Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:2868
• Symbol:GRK4
• Description:G protein-coupled receptor kinase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/GRK4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
3013759	3013782	4	+	26472758	Jiyoye	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	2.6295678028423217	[29]	[139]	9	hSpCas9	negative selection	67406
2964070	2964093	4	+	26472758	Jiyoye	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	6.337912719068759	[0]	[60]	9	hSpCas9	negative selection	67408
3019792	3019815	4	+	26472758	Jiyoye	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	-0.465994596258644	[184]	[100]	-3	hSpCas9	negative selection	67409
3029310	3029333	4	+	26472758	Jiyoye	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.7291034763932356	[43]	[54]	5	hSpCas9	negative selection	67410
3037496	3037519	4	-	26472758	Jiyoye	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	-0.18827949303292513	[206]	[136]	-1	hSpCas9	negative selection	67411
3004255	3004278	4	-	26472758	Jiyoye	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.49610910992616175	[172]	[183]	4	hSpCas9	negative selection	67412
3019686	3019709	4	+	26472758	Jiyoye	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	-0.4296887827144533	[283]	[158]	-3	hSpCas9	negative selection	67413
3027931	3027954	4	-	26472758	Jiyoye	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.09279409567185912	[142]	[114]	0	hSpCas9	negative selection	67414
3027945	3027968	4	+	26472758	Jiyoye	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	-1.6843229729796227	[178]	[41]	-8	hSpCas9	negative selection	67415
3037403	3037426	4	+	26472758	Jiyoye	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.3115977215236421	[155]	[145]	2	hSpCas9	negative selection	67416
3013759	3013782	4	+	26472758	KBM7	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	-0.36963152091460066	[606,407]	[202,162]	-3	hSpCas9	negative selection	258524
2964070	2964093	4	+	26472758	KBM7	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-1.9741494507599342	[91,244]	[7,32]	-8	hSpCas9	negative selection	258526
3019792	3019815	4	+	26472758	KBM7	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.36078787460921985	[662,350]	[222,364]	4	hSpCas9	negative selection	258527
3029310	3029333	4	+	26472758	KBM7	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	-0.2684921464156329	[241,120]	[72,64]	-3	hSpCas9	negative selection	258528
3037496	3037519	4	-	26472758	KBM7	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.5134278248685732	[832,662]	[665,348]	5	hSpCas9	negative selection	258529
3004255	3004278	4	-	26472758	KBM7	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.06477733686629317	[968,783]	[541,326]	0	hSpCas9	negative selection	258530
3019686	3019709	4	+	26472758	KBM7	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.26329853522804714	[710,946]	[487,466]	2	hSpCas9	negative selection	258531
3027931	3027954	4	-	26472758	KBM7	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.27261784167764846	[613,617]	[347,354]	3	hSpCas9	negative selection	258532
3027945	3027968	4	+	26472758	KBM7	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.3504942839490801	[268,190]	[151,121]	4	hSpCas9	negative selection	258533
3037403	3037426	4	+	26472758	KBM7	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.45570534987050537	[556,421]	[364,265]	5	hSpCas9	negative selection	258534
3013759	3013782	4	+	26472758	Raji	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.6098838759027826	[95]	[33]	6	hSpCas9	negative selection	449642
2964070	2964093	4	+	26472758	Raji	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.6255145276165468	[80]	[28]	6	hSpCas9	negative selection	449644
3019792	3019815	4	+	26472758	Raji	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	-0.09116214400848063	[279]	[60]	-1	hSpCas9	negative selection	449645
3029310	3029333	4	+	26472758	Raji	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.429311630260962	[127]	[39]	4	hSpCas9	negative selection	449646
3037496	3037519	4	-	26472758	Raji	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.2419880010829204	[316]	[86]	2	hSpCas9	negative selection	449647
3004255	3004278	4	-	26472758	Raji	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.35779033287964396	[305]	[90]	3	hSpCas9	negative selection	449648
3019686	3019709	4	+	26472758	Raji	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.2115723856455709	[453]	[121]	2	hSpCas9	negative selection	449649
3027931	3027954	4	-	26472758	Raji	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	1.3100682852925614	[357]	[205]	9	hSpCas9	negative selection	449650
3027945	3027968	4	+	26472758	Raji	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.1562931358545459	[173]	[44]	1	hSpCas9	negative selection	449651
3037403	3037426	4	+	26472758	Raji	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	-0.09939668692824155	[336]	[72]	-1	hSpCas9	negative selection	449652
3013759	3013782	4	+	26472758	K562	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	-0.40628157029631073	[448]	[285]	-3	hSpCas9	negative selection	640760
2964070	2964093	4	+	26472758	K562	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	1.583905193938114	[97]	[247]	9	hSpCas9	negative selection	640762
3019792	3019815	4	+	26472758	K562	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.7150797331686267	[476]	[660]	6	hSpCas9	negative selection	640763
3029310	3029333	4	+	26472758	K562	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.7315339049894586	[121]	[170]	6	hSpCas9	negative selection	640764
3037496	3037519	4	-	26472758	K562	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.558579939510119	[595]	[740]	4	hSpCas9	negative selection	640765
3004255	3004278	4	-	26472758	K562	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.14703392300574625	[765]	[715]	1	hSpCas9	negative selection	640766
3019686	3019709	4	+	26472758	K562	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.8109378843351224	[760]	[1126]	6	hSpCas9	negative selection	640767
3027931	3027954	4	-	26472758	K562	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	1.1274625813205976	[487]	[899]	8	hSpCas9	negative selection	640768
3027945	3027968	4	+	26472758	K562	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	-0.4630277795797043	[257]	[157]	-3	hSpCas9	negative selection	640769
3037403	3037426	4	+	26472758	K562	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.9813843218326531	[362]	[604]	8	hSpCas9	negative selection	640770
2963970	2963993	4	+	26627737	DLD1	viability	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	-0.3803922626263273	[514]	[173,101,97]	-4	hSpCas9	negative selection	824929
2965306	2965329	4	-	26627737	DLD1	viability	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	-0.16161840578293596	[1796]	[615,334,541]	-2	hSpCas9	negative selection	824930
2984580	2984603	4	-	26627737	DLD1	viability	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.08234723997227839	[454]	[99,125,170]	-1	hSpCas9	negative selection	824931
3013694	3013717	4	+	26627737	DLD1	viability	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.8591122557618337	[154]	[120,69,73]	8	hSpCas9	negative selection	824932
3019688	3019711	4	+	26627737	DLD1	viability	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.649275826223144	[219]	[40,167,115]	6	hSpCas9	negative selection	824933
3035454	3035477	4	-	26627737	DLD1	viability	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.043039897165956964	[555]	[157,234,150]	0	hSpCas9	negative selection	824934
2963970	2963993	4	+	26627737	GBM cells	viability after 5 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	-0.873675629011242	[122]	[32,38]	-8	hSpCas9	negative selection	907244
2965306	2965329	4	-	26627737	GBM cells	viability after 5 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.15750801004773018	[921]	[627,474]	2	hSpCas9	negative selection	907245
2984580	2984603	4	-	26627737	GBM cells	viability after 5 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.014102823519674623	[176]	[107,79]	0	hSpCas9	negative selection	907246
3013694	3013717	4	+	26627737	GBM cells	viability after 5 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.7207683666384049	[98]	[95,78]	8	hSpCas9	negative selection	907247
3019688	3019711	4	+	26627737	GBM cells	viability after 5 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.9490830316692642	[269]	[56,92]	-9	hSpCas9	negative selection	907248
3035454	3035477	4	-	26627737	GBM cells	viability after 5 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.16248666977845763	[215]	[81,124]	-3	hSpCas9	negative selection	907249
2963970	2963993	4	+	26627737	GBM cells	viability after 13 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.13738348790880228	[122]	[52,89]	1	hSpCas9	negative selection	989559
2965306	2965329	4	-	26627737	GBM cells	viability after 13 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.1990153245270334	[921]	[667,497]	2	hSpCas9	negative selection	989560
2984580	2984603	4	-	26627737	GBM cells	viability after 13 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.2103351929658519	[176]	[98,69]	-3	hSpCas9	negative selection	989561
3013694	3013717	4	+	26627737	GBM cells	viability after 13 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.6247152808857958	[98]	[73,89]	7	hSpCas9	negative selection	989562
3019688	3019711	4	+	26627737	GBM cells	viability after 13 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.08296308631216545	[269]	[209,79]	-1	hSpCas9	negative selection	989563
3035454	3035477	4	-	26627737	GBM cells	viability after 13 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.14116585718607125	[215]	[97,112]	-2	hSpCas9	negative selection	989564
2963970	2963993	4	+	26627737	GBM cells	viability after 21 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	-1.3643097431732392	[122]	[26,24]	-8	hSpCas9	negative selection	1071874
2965306	2965329	4	-	26627737	GBM cells	viability after 21 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.268395271221634	[921]	[630,577]	3	hSpCas9	negative selection	1071875
2984580	2984603	4	-	26627737	GBM cells	viability after 21 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.1315884088451862	[176]	[92,82]	-1	hSpCas9	negative selection	1071876
3013694	3013717	4	+	26627737	GBM cells	viability after 21 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	1.158702052359316	[98]	[129,110]	9	hSpCas9	negative selection	1071877
3019688	3019711	4	+	26627737	GBM cells	viability after 21 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.2286569219592888	[269]	[162,179]	2	hSpCas9	negative selection	1071878
3035454	3035477	4	-	26627737	GBM cells	viability after 21 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.22280522201955474	[215]	[110,90]	-2	hSpCas9	negative selection	1071879
2963970	2963993	4	+	26627737	RPE1	viability after 9 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	1.1896737953227714	[93]	[67,65]	7	hSpCas9	negative selection	1154189
2965306	2965329	4	-	26627737	RPE1	viability after 9 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.35842189729875606	[3323]	[993,1772]	2	hSpCas9	negative selection	1154190
2984580	2984603	4	-	26627737	RPE1	viability after 9 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.16580752735948134	[554]	[152,248]	1	hSpCas9	negative selection	1154191
3013694	3013717	4	+	26627737	RPE1	viability after 9 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-1.2817889026803098	[506]	[80,44]	-7	hSpCas9	negative selection	1154192
3019688	3019711	4	+	26627737	RPE1	viability after 9 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.5897038696442016	[812]	[138,207]	-4	hSpCas9	negative selection	1154193
3035454	3035477	4	-	26627737	RPE1	viability after 9 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.44354373212060283	[397]	[175,160]	3	hSpCas9	negative selection	1154194
2963970	2963993	4	+	26627737	RPE1	viability after 12 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	2.6673098503384978	[93]	[225,90]	9	hSpCas9	negative selection	1236504
2965306	2965329	4	-	26627737	RPE1	viability after 12 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.7133318107325102	[3323]	[1284,1653]	4	hSpCas9	negative selection	1236505
2984580	2984603	4	-	26627737	RPE1	viability after 12 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.24900224410332558	[554]	[149,205]	1	hSpCas9	negative selection	1236506
3013694	3013717	4	+	26627737	RPE1	viability after 12 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.2786999451292005	[506]	[121,101]	-2	hSpCas9	negative selection	1236507
3019688	3019711	4	+	26627737	RPE1	viability after 12 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.26728795020389867	[812]	[129,235]	-2	hSpCas9	negative selection	1236508
3035454	3035477	4	-	26627737	RPE1	viability after 12 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.014927842555241044	[397]	[82,129]	0	hSpCas9	negative selection	1236509
2963970	2963993	4	+	26627737	RPE1	viability after 15 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	2.755454582728468	[93]	[316,46]	9	hSpCas9	negative selection	1318819
2965306	2965329	4	-	26627737	RPE1	viability after 15 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.6960037313146707	[3323]	[1535,1510]	4	hSpCas9	negative selection	1318820
2984580	2984603	4	-	26627737	RPE1	viability after 15 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.5658599352526601	[554]	[209,253]	3	hSpCas9	negative selection	1318821
3013694	3013717	4	+	26627737	RPE1	viability after 15 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.44280825512809785	[506]	[160,51]	-3	hSpCas9	negative selection	1318822
3019688	3019711	4	+	26627737	RPE1	viability after 15 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.07813690501016983	[812]	[225,209]	0	hSpCas9	negative selection	1318823
3035454	3035477	4	-	26627737	RPE1	viability after 15 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.5859843757774245	[397]	[140,195]	3	hSpCas9	negative selection	1318824
2963970	2963993	4	+	26627737	RPE1	viability after 18 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	2.0560813793914496	[93]	[148,58]	8	hSpCas9	negative selection	1401134
2965306	2965329	4	-	26627737	RPE1	viability after 18 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.9915798505282658	[3323]	[1583,1996]	6	hSpCas9	negative selection	1401135
2984580	2984603	4	-	26627737	RPE1	viability after 18 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.12530364095009916	[554]	[131,142]	-1	hSpCas9	negative selection	1401136
3013694	3013717	4	+	26627737	RPE1	viability after 18 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.7507631746853396	[506]	[104,55]	-5	hSpCas9	negative selection	1401137
3019688	3019711	4	+	26627737	RPE1	viability after 18 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.3458200342571794	[812]	[273,283]	2	hSpCas9	negative selection	1401138
3035454	3035477	4	-	26627737	RPE1	viability after 18 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.1659164578447705	[397]	[58,134]	-1	hSpCas9	negative selection	1401139
2963970	2963993	4	+	26627737	HeLa	viability after 8 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	-1.019985727126317	[116]	[36,1,37]	-8	hSpCas9	negative selection	1483449
2965306	2965329	4	-	26627737	HeLa	viability after 8 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.5579481245398075	[1339]	[1128,754,757]	5	hSpCas9	negative selection	1483450
2984580	2984603	4	-	26627737	HeLa	viability after 8 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-1.030301247164643	[353]	[142,5,90]	-8	hSpCas9	negative selection	1483451
3013694	3013717	4	+	26627737	HeLa	viability after 8 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.38784334125403275	[293]	[336,12,187]	3	hSpCas9	negative selection	1483452
3019688	3019711	4	+	26627737	HeLa	viability after 8 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.04811106589809906	[370]	[132,198,132]	0	hSpCas9	negative selection	1483453
3035454	3035477	4	-	26627737	HeLa	viability after 8 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.038915527506290425	[399]	[189,274,55]	0	hSpCas9	negative selection	1483454
2963970	2963993	4	+	26627737	HeLa	viability after 12 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.28034560837942624	[116]	[65,33,78]	2	hSpCas9	negative selection	1565764
2965306	2965329	4	-	26627737	HeLa	viability after 12 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.5593410721922685	[1339]	[1052,617,804]	5	hSpCas9	negative selection	1565765
2984580	2984603	4	-	26627737	HeLa	viability after 12 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.23759227572041194	[353]	[171,148,49]	-2	hSpCas9	negative selection	1565766
3013694	3013717	4	+	26627737	HeLa	viability after 12 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.39485967490150015	[293]	[112,52,115]	-4	hSpCas9	negative selection	1565767
3019688	3019711	4	+	26627737	HeLa	viability after 12 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.39122878961371216	[370]	[68,185,86]	-3	hSpCas9	negative selection	1565768
3035454	3035477	4	-	26627737	HeLa	viability after 12 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.4995647011504063	[399]	[70,205,62]	-4	hSpCas9	negative selection	1565769
2963970	2963993	4	+	26627737	HeLa	viability after 15 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.2856691592109135	[116]	[101,20,49]	2	hSpCas9	negative selection	1648079
