Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:55294
• Symbol:FBXW7
• Description:F-box and WD repeat domain containing 7

DataSource: http://genomecrispr.dkfz.de/#!/results/FBXW7

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
152328358	152328381	4	-	26472758	Jiyoye	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	0.2798710572307952	[295]	[270]	2	hSpCas9	negative selection	57022
152326111	152326134	4	-	26472758	Jiyoye	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.028663758252143623	[272]	[209]	0	hSpCas9	negative selection	57023
152328219	152328242	4	+	26472758	Jiyoye	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	1.4630286162393908	[37]	[78]	8	hSpCas9	negative selection	57024
152326186	152326209	4	+	26472758	Jiyoye	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	1.6595625431401588	[67]	[161]	8	hSpCas9	negative selection	57025
152347006	152347029	4	-	26472758	Jiyoye	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	2.675664217431775	[43]	[211]	9	hSpCas9	negative selection	57026
152332596	152332619	4	-	26472758	Jiyoye	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	0.6854765439929776	[140]	[170]	5	hSpCas9	negative selection	57027
152326033	152326056	4	-	26472758	Jiyoye	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	0.7165034396136022	[45]	[56]	5	hSpCas9	negative selection	57028
152347047	152347070	4	+	26472758	Jiyoye	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.05884604649177527	[191]	[138]	0	hSpCas9	negative selection	57029
152328288	152328311	4	-	26472758	Jiyoye	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-1.185522767994888	[186]	[61]	-7	hSpCas9	negative selection	57030
152328358	152328381	4	-	26472758	KBM7	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.7736721935733601	[932,634]	[278,152]	-6	hSpCas9	negative selection	248140
152326111	152326134	4	-	26472758	KBM7	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.02930900792475044	[955,1148]	[677,363]	0	hSpCas9	negative selection	248141
152328219	152328242	4	+	26472758	KBM7	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-0.6819660983215774	[251,271]	[115,42]	-5	hSpCas9	negative selection	248142
152326186	152326209	4	+	26472758	KBM7	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-1.7621214674929555	[511,355]	[99,22]	-8	hSpCas9	negative selection	248143
152347006	152347029	4	-	26472758	KBM7	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-1.9631674298523576	[725,311]	[53,65]	-8	hSpCas9	negative selection	248144
152332596	152332619	4	-	26472758	KBM7	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	-0.24828184185951083	[541,342]	[209,137]	-2	hSpCas9	negative selection	248145
152326033	152326056	4	-	26472758	KBM7	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-2.391674203149973	[266,286]	[14,33]	-9	hSpCas9	negative selection	248146
152347047	152347070	4	+	26472758	KBM7	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.5876959896821348	[590,517]	[18,146]	-8	hSpCas9	negative selection	248147
152328288	152328311	4	-	26472758	KBM7	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-2.5188844832499226	[310,340]	[26,26]	-9	hSpCas9	negative selection	248148
152328358	152328381	4	-	26472758	Raji	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-1.869047993487996	[424]	[26]	-8	hSpCas9	negative selection	439258
152326111	152326134	4	-	26472758	Raji	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.8160826164371018	[568]	[74]	-6	hSpCas9	negative selection	439259
152328219	152328242	4	+	26472758	Raji	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-0.42866936486661045	[86]	[14]	-4	hSpCas9	negative selection	439260
152326186	152326209	4	+	26472758	Raji	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-2.396747890734512	[294]	[12]	-9	hSpCas9	negative selection	439261
152347006	152347029	4	-	26472758	Raji	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-0.8408339225238541	[300]	[38]	-6	hSpCas9	negative selection	439262
152332596	152332619	4	-	26472758	Raji	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	-0.45333141910087954	[176]	[29]	-4	hSpCas9	negative selection	439263
152326033	152326056	4	-	26472758	Raji	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-3.507326308741609	[146]	[2]	-9	hSpCas9	negative selection	439264
152347047	152347070	4	+	26472758	Raji	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.5014257073019246	[243]	[19]	-8	hSpCas9	negative selection	439265
152328288	152328311	4	-	26472758	Raji	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-2.4974785227852614	[145]	[5]	-9	hSpCas9	negative selection	439266
152328358	152328381	4	-	26472758	K562	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.3534828287622075	[615]	[406]	-2	hSpCas9	negative selection	630376
152326111	152326134	4	-	26472758	K562	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.8548482625722301	[766]	[357]	-5	hSpCas9	negative selection	630377
152328219	152328242	4	+	26472758	K562	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-1.3949915570770859	[242]	[77]	-6	hSpCas9	negative selection	630378
152326186	152326209	4	+	26472758	K562	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-0.9928646837764816	[421]	[178]	-5	hSpCas9	negative selection	630379
152347006	152347029	4	-	26472758	K562	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-0.22750383515404726	[318]	[229]	-1	hSpCas9	negative selection	630380
152332596	152332619	4	-	26472758	K562	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	0.18655854070755212	[406]	[390]	1	hSpCas9	negative selection	630381
152326033	152326056	4	-	26472758	K562	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-0.7614818737732374	[244]	[121]	-4	hSpCas9	negative selection	630382
152347047	152347070	4	+	26472758	K562	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.14576358292612124	[421]	[321]	-1	hSpCas9	negative selection	630383
152328288	152328311	4	-	26472758	K562	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-1.6068238383921571	[266]	[73]	-7	hSpCas9	negative selection	630384
152330751	152330774	4	-	26627737	DLD1	viability	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	0.23794316301241913	[307]	[81,145,113]	2	hSpCas9	negative selection	824098
152347047	152347070	4	+	26627737	DLD1	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.22906658455172035	[815]	[327,219,119]	-2	hSpCas9	negative selection	824099
152350085	152350108	4	+	26627737	DLD1	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	0.4772334790839683	[457]	[150,248,199]	5	hSpCas9	negative selection	824100
152352711	152352734	4	-	26627737	DLD1	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.03805923113632326	[1206]	[376,475,322]	0	hSpCas9	negative selection	824101
152382211	152382234	4	-	26627737	DLD1	viability	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.7039974399726882	[436]	[36,81,125]	-6	hSpCas9	negative selection	824102
152411716	152411739	4	+	26627737	DLD1	viability	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.5366512901300634	[349]	[131,201,145]	5	hSpCas9	negative selection	824103
152330751	152330774	4	-	26627737	GBM cells	viability after 5 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.9795241452334013	[181]	[41,56]	-9	hSpCas9	negative selection	906413
152347047	152347070	4	+	26627737	GBM cells	viability after 5 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.7185364785843751	[493]	[191,129]	-8	hSpCas9	negative selection	906414
152350085	152350108	4	+	26627737	GBM cells	viability after 5 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.1168534409726312	[367]	[63,117]	-9	hSpCas9	negative selection	906415
152352711	152352734	4	-	26627737	GBM cells	viability after 5 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.1439802183016492	[750]	[302,425]	-2	hSpCas9	negative selection	906416
152382211	152382234	4	-	26627737	GBM cells	viability after 5 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.7840568296397915	[235]	[53,92]	-8	hSpCas9	negative selection	906417
152411716	152411739	4	+	26627737	GBM cells	viability after 5 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.2553070438091832	[216]	[82,111]	-4	hSpCas9	negative selection	906418
152330751	152330774	4	-	26627737	GBM cells	viability after 13 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-1.4670075832347234	[181]	[27,41]	-9	hSpCas9	negative selection	988728
152347047	152347070	4	+	26627737	GBM cells	viability after 13 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.6156592979440725	[493]	[119,60]	-9	hSpCas9	negative selection	988729
152350085	152350108	4	+	26627737	GBM cells	viability after 13 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.4618424080576742	[367]	[77,67]	-9	hSpCas9	negative selection	988730
152352711	152352734	4	-	26627737	GBM cells	viability after 13 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.05426039261618021	[750]	[510,295]	0	hSpCas9	negative selection	988731
152382211	152382234	4	-	26627737	GBM cells	viability after 13 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.5286256765070497	[235]	[101,77]	-6	hSpCas9	negative selection	988732
152411716	152411739	4	+	26627737	GBM cells	viability after 13 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.20162485139268876	[216]	[108,96]	-2	hSpCas9	negative selection	988733
152330751	152330774	4	-	26627737	GBM cells	viability after 21 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-1.6676881688382061	[181]	[39,22]	-8	hSpCas9	negative selection	1071043
152347047	152347070	4	+	26627737	GBM cells	viability after 21 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-2.7274925439625815	[493]	[39,40]	-9	hSpCas9	negative selection	1071044
152350085	152350108	4	+	26627737	GBM cells	viability after 21 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-2.734302316488845	[367]	[28,30]	-9	hSpCas9	negative selection	1071045
152352711	152352734	4	-	26627737	GBM cells	viability after 21 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.47178236153114583	[750]	[312,276]	-4	hSpCas9	negative selection	1071046
152382211	152382234	4	-	26627737	GBM cells	viability after 21 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.21088505679029934	[235]	[115,105]	-2	hSpCas9	negative selection	1071047
152411716	152411739	4	+	26627737	GBM cells	viability after 21 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.2339394584391426	[216]	[117,83]	-2	hSpCas9	negative selection	1071048
152330751	152330774	4	-	26627737	RPE1	viability after 9 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	1.7577205333443624	[245]	[197,340]	8	hSpCas9	negative selection	1153358
152347047	152347070	4	+	26627737	RPE1	viability after 9 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.5352500884260079	[1721]	[603,1009]	3	hSpCas9	negative selection	1153359
152350085	152350108	4	+	26627737	RPE1	viability after 9 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.6156339400916986	[942]	[155,239]	-4	hSpCas9	negative selection	1153360
152352711	152352734	4	-	26627737	RPE1	viability after 9 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.2674330425022349	[1629]	[402,450]	-2	hSpCas9	negative selection	1153361
152382211	152382234	4	-	26627737	RPE1	viability after 9 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.8518426592882242	[594]	[114,87]	-6	hSpCas9	negative selection	1153362
152411716	152411739	4	+	26627737	RPE1	viability after 9 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	4.271567623719392	[25]	[137,181]	9	hSpCas9	negative selection	1153363
152330751	152330774	4	-	26627737	RPE1	viability after 12 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	1.7336444823957666	[245]	[297,136]	8	hSpCas9	negative selection	1235673
152347047	152347070	4	+	26627737	RPE1	viability after 12 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.36665486298973393	[1721]	[528,667]	2	hSpCas9	negative selection	1235674
152350085	152350108	4	+	26627737	RPE1	viability after 12 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.15881727798710343	[942]	[190,264]	-1	hSpCas9	negative selection	1235675
152352711	152352734	4	-	26627737	RPE1	viability after 12 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.33254923587567276	[1629]	[356,337]	-2	hSpCas9	negative selection	1235676
152382211	152382234	4	-	26627737	RPE1	viability after 12 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-1.0126855624276558	[594]	[86,70]	-6	hSpCas9	negative selection	1235677
152411716	152411739	4	+	26627737	RPE1	viability after 12 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	5.317279212310419	[25]	[244,313]	9	hSpCas9	negative selection	1235678
152330751	152330774	4	-	26627737	RPE1	viability after 15 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	1.5570416855930846	[245]	[189,218]	8	hSpCas9	negative selection	1317988
152347047	152347070	4	+	26627737	RPE1	viability after 15 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.3587925735730464	[1721]	[615,632]	2	hSpCas9	negative selection	1317989
152350085	152350108	4	+	26627737	RPE1	viability after 15 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.005236561883362856	[942]	[333,199]	0	hSpCas9	negative selection	1317990
152352711	152352734	4	-	26627737	RPE1	viability after 15 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.017546387993131463	[1629]	[537,397]	0	hSpCas9	negative selection	1317991
152382211	152382234	4	-	26627737	RPE1	viability after 15 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.4490897718311827	[594]	[106,138]	-3	hSpCas9	negative selection	1317992
152411716	152411739	4	+	26627737	RPE1	viability after 15 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	4.987511137289428	[25]	[214,250]	9	hSpCas9	negative selection	1317993
152330751	152330774	4	-	26627737	RPE1	viability after 18 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	1.809431203364734	[245]	[179,288]	8	hSpCas9	negative selection	1400303
152347047	152347070	4	+	26627737	RPE1	viability after 18 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.4658448622955782	[1721]	[665,615]	3	hSpCas9	negative selection	1400304
152350085	152350108	4	+	26627737	RPE1	viability after 18 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.3145026779452412	[942]	[164,246]	-2	hSpCas9	negative selection	1400305
152352711	152352734	4	-	26627737	RPE1	viability after 18 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.02930116029867169	[1629]	[475,382]	0	hSpCas9	negative selection	1400306
152382211	152382234	4	-	26627737	RPE1	viability after 18 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.635937749894778	[594]	[112,92]	-4	hSpCas9	negative selection	1400307
152411716	152411739	4	+	26627737	RPE1	viability after 18 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	5.2673097720777795	[25]	[145,402]	9	hSpCas9	negative selection	1400308
152330751	152330774	4	-	26627737	HeLa	viability after 8 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.11885247580016067	[270]	[36,163,108]	-1	hSpCas9	negative selection	1482618
152347047	152347070	4	+	26627737	HeLa	viability after 8 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.6375230424595434	[673]	[495,432,448]	5	hSpCas9	negative selection	1482619
152350085	152350108	4	+	26627737	HeLa	viability after 8 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.783144305728502	[625]	[235,112,143]	-7	hSpCas9	negative selection	1482620
152352711	152352734	4	-	26627737	HeLa	viability after 8 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.35322185497386704	[1133]	[477,417,289]	-3	hSpCas9	negative selection	1482621
152382211	152382234	4	-	26627737	HeLa	viability after 8 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.8763279533059978	[194]	[46,47,43]	-7	hSpCas9	negative selection	1482622
152411716	152411739	4	+	26627737	HeLa	viability after 8 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.31537332809707974	[275]	[99,103,86]	-3	hSpCas9	negative selection	1482623
152330751	152330774	4	-	26627737	HeLa	viability after 12 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.2597770783572597	[270]	[69,158,43]	-2	hSpCas9	negative selection	1564933
152347047	152347070	4	+	26627737	HeLa	viability after 12 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.21960578388179686	[673]	[385,246,349]	2	hSpCas9	negative selection	1564934
152350085	152350108	4	+	26627737	HeLa	viability after 12 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.09146000090025896	[625]	[455,144,143]	-1	hSpCas9	negative selection	1564935
152352711	152352734	4	-	26627737	HeLa	viability after 12 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.6319163085598858	[1133]	[488,308,113]	-5	hSpCas9	negative selection	1564936
152382211	152382234	4	-	26627737	HeLa	viability after 12 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.2193343486645003	[194]	[60,107,109]	2	hSpCas9	negative selection	1564937
152411716	152411739	4	+	26627737	HeLa	viability after 12 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.7268514097021944	[275]	[14,98,87]	-6	hSpCas9	negative selection	1564938
152330751	152330774	4	-	26627737	HeLa	viability after 15 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.10035142139593856	[270]	[14,129,169]	-1	hSpCas9	negative selection	1647248
152347047	152347070	4	+	26627737	HeLa	viability after 15 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.12553679655655914	[673]	[209,330,210]	-1	hSpCas9	negative selection	1647249
152350085	152350108	4	+	26627737	HeLa	viability after 15 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.214822813828686	[625]	[296,234,117]	-2	hSpCas9	negative selection	1647250
152352711	152352734	4	-	26627737	HeLa	viability after 15 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.4124335203652485	[1133]	[292,404,342]	-4	hSpCas9	negative selection	1647251
152382211	152382234	4	-	26627737	HeLa	viability after 15 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.7954341421089128	[194]	[3,72,61]	-6	hSpCas9	negative selection	1647252
152411716	152411739	4	+	26627737	HeLa	viability after 15 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.4153741145705504	[275]	[58,146,43]	-4	hSpCas9	negative selection	1647253
152330751	152330774	4	-	26627737	HeLa	viability after 18 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.10453153030984563	[270]	[9,106,169]	-1	hSpCas9	negative selection	1729563
152347047	152347070	4	+	26627737	HeLa	viability after 18 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.11134746261088257	[673]	[144,274,210]	-1	hSpCas9	negative selection	1729564
152350085	152350108	4	+	26627737	HeLa	viability after 18 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.20052622432657602	[625]	[203,193,117]	-2	hSpCas9	negative selection	1729565
152352711	152352734	4	-	26627737	HeLa	viability after 18 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.3609211274187707	[1133]	[206,352,342]	-3	hSpCas9	negative selection	1729566
152382211	152382234	4	-	26627737	HeLa	viability after 18 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.7831716648733102	[194]	[2,60,61]	-6	hSpCas9	negative selection	1729567
152411716	152411739	4	+	26627737	HeLa	viability after 18 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.38542905138809425	[275]	[41,122,43]	-3	hSpCas9	negative selection	1729568
152330751	152330774	4	-	26627737	HCT116	viability after 6 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	0.21390831966936244	[522]	[202,35]	1	hSpCas9	negative selection	1811878
