Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:257019
• Symbol:FRMD3
• Description:FERM domain containing 3

DataSource: http://genomecrispr.dkfz.de/#!/results/FRMD3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
83248052	83248075	9	+	26472758	Jiyoye	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	6.021885225621081	[0]	[48]	9	hSpCas9	negative selection	59919
83248489	83248512	9	+	26472758	Jiyoye	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	-0.5710640997553159	[328]	[166]	-4	hSpCas9	negative selection	59920
83248454	83248477	9	-	26472758	Jiyoye	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-5.903891720749722	[396]	[4]	-9	hSpCas9	negative selection	59921
83248326	83248349	9	+	26472758	Jiyoye	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.3287487345490572	[188]	[178]	2	hSpCas9	negative selection	59922
83248097	83248120	9	+	26472758	Jiyoye	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.18110730202602737	[130]	[111]	1	hSpCas9	negative selection	59923
83248368	83248391	9	+	26472758	Jiyoye	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.6850285020512124	[112]	[136]	5	hSpCas9	negative selection	59924
83248202	83248225	9	-	26472758	Jiyoye	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-1.2708965236067644	[127]	[39]	-7	hSpCas9	negative selection	59925
83248182	83248205	9	-	26472758	Jiyoye	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.3708029918409116	[240]	[234]	2	hSpCas9	negative selection	59926
83248443	83248466	9	+	26472758	Jiyoye	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	-0.25307524651951974	[176]	[111]	-2	hSpCas9	negative selection	59927
83248175	83248198	9	+	26472758	Jiyoye	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	4.494638222756212	[0]	[16]	9	hSpCas9	negative selection	59928
83248052	83248075	9	+	26472758	KBM7	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	-0.11665640539958355	[157,138]	[105,26]	-1	hSpCas9	negative selection	251037
83248489	83248512	9	+	26472758	KBM7	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.5831084671531082	[1041,938]	[529,846]	6	hSpCas9	negative selection	251038
83248454	83248477	9	-	26472758	KBM7	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-2.6814848655245735	[1129,1033]	[91,67]	-9	hSpCas9	negative selection	251039
83248326	83248349	9	+	26472758	KBM7	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.8672054391772669	[922,831]	[897,621]	8	hSpCas9	negative selection	251040
83248097	83248120	9	+	26472758	KBM7	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	-0.0021558394309217493	[554,453]	[318,160]	0	hSpCas9	negative selection	251041
83248368	83248391	9	+	26472758	KBM7	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.572599771113201	[495,441]	[466,202]	6	hSpCas9	negative selection	251042
83248202	83248225	9	-	26472758	KBM7	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.29180755424098903	[232,149]	[66,76]	-3	hSpCas9	negative selection	251043
83248182	83248205	9	-	26472758	KBM7	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.3695274670944442	[903,1308]	[483,347]	-3	hSpCas9	negative selection	251044
83248443	83248466	9	+	26472758	KBM7	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.4280506610131558	[559,429]	[367,258]	4	hSpCas9	negative selection	251045
83248175	83248198	9	+	26472758	KBM7	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	1.5617874922422073	[35,40]	[52,54]	9	hSpCas9	negative selection	251046
83248052	83248075	9	+	26472758	Raji	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	1.3215083407264467	[49]	[28]	9	hSpCas9	negative selection	442155
83248489	83248512	9	+	26472758	Raji	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.011381715496245781	[465]	[108]	0	hSpCas9	negative selection	442156
83248454	83248477	9	-	26472758	Raji	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-1.3774148034221247	[458]	[40]	-7	hSpCas9	negative selection	442157
83248326	83248349	9	+	26472758	Raji	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.0923082149115011	[480]	[118]	0	hSpCas9	negative selection	442158
83248097	83248120	9	+	26472758	Raji	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	-0.10762935559725095	[259]	[55]	-1	hSpCas9	negative selection	442159
83248368	83248391	9	+	26472758	Raji	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.9374585339312871	[143]	[63]	8	hSpCas9	negative selection	442160
83248202	83248225	9	-	26472758	Raji	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.5055933415171534	[103]	[16]	-4	hSpCas9	negative selection	442161
83248182	83248205	9	-	26472758	Raji	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.5417863595193744	[443]	[149]	5	hSpCas9	negative selection	442162
83248443	83248466	9	+	26472758	Raji	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.3445597732863674	[318]	[93]	3	hSpCas9	negative selection	442163
83248175	83248198	9	+	26472758	Raji	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	-0.4533314191008797	[58]	[9]	-4	hSpCas9	negative selection	442164
83248052	83248075	9	+	26472758	K562	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	1.5553478236045521	[157]	[391]	9	hSpCas9	negative selection	633273
83248489	83248512	9	+	26472758	K562	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.9408025110560261	[821]	[1331]	7	hSpCas9	negative selection	633274
83248454	83248477	9	-	26472758	K562	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-3.812698243131914	[1081]	[64]	-9	hSpCas9	negative selection	633275
83248326	83248349	9	+	26472758	K562	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.7681597188690976	[1050]	[1510]	6	hSpCas9	negative selection	633276
83248097	83248120	9	+	26472758	K562	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.21000869688061555	[296]	[289]	1	hSpCas9	negative selection	633277
83248368	83248391	9	+	26472758	K562	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.8766869431659596	[439]	[681]	7	hSpCas9	negative selection	633278
83248202	83248225	9	-	26472758	K562	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.04789060054286043	[228]	[186]	0	hSpCas9	negative selection	633279
83248182	83248205	9	-	26472758	K562	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	1.2568682144999408	[749]	[1512]	9	hSpCas9	negative selection	633280
83248443	83248466	9	+	26472758	K562	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	1.2383781255091475	[358]	[714]	9	hSpCas9	negative selection	633281
83248175	83248198	9	+	26472758	K562	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	1.2279306048778778	[43]	[86]	9	hSpCas9	negative selection	633282
83267011	83267034	9	-	26627737	DLD1	viability	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.40499945693991557	[503]	[228,158,231]	4	hSpCas9	negative selection	843370
83290593	83290616	9	+	26627737	DLD1	viability	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.11748647020308883	[451]	[140,76,164]	-1	hSpCas9	negative selection	843371
83298742	83298765	9	+	26627737	DLD1	viability	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	-0.5990507612548323	[513]	[44,93,168]	-5	hSpCas9	negative selection	843372
83310487	83310510	9	-	26627737	DLD1	viability	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.3409949391981538	[259]	[45,86,60]	-4	hSpCas9	negative selection	843373
83343190	83343213	9	+	26627737	DLD1	viability	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	-0.3091100486866239	[562]	[213,67,140]	-3	hSpCas9	negative selection	843374
83538106	83538129	9	+	26627737	DLD1	viability	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.4684143231811027	[654]	[18,288,142]	-5	hSpCas9	negative selection	843375
83267011	83267034	9	-	26627737	GBM cells	viability after 5 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.2789342011286297	[387]	[172,169]	-4	hSpCas9	negative selection	925685
83290593	83290616	9	+	26627737	GBM cells	viability after 5 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.257994968190514	[321]	[204,207]	4	hSpCas9	negative selection	925686
83298742	83298765	9	+	26627737	GBM cells	viability after 5 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	-0.07334113463141018	[205]	[145,63]	-1	hSpCas9	negative selection	925687
83310487	83310510	9	-	26627737	GBM cells	viability after 5 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.13395075901994102	[221]	[116,99]	-2	hSpCas9	negative selection	925688
83343190	83343213	9	+	26627737	GBM cells	viability after 5 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.2424381985798475	[304]	[172,213]	4	hSpCas9	negative selection	925689
83538106	83538129	9	+	26627737	GBM cells	viability after 5 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.2378648585747578	[198]	[68,111]	-4	hSpCas9	negative selection	925690
83267011	83267034	9	-	26627737	GBM cells	viability after 13 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.03564130247477959	[387]	[211,199]	0	hSpCas9	negative selection	1008000
83290593	83290616	9	+	26627737	GBM cells	viability after 13 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.25671699521620733	[321]	[232,188]	3	hSpCas9	negative selection	1008001
83298742	83298765	9	+	26627737	GBM cells	viability after 13 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	-0.5118050963102139	[205]	[100,59]	-6	hSpCas9	negative selection	1008002
83310487	83310510	9	-	26627737	GBM cells	viability after 13 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.43741389430745947	[221]	[126,57]	-5	hSpCas9	negative selection	1008003
83343190	83343213	9	+	26627737	GBM cells	viability after 13 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.6217096169624502	[304]	[279,233]	7	hSpCas9	negative selection	1008004
83538106	83538129	9	+	26627737	GBM cells	viability after 13 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.013847854021433459	[198]	[128,88]	0	hSpCas9	negative selection	1008005
83267011	83267034	9	-	26627737	GBM cells	viability after 21 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.05415565384743115	[387]	[233,204]	0	hSpCas9	negative selection	1090315
83290593	83290616	9	+	26627737	GBM cells	viability after 21 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.7879334623555876	[321]	[300,302]	7	hSpCas9	negative selection	1090316
83298742	83298765	9	+	26627737	GBM cells	viability after 21 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.08571894495722082	[205]	[135,102]	0	hSpCas9	negative selection	1090317
83310487	83310510	9	-	26627737	GBM cells	viability after 21 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.17796857198137972	[221]	[103,108]	-2	hSpCas9	negative selection	1090318
83343190	83343213	9	+	26627737	GBM cells	viability after 21 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.671415407604316	[304]	[277,250]	6	hSpCas9	negative selection	1090319
83538106	83538129	9	+	26627737	GBM cells	viability after 21 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.19245360269176015	[198]	[91,96]	-2	hSpCas9	negative selection	1090320
83267011	83267034	9	-	26627737	RPE1	viability after 9 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.530561973948106	[1723]	[167,638]	-4	hSpCas9	negative selection	1172630
83290593	83290616	9	+	26627737	RPE1	viability after 9 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.1492792964603676	[1024]	[215,383]	-1	hSpCas9	negative selection	1172631
83298742	83298765	9	+	26627737	RPE1	viability after 9 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	1.1426868952472073	[309]	[198,233]	7	hSpCas9	negative selection	1172632
83310487	83310510	9	-	26627737	RPE1	viability after 9 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-1.0918962858988837	[604]	[80,98]	-7	hSpCas9	negative selection	1172633
83343190	83343213	9	+	26627737	RPE1	viability after 9 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.040364249197281044	[1081]	[150,602]	0	hSpCas9	negative selection	1172634
83538106	83538129	9	+	26627737	RPE1	viability after 9 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-1.3681714339356832	[1589]	[201,180]	-7	hSpCas9	negative selection	1172635
83267011	83267034	9	-	26627737	RPE1	viability after 12 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.41664079483769945	[1723]	[193,508]	-3	hSpCas9	negative selection	1254945
83290593	83290616	9	+	26627737	RPE1	viability after 12 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.36075122477766125	[1024]	[212,215]	-2	hSpCas9	negative selection	1254946
83298742	83298765	9	+	26627737	RPE1	viability after 12 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	1.38779311776669	[309]	[266,165]	7	hSpCas9	negative selection	1254947
83310487	83310510	9	-	26627737	RPE1	viability after 12 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.9543266845905727	[604]	[62,105]	-6	hSpCas9	negative selection	1254948
83343190	83343213	9	+	26627737	RPE1	viability after 12 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	-0.20953253262053206	[1081]	[162,344]	-1	hSpCas9	negative selection	1254949
83538106	83538129	9	+	26627737	RPE1	viability after 12 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.2548838612343234	[1589]	[374,339]	-2	hSpCas9	negative selection	1254950
83267011	83267034	9	-	26627737	RPE1	viability after 15 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.10301100971965305	[1723]	[226,809]	0	hSpCas9	negative selection	1337260
83290593	83290616	9	+	26627737	RPE1	viability after 15 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.030613445257964722	[1024]	[375,194]	0	hSpCas9	negative selection	1337261
83298742	83298765	9	+	26627737	RPE1	viability after 15 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.5614998787600226	[309]	[105,151]	3	hSpCas9	negative selection	1337262
83310487	83310510	9	-	26627737	RPE1	viability after 15 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.8505962187002372	[604]	[71,116]	-5	hSpCas9	negative selection	1337263
83343190	83343213	9	+	26627737	RPE1	viability after 15 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	-0.3758537428822801	[1081]	[45,418]	-2	hSpCas9	negative selection	1337264
83538106	83538129	9	+	26627737	RPE1	viability after 15 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.9596608785005889	[1589]	[131,326]	-6	hSpCas9	negative selection	1337265
83267011	83267034	9	-	26627737	RPE1	viability after 18 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.1720429605959306	[1723]	[237,829]	1	hSpCas9	negative selection	1419575
83290593	83290616	9	+	26627737	RPE1	viability after 18 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.4472463093978887	[1024]	[213,190]	-3	hSpCas9	negative selection	1419576
83298742	83298765	9	+	26627737	RPE1	viability after 18 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	1.1442598996918059	[309]	[196,171]	6	hSpCas9	negative selection	1419577
83310487	83310510	9	-	26627737	RPE1	viability after 18 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.6096560856600673	[604]	[106,106]	-4	hSpCas9	negative selection	1419578
83343190	83343213	9	+	26627737	RPE1	viability after 18 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.06631948396458293	[1081]	[297,313]	0	hSpCas9	negative selection	1419579
83538106	83538129	9	+	26627737	RPE1	viability after 18 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.024189430428836145	[1589]	[478,360]	0	hSpCas9	negative selection	1419580
83267011	83267034	9	-	26627737	HeLa	viability after 8 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.19176975828764226	[533]	[254,182,184]	-2	hSpCas9	negative selection	1501890
83290593	83290616	9	+	26627737	HeLa	viability after 8 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.13322412875915904	[501]	[244,124,234]	-1	hSpCas9	negative selection	1501891
83298742	83298765	9	+	26627737	HeLa	viability after 8 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.8419649902214135	[193]	[277,143,65]	7	hSpCas9	negative selection	1501892
83310487	83310510	9	-	26627737	HeLa	viability after 8 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.828991012757416	[157]	[182,136,63]	6	hSpCas9	negative selection	1501893
83343190	83343213	9	+	26627737	HeLa	viability after 8 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.37775537516278107	[388]	[278,250,147]	3	hSpCas9	negative selection	1501894
83538106	83538129	9	+	26627737	HeLa	viability after 8 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.4526399179046881	[312]	[314,241,40]	4	hSpCas9	negative selection	1501895
83267011	83267034	9	-	26627737	HeLa	viability after 12 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.4041821745403128	[533]	[308,344,216]	3	hSpCas9	negative selection	1584205
83290593	83290616	9	+	26627737	HeLa	viability after 12 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.30272772097588174	[501]	[143,259,359]	2	hSpCas9	negative selection	1584206
83298742	83298765	9	+	26627737	HeLa	viability after 12 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.4866506167938538	[193]	[49,151,128]	4	hSpCas9	negative selection	1584207
83310487	83310510	9	-	26627737	HeLa	viability after 12 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.7395561581970868	[157]	[102,107,115]	6	hSpCas9	negative selection	1584208
83343190	83343213	9	+	26627737	HeLa	viability after 12 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.7886648095519201	[388]	[359,225,254]	6	hSpCas9	negative selection	1584209
83538106	83538129	9	+	26627737	HeLa	viability after 12 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.6167465479894791	[312]	[272,190,133]	5	hSpCas9	negative selection	1584210
83267011	83267034	9	-	26627737	HeLa	viability after 15 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.11846842326543233	[533]	[92,201,315]	-1	hSpCas9	negative selection	1666520
83290593	83290616	9	+	26627737	HeLa	viability after 15 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.5828358489096622	[501]	[282,239,402]	5	hSpCas9	negative selection	1666521
83298742	83298765	9	+	26627737	HeLa	viability after 15 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.9264212436336831	[193]	[180,165,98]	7	hSpCas9	negative selection	1666522
83310487	83310510	9	-	26627737	HeLa	viability after 15 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.47797524180344064	[157]	[58,49,165]	4	hSpCas9	negative selection	1666523
83343190	83343213	9	+	26627737	HeLa	viability after 15 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.8253596955878612	[388]	[271,312,254]	6	hSpCas9	negative selection	1666524
83538106	83538129	9	+	26627737	HeLa	viability after 15 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	1.8038026236064262	[312]	[328,708,285]	9	hSpCas9	negative selection	1666525
83267011	83267034	9	-	26627737	HeLa	viability after 18 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.12369610977883455	[533]	[61,165,315]	-1	hSpCas9	negative selection	1748835
83290593	83290616	9	+	26627737	HeLa	viability after 18 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.56021042677169	[501]	[177,201,402]	4	hSpCas9	negative selection	1748836
83298742	83298765	9	+	26627737	HeLa	viability after 18 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.9332882618946665	[193]	[123,135,98]	7	hSpCas9	negative selection	1748837