2965306	2965329	4	-	26627737	HeLa	viability after 15 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.6601761453190629	[1339]	[632,769,1212]	5	hSpCas9	negative selection	1648080
2984580	2984603	4	-	26627737	HeLa	viability after 15 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.8079795053276592	[353]	[63,90,92]	-6	hSpCas9	negative selection	1648081
3013694	3013717	4	+	26627737	HeLa	viability after 15 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.16476396968609752	[293]	[294,60,36]	1	hSpCas9	negative selection	1648082
3019688	3019711	4	+	26627737	HeLa	viability after 15 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.598006617611053	[370]	[190,342,145]	5	hSpCas9	negative selection	1648083
3035454	3035477	4	-	26627737	HeLa	viability after 15 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.5248309592082038	[399]	[94,140,102]	-4	hSpCas9	negative selection	1648084
2963970	2963993	4	+	26627737	HeLa	viability after 18 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.2837576618554327	[116]	[66,18,49]	2	hSpCas9	negative selection	1730394
2965306	2965329	4	-	26627737	HeLa	viability after 18 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.6743995306016921	[1339]	[428,652,1212]	5	hSpCas9	negative selection	1730395
2984580	2984603	4	-	26627737	HeLa	viability after 18 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.7309806778104936	[353]	[47,79,92]	-6	hSpCas9	negative selection	1730396
3013694	3013717	4	+	26627737	HeLa	viability after 18 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.17059459019282786	[293]	[200,47,36]	1	hSpCas9	negative selection	1730397
3019688	3019711	4	+	26627737	HeLa	viability after 18 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.5974711079861881	[370]	[123,288,145]	5	hSpCas9	negative selection	1730398
3035454	3035477	4	-	26627737	HeLa	viability after 18 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.41474413034360835	[399]	[76,121,102]	-4	hSpCas9	negative selection	1730399
2963970	2963993	4	+	26627737	HCT116	viability after 6 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	1.1312087276248652	[37]	[34,0]	6	hSpCas9	negative selection	1812709
2965306	2965329	4	-	26627737	HCT116	viability after 6 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.43033732092905685	[2419]	[667,426]	2	hSpCas9	negative selection	1812710
2984580	2984603	4	-	26627737	HCT116	viability after 6 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.4075297519183806	[520]	[136,92]	2	hSpCas9	negative selection	1812711
3013694	3013717	4	+	26627737	HCT116	viability after 6 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.5116463009184845	[419]	[35,51]	-3	hSpCas9	negative selection	1812712
3019688	3019711	4	+	26627737	HCT116	viability after 6 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.005657925047013568	[557]	[89,86]	0	hSpCas9	negative selection	1812713
3035454	3035477	4	-	26627737	HCT116	viability after 6 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.21991708049097447	[862]	[120,113]	-1	hSpCas9	negative selection	1812714
2963970	2963993	4	+	26627737	HCT116	viability after 8 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	2.3495219771103324	[32]	[74,133,68]	9	hSpCas9	negative selection	1895024
2965306	2965329	4	-	26627737	HCT116	viability after 8 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.24360092664831012	[1097]	[672,743,730]	2	hSpCas9	negative selection	1895025
2984580	2984603	4	-	26627737	HCT116	viability after 8 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.6902963035209825	[170]	[188,132,134]	6	hSpCas9	negative selection	1895026
3013694	3013717	4	+	26627737	HCT116	viability after 8 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.322279656285579	[288]	[56,126,195]	-4	hSpCas9	negative selection	1895027
3019688	3019711	4	+	26627737	HCT116	viability after 8 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.28688752974697496	[211]	[117,156,151]	3	hSpCas9	negative selection	1895028
3035454	3035477	4	-	26627737	HCT116	viability after 8 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.20828215218150792	[300]	[112,161,154]	-2	hSpCas9	negative selection	1895029
2963970	2963993	4	+	26627737	HCT116	viability after 9 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	2.2422955493198113	[37]	[66,32]	9	hSpCas9	negative selection	1977339
2965306	2965329	4	-	26627737	HCT116	viability after 9 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.23820381422763282	[2419]	[540,936]	1	hSpCas9	negative selection	1977340
2984580	2984603	4	-	26627737	HCT116	viability after 9 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-1.8102944883382523	[520]	[18,55]	-8	hSpCas9	negative selection	1977341
3013694	3013717	4	+	26627737	HCT116	viability after 9 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.16617956253740784	[419]	[109,91]	-1	hSpCas9	negative selection	1977342
3019688	3019711	4	+	26627737	HCT116	viability after 9 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.8517026052907554	[557]	[579,22]	6	hSpCas9	negative selection	1977343
3035454	3035477	4	-	26627737	HCT116	viability after 9 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.8362945774633426	[862]	[137,121]	-5	hSpCas9	negative selection	1977344
2963970	2963993	4	+	26627737	HCT116	viability after 12 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	2.8481573410695	[32]	[79,100,196]	9	hSpCas9	negative selection	2059654
2965306	2965329	4	-	26627737	HCT116	viability after 12 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.16699417490947677	[1097]	[707,596,631]	1	hSpCas9	negative selection	2059655
2984580	2984603	4	-	26627737	HCT116	viability after 12 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.6777811993078653	[170]	[192,104,127]	6	hSpCas9	negative selection	2059656
3013694	3013717	4	+	26627737	HCT116	viability after 12 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.36372321931317353	[288]	[17,200,382]	3	hSpCas9	negative selection	2059657
3019688	3019711	4	+	26627737	HCT116	viability after 12 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.5309494178724861	[211]	[73,134,23]	-5	hSpCas9	negative selection	2059658
3035454	3035477	4	-	26627737	HCT116	viability after 12 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.0012145073315777792	[300]	[241,125,97]	0	hSpCas9	negative selection	2059659
2963970	2963993	4	+	26627737	HCT116	viability after 15 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	1.6683052802033032	[32]	[60,75,43]	9	hSpCas9	negative selection	2141969
2965306	2965329	4	-	26627737	HCT116	viability after 15 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.03168749405575344	[1097]	[605,591,729]	0	hSpCas9	negative selection	2141970
2984580	2984603	4	-	26627737	HCT116	viability after 15 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.9501735592129705	[170]	[173,94,296]	7	hSpCas9	negative selection	2141971
3013694	3013717	4	+	26627737	HCT116	viability after 15 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.24872534240436536	[288]	[46,238,121]	-3	hSpCas9	negative selection	2141972
3019688	3019711	4	+	26627737	HCT116	viability after 15 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.05355737431786245	[211]	[181,90,112]	0	hSpCas9	negative selection	2141973
3035454	3035477	4	-	26627737	HCT116	viability after 15 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	-0.19830393536034732	[300]	[153,197,100]	-2	hSpCas9	negative selection	2141974
2963970	2963993	4	+	26627737	HCT116	viability after 18 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	2.780367129206506	[32]	[51,165,106]	9	hSpCas9	negative selection	2224284
2965306	2965329	4	-	26627737	HCT116	viability after 18 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	-0.009831608080875354	[1097]	[739,419,423]	0	hSpCas9	negative selection	2224285
2984580	2984603	4	-	26627737	HCT116	viability after 18 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	1.6122487699639536	[170]	[423,115,225]	9	hSpCas9	negative selection	2224286
3013694	3013717	4	+	26627737	HCT116	viability after 18 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.2187482416024748	[288]	[170,122,197]	2	hSpCas9	negative selection	2224287
3019688	3019711	4	+	26627737	HCT116	viability after 18 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.44831668430164273	[211]	[145,48,29]	-4	hSpCas9	negative selection	2224288
3035454	3035477	4	-	26627737	HCT116	viability after 18 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.2771303859155772	[300]	[218,98,217]	2	hSpCas9	negative selection	2224289
2964070	2964093	4	+	24336569	HL60	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-0.6078805915464833	[995]	[1382]	-5	hSpCas9	negative selection	2268446
2964093	2964116	4	-	24336569	HL60	viability	CGCTTTCAGCAGCAGCGAGTTGG	GRK4	ENSG00000125388	0.22825180479372664	[782]	[1940]	2	hSpCas9	negative selection	2268447
2964101	2964124	4	+	24336569	HL60	viability	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	0.43585968321689683	[523]	[1499]	4	hSpCas9	negative selection	2268448
2988744	2988767	4	+	24336569	HL60	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.2051814041213761	[802]	[1958]	2	hSpCas9	negative selection	2268449
2988759	2988782	4	-	24336569	HL60	viability	CTGAAGAGACGTCTTCCTATCGG	GRK4	ENSG00000125388	0.295505357816428	[503]	[1308]	3	hSpCas9	negative selection	2268450
2988793	2988816	4	+	24336569	HL60	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	1.0857181337498776	[233]	[1050]	8	hSpCas9	negative selection	2268451
2988801	2988824	4	-	24336569	HL60	viability	TCAATGTGCCTCTTTAGAGTGGG	GRK4	ENSG00000125388	0.2264059532709714	[329]	[816]	2	hSpCas9	negative selection	2268452
2988809	2988832	4	+	24336569	HL60	viability	AAAGAGGCACATTGAATTCTTGG	GRK4	ENSG00000125388	0.840148000686388	[259]	[984]	7	hSpCas9	negative selection	2268453
2988818	2988841	4	+	24336569	HL60	viability	CATTGAATTCTTGGATGCAGTGG	GRK4	ENSG00000125388	0.6204203192037714	[690]	[2247]	5	hSpCas9	negative selection	2268454
2992220	2992243	4	+	24336569	HL60	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.4617045632056718	[536]	[1564]	4	hSpCas9	negative selection	2268455
2964070	2964093	4	+	24336569	KBM7	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.6088567490808326	[563]	[2345]	5	hSpCas9	negative selection	2335623
2964093	2964116	4	-	24336569	KBM7	viability	CGCTTTCAGCAGCAGCGAGTTGG	GRK4	ENSG00000125388	-0.2738651054934557	[675]	[1524]	-2	hSpCas9	negative selection	2335624
2964101	2964124	4	+	24336569	KBM7	viability	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	-0.47139565554986096	[396]	[780]	-4	hSpCas9	negative selection	2335625
2988744	2988767	4	+	24336569	KBM7	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.40467324820437944	[582]	[2104]	4	hSpCas9	negative selection	2335626
2988759	2988782	4	-	24336569	KBM7	viability	CTGAAGAGACGTCTTCCTATCGG	GRK4	ENSG00000125388	-0.1767964668322215	[912]	[2202]	-1	hSpCas9	negative selection	2335627
2988793	2988816	4	+	24336569	KBM7	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.36949088034193334	[295]	[1042]	3	hSpCas9	negative selection	2335628
2988801	2988824	4	-	24336569	KBM7	viability	TCAATGTGCCTCTTTAGAGTGGG	GRK4	ENSG00000125388	0.6346169555219554	[225]	[956]	6	hSpCas9	negative selection	2335629
2988809	2988832	4	+	24336569	KBM7	viability	AAAGAGGCACATTGAATTCTTGG	GRK4	ENSG00000125388	0.3068592176604885	[237]	[802]	3	hSpCas9	negative selection	2335630
2988818	2988841	4	+	24336569	KBM7	viability	CATTGAATTCTTGGATGCAGTGG	GRK4	ENSG00000125388	-0.23923327737867955	[633]	[1464]	-2	hSpCas9	negative selection	2335631
2992220	2992243	4	+	24336569	KBM7	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.016996552645409307	[449]	[1212]	0	hSpCas9	negative selection	2335632
2970428	2970451	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGGCGGATCACGAGGTCCAG	GRK4	ENSG00000125388	3.672125698082768	[96,21]	[254,70]	9	dCas9-VP64	positive selection	2407960
2998268	2998291	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATTGCTTGAACCCGGGAGGAGG	GRK4	ENSG00000125388	0.3272337489211984	[8,246]	[5,67]	1	dCas9-VP64	positive selection	2421302
2999397	2999420	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCAACAGTGTTGAGAGGTGGG	GRK4	ENSG00000125388	-0.8742539338118509	[161,27]	[9,10]	-5	dCas9-VP64	positive selection	2422123
2996940	2996963	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCGCACCTAG	GRK4	ENSG00000125388	-0.89146844564302	[3,30]	[1,1]	-5	dCas9-VP64	positive selection	2429420
2976887	2976910	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGACCGGGG	GRK4	ENSG00000125388	0.3844762753670785	[5,31]	[5,4]	1	dCas9-VP64	positive selection	2432515
2987706	2987729	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGGTGGGTGGATCACTTGAAG	GRK4	ENSG00000125388	0.9269503688862448	[9,0]	[1,1]	4	dCas9-VP64	positive selection	2463096
3033841	3033864	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAAATGCTGGGATTACGGG	GRK4	ENSG00000125388	0.20161513672590614	[46,60]	[10,15]	1	dCas9-VP64	positive selection	2475364
2970428	2970451	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGGCGGATCACGAGGTCCAG	GRK4	ENSG00000125388	2.475771989876751	[78,50]	[99,137]	9	dCas9-VP64	positive selection	2503215
2998268	2998291	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATTGCTTGAACCCGGGAGGAGG	GRK4	ENSG00000125388	0.646844560450541	[111,36]	[52,24]	5	dCas9-VP64	positive selection	2516557
2999397	2999420	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCAACAGTGTTGAGAGGTGGG	GRK4	ENSG00000125388	0.7330306885412703	[44,16]	[25,7]	5	dCas9-VP64	positive selection	2517378
2996940	2996963	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCGCACCTAG	GRK4	ENSG00000125388	0.12972035773098467	[57,36]	[16,15]	1	dCas9-VP64	positive selection	2524675
2976887	2976910	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGACCGGGG	GRK4	ENSG00000125388	0.9229581232819051	[29,251]	[8,157]	6	dCas9-VP64	positive selection	2527770
2987706	2987729	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGGTGGGTGGATCACTTGAAG	GRK4	ENSG00000125388	-0.7008385215102662	[31,39]	[9,2]	-6	dCas9-VP64	positive selection	2558351
3033841	3033864	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAAATGCTGGGATTACGGG	GRK4	ENSG00000125388	-0.42275240861415275	[53,301]	[32,50]	-4	dCas9-VP64	positive selection	2570619
3007737	3007760	4	+	27260157	DLD1	viability	GTTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.151686864867945	[]	[]	3	hSpCas9	negative selection	2576879
2992236	2992259	4	+	27260157	DLD1	viability	GATGAGGACCGAAGTGATTGTGG	GRK4	ENSG00000125388	-0.00777552273576513	[]	[]	0	hSpCas9	negative selection	2579773
2988793	2988816	4	+	27260157	DLD1	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.303453371905062	[]	[]	-2	hSpCas9	negative selection	2581710
2988796	2988819	4	-	27260157	DLD1	viability	GTGCCTCTTTAGAGTGGGTTTGG	GRK4	ENSG00000125388	0.518784917340393	[]	[]	8	hSpCas9	negative selection	2582554
2964101	2964124	4	+	27260157	DLD1	viability	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	-0.10538953476125	[]	[]	0	hSpCas9	negative selection	2584590
2988801	2988824	4	-	27260157	DLD1	viability	TCAATGTGCCTCTTTAGAGTGGG	GRK4	ENSG00000125388	-0.642434459433574	[]	[]	-5	hSpCas9	negative selection	2604167
2988744	2988767	4	+	27260157	DLD1	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.121275149081404	[]	[]	3	hSpCas9	negative selection	2609318
3004255	3004278	4	-	27260157	DLD1	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.603351640896565	[]	[]	-5	hSpCas9	negative selection	2610273
3004275	3004298	4	+	27260157	DLD1	viability	ATGTAGATTGGGACTGAAGGAGG	GRK4	ENSG00000125388	-0.264425998737046	[]	[]	-2	hSpCas9	negative selection	2612012
2964064	2964087	4	-	27260157	DLD1	viability	TGTTCTCGAGCTCCATGTCCTGG	GRK4	ENSG00000125388	-0.845750971496911	[]	[]	-6	hSpCas9	negative selection	2612841
2964070	2964093	4	+	27260157	DLD1	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.347058529346757	[]	[]	4	hSpCas9	negative selection	2615656
2988809	2988832	4	+	27260157	DLD1	viability	AAAGAGGCACATTGAATTCTTGG	GRK4	ENSG00000125388	0.86166157120425	[]	[]	9	hSpCas9	negative selection	2618504
2992220	2992243	4	+	27260157	DLD1	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.473650431878094	[]	[]	-4	hSpCas9	negative selection	2618998
2964093	2964116	4	-	27260157	DLD1	viability	CGCTTTCAGCAGCAGCGAGTTGG	GRK4	ENSG00000125388	-0.052867439958776	[]	[]	0	hSpCas9	negative selection	2619024
2984569	2984592	4	-	27260157	DLD1	viability	TCACTGCACTGGCTGACAGGAGG	GRK4	ENSG00000125388	-0.901758580194823	[]	[]	-6	hSpCas9	negative selection	2620878
2992231	2992254	4	-	27260157	DLD1	viability	ATCACTTCGGTCCTCATCATCGG	GRK4	ENSG00000125388	0.0380157012257641	[]	[]	0	hSpCas9	negative selection	2622559
2988818	2988841	4	+	27260157	DLD1	viability	CATTGAATTCTTGGATGCAGTGG	GRK4	ENSG00000125388	0.325069939708394	[]	[]	4	hSpCas9	negative selection	2640744
2984580	2984603	4	-	27260157	DLD1	viability	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.289401159454185	[]	[]	4	hSpCas9	negative selection	2641942
3007737	3007760	4	+	27260157	HT1080	viability	GTTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	-0.765465289658998	[]	[]	-8	hSpCas9	negative selection	2653009
2992236	2992259	4	+	27260157	HT1080	viability	GATGAGGACCGAAGTGATTGTGG	GRK4	ENSG00000125388	0.579029824299194	[]	[]	5	hSpCas9	negative selection	2655903