152347047	152347070	4	+	26627737	HCT116	viability after 6 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.4649822244158859	[1510]	[401,286]	2	hSpCas9	negative selection	1811879
152350085	152350108	4	+	26627737	HCT116	viability after 6 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.1403697227690504	[775]	[6,81]	-6	hSpCas9	negative selection	1811880
152352711	152352734	4	-	26627737	HCT116	viability after 6 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.056620469819608	[1444]	[84,291]	0	hSpCas9	negative selection	1811881
152382211	152382234	4	-	26627737	HCT116	viability after 6 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.4410715820981863	[687]	[205,9]	-3	hSpCas9	negative selection	1811882
152411716	152411739	4	+	26627737	HCT116	viability after 6 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	1.0775135944731271	[592]	[23,291]	6	hSpCas9	negative selection	1811883
152330751	152330774	4	-	26627737	HCT116	viability after 8 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	0.08979052514976016	[243]	[76,201,148]	1	hSpCas9	negative selection	1894193
152347047	152347070	4	+	26627737	HCT116	viability after 8 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.4307027843208676	[689]	[240,363,240]	-5	hSpCas9	negative selection	1894194
152350085	152350108	4	+	26627737	HCT116	viability after 8 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.3818998942872184	[470]	[179,285,131]	-4	hSpCas9	negative selection	1894195
152352711	152352734	4	-	26627737	HCT116	viability after 8 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.6861857032474957	[962]	[284,326,375]	-7	hSpCas9	negative selection	1894196
152382211	152382234	4	-	26627737	HCT116	viability after 8 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.134987644329577	[129]	[98,112,24]	1	hSpCas9	negative selection	1894197
152411716	152411739	4	+	26627737	HCT116	viability after 8 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.14372993980417342	[284]	[138,194,92]	-2	hSpCas9	negative selection	1894198
152330751	152330774	4	-	26627737	HCT116	viability after 9 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	0.4150179771812815	[522]	[169,198]	3	hSpCas9	negative selection	1976508
152347047	152347070	4	+	26627737	HCT116	viability after 9 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.5123749051859269	[1510]	[350,228]	-4	hSpCas9	negative selection	1976509
152350085	152350108	4	+	26627737	HCT116	viability after 9 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.7411460475943046	[775]	[109,134]	-5	hSpCas9	negative selection	1976510
152352711	152352734	4	-	26627737	HCT116	viability after 9 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.25890009886961995	[1444]	[354,545]	2	hSpCas9	negative selection	1976511
152382211	152382234	4	-	26627737	HCT116	viability after 9 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.09548912550183977	[687]	[350,73]	0	hSpCas9	negative selection	1976512
152411716	152411739	4	+	26627737	HCT116	viability after 9 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.8853721135813075	[592]	[344,250]	6	hSpCas9	negative selection	1976513
152330751	152330774	4	-	26627737	HCT116	viability after 12 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	0.19080214841332976	[243]	[98,218,126]	2	hSpCas9	negative selection	2058823
152347047	152347070	4	+	26627737	HCT116	viability after 12 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.6299423754622443	[689]	[236,327,139]	-6	hSpCas9	negative selection	2058824
152350085	152350108	4	+	26627737	HCT116	viability after 12 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.4301602759690549	[470]	[172,139,237]	-4	hSpCas9	negative selection	2058825
152352711	152352734	4	-	26627737	HCT116	viability after 12 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.3785767758663101	[962]	[375,306,483]	-4	hSpCas9	negative selection	2058826
152382211	152382234	4	-	26627737	HCT116	viability after 12 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.4682075392167445	[129]	[122,51,104]	4	hSpCas9	negative selection	2058827
152411716	152411739	4	+	26627737	HCT116	viability after 12 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.5562720907959399	[284]	[103,44,154]	-5	hSpCas9	negative selection	2058828
152330751	152330774	4	-	26627737	HCT116	viability after 15 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.22503469015069305	[243]	[114,117,125]	-2	hSpCas9	negative selection	2141138
152347047	152347070	4	+	26627737	HCT116	viability after 15 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.7370583178230721	[689]	[238,370,104]	-6	hSpCas9	negative selection	2141139
152350085	152350108	4	+	26627737	HCT116	viability after 15 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.1726637162177571	[470]	[113,104,139]	-8	hSpCas9	negative selection	2141140
152352711	152352734	4	-	26627737	HCT116	viability after 15 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.6218971673422755	[962]	[338,322,412]	-6	hSpCas9	negative selection	2141141
152382211	152382234	4	-	26627737	HCT116	viability after 15 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.2550939435310624	[129]	[33,70,78]	-3	hSpCas9	negative selection	2141142
152411716	152411739	4	+	26627737	HCT116	viability after 15 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.4404812142059818	[284]	[94,166,96]	-4	hSpCas9	negative selection	2141143
152330751	152330774	4	-	26627737	HCT116	viability after 18 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.08998604517698755	[243]	[75,154,97]	-1	hSpCas9	negative selection	2223453
152347047	152347070	4	+	26627737	HCT116	viability after 18 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.9749943948543651	[689]	[120,224,158]	-7	hSpCas9	negative selection	2223454
152350085	152350108	4	+	26627737	HCT116	viability after 18 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.7700352756072268	[470]	[100,168,127]	-6	hSpCas9	negative selection	2223455
152352711	152352734	4	-	26627737	HCT116	viability after 18 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.3782411944380848	[962]	[426,274,378]	-3	hSpCas9	negative selection	2223456
152382211	152382234	4	-	26627737	HCT116	viability after 18 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-1.0193037629984156	[129]	[51,13,27]	-7	hSpCas9	negative selection	2223457
152411716	152411739	4	+	26627737	HCT116	viability after 18 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.2849783023481033	[284]	[180,95,60]	-3	hSpCas9	negative selection	2223458
152346958	152346981	4	-	24336569	HL60	viability	ACATCTGTCCAGCCACCTACAGG	FBXW7	ENSG00000109670	0.25009575658252337	[626]	[1577]	2	hSpCas9	negative selection	2266213
152346965	152346988	4	+	24336569	HL60	viability	GTGGCTGGACAGATGTAATTCGG	FBXW7	ENSG00000109670	-0.3637685333930074	[1431]	[2354]	-3	hSpCas9	negative selection	2266214
152346983	152347006	4	+	24336569	HL60	viability	TTCGGCGTCGTTGTTGCCCTTGG	FBXW7	ENSG00000109670	0.003821087316073113	[155]	[330]	0	hSpCas9	negative selection	2266215
152346990	152347013	4	+	24336569	HL60	viability	TCGTTGTTGCCCTTGGCCATTGG	FBXW7	ENSG00000109670	0.8841267370924282	[1431]	[5592]	7	hSpCas9	negative selection	2266216
152346999	152347022	4	-	24336569	HL60	viability	TCAGAGCAGCCAATGGCCAAGGG	FBXW7	ENSG00000109670	-0.40006819428073637	[1137]	[1824]	-4	hSpCas9	negative selection	2266217
152347033	152347056	4	+	24336569	HL60	viability	GTTGTTGGTGTTGCTGAACATGG	FBXW7	ENSG00000109670	0.49144717812490946	[560]	[1668]	4	hSpCas9	negative selection	2266218
152347047	152347070	4	+	24336569	HL60	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.81660754812435	[721]	[2690]	6	hSpCas9	negative selection	2266219
152350041	152350064	4	-	24336569	HL60	viability	GCAAAGTCTCAGAATATACAAGG	FBXW7	ENSG00000109670	1.1120569064393324	[565]	[2588]	8	hSpCas9	negative selection	2266220
152350085	152350108	4	+	24336569	HL60	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	0.003617400260871706	[427]	[907]	0	hSpCas9	negative selection	2266221
152350094	152350117	4	-	24336569	HL60	viability	AAAGTTGGACCATGGTTCTGAGG	FBXW7	ENSG00000109670	0.21063729251895597	[605]	[1483]	2	hSpCas9	negative selection	2266222
152346958	152346981	4	-	24336569	KBM7	viability	ACATCTGTCCAGCCACCTACAGG	FBXW7	ENSG00000109670	-0.34066399263237046	[233]	[503]	-3	hSpCas9	negative selection	2333390
152346965	152346988	4	+	24336569	KBM7	viability	GTGGCTGGACAGATGTAATTCGG	FBXW7	ENSG00000109670	-0.21253147440640563	[680]	[1602]	-2	hSpCas9	negative selection	2333391
152346983	152347006	4	+	24336569	KBM7	viability	TTCGGCGTCGTTGTTGCCCTTGG	FBXW7	ENSG00000109670	0.8582292329752028	[359]	[1779]	7	hSpCas9	negative selection	2333392
152346990	152347013	4	+	24336569	KBM7	viability	TCGTTGTTGCCCTTGGCCATTGG	FBXW7	ENSG00000109670	-0.16822694478899236	[1347]	[3271]	-1	hSpCas9	negative selection	2333393
152346999	152347022	4	-	24336569	KBM7	viability	TCAGAGCAGCCAATGGCCAAGGG	FBXW7	ENSG00000109670	-1.835849786264941	[800]	[611]	-8	hSpCas9	negative selection	2333394
152347033	152347056	4	+	24336569	KBM7	viability	GTTGTTGGTGTTGCTGAACATGG	FBXW7	ENSG00000109670	-0.1941181174218895	[314]	[750]	-2	hSpCas9	negative selection	2333395
152347047	152347070	4	+	24336569	KBM7	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-4.0751860346785325	[926]	[149]	-9	hSpCas9	negative selection	2333396
152350041	152350064	4	-	24336569	KBM7	viability	GCAAAGTCTCAGAATATACAAGG	FBXW7	ENSG00000109670	0.5124008713686644	[264]	[1030]	5	hSpCas9	negative selection	2333397
152350085	152350108	4	+	24336569	KBM7	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-4.089242284749691	[492]	[78]	-9	hSpCas9	negative selection	2333398
152350094	152350117	4	-	24336569	KBM7	viability	AAAGTTGGACCATGGTTCTGAGG	FBXW7	ENSG00000109670	-0.25011765685026915	[541]	[1242]	-2	hSpCas9	negative selection	2333399
152382681	152382704	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACTCTTAGATTAGTTAGTTGG	FBXW7	ENSG00000109670	-0.8087864384363201	[118,214]	[19,20]	-4	dCas9-VP64	positive selection	2388953
152382641	152382664	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAGCAGGGCTGTGCTGTAAGG	FBXW7	ENSG00000109670	-0.07733093744495356	[483,475]	[122,74]	0	dCas9-VP64	positive selection	2388954
152382608	152382631	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATTACTGACTTTGTATGAGAGG	FBXW7	ENSG00000109670	-0.2932135270403644	[49,22]	[9,1]	-1	dCas9-VP64	positive selection	2388955
152496085	152496108	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAATTGCTTGAACCCAGGCAG	FBXW7	ENSG00000109670	0.059142044687262585	[6,100]	[1,23]	0	dCas9-VP64	positive selection	2407339
152533045	152533068	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGTGCTACCACGCCTGG	FBXW7	ENSG00000109670	3.748247150670283	[1,20]	[67,2]	9	dCas9-VP64	positive selection	2410129
152535333	152535356	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCTCCTTGGCTGGACTCCGGG	FBXW7	ENSG00000109670	0.02386784591773372	[630,122]	[40,128]	0	dCas9-VP64	positive selection	2416603
152535361	152535384	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTCTCCCTTGGCCAGTCGCCGG	FBXW7	ENSG00000109670	-1.147118285020494	[335,464]	[56,19]	-6	dCas9-VP64	positive selection	2416604
152535315	152535338	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGCTCTAGGAACTCCTCCCGG	FBXW7	ENSG00000109670	-0.5150266002880706	[344,16]	[21,32]	-3	dCas9-VP64	positive selection	2416605
152353018	152353041	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGTTTGAAAGGGGAGAGGGGG	FBXW7	ENSG00000109670	0.20191458749638125	[26,0]	[4,0]	1	dCas9-VP64	positive selection	2449852
152353026	152353049	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTCTTGAAAGTTTGAAAGGGG	FBXW7	ENSG00000109670	4.1401248895098615	[23,18]	[139,24]	9	dCas9-VP64	positive selection	2449853
152353155	152353178	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATACGGTCCCCCTGAACTGAGG	FBXW7	ENSG00000109670	-0.49803625222840414	[142,73]	[22,8]	-2	dCas9-VP64	positive selection	2449854
152535117	152535140	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAAAAGAGGAGGTAAGCGGGG	FBXW7	ENSG00000109670	0.20440390421537774	[43,97]	[4,30]	1	dCas9-VP64	positive selection	2461667
152535172	152535195	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGTCCAGGGCCACTTCTCCCGG	FBXW7	ENSG00000109670	-0.6377003579177086	[149,43]	[13,11]	-3	dCas9-VP64	positive selection	2461668
152535142	152535165	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCTGGGTCTTTTCAGGCTGCGG	FBXW7	ENSG00000109670	-0.12768266426653718	[40,114]	[5,25]	0	dCas9-VP64	positive selection	2461669
152382681	152382704	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACTCTTAGATTAGTTAGTTGG	FBXW7	ENSG00000109670	-0.2907936920729288	[335,200]	[48,92]	-3	dCas9-VP64	positive selection	2484208
152382641	152382664	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAGCAGGGCTGTGCTGTAAGG	FBXW7	ENSG00000109670	-1.3268106928519248	[276,33]	[34,5]	-9	dCas9-VP64	positive selection	2484209
152382608	152382631	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATTACTGACTTTGTATGAGAGG	FBXW7	ENSG00000109670	-0.3496089064116896	[227,77]	[56,22]	-4	dCas9-VP64	positive selection	2484210
152496085	152496108	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAATTGCTTGAACCCAGGCAG	FBXW7	ENSG00000109670	0.5790361197083687	[35,47]	[19,19]	4	dCas9-VP64	positive selection	2502594
152533045	152533068	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGTGCTACCACGCCTGG	FBXW7	ENSG00000109670	-0.05566307319411967	[8,287]	[6,81]	0	dCas9-VP64	positive selection	2505384
152535333	152535356	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCTCCTTGGCTGGACTCCGGG	FBXW7	ENSG00000109670	-0.4395561519060047	[158,116]	[36,28]	-4	dCas9-VP64	positive selection	2511858
152535361	152535384	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTCTCCCTTGGCCAGTCGCCGG	FBXW7	ENSG00000109670	0.02916152369542968	[169,217]	[67,60]	0	dCas9-VP64	positive selection	2511859
152535315	152535338	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGCTCTAGGAACTCCTCCCGG	FBXW7	ENSG00000109670	4.724562798275531	[62,145]	[1826,32]	9	dCas9-VP64	positive selection	2511860
152353018	152353041	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGTTTGAAAGGGGAGAGGGGG	FBXW7	ENSG00000109670	-0.5076462905357726	[32,155]	[19,21]	-5	dCas9-VP64	positive selection	2545107
152353026	152353049	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTCTTGAAAGTTTGAAAGGGG	FBXW7	ENSG00000109670	1.6716352761606308	[179,343]	[380,168]	8	dCas9-VP64	positive selection	2545108
152353155	152353178	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATACGGTCCCCCTGAACTGAGG	FBXW7	ENSG00000109670	-0.01427096675013706	[241,108]	[87,27]	0	dCas9-VP64	positive selection	2545109
152535117	152535140	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAAAAGAGGAGGTAAGCGGGG	FBXW7	ENSG00000109670	-0.6296517132765136	[98,116]	[18,25]	-6	dCas9-VP64	positive selection	2556922
152535172	152535195	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGTCCAGGGCCACTTCTCCCGG	FBXW7	ENSG00000109670	0.1898137867123033	[70,75]	[22,29]	1	dCas9-VP64	positive selection	2556923
152535142	152535165	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCTGGGTCTTTTCAGGCTGCGG	FBXW7	ENSG00000109670	1.136924587520225	[191,64]	[129,58]	7	dCas9-VP64	positive selection	2556924
152350085	152350108	4	+	27260157	DLD1	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	0.687382092308323	[]	[]	8	hSpCas9	negative selection	2574837
152352925	152352948	4	+	27260157	DLD1	viability	ATTATATGGTGATCCGCTCCAGG	FBXW7	ENSG00000109670	-0.585108467517326	[]	[]	-5	hSpCas9	negative selection	2576436
152350094	152350117	4	-	27260157	DLD1	viability	AAAGTTGGACCATGGTTCTGAGG	FBXW7	ENSG00000109670	-0.0633364751044226	[]	[]	0	hSpCas9	negative selection	2579410
152411526	152411549	4	-	27260157	DLD1	viability	TCGGTAGATGAGGACTCCTCAGG	FBXW7	ENSG00000109670	0.0599848382764628	[]	[]	3	hSpCas9	negative selection	2579557
152352808	152352831	4	-	27260157	DLD1	viability	GTTCAGTCAAGGCTTTGACAGGG	FBXW7	ENSG00000109670	-0.369302101014082	[]	[]	-3	hSpCas9	negative selection	2581697
152346990	152347013	4	+	27260157	DLD1	viability	TCGTTGTTGCCCTTGGCCATTGG	FBXW7	ENSG00000109670	-0.489234901288207	[]	[]	-4	hSpCas9	negative selection	2584217
152347047	152347070	4	+	27260157	DLD1	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.255250213616061	[]	[]	-2	hSpCas9	negative selection	2587037
152346965	152346988	4	+	27260157	DLD1	viability	GTGGCTGGACAGATGTAATTCGG	FBXW7	ENSG00000109670	1.19290989270219	[]	[]	9	hSpCas9	negative selection	2587225
152411601	152411624	4	-	27260157	DLD1	viability	GGAGTAGAACCTAGACCTGGAGG	FBXW7	ENSG00000109670	0.164433467104678	[]	[]	3	hSpCas9	negative selection	2605540
152350041	152350064	4	-	27260157	DLD1	viability	GCAAAGTCTCAGAATATACAAGG	FBXW7	ENSG00000109670	-0.382049254962764	[]	[]	-3	hSpCas9	negative selection	2607541
152411345	152411368	4	+	27260157	DLD1	viability	GGGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.31667720598087	[]	[]	4	hSpCas9	negative selection	2614122
152346999	152347022	4	-	27260157	DLD1	viability	TCAGAGCAGCCAATGGCCAAGGG	FBXW7	ENSG00000109670	0.301747395995977	[]	[]	4	hSpCas9	negative selection	2615623
152347033	152347056	4	+	27260157	DLD1	viability	GTTGTTGGTGTTGCTGAACATGG	FBXW7	ENSG00000109670	0.13640167176806	[]	[]	3	hSpCas9	negative selection	2620167
152352938	152352961	4	-	27260157	DLD1	viability	TTCTTACGGGTTCCCTGGAGCGG	FBXW7	ENSG00000109670	0.4853206512639	[]	[]	8	hSpCas9	negative selection	2620660
152411329	152411352	4	+	27260157	DLD1	viability	AGGAGAGTTGGTGAACGGGCAGG	FBXW7	ENSG00000109670	1.10927526178653	[]	[]	9	hSpCas9	negative selection	2621202
152352871	152352894	4	-	27260157	DLD1	viability	CTGCACCATTCTGTGTTCAAGGG	FBXW7	ENSG00000109670	0.277426809013907	[]	[]	4	hSpCas9	negative selection	2640943
152382211	152382234	4	-	27260157	DLD1	viability	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.266645084716673	[]	[]	4	hSpCas9	negative selection	2642355
152352951	152352974	4	-	27260157	DLD1	viability	TCAGTGCGTTGTGTTCTTACGGG	FBXW7	ENSG00000109670	-0.704178703174523	[]	[]	-5	hSpCas9	negative selection	2643562
152346958	152346981	4	-	27260157	DLD1	viability	ACATCTGTCCAGCCACCTACAGG	FBXW7	ENSG00000109670	-0.510197300811764	[]	[]	-4	hSpCas9	negative selection	2644219
152346983	152347006	4	+	27260157	DLD1	viability	TTCGGCGTCGTTGTTGCCCTTGG	FBXW7	ENSG00000109670	-0.975999907536738	[]	[]	-7	hSpCas9	negative selection	2647311
152350085	152350108	4	+	27260157	HT1080	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	0.0948621106701096	[]	[]	1	hSpCas9	negative selection	2650967
152352925	152352948	4	+	27260157	HT1080	viability	ATTATATGGTGATCCGCTCCAGG	FBXW7	ENSG00000109670	-0.194893738222725	[]	[]	0	hSpCas9	negative selection	2652566
152350094	152350117	4	-	27260157	HT1080	viability	AAAGTTGGACCATGGTTCTGAGG	FBXW7	ENSG00000109670	-0.633867640004963	[]	[]	-8	hSpCas9	negative selection	2655540
152411526	152411549	4	-	27260157	HT1080	viability	TCGGTAGATGAGGACTCCTCAGG	FBXW7	ENSG00000109670	-0.242121692648032	[]	[]	0	hSpCas9	negative selection	2655687
152352808	152352831	4	-	27260157	HT1080	viability	GTTCAGTCAAGGCTTTGACAGGG	FBXW7	ENSG00000109670	0.0680184607874677	[]	[]	0	hSpCas9	negative selection	2657827
152346990	152347013	4	+	27260157	HT1080	viability	TCGTTGTTGCCCTTGGCCATTGG	FBXW7	ENSG00000109670	-1.04422892037397	[]	[]	-8	hSpCas9	negative selection	2660347
152347047	152347070	4	+	27260157	HT1080	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.867849502948462	[]	[]	-8	hSpCas9	negative selection	2663167