83310487	83310510	9	-	26627737	HeLa	viability after 18 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.4057595124274209	[157]	[32,38,165]	3	hSpCas9	negative selection	1748838
83343190	83343213	9	+	26627737	HeLa	viability after 18 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.8130412846971108	[388]	[177,258,254]	6	hSpCas9	negative selection	1748839
83538106	83538129	9	+	26627737	HeLa	viability after 18 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	1.7984504480882153	[312]	[215,588,285]	9	hSpCas9	negative selection	1748840
83267011	83267034	9	-	26627737	HCT116	viability after 6 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.2914007117031668	[489]	[138,20]	-2	hSpCas9	negative selection	1831150
83290593	83290616	9	+	26627737	HCT116	viability after 6 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.3519750745012023	[865]	[156,182]	2	hSpCas9	negative selection	1831151
83298742	83298765	9	+	26627737	HCT116	viability after 6 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.8525387625985399	[497]	[355,22]	5	hSpCas9	negative selection	1831152
83310487	83310510	9	-	26627737	HCT116	viability after 6 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.7689327254614398	[177]	[18,14]	-4	hSpCas9	negative selection	1831153
83343190	83343213	9	+	26627737	HCT116	viability after 6 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.5872694394337807	[766]	[175,183]	3	hSpCas9	negative selection	1831154
83538106	83538129	9	+	26627737	HCT116	viability after 6 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	1.0259002859474515	[693]	[352,149]	5	hSpCas9	negative selection	1831155
83267011	83267034	9	-	26627737	HCT116	viability after 8 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.9263064162867034	[651]	[141,209,213]	-8	hSpCas9	negative selection	1913465
83290593	83290616	9	+	26627737	HCT116	viability after 8 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	1.239819311943926	[196]	[321,251,196]	8	hSpCas9	negative selection	1913466
83298742	83298765	9	+	26627737	HCT116	viability after 8 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	1.9104376290319627	[61]	[120,122,140]	9	hSpCas9	negative selection	1913467
83310487	83310510	9	-	26627737	HCT116	viability after 8 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.005245773318027225	[182]	[91,86,121]	0	hSpCas9	negative selection	1913468
83343190	83343213	9	+	26627737	HCT116	viability after 8 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.3603303962378244	[331]	[135,185,378]	4	hSpCas9	negative selection	1913469
83538106	83538129	9	+	26627737	HCT116	viability after 8 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.05210908628872743	[334]	[156,180,234]	0	hSpCas9	negative selection	1913470
83267011	83267034	9	-	26627737	HCT116	viability after 9 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.5020241226319937	[489]	[102,83]	-4	hSpCas9	negative selection	1995780
83290593	83290616	9	+	26627737	HCT116	viability after 9 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.9890886233081466	[865]	[315,571]	6	hSpCas9	negative selection	1995781
83298742	83298765	9	+	26627737	HCT116	viability after 9 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.5177819765065108	[497]	[138,230]	4	hSpCas9	negative selection	1995782
83310487	83310510	9	-	26627737	HCT116	viability after 9 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	1.0029376810010187	[177]	[192,17]	7	hSpCas9	negative selection	1995783
83343190	83343213	9	+	26627737	HCT116	viability after 9 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.5876382268292193	[766]	[204,388]	4	hSpCas9	negative selection	1995784
83538106	83538129	9	+	26627737	HCT116	viability after 9 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.47646773452670044	[693]	[268,248]	3	hSpCas9	negative selection	1995785
83267011	83267034	9	-	26627737	HCT116	viability after 12 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.7008536281196471	[651]	[239,217,171]	-6	hSpCas9	negative selection	2078095
83290593	83290616	9	+	26627737	HCT116	viability after 12 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	1.125916577823173	[196]	[187,301,192]	8	hSpCas9	negative selection	2078096
83298742	83298765	9	+	26627737	HCT116	viability after 12 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	1.3455436244207548	[61]	[28,159,65]	8	hSpCas9	negative selection	2078097
83310487	83310510	9	-	26627737	HCT116	viability after 12 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.08075221824664647	[182]	[55,95,156]	0	hSpCas9	negative selection	2078098
83343190	83343213	9	+	26627737	HCT116	viability after 12 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.34565672053471386	[331]	[297,203,155]	3	hSpCas9	negative selection	2078099
83538106	83538129	9	+	26627737	HCT116	viability after 12 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.15303313910888988	[334]	[101,242,136]	-1	hSpCas9	negative selection	2078100
83267011	83267034	9	-	26627737	HCT116	viability after 15 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.16610536518896013	[651]	[294,330,369]	-2	hSpCas9	negative selection	2160410
83290593	83290616	9	+	26627737	HCT116	viability after 15 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.9840993439372656	[196]	[161,289,211]	8	hSpCas9	negative selection	2160411
83298742	83298765	9	+	26627737	HCT116	viability after 15 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	1.9835315061714154	[61]	[122,134,161]	9	hSpCas9	negative selection	2160412
83310487	83310510	9	-	26627737	HCT116	viability after 15 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.10310501136972616	[182]	[39,106,138]	-1	hSpCas9	negative selection	2160413
83343190	83343213	9	+	26627737	HCT116	viability after 15 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	-0.12369682723812597	[331]	[214,150,163]	-1	hSpCas9	negative selection	2160414
83538106	83538129	9	+	26627737	HCT116	viability after 15 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.41922952772470623	[334]	[386,260,140]	4	hSpCas9	negative selection	2160415
83267011	83267034	9	-	26627737	HCT116	viability after 18 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.4854075163575904	[651]	[206,227,240]	-4	hSpCas9	negative selection	2242725
83290593	83290616	9	+	26627737	HCT116	viability after 18 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	1.1011048173067177	[196]	[213,173,227]	8	hSpCas9	negative selection	2242726
83298742	83298765	9	+	26627737	HCT116	viability after 18 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	1.2386860960324224	[61]	[50,71,89]	8	hSpCas9	negative selection	2242727
83310487	83310510	9	-	26627737	HCT116	viability after 18 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.16785877450069653	[182]	[53,127,114]	1	hSpCas9	negative selection	2242728
83343190	83343213	9	+	26627737	HCT116	viability after 18 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.04138798024053911	[331]	[150,166,177]	0	hSpCas9	negative selection	2242729
83538106	83538129	9	+	26627737	HCT116	viability after 18 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.17347704497245944	[334]	[97,254,66]	-1	hSpCas9	negative selection	2242730
83376015	83376038	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCACCTGCCACCACGCCAGG	FRMD3	ENSG00000172159	3.5563442726279137	[263,282]	[1245,134]	9	dCas9-VP64	positive selection	2389814
83369101	83369124	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGTGGCCGAAG	FRMD3	ENSG00000172159	1.9344952843638512	[112,48]	[123,6]	6	dCas9-VP64	positive selection	2393480
83452878	83452901	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTCTCGCCCTGTCACCCAGG	FRMD3	ENSG00000172159	-0.4763697853295935	[174,209]	[20,39]	-2	dCas9-VP64	positive selection	2393774
83405717	83405740	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCATTGCACTCCAGCCTCGG	FRMD3	ENSG00000172159	-0.7836007518198642	[44,14]	[5,0]	-4	dCas9-VP64	positive selection	2394678
83464816	83464839	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGACCAGCCTGGCGAACATAG	FRMD3	ENSG00000172159	1.2617043151688576	[103,73]	[81,7]	5	dCas9-VP64	positive selection	2414893
83467897	83467920	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTGCATCTTAATATCCAGCAGG	FRMD3	ENSG00000172159	-2.0102855616552553	[76,94]	[4,3]	-9	dCas9-VP64	positive selection	2415273
83467827	83467850	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCACAGTAAATAGGTTGATGG	FRMD3	ENSG00000172159	-1.442294859632093	[160,182]	[9,16]	-8	dCas9-VP64	positive selection	2415274
83467882	83467905	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTAATTGTTCAAGAACCTGCTGG	FRMD3	ENSG00000172159	-0.2803474034703983	[241,592]	[36,117]	-1	dCas9-VP64	positive selection	2415275
83332134	83332157	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGATCAGTTAGATTTTGCTGAGG	FRMD3	ENSG00000172159	3.947786221698001	[311,41]	[1143,2]	9	dCas9-VP64	positive selection	2415276
83332060	83332083	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCTGCTCTGTGCCCACCAGAGG	FRMD3	ENSG00000172159	-0.5569640519178997	[156,54]	[21,7]	-3	dCas9-VP64	positive selection	2415277
83332094	83332117	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGTGGCTTAGAGCAAGAAAGG	FRMD3	ENSG00000172159	-1.6505523642416569	[443,165]	[3,38]	-8	dCas9-VP64	positive selection	2415278
83267425	83267448	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATGATGAGGCATTTGGACAGGG	FRMD3	ENSG00000172159	-0.13857483634606327	[47,519]	[3,114]	0	dCas9-VP64	positive selection	2415279
83267403	83267426	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTCCTCTGTTTTGGTCCGGAAGG	FRMD3	ENSG00000172159	-1.0434681854039136	[46,195]	[18,5]	-6	dCas9-VP64	positive selection	2415280
83267449	83267472	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGGGGACATTTGATTCTTAGG	FRMD3	ENSG00000172159	-0.8550095521132595	[204,164]	[30,11]	-5	dCas9-VP64	positive selection	2415281
83269677	83269700	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTCTCCCAGGCTAG	FRMD3	ENSG00000172159	-0.22926698104333687	[120,197]	[15,43]	-1	dCas9-VP64	positive selection	2418641
83273182	83273205	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAATAGAAAAGGGGGAAATGTGG	FRMD3	ENSG00000172159	-0.5261836086397467	[77,118]	[9,19]	-3	dCas9-VP64	positive selection	2419290
83369470	83369493	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAAGAG	FRMD3	ENSG00000172159	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422206
83309286	83309309	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACACACACACACACACACAGTGG	FRMD3	ENSG00000172159	0.19128589643959537	[429,108]	[111,17]	0	dCas9-VP64	positive selection	2424269
83476288	83476311	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACCTGG	FRMD3	ENSG00000172159	0.915813201608152	[93,47]	[29,27]	4	dCas9-VP64	positive selection	2442490
83421976	83421999	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGGAGGCAGAGGCAAG	FRMD3	ENSG00000172159	1.3055372672802243	[104,28]	[48,21]	5	dCas9-VP64	positive selection	2470005
83538530	83538553	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCGTCGCGAGCCCGCCGGGGG	FRMD3	ENSG00000172159	2.279345177256146	[153,37]	[35,171]	7	dCas9-VP64	positive selection	2471387
83538507	83538530	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCAGGCTCTGGGCGTCCTCGG	FRMD3	ENSG00000172159	-1.3536947475896366	[394,616]	[40,45]	-7	dCas9-VP64	positive selection	2471388
83376015	83376038	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCACCTGCCACCACGCCAGG	FRMD3	ENSG00000172159	0.46315742416717276	[258,245]	[121,105]	3	dCas9-VP64	positive selection	2485069
83369101	83369124	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGTGGCCGAAG	FRMD3	ENSG00000172159	2.4580893434569377	[23,25]	[9,77]	9	dCas9-VP64	positive selection	2488735
83452878	83452901	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTCTCGCCCTGTCACCCAGG	FRMD3	ENSG00000172159	2.3686481074679566	[489,303]	[92,1217]	9	dCas9-VP64	positive selection	2489029
83405717	83405740	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCATTGCACTCCAGCCTCGG	FRMD3	ENSG00000172159	-1.3426926137865989	[87,148]	[18,10]	-9	dCas9-VP64	positive selection	2489933
83464816	83464839	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGACCAGCCTGGCGAACATAG	FRMD3	ENSG00000172159	-0.9370734854043037	[131,209]	[38,18]	-8	dCas9-VP64	positive selection	2510148
83467897	83467920	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTGCATCTTAATATCCAGCAGG	FRMD3	ENSG00000172159	2.8779101144585235	[200,196]	[32,895]	9	dCas9-VP64	positive selection	2510528
83467827	83467850	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCACAGTAAATAGGTTGATGG	FRMD3	ENSG00000172159	0.23312939521570336	[81,237]	[51,67]	1	dCas9-VP64	positive selection	2510529
83467882	83467905	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTAATTGTTCAAGAACCTGCTGG	FRMD3	ENSG00000172159	-0.20340261052047473	[179,62]	[50,18]	-2	dCas9-VP64	positive selection	2510530
83332134	83332157	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGATCAGTTAGATTTTGCTGAGG	FRMD3	ENSG00000172159	-0.41538548246102935	[405,140]	[56,76]	-4	dCas9-VP64	positive selection	2510531
83332060	83332083	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCTGCTCTGTGCCCACCAGAGG	FRMD3	ENSG00000172159	1.1962446886301812	[284,227]	[241,145]	7	dCas9-VP64	positive selection	2510532
83332094	83332117	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGTGGCTTAGAGCAAGAAAGG	FRMD3	ENSG00000172159	1.7788186967568993	[109,89]	[207,22]	8	dCas9-VP64	positive selection	2510533
83267425	83267448	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATGATGAGGCATTTGGACAGGG	FRMD3	ENSG00000172159	0.3509629502965782	[113,83]	[57,24]	3	dCas9-VP64	positive selection	2510534
83267403	83267426	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTCCTCTGTTTTGGTCCGGAAGG	FRMD3	ENSG00000172159	-0.19369906728336786	[115,87]	[30,26]	-2	dCas9-VP64	positive selection	2510535
83267449	83267472	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGGGGACATTTGATTCTTAGG	FRMD3	ENSG00000172159	1.3075300589078611	[95,125]	[66,109]	7	dCas9-VP64	positive selection	2510536
83269677	83269700	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTCTCCCAGGCTAG	FRMD3	ENSG00000172159	-0.22012594312438807	[153,72]	[52,11]	-2	dCas9-VP64	positive selection	2513896
83273182	83273205	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAATAGAAAAGGGGGAAATGTGG	FRMD3	ENSG00000172159	0.026051413979125304	[91,92]	[41,19]	0	dCas9-VP64	positive selection	2514545
83369470	83369493	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAAGAG	FRMD3	ENSG00000172159	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517461
83309286	83309309	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACACACACACACACACACAGTGG	FRMD3	ENSG00000172159	-0.29192793722986554	[278,490]	[95,106]	-3	dCas9-VP64	positive selection	2519524
83476288	83476311	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACCTGG	FRMD3	ENSG00000172159	-0.3136691189391476	[37,20]	[8,5]	-3	dCas9-VP64	positive selection	2537745
83421976	83421999	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGGAGGCAGAGGCAAG	FRMD3	ENSG00000172159	4.207282944889167	[182,227]	[2502,59]	9	dCas9-VP64	positive selection	2565260
83538530	83538553	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCGTCGCGAGCCCGCCGGGGG	FRMD3	ENSG00000172159	-0.6939262439809952	[192,74]	[22,29]	-6	dCas9-VP64	positive selection	2566642
83538507	83538530	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCAGGCTCTGGGCGTCCTCGG	FRMD3	ENSG00000172159	0.8121298750768784	[420,348]	[88,343]	5	dCas9-VP64	positive selection	2566643
83267084	83267107	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.17777638872220586	[3,3]	[3,3]	4	hSpCas9	positive selection	2989305
83267155	83267178	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGCAGGCCGAGGAGACCAAGGG	FRMD3	ENSG00000172159	0.2830863701023157	[2,2]	[2,3]	6	hSpCas9	positive selection	2989306
83267154	83267177	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCAGGCCGAGGAGACCAAGGGG	FRMD3	ENSG00000172159	-0.0842127655159164	[3,3]	[2,3]	-1	hSpCas9	positive selection	2989307
83248412	83248435	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATCTTCCTCTTCACTAGGGGG	FRMD3	ENSG00000172159	0.150963605729865	[5,5]	[5,4]	3	hSpCas9	positive selection	2989308
83267084	83267107	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.045836676662902934	[3,3]	[3,1]	0	hSpCas9	positive selection	3057163
83267155	83267178	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGCAGGCCGAGGAGACCAAGGG	FRMD3	ENSG00000172159	-0.18681123296028873	[2,2]	[1,1]	-3	hSpCas9	positive selection	3057164
83267154	83267177	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCAGGCCGAGGAGACCAAGGGG	FRMD3	ENSG00000172159	0.02326225064817379	[3,3]	[4,1]	0	hSpCas9	positive selection	3057165
83248412	83248435	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATCTTCCTCTTCACTAGGGGG	FRMD3	ENSG00000172159	0.2557082493155123	[5,5]	[5,4]	4	hSpCas9	positive selection	3057166
83313712	83313735		+	24336571	A375	resistance to PLX after 7 days	AGCAAGTTAAATTCAGCAACTGG	FRMD3	ENSG00000172159	0.4492042334476317	[6,6]	[9,8]	9	hSpCas9	positive selection	3115332
83248182	83248205		-	24336571	A375	resistance to PLX after 7 days	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.3038403289920969	[24,23]	[18,20]	-8	hSpCas9	positive selection	3115333
83538141	83538164		-	24336571	A375	resistance to PLX after 7 days	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.13339976680414267	[17,21]	[23,19]	4	hSpCas9	positive selection	3115334
83389621	83389644		-	24336571	A375	resistance to PLX after 7 days	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.10844601798049547	[22,25]	[24,26]	3	hSpCas9	positive selection	3115335
83313652	83313675		+	24336571	A375	resistance to PLX after 7 days	GCAGTTACCTTGCATGGGTGAGG	FRMD3	ENSG00000172159	-0.3661738200712049	[20,22]	[14,18]	-9	hSpCas9	positive selection	3115336
83248441	83248464		+	24336571	A375	resistance to PLX after 7 days	TACTCCCGGGCTGCCTTCACTGG	FRMD3	ENSG00000172159	-0.1612274325371157	[30,29]	[24,28]	-5	hSpCas9	positive selection	3115339
83538102	83538125		+	24336571	A375	resistance to PLX after 7 days	TCTCCGAGTCGTCCAGCAGCCGG	FRMD3	ENSG00000172159	-0.39784727249931623	[16,18]	[12,14]	-9	hSpCas9	positive selection	3115340
83311932	83311955		-	24336571	A375	resistance to PLX after 7 days	TTTTTAGGATTCACAGCTGCAGG	FRMD3	ENSG00000172159	-0.03391294498730191	[21,22]	[20,21]	-1	hSpCas9	positive selection	3115341
83313712	83313735		+	24336571	A375	resistance to PLX after 14 days	AGCAAGTTAAATTCAGCAACTGG	FRMD3	ENSG00000172159	-0.2796622510709358	[7,9]	[2,2]	-3	hSpCas9	positive selection	3173125
83248182	83248205		-	24336571	A375	resistance to PLX after 14 days	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.6301308766466847	[26,27]	[6,7]	-7	hSpCas9	positive selection	3173126
83538141	83538164		-	24336571	A375	resistance to PLX after 14 days	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	-0.34773916975901187	[34,24]	[11,8]	-4	hSpCas9	positive selection	3173127
83389621	83389644		-	24336571	A375	resistance to PLX after 14 days	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	-0.24138002589457686	[27,20]	[8,9]	-3	hSpCas9	positive selection	3173128