2988793	2988816	4	+	27260157	HT1080	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.428584062243311	[]	[]	-7	hSpCas9	negative selection	2657840
2988796	2988819	4	-	27260157	HT1080	viability	GTGCCTCTTTAGAGTGGGTTTGG	GRK4	ENSG00000125388	-0.329797066624356	[]	[]	-7	hSpCas9	negative selection	2658684
2964101	2964124	4	+	27260157	HT1080	viability	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	-0.467122906732308	[]	[]	-7	hSpCas9	negative selection	2660720
2988801	2988824	4	-	27260157	HT1080	viability	TCAATGTGCCTCTTTAGAGTGGG	GRK4	ENSG00000125388	-0.19105670276407	[]	[]	0	hSpCas9	negative selection	2680297
2988744	2988767	4	+	27260157	HT1080	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.166347289382539	[]	[]	0	hSpCas9	negative selection	2685448
3004255	3004278	4	-	27260157	HT1080	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.958712991284681	[]	[]	-8	hSpCas9	negative selection	2686403
3004275	3004298	4	+	27260157	HT1080	viability	ATGTAGATTGGGACTGAAGGAGG	GRK4	ENSG00000125388	0.343236550123179	[]	[]	3	hSpCas9	negative selection	2688142
2964064	2964087	4	-	27260157	HT1080	viability	TGTTCTCGAGCTCCATGTCCTGG	GRK4	ENSG00000125388	-1.56700201088641	[]	[]	-9	hSpCas9	negative selection	2688971
2964070	2964093	4	+	27260157	HT1080	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.817465734349374	[]	[]	7	hSpCas9	negative selection	2691786
2988809	2988832	4	+	27260157	HT1080	viability	AAAGAGGCACATTGAATTCTTGG	GRK4	ENSG00000125388	0.728052018263315	[]	[]	6	hSpCas9	negative selection	2694634
2992220	2992243	4	+	27260157	HT1080	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.981046866915727	[]	[]	-8	hSpCas9	negative selection	2695128
2964093	2964116	4	-	27260157	HT1080	viability	CGCTTTCAGCAGCAGCGAGTTGG	GRK4	ENSG00000125388	-0.377815433698796	[]	[]	-7	hSpCas9	negative selection	2695154
2984569	2984592	4	-	27260157	HT1080	viability	TCACTGCACTGGCTGACAGGAGG	GRK4	ENSG00000125388	0.0422183861693078	[]	[]	0	hSpCas9	negative selection	2697008
2992231	2992254	4	-	27260157	HT1080	viability	ATCACTTCGGTCCTCATCATCGG	GRK4	ENSG00000125388	0.151394053734856	[]	[]	1	hSpCas9	negative selection	2698689
2988818	2988841	4	+	27260157	HT1080	viability	CATTGAATTCTTGGATGCAGTGG	GRK4	ENSG00000125388	0.554883507153485	[]	[]	5	hSpCas9	negative selection	2716874
2984580	2984603	4	-	27260157	HT1080	viability	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.154631195652561	[]	[]	1	hSpCas9	negative selection	2718072
3007737	3007760	4	+	27260157	MKN45	viability	GTTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.246482969790242	[]	[]	5	hSpCas9	negative selection	2729139
2992236	2992259	4	+	27260157	MKN45	viability	GATGAGGACCGAAGTGATTGTGG	GRK4	ENSG00000125388	1.18502042564222	[]	[]	8	hSpCas9	negative selection	2732033
2988793	2988816	4	+	27260157	MKN45	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.677604361911849	[]	[]	-7	hSpCas9	negative selection	2733970
2988796	2988819	4	-	27260157	MKN45	viability	GTGCCTCTTTAGAGTGGGTTTGG	GRK4	ENSG00000125388	0.279662652622267	[]	[]	5	hSpCas9	negative selection	2734814
2964101	2964124	4	+	27260157	MKN45	viability	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	-0.555847177368855	[]	[]	-6	hSpCas9	negative selection	2736850
2988801	2988824	4	-	27260157	MKN45	viability	TCAATGTGCCTCTTTAGAGTGGG	GRK4	ENSG00000125388	-1.02311346330487	[]	[]	-8	hSpCas9	negative selection	2756427
2988744	2988767	4	+	27260157	MKN45	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.0447222528131727	[]	[]	0	hSpCas9	negative selection	2761578
3004255	3004278	4	-	27260157	MKN45	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-1.32794404630459	[]	[]	-8	hSpCas9	negative selection	2762533
3004275	3004298	4	+	27260157	MKN45	viability	ATGTAGATTGGGACTGAAGGAGG	GRK4	ENSG00000125388	0.0755408100216703	[]	[]	0	hSpCas9	negative selection	2764272
2964064	2964087	4	-	27260157	MKN45	viability	TGTTCTCGAGCTCCATGTCCTGG	GRK4	ENSG00000125388	-2.08347009912766	[]	[]	-9	hSpCas9	negative selection	2765101
2964070	2964093	4	+	27260157	MKN45	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-1.00792456381784	[]	[]	-8	hSpCas9	negative selection	2767916
2988809	2988832	4	+	27260157	MKN45	viability	AAAGAGGCACATTGAATTCTTGG	GRK4	ENSG00000125388	0.477729674769706	[]	[]	6	hSpCas9	negative selection	2770764
2992220	2992243	4	+	27260157	MKN45	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.16409762503547	[]	[]	0	hSpCas9	negative selection	2771258
2964093	2964116	4	-	27260157	MKN45	viability	CGCTTTCAGCAGCAGCGAGTTGG	GRK4	ENSG00000125388	-1.44697456612872	[]	[]	-8	hSpCas9	negative selection	2771284
2984569	2984592	4	-	27260157	MKN45	viability	TCACTGCACTGGCTGACAGGAGG	GRK4	ENSG00000125388	-0.633260739832341	[]	[]	-6	hSpCas9	negative selection	2773138
2992231	2992254	4	-	27260157	MKN45	viability	ATCACTTCGGTCCTCATCATCGG	GRK4	ENSG00000125388	-0.0505875217581162	[]	[]	0	hSpCas9	negative selection	2774819
2988818	2988841	4	+	27260157	MKN45	viability	CATTGAATTCTTGGATGCAGTGG	GRK4	ENSG00000125388	0.801467771266211	[]	[]	7	hSpCas9	negative selection	2793004
2984580	2984603	4	-	27260157	MKN45	viability	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.590582041576352	[]	[]	-6	hSpCas9	negative selection	2794202
3007737	3007760	4	+	27260157	RKO	viability	GTTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.855928973204652	[]	[]	8	hSpCas9	negative selection	2805269
2992236	2992259	4	+	27260157	RKO	viability	GATGAGGACCGAAGTGATTGTGG	GRK4	ENSG00000125388	0.591398794612209	[]	[]	3	hSpCas9	negative selection	2808163
2988793	2988816	4	+	27260157	RKO	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.793747696760263	[]	[]	-7	hSpCas9	negative selection	2810100
2988796	2988819	4	-	27260157	RKO	viability	GTGCCTCTTTAGAGTGGGTTTGG	GRK4	ENSG00000125388	0.497498884834808	[]	[]	2	hSpCas9	negative selection	2810944
2964101	2964124	4	+	27260157	RKO	viability	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	-0.5518938922993	[]	[]	-7	hSpCas9	negative selection	2812980
2988801	2988824	4	-	27260157	RKO	viability	TCAATGTGCCTCTTTAGAGTGGG	GRK4	ENSG00000125388	-0.497592843122748	[]	[]	-6	hSpCas9	negative selection	2832557
2988744	2988767	4	+	27260157	RKO	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.339302374656411	[]	[]	1	hSpCas9	negative selection	2837708
3004255	3004278	4	-	27260157	RKO	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.66339427904504	[]	[]	-7	hSpCas9	negative selection	2838663
3004275	3004298	4	+	27260157	RKO	viability	ATGTAGATTGGGACTGAAGGAGG	GRK4	ENSG00000125388	-7.96297341113596e-06	[]	[]	0	hSpCas9	negative selection	2840402
2964064	2964087	4	-	27260157	RKO	viability	TGTTCTCGAGCTCCATGTCCTGG	GRK4	ENSG00000125388	-0.331889957816364	[]	[]	-6	hSpCas9	negative selection	2841231
2964070	2964093	4	+	27260157	RKO	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.528288400155539	[]	[]	3	hSpCas9	negative selection	2844046
2988809	2988832	4	+	27260157	RKO	viability	AAAGAGGCACATTGAATTCTTGG	GRK4	ENSG00000125388	0.651489587790651	[]	[]	3	hSpCas9	negative selection	2846894
2992220	2992243	4	+	27260157	RKO	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.706921537075696	[]	[]	8	hSpCas9	negative selection	2847388
2964093	2964116	4	-	27260157	RKO	viability	CGCTTTCAGCAGCAGCGAGTTGG	GRK4	ENSG00000125388	-0.26812884398142	[]	[]	-1	hSpCas9	negative selection	2847414
2984569	2984592	4	-	27260157	RKO	viability	TCACTGCACTGGCTGACAGGAGG	GRK4	ENSG00000125388	-0.577695257054692	[]	[]	-7	hSpCas9	negative selection	2849268
2992231	2992254	4	-	27260157	RKO	viability	ATCACTTCGGTCCTCATCATCGG	GRK4	ENSG00000125388	-0.391474403070578	[]	[]	-6	hSpCas9	negative selection	2850949
2988818	2988841	4	+	27260157	RKO	viability	CATTGAATTCTTGGATGCAGTGG	GRK4	ENSG00000125388	0.531111146478348	[]	[]	3	hSpCas9	negative selection	2869134
2984580	2984603	4	-	27260157	RKO	viability	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.284236297605052	[]	[]	-5	hSpCas9	negative selection	2870332
3007737	3007760	4	+	27260157	SF268	viability	GTTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	-0.18897809544324	[]	[]	-1	hSpCas9	negative selection	2881399
2992236	2992259	4	+	27260157	SF268	viability	GATGAGGACCGAAGTGATTGTGG	GRK4	ENSG00000125388	0.482670588249078	[]	[]	7	hSpCas9	negative selection	2884293
2988793	2988816	4	+	27260157	SF268	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.506291752397983	[]	[]	7	hSpCas9	negative selection	2886230
2988796	2988819	4	-	27260157	SF268	viability	GTGCCTCTTTAGAGTGGGTTTGG	GRK4	ENSG00000125388	0.773488126519073	[]	[]	8	hSpCas9	negative selection	2887074
2964101	2964124	4	+	27260157	SF268	viability	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	-0.237411800198472	[]	[]	-2	hSpCas9	negative selection	2889110
2988801	2988824	4	-	27260157	SF268	viability	TCAATGTGCCTCTTTAGAGTGGG	GRK4	ENSG00000125388	-0.956153695230265	[]	[]	-6	hSpCas9	negative selection	2908687
2988744	2988767	4	+	27260157	SF268	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.109981217107226	[]	[]	-1	hSpCas9	negative selection	2913838
3004255	3004278	4	-	27260157	SF268	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.219720210368943	[]	[]	3	hSpCas9	negative selection	2914793
3004275	3004298	4	+	27260157	SF268	viability	ATGTAGATTGGGACTGAAGGAGG	GRK4	ENSG00000125388	-0.157038318752668	[]	[]	-1	hSpCas9	negative selection	2916532
2964064	2964087	4	-	27260157	SF268	viability	TGTTCTCGAGCTCCATGTCCTGG	GRK4	ENSG00000125388	-0.518623203952689	[]	[]	-4	hSpCas9	negative selection	2917361
2964070	2964093	4	+	27260157	SF268	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.78959359220001	[]	[]	8	hSpCas9	negative selection	2920176
2988809	2988832	4	+	27260157	SF268	viability	AAAGAGGCACATTGAATTCTTGG	GRK4	ENSG00000125388	0.594904614608565	[]	[]	8	hSpCas9	negative selection	2923024
2992220	2992243	4	+	27260157	SF268	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.253236842547831	[]	[]	4	hSpCas9	negative selection	2923518
2964093	2964116	4	-	27260157	SF268	viability	CGCTTTCAGCAGCAGCGAGTTGG	GRK4	ENSG00000125388	0.264704049195679	[]	[]	4	hSpCas9	negative selection	2923544
2984569	2984592	4	-	27260157	SF268	viability	TCACTGCACTGGCTGACAGGAGG	GRK4	ENSG00000125388	-0.518798827282764	[]	[]	-4	hSpCas9	negative selection	2925398
2992231	2992254	4	-	27260157	SF268	viability	ATCACTTCGGTCCTCATCATCGG	GRK4	ENSG00000125388	-0.257992442066029	[]	[]	-2	hSpCas9	negative selection	2927079
2988818	2988841	4	+	27260157	SF268	viability	CATTGAATTCTTGGATGCAGTGG	GRK4	ENSG00000125388	0.405888944763781	[]	[]	4	hSpCas9	negative selection	2945264
2984580	2984603	4	-	27260157	SF268	viability	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.637462269746226	[]	[]	-5	hSpCas9	negative selection	2946462
2964030	2964053	4	+	27013184	SW480	treatment with recombinant TRAIL	CTCGGTCTCGCAGAATCCGCCGG	GRK4	ENSG00000125388	0.14487565623562004	[153,143]	[41,112]	0	hSpCas9	positive selection	2959184
2964033	2964056	4	+	27013184	SW480	treatment with recombinant TRAIL	GGTCTCGCAGAATCCGCCGGCGG	GRK4	ENSG00000125388	-0.16666557409943072	[656,894]	[226,389]	0	hSpCas9	positive selection	2959185
2964101	2964124	4	+	27013184	SW480	treatment with recombinant TRAIL	CTGCTGCTGAAAGCGCGTCAAGG	GRK4	ENSG00000125388	0.30529772614136297	[522,462]	[78,527]	1	hSpCas9	positive selection	2959186
2964104	2964127	4	+	27013184	SW480	treatment with recombinant TRAIL	CTGCTGAAAGCGCGTCAAGGTGG	GRK4	ENSG00000125388	-0.2758238053186206	[85,106]	[31,36]	-1	hSpCas9	positive selection	2959187
2964105	2964128	4	+	27013184	SW480	treatment with recombinant TRAIL	TGCTGAAAGCGCGTCAAGGTGGG	GRK4	ENSG00000125388	-2.736346607019911	[118,263]	[18,1]	-8	hSpCas9	positive selection	2959188
2964112	2964135	4	+	27013184	SW480	treatment with recombinant TRAIL	AGCGCGTCAAGGTGGGTGCGCGG	GRK4	ENSG00000125388	1.2504305629428425	[272,177]	[253,209]	6	hSpCas9	positive selection	2959189
2964116	2964139	4	+	27013184	SW480	treatment with recombinant TRAIL	CGTCAAGGTGGGTGCGCGGCAGG	GRK4	ENSG00000125388	2.4484723689211605	[80,77]	[90,324]	9	hSpCas9	positive selection	2959190
3027890	3027913	4	+	27013184	SW480	treatment with recombinant TRAIL	AATAACATATTTGAACACACAGG	GRK4	ENSG00000125388	0.40099517792460027	[232,260]	[99,196]	2	hSpCas9	positive selection	2959191
3027900	3027923	4	+	27013184	SW480	treatment with recombinant TRAIL	TTGAACACACAGGACACATCCGG	GRK4	ENSG00000125388	0.021060195494228773	[305,366]	[49,282]	0	hSpCas9	positive selection	2959192
3027914	3027937	4	+	27013184	SW480	treatment with recombinant TRAIL	CACATCCGGATTTCAGACCTCGG	GRK4	ENSG00000125388	0.39377995702332247	[764,843]	[397,533]	2	hSpCas9	positive selection	2959193
3027919	3027942	4	+	27013184	SW480	treatment with recombinant TRAIL	CCGGATTTCAGACCTCGGTTTGG	GRK4	ENSG00000125388	-1.4128527148178716	[519,701]	[67,139]	-6	hSpCas9	positive selection	2959194
3027938	3027961	4	+	27013184	SW480	treatment with recombinant TRAIL	TTGGCCACAGAGATCCCAGAAGG	GRK4	ENSG00000125388	0.027985926939880335	[125,140]	[43,78]	0	hSpCas9	positive selection	2959195
3027971	3027994	4	+	27013184	SW480	treatment with recombinant TRAIL	CGAGGAAGAGTTGGAACAGTCGG	GRK4	ENSG00000125388	-2.3880740747858744	[46,43]	[4,1]	-8	hSpCas9	positive selection	2959196
3027979	3028002	4	+	27013184	SW480	treatment with recombinant TRAIL	AGTTGGAACAGTCGGCTACATGG	GRK4	ENSG00000125388	0.7211531931140944	[550,512]	[377,381]	3	hSpCas9	positive selection	2959197
3027980	3028003	4	+	27013184	SW480	treatment with recombinant TRAIL	GTTGGAACAGTCGGCTACATGGG	GRK4	ENSG00000125388	2.3361719722332808	[412,354]	[732,997]	8	hSpCas9	positive selection	2959198
3027991	3028014	4	+	27013184	SW480	treatment with recombinant TRAIL	CGGCTACATGGGTTCGTGAGAGG	GRK4	ENSG00000125388	-0.43441124006687626	[133,255]	[55,66]	-2	hSpCas9	positive selection	2959199
3027998	3028021	4	+	27013184	SW480	treatment with recombinant TRAIL	ATGGGTTCGTGAGAGGCTTTCGG	GRK4	ENSG00000125388	1.7548061729379665	[87,36]	[83,108]	7	hSpCas9	positive selection	2959200
3029230	3029253	4	+	27013184	SW480	treatment with recombinant TRAIL	ACGTTTAGTCCCGATTGGTGGGG	GRK4	ENSG00000125388	0.5991476726638518	[395,514]	[238,372]	3	hSpCas9	positive selection	2959201
3029236	3029259	4	+	27013184	SW480	treatment with recombinant TRAIL	AGTCCCGATTGGTGGGGACTTGG	GRK4	ENSG00000125388	0.02057174775059213	[182,236]	[68,121]	0	hSpCas9	positive selection	2959202
3029340	3029363	4	+	27013184	SW480	treatment with recombinant TRAIL	AAGAATCAAGAATGATACCGAGG	GRK4	ENSG00000125388	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2959203
3029384	3029407	4	+	27013184	SW480	treatment with recombinant TRAIL	AGGATGCCAAATCTATCTGCAGG	GRK4	ENSG00000125388	-0.12294888282106231	[435,705]	[223,217]	0	hSpCas9	positive selection	2959204
3029388	3029411	4	+	27013184	SW480	treatment with recombinant TRAIL	TGCCAAATCTATCTGCAGGATGG	GRK4	ENSG00000125388	-2.8666753757839407	[258,352]	[2,38]	-8	hSpCas9	positive selection	2959205
3029397	3029420	4	+	27013184	SW480	treatment with recombinant TRAIL	TATCTGCAGGATGGTAAGTCAGG	GRK4	ENSG00000125388	0.2545408850597235	[138,98]	[36,97]	1	hSpCas9	positive selection	2959206
3029408	3029431	4	+	27013184	SW480	treatment with recombinant TRAIL	TGGTAAGTCAGGCTCTGTAGAGG	GRK4	ENSG00000125388	0.5628967293734217	[108,103]	[79,50]	2	hSpCas9	positive selection	2959207
2963968	2963991	4	+	27013184	SW480	treatment with recombinant TRAIL	GGTGCCCGGCGAGCTATGCACGG	GRK4	ENSG00000125388	-1.465719405356651	[264,385]	[42,59]	-6	hSpCas9	positive selection	2959208
2963969	2963992	4	+	27013184	SW480	treatment with recombinant TRAIL	GTGCCCGGCGAGCTATGCACGGG	GRK4	ENSG00000125388	0.7853484993264834	[125,114]	[44,153]	4	hSpCas9	positive selection	2959209
3027919	3027942	4	-	27013184	SW480	treatment with recombinant TRAIL	CCAAACCGAGGTCTGAAATCCGG	GRK4	ENSG00000125388	1.0127736809565262	[86,153]	[110,89]	5	hSpCas9	positive selection	2959210
3027931	3027954	4	-	27013184	SW480	treatment with recombinant TRAIL	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	-0.17855839037275145	[90,107]	[35,39]	-1	hSpCas9	positive selection	2959211
3029390	3029413	4	-	27013184	SW480	treatment with recombinant TRAIL	TACCATCCTGCAGATAGATTTGG	GRK4	ENSG00000125388	-3.9731122494399975	[180,404]	[1,15]	-9	hSpCas9	positive selection	2959212
2963970	2963993	4	+	27013184	SW480	treatment with recombinant TRAIL	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	1.4265235774908536	[385,404]	[503,391]	6	hSpCas9	positive selection	2959213
3004255	3004278	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.1267660565583213	[4,3]	[4,1]	-2	hSpCas9	positive selection	2992085
2988745	2988768	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.09928798432492231	[5,5]	[5,4]	2	hSpCas9	positive selection	2992086
3019689	3019712	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.4498266154473217	[2,2]	[3,3]	8	hSpCas9	positive selection	2992087
2992244	2992267	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.4355473427024235	[5,4]	[5,6]	8	hSpCas9	positive selection	2992088
3004255	3004278	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.6540441535262626	[4,4]	[3,5]	9	hSpCas9	positive selection	3059943
2988745	2988768	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.08478236786201415	[5,5]	[5,2]	1	hSpCas9	positive selection	3059944
3019689	3019712	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.40166987929866965	[2,2]	[2,2]	7	hSpCas9	positive selection	3059945
