Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2487
• Symbol:FRZB
• Description:frizzled related protein

DataSource: http://genomecrispr.dkfz.de/#!/results/FRZB

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
182866478	182866501	2	+	26472758	Jiyoye	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.5611157587667885	[89]	[45]	-4	hSpCas9	negative selection	60080
182866099	182866122	2	-	26472758	Jiyoye	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.2028781001781133	[173]	[113]	-1	hSpCas9	negative selection	60081
182866120	182866143	2	-	26472758	Jiyoye	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.44859530888585414	[102]	[105]	3	hSpCas9	negative selection	60082
182866509	182866532	2	-	26472758	Jiyoye	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	1.6366572276286409	[28]	[67]	8	hSpCas9	negative selection	60083
182866409	182866432	2	+	26472758	Jiyoye	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	1.1375683217485932	[43]	[72]	7	hSpCas9	negative selection	60084
182866153	182866176	2	+	26472758	Jiyoye	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.12560502423465195	[140]	[115]	1	hSpCas9	negative selection	60085
182838493	182838516	2	+	26472758	Jiyoye	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	2.11412840660564	[33]	[110]	9	hSpCas9	negative selection	60086
182866343	182866366	2	+	26472758	Jiyoye	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	-0.55805920033345	[163]	[83]	-4	hSpCas9	negative selection	60087
182866298	182866321	2	+	26472758	Jiyoye	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.45196208265427706	[77]	[42]	-3	hSpCas9	negative selection	60088
182866288	182866311	2	+	26472758	Jiyoye	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.18760900424818883	[84]	[72]	1	hSpCas9	negative selection	60089
182866478	182866501	2	+	26472758	KBM7	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.1830938888180276	[813,414]	[120,125]	-7	hSpCas9	negative selection	251198
182866099	182866122	2	-	26472758	KBM7	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.9667761433826713	[364,314]	[214,397]	9	hSpCas9	negative selection	251199
182866120	182866143	2	-	26472758	KBM7	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.3837519543422378	[544,326]	[215,302]	4	hSpCas9	negative selection	251200
182866509	182866532	2	-	26472758	KBM7	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	-0.5418315616715819	[152,75]	[37,33]	-5	hSpCas9	negative selection	251201
182866409	182866432	2	+	26472758	KBM7	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	0.37220930661029883	[178,212]	[112,127]	4	hSpCas9	negative selection	251202
182866153	182866176	2	+	26472758	KBM7	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.31844734533539437	[412,475]	[352,183]	3	hSpCas9	negative selection	251203
182838493	182838516	2	+	26472758	KBM7	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.6468288829777047	[292,260]	[161,240]	7	hSpCas9	negative selection	251204
182866343	182866366	2	+	26472758	KBM7	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.5136144162537969	[511,402]	[184,411]	5	hSpCas9	negative selection	251205
182866298	182866321	2	+	26472758	KBM7	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.2635969839087029	[233,378]	[103,140]	-3	hSpCas9	negative selection	251206
182866288	182866311	2	+	26472758	KBM7	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.16730708272631983	[244,345]	[130,184]	1	hSpCas9	negative selection	251207
182866478	182866501	2	+	26472758	Raji	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.5835124100966218	[225]	[34]	-5	hSpCas9	negative selection	442316
182866099	182866122	2	-	26472758	Raji	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.01716156256470386	[265]	[60]	0	hSpCas9	negative selection	442317
182866120	182866143	2	-	26472758	Raji	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.0030468755588638208	[214]	[49]	0	hSpCas9	negative selection	442318
182866509	182866532	2	-	26472758	Raji	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	3.107383535373599	[13]	[27]	9	hSpCas9	negative selection	442319
182866409	182866432	2	+	26472758	Raji	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	-0.6516083651226054	[87]	[12]	-5	hSpCas9	negative selection	442320
182866153	182866176	2	+	26472758	Raji	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.3173066047478309	[248]	[71]	3	hSpCas9	negative selection	442321
182838493	182838516	2	+	26472758	Raji	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.2062769435301624	[173]	[34]	-2	hSpCas9	negative selection	442322
182866343	182866366	2	+	26472758	Raji	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.16878408003774267	[252]	[65]	1	hSpCas9	negative selection	442323
182866298	182866321	2	+	26472758	Raji	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-1.2501684692444843	[163]	[15]	-7	hSpCas9	negative selection	442324
182866288	182866311	2	+	26472758	Raji	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.21208091404029283	[185]	[49]	2	hSpCas9	negative selection	442325
182866478	182866501	2	+	26472758	K562	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.6970290899784402	[337]	[87]	-7	hSpCas9	negative selection	633434
182866099	182866122	2	-	26472758	K562	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.04648247160029101	[344]	[281]	0	hSpCas9	negative selection	633435
182866120	182866143	2	-	26472758	K562	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	1.1073992485581567	[297]	[541]	8	hSpCas9	negative selection	633436
182866509	182866532	2	-	26472758	K562	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	0.8142743359973947	[63]	[94]	6	hSpCas9	negative selection	633437
182866409	182866432	2	+	26472758	K562	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	-0.8086926087931152	[82]	[39]	-5	hSpCas9	negative selection	633438
182866153	182866176	2	+	26472758	K562	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.7031488169726883	[373]	[513]	6	hSpCas9	negative selection	633439
182838493	182838516	2	+	26472758	K562	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.11197277678913686	[232]	[181]	-1	hSpCas9	negative selection	633440
182866343	182866366	2	+	26472758	K562	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	1.289248509127226	[300]	[620]	9	hSpCas9	negative selection	633441
182866298	182866321	2	+	26472758	K562	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-1.2784828049224577	[272]	[94]	-6	hSpCas9	negative selection	633442
182866288	182866311	2	+	26472758	K562	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.18727482056283803	[308]	[296]	1	hSpCas9	negative selection	633443
182838493	182838516	2	+	26627737	DLD1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.16354504877745552	[561]	[130,216,236]	1	hSpCas9	negative selection	809551
182838510	182838533	2	+	26627737	DLD1	viability	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.7382697735929793	[837]	[478,491,354]	7	hSpCas9	negative selection	809552
182866076	182866099	2	+	26627737	DLD1	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.9608199112078059	[1296]	[174,321,142]	-7	hSpCas9	negative selection	809553
182866099	182866122	2	-	26627737	DLD1	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	1.271282485208955	[105]	[64,27,135]	9	hSpCas9	negative selection	809554
182866150	182866173	2	-	26627737	DLD1	viability	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.5985311092560095	[623]	[361,318,217]	6	hSpCas9	negative selection	809555
182866396	182866419	2	+	26627737	DLD1	viability	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.8326191873267603	[376]	[176,254,200]	7	hSpCas9	negative selection	809556
182838493	182838516	2	+	26627737	GBM cells	viability after 5 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.17079509692571887	[211]	[103,97]	-3	hSpCas9	negative selection	891866
182838510	182838533	2	+	26627737	GBM cells	viability after 5 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.13750742145618045	[505]	[359,236]	2	hSpCas9	negative selection	891867
182866076	182866099	2	+	26627737	GBM cells	viability after 5 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.24579113656734974	[481]	[161,273]	-4	hSpCas9	negative selection	891868
182866099	182866122	2	-	26627737	GBM cells	viability after 5 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.16248666977845772	[95]	[47,43]	-3	hSpCas9	negative selection	891869
182866150	182866173	2	-	26627737	GBM cells	viability after 5 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.8247017700868068	[358]	[284,396]	9	hSpCas9	negative selection	891870
182866396	182866419	2	+	26627737	GBM cells	viability after 5 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	-0.04899761396586015	[271]	[144,136]	0	hSpCas9	negative selection	891871
182838493	182838516	2	+	26627737	GBM cells	viability after 13 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.949395880070437	[211]	[90,33]	-8	hSpCas9	negative selection	974181
182838510	182838533	2	+	26627737	GBM cells	viability after 13 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.13195367789395784	[505]	[323,281]	1	hSpCas9	negative selection	974182
182866076	182866099	2	+	26627737	GBM cells	viability after 13 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.001661414758073465	[481]	[290,236]	0	hSpCas9	negative selection	974183
182866099	182866122	2	-	26627737	GBM cells	viability after 13 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.27845605959236464	[95]	[71,55]	3	hSpCas9	negative selection	974184
182866150	182866173	2	-	26627737	GBM cells	viability after 13 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	1.0057761546378896	[358]	[453,339]	9	hSpCas9	negative selection	974185
182866396	182866419	2	+	26627737	GBM cells	viability after 13 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.3868774468470183	[271]	[203,183]	5	hSpCas9	negative selection	974186
182838493	182838516	2	+	26627737	GBM cells	viability after 21 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.2818869113132791	[211]	[100,88]	-3	hSpCas9	negative selection	1056496
182838510	182838533	2	+	26627737	GBM cells	viability after 21 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.4342423630964394	[505]	[407,337]	4	hSpCas9	negative selection	1056497
182866076	182866099	2	+	26627737	GBM cells	viability after 21 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.05839728393745969	[481]	[291,254]	0	hSpCas9	negative selection	1056498
182866099	182866122	2	-	26627737	GBM cells	viability after 21 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-1.0583104972629516	[95]	[23,25]	-7	hSpCas9	negative selection	1056499
182866150	182866173	2	-	26627737	GBM cells	viability after 21 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.24975227555124835	[358]	[245,218]	2	hSpCas9	negative selection	1056500
182866396	182866419	2	+	26627737	GBM cells	viability after 21 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.6951120720550752	[271]	[256,222]	7	hSpCas9	negative selection	1056501
182838493	182838516	2	+	26627737	RPE1	viability after 9 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.4448854343860158	[1240]	[153,454]	-3	hSpCas9	negative selection	1138811
182838510	182838533	2	+	26627737	RPE1	viability after 9 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.4267062827091985	[1809]	[817,688]	3	hSpCas9	negative selection	1138812
182866076	182866099	2	+	26627737	RPE1	viability after 9 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.08132747043758848	[1256]	[319,438]	0	hSpCas9	negative selection	1138813
182866099	182866122	2	-	26627737	RPE1	viability after 9 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.9005007147254926	[72]	[29,58]	6	hSpCas9	negative selection	1138814
182866150	182866173	2	-	26627737	RPE1	viability after 9 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.3691283346489804	[1741]	[768,620]	2	hSpCas9	negative selection	1138815
182866396	182866419	2	+	26627737	RPE1	viability after 9 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	-0.0812475240055564	[1026]	[292,317]	0	hSpCas9	negative selection	1138816
182838493	182838516	2	+	26627737	RPE1	viability after 12 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-1.0001893345040076	[1240]	[53,285]	-6	hSpCas9	negative selection	1221126
182838510	182838533	2	+	26627737	RPE1	viability after 12 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.2315399800531941	[1809]	[687,446]	1	hSpCas9	negative selection	1221127
182866076	182866099	2	+	26627737	RPE1	viability after 12 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.43576131772811044	[1256]	[449,463]	3	hSpCas9	negative selection	1221128
182866099	182866122	2	-	26627737	RPE1	viability after 12 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.5882310912714082	[72]	[11,47]	4	hSpCas9	negative selection	1221129
182866150	182866173	2	-	26627737	RPE1	viability after 12 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.15305965490470652	[1741]	[601,433]	1	hSpCas9	negative selection	1221130
182866396	182866419	2	+	26627737	RPE1	viability after 12 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	-0.10168278548562415	[1026]	[329,179]	0	hSpCas9	negative selection	1221131
182838493	182838516	2	+	26627737	RPE1	viability after 15 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.9105303991385438	[1240]	[87,281]	-5	hSpCas9	negative selection	1303441
182838510	182838533	2	+	26627737	RPE1	viability after 15 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.8569003234022641	[1809]	[1302,564]	5	hSpCas9	negative selection	1303442
182866076	182866099	2	+	26627737	RPE1	viability after 15 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.07020792410690335	[1256]	[299,375]	0	hSpCas9	negative selection	1303443
182866099	182866122	2	-	26627737	RPE1	viability after 15 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	1.4214505836361944	[72]	[93,17]	7	hSpCas9	negative selection	1303444
182866150	182866173	2	-	26627737	RPE1	viability after 15 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.2724046160173259	[1741]	[809,387]	1	hSpCas9	negative selection	1303445
182866396	182866419	2	+	26627737	RPE1	viability after 15 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.41340606640414995	[1026]	[475,300]	2	hSpCas9	negative selection	1303446
182838493	182838516	2	+	26627737	RPE1	viability after 18 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.5380621044768091	[1240]	[30,443]	-3	hSpCas9	negative selection	1385756
182838510	182838533	2	+	26627737	RPE1	viability after 18 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.6445084718015608	[1809]	[1056,449]	4	hSpCas9	negative selection	1385757
182866076	182866099	2	+	26627737	RPE1	viability after 18 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.028386422187002158	[1256]	[233,437]	0	hSpCas9	negative selection	1385758
182866099	182866122	2	-	26627737	RPE1	viability after 18 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	1.7270422053166572	[72]	[56,73]	8	hSpCas9	negative selection	1385759