83313652	83313675		+	24336571	A375	resistance to PLX after 14 days	GCAGTTACCTTGCATGGGTGAGG	FRMD3	ENSG00000172159	-0.8351922516580532	[23,21]	[5,4]	-8	hSpCas9	positive selection	3173129
83248441	83248464		+	24336571	A375	resistance to PLX after 14 days	TACTCCCGGGCTGCCTTCACTGG	FRMD3	ENSG00000172159	-0.408508637863627	[19,32]	[9,7]	-5	hSpCas9	positive selection	3173132
83538102	83538125		+	24336571	A375	resistance to PLX after 14 days	TCTCCGAGTCGTCCAGCAGCCGG	FRMD3	ENSG00000172159	-1.070963604290255	[20,19]	[4,2]	-9	hSpCas9	positive selection	3173133
83311932	83311955		-	24336571	A375	resistance to PLX after 14 days	TTTTTAGGATTCACAGCTGCAGG	FRMD3	ENSG00000172159	0.045636559895930184	[18,20]	[8,9]	0	hSpCas9	positive selection	3173134
83313712	83313735		+	24336571	A375	viability after 7 days	AGCAAGTTAAATTCAGCAACTGG	FRMD3	ENSG00000172159	0.07531721074609354	[6]	[6,6]	1	hSpCas9	negative selection	3230918
83248182	83248205		-	24336571	A375	viability after 7 days	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.31753030750245326	[32]	[24,23]	-4	hSpCas9	negative selection	3230919
83538141	83538164		-	24336571	A375	viability after 7 days	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.2909140739805461	[16]	[17,21]	4	hSpCas9	negative selection	3230920
83389621	83389644		-	24336571	A375	viability after 7 days	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.10526684883062021	[22]	[22,25]	1	hSpCas9	negative selection	3230921
83313652	83313675		+	24336571	A375	viability after 7 days	GCAGTTACCTTGCATGGGTGAGG	FRMD3	ENSG00000172159	0.4258534973504138	[16]	[20,22]	6	hSpCas9	negative selection	3230922
83248441	83248464		+	24336571	A375	viability after 7 days	TACTCCCGGGCTGCCTTCACTGG	FRMD3	ENSG00000172159	0.965009662450224	[15]	[30,29]	9	hSpCas9	negative selection	3230925
83538102	83538125		+	24336571	A375	viability after 7 days	TCTCCGAGTCGTCCAGCAGCCGG	FRMD3	ENSG00000172159	0.01383717838148496	[18]	[16,18]	0	hSpCas9	negative selection	3230926
83311932	83311955		-	24336571	A375	viability after 7 days	TTTTTAGGATTCACAGCTGCAGG	FRMD3	ENSG00000172159	0.13371616161518374	[21]	[21,22]	2	hSpCas9	negative selection	3230927
83313712	83313735		+	24336571	A375	viability after 14 days	AGCAAGTTAAATTCAGCAACTGG	FRMD3	ENSG00000172159	0.4658234048036177	[6]	[7,9]	6	hSpCas9	negative selection	3288711
83248182	83248205		-	24336571	A375	viability after 14 days	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.15320688141454508	[32]	[26,27]	-2	hSpCas9	negative selection	3288712
83538141	83538164		-	24336571	A375	viability after 14 days	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.863625981942372	[16]	[34,24]	9	hSpCas9	negative selection	3288713
83389621	83389644		-	24336571	A375	viability after 14 days	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.1444664578646705	[22]	[27,20]	1	hSpCas9	negative selection	3288714
83313652	83313675		+	24336571	A375	viability after 14 days	GCAGTTACCTTGCATGGGTGAGG	FRMD3	ENSG00000172159	0.533164263832413	[16]	[23,21]	6	hSpCas9	negative selection	3288715
83248441	83248464		+	24336571	A375	viability after 14 days	TACTCCCGGGCTGCCTTCACTGG	FRMD3	ENSG00000172159	0.784729408727719	[15]	[19,32]	8	hSpCas9	negative selection	3288718
83538102	83538125		+	24336571	A375	viability after 14 days	TCTCCGAGTCGTCCAGCAGCCGG	FRMD3	ENSG00000172159	0.19764419390169202	[18]	[20,19]	2	hSpCas9	negative selection	3288719
83311932	83311955		-	24336571	A375	viability after 14 days	TTTTTAGGATTCACAGCTGCAGG	FRMD3	ENSG00000172159	-0.02458045413215937	[21]	[18,20]	0	hSpCas9	negative selection	3288720
83538142	83538165	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	2.7385277979364893	[132,95]	[0,8]	8	hSpCas9	positive selection	3350538
83538114	83538137	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	-0.9101739266589994	[289,284]	[0,0]	-6	hSpCas9	positive selection	3350539
83389621	83389644	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	-0.29414959504886656	[201,172]	[0,0]	-2	hSpCas9	positive selection	3350540
83389651	83389674	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.04645453673126785	[157,157]	[0,0]	0	hSpCas9	positive selection	3369746
83538141	83538164	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	-1.3720304086337745	[395,395]	[0,0]	-8	hSpCas9	positive selection	3369747
83538076	83538099	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	1.8997742068277512	[40,40]	[0,0]	7	hSpCas9	positive selection	3369748
83267084	83267107	9	-	26780180	HT29	viability (Avana library 4 designs)	ACGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.884914389757391	[]	[]	3	hSpCas9	negative selection	3426253
83267155	83267178	9	-	26780180	HT29	viability (Avana library 4 designs)	ATGCAGGCCGAGGAGACCAAGGG	FRMD3	ENSG00000172159	1.30959289764728	[]	[]	5	hSpCas9	negative selection	3426254
83267154	83267177	9	-	26780180	HT29	viability (Avana library 4 designs)	TGCAGGCCGAGGAGACCAAGGGG	FRMD3	ENSG00000172159	0.587880337322267	[]	[]	2	hSpCas9	negative selection	3426255
83248411	83248434	9	+	26780180	HT29	viability (Avana library 4 designs)	TTATCTTCCTCTTCACTAGGGGG	FRMD3	ENSG00000172159	-0.303298728561414	[]	[]	-5	hSpCas9	negative selection	3426256
83248411	83248434	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATCTTCCTCTTCACTAGGGGG	FRMD3	ENSG00000172159	-3.87079402125323	[]	[]	-4	hSpCas9	negative selection	3508829
83267155	83267178	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCAGGCCGAGGAGACCAAGGG	FRMD3	ENSG00000172159	3.78618460210803	[]	[]	6	hSpCas9	negative selection	3508830
83267084	83267107	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	2.91877001087888	[]	[]	4	hSpCas9	negative selection	3508831
83267154	83267177	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCAGGCCGAGGAGACCAAGGGG	FRMD3	ENSG00000172159	3.99593542330852	[]	[]	6	hSpCas9	negative selection	3508832
83248459	83248482	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGGGGAGCTGGAGATCAAGGG	FRMD3	ENSG00000172159	3.85805097032366	[]	[]	6	hSpCas9	negative selection	3508833
83267165	83267188	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCTGGGCCATGCAGGCCGAGG	FRMD3	ENSG00000172159	4.84847243400656	[]	[]	8	hSpCas9	negative selection	3508834
83248411	83248434	9	+	26780180	A375	viability (Avana lentiGuide)	TTATCTTCCTCTTCACTAGGGGG	FRMD3	ENSG00000172159	-1.94503346681373	[]	[]	-3	hSpCas9	negative selection	3617488
83267155	83267178	9	-	26780180	A375	viability (Avana lentiGuide)	ATGCAGGCCGAGGAGACCAAGGG	FRMD3	ENSG00000172159	1.42457743551806	[]	[]	1	hSpCas9	negative selection	3617489
83267084	83267107	9	-	26780180	A375	viability (Avana lentiGuide)	ACGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	-3.74493060306011	[]	[]	-6	hSpCas9	negative selection	3617490
83267154	83267177	9	-	26780180	A375	viability (Avana lentiGuide)	TGCAGGCCGAGGAGACCAAGGGG	FRMD3	ENSG00000172159	3.35419401091378	[]	[]	3	hSpCas9	negative selection	3617491
83248459	83248482	9	+	26780180	A375	viability (Avana lentiGuide)	ACTGGGGAGCTGGAGATCAAGGG	FRMD3	ENSG00000172159	6.90689222667058	[]	[]	5	hSpCas9	negative selection	3617492
83267165	83267188	9	-	26780180	A375	viability (Avana lentiGuide)	GCCCTGGGCCATGCAGGCCGAGG	FRMD3	ENSG00000172159	7.10236357016542	[]	[]	5	hSpCas9	negative selection	3617493
83248411	83248434	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATCTTCCTCTTCACTAGGGGG	FRMD3	ENSG00000172159	-0.3348200670202125	[7]	[6,5]	-5	hSpCas9	positive selection	3726147
83267155	83267178	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCAGGCCGAGGAGACCAAGGG	FRMD3	ENSG00000172159	0.0655863178965872	[4]	[5,4]	1	hSpCas9	positive selection	3726148
83267084	83267107	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.07708296343296306	[5]	[6,4]	2	hSpCas9	positive selection	3726149
83267154	83267177	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCAGGCCGAGGAGACCAAGGGG	FRMD3	ENSG00000172159	0.21202792356616457	[4]	[5,5]	6	hSpCas9	positive selection	3726150
83248459	83248482	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGGGGAGCTGGAGATCAAGGG	FRMD3	ENSG00000172159	0.19691728050974067	[4]	[5,5]	5	hSpCas9	positive selection	3726151
83267165	83267188	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCTGGGCCATGCAGGCCGAGG	FRMD3	ENSG00000172159	0.3748897345362787	[4]	[5,4]	9	hSpCas9	positive selection	3726152
83248411	83248434	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATCTTCCTCTTCACTAGGGGG	FRMD3	ENSG00000172159	0.2736189624233149	[7]	[7,7]	7	hSpCas9	positive selection	3834754
83267155	83267178	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCAGGCCGAGGAGACCAAGGG	FRMD3	ENSG00000172159	-1.2681063129009136	[4]	[0,0]	-9	hSpCas9	positive selection	3834755
83267084	83267107	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.1927589824075212	[5]	[5,5]	5	hSpCas9	positive selection	3834756
83267154	83267177	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCAGGCCGAGGAGACCAAGGGG	FRMD3	ENSG00000172159	0.23042474553191247	[5]	[4,6]	6	hSpCas9	positive selection	3834757
83248459	83248482	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGGGGAGCTGGAGATCAAGGG	FRMD3	ENSG00000172159	-0.25464266699831095	[5]	[2,3]	-3	hSpCas9	positive selection	3834758
83267165	83267188	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCTGGGCCATGCAGGCCGAGG	FRMD3	ENSG00000172159	-0.5713769871345407	[4]	[3,1]	-6	hSpCas9	positive selection	3834759
83538076	83538099	9	+	26780180	A375	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	1.24607042003788	[]	[]	6	hSpCas9	negative selection	3941918
83538141	83538164	9	-	26780180	A375	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.816799049218731	[]	[]	3	hSpCas9	negative selection	3941919
83389621	83389644	9	-	26780180	A375	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.533795095900057	[]	[]	1	hSpCas9	negative selection	3941920
83389651	83389674	9	-	26780180	A375	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	1.30289891003524	[]	[]	7	hSpCas9	negative selection	3941921
83538142	83538165	9	+	26780180	A375	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	1.40703704825845	[]	[]	7	hSpCas9	negative selection	3941922
83538114	83538137	9	-	26780180	A375	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	1.39151136973277	[]	[]	7	hSpCas9	negative selection	3941923
83538076	83538099	9	+	26780180	HT29	viability (GeCKOv2 library)	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	1.63977040350092	[]	[]	8	hSpCas9	negative selection	4049884
83538141	83538164	9	-	26780180	HT29	viability (GeCKOv2 library)	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	1.44746095869262	[]	[]	7	hSpCas9	negative selection	4049885
83389621	83389644	9	-	26780180	HT29	viability (GeCKOv2 library)	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	-0.687803430866635	[]	[]	-9	hSpCas9	negative selection	4049886
83389651	83389674	9	-	26780180	HT29	viability (GeCKOv2 library)	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	1.28415752551759	[]	[]	6	hSpCas9	negative selection	4049887
83538142	83538165	9	+	26780180	HT29	viability (GeCKOv2 library)	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	1.41017762069093	[]	[]	7	hSpCas9	negative selection	4049888
83538114	83538137	9	-	26780180	HT29	viability (GeCKOv2 library)	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	1.11536971398055	[]	[]	5	hSpCas9	negative selection	4049889
83313712	83313735	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAAGTTAAATTCAGCAACTGG	FRMD3	ENSG00000172159	-0.09732932617984813	[3]	[2,1]	-2	hSpCas9	positive selection	4138423
83248182	83248205	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.05187915321803893	[4]	[2,2]	-1	hSpCas9	positive selection	4138424
83538141	83538164	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.1501127506683099	[4]	[2,3]	4	hSpCas9	positive selection	4138425
83389621	83389644	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.4820378135697937	[4]	[5,3]	9	hSpCas9	positive selection	4138426
83313652	83313675	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGTTACCTTGCATGGGTGAGG	FRMD3	ENSG00000172159	-0.03142119644455246	[4]	[2,2]	0	hSpCas9	positive selection	4138427
83248441	83248464	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACTCCCGGGCTGCCTTCACTGG	FRMD3	ENSG00000172159	0.1995297615024181	[4]	[3,3]	5	hSpCas9	positive selection	4138430
83538102	83538125	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCCGAGTCGTCCAGCAGCCGG	FRMD3	ENSG00000172159	-0.060326253826889886	[3]	[2,1]	-1	hSpCas9	positive selection	4138431
83311932	83311955	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTTTAGGATTCACAGCTGCAGG	FRMD3	ENSG00000172159	-0.02868459877730889	[4]	[2,3]	0	hSpCas9	positive selection	4138432
83313712	83313735	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAAGTTAAATTCAGCAACTGG	FRMD3	ENSG00000172159	1.8070314338360354	[1]	[0,0,3,4]	9	hSpCas9	positive selection	4202445
83248182	83248205	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.09599560162357601	[4]	[4,1,1,0]	-1	hSpCas9	positive selection	4202446
83538141	83538164	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	1.157215361667674	[4]	[2,4,5,3]	8	hSpCas9	positive selection	4202447
83389621	83389644	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	1.418714513924829	[4]	[5,4,4,5]	9	hSpCas9	positive selection	4202448
83313652	83313675	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGTTACCTTGCATGGGTGAGG	FRMD3	ENSG00000172159	0.8673753238850388	[3]	[0,0,1,3]	6	hSpCas9	positive selection	4202449
83248441	83248464	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACTCCCGGGCTGCCTTCACTGG	FRMD3	ENSG00000172159	0.0007335273558808364	[2]	[1,0,2,0]	0	hSpCas9	positive selection	4202452
83538102	83538125	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCCGAGTCGTCCAGCAGCCGG	FRMD3	ENSG00000172159	-0.1032977915158435	[4]	[0,1,4,0]	-1	hSpCas9	positive selection	4202453
83311932	83311955	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTTTAGGATTCACAGCTGCAGG	FRMD3	ENSG00000172159	0.24238728276880467	[3]	[3,2,1,0]	2	hSpCas9	positive selection	4202454
83538142	83538165	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.3017309101970976	[3]	[3,0]	-6	hSpCas9	positive selection	4271699
83538114	83538137	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	-0.2002400668850418	[3]	[3,1]	-4	hSpCas9	positive selection	4271700
83389621	83389644	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5043346619462689	[3]	[4,3]	9	hSpCas9	positive selection	4271701
83389651	83389674	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.3523678942951419	[2]	[2,0]	-6	hSpCas9	positive selection	4335961
83538141	83538164	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.1435512178339413	[3]	[3,2]	3	hSpCas9	positive selection	4335962
83538076	83538099	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.7605343593740311	[1]	[0,0]	-9	hSpCas9	positive selection	4335963
83248253	83248275	9	-	27760321	OCIAML3	viability	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	1.0503270158433398	[368,255]	[363,677]	9	hSpCas9	negative selection	4402043
83248283	83248305	9	+	27760321	OCIAML3	viability	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.5595394801432589	[277,215]	[204,383]	6	hSpCas9	negative selection	4402044
83248428	83248450	9	+	27760321	OCIAML3	viability	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.8634366517443931	[380,259]	[390,527]	8	hSpCas9	negative selection	4402045
83248496	83248518	9	-	27760321	OCIAML3	viability	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.6984001224797493	[264,229]	[288,344]	8	hSpCas9	negative selection	4402046
83290617	83290639	9	+	27760321	OCIAML3	viability	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	0.056029337934465406	[978,1084]	[692,1043]	0	hSpCas9	negative selection	4402047
83290679	83290701	9	+	27760321	OCIAML3	viability	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.12917833293705067	[468,404]	[334,421]	1	hSpCas9	negative selection	4402048
83349678	83349700	9	-	27760321	OCIAML3	viability	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	-1.4029579518347233	[99,98]	[22,37]	-8	hSpCas9	negative selection	4402049
83538121	83538143	9	-	27760321	OCIAML3	viability	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	1.0059631313092574	[544,429]	[574,1002]	9	hSpCas9	negative selection	4402050
83538141	83538163	9	-	27760321	OCIAML3	viability	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.45012924078451927	[559,461]	[404,723]	5	hSpCas9	negative selection	4402051
83299108	83299130	9	-	27760321	OCIAML3	viability	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	0.7633713280658969	[26,28]	[16,63]	8	hSpCas9	negative selection	4402052
83299154	83299176	9	+	27760321	OCIAML3	viability	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	-0.09044817689086782	[199,218]	[134,180]	-1	hSpCas9	negative selection	4402053
83309529	83309551	9	+	27760321	OCIAML3	viability	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	0.46611934150807	[110,87]	[108,103]	5	hSpCas9	negative selection	4402054
83313677	83313699	9	-	27760321	OCIAML3	viability	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	-0.14335695681165106	[517,392]	[355,272]	-1	hSpCas9	negative selection	4402055
83343183	83343205	9	+	27760321	OCIAML3	viability	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	-1.089675272178618	[57,48]	[6,35]	-7	hSpCas9	negative selection	4402056
83267084	83267106	9	-	27760321	OCIAML3	viability	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.6998486410267772	[360,305]	[350,514]	8	hSpCas9	negative selection	4402057
83248253	83248275	9	-	27760321	OCIAML2	viability	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.0328303320795616	[368,255]	[246,266]	0	hSpCas9	negative selection	4485506
83248283	83248305	9	+	27760321	OCIAML2	viability	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.48285947076133257	[277,215]	[256,303]	6	hSpCas9	negative selection	4485507
83248428	83248450	9	+	27760321	OCIAML2	viability	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.3592859808328279	[380,259]	[271,402]	5	hSpCas9	negative selection	4485508
83248496	83248518	9	-	27760321	OCIAML2	viability	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.39055898280996104	[264,229]	[206,333]	5	hSpCas9	negative selection	4485509
83290617	83290639	9	+	27760321	OCIAML2	viability	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	0.6695045271986146	[978,1084]	[1115,1629]	8	hSpCas9	negative selection	4485510
83290679	83290701	9	+	27760321	OCIAML2	viability	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.23667071177983187	[468,404]	[335,519]	3	hSpCas9	negative selection	4485511
83349678	83349700	9	-	27760321	OCIAML2	viability	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.1201646010032964	[99,98]	[63,118]	1	hSpCas9	negative selection	4485512
83538121	83538143	9	-	27760321	OCIAML2	viability	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.18121562547709932	[544,429]	[297,636]	2	hSpCas9	negative selection	4485513
83538141	83538163	9	-	27760321	OCIAML2	viability	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.7911091898728764	[559,461]	[623,827]	9	hSpCas9	negative selection	4485514
83299108	83299130	9	-	27760321	OCIAML2	viability	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	0.05670360319327372	[26,28]	[24,21]	0	hSpCas9	negative selection	4485515