2992244	2992267	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.005768486336646783	[5,5]	[5,2]	0	hSpCas9	positive selection	3059946
2988793	2988816		+	24336571	A375	resistance to PLX after 7 days	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.19904344250089245	[6,6]	[6,4]	-6	hSpCas9	positive selection	3117871
2992220	2992243		+	24336571	A375	resistance to PLX after 7 days	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.10408357775234589	[21,28]	[27,26]	3	hSpCas9	positive selection	3117872
2992244	2992267		-	24336571	A375	resistance to PLX after 7 days	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.11914822411550996	[31,38]	[29,34]	-4	hSpCas9	positive selection	3117873
2988793	2988816		+	24336571	A375	resistance to PLX after 14 days	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.18068178280145986	[7,5]	[2,1]	-2	hSpCas9	positive selection	3175664
2992220	2992243		+	24336571	A375	resistance to PLX after 14 days	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.35604116972188005	[18,29]	[8,7]	-4	hSpCas9	positive selection	3175665
2992244	2992267		-	24336571	A375	resistance to PLX after 14 days	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.44830463381471264	[26,39]	[9,11]	-5	hSpCas9	positive selection	3175666
2988793	2988816		+	24336571	A375	viability after 7 days	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-1.0468872489911893	[15]	[6,6]	-9	hSpCas9	negative selection	3233457
2992220	2992243		+	24336571	A375	viability after 7 days	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.0410019106375219	[25]	[21,28]	0	hSpCas9	negative selection	3233458
2992244	2992267		-	24336571	A375	viability after 7 days	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.5060367871951135	[52]	[31,38]	-6	hSpCas9	negative selection	3233459
2988793	2988816		+	24336571	A375	viability after 14 days	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-1.0575382369825521	[15]	[7,5]	-8	hSpCas9	negative selection	3291250
2992220	2992243		+	24336571	A375	viability after 14 days	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.004192739215020724	[25]	[18,29]	0	hSpCas9	negative selection	3291251
2992244	2992267		-	24336571	A375	viability after 14 days	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.5664250703525269	[52]	[26,39]	-6	hSpCas9	negative selection	3291252
2988744	2988767	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.5120308697592751	[224,203]	[0,2]	2	hSpCas9	positive selection	3352544
2992220	2992243	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	3.5062854320679064	[7,18]	[0,0]	9	hSpCas9	positive selection	3352545
2988793	2988816	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	3.0098950665056456	[17,19]	[0,0]	8	hSpCas9	positive selection	3352546
3004258	3004281	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	-1.2857056088094025	[372,372]	[0,0]	-8	hSpCas9	positive selection	3371749
3004316	3004339	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-1.4326717599736103	[412,412]	[0,0]	-8	hSpCas9	positive selection	3371750
2992244	2992267	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-1.1435532248363494	[337,337]	[0,0]	-7	hSpCas9	positive selection	3371751
3004255	3004278	4	-	26780180	HT29	viability (Avana library 4 designs)	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.265233395755793	[]	[]	0	hSpCas9	negative selection	3429287
2988744	2988767	4	+	26780180	HT29	viability (Avana library 4 designs)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.704936881618476	[]	[]	-8	hSpCas9	negative selection	3429288
3019688	3019711	4	+	26780180	HT29	viability (Avana library 4 designs)	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	1.60473657697745	[]	[]	6	hSpCas9	negative selection	3429289
2992244	2992267	4	-	26780180	HT29	viability (Avana library 4 designs)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.476098999741282	[]	[]	-7	hSpCas9	negative selection	3429290
2988744	2988767	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	2.0836460042064	[]	[]	3	hSpCas9	negative selection	3513887
3004255	3004278	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-6.46485115409826	[]	[]	-6	hSpCas9	negative selection	3513888
2992244	2992267	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-2.67001565313106	[]	[]	-3	hSpCas9	negative selection	3513889
3019688	3019711	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-1.34605820415227	[]	[]	-2	hSpCas9	negative selection	3513890
2988793	2988816	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-7.21074530464302	[]	[]	-6	hSpCas9	negative selection	3513891
3007739	3007762	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCCCATAACTACCTAAGAGGGG	GRK4	ENSG00000125388	1.03124837396233	[]	[]	1	hSpCas9	negative selection	3513892
2988744	2988767	4	+	26780180	A375	viability (Avana lentiGuide)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-1.56135388064079	[]	[]	-3	hSpCas9	negative selection	3622546
3004255	3004278	4	-	26780180	A375	viability (Avana lentiGuide)	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.408747020851679	[]	[]	0	hSpCas9	negative selection	3622547
2992244	2992267	4	-	26780180	A375	viability (Avana lentiGuide)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	1.13879675461349	[]	[]	1	hSpCas9	negative selection	3622548
3019688	3019711	4	+	26780180	A375	viability (Avana lentiGuide)	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-3.00550081245866	[]	[]	-5	hSpCas9	negative selection	3622549
2988793	2988816	4	+	26780180	A375	viability (Avana lentiGuide)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	5.75297039705292	[]	[]	5	hSpCas9	negative selection	3622550
3007739	3007762	4	+	26780180	A375	viability (Avana lentiGuide)	TGCCCATAACTACCTAAGAGGGG	GRK4	ENSG00000125388	-2.41128148618277	[]	[]	-4	hSpCas9	negative selection	3622551
2988744	2988767	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.01637947795019007	[6]	[6,5]	0	hSpCas9	positive selection	3731205
3004255	3004278	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.8942407613427604	[4]	[3,0]	-8	hSpCas9	positive selection	3731206
2992244	2992267	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.21691832800832117	[5]	[5,4]	-3	hSpCas9	positive selection	3731207
3019688	3019711	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.12878819894509205	[4]	[4,3]	-2	hSpCas9	positive selection	3731208
2988793	2988816	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.8918422991936827	[5]	[3,1]	-8	hSpCas9	positive selection	3731209
3007739	3007762	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCCCATAACTACCTAAGAGGGG	GRK4	ENSG00000125388	0.13687633855854772	[4]	[4,4]	3	hSpCas9	positive selection	3731210
2988744	2988767	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.3343091066472004	[7]	[8,7]	8	hSpCas9	positive selection	3839812
3004255	3004278	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.6591506688407806	[5]	[4,0]	-7	hSpCas9	positive selection	3839813
2992244	2992267	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.21211640400851967	[6]	[6,5]	5	hSpCas9	positive selection	3839814
3019688	3019711	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.006275518575047517	[4]	[3,4]	0	hSpCas9	positive selection	3839815
2988793	2988816	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.058234762127527435	[4]	[4,3]	1	hSpCas9	positive selection	3839816
3007739	3007762	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCCCATAACTACCTAAGAGGGG	GRK4	ENSG00000125388	0.2445837854141334	[5]	[5,4]	6	hSpCas9	positive selection	3839817
2988793	2988816	4	+	26780180	A375	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.836744681201731	[]	[]	3	hSpCas9	negative selection	3945966
2992220	2992243	4	+	26780180	A375	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.540621441954113	[]	[]	1	hSpCas9	negative selection	3945967
3004258	3004281	4	-	26780180	A375	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.334687311267698	[]	[]	0	hSpCas9	negative selection	3945968
2988744	2988767	4	+	26780180	A375	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.935523763788591	[]	[]	4	hSpCas9	negative selection	3945969
3004316	3004339	4	-	26780180	A375	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.505150412854819	[]	[]	1	hSpCas9	negative selection	3945970
2992244	2992267	4	-	26780180	A375	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	1.12502023974681	[]	[]	5	hSpCas9	negative selection	3945971
2988793	2988816	4	+	26780180	HT29	viability (GeCKOv2 library)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.904821351220304	[]	[]	4	hSpCas9	negative selection	4053932
2992220	2992243	4	+	26780180	HT29	viability (GeCKOv2 library)	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.480318096127044	[]	[]	1	hSpCas9	negative selection	4053933
3004258	3004281	4	-	26780180	HT29	viability (GeCKOv2 library)	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.721762855330557	[]	[]	2	hSpCas9	negative selection	4053934
2988744	2988767	4	+	26780180	HT29	viability (GeCKOv2 library)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.0158664390106629	[]	[]	0	hSpCas9	negative selection	4053935
3004316	3004339	4	-	26780180	HT29	viability (GeCKOv2 library)	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.427297287337395	[]	[]	1	hSpCas9	negative selection	4053936
2992244	2992267	4	-	26780180	HT29	viability (GeCKOv2 library)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.340020027988127	[]	[]	0	hSpCas9	negative selection	4053937
2988793	2988816	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.5862237418338092	[3]	[0,1]	-9	hSpCas9	positive selection	4141233
2992220	2992243	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.005069811481017206	[5]	[3,3]	0	hSpCas9	positive selection	4141234
2992244	2992267	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.018894166624520314	[5]	[3,3]	0	hSpCas9	positive selection	4141235
2988793	2988816	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	1.0467935625080225	[3]	[4,0,1,3]	7	hSpCas9	positive selection	4205255
2992220	2992243	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.2585209027078237	[4]	[0,3,1,0]	-4	hSpCas9	positive selection	4205256
2992244	2992267	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.32259286599835973	[5]	[5,4,4,0]	2	hSpCas9	positive selection	4205257
2988744	2988767	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.115297283637251	[3]	[4,2]	2	hSpCas9	positive selection	4274013
2992220	2992243	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.4790836873835209	[0]	[0,0]	-8	hSpCas9	positive selection	4274014
2988793	2988816	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.21351429932745608	[1]	[2,0]	-4	hSpCas9	positive selection	4274015
3004258	3004281	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.1918814149295781	[3]	[3,2]	4	hSpCas9	positive selection	4338272
3004316	3004339	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2527636550605015	[3]	[4,3]	5	hSpCas9	positive selection	4338273
2992244	2992267	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.040176880118809155	[3]	[4,1]	0	hSpCas9	positive selection	4338274
2988794	2988816	4	+	27760321	OCIAML3	viability	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	1.3579315449321778	[90,64]	[96,229]	9	hSpCas9	negative selection	4405447
3004258	3004280	4	-	27760321	OCIAML3	viability	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.3973665314158602	[200,175]	[201,182]	5	hSpCas9	negative selection	4405448
3004316	3004338	4	-	27760321	OCIAML3	viability	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.5911440558669696	[36,28]	[45,28]	7	hSpCas9	negative selection	4405449
3007738	3007760	4	+	27760321	OCIAML3	viability	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	1.942555685534735	[60,43]	[147,166]	9	hSpCas9	negative selection	4405450
3019793	3019815	4	+	27760321	OCIAML3	viability	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.5389400251795652	[261,214]	[247,297]	6	hSpCas9	negative selection	4405451
2988794	2988816	4	+	27760321	OCIAML2	viability	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	1.0637349624482522	[90,64]	[136,121]	9	hSpCas9	negative selection	4488910
3004258	3004280	4	-	27760321	OCIAML2	viability	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.5484697617537473	[200,175]	[247,188]	7	hSpCas9	negative selection	4488911
3004316	3004338	4	-	27760321	OCIAML2	viability	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.005003942564814956	[36,28]	[20,33]	0	hSpCas9	negative selection	4488912
3007738	3007760	4	+	27760321	OCIAML2	viability	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.8217061637241083	[60,43]	[69,79]	9	hSpCas9	negative selection	4488913
3019793	3019815	4	+	27760321	OCIAML2	viability	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.3564002821525323	[261,214]	[209,292]	5	hSpCas9	negative selection	4488914
2988794	2988816	4	+	27760321	MV411	viability	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.03374411915127418	[90,64]	[0,122]	0	hSpCas9	negative selection	4572373
3004258	3004280	4	-	27760321	MV411	viability	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.9095379081641205	[200,175]	[181,309]	6	hSpCas9	negative selection	4572374
3004316	3004338	4	-	27760321	MV411	viability	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-0.7357314277293727	[36,28]	[0,30]	-5	hSpCas9	negative selection	4572375
3007738	3007760	4	+	27760321	MV411	viability	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.5598340973020068	[60,43]	[0,124]	4	hSpCas9	negative selection	4572376
3019793	3019815	4	+	27760321	MV411	viability	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	-0.375443821497636	[261,214]	[49,226]	-3	hSpCas9	negative selection	4572377
2988794	2988816	4	+	27760321	HL60	viability	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.742391094354728	[90,64]	[43,30]	-6	hSpCas9	negative selection	4655836
3004258	3004280	4	-	27760321	HL60	viability	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	-0.24033659328608037	[200,175]	[148,109]	-3	hSpCas9	negative selection	4655837
3004316	3004338	4	-	27760321	HL60	viability	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	1.0927041862403288	[36,28]	[10,105]	9	hSpCas9	negative selection	4655838
3007738	3007760	4	+	27760321	HL60	viability	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	1.0721392375740653	[60,43]	[64,114]	9	hSpCas9	negative selection	4655839
3019793	3019815	4	+	27760321	HL60	viability	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.14175695499991614	[261,214]	[243,181]	1	hSpCas9	negative selection	4655840
2988794	2988816	4	+	27760321	HT1080	viability	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-2.2218389643172847	[64,50]	[3,5]	-6	hSpCas9	negative selection	4739299
3004258	3004280	4	-	27760321	HT1080	viability	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.8987147920696181	[175,137]	[87,147]	5	hSpCas9	negative selection	4739300
3004316	3004338	4	-	27760321	HT1080	viability	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-3.3740579379166626	[28,22]	[0,0]	-7	hSpCas9	negative selection	4739301
3007738	3007760	4	+	27760321	HT1080	viability	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.7907513416959202	[43,34]	[0,55]	4	hSpCas9	negative selection	4739302
3019793	3019815	4	+	27760321	HT1080	viability	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	1.3223587797897103	[214,167]	[80,310]	7	hSpCas9	negative selection	4739303
2988794	2988816	4	+	27760321	HT29	viability after 7 days	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.8655512075164862	[64,50]	[244,165,15]	9	hSpCas9	negative selection	4822762
3004258	3004280	4	-	27760321	HT29	viability after 7 days	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.3893332994070151	[175,137]	[315,271,213]	6	hSpCas9	negative selection	4822763
3004316	3004338	4	-	27760321	HT29	viability after 7 days	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-0.1800857537584979	[28,22]	[17,41,26]	-3	hSpCas9	negative selection	4822764
3007738	3007760	4	+	27760321	HT29	viability after 7 days	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.5665309869831585	[43,34]	[141,71,22]	8	hSpCas9	negative selection	4822765
3019793	3019815	4	+	27760321	HT29	viability after 7 days	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.4218107931682602	[214,167]	[507,192,313]	6	hSpCas9	negative selection	4822766
2988794	2988816	4	+	27760321	HT29	viability after 25 days	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.9725991441213546	[64,50]	[94,178,116]	9	hSpCas9	negative selection	4906225
3004258	3004280	4	-	27760321	HT29	viability after 25 days	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	-0.21927573851972282	[175,137]	[57,258,150]	-2	hSpCas9	negative selection	4906226
3004316	3004338	4	-	27760321	HT29	viability after 25 days	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.7560953933688745	[28,22]	[4,41,112]	8	hSpCas9	negative selection	4906227
3007738	3007760	4	+	27760321	HT29	viability after 25 days	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	1.7566679454887146	[43,34]	[171,51,241]	9	hSpCas9	negative selection	4906228
3019793	3019815	4	+	27760321	HT29	viability after 25 days	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.40944482458629927	[214,167]	[280,138,470]	4	hSpCas9	negative selection	4906229
