Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:57531
• Symbol:HACE1
• Description:HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/HACE1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
104859627	104859650	6	-	26472758	Jiyoye	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-3.7760464425498967	[108]	[5]	-9	hSpCas9	negative selection	69059
104785156	104785179	6	+	26472758	Jiyoye	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	1.4148289540493089	[93]	[188]	8	hSpCas9	negative selection	69060
104859567	104859590	6	-	26472758	Jiyoye	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.8222128807847171	[113]	[151]	6	hSpCas9	negative selection	69061
104811368	104811391	6	-	26472758	Jiyoye	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.30674529066599576	[460]	[429]	2	hSpCas9	negative selection	69062
104785297	104785320	6	+	26472758	Jiyoye	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	-0.1327533656007791	[204]	[140]	-1	hSpCas9	negative selection	69063
104777205	104777228	6	-	26472758	Jiyoye	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.38058117149416026	[218]	[214]	3	hSpCas9	negative selection	69064
104730375	104730398	6	-	26472758	Jiyoye	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.932266426249631	[81]	[117]	6	hSpCas9	negative selection	69065
104796648	104796671	6	+	26472758	Jiyoye	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.8728389538546852	[125]	[173]	6	hSpCas9	negative selection	69066
104859627	104859650	6	-	26472758	KBM7	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-2.7777132223100525	[170,208]	[8,16]	-9	hSpCas9	negative selection	260177
104785156	104785179	6	+	26472758	KBM7	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.07980450703319987	[496,358]	[158,255]	0	hSpCas9	negative selection	260178
104859567	104859590	6	-	26472758	KBM7	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.9179266565134154	[517,305]	[307,402]	8	hSpCas9	negative selection	260179
104811368	104811391	6	-	26472758	KBM7	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.4596439318167018	[2141,1693]	[1440,1043]	5	hSpCas9	negative selection	260180
104785297	104785320	6	+	26472758	KBM7	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.4289577605615037	[791,578]	[369,481]	4	hSpCas9	negative selection	260181
104777205	104777228	6	-	26472758	KBM7	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	-0.09375765613612186	[872,772]	[321,397]	-1	hSpCas9	negative selection	260182
104730375	104730398	6	-	26472758	KBM7	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	-0.13711053550083785	[424,258]	[61,215]	-1	hSpCas9	negative selection	260183
104796648	104796671	6	+	26472758	KBM7	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.4907588118241849	[564,568]	[327,419]	5	hSpCas9	negative selection	260184
104859627	104859650	6	-	26472758	Raji	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-1.1214351551222814	[74]	[7]	-7	hSpCas9	negative selection	451295
104785156	104785179	6	+	26472758	Raji	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	-0.018880237272573153	[178]	[40]	0	hSpCas9	negative selection	451296
104859567	104859590	6	-	26472758	Raji	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.9887390388749804	[151]	[69]	8	hSpCas9	negative selection	451297
104811368	104811391	6	-	26472758	Raji	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.7246637563674838	[823]	[315]	6	hSpCas9	negative selection	451298
104785297	104785320	6	+	26472758	Raji	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	-0.6496397111338601	[506]	[74]	-5	hSpCas9	negative selection	451299
104777205	104777228	6	-	26472758	Raji	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	-0.29979184613227383	[365]	[68]	-3	hSpCas9	negative selection	451300
104730375	104730398	6	-	26472758	Raji	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.5548425123448206	[175]	[59]	5	hSpCas9	negative selection	451301
104796648	104796671	6	+	26472758	Raji	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.6303363738193307	[308]	[110]	6	hSpCas9	negative selection	451302
104859627	104859650	6	-	26472758	K562	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-3.393011192948845	[111]	[8]	-8	hSpCas9	negative selection	642413
104785156	104785179	6	+	26472758	K562	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.1912480686451091	[303]	[292]	1	hSpCas9	negative selection	642414
104859567	104859590	6	-	26472758	K562	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.6567721423740792	[268]	[357]	5	hSpCas9	negative selection	642415
104811368	104811391	6	-	26472758	K562	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.6151148807922155	[1494]	[1932]	5	hSpCas9	negative selection	642416
104785297	104785320	6	+	26472758	K562	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	-0.7529071380352275	[538]	[269]	-4	hSpCas9	negative selection	642417
104777205	104777228	6	-	26472758	K562	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.5341382416434736	[615]	[752]	4	hSpCas9	negative selection	642418
104730375	104730398	6	-	26472758	K562	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	-0.5058029632020261	[327]	[194]	-3	hSpCas9	negative selection	642419
104796648	104796671	6	+	26472758	K562	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	-0.27933387193770687	[472]	[328]	-2	hSpCas9	negative selection	642420
104771974	104771997	6	-	26627737	DLD1	viability	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.6324787473603836	[285]	[44,49,74]	-6	hSpCas9	negative selection	829900
104777200	104777223	6	+	26627737	DLD1	viability	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	-0.6921907284241045	[458]	[129,7,119]	-6	hSpCas9	negative selection	829901
104785161	104785184	6	+	26627737	DLD1	viability	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	-0.23996251033466834	[588]	[198,129,139]	-3	hSpCas9	negative selection	829902
104852316	104852339	6	-	26627737	DLD1	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.10405976436641706	[671]	[316,139,135]	-1	hSpCas9	negative selection	829905
104859566	104859589	6	-	26627737	DLD1	viability	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.6320548895863798	[1392]	[52,591,220]	-6	hSpCas9	negative selection	829906
104771974	104771997	6	-	26627737	GBM cells	viability after 5 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.26402469624051994	[102]	[40,50]	-4	hSpCas9	negative selection	912215
104777200	104777223	6	+	26627737	GBM cells	viability after 5 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.30281081655932907	[129]	[85,85]	5	hSpCas9	negative selection	912216
104785161	104785184	6	+	26627737	GBM cells	viability after 5 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	-0.07683857886763701	[353]	[184,174]	-1	hSpCas9	negative selection	912217
104852316	104852339	6	-	26627737	GBM cells	viability after 5 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.4476561876940885	[241]	[183,169]	6	hSpCas9	negative selection	912220
104859566	104859589	6	-	26627737	GBM cells	viability after 5 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.17034878755142827	[319]	[147,156]	-3	hSpCas9	negative selection	912221
104771974	104771997	6	-	26627737	GBM cells	viability after 13 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.5459006484509981	[102]	[45,31]	-6	hSpCas9	negative selection	994530
104777200	104777223	6	+	26627737	GBM cells	viability after 13 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.5735766553486764	[129]	[115,95]	7	hSpCas9	negative selection	994531
104785161	104785184	6	+	26627737	GBM cells	viability after 13 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.052720512132583996	[353]	[228,174]	0	hSpCas9	negative selection	994532
104852316	104852339	6	-	26627737	GBM cells	viability after 13 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.4603872823030409	[241]	[194,168]	6	hSpCas9	negative selection	994535
104859566	104859589	6	-	26627737	GBM cells	viability after 13 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.31380382639303284	[319]	[126,149]	-4	hSpCas9	negative selection	994536
104771974	104771997	6	-	26627737	GBM cells	viability after 21 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-1.80626722756756	[102]	[15,15]	-8	hSpCas9	negative selection	1076845
104777200	104777223	6	+	26627737	GBM cells	viability after 21 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	2.0508157899794064	[129]	[312,273]	9	hSpCas9	negative selection	1076846
104785161	104785184	6	+	26627737	GBM cells	viability after 21 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.004420180067399082	[353]	[194,190]	0	hSpCas9	negative selection	1076847
104852316	104852339	6	-	26627737	GBM cells	viability after 21 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.6287576164230617	[241]	[219,187]	6	hSpCas9	negative selection	1076850
104859566	104859589	6	-	26627737	GBM cells	viability after 21 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.08453381790655995	[319]	[164,162]	0	hSpCas9	negative selection	1076851
104771974	104771997	6	-	26627737	RPE1	viability after 9 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.28176178293120024	[590]	[189,269]	2	hSpCas9	negative selection	1159160
104777200	104777223	6	+	26627737	RPE1	viability after 9 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.7511300266042137	[647]	[254,452]	5	hSpCas9	negative selection	1159161
104785161	104785184	6	+	26627737	RPE1	viability after 9 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.279421814271154	[1146]	[351,543]	2	hSpCas9	negative selection	1159162
104852316	104852339	6	-	26627737	RPE1	viability after 9 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	1.1265503167130673	[633]	[304,598]	7	hSpCas9	negative selection	1159165
104859566	104859589	6	-	26627737	RPE1	viability after 9 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.007505949852294913	[1296]	[189,679]	0	hSpCas9	negative selection	1159166
104771974	104771997	6	-	26627737	RPE1	viability after 12 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.2993837485766282	[590]	[140,252]	2	hSpCas9	negative selection	1241475
104777200	104777223	6	+	26627737	RPE1	viability after 12 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.3824466798033684	[647]	[275,174]	2	hSpCas9	negative selection	1241476
104785161	104785184	6	+	26627737	RPE1	viability after 12 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.5907980306366718	[1146]	[433,495]	4	hSpCas9	negative selection	1241477
104852316	104852339	6	-	26627737	RPE1	viability after 12 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	1.5043343294476514	[633]	[354,618]	8	hSpCas9	negative selection	1241480
104859566	104859589	6	-	26627737	RPE1	viability after 12 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.23472927966382517	[1296]	[189,642]	1	hSpCas9	negative selection	1241481
104771974	104771997	6	-	26627737	RPE1	viability after 15 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.8256868233967292	[590]	[278,312]	5	hSpCas9	negative selection	1323790
104777200	104777223	6	+	26627737	RPE1	viability after 15 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.2840789265145058	[647]	[395,494]	7	hSpCas9	negative selection	1323791
104785161	104785184	6	+	26627737	RPE1	viability after 15 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.4198985944984628	[1146]	[457,410]	2	hSpCas9	negative selection	1323792
104852316	104852339	6	-	26627737	RPE1	viability after 15 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	1.4503608278483076	[633]	[455,522]	7	hSpCas9	negative selection	1323795
104859566	104859589	6	-	26627737	RPE1	viability after 15 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.2691390624372808	[1296]	[349,530]	1	hSpCas9	negative selection	1323796
104771974	104771997	6	-	26627737	RPE1	viability after 18 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.5510888671048374	[590]	[209,258]	3	hSpCas9	negative selection	1406105
104777200	104777223	6	+	26627737	RPE1	viability after 18 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.9637068266958726	[647]	[167,525]	6	hSpCas9	negative selection	1406106
104785161	104785184	6	+	26627737	RPE1	viability after 18 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.4265076096809166	[1146]	[328,508]	2	hSpCas9	negative selection	1406107
104852316	104852339	6	-	26627737	RPE1	viability after 18 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	1.3728162034723732	[633]	[241,657]	7	hSpCas9	negative selection	1406110
104859566	104859589	6	-	26627737	RPE1	viability after 18 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.2696264470303823	[1296]	[128,734]	1	hSpCas9	negative selection	1406111
104771974	104771997	6	-	26627737	HeLa	viability after 8 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.05717250177774874	[282]	[198,146,32]	0	hSpCas9	negative selection	1488420
104777200	104777223	6	+	26627737	HeLa	viability after 8 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.6006064010396731	[142]	[132,40,115]	5	hSpCas9	negative selection	1488421
104785161	104785184	6	+	26627737	HeLa	viability after 8 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.7301256042780965	[440]	[312,162,466]	6	hSpCas9	negative selection	1488422
104852316	104852339	6	-	26627737	HeLa	viability after 8 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.12782624352808736	[253]	[106,97,151]	1	hSpCas9	negative selection	1488425
104859566	104859589	6	-	26627737	HeLa	viability after 8 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	1.0447445073175619	[357]	[298,424,240]	7	hSpCas9	negative selection	1488426
104771974	104771997	6	-	26627737	HeLa	viability after 12 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.711947491363164	[282]	[37,82,90]	-6	hSpCas9	negative selection	1570735
104777200	104777223	6	+	26627737	HeLa	viability after 12 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.4374058520909438	[142]	[207,136,138]	8	hSpCas9	negative selection	1570736
104785161	104785184	6	+	26627737	HeLa	viability after 12 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.2785599540010031	[440]	[287,212,164]	2	hSpCas9	negative selection	1570737
104852316	104852339	6	-	26627737	HeLa	viability after 12 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.01691328132341441	[253]	[49,128,127]	0	hSpCas9	negative selection	1570740
104859566	104859589	6	-	26627737	HeLa	viability after 12 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.23851891938621633	[357]	[308,141,79]	2	hSpCas9	negative selection	1570741
