Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8325
• Symbol:FZD8
• Description:frizzled class receptor 8

DataSource: http://genomecrispr.dkfz.de/#!/results/FZD8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
35640402	35640425	10	-	26472758	Jiyoye	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.4071753815058734	[277]	[277]	3	hSpCas9	negative selection	60768
35640230	35640253	10	+	26472758	Jiyoye	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	-0.5818535006731235	[130]	[65]	-4	hSpCas9	negative selection	60769
35640050	35640073	10	+	26472758	Jiyoye	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	1.4071753815058734	[27]	[55]	8	hSpCas9	negative selection	60770
35641367	35641390	10	+	26472758	Jiyoye	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.8825133910525313	[81]	[113]	6	hSpCas9	negative selection	60771
35641351	35641374	10	-	26472758	Jiyoye	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	1.338462631421859	[42]	[81]	7	hSpCas9	negative selection	60772
35640888	35640911	10	-	26472758	Jiyoye	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	-0.3297902126603328	[204]	[122]	-2	hSpCas9	negative selection	60773
35640584	35640607	10	+	26472758	Jiyoye	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	-0.6306266512065111	[231]	[112]	-4	hSpCas9	negative selection	60774
35640533	35640556	10	+	26472758	Jiyoye	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	-0.9702987048164871	[277]	[106]	-6	hSpCas9	negative selection	60775
35640433	35640456	10	-	26472758	Jiyoye	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.9153222851761986	[89]	[127]	6	hSpCas9	negative selection	60776
35640283	35640306	10	-	26472758	Jiyoye	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-3.4408215250490763	[71]	[4]	-9	hSpCas9	negative selection	60777
35640402	35640425	10	-	26472758	KBM7	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.5053541269738577	[1192,828]	[653,675]	5	hSpCas9	negative selection	251886
35640230	35640253	10	+	26472758	KBM7	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.1954157113966336	[694,519]	[373,278]	2	hSpCas9	negative selection	251887
35640050	35640073	10	+	26472758	KBM7	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	-0.4414904817886218	[297,130]	[58,82]	-4	hSpCas9	negative selection	251888
35641367	35641390	10	+	26472758	KBM7	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.033531242484578894	[503,327]	[180,210]	0	hSpCas9	negative selection	251889
35641351	35641374	10	-	26472758	KBM7	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.677471118268945	[282,184]	[105,232]	7	hSpCas9	negative selection	251890
35640888	35640911	10	-	26472758	KBM7	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.5902396669433045	[753,385]	[436,351]	6	hSpCas9	negative selection	251891
35640584	35640607	10	+	26472758	KBM7	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.18905568487844882	[719,831]	[372,463]	2	hSpCas9	negative selection	251892
35640533	35640556	10	+	26472758	KBM7	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.042326447577939005	[527,470]	[229,251]	0	hSpCas9	negative selection	251893
35640433	35640456	10	-	26472758	KBM7	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.665904026770147	[418,321]	[348,206]	7	hSpCas9	negative selection	251894
35640283	35640306	10	-	26472758	KBM7	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-1.0801902508238657	[408,252]	[77,66]	-7	hSpCas9	negative selection	251895
35640402	35640425	10	-	26472758	Raji	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.5653296261217344	[529]	[181]	5	hSpCas9	negative selection	443004
35640230	35640253	10	+	26472758	Raji	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.18984569556557257	[237]	[62]	1	hSpCas9	negative selection	443005
35640050	35640073	10	+	26472758	Raji	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	0.045099257119256775	[141]	[33]	0	hSpCas9	negative selection	443006
35641367	35641390	10	+	26472758	Raji	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.5989191721264868	[201]	[70]	5	hSpCas9	negative selection	443007
35641351	35641374	10	-	26472758	Raji	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	1.2329144174574584	[98]	[53]	9	hSpCas9	negative selection	443008
35640888	35640911	10	-	26472758	Raji	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.8609456400705006	[241]	[101]	7	hSpCas9	negative selection	443009
35640584	35640607	10	+	26472758	Raji	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	-0.270090550948761	[555]	[106]	-2	hSpCas9	negative selection	443010
35640533	35640556	10	+	26472758	Raji	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.10258254910977821	[300]	[74]	1	hSpCas9	negative selection	443011
35640433	35640456	10	-	26472758	Raji	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	-0.7688102630120026	[278]	[37]	-5	hSpCas9	negative selection	443012
35640283	35640306	10	-	26472758	Raji	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-1.684029842814983	[179]	[12]	-8	hSpCas9	negative selection	443013
35640402	35640425	10	-	26472758	K562	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.13854031505642395	[748]	[695]	1	hSpCas9	negative selection	634122
35640230	35640253	10	+	26472758	K562	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.5803160068597967	[369]	[466]	5	hSpCas9	negative selection	634123
35640050	35640073	10	+	26472758	K562	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	1.447952121751579	[98]	[227]	9	hSpCas9	negative selection	634124
35641367	35641390	10	+	26472758	K562	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.9139934561025443	[297]	[473]	7	hSpCas9	negative selection	634125
35641351	35641374	10	-	26472758	K562	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	1.1168045310820987	[188]	[345]	8	hSpCas9	negative selection	634126
35640888	35640911	10	-	26472758	K562	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.6659872251556853	[550]	[737]	5	hSpCas9	negative selection	634127
35640584	35640607	10	+	26472758	K562	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.3328468334487993	[790]	[840]	2	hSpCas9	negative selection	634128
35640533	35640556	10	+	26472758	K562	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	-0.07387079015756753	[494]	[396]	0	hSpCas9	negative selection	634129
35640433	35640456	10	-	26472758	K562	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	-0.1653438295717227	[363]	[273]	-1	hSpCas9	negative selection	634130
35640283	35640306	10	-	26472758	K562	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-3.1478986951123136	[230]	[21]	-8	hSpCas9	negative selection	634131
35640463	35640486	10	+	26627737	DLD1	viability	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.22835008711379712	[1232]	[470,374,497]	2	hSpCas9	negative selection	774852
35640497	35640520	10	-	26627737	DLD1	viability	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.5799054265249362	[366]	[131,216,167]	6	hSpCas9	negative selection	774853
35640520	35640543	10	-	26627737	DLD1	viability	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.19201010945775443	[1664]	[493,784,523]	2	hSpCas9	negative selection	774854
35640658	35640681	10	+	26627737	DLD1	viability	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.3946694633332961	[1929]	[1001,756,641]	4	hSpCas9	negative selection	774855
35641287	35641310	10	+	26627737	DLD1	viability	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.27828334798230236	[1145]	[546,228,506]	3	hSpCas9	negative selection	774856
35640463	35640486	10	+	26627737	GBM cells	viability after 5 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.24855938818090273	[597]	[401,359]	4	hSpCas9	negative selection	857167
35640497	35640520	10	-	26627737	GBM cells	viability after 5 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.02308361311304108	[305]	[188,133]	0	hSpCas9	negative selection	857168
35640520	35640543	10	-	26627737	GBM cells	viability after 5 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.04637186620368694	[801]	[382,449]	0	hSpCas9	negative selection	857169
35640658	35640681	10	+	26627737	GBM cells	viability after 5 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.15899697718587702	[733]	[429,448]	2	hSpCas9	negative selection	857170
35641287	35641310	10	+	26627737	GBM cells	viability after 5 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.021945346547039835	[673]	[283,449]	0	hSpCas9	negative selection	857171
35640463	35640486	10	+	26627737	GBM cells	viability after 13 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.44614800228840923	[597]	[462,424]	5	hSpCas9	negative selection	939482
35640497	35640520	10	-	26627737	GBM cells	viability after 13 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.3697963711307902	[305]	[256,179]	5	hSpCas9	negative selection	939483
35640520	35640543	10	-	26627737	GBM cells	viability after 13 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.023506941936423553	[801]	[406,470]	0	hSpCas9	negative selection	939484
35640658	35640681	10	+	26627737	GBM cells	viability after 13 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	-0.13344440569194327	[733]	[356,367]	-2	hSpCas9	negative selection	939485
35641287	35641310	10	+	26627737	GBM cells	viability after 13 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.21846380163794477	[673]	[505,359]	3	hSpCas9	negative selection	939486
35640463	35640486	10	+	26627737	GBM cells	viability after 21 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	1.0539775536163056	[597]	[708,642]	9	hSpCas9	negative selection	1021797
35640497	35640520	10	-	26627737	GBM cells	viability after 21 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.04827119151370529	[305]	[185,158]	0	hSpCas9	negative selection	1021798
35640520	35640543	10	-	26627737	GBM cells	viability after 21 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.4669536257037936	[801]	[631,574]	5	hSpCas9	negative selection	1021799
35640658	35640681	10	+	26627737	GBM cells	viability after 21 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	-0.06659747815069217	[733]	[385,375]	0	hSpCas9	negative selection	1021800
35641287	35641310	10	+	26627737	GBM cells	viability after 21 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.011105524494195773	[673]	[368,368]	0	hSpCas9	negative selection	1021801
35640463	35640486	10	+	26627737	RPE1	viability after 9 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.14317051073012066	[1554]	[356,548]	-1	hSpCas9	negative selection	1104112
35640497	35640520	10	-	26627737	RPE1	viability after 9 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.44182963720722807	[1295]	[244,367]	-3	hSpCas9	negative selection	1104113
35640520	35640543	10	-	26627737	RPE1	viability after 9 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.5473077535019892	[2807]	[539,680]	-4	hSpCas9	negative selection	1104114
35640658	35640681	10	+	26627737	RPE1	viability after 9 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	-1.4318934185794547	[3720]	[567,255]	-8	hSpCas9	negative selection	1104115
35641287	35641310	10	+	26627737	RPE1	viability after 9 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.506107590062501	[3470]	[896,594]	-4	hSpCas9	negative selection	1104116
35640463	35640486	10	+	26627737	RPE1	viability after 12 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.01619031334266252	[1554]	[416,408]	0	hSpCas9	negative selection	1186427
35640497	35640520	10	-	26627737	RPE1	viability after 12 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.8052509593797488	[1295]	[156,243]	-5	hSpCas9	negative selection	1186428
35640520	35640543	10	-	26627737	RPE1	viability after 12 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.2086554197637538	[2807]	[663,640]	-1	hSpCas9	negative selection	1186429
35640658	35640681	10	+	26627737	RPE1	viability after 12 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	-0.886640600637145	[3720]	[717,352]	-6	hSpCas9	negative selection	1186430
35641287	35641310	10	+	26627737	RPE1	viability after 12 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.4541792165183749	[3470]	[805,547]	-3	hSpCas9	negative selection	1186431
35640463	35640486	10	+	26627737	RPE1	viability after 15 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.10169281726795043	[1554]	[300,514]	0	hSpCas9	negative selection	1268742
35640497	35640520	10	-	26627737	RPE1	viability after 15 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.2169463770487422	[1295]	[403,229]	-1	hSpCas9	negative selection	1268743
35640520	35640543	10	-	26627737	RPE1	viability after 15 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.4830786308553965	[2807]	[410,719]	-3	hSpCas9	negative selection	1268744
35640658	35640681	10	+	26627737	RPE1	viability after 15 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	-0.8369703706825498	[3720]	[855,331]	-5	hSpCas9	negative selection	1268745
35641287	35641310	10	+	26627737	RPE1	viability after 15 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.16848001735235063	[3470]	[780,962]	-1	hSpCas9	negative selection	1268746
35640463	35640486	10	+	26627737	RPE1	viability after 18 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.2631485175473165	[1554]	[281,421]	-2	hSpCas9	negative selection	1351057
35640497	35640520	10	-	26627737	RPE1	viability after 18 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.10454001754166131	[1295]	[202,455]	0	hSpCas9	negative selection	1351058
35640520	35640543	10	-	26627737	RPE1	viability after 18 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.3364528680818921	[2807]	[327,890]	-2	hSpCas9	negative selection	1351059
35640658	35640681	10	+	26627737	RPE1	viability after 18 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	-0.7333903555171197	[3720]	[778,416]	-4	hSpCas9	negative selection	1351060
35641287	35641310	10	+	26627737	RPE1	viability after 18 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.4307162830728528	[3470]	[736,649]	-3	hSpCas9	negative selection	1351061