152346965	152346988	4	+	27260157	HT1080	viability	GTGGCTGGACAGATGTAATTCGG	FBXW7	ENSG00000109670	-0.679890559468096	[]	[]	-8	hSpCas9	negative selection	2663355
152411601	152411624	4	-	27260157	HT1080	viability	GGAGTAGAACCTAGACCTGGAGG	FBXW7	ENSG00000109670	0.155592803847018	[]	[]	1	hSpCas9	negative selection	2681670
152350041	152350064	4	-	27260157	HT1080	viability	GCAAAGTCTCAGAATATACAAGG	FBXW7	ENSG00000109670	-0.265432587876461	[]	[]	0	hSpCas9	negative selection	2683671
152411345	152411368	4	+	27260157	HT1080	viability	GGGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	-0.568401608747108	[]	[]	-7	hSpCas9	negative selection	2690252
152346999	152347022	4	-	27260157	HT1080	viability	TCAGAGCAGCCAATGGCCAAGGG	FBXW7	ENSG00000109670	0.167736472124381	[]	[]	1	hSpCas9	negative selection	2691753
152347033	152347056	4	+	27260157	HT1080	viability	GTTGTTGGTGTTGCTGAACATGG	FBXW7	ENSG00000109670	-1.36312012593798	[]	[]	-9	hSpCas9	negative selection	2696297
152352938	152352961	4	-	27260157	HT1080	viability	TTCTTACGGGTTCCCTGGAGCGG	FBXW7	ENSG00000109670	-0.759014753811254	[]	[]	-8	hSpCas9	negative selection	2696790
152411329	152411352	4	+	27260157	HT1080	viability	AGGAGAGTTGGTGAACGGGCAGG	FBXW7	ENSG00000109670	-0.0173229671877216	[]	[]	0	hSpCas9	negative selection	2697332
152352871	152352894	4	-	27260157	HT1080	viability	CTGCACCATTCTGTGTTCAAGGG	FBXW7	ENSG00000109670	1.22619053253582	[]	[]	8	hSpCas9	negative selection	2717073
152382211	152382234	4	-	27260157	HT1080	viability	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.748236611204379	[]	[]	-8	hSpCas9	negative selection	2718485
152352951	152352974	4	-	27260157	HT1080	viability	TCAGTGCGTTGTGTTCTTACGGG	FBXW7	ENSG00000109670	0.111030392762391	[]	[]	1	hSpCas9	negative selection	2719692
152346958	152346981	4	-	27260157	HT1080	viability	ACATCTGTCCAGCCACCTACAGG	FBXW7	ENSG00000109670	0.287413198129293	[]	[]	2	hSpCas9	negative selection	2720349
152346983	152347006	4	+	27260157	HT1080	viability	TTCGGCGTCGTTGTTGCCCTTGG	FBXW7	ENSG00000109670	-0.0556680988650366	[]	[]	0	hSpCas9	negative selection	2723441
152350085	152350108	4	+	27260157	MKN45	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.513794569803393	[]	[]	-6	hSpCas9	negative selection	2727097
152352925	152352948	4	+	27260157	MKN45	viability	ATTATATGGTGATCCGCTCCAGG	FBXW7	ENSG00000109670	0.333640036652944	[]	[]	6	hSpCas9	negative selection	2728696
152350094	152350117	4	-	27260157	MKN45	viability	AAAGTTGGACCATGGTTCTGAGG	FBXW7	ENSG00000109670	-0.474323854030966	[]	[]	-6	hSpCas9	negative selection	2731670
152411526	152411549	4	-	27260157	MKN45	viability	TCGGTAGATGAGGACTCCTCAGG	FBXW7	ENSG00000109670	-0.438900400852732	[]	[]	-6	hSpCas9	negative selection	2731817
152352808	152352831	4	-	27260157	MKN45	viability	GTTCAGTCAAGGCTTTGACAGGG	FBXW7	ENSG00000109670	-0.104200379082643	[]	[]	0	hSpCas9	negative selection	2733957
152346990	152347013	4	+	27260157	MKN45	viability	TCGTTGTTGCCCTTGGCCATTGG	FBXW7	ENSG00000109670	-0.666666801759524	[]	[]	-7	hSpCas9	negative selection	2736477
152347047	152347070	4	+	27260157	MKN45	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.94106428001506	[]	[]	-9	hSpCas9	negative selection	2739297
152346965	152346988	4	+	27260157	MKN45	viability	GTGGCTGGACAGATGTAATTCGG	FBXW7	ENSG00000109670	-0.979995267641532	[]	[]	-7	hSpCas9	negative selection	2739485
152411601	152411624	4	-	27260157	MKN45	viability	GGAGTAGAACCTAGACCTGGAGG	FBXW7	ENSG00000109670	-0.343935726979139	[]	[]	-1	hSpCas9	negative selection	2757800
152350041	152350064	4	-	27260157	MKN45	viability	GCAAAGTCTCAGAATATACAAGG	FBXW7	ENSG00000109670	-0.107999664651801	[]	[]	0	hSpCas9	negative selection	2759801
152411345	152411368	4	+	27260157	MKN45	viability	GGGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.0795275705437111	[]	[]	0	hSpCas9	negative selection	2766382
152346999	152347022	4	-	27260157	MKN45	viability	TCAGAGCAGCCAATGGCCAAGGG	FBXW7	ENSG00000109670	-0.0186985416078348	[]	[]	0	hSpCas9	negative selection	2767883
152347033	152347056	4	+	27260157	MKN45	viability	GTTGTTGGTGTTGCTGAACATGG	FBXW7	ENSG00000109670	-0.13838102408146	[]	[]	0	hSpCas9	negative selection	2772427
152352938	152352961	4	-	27260157	MKN45	viability	TTCTTACGGGTTCCCTGGAGCGG	FBXW7	ENSG00000109670	-0.416759032375987	[]	[]	-6	hSpCas9	negative selection	2772920
152411329	152411352	4	+	27260157	MKN45	viability	AGGAGAGTTGGTGAACGGGCAGG	FBXW7	ENSG00000109670	0.162537855911684	[]	[]	5	hSpCas9	negative selection	2773462
152352871	152352894	4	-	27260157	MKN45	viability	CTGCACCATTCTGTGTTCAAGGG	FBXW7	ENSG00000109670	-0.436688611893358	[]	[]	-6	hSpCas9	negative selection	2793203
152382211	152382234	4	-	27260157	MKN45	viability	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.202152778117472	[]	[]	0	hSpCas9	negative selection	2794615
152352951	152352974	4	-	27260157	MKN45	viability	TCAGTGCGTTGTGTTCTTACGGG	FBXW7	ENSG00000109670	-1.99763625089199	[]	[]	-9	hSpCas9	negative selection	2795822
152346958	152346981	4	-	27260157	MKN45	viability	ACATCTGTCCAGCCACCTACAGG	FBXW7	ENSG00000109670	0.189113962344745	[]	[]	5	hSpCas9	negative selection	2796479
152346983	152347006	4	+	27260157	MKN45	viability	TTCGGCGTCGTTGTTGCCCTTGG	FBXW7	ENSG00000109670	-0.433652888029755	[]	[]	-6	hSpCas9	negative selection	2799571
152350085	152350108	4	+	27260157	RKO	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.35411272330038	[]	[]	-8	hSpCas9	negative selection	2803227
152352925	152352948	4	+	27260157	RKO	viability	ATTATATGGTGATCCGCTCCAGG	FBXW7	ENSG00000109670	-0.023144557435328	[]	[]	0	hSpCas9	negative selection	2804826
152350094	152350117	4	-	27260157	RKO	viability	AAAGTTGGACCATGGTTCTGAGG	FBXW7	ENSG00000109670	-1.75772199509051	[]	[]	-9	hSpCas9	negative selection	2807800
152411526	152411549	4	-	27260157	RKO	viability	TCGGTAGATGAGGACTCCTCAGG	FBXW7	ENSG00000109670	0.00482386243527439	[]	[]	0	hSpCas9	negative selection	2807947
152352808	152352831	4	-	27260157	RKO	viability	GTTCAGTCAAGGCTTTGACAGGG	FBXW7	ENSG00000109670	-1.08361422738988	[]	[]	-8	hSpCas9	negative selection	2810087
152346990	152347013	4	+	27260157	RKO	viability	TCGTTGTTGCCCTTGGCCATTGG	FBXW7	ENSG00000109670	-1.51354864674138	[]	[]	-8	hSpCas9	negative selection	2812607
152347047	152347070	4	+	27260157	RKO	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.57473105214555	[]	[]	-9	hSpCas9	negative selection	2815427
152346965	152346988	4	+	27260157	RKO	viability	GTGGCTGGACAGATGTAATTCGG	FBXW7	ENSG00000109670	-1.68686793096011	[]	[]	-9	hSpCas9	negative selection	2815615
152411601	152411624	4	-	27260157	RKO	viability	GGAGTAGAACCTAGACCTGGAGG	FBXW7	ENSG00000109670	-0.576194143871022	[]	[]	-7	hSpCas9	negative selection	2833930
152350041	152350064	4	-	27260157	RKO	viability	GCAAAGTCTCAGAATATACAAGG	FBXW7	ENSG00000109670	-1.78931615069886	[]	[]	-9	hSpCas9	negative selection	2835931
152411345	152411368	4	+	27260157	RKO	viability	GGGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	-0.982213333566254	[]	[]	-8	hSpCas9	negative selection	2842512
152346999	152347022	4	-	27260157	RKO	viability	TCAGAGCAGCCAATGGCCAAGGG	FBXW7	ENSG00000109670	-1.14528987420159	[]	[]	-8	hSpCas9	negative selection	2844013
152347033	152347056	4	+	27260157	RKO	viability	GTTGTTGGTGTTGCTGAACATGG	FBXW7	ENSG00000109670	-1.79547423053478	[]	[]	-9	hSpCas9	negative selection	2848557
152352938	152352961	4	-	27260157	RKO	viability	TTCTTACGGGTTCCCTGGAGCGG	FBXW7	ENSG00000109670	-0.417567581320087	[]	[]	-6	hSpCas9	negative selection	2849050
152411329	152411352	4	+	27260157	RKO	viability	AGGAGAGTTGGTGAACGGGCAGG	FBXW7	ENSG00000109670	-0.186847496176737	[]	[]	-1	hSpCas9	negative selection	2849592
152352871	152352894	4	-	27260157	RKO	viability	CTGCACCATTCTGTGTTCAAGGG	FBXW7	ENSG00000109670	0.054081584271332	[]	[]	0	hSpCas9	negative selection	2869333
152382211	152382234	4	-	27260157	RKO	viability	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.182906435723973	[]	[]	1	hSpCas9	negative selection	2870745
152352951	152352974	4	-	27260157	RKO	viability	TCAGTGCGTTGTGTTCTTACGGG	FBXW7	ENSG00000109670	-0.34977492542509	[]	[]	-6	hSpCas9	negative selection	2871952
152346958	152346981	4	-	27260157	RKO	viability	ACATCTGTCCAGCCACCTACAGG	FBXW7	ENSG00000109670	-1.39427010805416	[]	[]	-8	hSpCas9	negative selection	2872609
152346983	152347006	4	+	27260157	RKO	viability	TTCGGCGTCGTTGTTGCCCTTGG	FBXW7	ENSG00000109670	-1.35349035395222	[]	[]	-8	hSpCas9	negative selection	2875701
152350085	152350108	4	+	27260157	SF268	viability	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	0.73946674997182	[]	[]	8	hSpCas9	negative selection	2879357
152352925	152352948	4	+	27260157	SF268	viability	ATTATATGGTGATCCGCTCCAGG	FBXW7	ENSG00000109670	-0.22839427442542	[]	[]	-2	hSpCas9	negative selection	2880956
152350094	152350117	4	-	27260157	SF268	viability	AAAGTTGGACCATGGTTCTGAGG	FBXW7	ENSG00000109670	-0.0159928862906366	[]	[]	0	hSpCas9	negative selection	2883930
152411526	152411549	4	-	27260157	SF268	viability	TCGGTAGATGAGGACTCCTCAGG	FBXW7	ENSG00000109670	0.322006324843197	[]	[]	4	hSpCas9	negative selection	2884077
152352808	152352831	4	-	27260157	SF268	viability	GTTCAGTCAAGGCTTTGACAGGG	FBXW7	ENSG00000109670	0.0963724066105302	[]	[]	0	hSpCas9	negative selection	2886217
152346990	152347013	4	+	27260157	SF268	viability	TCGTTGTTGCCCTTGGCCATTGG	FBXW7	ENSG00000109670	-0.364485665227278	[]	[]	-3	hSpCas9	negative selection	2888737
152347047	152347070	4	+	27260157	SF268	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.483703925350618	[]	[]	7	hSpCas9	negative selection	2891557
152346965	152346988	4	+	27260157	SF268	viability	GTGGCTGGACAGATGTAATTCGG	FBXW7	ENSG00000109670	1.05627697077799	[]	[]	9	hSpCas9	negative selection	2891745
152411601	152411624	4	-	27260157	SF268	viability	GGAGTAGAACCTAGACCTGGAGG	FBXW7	ENSG00000109670	0.396805723231554	[]	[]	4	hSpCas9	negative selection	2910060
152350041	152350064	4	-	27260157	SF268	viability	GCAAAGTCTCAGAATATACAAGG	FBXW7	ENSG00000109670	0.713459892253005	[]	[]	8	hSpCas9	negative selection	2912061
152411345	152411368	4	+	27260157	SF268	viability	GGGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.491901888748314	[]	[]	7	hSpCas9	negative selection	2918642
152346999	152347022	4	-	27260157	SF268	viability	TCAGAGCAGCCAATGGCCAAGGG	FBXW7	ENSG00000109670	1.24144837228223	[]	[]	9	hSpCas9	negative selection	2920143
152347033	152347056	4	+	27260157	SF268	viability	GTTGTTGGTGTTGCTGAACATGG	FBXW7	ENSG00000109670	-0.289008037876595	[]	[]	-2	hSpCas9	negative selection	2924687
152352938	152352961	4	-	27260157	SF268	viability	TTCTTACGGGTTCCCTGGAGCGG	FBXW7	ENSG00000109670	-0.663995571768915	[]	[]	-5	hSpCas9	negative selection	2925180
152411329	152411352	4	+	27260157	SF268	viability	AGGAGAGTTGGTGAACGGGCAGG	FBXW7	ENSG00000109670	0.474112520978457	[]	[]	7	hSpCas9	negative selection	2925722
152352871	152352894	4	-	27260157	SF268	viability	CTGCACCATTCTGTGTTCAAGGG	FBXW7	ENSG00000109670	0.516076217629499	[]	[]	8	hSpCas9	negative selection	2945463
152382211	152382234	4	-	27260157	SF268	viability	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.238106499998366	[]	[]	3	hSpCas9	negative selection	2946875
152352951	152352974	4	-	27260157	SF268	viability	TCAGTGCGTTGTGTTCTTACGGG	FBXW7	ENSG00000109670	-0.293384946992365	[]	[]	-2	hSpCas9	negative selection	2948082
152346958	152346981	4	-	27260157	SF268	viability	ACATCTGTCCAGCCACCTACAGG	FBXW7	ENSG00000109670	1.37336610597301	[]	[]	9	hSpCas9	negative selection	2948739
152346983	152347006	4	+	27260157	SF268	viability	TTCGGCGTCGTTGTTGCCCTTGG	FBXW7	ENSG00000109670	-0.386198850619261	[]	[]	-3	hSpCas9	negative selection	2951831
152411717	152411740	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.32473543669445515	[3,3]	[3,3]	7	hSpCas9	positive selection	2988297
152411742	152411765	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAACTGGAGGCTCTCTGAGAGG	FBXW7	ENSG00000109670	-0.1539196997472762	[4,4]	[3,2]	-2	hSpCas9	positive selection	2988298
152411653	152411676	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAACTCAGACAACAAGAGGAGG	FBXW7	ENSG00000109670	0.8809712569385892	[3,3]	[5,7]	9	hSpCas9	positive selection	2988299
152411695	152411718	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAGAACAGATGAATCGTGTGG	FBXW7	ENSG00000109670	0.4594216436081713	[3,3]	[4,4]	8	hSpCas9	positive selection	2988300
152411717	152411740	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.12394195858292817	[3,3]	[4,0]	-2	hSpCas9	positive selection	3056155
152411742	152411765	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAACTGGAGGCTCTCTGAGAGG	FBXW7	ENSG00000109670	0.11966612056028447	[4,4]	[4,2]	2	hSpCas9	positive selection	3056156
152411653	152411676	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAACTCAGACAACAAGAGGAGG	FBXW7	ENSG00000109670	-0.16496031467951552	[3,3]	[4,0]	-2	hSpCas9	positive selection	3056157
152411695	152411718	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAGAACAGATGAATCGTGTGG	FBXW7	ENSG00000109670	0.9169958554933262	[3,3]	[5,5]	9	hSpCas9	positive selection	3056158
152330759	152330782		-	24336571	A375	resistance to PLX after 7 days	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.2725011383608607	[13,16]	[14,10]	-7	hSpCas9	positive selection	3114379
152330731	152330754		-	24336571	A375	resistance to PLX after 7 days	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.14415291891907944	[13,12]	[10,12]	-4	hSpCas9	positive selection	3114380
152329736	152329759		-	24336571	A375	resistance to PLX after 7 days	ATCACATGCTTACAGTTTTGTGG	FBXW7	ENSG00000109670	0.04197743548574939	[67,65]	[67,68]	1	hSpCas9	positive selection	3114381
152329710	152329733		+	24336571	A375	resistance to PLX after 7 days	CATCAGAACCACTAACTATTCGG	FBXW7	ENSG00000109670	0.02825115622076857	[32,29]	[28,35]	1	hSpCas9	positive selection	3114382
152330784	152330807		+	24336571	A375	resistance to PLX after 7 days	CTGATGTATGCACTTTTCCATGG	FBXW7	ENSG00000109670	-0.20509100074126274	[40,49]	[38,38]	-6	hSpCas9	positive selection	3114383
152329775	152329798		-	24336571	A375	resistance to PLX after 7 days	TCTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.27614854722282145	[7,6]	[5,4]	-7	hSpCas9	positive selection	3114384
152330759	152330782		-	24336571	A375	resistance to PLX after 14 days	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.850305781200107	[24,15]	[4,4]	-8	hSpCas9	positive selection	3172172
152330731	152330754		-	24336571	A375	resistance to PLX after 14 days	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.4525376501048412	[14,14]	[4,4]	-5	hSpCas9	positive selection	3172173
152329736	152329759		-	24336571	A375	resistance to PLX after 14 days	ATCACATGCTTACAGTTTTGTGG	FBXW7	ENSG00000109670	-0.29604290983935444	[70,72]	[23,29]	-3	hSpCas9	positive selection	3172174
152329710	152329733		+	24336571	A375	resistance to PLX after 14 days	CATCAGAACCACTAACTATTCGG	FBXW7	ENSG00000109670	-0.649203095058267	[31,38]	[10,8]	-7	hSpCas9	positive selection	3172175
152330784	152330807		+	24336571	A375	resistance to PLX after 14 days	CTGATGTATGCACTTTTCCATGG	FBXW7	ENSG00000109670	-0.041370068543181704	[31,46]	[20,13]	0	hSpCas9	positive selection	3172176
152329775	152329798		-	24336571	A375	resistance to PLX after 14 days	TCTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.03114109170888324	[6,2]	[1,1]	0	hSpCas9	positive selection	3172177
152330759	152330782		-	24336571	A375	viability after 7 days	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-1.0136585318359739	[33]	[13,16]	-9	hSpCas9	negative selection	3229965
152330731	152330754		-	24336571	A375	viability after 7 days	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.47227915203612536	[19]	[13,12]	-6	hSpCas9	negative selection	3229966
152329736	152329759		-	24336571	A375	viability after 7 days	ATCACATGCTTACAGTTTTGTGG	FBXW7	ENSG00000109670	0.3786942844149539	[53]	[67,65]	6	hSpCas9	negative selection	3229967
152329710	152329733		+	24336571	A375	viability after 7 days	CATCAGAACCACTAACTATTCGG	FBXW7	ENSG00000109670	-0.5774516165399766	[49]	[32,29]	-7	hSpCas9	negative selection	3229968
152330784	152330807		+	24336571	A375	viability after 7 days	CTGATGTATGCACTTTTCCATGG	FBXW7	ENSG00000109670	-0.07833967084959492	[49]	[40,49]	-1	hSpCas9	negative selection	3229969
152329775	152329798		-	24336571	A375	viability after 7 days	TCTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	0.07875902609409047	[6]	[7,6]	1	hSpCas9	negative selection	3229970
152330759	152330782		-	24336571	A375	viability after 14 days	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.6349836579834265	[33]	[24,15]	-6	hSpCas9	negative selection	3287758
152330731	152330754		-	24336571	A375	viability after 14 days	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.2973868786340572	[19]	[14,14]	-4	hSpCas9	negative selection	3287759
152329736	152329759		-	24336571	A375	viability after 14 days	ATCACATGCTTACAGTTTTGTGG	FBXW7	ENSG00000109670	0.49231251384010055	[53]	[70,72]	6	hSpCas9	negative selection	3287760
152329710	152329733		+	24336571	A375	viability after 14 days	CATCAGAACCACTAACTATTCGG	FBXW7	ENSG00000109670	-0.40393403289601615	[49]	[31,38]	-5	hSpCas9	negative selection	3287761
152330784	152330807		+	24336571	A375	viability after 14 days	CTGATGTATGCACTTTTCCATGG	FBXW7	ENSG00000109670	-0.2493453311803404	[49]	[31,46]	-3	hSpCas9	negative selection	3287762
152329775	152329798		-	24336571	A375	viability after 14 days	TCTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.3118069711529169	[6]	[6,2]	-4	hSpCas9	negative selection	3287763
152382184	152382207	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	1.3983700929010185	[63,51]	[0,0]	6	hSpCas9	positive selection	3349789
152352711	152352734	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-1.182226312671466	[374,318]	[0,0]	-7	hSpCas9	positive selection	3349790
152352699	152352722	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	-1.389308967007499	[365,435]	[0,0]	-8	hSpCas9	positive selection	3349791
152382296	152382319	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-1.1263780810282171	[333,333]	[0,0]	-7	hSpCas9	positive selection	3369001
152330759	152330782	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.9075807152298527	[286,286]	[0,0]	-6	hSpCas9	positive selection	3369002
152330731	152330754	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	3.935398116558473	[9,9]	[0,0]	9	hSpCas9	positive selection	3369003
152411716	152411739	4	+	26780180	HT29	viability (Avana library 4 designs)	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.549664801344681	[]	[]	-7	hSpCas9	negative selection	3425200
152411742	152411765	4	-	26780180	HT29	viability (Avana library 4 designs)	CGAACTGGAGGCTCTCTGAGAGG	FBXW7	ENSG00000109670	0.140893987850205	[]	[]	0	hSpCas9	negative selection	3425201
152411653	152411676	4	-	26780180	HT29	viability (Avana library 4 designs)	GCAACTCAGACAACAAGAGGAGG	FBXW7	ENSG00000109670	-0.397620344134902	[]	[]	-6	hSpCas9	negative selection	3425202
152411695	152411718	4	-	26780180	HT29	viability (Avana library 4 designs)	TGAAGAACAGATGAATCGTGTGG	FBXW7	ENSG00000109670	0.449021191652753	[]	[]	1	hSpCas9	negative selection	3425203
152411653	152411676	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAACTCAGACAACAAGAGGAGG	FBXW7	ENSG00000109670	-0.488275228894494	[]	[]	0	hSpCas9	negative selection	3507212
152411716	152411739	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	3.09590380863488	[]	[]	5	hSpCas9	negative selection	3507213
152411695	152411718	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGAACAGATGAATCGTGTGG	FBXW7	ENSG00000109670	1.80087024315295	[]	[]	2	hSpCas9	negative selection	3507214