104771974	104771997	6	-	26627737	HeLa	viability after 15 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.9679729294924782	[282]	[28,65,83]	-7	hSpCas9	negative selection	1653050
104777200	104777223	6	+	26627737	HeLa	viability after 15 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.1458582789174219	[142]	[187,40,158]	7	hSpCas9	negative selection	1653051
104785161	104785184	6	+	26627737	HeLa	viability after 15 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.4813744789618123	[440]	[284,281,178]	4	hSpCas9	negative selection	1653052
104852316	104852339	6	-	26627737	HeLa	viability after 15 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.06643635890341482	[253]	[95,104,94]	0	hSpCas9	negative selection	1653055
104859566	104859589	6	-	26627737	HeLa	viability after 15 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.26580136906266105	[357]	[161,210,150]	2	hSpCas9	negative selection	1653056
104771974	104771997	6	-	26627737	HeLa	viability after 18 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.8988567686727322	[282]	[23,55,83]	-7	hSpCas9	negative selection	1735365
104777200	104777223	6	+	26627737	HeLa	viability after 18 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.1418155482752166	[142]	[126,31,158]	7	hSpCas9	negative selection	1735366
104785161	104785184	6	+	26627737	HeLa	viability after 18 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.47832819357951106	[440]	[188,234,178]	4	hSpCas9	negative selection	1735367
104852316	104852339	6	-	26627737	HeLa	viability after 18 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.040880068025361926	[253]	[62,92,94]	0	hSpCas9	negative selection	1735370
104859566	104859589	6	-	26627737	HeLa	viability after 18 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.2476243372704326	[357]	[104,173,150]	2	hSpCas9	negative selection	1735371
104771974	104771997	6	-	26627737	HCT116	viability after 6 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.851037955030594	[451]	[79,16]	-5	hSpCas9	negative selection	1817680
104777200	104777223	6	+	26627737	HCT116	viability after 6 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.45259107665916126	[433]	[142,65]	2	hSpCas9	negative selection	1817681
104785161	104785184	6	+	26627737	HCT116	viability after 6 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	1.9931858622183936	[796]	[133,699]	8	hSpCas9	negative selection	1817682
104852316	104852339	6	-	26627737	HCT116	viability after 6 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.14969073008761036	[902]	[83,197]	0	hSpCas9	negative selection	1817685
104859566	104859589	6	-	26627737	HCT116	viability after 6 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	3.7817656706760925	[570]	[1106,1304]	9	hSpCas9	negative selection	1817686
104771974	104771997	6	-	26627737	HCT116	viability after 8 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.3129123423481365	[180]	[143,100,126]	3	hSpCas9	negative selection	1899995
104777200	104777223	6	+	26627737	HCT116	viability after 8 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.5748401075943067	[127]	[115,63,134]	6	hSpCas9	negative selection	1899996
104785161	104785184	6	+	26627737	HCT116	viability after 8 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	-0.0961396544076698	[538]	[275,317,239]	-1	hSpCas9	negative selection	1899997
104852316	104852339	6	-	26627737	HCT116	viability after 8 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.3777743935708652	[490]	[226,188,208]	-4	hSpCas9	negative selection	1900000
104859566	104859589	6	-	26627737	HCT116	viability after 8 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	1.0710285875797454	[211]	[185,285,262]	8	hSpCas9	negative selection	1900001
104771974	104771997	6	-	26627737	HCT116	viability after 9 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-1.373935530465721	[451]	[2,80]	-7	hSpCas9	negative selection	1982310
104777200	104777223	6	+	26627737	HCT116	viability after 9 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	-0.45945534931297005	[433]	[176,10]	-3	hSpCas9	negative selection	1982311
104785161	104785184	6	+	26627737	HCT116	viability after 9 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	-1.3335668016051945	[796]	[84,83]	-7	hSpCas9	negative selection	1982312
104852316	104852339	6	-	26627737	HCT116	viability after 9 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.2209264582639251	[902]	[318,250]	1	hSpCas9	negative selection	1982315
104859566	104859589	6	-	26627737	HCT116	viability after 9 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	1.6616373642513955	[570]	[640,356]	8	hSpCas9	negative selection	1982316
104771974	104771997	6	-	26627737	HCT116	viability after 12 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.3432151665544114	[180]	[189,82,81]	3	hSpCas9	negative selection	2064625
104777200	104777223	6	+	26627737	HCT116	viability after 12 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.172263333576873	[127]	[176,210,65]	8	hSpCas9	negative selection	2064626
104785161	104785184	6	+	26627737	HCT116	viability after 12 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.052231223229079804	[538]	[265,353,264]	0	hSpCas9	negative selection	2064627
104852316	104852339	6	-	26627737	HCT116	viability after 12 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.3574676173476573	[490]	[372,287,325]	3	hSpCas9	negative selection	2064630
104859566	104859589	6	-	26627737	HCT116	viability after 12 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	1.5362807162916805	[211]	[160,253,566]	9	hSpCas9	negative selection	2064631
104771974	104771997	6	-	26627737	HCT116	viability after 15 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.39188409852697953	[180]	[202,137,76]	4	hSpCas9	negative selection	2146940
104777200	104777223	6	+	26627737	HCT116	viability after 15 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.197764645660927	[127]	[254,144,116]	8	hSpCas9	negative selection	2146941
104785161	104785184	6	+	26627737	HCT116	viability after 15 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.11107630322770479	[538]	[313,311,373]	1	hSpCas9	negative selection	2146942
104852316	104852339	6	-	26627737	HCT116	viability after 15 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.11363297487744883	[490]	[315,244,227]	-1	hSpCas9	negative selection	2146945
104859566	104859589	6	-	26627737	HCT116	viability after 15 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	2.0741317505284877	[211]	[238,608,654]	9	hSpCas9	negative selection	2146946
104771974	104771997	6	-	26627737	HCT116	viability after 18 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.384481479757594	[180]	[134,102,104]	3	hSpCas9	negative selection	2229255
104777200	104777223	6	+	26627737	HCT116	viability after 18 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.0171217691617662	[127]	[120,175,72]	7	hSpCas9	negative selection	2229256
104785161	104785184	6	+	26627737	HCT116	viability after 18 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.4725396516407796	[538]	[307,440,328]	4	hSpCas9	negative selection	2229257
104852316	104852339	6	-	26627737	HCT116	viability after 18 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	1.1638466283754827	[490]	[854,283,469]	8	hSpCas9	negative selection	2229260
104859566	104859589	6	-	26627737	HCT116	viability after 18 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	2.134724758654335	[211]	[349,467,534]	9	hSpCas9	negative selection	2229261
104849141	104849164	6	-	24336569	HL60	viability	TTCATTTGGCAGCAAGAAATGGG	HACE1	ENSG00000085382	0.9645669410549884	[346]	[1432]	7	hSpCas9	negative selection	2268920
104849175	104849198	6	-	24336569	HL60	viability	CCTAACTATCAAGATATTTCAGG	HACE1	ENSG00000085382	0.7355195226264846	[255]	[901]	6	hSpCas9	negative selection	2268921
104849224	104849247	6	-	24336569	HL60	viability	TTGTGGATCGGTGGAATGCTTGG	HACE1	ENSG00000085382	0.8721767502197234	[418]	[1622]	7	hSpCas9	negative selection	2268922
104850943	104850966	6	-	24336569	HL60	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	1.9630637068212886	[326]	[2697]	9	hSpCas9	negative selection	2268923
104852316	104852339	6	-	24336569	HL60	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.649489116792436	[528]	[1755]	5	hSpCas9	negative selection	2268924
104852330	104852353	6	-	24336569	HL60	viability	TACATTAATGCCAATGGTTATGG	HACE1	ENSG00000085382	1.0763271451775611	[198]	[887]	8	hSpCas9	negative selection	2268925
104859562	104859585	6	+	24336569	HL60	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.037738606378094675	[237]	[516]	0	hSpCas9	negative selection	2268926
104859567	104859590	6	-	24336569	HL60	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	1.0682007507469529	[493]	[2191]	7	hSpCas9	negative selection	2268927
104859573	104859596	6	+	24336569	HL60	viability	GCAACTCCACGGTGCGCGCGCGG	HACE1	ENSG00000085382	0.6889466792422421	[694]	[2370]	6	hSpCas9	negative selection	2268928
104859627	104859650	6	-	24336569	HL60	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-1.3660170687172442	[742]	[609]	-8	hSpCas9	negative selection	2268929
104849141	104849164	6	-	24336569	KBM7	viability	TTCATTTGGCAGCAAGAAATGGG	HACE1	ENSG00000085382	0.6981773906458337	[514]	[2278]	6	hSpCas9	negative selection	2336097
104849175	104849198	6	-	24336569	KBM7	viability	CCTAACTATCAAGATATTTCAGG	HACE1	ENSG00000085382	-0.4921256355021446	[591]	[1147]	-4	hSpCas9	negative selection	2336098
104849224	104849247	6	-	24336569	KBM7	viability	TTGTGGATCGGTGGAATGCTTGG	HACE1	ENSG00000085382	0.03136135459727474	[620]	[1730]	0	hSpCas9	negative selection	2336099
104850943	104850966	6	-	24336569	KBM7	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.7511678301589995	[434]	[1996]	6	hSpCas9	negative selection	2336100
104852316	104852339	6	-	24336569	KBM7	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.23392955365763035	[732]	[1699]	-2	hSpCas9	negative selection	2336101
104852330	104852353	6	-	24336569	KBM7	viability	TACATTAATGCCAATGGTTATGG	HACE1	ENSG00000085382	0.10289492778698295	[253]	[743]	1	hSpCas9	negative selection	2336102
104859562	104859585	6	+	24336569	KBM7	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.7789293332597975	[149]	[701]	7	hSpCas9	negative selection	2336103
104859567	104859590	6	-	24336569	KBM7	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.708406613935556	[415]	[1853]	6	hSpCas9	negative selection	2336104
104859573	104859596	6	+	24336569	KBM7	viability	GCAACTCCACGGTGCGCGCGCGG	HACE1	ENSG00000085382	-0.23442744757885192	[715]	[1659]	-2	hSpCas9	negative selection	2336105
104859627	104859650	6	-	24336569	KBM7	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-3.7460005385516153	[486]	[98]	-9	hSpCas9	negative selection	2336106
104790709	104790732	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACTGCATTCCAGCCTAG	HACE1	ENSG00000085382	-2.365861438057623	[12,253]	[3,6]	-9	dCas9-VP64	positive selection	2395032
104769062	104769085	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCTCTGTCACTCAGGCTAG	HACE1	ENSG00000085382	-0.9680761470245136	[202,921]	[9,121]	-5	dCas9-VP64	positive selection	2407035
104808109	104808132	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAATCTCTGCCTCCTGG	HACE1	ENSG00000085382	0.009160240507729789	[175,457]	[15,128]	0	dCas9-VP64	positive selection	2425981
104733691	104733714	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATACAAAAATTAGCCAGGCGAAG	HACE1	ENSG00000085382	0.7667043826941231	[92,346]	[53,113]	3	dCas9-VP64	positive selection	2426027
104857880	104857903	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCTGCCTCCGGG	HACE1	ENSG00000085382	3.3241346106645673	[178,128]	[9,695]	8	dCas9-VP64	positive selection	2462071
104790709	104790732	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACTGCATTCCAGCCTAG	HACE1	ENSG00000085382	-1.4197804414947919	[336,129]	[25,29]	-9	dCas9-VP64	positive selection	2490287
104769062	104769085	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCTCTGTCACTCAGGCTAG	HACE1	ENSG00000085382	-0.6011121662635273	[131,74]	[29,13]	-6	dCas9-VP64	positive selection	2502290
104808109	104808132	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAATCTCTGCCTCCTGG	HACE1	ENSG00000085382	0.1118552473866502	[131,312]	[53,99]	0	dCas9-VP64	positive selection	2521236
104733691	104733714	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATACAAAAATTAGCCAGGCGAAG	HACE1	ENSG00000085382	0.15255249232697954	[139,139]	[73,28]	1	dCas9-VP64	positive selection	2521282
104857880	104857903	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCTGCCTCCGGG	HACE1	ENSG00000085382	-0.24751078726835885	[128,142]	[21,50]	-2	dCas9-VP64	positive selection	2557326
104849175	104849198	6	-	27260157	DLD1	viability	CCTAACTATCAAGATATTTCAGG	HACE1	ENSG00000085382	1.0910310572735	[]	[]	9	hSpCas9	negative selection	2575764
104859562	104859585	6	+	27260157	DLD1	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.739248262828641	[]	[]	8	hSpCas9	negative selection	2576939
104852330	104852353	6	-	27260157	DLD1	viability	TACATTAATGCCAATGGTTATGG	HACE1	ENSG00000085382	0.310383905743767	[]	[]	4	hSpCas9	negative selection	2578639
104796984	104797007	6	-	27260157	DLD1	viability	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	1.01970338223352	[]	[]	9	hSpCas9	negative selection	2582372
104859567	104859590	6	-	27260157	DLD1	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	-0.676814038440514	[]	[]	-5	hSpCas9	negative selection	2583116
104859573	104859596	6	+	27260157	DLD1	viability	GCAACTCCACGGTGCGCGCGCGG	HACE1	ENSG00000085382	-0.95509583534462	[]	[]	-7	hSpCas9	negative selection	2586663
104850943	104850966	6	-	27260157	DLD1	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.273101275091532	[]	[]	4	hSpCas9	negative selection	2606756
104849141	104849164	6	-	27260157	DLD1	viability	TTCATTTGGCAGCAAGAAATGGG	HACE1	ENSG00000085382	0.0739759152959586	[]	[]	3	hSpCas9	negative selection	2608621
104859627	104859650	6	-	27260157	DLD1	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-1.66781530802162	[]	[]	-8	hSpCas9	negative selection	2608680
104811329	104811352	6	+	27260157	DLD1	viability	GGAGTTGCTCCTGATACATTTGG	HACE1	ENSG00000085382	0.482738509226166	[]	[]	8	hSpCas9	negative selection	2614273
104849224	104849247	6	-	27260157	DLD1	viability	TTGTGGATCGGTGGAATGCTTGG	HACE1	ENSG00000085382	0.224589375632414	[]	[]	3	hSpCas9	negative selection	2622484
104811368	104811391	6	-	27260157	DLD1	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.166400658498345	[]	[]	3	hSpCas9	negative selection	2623678
104859626	104859649	6	+	27260157	DLD1	viability	TCCATCGCTCTCTCCATCCTCGG	HACE1	ENSG00000085382	0.395463521898064	[]	[]	4	hSpCas9	negative selection	2647885
