	45713457	19	+	28162770	OCIAML2	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	-0.025844982569265595	[53]	[293]	0	hSpCas9	negative selection	12188564
45713263	45713286	19	+	28162770	OCIAML2	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.29660042546711235	[38]	[175]	-2	hSpCas9	negative selection	12188565
45713094	45713117	19	-	28162770	OCIAML2	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	-0.631566043457219	[44]	[160]	-5	hSpCas9	negative selection	12188566
45712834	45712857	19	-	28162770	OCIAML2	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	0.607372686759112	[8]	[75]	6	hSpCas9	negative selection	12188567
45712743	45712766	19	-	28162770	OCIAML2	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	0.13082079826756385	[28]	[175]	1	hSpCas9	negative selection	12188568
45712666	45712689	19	-	28162770	OCIAML2	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	-0.25676147621225165	[96]	[449]	-2	hSpCas9	negative selection	12188569
45712517	45712540	19	+	28162770	OCIAML2	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.7264687296717509	[59]	[200]	-5	hSpCas9	negative selection	12188570
45712328	45712351	19	-	28162770	OCIAML2	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	-0.816126391267928	[26]	[84]	-5	hSpCas9	negative selection	12188571
45712808	45712831	19	-	28162770	OCIAML3	viability	GGACTGCAGCCGTGTAGCCGAGG	FBXO46	ENSG00000177051	-0.24351039324003	[19]	[50]	-2	hSpCas9	negative selection	12357928
45712270	45712293	19	+	28162770	OCIAML3	viability	AAGAGCTGGCCCGGAGGCGGCGG	FBXO46	ENSG00000177051	-0.31602289302439807	[39]	[96]	-2	hSpCas9	negative selection	12357929
45713434	45713457	19	+	28162770	OCIAML3	viability	GAGTAGGTGCCAAAGGGCCGGGG	FBXO46	ENSG00000177051	-0.6751444030495686	[63]	[120]	-5	hSpCas9	negative selection	12357930
45713263	45713286	19	+	28162770	OCIAML3	viability	GCAGCTGCTGCTGAGAGGAGCGG	FBXO46	ENSG00000177051	-0.8187139274988575	[51]	[88]	-6	hSpCas9	negative selection	12357931
45713094	45713117	19	-	28162770	OCIAML3	viability	ATAGCTCCAAGGCCAAGCGGCGG	FBXO46	ENSG00000177051	1.0898082473232782	[46]	[301]	8	hSpCas9	negative selection	12357932
45712834	45712857	19	-	28162770	OCIAML3	viability	GGATCTGAACGGCGGTCCGGTGG	FBXO46	ENSG00000177051	-2.816400061660611	[27]	[11]	-9	hSpCas9	negative selection	12357933
45712743	45712766	19	-	28162770	OCIAML3	viability	AGGGCCTCCGCAAGGAAGAGCGG	FBXO46	ENSG00000177051	1.1159131308278143	[34]	[228]	8	hSpCas9	negative selection	12357934
45712666	45712689	19	-	28162770	OCIAML3	viability	GAGCCCCGTGCACCAGACAGCGG	FBXO46	ENSG00000177051	0.21534685937978948	[102]	[360]	2	hSpCas9	negative selection	12357935
45712517	45712540	19	+	28162770	OCIAML3	viability	GCAGGAACTCCACGTTGCTGGGG	FBXO46	ENSG00000177051	-0.38195716320917417	[59]	[138]	-3	hSpCas9	negative selection	12357936
45712328	45712351	19	-	28162770	OCIAML3	viability	GGACGGCACCAAGAACGTGAAGG	FBXO46	ENSG00000177051	0.015407904121532146	[38]	[118]	0	hSpCas9	negative selection	12357937