182866150	182866173	2	-	26627737	RPE1	viability after 18 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	-0.14729628051155408	[1741]	[525,315]	-1	hSpCas9	negative selection	1385760
182866396	182866419	2	+	26627737	RPE1	viability after 18 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	-0.539165308309172	[1026]	[211,167]	-3	hSpCas9	negative selection	1385761
182838493	182838516	2	+	26627737	HeLa	viability after 8 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.20095909982163268	[349]	[109,156,125]	-2	hSpCas9	negative selection	1468071
182838510	182838533	2	+	26627737	HeLa	viability after 8 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	-0.3763690510331308	[1017]	[204,376,406]	-4	hSpCas9	negative selection	1468072
182866076	182866099	2	+	26627737	HeLa	viability after 8 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.30005520518859874	[601]	[371,247,355]	3	hSpCas9	negative selection	1468073
182866099	182866122	2	-	26627737	HeLa	viability after 8 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-4.0745084612778815	[272]	[17,4,0]	-9	hSpCas9	negative selection	1468074
182866150	182866173	2	-	26627737	HeLa	viability after 8 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.3780504165623941	[432]	[428,158,190]	3	hSpCas9	negative selection	1468075
182866396	182866419	2	+	26627737	HeLa	viability after 8 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.4305423215434076	[273]	[301,136,79]	4	hSpCas9	negative selection	1468076
182838493	182838516	2	+	26627737	HeLa	viability after 12 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.40289411269570397	[349]	[239,50,298]	3	hSpCas9	negative selection	1550386
182838510	182838533	2	+	26627737	HeLa	viability after 12 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	-0.49974731997384003	[1017]	[71,297,515]	-4	hSpCas9	negative selection	1550387
182866076	182866099	2	+	26627737	HeLa	viability after 12 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.0285379352296129	[601]	[113,252,359]	0	hSpCas9	negative selection	1550388
182866099	182866122	2	-	26627737	HeLa	viability after 12 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.6129555295272644	[272]	[120,32,72]	-5	hSpCas9	negative selection	1550389
182866150	182866173	2	-	26627737	HeLa	viability after 12 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	1.3050497766231939	[432]	[626,317,399]	8	hSpCas9	negative selection	1550390
182866396	182866419	2	+	26627737	HeLa	viability after 12 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.7335009463222613	[273]	[186,138,243]	6	hSpCas9	negative selection	1550391
182838493	182838516	2	+	26627737	HeLa	viability after 15 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.134035208376224	[349]	[183,72,131]	-1	hSpCas9	negative selection	1632701
182838510	182838533	2	+	26627737	HeLa	viability after 15 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	-0.30513561844293324	[1017]	[313,230,471]	-3	hSpCas9	negative selection	1632702
182866076	182866099	2	+	26627737	HeLa	viability after 15 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.553515187508743	[601]	[236,527,311]	4	hSpCas9	negative selection	1632703
182866099	182866122	2	-	26627737	HeLa	viability after 15 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.036506508704410856	[272]	[189,72,74]	0	hSpCas9	negative selection	1632704
182866150	182866173	2	-	26627737	HeLa	viability after 15 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	1.1274649354468884	[432]	[372,318,469]	7	hSpCas9	negative selection	1632705
182866396	182866419	2	+	26627737	HeLa	viability after 15 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	1.0069359867775582	[273]	[294,231,137]	7	hSpCas9	negative selection	1632706
182838493	182838516	2	+	26627737	HeLa	viability after 18 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.1092011556157042	[349]	[128,58,131]	-1	hSpCas9	negative selection	1715016
182838510	182838533	2	+	26627737	HeLa	viability after 18 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	-0.29390900176124424	[1017]	[211,195,471]	-3	hSpCas9	negative selection	1715017
182866076	182866099	2	+	26627737	HeLa	viability after 18 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.5869879249498289	[601]	[169,443,311]	5	hSpCas9	negative selection	1715018
182866099	182866122	2	-	26627737	HeLa	viability after 18 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.006021286353305233	[272]	[122,57,74]	0	hSpCas9	negative selection	1715019
182866150	182866173	2	-	26627737	HeLa	viability after 18 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	1.0860811328868547	[432]	[233,257,469]	7	hSpCas9	negative selection	1715020
182866396	182866419	2	+	26627737	HeLa	viability after 18 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.9781400370983844	[273]	[186,194,137]	7	hSpCas9	negative selection	1715021
182838493	182838516	2	+	26627737	HCT116	viability after 6 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.9262844266964514	[379]	[293,13]	5	hSpCas9	negative selection	1797331
182838510	182838533	2	+	26627737	HCT116	viability after 6 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.6147985891885244	[1287]	[690,99]	3	hSpCas9	negative selection	1797332
182866076	182866099	2	+	26627737	HCT116	viability after 6 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.14886684506594616	[1019]	[94,171]	-1	hSpCas9	negative selection	1797333
182866099	182866122	2	-	26627737	HCT116	viability after 6 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.1318240162334856	[179]	[1,46]	0	hSpCas9	negative selection	1797334
182866150	182866173	2	-	26627737	HCT116	viability after 6 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	-1.3071680005775068	[928]	[78,47]	-6	hSpCas9	negative selection	1797335
182866396	182866419	2	+	26627737	HCT116	viability after 6 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	-1.701361948287005	[1395]	[100,48]	-7	hSpCas9	negative selection	1797336
182838493	182838516	2	+	26627737	HCT116	viability after 8 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.8412016600979604	[417]	[145,110,128]	-8	hSpCas9	negative selection	1879646
182838510	182838533	2	+	26627737	HCT116	viability after 8 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.45800602426390624	[559]	[413,314,540]	5	hSpCas9	negative selection	1879647
182866076	182866099	2	+	26627737	HCT116	viability after 8 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.46921867614949486	[812]	[320,262,385]	-5	hSpCas9	negative selection	1879648
182866099	182866122	2	-	26627737	HCT116	viability after 8 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.6961188611333029	[111]	[72,86,138]	6	hSpCas9	negative selection	1879649
182866150	182866173	2	-	26627737	HCT116	viability after 8 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	-0.030260942868682528	[524]	[334,250,264]	0	hSpCas9	negative selection	1879650
182866396	182866419	2	+	26627737	HCT116	viability after 8 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.6282240715982818	[257]	[257,272,129]	6	hSpCas9	negative selection	1879651
182838493	182838516	2	+	26627737	HCT116	viability after 9 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	1.25812701387369	[379]	[402,115]	8	hSpCas9	negative selection	1961961
182838510	182838533	2	+	26627737	HCT116	viability after 9 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.634281994295135	[1287]	[711,392]	4	hSpCas9	negative selection	1961962
182866076	182866099	2	+	26627737	HCT116	viability after 9 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.20496734661631544	[1019]	[304,320]	1	hSpCas9	negative selection	1961963
182866099	182866122	2	-	26627737	HCT116	viability after 9 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.7329215693166464	[179]	[43,16]	-5	hSpCas9	negative selection	1961964
182866150	182866173	2	-	26627737	HCT116	viability after 9 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.26348911104628847	[928]	[299,295]	2	hSpCas9	negative selection	1961965
182866396	182866419	2	+	26627737	HCT116	viability after 9 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	-0.4096573702764117	[1395]	[331,239]	-3	hSpCas9	negative selection	1961966
182838493	182838516	2	+	26627737	HCT116	viability after 12 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.4661908948046133	[417]	[129,175,173]	-5	hSpCas9	negative selection	2044276
182838510	182838533	2	+	26627737	HCT116	viability after 12 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.1360584121782099	[559]	[359,323,282]	1	hSpCas9	negative selection	2044277
182866076	182866099	2	+	26627737	HCT116	viability after 12 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.4285138527139616	[812]	[360,376,211]	-4	hSpCas9	negative selection	2044278
182866099	182866122	2	-	26627737	HCT116	viability after 12 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.3165501775102968	[111]	[55,55,108]	3	hSpCas9	negative selection	2044279
182866150	182866173	2	-	26627737	HCT116	viability after 12 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.2711786765180012	[524]	[303,315,380]	2	hSpCas9	negative selection	2044280
182866396	182866419	2	+	26627737	HCT116	viability after 12 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.9595089799663293	[257]	[266,316,207]	7	hSpCas9	negative selection	2044281
182838493	182838516	2	+	26627737	HCT116	viability after 15 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.9341935850683732	[417]	[131,147,97]	-7	hSpCas9	negative selection	2126591
182838510	182838533	2	+	26627737	HCT116	viability after 15 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.2935267961452154	[559]	[356,510,310]	3	hSpCas9	negative selection	2126592
182866076	182866099	2	+	26627737	HCT116	viability after 15 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.9025265307984793	[812]	[256,227,264]	-7	hSpCas9	negative selection	2126593
182866099	182866122	2	-	26627737	HCT116	viability after 15 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.4186683886819276	[111]	[116,82,61]	4	hSpCas9	negative selection	2126594
182866150	182866173	2	-	26627737	HCT116	viability after 15 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.4356466227401151	[524]	[373,332,510]	4	hSpCas9	negative selection	2126595
182866396	182866419	2	+	26627737	HCT116	viability after 15 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.8344318966824908	[257]	[308,218,269]	7	hSpCas9	negative selection	2126596
182838493	182838516	2	+	26627737	HCT116	viability after 18 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.9475042815402388	[417]	[173,87,50]	-7	hSpCas9	negative selection	2208906
182838510	182838533	2	+	26627737	HCT116	viability after 18 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.3785471944411848	[559]	[296,501,241]	3	hSpCas9	negative selection	2208907
182866076	182866099	2	+	26627737	HCT116	viability after 18 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.7153647839071716	[812]	[228,244,243]	-6	hSpCas9	negative selection	2208908
182866099	182866122	2	-	26627737	HCT116	viability after 18 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.2773037645387797	[111]	[29,50,52]	-3	hSpCas9	negative selection	2208909
182866150	182866173	2	-	26627737	HCT116	viability after 18 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.25736300839383686	[524]	[272,239,405]	2	hSpCas9	negative selection	2208910
182866396	182866419	2	+	26627737	HCT116	viability after 18 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.7349286231595732	[257]	[198,251,166]	6	hSpCas9	negative selection	2208911
182849151	182849174	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGGGGTGGAGCTTGCAGTGAG	FRZB	ENSG00000162998	-1.0744598948026076	[159,146]	[19,10]	-6	dCas9-VP64	positive selection	2391265
182866896	182866919	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAATTCAGCTGAGAGCTAGTTGG	FRZB	ENSG00000162998	-1.0159267266294318	[638,591]	[49,84]	-6	dCas9-VP64	positive selection	2427928
182866853	182866876	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGGACACGAGAGGAGGCGAGG	FRZB	ENSG00000162998	0.8079050619637623	[78,14]	[27,6]	3	dCas9-VP64	positive selection	2427929
182866934	182866957	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTGTGCGTGATCTAGGGGAGG	FRZB	ENSG00000162998	-0.48082225694014546	[1,24]	[1,0]	-2	dCas9-VP64	positive selection	2427930
182849076	182849099	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATTAGCCGGGCGTGGTGGCAAG	FRZB	ENSG00000162998	0.43464799396045883	[0,13]	[2,0]	2	dCas9-VP64	positive selection	2460812
182849151	182849174	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGGGGTGGAGCTTGCAGTGAG	FRZB	ENSG00000162998	-1.662941440906227	[20,166]	[5,11]	-9	dCas9-VP64	positive selection	2486520
182866896	182866919	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAATTCAGCTGAGAGCTAGTTGG	FRZB	ENSG00000162998	-0.9397559982436408	[423,325]	[83,44]	-8	dCas9-VP64	positive selection	2523183
182866853	182866876	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGGACACGAGAGGAGGCGAGG	FRZB	ENSG00000162998	-0.7878349705547492	[390,112]	[54,40]	-7	dCas9-VP64	positive selection	2523184
182866934	182866957	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTGTGCGTGATCTAGGGGAGG	FRZB	ENSG00000162998	0.4076495268688105	[62,29]	[23,15]	3	dCas9-VP64	positive selection	2523185
182849076	182849099	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATTAGCCGGGCGTGGTGGCAAG	FRZB	ENSG00000162998	-0.5732050346504929	[30,53]	[10,6]	-5	dCas9-VP64	positive selection	2556067
182866329	182866352	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.034073213172030326	[2,2]	[3,1]	0	hSpCas9	positive selection	2989365
182866479	182866502	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.14421727072097812	[0,0]	[0,0]	-2	hSpCas9	positive selection	2989366
182866323	182866346	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCAGTTCGAAGGTCTGCTGGG	FRZB	ENSG00000162998	-0.027685300085307105	[3,3]	[2,2]	0	hSpCas9	positive selection	2989367
182866393	182866416	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCATCTTAGTCATGTTCCAGGG	FRZB	ENSG00000162998	0.10894201523029257	[3,4]	[4,2]	2	hSpCas9	positive selection	2989368
182866329	182866352	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.3695443302936171	[2,2]	[3,1]	6	hSpCas9	positive selection	3057223
182866479	182866502	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	0.16525951204222156	[0,0]	[0,0]	3	hSpCas9	positive selection	3057224
182866323	182866346	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCAGTTCGAAGGTCTGCTGGG	FRZB	ENSG00000162998	0.34913872431926934	[3,3]	[5,1]	6	hSpCas9	positive selection	3057225
182866393	182866416	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCATCTTAGTCATGTTCCAGGG	FRZB	ENSG00000162998	0.35615592895433124	[3,3]	[4,2]	6	hSpCas9	positive selection	3057226