104852316	104852339	6	-	27260157	DLD1	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.642880082970066	[]	[]	8	hSpCas9	negative selection	2649263
104849175	104849198	6	-	27260157	HT1080	viability	CCTAACTATCAAGATATTTCAGG	HACE1	ENSG00000085382	0.518050801187689	[]	[]	4	hSpCas9	negative selection	2651894
104859562	104859585	6	+	27260157	HT1080	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	1.38128859916383	[]	[]	9	hSpCas9	negative selection	2653069
104852330	104852353	6	-	27260157	HT1080	viability	TACATTAATGCCAATGGTTATGG	HACE1	ENSG00000085382	1.04810670315454	[]	[]	8	hSpCas9	negative selection	2654769
104796984	104797007	6	-	27260157	HT1080	viability	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	1.33508838462054	[]	[]	9	hSpCas9	negative selection	2658502
104859567	104859590	6	-	27260157	HT1080	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.555165562893625	[]	[]	5	hSpCas9	negative selection	2659246
104859573	104859596	6	+	27260157	HT1080	viability	GCAACTCCACGGTGCGCGCGCGG	HACE1	ENSG00000085382	0.129412719741985	[]	[]	1	hSpCas9	negative selection	2662793
104850943	104850966	6	-	27260157	HT1080	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.494768766042576	[]	[]	4	hSpCas9	negative selection	2682886
104849141	104849164	6	-	27260157	HT1080	viability	TTCATTTGGCAGCAAGAAATGGG	HACE1	ENSG00000085382	1.18646991477466	[]	[]	8	hSpCas9	negative selection	2684751
104859627	104859650	6	-	27260157	HT1080	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-2.12357358801907	[]	[]	-9	hSpCas9	negative selection	2684810
104811329	104811352	6	+	27260157	HT1080	viability	GGAGTTGCTCCTGATACATTTGG	HACE1	ENSG00000085382	-0.0698542243570786	[]	[]	0	hSpCas9	negative selection	2690403
104849224	104849247	6	-	27260157	HT1080	viability	TTGTGGATCGGTGGAATGCTTGG	HACE1	ENSG00000085382	0.966476648035411	[]	[]	7	hSpCas9	negative selection	2698614
104811368	104811391	6	-	27260157	HT1080	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.343362638383061	[]	[]	3	hSpCas9	negative selection	2699808
104859626	104859649	6	+	27260157	HT1080	viability	TCCATCGCTCTCTCCATCCTCGG	HACE1	ENSG00000085382	0.490745460680656	[]	[]	4	hSpCas9	negative selection	2724015
104852316	104852339	6	-	27260157	HT1080	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.0473367960701868	[]	[]	0	hSpCas9	negative selection	2725393
104849175	104849198	6	-	27260157	MKN45	viability	CCTAACTATCAAGATATTTCAGG	HACE1	ENSG00000085382	-0.343341667930552	[]	[]	-1	hSpCas9	negative selection	2728024
104859562	104859585	6	+	27260157	MKN45	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.000857307288420001	[]	[]	0	hSpCas9	negative selection	2729199
104852330	104852353	6	-	27260157	MKN45	viability	TACATTAATGCCAATGGTTATGG	HACE1	ENSG00000085382	0.642340552714511	[]	[]	7	hSpCas9	negative selection	2730899
104796984	104797007	6	-	27260157	MKN45	viability	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	-0.379694657715151	[]	[]	-1	hSpCas9	negative selection	2734632
104859567	104859590	6	-	27260157	MKN45	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	-0.404896424947596	[]	[]	-1	hSpCas9	negative selection	2735376
104859573	104859596	6	+	27260157	MKN45	viability	GCAACTCCACGGTGCGCGCGCGG	HACE1	ENSG00000085382	-0.000987088089725989	[]	[]	0	hSpCas9	negative selection	2738923
104850943	104850966	6	-	27260157	MKN45	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.78093076777339	[]	[]	7	hSpCas9	negative selection	2759016
104849141	104849164	6	-	27260157	MKN45	viability	TTCATTTGGCAGCAAGAAATGGG	HACE1	ENSG00000085382	0.444985881246708	[]	[]	6	hSpCas9	negative selection	2760881
104859627	104859650	6	-	27260157	MKN45	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-0.604543660586855	[]	[]	-6	hSpCas9	negative selection	2760940
104811329	104811352	6	+	27260157	MKN45	viability	GGAGTTGCTCCTGATACATTTGG	HACE1	ENSG00000085382	0.671411209482323	[]	[]	7	hSpCas9	negative selection	2766533
104849224	104849247	6	-	27260157	MKN45	viability	TTGTGGATCGGTGGAATGCTTGG	HACE1	ENSG00000085382	-0.457163028737793	[]	[]	-6	hSpCas9	negative selection	2774744
104811368	104811391	6	-	27260157	MKN45	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	-1.41585445866591	[]	[]	-8	hSpCas9	negative selection	2775938
104859626	104859649	6	+	27260157	MKN45	viability	TCCATCGCTCTCTCCATCCTCGG	HACE1	ENSG00000085382	-0.0691553460997661	[]	[]	0	hSpCas9	negative selection	2800145
104852316	104852339	6	-	27260157	MKN45	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.154244508730729	[]	[]	0	hSpCas9	negative selection	2801523
104849175	104849198	6	-	27260157	RKO	viability	CCTAACTATCAAGATATTTCAGG	HACE1	ENSG00000085382	-0.0531872980845572	[]	[]	0	hSpCas9	negative selection	2804154
104859562	104859585	6	+	27260157	RKO	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.00362143880176134	[]	[]	0	hSpCas9	negative selection	2805329
104852330	104852353	6	-	27260157	RKO	viability	TACATTAATGCCAATGGTTATGG	HACE1	ENSG00000085382	0.819216298425137	[]	[]	8	hSpCas9	negative selection	2807029
104796984	104797007	6	-	27260157	RKO	viability	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	-0.357262052270229	[]	[]	-6	hSpCas9	negative selection	2810762
104859567	104859590	6	-	27260157	RKO	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	-0.511233019155227	[]	[]	-6	hSpCas9	negative selection	2811506
104859573	104859596	6	+	27260157	RKO	viability	GCAACTCCACGGTGCGCGCGCGG	HACE1	ENSG00000085382	-1.20960467891763	[]	[]	-8	hSpCas9	negative selection	2815053
104850943	104850966	6	-	27260157	RKO	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.290594710855451	[]	[]	1	hSpCas9	negative selection	2835146
104849141	104849164	6	-	27260157	RKO	viability	TTCATTTGGCAGCAAGAAATGGG	HACE1	ENSG00000085382	-0.143440600485565	[]	[]	0	hSpCas9	negative selection	2837011
104859627	104859650	6	-	27260157	RKO	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-1.66807763613775	[]	[]	-9	hSpCas9	negative selection	2837070
104811329	104811352	6	+	27260157	RKO	viability	GGAGTTGCTCCTGATACATTTGG	HACE1	ENSG00000085382	-0.352226963304703	[]	[]	-6	hSpCas9	negative selection	2842663
104849224	104849247	6	-	27260157	RKO	viability	TTGTGGATCGGTGGAATGCTTGG	HACE1	ENSG00000085382	0.409569635550122	[]	[]	2	hSpCas9	negative selection	2850874
104811368	104811391	6	-	27260157	RKO	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.0772974868869521	[]	[]	0	hSpCas9	negative selection	2852068
104859626	104859649	6	+	27260157	RKO	viability	TCCATCGCTCTCTCCATCCTCGG	HACE1	ENSG00000085382	0.00111057767311349	[]	[]	0	hSpCas9	negative selection	2876275
104852316	104852339	6	-	27260157	RKO	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.420130412788982	[]	[]	-6	hSpCas9	negative selection	2877653
104849175	104849198	6	-	27260157	SF268	viability	CCTAACTATCAAGATATTTCAGG	HACE1	ENSG00000085382	-0.197817864412106	[]	[]	-1	hSpCas9	negative selection	2880284
104859562	104859585	6	+	27260157	SF268	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.565591225560444	[]	[]	8	hSpCas9	negative selection	2881459
104852330	104852353	6	-	27260157	SF268	viability	TACATTAATGCCAATGGTTATGG	HACE1	ENSG00000085382	0.149329422217805	[]	[]	0	hSpCas9	negative selection	2883159
104796984	104797007	6	-	27260157	SF268	viability	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	0.163779838418229	[]	[]	0	hSpCas9	negative selection	2886892
104859567	104859590	6	-	27260157	SF268	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	-0.335061643908936	[]	[]	-3	hSpCas9	negative selection	2887636
104859573	104859596	6	+	27260157	SF268	viability	GCAACTCCACGGTGCGCGCGCGG	HACE1	ENSG00000085382	-0.200706674591141	[]	[]	-1	hSpCas9	negative selection	2891183
104850943	104850966	6	-	27260157	SF268	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.344025482956171	[]	[]	4	hSpCas9	negative selection	2911276
104849141	104849164	6	-	27260157	SF268	viability	TTCATTTGGCAGCAAGAAATGGG	HACE1	ENSG00000085382	-0.121036263161017	[]	[]	-1	hSpCas9	negative selection	2913141
104859627	104859650	6	-	27260157	SF268	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-2.51376479750474	[]	[]	-9	hSpCas9	negative selection	2913200
104811329	104811352	6	+	27260157	SF268	viability	GGAGTTGCTCCTGATACATTTGG	HACE1	ENSG00000085382	0.722167206021035	[]	[]	8	hSpCas9	negative selection	2918793
104849224	104849247	6	-	27260157	SF268	viability	TTGTGGATCGGTGGAATGCTTGG	HACE1	ENSG00000085382	0.751900647390496	[]	[]	8	hSpCas9	negative selection	2927004
104811368	104811391	6	-	27260157	SF268	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.0602027121683919	[]	[]	0	hSpCas9	negative selection	2928198
104859626	104859649	6	+	27260157	SF268	viability	TCCATCGCTCTCTCCATCCTCGG	HACE1	ENSG00000085382	0.507583925470068	[]	[]	7	hSpCas9	negative selection	2952405
104852316	104852339	6	-	27260157	SF268	viability	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.238254349559775	[]	[]	3	hSpCas9	negative selection	2953783
104796693	104796716	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAATAGTCTGAAAAAGCCTCGG	HACE1	ENSG00000085382	-0.3236886495067716	[5,4]	[4,1]	-4	hSpCas9	positive selection	2992633
104796984	104797007	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	0.07106117789118574	[2,2]	[3,1]	1	hSpCas9	positive selection	2992634
104811368	104811391	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	-0.5022404987103866	[2,2]	[2,0]	-6	hSpCas9	positive selection	2992635
104785145	104785168	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATAGCTCCCAGGTCCTGGAGG	HACE1	ENSG00000085382	0.36458097476009116	[4,4]	[5,4]	7	hSpCas9	positive selection	2992636
104796693	104796716	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAATAGTCTGAAAAAGCCTCGG	HACE1	ENSG00000085382	0.26631826231316175	[5,5]	[5,3]	5	hSpCas9	positive selection	3060491
104796984	104797007	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	0.39633873294703376	[2,2]	[3,1]	7	hSpCas9	positive selection	3060492
104811368	104811391	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	-0.49259820780007135	[2,2]	[2,0]	-7	hSpCas9	positive selection	3060493
104785145	104785168	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATAGCTCCCAGGTCCTGGAGG	HACE1	ENSG00000085382	-0.11080728155590963	[4,4]	[3,2]	-2	hSpCas9	positive selection	3060494
104859591	104859614		+	24336571	A375	resistance to PLX after 7 days	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.14019741465216473	[2,2]	[2,2]	4	hSpCas9	positive selection	3118365
104852320	104852343		+	24336571	A375	resistance to PLX after 7 days	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.015353005752623938	[13,16]	[17,13]	0	hSpCas9	positive selection	3118366
104859591	104859614		+	24336571	A375	resistance to PLX after 14 days	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.47331534844308254	[3,2]	[1,1]	4	hSpCas9	positive selection	3176158
104852320	104852343		+	24336571	A375	resistance to PLX after 14 days	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.48343514237129404	[9,14]	[2,3]	-6	hSpCas9	positive selection	3176159
104859591	104859614		+	24336571	A375	viability after 7 days	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.4376187929743822	[1]	[2,2]	6	hSpCas9	negative selection	3233951
104852320	104852343		+	24336571	A375	viability after 7 days	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.04696320742654825	[16]	[13,16]	0	hSpCas9	negative selection	3233952
104859591	104859614		+	24336571	A375	viability after 14 days	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.5397086570362251	[1]	[3,2]	7	hSpCas9	negative selection	3291744
104852320	104852343		+	24336571	A375	viability after 14 days	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.32629107587449907	[16]	[9,14]	-4	hSpCas9	negative selection	3291745
104859591	104859614	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	5.094753876290597	[0,7]	[0,0]	9	hSpCas9	positive selection	3352931
104852320	104852343	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-1.6941108894826342	[502,486]	[0,0]	-9	hSpCas9	positive selection	3352932
104859562	104859585	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	1.2803456643821223	[60,64]	[0,0]	5	hSpCas9	positive selection	3352933
104850943	104850966	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	-1.2345268848838393	[359,359]	[0,0]	-7	hSpCas9	positive selection	3372122
104852336	104852359	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	1.107579091941153	[70,70]	[0,0]	5	hSpCas9	positive selection	3372123
104859579	104859602	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	3.087401210003523	[17,17]	[0,0]	8	hSpCas9	positive selection	3372124
104796692	104796715	6	+	26780180	HT29	viability (Avana library 4 designs)	ATAATAGTCTGAAAAAGCCTCGG	HACE1	ENSG00000085382	0.285857891824191	[]	[]	1	hSpCas9	negative selection	3429884
104796984	104797007	6	-	26780180	HT29	viability (Avana library 4 designs)	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	1.5175875184294	[]	[]	6	hSpCas9	negative selection	3429885
104811368	104811391	6	-	26780180	HT29	viability (Avana library 4 designs)	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	1.64540401675315	[]	[]	6	hSpCas9	negative selection	3429886
104785144	104785167	6	+	26780180	HT29	viability (Avana library 4 designs)	TCATAGCTCCCAGGTCCTGGAGG	HACE1	ENSG00000085382	-0.764953565384945	[]	[]	-9	hSpCas9	negative selection	3429887
104796984	104797007	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	-0.923366929954883	[]	[]	-1	hSpCas9	negative selection	3514777
104796692	104796715	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAATAGTCTGAAAAAGCCTCGG	HACE1	ENSG00000085382	-7.00165702782108	[]	[]	-6	hSpCas9	negative selection	3514778
104811368	104811391	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	3.46259870828753	[]	[]	5	hSpCas9	negative selection	3514779
104785144	104785167	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCATAGCTCCCAGGTCCTGGAGG	HACE1	ENSG00000085382	2.94000389349623	[]	[]	4	hSpCas9	negative selection	3514780
104785041	104785064	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTATTTCTATGACAGCTAACCGG	HACE1	ENSG00000085382	-8.83012592750086	[]	[]	-7	hSpCas9	negative selection	3514781
104859566	104859589	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	2.63526066244373	[]	[]	4	hSpCas9	negative selection	3514782
104796984	104797007	6	-	26780180	A375	viability (Avana lentiGuide)	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	-6.09417971810196	[]	[]	-9	hSpCas9	negative selection	3623436