35640463	35640486	10	+	26627737	HeLa	viability after 8 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.6237963856012367	[744]	[402,554,517]	5	hSpCas9	negative selection	1433372
35640497	35640520	10	-	26627737	HeLa	viability after 8 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.46204395468646453	[587]	[308,113,162]	-4	hSpCas9	negative selection	1433373
35640520	35640543	10	-	26627737	HeLa	viability after 8 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.25444312949077164	[839]	[283,634,360]	2	hSpCas9	negative selection	1433374
35640658	35640681	10	+	26627737	HeLa	viability after 8 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.5548131446443028	[1203]	[953,960,456]	5	hSpCas9	negative selection	1433375
35641287	35641310	10	+	26627737	HeLa	viability after 8 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.10742182462890981	[951]	[427,359,539]	1	hSpCas9	negative selection	1433376
35640463	35640486	10	+	26627737	HeLa	viability after 12 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.7714286158824002	[744]	[566,372,653]	6	hSpCas9	negative selection	1515687
35640497	35640520	10	-	26627737	HeLa	viability after 12 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.06323128264445688	[587]	[418,144,213]	0	hSpCas9	negative selection	1515688
35640520	35640543	10	-	26627737	HeLa	viability after 12 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.41572350298770067	[839]	[382,565,426]	3	hSpCas9	negative selection	1515689
35640658	35640681	10	+	26627737	HeLa	viability after 12 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.35895089361652044	[1203]	[638,660,611]	3	hSpCas9	negative selection	1515690
35641287	35641310	10	+	26627737	HeLa	viability after 12 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.13892735449636184	[951]	[392,323,592]	1	hSpCas9	negative selection	1515691
35640463	35640486	10	+	26627737	HeLa	viability after 15 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.7223165339422701	[744]	[740,244,512]	5	hSpCas9	negative selection	1598002
35640497	35640520	10	-	26627737	HeLa	viability after 15 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.13902276445813433	[587]	[409,125,251]	1	hSpCas9	negative selection	1598003
35640520	35640543	10	-	26627737	HeLa	viability after 15 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.38155990385036054	[839]	[295,601,439]	3	hSpCas9	negative selection	1598004
35640658	35640681	10	+	26627737	HeLa	viability after 15 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.3811206019326656	[1203]	[536,684,698]	3	hSpCas9	negative selection	1598005
35641287	35641310	10	+	26627737	HeLa	viability after 15 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.0033493133407951348	[951]	[340,451,365]	0	hSpCas9	negative selection	1598006
35640463	35640486	10	+	26627737	HeLa	viability after 18 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.7006921896711107	[744]	[488,194,512]	5	hSpCas9	negative selection	1680317
35640497	35640520	10	-	26627737	HeLa	viability after 18 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.18127493505863312	[587]	[292,100,251]	1	hSpCas9	negative selection	1680318
35640520	35640543	10	-	26627737	HeLa	viability after 18 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.36383141251580997	[839]	[189,495,439]	3	hSpCas9	negative selection	1680319
35640658	35640681	10	+	26627737	HeLa	viability after 18 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.3644473534641566	[1203]	[350,560,698]	3	hSpCas9	negative selection	1680320
35641287	35641310	10	+	26627737	HeLa	viability after 18 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.0010761779663039928	[951]	[238,362,365]	0	hSpCas9	negative selection	1680321
35640463	35640486	10	+	26627737	HCT116	viability after 6 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	1.1575501252139375	[1818]	[1023,424]	6	hSpCas9	negative selection	1762632
35640497	35640520	10	-	26627737	HCT116	viability after 6 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	1.0635809621676835	[846]	[296,267]	6	hSpCas9	negative selection	1762633
35640520	35640543	10	-	26627737	HCT116	viability after 6 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.31236763463807815	[1856]	[658,198]	1	hSpCas9	negative selection	1762634
35640658	35640681	10	+	26627737	HCT116	viability after 6 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.7042345975499755	[2003]	[1026,229]	4	hSpCas9	negative selection	1762635
35641287	35641310	10	+	26627737	HCT116	viability after 6 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	1.0692912681931228	[1624]	[430,593]	6	hSpCas9	negative selection	1762636
35640463	35640486	10	+	26627737	HCT116	viability after 8 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.637858014435684	[1349]	[547,453,433]	-7	hSpCas9	negative selection	1844947
35640497	35640520	10	-	26627737	HCT116	viability after 8 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.08360817343731664	[435]	[275,222,264]	1	hSpCas9	negative selection	1844948
35640520	35640543	10	-	26627737	HCT116	viability after 8 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.03361405530596717	[939]	[477,565,473]	0	hSpCas9	negative selection	1844949
35640658	35640681	10	+	26627737	HCT116	viability after 8 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.6470119818624185	[722]	[691,575,604]	6	hSpCas9	negative selection	1844950
35641287	35641310	10	+	26627737	HCT116	viability after 8 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.1331255482253937	[543]	[425,237,323]	1	hSpCas9	negative selection	1844951
35640463	35640486	10	+	26627737	HCT116	viability after 9 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.49417849970244054	[1818]	[701,669]	3	hSpCas9	negative selection	1927262
35640497	35640520	10	-	26627737	HCT116	viability after 9 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.40740985598904744	[846]	[217,132]	-3	hSpCas9	negative selection	1927263
35640520	35640543	10	-	26627737	HCT116	viability after 9 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.9505476380694424	[1856]	[821,1065]	6	hSpCas9	negative selection	1927264
35640658	35640681	10	+	26627737	HCT116	viability after 9 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.919637635504156	[2003]	[494,1420]	6	hSpCas9	negative selection	1927265
35641287	35641310	10	+	26627737	HCT116	viability after 9 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.7687063135959191	[1624]	[855,646]	5	hSpCas9	negative selection	1927266
35640463	35640486	10	+	26627737	HCT116	viability after 12 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.6924422104743408	[1349]	[495,436,378]	-6	hSpCas9	negative selection	2009577
35640497	35640520	10	-	26627737	HCT116	viability after 12 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.020411248747076227	[435]	[189,194,314]	0	hSpCas9	negative selection	2009578
35640520	35640543	10	-	26627737	HCT116	viability after 12 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.19309563393688944	[939]	[384,453,461]	-2	hSpCas9	negative selection	2009579
35640658	35640681	10	+	26627737	HCT116	viability after 12 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.7218910501021911	[722]	[607,598,673]	6	hSpCas9	negative selection	2009580
35641287	35641310	10	+	26627737	HCT116	viability after 12 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.40249811802011615	[543]	[397,258,471]	4	hSpCas9	negative selection	2009581
35640463	35640486	10	+	26627737	HCT116	viability after 15 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-1.0865096107404484	[1349]	[301,371,412]	-8	hSpCas9	negative selection	2091892
35640497	35640520	10	-	26627737	HCT116	viability after 15 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.25268094319847223	[435]	[411,131,363]	2	hSpCas9	negative selection	2091893
35640520	35640543	10	-	26627737	HCT116	viability after 15 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.07230122971202357	[939]	[500,572,619]	0	hSpCas9	negative selection	2091894
35640658	35640681	10	+	26627737	HCT116	viability after 15 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.5249224719083567	[722]	[457,691,624]	5	hSpCas9	negative selection	2091895
35641287	35641310	10	+	26627737	HCT116	viability after 15 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.37927011556372947	[543]	[504,313,411]	3	hSpCas9	negative selection	2091896
35640463	35640486	10	+	26627737	HCT116	viability after 18 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.6376169688645912	[1349]	[356,269,651]	-5	hSpCas9	negative selection	2174207
35640497	35640520	10	-	26627737	HCT116	viability after 18 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.686611761342563	[435]	[81,132,179]	-6	hSpCas9	negative selection	2174208
35640520	35640543	10	-	26627737	HCT116	viability after 18 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.21544706325635743	[939]	[368,410,392]	-2	hSpCas9	negative selection	2174209
35640658	35640681	10	+	26627737	HCT116	viability after 18 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.38114769639123547	[722]	[426,309,646]	3	hSpCas9	negative selection	2174210
35641287	35641310	10	+	26627737	HCT116	viability after 18 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.11115286114778677	[543]	[239,231,259]	-1	hSpCas9	negative selection	2174211
35641359	35641382	10	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GCGCTGCTGCAGCGCTCTAGCGG	FZD8	ENSG00000177283	0.45111007153824956	[1934,1660,1936]	[0,0,0]	1	hSpCas9	positive selection	2380862
35641351	35641376	10	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CTGCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	-0.6696373328967097	[4158,4136,3732]	[0,0,0]	-6	hSpCas9	positive selection	2380863
35641297	35641321	10	-	24717434	HeLa	essential genes for diphteria toxin toxicity	AGATCACCGTGCCGCTGTGTAAGG	FZD8	ENSG00000177283	-0.4227142297860691	[3430,3337,3361]	[0,0,0]	-4	hSpCas9	positive selection	2380864
35641359	35641382	10	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGCTGCTGCAGCGCTCTAGCGG	FZD8	ENSG00000177283	0.45127328619135104	[1934,1660,1936]	[0,0,0]	1	hSpCas9	positive selection	2382094
35641351	35641376	10	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	-0.6700762856854356	[4158,4136,3732]	[0,0,0]	-6	hSpCas9	positive selection	2382095
35641297	35641321	10	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGATCACCGTGCCGCTGTGTAAGG	FZD8	ENSG00000177283	-0.42288943499612736	[3430,3337,3361]	[0,0,0]	-5	hSpCas9	positive selection	2382096
35641535	35641558	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTCCCTTATGCTTCGCCCGG	FZD8	ENSG00000177283	1.9747002769020938	[199,94]	[57,201]	7	dCas9-VP64	positive selection	2458505
35641507	35641530	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCGCTGTACCCGTCTGCGG	FZD8	ENSG00000177283	0.23085850110860062	[86,524]	[22,140]	1	dCas9-VP64	positive selection	2458506
35641582	35641605	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGGACGCGCCCCTAGAAGGGG	FZD8	ENSG00000177283	0.4235661398164998	[14,0]	[1,1]	1	dCas9-VP64	positive selection	2458507
35641535	35641558	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTCCCTTATGCTTCGCCCGG	FZD8	ENSG00000177283	-0.23218260837849336	[86,69]	[22,19]	-2	dCas9-VP64	positive selection	2553760
35641507	35641530	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCGCTGTACCCGTCTGCGG	FZD8	ENSG00000177283	0.8354224717314052	[130,387]	[51,241]	5	dCas9-VP64	positive selection	2553761
35641582	35641605	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGGACGCGCCCCTAGAAGGGG	FZD8	ENSG00000177283	0.27157558249195324	[17,39]	[5,15]	2	dCas9-VP64	positive selection	2553762
35640707	35640730	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.08733276709791477	[2,2]	[3,1]	1	hSpCas9	positive selection	2989623
35641135	35641158	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACACGCCCATCTGCCTAGAGG	FZD8	ENSG00000177283	-0.49012250268045976	[3,3]	[2,1]	-6	hSpCas9	positive selection	2989624
35641288	35641311	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.6966285639428637	[4,3]	[2,0]	-8	hSpCas9	positive selection	2989625
35640707	35640730	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.4458014383451028	[2,2]	[2,0]	-6	hSpCas9	positive selection	3057481
35641135	35641158	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACACGCCCATCTGCCTAGAGG	FZD8	ENSG00000177283	0.18455444708339752	[3,3]	[3,2]	3	hSpCas9	positive selection	3057482
35641288	35641311	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.40546110786953327	[4,4]	[2,1]	-6	hSpCas9	positive selection	3057483
35640706	35640729		+	24336571	A375	resistance to PLX after 7 days	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.07966277612258577	[14,16]	[16,12]	-2	hSpCas9	positive selection	3115615
35640683	35640706		+	24336571	A375	resistance to PLX after 7 days	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.3173030097639986	[7,7]	[6,4]	-8	hSpCas9	positive selection	3115616
35640706	35640729		+	24336571	A375	resistance to PLX after 14 days	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.49667415563906575	[15,19]	[5,4]	-6	hSpCas9	positive selection	3173408
35640683	35640706		+	24336571	A375	resistance to PLX after 14 days	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.3445434389961	[8,10]	[3,2]	-4	hSpCas9	positive selection	3173409
35640706	35640729		+	24336571	A375	viability after 7 days	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.4057922437576182	[12]	[14,16]	6	hSpCas9	negative selection	3231201
35640683	35640706		+	24336571	A375	viability after 7 days	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.32704528791600107	[5]	[7,7]	5	hSpCas9	negative selection	3231202
35640706	35640729		+	24336571	A375	viability after 14 days	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.5701578532210961	[12]	[15,19]	7	hSpCas9	negative selection	3288994