152411742	152411765	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAACTGGAGGCTCTCTGAGAGG	FBXW7	ENSG00000109670	5.03328443976154	[]	[]	8	hSpCas9	negative selection	3507215
152411656	152411679	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	-14.5410243123321	[]	[]	-9	hSpCas9	negative selection	3507216
152411686	152411709	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAATCGTGTGGTAGAGGAGG	FBXW7	ENSG00000109670	2.76075135418371	[]	[]	4	hSpCas9	negative selection	3507217
152411653	152411676	4	-	26780180	A375	viability (Avana lentiGuide)	GCAACTCAGACAACAAGAGGAGG	FBXW7	ENSG00000109670	-0.356345275502515	[]	[]	0	hSpCas9	negative selection	3615871
152411716	152411739	4	+	26780180	A375	viability (Avana lentiGuide)	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	3.46821802527373	[]	[]	3	hSpCas9	negative selection	3615872
152411695	152411718	4	-	26780180	A375	viability (Avana lentiGuide)	TGAAGAACAGATGAATCGTGTGG	FBXW7	ENSG00000109670	-2.47516603657285	[]	[]	-4	hSpCas9	negative selection	3615873
152411742	152411765	4	-	26780180	A375	viability (Avana lentiGuide)	CGAACTGGAGGCTCTCTGAGAGG	FBXW7	ENSG00000109670	-0.0522126368186996	[]	[]	0	hSpCas9	negative selection	3615874
152411656	152411679	4	-	26780180	A375	viability (Avana lentiGuide)	ACAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	6.53719114728167	[]	[]	5	hSpCas9	negative selection	3615875
152411686	152411709	4	-	26780180	A375	viability (Avana lentiGuide)	GATGAATCGTGTGGTAGAGGAGG	FBXW7	ENSG00000109670	-1.72768068255056	[]	[]	-3	hSpCas9	negative selection	3615876
152411653	152411676	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAACTCAGACAACAAGAGGAGG	FBXW7	ENSG00000109670	-0.32137949348872064	[4]	[4,2]	-5	hSpCas9	positive selection	3724530
152411716	152411739	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.0965856439035723	[4]	[5,5]	2	hSpCas9	positive selection	3724531
152411695	152411718	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGAACAGATGAATCGTGTGG	FBXW7	ENSG00000109670	-0.11336713719252262	[5]	[4,4]	-2	hSpCas9	positive selection	3724532
152411742	152411765	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAACTGGAGGCTCTCTGAGAGG	FBXW7	ENSG00000109670	0.2507687735697086	[5]	[6,6]	7	hSpCas9	positive selection	3724533
152411656	152411679	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	-0.9742670652852157	[4]	[1,2]	-8	hSpCas9	positive selection	3724534
152411686	152411709	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAATCGTGTGGTAGAGGAGG	FBXW7	ENSG00000109670	0.11080791583075691	[5]	[6,6]	3	hSpCas9	positive selection	3724535
152411653	152411676	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAACTCAGACAACAAGAGGAGG	FBXW7	ENSG00000109670	-0.1309282340891081	[5]	[4,4]	-2	hSpCas9	positive selection	3833137
152411716	152411739	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.6391168787600705	[4]	[1,2]	-7	hSpCas9	positive selection	3833138
152411695	152411718	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGAACAGATGAATCGTGTGG	FBXW7	ENSG00000109670	0.20761654996388057	[5]	[5,4]	5	hSpCas9	positive selection	3833139
152411742	152411765	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAACTGGAGGCTCTCTGAGAGG	FBXW7	ENSG00000109670	0.131804855730991	[5]	[4,6]	3	hSpCas9	positive selection	3833140
152411656	152411679	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.1649894032253602	[5]	[5,4]	4	hSpCas9	positive selection	3833141
152411686	152411709	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAATCGTGTGGTAGAGGAGG	FBXW7	ENSG00000109670	0.20880574054003187	[7]	[6,6]	5	hSpCas9	positive selection	3833142
152382296	152382319	4	-	26780180	A375	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	1.09864818303093	[]	[]	5	hSpCas9	negative selection	3940407
152330759	152330782	4	-	26780180	A375	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	1.80877848506804	[]	[]	9	hSpCas9	negative selection	3940408
152330731	152330754	4	-	26780180	A375	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.488942028013109	[]	[]	1	hSpCas9	negative selection	3940409
152352699	152352722	4	+	26780180	A375	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	-0.123448272983188	[]	[]	-4	hSpCas9	negative selection	3940410
152382184	152382207	4	+	26780180	A375	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.168054041420959	[]	[]	0	hSpCas9	negative selection	3940411
152352711	152352734	4	-	26780180	A375	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	1.07959204813531	[]	[]	5	hSpCas9	negative selection	3940412
152382296	152382319	4	-	26780180	HT29	viability (GeCKOv2 library)	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	1.32035426960591	[]	[]	6	hSpCas9	negative selection	4048373
152330759	152330782	4	-	26780180	HT29	viability (GeCKOv2 library)	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	1.69848060756682	[]	[]	8	hSpCas9	negative selection	4048374
152330731	152330754	4	-	26780180	HT29	viability (GeCKOv2 library)	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.612960379183977	[]	[]	2	hSpCas9	negative selection	4048375
152352699	152352722	4	+	26780180	HT29	viability (GeCKOv2 library)	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	-0.0516943469318651	[]	[]	-1	hSpCas9	negative selection	4048376
152382184	152382207	4	+	26780180	HT29	viability (GeCKOv2 library)	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	1.03181442282608	[]	[]	5	hSpCas9	negative selection	4048377
152352711	152352734	4	-	26780180	HT29	viability (GeCKOv2 library)	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.784163363763941	[]	[]	3	hSpCas9	negative selection	4048378
152330759	152330782	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.3430490372849001	[3]	[3,2]	7	hSpCas9	positive selection	4137387
152330731	152330754	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.0980353474417702	[4]	[2,2]	-2	hSpCas9	positive selection	4137388
152329736	152329759	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCACATGCTTACAGTTTTGTGG	FBXW7	ENSG00000109670	0.20288207921010482	[6]	[4,4]	5	hSpCas9	positive selection	4137389
152329710	152329733	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCAGAACCACTAACTATTCGG	FBXW7	ENSG00000109670	-0.054722140847428324	[4]	[2,3]	-1	hSpCas9	positive selection	4137390
152330784	152330807	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGATGTATGCACTTTTCCATGG	FBXW7	ENSG00000109670	0.05521646652517198	[5]	[3,4]	1	hSpCas9	positive selection	4137391
152329775	152329798	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.4789600452851358	[3]	[2,0]	-8	hSpCas9	positive selection	4137392
152330759	152330782	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.09017772698638665	[5]	[4,4,2,0]	0	hSpCas9	positive selection	4201409
152330731	152330754	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	1.0084436794555214	[4]	[1,0,3,5]	7	hSpCas9	positive selection	4201410
152329736	152329759	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCACATGCTTACAGTTTTGTGG	FBXW7	ENSG00000109670	1.1435276053957404	[6]	[5,4,5,6]	8	hSpCas9	positive selection	4201411
152329710	152329733	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCAGAACCACTAACTATTCGG	FBXW7	ENSG00000109670	0.8937320764434659	[6]	[3,4,6,4]	6	hSpCas9	positive selection	4201412
152330784	152330807	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGATGTATGCACTTTTCCATGG	FBXW7	ENSG00000109670	0.28699368828454275	[5]	[1,1,2,3]	2	hSpCas9	positive selection	4201413
152329775	152329798	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	0.7388124395359379	[4]	[5,5,4,0]	5	hSpCas9	positive selection	4201414
152382184	152382207	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	-0.10954467463735273	[2]	[2,0]	-2	hSpCas9	positive selection	4270842
152352711	152352734	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.7244379181497133	[4]	[4,6]	9	hSpCas9	positive selection	4270843
152352699	152352722	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.339439846337403	[4]	[4,4]	7	hSpCas9	positive selection	4270844
152382296	152382319	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.15299091448323085	[3]	[3,1]	-3	hSpCas9	positive selection	4335106
152330759	152330782	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.38798688719854607	[2]	[2,0]	-7	hSpCas9	positive selection	4335107
152330731	152330754	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.06921952851082924	[0]	[0,0]	-1	hSpCas9	positive selection	4335108
152329775	152329797	4	-	27760321	OCIAML3	viability	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	0.5070143409512506	[141,121]	[101,203]	6	hSpCas9	negative selection	4400781
152330751	152330773	4	-	27760321	OCIAML3	viability	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.6440530329779282	[358,299]	[201,114]	-6	hSpCas9	negative selection	4400782
152330801	152330823	4	-	27760321	OCIAML3	viability	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	0.1317606167896626	[351,286]	[185,384]	1	hSpCas9	negative selection	4400783
152347048	152347070	4	+	27760321	OCIAML3	viability	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.5512903118908642	[429,339]	[234,163]	-5	hSpCas9	negative selection	4400784
152411346	152411368	4	+	27760321	OCIAML3	viability	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	-0.846635753582351	[226,237]	[95,108]	-7	hSpCas9	negative selection	4400785
152411567	152411589	4	+	27760321	OCIAML3	viability	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	0.06649630767165271	[993,932]	[717,882]	0	hSpCas9	negative selection	4400786
152411604	152411626	4	-	27760321	OCIAML3	viability	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	0.2845832743304081	[216,199]	[116,304]	3	hSpCas9	negative selection	4400787
152411634	152411656	4	-	27760321	OCIAML3	viability	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.2845927949676981	[362,309]	[276,374]	3	hSpCas9	negative selection	4400788
152411656	152411678	4	-	27760321	OCIAML3	viability	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.6583586714761144	[293,218]	[302,327]	7	hSpCas9	negative selection	4400789
152411689	152411711	4	-	27760321	OCIAML3	viability	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	-0.07286706468705874	[453,365]	[277,335]	-1	hSpCas9	negative selection	4400790
152329775	152329797	4	-	27760321	OCIAML2	viability	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.19991175022442742	[141,121]	[74,115]	-3	hSpCas9	negative selection	4484244
152330751	152330773	4	-	27760321	OCIAML2	viability	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.21069209403568934	[358,299]	[212,250]	-3	hSpCas9	negative selection	4484245
152330801	152330823	4	-	27760321	OCIAML2	viability	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-0.1666592091952402	[351,286]	[172,302]	-2	hSpCas9	negative selection	4484246
152347048	152347070	4	+	27760321	OCIAML2	viability	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.21519654952533443	[429,339]	[319,410]	3	hSpCas9	negative selection	4484247
152411346	152411368	4	+	27760321	OCIAML2	viability	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.1976401775707165	[226,237]	[158,292]	2	hSpCas9	negative selection	4484248
152411567	152411589	4	+	27760321	OCIAML2	viability	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	0.10933471048210364	[993,932]	[723,995]	1	hSpCas9	negative selection	4484249
152411604	152411626	4	-	27760321	OCIAML2	viability	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.5669604662018841	[216,199]	[93,139]	-6	hSpCas9	negative selection	4484250
152411634	152411656	4	-	27760321	OCIAML2	viability	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	-0.2753217565499493	[362,309]	[193,263]	-3	hSpCas9	negative selection	4484251
152411656	152411678	4	-	27760321	OCIAML2	viability	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.8975276042283766	[293,218]	[336,443]	9	hSpCas9	negative selection	4484252
152411689	152411711	4	-	27760321	OCIAML2	viability	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.3025320715381185	[453,365]	[373,449]	4	hSpCas9	negative selection	4484253
152329775	152329797	4	-	27760321	MV411	viability	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.72465856974374	[141,121]	[0,129]	-5	hSpCas9	negative selection	4567707
152330751	152330773	4	-	27760321	MV411	viability	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-3.6214564588816245	[358,299]	[11,25]	-9	hSpCas9	negative selection	4567708
152330801	152330823	4	-	27760321	MV411	viability	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	1.5350368859308374	[351,286]	[734,416]	9	hSpCas9	negative selection	4567709
152347048	152347070	4	+	27760321	MV411	viability	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.6259050966667419	[429,339]	[134,771]	4	hSpCas9	negative selection	4567710
152411346	152411368	4	+	27760321	MV411	viability	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	-0.5362304242740275	[226,237]	[47,193]	-4	hSpCas9	negative selection	4567711
152411567	152411589	4	+	27760321	MV411	viability	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	0.11683862961754699	[993,932]	[836,468]	0	hSpCas9	negative selection	4567712
152411604	152411626	4	-	27760321	MV411	viability	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	0.9824480663916442	[216,199]	[312,209]	7	hSpCas9	negative selection	4567713
152411634	152411656	4	-	27760321	MV411	viability	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	-0.7404391171598343	[362,309]	[0,329]	-5	hSpCas9	negative selection	4567714
152411656	152411678	4	-	27760321	MV411	viability	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	-0.0753520356395726	[293,218]	[219,67]	0	hSpCas9	negative selection	4567715
152411689	152411711	4	-	27760321	MV411	viability	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.45594769256410206	[453,365]	[213,601]	3	hSpCas9	negative selection	4567716
152329775	152329797	4	-	27760321	HL60	viability	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.23982149836908873	[141,121]	[75,106]	-3	hSpCas9	negative selection	4651170
152330751	152330773	4	-	27760321	HL60	viability	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	1.8398813996486707	[358,299]	[1112,796]	9	hSpCas9	negative selection	4651171
152330801	152330823	4	-	27760321	HL60	viability	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	0.92747635334771	[351,286]	[406,585]	8	hSpCas9	negative selection	4651172
152347048	152347070	4	+	27760321	HL60	viability	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.912874107972562	[429,339]	[468,714]	8	hSpCas9	negative selection	4651173
152411346	152411368	4	+	27760321	HL60	viability	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.5634379883414568	[226,237]	[269,294]	6	hSpCas9	negative selection	4651174
152411567	152411589	4	+	27760321	HL60	viability	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	0.574439746382861	[993,932]	[1116,1231]	6	hSpCas9	negative selection	4651175
152411604	152411626	4	-	27760321	HL60	viability	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.4561059398405072	[216,199]	[128,118]	-5	hSpCas9	negative selection	4651176
152411634	152411656	4	-	27760321	HL60	viability	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.5478636578054848	[362,309]	[286,520]	6	hSpCas9	negative selection	4651177
152411656	152411678	4	-	27760321	HL60	viability	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.42013121972262546	[293,218]	[241,315]	5	hSpCas9	negative selection	4651178
152411689	152411711	4	-	27760321	HL60	viability	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.3523933543543123	[453,365]	[415,434]	4	hSpCas9	negative selection	4651179
152329775	152329797	4	-	27760321	HT1080	viability	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-5.433530874825494	[121,94]	[0,0]	-8	hSpCas9	negative selection	4734633
152330751	152330773	4	-	27760321	HT1080	viability	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-2.1221224733283472	[299,233]	[22,25]	-6	hSpCas9	negative selection	4734634
152330801	152330823	4	-	27760321	HT1080	viability	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-1.6521882002774968	[286,223]	[50,11]	-5	hSpCas9	negative selection	4734635
152347048	152347070	4	+	27760321	HT1080	viability	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.29126283337106473	[339,265]	[120,176]	1	hSpCas9	negative selection	4734636
152411346	152411368	4	+	27760321	HT1080	viability	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	-0.28124611620606343	[237,185]	[58,80]	-1	hSpCas9	negative selection	4734637
152411567	152411589	4	+	27760321	HT1080	viability	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	-1.8423985439573751	[932,727]	[44,143]	-6	hSpCas9	negative selection	4734638
152411604	152411626	4	-	27760321	HT1080	viability	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-2.025923750630841	[199,155]	[4,30]	-6	hSpCas9	negative selection	4734639
152411634	152411656	4	-	27760321	HT1080	viability	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	1.1222193622122438	[309,241]	[77,415]	6	hSpCas9	negative selection	4734640
152411656	152411678	4	-	27760321	HT1080	viability	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.12367308190791948	[218,170]	[76,92]	0	hSpCas9	negative selection	4734641
152411689	152411711	4	-	27760321	HT1080	viability	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.543507388198666	[365,285]	[163,216]	3	hSpCas9	negative selection	4734642
152329775	152329797	4	-	27760321	HT29	viability after 7 days	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-1.1029598988313323	[121,94]	[68,51,73]	-8	hSpCas9	negative selection	4818096
152330751	152330773	4	-	27760321	HT29	viability after 7 days	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.660608873923642	[299,233]	[260,197,198]	-7	hSpCas9	negative selection	4818097
152330801	152330823	4	-	27760321	HT29	viability after 7 days	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	0.0628220904578779	[286,223]	[367,339,324]	0	hSpCas9	negative selection	4818098
152347048	152347070	4	+	27760321	HT29	viability after 7 days	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.05915393072787106	[339,265]	[437,447,337]	0	hSpCas9	negative selection	4818099
152411346	152411368	4	+	27760321	HT29	viability after 7 days	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	-0.008700250646403118	[237,185]	[400,253,178]	0	hSpCas9	negative selection	4818100
152411567	152411589	4	+	27760321	HT29	viability after 7 days	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	-0.298208825045009	[932,727]	[1234,897,533]	-4	hSpCas9	negative selection	4818101
152411604	152411626	4	-	27760321	HT29	viability after 7 days	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	0.21507137328722092	[199,155]	[178,174,424]	3	hSpCas9	negative selection	4818102
152411634	152411656	4	-	27760321	HT29	viability after 7 days	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.29657704631991283	[309,241]	[454,270,578]	4	hSpCas9	negative selection	4818103
152411656	152411678	4	-	27760321	HT29	viability after 7 days	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.8178651112847598	[218,170]	[421,603,300]	9	hSpCas9	negative selection	4818104
152411689	152411711	4	-	27760321	HT29	viability after 7 days	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.2948011725261023	[365,285]	[571,491,486]	4	hSpCas9	negative selection	4818105
152329775	152329797	4	-	27760321	HT29	viability after 25 days	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-1.8981390970018883	[121,94]	[34,53,7]	-8	hSpCas9	negative selection	4901559