104796692	104796715	6	+	26780180	A375	viability (Avana lentiGuide)	ATAATAGTCTGAAAAAGCCTCGG	HACE1	ENSG00000085382	-2.3379148070272	[]	[]	-4	hSpCas9	negative selection	3623437
104811368	104811391	6	-	26780180	A375	viability (Avana lentiGuide)	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	-0.906890842981946	[]	[]	-1	hSpCas9	negative selection	3623438
104785144	104785167	6	+	26780180	A375	viability (Avana lentiGuide)	TCATAGCTCCCAGGTCCTGGAGG	HACE1	ENSG00000085382	-3.36102149239584	[]	[]	-6	hSpCas9	negative selection	3623439
104785041	104785064	6	-	26780180	A375	viability (Avana lentiGuide)	TTATTTCTATGACAGCTAACCGG	HACE1	ENSG00000085382	-0.0507610453564202	[]	[]	0	hSpCas9	negative selection	3623440
104859566	104859589	6	-	26780180	A375	viability (Avana lentiGuide)	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	2.38114771751698	[]	[]	2	hSpCas9	negative selection	3623441
104796984	104797007	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	-0.42116918049025187	[5]	[3,3]	-6	hSpCas9	positive selection	3732095
104796692	104796715	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAATAGTCTGAAAAAGCCTCGG	HACE1	ENSG00000085382	-0.3988302231588046	[8]	[6,5]	-5	hSpCas9	positive selection	3732096
104811368	104811391	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.1807639849990081	[4]	[4,5]	5	hSpCas9	positive selection	3732097
104785144	104785167	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATAGCTCCCAGGTCCTGGAGG	HACE1	ENSG00000085382	0.24347576323619513	[6]	[7,6]	7	hSpCas9	positive selection	3732098
104785041	104785064	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATTTCTATGACAGCTAACCGG	HACE1	ENSG00000085382	-1.1314545765136617	[7]	[2,3]	-9	hSpCas9	positive selection	3732099
104859566	104859589	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.2943601409743935	[3]	[4,5]	8	hSpCas9	positive selection	3732100
104796984	104797007	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAGATCCTACTATTACGAGG	HACE1	ENSG00000085382	0.09914332998271631	[4]	[3,4]	2	hSpCas9	positive selection	3840702
104796692	104796715	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAATAGTCTGAAAAAGCCTCGG	HACE1	ENSG00000085382	0.11167381531981713	[6]	[6,6]	2	hSpCas9	positive selection	3840703
104811368	104811391	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	-0.7049815219231397	[4]	[2,1]	-7	hSpCas9	positive selection	3840704
104785144	104785167	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATAGCTCCCAGGTCCTGGAGG	HACE1	ENSG00000085382	0.3104801315522141	[6]	[6,6]	8	hSpCas9	positive selection	3840705
104785041	104785064	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATTTCTATGACAGCTAACCGG	HACE1	ENSG00000085382	0.3432333081032343	[5]	[5,5]	8	hSpCas9	positive selection	3840706
104859566	104859589	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.15561779505680545	[4]	[2,3]	-2	hSpCas9	positive selection	3840707
104859591	104859614	6	+	26780180	A375	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.145539425849391	[]	[]	0	hSpCas9	negative selection	3946768
104859562	104859585	6	+	26780180	A375	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	1.21692650748783	[]	[]	6	hSpCas9	negative selection	3946769
104859579	104859602	6	-	26780180	A375	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.19316420272438	[]	[]	0	hSpCas9	negative selection	3946770
104852320	104852343	6	+	26780180	A375	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.131530923791789	[]	[]	0	hSpCas9	negative selection	3946771
104852336	104852359	6	-	26780180	A375	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.898900884241412	[]	[]	4	hSpCas9	negative selection	3946772
104850943	104850966	6	-	26780180	A375	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	1.50415411576032	[]	[]	8	hSpCas9	negative selection	3946773
104859591	104859614	6	+	26780180	HT29	viability (GeCKOv2 library)	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.226709646414537	[]	[]	0	hSpCas9	negative selection	4054734
104859562	104859585	6	+	26780180	HT29	viability (GeCKOv2 library)	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.545220832139531	[]	[]	1	hSpCas9	negative selection	4054735
104859579	104859602	6	-	26780180	HT29	viability (GeCKOv2 library)	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.34370248931378	[]	[]	0	hSpCas9	negative selection	4054736
104852320	104852343	6	+	26780180	HT29	viability (GeCKOv2 library)	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.0700517400817255	[]	[]	0	hSpCas9	negative selection	4054737
104852336	104852359	6	-	26780180	HT29	viability (GeCKOv2 library)	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.39265601502102	[]	[]	1	hSpCas9	negative selection	4054738
104850943	104850966	6	-	26780180	HT29	viability (GeCKOv2 library)	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	1.0782699669412	[]	[]	5	hSpCas9	negative selection	4054739
104859591	104859614	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.393303741132366	[0]	[1,0]	8	hSpCas9	positive selection	4141782
104852320	104852343	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.25215624117564406	[3]	[1,1]	-6	hSpCas9	positive selection	4141783
104859591	104859614	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.7939945187344093	[0]	[0,0,0,0]	5	hSpCas9	positive selection	4205804
104852320	104852343	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.22407593327954559	[2]	[3,0,1,0]	1	hSpCas9	positive selection	4205805
104859591	104859614	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.5579577502838988	[0]	[0,0]	9	hSpCas9	positive selection	4274478
104852320	104852343	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.052885723377958826	[4]	[5,2]	1	hSpCas9	positive selection	4274479
104859562	104859585	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.9041692704642166	[2]	[3,4]	9	hSpCas9	positive selection	4274480
104781987	104782010	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.7784304134879724	[2]	[1,0]	-9	hSpCas9	positive selection	4315492
104850943	104850966	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.5733097222305419	[3]	[4,4]	9	hSpCas9	positive selection	4338739
104852336	104852359	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.2556139033065251	[1]	[2,0]	5	hSpCas9	positive selection	4338740
104859579	104859602	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.5696447012749882	[0]	[2,0]	9	hSpCas9	positive selection	4338741
104785284	104785306	6	-	27760321	OCIAML3	viability	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	-0.6652900467114548	[272,206]	[73,173]	-6	hSpCas9	negative selection	4406103
104791577	104791599	6	-	27760321	OCIAML3	viability	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	1.2227524834348016	[156,154]	[321,237]	9	hSpCas9	negative selection	4406104
104796709	104796731	6	-	27760321	OCIAML3	viability	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	0.09403155465300816	[108,60]	[82,51]	1	hSpCas9	negative selection	4406105
104852316	104852338	6	-	27760321	OCIAML3	viability	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.017140226308111302	[459,461]	[271,468]	0	hSpCas9	negative selection	4406106
104785284	104785306	6	-	27760321	OCIAML2	viability	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.16358572543569083	[272,206]	[172,271]	2	hSpCas9	negative selection	4489566
104791577	104791599	6	-	27760321	OCIAML2	viability	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	0.37235115121940243	[156,154]	[149,181]	5	hSpCas9	negative selection	4489567
104796709	104796731	6	-	27760321	OCIAML2	viability	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	0.23573599721334793	[108,60]	[68,92]	3	hSpCas9	negative selection	4489568
104852316	104852338	6	-	27760321	OCIAML2	viability	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.011460032112796809	[459,461]	[346,416]	0	hSpCas9	negative selection	4489569
104785284	104785306	6	-	27760321	MV411	viability	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.9886547397777133	[272,206]	[499,28]	7	hSpCas9	negative selection	4573029
104791577	104791599	6	-	27760321	MV411	viability	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	0.6127507235372991	[156,154]	[222,59]	4	hSpCas9	negative selection	4573030
104796709	104796731	6	-	27760321	MV411	viability	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	-1.5339290949051145	[108,60]	[0,45]	-7	hSpCas9	negative selection	4573031
104852316	104852338	6	-	27760321	MV411	viability	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	1.3921759362107096	[459,461]	[1100,350]	8	hSpCas9	negative selection	4573032
104785284	104785306	6	-	27760321	HL60	viability	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.17652466903289554	[272,206]	[212,226]	2	hSpCas9	negative selection	4656492
104791577	104791599	6	-	27760321	HL60	viability	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	0.8191087255619748	[156,154]	[256,191]	8	hSpCas9	negative selection	4656493
104796709	104796731	6	-	27760321	HL60	viability	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	0.5884410073803861	[108,60]	[79,125]	7	hSpCas9	negative selection	4656494
104852316	104852338	6	-	27760321	HL60	viability	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.41420184795929743	[459,461]	[252,315]	-4	hSpCas9	negative selection	4656495
104785284	104785306	6	-	27760321	HT1080	viability	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	3.772129063764743	[206,161]	[863,1157]	9	hSpCas9	negative selection	4739955
104791577	104791599	6	-	27760321	HT1080	viability	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	1.3039228215490308	[154,120]	[224,37]	7	hSpCas9	negative selection	4739956
104796709	104796731	6	-	27760321	HT1080	viability	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	3.1034816321916523	[60,47]	[211,158]	9	hSpCas9	negative selection	4739957
104852316	104852338	6	-	27760321	HT1080	viability	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	3.454094336697843	[461,360]	[1705,1895]	9	hSpCas9	negative selection	4739958
104785284	104785306	6	-	27760321	HT29	viability after 7 days	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.17534316559959873	[206,161]	[276,238,287]	2	hSpCas9	negative selection	4823418
104791577	104791599	6	-	27760321	HT29	viability after 7 days	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	-1.0822222548644072	[154,120]	[144,30,83]	-8	hSpCas9	negative selection	4823419
104796709	104796731	6	-	27760321	HT29	viability after 7 days	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	0.040384060091346985	[60,47]	[98,79,41]	0	hSpCas9	negative selection	4823420
104852316	104852338	6	-	27760321	HT29	viability after 7 days	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.6405325084742508	[461,360]	[361,288,368]	-7	hSpCas9	negative selection	4823421
104785284	104785306	6	-	27760321	HT29	viability after 25 days	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	-0.3270358563069711	[206,161]	[96,187,229]	-3	hSpCas9	negative selection	4906881
104791577	104791599	6	-	27760321	HT29	viability after 25 days	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	-0.444969920051548	[154,120]	[41,116,201]	-4	hSpCas9	negative selection	4906882
104796709	104796731	6	-	27760321	HT29	viability after 25 days	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	0.09365784806596267	[60,47]	[37,80,83]	0	hSpCas9	negative selection	4906883
104852316	104852338	6	-	27760321	HT29	viability after 25 days	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.035164614115388265	[461,360]	[341,567,550]	0	hSpCas9	negative selection	4906884
104785284	104785306	6	-	27760321	HT29	viability after 22 days	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.271816338598726	[206,161]	[341,209,217]	3	hSpCas9	negative selection	4990344
104791577	104791599	6	-	27760321	HT29	viability after 22 days	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	0.09093363806859633	[154,120]	[87,144,279]	0	hSpCas9	negative selection	4990345
104796709	104796731	6	-	27760321	HT29	viability after 22 days	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	0.9402260730858358	[60,47]	[18,185,160]	9	hSpCas9	negative selection	4990346
104852316	104852338	6	-	27760321	HT29	viability after 22 days	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.057600762352168156	[461,360]	[355,650,481]	0	hSpCas9	negative selection	4990347
104785284	104785306	6	-	27760321	HT29	viability after 19 days	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.07079971766461435	[206,161]	[341,155,180]	0	hSpCas9	negative selection	5073807
104791577	104791599	6	-	27760321	HT29	viability after 19 days	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	-1.0249080135749815	[154,120]	[25,9,186]	-6	hSpCas9	negative selection	5073808
104796709	104796731	6	-	27760321	HT29	viability after 19 days	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	-2.406337178419981	[60,47]	[14,18,1]	-8	hSpCas9	negative selection	5073809
104852316	104852338	6	-	27760321	HT29	viability after 19 days	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.06121509262283081	[461,360]	[482,412,459]	0	hSpCas9	negative selection	5073810
104785284	104785306	6	-	27760321	HT29	viability after 16 days	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.1778495939186826	[206,161]	[239,240,219]	2	hSpCas9	negative selection	5157270
104791577	104791599	6	-	27760321	HT29	viability after 16 days	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	-0.36680944370059154	[154,120]	[188,70,106]	-4	hSpCas9	negative selection	5157271
104796709	104796731	6	-	27760321	HT29	viability after 16 days	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	-0.12323648819741839	[60,47]	[105,7,59]	-1	hSpCas9	negative selection	5157272
104852316	104852338	6	-	27760321	HT29	viability after 16 days	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-1.0319116599785134	[461,360]	[228,295,148]	-7	hSpCas9	negative selection	5157273
104785284	104785306	6	-	27760321	HT29	viability after 13 days	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	-0.017605387141237827	[206,161]	[122,374,140]	0	hSpCas9	negative selection	5240733
104791577	104791599	6	-	27760321	HT29	viability after 13 days	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	-0.5956851803005174	[154,120]	[46,165,104]	-6	hSpCas9	negative selection	5240734
104796709	104796731	6	-	27760321	HT29	viability after 13 days	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	-0.4569819128556616	[60,47]	[17,85,34]	-5	hSpCas9	negative selection	5240735