35640683	35640706		+	24336571	A375	viability after 14 days	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.6943941407114709	[5]	[8,10]	8	hSpCas9	negative selection	3288995
35640683	35640706	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	3.0138721745815578	[9,27]	[0,0]	8	hSpCas9	positive selection	3350781
35640706	35640729	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.2923719508893744	[113,135]	[0,0]	1	hSpCas9	positive selection	3350782
35639794	35639817	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	1.0211087470813667	[57,92]	[0,0]	4	hSpCas9	positive selection	3350783
35640448	35640471	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	1.2129320920873818	[65,65]	[0,0]	5	hSpCas9	positive selection	3369990
35639415	35639438	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.29726264023180216	[187,187]	[0,0]	-2	hSpCas9	positive selection	3369991
35640715	35640738	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.4371472490306473	[112,112]	[0,0]	2	hSpCas9	positive selection	3369992
35640706	35640729	10	+	26780180	HT29	viability (Avana library 4 designs)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	1.65418918669862	[]	[]	6	hSpCas9	negative selection	3426584
35641135	35641158	10	-	26780180	HT29	viability (Avana library 4 designs)	GTACACGCCCATCTGCCTAGAGG	FZD8	ENSG00000177283	-0.0457995116135137	[]	[]	0	hSpCas9	negative selection	3426585
35641287	35641310	10	+	26780180	HT29	viability (Avana library 4 designs)	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	1.13966874774927	[]	[]	4	hSpCas9	negative selection	3426586
35641287	35641310	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	2.60451774507561	[]	[]	4	hSpCas9	negative selection	3509318
35640706	35640729	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	3.44255323947423	[]	[]	5	hSpCas9	negative selection	3509319
35641135	35641158	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACACGCCCATCTGCCTAGAGG	FZD8	ENSG00000177283	1.79041443556075	[]	[]	2	hSpCas9	negative selection	3509320
35641351	35641374	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	2.69616336496184	[]	[]	4	hSpCas9	negative selection	3509321
35640578	35640601	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACAGGCCGATCCAGAAGACGG	FZD8	ENSG00000177283	4.2409971903392	[]	[]	7	hSpCas9	negative selection	3509322
35641287	35641310	10	+	26780180	A375	viability (Avana lentiGuide)	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-1.22329507824308	[]	[]	-2	hSpCas9	negative selection	3617977
35640706	35640729	10	+	26780180	A375	viability (Avana lentiGuide)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-1.06054093511509	[]	[]	-2	hSpCas9	negative selection	3617978
35641135	35641158	10	-	26780180	A375	viability (Avana lentiGuide)	GTACACGCCCATCTGCCTAGAGG	FZD8	ENSG00000177283	-4.64446181450622	[]	[]	-7	hSpCas9	negative selection	3617979
35641351	35641374	10	-	26780180	A375	viability (Avana lentiGuide)	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	6.23131055961895	[]	[]	5	hSpCas9	negative selection	3617980
35640578	35640601	10	+	26780180	A375	viability (Avana lentiGuide)	CCACAGGCCGATCCAGAAGACGG	FZD8	ENSG00000177283	-5.73747910220292	[]	[]	-8	hSpCas9	negative selection	3617981
35641287	35641310	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.05062542897501343	[5]	[5,4]	1	hSpCas9	positive selection	3726636
35640706	35640729	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.28413478080141014	[4]	[5,4]	8	hSpCas9	positive selection	3726637
35641135	35641158	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACACGCCCATCTGCCTAGAGG	FZD8	ENSG00000177283	0.06565880653936951	[4]	[5,4]	1	hSpCas9	positive selection	3726638
35641351	35641374	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.3819355122866592	[3]	[4,4]	9	hSpCas9	positive selection	3726639
35640578	35640601	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACAGGCCGATCCAGAAGACGG	FZD8	ENSG00000177283	0.2324355764334524	[4]	[4,4]	6	hSpCas9	positive selection	3726640
35641287	35641310	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.16894522704551324	[5]	[4,5]	4	hSpCas9	positive selection	3835243
35640706	35640729	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.3368657821423062	[4]	[3,2]	-4	hSpCas9	positive selection	3835244
35641135	35641158	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACACGCCCATCTGCCTAGAGG	FZD8	ENSG00000177283	0.31357672803769393	[5]	[6,5]	8	hSpCas9	positive selection	3835245
35641351	35641374	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.21846163531028517	[5]	[5,5]	5	hSpCas9	positive selection	3835246
35640578	35640601	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACAGGCCGATCCAGAAGACGG	FZD8	ENSG00000177283	-0.5982207595709799	[4]	[1,2]	-6	hSpCas9	positive selection	3835247
35640706	35640729	10	+	26780180	A375	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	1.43262894280028	[]	[]	8	hSpCas9	negative selection	3942409
35639415	35639438	10	-	26780180	A375	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	1.40221642714773	[]	[]	7	hSpCas9	negative selection	3942410
35639794	35639817	10	-	26780180	A375	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	1.11233694631381	[]	[]	5	hSpCas9	negative selection	3942411
35640448	35640471	10	+	26780180	A375	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.969941840204253	[]	[]	4	hSpCas9	negative selection	3942412
35640683	35640706	10	+	26780180	A375	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.112044970241068	[]	[]	0	hSpCas9	negative selection	3942413
35640715	35640738	10	-	26780180	A375	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	1.54829441962909	[]	[]	8	hSpCas9	negative selection	3942414
35640706	35640729	10	+	26780180	HT29	viability (GeCKOv2 library)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	1.49329839262745	[]	[]	7	hSpCas9	negative selection	4050375
35639415	35639438	10	-	26780180	HT29	viability (GeCKOv2 library)	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.613902272567296	[]	[]	2	hSpCas9	negative selection	4050376
35639794	35639817	10	-	26780180	HT29	viability (GeCKOv2 library)	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.113707988468369	[]	[]	0	hSpCas9	negative selection	4050377
35640448	35640471	10	+	26780180	HT29	viability (GeCKOv2 library)	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.914206835256477	[]	[]	4	hSpCas9	negative selection	4050378
35640683	35640706	10	+	26780180	HT29	viability (GeCKOv2 library)	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.544583042212902	[]	[]	1	hSpCas9	negative selection	4050379
35640715	35640738	10	-	26780180	HT29	viability (GeCKOv2 library)	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	1.2877078123695	[]	[]	6	hSpCas9	negative selection	4050380
35640706	35640729	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.13892245456360527	[3]	[2,2]	3	hSpCas9	positive selection	4138743
35640683	35640706	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.12936175320438908	[2]	[1,1]	-3	hSpCas9	positive selection	4138744
35640706	35640729	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.34295296707918466	[3]	[3,2,2,0]	2	hSpCas9	positive selection	4202765
35640683	35640706	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.682872241077741	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4202766
35640683	35640706	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.044637972039200946	[0]	[0,0]	-1	hSpCas9	positive selection	4271972
35640706	35640729	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.10493722064058446	[2]	[2,2]	2	hSpCas9	positive selection	4271973
35639794	35639817	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.05218489866934098	[2]	[2,1]	1	hSpCas9	positive selection	4271974
35640448	35640471	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.20805520244818743	[1]	[1,1]	4	hSpCas9	positive selection	4336233
35639415	35639438	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.14793712639347412	[3]	[3,2]	3	hSpCas9	positive selection	4336234
35640715	35640738	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.23353117046608549	[2]	[2,1]	-5	hSpCas9	positive selection	4336235
35640454	35640476	10	-	27760321	OCIAML3	viability	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.34309219727922224	[747,742]	[588,940]	4	hSpCas9	negative selection	4402465
35640644	35640666	10	+	27760321	OCIAML3	viability	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	-0.22171838150479903	[535,480]	[334,347]	-2	hSpCas9	negative selection	4402466
35640674	35640696	10	+	27760321	OCIAML3	viability	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.2013001651088675	[544,459]	[322,615]	2	hSpCas9	negative selection	4402467
35640713	35640735	10	+	27760321	OCIAML3	viability	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	0.010841735103073735	[514,515]	[384,436]	0	hSpCas9	negative selection	4402468
35641016	35641038	10	+	27760321	OCIAML3	viability	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.07622920384428378	[1034,811]	[623,928]	0	hSpCas9	negative selection	4402469
35640454	35640476	10	-	27760321	OCIAML2	viability	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.4525090196755259	[747,742]	[655,1053]	6	hSpCas9	negative selection	4485928
35640644	35640666	10	+	27760321	OCIAML2	viability	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	-0.405878018678939	[535,480]	[291,333]	-5	hSpCas9	negative selection	4485929
35640674	35640696	10	+	27760321	OCIAML2	viability	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.4344679312282889	[544,459]	[517,585]	6	hSpCas9	negative selection	4485930
35640713	35640735	10	+	27760321	OCIAML2	viability	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	0.19209836616496953	[514,515]	[433,535]	2	hSpCas9	negative selection	4485931
35641016	35641038	10	+	27760321	OCIAML2	viability	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.039610043579990206	[1034,811]	[710,830]	0	hSpCas9	negative selection	4485932
35640454	35640476	10	-	27760321	MV411	viability	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.4337319412932701	[747,742]	[781,492]	3	hSpCas9	negative selection	4569391
35640644	35640666	10	+	27760321	MV411	viability	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	-0.7042445640359677	[535,480]	[104,356]	-5	hSpCas9	negative selection	4569392
35640674	35640696	10	+	27760321	MV411	viability	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.5444988304653056	[544,459]	[329,709]	4	hSpCas9	negative selection	4569393
35640713	35640735	10	+	27760321	MV411	viability	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.43055488614107873	[514,515]	[76,517]	-3	hSpCas9	negative selection	4569394
35641016	35641038	10	+	27760321	MV411	viability	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.43496451637933364	[1034,811]	[576,1180]	3	hSpCas9	negative selection	4569395
35640454	35640476	10	-	27760321	HL60	viability	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.35641132831563094	[747,742]	[764,799]	4	hSpCas9	negative selection	4652854
35640644	35640666	10	+	27760321	HL60	viability	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	0.09177992549327868	[535,480]	[380,506]	1	hSpCas9	negative selection	4652855
35640674	35640696	10	+	27760321	HL60	viability	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	-0.3807821005426491	[544,459]	[300,327]	-4	hSpCas9	negative selection	4652856
35640713	35640735	10	+	27760321	HL60	viability	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	0.0877740904447337	[514,515]	[399,500]	1	hSpCas9	negative selection	4652857
35641016	35641038	10	+	27760321	HL60	viability	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.3056920608567639	[1034,811]	[917,934]	4	hSpCas9	negative selection	4652858
35640454	35640476	10	-	27760321	HT1080	viability	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.17340087751533384	[742,579]	[300,292]	0	hSpCas9	negative selection	4736317
35640644	35640666	10	+	27760321	HT1080	viability	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	-1.7495709045214338	[480,375]	[66,32]	-6	hSpCas9	negative selection	4736318
35640674	35640696	10	+	27760321	HT1080	viability	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	1.1331580464220266	[459,358]	[395,315]	6	hSpCas9	negative selection	4736319
35640713	35640735	10	+	27760321	HT1080	viability	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.6628729902175627	[515,402]	[54,181]	-3	hSpCas9	negative selection	4736320
35641016	35641038	10	+	27760321	HT1080	viability	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.34974238458549123	[811,633]	[367,365]	1	hSpCas9	negative selection	4736321
35640454	35640476	10	-	27760321	HT29	viability after 7 days	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	-0.3290490370124417	[742,579]	[714,846,479]	-5	hSpCas9	negative selection	4819780
35640644	35640666	10	+	27760321	HT29	viability after 7 days	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	0.05984337760828168	[480,375]	[661,414,654]	0	hSpCas9	negative selection	4819781
35640674	35640696	10	+	27760321	HT29	viability after 7 days	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	-0.16261476861297192	[459,358]	[673,565,207]	-2	hSpCas9	negative selection	4819782
35640713	35640735	10	+	27760321	HT29	viability after 7 days	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.46553915737674567	[515,402]	[433,394,453]	-6	hSpCas9	negative selection	4819783
35641016	35641038	10	+	27760321	HT29	viability after 7 days	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.33146693935945404	[811,633]	[1437,916,1189]	5	hSpCas9	negative selection	4819784
35640454	35640476	10	-	27760321	HT29	viability after 25 days	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.09130904525139127	[742,579]	[803,641,987]	0	hSpCas9	negative selection	4903243
35640644	35640666	10	+	27760321	HT29	viability after 25 days	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	-0.11254214017344472	[480,375]	[316,319,761]	-1	hSpCas9	negative selection	4903244