83299154	83299176	9	+	27760321	OCIAML2	viability	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	0.7392263242958605	[199,218]	[217,372]	8	hSpCas9	negative selection	4485516
83309529	83309551	9	+	27760321	OCIAML2	viability	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	-0.48042061660179636	[110,87]	[49,66]	-5	hSpCas9	negative selection	4485517
83313677	83313699	9	-	27760321	OCIAML2	viability	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	-0.29569080635450723	[517,392]	[305,286]	-4	hSpCas9	negative selection	4485518
83343183	83343205	9	+	27760321	OCIAML2	viability	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	-0.3994721275549695	[57,48]	[14,55]	-5	hSpCas9	negative selection	4485519
83267084	83267106	9	-	27760321	OCIAML2	viability	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.46799169241424743	[360,305]	[307,455]	6	hSpCas9	negative selection	4485520
83248253	83248275	9	-	27760321	MV411	viability	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	-0.5828681385339157	[368,255]	[0,338]	-4	hSpCas9	negative selection	4568969
83248283	83248305	9	+	27760321	MV411	viability	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.15418923572682353	[277,215]	[68,346]	1	hSpCas9	negative selection	4568970
83248428	83248450	9	+	27760321	MV411	viability	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.20520933811653952	[380,259]	[299,151]	1	hSpCas9	negative selection	4568971
83248496	83248518	9	-	27760321	MV411	viability	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	-0.8916914307518141	[264,229]	[96,73]	-5	hSpCas9	negative selection	4568972
83290617	83290639	9	+	27760321	MV411	viability	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	0.027874361193511277	[978,1084]	[350,1222]	0	hSpCas9	negative selection	4568973
83290679	83290701	9	+	27760321	MV411	viability	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	-1.342514405750087	[468,404]	[120,101]	-7	hSpCas9	negative selection	4568974
83349678	83349700	9	-	27760321	MV411	viability	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.7004735857400295	[99,98]	[114,94]	5	hSpCas9	negative selection	4568975
83538121	83538143	9	-	27760321	MV411	viability	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	-0.9384217615287374	[544,429]	[155,182]	-6	hSpCas9	negative selection	4568976
83538141	83538163	9	-	27760321	MV411	viability	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.8371374341939177	[559,461]	[432,849]	6	hSpCas9	negative selection	4568977
83299108	83299130	9	-	27760321	MV411	viability	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	0.448991025465046	[26,28]	[0,61]	3	hSpCas9	negative selection	4568978
83299154	83299176	9	+	27760321	MV411	viability	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	-0.8366882027307248	[199,218]	[19,164]	-5	hSpCas9	negative selection	4568979
83309529	83309551	9	+	27760321	MV411	viability	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	0.0625520856334445	[110,87]	[0,168]	0	hSpCas9	negative selection	4568980
83313677	83313699	9	-	27760321	MV411	viability	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	1.9679335974149201	[517,392]	[1560,573]	9	hSpCas9	negative selection	4568981
83343183	83343205	9	+	27760321	MV411	viability	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	0.4309054164464987	[57,48]	[72,8]	3	hSpCas9	negative selection	4568982
83267084	83267106	9	-	27760321	MV411	viability	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.8004566248289471	[360,305]	[94,812]	6	hSpCas9	negative selection	4568983
83248253	83248275	9	-	27760321	HL60	viability	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	-0.35938135050304465	[368,255]	[235,154]	-4	hSpCas9	negative selection	4652432
83248283	83248305	9	+	27760321	HL60	viability	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.5316993055876854	[277,215]	[260,319]	6	hSpCas9	negative selection	4652433
83248428	83248450	9	+	27760321	HL60	viability	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	-0.42676305997644126	[380,259]	[254,125]	-5	hSpCas9	negative selection	4652434
83248496	83248518	9	-	27760321	HL60	viability	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.042948597863731175	[264,229]	[116,303]	0	hSpCas9	negative selection	4652435
83290617	83290639	9	+	27760321	HL60	viability	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	0.6355613438011452	[978,1084]	[1086,1565]	7	hSpCas9	negative selection	4652436
83290679	83290701	9	+	27760321	HL60	viability	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.4391001297422232	[468,404]	[437,529]	5	hSpCas9	negative selection	4652437
83349678	83349700	9	-	27760321	HL60	viability	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	-0.3957306281328923	[99,98]	[43,80]	-4	hSpCas9	negative selection	4652438
83538121	83538143	9	-	27760321	HL60	viability	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.22579161422109187	[544,429]	[502,419]	2	hSpCas9	negative selection	4652439
83538141	83538163	9	-	27760321	HL60	viability	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.9395466996878183	[559,461]	[760,834]	8	hSpCas9	negative selection	4652440
83299108	83299130	9	-	27760321	HL60	viability	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	0.5951062309436432	[26,28]	[26,42]	7	hSpCas9	negative selection	4652441
83299154	83299176	9	+	27760321	HL60	viability	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	-0.29716001920502144	[199,218]	[98,183]	-3	hSpCas9	negative selection	4652442
83309529	83309551	9	+	27760321	HL60	viability	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	-0.08212470831319374	[110,87]	[102,47]	-1	hSpCas9	negative selection	4652443
83313677	83313699	9	-	27760321	HL60	viability	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.14480979838953262	[517,392]	[377,439]	1	hSpCas9	negative selection	4652444
83343183	83343205	9	+	27760321	HL60	viability	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	-0.2674755256230483	[57,48]	[41,29]	-3	hSpCas9	negative selection	4652445
83267084	83267106	9	-	27760321	HL60	viability	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.24996301456621609	[360,305]	[333,310]	3	hSpCas9	negative selection	4652446
83248253	83248275	9	-	27760321	HT1080	viability	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	2.2148161379104265	[255,199]	[614,209]	9	hSpCas9	negative selection	4735895
83248283	83248305	9	+	27760321	HT1080	viability	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.42557600244352384	[215,168]	[155,44]	2	hSpCas9	negative selection	4735896
83248428	83248450	9	+	27760321	HT1080	viability	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	-0.2362165167582908	[259,202]	[73,82]	-1	hSpCas9	negative selection	4735897
83248496	83248518	9	-	27760321	HT1080	viability	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	1.1028317581856122	[229,179]	[57,303]	6	hSpCas9	negative selection	4735898
83290617	83290639	9	+	27760321	HT1080	viability	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	-0.9888959621165958	[1084,846]	[233,149]	-4	hSpCas9	negative selection	4735899
83290679	83290701	9	+	27760321	HT1080	viability	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	-0.13835800965959064	[404,315]	[129,130]	0	hSpCas9	negative selection	4735900
83349678	83349700	9	-	27760321	HT1080	viability	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.5209698339834996	[98,76]	[66,31]	2	hSpCas9	negative selection	4735901
83538121	83538143	9	-	27760321	HT1080	viability	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	-7.253490080167756	[429,335]	[0,0]	-9	hSpCas9	negative selection	4735902
83538141	83538163	9	-	27760321	HT1080	viability	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.7863595795572369	[461,360]	[266,299]	4	hSpCas9	negative selection	4735903
83299108	83299130	9	-	27760321	HT1080	viability	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	4.112058788863868	[28,22]	[100,264]	9	hSpCas9	negative selection	4735904
83299154	83299176	9	+	27760321	HT1080	viability	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	2.1433456295194984	[218,170]	[515,153]	9	hSpCas9	negative selection	4735905
83309529	83309551	9	+	27760321	HT1080	viability	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	-4.967217813396074	[87,68]	[0,0]	-8	hSpCas9	negative selection	4735906
83313677	83313699	9	-	27760321	HT1080	viability	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.21280225888669974	[392,306]	[110,216]	1	hSpCas9	negative selection	4735907
83343183	83343205	9	+	27760321	HT1080	viability	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	0.780048519415883	[48,37]	[55,0]	4	hSpCas9	negative selection	4735908
83267084	83267106	9	-	27760321	HT1080	viability	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	3.0767759776777215	[305,238]	[1030,789]	9	hSpCas9	negative selection	4735909
83248253	83248275	9	-	27760321	HT29	viability after 7 days	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.3670378380701344	[255,199]	[632,283,256]	5	hSpCas9	negative selection	4819358
83248283	83248305	9	+	27760321	HT29	viability after 7 days	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.20867629055633707	[215,168]	[275,378,203]	3	hSpCas9	negative selection	4819359
83248428	83248450	9	+	27760321	HT29	viability after 7 days	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.22932294713554374	[259,202]	[415,263,374]	3	hSpCas9	negative selection	4819360
83248496	83248518	9	-	27760321	HT29	viability after 7 days	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.1094103565017378	[229,179]	[455,288,136]	1	hSpCas9	negative selection	4819361
83290617	83290639	9	+	27760321	HT29	viability after 7 days	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	-0.5034300571566989	[1084,846]	[944,783,906]	-6	hSpCas9	negative selection	4819362
83290679	83290701	9	+	27760321	HT29	viability after 7 days	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.2387474565704907	[404,315]	[554,504,579]	3	hSpCas9	negative selection	4819363
83349678	83349700	9	-	27760321	HT29	viability after 7 days	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	-0.07468052170770756	[98,76]	[137,66,120]	-1	hSpCas9	negative selection	4819364
83538121	83538143	9	-	27760321	HT29	viability after 7 days	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.3628459880649916	[429,335]	[998,442,512]	5	hSpCas9	negative selection	4819365
83538141	83538163	9	-	27760321	HT29	viability after 7 days	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.33626579664316686	[461,360]	[701,705,601]	5	hSpCas9	negative selection	4819366
83299108	83299130	9	-	27760321	HT29	viability after 7 days	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	-0.834630792644393	[28,22]	[49,0,9]	-8	hSpCas9	negative selection	4819367
83299154	83299176	9	+	27760321	HT29	viability after 7 days	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	-0.4782867344843541	[218,170]	[269,181,102]	-6	hSpCas9	negative selection	4819368
83309529	83309551	9	+	27760321	HT29	viability after 7 days	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	-1.3816706870152018	[87,68]	[58,50,9]	-9	hSpCas9	negative selection	4819369
83313677	83313699	9	-	27760321	HT29	viability after 7 days	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.4245904467387706	[392,306]	[570,679,556]	6	hSpCas9	negative selection	4819370
83343183	83343205	9	+	27760321	HT29	viability after 7 days	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	0.2885864223453396	[48,37]	[71,23,107]	4	hSpCas9	negative selection	4819371
83267084	83267106	9	-	27760321	HT29	viability after 7 days	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.8612198776409821	[305,238]	[449,638,787]	9	hSpCas9	negative selection	4819372
83248253	83248275	9	-	27760321	HT29	viability after 25 days	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.2687097451874342	[255,199]	[391,207,338]	2	hSpCas9	negative selection	4902821
83248283	83248305	9	+	27760321	HT29	viability after 25 days	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.8792729429485951	[215,168]	[353,524,329]	8	hSpCas9	negative selection	4902822
83248428	83248450	9	+	27760321	HT29	viability after 25 days	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.5448451063424115	[259,202]	[320,302,554]	6	hSpCas9	negative selection	4902823
83248496	83248518	9	-	27760321	HT29	viability after 25 days	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.041275328710522086	[229,179]	[159,189,393]	0	hSpCas9	negative selection	4902824
83290617	83290639	9	+	27760321	HT29	viability after 25 days	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	0.2604247638060264	[1084,846]	[1163,1532,1272]	2	hSpCas9	negative selection	4902825
83290679	83290701	9	+	27760321	HT29	viability after 25 days	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.009703641962751124	[404,315]	[194,427,659]	0	hSpCas9	negative selection	4902826
83349678	83349700	9	-	27760321	HT29	viability after 25 days	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.6480119076003557	[98,76]	[301,66,86]	7	hSpCas9	negative selection	4902827
83538121	83538143	9	-	27760321	HT29	viability after 25 days	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.813122674607218	[429,335]	[670,762,890]	8	hSpCas9	negative selection	4902828
83538141	83538163	9	-	27760321	HT29	viability after 25 days	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.5570214961550153	[461,360]	[625,647,817]	6	hSpCas9	negative selection	4902829
83299108	83299130	9	-	27760321	HT29	viability after 25 days	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	-1.138965007730421	[28,22]	[0,11,29]	-7	hSpCas9	negative selection	4902830
83299154	83299176	9	+	27760321	HT29	viability after 25 days	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	0.08607515390863418	[218,170]	[166,341,200]	0	hSpCas9	negative selection	4902831
83309529	83309551	9	+	27760321	HT29	viability after 25 days	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	0.2718203610693579	[87,68]	[97,114,112]	3	hSpCas9	negative selection	4902832
83313677	83313699	9	-	27760321	HT29	viability after 25 days	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.04834552031580406	[392,306]	[197,511,558]	0	hSpCas9	negative selection	4902833
83343183	83343205	9	+	27760321	HT29	viability after 25 days	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	-0.8162342064891264	[48,37]	[45,4,32]	-6	hSpCas9	negative selection	4902834
83267084	83267106	9	-	27760321	HT29	viability after 25 days	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.9028802292684974	[305,238]	[563,576,608]	9	hSpCas9	negative selection	4902835
83248253	83248275	9	-	27760321	HT29	viability after 22 days	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.10569658392309456	[255,199]	[274,304,270]	1	hSpCas9	negative selection	4986284
83248283	83248305	9	+	27760321	HT29	viability after 22 days	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.4470119155479964	[215,168]	[295,251,362]	5	hSpCas9	negative selection	4986285
83248428	83248450	9	+	27760321	HT29	viability after 22 days	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.5623140382064563	[259,202]	[331,488,365]	6	hSpCas9	negative selection	4986286
83248496	83248518	9	-	27760321	HT29	viability after 22 days	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.3271721621225855	[229,179]	[299,191,400]	3	hSpCas9	negative selection	4986287
83290617	83290639	9	+	27760321	HT29	viability after 22 days	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	-0.08846765932810086	[1084,846]	[712,1509,935]	-1	hSpCas9	negative selection	4986288
83290679	83290701	9	+	27760321	HT29	viability after 22 days	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	-0.09468820387653287	[404,315]	[236,228,711]	-1	hSpCas9	negative selection	4986289
83349678	83349700	9	-	27760321	HT29	viability after 22 days	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.4376059456961301	[98,76]	[187,74,148]	5	hSpCas9	negative selection	4986290
83538121	83538143	9	-	27760321	HT29	viability after 22 days	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.4898752759976652	[429,335]	[574,642,648]	5	hSpCas9	negative selection	4986291
83538141	83538163	9	-	27760321	HT29	viability after 22 days	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.738381452200376	[461,360]	[1105,640,623]	8	hSpCas9	negative selection	4986292
83299108	83299130	9	-	27760321	HT29	viability after 22 days	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	-1.4143392408165112	[28,22]	[2,28,1]	-7	hSpCas9	negative selection	4986293
83299154	83299176	9	+	27760321	HT29	viability after 22 days	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	0.16595762061675745	[218,170]	[335,219,199]	1	hSpCas9	negative selection	4986294
83309529	83309551	9	+	27760321	HT29	viability after 22 days	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	0.011710007570037373	[87,68]	[162,81,26]	0	hSpCas9	negative selection	4986295
83313677	83313699	9	-	27760321	HT29	viability after 22 days	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.03968492032947296	[392,306]	[298,422,529]	0	hSpCas9	negative selection	4986296
83343183	83343205	9	+	27760321	HT29	viability after 22 days	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	0.10209077926653887	[48,37]	[58,19,82]	1	hSpCas9	negative selection	4986297
83267084	83267106	9	-	27760321	HT29	viability after 22 days	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.811303640133038	[305,238]	[298,637,729]	8	hSpCas9	negative selection	4986298
83248253	83248275	9	-	27760321	HT29	viability after 19 days	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.7958735378452871	[255,199]	[299,644,398]	7	hSpCas9	negative selection	5069747
83248283	83248305	9	+	27760321	HT29	viability after 19 days	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.5137081530213452	[215,168]	[389,304,257]	5	hSpCas9	negative selection	5069748
83248428	83248450	9	+	27760321	HT29	viability after 19 days	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.4499162716432057	[259,202]	[569,454,91]	4	hSpCas9	negative selection	5069749
83248496	83248518	9	-	27760321	HT29	viability after 19 days	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.17180926612802938	[229,179]	[401,228,178]	1	hSpCas9	negative selection	5069750
83290617	83290639	9	+	27760321	HT29	viability after 19 days	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	0.08871313305175033	[1084,846]	[1143,1560,828]	0	hSpCas9	negative selection	5069751
83290679	83290701	9	+	27760321	HT29	viability after 19 days	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.24437102900365643	[404,315]	[339,478,624]	2	hSpCas9	negative selection	5069752
83349678	83349700	9	-	27760321	HT29	viability after 19 days	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	-1.4251613664436258	[98,76]	[73,25,16]	-7	hSpCas9	negative selection	5069753
83538121	83538143	9	-	27760321	HT29	viability after 19 days	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.9230796393256654	[429,335]	[620,658,1175]	8	hSpCas9	negative selection	5069754
83538141	83538163	9	-	27760321	HT29	viability after 19 days	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.7100166461723143	[461,360]	[926,637,760]	7	hSpCas9	negative selection	5069755