104852316	104852338	6	-	27760321	HT29	viability after 13 days	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.15800099453558406	[461,360]	[516,399,369]	-2	hSpCas9	negative selection	5240736
104785284	104785306	6	-	27760321	HT29	viability after 10 days	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	0.055318396408387316	[206,161]	[337,251,130]	0	hSpCas9	negative selection	5324196
104791577	104791599	6	-	27760321	HT29	viability after 10 days	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	-1.1889881251887093	[154,120]	[71,82,71]	-8	hSpCas9	negative selection	5324197
104796709	104796731	6	-	27760321	HT29	viability after 10 days	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	-0.10400026275505381	[60,47]	[73,37,76]	-1	hSpCas9	negative selection	5324198
104852316	104852338	6	-	27760321	HT29	viability after 10 days	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	-0.11049191886935365	[461,360]	[677,390,358]	-1	hSpCas9	negative selection	5324199
104785284	104785306	6	-	27760321	MOLM13	viability	TTGGCACTCGTTAGATGAATGG	HACE1	ENSG00000085382	-0.10167123173284798	[272,206]	[115,132]	0	hSpCas9	negative selection	5407659
104791577	104791599	6	-	27760321	MOLM13	viability	TTTGTCACGTCTTTCGAATTGG	HACE1	ENSG00000085382	-1.8290841003850078	[156,154]	[26,22]	-7	hSpCas9	negative selection	5407660
104796709	104796731	6	-	27760321	MOLM13	viability	ATTAATTCAATATCACCCGAGG	HACE1	ENSG00000085382	1.1052080885317965	[108,60]	[112,90]	7	hSpCas9	negative selection	5407661
104852316	104852338	6	-	27760321	MOLM13	viability	GGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.7399584732390462	[459,461]	[591,302]	5	hSpCas9	negative selection	5407662
104859828	104859851	6	-	27661255	K562	viability	GCGGGTGTACTGTAGGTGGTCGG	HACE1	ENSG00000085382	0.15948477223201762	[511,473]	[501,387]	5	dCas9-KRAB	negative selection	5483998
104859832	104859855	6	-	27661255	K562	viability	GGCGGCGGGTGTACTGTAGGTGG	HACE1	ENSG00000085382	0.17492375845425923	[607,626]	[643,481]	6	dCas9-KRAB	negative selection	5483999
104859835	104859858	6	-	27661255	K562	viability	GGCGGCGGCGGGTGTACTGTAGG	HACE1	ENSG00000085382	0.01262200247949613	[643,536]	[505,452]	0	dCas9-KRAB	negative selection	5484000
104859591	104859614	6	+	27260156	BXPC3	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.31273849886266003	[9]	[8,0,32,9]	6	hSpCas9	negative selection	5546938
104852320	104852343	6	+	27260156	BXPC3	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.07621639853084461	[1792]	[1638,2030,2010,2282]	1	hSpCas9	negative selection	5546939
104859562	104859585	6	+	27260156	BXPC3	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.41952735657708895	[265]	[381,294,498,306]	8	hSpCas9	negative selection	5546940
104781987	104782010	6	+	27260156	BXPC3	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.5825844030673897	[458]	[430,244,316,272]	-8	hSpCas9	negative selection	5587952
104850943	104850966	6	-	27260156	BXPC3	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	-0.09583035038352106	[865]	[840,723,803,1045]	-2	hSpCas9	negative selection	5611199
104852336	104852359	6	-	27260156	BXPC3	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.23989285674937855	[108]	[128,143,148,112]	5	hSpCas9	negative selection	5611200
104859579	104859602	6	-	27260156	BXPC3	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.053556262822028966	[42]	[48,60,26,47]	1	hSpCas9	negative selection	5611201
104859591	104859614	6	+	27260156	A673	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-2.2760705455700734	[9]	[2,2,0,2]	-9	hSpCas9	negative selection	5668189
104852320	104852343	6	+	27260156	A673	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.005767778707733928	[1792]	[2461,2167,2073,1961]	0	hSpCas9	negative selection	5668190
104859562	104859585	6	+	27260156	A673	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.5406755118724265	[265]	[520,401,470,471]	9	hSpCas9	negative selection	5668191
104781987	104782010	6	+	27260156	A673	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.43685275446023103	[458]	[387,410,365,463]	-8	hSpCas9	negative selection	5709203
104850943	104850966	6	-	27260156	A673	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.019695832151732096	[865]	[923,1094,958,1230]	0	hSpCas9	negative selection	5732450
104852336	104852359	6	-	27260156	A673	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.1673369273719305	[108]	[173,139,130,145]	4	hSpCas9	negative selection	5732451
104859579	104859602	6	-	27260156	A673	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.5567475087766445	[42]	[95,53,72,83]	9	hSpCas9	negative selection	5732452
104859591	104859614	6	+	27260156	A375	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-2.0793623522681415	[9]	[0,0,7,0]	-9	hSpCas9	negative selection	5789440
104852320	104852343	6	+	27260156	A375	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.11689672110371174	[1792]	[1720,1766,2532,1699]	-2	hSpCas9	negative selection	5789441
104859562	104859585	6	+	27260156	A375	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.5509874168034283	[265]	[410,486,607,331]	7	hSpCas9	negative selection	5789442
104781987	104782010	6	+	27260156	A375	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-2.1673574811805314	[458]	[94,145,78,155]	-9	hSpCas9	negative selection	5830454
104850943	104850966	6	-	27260156	A375	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.09759603069710043	[865]	[1038,1080,1127,1076]	1	hSpCas9	negative selection	5853701
104852336	104852359	6	-	27260156	A375	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.40295599616080313	[108]	[112,197,331,47]	6	hSpCas9	negative selection	5853702
104859579	104859602	6	-	27260156	A375	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.481947470976996	[42]	[14,72,45,16]	-6	hSpCas9	negative selection	5853703
104859591	104859614	6	+	27260156	COLO741	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-1.4499830750694587	[9]	[0,11,0]	-9	hSpCas9	negative selection	5910691
104852320	104852343	6	+	27260156	COLO741	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.00046196104097617763	[1792]	[2750,2396,1797]	0	hSpCas9	negative selection	5910692
104859562	104859585	6	+	27260156	COLO741	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	-0.1774641210849497	[265]	[271,359,268]	-4	hSpCas9	negative selection	5910693
104781987	104782010	6	+	27260156	COLO741	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.5872393009679945	[458]	[462,291,418]	-8	hSpCas9	negative selection	5951705
104850943	104850966	6	-	27260156	COLO741	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	-0.22037002655515114	[865]	[979,1133,750]	-5	hSpCas9	negative selection	5974952
104852336	104852359	6	-	27260156	COLO741	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.06370106809150577	[108]	[137,169,128]	1	hSpCas9	negative selection	5974953
104859579	104859602	6	-	27260156	COLO741	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.6749856695422998	[42]	[110,25,124]	9	hSpCas9	negative selection	5974954
104859591	104859614	6	+	27260156	CAL120	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.20947552416540116	[9]	[20,11,0]	-3	hSpCas9	negative selection	6031942
104852320	104852343	6	+	27260156	CAL120	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.1537256537889755	[1792]	[2625,1560,1923]	-2	hSpCas9	negative selection	6031943
104859562	104859585	6	+	27260156	CAL120	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.5470824124475049	[265]	[604,380,482]	7	hSpCas9	negative selection	6031944
104781987	104782010	6	+	27260156	CAL120	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.4923664477976866	[458]	[415,133,92]	-9	hSpCas9	negative selection	6072956
104850943	104850966	6	-	27260156	CAL120	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.15442577567223525	[865]	[1564,1073,1016]	2	hSpCas9	negative selection	6096203
104852336	104852359	6	-	27260156	CAL120	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.3790730153597359	[108]	[172,200,154]	5	hSpCas9	negative selection	6096204
104859579	104859602	6	-	27260156	CAL120	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.3494766747552238	[42]	[63,78,60]	5	hSpCas9	negative selection	6096205
104859591	104859614	6	+	27260156	CADOES1	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	1.2817926358815468	[9]	[0,0,0,89]	9	hSpCas9	negative selection	6153193
104852320	104852343	6	+	27260156	CADOES1	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.20412333554685813	[1792]	[1647,1209,1287,1650]	-4	hSpCas9	negative selection	6153194
104859562	104859585	6	+	27260156	CADOES1	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.1872493728949559	[265]	[322,238,270,293]	3	hSpCas9	negative selection	6153195
104781987	104782010	6	+	27260156	CADOES1	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.7187101732604496	[458]	[158,346,247,284]	-8	hSpCas9	negative selection	6194207
104850943	104850966	6	-	27260156	CADOES1	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.1719729074027746	[865]	[947,781,945,954]	3	hSpCas9	negative selection	6217454
104852336	104852359	6	-	27260156	CADOES1	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.5812433199750546	[108]	[98,202,176,126]	8	hSpCas9	negative selection	6217455
104859579	104859602	6	-	27260156	CADOES1	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.023883172673830444	[42]	[45,49,30,29]	0	hSpCas9	negative selection	6217456
104859591	104859614	6	+	27260156	EWS502	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.6431167555166164	[9]	[0,3,0,22]	-8	hSpCas9	negative selection	6274444
104852320	104852343	6	+	27260156	EWS502	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.30714182937888057	[1792]	[1363,1420,1625,1765]	-5	hSpCas9	negative selection	6274445
104859562	104859585	6	+	27260156	EWS502	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.3989351987514275	[265]	[254,408,484,347]	7	hSpCas9	negative selection	6274446
104781987	104782010	6	+	27260156	EWS502	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.7403094310241651	[458]	[98,224,104,154]	-9	hSpCas9	negative selection	6315458
104850943	104850966	6	-	27260156	EWS502	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.2479030103220009	[865]	[1266,626,1270,1194]	4	hSpCas9	negative selection	6338705
104852336	104852359	6	-	27260156	EWS502	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.3038081230951175	[108]	[82,79,164,259]	5	hSpCas9	negative selection	6338706
104859579	104859602	6	-	27260156	EWS502	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.6050505709588379	[42]	[53,56,108,58]	9	hSpCas9	negative selection	6338707
104859591	104859614	6	+	27260156	EW8	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.0816200074507103	[9]	[2,3,19,0]	-1	hSpCas9	negative selection	6395695
104852320	104852343	6	+	27260156	EW8	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.2591462339821169	[1792]	[1291,1310,941,1362]	-5	hSpCas9	negative selection	6395696
104859562	104859585	6	+	27260156	EW8	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.5300427974819973	[265]	[364,313,270,306]	8	hSpCas9	negative selection	6395697
104781987	104782010	6	+	27260156	EW8	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.1473770751223167	[458]	[228,153,173,119]	-9	hSpCas9	negative selection	6436709
104850943	104850966	6	-	27260156	EW8	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.09386506905548786	[865]	[730,820,792,639]	1	hSpCas9	negative selection	6459956
104852336	104852359	6	-	27260156	EW8	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.29994844326220615	[108]	[157,82,102,96]	5	hSpCas9	negative selection	6459957
104859579	104859602	6	-	27260156	EW8	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.16824436486112626	[42]	[72,34,16,38]	3	hSpCas9	negative selection	6459958
104859591	104859614	6	+	27260156	CORL105	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.42738562802253366	[9]	[1,38,8,10]	7	hSpCas9	negative selection	6516946
104852320	104852343	6	+	27260156	CORL105	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.12830797245642	[1792]	[2453,1842,2966,2032]	2	hSpCas9	negative selection	6516947
104859562	104859585	6	+	27260156	CORL105	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.8673243637710164	[265]	[549,581,672,482]	9	hSpCas9	negative selection	6516948
104781987	104782010	6	+	27260156	CORL105	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.0983981685833193	[458]	[232,295,279,197]	-9	hSpCas9	negative selection	6557960
104850943	104850966	6	-	27260156	CORL105	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.07763760563689093	[865]	[961,1251,1087,972]	1	hSpCas9	negative selection	6581207
104852336	104852359	6	-	27260156	CORL105	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	-0.013828147014463443	[108]	[56,121,251,91]	0	hSpCas9	negative selection	6581208
104859579	104859602	6	-	27260156	CORL105	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.14323615055760364	[42]	[38,81,29,27]	-3	hSpCas9	negative selection	6581209
104859591	104859614	6	+	27260156	HS294T	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-1.3606509120439823	[9]	[0,0,2,0]	-9	hSpCas9	negative selection	6638197
104852320	104852343	6	+	27260156	HS294T	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.1071815589387024	[1792]	[487,679,705,725]	-1	hSpCas9	negative selection	6638198
104859562	104859585	6	+	27260156	HS294T	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	1.2500007524957746	[265]	[116,490,201,156]	9	hSpCas9	negative selection	6638199
104781987	104782010	6	+	27260156	HS294T	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.36123656809742377	[458]	[61,72,132,324]	-5	hSpCas9	negative selection	6679211
104850943	104850966	6	-	27260156	HS294T	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.07956298054721611	[865]	[289,344,339,463]	1	hSpCas9	negative selection	6702458
104852336	104852359	6	-	27260156	HS294T	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.3867967992711441	[108]	[35,37,106,38]	5	hSpCas9	negative selection	6702459
104859579	104859602	6	-	27260156	HS294T	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.7007625696353075	[42]	[6,9,9,14]	-7	hSpCas9	negative selection	6702460
104859591	104859614	6	+	27260156	HCC44	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.4492742512558534	[9]	[0,24,15,16]	7	hSpCas9	negative selection	6759448
104852320	104852343	6	+	27260156	HCC44	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.08250594307770709	[1792]	[2013,2047,2512,2063]	1	hSpCas9	negative selection	6759449