2988794	2988816	4	+	27760321	HT29	viability after 22 days	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	1.3360908557034268	[64,50]	[125,231,150]	9	hSpCas9	negative selection	4989688
3004258	3004280	4	-	27760321	HT29	viability after 22 days	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	-0.052281647946424314	[175,137]	[130,267,126]	0	hSpCas9	negative selection	4989689
3004316	3004338	4	-	27760321	HT29	viability after 22 days	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-0.07951458207102613	[28,22]	[2,65,16]	-1	hSpCas9	negative selection	4989690
3007738	3007760	4	+	27760321	HT29	viability after 22 days	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	1.0343701898013369	[43,34]	[29,120,131]	9	hSpCas9	negative selection	4989691
3019793	3019815	4	+	27760321	HT29	viability after 22 days	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.43495065770689606	[214,167]	[190,182,528]	5	hSpCas9	negative selection	4989692
2988794	2988816	4	+	27760321	HT29	viability after 19 days	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	1.7942948744366949	[64,50]	[103,152,412]	9	hSpCas9	negative selection	5073151
3004258	3004280	4	-	27760321	HT29	viability after 19 days	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.09851569629402612	[175,137]	[228,249,104]	0	hSpCas9	negative selection	5073152
3004316	3004338	4	-	27760321	HT29	viability after 19 days	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.7141115468309098	[28,22]	[56,59,30]	7	hSpCas9	negative selection	5073153
3007738	3007760	4	+	27760321	HT29	viability after 19 days	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	1.4166780516796593	[43,34]	[139,71,150]	9	hSpCas9	negative selection	5073154
3019793	3019815	4	+	27760321	HT29	viability after 19 days	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.8393405598817314	[214,167]	[349,320,495]	8	hSpCas9	negative selection	5073155
2988794	2988816	4	+	27760321	HT29	viability after 16 days	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.7187957998065748	[64,50]	[125,117,77]	8	hSpCas9	negative selection	5156614
3004258	3004280	4	-	27760321	HT29	viability after 16 days	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.528872273991262	[175,137]	[189,194,370]	6	hSpCas9	negative selection	5156615
3004316	3004338	4	-	27760321	HT29	viability after 16 days	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.7124382636904554	[28,22]	[1,116,17]	8	hSpCas9	negative selection	5156616
3007738	3007760	4	+	27760321	HT29	viability after 16 days	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	1.0697086548121817	[43,34]	[82,79,114]	9	hSpCas9	negative selection	5156617
3019793	3019815	4	+	27760321	HT29	viability after 16 days	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.7178244781009478	[214,167]	[390,229,442]	8	hSpCas9	negative selection	5156618
2988794	2988816	4	+	27760321	HT29	viability after 13 days	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.5138642427628093	[64,50]	[66,152,69]	6	hSpCas9	negative selection	5240077
3004258	3004280	4	-	27760321	HT29	viability after 13 days	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.5649412775803068	[175,137]	[307,257,243]	7	hSpCas9	negative selection	5240078
3004316	3004338	4	-	27760321	HT29	viability after 13 days	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	1.5818168355388171	[28,22]	[47,128,93]	9	hSpCas9	negative selection	5240079
3007738	3007760	4	+	27760321	HT29	viability after 13 days	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	1.1488367686226293	[43,34]	[136,81,86]	9	hSpCas9	negative selection	5240080
3019793	3019815	4	+	27760321	HT29	viability after 13 days	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.2631833235863912	[214,167]	[361,142,292]	3	hSpCas9	negative selection	5240081
2988794	2988816	4	+	27760321	HT29	viability after 10 days	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.36482770977730716	[64,50]	[96,114,68]	5	hSpCas9	negative selection	5323540
3004258	3004280	4	-	27760321	HT29	viability after 10 days	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.7267767207187432	[175,137]	[154,651,178]	8	hSpCas9	negative selection	5323541
3004316	3004338	4	-	27760321	HT29	viability after 10 days	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	1.6168549134338654	[28,22]	[34,68,191]	9	hSpCas9	negative selection	5323542
3007738	3007760	4	+	27760321	HT29	viability after 10 days	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	0.5560552712149831	[43,34]	[25,97,93]	7	hSpCas9	negative selection	5323543
3019793	3019815	4	+	27760321	HT29	viability after 10 days	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.8181429108448498	[214,167]	[564,262,431]	9	hSpCas9	negative selection	5323544
2988794	2988816	4	+	27760321	MOLM13	viability	TACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	1.2972304889302513	[90,64]	[220,9]	8	hSpCas9	negative selection	5407003
3004258	3004280	4	-	27760321	MOLM13	viability	TACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	1.069227243626816	[200,175]	[105,321]	7	hSpCas9	negative selection	5407004
3004316	3004338	4	-	27760321	MOLM13	viability	TACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-1.2050318102884323	[36,28]	[0,13]	-6	hSpCas9	negative selection	5407005
3007738	3007760	4	+	27760321	MOLM13	viability	TTGCCCATAACTACCTAAGAGG	GRK4	ENSG00000125388	-4.874001469911928	[60,43]	[0,0]	-9	hSpCas9	negative selection	5407006
3019793	3019815	4	+	27760321	MOLM13	viability	CGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.46789367695815026	[261,214]	[336,55]	3	hSpCas9	negative selection	5407007
2963971	2963994	4	+	27661255	K562	viability	GCCCGGCGAGCTATGCACGGGGG	GRK4	ENSG00000125388	-0.3180987029018446	[494,415]	[349,243]	-7	dCas9-KRAB	negative selection	5483437
2964033	2964056	4	+	27661255	K562	viability	GGTCTCGCAGAATCCGCCGGCGG	GRK4	ENSG00000125388	0.03456050417907151	[777,841]	[691,635]	1	dCas9-KRAB	negative selection	5483438
2964052	2964075	4	+	27661255	K562	viability	GCGGCGGCGGCGCCAGGACATGG	GRK4	ENSG00000125388	0.22985189608463186	[126,174]	[131,147]	7	dCas9-KRAB	negative selection	5483439
2963633	2963656	4	-	27661255	K562	viability	GCCGGCGACCCGCTCCCGGGCGG	GRK4	ENSG00000125388	0.01907956023069879	[669,540]	[579,416]	0	dCas9-KRAB	negative selection	5483440
2963636	2963659	4	-	27661255	K562	viability	GCGGCCGGCGACCCGCTCCCGGG	GRK4	ENSG00000125388	0.34038320534922745	[477,496]	[523,465]	9	dCas9-KRAB	negative selection	5483441
2964005	2964028	4	-	27661255	K562	viability	GACTGAGGAGGCGGAACAGGAGG	GRK4	ENSG00000125388	0.175252855008442	[419,636]	[497,451]	6	dCas9-KRAB	negative selection	5483442
2988744	2988767	4	+	27260156	BXPC3	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.00878850169072154	[920]	[736,969,938,1232]	0	hSpCas9	negative selection	5546473
2992220	2992243	4	+	27260156	BXPC3	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.3115235446088227	[55]	[70,89,87,35]	6	hSpCas9	negative selection	5546474
2988793	2988816	4	+	27260156	BXPC3	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.14504726924157452	[182]	[170,162,167,191]	-3	hSpCas9	negative selection	5546475
3004258	3004281	4	-	27260156	BXPC3	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.25524401530138996	[679]	[727,734,1050,904]	5	hSpCas9	negative selection	5610732
3004316	3004339	4	-	27260156	BXPC3	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.09739686903588374	[970]	[1082,964,1135,1171]	2	hSpCas9	negative selection	5610733
2992244	2992267	4	-	27260156	BXPC3	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.003729513064820833	[787]	[696,852,860,910]	0	hSpCas9	negative selection	5610734
2988744	2988767	4	+	27260156	A673	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.028862988120123556	[920]	[1349,1040,997,1151]	0	hSpCas9	negative selection	5667724
2992220	2992243	4	+	27260156	A673	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.07166247539883575	[55]	[121,57,53,53]	1	hSpCas9	negative selection	5667725
2988793	2988816	4	+	27260156	A673	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.21073345701097512	[182]	[196,175,185,201]	-5	hSpCas9	negative selection	5667726
3004258	3004281	4	-	27260156	A673	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.24309491174052567	[679]	[927,839,934,1170]	6	hSpCas9	negative selection	5731983
3004316	3004339	4	-	27260156	A673	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2537025975046756	[970]	[1392,1207,1437,1530]	6	hSpCas9	negative selection	5731984
2992244	2992267	4	-	27260156	A673	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.11241831484898857	[787]	[1112,970,999,1016]	2	hSpCas9	negative selection	5731985
2988744	2988767	4	+	27260156	A375	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.27333905164059613	[920]	[1262,1636,1143,1208]	4	hSpCas9	negative selection	5788975
2992220	2992243	4	+	27260156	A375	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-1.9737278607847237	[55]	[41,12,10,1]	-9	hSpCas9	negative selection	5788976
2988793	2988816	4	+	27260156	A375	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.34588649001230465	[182]	[120,226,173,158]	-5	hSpCas9	negative selection	5788977
3004258	3004281	4	-	27260156	A375	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.42923456661338744	[679]	[1281,1313,983,765]	6	hSpCas9	negative selection	5853234
3004316	3004339	4	-	27260156	A375	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.41542869747083144	[970]	[1138,2386,1362,1299]	6	hSpCas9	negative selection	5853235
2992244	2992267	4	-	27260156	A375	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.08393002753385204	[787]	[878,1020,918,1072]	1	hSpCas9	negative selection	5853236
2988744	2988767	4	+	27260156	COLO741	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.062260391400293824	[920]	[1281,1376,1042]	1	hSpCas9	negative selection	5910226
2992220	2992243	4	+	27260156	COLO741	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.9548892239264628	[55]	[15,70,22]	-9	hSpCas9	negative selection	5910227
2988793	2988816	4	+	27260156	COLO741	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.04853264377835065	[182]	[242,239,241]	1	hSpCas9	negative selection	5910228
3004258	3004281	4	-	27260156	COLO741	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.1874113350123735	[679]	[969,1028,966]	4	hSpCas9	negative selection	5974485
3004316	3004339	4	-	27260156	COLO741	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.25392450057601046	[970]	[1599,1380,1464]	5	hSpCas9	negative selection	5974486
2992244	2992267	4	-	27260156	COLO741	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.038505387627883136	[787]	[1095,797,1048]	-1	hSpCas9	negative selection	5974487
2988744	2988767	4	+	27260156	CAL120	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.3830040103560989	[920]	[2376,922,1318]	6	hSpCas9	negative selection	6031477
2992220	2992243	4	+	27260156	CAL120	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.030457614271629296	[55]	[3,66,122]	0	hSpCas9	negative selection	6031478
2988793	2988816	4	+	27260156	CAL120	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.06937398637381542	[182]	[209,169,268]	-1	hSpCas9	negative selection	6031479
3004258	3004281	4	-	27260156	CAL120	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.20219003568855354	[679]	[1257,850,855]	3	hSpCas9	negative selection	6095736
3004316	3004339	4	-	27260156	CAL120	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.337387219497127	[970]	[2068,1405,1191]	5	hSpCas9	negative selection	6095737
2992244	2992267	4	-	27260156	CAL120	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.08212630829083445	[787]	[1006,873,909]	-1	hSpCas9	negative selection	6095738
2988744	2988767	4	+	27260156	CADOES1	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.08793205317161057	[920]	[669,914,891,744]	-1	hSpCas9	negative selection	6152728
2992220	2992243	4	+	27260156	CADOES1	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.77674726802034	[55]	[145,91,100,14]	9	hSpCas9	negative selection	6152729
2988793	2988816	4	+	27260156	CADOES1	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.19423862600466957	[182]	[178,98,189,125]	-3	hSpCas9	negative selection	6152730
3004258	3004281	4	-	27260156	CADOES1	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.5074385147070193	[679]	[833,914,853,996]	8	hSpCas9	negative selection	6216987
3004316	3004339	4	-	27260156	CADOES1	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2676276373558839	[970]	[1172,1044,949,1183]	4	hSpCas9	negative selection	6216988
2992244	2992267	4	-	27260156	CADOES1	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.1502944232724467	[787]	[901,515,679,537]	-3	hSpCas9	negative selection	6216989
2988744	2988767	4	+	27260156	EWS502	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.13978446826371826	[920]	[898,1274,958,1180]	2	hSpCas9	negative selection	6273979
2992220	2992243	4	+	27260156	EWS502	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-1.8184229092262711	[55]	[11,38,8,5]	-9	hSpCas9	negative selection	6273980
2988793	2988816	4	+	27260156	EWS502	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.25031134798541754	[182]	[143,227,117,159]	-4	hSpCas9	negative selection	6273981
3004258	3004281	4	-	27260156	EWS502	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.21010745005705034	[679]	[672,945,957,763]	3	hSpCas9	negative selection	6338238
3004316	3004339	4	-	27260156	EWS502	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.08888065095996911	[970]	[1239,790,1028,1320]	1	hSpCas9	negative selection	6338239
2992244	2992267	4	-	27260156	EWS502	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.35891039830007443	[787]	[1168,1258,1016,791]	6	hSpCas9	negative selection	6338240
2988744	2988767	4	+	27260156	EW8	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.11025430506951961	[920]	[911,834,790,696]	2	hSpCas9	negative selection	6395230
2992220	2992243	4	+	27260156	EW8	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-2.519628827959541	[55]	[18,2,6,3]	-9	hSpCas9	negative selection	6395231
2988793	2988816	4	+	27260156	EW8	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.2137775472121215	[182]	[297,124,131,152]	4	hSpCas9	negative selection	6395232
3004258	3004281	4	-	27260156	EW8	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.15888066078087182	[679]	[636,788,458,603]	3	hSpCas9	negative selection	6459489
3004316	3004339	4	-	27260156	EW8	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2140159982950951	[970]	[943,1086,757,889]	4	hSpCas9	negative selection	6459490
2992244	2992267	4	-	27260156	EW8	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.1562994327398931	[787]	[817,613,584,859]	3	hSpCas9	negative selection	6459491
2988744	2988767	4	+	27260156	CORL105	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.03326789310378697	[920]	[1266,911,1207,1051]	0	hSpCas9	negative selection	6516481
2992220	2992243	4	+	27260156	CORL105	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.8274515276908332	[55]	[51,43,22,26]	-8	hSpCas9	negative selection	6516482
2988793	2988816	4	+	27260156	CORL105	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.4347372248373317	[182]	[332,240,266,315]	7	hSpCas9	negative selection	6516483
3004258	3004281	4	-	27260156	CORL105	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.1671226935179334	[679]	[866,808,1041,880]	3	hSpCas9	negative selection	6580740
3004316	3004339	4	-	27260156	CORL105	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.20301997554449502	[970]	[1232,1120,1648,1284]	4	hSpCas9	negative selection	6580741
2992244	2992267	4	-	27260156	CORL105	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.12216952591251395	[787]	[726,773,1043,872]	-2	hSpCas9	negative selection	6580742
2988744	2988767	4	+	27260156	HS294T	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.25907416092293445	[920]	[367,343,361,679]	3	hSpCas9	negative selection	6637732
2992220	2992243	4	+	27260156	HS294T	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.8271170146492235	[55]	[13,18,4,9]	-8	hSpCas9	negative selection	6637733
2988793	2988816	4	+	27260156	HS294T	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.42278693995251615	[182]	[22,73,73,39]	-6	hSpCas9	negative selection	6637734
3004258	3004281	4	-	27260156	HS294T	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.6490465564409313	[679]	[429,441,400,363]	8	hSpCas9	negative selection	6701991
3004316	3004339	4	-	27260156	HS294T	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-0.3027007557957685	[970]	[305,321,291,293]	-4	hSpCas9	negative selection	6701992
2992244	2992267	4	-	27260156	HS294T	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.124151279368234	[787]	[185,259,306,392]	-2	hSpCas9	negative selection	6701993
2988744	2988767	4	+	27260156	HCC44	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.033528427629303637	[920]	[1144,721,1206,1255]	0	hSpCas9	negative selection	6758983
2992220	2992243	4	+	27260156	HCC44	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.492526581479503	[55]	[20,21,103,43]	-6	hSpCas9	negative selection	6758984
2988793	2988816	4	+	27260156	HCC44	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.3978825555185663	[182]	[101,118,214,199]	-6	hSpCas9	negative selection	6758985
3004258	3004281	4	-	27260156	HCC44	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.33616179669114166	[679]	[1091,842,1136,864]	5	hSpCas9	negative selection	6823242