182866076	182866099		+	24336571	A375	resistance to PLX after 7 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.202017600112819	[4,8]	[5,6]	-6	hSpCas9	positive selection	3115402
182866211	182866234		+	24336571	A375	resistance to PLX after 7 days	CCGCTCGCACACAGACTTACAGG	FRZB	ENSG00000162998	0.08300134093211908	[8,9]	[9,8]	3	hSpCas9	positive selection	3115403
182866084	182866107		-	24336571	A375	resistance to PLX after 7 days	TCCCGAGGCCATCGTTACTGCGG	FRZB	ENSG00000162998	0.05137319656304218	[20,31]	[23,28]	1	hSpCas9	positive selection	3115405
182858806	182858829		+	24336571	A375	resistance to PLX after 7 days	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.11008983588760063	[8,10]	[9,10]	3	hSpCas9	positive selection	3115406
182866076	182866099		+	24336571	A375	resistance to PLX after 14 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.20821865638266313	[5,4]	[1,1]	-2	hSpCas9	positive selection	3173195
182866211	182866234		+	24336571	A375	resistance to PLX after 14 days	CCGCTCGCACACAGACTTACAGG	FRZB	ENSG00000162998	0.4131462794369444	[6,5]	[4,2]	4	hSpCas9	positive selection	3173196
182866084	182866107		-	24336571	A375	resistance to PLX after 14 days	TCCCGAGGCCATCGTTACTGCGG	FRZB	ENSG00000162998	-0.21063602613263033	[22,26]	[10,8]	-2	hSpCas9	positive selection	3173198
182858806	182858829		+	24336571	A375	resistance to PLX after 14 days	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.26686010984379405	[10,9]	[3,3]	-3	hSpCas9	positive selection	3173199
182866076	182866099		+	24336571	A375	viability after 7 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.0802507390073397	[6]	[4,8]	1	hSpCas9	negative selection	3230988
182866211	182866234		+	24336571	A375	viability after 7 days	CCGCTCGCACACAGACTTACAGG	FRZB	ENSG00000162998	-0.4332162078225907	[12]	[8,9]	-6	hSpCas9	negative selection	3230989
182866084	182866107		-	24336571	A375	viability after 7 days	TCCCGAGGCCATCGTTACTGCGG	FRZB	ENSG00000162998	0.5825905287953738	[17]	[20,31]	8	hSpCas9	negative selection	3230991
182858806	182858829		+	24336571	A375	viability after 7 days	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.6425941316453767	[16]	[8,10]	-7	hSpCas9	negative selection	3230992
182866076	182866099		+	24336571	A375	viability after 14 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.31501164253456626	[6]	[5,4]	-4	hSpCas9	negative selection	3288781
182866211	182866234		+	24336571	A375	viability after 14 days	CCGCTCGCACACAGACTTACAGG	FRZB	ENSG00000162998	-0.9021441950105781	[12]	[6,5]	-8	hSpCas9	negative selection	3288782
182866084	182866107		-	24336571	A375	viability after 14 days	TCCCGAGGCCATCGTTACTGCGG	FRZB	ENSG00000162998	0.5316825018035743	[17]	[22,26]	6	hSpCas9	negative selection	3288784
182858806	182858829		+	24336571	A375	viability after 14 days	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.5070934518376382	[16]	[10,9]	-6	hSpCas9	negative selection	3288785
182866076	182866099	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.23787566350250391	[167,192]	[0,0]	-1	hSpCas9	positive selection	3350584
182866328	182866351	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	1.5622527951223593	[373,298]	[0,11]	6	hSpCas9	positive selection	3350585
182838481	182838504	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	1.0380944079464494	[74,73]	[0,0]	5	hSpCas9	positive selection	3350586
182838493	182838516	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.8997742068277513	[81,81]	[0,0]	4	hSpCas9	positive selection	3369794
182858806	182858829	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.5108581133310913	[217,217]	[0,0]	-3	hSpCas9	positive selection	3369795
182858797	182858820	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	1.9353981165584728	[79,79]	[1,1]	7	hSpCas9	positive selection	3369796
182866328	182866351	2	+	26780180	HT29	viability (Avana library 4 designs)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	1.64611745163464	[]	[]	6	hSpCas9	negative selection	3426316
182866478	182866501	2	+	26780180	HT29	viability (Avana library 4 designs)	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	0.518796570159982	[]	[]	2	hSpCas9	negative selection	3426317
182866323	182866346	2	-	26780180	HT29	viability (Avana library 4 designs)	GAGCAGTTCGAAGGTCTGCTGGG	FRZB	ENSG00000162998	1.37340988792348	[]	[]	5	hSpCas9	negative selection	3426318
182866392	182866415	2	+	26780180	HT29	viability (Avana library 4 designs)	GGCATCTTAGTCATGTTCCAGGG	FRZB	ENSG00000162998	1.40590879312382	[]	[]	5	hSpCas9	negative selection	3426319
182866392	182866415	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCATCTTAGTCATGTTCCAGGG	FRZB	ENSG00000162998	-2.68247765009106	[]	[]	-3	hSpCas9	negative selection	3508920
182866478	182866501	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	2.93716744778053	[]	[]	4	hSpCas9	negative selection	3508921
182866328	182866351	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.032756908756827	[]	[]	0	hSpCas9	negative selection	3508922
182866323	182866346	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCAGTTCGAAGGTCTGCTGGG	FRZB	ENSG00000162998	2.58756828434356	[]	[]	4	hSpCas9	negative selection	3508923
182866080	182866103	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGCCATCGTTACTGCGGACGG	FRZB	ENSG00000162998	2.34021095142414	[]	[]	3	hSpCas9	negative selection	3508924
182866286	182866309	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGAGGAAGAAGAGCAGATCGG	FRZB	ENSG00000162998	1.33236429488858	[]	[]	1	hSpCas9	negative selection	3508925
182866392	182866415	2	+	26780180	A375	viability (Avana lentiGuide)	GGCATCTTAGTCATGTTCCAGGG	FRZB	ENSG00000162998	3.56630325323632	[]	[]	3	hSpCas9	negative selection	3617579
182866478	182866501	2	+	26780180	A375	viability (Avana lentiGuide)	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	7.68696662286347	[]	[]	6	hSpCas9	negative selection	3617580
182866328	182866351	2	+	26780180	A375	viability (Avana lentiGuide)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	1.70449968101375	[]	[]	2	hSpCas9	negative selection	3617581
182866323	182866346	2	-	26780180	A375	viability (Avana lentiGuide)	GAGCAGTTCGAAGGTCTGCTGGG	FRZB	ENSG00000162998	2.65134544653591	[]	[]	3	hSpCas9	negative selection	3617582
182866080	182866103	2	-	26780180	A375	viability (Avana lentiGuide)	GAGGCCATCGTTACTGCGGACGG	FRZB	ENSG00000162998	-0.897682972851452	[]	[]	-1	hSpCas9	negative selection	3617583
182866286	182866309	2	+	26780180	A375	viability (Avana lentiGuide)	ACAGAGGAAGAAGAGCAGATCGG	FRZB	ENSG00000162998	1.26817159053231	[]	[]	1	hSpCas9	negative selection	3617584
182866392	182866415	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCATCTTAGTCATGTTCCAGGG	FRZB	ENSG00000162998	-0.12318302732772231	[5]	[5,4]	-2	hSpCas9	positive selection	3726238
182866478	182866501	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.5805386994817917	[2]	[2,0]	-7	hSpCas9	positive selection	3726239
182866328	182866351	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.054403698526529834	[4]	[5,3]	1	hSpCas9	positive selection	3726240
182866323	182866346	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCAGTTCGAAGGTCTGCTGGG	FRZB	ENSG00000162998	0.3348464916109751	[4]	[5,6]	8	hSpCas9	positive selection	3726241
182866080	182866103	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGCCATCGTTACTGCGGACGG	FRZB	ENSG00000162998	0.3192135841343122	[4]	[6,4]	8	hSpCas9	positive selection	3726242
182866286	182866309	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGAGGAAGAAGAGCAGATCGG	FRZB	ENSG00000162998	-0.11397995955732484	[4]	[4,4]	-2	hSpCas9	positive selection	3726243
182866392	182866415	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCATCTTAGTCATGTTCCAGGG	FRZB	ENSG00000162998	-0.28832024394305633	[5]	[3,4]	-4	hSpCas9	positive selection	3834845
182866478	182866501	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.8872729353097031	[1]	[0,0]	-8	hSpCas9	positive selection	3834846
182866328	182866351	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.0492653176754847	[4]	[2,3]	0	hSpCas9	positive selection	3834847
182866323	182866346	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCAGTTCGAAGGTCTGCTGGG	FRZB	ENSG00000162998	0.31038566944001383	[5]	[5,5]	8	hSpCas9	positive selection	3834848
182866080	182866103	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGCCATCGTTACTGCGGACGG	FRZB	ENSG00000162998	0.16647017544646012	[5]	[4,5]	4	hSpCas9	positive selection	3834849
182866286	182866309	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGAGGAAGAAGAGCAGATCGG	FRZB	ENSG00000162998	-0.07901196107183951	[5]	[4,4]	-1	hSpCas9	positive selection	3834850
182866076	182866099	2	+	26780180	A375	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	1.00653485827047	[]	[]	4	hSpCas9	negative selection	3942014
182866328	182866351	2	+	26780180	A375	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.0467372263328645	[]	[]	-1	hSpCas9	negative selection	3942015
182838481	182838504	2	-	26780180	A375	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	1.15432927172855	[]	[]	6	hSpCas9	negative selection	3942016
182838493	182838516	2	+	26780180	A375	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	1.35800954002178	[]	[]	7	hSpCas9	negative selection	3942017
182858797	182858820	2	-	26780180	A375	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	1.0367282869709	[]	[]	5	hSpCas9	negative selection	3942018
182858806	182858829	2	+	26780180	A375	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	1.36386598454294	[]	[]	7	hSpCas9	negative selection	3942019
182866076	182866099	2	+	26780180	HT29	viability (GeCKOv2 library)	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.743130492664308	[]	[]	3	hSpCas9	negative selection	4049980
182866328	182866351	2	+	26780180	HT29	viability (GeCKOv2 library)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.00925789758771745	[]	[]	0	hSpCas9	negative selection	4049981
182838481	182838504	2	-	26780180	HT29	viability (GeCKOv2 library)	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	1.00724034927001	[]	[]	4	hSpCas9	negative selection	4049982
182838493	182838516	2	+	26780180	HT29	viability (GeCKOv2 library)	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.908133047401487	[]	[]	4	hSpCas9	negative selection	4049983
182858797	182858820	2	-	26780180	HT29	viability (GeCKOv2 library)	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	1.35665050563206	[]	[]	7	hSpCas9	negative selection	4049984
182858806	182858829	2	+	26780180	HT29	viability (GeCKOv2 library)	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.175667949712655	[]	[]	0	hSpCas9	negative selection	4049985
182866076	182866099	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.13648444126158132	[2]	[1,0]	-3	hSpCas9	positive selection	4138493
182866211	182866234	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCTCGCACACAGACTTACAGG	FRZB	ENSG00000162998	-0.0538064093676206	[2]	[1,1]	-1	hSpCas9	positive selection	4138494
182866084	182866107	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCGAGGCCATCGTTACTGCGG	FRZB	ENSG00000162998	0.1409455987909144	[4]	[3,3]	3	hSpCas9	positive selection	4138496
182858806	182858829	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.15005175180864305	[3]	[1,1]	-4	hSpCas9	positive selection	4138497
182866076	182866099	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.766569539271355	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4202515
182866211	182866234	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCTCGCACACAGACTTACAGG	FRZB	ENSG00000162998	1.233710320020212	[3]	[1,2,4,3]	8	hSpCas9	positive selection	4202516
182866084	182866107	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCGAGGCCATCGTTACTGCGG	FRZB	ENSG00000162998	1.1774177699589037	[3]	[3,2,3,4]	8	hSpCas9	positive selection	4202518
182858806	182858829	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.8471244586356057	[4]	[3,0,0,4]	5	hSpCas9	positive selection	4202519
182866076	182866099	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.19952375831044789	[3]	[3,3]	4	hSpCas9	positive selection	4271747
182866328	182866351	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.20387680441515754	[4]	[4,3]	4	hSpCas9	positive selection	4271748
182838481	182838504	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	-0.009095432525061509	[2]	[2,0]	0	hSpCas9	positive selection	4271749
182838493	182838516	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.029495645448327258	[2]	[3,0]	0	hSpCas9	positive selection	4336009
182858806	182858829	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.23930645056911412	[3]	[3,3]	5	hSpCas9	positive selection	4336010
182858797	182858820	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.08226302505692884	[2]	[2,0]	-2	hSpCas9	positive selection	4336011
182866077	182866099	2	+	27760321	OCIAML3	viability	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.1254597570440784	[776,634]	[418,613]	-1	hSpCas9	negative selection	4402132
182866114	182866136	2	+	27760321	OCIAML3	viability	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.25504926021833796	[809,613]	[620,708]	3	hSpCas9	negative selection	4402133
182866163	182866185	2	-	27760321	OCIAML3	viability	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.008624940353435973	[249,238]	[186,199]	0	hSpCas9	negative selection	4402134
182866329	182866351	2	+	27760321	OCIAML3	viability	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	1.0342913669620664	[695,652]	[834,1401]	9	hSpCas9	negative selection	4402135
182866431	182866453	2	+	27760321	OCIAML3	viability	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.5562376561957847	[626,582]	[642,764]	6	hSpCas9	negative selection	4402136
182866077	182866099	2	+	27760321	OCIAML2	viability	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.21102706451032627	[776,634]	[561,783]	2	hSpCas9	negative selection	4485595
182866114	182866136	2	+	27760321	OCIAML2	viability	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	-0.02892263722494881	[809,613]	[493,646]	0	hSpCas9	negative selection	4485596
182866163	182866185	2	-	27760321	OCIAML2	viability	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	-0.12983099221310268	[249,238]	[155,213]	-2	hSpCas9	negative selection	4485597
182866329	182866351	2	+	27760321	OCIAML2	viability	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.25218544398837406	[695,652]	[418,954]	3	hSpCas9	negative selection	4485598
182866431	182866453	2	+	27760321	OCIAML2	viability	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.07498884171835651	[626,582]	[456,592]	1	hSpCas9	negative selection	4485599
182866077	182866099	2	+	27760321	MV411	viability	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.5138362132726608	[776,634]	[794,461]	3	hSpCas9	negative selection	4569058
182866114	182866136	2	+	27760321	MV411	viability	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.1113759755460324	[809,613]	[371,700]	0	hSpCas9	negative selection	4569059
182866163	182866185	2	-	27760321	MV411	viability	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	-0.20325118066879688	[249,238]	[73,239]	-1	hSpCas9	negative selection	4569060