83299108	83299130	9	-	27760321	HT29	viability after 19 days	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	0.3263472225893267	[28,22]	[14,67,26]	3	hSpCas9	negative selection	5069756
83299154	83299176	9	+	27760321	HT29	viability after 19 days	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	0.364107969018015	[218,170]	[380,395,100]	3	hSpCas9	negative selection	5069757
83309529	83309551	9	+	27760321	HT29	viability after 19 days	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	-1.3007782352233246	[87,68]	[45,18,44]	-7	hSpCas9	negative selection	5069758
83313677	83313699	9	-	27760321	HT29	viability after 19 days	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.1573487954044325	[392,306]	[606,199,544]	1	hSpCas9	negative selection	5069759
83343183	83343205	9	+	27760321	HT29	viability after 19 days	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	0.912429228306078	[48,37]	[88,170,22]	8	hSpCas9	negative selection	5069760
83267084	83267106	9	-	27760321	HT29	viability after 19 days	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.9351618270600117	[305,238]	[640,524,624]	8	hSpCas9	negative selection	5069761
83248253	83248275	9	-	27760321	HT29	viability after 16 days	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.7330272697181854	[255,199]	[435,427,408]	8	hSpCas9	negative selection	5153210
83248283	83248305	9	+	27760321	HT29	viability after 16 days	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.31743506416971956	[215,168]	[216,434,143]	3	hSpCas9	negative selection	5153211
83248428	83248450	9	+	27760321	HT29	viability after 16 days	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.5714882377728677	[259,202]	[488,364,310]	6	hSpCas9	negative selection	5153212
83248496	83248518	9	-	27760321	HT29	viability after 16 days	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.48262616142665443	[229,179]	[248,311,393]	5	hSpCas9	negative selection	5153213
83290617	83290639	9	+	27760321	HT29	viability after 16 days	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	-0.25126010122499154	[1084,846]	[976,1078,669]	-3	hSpCas9	negative selection	5153214
83290679	83290701	9	+	27760321	HT29	viability after 16 days	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.3793167573888727	[404,315]	[334,594,623]	4	hSpCas9	negative selection	5153215
83349678	83349700	9	-	27760321	HT29	viability after 16 days	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.8490203427213519	[98,76]	[163,124,242]	8	hSpCas9	negative selection	5153216
83538121	83538143	9	-	27760321	HT29	viability after 16 days	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.604854211926831	[429,335]	[831,578,562]	7	hSpCas9	negative selection	5153217
83538141	83538163	9	-	27760321	HT29	viability after 16 days	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.6117839684936315	[461,360]	[559,783,750]	7	hSpCas9	negative selection	5153218
83299108	83299130	9	-	27760321	HT29	viability after 16 days	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	-0.5400113627610792	[28,22]	[45,1,14]	-5	hSpCas9	negative selection	5153219
83299154	83299176	9	+	27760321	HT29	viability after 16 days	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	0.16266763339526347	[218,170]	[296,304,133]	1	hSpCas9	negative selection	5153220
83309529	83309551	9	+	27760321	HT29	viability after 16 days	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	0.24200394526821567	[87,68]	[109,189,9]	2	hSpCas9	negative selection	5153221
83313677	83313699	9	-	27760321	HT29	viability after 16 days	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	-0.04912607467628207	[392,306]	[527,360,260]	0	hSpCas9	negative selection	5153222
83343183	83343205	9	+	27760321	HT29	viability after 16 days	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	-0.21798760044059806	[48,37]	[54,30,40]	-2	hSpCas9	negative selection	5153223
83267084	83267106	9	-	27760321	HT29	viability after 16 days	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.9732178488859782	[305,238]	[677,716,404]	9	hSpCas9	negative selection	5153224
83248253	83248275	9	-	27760321	HT29	viability after 13 days	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	-0.03867837432064147	[255,199]	[182,183,396]	0	hSpCas9	negative selection	5236673
83248283	83248305	9	+	27760321	HT29	viability after 13 days	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.6906744682163111	[215,168]	[400,330,349]	8	hSpCas9	negative selection	5236674
83248428	83248450	9	+	27760321	HT29	viability after 13 days	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.3531849976761124	[259,202]	[402,265,358]	4	hSpCas9	negative selection	5236675
83248496	83248518	9	-	27760321	HT29	viability after 13 days	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.562912114549494	[229,179]	[389,380,286]	7	hSpCas9	negative selection	5236676
83290617	83290639	9	+	27760321	HT29	viability after 13 days	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	-0.11631334960547535	[1084,846]	[946,1075,1075]	-1	hSpCas9	negative selection	5236677
83290679	83290701	9	+	27760321	HT29	viability after 13 days	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.04019945977470873	[404,315]	[403,471,414]	0	hSpCas9	negative selection	5236678
83349678	83349700	9	-	27760321	HT29	viability after 13 days	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	-1.2090831271055351	[98,76]	[20,75,35]	-8	hSpCas9	negative selection	5236679
83538121	83538143	9	-	27760321	HT29	viability after 13 days	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.5177206044557874	[429,335]	[621,761,530]	6	hSpCas9	negative selection	5236680
83538141	83538163	9	-	27760321	HT29	viability after 13 days	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.6598236315141011	[461,360]	[697,796,766]	8	hSpCas9	negative selection	5236681
83299108	83299130	9	-	27760321	HT29	viability after 13 days	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	-0.7036414302637417	[28,22]	[0,41,12]	-6	hSpCas9	negative selection	5236682
83299154	83299176	9	+	27760321	HT29	viability after 13 days	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	-0.18010763369241933	[218,170]	[180,319,103]	-2	hSpCas9	negative selection	5236683
83309529	83309551	9	+	27760321	HT29	viability after 13 days	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	-0.3388355257957678	[87,68]	[70,122,24]	-4	hSpCas9	negative selection	5236684
83313677	83313699	9	-	27760321	HT29	viability after 13 days	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.045210080085847815	[392,306]	[438,520,303]	0	hSpCas9	negative selection	5236685
83343183	83343205	9	+	27760321	HT29	viability after 13 days	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	0.05596708714079224	[48,37]	[89,10,55]	0	hSpCas9	negative selection	5236686
83267084	83267106	9	-	27760321	HT29	viability after 13 days	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.5050623704488816	[305,238]	[392,656,304]	6	hSpCas9	negative selection	5236687
83248253	83248275	9	-	27760321	HT29	viability after 10 days	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.18946528336038576	[255,199]	[449,210,309]	2	hSpCas9	negative selection	5320136
83248283	83248305	9	+	27760321	HT29	viability after 10 days	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.3198972702203733	[215,168]	[267,331,300]	4	hSpCas9	negative selection	5320137
83248428	83248450	9	+	27760321	HT29	viability after 10 days	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.47980720964117485	[259,202]	[253,685,279]	6	hSpCas9	negative selection	5320138
83248496	83248518	9	-	27760321	HT29	viability after 10 days	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	0.10790769546509826	[229,179]	[317,164,339]	1	hSpCas9	negative selection	5320139
83290617	83290639	9	+	27760321	HT29	viability after 10 days	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	-0.34896758399651295	[1084,846]	[951,948,939]	-4	hSpCas9	negative selection	5320140
83290679	83290701	9	+	27760321	HT29	viability after 10 days	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	-0.390628206378168	[404,315]	[220,278,523]	-5	hSpCas9	negative selection	5320141
83349678	83349700	9	-	27760321	HT29	viability after 10 days	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.07809341988538065	[98,76]	[110,120,115]	1	hSpCas9	negative selection	5320142
83538121	83538143	9	-	27760321	HT29	viability after 10 days	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.4896205608462748	[429,335]	[452,762,797]	6	hSpCas9	negative selection	5320143
83538141	83538163	9	-	27760321	HT29	viability after 10 days	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.2081846186611399	[461,360]	[684,619,478]	2	hSpCas9	negative selection	5320144
83299108	83299130	9	-	27760321	HT29	viability after 10 days	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	0.2994705881490116	[28,22]	[5,115,0]	4	hSpCas9	negative selection	5320145
83299154	83299176	9	+	27760321	HT29	viability after 10 days	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	-0.8897754976224027	[218,170]	[123,150,119]	-7	hSpCas9	negative selection	5320146
83309529	83309551	9	+	27760321	HT29	viability after 10 days	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	-1.0417566482802827	[87,68]	[32,36,71]	-8	hSpCas9	negative selection	5320147
83313677	83313699	9	-	27760321	HT29	viability after 10 days	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.40335002324739083	[392,306]	[574,661,500]	5	hSpCas9	negative selection	5320148
83343183	83343205	9	+	27760321	HT29	viability after 10 days	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	-0.19435157279234438	[48,37]	[86,22,31]	-3	hSpCas9	negative selection	5320149
83267084	83267106	9	-	27760321	HT29	viability after 10 days	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.9905972686701345	[305,238]	[498,692,832]	9	hSpCas9	negative selection	5320150
83248253	83248275	9	-	27760321	MOLM13	viability	ACAGATTCATTTGAGGATCTGG	FRMD3	ENSG00000172159	0.03376230883926645	[368,255]	[246,119]	0	hSpCas9	negative selection	5403599
83248283	83248305	9	+	27760321	MOLM13	viability	TTTCCAACTCAAGCCTAGAAGG	FRMD3	ENSG00000172159	0.738036186857913	[277,215]	[293,176]	5	hSpCas9	negative selection	5403600
83248428	83248450	9	+	27760321	MOLM13	viability	AGGGGGATCTTCATACTCCCGG	FRMD3	ENSG00000172159	0.7628081972812838	[380,259]	[523,114]	5	hSpCas9	negative selection	5403601
83248496	83248518	9	-	27760321	MOLM13	viability	GGTGTTCCATTGCCTAAAGAGG	FRMD3	ENSG00000172159	-0.10119117519293985	[264,229]	[225,47]	0	hSpCas9	negative selection	5403602
83290617	83290639	9	+	27760321	MOLM13	viability	AGTTCTTCTTCTTGCTCGCTGG	FRMD3	ENSG00000172159	1.4082409897680739	[978,1084]	[2108,1086]	8	hSpCas9	negative selection	5403603
83290679	83290701	9	+	27760321	MOLM13	viability	GAGCTGTTTGTTCAAGGAGTGG	FRMD3	ENSG00000172159	0.9485839942961103	[468,404]	[325,600]	6	hSpCas9	negative selection	5403604
83349678	83349700	9	-	27760321	MOLM13	viability	GATTAAAGAAGAGCTCACAAGG	FRMD3	ENSG00000172159	0.9917079820608974	[99,98]	[4,202]	7	hSpCas9	negative selection	5403605
83538121	83538143	9	-	27760321	MOLM13	viability	GGAGATGAGATGCACCATCCGG	FRMD3	ENSG00000172159	0.7551515527822318	[544,429]	[551,383]	5	hSpCas9	negative selection	5403606
83538141	83538163	9	-	27760321	MOLM13	viability	AGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	1.5769134176383486	[559,461]	[611,1063]	9	hSpCas9	negative selection	5403607
83299108	83299130	9	-	27760321	MOLM13	viability	AAGTAGATTTCGATATAGGTGG	FRMD3	ENSG00000172159	-3.9905591281533868	[26,28]	[0,0]	-9	hSpCas9	negative selection	5403608
83299154	83299176	9	+	27760321	MOLM13	viability	GATACAGTCTTGATCTGACTGG	FRMD3	ENSG00000172159	-0.2090370949374314	[199,218]	[62,136]	-1	hSpCas9	negative selection	5403609
83309529	83309551	9	+	27760321	MOLM13	viability	CACTTACTTATAAAAGGCCTGG	FRMD3	ENSG00000172159	1.8591938261424643	[110,87]	[48,332]	9	hSpCas9	negative selection	5403610
83313677	83313699	9	-	27760321	MOLM13	viability	ACTTTGGAAACCTACGGGGTGG	FRMD3	ENSG00000172159	0.17236587509809848	[517,392]	[511,95]	1	hSpCas9	negative selection	5403611
83343183	83343205	9	+	27760321	MOLM13	viability	GACTTACCTTGAACAATACAGG	FRMD3	ENSG00000172159	-4.910498863916471	[57,48]	[0,0]	-9	hSpCas9	negative selection	5403612
83267084	83267106	9	-	27760321	MOLM13	viability	CGAAGCCTCCAATTGCACATGG	FRMD3	ENSG00000172159	0.38879608356040757	[360,305]	[184,296]	2	hSpCas9	negative selection	5403613
83537906	83537929	9	-	27661255	K562	viability	GGCCTTATCCTGGCATGGAGGGG	FRMD3	ENSG00000172159	-0.08984633922894603	[540,499]	[394,387]	-3	dCas9-KRAB	negative selection	5480843
83537989	83538012	9	-	27661255	K562	viability	GAGAACAAGGAACCCACTCCCGG	FRMD3	ENSG00000172159	0.19874170004625258	[988,1245]	[1070,976]	7	dCas9-KRAB	negative selection	5480844
83538002	83538025	9	-	27661255	K562	viability	GCGGTGGGCATGCGAGAACAAGG	FRMD3	ENSG00000172159	0.11142757443111928	[1170,1358]	[1119,1061]	4	dCas9-KRAB	negative selection	5480845
83538142	83538165	9	+	27260156	BXPC3	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.01978104626268906	[665]	[675,685,765,694]	0	hSpCas9	negative selection	5544159
83538114	83538137	9	-	27260156	BXPC3	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.17085741677503152	[850]	[1080,1081,871,940]	4	hSpCas9	negative selection	5544160
83389621	83389644	9	-	27260156	BXPC3	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.4723696947360668	[468]	[643,522,849,720]	8	hSpCas9	negative selection	5544161
83389651	83389674	9	-	27260156	BXPC3	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.03340304275922948	[407]	[331,487,289,576]	0	hSpCas9	negative selection	5608421
83538141	83538164	9	-	27260156	BXPC3	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.20151878557048852	[854]	[966,1049,987,1114]	4	hSpCas9	negative selection	5608422
83538076	83538099	9	+	27260156	BXPC3	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.12802634897499732	[176]	[181,182,224,223]	3	hSpCas9	negative selection	5608423
83538142	83538165	9	+	27260156	A673	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.04780197445841239	[665]	[842,797,614,849]	-1	hSpCas9	negative selection	5665410
83538114	83538137	9	-	27260156	A673	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.13210947494166525	[850]	[1380,1081,968,1074]	3	hSpCas9	negative selection	5665411
83389621	83389644	9	-	27260156	A673	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.2653308625111033	[468]	[821,620,515,771]	6	hSpCas9	negative selection	5665412
83389651	83389674	9	-	27260156	A673	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.06452467027067652	[407]	[440,451,505,470]	-2	hSpCas9	negative selection	5729672
83538141	83538164	9	-	27260156	A673	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.1592337804278683	[854]	[1078,974,1041,1504]	4	hSpCas9	negative selection	5729673
83538076	83538099	9	+	27260156	A673	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.1779666973078724	[176]	[199,195,276,286]	4	hSpCas9	negative selection	5729674
83538142	83538165	9	+	27260156	A375	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.010358954045917801	[665]	[986,511,907,697]	0	hSpCas9	negative selection	5786661
83538114	83538137	9	-	27260156	A375	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.15454593430203445	[850]	[957,1322,1301,892]	2	hSpCas9	negative selection	5786662
83389621	83389644	9	-	27260156	A375	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.72830457172266	[468]	[758,951,988,928]	9	hSpCas9	negative selection	5786663
83389651	83389674	9	-	27260156	A375	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.17699334721115734	[407]	[663,661,537,331]	2	hSpCas9	negative selection	5850923
83538141	83538164	9	-	27260156	A375	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.23840033329867416	[854]	[1220,1225,1175,1100]	3	hSpCas9	negative selection	5850924
83538076	83538099	9	+	27260156	A375	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.3839744899473527	[176]	[220,363,237,267]	5	hSpCas9	negative selection	5850925
83538142	83538165	9	+	27260156	COLO741	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.16963204790578595	[665]	[826,915,546]	-4	hSpCas9	negative selection	5907912
83538114	83538137	9	-	27260156	COLO741	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.20969736014644347	[850]	[1404,1248,1136]	4	hSpCas9	negative selection	5907913
83389621	83389644	9	-	27260156	COLO741	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.49244072800741484	[468]	[985,848,713]	8	hSpCas9	negative selection	5907914
83389651	83389674	9	-	27260156	COLO741	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.10923304195416231	[407]	[525,626,531]	2	hSpCas9	negative selection	5972174
83538141	83538164	9	-	27260156	COLO741	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.007063921432706066	[854]	[1453,985,895]	0	hSpCas9	negative selection	5972175
83538076	83538099	9	+	27260156	COLO741	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.3605838829394783	[176]	[264,307,294]	7	hSpCas9	negative selection	5972176
83538142	83538165	9	+	27260156	CAL120	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.027584884942126964	[665]	[852,771,908]	0	hSpCas9	negative selection	6029163
83538114	83538137	9	-	27260156	CAL120	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	-0.22259193860012072	[850]	[926,876,920]	-3	hSpCas9	negative selection	6029164
83389621	83389644	9	-	27260156	CAL120	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.9673377372417851	[468]	[1717,1005,791]	9	hSpCas9	negative selection	6029165
83389651	83389674	9	-	27260156	CAL120	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.05492548272216305	[407]	[349,485,606]	-1	hSpCas9	negative selection	6093425
83538141	83538164	9	-	27260156	CAL120	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.5084589185980697	[854]	[1502,1616,1419]	7	hSpCas9	negative selection	6093426
83538076	83538099	9	+	27260156	CAL120	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.11833934691495762	[176]	[299,336,91]	1	hSpCas9	negative selection	6093427
83538142	83538165	9	+	27260156	CADOES1	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.2024515489466867	[665]	[534,533,552,530]	-4	hSpCas9	negative selection	6150414
83538114	83538137	9	-	27260156	CADOES1	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.23360983443186611	[850]	[1020,863,830,1008]	4	hSpCas9	negative selection	6150415
83389621	83389644	9	-	27260156	CADOES1	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5746535557703174	[468]	[690,723,447,738]	8	hSpCas9	negative selection	6150416
83389651	83389674	9	-	27260156	CADOES1	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.10912593410128338	[407]	[330,427,283,364]	-2	hSpCas9	negative selection	6214676
83538141	83538164	9	-	27260156	CADOES1	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.2846785065576223	[854]	[1155,964,738,1015]	5	hSpCas9	negative selection	6214677
83538076	83538099	9	+	27260156	CADOES1	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.014032080418433512	[176]	[154,182,180,131]	0	hSpCas9	negative selection	6214678
83538142	83538165	9	+	27260156	EWS502	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.18745355426534538	[665]	[452,728,612,701]	-3	hSpCas9	negative selection	6271665