3004316	3004339	4	-	27260156	HCC44	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.08578795880071666	[970]	[1195,1022,1524,998]	1	hSpCas9	negative selection	6823243
2992244	2992267	4	-	27260156	HCC44	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.004156978129068123	[787]	[886,638,1165,936]	0	hSpCas9	negative selection	6823244
2988744	2988767	4	+	27260156	G402	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.2428700084081542	[920]	[1500,1507,1639,729]	3	hSpCas9	negative selection	6880234
2992220	2992243	4	+	27260156	G402	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.13635614501711002	[55]	[59,53,49,129]	1	hSpCas9	negative selection	6880235
2988793	2988816	4	+	27260156	G402	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.25626352495574944	[182]	[113,184,240,195]	-3	hSpCas9	negative selection	6880236
3004258	3004281	4	-	27260156	G402	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.4653903854311041	[679]	[924,1000,1471,1139]	6	hSpCas9	negative selection	6944493
3004316	3004339	4	-	27260156	G402	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.3781071597558294	[970]	[1630,2014,1005,1541]	5	hSpCas9	negative selection	6944494
2992244	2992267	4	-	27260156	G402	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.24183789399564626	[787]	[785,820,1230,426]	-3	hSpCas9	negative selection	6944495
2988744	2988767	4	+	27260156	L33	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.22847666163476055	[920]	[1049,572,507,1058]	5	hSpCas9	negative selection	7001485
2992220	2992243	4	+	27260156	L33	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.2642961868323912	[55]	[31,12,31,71]	-6	hSpCas9	negative selection	7001486
2988793	2988816	4	+	27260156	L33	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.23638465267420283	[182]	[211,57,81,135]	-5	hSpCas9	negative selection	7001487
3004258	3004281	4	-	27260156	L33	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.1368854325921144	[679]	[948,306,419,619]	3	hSpCas9	negative selection	7065744
3004316	3004339	4	-	27260156	L33	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	-0.09905289976731746	[970]	[928,380,603,806]	-2	hSpCas9	negative selection	7065745
2992244	2992267	4	-	27260156	L33	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.13763528467108155	[787]	[803,342,586,893]	3	hSpCas9	negative selection	7065746
2988744	2988767	4	+	27260156	K562	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.10559638055253073	[920]	[1011,984,934,627]	1	hSpCas9	negative selection	7122736
2992220	2992243	4	+	27260156	K562	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.7148767885803875	[55]	[19,5,44,45]	-7	hSpCas9	negative selection	7122737
2988793	2988816	4	+	27260156	K562	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.4686558310786255	[182]	[89,36,109,213]	-5	hSpCas9	negative selection	7122738
3004258	3004281	4	-	27260156	K562	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.0491963314574112	[679]	[493,434,927,617]	0	hSpCas9	negative selection	7186995
3004316	3004339	4	-	27260156	K562	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.03523108667489372	[970]	[805,755,1152,808]	0	hSpCas9	negative selection	7186996
2992244	2992267	4	-	27260156	K562	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.04783150369108147	[787]	[1053,485,752,621]	0	hSpCas9	negative selection	7186997
2988744	2988767	4	+	27260156	HT29	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.3249597097962028	[920]	[1329,1393,1330,1522]	6	hSpCas9	negative selection	7243987
2992220	2992243	4	+	27260156	HT29	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.0033313239646912685	[55]	[72,88,75,38]	0	hSpCas9	negative selection	7243988
2988793	2988816	4	+	27260156	HT29	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.2939492919190796	[182]	[269,307,332,190]	6	hSpCas9	negative selection	7243989
3004258	3004281	4	-	27260156	HT29	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.3059671895454473	[679]	[1089,1156,962,901]	6	hSpCas9	negative selection	7308246
3004316	3004339	4	-	27260156	HT29	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.34803427984000046	[970]	[1613,1714,1342,1369]	6	hSpCas9	negative selection	7308247
2992244	2992267	4	-	27260156	HT29	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.077486615242496	[787]	[794,1436,878,951]	1	hSpCas9	negative selection	7308248
2988744	2988767	4	+	27260156	MHHES1	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.12389530726111897	[920]	[1157,1326,1029,1026]	2	hSpCas9	negative selection	7365238
2992220	2992243	4	+	27260156	MHHES1	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.5910998187646594	[55]	[65,29,64,13]	-8	hSpCas9	negative selection	7365239
2988793	2988816	4	+	27260156	MHHES1	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.22681996622945122	[182]	[229,155,103,206]	-4	hSpCas9	negative selection	7365240
3004258	3004281	4	-	27260156	MHHES1	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.3307438332233025	[679]	[895,922,967,1017]	6	hSpCas9	negative selection	7429497
3004316	3004339	4	-	27260156	MHHES1	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.22379309731403652	[970]	[1248,1266,1517,1086]	4	hSpCas9	negative selection	7429498
2992244	2992267	4	-	27260156	MHHES1	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.0761000193580057	[787]	[883,1160,495,841]	-1	hSpCas9	negative selection	7429499
2988744	2988767	4	+	27260156	MEWO	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.07065977380434085	[920]	[967,779,741]	-1	hSpCas9	negative selection	7486489
2992220	2992243	4	+	27260156	MEWO	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.20265783066652965	[55]	[103,23,19]	-4	hSpCas9	negative selection	7486490
2988793	2988816	4	+	27260156	MEWO	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.10998022596068302	[182]	[137,135,197]	-2	hSpCas9	negative selection	7486491
3004258	3004281	4	-	27260156	MEWO	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.2826476961507498	[679]	[1071,607,699]	6	hSpCas9	negative selection	7550748
3004316	3004339	4	-	27260156	MEWO	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2821031613544187	[970]	[988,1148,1152]	6	hSpCas9	negative selection	7550749
2992244	2992267	4	-	27260156	MEWO	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.1097138214689184	[787]	[793,786,804]	2	hSpCas9	negative selection	7550750
2988744	2988767	4	+	27260156	LNCAPCLONEFGC	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.0929297365823677	[920]	[1019,874,902,760]	1	hSpCas9	negative selection	7607740
2992220	2992243	4	+	27260156	LNCAPCLONEFGC	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-1.2699443109328534	[55]	[38,1,40,5]	-9	hSpCas9	negative selection	7607741
2988793	2988816	4	+	27260156	LNCAPCLONEFGC	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.12781816780351174	[182]	[212,143,246,131]	2	hSpCas9	negative selection	7607742
3004258	3004281	4	-	27260156	LNCAPCLONEFGC	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.4183165778510316	[679]	[891,715,897,802]	6	hSpCas9	negative selection	7671999
3004316	3004339	4	-	27260156	LNCAPCLONEFGC	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.08278150657883598	[970]	[928,870,1001,937]	1	hSpCas9	negative selection	7672000
2992244	2992267	4	-	27260156	LNCAPCLONEFGC	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.03878764869333129	[787]	[696,760,811,521]	0	hSpCas9	negative selection	7672001
2988744	2988767	4	+	27260156	PANC0327	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.0775935239327975	[920]	[774,1035,1016,595]	1	hSpCas9	negative selection	7728991
2992220	2992243	4	+	27260156	PANC0327	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.8677678591376017	[55]	[72,1,4,35]	-8	hSpCas9	negative selection	7728992
2988793	2988816	4	+	27260156	PANC0327	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.2935802782243391	[182]	[119,167,177,58]	-4	hSpCas9	negative selection	7728993
3004258	3004281	4	-	27260156	PANC0327	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.34719745484797115	[679]	[874,573,709,947]	5	hSpCas9	negative selection	7793250
3004316	3004339	4	-	27260156	PANC0327	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.08298894850871852	[970]	[1172,662,578,1291]	1	hSpCas9	negative selection	7793251
2992244	2992267	4	-	27260156	PANC0327	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.17415754400030947	[787]	[946,578,790,881]	2	hSpCas9	negative selection	7793252
2988744	2988767	4	+	27260156	NCIH2009	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.48809636648056454	[920]	[2125,1303,2053]	6	hSpCas9	negative selection	7850242
2992220	2992243	4	+	27260156	NCIH2009	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.4648215201594663	[55]	[107,7,64]	-6	hSpCas9	negative selection	7850243
2988793	2988816	4	+	27260156	NCIH2009	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.32333864803903034	[182]	[196,106,308]	-4	hSpCas9	negative selection	7850244
3004258	3004281	4	-	27260156	NCIH2009	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.5581308841062358	[679]	[1526,1314,1378]	7	hSpCas9	negative selection	7914501
3004316	3004339	4	-	27260156	NCIH2009	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2489582015043874	[970]	[1672,1323,1853]	3	hSpCas9	negative selection	7914502
2992244	2992267	4	-	27260156	NCIH2009	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.18798278532584034	[787]	[1202,1049,1500]	2	hSpCas9	negative selection	7914503
2988744	2988767	4	+	27260156	NCIH1373	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.22264802344376677	[920]	[1490,1157,964,329]	2	hSpCas9	negative selection	7971493
2992220	2992243	4	+	27260156	NCIH1373	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	1.0354854090213337	[55]	[170,203,111,4]	9	hSpCas9	negative selection	7971494
2988793	2988816	4	+	27260156	NCIH1373	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.41211229905140234	[182]	[218,190,78,34]	-4	hSpCas9	negative selection	7971495
3004258	3004281	4	-	27260156	NCIH1373	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.6486224416083666	[679]	[1338,1144,706,432]	6	hSpCas9	negative selection	8035752
3004316	3004339	4	-	27260156	NCIH1373	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.4093009279111335	[970]	[1742,1323,1413,353]	4	hSpCas9	negative selection	8035753
2992244	2992267	4	-	27260156	NCIH1373	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.213540337945332	[787]	[1277,861,813,317]	2	hSpCas9	negative selection	8035754
2988744	2988767	4	+	27260156	PATU8902	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.1877824745589598	[920]	[1241,1502,814,1000]	-2	hSpCas9	negative selection	8092744
2992220	2992243	4	+	27260156	PATU8902	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.36879658338822763	[55]	[50,21,5,191]	-4	hSpCas9	negative selection	8092745
2988793	2988816	4	+	27260156	PATU8902	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.09043363625071321	[182]	[334,159,70,457]	-1	hSpCas9	negative selection	8092746
3004258	3004281	4	-	27260156	PATU8902	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.3816150682310071	[679]	[1062,1302,747,2035]	4	hSpCas9	negative selection	8157003
3004316	3004339	4	-	27260156	PATU8902	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.8255091727478556	[970]	[3513,1929,2041,2123]	8	hSpCas9	negative selection	8157004
2992244	2992267	4	-	27260156	PATU8902	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.3861346827244633	[787]	[1730,1634,1047,1404]	4	hSpCas9	negative selection	8157005
2988744	2988767	4	+	27260156	PANC1	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.07620134399534473	[920]	[640,911,1034,766]	1	hSpCas9	negative selection	8213995
2992220	2992243	4	+	27260156	PANC1	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.5316752424360502	[55]	[88,10,16,12]	-7	hSpCas9	negative selection	8213996
2988793	2988816	4	+	27260156	PANC1	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.3361879176465439	[182]	[120,162,136,88]	-5	hSpCas9	negative selection	8213997
3004258	3004281	4	-	27260156	PANC1	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.4241583466617802	[679]	[877,840,561,838]	7	hSpCas9	negative selection	8278254
3004316	3004339	4	-	27260156	PANC1	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2480374974158337	[970]	[950,1364,848,875]	4	hSpCas9	negative selection	8278255
2992244	2992267	4	-	27260156	PANC1	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.007111705634440191	[787]	[716,855,615,572]	0	hSpCas9	negative selection	8278256
2988744	2988767	4	+	27260156	PANC0813	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.3579245411006443	[920]	[1469,1304,1640,1149]	6	hSpCas9	negative selection	8335246
2992220	2992243	4	+	27260156	PANC0813	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.6389525960687261	[55]	[79,86,40,193]	8	hSpCas9	negative selection	8335247
2988793	2988816	4	+	27260156	PANC0813	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.06449185362407439	[182]	[290,147,120,265]	-1	hSpCas9	negative selection	8335248
3004258	3004281	4	-	27260156	PANC0813	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.43505587421457725	[679]	[1071,913,1063,1256]	7	hSpCas9	negative selection	8399505
3004316	3004339	4	-	27260156	PANC0813	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.23813685593348421	[970]	[1455,1382,1248,1302]	4	hSpCas9	negative selection	8399506
2992244	2992267	4	-	27260156	PANC0813	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.24895764110299762	[787]	[983,774,655,720]	-4	hSpCas9	negative selection	8399507
2988744	2988767	4	+	27260156	RDES	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.06195365754906623	[920]	[888,818,1227,1168]	-1	hSpCas9	negative selection	8456497
2992220	2992243	4	+	27260156	RDES	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-1.2338680487268583	[55]	[7,26,8,75]	-9	hSpCas9	negative selection	8456498
2988793	2988816	4	+	27260156	RDES	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.19972001187752708	[182]	[118,197,275,144]	-3	hSpCas9	negative selection	8456499
3004258	3004281	4	-	27260156	RDES	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.34178481736836763	[679]	[927,758,1033,1295]	5	hSpCas9	negative selection	8520756
3004316	3004339	4	-	27260156	RDES	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.04551867434508616	[970]	[1052,1090,1026,1472]	0	hSpCas9	negative selection	8520757
2992244	2992267	4	-	27260156	RDES	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.215974298654377	[787]	[873,825,1133,1472]	3	hSpCas9	negative selection	8520758
2988744	2988767	4	+	27260156	PC3	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.08334618759712609	[920]	[566,791,1511,895]	-2	hSpCas9	negative selection	8577748
2992220	2992243	4	+	27260156	PC3	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.5842966136700896	[55]	[1,32,46,87]	-8	hSpCas9	negative selection	8577749
2988793	2988816	4	+	27260156	PC3	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.0025240462683830955	[182]	[125,185,392,109]	0	hSpCas9	negative selection	8577750
3004258	3004281	4	-	27260156	PC3	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.32155403356820844	[679]	[472,892,1508,857]	7	hSpCas9	negative selection	8642007
3004316	3004339	4	-	27260156	PC3	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.35289563131313306	[970]	[797,1412,1943,1115]	7	hSpCas9	negative selection	8642008
2992244	2992267	4	-	27260156	PC3	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.061116471591028954	[787]	[494,633,1286,851]	-1	hSpCas9	negative selection	8642009
2988744	2988767	4	+	27260156	PATU8988T	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.07362752902780267	[920]	[1087,789,884,972]	1	hSpCas9	negative selection	8698999
2992220	2992243	4	+	27260156	PATU8988T	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.623287840180633	[55]	[9,94,82,151]	8	hSpCas9	negative selection	8699000
2988793	2988816	4	+	27260156	PATU8988T	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.28721364340542177	[182]	[230,203,250,171]	5	hSpCas9	negative selection	8699001
3004258	3004281	4	-	27260156	PATU8988T	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.3172131190244373	[679]	[878,1173,568,677]	5	hSpCas9	negative selection	8763258
3004316	3004339	4	-	27260156	PATU8988T	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.30684050900102	[970]	[1177,1063,1330,1048]	5	hSpCas9	negative selection	8763259
2992244	2992267	4	-	27260156	PATU8988T	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.21584450954355272	[787]	[748,1182,847,776]	4	hSpCas9	negative selection	8763260
2988744	2988767	4	+	27260156	T47D	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.024554872860976462	[920]	[1132,974,944,1178]	0	hSpCas9	negative selection	8820250
2992220	2992243	4	+	27260156	T47D	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.4679488348737073	[55]	[46,30,39,72]	-7	hSpCas9	negative selection	8820251
2988793	2988816	4	+	27260156	T47D	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.1971774602360119	[182]	[189,156,169,230]	-4	hSpCas9	negative selection	8820252
3004258	3004281	4	-	27260156	T47D	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.2443962010526547	[679]	[984,922,794,1057]	5	hSpCas9	negative selection	8884509
3004316	3004339	4	-	27260156	T47D	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.3913830541920036	[970]	[1457,1328,1629,1529]	8	hSpCas9	negative selection	8884510