182866329	182866351	2	+	27760321	MV411	viability	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	1.1436530801748197	[695,652]	[1304,501]	8	hSpCas9	negative selection	4569061
182866431	182866453	2	+	27760321	MV411	viability	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.751285899250514	[626,582]	[718,601]	5	hSpCas9	negative selection	4569062
182866077	182866099	2	+	27760321	HL60	viability	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.3425721194903813	[776,634]	[354,555]	-4	hSpCas9	negative selection	4652521
182866114	182866136	2	+	27760321	HL60	viability	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.5671397897178715	[809,613]	[632,1089]	6	hSpCas9	negative selection	4652522
182866163	182866185	2	-	27760321	HL60	viability	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.7655251015360024	[249,238]	[290,391]	8	hSpCas9	negative selection	4652523
182866329	182866351	2	+	27760321	HL60	viability	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.7942084405096426	[695,652]	[1108,793]	8	hSpCas9	negative selection	4652524
182866431	182866453	2	+	27760321	HL60	viability	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.17341912953861727	[626,582]	[540,574]	2	hSpCas9	negative selection	4652525
182866077	182866099	2	+	27760321	HT1080	viability	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.8834464883969899	[634,495]	[438,389]	5	hSpCas9	negative selection	4735984
182866114	182866136	2	+	27760321	HT1080	viability	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.04729057376212664	[613,478]	[65,398]	0	hSpCas9	negative selection	4735985
182866163	182866185	2	-	27760321	HT1080	viability	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	-1.8879327434198814	[238,186]	[31,12]	-6	hSpCas9	negative selection	4735986
182866329	182866351	2	+	27760321	HT1080	viability	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.7655839014962934	[652,509]	[537,235]	4	hSpCas9	negative selection	4735987
182866431	182866453	2	+	27760321	HT1080	viability	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.37832589980998066	[582,454]	[294,239]	2	hSpCas9	negative selection	4735988
182866077	182866099	2	+	27760321	HT29	viability after 7 days	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.2974803502470782	[634,495]	[1075,813,817]	4	hSpCas9	negative selection	4819447
182866114	182866136	2	+	27760321	HT29	viability after 7 days	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.29933061706848074	[613,478]	[1024,709,879]	4	hSpCas9	negative selection	4819448
182866163	182866185	2	-	27760321	HT29	viability after 7 days	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	-0.1248483093956757	[238,186]	[229,389,133]	-2	hSpCas9	negative selection	4819449
182866329	182866351	2	+	27760321	HT29	viability after 7 days	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.22472270201520272	[652,509]	[1161,849,655]	3	hSpCas9	negative selection	4819450
182866431	182866453	2	+	27760321	HT29	viability after 7 days	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.09235368664165233	[582,454]	[721,679,731]	1	hSpCas9	negative selection	4819451
182866077	182866099	2	+	27760321	HT29	viability after 25 days	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.30357740226286656	[634,495]	[773,530,1121]	3	hSpCas9	negative selection	4902910
182866114	182866136	2	+	27760321	HT29	viability after 25 days	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.38646576805245814	[613,478]	[1104,531,789]	4	hSpCas9	negative selection	4902911
182866163	182866185	2	-	27760321	HT29	viability after 25 days	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.5000889623877028	[238,186]	[421,334,261]	5	hSpCas9	negative selection	4902912
182866329	182866351	2	+	27760321	HT29	viability after 25 days	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.08398034890403583	[652,509]	[756,697,647]	0	hSpCas9	negative selection	4902913
182866431	182866453	2	+	27760321	HT29	viability after 25 days	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.20705094690553083	[582,454]	[619,605,847]	2	hSpCas9	negative selection	4902914
182866077	182866099	2	+	27760321	HT29	viability after 22 days	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.05480377898718858	[634,495]	[524,775,740]	0	hSpCas9	negative selection	4986373
182866114	182866136	2	+	27760321	HT29	viability after 22 days	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.4539914119344294	[613,478]	[913,801,878]	5	hSpCas9	negative selection	4986374
182866163	182866185	2	-	27760321	HT29	viability after 22 days	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.5584128588629231	[238,186]	[259,446,383]	6	hSpCas9	negative selection	4986375
182866329	182866351	2	+	27760321	HT29	viability after 22 days	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.3466023828259118	[652,509]	[840,852,870]	3	hSpCas9	negative selection	4986376
182866431	182866453	2	+	27760321	HT29	viability after 22 days	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.14802930663728675	[582,454]	[694,593,704]	1	hSpCas9	negative selection	4986377
182866077	182866099	2	+	27760321	HT29	viability after 19 days	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.394696088167348	[634,495]	[699,887,942]	4	hSpCas9	negative selection	5069836
182866114	182866136	2	+	27760321	HT29	viability after 19 days	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.33565867032916996	[613,478]	[704,678,965]	3	hSpCas9	negative selection	5069837
182866163	182866185	2	-	27760321	HT29	viability after 19 days	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.6897231210666597	[238,186]	[437,555,196]	7	hSpCas9	negative selection	5069838
182866329	182866351	2	+	27760321	HT29	viability after 19 days	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.37053011390535107	[652,509]	[1032,756,808]	3	hSpCas9	negative selection	5069839
182866431	182866453	2	+	27760321	HT29	viability after 19 days	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.3605183116427664	[582,454]	[837,836,623]	3	hSpCas9	negative selection	5069840
182866077	182866099	2	+	27760321	HT29	viability after 16 days	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.06748890853672151	[634,495]	[700,491,803]	0	hSpCas9	negative selection	5153299
182866114	182866136	2	+	27760321	HT29	viability after 16 days	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.3447964693532273	[613,478]	[820,565,951]	4	hSpCas9	negative selection	5153300
182866163	182866185	2	-	27760321	HT29	viability after 16 days	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.20557204441074706	[238,186]	[258,350,210]	2	hSpCas9	negative selection	5153301
182866329	182866351	2	+	27760321	HT29	viability after 16 days	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.3525790829893666	[652,509]	[1201,873,449]	4	hSpCas9	negative selection	5153302
182866431	182866453	2	+	27760321	HT29	viability after 16 days	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.09883617287023327	[582,454]	[587,552,722]	1	hSpCas9	negative selection	5153303
182866077	182866099	2	+	27760321	HT29	viability after 13 days	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.07456345750446203	[634,495]	[627,703,541]	-1	hSpCas9	negative selection	5236762
182866114	182866136	2	+	27760321	HT29	viability after 13 days	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.5698390306789886	[613,478]	[984,966,874]	7	hSpCas9	negative selection	5236763
182866163	182866185	2	-	27760321	HT29	viability after 13 days	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.1519901028771884	[238,186]	[261,273,286]	1	hSpCas9	negative selection	5236764
182866329	182866351	2	+	27760321	HT29	viability after 13 days	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.17101461654087935	[652,509]	[880,736,665]	2	hSpCas9	negative selection	5236765
182866431	182866453	2	+	27760321	HT29	viability after 13 days	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.1060266208517594	[582,454]	[762,606,577]	1	hSpCas9	negative selection	5236766
182866077	182866099	2	+	27760321	HT29	viability after 10 days	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.06872226524283087	[634,495]	[669,761,788]	0	hSpCas9	negative selection	5320225
182866114	182866136	2	+	27760321	HT29	viability after 10 days	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	0.19463536916392044	[613,478]	[749,704,882]	2	hSpCas9	negative selection	5320226
182866163	182866185	2	-	27760321	HT29	viability after 10 days	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	0.258490072042753	[238,186]	[317,448,193]	3	hSpCas9	negative selection	5320227
182866329	182866351	2	+	27760321	HT29	viability after 10 days	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.14745373257578753	[652,509]	[830,862,721]	2	hSpCas9	negative selection	5320228
182866431	182866453	2	+	27760321	HT29	viability after 10 days	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	0.42957868295863233	[582,454]	[1148,766,702]	6	hSpCas9	negative selection	5320229
182866077	182866099	2	+	27760321	MOLM13	viability	GCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.9896316620609467	[776,634]	[564,975]	7	hSpCas9	negative selection	5403688
182866114	182866136	2	+	27760321	MOLM13	viability	ACACGCCCCTGTCGTACACTGG	FRZB	ENSG00000162998	-0.4961179199177458	[809,613]	[308,259]	-3	hSpCas9	negative selection	5403689
182866163	182866185	2	-	27760321	MOLM13	viability	CATCAAGTACCGCCACTCGTGG	FRZB	ENSG00000162998	1.3495438951658265	[249,238]	[707,48]	8	hSpCas9	negative selection	5403690
182866329	182866351	2	+	27760321	MOLM13	viability	AGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.8309785613078191	[695,652]	[718,641]	6	hSpCas9	negative selection	5403691
182866431	182866453	2	+	27760321	MOLM13	viability	GGGATGCGGACGGGCTCACAGG	FRZB	ENSG00000162998	1.7797490042126285	[626,582]	[1610,798]	9	hSpCas9	negative selection	5403692
182867100	182867123	2	+	27661255	K562	viability	GCTGCGGCTGCGACCCTGGCTGG	FRZB	ENSG00000162998	-0.1782516653954307	[286,267]	[227,168]	-5	dCas9-KRAB	negative selection	5480906
182867117	182867140	2	+	27661255	K562	viability	GGCTGGCAGGAGGGACGCTCAGG	FRZB	ENSG00000162998	-0.18673338649395	[275,388]	[286,184]	-5	dCas9-KRAB	negative selection	5480907
182866076	182866099	2	+	27260156	BXPC3	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.00412375684037336	[867]	[881,796,1129,804]	0	hSpCas9	negative selection	5544207
182866328	182866351	2	+	27260156	BXPC3	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.0827012424260618	[1347]	[1459,1414,1402,1715]	1	hSpCas9	negative selection	5544208
182838481	182838504	2	-	27260156	BXPC3	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.2306501342059485	[238]	[291,261,328,289]	5	hSpCas9	negative selection	5544209
182838493	182838516	2	+	27260156	BXPC3	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.32109476754904587	[426]	[342,380,360,339]	-6	hSpCas9	negative selection	5608469
182858806	182858829	2	+	27260156	BXPC3	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.1480609604673514	[683]	[642,767,680,1129]	3	hSpCas9	negative selection	5608470
182858797	182858820	2	-	27260156	BXPC3	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	0.277443061579949	[250]	[370,276,319,295]	6	hSpCas9	negative selection	5608471
182866076	182866099	2	+	27260156	A673	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.08433648293229368	[867]	[1091,1155,1021,1147]	2	hSpCas9	negative selection	5665458
182866328	182866351	2	+	27260156	A673	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.00028714659632145256	[1347]	[1799,1350,1718,1629]	0	hSpCas9	negative selection	5665459
182838481	182838504	2	-	27260156	A673	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.19947266843001366	[238]	[361,284,304,372]	5	hSpCas9	negative selection	5665460
182838493	182838516	2	+	27260156	A673	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.31982414532706493	[426]	[441,343,380,484]	-7	hSpCas9	negative selection	5729720
182858806	182858829	2	+	27260156	A673	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.20426110366061745	[683]	[997,1019,956,803]	5	hSpCas9	negative selection	5729721
182858797	182858820	2	-	27260156	A673	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.002795214585212369	[250]	[200,292,284,418]	0	hSpCas9	negative selection	5729722
182866076	182866099	2	+	27260156	A375	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.16363384837221118	[867]	[1078,1422,1092,998]	2	hSpCas9	negative selection	5786709
182866328	182866351	2	+	27260156	A375	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.10646231258557082	[1347]	[1741,1826,1544,1679]	1	hSpCas9	negative selection	5786710
182838481	182838504	2	-	27260156	A375	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.27125974747277326	[238]	[286,382,397,289]	4	hSpCas9	negative selection	5786711
182838493	182838516	2	+	27260156	A375	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.4798851716247249	[426]	[480,247,450,247]	-6	hSpCas9	negative selection	5850971
182858806	182858829	2	+	27260156	A375	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.05674983536602862	[683]	[868,849,589,771]	-1	hSpCas9	negative selection	5850972
182858797	182858820	2	-	27260156	A375	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.4298031032147054	[250]	[202,181,209,263]	-5	hSpCas9	negative selection	5850973
182866076	182866099	2	+	27260156	COLO741	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.033002358482441596	[867]	[961,1410,881]	0	hSpCas9	negative selection	5907960
182866328	182866351	2	+	27260156	COLO741	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.14694479749499756	[1347]	[1603,1713,1363]	-3	hSpCas9	negative selection	5907961
182838481	182838504	2	-	27260156	COLO741	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.11396942512365171	[238]	[438,234,325]	2	hSpCas9	negative selection	5907962
182838493	182838516	2	+	27260156	COLO741	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.17352324656139123	[426]	[612,379,468]	-4	hSpCas9	negative selection	5972222
182858806	182858829	2	+	27260156	COLO741	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.0973623242763555	[683]	[1021,866,921]	2	hSpCas9	negative selection	5972223
182858797	182858820	2	-	27260156	COLO741	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.03939114177746639	[250]	[341,339,259]	-1	hSpCas9	negative selection	5972224
182866076	182866099	2	+	27260156	CAL120	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.024096030216453124	[867]	[1017,1064,1095]	0	hSpCas9	negative selection	6029211
182866328	182866351	2	+	27260156	CAL120	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.11357429101786098	[1347]	[1978,1399,1339]	-2	hSpCas9	negative selection	6029212
182838481	182838504	2	-	27260156	CAL120	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.09845512922613497	[238]	[270,359,316]	1	hSpCas9	negative selection	6029213