104859562	104859585	6	+	27260156	HCC44	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.4801647614095934	[265]	[472,409,370,418]	7	hSpCas9	negative selection	6759450
104781987	104782010	6	+	27260156	HCC44	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.7602330859569515	[458]	[255,171,61,113]	-9	hSpCas9	negative selection	6800462
104850943	104850966	6	-	27260156	HCC44	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.1700358666506553	[865]	[1250,830,1504,938]	2	hSpCas9	negative selection	6823709
104852336	104852359	6	-	27260156	HCC44	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.8862136365442848	[108]	[406,122,175,225]	9	hSpCas9	negative selection	6823710
104859579	104859602	6	-	27260156	HCC44	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.5231580550728037	[42]	[39,9,16,67]	-7	hSpCas9	negative selection	6823711
104859591	104859614	6	+	27260156	G402	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.7009705606109478	[9]	[0,0,25,0]	-7	hSpCas9	negative selection	6880699
104852320	104852343	6	+	27260156	G402	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.07189019998656021	[1792]	[2587,2668,1995,1214]	-1	hSpCas9	negative selection	6880700
104859562	104859585	6	+	27260156	G402	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.18610341957001197	[265]	[398,507,402,186]	2	hSpCas9	negative selection	6880701
104781987	104782010	6	+	27260156	G402	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-2.0199968344115833	[458]	[114,134,195,103]	-9	hSpCas9	negative selection	6921713
104850943	104850966	6	-	27260156	G402	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.3294930057936235	[865]	[1148,1437,1166,1522]	4	hSpCas9	negative selection	6944960
104852336	104852359	6	-	27260156	G402	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.6350693024823084	[108]	[272,121,162,268]	7	hSpCas9	negative selection	6944961
104859579	104859602	6	-	27260156	G402	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.20336045630406652	[42]	[19,6,99,48]	-3	hSpCas9	negative selection	6944962
104859591	104859614	6	+	27260156	L33	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-1.8572755378823667	[9]	[1,0,0,4]	-9	hSpCas9	negative selection	7001950
104852320	104852343	6	+	27260156	L33	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.1986188231517667	[1792]	[1600,598,975,1631]	-4	hSpCas9	negative selection	7001951
104859562	104859585	6	+	27260156	L33	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.30179695552975794	[265]	[378,117,229,277]	6	hSpCas9	negative selection	7001952
104781987	104782010	6	+	27260156	L33	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.06837166236315784	[458]	[473,229,270,284]	-1	hSpCas9	negative selection	7042964
104850943	104850966	6	-	27260156	L33	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	-0.2542545957167749	[865]	[658,325,444,742]	-5	hSpCas9	negative selection	7066211
104852336	104852359	6	-	27260156	L33	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.8111659663587847	[108]	[169,64,162,177]	9	hSpCas9	negative selection	7066212
104859579	104859602	6	-	27260156	L33	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.23264972089615865	[42]	[26,9,28,48]	-5	hSpCas9	negative selection	7066213
104859591	104859614	6	+	27260156	K562	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.839683797995999	[9]	[24,18,0,18]	9	hSpCas9	negative selection	7123201
104852320	104852343	6	+	27260156	K562	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.1973999901408785	[1792]	[1425,1114,1353,1611]	-2	hSpCas9	negative selection	7123202
104859562	104859585	6	+	27260156	K562	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.357919725990208	[265]	[225,450,321,220]	4	hSpCas9	negative selection	7123203
104781987	104782010	6	+	27260156	K562	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.9277999148779096	[458]	[149,397,201,120]	-8	hSpCas9	negative selection	7164215
104850943	104850966	6	-	27260156	K562	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.3602114652242351	[865]	[933,945,1056,996]	4	hSpCas9	negative selection	7187462
104852336	104852359	6	-	27260156	K562	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.37265023754973226	[108]	[52,190,213,48]	5	hSpCas9	negative selection	7187463
104859579	104859602	6	-	27260156	K562	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.5214150763180858	[42]	[145,22,22,34]	6	hSpCas9	negative selection	7187464
104859591	104859614	6	+	27260156	HT29	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.376590036951038	[9]	[24,11,24,2]	7	hSpCas9	negative selection	7244452
104852320	104852343	6	+	27260156	HT29	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.08221641752585751	[1792]	[2374,2359,2686,1856]	1	hSpCas9	negative selection	7244453
104859562	104859585	6	+	27260156	HT29	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.5744352463318089	[265]	[528,523,459,423]	9	hSpCas9	negative selection	7244454
104781987	104782010	6	+	27260156	HT29	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.112129676834647	[458]	[367,313,176,192]	-9	hSpCas9	negative selection	7285466
104850943	104850966	6	-	27260156	HT29	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.10240635554753419	[865]	[1342,1361,985,887]	2	hSpCas9	negative selection	7308713
104852336	104852359	6	-	27260156	HT29	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.24779116083074548	[108]	[73,116,311,119]	5	hSpCas9	negative selection	7308714
104859579	104859602	6	-	27260156	HT29	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.2900608717831896	[42]	[18,32,72,42]	-5	hSpCas9	negative selection	7308715
104859591	104859614	6	+	27260156	MHHES1	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-1.9128870381050813	[9]	[9,0,0,0]	-9	hSpCas9	negative selection	7365703
104852320	104852343	6	+	27260156	MHHES1	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.07490863688794058	[1792]	[1968,1935,2509,1354]	-1	hSpCas9	negative selection	7365704
104859562	104859585	6	+	27260156	MHHES1	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.5938832472898008	[265]	[566,582,394,312]	8	hSpCas9	negative selection	7365705
104781987	104782010	6	+	27260156	MHHES1	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.049687942312254	[458]	[438,309,99,186]	-9	hSpCas9	negative selection	7406717
104850943	104850966	6	-	27260156	MHHES1	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.15499675549956227	[865]	[1085,1452,1095,790]	3	hSpCas9	negative selection	7429964
104852336	104852359	6	-	27260156	MHHES1	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	-0.035878010468013866	[108]	[205,99,107,79]	0	hSpCas9	negative selection	7429965
104859579	104859602	6	-	27260156	MHHES1	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.354534376257849	[42]	[68,82,44,53]	6	hSpCas9	negative selection	7429966
104859591	104859614	6	+	27260156	MEWO	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.618780467481808	[9]	[18,12,11]	9	hSpCas9	negative selection	7486954
104852320	104852343	6	+	27260156	MEWO	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.02969709884982885	[1792]	[1838,1521,1606]	0	hSpCas9	negative selection	7486955
104859562	104859585	6	+	27260156	MEWO	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.2792295966058055	[265]	[388,259,273]	6	hSpCas9	negative selection	7486956
104781987	104782010	6	+	27260156	MEWO	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.13517119843858322	[458]	[328,379,451]	-3	hSpCas9	negative selection	7527968
104850943	104850966	6	-	27260156	MEWO	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	-0.11781435812990426	[865]	[770,856,615]	-3	hSpCas9	negative selection	7551215
104852336	104852359	6	-	27260156	MEWO	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.2843840311335071	[108]	[166,93,119]	6	hSpCas9	negative selection	7551216
104859579	104859602	6	-	27260156	MEWO	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.8702824308934409	[42]	[21,24,18]	-9	hSpCas9	negative selection	7551217
104859591	104859614	6	+	27260156	LNCAPCLONEFGC	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.8120350158661953	[9]	[9,3,0,4]	-8	hSpCas9	negative selection	7608205
104852320	104852343	6	+	27260156	LNCAPCLONEFGC	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.09695868826931453	[1792]	[1647,1302,1597,1547]	-1	hSpCas9	negative selection	7608206
104859562	104859585	6	+	27260156	LNCAPCLONEFGC	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.20159150842870943	[265]	[251,362,229,250]	3	hSpCas9	negative selection	7608207
104781987	104782010	6	+	27260156	LNCAPCLONEFGC	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.887361680526386	[458]	[128,101,99,116]	-9	hSpCas9	negative selection	7649219
104850943	104850966	6	-	27260156	LNCAPCLONEFGC	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	-0.06816556605554003	[865]	[667,711,919,721]	-1	hSpCas9	negative selection	7672466
104852336	104852359	6	-	27260156	LNCAPCLONEFGC	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.3750023743620219	[108]	[170,52,112,176]	6	hSpCas9	negative selection	7672467
104859579	104859602	6	-	27260156	LNCAPCLONEFGC	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.27148473473866686	[42]	[15,18,70,29]	-4	hSpCas9	negative selection	7672468
104859591	104859614	6	+	27260156	PANC0327	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-2.832122414051458	[9]	[0,0,0,1]	-9	hSpCas9	negative selection	7729456
104852320	104852343	6	+	27260156	PANC0327	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.23149518987253948	[1792]	[2043,1309,2083,2127]	3	hSpCas9	negative selection	7729457
104859562	104859585	6	+	27260156	PANC0327	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.37716184583342965	[265]	[257,257,432,280]	5	hSpCas9	negative selection	7729458
104781987	104782010	6	+	27260156	PANC0327	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.873059176706857	[458]	[119,125,96,100]	-9	hSpCas9	negative selection	7770470
104850943	104850966	6	-	27260156	PANC0327	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.48573912730954605	[865]	[898,941,1001,1467]	7	hSpCas9	negative selection	7793717
104852336	104852359	6	-	27260156	PANC0327	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.4705905027404873	[108]	[145,168,73,143]	7	hSpCas9	negative selection	7793718
104859579	104859602	6	-	27260156	PANC0327	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.10644370432093098	[42]	[50,19,39,56]	1	hSpCas9	negative selection	7793719
104859591	104859614	6	+	27260156	NCIH2009	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-1.970662838596926	[9]	[4,1,3]	-9	hSpCas9	negative selection	7850707
104852320	104852343	6	+	27260156	NCIH2009	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.2609703967346466	[1792]	[3586,2893,2636]	3	hSpCas9	negative selection	7850708
104859562	104859585	6	+	27260156	NCIH2009	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	1.2040339591325668	[265]	[920,688,972]	9	hSpCas9	negative selection	7850709
104781987	104782010	6	+	27260156	NCIH2009	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.7967732037111988	[458]	[300,152,122]	-9	hSpCas9	negative selection	7891721
104850943	104850966	6	-	27260156	NCIH2009	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.12264860547612544	[865]	[1652,1372,988]	1	hSpCas9	negative selection	7914968
104852336	104852359	6	-	27260156	NCIH2009	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	-0.18465376338516482	[108]	[114,133,148]	-3	hSpCas9	negative selection	7914969
104859579	104859602	6	-	27260156	NCIH2009	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.8990063924217706	[42]	[130,92,115]	9	hSpCas9	negative selection	7914970
104859591	104859614	6	+	27260156	NCIH1373	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.15394932519716154	[9]	[50,0,0,0]	1	hSpCas9	negative selection	7971958
104852320	104852343	6	+	27260156	NCIH1373	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.6162052851587256	[1792]	[878,1462,1070,465]	-6	hSpCas9	negative selection	7971959
104859562	104859585	6	+	27260156	NCIH1373	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.7232588634343338	[265]	[420,768,409,82]	7	hSpCas9	negative selection	7971960
104781987	104782010	6	+	27260156	NCIH1373	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-2.204246025893512	[458]	[173,45,75,44]	-9	hSpCas9	negative selection	8012972
104850943	104850966	6	-	27260156	NCIH1373	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.2815127732484942	[865]	[1728,665,1228,323]	2	hSpCas9	negative selection	8036219
104852336	104852359	6	-	27260156	NCIH1373	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	-0.12222754299986027	[108]	[81,107,128,32]	-1	hSpCas9	negative selection	8036220
104859579	104859602	6	-	27260156	NCIH1373	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	1.1987285659572744	[42]	[226,49,142,10]	9	hSpCas9	negative selection	8036221
104859591	104859614	6	+	27260156	PATU8902	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-3.7970053107489825	[9]	[0,0,0,0]	-9	hSpCas9	negative selection	8093209
104852320	104852343	6	+	27260156	PATU8902	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.32680499347527747	[1792]	[3636,2071,3027,3870]	3	hSpCas9	negative selection	8093210
104859562	104859585	6	+	27260156	PATU8902	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.7167932722252309	[265]	[607,579,670,547]	7	hSpCas9	negative selection	8093211
104781987	104782010	6	+	27260156	PATU8902	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.9146437527620501	[458]	[105,310,135,128]	-9	hSpCas9	negative selection	8134223
104850943	104850966	6	-	27260156	PATU8902	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.6422823090362851	[865]	[1704,1671,1098,3428]	6	hSpCas9	negative selection	8157470
104852336	104852359	6	-	27260156	PATU8902	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.2150392740533844	[108]	[126,268,125,197]	2	hSpCas9	negative selection	8157471
104859579	104859602	6	-	27260156	PATU8902	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.329182207273929	[42]	[68,134,3,115]	3	hSpCas9	negative selection	8157472
104859591	104859614	6	+	27260156	PANC1	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.020353208948554524	[9]	[0,6,25,0]	0	hSpCas9	negative selection	8214460
104852320	104852343	6	+	27260156	PANC1	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.3669291132520536	[1792]	[2251,2505,2090,1281]	6	hSpCas9	negative selection	8214461
104859562	104859585	6	+	27260156	PANC1	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.5256654961212004	[265]	[291,447,352,254]	8	hSpCas9	negative selection	8214462