83538114	83538137	9	-	27260156	EWS502	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.3303325404058738	[850]	[1089,1061,1213,1174]	6	hSpCas9	negative selection	6271666
83389621	83389644	9	-	27260156	EWS502	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.8616812387076587	[468]	[823,809,862,1139]	9	hSpCas9	negative selection	6271667
83389651	83389674	9	-	27260156	EWS502	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.15933572600492288	[407]	[399,355,390,399]	-3	hSpCas9	negative selection	6335927
83538141	83538164	9	-	27260156	EWS502	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.362243128913347	[854]	[1265,1043,1031,1310]	6	hSpCas9	negative selection	6335928
83538076	83538099	9	+	27260156	EWS502	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.32979815040301075	[176]	[157,228,242,327]	6	hSpCas9	negative selection	6335929
83538142	83538165	9	+	27260156	EW8	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.16214191684758494	[665]	[710,617,538,568]	3	hSpCas9	negative selection	6392916
83538114	83538137	9	-	27260156	EW8	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.1558077610755283	[850]	[963,703,573,882]	3	hSpCas9	negative selection	6392917
83389621	83389644	9	-	27260156	EW8	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5253890488294007	[468]	[550,510,593,522]	8	hSpCas9	negative selection	6392918
83389651	83389674	9	-	27260156	EW8	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.03302751726749664	[407]	[312,331,338,303]	0	hSpCas9	negative selection	6457178
83538141	83538164	9	-	27260156	EW8	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.40139055779075616	[854]	[917,909,772,1080]	7	hSpCas9	negative selection	6457179
83538076	83538099	9	+	27260156	EW8	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.23441848750894945	[176]	[195,140,176,161]	4	hSpCas9	negative selection	6457180
83538142	83538165	9	+	27260156	CORL105	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.1514552437211571	[665]	[646,668,582,887]	-3	hSpCas9	negative selection	6514167
83538114	83538137	9	-	27260156	CORL105	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.24851010765283366	[850]	[1184,1170,1458,962]	4	hSpCas9	negative selection	6514168
83389621	83389644	9	-	27260156	CORL105	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.862069125670802	[468]	[1048,813,826,1278]	9	hSpCas9	negative selection	6514169
83389651	83389674	9	-	27260156	CORL105	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.23012433002140573	[407]	[345,324,446,515]	-4	hSpCas9	negative selection	6578429
83538141	83538164	9	-	27260156	CORL105	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.2832824028016059	[854]	[1382,1108,1311,1090]	5	hSpCas9	negative selection	6578430
83538076	83538099	9	+	27260156	CORL105	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.3870774857882835	[176]	[315,184,277,308]	7	hSpCas9	negative selection	6578431
83538142	83538165	9	+	27260156	HS294T	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.018207166845485956	[665]	[203,240,214,413]	0	hSpCas9	negative selection	6635418
83538114	83538137	9	-	27260156	HS294T	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.7225807907980061	[850]	[555,491,596,521]	8	hSpCas9	negative selection	6635419
83389621	83389644	9	-	27260156	HS294T	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	1.123172235955393	[468]	[448,261,431,442]	9	hSpCas9	negative selection	6635420
83389651	83389674	9	-	27260156	HS294T	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.08038758574890534	[407]	[178,130,164,112]	-1	hSpCas9	negative selection	6699680
83538141	83538164	9	-	27260156	HS294T	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.5037855173409682	[854]	[356,425,537,583]	6	hSpCas9	negative selection	6699681
83538076	83538099	9	+	27260156	HS294T	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.4188196126669602	[176]	[53,68,90,168]	5	hSpCas9	negative selection	6699682
83538142	83538165	9	+	27260156	HCC44	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.2894724664948257	[665]	[1047,762,899,991]	5	hSpCas9	negative selection	6756669
83538114	83538137	9	-	27260156	HCC44	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.3543819485927294	[850]	[1201,1181,1216,1309]	6	hSpCas9	negative selection	6756670
83389621	83389644	9	-	27260156	HCC44	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.664590035347413	[468]	[763,730,1222,716]	9	hSpCas9	negative selection	6756671
83389651	83389674	9	-	27260156	HCC44	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.058804881590232755	[407]	[666,434,379,443]	0	hSpCas9	negative selection	6820931
83538141	83538164	9	-	27260156	HCC44	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.1941505876261913	[854]	[1227,940,1173,1118]	3	hSpCas9	negative selection	6820932
83538076	83538099	9	+	27260156	HCC44	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.3762512740060142	[176]	[321,137,386,235]	6	hSpCas9	negative selection	6820933
83538142	83538165	9	+	27260156	G402	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.41944799784152453	[665]	[1079,778,1286,1173]	5	hSpCas9	negative selection	6877920
83538114	83538137	9	-	27260156	G402	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.4797156134908226	[850]	[1933,1318,1082,1509]	6	hSpCas9	negative selection	6877921
83389621	83389644	9	-	27260156	G402	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.6330198753815168	[468]	[547,1289,776,904]	7	hSpCas9	negative selection	6877922
83389651	83389674	9	-	27260156	G402	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.26505304990656575	[407]	[580,599,149,361]	-3	hSpCas9	negative selection	6942182
83538141	83538164	9	-	27260156	G402	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.6961100524961259	[854]	[1718,1837,1580,1631]	8	hSpCas9	negative selection	6942183
83538076	83538099	9	+	27260156	G402	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.6876743196869709	[176]	[221,324,165,642]	8	hSpCas9	negative selection	6942184
83538142	83538165	9	+	27260156	L33	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.01754609023421405	[665]	[602,286,367,742]	0	hSpCas9	negative selection	6999171
83538114	83538137	9	-	27260156	L33	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.14072404023440688	[850]	[889,398,600,933]	3	hSpCas9	negative selection	6999172
83389621	83389644	9	-	27260156	L33	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.4897169406420395	[468]	[618,273,405,700]	8	hSpCas9	negative selection	6999173
83389651	83389674	9	-	27260156	L33	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.3637967737362018	[407]	[275,131,207,339]	-7	hSpCas9	negative selection	7063433
83538141	83538164	9	-	27260156	L33	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	-0.10590686903722446	[854]	[784,309,551,758]	-2	hSpCas9	negative selection	7063434
83538076	83538099	9	+	27260156	L33	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.1589498162419274	[176]	[144,116,39,139]	-4	hSpCas9	negative selection	7063435
83538142	83538165	9	+	27260156	K562	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.34701462720374754	[665]	[1248,947,560,344]	4	hSpCas9	negative selection	7120422
83538114	83538137	9	-	27260156	K562	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.5559820549751929	[850]	[1096,1142,1152,1050]	7	hSpCas9	negative selection	7120423
83389621	83389644	9	-	27260156	K562	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.6282560109235702	[468]	[915,464,827,402]	7	hSpCas9	negative selection	7120424
83389651	83389674	9	-	27260156	K562	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.21288816902575888	[407]	[240,388,718,322]	2	hSpCas9	negative selection	7184684
83538141	83538164	9	-	27260156	K562	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.38217812834682197	[854]	[832,1138,1254,747]	5	hSpCas9	negative selection	7184685
83538076	83538099	9	+	27260156	K562	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.13778155107241186	[176]	[157,187,159,75]	-2	hSpCas9	negative selection	7184686
83538142	83538165	9	+	27260156	HT29	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.0474083683474823	[665]	[774,884,951,739]	0	hSpCas9	negative selection	7241673
83538114	83538137	9	-	27260156	HT29	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	-0.046028492095934403	[850]	[999,971,1122,913]	-1	hSpCas9	negative selection	7241674
83389621	83389644	9	-	27260156	HT29	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5467655185099854	[468]	[890,915,769,767]	9	hSpCas9	negative selection	7241675
83389651	83389674	9	-	27260156	HT29	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.025363643591934493	[407]	[530,657,513,285]	0	hSpCas9	negative selection	7305935
83538141	83538164	9	-	27260156	HT29	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.18215913355652158	[854]	[1344,1228,1130,1037]	3	hSpCas9	negative selection	7305936
83538076	83538099	9	+	27260156	HT29	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.05626041706100393	[176]	[201,237,194,253]	1	hSpCas9	negative selection	7305937
83538142	83538165	9	+	27260156	MHHES1	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.23646741220849166	[665]	[1217,948,868,593]	4	hSpCas9	negative selection	7362924
83538114	83538137	9	-	27260156	MHHES1	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.26153643881851696	[850]	[1337,1588,882,886]	5	hSpCas9	negative selection	7362925
83389621	83389644	9	-	27260156	MHHES1	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.7290535755904716	[468]	[1059,941,807,733]	9	hSpCas9	negative selection	7362926
83389651	83389674	9	-	27260156	MHHES1	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.01741218578147835	[407]	[463,572,485,361]	0	hSpCas9	negative selection	7427186
83538141	83538164	9	-	27260156	MHHES1	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.32993582223177054	[854]	[1733,1239,847,1084]	6	hSpCas9	negative selection	7427187
83538076	83538099	9	+	27260156	MHHES1	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.23505972292271005	[176]	[253,155,213,79]	-4	hSpCas9	negative selection	7427188
83538142	83538165	9	+	27260156	MEWO	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.18305810635222453	[665]	[821,745,575]	4	hSpCas9	negative selection	7484175
83538114	83538137	9	-	27260156	MEWO	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.2728446226986311	[850]	[1126,861,928]	6	hSpCas9	negative selection	7484176
83389621	83389644	9	-	27260156	MEWO	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.41030507790811716	[468]	[722,446,606]	8	hSpCas9	negative selection	7484177
83389651	83389674	9	-	27260156	MEWO	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.05019403909908088	[407]	[495,416,291]	1	hSpCas9	negative selection	7548437
83538141	83538164	9	-	27260156	MEWO	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.14373317930078477	[854]	[1041,797,841]	3	hSpCas9	negative selection	7548438
83538076	83538099	9	+	27260156	MEWO	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.1649767441867478	[176]	[221,178,162]	3	hSpCas9	negative selection	7548439
83538142	83538165	9	+	27260156	LNCAPCLONEFGC	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.12321322996262196	[665]	[671,570,654,734]	2	hSpCas9	negative selection	7605426
83538114	83538137	9	-	27260156	LNCAPCLONEFGC	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.1975479966046686	[850]	[846,942,787,939]	3	hSpCas9	negative selection	7605427
83389621	83389644	9	-	27260156	LNCAPCLONEFGC	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.7691068421043777	[468]	[610,871,770,640]	9	hSpCas9	negative selection	7605428
83389651	83389674	9	-	27260156	LNCAPCLONEFGC	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.058945418670464045	[407]	[446,315,417,366]	0	hSpCas9	negative selection	7669688
83538141	83538164	9	-	27260156	LNCAPCLONEFGC	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.31016530428092315	[854]	[769,848,1084,1165]	5	hSpCas9	negative selection	7669689
83538076	83538099	9	+	27260156	LNCAPCLONEFGC	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.22929077945898757	[176]	[213,185,232,124]	3	hSpCas9	negative selection	7669690
83538142	83538165	9	+	27260156	PANC0327	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.24277940778847273	[665]	[961,609,641,618]	3	hSpCas9	negative selection	7726677
83538114	83538137	9	-	27260156	PANC0327	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.42090392517116826	[850]	[1314,830,961,987]	6	hSpCas9	negative selection	7726678
83389621	83389644	9	-	27260156	PANC0327	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5956566378872483	[468]	[637,653,769,453]	8	hSpCas9	negative selection	7726679
83389651	83389674	9	-	27260156	PANC0327	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.18622704908173374	[407]	[380,179,316,418]	-3	hSpCas9	negative selection	7790939
83538141	83538164	9	-	27260156	PANC0327	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.1551512897212659	[854]	[1158,710,904,650]	2	hSpCas9	negative selection	7790940
83538076	83538099	9	+	27260156	PANC0327	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.06529074642741794	[176]	[111,58,318,119]	-1	hSpCas9	negative selection	7790941
83538142	83538165	9	+	27260156	NCIH2009	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.05427940105276208	[665]	[1013,1040,849]	0	hSpCas9	negative selection	7847928
83538114	83538137	9	-	27260156	NCIH2009	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.4623792677932582	[850]	[2246,1424,1363]	6	hSpCas9	negative selection	7847929
83389621	83389644	9	-	27260156	NCIH2009	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.685566049764066	[468]	[1277,952,974]	8	hSpCas9	negative selection	7847930
83389651	83389674	9	-	27260156	NCIH2009	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.0856288155219691	[407]	[692,388,752]	1	hSpCas9	negative selection	7912190
83538141	83538164	9	-	27260156	NCIH2009	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.3798241209755302	[854]	[1774,1445,1484]	5	hSpCas9	negative selection	7912191
83538076	83538099	9	+	27260156	NCIH2009	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.28658785420848454	[176]	[285,208,407]	4	hSpCas9	negative selection	7912192
83538142	83538165	9	+	27260156	NCIH1373	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.034027341791983634	[665]	[776,868,603,209]	0	hSpCas9	negative selection	7969179
83538114	83538137	9	-	27260156	NCIH1373	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	-0.1474172815128394	[850]	[971,957,576,249]	-1	hSpCas9	negative selection	7969180
83389621	83389644	9	-	27260156	NCIH1373	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.9658725338020929	[468]	[850,1214,831,306]	8	hSpCas9	negative selection	7969181
83389651	83389674	9	-	27260156	NCIH1373	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.12744361754460867	[407]	[813,308,339,160]	1	hSpCas9	negative selection	8033441
83538141	83538164	9	-	27260156	NCIH1373	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.21538642369843597	[854]	[1056,870,887,442]	2	hSpCas9	negative selection	8033442
83538076	83538099	9	+	27260156	NCIH1373	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.8772507545231678	[176]	[182,99,58,26]	-7	hSpCas9	negative selection	8033443
83538142	83538165	9	+	27260156	PATU8902	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.29879049531249013	[665]	[978,1109,653,2048]	3	hSpCas9	negative selection	8090430
83538114	83538137	9	-	27260156	PATU8902	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.47482594537258416	[850]	[1707,1812,1424,1691]	5	hSpCas9	negative selection	8090431
83389621	83389644	9	-	27260156	PATU8902	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.7451906965180062	[468]	[1168,1653,758,846]	7	hSpCas9	negative selection	8090432
83389651	83389674	9	-	27260156	PATU8902	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.2854960511904854	[407]	[703,525,386,1298]	3	hSpCas9	negative selection	8154692
83538141	83538164	9	-	27260156	PATU8902	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.8857449566542439	[854]	[1771,2076,2321,2637]	8	hSpCas9	negative selection	8154693
83538076	83538099	9	+	27260156	PATU8902	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.8442109689063992	[176]	[726,212,429,388]	8	hSpCas9	negative selection	8154694
83538142	83538165	9	+	27260156	PANC1	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.1436666292773493	[665]	[514,566,496,496]	-2	hSpCas9	negative selection	8211681
83538114	83538137	9	-	27260156	PANC1	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.153793775034487	[850]	[952,786,680,808]	2	hSpCas9	negative selection	8211682
83389621	83389644	9	-	27260156	PANC1	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.3918337228254284	[468]	[474,657,645,379]	6	hSpCas9	negative selection	8211683
83389651	83389674	9	-	27260156	PANC1	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.24379860985926796	[407]	[362,334,279,219]	-4	hSpCas9	negative selection	8275943
83538141	83538164	9	-	27260156	PANC1	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	-0.0019346469825203272	[854]	[849,1050,632,489]	0	hSpCas9	negative selection	8275944
83538076	83538099	9	+	27260156	PANC1	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.4092574847825424	[176]	[226,314,82,200]	6	hSpCas9	negative selection	8275945
83538142	83538165	9	+	27260156	PANC0813	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.15977152742686251	[665]	[1108,870,798,743]	2	hSpCas9	negative selection	8332932
83538114	83538137	9	-	27260156	PANC0813	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.4015693094132494	[850]	[1474,1572,1012,1235]	6	hSpCas9	negative selection	8332933
83389621	83389644	9	-	27260156	PANC0813	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.7713775067066606	[468]	[1305,838,817,835]	9	hSpCas9	negative selection	8332934
83389651	83389674	9	-	27260156	PANC0813	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.13470966657577532	[407]	[685,374,605,455]	2	hSpCas9	negative selection	8397194
83538141	83538164	9	-	27260156	PANC0813	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.3052548551900025	[854]	[1075,1074,1243,1534]	5	hSpCas9	negative selection	8397195
83538076	83538099	9	+	27260156	PANC0813	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.4838886763213106	[176]	[434,234,221,283]	7	hSpCas9	negative selection	8397196
83538142	83538165	9	+	27260156	RDES	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.08925085339416106	[665]	[642,616,1158,898]	1	hSpCas9	negative selection	8454183
83538114	83538137	9	-	27260156	RDES	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.16085835878400656	[850]	[880,1084,1090,1375]	2	hSpCas9	negative selection	8454184
83389621	83389644	9	-	27260156	RDES	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5165281517016654	[468]	[552,911,799,843]	8	hSpCas9	negative selection	8454185
83389651	83389674	9	-	27260156	RDES	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.08487739676686984	[407]	[412,484,482,633]	1	hSpCas9	negative selection	8518445