152330751	152330773	4	-	27760321	HT29	viability after 25 days	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-2.291752210715975	[299,233]	[65,54,65]	-8	hSpCas9	negative selection	4901560
152330801	152330823	4	-	27760321	HT29	viability after 25 days	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-1.035828182140754	[286,223]	[136,176,109]	-6	hSpCas9	negative selection	4901561
152347048	152347070	4	+	27760321	HT29	viability after 25 days	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.2340156857485334	[339,265]	[67,174,209]	-7	hSpCas9	negative selection	4901562
152411346	152411368	4	+	27760321	HT29	viability after 25 days	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.41862640197989925	[237,185]	[294,387,285]	4	hSpCas9	negative selection	4901563
152411567	152411589	4	+	27760321	HT29	viability after 25 days	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	0.11679643687514574	[932,727]	[918,754,1463]	1	hSpCas9	negative selection	4901564
152411604	152411626	4	-	27760321	HT29	viability after 25 days	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.3541382721509976	[199,155]	[38,180,276]	-4	hSpCas9	negative selection	4901565
152411634	152411656	4	-	27760321	HT29	viability after 25 days	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.7082661487114096	[309,241]	[699,297,537]	7	hSpCas9	negative selection	4901566
152411656	152411678	4	-	27760321	HT29	viability after 25 days	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.7673554888667219	[218,170]	[376,368,392]	8	hSpCas9	negative selection	4901567
152411689	152411711	4	-	27760321	HT29	viability after 25 days	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.11750233268245405	[365,285]	[235,509,484]	1	hSpCas9	negative selection	4901568
152329775	152329797	4	-	27760321	HT29	viability after 22 days	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-1.989279629058963	[121,94]	[48,43,0]	-8	hSpCas9	negative selection	4985022
152330751	152330773	4	-	27760321	HT29	viability after 22 days	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-2.29039916289923	[299,233]	[9,87,92]	-8	hSpCas9	negative selection	4985023
152330801	152330823	4	-	27760321	HT29	viability after 22 days	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-2.329525528938572	[286,223]	[64,64,45]	-8	hSpCas9	negative selection	4985024
152347048	152347070	4	+	27760321	HT29	viability after 22 days	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.8559337086530737	[339,265]	[159,184,236]	-6	hSpCas9	negative selection	4985025
152411346	152411368	4	+	27760321	HT29	viability after 22 days	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	1.1325644220793982	[237,185]	[292,655,670]	9	hSpCas9	negative selection	4985026
152411567	152411589	4	+	27760321	HT29	viability after 22 days	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	-0.22916336003367266	[932,727]	[835,878,740]	-2	hSpCas9	negative selection	4985027
152411604	152411626	4	-	27760321	HT29	viability after 22 days	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.4554344858002455	[199,155]	[208,151,86]	-4	hSpCas9	negative selection	4985028
152411634	152411656	4	-	27760321	HT29	viability after 22 days	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.5594777634045903	[309,241]	[667,405,329]	6	hSpCas9	negative selection	4985029
152411656	152411678	4	-	27760321	HT29	viability after 22 days	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.7060855791913475	[218,170]	[268,569,265]	7	hSpCas9	negative selection	4985030
152411689	152411711	4	-	27760321	HT29	viability after 22 days	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.23226597437682614	[365,285]	[291,729,308]	2	hSpCas9	negative selection	4985031
152329775	152329797	4	-	27760321	HT29	viability after 19 days	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-2.729844525437578	[121,94]	[58,0,0]	-8	hSpCas9	negative selection	5068485
152330751	152330773	4	-	27760321	HT29	viability after 19 days	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-3.583114021804	[299,233]	[64,1,13]	-9	hSpCas9	negative selection	5068486
152330801	152330823	4	-	27760321	HT29	viability after 19 days	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-1.319983791361185	[286,223]	[131,113,106]	-7	hSpCas9	negative selection	5068487
152347048	152347070	4	+	27760321	HT29	viability after 19 days	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.5876643659937896	[339,265]	[155,272,253]	-5	hSpCas9	negative selection	5068488
152411346	152411368	4	+	27760321	HT29	viability after 19 days	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.022232308604751894	[237,185]	[350,137,259]	0	hSpCas9	negative selection	5068489
152411567	152411589	4	+	27760321	HT29	viability after 19 days	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	0.1260942434390846	[932,727]	[749,1292,1035]	1	hSpCas9	negative selection	5068490
152411604	152411626	4	-	27760321	HT29	viability after 19 days	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.19798439863080297	[199,155]	[127,111,282]	-2	hSpCas9	negative selection	5068491
152411634	152411656	4	-	27760321	HT29	viability after 19 days	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	1.4634375927221026	[309,241]	[607,317,1627]	9	hSpCas9	negative selection	5068492
152411656	152411678	4	-	27760321	HT29	viability after 19 days	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	1.1956649478583818	[218,170]	[703,246,597]	9	hSpCas9	negative selection	5068493
152411689	152411711	4	-	27760321	HT29	viability after 19 days	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.2333460432100069	[365,285]	[407,531,373]	2	hSpCas9	negative selection	5068494
152329775	152329797	4	-	27760321	HT29	viability after 16 days	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-1.512552119044066	[121,94]	[58,48,20]	-8	hSpCas9	negative selection	5151948
152330751	152330773	4	-	27760321	HT29	viability after 16 days	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-2.40207779929931	[299,233]	[93,20,58]	-8	hSpCas9	negative selection	5151949
152330801	152330823	4	-	27760321	HT29	viability after 16 days	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-0.685261913789545	[286,223]	[93,191,238]	-6	hSpCas9	negative selection	5151950
152347048	152347070	4	+	27760321	HT29	viability after 16 days	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.14136483038640907	[339,265]	[641,301,204]	1	hSpCas9	negative selection	5151951
152411346	152411368	4	+	27760321	HT29	viability after 16 days	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.4343885075019884	[237,185]	[356,359,246]	5	hSpCas9	negative selection	5151952
152411567	152411589	4	+	27760321	HT29	viability after 16 days	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	-0.1134043660763906	[932,727]	[956,738,892]	-1	hSpCas9	negative selection	5151953
152411604	152411626	4	-	27760321	HT29	viability after 16 days	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.2716423698269401	[199,155]	[87,110,289]	-3	hSpCas9	negative selection	5151954
152411634	152411656	4	-	27760321	HT29	viability after 16 days	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.1716667676127961	[309,241]	[362,225,458]	1	hSpCas9	negative selection	5151955
152411656	152411678	4	-	27760321	HT29	viability after 16 days	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.42702475753504543	[218,170]	[240,330,301]	5	hSpCas9	negative selection	5151956
152411689	152411711	4	-	27760321	HT29	viability after 16 days	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.4581735479065834	[365,285]	[257,587,631]	5	hSpCas9	negative selection	5151957
152329775	152329797	4	-	27760321	HT29	viability after 13 days	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.7170364229746098	[121,94]	[136,40,52]	-6	hSpCas9	negative selection	5235411
152330751	152330773	4	-	27760321	HT29	viability after 13 days	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-1.0624517117185461	[299,233]	[31,261,150]	-7	hSpCas9	negative selection	5235412
152330801	152330823	4	-	27760321	HT29	viability after 13 days	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-0.9171700701800942	[286,223]	[122,157,187]	-7	hSpCas9	negative selection	5235413
152347048	152347070	4	+	27760321	HT29	viability after 13 days	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.02919434789537309	[339,265]	[359,303,367]	0	hSpCas9	negative selection	5235414
152411346	152411368	4	+	27760321	HT29	viability after 13 days	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.5826646667465563	[237,185]	[530,313,265]	7	hSpCas9	negative selection	5235415
152411567	152411589	4	+	27760321	HT29	viability after 13 days	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	-0.18475273746340126	[932,727]	[957,710,871]	-2	hSpCas9	negative selection	5235416
152411604	152411626	4	-	27760321	HT29	viability after 13 days	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.2509536888291648	[199,155]	[128,121,263]	-3	hSpCas9	negative selection	5235417
152411634	152411656	4	-	27760321	HT29	viability after 13 days	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.4516033129753485	[309,241]	[490,376,444]	6	hSpCas9	negative selection	5235418
152411656	152411678	4	-	27760321	HT29	viability after 13 days	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.9168285374990595	[218,170]	[837,231,222]	9	hSpCas9	negative selection	5235419
152411689	152411711	4	-	27760321	HT29	viability after 13 days	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	0.038452358539647374	[365,285]	[342,461,361]	0	hSpCas9	negative selection	5235420
152329775	152329797	4	-	27760321	HT29	viability after 10 days	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.6540801717178972	[121,94]	[71,27,154]	-6	hSpCas9	negative selection	5318874
152330751	152330773	4	-	27760321	HT29	viability after 10 days	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.682284271056468	[299,233]	[321,132,166]	-7	hSpCas9	negative selection	5318875
152330801	152330823	4	-	27760321	HT29	viability after 10 days	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-0.5089012271009541	[286,223]	[180,152,333]	-6	hSpCas9	negative selection	5318876
152347048	152347070	4	+	27760321	HT29	viability after 10 days	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.12272980279619569	[339,265]	[333,363,344]	-2	hSpCas9	negative selection	5318877
152411346	152411368	4	+	27760321	HT29	viability after 10 days	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.24424432853228906	[237,185]	[287,272,376]	3	hSpCas9	negative selection	5318878
152411567	152411589	4	+	27760321	HT29	viability after 10 days	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	-0.22107961589689729	[932,727]	[1015,539,1097]	-3	hSpCas9	negative selection	5318879
152411604	152411626	4	-	27760321	HT29	viability after 10 days	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-0.3165966207436728	[199,155]	[176,212,146]	-4	hSpCas9	negative selection	5318880
152411634	152411656	4	-	27760321	HT29	viability after 10 days	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	0.3892221371335045	[309,241]	[750,238,359]	5	hSpCas9	negative selection	5318881
152411656	152411678	4	-	27760321	HT29	viability after 10 days	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.7221905062675636	[218,170]	[305,285,604]	8	hSpCas9	negative selection	5318882
152411689	152411711	4	-	27760321	HT29	viability after 10 days	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	-0.021117739185401274	[365,285]	[614,257,327]	0	hSpCas9	negative selection	5318883
152329775	152329797	4	-	27760321	MOLM13	viability	CTTTCTTATAGGTGCTGAAAGG	FBXW7	ENSG00000109670	-0.049289674318344856	[141,121]	[0,131]	0	hSpCas9	negative selection	5402337
152330751	152330773	4	-	27760321	MOLM13	viability	TTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.980216042453586	[358,299]	[189,11]	-5	hSpCas9	negative selection	5402338
152330801	152330823	4	-	27760321	MOLM13	viability	AGGTTTCATACACAGTCCATGG	FBXW7	ENSG00000109670	-2.4088071197149707	[351,286]	[56,13]	-8	hSpCas9	negative selection	5402339
152347048	152347070	4	+	27760321	MOLM13	viability	GAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.463327639875517	[429,339]	[87,69]	-7	hSpCas9	negative selection	5402340
152411346	152411368	4	+	27760321	MOLM13	viability	GGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	-3.0501318911530966	[226,237]	[16,14]	-9	hSpCas9	negative selection	5402341
152411567	152411589	4	+	27760321	MOLM13	viability	TTCTTCCAACTGTCCTTGCTGG	FBXW7	ENSG00000109670	-0.5715518250652957	[993,932]	[378,354]	-4	hSpCas9	negative selection	5402342
152411604	152411626	4	-	27760321	MOLM13	viability	TTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	-1.6035619338208076	[216,199]	[82,0]	-7	hSpCas9	negative selection	5402343
152411634	152411656	4	-	27760321	MOLM13	viability	AGGAGCACACTGCAAGGAATGG	FBXW7	ENSG00000109670	-1.6634344372922516	[362,309]	[116,10]	-7	hSpCas9	negative selection	5402344
152411656	152411678	4	-	27760321	MOLM13	viability	CAGCAACTCAGACAACAAGAGG	FBXW7	ENSG00000109670	0.13958887859999125	[293,218]	[197,123]	0	hSpCas9	negative selection	5402345
152411689	152411711	4	-	27760321	MOLM13	viability	CAGATGAATCGTGTGGTAGAGG	FBXW7	ENSG00000109670	-0.2528440034694291	[453,365]	[124,250]	-2	hSpCas9	negative selection	5402346
152411325	152411348	4	+	27661255	K562	viability	GGGGAGGAGAGTTGGTGAACGGG	FBXW7	ENSG00000109670	0.14654818432045136	[778,1017]	[808,774]	5	dCas9-KRAB	negative selection	5479874
152411345	152411368	4	+	27661255	K562	viability	GGGCAGGTCCACAATACTACTGG	FBXW7	ENSG00000109670	0.1373201810111201	[1185,1439]	[1209,1097]	5	dCas9-KRAB	negative selection	5479875
152534958	152534981	4	+	27661255	K562	viability	GCGGCGCCGAGAAAGTGGGTTGG	FBXW7	ENSG00000109670	0.36841586422777195	[310,490]	[434,388]	9	dCas9-KRAB	negative selection	5479876
152535004	152535027	4	+	27661255	K562	viability	GCGGCAGCTGCGGAAGGCTCCGG	FBXW7	ENSG00000109670	0.5728486250620239	[157,369]	[286,327]	9	dCas9-KRAB	negative selection	5479877
152535634	152535657	4	+	27661255	K562	viability	GGCTCCCGCATGTGTCGCTGCGG	FBXW7	ENSG00000109670	0.2535248237685669	[479,569]	[607,404]	8	dCas9-KRAB	negative selection	5479878
152535684	152535707	4	+	27661255	K562	viability	GGTCTCGCCCCACGCCCCACGGG	FBXW7	ENSG00000109670	0.1980589834310258	[1328,1547]	[1482,1170]	6	dCas9-KRAB	negative selection	5479879
152411604	152411627	4	-	27661255	K562	viability	GTTGGAGTAGAACCTAGACCTGG	FBXW7	ENSG00000109670	0.10708089794275621	[1013,1128]	[979,868]	4	dCas9-KRAB	negative selection	5479880
152411686	152411709	4	-	27661255	K562	viability	GATGAATCGTGTGGTAGAGGAGG	FBXW7	ENSG00000109670	0.03624811047741705	[1276,1179]	[1166,871]	1	dCas9-KRAB	negative selection	5479881
152411757	152411780	4	-	27661255	K562	viability	GGCAGCAAAAGACGACGAACTGG	FBXW7	ENSG00000109670	0.10610537915004004	[1321,1344]	[1157,1135]	3	dCas9-KRAB	negative selection	5479882
152535667	152535690	4	-	27661255	K562	viability	GAGACCCCCAAGGTGTAGGGAGG	FBXW7	ENSG00000109670	0.23022928737728987	[543,534]	[516,495]	7	dCas9-KRAB	negative selection	5479883
152535670	152535693	4	-	27661255	K562	viability	GGCGAGACCCCCAAGGTGTAGGG	FBXW7	ENSG00000109670	-0.026263729179897055	[294,423]	[304,258]	-1	dCas9-KRAB	negative selection	5479884
152535677	152535700	4	-	27661255	K562	viability	GGCGTGGGGCGAGACCCCCAAGG	FBXW7	ENSG00000109670	-0.053517971719620305	[652,498]	[465,427]	-2	dCas9-KRAB	negative selection	5479885
152536054	152536077	4	-	27661255	K562	viability	GAGAGCCCCGCACAGAGCGAGGG	FBXW7	ENSG00000109670	-0.1072838843980903	[742,1044]	[747,582]	-4	dCas9-KRAB	negative selection	5479886
152382184	152382207	4	+	27260156	BXPC3	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.2154614839854292	[222]	[279,259,298,237]	5	hSpCas9	negative selection	5543302
152352711	152352734	4	-	27260156	BXPC3	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.07229806253136473	[1148]	[1094,1362,1262,1344]	1	hSpCas9	negative selection	5543303
152352699	152352722	4	+	27260156	BXPC3	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.24089597035382848	[1460]	[1395,1814,1856,2238]	5	hSpCas9	negative selection	5543304
152382296	152382319	4	-	27260156	BXPC3	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.1972313753987861	[920]	[899,721,794,949]	-4	hSpCas9	negative selection	5607566
152330759	152330782	4	-	27260156	BXPC3	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.07658454468922993	[426]	[421,545,378,322]	-2	hSpCas9	negative selection	5607567
152330731	152330754	4	-	27260156	BXPC3	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.49585159347957486	[53]	[4,41,62,55]	-8	hSpCas9	negative selection	5607568
152382184	152382207	4	+	27260156	A673	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.21278154939677763	[222]	[313,271,297,360]	5	hSpCas9	negative selection	5664553
152352711	152352734	4	-	27260156	A673	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.06156994963410267	[1148]	[1660,1341,1203,1105]	-1	hSpCas9	negative selection	5664554
152352699	152352722	4	+	27260156	A673	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.1371645971264921	[1460]	[2183,1823,1886,1845]	3	hSpCas9	negative selection	5664555
152382296	152382319	4	-	27260156	A673	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	0.006979528588033745	[920]	[1051,1148,1060,1176]	0	hSpCas9	negative selection	5728817
152330759	152330782	4	-	27260156	A673	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.24929607705040308	[426]	[380,352,519,467]	-6	hSpCas9	negative selection	5728818
152330731	152330754	4	-	27260156	A673	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.9089820818317866	[53]	[34,48,31,20]	-9	hSpCas9	negative selection	5728819
152382184	152382207	4	+	27260156	A375	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.7343189805934807	[222]	[586,425,417,314]	9	hSpCas9	negative selection	5785804
152352711	152352734	4	-	27260156	A375	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.24950246345700244	[1148]	[1390,1108,887,1122]	-4	hSpCas9	negative selection	5785805
152352699	152352722	4	+	27260156	A375	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.4727044456289444	[1460]	[2515,2739,2328,1977]	7	hSpCas9	negative selection	5785806
152382296	152382319	4	-	27260156	A375	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.4813086441238916	[920]	[773,705,779,805]	-6	hSpCas9	negative selection	5850068
152330759	152330782	4	-	27260156	A375	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.434808029756943	[426]	[383,306,406,367]	-6	hSpCas9	negative selection	5850069
152330731	152330754	4	-	27260156	A375	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.2464337831598611	[53]	[49,60,25,73]	-4	hSpCas9	negative selection	5850070
152382184	152382207	4	+	27260156	COLO741	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.43098820934784576	[222]	[424,374,356]	8	hSpCas9	negative selection	5907055
152352711	152352734	4	-	27260156	COLO741	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.029782608198993143	[1148]	[1653,1664,1208]	0	hSpCas9	negative selection	5907056
152352699	152352722	4	+	27260156	COLO741	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.36451024084285	[1460]	[2665,2431,2147]	7	hSpCas9	negative selection	5907057
152382296	152382319	4	-	27260156	COLO741	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.263486919611989	[920]	[961,1004,970]	-5	hSpCas9	negative selection	5971319