182838493	182838516	2	+	27260156	CAL120	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.6259763764534283	[426]	[352,331,348]	-7	hSpCas9	negative selection	6093473
182858806	182858829	2	+	27260156	CAL120	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.24885814786246985	[683]	[857,1268,885]	4	hSpCas9	negative selection	6093474
182858797	182858820	2	-	27260156	CAL120	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.3220486838252914	[250]	[94,204,422]	-5	hSpCas9	negative selection	6093475
182866076	182866099	2	+	27260156	CADOES1	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.2515791506435596	[867]	[843,565,617,683]	-4	hSpCas9	negative selection	6150462
182866328	182866351	2	+	27260156	CADOES1	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.07065837293295574	[1347]	[1358,1167,1451,1285]	1	hSpCas9	negative selection	6150463
182838481	182838504	2	-	27260156	CADOES1	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.35475417467474757	[238]	[204,283,393,252]	6	hSpCas9	negative selection	6150464
182838493	182838516	2	+	27260156	CADOES1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.4172412369288161	[426]	[316,295,139,441]	-6	hSpCas9	negative selection	6214724
182858806	182858829	2	+	27260156	CADOES1	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.3943689850071379	[683]	[935,936,675,793]	6	hSpCas9	negative selection	6214725
182858797	182858820	2	-	27260156	CADOES1	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.4032643677627372	[250]	[189,173,89,254]	-6	hSpCas9	negative selection	6214726
182866076	182866099	2	+	27260156	EWS502	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.014205245017936852	[867]	[1001,801,831,1079]	0	hSpCas9	negative selection	6271713
182866328	182866351	2	+	27260156	EWS502	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.009747877542943595	[1347]	[1238,1327,1297,1941]	0	hSpCas9	negative selection	6271714
182838481	182838504	2	-	27260156	EWS502	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.24174111239397267	[238]	[232,242,373,361]	4	hSpCas9	negative selection	6271715
182838493	182838516	2	+	27260156	EWS502	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.23593028658044435	[426]	[309,377,426,432]	-4	hSpCas9	negative selection	6335975
182858806	182858829	2	+	27260156	EWS502	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.055765227507309056	[683]	[640,723,877,784]	1	hSpCas9	negative selection	6335976
182858797	182858820	2	-	27260156	EWS502	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.10350250429395791	[250]	[204,253,211,327]	-2	hSpCas9	negative selection	6335977
182866076	182866099	2	+	27260156	EW8	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.037691171265225476	[867]	[758,724,627,793]	0	hSpCas9	negative selection	6392964
182866328	182866351	2	+	27260156	EW8	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.07419320182863465	[1347]	[1431,1105,846,1293]	1	hSpCas9	negative selection	6392965
182838481	182838504	2	-	27260156	EW8	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.41900039957535207	[238]	[299,251,232,258]	7	hSpCas9	negative selection	6392966
182838493	182838516	2	+	27260156	EW8	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.36428397304656845	[426]	[176,294,222,376]	-6	hSpCas9	negative selection	6457226
182858806	182858829	2	+	27260156	EW8	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.15912891341843638	[683]	[867,403,519,724]	3	hSpCas9	negative selection	6457227
182858797	182858820	2	-	27260156	EW8	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.07677778114954781	[250]	[187,211,165,208]	-1	hSpCas9	negative selection	6457228
182866076	182866099	2	+	27260156	CORL105	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.09054127757811892	[867]	[1042,817,1125,862]	-2	hSpCas9	negative selection	6514215
182866328	182866351	2	+	27260156	CORL105	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.223991379182239	[1347]	[1763,1765,2142,1744]	4	hSpCas9	negative selection	6514216
182838481	182838504	2	-	27260156	CORL105	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.28531486499185843	[238]	[409,273,337,344]	5	hSpCas9	negative selection	6514217
182838493	182838516	2	+	27260156	CORL105	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.433047960693965	[426]	[398,375,426,288]	-7	hSpCas9	negative selection	6578477
182858806	182858829	2	+	27260156	CORL105	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.06505021971261726	[683]	[843,709,1064,769]	1	hSpCas9	negative selection	6578478
182858797	182858820	2	-	27260156	CORL105	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.5364677961812816	[250]	[184,155,237,236]	-7	hSpCas9	negative selection	6578479
182866076	182866099	2	+	27260156	HS294T	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.4995660503820497	[867]	[195,262,229,267]	-6	hSpCas9	negative selection	6635466
182866328	182866351	2	+	27260156	HS294T	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.03152649096147475	[1347]	[490,557,531,554]	0	hSpCas9	negative selection	6635467
182838481	182838504	2	-	27260156	HS294T	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.31818126224048426	[238]	[72,130,119,144]	4	hSpCas9	negative selection	6635468
182838493	182838516	2	+	27260156	HS294T	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.6450768627454871	[426]	[79,129,95,119]	-7	hSpCas9	negative selection	6699728
182858806	182858829	2	+	27260156	HS294T	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.11886409740555792	[683]	[206,229,288,252]	-2	hSpCas9	negative selection	6699729
182858797	182858820	2	-	27260156	HS294T	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	0.23055000783520108	[250]	[70,184,80,120]	3	hSpCas9	negative selection	6699730
182866076	182866099	2	+	27260156	HCC44	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.42729267909156676	[867]	[511,797,1046,586]	-6	hSpCas9	negative selection	6756717
182866328	182866351	2	+	27260156	HCC44	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.0584802511756366	[1347]	[1899,1022,1525,1506]	-1	hSpCas9	negative selection	6756718
182838481	182838504	2	-	27260156	HCC44	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.025216093301966946	[238]	[278,245,311,271]	0	hSpCas9	negative selection	6756719
182838493	182838516	2	+	27260156	HCC44	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.4836123397433377	[426]	[335,250,577,268]	-6	hSpCas9	negative selection	6820979
182858806	182858829	2	+	27260156	HCC44	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.2771595508330701	[683]	[894,923,1410,602]	4	hSpCas9	negative selection	6820980
182858797	182858820	2	-	27260156	HCC44	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.5891851153037844	[250]	[152,115,375,148]	-7	hSpCas9	negative selection	6820981
182866076	182866099	2	+	27260156	G402	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.6059757274020223	[867]	[843,550,431,953]	-6	hSpCas9	negative selection	6877968
182866328	182866351	2	+	27260156	G402	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.13739746506924666	[1347]	[1840,1137,1933,1110]	-2	hSpCas9	negative selection	6877969
182838481	182838504	2	-	27260156	G402	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	-0.5347948216380052	[238]	[366,101,224,131]	-6	hSpCas9	negative selection	6877970
182838493	182838516	2	+	27260156	G402	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-1.0424655802536802	[426]	[354,258,329,89]	-8	hSpCas9	negative selection	6942230
182858806	182858829	2	+	27260156	G402	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.07952006321010108	[683]	[865,653,754,879]	-1	hSpCas9	negative selection	6942231
182858797	182858820	2	-	27260156	G402	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.5698618465331908	[250]	[304,335,140,70]	-6	hSpCas9	negative selection	6942232
182866076	182866099	2	+	27260156	L33	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.25877826776163293	[867]	[641,324,448,753]	-5	hSpCas9	negative selection	6999219
182866328	182866351	2	+	27260156	L33	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.10791274050516142	[1347]	[1562,566,845,1513]	2	hSpCas9	negative selection	6999220
182838481	182838504	2	-	27260156	L33	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.2790355407942394	[238]	[333,116,183,246]	6	hSpCas9	negative selection	6999221
182838493	182838516	2	+	27260156	L33	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.46207240615534706	[426]	[324,143,170,290]	-8	hSpCas9	negative selection	7063481
182858806	182858829	2	+	27260156	L33	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.011267026072619202	[683]	[782,278,367,704]	0	hSpCas9	negative selection	7063482
182858797	182858820	2	-	27260156	L33	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	0.028982764501241487	[250]	[253,122,152,226]	0	hSpCas9	negative selection	7063483
182866076	182866099	2	+	27260156	K562	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.05509605647511484	[867]	[1116,1053,671,436]	0	hSpCas9	negative selection	7120470
182866328	182866351	2	+	27260156	K562	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.19826232024777224	[1347]	[1338,1637,1416,1129]	2	hSpCas9	negative selection	7120471
182838481	182838504	2	-	27260156	K562	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	-0.03059879133854726	[238]	[342,209,118,172]	0	hSpCas9	negative selection	7120472
182838493	182838516	2	+	27260156	K562	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.2879536742621736	[426]	[314,257,497,181]	-4	hSpCas9	negative selection	7184732
182858806	182858829	2	+	27260156	K562	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.2626852119629014	[683]	[831,986,583,549]	3	hSpCas9	negative selection	7184733
182858797	182858820	2	-	27260156	K562	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	0.12476650736402384	[250]	[181,121,184,445]	1	hSpCas9	negative selection	7184734
182866076	182866099	2	+	27260156	HT29	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.1297455122611718	[867]	[1255,1206,1141,1031]	2	hSpCas9	negative selection	7241721
182866328	182866351	2	+	27260156	HT29	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.015817355106967135	[1347]	[1716,2057,1537,1375]	0	hSpCas9	negative selection	7241722
182838481	182838504	2	-	27260156	HT29	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.3383641494837961	[238]	[547,333,401,212]	6	hSpCas9	negative selection	7241723
182838493	182838516	2	+	27260156	HT29	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.0009545490097949971	[426]	[471,552,509,535]	0	hSpCas9	negative selection	7305983
182858806	182858829	2	+	27260156	HT29	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.31168143742070575	[683]	[1283,1168,885,836]	6	hSpCas9	negative selection	7305984
182858797	182858820	2	-	27260156	HT29	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	0.07006920559612961	[250]	[351,244,331,342]	1	hSpCas9	negative selection	7305985
182866076	182866099	2	+	27260156	MHHES1	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.23608873071255143	[867]	[794,1125,837,617]	-4	hSpCas9	negative selection	7362972
182866328	182866351	2	+	27260156	MHHES1	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.023459348133787694	[1347]	[1545,1714,1642,1147]	0	hSpCas9	negative selection	7362973
182838481	182838504	2	-	27260156	MHHES1	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.11009390683053977	[238]	[246,448,262,222]	2	hSpCas9	negative selection	7362974
182838493	182838516	2	+	27260156	MHHES1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.4780876525760063	[426]	[351,336,414,283]	-7	hSpCas9	negative selection	7427234
182858806	182858829	2	+	27260156	MHHES1	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.013984036558346347	[683]	[932,709,817,621]	0	hSpCas9	negative selection	7427235
182858797	182858820	2	-	27260156	MHHES1	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.07136837917480832	[250]	[257,287,308,225]	-1	hSpCas9	negative selection	7427236
182866076	182866099	2	+	27260156	MEWO	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.27640765765127717	[867]	[1291,820,897]	6	hSpCas9	negative selection	7484223
182866328	182866351	2	+	27260156	MEWO	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.11216437426065906	[1347]	[1269,1195,1053]	-2	hSpCas9	negative selection	7484224
182838481	182838504	2	-	27260156	MEWO	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.07288774347251792	[238]	[169,209,312]	1	hSpCas9	negative selection	7484225
182838493	182838516	2	+	27260156	MEWO	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.027363639394639122	[426]	[529,307,364]	0	hSpCas9	negative selection	7548485
182858806	182858829	2	+	27260156	MEWO	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.13936435059103036	[683]	[937,600,620]	3	hSpCas9	negative selection	7548486
182858797	182858820	2	-	27260156	MEWO	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.5581017461712452	[250]	[111,208,147]	-8	hSpCas9	negative selection	7548487
182866076	182866099	2	+	27260156	LNCAPCLONEFGC	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.16507397546951796	[867]	[947,1003,979,598]	2	hSpCas9	negative selection	7605474
182866328	182866351	2	+	27260156	LNCAPCLONEFGC	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.29753672623456673	[1347]	[1476,1505,1458,1553]	5	hSpCas9	negative selection	7605475
182838481	182838504	2	-	27260156	LNCAPCLONEFGC	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.2520975698629314	[238]	[158,257,263,352]	4	hSpCas9	negative selection	7605476
182838493	182838516	2	+	27260156	LNCAPCLONEFGC	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.052913132397697626	[426]	[198,449,328,504]	-1	hSpCas9	negative selection	7669736
182858806	182858829	2	+	27260156	LNCAPCLONEFGC	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.2763299713052142	[683]	[692,833,812,665]	4	hSpCas9	negative selection	7669737
182858797	182858820	2	-	27260156	LNCAPCLONEFGC	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.25019249529557563	[250]	[110,257,226,170]	-4	hSpCas9	negative selection	7669738
182866076	182866099	2	+	27260156	PANC0327	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.12547181754666903	[867]	[682,784,668,677]	-2	hSpCas9	negative selection	7726725
182866328	182866351	2	+	27260156	PANC0327	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.14581789716791582	[1347]	[938,931,1323,1141]	-2	hSpCas9	negative selection	7726726
182838481	182838504	2	-	27260156	PANC0327	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.6758716159575257	[238]	[374,226,364,406]	8	hSpCas9	negative selection	7726727
182838493	182838516	2	+	27260156	PANC0327	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.2391872395168309	[426]	[159,220,369,533]	-4	hSpCas9	negative selection	7790987
182858806	182858829	2	+	27260156	PANC0327	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.031365444669717135	[683]	[776,435,506,799]	0	hSpCas9	negative selection	7790988