35640674	35640696	10	+	27760321	HT29	viability after 25 days	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.3986050209910794	[459,358]	[600,501,762]	4	hSpCas9	negative selection	4903245
35640713	35640735	10	+	27760321	HT29	viability after 25 days	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.4857428166685107	[515,402]	[404,278,445]	-4	hSpCas9	negative selection	4903246
35641016	35641038	10	+	27760321	HT29	viability after 25 days	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.6385646866990156	[811,633]	[1301,1009,1573]	7	hSpCas9	negative selection	4903247
35640454	35640476	10	-	27760321	HT29	viability after 22 days	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.08873755786810633	[742,579]	[1039,641,750]	0	hSpCas9	negative selection	4986706
35640644	35640666	10	+	27760321	HT29	viability after 22 days	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	0.1279541152907107	[480,375]	[597,538,484]	1	hSpCas9	negative selection	4986707
35640674	35640696	10	+	27760321	HT29	viability after 22 days	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.45110954156544036	[459,358]	[667,516,756]	5	hSpCas9	negative selection	4986708
35640713	35640735	10	+	27760321	HT29	viability after 22 days	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.2932153861678353	[515,402]	[400,407,492]	-3	hSpCas9	negative selection	4986709
35641016	35641038	10	+	27760321	HT29	viability after 22 days	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.8557970216845183	[811,633]	[1458,1402,1678]	8	hSpCas9	negative selection	4986710
35640454	35640476	10	-	27760321	HT29	viability after 19 days	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.2525913371353147	[742,579]	[1058,1031,638]	2	hSpCas9	negative selection	5070169
35640644	35640666	10	+	27760321	HT29	viability after 19 days	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	-0.661524653403254	[480,375]	[391,424,127]	-5	hSpCas9	negative selection	5070170
35640674	35640696	10	+	27760321	HT29	viability after 19 days	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	-0.0649548270779284	[459,358]	[689,358,323]	0	hSpCas9	negative selection	5070171
35640713	35640735	10	+	27760321	HT29	viability after 19 days	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.43650979500244774	[515,402]	[508,430,242]	-4	hSpCas9	negative selection	5070172
35641016	35641038	10	+	27760321	HT29	viability after 19 days	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.4979290945474051	[811,633]	[1324,1243,957]	5	hSpCas9	negative selection	5070173
35640454	35640476	10	-	27760321	HT29	viability after 16 days	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.1265049525749108	[742,579]	[1111,668,674]	1	hSpCas9	negative selection	5153632
35640644	35640666	10	+	27760321	HT29	viability after 16 days	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	-0.16607507410957456	[480,375]	[315,594,355]	-2	hSpCas9	negative selection	5153633
35640674	35640696	10	+	27760321	HT29	viability after 16 days	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.36637032337905195	[459,358]	[623,508,643]	4	hSpCas9	negative selection	5153634
35640713	35640735	10	+	27760321	HT29	viability after 16 days	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.47270242352750824	[515,402]	[443,305,369]	-5	hSpCas9	negative selection	5153635
35641016	35641038	10	+	27760321	HT29	viability after 16 days	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	1.0543621578770153	[811,633]	[1522,1364,2144]	9	hSpCas9	negative selection	5153636
35640454	35640476	10	-	27760321	HT29	viability after 13 days	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	-0.06549157493224544	[742,579]	[665,798,734]	-1	hSpCas9	negative selection	5237095
35640644	35640666	10	+	27760321	HT29	viability after 13 days	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	0.06339552493763545	[480,375]	[528,486,540]	0	hSpCas9	negative selection	5237096
35640674	35640696	10	+	27760321	HT29	viability after 13 days	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.4332286448780056	[459,358]	[753,545,624]	5	hSpCas9	negative selection	5237097
35640713	35640735	10	+	27760321	HT29	viability after 13 days	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.5863261821543599	[515,402]	[408,198,450]	-6	hSpCas9	negative selection	5237098
35641016	35641038	10	+	27760321	HT29	viability after 13 days	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.7113563578462263	[811,633]	[1223,1280,1600]	8	hSpCas9	negative selection	5237099
35640454	35640476	10	-	27760321	HT29	viability after 10 days	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	-0.07646394387688205	[742,579]	[687,890,773]	-1	hSpCas9	negative selection	5320558
35640644	35640666	10	+	27760321	HT29	viability after 10 days	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	0.022687454150504216	[480,375]	[403,414,801]	0	hSpCas9	negative selection	5320559
35640674	35640696	10	+	27760321	HT29	viability after 10 days	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.5322423602647782	[459,358]	[592,742,878]	7	hSpCas9	negative selection	5320560
35640713	35640735	10	+	27760321	HT29	viability after 10 days	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	-0.3120944594654538	[515,402]	[501,377,502]	-4	hSpCas9	negative selection	5320561
35641016	35641038	10	+	27760321	HT29	viability after 10 days	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.3640272702664673	[811,633]	[1103,1141,1236]	5	hSpCas9	negative selection	5320562
35640454	35640476	10	-	27760321	MOLM13	viability	TGCTACCTCTTCGTGTCGGTGG	FZD8	ENSG00000177283	0.3525157289322749	[747,742]	[603,482]	2	hSpCas9	negative selection	5404021
35640644	35640666	10	+	27760321	MOLM13	viability	CAGCGCGCAGTTAGCGATCTGG	FZD8	ENSG00000177283	0.09575636659882969	[535,480]	[282,325]	0	hSpCas9	negative selection	5404022
35640674	35640696	10	+	27760321	MOLM13	viability	GACGCGGTTGTAGAGCGGGTGG	FZD8	ENSG00000177283	0.013583233531556993	[544,459]	[410,177]	0	hSpCas9	negative selection	5404023
35640713	35640735	10	+	27760321	MOLM13	viability	CACCATAGGCGCGCGGCACTGG	FZD8	ENSG00000177283	0.33300945871577625	[514,515]	[473,276]	2	hSpCas9	negative selection	5404024
35641016	35641038	10	+	27760321	MOLM13	viability	CAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.02476484441208071	[1034,811]	[720,360]	0	hSpCas9	negative selection	5404025
35640993	35641016	10	+	27661255	K562	viability	GTGTCAGGGTTGCCTTGCTCGGG	FZD8	ENSG00000177283	0.2974860085018279	[415,466]	[492,380]	8	dCas9-KRAB	negative selection	5481169
35641015	35641038	10	+	27661255	K562	viability	GCAGCCGGTCGCAGCGCATGCGG	FZD8	ENSG00000177283	0.2954900834407793	[538,691]	[705,510]	8	dCas9-KRAB	negative selection	5481170
35641419	35641442	10	-	27661255	K562	viability	GAGGCGCACAGCATGGAGTGGGG	FZD8	ENSG00000177283	0.30713783712489373	[983,1249]	[1055,1135]	8	dCas9-KRAB	negative selection	5481171
35640683	35640706	10	+	27260156	BXPC3	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.6717585227271328	[47]	[53,110,67,87]	9	hSpCas9	negative selection	5544432
35640706	35640729	10	+	27260156	BXPC3	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.15002380681361638	[447]	[453,541,524,565]	3	hSpCas9	negative selection	5544433
35639794	35639817	10	-	27260156	BXPC3	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.01378594713569481	[307]	[331,320,354,256]	0	hSpCas9	negative selection	5544434
35640448	35640471	10	+	27260156	BXPC3	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.3729252273128114	[163]	[158,316,141,274]	7	hSpCas9	negative selection	5608693
35639415	35639438	10	-	27260156	BXPC3	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.09599546624169264	[725]	[666,567,796,833]	-2	hSpCas9	negative selection	5608694
35640715	35640738	10	-	27260156	BXPC3	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.0895494067315329	[436]	[441,478,403,638]	2	hSpCas9	negative selection	5608695
35640683	35640706	10	+	27260156	A673	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.8110425550833025	[47]	[102,76,107,117]	9	hSpCas9	negative selection	5665683
35640706	35640729	10	+	27260156	A673	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.1423410768352133	[447]	[540,417,529,465]	-4	hSpCas9	negative selection	5665684
35639794	35639817	10	-	27260156	A673	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.3734232220678936	[307]	[310,281,259,291]	-7	hSpCas9	negative selection	5665685
35640448	35640471	10	+	27260156	A673	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.22501594685066184	[163]	[242,206,214,258]	5	hSpCas9	negative selection	5729944
35639415	35639438	10	-	27260156	A673	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.2603400676449661	[725]	[716,682,710,802]	-6	hSpCas9	negative selection	5729945
35640715	35640738	10	-	27260156	A673	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.0010841475356402341	[436]	[564,571,565,391]	0	hSpCas9	negative selection	5729946
35640683	35640706	10	+	27260156	A375	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.5032065330126212	[47]	[22,109,86,98]	7	hSpCas9	negative selection	5786934
35640706	35640729	10	+	27260156	A375	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.08024791710425622	[447]	[420,752,644,432]	1	hSpCas9	negative selection	5786935
35639794	35639817	10	-	27260156	A375	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.08515563049493857	[307]	[245,539,271,325]	-1	hSpCas9	negative selection	5786936
35640448	35640471	10	+	27260156	A375	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.26802256696751803	[163]	[236,260,335,106]	4	hSpCas9	negative selection	5851195
35639415	35639438	10	-	27260156	A375	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.017994596514793515	[725]	[677,1126,912,685]	0	hSpCas9	negative selection	5851196
35640715	35640738	10	-	27260156	A375	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.17754507592899593	[436]	[394,697,298,445]	-3	hSpCas9	negative selection	5851197
35640683	35640706	10	+	27260156	COLO741	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.8248339875568731	[47]	[87,113,120]	9	hSpCas9	negative selection	5908185
35640706	35640729	10	+	27260156	COLO741	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.0584717764275534	[447]	[464,628,546]	-1	hSpCas9	negative selection	5908186
35639794	35639817	10	-	27260156	COLO741	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.12078355716904798	[307]	[327,375,376]	-3	hSpCas9	negative selection	5908187
35640448	35640471	10	+	27260156	COLO741	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.615135540121515	[163]	[385,280,301]	9	hSpCas9	negative selection	5972446
35639415	35639438	10	-	27260156	COLO741	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.08738655594035616	[725]	[893,892,834]	-2	hSpCas9	negative selection	5972447
35640715	35640738	10	-	27260156	COLO741	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.06566672129901935	[436]	[623,559,571]	1	hSpCas9	negative selection	5972448
35640683	35640706	10	+	27260156	CAL120	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.1600211416569297	[47]	[66,53,78]	2	hSpCas9	negative selection	6029436
35640706	35640729	10	+	27260156	CAL120	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.11781844352537818	[447]	[600,611,600]	1	hSpCas9	negative selection	6029437
35639794	35639817	10	-	27260156	CAL120	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.20968526445178093	[307]	[427,211,367]	-3	hSpCas9	negative selection	6029438
35640448	35640471	10	+	27260156	CAL120	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.2635229815506974	[163]	[299,135,305]	4	hSpCas9	negative selection	6093697
35639415	35639438	10	-	27260156	CAL120	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.41682659188781496	[725]	[731,672,633]	-6	hSpCas9	negative selection	6093698
35640715	35640738	10	-	27260156	CAL120	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.18970558451775993	[436]	[822,390,271]	-3	hSpCas9	negative selection	6093699
35640683	35640706	10	+	27260156	CADOES1	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.1906767480767382	[47]	[52,197,78,76]	9	hSpCas9	negative selection	6150687
35640706	35640729	10	+	27260156	CADOES1	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.23909182837734072	[447]	[316,195,541,356]	-4	hSpCas9	negative selection	6150688
35639794	35639817	10	-	27260156	CADOES1	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.8295871382777149	[307]	[188,178,133,141]	-9	hSpCas9	negative selection	6150689
35640448	35640471	10	+	27260156	CADOES1	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.11327261394239474	[163]	[154,101,163,142]	-2	hSpCas9	negative selection	6214948
35639415	35639438	10	-	27260156	CADOES1	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.01269349500606054	[725]	[617,842,691,567]	0	hSpCas9	negative selection	6214949
35640715	35640738	10	-	27260156	CADOES1	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.13788280833183653	[436]	[396,357,364,356]	-2	hSpCas9	negative selection	6214950
35640683	35640706	10	+	27260156	EWS502	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.1818199204444655	[47]	[192,105,128,16]	9	hSpCas9	negative selection	6271938
35640706	35640729	10	+	27260156	EWS502	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.11799512308717928	[447]	[419,339,525,470]	-2	hSpCas9	negative selection	6271939
35639794	35639817	10	-	27260156	EWS502	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.4957732824464738	[307]	[244,151,250,281]	-7	hSpCas9	negative selection	6271940
35640448	35640471	10	+	27260156	EWS502	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.10851351230682238	[163]	[216,170,204,149]	1	hSpCas9	negative selection	6336199
35639415	35639438	10	-	27260156	EWS502	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.13540950532143892	[725]	[630,726,835,605]	-2	hSpCas9	negative selection	6336200