152330759	152330782	4	-	27260156	COLO741	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.05273894470724	[426]	[492,458,725]	1	hSpCas9	negative selection	5971320
152330731	152330754	4	-	27260156	COLO741	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.9425777365179648	[53]	[24,7,70]	-9	hSpCas9	negative selection	5971321
152382184	152382207	4	+	27260156	CAL120	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	-0.025230370749342645	[222]	[234,288,287]	0	hSpCas9	negative selection	6028306
152352711	152352734	4	-	27260156	CAL120	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.2527209340842631	[1148]	[1282,1065,1261]	-4	hSpCas9	negative selection	6028307
152352699	152352722	4	+	27260156	CAL120	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.4496701526954021	[1460]	[1732,3229,2373]	6	hSpCas9	negative selection	6028308
152382296	152382319	4	-	27260156	CAL120	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.24430841206577647	[920]	[1100,1059,764]	-4	hSpCas9	negative selection	6092570
152330759	152330782	4	-	27260156	CAL120	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.25814992070698234	[426]	[952,425,575]	4	hSpCas9	negative selection	6092571
152330731	152330754	4	-	27260156	CAL120	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-1.449998177214761	[53]	[18,32,20]	-9	hSpCas9	negative selection	6092572
152382184	152382207	4	+	27260156	CADOES1	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.06187938249673475	[222]	[188,218,267,188]	1	hSpCas9	negative selection	6149557
152352711	152352734	4	-	27260156	CADOES1	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.334536585442477	[1148]	[804,944,746,894]	-5	hSpCas9	negative selection	6149558
152352699	152352722	4	+	27260156	CADOES1	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.46738709480592067	[1460]	[1802,1744,2206,1754]	7	hSpCas9	negative selection	6149559
152382296	152382319	4	-	27260156	CADOES1	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.471133991972533	[920]	[503,660,691,614]	-7	hSpCas9	negative selection	6213821
152330759	152330782	4	-	27260156	CADOES1	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.11126463125754085	[426]	[306,378,411,372]	-2	hSpCas9	negative selection	6213822
152330731	152330754	4	-	27260156	CADOES1	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.025983818676809545	[53]	[27,71,18,86]	0	hSpCas9	negative selection	6213823
152382184	152382207	4	+	27260156	EWS502	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.2253600758843216	[222]	[244,302,413,135]	4	hSpCas9	negative selection	6270808
152352711	152352734	4	-	27260156	EWS502	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.12600034847383923	[1148]	[993,1062,1142,1285]	-2	hSpCas9	negative selection	6270809
152352699	152352722	4	+	27260156	EWS502	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.17627282740469852	[1460]	[1538,1709,2040,1726]	3	hSpCas9	negative selection	6270810
152382296	152382319	4	-	27260156	EWS502	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.23633244995418956	[920]	[554,859,761,1188]	-4	hSpCas9	negative selection	6335072
152330759	152330782	4	-	27260156	EWS502	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.48548650677383176	[426]	[301,206,422,370]	-7	hSpCas9	negative selection	6335073
152330731	152330754	4	-	27260156	EWS502	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.2239909110014655	[53]	[20,52,32,94]	-4	hSpCas9	negative selection	6335074
152382184	152382207	4	+	27260156	EW8	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.6502180088160698	[222]	[419,130,252,348]	9	hSpCas9	negative selection	6392059
152352711	152352734	4	-	27260156	EW8	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.09321610319771456	[1148]	[1158,1062,738,1070]	1	hSpCas9	negative selection	6392060
152352699	152352722	4	+	27260156	EW8	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.25518386796904236	[1460]	[1725,1328,1202,1459]	5	hSpCas9	negative selection	6392061
152382296	152382319	4	-	27260156	EW8	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.2059928698315887	[920]	[699,830,405,696]	-4	hSpCas9	negative selection	6456323
152330759	152330782	4	-	27260156	EW8	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.14895099561649083	[426]	[314,418,195,337]	-3	hSpCas9	negative selection	6456324
152330731	152330754	4	-	27260156	EW8	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.46480770801952165	[53]	[31,110,21,79]	8	hSpCas9	negative selection	6456325
152382184	152382207	4	+	27260156	CORL105	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.42789793708395685	[222]	[436,292,376,305]	7	hSpCas9	negative selection	6513310
152352711	152352734	4	-	27260156	CORL105	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.25195924323044694	[1148]	[1330,1123,1093,970]	-5	hSpCas9	negative selection	6513311
152352699	152352722	4	+	27260156	CORL105	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.14810228017084004	[1460]	[1764,1985,1988,1848]	2	hSpCas9	negative selection	6513312
152382296	152382319	4	-	27260156	CORL105	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.38910830122243534	[920]	[912,804,1043,569]	-6	hSpCas9	negative selection	6577574
152330759	152330782	4	-	27260156	CORL105	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.05559238333957714	[426]	[482,498,601,505]	1	hSpCas9	negative selection	6577575
152330731	152330754	4	-	27260156	CORL105	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.11536237541598338	[53]	[107,59,43,20]	-2	hSpCas9	negative selection	6577576
152382184	152382207	4	+	27260156	HS294T	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.3499403678556101	[222]	[102,125,101,107]	5	hSpCas9	negative selection	6634561
152352711	152352734	4	-	27260156	HS294T	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.5213545375281518	[1148]	[189,293,281,517]	-6	hSpCas9	negative selection	6634562
152352699	152352722	4	+	27260156	HS294T	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.4488839576828918	[1460]	[678,635,935,858]	6	hSpCas9	negative selection	6634563
152382296	152382319	4	-	27260156	HS294T	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.39545734672950406	[920]	[182,181,405,332]	-5	hSpCas9	negative selection	6698825
152330759	152330782	4	-	27260156	HS294T	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.05407789873511895	[426]	[141,108,147,314]	0	hSpCas9	negative selection	6698826
152330731	152330754	4	-	27260156	HS294T	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.9639590900083412	[53]	[20,42,27,78]	9	hSpCas9	negative selection	6698827
152382184	152382207	4	+	27260156	HCC44	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.2877653058439943	[222]	[246,281,435,284]	5	hSpCas9	negative selection	6755812
152352711	152352734	4	-	27260156	HCC44	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.34215161187928156	[1148]	[1388,820,1120,845]	-5	hSpCas9	negative selection	6755813
152352699	152352722	4	+	27260156	HCC44	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.4311713647821376	[1460]	[2541,1736,2574,2198]	7	hSpCas9	negative selection	6755814
152382296	152382319	4	-	27260156	HCC44	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.2098216393480149	[920]	[999,726,941,964]	-3	hSpCas9	negative selection	6820076
152330759	152330782	4	-	27260156	HCC44	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.40942580582081695	[426]	[588,649,619,689]	6	hSpCas9	negative selection	6820077
152330731	152330754	4	-	27260156	HCC44	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-1.300604982528486	[53]	[10,27,39,20]	-9	hSpCas9	negative selection	6820078
152382184	152382207	4	+	27260156	G402	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	1.001997934413313	[222]	[871,306,335,688]	9	hSpCas9	negative selection	6877063
152352711	152352734	4	-	27260156	G402	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.09581502045182311	[1148]	[1343,1558,1300,1751]	1	hSpCas9	negative selection	6877064
152352699	152352722	4	+	27260156	G402	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.4592139669912372	[1460]	[2605,2638,2125,2455]	6	hSpCas9	negative selection	6877065
152382296	152382319	4	-	27260156	G402	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.27165748720842176	[920]	[1102,641,1112,872]	-3	hSpCas9	negative selection	6941327
152330759	152330782	4	-	27260156	G402	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.6450979355816546	[426]	[360,267,419,284]	-7	hSpCas9	negative selection	6941328
152330731	152330754	4	-	27260156	G402	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.10475595800337922	[53]	[166,39,13,38]	-1	hSpCas9	negative selection	6941329
152382184	152382207	4	+	27260156	L33	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.1477204606249315	[222]	[248,117,138,229]	3	hSpCas9	negative selection	6998314
152352711	152352734	4	-	27260156	L33	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.27631520471399984	[1148]	[885,397,666,878]	-6	hSpCas9	negative selection	6998315
152352699	152352722	4	+	27260156	L33	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.10150016175193222	[1460]	[1564,603,943,1726]	2	hSpCas9	negative selection	6998316
152382296	152382319	4	-	27260156	L33	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.3204587003661974	[920]	[777,247,540,705]	-6	hSpCas9	negative selection	7062578
152330759	152330782	4	-	27260156	L33	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.016363432321187033	[426]	[516,144,229,448]	0	hSpCas9	negative selection	7062579
152330731	152330754	4	-	27260156	L33	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.09006642834479939	[53]	[67,17,41,50]	2	hSpCas9	negative selection	7062580
152382184	152382207	4	+	27260156	K562	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.510585151957127	[222]	[100,520,349,165]	6	hSpCas9	negative selection	7119565
152352711	152352734	4	-	27260156	K562	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.024888980650726644	[1148]	[965,972,1263,943]	0	hSpCas9	negative selection	7119566
152352699	152352722	4	+	27260156	K562	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.5539245651170563	[1460]	[2054,2254,2211,1197]	7	hSpCas9	negative selection	7119567
152382296	152382319	4	-	27260156	K562	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.25196479514114767	[920]	[588,879,884,421]	-3	hSpCas9	negative selection	7183829
152330759	152330782	4	-	27260156	K562	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.1422307474980113	[426]	[587,362,444,299]	1	hSpCas9	negative selection	7183830
152330731	152330754	4	-	27260156	K562	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-1.9791973398220426	[53]	[3,26,17,0]	-9	hSpCas9	negative selection	7183831
152382184	152382207	4	+	27260156	HT29	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.3199541769740525	[222]	[455,274,341,287]	6	hSpCas9	negative selection	7240816
152352711	152352734	4	-	27260156	HT29	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.12945304844777206	[1148]	[1432,1822,1528,1354]	2	hSpCas9	negative selection	7240817
152352699	152352722	4	+	27260156	HT29	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.3372519111414718	[1460]	[2388,2352,2082,2163]	6	hSpCas9	negative selection	7240818
152382296	152382319	4	-	27260156	HT29	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.0777648266729366	[920]	[1316,1109,937,912]	-2	hSpCas9	negative selection	7305080
152330759	152330782	4	-	27260156	HT29	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.31707066466809486	[426]	[380,517,402,372]	-6	hSpCas9	negative selection	7305081
152330731	152330754	4	-	27260156	HT29	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.6642456209148615	[53]	[24,47,70,22]	-8	hSpCas9	negative selection	7305082
152382184	152382207	4	+	27260156	MHHES1	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.5806065725708353	[222]	[478,394,412,250]	8	hSpCas9	negative selection	7362067
152352711	152352734	4	-	27260156	MHHES1	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.24969654047981127	[1148]	[1286,1285,901,932]	-5	hSpCas9	negative selection	7362068
152352699	152352722	4	+	27260156	MHHES1	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.2260481787708395	[1460]	[1891,2190,2042,1622]	4	hSpCas9	negative selection	7362069
152382296	152382319	4	-	27260156	MHHES1	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.30539849130649244	[920]	[1040,839,953,587]	-5	hSpCas9	negative selection	7426331
152330759	152330782	4	-	27260156	MHHES1	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.48258618116614616	[426]	[326,319,426,300]	-7	hSpCas9	negative selection	7426332
152330731	152330754	4	-	27260156	MHHES1	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.06951010256752532	[53]	[119,65,63,20]	1	hSpCas9	negative selection	7426333
152382184	152382207	4	+	27260156	MEWO	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.3792252094258737	[222]	[303,337,177]	7	hSpCas9	negative selection	7483318
152352711	152352734	4	-	27260156	MEWO	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.11355636726955542	[1148]	[1075,895,1024]	-2	hSpCas9	negative selection	7483319
152352699	152352722	4	+	27260156	MEWO	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.14889333350866907	[1460]	[1902,1334,1383]	3	hSpCas9	negative selection	7483320
152382296	152382319	4	-	27260156	MEWO	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.2377647973585909	[920]	[867,653,696]	-5	hSpCas9	negative selection	7547582
152330759	152330782	4	-	27260156	MEWO	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.14472400279202646	[426]	[526,171,417]	-3	hSpCas9	negative selection	7547583
152330731	152330754	4	-	27260156	MEWO	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.8714086109647967	[53]	[71,152,47]	9	hSpCas9	negative selection	7547584
152382184	152382207	4	+	27260156	LNCAPCLONEFGC	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.5712446824700247	[222]	[291,206,335,376]	8	hSpCas9	negative selection	7604569
152352711	152352734	4	-	27260156	LNCAPCLONEFGC	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.5031215393036961	[1148]	[642,617,986,735]	-6	hSpCas9	negative selection	7604570
152352699	152352722	4	+	27260156	LNCAPCLONEFGC	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.42066156271270905	[1460]	[1678,1674,1919,1840]	6	hSpCas9	negative selection	7604571
152382296	152382319	4	-	27260156	LNCAPCLONEFGC	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.5841396063185227	[920]	[520,556,587,564]	-7	hSpCas9	negative selection	7668833
152330759	152330782	4	-	27260156	LNCAPCLONEFGC	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-1.019590786157107	[426]	[180,157,268,168]	-8	hSpCas9	negative selection	7668834
152330731	152330754	4	-	27260156	LNCAPCLONEFGC	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-1.5514613209670172	[53]	[21,16,25,2]	-9	hSpCas9	negative selection	7668835
152382184	152382207	4	+	27260156	PANC0327	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.5758278469891893	[222]	[289,382,180,314]	8	hSpCas9	negative selection	7725820
152352711	152352734	4	-	27260156	PANC0327	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.08362609071223415	[1148]	[1176,1180,1036,925]	1	hSpCas9	negative selection	7725821
152352699	152352722	4	+	27260156	PANC0327	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.2742418999762506	[1460]	[1515,1399,1581,1796]	4	hSpCas9	negative selection	7725822
152382296	152382319	4	-	27260156	PANC0327	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	0.1690630647674084	[920]	[951,1073,924,710]	2	hSpCas9	negative selection	7790084
152330759	152330782	4	-	27260156	PANC0327	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.8713909086242105	[426]	[177,204,138,304]	-8	hSpCas9	negative selection	7790085
152330731	152330754	4	-	27260156	PANC0327	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.5444674270855545	[53]	[28,49,19,29]	-6	hSpCas9	negative selection	7790086
152382184	152382207	4	+	27260156	NCIH2009	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.3945360277783977	[222]	[482,381,377]	5	hSpCas9	negative selection	7847071
152352711	152352734	4	-	27260156	NCIH2009	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.24988133518642042	[1148]	[1976,838,1364]	-3	hSpCas9	negative selection	7847072
152352699	152352722	4	+	27260156	NCIH2009	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.3277098862650305	[1460]	[2852,2650,2232]	4	hSpCas9	negative selection	7847073
152382296	152382319	4	-	27260156	NCIH2009	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-1.046418225197708	[920]	[736,541,612]	-8	hSpCas9	negative selection	7911335
152330759	152330782	4	-	27260156	NCIH2009	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.9183127039745799	[426]	[325,288,333]	-8	hSpCas9	negative selection	7911336
152330731	152330754	4	-	27260156	NCIH2009	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.35926539809792857	[53]	[33,27,109]	-5	hSpCas9	negative selection	7911337
152382184	152382207	4	+	27260156	NCIH1373	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.769184786949629	[222]	[475,265,212,209]	7	hSpCas9	negative selection	7968322
152352711	152352734	4	-	27260156	NCIH1373	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.7352768999688687	[1148]	[1691,516,293,201]	-6	hSpCas9	negative selection	7968323
152352699	152352722	4	+	27260156	NCIH1373	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.8237205940717895	[1460]	[4034,2268,2797,712]	7	hSpCas9	negative selection	7968324
152382296	152382319	4	-	27260156	NCIH1373	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.7962727032254759	[920]	[640,425,445,238]	-7	hSpCas9	negative selection	8032586
152330759	152330782	4	-	27260156	NCIH1373	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.19633899384979187	[426]	[433,294,607,88]	-2	hSpCas9	negative selection	8032587
152330731	152330754	4	-	27260156	NCIH1373	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.25950708529958	[53]	[29,71,44,12]	-3	hSpCas9	negative selection	8032588
152382184	152382207	4	+	27260156	PATU8902	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.4486281685182506	[222]	[628,374,242,497]	4	hSpCas9	negative selection	8089573
152352711	152352734	4	-	27260156	PATU8902	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.4860920027244635	[1148]	[2377,2201,1673,2919]	5	hSpCas9	negative selection	8089574
152352699	152352722	4	+	27260156	PATU8902	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.6579431547259567	[1460]	[2993,3614,2485,4008]	7	hSpCas9	negative selection	8089575
152382296	152382319	4	-	27260156	PATU8902	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.020359475946304384	[920]	[969,1037,1001,2224]	0	hSpCas9	negative selection	8153837
152330759	152330782	4	-	27260156	PATU8902	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	1.4417995059551885	[426]	[1593,1634,1503,1762]	9	hSpCas9	negative selection	8153838
152330731	152330754	4	-	27260156	PATU8902	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.26099970360219427	[53]	[62,232,47,18]	2	hSpCas9	negative selection	8153839
152382184	152382207	4	+	27260156	PANC1	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.8982997748393781	[222]	[322,400,464,259]	9	hSpCas9	negative selection	8210824
152352711	152352734	4	-	27260156	PANC1	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.043683726642799625	[1148]	[889,1395,914,942]	0	hSpCas9	negative selection	8210825