182858797	182858820	2	-	27260156	PANC0327	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.7493627211433	[250]	[83,152,188,97]	-8	hSpCas9	negative selection	7790989
182866076	182866099	2	+	27260156	NCIH2009	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.33393412551559387	[867]	[1393,915,660]	-4	hSpCas9	negative selection	7847976
182866328	182866351	2	+	27260156	NCIH2009	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.27088713548227017	[1347]	[2735,2046,2125]	4	hSpCas9	negative selection	7847977
182838481	182838504	2	-	27260156	NCIH2009	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.15808722156496313	[238]	[354,353,404]	2	hSpCas9	negative selection	7847978
182838493	182838516	2	+	27260156	NCIH2009	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.619769621556119	[426]	[314,475,356]	-7	hSpCas9	negative selection	7912238
182858806	182858829	2	+	27260156	NCIH2009	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.050502741957814234	[683]	[1143,729,939]	0	hSpCas9	negative selection	7912239
182858797	182858820	2	-	27260156	NCIH2009	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.8524976327059008	[250]	[199,164,218]	-7	hSpCas9	negative selection	7912240
182866076	182866099	2	+	27260156	NCIH1373	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-1.271527730218354	[867]	[490,533,244,88]	-8	hSpCas9	negative selection	7969227
182866328	182866351	2	+	27260156	NCIH1373	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.3015256729318909	[1347]	[2050,990,1013,258]	-3	hSpCas9	negative selection	7969228
182838481	182838504	2	-	27260156	NCIH1373	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.5768267518260916	[238]	[391,419,132,175]	5	hSpCas9	negative selection	7969229
182838493	182838516	2	+	27260156	NCIH1373	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-1.3630019990936524	[426]	[235,168,147,52]	-8	hSpCas9	negative selection	8033489
182858806	182858829	2	+	27260156	NCIH1373	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.25897011653136925	[683]	[541,846,446,181]	-3	hSpCas9	negative selection	8033490
182858797	182858820	2	-	27260156	NCIH1373	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-1.4860297787409207	[250]	[135,109,78,20]	-9	hSpCas9	negative selection	8033491
182866076	182866099	2	+	27260156	PATU8902	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.13434241789654766	[867]	[1339,1990,1039,957]	1	hSpCas9	negative selection	8090478
182866328	182866351	2	+	27260156	PATU8902	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.26660374731433434	[1347]	[1504,1935,1369,1457]	-3	hSpCas9	negative selection	8090479
182838481	182838504	2	-	27260156	PATU8902	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.13335170793033058	[238]	[390,519,333,200]	1	hSpCas9	negative selection	8090480
182838493	182838516	2	+	27260156	PATU8902	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.7462751713842486	[426]	[308,501,282,338]	-6	hSpCas9	negative selection	8154740
182858806	182858829	2	+	27260156	PATU8902	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.6398385894415817	[683]	[1726,1471,1014,1876]	6	hSpCas9	negative selection	8154741
182858797	182858820	2	-	27260156	PATU8902	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.24991870651683046	[250]	[114,420,215,464]	-3	hSpCas9	negative selection	8154742
182866076	182866099	2	+	27260156	PANC1	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.06782169951279016	[867]	[679,924,655,629]	-1	hSpCas9	negative selection	8211729
182866328	182866351	2	+	27260156	PANC1	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.08158720192236935	[1347]	[957,1471,1188,859]	-1	hSpCas9	negative selection	8211730
182838481	182838504	2	-	27260156	PANC1	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.022498924109897067	[238]	[170,421,124,163]	0	hSpCas9	negative selection	8211731
182838493	182838516	2	+	27260156	PANC1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.2526012278070605	[426]	[292,371,250,320]	-4	hSpCas9	negative selection	8275991
182858806	182858829	2	+	27260156	PANC1	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.1766030125395131	[683]	[582,555,643,326]	-3	hSpCas9	negative selection	8275992
182858797	182858820	2	-	27260156	PANC1	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.7639126850622004	[250]	[194,149,87,82]	-8	hSpCas9	negative selection	8275993
182866076	182866099	2	+	27260156	PANC0813	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.04692192411953677	[867]	[1044,1212,583,1100]	0	hSpCas9	negative selection	8332980
182866328	182866351	2	+	27260156	PANC0813	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.2701352444329779	[1347]	[2191,2003,1809,1667]	4	hSpCas9	negative selection	8332981
182838481	182838504	2	-	27260156	PANC0813	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.29517089498285687	[238]	[522,359,251,262]	5	hSpCas9	negative selection	8332982
182838493	182838516	2	+	27260156	PANC0813	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.4433582655731536	[426]	[460,331,369,322]	-6	hSpCas9	negative selection	8397242
182858806	182858829	2	+	27260156	PANC0813	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.29253971391805494	[683]	[841,561,703,538]	-4	hSpCas9	negative selection	8397243
182858797	182858820	2	-	27260156	PANC0813	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.09684618005025869	[250]	[441,295,225,159]	-1	hSpCas9	negative selection	8397244
182866076	182866099	2	+	27260156	RDES	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.15336180948731415	[867]	[729,846,1233,788]	-3	hSpCas9	negative selection	8454231
182866328	182866351	2	+	27260156	RDES	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.1436914474129869	[1347]	[1093,1361,1532,1703]	-2	hSpCas9	negative selection	8454232
182838481	182838504	2	-	27260156	RDES	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	-0.002942314691142922	[238]	[198,218,350,357]	0	hSpCas9	negative selection	8454233
182838493	182838516	2	+	27260156	RDES	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.6886584195517893	[426]	[254,304,318,347]	-8	hSpCas9	negative selection	8518493
182858806	182858829	2	+	27260156	RDES	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.20296754522504	[683]	[734,980,848,1082]	3	hSpCas9	negative selection	8518494
182858797	182858820	2	-	27260156	RDES	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.5325619891055708	[250]	[142,224,209,228]	-7	hSpCas9	negative selection	8518495
182866076	182866099	2	+	27260156	PC3	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.09235416067952895	[867]	[555,904,1947,747]	2	hSpCas9	negative selection	8575482
182866328	182866351	2	+	27260156	PC3	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.0325613675451919	[1347]	[944,1049,2009,1564]	0	hSpCas9	negative selection	8575483
182838481	182838504	2	-	27260156	PC3	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	-0.06396878779312831	[238]	[201,150,364,232]	-1	hSpCas9	negative selection	8575484
182838493	182838516	2	+	27260156	PC3	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.21535929303764267	[426]	[290,282,665,335]	-5	hSpCas9	negative selection	8639744
182858806	182858829	2	+	27260156	PC3	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.12823941778354175	[683]	[481,747,1086,840]	3	hSpCas9	negative selection	8639745
182858797	182858820	2	-	27260156	PC3	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.2467610656590682	[250]	[108,246,377,198]	-5	hSpCas9	negative selection	8639746
182866076	182866099	2	+	27260156	PATU8988T	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.12737065246561652	[867]	[747,790,722,815]	-2	hSpCas9	negative selection	8696733
182866328	182866351	2	+	27260156	PATU8988T	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.06764621145840843	[1347]	[1045,1643,1374,1425]	1	hSpCas9	negative selection	8696734
182838481	182838504	2	-	27260156	PATU8988T	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.8868741312492568	[238]	[366,588,443,313]	9	hSpCas9	negative selection	8696735
182838493	182838516	2	+	27260156	PATU8988T	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.06207572097440833	[426]	[391,343,486,347]	-1	hSpCas9	negative selection	8760995
182858806	182858829	2	+	27260156	PATU8988T	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.5361242829206847	[683]	[1167,906,757,1001]	8	hSpCas9	negative selection	8760996
182858797	182858820	2	-	27260156	PATU8988T	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	0.38263026799215993	[250]	[401,368,130,374]	6	hSpCas9	negative selection	8760997
182866076	182866099	2	+	27260156	T47D	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.05845862898796028	[867]	[1146,899,1110,1066]	1	hSpCas9	negative selection	8817984
182866328	182866351	2	+	27260156	T47D	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.0655582328313642	[1347]	[1711,1556,1596,1717]	1	hSpCas9	negative selection	8817985
182838481	182838504	2	-	27260156	T47D	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	-0.052262736298334334	[238]	[236,271,257,307]	-1	hSpCas9	negative selection	8817986
182838493	182838516	2	+	27260156	T47D	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.3016329760359699	[426]	[462,346,352,458]	-6	hSpCas9	negative selection	8882246
182858806	182858829	2	+	27260156	T47D	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.27757473328686477	[683]	[952,899,960,1057]	6	hSpCas9	negative selection	8882247
182858797	182858820	2	-	27260156	T47D	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.07813238432331737	[250]	[244,244,291,329]	-2	hSpCas9	negative selection	8882248
182866076	182866099	2	+	27260156	SU8686	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.3117172226308407	[867]	[498,551,754,1064]	-5	hSpCas9	negative selection	8939235
182866328	182866351	2	+	27260156	SU8686	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.12386011615370962	[1347]	[1121,1281,1583,1974]	2	hSpCas9	negative selection	8939236
182838481	182838504	2	-	27260156	SU8686	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.3370418094875699	[238]	[248,225,428,311]	6	hSpCas9	negative selection	8939237
182838493	182838516	2	+	27260156	SU8686	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.6293928019807198	[426]	[202,317,298,275]	-7	hSpCas9	negative selection	9003497
182858806	182858829	2	+	27260156	SU8686	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	-0.01225932557060816	[683]	[666,656,850,486]	0	hSpCas9	negative selection	9003498
182858797	182858820	2	-	27260156	SU8686	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	0.04561440312089704	[250]	[168,114,410,383]	0	hSpCas9	negative selection	9003499
182866076	182866099	2	+	27260156	SKES1	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	0.08063429323290727	[867]	[837,1309,896,673]	1	hSpCas9	negative selection	9060486
182866328	182866351	2	+	27260156	SKES1	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.008919739842558005	[1347]	[1559,1775,1099,1077]	0	hSpCas9	negative selection	9060487
182838481	182838504	2	-	27260156	SKES1	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.03960481577247188	[238]	[424,183,198,193]	0	hSpCas9	negative selection	9060488
182838493	182838516	2	+	27260156	SKES1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.26444379481335456	[426]	[362,410,300,348]	-5	hSpCas9	negative selection	9124748
182858806	182858829	2	+	27260156	SKES1	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.2421828197484618	[683]	[804,1150,722,606]	5	hSpCas9	negative selection	9124749
182858797	182858820	2	-	27260156	SKES1	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.4349970075157188	[250]	[282,126,151,183]	-7	hSpCas9	negative selection	9124750
182866076	182866099	2	+	27260156	TOV112D	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.11412406182653523	[867]	[934,1009,613,716]	-2	hSpCas9	negative selection	9181737
182866328	182866351	2	+	27260156	TOV112D	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	-0.11565990299521522	[1347]	[1038,1557,1358,1089]	-2	hSpCas9	negative selection	9181738
182838481	182838504	2	-	27260156	TOV112D	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.14654240110515004	[238]	[183,206,152,487]	3	hSpCas9	negative selection	9181739
182838493	182838516	2	+	27260156	TOV112D	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.031182426410227643	[426]	[240,388,543,541]	0	hSpCas9	negative selection	9245999
182858806	182858829	2	+	27260156	TOV112D	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.33990946003067435	[683]	[648,1038,798,999]	6	hSpCas9	negative selection	9246000
182858797	182858820	2	-	27260156	TOV112D	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.01626494624979724	[250]	[151,269,319,248]	0	hSpCas9	negative selection	9246001
182866076	182866099	2	+	27260156	TC71	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.02006836109791832	[867]	[889,989,837,957]	0	hSpCas9	negative selection	9302988
182866328	182866351	2	+	27260156	TC71	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.012422387729406292	[1347]	[1200,1430,1560,1650]	0	hSpCas9	negative selection	9302989
182838481	182838504	2	-	27260156	TC71	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	0.18007507783770937	[238]	[215,365,256,326]	4	hSpCas9	negative selection	9302990
182838493	182838516	2	+	27260156	TC71	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.22827382088160564	[426]	[394,309,368,495]	-6	hSpCas9	negative selection	9367250
182858806	182858829	2	+	27260156	TC71	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.26504344443444217	[683]	[1013,868,921,703]	6	hSpCas9	negative selection	9367251
182858797	182858820	2	-	27260156	TC71	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.16194599104005425	[250]	[240,263,223,232]	-4	hSpCas9	negative selection	9367252
182866076	182866099	2	+	27260156	TC32	viability	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.051146010993250224	[867]	[786,571,1001,863]	-1	hSpCas9	negative selection	9424239
182866328	182866351	2	+	27260156	TC32	viability	CAGACCTTCGAACTGCTCGATGG	FRZB	ENSG00000162998	0.1291430335862953	[1347]	[1394,1029,1750,1483]	2	hSpCas9	negative selection	9424240
182838481	182838504	2	-	27260156	TC32	viability	GTCAACCTCTATACCAGCTCTGG	FRZB	ENSG00000162998	-0.13996476136159464	[238]	[217,138,239,236]	-2	hSpCas9	negative selection	9424241
182838493	182838516	2	+	27260156	TC32	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.7797949396020152	[426]	[159,250,223,288]	-9	hSpCas9	negative selection	9488501
182858806	182858829	2	+	27260156	TC32	viability	TTTCCGTTACTAGAATCCATAGG	FRZB	ENSG00000162998	0.023352991943032975	[683]	[654,608,830,514]	0	hSpCas9	negative selection	9488502
182858797	182858820	2	-	27260156	TC32	viability	TCTAGTAACGGAAACTGTAGAGG	FRZB	ENSG00000162998	-0.31685078336920136	[250]	[141,114,275,267]	-5	hSpCas9	negative selection	9488503