35640715	35640738	10	-	27260156	EWS502	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.2974197980609709	[436]	[402,512,603,791]	5	hSpCas9	negative selection	6336201
35640683	35640706	10	+	27260156	EW8	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.4756379224304541	[47]	[40,86,65,18]	8	hSpCas9	negative selection	6393189
35640706	35640729	10	+	27260156	EW8	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.3241798580814857	[447]	[334,259,283,285]	-6	hSpCas9	negative selection	6393190
35639794	35639817	10	-	27260156	EW8	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.42977504842310954	[307]	[285,151,207,101]	-7	hSpCas9	negative selection	6393191
35640448	35640471	10	+	27260156	EW8	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.26476333730403145	[163]	[202,168,124,151]	5	hSpCas9	negative selection	6457450
35639415	35639438	10	-	27260156	EW8	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.26302877701276023	[725]	[523,666,381,409]	-5	hSpCas9	negative selection	6457451
35640715	35640738	10	-	27260156	EW8	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.1403329085819932	[436]	[255,423,301,298]	-3	hSpCas9	negative selection	6457452
35640683	35640706	10	+	27260156	CORL105	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.6048581358372869	[47]	[55,69,110,107]	9	hSpCas9	negative selection	6514440
35640706	35640729	10	+	27260156	CORL105	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.1075494649583607	[447]	[532,519,528,372]	-2	hSpCas9	negative selection	6514441
35639794	35639817	10	-	27260156	CORL105	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.0037707379754093884	[307]	[352,355,475,278]	0	hSpCas9	negative selection	6514442
35640448	35640471	10	+	27260156	CORL105	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.05291639473838283	[163]	[191,245,207,150]	1	hSpCas9	negative selection	6578701
35639415	35639438	10	-	27260156	CORL105	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.12720859013502805	[725]	[660,733,942,796]	-2	hSpCas9	negative selection	6578702
35640715	35640738	10	-	27260156	CORL105	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.19746299084732116	[436]	[429,382,434,534]	-4	hSpCas9	negative selection	6578703
35640683	35640706	10	+	27260156	HS294T	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.1536135937925809	[47]	[77,37,16,25]	9	hSpCas9	negative selection	6635691
35640706	35640729	10	+	27260156	HS294T	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.3973791665389966	[447]	[239,188,169,329]	5	hSpCas9	negative selection	6635692
35639794	35639817	10	-	27260156	HS294T	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.12944453554796387	[307]	[123,93,102,113]	-2	hSpCas9	negative selection	6635693
35640448	35640471	10	+	27260156	HS294T	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.17026445159228443	[163]	[65,52,50,53]	-2	hSpCas9	negative selection	6699952
35639415	35639438	10	-	27260156	HS294T	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.15815099560609713	[725]	[235,178,244,368]	-2	hSpCas9	negative selection	6699953
35640715	35640738	10	-	27260156	HS294T	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.756488574475467	[436]	[180,307,121,589]	8	hSpCas9	negative selection	6699954
35640683	35640706	10	+	27260156	HCC44	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.326344631705088	[47]	[174,53,141,186]	9	hSpCas9	negative selection	6756942
35640706	35640729	10	+	27260156	HCC44	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.14142424817207258	[447]	[637,434,695,511]	2	hSpCas9	negative selection	6756943
35639794	35639817	10	-	27260156	HCC44	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.05294852591056698	[307]	[461,287,393,324]	0	hSpCas9	negative selection	6756944
35640448	35640471	10	+	27260156	HCC44	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.3083242138362223	[163]	[294,146,181,299]	5	hSpCas9	negative selection	6821203
35639415	35639438	10	-	27260156	HCC44	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.081592414330942	[725]	[855,691,1050,922]	1	hSpCas9	negative selection	6821204
35640715	35640738	10	-	27260156	HCC44	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.20899781533205522	[436]	[707,445,709,473]	3	hSpCas9	negative selection	6821205
35640683	35640706	10	+	27260156	G402	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.18819381540036506	[47]	[19,48,167,23]	2	hSpCas9	negative selection	6878193
35640706	35640729	10	+	27260156	G402	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.732830055434498	[447]	[624,83,114,509]	-7	hSpCas9	negative selection	6878194
35639794	35639817	10	-	27260156	G402	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.45786108520699975	[307]	[233,439,162,260]	-5	hSpCas9	negative selection	6878195
35640448	35640471	10	+	27260156	G402	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.22412958696910668	[163]	[453,114,198,192]	3	hSpCas9	negative selection	6942454
35639415	35639438	10	-	27260156	G402	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.44107042446143613	[725]	[377,805,934,466]	-5	hSpCas9	negative selection	6942455
35640715	35640738	10	-	27260156	G402	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.022744310611085616	[436]	[387,618,661,480]	0	hSpCas9	negative selection	6942456
35640683	35640706	10	+	27260156	L33	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.7142546624655863	[47]	[88,24,58,70]	9	hSpCas9	negative selection	6999444
35640706	35640729	10	+	27260156	L33	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.1834207307124381	[447]	[406,238,366,463]	4	hSpCas9	negative selection	6999445
35639794	35639817	10	-	27260156	L33	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.020064591122512243	[307]	[261,134,226,263]	0	hSpCas9	negative selection	6999446
35640448	35640471	10	+	27260156	L33	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.16580137893436597	[163]	[242,48,133,158]	3	hSpCas9	negative selection	7063705
35639415	35639438	10	-	27260156	L33	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.0023788569069866927	[725]	[539,299,490,858]	0	hSpCas9	negative selection	7063706
35640715	35640738	10	-	27260156	L33	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.04673484916766073	[436]	[393,181,345,305]	-1	hSpCas9	negative selection	7063707
35640683	35640706	10	+	27260156	K562	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.9323998930346247	[47]	[66,2,19,3]	-8	hSpCas9	negative selection	7120695
35640706	35640729	10	+	27260156	K562	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.35747154328695524	[447]	[303,1027,480,261]	4	hSpCas9	negative selection	7120696
35639794	35639817	10	-	27260156	K562	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.5780498228263591	[307]	[113,134,211,253]	-6	hSpCas9	negative selection	7120697
35640448	35640471	10	+	27260156	K562	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.16986252806240132	[163]	[143,193,131,181]	2	hSpCas9	negative selection	7184956
35639415	35639438	10	-	27260156	K562	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.04836034291116653	[725]	[557,779,555,600]	0	hSpCas9	negative selection	7184957
35640715	35640738	10	-	27260156	K562	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.3084395100713608	[436]	[177,395,318,941]	4	hSpCas9	negative selection	7184958
35640683	35640706	10	+	27260156	HT29	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.6808703838781214	[47]	[105,117,116,41]	9	hSpCas9	negative selection	7241946
35640706	35640729	10	+	27260156	HT29	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.33425479317523366	[447]	[704,865,633,567]	6	hSpCas9	negative selection	7241947
35639794	35639817	10	-	27260156	HT29	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.4477697280251889	[307]	[379,255,249,222]	-7	hSpCas9	negative selection	7241948
35640448	35640471	10	+	27260156	HT29	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.5390032307568652	[163]	[294,311,379,184]	9	hSpCas9	negative selection	7306207
35639415	35639438	10	-	27260156	HT29	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.08518929568824851	[725]	[915,907,708,804]	-2	hSpCas9	negative selection	7306208
35640715	35640738	10	-	27260156	HT29	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.3334263572572884	[436]	[622,909,553,609]	6	hSpCas9	negative selection	7306209
35640683	35640706	10	+	27260156	MHHES1	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.3045616373902111	[47]	[143,161,110,120]	9	hSpCas9	negative selection	7363197
35640706	35640729	10	+	27260156	MHHES1	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.15874253480178488	[447]	[635,701,504,446]	3	hSpCas9	negative selection	7363198
35639794	35639817	10	-	27260156	MHHES1	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.376011593342495	[307]	[293,281,206,280]	-6	hSpCas9	negative selection	7363199
35640448	35640471	10	+	27260156	MHHES1	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.1585634564677878	[163]	[211,213,121,128]	-3	hSpCas9	negative selection	7427458
35639415	35639438	10	-	27260156	MHHES1	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.011835652659088813	[725]	[894,1125,797,560]	0	hSpCas9	negative selection	7427459
35640715	35640738	10	-	27260156	MHHES1	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.03382411010216692	[436]	[695,550,269,436]	0	hSpCas9	negative selection	7427460
35640683	35640706	10	+	27260156	MEWO	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.3555771081458006	[47]	[99,80,160]	9	hSpCas9	negative selection	7484448
35640706	35640729	10	+	27260156	MEWO	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.15503677266956462	[447]	[623,347,458]	3	hSpCas9	negative selection	7484449
35639794	35639817	10	-	27260156	MEWO	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.029582522292788904	[307]	[308,286,255]	0	hSpCas9	negative selection	7484450
35640448	35640471	10	+	27260156	MEWO	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.483015176350186	[163]	[320,200,141]	8	hSpCas9	negative selection	7548709
35639415	35639438	10	-	27260156	MEWO	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.04184140251884172	[725]	[785,599,617]	-1	hSpCas9	negative selection	7548710
35640715	35640738	10	-	27260156	MEWO	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.44246727831980126	[436]	[629,564,485]	8	hSpCas9	negative selection	7548711
35640683	35640706	10	+	27260156	LNCAPCLONEFGC	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.9848344330799566	[47]	[74,66,128,80]	9	hSpCas9	negative selection	7605699
35640706	35640729	10	+	27260156	LNCAPCLONEFGC	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.2229047039945643	[447]	[331,313,433,325]	-4	hSpCas9	negative selection	7605700
35639794	35639817	10	-	27260156	LNCAPCLONEFGC	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.36931431702100415	[307]	[178,203,233,250]	-5	hSpCas9	negative selection	7605701
35640448	35640471	10	+	27260156	LNCAPCLONEFGC	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.4947872308510739	[163]	[244,135,280,189]	7	hSpCas9	negative selection	7669960
35639415	35639438	10	-	27260156	LNCAPCLONEFGC	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.008056081104117152	[725]	[622,875,576,513]	0	hSpCas9	negative selection	7669961
35640715	35640738	10	-	27260156	LNCAPCLONEFGC	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.0774122792744958	[436]	[408,354,407,333]	-1	hSpCas9	negative selection	7669962
35640683	35640706	10	+	27260156	PANC0327	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.3937801505096141	[47]	[17,44,31,31]	-5	hSpCas9	negative selection	7726950
35640706	35640729	10	+	27260156	PANC0327	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.3305513015942683	[447]	[264,136,495,386]	-5	hSpCas9	negative selection	7726951
35639794	35639817	10	-	27260156	PANC0327	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.184170849353056	[307]	[162,232,269,574]	2	hSpCas9	negative selection	7726952
35640448	35640471	10	+	27260156	PANC0327	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.5042512428633683	[163]	[135,147,136,406]	7	hSpCas9	negative selection	7791211
35639415	35639438	10	-	27260156	PANC0327	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.2118836056579555	[725]	[798,710,563,921]	3	hSpCas9	negative selection	7791212
35640715	35640738	10	-	27260156	PANC0327	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.5041364449716828	[436]	[198,131,375,399]	-6	hSpCas9	negative selection	7791213
35640683	35640706	10	+	27260156	NCIH2009	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.9520360673552779	[47]	[134,76,178]	9	hSpCas9	negative selection	7848201
35640706	35640729	10	+	27260156	NCIH2009	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.08143696055723273	[447]	[853,639,529]	1	hSpCas9	negative selection	7848202
35639794	35639817	10	-	27260156	NCIH2009	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.15999222096034893	[307]	[404,259,495]	-2	hSpCas9	negative selection	7848203
35640448	35640471	10	+	27260156	NCIH2009	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.20978063538149927	[163]	[330,186,290]	3	hSpCas9	negative selection	7912462
35639415	35639438	10	-	27260156	NCIH2009	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.08076132536789993	[725]	[1172,627,1122]	-1	hSpCas9	negative selection	7912463
35640715	35640738	10	-	27260156	NCIH2009	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.41063745664704165	[436]	[862,677,904]	5	hSpCas9	negative selection	7912464
35640683	35640706	10	+	27260156	NCIH1373	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.9706140896627504	[47]	[42,155,152,12]	8	hSpCas9	negative selection	7969452
35640706	35640729	10	+	27260156	NCIH1373	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.2180122621817404	[447]	[785,245,409,92]	-2	hSpCas9	negative selection	7969453