2992244	2992267	4	-	27260156	T47D	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.09686161775761282	[787]	[1072,647,858,872]	-2	hSpCas9	negative selection	8884511
2988744	2988767	4	+	27260156	SU8686	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.23563527182141664	[920]	[1252,962,1044,1014]	4	hSpCas9	negative selection	8941501
2992220	2992243	4	+	27260156	SU8686	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.2495547017162667	[55]	[31,42,18,102]	-4	hSpCas9	negative selection	8941502
2988793	2988816	4	+	27260156	SU8686	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.2846856126627355	[182]	[201,131,128,122]	-5	hSpCas9	negative selection	8941503
3004258	3004281	4	-	27260156	SU8686	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.5306087675445756	[679]	[892,737,1054,1296]	8	hSpCas9	negative selection	9005760
3004316	3004339	4	-	27260156	SU8686	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.0877584664525608	[970]	[797,899,1007,1496]	1	hSpCas9	negative selection	9005761
2992244	2992267	4	-	27260156	SU8686	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.02666576076711802	[787]	[701,693,831,1008]	0	hSpCas9	negative selection	9005762
2988744	2988767	4	+	27260156	SKES1	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.017182250134847754	[920]	[1080,1060,872,752]	0	hSpCas9	negative selection	9062752
2992220	2992243	4	+	27260156	SKES1	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	0.3324511390185463	[55]	[59,140,12,73]	7	hSpCas9	negative selection	9062753
2988793	2988816	4	+	27260156	SKES1	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.18594260904918203	[182]	[148,159,174,154]	-4	hSpCas9	negative selection	9062754
3004258	3004281	4	-	27260156	SKES1	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.29948984470141793	[679]	[841,819,888,783]	6	hSpCas9	negative selection	9127011
3004316	3004339	4	-	27260156	SKES1	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.22781129675387035	[970]	[1239,1217,1051,1050]	5	hSpCas9	negative selection	9127012
2992244	2992267	4	-	27260156	SKES1	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.040980154387871726	[787]	[850,884,585,755]	-1	hSpCas9	negative selection	9127013
2988744	2988767	4	+	27260156	TOV112D	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	0.12298224932418023	[920]	[852,1187,1047,960]	2	hSpCas9	negative selection	9184003
2992220	2992243	4	+	27260156	TOV112D	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.5700537714509868	[55]	[31,57,7,56]	-8	hSpCas9	negative selection	9184004
2988793	2988816	4	+	27260156	TOV112D	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.4577276028296855	[182]	[82,136,204,105]	-7	hSpCas9	negative selection	9184005
3004258	3004281	4	-	27260156	TOV112D	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.38141392954086295	[679]	[836,1068,733,945]	7	hSpCas9	negative selection	9248262
3004316	3004339	4	-	27260156	TOV112D	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.19721335628419578	[970]	[1475,1285,780,990]	4	hSpCas9	negative selection	9248263
2992244	2992267	4	-	27260156	TOV112D	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	-0.17543883959989637	[787]	[512,821,886,589]	-3	hSpCas9	negative selection	9248264
2988744	2988767	4	+	27260156	TC71	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.002913317879345345	[920]	[901,1078,967,994]	0	hSpCas9	negative selection	9305254
2992220	2992243	4	+	27260156	TC71	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.7421526660127267	[55]	[33,12,47,48]	-9	hSpCas9	negative selection	9305255
2988793	2988816	4	+	27260156	TC71	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	0.26537804582836233	[182]	[220,238,217,267]	6	hSpCas9	negative selection	9305256
3004258	3004281	4	-	27260156	TC71	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.14996544403200696	[679]	[727,801,864,841]	4	hSpCas9	negative selection	9369513
3004316	3004339	4	-	27260156	TC71	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.2139883345866067	[970]	[1352,1243,1003,1232]	5	hSpCas9	negative selection	9369514
2992244	2992267	4	-	27260156	TC71	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.053100761681603714	[787]	[726,842,924,1020]	1	hSpCas9	negative selection	9369515
2988744	2988767	4	+	27260156	TC32	viability	CTTTGTGACAAGCAACCGATAGG	GRK4	ENSG00000125388	-0.035204375274165756	[920]	[758,727,1018,908]	0	hSpCas9	negative selection	9426505
2992220	2992243	4	+	27260156	TC32	viability	ATATGAAGTTGCCGATGATGAGG	GRK4	ENSG00000125388	-0.7426692093733642	[55]	[14,16,54,49]	-9	hSpCas9	negative selection	9426506
2988793	2988816	4	+	27260156	TC32	viability	ATACCAAACCCACTCTAAAGAGG	GRK4	ENSG00000125388	-0.035186813328171196	[182]	[108,200,219,131]	0	hSpCas9	negative selection	9426507
3004258	3004281	4	-	27260156	TC32	viability	CTACATTCTGTCACAACATCTGG	GRK4	ENSG00000125388	0.23279509220109917	[679]	[602,647,1011,800]	4	hSpCas9	negative selection	9490764
3004316	3004339	4	-	27260156	TC32	viability	TTACCTAGTACATTCCTCAAAGG	GRK4	ENSG00000125388	0.27300203373755183	[970]	[1023,786,1532,1211]	5	hSpCas9	negative selection	9490765
2992244	2992267	4	-	27260156	TC32	viability	TTGACAGTCCACAATCACTTCGG	GRK4	ENSG00000125388	0.1253662425208354	[787]	[689,518,1215,964]	2	hSpCas9	negative selection	9490766
2963970	2963993	4	+	27869803	HPAFII	viability after 27 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.25105071407147117	[118]	[56,88,NaN]	2	hSpCas9	negative selection	9588006
2965306	2965329	4	-	27869803	HPAFII	viability after 27 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.7018651653876649	[842]	[1117,389,NaN]	6	hSpCas9	negative selection	9588007
2984580	2984603	4	-	27869803	HPAFII	viability after 27 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.06940072250796789	[216]	[105,110,NaN]	0	hSpCas9	negative selection	9588008
3013694	3013717	4	+	27869803	HPAFII	viability after 27 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.14585415590665274	[122]	[76,66,NaN]	1	hSpCas9	negative selection	9588009
3019688	3019711	4	+	27869803	HPAFII	viability after 27 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	-0.24919171246288402	[215]	[88,100,NaN]	-2	hSpCas9	negative selection	9588010
3035454	3035477	4	-	27869803	HPAFII	viability after 27 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.7282437288760946	[173]	[84,206,NaN]	6	hSpCas9	negative selection	9588011
2963970	2963993	4	+	27869803	HPAFII	viability after 15 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.3006263439556307	[118]	[48,224,NaN]	3	hSpCas9	negative selection	9670455
2965306	2965329	4	-	27869803	HPAFII	viability after 15 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.6244448145937065	[842]	[2632,627,NaN]	7	hSpCas9	negative selection	9670456
2984580	2984603	4	-	27869803	HPAFII	viability after 15 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.2886305945179696	[216]	[148,216,NaN]	-3	hSpCas9	negative selection	9670457
3013694	3013717	4	+	27869803	HPAFII	viability after 15 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.297158260791446	[122]	[122,97,NaN]	-3	hSpCas9	negative selection	9670458
3019688	3019711	4	+	27869803	HPAFII	viability after 15 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.3646027225256712	[215]	[354,263,NaN]	4	hSpCas9	negative selection	9670459
3035454	3035477	4	-	27869803	HPAFII	viability after 15 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.2743209683748511	[173]	[219,229,NaN]	3	hSpCas9	negative selection	9670460
2963970	2963993	4	+	27869803	ASPC1	viability after 36 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	1.1069242033385867	[278]	[638,38,41]	9	hSpCas9	negative selection	9752904
2965306	2965329	4	-	27869803	ASPC1	viability after 36 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.9869184401512756	[2056]	[1816,1073,1408]	8	hSpCas9	negative selection	9752905
2984580	2984603	4	-	27869803	ASPC1	viability after 36 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.6418033303701549	[427]	[373,247,119]	6	hSpCas9	negative selection	9752906
3013694	3013717	4	+	27869803	ASPC1	viability after 36 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.8944030634670267	[383]	[55,145,23]	-7	hSpCas9	negative selection	9752907
3019688	3019711	4	+	27869803	ASPC1	viability after 36 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.4134136208791018	[536]	[300,357,124]	4	hSpCas9	negative selection	9752908
3035454	3035477	4	-	27869803	ASPC1	viability after 36 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.0234526738688976	[542]	[384,190,56]	0	hSpCas9	negative selection	9752909
2963970	2963993	4	+	27869803	PATU8988S	viability after 35 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.6732487224668009	[266]	[162,179,NaN]	7	hSpCas9	negative selection	9835353
2965306	2965329	4	-	27869803	PATU8988S	viability after 35 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.05450722894790805	[1948]	[895,733,NaN]	0	hSpCas9	negative selection	9835354
2984580	2984603	4	-	27869803	PATU8988S	viability after 35 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.2775491963381884	[309]	[103,101,NaN]	-3	hSpCas9	negative selection	9835355
3013694	3013717	4	+	27869803	PATU8988S	viability after 35 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.6950871162978349	[241]	[67,247,NaN]	7	hSpCas9	negative selection	9835356
3019688	3019711	4	+	27869803	PATU8988S	viability after 35 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.5775659110596648	[481]	[376,201,NaN]	6	hSpCas9	negative selection	9835357
3035454	3035477	4	-	27869803	PATU8988S	viability after 35 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.2927976004937527	[393]	[145,242,NaN]	3	hSpCas9	negative selection	9835358
2963970	2963993	4	+	27869803	PATU8988S	viability after 31 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	0.5547759244881593	[266]	[107,217,NaN]	6	hSpCas9	negative selection	9917802
2965306	2965329	4	-	27869803	PATU8988S	viability after 31 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	-0.12632234753606064	[1948]	[700,725,NaN]	-1	hSpCas9	negative selection	9917803
2984580	2984603	4	-	27869803	PATU8988S	viability after 31 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.08526047827508854	[309]	[101,134,NaN]	-1	hSpCas9	negative selection	9917804
3013694	3013717	4	+	27869803	PATU8988S	viability after 31 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.5580650796219064	[241]	[94,201,NaN]	6	hSpCas9	negative selection	9917805
3019688	3019711	4	+	27869803	PATU8988S	viability after 31 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.2616116783384663	[481]	[258,193,NaN]	3	hSpCas9	negative selection	9917806
3035454	3035477	4	-	27869803	PATU8988S	viability after 31 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.3958463519101676	[393]	[134,297,NaN]	5	hSpCas9	negative selection	9917807
2963970	2963993	4	+	27869803	HPAFII	viability after 35 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	-0.13199170569830443	[118]	[6,108,NaN]	-1	hSpCas9	negative selection	10000251
2965306	2965329	4	-	27869803	HPAFII	viability after 35 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	1.03426096850165	[842]	[1199,506,NaN]	7	hSpCas9	negative selection	10000252
2984580	2984603	4	-	27869803	HPAFII	viability after 35 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	-0.2841290143831675	[216]	[53,130,NaN]	-2	hSpCas9	negative selection	10000253
3013694	3013717	4	+	27869803	HPAFII	viability after 35 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	0.17227442516013647	[122]	[48,93,NaN]	1	hSpCas9	negative selection	10000254
3019688	3019711	4	+	27869803	HPAFII	viability after 35 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.42733881870478396	[215]	[123,172,NaN]	2	hSpCas9	negative selection	10000255
3035454	3035477	4	-	27869803	HPAFII	viability after 35 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.6232916943622387	[173]	[98,176,NaN]	4	hSpCas9	negative selection	10000256
2963970	2963993	4	+	27869803	HPAFII	viability after 31 days	TGCCCGGCGAGCTATGCACGGGG	GRK4	ENSG00000125388	-0.172007788607474	[118]	[31,88,NaN]	-1	hSpCas9	negative selection	10082700
2965306	2965329	4	-	27869803	HPAFII	viability after 31 days	CGAGACAGAGGATTGCACAGAGG	GRK4	ENSG00000125388	0.7979043618146171	[842]	[1146,468,NaN]	6	hSpCas9	negative selection	10082701
2984580	2984603	4	-	27869803	HPAFII	viability after 31 days	AATGTCTAAGCTCACTGCACTGG	GRK4	ENSG00000125388	0.09426704703988484	[216]	[118,141,NaN]	0	hSpCas9	negative selection	10082702
3013694	3013717	4	+	27869803	HPAFII	viability after 31 days	GCCTGTCAAGTGCGAGCCACAGG	GRK4	ENSG00000125388	-0.6607614708441027	[122]	[24,63,NaN]	-4	hSpCas9	negative selection	10082703
3019688	3019711	4	+	27869803	HPAFII	viability after 31 days	GCTCACCATTATGAATGGAGGGG	GRK4	ENSG00000125388	0.36678952094940254	[215]	[140,172,NaN]	2	hSpCas9	negative selection	10082704
3035454	3035477	4	-	27869803	HPAFII	viability after 31 days	AGTTGATGTCCTTGAACACGGGG	GRK4	ENSG00000125388	0.9702284994319065	[173]	[108,280,NaN]	7	hSpCas9	negative selection	10082705
3013759	3013782	4	+	28162770	P31FUJ	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.19069687361266108	[84]	[113]	2	hSpCas9	negative selection	10165866
2964070	2964093	4	+	28162770	P31FUJ	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-0.05480390243638422	[98]	[111]	0	hSpCas9	negative selection	10165867
3019792	3019815	4	+	28162770	P31FUJ	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.17174292104682282	[206]	[273]	1	hSpCas9	negative selection	10165868
3029310	3029333	4	+	28162770	P31FUJ	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	1.1645332931310064	[40]	[107]	9	hSpCas9	negative selection	10165869
3037496	3037519	4	-	28162770	P31FUJ	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	-0.3497583507602279	[243]	[224]	-3	hSpCas9	negative selection	10165870
3004255	3004278	4	-	28162770	P31FUJ	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.24274907958619563	[355]	[494]	2	hSpCas9	negative selection	10165871
3019686	3019709	4	+	28162770	P31FUJ	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.31509820208523265	[367]	[537]	3	hSpCas9	negative selection	10165872
3027931	3027954	4	-	28162770	P31FUJ	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.06700307957484353	[367]	[452]	0	hSpCas9	negative selection	10165873
3027945	3027968	4	+	28162770	P31FUJ	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.4250918187606288	[134]	[212]	5	hSpCas9	negative selection	10165874
3037403	3037426	4	+	28162770	P31FUJ	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.5428586797952727	[308]	[528]	6	hSpCas9	negative selection	10165875
3013759	3013782	4	+	28162770	TF1	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10335232
2964070	2964093	4	+	28162770	TF1	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10335233
3019792	3019815	4	+	28162770	TF1	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	NaN	[NaN]	[252]	1	hSpCas9	negative selection	10335234
3029310	3029333	4	+	28162770	TF1	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10335235
3037496	3037519	4	-	28162770	TF1	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10335236
3004255	3004278	4	-	28162770	TF1	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10335237
3019686	3019709	4	+	28162770	TF1	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	NaN	[NaN]	[351]	1	hSpCas9	negative selection	10335238
3027931	3027954	4	-	28162770	TF1	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	NaN	[NaN]	[300]	1	hSpCas9	negative selection	10335239
3027945	3027968	4	+	28162770	TF1	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10335240
3037403	3037426	4	+	28162770	TF1	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	NaN	[NaN]	[475]	1	hSpCas9	negative selection	10335241
3013759	3013782	4	+	28162770	SKM1	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.4555322775069034	[32]	[79]	4	hSpCas9	negative selection	10504598
2964070	2964093	4	+	28162770	SKM1	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.48833842259014504	[24]	[61]	5	hSpCas9	negative selection	10504599
3019792	3019815	4	+	28162770	SKM1	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	1.569109962011358	[56]	[298]	9	hSpCas9	negative selection	10504600
3029310	3029333	4	+	28162770	SKM1	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	-1.7065244806020692	[23]	[12]	-8	hSpCas9	negative selection	10504601
3037496	3037519	4	-	28162770	SKM1	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.6068416007818688	[77]	[209]	6	hSpCas9	negative selection	10504602
3004255	3004278	4	-	28162770	SKM1	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.2859487977817957	[99]	[144]	-2	hSpCas9	negative selection	10504603
3019686	3019709	4	+	28162770	SKM1	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.23313985617045546	[76]	[159]	2	hSpCas9	negative selection	10504604
3027931	3027954	4	-	28162770	SKM1	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.5389959615439492	[101]	[261]	5	hSpCas9	negative selection	10504605
3027945	3027968	4	+	28162770	SKM1	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.9652689779922663	[30]	[106]	8	hSpCas9	negative selection	10504606
3037403	3037426	4	+	28162770	SKM1	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.8525980151838269	[51]	[165]	7	hSpCas9	negative selection	10504607