152352699	152352722	4	+	27260156	PANC1	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.5118180089607696	[1460]	[2139,2288,1557,1312]	8	hSpCas9	negative selection	8210826
152382296	152382319	4	-	27260156	PANC1	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	0.10001941539041737	[920]	[613,1329,628,897]	1	hSpCas9	negative selection	8275088
152330759	152330782	4	-	27260156	PANC1	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.22320066778416314	[426]	[301,381,172,393]	-4	hSpCas9	negative selection	8275089
152330731	152330754	4	-	27260156	PANC1	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.32472121962021916	[53]	[8,71,21,49]	-5	hSpCas9	negative selection	8275090
152382184	152382207	4	+	27260156	PANC0813	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.4491862392160083	[222]	[509,379,277,279]	7	hSpCas9	negative selection	8332075
152352711	152352734	4	-	27260156	PANC0813	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.3578105088869524	[1148]	[1010,1153,974,1065]	-5	hSpCas9	negative selection	8332076
152352699	152352722	4	+	27260156	PANC0813	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.380537215775979	[1460]	[2467,2056,2480,1964]	6	hSpCas9	negative selection	8332077
152382296	152382319	4	-	27260156	PANC0813	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.3612247422473801	[920]	[1058,738,761,827]	-5	hSpCas9	negative selection	8396339
152330759	152330782	4	-	27260156	PANC0813	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.7569716744323863	[426]	[309,300,299,277]	-8	hSpCas9	negative selection	8396340
152330731	152330754	4	-	27260156	PANC0813	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.5297909032153565	[53]	[26,123,26,176]	8	hSpCas9	negative selection	8396341
152382184	152382207	4	+	27260156	RDES	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.3290912603208749	[222]	[248,298,418,335]	5	hSpCas9	negative selection	8453326
152352711	152352734	4	-	27260156	RDES	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.04181724279644872	[1148]	[1055,1360,1398,1703]	0	hSpCas9	negative selection	8453327
152352699	152352722	4	+	27260156	RDES	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.49152161968240704	[1460]	[2079,2349,2379,2672]	7	hSpCas9	negative selection	8453328
152382296	152382319	4	-	27260156	RDES	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.4055948949239917	[920]	[754,750,840,847]	-6	hSpCas9	negative selection	8517590
152330759	152330782	4	-	27260156	RDES	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.40007524015170226	[426]	[272,433,395,393]	-6	hSpCas9	negative selection	8517591
152330731	152330754	4	-	27260156	RDES	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.6955026202041426	[53]	[19,31,39,69]	-8	hSpCas9	negative selection	8517592
152382184	152382207	4	+	27260156	PC3	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	-0.11313969333425922	[222]	[122,228,423,143]	-3	hSpCas9	negative selection	8574577
152352711	152352734	4	-	27260156	PC3	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.2649263495709413	[1148]	[647,714,1539,1197]	-5	hSpCas9	negative selection	8574578
152352699	152352722	4	+	27260156	PC3	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.14442459721101208	[1460]	[1097,1552,2788,1511]	3	hSpCas9	negative selection	8574579
152382296	152382319	4	-	27260156	PC3	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.3228544901416732	[920]	[551,727,1094,694]	-6	hSpCas9	negative selection	8638841
152330759	152330782	4	-	27260156	PC3	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.12620945825649577	[426]	[155,444,746,425]	-3	hSpCas9	negative selection	8638842
152330731	152330754	4	-	27260156	PC3	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.5370160414076564	[53]	[5,110,5,19]	-8	hSpCas9	negative selection	8638843
152382184	152382207	4	+	27260156	PATU8988T	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.5275372405004312	[222]	[228,441,216,372]	8	hSpCas9	negative selection	8695828
152352711	152352734	4	-	27260156	PATU8988T	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.0675565466657404	[1148]	[892,1094,978,1293]	-1	hSpCas9	negative selection	8695829
152352699	152352722	4	+	27260156	PATU8988T	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.1592605311146802	[1460]	[1640,1662,1375,1641]	2	hSpCas9	negative selection	8695830
152382296	152382319	4	-	27260156	PATU8988T	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	0.07627589320990269	[920]	[736,1101,848,1093]	1	hSpCas9	negative selection	8760092
152330759	152330782	4	-	27260156	PATU8988T	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.1507129235873908	[426]	[667,522,347,286]	2	hSpCas9	negative selection	8760093
152330731	152330754	4	-	27260156	PATU8988T	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.4394666186658749	[53]	[33,88,28,3]	-6	hSpCas9	negative selection	8760094
152382184	152382207	4	+	27260156	T47D	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.2422258993095362	[222]	[281,276,377,292]	5	hSpCas9	negative selection	8817079
152352711	152352734	4	-	27260156	T47D	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.050801958447336704	[1148]	[1293,1043,1414,1439]	-1	hSpCas9	negative selection	8817080
152352699	152352722	4	+	27260156	T47D	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.22281598916049905	[1460]	[2072,1810,2058,2016]	5	hSpCas9	negative selection	8817081
152382296	152382319	4	-	27260156	T47D	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.12970056810633734	[920]	[883,1026,970,1037]	-3	hSpCas9	negative selection	8881343
152330759	152330782	4	-	27260156	T47D	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.19999879987999955	[426]	[556,545,530,656]	4	hSpCas9	negative selection	8881344
152330731	152330754	4	-	27260156	T47D	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	0.04665655972739868	[53]	[43,77,21,116]	1	hSpCas9	negative selection	8881345
152382184	152382207	4	+	27260156	SU8686	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.5269663769812917	[222]	[310,361,297,290]	8	hSpCas9	negative selection	8938330
152352711	152352734	4	-	27260156	SU8686	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.41257297728560605	[1148]	[710,749,989,1027]	-6	hSpCas9	negative selection	8938331
152352699	152352722	4	+	27260156	SU8686	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.3853580527503595	[1460]	[1494,1851,2017,2310]	6	hSpCas9	negative selection	8938332
152382296	152382319	4	-	27260156	SU8686	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.3958727048833789	[920]	[728,642,699,702]	-6	hSpCas9	negative selection	9002594
152330759	152330782	4	-	27260156	SU8686	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.10999447999737466	[426]	[409,340,395,429]	-2	hSpCas9	negative selection	9002595
152330731	152330754	4	-	27260156	SU8686	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.7778314390811931	[53]	[16,21,71,14]	-8	hSpCas9	negative selection	9002596
152382184	152382207	4	+	27260156	SKES1	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.23862919926900483	[222]	[368,245,173,270]	5	hSpCas9	negative selection	9059581
152352711	152352734	4	-	27260156	SKES1	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.12853424516105916	[1148]	[1127,1369,989,777]	-3	hSpCas9	negative selection	9059582
152352699	152352722	4	+	27260156	SKES1	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.33287055184428915	[1460]	[2227,2000,1693,1514]	7	hSpCas9	negative selection	9059583
152382296	152382319	4	-	27260156	SKES1	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.30174870227968476	[920]	[757,716,806,694]	-6	hSpCas9	negative selection	9123845
152330759	152330782	4	-	27260156	SKES1	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.4259855577740894	[426]	[387,354,235,302]	-7	hSpCas9	negative selection	9123846
152330731	152330754	4	-	27260156	SKES1	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.258154526792556	[53]	[52,41,76,11]	-5	hSpCas9	negative selection	9123847
152382184	152382207	4	+	27260156	TOV112D	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.10754083100153156	[222]	[270,284,265,155]	2	hSpCas9	negative selection	9180832
152352711	152352734	4	-	27260156	TOV112D	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.05261597361538195	[1148]	[1384,1386,939,823]	-1	hSpCas9	negative selection	9180833
152352699	152352722	4	+	27260156	TOV112D	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.22280506441093362	[1460]	[1712,2044,1366,1783]	4	hSpCas9	negative selection	9180834
152382296	152382319	4	-	27260156	TOV112D	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.12039352460778685	[920]	[919,634,1038,754]	-2	hSpCas9	negative selection	9245096
152330759	152330782	4	-	27260156	TOV112D	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.8307851309759279	[426]	[202,381,201,206]	-9	hSpCas9	negative selection	9245097
152330731	152330754	4	-	27260156	TOV112D	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.24303604668560652	[53]	[82,17,66,11]	-5	hSpCas9	negative selection	9245098
152382184	152382207	4	+	27260156	TC71	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.08056585264705474	[222]	[250,238,253,267]	2	hSpCas9	negative selection	9302083
152352711	152352734	4	-	27260156	TC71	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.09039439284194306	[1148]	[1173,1118,1069,1273]	-2	hSpCas9	negative selection	9302084
152352699	152352722	4	+	27260156	TC71	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.10552462523327821	[1460]	[1651,1867,1630,1584]	2	hSpCas9	negative selection	9302085
152382296	152382319	4	-	27260156	TC71	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.14491622675491922	[920]	[805,941,863,966]	-4	hSpCas9	negative selection	9366347
152330759	152330782	4	-	27260156	TC71	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	-0.2056115438698391	[426]	[428,412,413,325]	-5	hSpCas9	negative selection	9366348
152330731	152330754	4	-	27260156	TC71	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.45428262055150226	[53]	[38,46,31,51]	-8	hSpCas9	negative selection	9366349
152382184	152382207	4	+	27260156	TC32	viability	CTTACCCGTCTTCGACAAAAAGG	FBXW7	ENSG00000109670	0.5214246398495854	[222]	[355,142,346,406]	8	hSpCas9	negative selection	9423334
152352711	152352734	4	-	27260156	TC32	viability	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.5313326972239771	[1148]	[703,580,1048,728]	-7	hSpCas9	negative selection	9423335
152352699	152352722	4	+	27260156	TC32	viability	CTCAGTATCAAACCGCTTCTCGG	FBXW7	ENSG00000109670	0.4333432418490071	[1460]	[1781,1745,1864,1959]	7	hSpCas9	negative selection	9423336
152382296	152382319	4	-	27260156	TC32	viability	ACCTACTCTAAACCATGGCTTGG	FBXW7	ENSG00000109670	-0.40531958907054677	[920]	[588,408,930,805]	-6	hSpCas9	negative selection	9487598
152330759	152330782	4	-	27260156	TC32	viability	AGCACAGAATTGATACTAACTGG	FBXW7	ENSG00000109670	0.034209506605580836	[426]	[390,248,598,481]	0	hSpCas9	negative selection	9487599
152330731	152330754	4	-	27260156	TC32	viability	AGGAGAACTCAAATCTCCTAAGG	FBXW7	ENSG00000109670	-0.2447548442571672	[53]	[34,35,80,25]	-4	hSpCas9	negative selection	9487600
152330751	152330774	4	-	27869803	HPAFII	viability after 27 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-3.2667090954658087	[227]	[6,16,NaN]	-9	hSpCas9	negative selection	9587169
152347047	152347070	4	+	27869803	HPAFII	viability after 27 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.6847758131777036	[434]	[42,224,NaN]	-5	hSpCas9	negative selection	9587170
152350085	152350108	4	+	27869803	HPAFII	viability after 27 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.4298477318260313	[330]	[102,150,NaN]	-3	hSpCas9	negative selection	9587171
152352711	152352734	4	-	27869803	HPAFII	viability after 27 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	-0.34416285980297756	[573]	[240,234,NaN]	-3	hSpCas9	negative selection	9587172
152382211	152382234	4	-	27869803	HPAFII	viability after 27 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.7130914789317402	[71]	[9,33,NaN]	-5	hSpCas9	negative selection	9587173
152411716	152411739	4	+	27869803	HPAFII	viability after 27 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.05905080570033988	[201]	[114,106,NaN]	0	hSpCas9	negative selection	9587174
152330751	152330774	4	-	27869803	HPAFII	viability after 15 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-1.0869260231850804	[227]	[168,81,NaN]	-8	hSpCas9	negative selection	9669618
152347047	152347070	4	+	27869803	HPAFII	viability after 15 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.7834649122881318	[434]	[352,220,NaN]	-7	hSpCas9	negative selection	9669619
152350085	152350108	4	+	27869803	HPAFII	viability after 15 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-0.43635341098095126	[330]	[318,227,NaN]	-5	hSpCas9	negative selection	9669620
152352711	152352734	4	-	27869803	HPAFII	viability after 15 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.12622898704102092	[573]	[869,550,NaN]	1	hSpCas9	negative selection	9669621
152382211	152382234	4	-	27869803	HPAFII	viability after 15 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.6048286554633038	[71]	[84,137,NaN]	7	hSpCas9	negative selection	9669622
152411716	152411739	4	+	27869803	HPAFII	viability after 15 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.15435839770716195	[201]	[359,167,NaN]	1	hSpCas9	negative selection	9669623
152330751	152330774	4	-	27869803	ASPC1	viability after 36 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-0.05213780199723017	[385]	[308,71,48]	0	hSpCas9	negative selection	9752067
152347047	152347070	4	+	27869803	ASPC1	viability after 36 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.8326578520475553	[1258]	[371,192,198]	-7	hSpCas9	negative selection	9752068
152350085	152350108	4	+	27869803	ASPC1	viability after 36 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	0.2719917919281204	[649]	[379,454,52]	2	hSpCas9	negative selection	9752069
152352711	152352734	4	-	27869803	ASPC1	viability after 36 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.27618383455924556	[1574]	[651,877,499]	2	hSpCas9	negative selection	9752070
152382211	152382234	4	-	27869803	ASPC1	viability after 36 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	0.42096800935894557	[331]	[197,219,71]	4	hSpCas9	negative selection	9752071
152411716	152411739	4	+	27869803	ASPC1	viability after 36 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.6267659543914594	[499]	[208,217,349]	6	hSpCas9	negative selection	9752072
152330751	152330774	4	-	27869803	PATU8988S	viability after 35 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-4.187647685267442	[406]	[6,10,NaN]	-9	hSpCas9	negative selection	9834516
152347047	152347070	4	+	27869803	PATU8988S	viability after 35 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.764522523966649	[982]	[126,105,NaN]	-8	hSpCas9	negative selection	9834517
152350085	152350108	4	+	27869803	PATU8988S	viability after 35 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.6346665345797164	[731]	[69,119,NaN]	-8	hSpCas9	negative selection	9834518
152352711	152352734	4	-	27869803	PATU8988S	viability after 35 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.8327653139696871	[1289]	[865,984,NaN]	8	hSpCas9	negative selection	9834519
152382211	152382234	4	-	27869803	PATU8988S	viability after 35 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.712692734157895	[414]	[95,107,NaN]	-6	hSpCas9	negative selection	9834520
152411716	152411739	4	+	27869803	PATU8988S	viability after 35 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.7642893950116108	[395]	[225,315,NaN]	7	hSpCas9	negative selection	9834521
152330751	152330774	4	-	27869803	PATU8988S	viability after 31 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-3.56004726812673	[406]	[11,15,NaN]	-9	hSpCas9	negative selection	9916965
152347047	152347070	4	+	27869803	PATU8988S	viability after 31 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.7169613011084932	[982]	[76,172,NaN]	-8	hSpCas9	negative selection	9916966
152350085	152350108	4	+	27869803	PATU8988S	viability after 31 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.635827559283685	[731]	[107,75,NaN]	-8	hSpCas9	negative selection	9916967
152352711	152352734	4	-	27869803	PATU8988S	viability after 31 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.6878967551516055	[1289]	[781,887,NaN]	7	hSpCas9	negative selection	9916968
152382211	152382234	4	-	27869803	PATU8988S	viability after 31 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.3945971403325151	[414]	[124,126,NaN]	-4	hSpCas9	negative selection	9916969
152411716	152411739	4	+	27869803	PATU8988S	viability after 31 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.9409753818560358	[395]	[230,394,NaN]	9	hSpCas9	negative selection	9916970
152330751	152330774	4	-	27869803	HPAFII	viability after 35 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-2.0532552683904157	[227]	[0,57,NaN]	-8	hSpCas9	negative selection	9999414
152347047	152347070	4	+	27869803	HPAFII	viability after 35 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.5488413371777012	[434]	[39,274,NaN]	-3	hSpCas9	negative selection	9999415
152350085	152350108	4	+	27869803	HPAFII	viability after 35 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.3113186954802545	[330]	[51,84,NaN]	-6	hSpCas9	negative selection	9999416
152352711	152352734	4	-	27869803	HPAFII	viability after 35 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.10506734695546172	[573]	[328,293,NaN]	0	hSpCas9	negative selection	9999417
152382211	152382234	4	-	27869803	HPAFII	viability after 35 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.6981391838971669	[71]	[13,31,NaN]	-4	hSpCas9	negative selection	9999418
152411716	152411739	4	+	27869803	HPAFII	viability after 35 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	-0.8581155223752293	[201]	[62,48,NaN]	-5	hSpCas9	negative selection	9999419
152330751	152330774	4	-	27869803	HPAFII	viability after 31 days	ATTGATACTAACTGGAGGCGAGG	FBXW7	ENSG00000109670	-2.7247246951932165	[227]	[4,34,NaN]	-8	hSpCas9	negative selection	10081863
152347047	152347070	4	+	27869803	HPAFII	viability after 31 days	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.8673350507893235	[434]	[73,198,NaN]	-5	hSpCas9	negative selection	10081864
152350085	152350108	4	+	27869803	HPAFII	viability after 31 days	AAGAGCGGACCTCAGAACCATGG	FBXW7	ENSG00000109670	-1.2556179570331303	[330]	[50,106,NaN]	-6	hSpCas9	negative selection	10081865
152352711	152352734	4	-	27869803	HPAFII	viability after 31 days	TGTATGTGTGTCCCGAGAAGCGG	FBXW7	ENSG00000109670	0.2834106912914056	[573]	[426,353,NaN]	2	hSpCas9	negative selection	10081866
152382211	152382234	4	-	27869803	HPAFII	viability after 31 days	AGCATTAGCATCATTGCCCAAGG	FBXW7	ENSG00000109670	-0.5109135266817011	[71]	[13,43,NaN]	-3	hSpCas9	negative selection	10081867
152411716	152411739	4	+	27869803	HPAFII	viability after 31 days	CATCTACCTGGCTTGAGGAAGGG	FBXW7	ENSG00000109670	0.07127584093780634	[201]	[87,152,NaN]	0	hSpCas9	negative selection	10081868
152328358	152328381	4	-	28162770	P31FUJ	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	0.8809235316190266	[316]	[685]	8	hSpCas9	negative selection	10156310
152326111	152326134	4	-	28162770	P31FUJ	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.6865471355973829	[514]	[973]	7	hSpCas9	negative selection	10156311
152328219	152328242	4	+	28162770	P31FUJ	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	1.0408976099767844	[145]	[352]	9	hSpCas9	negative selection	10156312