83538141	83538164	9	-	27260156	RDES	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.4243276719184783	[854]	[958,1439,1397,1545]	6	hSpCas9	negative selection	8518446
83538076	83538099	9	+	27260156	RDES	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.34053118073510635	[176]	[272,114,356,297]	5	hSpCas9	negative selection	8518447
83538142	83538165	9	+	27260156	PC3	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.061679854298512526	[665]	[488,586,1125,761]	1	hSpCas9	negative selection	8575434
83538114	83538137	9	-	27260156	PC3	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.0953602677073434	[850]	[578,846,1364,1076]	2	hSpCas9	negative selection	8575435
83389621	83389644	9	-	27260156	PC3	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.2490521686774526	[468]	[393,581,809,542]	5	hSpCas9	negative selection	8575436
83389651	83389674	9	-	27260156	PC3	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.0053750119439779365	[407]	[210,355,1019,337]	0	hSpCas9	negative selection	8639696
83538141	83538164	9	-	27260156	PC3	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.3507762431600139	[854]	[782,1249,1712,835]	7	hSpCas9	negative selection	8639697
83538076	83538099	9	+	27260156	PC3	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.11558930495581432	[176]	[101,153,230,203]	-3	hSpCas9	negative selection	8639698
83538142	83538165	9	+	27260156	PATU8988T	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.3598914807539094	[665]	[726,1097,473,1052]	6	hSpCas9	negative selection	8696685
83538114	83538137	9	-	27260156	PATU8988T	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.5284109642481446	[850]	[1017,1406,1057,1291]	8	hSpCas9	negative selection	8696686
83389621	83389644	9	-	27260156	PATU8988T	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.36847255648291805	[468]	[479,852,420,615]	6	hSpCas9	negative selection	8696687
83389651	83389674	9	-	27260156	PATU8988T	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.01101908251653319	[407]	[353,667,247,341]	0	hSpCas9	negative selection	8760947
83538141	83538164	9	-	27260156	PATU8988T	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.21708030637242448	[854]	[850,1111,1066,811]	4	hSpCas9	negative selection	8760948
83538076	83538099	9	+	27260156	PATU8988T	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.2894454302452667	[176]	[114,184,227,313]	5	hSpCas9	negative selection	8760949
83538142	83538165	9	+	27260156	T47D	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.02201679302742099	[665]	[780,743,798,831]	0	hSpCas9	negative selection	8817936
83538114	83538137	9	-	27260156	T47D	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.15429548218121825	[850]	[1091,1080,1060,1183]	3	hSpCas9	negative selection	8817937
83389621	83389644	9	-	27260156	T47D	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.4718835501474928	[468]	[713,714,805,799]	8	hSpCas9	negative selection	8817938
83389651	83389674	9	-	27260156	T47D	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.10876861079934783	[407]	[460,436,499,361]	-2	hSpCas9	negative selection	8882198
83538141	83538164	9	-	27260156	T47D	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.15541205870060226	[854]	[1119,1022,1095,1208]	3	hSpCas9	negative selection	8882199
83538076	83538099	9	+	27260156	T47D	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.18424529583822036	[176]	[254,197,273,211]	4	hSpCas9	negative selection	8882200
83538142	83538165	9	+	27260156	SU8686	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.06621081222920489	[665]	[547,729,677,838]	1	hSpCas9	negative selection	8939187
83538114	83538137	9	-	27260156	SU8686	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.249069373760623	[850]	[805,919,1044,1317]	4	hSpCas9	negative selection	8939188
83389621	83389644	9	-	27260156	SU8686	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.7243668788816336	[468]	[671,624,904,923]	9	hSpCas9	negative selection	8939189
83389651	83389674	9	-	27260156	SU8686	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.07725543133985871	[407]	[278,265,537,497]	-1	hSpCas9	negative selection	9003449
83538141	83538164	9	-	27260156	SU8686	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.16245736488592843	[854]	[1038,791,881,1108]	2	hSpCas9	negative selection	9003450
83538076	83538099	9	+	27260156	SU8686	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.25661286390582916	[176]	[173,203,168,309]	4	hSpCas9	negative selection	9003451
83538142	83538165	9	+	27260156	SKES1	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.008914638461694602	[665]	[583,942,604,568]	0	hSpCas9	negative selection	9060438
83538114	83538137	9	-	27260156	SKES1	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.14851061183421488	[850]	[1159,922,953,765]	3	hSpCas9	negative selection	9060439
83389621	83389644	9	-	27260156	SKES1	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.13287458703214033	[468]	[654,520,380,511]	3	hSpCas9	negative selection	9060440
83389651	83389674	9	-	27260156	SKES1	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	0.06734850252030664	[407]	[663,586,286,239]	1	hSpCas9	negative selection	9124700
83538141	83538164	9	-	27260156	SKES1	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.055876657544932096	[854]	[874,938,964,774]	1	hSpCas9	negative selection	9124701
83538076	83538099	9	+	27260156	SKES1	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.09509204214357392	[176]	[185,176,196,109]	-2	hSpCas9	negative selection	9124702
83538142	83538165	9	+	27260156	TOV112D	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.17565062696017786	[665]	[696,952,808,601]	3	hSpCas9	negative selection	9181689
83538114	83538137	9	-	27260156	TOV112D	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.15733279553883384	[850]	[1033,1277,873,708]	3	hSpCas9	negative selection	9181690
83389621	83389644	9	-	27260156	TOV112D	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5374804978059705	[468]	[789,832,564,586]	8	hSpCas9	negative selection	9181691
83389651	83389674	9	-	27260156	TOV112D	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.07051979566629044	[407]	[358,598,365,283]	-1	hSpCas9	negative selection	9245951
83538141	83538164	9	-	27260156	TOV112D	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	-0.12622056151424765	[854]	[787,971,766,659]	-2	hSpCas9	negative selection	9245952
83538076	83538099	9	+	27260156	TOV112D	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.13255061457303885	[176]	[277,199,132,174]	2	hSpCas9	negative selection	9245953
83538142	83538165	9	+	27260156	TC71	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	-0.18772381691163437	[665]	[678,544,545,745]	-5	hSpCas9	negative selection	9302940
83538114	83538137	9	-	27260156	TC71	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.012872394773914553	[850]	[825,940,965,950]	0	hSpCas9	negative selection	9302941
83389621	83389644	9	-	27260156	TC71	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.29479073517612764	[468]	[594,582,655,632]	7	hSpCas9	negative selection	9302942
83389651	83389674	9	-	27260156	TC71	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.25447913320515503	[407]	[334,424,261,453]	-6	hSpCas9	negative selection	9367202
83538141	83538164	9	-	27260156	TC71	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	-0.13370530561863192	[854]	[783,884,743,938]	-3	hSpCas9	negative selection	9367203
83538076	83538099	9	+	27260156	TC71	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	-0.02771437693875578	[176]	[162,131,196,256]	0	hSpCas9	negative selection	9367204
83538142	83538165	9	+	27260156	TC32	viability	CTGGCTGAGCGATTTGACGCTGG	FRMD3	ENSG00000172159	0.12596935283490196	[665]	[664,559,834,705]	2	hSpCas9	negative selection	9424191
83538114	83538137	9	-	27260156	TC32	viability	GAGATGCACCATCCGGCTGCTGG	FRMD3	ENSG00000172159	0.26697776898378633	[850]	[877,693,1176,1206]	5	hSpCas9	negative selection	9424192
83389621	83389644	9	-	27260156	TC32	viability	CTACTTTGGCATTCGCTATGTGG	FRMD3	ENSG00000172159	0.5076901816008174	[468]	[690,343,919,667]	8	hSpCas9	negative selection	9424193
83389651	83389674	9	-	27260156	TC32	viability	CTGCAACTACTACAGCCTGCTGG	FRMD3	ENSG00000172159	-0.1420213300780497	[407]	[349,262,396,401]	-3	hSpCas9	negative selection	9488453
83538141	83538164	9	-	27260156	TC32	viability	CAGCGTCAAATCGCTCAGCCAGG	FRMD3	ENSG00000172159	0.3154941200183299	[854]	[1019,622,1535,995]	5	hSpCas9	negative selection	9488454
83538076	83538099	9	+	27260156	TC32	viability	CACGCGCACCTGGATGTGGCAGG	FRMD3	ENSG00000172159	0.6539825364546479	[176]	[321,215,285,216]	9	hSpCas9	negative selection	9488455
83267011	83267034	9	-	27869803	HPAFII	viability after 27 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.14392551059999126	[328]	[197,121,NaN]	-1	hSpCas9	negative selection	9606475
83290593	83290616	9	+	27869803	HPAFII	viability after 27 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.21695327144176055	[287]	[210,62,NaN]	-2	hSpCas9	negative selection	9606476
83298742	83298765	9	+	27869803	HPAFII	viability after 27 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	-0.29229636904196155	[190]	[105,61,NaN]	-2	hSpCas9	negative selection	9606477
83310487	83310510	9	-	27869803	HPAFII	viability after 27 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.1594656438047053	[117]	[78,35,NaN]	-1	hSpCas9	negative selection	9606478
83343190	83343213	9	+	27869803	HPAFII	viability after 27 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.2407383396353338	[323]	[245,163,NaN]	2	hSpCas9	negative selection	9606479
83538106	83538129	9	+	27869803	HPAFII	viability after 27 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.43030120511704717	[279]	[277,131,NaN]	3	hSpCas9	negative selection	9606480
83267011	83267034	9	-	27869803	HPAFII	viability after 15 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.12995174355256928	[328]	[451,242,NaN]	-1	hSpCas9	negative selection	9688924
83290593	83290616	9	+	27869803	HPAFII	viability after 15 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.1661407831530551	[287]	[699,127,NaN]	2	hSpCas9	negative selection	9688925
83298742	83298765	9	+	27869803	HPAFII	viability after 15 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	-0.5558755486306669	[190]	[167,121,NaN]	-6	hSpCas9	negative selection	9688926
83310487	83310510	9	-	27869803	HPAFII	viability after 15 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.5070613416912484	[117]	[297,106,NaN]	6	hSpCas9	negative selection	9688927
83343190	83343213	9	+	27869803	HPAFII	viability after 15 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.07565221507978076	[323]	[464,305,NaN]	0	hSpCas9	negative selection	9688928
83538106	83538129	9	+	27869803	HPAFII	viability after 15 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.02704304429092258	[279]	[498,186,NaN]	0	hSpCas9	negative selection	9688929
83267011	83267034	9	-	27869803	ASPC1	viability after 36 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	-0.3418110444470892	[753]	[149,320,155]	-4	hSpCas9	negative selection	9771373
83290593	83290616	9	+	27869803	ASPC1	viability after 36 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.7280433532595488	[700]	[393,330,467]	7	hSpCas9	negative selection	9771374
83298742	83298765	9	+	27869803	ASPC1	viability after 36 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	-0.04889125794660809	[279]	[76,5,175]	0	hSpCas9	negative selection	9771375
83310487	83310510	9	-	27869803	ASPC1	viability after 36 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.15117554439921999	[279]	[136,64,70]	-1	hSpCas9	negative selection	9771376
83343190	83343213	9	+	27869803	ASPC1	viability after 36 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.16088571113238245	[698]	[322,284,224]	1	hSpCas9	negative selection	9771377
83538106	83538129	9	+	27869803	ASPC1	viability after 36 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	1.1263996377255387	[666]	[760,357,444]	9	hSpCas9	negative selection	9771378
83267011	83267034	9	-	27869803	PATU8988S	viability after 35 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.5237472483698191	[822]	[493,458,NaN]	6	hSpCas9	negative selection	9853822
83290593	83290616	9	+	27869803	PATU8988S	viability after 35 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.021192951309303487	[655]	[317,217,NaN]	0	hSpCas9	negative selection	9853823
83298742	83298765	9	+	27869803	PATU8988S	viability after 35 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.10105239749004247	[408]	[253,98,NaN]	1	hSpCas9	negative selection	9853824
83310487	83310510	9	-	27869803	PATU8988S	viability after 35 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	-0.17670268564331626	[368]	[123,138,NaN]	-2	hSpCas9	negative selection	9853825
83343190	83343213	9	+	27869803	PATU8988S	viability after 35 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	-0.023994685310749636	[623]	[321,171,NaN]	0	hSpCas9	negative selection	9853826
83538106	83538129	9	+	27869803	PATU8988S	viability after 35 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.16969068144334865	[580]	[221,193,NaN]	-2	hSpCas9	negative selection	9853827
83267011	83267034	9	-	27869803	PATU8988S	viability after 31 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.08596816228949788	[822]	[324,377,NaN]	1	hSpCas9	negative selection	9936271
83290593	83290616	9	+	27869803	PATU8988S	viability after 31 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.14916265964209396	[655]	[231,363,NaN]	1	hSpCas9	negative selection	9936272
83298742	83298765	9	+	27869803	PATU8988S	viability after 31 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.16241517161253144	[408]	[178,186,NaN]	2	hSpCas9	negative selection	9936273
83310487	83310510	9	-	27869803	PATU8988S	viability after 31 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.04351313261143119	[368]	[159,140,NaN]	0	hSpCas9	negative selection	9936274
83343190	83343213	9	+	27869803	PATU8988S	viability after 31 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.15273887690574692	[623]	[291,256,NaN]	2	hSpCas9	negative selection	9936275
83538106	83538129	9	+	27869803	PATU8988S	viability after 31 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.33131829164730664	[580]	[283,300,NaN]	4	hSpCas9	negative selection	9936276
83267011	83267034	9	-	27869803	HPAFII	viability after 35 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.5281753947166211	[328]	[266,209,NaN]	3	hSpCas9	negative selection	10018720
83290593	83290616	9	+	27869803	HPAFII	viability after 35 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	-0.5874533858295307	[287]	[160,24,NaN]	-4	hSpCas9	negative selection	10018721
83298742	83298765	9	+	27869803	HPAFII	viability after 35 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	-0.2799132309761486	[190]	[65,94,NaN]	-2	hSpCas9	negative selection	10018722
83310487	83310510	9	-	27869803	HPAFII	viability after 35 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.38155414742485116	[117]	[74,80,NaN]	2	hSpCas9	negative selection	10018723
83343190	83343213	9	+	27869803	HPAFII	viability after 35 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.6117587363550163	[323]	[252,247,NaN]	4	hSpCas9	negative selection	10018724
83538106	83538129	9	+	27869803	HPAFII	viability after 35 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	0.4375304192081526	[279]	[246,129,NaN]	3	hSpCas9	negative selection	10018725
83267011	83267034	9	-	27869803	HPAFII	viability after 31 days	AAGGTCACAGCTCGTAACACTGG	FRMD3	ENSG00000172159	0.2659361268219189	[328]	[266,172,NaN]	2	hSpCas9	negative selection	10101169
83290593	83290616	9	+	27869803	HPAFII	viability after 31 days	ACAGACTTACCCTCACCCAGAGG	FRMD3	ENSG00000172159	0.1860557508732322	[287]	[303,52,NaN]	1	hSpCas9	negative selection	10101170
83298742	83298765	9	+	27869803	HPAFII	viability after 31 days	ACTCACCTGTGCACCTCAGGAGG	FRMD3	ENSG00000172159	0.5710272230908517	[190]	[119,201,NaN]	4	hSpCas9	negative selection	10101171
83310487	83310510	9	-	27869803	HPAFII	viability after 31 days	TTATGTGATTGGCACCCAGAAGG	FRMD3	ENSG00000172159	0.3811807019789478	[117]	[102,67,NaN]	2	hSpCas9	negative selection	10101172
83343190	83343213	9	+	27869803	HPAFII	viability after 31 days	CTTGAACAATACAGGCACCCAGG	FRMD3	ENSG00000172159	0.5493846223154699	[323]	[301,226,NaN]	4	hSpCas9	negative selection	10101173
83538106	83538129	9	+	27869803	HPAFII	viability after 31 days	CGAGTCGTCCAGCAGCCGGATGG	FRMD3	ENSG00000172159	-0.26595418380300256	[279]	[212,40,NaN]	-2	hSpCas9	negative selection	10101174
83248052	83248075	9	+	28162770	P31FUJ	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	0.55939291047222	[40]	[70]	6	hSpCas9	negative selection	10158920
83248489	83248512	9	+	28162770	P31FUJ	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.20367246552675677	[500]	[677]	2	hSpCas9	negative selection	10158921
83248454	83248477	9	-	28162770	P31FUJ	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-3.303191532305777	[419]	[49]	-9	hSpCas9	negative selection	10158922
83248326	83248349	9	+	28162770	P31FUJ	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.5763542101239945	[342]	[600]	6	hSpCas9	negative selection	10158923
83248097	83248120	9	+	28162770	P31FUJ	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.4982928016273278	[196]	[326]	5	hSpCas9	negative selection	10158924
83248368	83248391	9	+	28162770	P31FUJ	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.13083614235782087	[149]	[192]	1	hSpCas9	negative selection	10158925
83248202	83248225	9	-	28162770	P31FUJ	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.14621451941828778	[96]	[102]	-1	hSpCas9	negative selection	10158926
83248182	83248205	9	-	28162770	P31FUJ	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.13663132769104336	[465]	[601]	1	hSpCas9	negative selection	10158927
83248443	83248466	9	+	28162770	P31FUJ	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.13523781532729562	[350]	[452]	1	hSpCas9	negative selection	10158928
83248175	83248198	9	+	28162770	P31FUJ	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	0.4192744921653144	[34]	[54]	5	hSpCas9	negative selection	10158929
83248052	83248075	9	+	28162770	TF1	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10328286
83248489	83248512	9	+	28162770	TF1	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	NaN	[NaN]	[591]	1	hSpCas9	negative selection	10328287
83248454	83248477	9	-	28162770	TF1	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10328288
83248326	83248349	9	+	28162770	TF1	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	NaN	[NaN]	[320]	1	hSpCas9	negative selection	10328289
83248097	83248120	9	+	28162770	TF1	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10328290
83248368	83248391	9	+	28162770	TF1	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10328291
83248202	83248225	9	-	28162770	TF1	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10328292
83248182	83248205	9	-	28162770	TF1	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	NaN	[NaN]	[458]	1	hSpCas9	negative selection	10328293
83248443	83248466	9	+	28162770	TF1	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	NaN	[NaN]	[587]	1	hSpCas9	negative selection	10328294
83248175	83248198	9	+	28162770	TF1	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10328295