182838493	182838516	2	+	27869803	HPAFII	viability after 27 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.7269646653247277	[263]	[118,321,NaN]	6	hSpCas9	negative selection	9572599
182838510	182838533	2	+	27869803	HPAFII	viability after 27 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.6344260601655742	[439]	[471,264,NaN]	5	hSpCas9	negative selection	9572600
182866076	182866099	2	+	27869803	HPAFII	viability after 27 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-1.0211824458877519	[517]	[203,75,NaN]	-6	hSpCas9	negative selection	9572601
182866099	182866122	2	-	27869803	HPAFII	viability after 27 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-1.8093851397905025	[119]	[17,17,NaN]	-8	hSpCas9	negative selection	9572602
182866150	182866173	2	-	27869803	HPAFII	viability after 27 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.2956733426368531	[344]	[256,193,NaN]	2	hSpCas9	negative selection	9572603
182866396	182866419	2	+	27869803	HPAFII	viability after 27 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.5907958077064932	[192]	[250,70,NaN]	5	hSpCas9	negative selection	9572604
182838493	182838516	2	+	27869803	HPAFII	viability after 15 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.05320439101595421	[263]	[159,343,NaN]	0	hSpCas9	negative selection	9655048
182838510	182838533	2	+	27869803	HPAFII	viability after 15 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.30616123881125357	[439]	[863,410,NaN]	3	hSpCas9	negative selection	9655049
182866076	182866099	2	+	27869803	HPAFII	viability after 15 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-1.2526744394805338	[517]	[417,118,NaN]	-8	hSpCas9	negative selection	9655050
182866099	182866122	2	-	27869803	HPAFII	viability after 15 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.8213546065010258	[119]	[80,67,NaN]	-7	hSpCas9	negative selection	9655051
182866150	182866173	2	-	27869803	HPAFII	viability after 15 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.4615300373302955	[344]	[689,398,NaN]	5	hSpCas9	negative selection	9655052
182866396	182866419	2	+	27869803	HPAFII	viability after 15 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.7818202026060749	[192]	[585,213,NaN]	8	hSpCas9	negative selection	9655053
182838493	182838516	2	+	27869803	ASPC1	viability after 36 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.7645107626411426	[743]	[666,196,471]	7	hSpCas9	negative selection	9737497
182838510	182838533	2	+	27869803	ASPC1	viability after 36 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.4107635592171974	[1475]	[967,208,856]	4	hSpCas9	negative selection	9737498
182866076	182866099	2	+	27869803	ASPC1	viability after 36 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.2807030699804858	[1118]	[565,237,212]	-3	hSpCas9	negative selection	9737499
182866099	182866122	2	-	27869803	ASPC1	viability after 36 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-1.0076460573216073	[215]	[58,0,50]	-7	hSpCas9	negative selection	9737500
182866150	182866173	2	-	27869803	ASPC1	viability after 36 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.42217894735707023	[864]	[223,808,205]	4	hSpCas9	negative selection	9737501
182866396	182866419	2	+	27869803	ASPC1	viability after 36 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.08153203854254987	[776]	[200,202,410]	0	hSpCas9	negative selection	9737502
182838493	182838516	2	+	27869803	PATU8988S	viability after 35 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.31976965381875655	[550]	[267,285,NaN]	3	hSpCas9	negative selection	9819946
182838510	182838533	2	+	27869803	PATU8988S	viability after 35 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.4828148112132621	[1029]	[673,484,NaN]	5	hSpCas9	negative selection	9819947
182866076	182866099	2	+	27869803	PATU8988S	viability after 35 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	1.3905738603096482	[919]	[1175,765,NaN]	9	hSpCas9	negative selection	9819948
182866099	182866122	2	-	27869803	PATU8988S	viability after 35 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.12102617940393878	[323]	[115,123,NaN]	-1	hSpCas9	negative selection	9819949
182866150	182866173	2	-	27869803	PATU8988S	viability after 35 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	1.0773648376268643	[778]	[684,638,NaN]	9	hSpCas9	negative selection	9819950
182866396	182866419	2	+	27869803	PATU8988S	viability after 35 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.3020287598653481	[545]	[319,221,NaN]	3	hSpCas9	negative selection	9819951
182838493	182838516	2	+	27869803	PATU8988S	viability after 31 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.5250121922906072	[550]	[254,393,NaN]	6	hSpCas9	negative selection	9902395
182838510	182838533	2	+	27869803	PATU8988S	viability after 31 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.0709406519875353	[1029]	[459,394,NaN]	0	hSpCas9	negative selection	9902396
182866076	182866099	2	+	27869803	PATU8988S	viability after 31 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	1.0315145399860877	[919]	[803,680,NaN]	9	hSpCas9	negative selection	9902397
182866099	182866122	2	-	27869803	PATU8988S	viability after 31 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.07053967211046985	[323]	[70,217,NaN]	0	hSpCas9	negative selection	9902398
182866150	182866173	2	-	27869803	PATU8988S	viability after 31 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.9575171706713157	[778]	[483,754,NaN]	9	hSpCas9	negative selection	9902399
182866396	182866419	2	+	27869803	PATU8988S	viability after 31 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.2881313297705371	[545]	[271,257,NaN]	3	hSpCas9	negative selection	9902400
182838493	182838516	2	+	27869803	HPAFII	viability after 35 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	1.3379326346147589	[263]	[152,545,NaN]	8	hSpCas9	negative selection	9984844
182838510	182838533	2	+	27869803	HPAFII	viability after 35 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.687408875898216	[439]	[369,345,NaN]	4	hSpCas9	negative selection	9984845
182866076	182866099	2	+	27869803	HPAFII	viability after 35 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-1.249063740847099	[517]	[178,32,NaN]	-6	hSpCas9	negative selection	9984846
182866099	182866122	2	-	27869803	HPAFII	viability after 35 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-3.192691608069986	[119]	[0,12,NaN]	-8	hSpCas9	negative selection	9984847
182866150	182866173	2	-	27869803	HPAFII	viability after 35 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.6595818426212107	[344]	[289,259,NaN]	4	hSpCas9	negative selection	9984848
182866396	182866419	2	+	27869803	HPAFII	viability after 35 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	1.3658928025690293	[192]	[367,120,NaN]	8	hSpCas9	negative selection	9984849
182838493	182838516	2	+	27869803	HPAFII	viability after 31 days	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.8258963832737808	[263]	[153,380,NaN]	6	hSpCas9	negative selection	10067293
182838510	182838533	2	+	27869803	HPAFII	viability after 31 days	CCGTGGAATGTTTACCAGAGAGG	FRZB	ENSG00000162998	0.5902558574314327	[439]	[332,413,NaN]	4	hSpCas9	negative selection	10067294
182866076	182866099	2	+	27869803	HPAFII	viability after 31 days	AGCTCCGTCCGCAGTAACGATGG	FRZB	ENSG00000162998	-0.927531766393545	[517]	[260,34,NaN]	-5	hSpCas9	negative selection	10067295
182866099	182866122	2	-	27869803	HPAFII	viability after 31 days	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-1.3064700089682857	[119]	[9,45,NaN]	-7	hSpCas9	negative selection	10067296
182866150	182866173	2	-	27869803	HPAFII	viability after 31 days	CCACTCGTGGCCGGAGAACCTGG	FRZB	ENSG00000162998	0.732779040532303	[344]	[349,290,NaN]	5	hSpCas9	negative selection	10067297
182866396	182866419	2	+	27869803	HPAFII	viability after 31 days	TCTTAGTCATGTTCCAGGGCAGG	FRZB	ENSG00000162998	0.6098570768121289	[192]	[238,84,NaN]	4	hSpCas9	negative selection	10067298
182866478	182866501	2	+	28162770	P31FUJ	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.4144090109043261	[185]	[81]	-7	hSpCas9	negative selection	10159090
182866099	182866122	2	-	28162770	P31FUJ	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.8549563013601822	[286]	[609]	8	hSpCas9	negative selection	10159091
182866120	182866143	2	-	28162770	P31FUJ	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.6302621502295129	[126]	[230]	7	hSpCas9	negative selection	10159092
182866509	182866532	2	-	28162770	P31FUJ	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	1.0473057147783567	[13]	[33]	9	hSpCas9	negative selection	10159093
182866409	182866432	2	+	28162770	P31FUJ	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	1.120834750200322	[44]	[114]	9	hSpCas9	negative selection	10159094
182866153	182866176	2	+	28162770	P31FUJ	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	-0.4268892565306812	[142]	[124]	-4	hSpCas9	negative selection	10159095
182838493	182838516	2	+	28162770	P31FUJ	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.6942923656709322	[262]	[190]	-5	hSpCas9	negative selection	10159096
182866343	182866366	2	+	28162770	P31FUJ	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.14357367449535996	[311]	[404]	1	hSpCas9	negative selection	10159097
182866298	182866321	2	+	28162770	P31FUJ	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.5998596747914007	[137]	[106]	-5	hSpCas9	negative selection	10159098
182866288	182866311	2	+	28162770	P31FUJ	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.4376296384961268	[141]	[225]	5	hSpCas9	negative selection	10159099
182866478	182866501	2	+	28162770	TF1	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10328456
182866099	182866122	2	-	28162770	TF1	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10328457
182866120	182866143	2	-	28162770	TF1	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10328458
182866509	182866532	2	-	28162770	TF1	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10328459
182866409	182866432	2	+	28162770	TF1	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10328460
182866153	182866176	2	+	28162770	TF1	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10328461
182838493	182838516	2	+	28162770	TF1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10328462
182866343	182866366	2	+	28162770	TF1	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10328463
182866298	182866321	2	+	28162770	TF1	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10328464
182866288	182866311	2	+	28162770	TF1	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10328465
182866478	182866501	2	+	28162770	SKM1	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.3554338981030796	[54]	[37]	-7	hSpCas9	negative selection	10497822
182866099	182866122	2	-	28162770	SKM1	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.9784668384503586	[59]	[208]	8	hSpCas9	negative selection	10497823
182866120	182866143	2	-	28162770	SKM1	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.9269365378102767	[35]	[120]	8	hSpCas9	negative selection	10497824
182866509	182866532	2	-	28162770	SKM1	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	0.1779983019779947	[11]	[23]	1	hSpCas9	negative selection	10497825
182866409	182866432	2	+	28162770	SKM1	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	1.9853532240355984	[8]	[62]	9	hSpCas9	negative selection	10497826
182866153	182866176	2	+	28162770	SKM1	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.43365317744619086	[48]	[116]	4	hSpCas9	negative selection	10497827
182838493	182838516	2	+	28162770	SKM1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.12141477361162706	[38]	[74]	1	hSpCas9	negative selection	10497828
182866343	182866366	2	+	28162770	SKM1	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.8198631939336276	[57]	[180]	7	hSpCas9	negative selection	10497829
182866298	182866321	2	+	28162770	SKM1	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.321572707512517	[40]	[57]	-3	hSpCas9	negative selection	10497830
182866288	182866311	2	+	28162770	SKM1	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	-0.42968427524324504	[31]	[41]	-4	hSpCas9	negative selection	10497831
182866478	182866501	2	+	28162770	SKM1	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.3554338981030796	[54]	[37]	-7	hSpCas9	negative selection	10667188
182866099	182866122	2	-	28162770	SKM1	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.9784668384503586	[59]	[208]	8	hSpCas9	negative selection	10667189
182866120	182866143	2	-	28162770	SKM1	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.9269365378102767	[35]	[120]	8	hSpCas9	negative selection	10667190
182866509	182866532	2	-	28162770	SKM1	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	0.1779983019779947	[11]	[23]	1	hSpCas9	negative selection	10667191
182866409	182866432	2	+	28162770	SKM1	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	1.9853532240355984	[8]	[62]	9	hSpCas9	negative selection	10667192
182866153	182866176	2	+	28162770	SKM1	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.43365317744619086	[48]	[116]	4	hSpCas9	negative selection	10667193
182838493	182838516	2	+	28162770	SKM1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.12141477361162706	[38]	[74]	1	hSpCas9	negative selection	10667194
182866343	182866366	2	+	28162770	SKM1	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.8198631939336276	[57]	[180]	7	hSpCas9	negative selection	10667195
182866298	182866321	2	+	28162770	SKM1	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.321572707512517	[40]	[57]	-3	hSpCas9	negative selection	10667196
182866288	182866311	2	+	28162770	SKM1	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	-0.42968427524324504	[31]	[41]	-4	hSpCas9	negative selection	10667197
182866478	182866501	2	+	28162770	PL21	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	1.0535471168776316	[206]	[186]	8	hSpCas9	negative selection	10836554
182866099	182866122	2	-	28162770	PL21	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.2551060737072486	[205]	[106]	2	hSpCas9	negative selection	10836555
182866120	182866143	2	-	28162770	PL21	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.3238749829115649	[133]	[72]	3	hSpCas9	negative selection	10836556
182866509	182866532	2	-	28162770	PL21	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	0.6781869112939645	[55]	[38]	6	hSpCas9	negative selection	10836557
182866409	182866432	2	+	28162770	PL21	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	-0.5302533257533999	[72]	[21]	-4	hSpCas9	negative selection	10836558
182866153	182866176	2	+	28162770	PL21	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	1.3284637114648596	[171]	[187]	9	hSpCas9	negative selection	10836559
182838493	182838516	2	+	28162770	PL21	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	1.4931865893895535	[110]	[135]	9	hSpCas9	negative selection	10836560
182866343	182866366	2	+	28162770	PL21	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.751993803398538	[190]	[139]	6	hSpCas9	negative selection	10836561