104781987	104782010	6	+	27260156	PANC1	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.8755511023935174	[458]	[118,68,157,78]	-9	hSpCas9	negative selection	8255474
104850943	104850966	6	-	27260156	PANC1	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.34258945759919046	[865]	[806,979,970,999]	5	hSpCas9	negative selection	8278721
104852336	104852359	6	-	27260156	PANC1	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.8543720379778648	[108]	[152,175,289,73]	9	hSpCas9	negative selection	8278722
104859579	104859602	6	-	27260156	PANC1	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.3269482698461621	[42]	[28,25,47,15]	-5	hSpCas9	negative selection	8278723
104859591	104859614	6	+	27260156	PANC0813	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.45122107513008647	[9]	[12,7,9,31]	7	hSpCas9	negative selection	8335711
104852320	104852343	6	+	27260156	PANC0813	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.08602241249455811	[1792]	[2653,1871,2331,2125]	1	hSpCas9	negative selection	8335712
104859562	104859585	6	+	27260156	PANC0813	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.6960807605661685	[265]	[514,519,488,500]	9	hSpCas9	negative selection	8335713
104781987	104782010	6	+	27260156	PANC0813	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.5068554175782505	[458]	[196,197,188,175]	-9	hSpCas9	negative selection	8376725
104850943	104850966	6	-	27260156	PANC0813	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	-0.023072022688346516	[865]	[1118,1020,1094,790]	0	hSpCas9	negative selection	8399972
104852336	104852359	6	-	27260156	PANC0813	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.3693240323468152	[108]	[139,219,171,128]	6	hSpCas9	negative selection	8399973
104859579	104859602	6	-	27260156	PANC0813	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.1971899291711905	[42]	[31,83,16,41]	-3	hSpCas9	negative selection	8399974
104859591	104859614	6	+	27260156	RDES	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.40503233862387766	[9]	[7,7,7,10]	-6	hSpCas9	negative selection	8456962
104852320	104852343	6	+	27260156	RDES	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.25637483020893215	[1792]	[1403,1687,1824,2063]	-4	hSpCas9	negative selection	8456963
104859562	104859585	6	+	27260156	RDES	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.18186229897300255	[265]	[251,347,290,533]	3	hSpCas9	negative selection	8456964
104781987	104782010	6	+	27260156	RDES	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.579313476533209	[458]	[157,132,184,243]	-9	hSpCas9	negative selection	8497976
104850943	104850966	6	-	27260156	RDES	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.2906361275408452	[865]	[869,1194,1390,1510]	5	hSpCas9	negative selection	8521223
104852336	104852359	6	-	27260156	RDES	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.7728438605658148	[108]	[147,199,285,238]	9	hSpCas9	negative selection	8521224
104859579	104859602	6	-	27260156	RDES	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.1746810692822156	[42]	[36,58,38,95]	3	hSpCas9	negative selection	8521225
104859591	104859614	6	+	27260156	PC3	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	0.1451207656568707	[9]	[19,0,0,11]	3	hSpCas9	negative selection	8578213
104852320	104852343	6	+	27260156	PC3	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.2898294385136093	[1792]	[836,1184,2864,1677]	-6	hSpCas9	negative selection	8578214
104859562	104859585	6	+	27260156	PC3	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.42998392395786766	[265]	[192,380,707,321]	8	hSpCas9	negative selection	8578215
104781987	104782010	6	+	27260156	PC3	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.2438184611903217	[458]	[158,614,525,356]	-5	hSpCas9	negative selection	8619227
104850943	104850966	6	-	27260156	PC3	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.04185660039568928	[865]	[500,831,1634,975]	0	hSpCas9	negative selection	8642474
104852336	104852359	6	-	27260156	PC3	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.504035081111037	[108]	[78,86,325,218]	8	hSpCas9	negative selection	8642475
104859579	104859602	6	-	27260156	PC3	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	1.0428210044402237	[42]	[13,145,134,102]	9	hSpCas9	negative selection	8642476
104859591	104859614	6	+	27260156	PATU8988T	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.5561028736873519	[9]	[2,1,1,19]	-7	hSpCas9	negative selection	8699464
104852320	104852343	6	+	27260156	PATU8988T	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	0.17915063413232635	[1792]	[2377,1727,1917,1786]	3	hSpCas9	negative selection	8699465
104859562	104859585	6	+	27260156	PATU8988T	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.3830280243731554	[265]	[216,332,334,465]	6	hSpCas9	negative selection	8699466
104781987	104782010	6	+	27260156	PATU8988T	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.2756450592891975	[458]	[167,130,283,139]	-9	hSpCas9	negative selection	8740478
104850943	104850966	6	-	27260156	PATU8988T	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.35024860061911245	[865]	[1229,1023,997,1006]	6	hSpCas9	negative selection	8763725
104852336	104852359	6	-	27260156	PATU8988T	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.5784889841349818	[108]	[125,63,112,331]	8	hSpCas9	negative selection	8763726
104859579	104859602	6	-	27260156	PATU8988T	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.2896810241051888	[42]	[34,37,102,22]	5	hSpCas9	negative selection	8763727
104859591	104859614	6	+	27260156	T47D	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-1.1008280927494365	[9]	[0,3,5,10]	-9	hSpCas9	negative selection	8820715
104852320	104852343	6	+	27260156	T47D	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.04918783902471713	[1792]	[2059,1844,1971,2219]	-1	hSpCas9	negative selection	8820716
104859562	104859585	6	+	27260156	T47D	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.33090358513660967	[265]	[318,418,417,399]	7	hSpCas9	negative selection	8820717
104781987	104782010	6	+	27260156	T47D	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.953671095452368	[458]	[229,303,278,288]	-9	hSpCas9	negative selection	8861729
104850943	104850966	6	-	27260156	T47D	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.1926020438587902	[865]	[1149,1111,1103,1252]	4	hSpCas9	negative selection	8884976
104852336	104852359	6	-	27260156	T47D	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.44266276312375363	[108]	[207,134,149,201]	8	hSpCas9	negative selection	8884977
104859579	104859602	6	-	27260156	T47D	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.2836998415460026	[42]	[47,37,62,97]	6	hSpCas9	negative selection	8884978
104859591	104859614	6	+	27260156	SU8686	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-2.80800230849945	[9]	[0,0,0,2]	-9	hSpCas9	negative selection	8941966
104852320	104852343	6	+	27260156	SU8686	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.13431049229973646	[1792]	[1434,1253,1892,2026]	-2	hSpCas9	negative selection	8941967
104859562	104859585	6	+	27260156	SU8686	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.3148348910870522	[265]	[293,385,272,355]	5	hSpCas9	negative selection	8941968
104781987	104782010	6	+	27260156	SU8686	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-1.8349414634680494	[458]	[116,159,103,123]	-9	hSpCas9	negative selection	8982980
104850943	104850966	6	-	27260156	SU8686	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.0946211903943267	[865]	[772,849,1039,1046]	1	hSpCas9	negative selection	9006227
104852336	104852359	6	-	27260156	SU8686	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.6742977377776662	[108]	[159,154,131,257]	9	hSpCas9	negative selection	9006228
104859579	104859602	6	-	27260156	SU8686	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.020664150500778966	[42]	[62,32,22,47]	0	hSpCas9	negative selection	9006229
104859591	104859614	6	+	27260156	SKES1	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.6553003446940933	[9]	[8,0,8,5]	-8	hSpCas9	negative selection	9063217
104852320	104852343	6	+	27260156	SKES1	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.022157871456670364	[1792]	[1675,2068,1781,1549]	0	hSpCas9	negative selection	9063218
104859562	104859585	6	+	27260156	SKES1	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.09723942554840637	[265]	[345,239,245,301]	2	hSpCas9	negative selection	9063219
104781987	104782010	6	+	27260156	SKES1	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.6370216125383655	[458]	[247,307,324,288]	-8	hSpCas9	negative selection	9104231
104850943	104850966	6	-	27260156	SKES1	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.1580974198646149	[865]	[1221,889,1042,742]	3	hSpCas9	negative selection	9127478
104852336	104852359	6	-	27260156	SKES1	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	-0.2877438662369123	[108]	[84,62,131,72]	-6	hSpCas9	negative selection	9127479
104859579	104859602	6	-	27260156	SKES1	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	-0.5314814816842115	[42]	[34,37,24,22]	-8	hSpCas9	negative selection	9127480
104859591	104859614	6	+	27260156	TOV112D	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-2.830147137110462	[9]	[0,2,0,0]	-9	hSpCas9	negative selection	9184468
104852320	104852343	6	+	27260156	TOV112D	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.0031202825926768263	[1792]	[1677,2010,1910,1613]	0	hSpCas9	negative selection	9184469
104859562	104859585	6	+	27260156	TOV112D	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.28006683300802737	[265]	[375,555,241,184]	5	hSpCas9	negative selection	9184470
104781987	104782010	6	+	27260156	TOV112D	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.6391838302938354	[458]	[231,342,256,352]	-8	hSpCas9	negative selection	9225482
104850943	104850966	6	-	27260156	TOV112D	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.01562867853085015	[865]	[1032,1127,626,794]	0	hSpCas9	negative selection	9248729
104852336	104852359	6	-	27260156	TOV112D	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.5039104034199708	[108]	[214,213,68,140]	8	hSpCas9	negative selection	9248730
104859579	104859602	6	-	27260156	TOV112D	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.2477617905431222	[42]	[59,89,21,42]	5	hSpCas9	negative selection	9248731
104859591	104859614	6	+	27260156	TC71	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-0.34532151186934446	[9]	[10,10,1,9]	-7	hSpCas9	negative selection	9305719
104852320	104852343	6	+	27260156	TC71	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.0006599880953388482	[1792]	[2034,1882,1886,1874]	0	hSpCas9	negative selection	9305720
104859562	104859585	6	+	27260156	TC71	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.17537381990416023	[265]	[333,332,223,404]	4	hSpCas9	negative selection	9305721
104781987	104782010	6	+	27260156	TC71	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.30689628713134415	[458]	[452,335,397,402]	-7	hSpCas9	negative selection	9346733
104850943	104850966	6	-	27260156	TC71	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.034826544358135036	[865]	[908,1150,895,843]	0	hSpCas9	negative selection	9369980
104852336	104852359	6	-	27260156	TC71	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.49936721416499896	[108]	[176,137,148,198]	9	hSpCas9	negative selection	9369981
104859579	104859602	6	-	27260156	TC71	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.9483033462752011	[42]	[70,98,85,100]	9	hSpCas9	negative selection	9369982
104859591	104859614	6	+	27260156	TC32	viability	CGCGGCGCAGCGAGCGCGTCAGG	HACE1	ENSG00000085382	-1.4965114548480258	[9]	[2,0,8,1]	-9	hSpCas9	negative selection	9426970
104852320	104852343	6	+	27260156	TC32	viability	TGTTGATCAGCCATAACCATTGG	HACE1	ENSG00000085382	-0.22535964180557455	[1792]	[1526,1057,1708,1570]	-4	hSpCas9	negative selection	9426971
104859562	104859585	6	+	27260156	TC32	viability	CTCACCCTCGGGCAACTCCACGG	HACE1	ENSG00000085382	0.08424387223280538	[265]	[231,136,356,395]	1	hSpCas9	negative selection	9426972
104781987	104782010	6	+	27260156	TC32	viability	ACAGTATTAGGTTGGTGCAAAAG	HACE1	ENSG00000085382	-0.996131210845581	[458]	[267,123,313,189]	-9	hSpCas9	negative selection	9467984
104850943	104850966	6	-	27260156	TC32	viability	TTTGATGTCAATTATGCATTCGG	HACE1	ENSG00000085382	0.07322507753025242	[865]	[782,688,1194,835]	1	hSpCas9	negative selection	9491231
104852336	104852359	6	-	27260156	TC32	viability	TGTTTATACATTAATGCCAATGG	HACE1	ENSG00000085382	0.5586433162882567	[108]	[155,120,220,116]	8	hSpCas9	negative selection	9491232
104859579	104859602	6	-	27260156	TC32	viability	GCTGCGCCGCGCGCGCACCGTGG	HACE1	ENSG00000085382	0.26708784170649835	[42]	[62,25,47,61]	5	hSpCas9	negative selection	9491233
104771974	104771997	6	-	27869803	HPAFII	viability after 27 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.853802528236156	[123]	[239,15,NaN]	7	hSpCas9	negative selection	9593004
104777200	104777223	6	+	27869803	HPAFII	viability after 27 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.9763179263542816	[126]	[252,29,NaN]	7	hSpCas9	negative selection	9593005
104785161	104785184	6	+	27869803	HPAFII	viability after 27 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.0019572485094593306	[487]	[215,290,NaN]	0	hSpCas9	negative selection	9593006
104852316	104852339	6	-	27869803	HPAFII	viability after 27 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.5672978832543418	[310]	[136,329,NaN]	4	hSpCas9	negative selection	9593009
104859566	104859589	6	-	27869803	HPAFII	viability after 27 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.31844752615240035	[344]	[145,144,NaN]	-2	hSpCas9	negative selection	9593010
104771974	104771997	6	-	27869803	HPAFII	viability after 15 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	0.5320262942303267	[123]	[344,97,NaN]	6	hSpCas9	negative selection	9675453
104777200	104777223	6	+	27869803	HPAFII	viability after 15 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.7482245755755708	[126]	[404,119,NaN]	8	hSpCas9	negative selection	9675454
104785161	104785184	6	+	27869803	HPAFII	viability after 15 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	-0.3843195058672706	[487]	[571,295,NaN]	-4	hSpCas9	negative selection	9675455
104852316	104852339	6	-	27869803	HPAFII	viability after 15 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.14820624494789203	[310]	[399,351,NaN]	1	hSpCas9	negative selection	9675458