35639794	35639817	10	-	27260156	NCIH1373	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.023632980708297557	[307]	[473,223,210,141]	0	hSpCas9	negative selection	7969454
35640448	35640471	10	+	27260156	NCIH1373	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.05232755072561934	[163]	[49,29,201,114]	0	hSpCas9	negative selection	8033713
35639415	35639438	10	-	27260156	NCIH1373	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.008678176723141195	[725]	[861,662,821,250]	0	hSpCas9	negative selection	8033714
35640715	35640738	10	-	27260156	NCIH1373	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.6274819057985466	[436]	[484,215,276,85]	-6	hSpCas9	negative selection	8033715
35640683	35640706	10	+	27260156	PATU8902	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.9033489898201883	[47]	[70,124,136,168]	8	hSpCas9	negative selection	8090703
35640706	35640729	10	+	27260156	PATU8902	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.1778285497017491	[447]	[464,546,939,820]	1	hSpCas9	negative selection	8090704
35639794	35639817	10	-	27260156	PATU8902	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.35554020732555985	[307]	[430,620,447,741]	3	hSpCas9	negative selection	8090705
35640448	35640471	10	+	27260156	PATU8902	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.3025672359725906	[163]	[328,260,213,344]	3	hSpCas9	negative selection	8154964
35639415	35639438	10	-	27260156	PATU8902	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	0.35308602330893757	[725]	[1083,1161,960,2137]	3	hSpCas9	negative selection	8154965
35640715	35640738	10	-	27260156	PATU8902	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.28802330205628607	[436]	[632,840,840,611]	3	hSpCas9	negative selection	8154966
35640683	35640706	10	+	27260156	PANC1	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.8218962156028269	[47]	[87,50,129,24]	9	hSpCas9	negative selection	8211954
35640706	35640729	10	+	27260156	PANC1	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.3842047961899196	[447]	[484,539,379,587]	6	hSpCas9	negative selection	8211955
35639794	35639817	10	-	27260156	PANC1	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.6858771119582711	[307]	[436,262,593,376]	9	hSpCas9	negative selection	8211956
35640448	35640471	10	+	27260156	PANC1	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.21176192952593076	[163]	[108,235,89,79]	-3	hSpCas9	negative selection	8276215
35639415	35639438	10	-	27260156	PANC1	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.08648803383085835	[725]	[657,696,569,456]	-1	hSpCas9	negative selection	8276216
35640715	35640738	10	-	27260156	PANC1	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.0466534758949193	[436]	[345,483,415,328]	0	hSpCas9	negative selection	8276217
35640683	35640706	10	+	27260156	PANC0813	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.8890191622052273	[47]	[160,70,74,114]	9	hSpCas9	negative selection	8333205
35640706	35640729	10	+	27260156	PANC0813	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.5612743777977767	[447]	[1008,816,728,581]	8	hSpCas9	negative selection	8333206
35639794	35639817	10	-	27260156	PANC0813	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.053133813438800415	[307]	[380,295,384,435]	0	hSpCas9	negative selection	8333207
35640448	35640471	10	+	27260156	PANC0813	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.33277439771937267	[163]	[276,168,241,282]	5	hSpCas9	negative selection	8397466
35639415	35639438	10	-	27260156	PANC0813	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.08867703488474987	[725]	[770,1003,614,811]	-1	hSpCas9	negative selection	8397467
35640715	35640738	10	-	27260156	PANC0813	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.1267165798223579	[436]	[677,567,527,481]	2	hSpCas9	negative selection	8397468
35640683	35640706	10	+	27260156	RDES	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.5838327693471013	[47]	[47,46,129,122]	8	hSpCas9	negative selection	8454456
35640706	35640729	10	+	27260156	RDES	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.022147681194201553	[447]	[399,513,558,652]	0	hSpCas9	negative selection	8454457
35639794	35639817	10	-	27260156	RDES	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.1632378097006073	[307]	[228,305,306,454]	-3	hSpCas9	negative selection	8454458
35640448	35640471	10	+	27260156	RDES	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.06720159137265447	[163]	[155,165,219,265]	1	hSpCas9	negative selection	8518717
35639415	35639438	10	-	27260156	RDES	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.18073311188014463	[725]	[529,713,827,933]	-3	hSpCas9	negative selection	8518718
35640715	35640738	10	-	27260156	RDES	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.046021381655726626	[436]	[529,388,483,533]	0	hSpCas9	negative selection	8518719
35640683	35640706	10	+	27260156	PC3	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.32597454594293485	[47]	[54,5,43,128]	7	hSpCas9	negative selection	8575707
35640706	35640729	10	+	27260156	PC3	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.798893322037428	[447]	[130,231,482,306]	-9	hSpCas9	negative selection	8575708
35639794	35639817	10	-	27260156	PC3	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-1.0269384706323423	[307]	[120,96,292,144]	-9	hSpCas9	negative selection	8575709
35640448	35640471	10	+	27260156	PC3	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.5336372977261847	[163]	[83,137,173,75]	-8	hSpCas9	negative selection	8639968
35639415	35639438	10	-	27260156	PC3	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.3541844713655199	[725]	[378,550,883,599]	-7	hSpCas9	negative selection	8639969
35640715	35640738	10	-	27260156	PC3	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.39332027019128596	[436]	[197,381,635,249]	-7	hSpCas9	negative selection	8639970
35640683	35640706	10	+	27260156	PATU8988T	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.3825699816848176	[47]	[34,12,73,119]	6	hSpCas9	negative selection	8696958
35640706	35640729	10	+	27260156	PATU8988T	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.4195236559077035	[447]	[227,270,344,455]	-6	hSpCas9	negative selection	8696959
35639794	35639817	10	-	27260156	PATU8988T	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.1260712868190189	[307]	[238,380,99,392]	-2	hSpCas9	negative selection	8696960
35640448	35640471	10	+	27260156	PATU8988T	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.2838892318479651	[163]	[310,185,68,207]	5	hSpCas9	negative selection	8761219
35639415	35639438	10	-	27260156	PATU8988T	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.3461770688498309	[725]	[407,608,783,395]	-5	hSpCas9	negative selection	8761220
35640715	35640738	10	-	27260156	PATU8988T	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.034308909211854824	[436]	[533,677,269,258]	0	hSpCas9	negative selection	8761221
35640683	35640706	10	+	27260156	T47D	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.45001792130984963	[47]	[92,56,64,92]	8	hSpCas9	negative selection	8818209
35640706	35640729	10	+	27260156	T47D	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.13566548670195594	[447]	[361,426,581,532]	-3	hSpCas9	negative selection	8818210
35639794	35639817	10	-	27260156	T47D	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.5389974528729473	[307]	[192,250,282,259]	-8	hSpCas9	negative selection	8818211
35640448	35640471	10	+	27260156	T47D	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.19342659113963157	[163]	[161,213,298,196]	4	hSpCas9	negative selection	8882470
35639415	35639438	10	-	27260156	T47D	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.07404599872737494	[725]	[865,733,728,894]	-2	hSpCas9	negative selection	8882471
35640715	35640738	10	-	27260156	T47D	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.06725485000885627	[436]	[516,430,512,486]	-1	hSpCas9	negative selection	8882472
35640683	35640706	10	+	27260156	SU8686	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.2525271373434266	[47]	[92,30,169,184]	9	hSpCas9	negative selection	8939460
35640706	35640729	10	+	27260156	SU8686	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.03986810429001425	[447]	[411,357,505,468]	0	hSpCas9	negative selection	8939461
35639794	35639817	10	-	27260156	SU8686	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.21473611963294986	[307]	[384,313,324,398]	3	hSpCas9	negative selection	8939462
35640448	35640471	10	+	27260156	SU8686	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.06930470292031687	[163]	[171,100,224,197]	1	hSpCas9	negative selection	9003721
35639415	35639438	10	-	27260156	SU8686	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.17660341925498046	[725]	[560,659,671,659]	-3	hSpCas9	negative selection	9003722
35640715	35640738	10	-	27260156	SU8686	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.03529784477687163	[436]	[342,329,448,619]	0	hSpCas9	negative selection	9003723
35640683	35640706	10	+	27260156	SKES1	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	1.0133524977721682	[47]	[122,123,78,69]	9	hSpCas9	negative selection	9060711
35640706	35640729	10	+	27260156	SKES1	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.27362360552390064	[447]	[468,402,468,173]	-6	hSpCas9	negative selection	9060712
35639794	35639817	10	-	27260156	SKES1	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.6954524809224247	[307]	[198,154,212,186]	-9	hSpCas9	negative selection	9060713
35640448	35640471	10	+	27260156	SKES1	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.09974952105307833	[163]	[152,266,152,138]	2	hSpCas9	negative selection	9124972
35639415	35639438	10	-	27260156	SKES1	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.050428119418428285	[725]	[804,805,759,472]	-1	hSpCas9	negative selection	9124973
35640715	35640738	10	-	27260156	SKES1	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.05526653732748567	[436]	[480,397,461,461]	1	hSpCas9	negative selection	9124974
35640683	35640706	10	+	27260156	TOV112D	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	-0.058374802642993995	[47]	[49,16,73,36]	-1	hSpCas9	negative selection	9181962
35640706	35640729	10	+	27260156	TOV112D	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	0.2987001120875673	[447]	[438,802,500,516]	5	hSpCas9	negative selection	9181963
35639794	35639817	10	-	27260156	TOV112D	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	0.15057910397474944	[307]	[350,424,157,452]	3	hSpCas9	negative selection	9181964
35640448	35640471	10	+	27260156	TOV112D	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	0.5162076430316611	[163]	[307,172,279,170]	8	hSpCas9	negative selection	9246223
35639415	35639438	10	-	27260156	TOV112D	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.05395456426399137	[725]	[681,945,731,504]	-1	hSpCas9	negative selection	9246224
35640715	35640738	10	-	27260156	TOV112D	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.29240808263925366	[436]	[645,675,477,390]	5	hSpCas9	negative selection	9246225
35640683	35640706	10	+	27260156	TC71	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.9523791429310688	[47]	[83,149,82,80]	9	hSpCas9	negative selection	9303213
35640706	35640729	10	+	27260156	TC71	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.20406192897360853	[447]	[410,368,368,526]	-5	hSpCas9	negative selection	9303214
35639794	35639817	10	-	27260156	TC71	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.4601989231780914	[307]	[189,254,253,262]	-8	hSpCas9	negative selection	9303215
35640448	35640471	10	+	27260156	TC71	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.26378278849794246	[163]	[115,178,148,141]	-6	hSpCas9	negative selection	9367474
35639415	35639438	10	-	27260156	TC71	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.23962728432764935	[725]	[574,733,639,691]	-6	hSpCas9	negative selection	9367475
35640715	35640738	10	-	27260156	TC71	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	0.1111035825934014	[436]	[530,498,524,464]	3	hSpCas9	negative selection	9367476
35640683	35640706	10	+	27260156	TC32	viability	GTAGAGCGGGTGGCGCTCGCTGG	FZD8	ENSG00000177283	0.05315240140236188	[47]	[20,9,68,109]	1	hSpCas9	negative selection	9424464
35640706	35640729	10	+	27260156	TC32	viability	ACACGCTCACCATAGGCGCGCGG	FZD8	ENSG00000177283	-0.6872361720071309	[447]	[252,122,376,357]	-8	hSpCas9	negative selection	9424465
35639794	35639817	10	-	27260156	TC32	viability	GCTCTACACCGTGCCCGCCGCGG	FZD8	ENSG00000177283	-0.6123399974968025	[307]	[106,120,273,302]	-8	hSpCas9	negative selection	9424466
35640448	35640471	10	+	27260156	TC32	viability	GGTAGCCCACCGACACGAAGAGG	FZD8	ENSG00000177283	-0.1512328572703685	[163]	[150,78,219,131]	-3	hSpCas9	negative selection	9488725
35639415	35639438	10	-	27260156	TC32	viability	CTCTACAGCGACGTCAGCACTGG	FZD8	ENSG00000177283	-0.293261522085036	[725]	[503,458,859,460]	-5	hSpCas9	negative selection	9488726
35640715	35640738	10	-	27260156	TC32	viability	GTGCCAGTGCCGCGCGCCTATGG	FZD8	ENSG00000177283	-0.21697270528747148	[436]	[338,259,411,432]	-4	hSpCas9	negative selection	9488727
35640463	35640486	10	+	27869803	HPAFII	viability after 27 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.5811144676105454	[632]	[342,121,NaN]	-4	hSpCas9	negative selection	9537840
35640497	35640520	10	-	27869803	HPAFII	viability after 27 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.6494786004529682	[335]	[359,207,NaN]	5	hSpCas9	negative selection	9537841
35640520	35640543	10	-	27869803	HPAFII	viability after 27 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.3520121421567417	[660]	[358,513,NaN]	3	hSpCas9	negative selection	9537842
35640658	35640681	10	+	27869803	HPAFII	viability after 27 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.4049991330883511	[609]	[398,445,NaN]	3	hSpCas9	negative selection	9537843
35641287	35641310	10	+	27869803	HPAFII	viability after 27 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.27616312482800387	[624]	[296,481,NaN]	2	hSpCas9	negative selection	9537844