182866298	182866321	2	+	28162770	PL21	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.7998603855106798	[95]	[23]	-5	hSpCas9	negative selection	10836562
182866288	182866311	2	+	28162770	PL21	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.7268875012651806	[117]	[84]	6	hSpCas9	negative selection	10836563
182866478	182866501	2	+	28162770	P31FUJ	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.4144090109043261	[185]	[81]	-7	hSpCas9	negative selection	11005920
182866099	182866122	2	-	28162770	P31FUJ	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.8549563013601822	[286]	[609]	8	hSpCas9	negative selection	11005921
182866120	182866143	2	-	28162770	P31FUJ	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.6302621502295129	[126]	[230]	7	hSpCas9	negative selection	11005922
182866509	182866532	2	-	28162770	P31FUJ	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	1.0473057147783567	[13]	[33]	9	hSpCas9	negative selection	11005923
182866409	182866432	2	+	28162770	P31FUJ	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	1.120834750200322	[44]	[114]	9	hSpCas9	negative selection	11005924
182866153	182866176	2	+	28162770	P31FUJ	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	-0.4268892565306812	[142]	[124]	-4	hSpCas9	negative selection	11005925
182838493	182838516	2	+	28162770	P31FUJ	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.6942923656709322	[262]	[190]	-5	hSpCas9	negative selection	11005926
182866343	182866366	2	+	28162770	P31FUJ	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.14357367449535996	[311]	[404]	1	hSpCas9	negative selection	11005927
182866298	182866321	2	+	28162770	P31FUJ	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.5998596747914007	[137]	[106]	-5	hSpCas9	negative selection	11005928
182866288	182866311	2	+	28162770	P31FUJ	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.4376296384961268	[141]	[225]	5	hSpCas9	negative selection	11005929
182866478	182866501	2	+	28162770	OCIAML5	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.6176013172269739	[84]	[49]	-7	hSpCas9	negative selection	11175286
182866099	182866122	2	-	28162770	OCIAML5	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.4080562395498934	[123]	[296]	3	hSpCas9	negative selection	11175287
182866120	182866143	2	-	28162770	OCIAML5	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	-0.49252418417685684	[105]	[135]	-3	hSpCas9	negative selection	11175288
182866509	182866532	2	-	28162770	OCIAML5	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	2.8108984418584315	[5]	[75]	9	hSpCas9	negative selection	11175289
182866409	182866432	2	+	28162770	OCIAML5	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	0.7694218058822733	[38]	[119]	6	hSpCas9	negative selection	11175290
182866153	182866176	2	+	28162770	OCIAML5	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.36180177816591225	[96]	[224]	3	hSpCas9	negative selection	11175291
182838493	182838516	2	+	28162770	OCIAML5	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.22593594113727622	[89]	[189]	2	hSpCas9	negative selection	11175292
182866343	182866366	2	+	28162770	OCIAML5	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.9205229330329303	[143]	[491]	7	hSpCas9	negative selection	11175293
182866298	182866321	2	+	28162770	OCIAML5	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-3.117411137384992	[124]	[25]	-9	hSpCas9	negative selection	11175294
182866288	182866311	2	+	28162770	OCIAML5	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	-0.2136648111813805	[105]	[164]	-1	hSpCas9	negative selection	11175295
182866478	182866501	2	+	28162770	EOL1	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.15021999683143758	[296]	[140]	-1	hSpCas9	negative selection	11344652
182866099	182866122	2	-	28162770	EOL1	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	-0.12990001245184174	[296]	[142]	-1	hSpCas9	negative selection	11344653
182866120	182866143	2	-	28162770	EOL1	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	-0.021922832012670347	[290]	[150]	0	hSpCas9	negative selection	11344654
182866509	182866532	2	-	28162770	EOL1	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	1.499241936837864	[46]	[69]	9	hSpCas9	negative selection	11344655
182866409	182866432	2	+	28162770	EOL1	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	0.3331874996512276	[112]	[74]	3	hSpCas9	negative selection	11344656
182866153	182866176	2	+	28162770	EOL1	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.9622400616424853	[339]	[348]	8	hSpCas9	negative selection	11344657
182838493	182838516	2	+	28162770	EOL1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.8530598070930177	[191]	[55]	-5	hSpCas9	negative selection	11344658
182866343	182866366	2	+	28162770	EOL1	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	-0.5007580631621364	[281]	[104]	-4	hSpCas9	negative selection	11344659
182866298	182866321	2	+	28162770	EOL1	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	0.6540958941742577	[116]	[96]	6	hSpCas9	negative selection	11344660
182866288	182866311	2	+	28162770	EOL1	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.30787641112204	[160]	[104]	3	hSpCas9	negative selection	11344661
182866478	182866501	2	+	28162770	MOLM13	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.3580812186803723	[272]	[76]	-6	hSpCas9	negative selection	11514018
182866099	182866122	2	-	28162770	MOLM13	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.507148811991806	[289]	[297]	4	hSpCas9	negative selection	11514019
182866120	182866143	2	-	28162770	MOLM13	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	1.5824713491431162	[247]	[536]	9	hSpCas9	negative selection	11514020
182866509	182866532	2	-	28162770	MOLM13	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	-1.184187315035114	[43]	[13]	-6	hSpCas9	negative selection	11514021
182866409	182866432	2	+	28162770	MOLM13	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	0.401291632815555	[132]	[126]	3	hSpCas9	negative selection	11514022
182866153	182866176	2	+	28162770	MOLM13	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	1.3922004499480323	[224]	[426]	9	hSpCas9	negative selection	11514023
182838493	182838516	2	+	28162770	MOLM13	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.0616599988579708	[165]	[114]	0	hSpCas9	negative selection	11514024
182866343	182866366	2	+	28162770	MOLM13	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.7836275403127433	[326]	[406]	6	hSpCas9	negative selection	11514025
182866298	182866321	2	+	28162770	MOLM13	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	0.10373305126791932	[129]	[100]	0	hSpCas9	negative selection	11514026
182866288	182866311	2	+	28162770	MOLM13	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.8135609363559186	[228]	[290]	6	hSpCas9	negative selection	11514027
182866478	182866501	2	+	28162770	HEL	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.512539393477554	[244]	[54]	-7	hSpCas9	negative selection	11683384
182866099	182866122	2	-	28162770	HEL	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.17111780435514568	[207]	[149]	1	hSpCas9	negative selection	11683385
182866120	182866143	2	-	28162770	HEL	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.16023836494277433	[196]	[140]	1	hSpCas9	negative selection	11683386
182866509	182866532	2	-	28162770	HEL	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	-0.9977187813125026	[52]	[16]	-6	hSpCas9	negative selection	11683387
182866409	182866432	2	+	28162770	HEL	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	0.8690146878240331	[105]	[123]	7	hSpCas9	negative selection	11683388
182866153	182866176	2	+	28162770	HEL	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	-0.008457367120885975	[233]	[148]	0	hSpCas9	negative selection	11683389
182838493	182838516	2	+	28162770	HEL	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	1.1562661946785642	[137]	[196]	8	hSpCas9	negative selection	11683390
182866343	182866366	2	+	28162770	HEL	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.7535846006886469	[287]	[310]	6	hSpCas9	negative selection	11683391
182866298	182866321	2	+	28162770	HEL	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	0.5596830922727983	[142]	[134]	5	hSpCas9	negative selection	11683392
182866288	182866311	2	+	28162770	HEL	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	-0.3220717395373429	[161]	[82]	-2	hSpCas9	negative selection	11683393
182866478	182866501	2	+	28162770	MV411	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-3.0471831981088515	[156]	[15]	-9	hSpCas9	negative selection	11852750
182866099	182866122	2	-	28162770	MV411	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.2865373704717159	[181]	[186]	2	hSpCas9	negative selection	11852751
182866120	182866143	2	-	28162770	MV411	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	1.3725649382364304	[148]	[324]	9	hSpCas9	negative selection	11852752
182866509	182866532	2	-	28162770	MV411	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	1.9732625873437812	[25]	[85]	9	hSpCas9	negative selection	11852753
182866409	182866432	2	+	28162770	MV411	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	1.6501967202831824	[58]	[155]	9	hSpCas9	negative selection	11852754
182866153	182866176	2	+	28162770	MV411	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.5593815570975158	[144]	[179]	5	hSpCas9	negative selection	11852755
182838493	182838516	2	+	28162770	MV411	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.2115179765278326	[121]	[118]	1	hSpCas9	negative selection	11852756
182866343	182866366	2	+	28162770	MV411	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.25626140116978147	[162]	[163]	2	hSpCas9	negative selection	11852757
182866298	182866321	2	+	28162770	MV411	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-1.0300964247461335	[79]	[32]	-6	hSpCas9	negative selection	11852758
182866288	182866311	2	+	28162770	MV411	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.0985741648682924	[101]	[91]	0	hSpCas9	negative selection	11852759
182866478	182866501	2	+	28162770	MONOMAC1	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.09825869258138015	[126]	[135]	-1	hSpCas9	negative selection	12022116
182866099	182866122	2	-	28162770	MONOMAC1	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	1.7074671557120868	[120]	[452]	9	hSpCas9	negative selection	12022117
182866120	182866143	2	-	28162770	MONOMAC1	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.4606819960969166	[115]	[182]	4	hSpCas9	negative selection	12022118
182866509	182866532	2	-	28162770	MONOMAC1	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	0.42745401784824	[23]	[36]	4	hSpCas9	negative selection	12022119
182866409	182866432	2	+	28162770	MONOMAC1	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	0.4403930735557382	[44]	[69]	4	hSpCas9	negative selection	12022120
182866153	182866176	2	+	28162770	MONOMAC1	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	1.061424828984416	[78]	[188]	8	hSpCas9	negative selection	12022121
182838493	182838516	2	+	28162770	MONOMAC1	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	-0.1001753078069646	[71]	[76]	-1	hSpCas9	negative selection	12022122
182866343	182866366	2	+	28162770	MONOMAC1	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.6925391632467959	[94]	[175]	6	hSpCas9	negative selection	12022123
182866298	182866321	2	+	28162770	MONOMAC1	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.24434256183791025	[61]	[59]	-2	hSpCas9	negative selection	12022124
182866288	182866311	2	+	28162770	MONOMAC1	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.7249606409391731	[56]	[107]	7	hSpCas9	negative selection	12022125
182866478	182866501	2	+	28162770	OCIAML2	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-1.1710695433832536	[25]	[63]	-6	hSpCas9	negative selection	12191482
182866099	182866122	2	-	28162770	OCIAML2	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.7931033914751862	[42]	[412]	7	hSpCas9	negative selection	12191483
182866120	182866143	2	-	28162770	OCIAML2	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.7772976882014244	[29]	[284]	7	hSpCas9	negative selection	12191484
182866509	182866532	2	-	28162770	OCIAML2	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	0.9078817980115685	[4]	[51]	8	hSpCas9	negative selection	12191485
182866409	182866432	2	+	28162770	OCIAML2	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	0.4085157798834529	[13]	[102]	4	hSpCas9	negative selection	12191486
182866153	182866176	2	+	28162770	OCIAML2	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	-0.20759541940836726	[39]	[191]	-2	hSpCas9	negative selection	12191487
182838493	182838516	2	+	28162770	OCIAML2	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.32811196651073493	[23]	[166]	3	hSpCas9	negative selection	12191488
182866343	182866366	2	+	28162770	OCIAML2	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	0.6358697960585176	[30]	[266]	6	hSpCas9	negative selection	12191489
182866298	182866321	2	+	28162770	OCIAML2	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-1.2611764596132116	[15]	[36]	-7	hSpCas9	negative selection	12191490
182866288	182866311	2	+	28162770	OCIAML2	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	-1.5737233182062649	[28]	[53]	-7	hSpCas9	negative selection	12191491
182866478	182866501	2	+	28162770	OCIAML3	viability	GAGCAGGCAGAGAGCAGCCAGGG	FRZB	ENSG00000162998	-0.26505911775902846	[40]	[102]	-2	hSpCas9	negative selection	12360848
182866099	182866122	2	-	28162770	OCIAML3	viability	GGGCGTGTGCATCTCTCCCGAGG	FRZB	ENSG00000162998	0.2761549220332554	[60]	[222]	2	hSpCas9	negative selection	12360849
182866120	182866143	2	-	28162770	OCIAML3	viability	GGAGCTGCCAGTGTACGACAGGG	FRZB	ENSG00000162998	0.440262261760583	[51]	[212]	4	hSpCas9	negative selection	12360850
182866509	182866532	2	-	28162770	OCIAML3	viability	GGGATGCTGCTGCTGCGGGCCGG	FRZB	ENSG00000162998	0.2639733548034089	[7]	[28]	2	hSpCas9	negative selection	12360851
182866409	182866432	2	+	28162770	OCIAML3	viability	CCAGGGCAGGGACTTGCACAGGG	FRZB	ENSG00000162998	1.3414521074811263	[19]	[152]	9	hSpCas9	negative selection	12360852
182866153	182866176	2	+	28162770	OCIAML3	viability	GGTTCTCCGGCCACGAGTGGCGG	FRZB	ENSG00000162998	0.5538910547881502	[43]	[194]	5	hSpCas9	negative selection	12360853
182838493	182838516	2	+	28162770	OCIAML3	viability	TAGAGGTTGACAGTGTCCCGTGG	FRZB	ENSG00000162998	0.3050634508250563	[36]	[137]	3	hSpCas9	negative selection	12360854
182866343	182866366	2	+	28162770	OCIAML3	viability	CTCGATGGCCAGGATGGCGTTGG	FRZB	ENSG00000162998	-0.9340830819217848	[49]	[78]	-6	hSpCas9	negative selection	12360855
182866298	182866321	2	+	28162770	OCIAML3	viability	GAGCAGATCGGGGCTGCAGTGGG	FRZB	ENSG00000162998	-0.7143018740418752	[24]	[45]	-5	hSpCas9	negative selection	12360856
182866288	182866311	2	+	28162770	OCIAML3	viability	AGAGGAAGAAGAGCAGATCGGGG	FRZB	ENSG00000162998	0.4701226970955523	[21]	[91]	4	hSpCas9	negative selection	12360857