Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2210
• Symbol:FCGR1B
• Description:Fc fragment of IgG receptor Ib

DataSource: http://genomecrispr.dkfz.de/#!/results/FCGR1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
121087418	121087441	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGAGTCCAACTTACCCCAAAGG	FCGR1B	ENSG00000198019	0.37785228207689436	[2,2]	[1,3]	7	hSpCas9	positive selection	2988331
121087418	121087441	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGAGTCCAACTTACCCCAAAGG	FCGR1B	ENSG00000198019	-0.527514591551076	[2,2]	[1,0]	-7	hSpCas9	positive selection	3056189
121087418	121087441	1	-	26780180	HT29	viability (Avana library 4 designs)	CTGAGTCCAACTTACCCCAAAGG	FCGR1B	ENSG00000198019	2.82439155389766	[]	[]	8	hSpCas9	negative selection	3425236
121087418	121087441	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGAGTCCAACTTACCCCAAAGG	FCGR1B	ENSG00000198019	-5.04722347448386	[]	[]	-5	hSpCas9	negative selection	3507265
121087418	121087441	1	-	26780180	A375	viability (Avana lentiGuide)	CTGAGTCCAACTTACCCCAAAGG	FCGR1B	ENSG00000198019	12.9327338793329	[]	[]	7	hSpCas9	negative selection	3615924
121087418	121087441	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGAGTCCAACTTACCCCAAAGG	FCGR1B	ENSG00000198019	-0.49510355811394124	[4]	[3,1]	-6	hSpCas9	positive selection	3724583
121087418	121087441	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGAGTCCAACTTACCCCAAAGG	FCGR1B	ENSG00000198019	-1.4273915338688348	[4]	[1,0]	-9	hSpCas9	positive selection	3833190
121087423	121087446	1	+	27661255	K562	viability	GGGGTAAGTTGGACTCAGAGGGG	FCGR1B	ENSG00000198019	0.1274925604359295	[960,1003]	[928,794]	4	dCas9-KRAB	negative selection	5479922