35640463	35640486	10	+	27869803	HPAFII	viability after 15 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.11505809342929774	[632]	[859,483,NaN]	-1	hSpCas9	negative selection	9620289
35640497	35640520	10	-	27869803	HPAFII	viability after 15 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.07572886805989248	[335]	[596,245,NaN]	0	hSpCas9	negative selection	9620290
35640520	35640543	10	-	27869803	HPAFII	viability after 15 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.48624103509389016	[660]	[819,1103,NaN]	5	hSpCas9	negative selection	9620291
35640658	35640681	10	+	27869803	HPAFII	viability after 15 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.6727109277531063	[609]	[1176,962,NaN]	7	hSpCas9	negative selection	9620292
35641287	35641310	10	+	27869803	HPAFII	viability after 15 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.12570102826543472	[624]	[804,687,NaN]	1	hSpCas9	negative selection	9620293
35640463	35640486	10	+	27869803	ASPC1	viability after 36 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.11001269702837457	[1591]	[698,561,342]	-1	hSpCas9	negative selection	9702738
35640497	35640520	10	-	27869803	ASPC1	viability after 36 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	-0.2358847838108849	[951]	[406,180,271]	-2	hSpCas9	negative selection	9702739
35640520	35640543	10	-	27869803	ASPC1	viability after 36 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.46708466745946575	[1779]	[1106,1063,512]	5	hSpCas9	negative selection	9702740
35640658	35640681	10	+	27869803	ASPC1	viability after 36 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.7872113078480523	[1653]	[1161,665,1131]	7	hSpCas9	negative selection	9702741
35641287	35641310	10	+	27869803	ASPC1	viability after 36 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.008826681037858108	[1681]	[740,896,235]	0	hSpCas9	negative selection	9702742
35640463	35640486	10	+	27869803	PATU8988S	viability after 35 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.10516471539810124	[1191]	[463,568,NaN]	1	hSpCas9	negative selection	9785187
35640497	35640520	10	-	27869803	PATU8988S	viability after 35 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.15647445219660627	[704]	[301,330,NaN]	1	hSpCas9	negative selection	9785188
35640520	35640543	10	-	27869803	PATU8988S	viability after 35 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.08456274003151076	[1606]	[554,665,NaN]	-1	hSpCas9	negative selection	9785189
35640658	35640681	10	+	27869803	PATU8988S	viability after 35 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.06079258820952416	[1527]	[592,690,NaN]	0	hSpCas9	negative selection	9785190
35641287	35641310	10	+	27869803	PATU8988S	viability after 35 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.8374448685433415	[1377]	[1079,902,NaN]	8	hSpCas9	negative selection	9785191
35640463	35640486	10	+	27869803	PATU8988S	viability after 31 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	0.3237475968877346	[1191]	[388,856,NaN]	4	hSpCas9	negative selection	9867636
35640497	35640520	10	-	27869803	PATU8988S	viability after 31 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.31008237849236864	[704]	[344,352,NaN]	4	hSpCas9	negative selection	9867637
35640520	35640543	10	-	27869803	PATU8988S	viability after 31 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	-0.20728411773541144	[1606]	[470,661,NaN]	-2	hSpCas9	negative selection	9867638
35640658	35640681	10	+	27869803	PATU8988S	viability after 31 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.08457556992564585	[1527]	[576,733,NaN]	1	hSpCas9	negative selection	9867639
35641287	35641310	10	+	27869803	PATU8988S	viability after 31 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	0.6904030120051752	[1377]	[964,786,NaN]	7	hSpCas9	negative selection	9867640
35640463	35640486	10	+	27869803	HPAFII	viability after 35 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.6673433704734503	[632]	[348,35,NaN]	-4	hSpCas9	negative selection	9950085
35640497	35640520	10	-	27869803	HPAFII	viability after 35 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.50433943510739	[335]	[213,271,NaN]	3	hSpCas9	negative selection	9950086
35640520	35640543	10	-	27869803	HPAFII	viability after 35 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.32849273020526537	[660]	[335,514,NaN]	2	hSpCas9	negative selection	9950087
35640658	35640681	10	+	27869803	HPAFII	viability after 35 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.9656547986971515	[609]	[429,797,NaN]	6	hSpCas9	negative selection	9950088
35641287	35641310	10	+	27869803	HPAFII	viability after 35 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.1409950902059256	[624]	[293,278,NaN]	-1	hSpCas9	negative selection	9950089
35640463	35640486	10	+	27869803	HPAFII	viability after 31 days	CGAAGAGGTAGCAGGCCGAGAGG	FZD8	ENSG00000177283	-0.6931587229518987	[632]	[313,116,NaN]	-4	hSpCas9	negative selection	10032534
35640497	35640520	10	-	27869803	HPAFII	viability after 31 days	AGCGCTTCAAGTACCCGGAGCGG	FZD8	ENSG00000177283	0.5786670794729474	[335]	[261,302,NaN]	4	hSpCas9	negative selection	10032535
35640520	35640543	10	-	27869803	HPAFII	viability after 31 days	CTCCACCTTCCTTATCGACATGG	FZD8	ENSG00000177283	0.20462124255914493	[660]	[270,597,NaN]	1	hSpCas9	negative selection	10032536
35640658	35640681	10	+	27869803	HPAFII	viability after 31 days	CGATCTGGCCTGTCTTGACGCGG	FZD8	ENSG00000177283	0.9560090063752591	[609]	[409,940,NaN]	7	hSpCas9	negative selection	10032537
35641287	35641310	10	+	27869803	HPAFII	viability after 31 days	TAGCCGATGCCCTTACACAGCGG	FZD8	ENSG00000177283	-0.2966694310572009	[624]	[219,356,NaN]	-2	hSpCas9	negative selection	10032538
35640402	35640425	10	-	28162770	P31FUJ	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.36045643786186893	[288]	[435]	4	hSpCas9	negative selection	10159757
35640230	35640253	10	+	28162770	P31FUJ	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	1.0437154307830374	[212]	[515]	9	hSpCas9	negative selection	10159758
35640050	35640073	10	+	28162770	P31FUJ	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	0.519270282142036	[75]	[127]	6	hSpCas9	negative selection	10159759
35641367	35641390	10	+	28162770	P31FUJ	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.1954347926193245	[135]	[182]	2	hSpCas9	negative selection	10159760
35641351	35641374	10	-	28162770	P31FUJ	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	1.1743731770914947	[68]	[182]	9	hSpCas9	negative selection	10159761
35640888	35640911	10	-	28162770	P31FUJ	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.39484669540832784	[221]	[342]	4	hSpCas9	negative selection	10159762
35640584	35640607	10	+	28162770	P31FUJ	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.731246812989469	[385]	[752]	8	hSpCas9	negative selection	10159763
35640533	35640556	10	+	28162770	P31FUJ	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.5177463620247523	[295]	[497]	6	hSpCas9	negative selection	10159764
35640433	35640456	10	-	28162770	P31FUJ	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.7000835997270846	[230]	[440]	7	hSpCas9	negative selection	10159765
35640283	35640306	10	-	28162770	P31FUJ	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-1.1252965789463933	[348]	[187]	-7	hSpCas9	negative selection	10159766
35640402	35640425	10	-	28162770	TF1	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	NaN	[NaN]	[237]	1	hSpCas9	negative selection	10329123
35640230	35640253	10	+	28162770	TF1	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10329124
35640050	35640073	10	+	28162770	TF1	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10329125
35641367	35641390	10	+	28162770	TF1	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10329126
35641351	35641374	10	-	28162770	TF1	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	NaN	[NaN]	[188]	1	hSpCas9	negative selection	10329127
35640888	35640911	10	-	28162770	TF1	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	NaN	[NaN]	[307]	1	hSpCas9	negative selection	10329128
35640584	35640607	10	+	28162770	TF1	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	NaN	[NaN]	[187]	1	hSpCas9	negative selection	10329129
35640533	35640556	10	+	28162770	TF1	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10329130
35640433	35640456	10	-	28162770	TF1	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10329131
35640283	35640306	10	-	28162770	TF1	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10329132
35640402	35640425	10	-	28162770	SKM1	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.07611868795878085	[109]	[204]	0	hSpCas9	negative selection	10498489
35640230	35640253	10	+	28162770	SKM1	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	-1.149166441275515	[68]	[54]	-7	hSpCas9	negative selection	10498490
35640050	35640073	10	+	28162770	SKM1	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	0.11290327375610976	[33]	[64]	1	hSpCas9	negative selection	10498491
35641367	35641390	10	+	28162770	SKM1	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.12141477361162706	[51]	[99]	1	hSpCas9	negative selection	10498492
35641351	35641374	10	-	28162770	SKM1	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.2711077063694761	[29]	[63]	2	hSpCas9	negative selection	10498493
35640888	35640911	10	-	28162770	SKM1	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.5203904994250723	[55]	[141]	5	hSpCas9	negative selection	10498494
35640584	35640607	10	+	28162770	SKM1	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.4382340744591149	[85]	[205]	4	hSpCas9	negative selection	10498495
35640533	35640556	10	+	28162770	SKM1	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.3786956522151235	[66]	[153]	3	hSpCas9	negative selection	10498496
35640433	35640456	10	-	28162770	SKM1	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.33974937197460653	[58]	[131]	3	hSpCas9	negative selection	10498497
35640283	35640306	10	-	28162770	SKM1	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	0.13314406619373403	[48]	[94]	1	hSpCas9	negative selection	10498498
35640402	35640425	10	-	28162770	SKM1	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.07611868795878085	[109]	[204]	0	hSpCas9	negative selection	10667855
35640230	35640253	10	+	28162770	SKM1	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	-1.149166441275515	[68]	[54]	-7	hSpCas9	negative selection	10667856
35640050	35640073	10	+	28162770	SKM1	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	0.11290327375610976	[33]	[64]	1	hSpCas9	negative selection	10667857
35641367	35641390	10	+	28162770	SKM1	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.12141477361162706	[51]	[99]	1	hSpCas9	negative selection	10667858
35641351	35641374	10	-	28162770	SKM1	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.2711077063694761	[29]	[63]	2	hSpCas9	negative selection	10667859
35640888	35640911	10	-	28162770	SKM1	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.5203904994250723	[55]	[141]	5	hSpCas9	negative selection	10667860
35640584	35640607	10	+	28162770	SKM1	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.4382340744591149	[85]	[205]	4	hSpCas9	negative selection	10667861
35640533	35640556	10	+	28162770	SKM1	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.3786956522151235	[66]	[153]	3	hSpCas9	negative selection	10667862
35640433	35640456	10	-	28162770	SKM1	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.33974937197460653	[58]	[131]	3	hSpCas9	negative selection	10667863
35640283	35640306	10	-	28162770	SKM1	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	0.13314406619373403	[48]	[94]	1	hSpCas9	negative selection	10667864
35640402	35640425	10	-	28162770	PL21	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.011105790099303126	[341]	[149]	0	hSpCas9	negative selection	10837221
35640230	35640253	10	+	28162770	PL21	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.6867303747931979	[176]	[123]	6	hSpCas9	negative selection	10837222
35640050	35640073	10	+	28162770	PL21	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	-0.368703220868559	[88]	[29]	-3	hSpCas9	negative selection	10837223
35641367	35641390	10	+	28162770	PL21	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	-0.2547623456674632	[158]	[57]	-2	hSpCas9	negative selection	10837224
35641351	35641374	10	-	28162770	PL21	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	-1.64785729206563	[71]	[9]	-8	hSpCas9	negative selection	10837225
35640888	35640911	10	-	28162770	PL21	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.8337120594350981	[213]	[165]	7	hSpCas9	negative selection	10837226
35640584	35640607	10	+	28162770	PL21	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	-0.33037510220945976	[337]	[116]	-2	hSpCas9	negative selection	10837227
35640533	35640556	10	+	28162770	PL21	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	-1.1019799993178618	[216]	[43]	-6	hSpCas9	negative selection	10837228
35640433	35640456	10	-	28162770	PL21	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.6382607268812053	[185]	[125]	5	hSpCas9	negative selection	10837229
35640283	35640306	10	-	28162770	PL21	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-0.0005577357478085965	[153]	[66]	0	hSpCas9	negative selection	10837230
35640402	35640425	10	-	28162770	P31FUJ	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.36045643786186893	[288]	[435]	4	hSpCas9	negative selection	11006587
35640230	35640253	10	+	28162770	P31FUJ	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	1.0437154307830374	[212]	[515]	9	hSpCas9	negative selection	11006588
35640050	35640073	10	+	28162770	P31FUJ	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	0.519270282142036	[75]	[127]	6	hSpCas9	negative selection	11006589
35641367	35641390	10	+	28162770	P31FUJ	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.1954347926193245	[135]	[182]	2	hSpCas9	negative selection	11006590