83248052	83248075	9	+	28162770	SKM1	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	0.7629608026991503	[8]	[26]	7	hSpCas9	negative selection	10497652
83248489	83248512	9	+	28162770	SKM1	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	-0.21056698593965828	[107]	[164]	-2	hSpCas9	negative selection	10497653
83248454	83248477	9	-	28162770	SKM1	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-5.237039197300849	[127]	[5]	-9	hSpCas9	negative selection	10497654
83248326	83248349	9	+	28162770	SKM1	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	1.115937333845743	[94]	[363]	9	hSpCas9	negative selection	10497655
83248097	83248120	9	+	28162770	SKM1	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.25075464441330847	[57]	[121]	2	hSpCas9	negative selection	10497656
83248368	83248391	9	+	28162770	SKM1	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	-0.06992921146559088	[56]	[95]	0	hSpCas9	negative selection	10497657
83248202	83248225	9	-	28162770	SKM1	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.7318038890504275	[30]	[32]	-5	hSpCas9	negative selection	10497658
83248182	83248205	9	-	28162770	SKM1	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.557537120035452	[107]	[280]	5	hSpCas9	negative selection	10497659
83248443	83248466	9	+	28162770	SKM1	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.47823132576603794	[66]	[164]	4	hSpCas9	negative selection	10497660
83248175	83248198	9	+	28162770	SKM1	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	1.7325871536556319	[7]	[46]	9	hSpCas9	negative selection	10497661
83248052	83248075	9	+	28162770	SKM1	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	0.7629608026991503	[8]	[26]	7	hSpCas9	negative selection	10667018
83248489	83248512	9	+	28162770	SKM1	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	-0.21056698593965828	[107]	[164]	-2	hSpCas9	negative selection	10667019
83248454	83248477	9	-	28162770	SKM1	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-5.237039197300849	[127]	[5]	-9	hSpCas9	negative selection	10667020
83248326	83248349	9	+	28162770	SKM1	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	1.115937333845743	[94]	[363]	9	hSpCas9	negative selection	10667021
83248097	83248120	9	+	28162770	SKM1	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.25075464441330847	[57]	[121]	2	hSpCas9	negative selection	10667022
83248368	83248391	9	+	28162770	SKM1	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	-0.06992921146559088	[56]	[95]	0	hSpCas9	negative selection	10667023
83248202	83248225	9	-	28162770	SKM1	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.7318038890504275	[30]	[32]	-5	hSpCas9	negative selection	10667024
83248182	83248205	9	-	28162770	SKM1	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.557537120035452	[107]	[280]	5	hSpCas9	negative selection	10667025
83248443	83248466	9	+	28162770	SKM1	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.47823132576603794	[66]	[164]	4	hSpCas9	negative selection	10667026
83248175	83248198	9	+	28162770	SKM1	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	1.7325871536556319	[7]	[46]	9	hSpCas9	negative selection	10667027
83248052	83248075	9	+	28162770	PL21	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	1.740707995852023	[43]	[63]	9	hSpCas9	negative selection	10836384
83248489	83248512	9	+	28162770	PL21	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	-0.01583796728369946	[373]	[160]	0	hSpCas9	negative selection	10836385
83248454	83248477	9	-	28162770	PL21	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-1.9632276709308298	[438]	[48]	-8	hSpCas9	negative selection	10836386
83248326	83248349	9	+	28162770	PL21	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.275044423503211	[318]	[167]	2	hSpCas9	negative selection	10836387
83248097	83248120	9	+	28162770	PL21	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	-0.16525650897415162	[218]	[84]	-1	hSpCas9	negative selection	10836388
83248368	83248391	9	+	28162770	PL21	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.4955954980154915	[175]	[107]	4	hSpCas9	negative selection	10836389
83248202	83248225	9	-	28162770	PL21	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	1.3830036716391307	[73]	[83]	9	hSpCas9	negative selection	10836390
83248182	83248205	9	-	28162770	PL21	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	1.0097575880554932	[363]	[318]	8	hSpCas9	negative selection	10836391
83248443	83248466	9	+	28162770	PL21	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	1.304981980346818	[198]	[213]	9	hSpCas9	negative selection	10836392
83248175	83248198	9	+	28162770	PL21	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	-2.0728788799170963	[28]	[2]	-8	hSpCas9	negative selection	10836393
83248052	83248075	9	+	28162770	P31FUJ	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	0.55939291047222	[40]	[70]	6	hSpCas9	negative selection	11005750
83248489	83248512	9	+	28162770	P31FUJ	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.20367246552675677	[500]	[677]	2	hSpCas9	negative selection	11005751
83248454	83248477	9	-	28162770	P31FUJ	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-3.303191532305777	[419]	[49]	-9	hSpCas9	negative selection	11005752
83248326	83248349	9	+	28162770	P31FUJ	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.5763542101239945	[342]	[600]	6	hSpCas9	negative selection	11005753
83248097	83248120	9	+	28162770	P31FUJ	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.4982928016273278	[196]	[326]	5	hSpCas9	negative selection	11005754
83248368	83248391	9	+	28162770	P31FUJ	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.13083614235782087	[149]	[192]	1	hSpCas9	negative selection	11005755
83248202	83248225	9	-	28162770	P31FUJ	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.14621451941828778	[96]	[102]	-1	hSpCas9	negative selection	11005756
83248182	83248205	9	-	28162770	P31FUJ	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.13663132769104336	[465]	[601]	1	hSpCas9	negative selection	11005757
83248443	83248466	9	+	28162770	P31FUJ	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.13523781532729562	[350]	[452]	1	hSpCas9	negative selection	11005758
83248175	83248198	9	+	28162770	P31FUJ	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	0.4192744921653144	[34]	[54]	5	hSpCas9	negative selection	11005759
83248052	83248075	9	+	28162770	OCIAML5	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	1.271315844641285	[13]	[60]	9	hSpCas9	negative selection	11175116
83248489	83248512	9	+	28162770	OCIAML5	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.907535219745239	[214]	[727]	7	hSpCas9	negative selection	11175117
83248454	83248477	9	-	28162770	OCIAML5	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-2.1859673074174353	[241]	[95]	-8	hSpCas9	negative selection	11175118
83248326	83248349	9	+	28162770	OCIAML5	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	-0.035512711959928334	[267]	[471]	0	hSpCas9	negative selection	11175119
83248097	83248120	9	+	28162770	OCIAML5	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	-0.21020167890836372	[115]	[180]	-1	hSpCas9	negative selection	11175120
83248368	83248391	9	+	28162770	OCIAML5	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.8862099684545562	[109]	[366]	7	hSpCas9	negative selection	11175121
83248202	83248225	9	-	28162770	OCIAML5	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.9242163566198324	[81]	[77]	-5	hSpCas9	negative selection	11175122
83248182	83248205	9	-	28162770	OCIAML5	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.29315798994999076	[287]	[636]	2	hSpCas9	negative selection	11175123
83248443	83248466	9	+	28162770	OCIAML5	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.6781034570167799	[160]	[464]	6	hSpCas9	negative selection	11175124
83248175	83248198	9	+	28162770	OCIAML5	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	1.4698615240233655	[3]	[19]	9	hSpCas9	negative selection	11175125
83248052	83248075	9	+	28162770	EOL1	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	0.783191922324993	[74]	[67]	7	hSpCas9	negative selection	11344482
83248489	83248512	9	+	28162770	EOL1	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.4357462176196363	[427]	[304]	4	hSpCas9	negative selection	11344483
83248454	83248477	9	-	28162770	EOL1	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-2.5450940456689812	[708]	[63]	-8	hSpCas9	negative selection	11344484
83248326	83248349	9	+	28162770	EOL1	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.5348415622483123	[620]	[473]	5	hSpCas9	negative selection	11344485
83248097	83248120	9	+	28162770	EOL1	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.4005280350746851	[393]	[273]	3	hSpCas9	negative selection	11344486
83248368	83248391	9	+	28162770	EOL1	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	-0.08883125823066537	[324]	[160]	0	hSpCas9	negative selection	11344487
83248202	83248225	9	-	28162770	EOL1	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	0.9864755207137366	[113]	[118]	8	hSpCas9	negative selection	11344488
83248182	83248205	9	-	28162770	EOL1	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.6305367504995212	[498]	[406]	5	hSpCas9	negative selection	11344489
83248443	83248466	9	+	28162770	EOL1	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	-0.39934183965011383	[367]	[146]	-3	hSpCas9	negative selection	11344490
83248175	83248198	9	+	28162770	EOL1	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	-0.699943093337259	[36]	[11]	-5	hSpCas9	negative selection	11344491
83248052	83248075	9	+	28162770	MOLM13	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	1.1199660781242717	[62]	[98]	8	hSpCas9	negative selection	11513848
83248489	83248512	9	+	28162770	MOLM13	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.830459460929287	[552]	[710]	6	hSpCas9	negative selection	11513849
83248454	83248477	9	-	28162770	MOLM13	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-4.11484501828446	[646]	[26]	-9	hSpCas9	negative selection	11513850
83248326	83248349	9	+	28162770	MOLM13	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.957450666366264	[447]	[628]	7	hSpCas9	negative selection	11513851
83248097	83248120	9	+	28162770	MOLM13	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	1.0091039869005674	[278]	[405]	7	hSpCas9	negative selection	11513852
83248368	83248391	9	+	28162770	MOLM13	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.8903443523859057	[290]	[389]	6	hSpCas9	negative selection	11513853
83248202	83248225	9	-	28162770	MOLM13	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	0.29385998176953	[131]	[116]	2	hSpCas9	negative selection	11513854
83248182	83248205	9	-	28162770	MOLM13	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.7122194489194433	[633]	[750]	5	hSpCas9	negative selection	11513855
83248443	83248466	9	+	28162770	MOLM13	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	-0.6925752906486673	[417]	[186]	-4	hSpCas9	negative selection	11513856
83248175	83248198	9	+	28162770	MOLM13	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	-0.4707100737912775	[22]	[11]	-3	hSpCas9	negative selection	11513857
83248052	83248075	9	+	28162770	HEL	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	0.7207413440016301	[53]	[56]	6	hSpCas9	negative selection	11683214
83248489	83248512	9	+	28162770	HEL	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.7126628494407323	[442]	[464]	6	hSpCas9	negative selection	11683215
83248454	83248477	9	-	28162770	HEL	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-3.5491287223226324	[529]	[28]	-9	hSpCas9	negative selection	11683216
83248326	83248349	9	+	28162770	HEL	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	1.1124087802670632	[433]	[600]	8	hSpCas9	negative selection	11683217
83248097	83248120	9	+	28162770	HEL	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.37327815700712996	[269]	[223]	3	hSpCas9	negative selection	11683218
83248368	83248391	9	+	28162770	HEL	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.020495315199741237	[293]	[190]	0	hSpCas9	negative selection	11683219
83248202	83248225	9	-	28162770	HEL	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	0.10337319771931153	[108]	[74]	0	hSpCas9	negative selection	11683220
83248182	83248205	9	-	28162770	HEL	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.09402289748954384	[451]	[308]	0	hSpCas9	negative selection	11683221
83248443	83248466	9	+	28162770	HEL	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.7153425809571969	[309]	[325]	6	hSpCas9	negative selection	11683222
83248175	83248198	9	+	28162770	HEL	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	-1.4447240092499825	[33]	[7]	-7	hSpCas9	negative selection	11683223
83248052	83248075	9	+	28162770	MV411	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	0.49136313366886464	[37]	[44]	4	hSpCas9	negative selection	11852580
83248489	83248512	9	+	28162770	MV411	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.44008262872517123	[328]	[375]	4	hSpCas9	negative selection	11852581
83248454	83248477	9	-	28162770	MV411	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-2.541616554531885	[469]	[67]	-8	hSpCas9	negative selection	11852582
83248326	83248349	9	+	28162770	MV411	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.3218399411807965	[358]	[377]	3	hSpCas9	negative selection	11852583
83248097	83248120	9	+	28162770	MV411	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	1.1095354374348114	[180]	[328]	8	hSpCas9	negative selection	11852584
83248368	83248391	9	+	28162770	MV411	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	1.099538855670462	[194]	[351]	8	hSpCas9	negative selection	11852585
83248202	83248225	9	-	28162770	MV411	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.9341692557071724	[92]	[40]	-6	hSpCas9	negative selection	11852586
83248182	83248205	9	-	28162770	MV411	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	-0.07177445599600407	[397]	[318]	0	hSpCas9	negative selection	11852587
83248443	83248466	9	+	28162770	MV411	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	0.010603617057841686	[250]	[212]	0	hSpCas9	negative selection	11852588
83248175	83248198	9	+	28162770	MV411	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	1.8719284156905687	[11]	[36]	9	hSpCas9	negative selection	11852589
83248052	83248075	9	+	28162770	MONOMAC1	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	-1.2844996883098931	[33]	[15]	-7	hSpCas9	negative selection	12021946
83248489	83248512	9	+	28162770	MONOMAC1	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	-0.1709240067404224	[218]	[222]	-1	hSpCas9	negative selection	12021947
83248454	83248477	9	-	28162770	MONOMAC1	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-1.5246115050880582	[255]	[101]	-8	hSpCas9	negative selection	12021948
83248326	83248349	9	+	28162770	MONOMAC1	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.34195979970942214	[286]	[416]	3	hSpCas9	negative selection	12021949
83248097	83248120	9	+	28162770	MONOMAC1	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	-0.44639631599627105	[125]	[105]	-4	hSpCas9	negative selection	12021950
83248368	83248391	9	+	28162770	MONOMAC1	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	0.006496547025578295	[131]	[151]	0	hSpCas9	negative selection	12021951
83248202	83248225	9	-	28162770	MONOMAC1	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	1.043971252444241	[43]	[103]	8	hSpCas9	negative selection	12021952
83248182	83248205	9	-	28162770	MONOMAC1	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.010451567339242018	[277]	[320]	0	hSpCas9	negative selection	12021953
83248443	83248466	9	+	28162770	MONOMAC1	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	1.297727844690024	[120]	[340]	9	hSpCas9	negative selection	12021954
83248175	83248198	9	+	28162770	MONOMAC1	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	0.9284940350243052	[21]	[47]	8	hSpCas9	negative selection	12021955
83248052	83248075	9	+	28162770	OCIAML2	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	-0.8856673245210049	[7]	[23]	-6	hSpCas9	negative selection	12191312
83248489	83248512	9	+	28162770	OCIAML2	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.7772976882014242	[57]	[550]	7	hSpCas9	negative selection	12191313
83248454	83248477	9	-	28162770	OCIAML2	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-3.0747011489110223	[75]	[49]	-9	hSpCas9	negative selection	12191314
83248326	83248349	9	+	28162770	OCIAML2	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.23141735272081665	[68]	[448]	2	hSpCas9	negative selection	12191315
83248097	83248120	9	+	28162770	OCIAML2	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.6039171281228929	[32]	[277]	6	hSpCas9	negative selection	12191316
83248368	83248391	9	+	28162770	OCIAML2	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	1.0586232428927074	[32]	[380]	8	hSpCas9	negative selection	12191317
83248202	83248225	9	-	28162770	OCIAML2	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-0.5798588949969197	[23]	[88]	-4	hSpCas9	negative selection	12191318
83248182	83248205	9	-	28162770	OCIAML2	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.22856242629211998	[88]	[577]	2	hSpCas9	negative selection	12191319
83248443	83248466	9	+	28162770	OCIAML2	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	1.1255599309022493	[31]	[386]	9	hSpCas9	negative selection	12191320
83248175	83248198	9	+	28162770	OCIAML2	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	-0.4117361361885927	[5]	[24]	-3	hSpCas9	negative selection	12191321
83248052	83248075	9	+	28162770	OCIAML3	viability	TACCTGACTCCAAAAGGAGGAGG	FRMD3	ENSG00000172159	-0.22477383065844414	[11]	[30]	-2	hSpCas9	negative selection	12360678
83248489	83248512	9	+	28162770	OCIAML3	viability	ATGTTCTCCTCTTTAGGCAATGG	FRMD3	ENSG00000172159	0.26771298484998973	[92]	[337]	2	hSpCas9	negative selection	12360679
83248454	83248477	9	-	28162770	OCIAML3	viability	GATCTCCAGCTCCCCAGTGAAGG	FRMD3	ENSG00000172159	-2.7390579731274465	[114]	[51]	-9	hSpCas9	negative selection	12360680
83248326	83248349	9	+	28162770	OCIAML3	viability	CTCATCGTCATCCACAGGGGTGG	FRMD3	ENSG00000172159	0.7045459461893904	[111]	[550]	6	hSpCas9	negative selection	12360681
83248097	83248120	9	+	28162770	OCIAML3	viability	GCAGTCCCAGGCCCACCACAAGG	FRMD3	ENSG00000172159	0.38214561772146916	[60]	[239]	3	hSpCas9	negative selection	12360682
83248368	83248391	9	+	28162770	OCIAML3	viability	GTTGTACACTAGTTCAGAGATGG	FRMD3	ENSG00000172159	-1.5051983733663072	[62]	[66]	-8	hSpCas9	negative selection	12360683
83248202	83248225	9	-	28162770	OCIAML3	viability	TGAAGAAGAGGAGCTGAAGGAGG	FRMD3	ENSG00000172159	-1.6335360045108005	[36]	[35]	-8	hSpCas9	negative selection	12360684
83248182	83248205	9	-	28162770	OCIAML3	viability	AGGCTCGCCGTGCTTTGTCGTGG	FRMD3	ENSG00000172159	0.7704037858847126	[86]	[447]	7	hSpCas9	negative selection	12360685
83248443	83248466	9	+	28162770	OCIAML3	viability	CTCCCGGGCTGCCTTCACTGGGG	FRMD3	ENSG00000172159	1.0066364826292626	[60]	[369]	8	hSpCas9	negative selection	12360686
83248175	83248198	9	+	28162770	OCIAML3	viability	CATAGCTCCACGACAAAGCACGG	FRMD3	ENSG00000172159	-2.1085808131539214	[9]	[6]	-8	hSpCas9	negative selection	12360687