152326186	152326209	4	+	28162770	P31FUJ	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	0.6958590138653591	[227]	[433]	7	hSpCas9	negative selection	10156313
152347006	152347029	4	-	28162770	P31FUJ	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.604723098628516	[168]	[301]	7	hSpCas9	negative selection	10156314
152332596	152332619	4	-	28162770	P31FUJ	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	0.9760118104215287	[121]	[281]	9	hSpCas9	negative selection	10156315
152326033	152326056	4	-	28162770	P31FUJ	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	1.449362455332142	[109]	[352]	9	hSpCas9	negative selection	10156316
152347047	152347070	4	+	28162770	P31FUJ	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	1.2782819823355	[413]	[1179]	9	hSpCas9	negative selection	10156317
152328288	152328311	4	-	28162770	P31FUJ	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	0.6048413397209979	[201]	[360]	7	hSpCas9	negative selection	10156318
152328358	152328381	4	-	28162770	TF1	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10325676
152326111	152326134	4	-	28162770	TF1	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10325677
152328219	152328242	4	+	28162770	TF1	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10325678
152326186	152326209	4	+	28162770	TF1	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10325679
152347006	152347029	4	-	28162770	TF1	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10325680
152332596	152332619	4	-	28162770	TF1	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10325681
152326033	152326056	4	-	28162770	TF1	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10325682
152347047	152347070	4	+	28162770	TF1	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10325683
152328288	152328311	4	-	28162770	TF1	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10325684
152328358	152328381	4	-	28162770	SKM1	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.14600412114722644	[86]	[138]	-1	hSpCas9	negative selection	10495042
152326111	152326134	4	-	28162770	SKM1	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.15555779516220736	[108]	[172]	-1	hSpCas9	negative selection	10495043
152328219	152328242	4	+	28162770	SKM1	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	2.0321474355145397	[25]	[187]	9	hSpCas9	negative selection	10495044
152326186	152326209	4	+	28162770	SKM1	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-1.566744642779931	[61]	[36]	-8	hSpCas9	negative selection	10495045
152347006	152347029	4	-	28162770	SKM1	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.05246741989413554	[53]	[98]	0	hSpCas9	negative selection	10495046
152332596	152332619	4	-	28162770	SKM1	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	1.1559719956479957	[32]	[129]	9	hSpCas9	negative selection	10495047
152326033	152326056	4	-	28162770	SKM1	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-0.39750386949409555	[37]	[50]	-3	hSpCas9	negative selection	10495048
152347047	152347070	4	+	28162770	SKM1	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.6176978554911072	[86]	[235]	6	hSpCas9	negative selection	10495049
152328288	152328311	4	-	28162770	SKM1	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-1.5382087320214142	[45]	[27]	-7	hSpCas9	negative selection	10495050
152328358	152328381	4	-	28162770	SKM1	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.14600412114722644	[86]	[138]	-1	hSpCas9	negative selection	10664408
152326111	152326134	4	-	28162770	SKM1	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.15555779516220736	[108]	[172]	-1	hSpCas9	negative selection	10664409
152328219	152328242	4	+	28162770	SKM1	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	2.0321474355145397	[25]	[187]	9	hSpCas9	negative selection	10664410
152326186	152326209	4	+	28162770	SKM1	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-1.566744642779931	[61]	[36]	-8	hSpCas9	negative selection	10664411
152347006	152347029	4	-	28162770	SKM1	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.05246741989413554	[53]	[98]	0	hSpCas9	negative selection	10664412
152332596	152332619	4	-	28162770	SKM1	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	1.1559719956479957	[32]	[129]	9	hSpCas9	negative selection	10664413
152326033	152326056	4	-	28162770	SKM1	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-0.39750386949409555	[37]	[50]	-3	hSpCas9	negative selection	10664414
152347047	152347070	4	+	28162770	SKM1	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.6176978554911072	[86]	[235]	6	hSpCas9	negative selection	10664415
152328288	152328311	4	-	28162770	SKM1	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-1.5382087320214142	[45]	[27]	-7	hSpCas9	negative selection	10664416
152328358	152328381	4	-	28162770	PL21	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	0.9005793326304123	[271]	[220]	7	hSpCas9	negative selection	10833774
152326111	152326134	4	-	28162770	PL21	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	1.0573390140902963	[381]	[345]	8	hSpCas9	negative selection	10833775
152328219	152328242	4	+	28162770	PL21	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	0.27637520031640533	[128]	[67]	2	hSpCas9	negative selection	10833776
152326186	152326209	4	+	28162770	PL21	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	0.54362385274313	[185]	[117]	5	hSpCas9	negative selection	10833777
152347006	152347029	4	-	28162770	PL21	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-0.5871310615249514	[213]	[61]	-4	hSpCas9	negative selection	10833778
152332596	152332619	4	-	28162770	PL21	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	1.3971764615488738	[163]	[187]	9	hSpCas9	negative selection	10833779
152326033	152326056	4	-	28162770	PL21	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-0.5117349987140556	[94]	[28]	-4	hSpCas9	negative selection	10833780
152347047	152347070	4	+	28162770	PL21	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.7812447073433327	[307]	[77]	-5	hSpCas9	negative selection	10833781
152328288	152328311	4	-	28162770	PL21	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-0.5055750456924462	[136]	[41]	-4	hSpCas9	negative selection	10833782
152328358	152328381	4	-	28162770	P31FUJ	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	0.8809235316190266	[316]	[685]	8	hSpCas9	negative selection	11003140
152326111	152326134	4	-	28162770	P31FUJ	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.6865471355973829	[514]	[973]	7	hSpCas9	negative selection	11003141
152328219	152328242	4	+	28162770	P31FUJ	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	1.0408976099767844	[145]	[352]	9	hSpCas9	negative selection	11003142
152326186	152326209	4	+	28162770	P31FUJ	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	0.6958590138653591	[227]	[433]	7	hSpCas9	negative selection	11003143
152347006	152347029	4	-	28162770	P31FUJ	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.604723098628516	[168]	[301]	7	hSpCas9	negative selection	11003144
152332596	152332619	4	-	28162770	P31FUJ	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	0.9760118104215287	[121]	[281]	9	hSpCas9	negative selection	11003145
152326033	152326056	4	-	28162770	P31FUJ	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	1.449362455332142	[109]	[352]	9	hSpCas9	negative selection	11003146
152347047	152347070	4	+	28162770	P31FUJ	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	1.2782819823355	[413]	[1179]	9	hSpCas9	negative selection	11003147
152328288	152328311	4	-	28162770	P31FUJ	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	0.6048413397209979	[201]	[360]	7	hSpCas9	negative selection	11003148
152328358	152328381	4	-	28162770	OCIAML5	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.582459511106717	[145]	[175]	-4	hSpCas9	negative selection	11172506
152326111	152326134	4	-	28162770	OCIAML5	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.5206385042359076	[332]	[418]	-4	hSpCas9	negative selection	11172507
152328219	152328242	4	+	28162770	OCIAML5	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-2.0023092064446097	[90]	[40]	-8	hSpCas9	negative selection	11172508
152326186	152326209	4	+	28162770	OCIAML5	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-0.7076766615288221	[94]	[104]	-5	hSpCas9	negative selection	11172509
152347006	152347029	4	-	28162770	OCIAML5	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.4739197405977188	[70]	[177]	4	hSpCas9	negative selection	11172510
152332596	152332619	4	-	28162770	OCIAML5	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	-1.1181414310178417	[94]	[78]	-6	hSpCas9	negative selection	11172511
152326033	152326056	4	-	28162770	OCIAML5	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-1.8278190246173196	[58]	[29]	-7	hSpCas9	negative selection	11172512
152347047	152347070	4	+	28162770	OCIAML5	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.17097542145256572	[178]	[286]	-1	hSpCas9	negative selection	11172513
152328288	152328311	4	-	28162770	OCIAML5	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-2.57585677628247	[108]	[32]	-8	hSpCas9	negative selection	11172514
152328358	152328381	4	-	28162770	EOL1	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.026908376471428297	[525]	[271]	0	hSpCas9	negative selection	11341872
152326111	152326134	4	-	28162770	EOL1	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.3212067415345238	[473]	[311]	3	hSpCas9	negative selection	11341873
152328219	152328242	4	+	28162770	EOL1	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-1.3250661185009376	[213]	[44]	-7	hSpCas9	negative selection	11341874
152326186	152326209	4	+	28162770	EOL1	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-1.3891127073332272	[347]	[69]	-7	hSpCas9	negative selection	11341875
152347006	152347029	4	-	28162770	EOL1	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-1.1566483112774462	[401]	[94]	-6	hSpCas9	negative selection	11341876
152332596	152332619	4	-	28162770	EOL1	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	-0.5779525689586488	[288]	[101]	-4	hSpCas9	negative selection	11341877
152326033	152326056	4	-	28162770	EOL1	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-4.006189565992352	[121]	[3]	-9	hSpCas9	negative selection	11341878
152347047	152347070	4	+	28162770	EOL1	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-1.0089568166425589	[423]	[110]	-6	hSpCas9	negative selection	11341879
152328288	152328311	4	-	28162770	EOL1	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-2.348470722835881	[144]	[14]	-8	hSpCas9	negative selection	11341880
152328358	152328381	4	-	28162770	MOLM13	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.8069323208970027	[466]	[192]	-4	hSpCas9	negative selection	11511238
152326111	152326134	4	-	28162770	MOLM13	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.6485695950428039	[489]	[225]	-4	hSpCas9	negative selection	11511239
152328219	152328242	4	+	28162770	MOLM13	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-0.6732866814161156	[235]	[106]	-4	hSpCas9	negative selection	11511240
152326186	152326209	4	+	28162770	MOLM13	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-0.60535960048606	[302]	[143]	-3	hSpCas9	negative selection	11511241
152347006	152347029	4	-	28162770	MOLM13	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-0.6922451167049243	[256]	[114]	-4	hSpCas9	negative selection	11511242
152332596	152332619	4	-	28162770	MOLM13	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	-1.4065797363715624	[252]	[68]	-6	hSpCas9	negative selection	11511243
152326033	152326056	4	-	28162770	MOLM13	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-2.204535960426917	[152]	[23]	-7	hSpCas9	negative selection	11511244
152347047	152347070	4	+	28162770	MOLM13	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.7918920464941274	[442]	[184]	-4	hSpCas9	negative selection	11511245
152328288	152328311	4	-	28162770	MOLM13	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-1.9055690139828656	[227]	[43]	-7	hSpCas9	negative selection	11511246
152328358	152328381	4	-	28162770	HEL	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-1.6752312493183221	[363]	[72]	-7	hSpCas9	negative selection	11680604
152326111	152326134	4	-	28162770	HEL	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.9541222519673681	[486]	[160]	-5	hSpCas9	negative selection	11680605
152328219	152328242	4	+	28162770	HEL	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-2.6630695975237284	[177]	[17]	-8	hSpCas9	negative selection	11680606
152326186	152326209	4	+	28162770	HEL	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-2.566714533628593	[258]	[27]	-8	hSpCas9	negative selection	11680607
152347006	152347029	4	-	28162770	HEL	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-1.6974900796299492	[237]	[46]	-7	hSpCas9	negative selection	11680608
152332596	152332619	4	-	28162770	HEL	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	-1.6721345053530547	[203]	[40]	-7	hSpCas9	negative selection	11680609
152326033	152326056	4	-	28162770	HEL	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-2.6527170515258143	[107]	[10]	-8	hSpCas9	negative selection	11680610
152347047	152347070	4	+	28162770	HEL	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-3.1646160900572466	[377]	[26]	-9	hSpCas9	negative selection	11680611
152328288	152328311	4	-	28162770	HEL	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-3.862789201226395	[158]	[6]	-9	hSpCas9	negative selection	11680612
152328358	152328381	4	-	28162770	MV411	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	0.6961343614128506	[232]	[317]	6	hSpCas9	negative selection	11849970
152326111	152326134	4	-	28162770	MV411	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.06386437833685554	[384]	[338]	0	hSpCas9	negative selection	11849971
152328219	152328242	4	+	28162770	MV411	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-0.23289140874778747	[112]	[80]	-2	hSpCas9	negative selection	11849972
152326186	152326209	4	+	28162770	MV411	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	0.6201899047478201	[250]	[324]	5	hSpCas9	negative selection	11849973
152347006	152347029	4	-	28162770	MV411	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.9092688148882021	[200]	[317]	7	hSpCas9	negative selection	11849974
152332596	152332619	4	-	28162770	MV411	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	1.0822151683057515	[133]	[238]	8	hSpCas9	negative selection	11849975
152326033	152326056	4	-	28162770	MV411	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-1.929440211301304	[103]	[22]	-8	hSpCas9	negative selection	11849976
152347047	152347070	4	+	28162770	MV411	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.37063661558044736	[257]	[280]	3	hSpCas9	negative selection	11849977
152328288	152328311	4	-	28162770	MV411	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-0.8872119759120065	[100]	[45]	-6	hSpCas9	negative selection	11849978
152328358	152328381	4	-	28162770	MONOMAC1	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	0.37765731820777526	[187]	[279]	4	hSpCas9	negative selection	12019336
152326111	152326134	4	-	28162770	MONOMAC1	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.33165743401485726	[243]	[351]	3	hSpCas9	negative selection	12019337
152328219	152328242	4	+	28162770	MONOMAC1	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	0.0759816473468623	[71]	[86]	0	hSpCas9	negative selection	12019338
152326186	152326209	4	+	28162770	MONOMAC1	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-0.373914609143633	[129]	[114]	-3	hSpCas9	negative selection	12019339
152347006	152347029	4	-	28162770	MONOMAC1	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.2852399896870386	[130]	[182]	3	hSpCas9	negative selection	12019340
152332596	152332619	4	-	28162770	MONOMAC1	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	0.9125876441149445	[94]	[204]	8	hSpCas9	negative selection	12019341
152326033	152326056	4	-	28162770	MONOMAC1	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-0.4738770524183781	[62]	[51]	-4	hSpCas9	negative selection	12019342
152347047	152347070	4	+	28162770	MONOMAC1	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	0.8885388846465204	[179]	[381]	7	hSpCas9	negative selection	12019343
152328288	152328311	4	-	28162770	MONOMAC1	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	0.9098783568569582	[77]	[167]	8	hSpCas9	negative selection	12019344
152328358	152328381	4	-	28162770	OCIAML2	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	-0.8994731240460355	[69]	[207]	-6	hSpCas9	negative selection	12188702
152326111	152326134	4	-	28162770	OCIAML2	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	-0.08692553276810888	[63]	[333]	0	hSpCas9	negative selection	12188703
152328219	152328242	4	+	28162770	OCIAML2	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	-0.9058452064586355	[23]	[70]	-6	hSpCas9	negative selection	12188704
152326186	152326209	4	+	28162770	OCIAML2	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	-1.0199684162325962	[44]	[122]	-6	hSpCas9	negative selection	12188705
152347006	152347029	4	-	28162770	OCIAML2	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	-0.5923083818304135	[33]	[124]	-4	hSpCas9	negative selection	12188706
152332596	152332619	4	-	28162770	OCIAML2	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	0.2027706401465788	[28]	[184]	2	hSpCas9	negative selection	12188707
152326033	152326056	4	-	28162770	OCIAML2	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	-3.4706298252421615	[21]	[10]	-9	hSpCas9	negative selection	12188708
152347047	152347070	4	+	28162770	OCIAML2	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	-0.31946575190851045	[42]	[190]	-3	hSpCas9	negative selection	12188709
152328288	152328311	4	-	28162770	OCIAML2	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-0.968129484712978	[23]	[67]	-6	hSpCas9	negative selection	12188710
152328358	152328381	4	-	28162770	OCIAML3	viability	ACATTAGTGGGACATACAGGTGG	FBXW7	ENSG00000109670	0.7582941036067179	[93]	[479]	6	hSpCas9	negative selection	12358068
152326111	152326134	4	-	28162770	OCIAML3	viability	GTGTTCAATATGATGGCAGGAGG	FBXW7	ENSG00000109670	0.28365681675178456	[122]	[451]	2	hSpCas9	negative selection	12358069
152328219	152328242	4	+	28162770	OCIAML3	viability	AAGATGCATACAACGCACAGTGG	FBXW7	ENSG00000109670	0.017427071758184143	[35]	[109]	0	hSpCas9	negative selection	12358070
152326186	152326209	4	+	28162770	OCIAML3	viability	AATATCCCAAACCCTAAGAGTGG	FBXW7	ENSG00000109670	1.0140384735100343	[61]	[377]	8	hSpCas9	negative selection	12358071
152347006	152347029	4	-	28162770	OCIAML3	viability	GGGGACCTCAGAGCAGCCAATGG	FBXW7	ENSG00000109670	0.9365070763746168	[35]	[207]	7	hSpCas9	negative selection	12358072
152332596	152332619	4	-	28162770	OCIAML3	viability	GAGAGAGAAATGCAAAGAAGAGG	FBXW7	ENSG00000109670	0.606131974165157	[41]	[192]	5	hSpCas9	negative selection	12358073
152326033	152326056	4	-	28162770	OCIAML3	viability	CCTGTCTACACACGTTGCAGGGG	FBXW7	ENSG00000109670	0.036042749925530915	[20]	[64]	0	hSpCas9	negative selection	12358074
152347047	152347070	4	+	28162770	OCIAML3	viability	TGAACATGGTACAAGCCCAGTGG	FBXW7	ENSG00000109670	1.2779370761764315	[77]	[570]	9	hSpCas9	negative selection	12358075
152328288	152328311	4	-	28162770	OCIAML3	viability	CAGATCGGACACTCAAAGTGTGG	FBXW7	ENSG00000109670	-0.10046816736660169	[37]	[106]	-1	hSpCas9	negative selection	12358076