35641351	35641374	10	-	28162770	P31FUJ	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	1.1743731770914947	[68]	[182]	9	hSpCas9	negative selection	11006591
35640888	35640911	10	-	28162770	P31FUJ	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.39484669540832784	[221]	[342]	4	hSpCas9	negative selection	11006592
35640584	35640607	10	+	28162770	P31FUJ	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.731246812989469	[385]	[752]	8	hSpCas9	negative selection	11006593
35640533	35640556	10	+	28162770	P31FUJ	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.5177463620247523	[295]	[497]	6	hSpCas9	negative selection	11006594
35640433	35640456	10	-	28162770	P31FUJ	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.7000835997270846	[230]	[440]	7	hSpCas9	negative selection	11006595
35640283	35640306	10	-	28162770	P31FUJ	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-1.1252965789463933	[348]	[187]	-7	hSpCas9	negative selection	11006596
35640402	35640425	10	-	28162770	OCIAML5	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	-0.4261407554424169	[197]	[265]	-3	hSpCas9	negative selection	11175953
35640230	35640253	10	+	28162770	OCIAML5	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.7626432732512112	[127]	[391]	6	hSpCas9	negative selection	11175954
35640050	35640073	10	+	28162770	OCIAML5	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	-0.10312833503171503	[71]	[120]	0	hSpCas9	negative selection	11175955
35641367	35641390	10	+	28162770	OCIAML5	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	1.03845495233751	[64]	[240]	8	hSpCas9	negative selection	11175956
35641351	35641374	10	-	28162770	OCIAML5	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	1.6714953851930159	[35]	[206]	9	hSpCas9	negative selection	11175957
35640888	35640911	10	-	28162770	OCIAML5	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.5468512630515697	[134]	[355]	5	hSpCas9	negative selection	11175958
35640584	35640607	10	+	28162770	OCIAML5	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	-0.578181644961424	[286]	[346]	-4	hSpCas9	negative selection	11175959
35640533	35640556	10	+	28162770	OCIAML5	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.4975178669262308	[92]	[236]	4	hSpCas9	negative selection	11175960
35640433	35640456	10	-	28162770	OCIAML5	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	-0.11730524762452096	[130]	[217]	-1	hSpCas9	negative selection	11175961
35640283	35640306	10	-	28162770	OCIAML5	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-1.7707664687621487	[137]	[72]	-7	hSpCas9	negative selection	11175962
35640402	35640425	10	-	28162770	EOL1	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	-0.05098033025933013	[642]	[326]	0	hSpCas9	negative selection	11345319
35640230	35640253	10	+	28162770	EOL1	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.051036300580289407	[250]	[136]	0	hSpCas9	negative selection	11345320
35640050	35640073	10	+	28162770	EOL1	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	0.5868523608248556	[114]	[90]	5	hSpCas9	negative selection	11345321
35641367	35641390	10	+	28162770	EOL1	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.6453241276374104	[232]	[191]	6	hSpCas9	negative selection	11345322
35641351	35641374	10	-	28162770	EOL1	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.8279745118754818	[138]	[129]	7	hSpCas9	negative selection	11345323
35640888	35640911	10	-	28162770	EOL1	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	1.4894167017844608	[481]	[712]	9	hSpCas9	negative selection	11345324
35640584	35640607	10	+	28162770	EOL1	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	-0.7275289250091586	[395]	[125]	-5	hSpCas9	negative selection	11345325
35640533	35640556	10	+	28162770	EOL1	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	-0.10787370612184284	[314]	[153]	-1	hSpCas9	negative selection	11345326
35640433	35640456	10	-	28162770	EOL1	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.500866177882439	[278]	[207]	4	hSpCas9	negative selection	11345327
35640283	35640306	10	-	28162770	EOL1	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-1.0655367595643825	[289]	[72]	-6	hSpCas9	negative selection	11345328
35640402	35640425	10	-	28162770	MOLM13	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.8265356989730244	[449]	[576]	6	hSpCas9	negative selection	11514685
35640230	35640253	10	+	28162770	MOLM13	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	-0.49088795572890825	[275]	[141]	-3	hSpCas9	negative selection	11514686
35640050	35640073	10	+	28162770	MOLM13	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	1.2026507047840547	[130]	[217]	8	hSpCas9	negative selection	11514687
35641367	35641390	10	+	28162770	MOLM13	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.31732970496919755	[221]	[199]	2	hSpCas9	negative selection	11514688
35641351	35641374	10	-	28162770	MOLM13	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.5180751387127955	[112]	[116]	4	hSpCas9	negative selection	11514689
35640888	35640911	10	-	28162770	MOLM13	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.8903443523859057	[290]	[389]	6	hSpCas9	negative selection	11514690
35640584	35640607	10	+	28162770	MOLM13	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.3484891296450735	[490]	[451]	2	hSpCas9	negative selection	11514691
35640533	35640556	10	+	28162770	MOLM13	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	-0.3173717696624085	[242]	[140]	-2	hSpCas9	negative selection	11514692
35640433	35640456	10	-	28162770	MOLM13	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.5948622378023442	[249]	[272]	4	hSpCas9	negative selection	11514693
35640283	35640306	10	-	28162770	MOLM13	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-2.6564387534576226	[217]	[24]	-8	hSpCas9	negative selection	11514694
35640402	35640425	10	-	28162770	HEL	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.18292264850915307	[468]	[340]	1	hSpCas9	negative selection	11684051
35640230	35640253	10	+	28162770	HEL	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	-0.1508102905322166	[259]	[149]	-1	hSpCas9	negative selection	11684052
35640050	35640073	10	+	28162770	HEL	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	1.1367276726740227	[119]	[168]	8	hSpCas9	negative selection	11684053
35641367	35641390	10	+	28162770	HEL	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	1.4191954771837305	[208]	[357]	9	hSpCas9	negative selection	11684054
35641351	35641374	10	-	28162770	HEL	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.8975527310291823	[87]	[104]	7	hSpCas9	negative selection	11684055
35640888	35640911	10	-	28162770	HEL	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	1.7218453769928639	[274]	[580]	9	hSpCas9	negative selection	11684056
35640584	35640607	10	+	28162770	HEL	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.33424911143779934	[373]	[301]	2	hSpCas9	negative selection	11684057
35640533	35640556	10	+	28162770	HEL	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.05238307250898225	[267]	[177]	0	hSpCas9	negative selection	11684058
35640433	35640456	10	-	28162770	HEL	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	-0.22044447836926923	[190]	[104]	-1	hSpCas9	negative selection	11684059
35640283	35640306	10	-	28162770	HEL	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-3.0068766270630527	[250]	[19]	-8	hSpCas9	negative selection	11684060
35640402	35640425	10	-	28162770	MV411	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.49958847225525793	[376]	[448]	4	hSpCas9	negative selection	11853417
35640230	35640253	10	+	28162770	MV411	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	-0.02897588485221817	[194]	[160]	0	hSpCas9	negative selection	11853418
35640050	35640073	10	+	28162770	MV411	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	0.7530775988425258	[80]	[114]	6	hSpCas9	negative selection	11853419
35641367	35641390	10	+	28162770	MV411	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.362149209659468	[144]	[156]	3	hSpCas9	negative selection	11853420
35641351	35641374	10	-	28162770	MV411	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	1.497664180315949	[65]	[156]	9	hSpCas9	negative selection	11853421
35640888	35640911	10	-	28162770	MV411	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.7426786677799727	[292]	[412]	6	hSpCas9	negative selection	11853422
35640584	35640607	10	+	28162770	MV411	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	-0.04880390044093752	[333]	[271]	0	hSpCas9	negative selection	11853423
35640533	35640556	10	+	28162770	MV411	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.4895718759806792	[196]	[232]	4	hSpCas9	negative selection	11853424
35640433	35640456	10	-	28162770	MV411	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	-0.5391588111080314	[206]	[119]	-4	hSpCas9	negative selection	11853425
35640283	35640306	10	-	28162770	MV411	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-0.7993566606961661	[187]	[90]	-5	hSpCas9	negative selection	11853426
35640402	35640425	10	-	28162770	MONOMAC1	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	-0.12165503521741616	[260]	[274]	-1	hSpCas9	negative selection	12022783
35640230	35640253	10	+	28162770	MONOMAC1	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.557850655103915	[111]	[188]	5	hSpCas9	negative selection	12022784
35640050	35640073	10	+	28162770	MONOMAC1	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	-0.44758030871015086	[68]	[57]	-4	hSpCas9	negative selection	12022785
35641367	35641390	10	+	28162770	MONOMAC1	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	-0.004391769117157718	[97]	[111]	0	hSpCas9	negative selection	12022786
35641351	35641374	10	-	28162770	MONOMAC1	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.7332541811290418	[52]	[100]	7	hSpCas9	negative selection	12022787
35640888	35640911	10	-	28162770	MONOMAC1	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.23394219608831165	[134]	[181]	2	hSpCas9	negative selection	12022788
35640584	35640607	10	+	28162770	MONOMAC1	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.9889135783088341	[188]	[429]	8	hSpCas9	negative selection	12022789
35640533	35640556	10	+	28162770	MONOMAC1	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	-0.581047450717773	[183]	[140]	-5	hSpCas9	negative selection	12022790
35640433	35640456	10	-	28162770	MONOMAC1	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.433440312913971	[103]	[160]	4	hSpCas9	negative selection	12022791
35640283	35640306	10	-	28162770	MONOMAC1	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-0.08851239028138483	[127]	[137]	-1	hSpCas9	negative selection	12022792
35640402	35640425	10	-	28162770	OCIAML2	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.7829112946649507	[53]	[514]	7	hSpCas9	negative selection	12192149
35640230	35640253	10	+	28162770	OCIAML2	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.8751450115995689	[29]	[304]	8	hSpCas9	negative selection	12192150
35640050	35640073	10	+	28162770	OCIAML2	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	-0.044365070540063334	[15]	[85]	0	hSpCas9	negative selection	12192151
35641367	35641390	10	+	28162770	OCIAML2	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	0.010496864494455298	[35]	[200]	0	hSpCas9	negative selection	12192152
35641351	35641374	10	-	28162770	OCIAML2	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.7703782742616337	[10]	[103]	7	hSpCas9	negative selection	12192153
35640888	35640911	10	-	28162770	OCIAML2	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	0.5178745359200093	[62]	[499]	5	hSpCas9	negative selection	12192154
35640584	35640607	10	+	28162770	OCIAML2	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.5008010225610677	[50]	[399]	5	hSpCas9	negative selection	12192155
35640533	35640556	10	+	28162770	OCIAML2	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	0.6723281285998819	[29]	[264]	6	hSpCas9	negative selection	12192156
35640433	35640456	10	-	28162770	OCIAML2	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.569784443203747	[21]	[180]	5	hSpCas9	negative selection	12192157
35640283	35640306	10	-	28162770	OCIAML2	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-0.3222379853494901	[29]	[132]	-3	hSpCas9	negative selection	12192158
35640402	35640425	10	-	28162770	OCIAML3	viability	GAGAAGGTGGCGTGCAGCGGTGG	FZD8	ENSG00000177283	0.267472495594409	[70]	[257]	2	hSpCas9	negative selection	12361515
35640230	35640253	10	+	28162770	OCIAML3	viability	GAAGACCACGGTGCACAGCGCGG	FZD8	ENSG00000177283	0.17939994981010315	[42]	[146]	1	hSpCas9	negative selection	12361516
35640050	35640073	10	+	28162770	OCIAML3	viability	GCTGAGCGCCAGCACCGCGATGG	FZD8	ENSG00000177283	-0.12768963610162598	[37]	[104]	-1	hSpCas9	negative selection	12361517
35641367	35641390	10	+	28162770	OCIAML3	viability	GCGCTGCAGCAGCGCCAAGGCGG	FZD8	ENSG00000177283	-0.2111505467944691	[50]	[132]	-2	hSpCas9	negative selection	12361518
35641351	35641374	10	-	28162770	OCIAML3	viability	GCAGCGCTCTAGCGGCGCTGCGG	FZD8	ENSG00000177283	0.6337982771986492	[18]	[88]	6	hSpCas9	negative selection	12361519
35640888	35640911	10	-	28162770	OCIAML3	viability	GAGCAGCCGCCTTCGGGCAGCGG	FZD8	ENSG00000177283	-0.016462611165490026	[64]	[193]	0	hSpCas9	negative selection	12361520
35640584	35640607	10	+	28162770	OCIAML3	viability	GCCGATCCAGAAGACGGTGAAGG	FZD8	ENSG00000177283	0.4263410050676393	[87]	[356]	4	hSpCas9	negative selection	12361521
35640533	35640556	10	+	28162770	OCIAML3	viability	GAAGGTGGAGACGGTGGCGAAGG	FZD8	ENSG00000177283	-0.3556029009990842	[63]	[150]	-3	hSpCas9	negative selection	12361522
35640433	35640456	10	-	28162770	OCIAML3	viability	GGGCTACCTAGTGCGCCTGGTGG	FZD8	ENSG00000177283	0.48616270835982034	[34]	[147]	4	hSpCas9	negative selection	12361523
35640283	35640306	10	-	28162770	OCIAML3	viability	GTACGAGGAGCTGGGCGCGGTGG	FZD8	ENSG00000177283	-0.6746261005324479	[45]	[86]	-5	hSpCas9	negative selection	12361524