3013759	3013782	4	+	28162770	SKM1	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.4555322775069034	[32]	[79]	4	hSpCas9	negative selection	10673964
2964070	2964093	4	+	28162770	SKM1	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.48833842259014504	[24]	[61]	5	hSpCas9	negative selection	10673965
3019792	3019815	4	+	28162770	SKM1	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	1.569109962011358	[56]	[298]	9	hSpCas9	negative selection	10673966
3029310	3029333	4	+	28162770	SKM1	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	-1.7065244806020692	[23]	[12]	-8	hSpCas9	negative selection	10673967
3037496	3037519	4	-	28162770	SKM1	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.6068416007818688	[77]	[209]	6	hSpCas9	negative selection	10673968
3004255	3004278	4	-	28162770	SKM1	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.2859487977817957	[99]	[144]	-2	hSpCas9	negative selection	10673969
3019686	3019709	4	+	28162770	SKM1	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.23313985617045546	[76]	[159]	2	hSpCas9	negative selection	10673970
3027931	3027954	4	-	28162770	SKM1	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.5389959615439492	[101]	[261]	5	hSpCas9	negative selection	10673971
3027945	3027968	4	+	28162770	SKM1	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.9652689779922663	[30]	[106]	8	hSpCas9	negative selection	10673972
3037403	3037426	4	+	28162770	SKM1	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.8525980151838269	[51]	[165]	7	hSpCas9	negative selection	10673973
3013759	3013782	4	+	28162770	PL21	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	1.0575352190465197	[84]	[76]	8	hSpCas9	negative selection	10843330
2964070	2964093	4	+	28162770	PL21	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.003742401685816521	[54]	[23]	0	hSpCas9	negative selection	10843331
3019792	3019815	4	+	28162770	PL21	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.10136146001114665	[271]	[126]	0	hSpCas9	negative selection	10843332
3029310	3029333	4	+	28162770	PL21	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	-1.7432768571443122	[99]	[12]	-8	hSpCas9	negative selection	10843333
3037496	3037519	4	-	28162770	PL21	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.21040794994314727	[279]	[140]	1	hSpCas9	negative selection	10843334
3004255	3004278	4	-	28162770	PL21	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.5432135182482313	[297]	[188]	5	hSpCas9	negative selection	10843335
3019686	3019709	4	+	28162770	PL21	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	1.1947863799951133	[269]	[268]	8	hSpCas9	negative selection	10843336
3027931	3027954	4	-	28162770	PL21	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	-0.3289141450811797	[328]	[113]	-2	hSpCas9	negative selection	10843337
3027945	3027968	4	+	28162770	PL21	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	-0.016178292437443398	[157]	[67]	0	hSpCas9	negative selection	10843338
3037403	3037426	4	+	28162770	PL21	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.4920956296256236	[213]	[130]	4	hSpCas9	negative selection	10843339
3013759	3013782	4	+	28162770	P31FUJ	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.19069687361266108	[84]	[113]	2	hSpCas9	negative selection	11012696
2964070	2964093	4	+	28162770	P31FUJ	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-0.05480390243638422	[98]	[111]	0	hSpCas9	negative selection	11012697
3019792	3019815	4	+	28162770	P31FUJ	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.17174292104682282	[206]	[273]	1	hSpCas9	negative selection	11012698
3029310	3029333	4	+	28162770	P31FUJ	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	1.1645332931310064	[40]	[107]	9	hSpCas9	negative selection	11012699
3037496	3037519	4	-	28162770	P31FUJ	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	-0.3497583507602279	[243]	[224]	-3	hSpCas9	negative selection	11012700
3004255	3004278	4	-	28162770	P31FUJ	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.24274907958619563	[355]	[494]	2	hSpCas9	negative selection	11012701
3019686	3019709	4	+	28162770	P31FUJ	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.31509820208523265	[367]	[537]	3	hSpCas9	negative selection	11012702
3027931	3027954	4	-	28162770	P31FUJ	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.06700307957484353	[367]	[452]	0	hSpCas9	negative selection	11012703
3027945	3027968	4	+	28162770	P31FUJ	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.4250918187606288	[134]	[212]	5	hSpCas9	negative selection	11012704
3037403	3037426	4	+	28162770	P31FUJ	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.5428586797952727	[308]	[528]	6	hSpCas9	negative selection	11012705
3013759	3013782	4	+	28162770	OCIAML5	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	-0.9329865662475644	[109]	[103]	-5	hSpCas9	negative selection	11182062
2964070	2964093	4	+	28162770	OCIAML5	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.23539627038634237	[47]	[101]	2	hSpCas9	negative selection	11182063
3019792	3019815	4	+	28162770	OCIAML5	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.2652903797741618	[176]	[383]	2	hSpCas9	negative selection	11182064
3029310	3029333	4	+	28162770	OCIAML5	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.16783298657370782	[35]	[72]	1	hSpCas9	negative selection	11182065
3037496	3037519	4	-	28162770	OCIAML5	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.334554719450629	[104]	[238]	3	hSpCas9	negative selection	11182066
3004255	3004278	4	-	28162770	OCIAML5	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.46873793131249136	[183]	[239]	-3	hSpCas9	negative selection	11182067
3019686	3019709	4	+	28162770	OCIAML5	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.3798801571856997	[214]	[504]	3	hSpCas9	negative selection	11182068
3027931	3027954	4	-	28162770	OCIAML5	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.3426618215788879	[172]	[395]	3	hSpCas9	negative selection	11182069
3027945	3027968	4	+	28162770	OCIAML5	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	1.222820640766995	[60]	[256]	9	hSpCas9	negative selection	11182070
3037403	3037426	4	+	28162770	OCIAML5	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	-0.0397894501016669	[208]	[366]	0	hSpCas9	negative selection	11182071
3013759	3013782	4	+	28162770	EOL1	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	-1.5382428591566775	[214]	[38]	-7	hSpCas9	negative selection	11351428
2964070	2964093	4	+	28162770	EOL1	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.2173295207983803	[79]	[48]	2	hSpCas9	negative selection	11351429
3019792	3019815	4	+	28162770	EOL1	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	-0.4135657510577664	[492]	[194]	-3	hSpCas9	negative selection	11351430
3029310	3029333	4	+	28162770	EOL1	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	2.0284987356094426	[86]	[186]	9	hSpCas9	negative selection	11351431
3037496	3037519	4	-	28162770	EOL1	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	-1.2560244740712863	[543]	[119]	-7	hSpCas9	negative selection	11351432
3004255	3004278	4	-	28162770	EOL1	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.6958138233602599	[531]	[453]	6	hSpCas9	negative selection	11351433
3019686	3019709	4	+	28162770	EOL1	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.4244161111292622	[354]	[250]	4	hSpCas9	negative selection	11351434
3027931	3027954	4	-	28162770	EOL1	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	-0.12864516759505884	[441]	[212]	-1	hSpCas9	negative selection	11351435
3027945	3027968	4	+	28162770	EOL1	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.1984092078886841	[176]	[106]	1	hSpCas9	negative selection	11351436
3037403	3037426	4	+	28162770	EOL1	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	1.0541074053394506	[297]	[325]	8	hSpCas9	negative selection	11351437
3013759	3013782	4	+	28162770	MOLM13	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	1.4151019671851435	[166]	[321]	9	hSpCas9	negative selection	11520794
2964070	2964093	4	+	28162770	MOLM13	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-4.426928381763365	[118]	[3]	-9	hSpCas9	negative selection	11520795
3019792	3019815	4	+	28162770	MOLM13	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	-0.6885121757979878	[291]	[130]	-4	hSpCas9	negative selection	11520796
3029310	3029333	4	+	28162770	MOLM13	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.4081831354203109	[73]	[70]	3	hSpCas9	negative selection	11520797
3037496	3037519	4	-	28162770	MOLM13	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.45922452041745127	[333]	[331]	3	hSpCas9	negative selection	11520798
3004255	3004278	4	-	28162770	MOLM13	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-0.4635068044563977	[615]	[322]	-3	hSpCas9	negative selection	11520799
3019686	3019709	4	+	28162770	MOLM13	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	-0.0898365349027751	[445]	[302]	0	hSpCas9	negative selection	11520800
3027931	3027954	4	-	28162770	MOLM13	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	1.1785953474253323	[376]	[616]	8	hSpCas9	negative selection	11520801
3027945	3027968	4	+	28162770	MOLM13	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.6251291233557761	[164]	[183]	5	hSpCas9	negative selection	11520802
3037403	3037426	4	+	28162770	MOLM13	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.7917969348365369	[436]	[546]	6	hSpCas9	negative selection	11520803
3013759	3013782	4	+	28162770	HEL	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.23486112429437922	[133]	[100]	2	hSpCas9	negative selection	11690160
2964070	2964093	4	+	28162770	HEL	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-1.630279662406059	[86]	[17]	-7	hSpCas9	negative selection	11690161
3019792	3019815	4	+	28162770	HEL	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.49894904540299095	[252]	[228]	4	hSpCas9	negative selection	11690162
3029310	3029333	4	+	28162770	HEL	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.36811645189135134	[74]	[61]	3	hSpCas9	negative selection	11690163
3037496	3037519	4	-	28162770	HEL	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.11857961034140052	[301]	[209]	1	hSpCas9	negative selection	11690164
3004255	3004278	4	-	28162770	HEL	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.629503004843663	[437]	[433]	5	hSpCas9	negative selection	11690165
3019686	3019709	4	+	28162770	HEL	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	-0.5499062459420387	[399]	[174]	-4	hSpCas9	negative selection	11690166
3027931	3027954	4	-	28162770	HEL	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.738316491982588	[291]	[311]	6	hSpCas9	negative selection	11690167
3027945	3027968	4	+	28162770	HEL	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.15952983007993382	[129]	[92]	1	hSpCas9	negative selection	11690168
3037403	3037426	4	+	28162770	HEL	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	-0.4071863933313253	[293]	[141]	-3	hSpCas9	negative selection	11690169
3013759	3013782	4	+	28162770	MV411	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.28277062389505603	[120]	[123]	2	hSpCas9	negative selection	11859526
2964070	2964093	4	+	28162770	MV411	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-0.5599173712748289	[55]	[31]	-4	hSpCas9	negative selection	11859527
3019792	3019815	4	+	28162770	MV411	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.03872006634340386	[244]	[211]	0	hSpCas9	negative selection	11859528
3029310	3029333	4	+	28162770	MV411	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.6701286226050542	[46]	[62]	6	hSpCas9	negative selection	11859529
3037496	3037519	4	-	28162770	MV411	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	-0.027422290447808195	[293]	[242]	0	hSpCas9	negative selection	11859530
3004255	3004278	4	-	28162770	MV411	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	1.3254400627840481	[305]	[645]	9	hSpCas9	negative selection	11859531
3019686	3019709	4	+	28162770	MV411	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.3643936971286245	[224]	[243]	3	hSpCas9	negative selection	11859532
3027931	3027954	4	-	28162770	MV411	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	-0.1124583943036076	[307]	[239]	-1	hSpCas9	negative selection	11859533
3027945	3027968	4	+	28162770	MV411	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	1.2817890555735523	[82]	[169]	9	hSpCas9	negative selection	11859534
3037403	3037426	4	+	28162770	MV411	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	1.1212790006268498	[208]	[382]	8	hSpCas9	negative selection	11859535
3013759	3013782	4	+	28162770	MONOMAC1	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.324500273519969	[61]	[88]	3	hSpCas9	negative selection	12028892
2964070	2964093	4	+	28162770	MONOMAC1	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-1.499599617079985	[36]	[14]	-8	hSpCas9	negative selection	12028893
3019792	3019815	4	+	28162770	MONOMAC1	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.8300992828779601	[157]	[321]	7	hSpCas9	negative selection	12028894
3029310	3029333	4	+	28162770	MONOMAC1	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	-0.4431974343289513	[50]	[42]	-4	hSpCas9	negative selection	12028895
3037496	3037519	4	-	28162770	MONOMAC1	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	-0.46131014952670624	[232]	[193]	-4	hSpCas9	negative selection	12028896
3004255	3004278	4	-	28162770	MONOMAC1	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.022054211186642858	[249]	[290]	0	hSpCas9	negative selection	12028897
3019686	3019709	4	+	28162770	MONOMAC1	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.3621164673119972	[187]	[276]	3	hSpCas9	negative selection	12028898
3027931	3027954	4	-	28162770	MONOMAC1	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.03916137380192464	[207]	[244]	0	hSpCas9	negative selection	12028899
3027945	3027968	4	+	28162770	MONOMAC1	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.7358489570819096	[76]	[146]	7	hSpCas9	negative selection	12028900
3037403	3037426	4	+	28162770	MONOMAC1	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.18808507431500265	[133]	[174]	2	hSpCas9	negative selection	12028901
3013759	3013782	4	+	28162770	OCIAML2	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.35453637293190354	[22]	[162]	3	hSpCas9	negative selection	12198258
2964070	2964093	4	+	28162770	OCIAML2	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	0.6992951762001511	[5]	[53]	6	hSpCas9	negative selection	12198259
3019792	3019815	4	+	28162770	OCIAML2	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	0.292929978935758	[42]	[291]	3	hSpCas9	negative selection	12198260
3029310	3029333	4	+	28162770	OCIAML2	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	-0.6980403213452337	[11]	[40]	-5	hSpCas9	negative selection	12198261
3037496	3037519	4	-	28162770	OCIAML2	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	-0.2420982668083067	[66]	[313]	-2	hSpCas9	negative selection	12198262
3004255	3004278	4	-	28162770	OCIAML2	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	0.6843757563644121	[53]	[480]	6	hSpCas9	negative selection	12198263
3019686	3019709	4	+	28162770	OCIAML2	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.21119421473158384	[47]	[307]	2	hSpCas9	negative selection	12198264
3027931	3027954	4	-	28162770	OCIAML2	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	0.09673861546425677	[54]	[325]	0	hSpCas9	negative selection	12198265
3027945	3027968	4	+	28162770	OCIAML2	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	-0.1384333949009719	[27]	[140]	-1	hSpCas9	negative selection	12198266
3037403	3037426	4	+	28162770	OCIAML2	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	0.6780474424961118	[37]	[336]	6	hSpCas9	negative selection	12198267
3013759	3013782	4	+	28162770	OCIAML3	viability	GAAGAGGAAAGGTGAAGCTATGG	GRK4	ENSG00000125388	0.9748351950337162	[29]	[177]	8	hSpCas9	negative selection	12367624
2964070	2964093	4	+	28162770	OCIAML3	viability	CATGGAGCTCGAGAACATCGTGG	GRK4	ENSG00000125388	-0.8935679221830708	[15]	[25]	-6	hSpCas9	negative selection	12367625
3019792	3019815	4	+	28162770	OCIAML3	viability	GCGGCTTGGAAGATTTACAGAGG	GRK4	ENSG00000125388	1.33132556023782	[56]	[432]	9	hSpCas9	negative selection	12367626
3029310	3029333	4	+	28162770	OCIAML3	viability	AGAGAAAGTCAAATGGGAGGAGG	GRK4	ENSG00000125388	0.05806905625553016	[13]	[43]	0	hSpCas9	negative selection	12367627
3037496	3037519	4	-	28162770	OCIAML3	viability	GCAGTACCTCATTCTGCCAGGGG	GRK4	ENSG00000125388	0.2770059189557589	[75]	[277]	2	hSpCas9	negative selection	12367628
3004255	3004278	4	-	28162770	OCIAML3	viability	CATTCTGTCACAACATCTGGAGG	GRK4	ENSG00000125388	-1.1599118052296347	[93]	[126]	-7	hSpCas9	negative selection	12367629
3019686	3019709	4	+	28162770	OCIAML3	viability	GTGCTCACCATTATGAATGGAGG	GRK4	ENSG00000125388	0.5173534686235407	[80]	[349]	5	hSpCas9	negative selection	12367630
3027931	3027954	4	-	28162770	OCIAML3	viability	GGATCTCTGTGGCCAAACCGAGG	GRK4	ENSG00000125388	-0.2891530587957423	[84]	[209]	-2	hSpCas9	negative selection	12367631
3027945	3027968	4	+	28162770	OCIAML3	viability	CAGAGATCCCAGAAGGACAGAGG	GRK4	ENSG00000125388	0.6244158788093391	[25]	[120]	6	hSpCas9	negative selection	12367632
3037403	3037426	4	+	28162770	OCIAML3	viability	GGATATCGAGCAGTTCTCGGTGG	GRK4	ENSG00000125388	-0.05018383439649354	[82]	[241]	0	hSpCas9	negative selection	12367633