104859566	104859589	6	-	27869803	HPAFII	viability after 15 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	0.41526585048862086	[344]	[536,467,NaN]	5	hSpCas9	negative selection	9675459
104771974	104771997	6	-	27869803	ASPC1	viability after 36 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.9770608430779247	[432]	[11,99,102]	-7	hSpCas9	negative selection	9757902
104777200	104777223	6	+	27869803	ASPC1	viability after 36 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	0.04548592796363571	[350]	[69,47,226]	0	hSpCas9	negative selection	9757903
104785161	104785184	6	+	27869803	ASPC1	viability after 36 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.21147088794806246	[790]	[444,284,255]	2	hSpCas9	negative selection	9757904
104852316	104852339	6	-	27869803	ASPC1	viability after 36 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.2796318292132407	[764]	[589,132,285]	3	hSpCas9	negative selection	9757907
104859566	104859589	6	-	27869803	ASPC1	viability after 36 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	1.0867218973294759	[960]	[1168,725,373]	8	hSpCas9	negative selection	9757908
104771974	104771997	6	-	27869803	PATU8988S	viability after 35 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.555446668536947	[353]	[102,90,NaN]	-5	hSpCas9	negative selection	9840351
104777200	104777223	6	+	27869803	PATU8988S	viability after 35 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.60559429962241	[257]	[411,219,NaN]	9	hSpCas9	negative selection	9840352
104785161	104785184	6	+	27869803	PATU8988S	viability after 35 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.40618239136893475	[854]	[379,532,NaN]	4	hSpCas9	negative selection	9840353
104852316	104852339	6	-	27869803	PATU8988S	viability after 35 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.5278361623766579	[538]	[304,320,NaN]	6	hSpCas9	negative selection	9840356
104859566	104859589	6	-	27869803	PATU8988S	viability after 35 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.41718221868432326	[1032]	[121,501,NaN]	-4	hSpCas9	negative selection	9840357
104771974	104771997	6	-	27869803	PATU8988S	viability after 31 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	-0.2692366123519122	[353]	[139,87,NaN]	-3	hSpCas9	negative selection	9922800
104777200	104777223	6	+	27869803	PATU8988S	viability after 31 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.393327190313629	[257]	[260,281,NaN]	9	hSpCas9	negative selection	9922801
104785161	104785184	6	+	27869803	PATU8988S	viability after 31 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.5268186994757637	[854]	[433,563,NaN]	6	hSpCas9	negative selection	9922802
104852316	104852339	6	-	27869803	PATU8988S	viability after 31 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.5797026984293042	[538]	[179,500,NaN]	7	hSpCas9	negative selection	9922805
104859566	104859589	6	-	27869803	PATU8988S	viability after 31 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.05942189312338553	[1032]	[206,634,NaN]	0	hSpCas9	negative selection	9922806
104771974	104771997	6	-	27869803	HPAFII	viability after 35 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	1.2505010316111964	[123]	[273,8,NaN]	8	hSpCas9	negative selection	10005249
104777200	104777223	6	+	27869803	HPAFII	viability after 35 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.6762735754814204	[126]	[347,44,NaN]	9	hSpCas9	negative selection	10005250
104785161	104785184	6	+	27869803	HPAFII	viability after 35 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	0.044586110570552395	[487]	[211,302,NaN]	0	hSpCas9	negative selection	10005251
104852316	104852339	6	-	27869803	HPAFII	viability after 35 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.20883041106669437	[310]	[109,262,NaN]	1	hSpCas9	negative selection	10005254
104859566	104859589	6	-	27869803	HPAFII	viability after 35 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.58205021929311	[344]	[47,193,NaN]	-3	hSpCas9	negative selection	10005255
104771974	104771997	6	-	27869803	HPAFII	viability after 31 days	TGGGATTAGCGTTGAACCACAGG	HACE1	ENSG00000085382	1.0996568675559653	[123]	[274,11,NaN]	7	hSpCas9	negative selection	10087698
104777200	104777223	6	+	27869803	HPAFII	viability after 31 days	GCATACCTCTGTGAACCAGCAGG	HACE1	ENSG00000085382	1.4678886818423127	[126]	[356,22,NaN]	9	hSpCas9	negative selection	10087699
104785161	104785184	6	+	27869803	HPAFII	viability after 31 days	TGGAGGTTCAAATGGAGGAATGG	HACE1	ENSG00000085382	-0.04161889165131505	[487]	[200,336,NaN]	0	hSpCas9	negative selection	10087700
104852316	104852339	6	-	27869803	HPAFII	viability after 31 days	TGGTTATGGCTGATCAACACAGG	HACE1	ENSG00000085382	0.7097668813842892	[310]	[172,407,NaN]	5	hSpCas9	negative selection	10087703
104859566	104859589	6	-	27869803	HPAFII	viability after 31 days	CGCACCGTGGAGTTGCCCGAGGG	HACE1	ENSG00000085382	-0.018573873406416697	[344]	[104,284,NaN]	0	hSpCas9	negative selection	10087704
104859627	104859650	6	-	28162770	P31FUJ	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-4.232802204414378	[47]	[2]	-9	hSpCas9	negative selection	10167264
104785156	104785179	6	+	28162770	P31FUJ	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.15215963095902718	[205]	[268]	1	hSpCas9	negative selection	10167265
104859567	104859590	6	-	28162770	P31FUJ	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.27002576074228013	[258]	[366]	3	hSpCas9	negative selection	10167266
104811368	104811391	6	-	28162770	P31FUJ	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.7831393394546431	[584]	[1182]	8	hSpCas9	negative selection	10167267
104785297	104785320	6	+	28162770	P31FUJ	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.47295131362318144	[270]	[441]	5	hSpCas9	negative selection	10167268
104777205	104777228	6	-	28162770	P31FUJ	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.6352154995498499	[325]	[594]	7	hSpCas9	negative selection	10167269
104730375	104730398	6	-	28162770	P31FUJ	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.32296031985820306	[182]	[268]	3	hSpCas9	negative selection	10167270
104796648	104796671	6	+	28162770	P31FUJ	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.5825014707587164	[361]	[636]	6	hSpCas9	negative selection	10167271
104859627	104859650	6	-	28162770	TF1	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10336630
104785156	104785179	6	+	28162770	TF1	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	NaN	[NaN]	[274]	1	hSpCas9	negative selection	10336631
104859567	104859590	6	-	28162770	TF1	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10336632
104811368	104811391	6	-	28162770	TF1	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	NaN	[NaN]	[547]	1	hSpCas9	negative selection	10336633
104785297	104785320	6	+	28162770	TF1	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10336634
104777205	104777228	6	-	28162770	TF1	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10336635
104730375	104730398	6	-	28162770	TF1	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10336636
104796648	104796671	6	+	28162770	TF1	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	NaN	[NaN]	[427]	1	hSpCas9	negative selection	10336637
104859627	104859650	6	-	28162770	SKM1	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-4.281433316659303	[32]	[2]	-9	hSpCas9	negative selection	10505996
104785156	104785179	6	+	28162770	SKM1	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.8314405405819173	[47]	[150]	7	hSpCas9	negative selection	10505997
104859567	104859590	6	-	28162770	SKM1	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.5657284552611029	[59]	[156]	5	hSpCas9	negative selection	10505998
104811368	104811391	6	-	28162770	SKM1	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	1.1410319756240468	[167]	[654]	9	hSpCas9	negative selection	10505999
104785297	104785320	6	+	28162770	SKM1	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.7681785119701701	[91]	[276]	7	hSpCas9	negative selection	10506000
104777205	104777228	6	-	28162770	SKM1	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.7322640054762344	[94]	[278]	7	hSpCas9	negative selection	10506001
104730375	104730398	6	-	28162770	SKM1	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.8080486922276887	[41]	[129]	7	hSpCas9	negative selection	10506002
104796648	104796671	6	+	28162770	SKM1	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.43394328302546903	[84]	[202]	4	hSpCas9	negative selection	10506003
104859627	104859650	6	-	28162770	SKM1	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-4.281433316659303	[32]	[2]	-9	hSpCas9	negative selection	10675362
104785156	104785179	6	+	28162770	SKM1	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.8314405405819173	[47]	[150]	7	hSpCas9	negative selection	10675363
104859567	104859590	6	-	28162770	SKM1	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.5657284552611029	[59]	[156]	5	hSpCas9	negative selection	10675364
104811368	104811391	6	-	28162770	SKM1	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	1.1410319756240468	[167]	[654]	9	hSpCas9	negative selection	10675365
104785297	104785320	6	+	28162770	SKM1	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.7681785119701701	[91]	[276]	7	hSpCas9	negative selection	10675366
104777205	104777228	6	-	28162770	SKM1	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.7322640054762344	[94]	[278]	7	hSpCas9	negative selection	10675367
104730375	104730398	6	-	28162770	SKM1	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.8080486922276887	[41]	[129]	7	hSpCas9	negative selection	10675368
104796648	104796671	6	+	28162770	SKM1	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.43394328302546903	[84]	[202]	4	hSpCas9	negative selection	10675369
104859627	104859650	6	-	28162770	PL21	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-4.632750399675422	[56]	[0]	-9	hSpCas9	negative selection	10844728
104785156	104785179	6	+	28162770	PL21	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.8808610980159073	[135]	[108]	7	hSpCas9	negative selection	10844729
104859567	104859590	6	-	28162770	PL21	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.2266118258505112	[215]	[109]	2	hSpCas9	negative selection	10844730
104811368	104811391	6	-	28162770	PL21	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	1.4672095335582709	[594]	[715]	9	hSpCas9	negative selection	10844731
104785297	104785320	6	+	28162770	PL21	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.08839125683686477	[321]	[148]	0	hSpCas9	negative selection	10844732
104777205	104777228	6	-	28162770	PL21	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	-0.536825979676886	[379]	[113]	-4	hSpCas9	negative selection	10844733
104730375	104730398	6	-	28162770	PL21	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	1.2001396144893202	[120]	[120]	8	hSpCas9	negative selection	10844734
104796648	104796671	6	+	28162770	PL21	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	1.3869081260950469	[245]	[279]	9	hSpCas9	negative selection	10844735
104859627	104859650	6	-	28162770	P31FUJ	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-4.232802204414378	[47]	[2]	-9	hSpCas9	negative selection	11014094
104785156	104785179	6	+	28162770	P31FUJ	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.15215963095902718	[205]	[268]	1	hSpCas9	negative selection	11014095
104859567	104859590	6	-	28162770	P31FUJ	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.27002576074228013	[258]	[366]	3	hSpCas9	negative selection	11014096
104811368	104811391	6	-	28162770	P31FUJ	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.7831393394546431	[584]	[1182]	8	hSpCas9	negative selection	11014097
104785297	104785320	6	+	28162770	P31FUJ	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.47295131362318144	[270]	[441]	5	hSpCas9	negative selection	11014098
104777205	104777228	6	-	28162770	P31FUJ	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.6352154995498499	[325]	[594]	7	hSpCas9	negative selection	11014099
104730375	104730398	6	-	28162770	P31FUJ	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.32296031985820306	[182]	[268]	3	hSpCas9	negative selection	11014100
104796648	104796671	6	+	28162770	P31FUJ	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.5825014707587164	[361]	[636]	6	hSpCas9	negative selection	11014101
104859627	104859650	6	-	28162770	OCIAML5	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-5.552506289005089	[25]	[0]	-9	hSpCas9	negative selection	11183460
104785156	104785179	6	+	28162770	OCIAML5	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.8703994536070941	[119]	[395]	7	hSpCas9	negative selection	11183461
104859567	104859590	6	-	28162770	OCIAML5	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	-0.26710407014284077	[119]	[179]	-2	hSpCas9	negative selection	11183462
104811368	104811391	6	-	28162770	OCIAML5	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.8778785956244368	[308]	[1024]	7	hSpCas9	negative selection	11183463
104785297	104785320	6	+	28162770	OCIAML5	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	-0.42709995434142123	[180]	[242]	-3	hSpCas9	negative selection	11183464
104777205	104777228	6	-	28162770	OCIAML5	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.8519486015009223	[154]	[504]	7	hSpCas9	negative selection	11183465
104730375	104730398	6	-	28162770	OCIAML5	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.6180755278553012	[121]	[337]	5	hSpCas9	negative selection	11183466
104796648	104796671	6	+	28162770	OCIAML5	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.36440101651534573	[243]	[566]	3	hSpCas9	negative selection	11183467
104859627	104859650	6	-	28162770	EOL1	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-5.162915069679805	[135]	[1]	-9	hSpCas9	negative selection	11352826
104785156	104785179	6	+	28162770	EOL1	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	-0.0531994215823377	[192]	[97]	0	hSpCas9	negative selection	11352827
104859567	104859590	6	-	28162770	EOL1	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	-0.2955780427939684	[423]	[181]	-2	hSpCas9	negative selection	11352828
104811368	104811391	6	-	28162770	EOL1	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.2815000407919672	[1114]	[713]	2	hSpCas9	negative selection	11352829
104785297	104785320	6	+	28162770	EOL1	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	-0.10433334841659414	[554]	[271]	-1	hSpCas9	negative selection	11352830
104777205	104777228	6	-	28162770	EOL1	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	-0.4957182425101201	[644]	[240]	-4	hSpCas9	negative selection	11352831
104730375	104730398	6	-	28162770	EOL1	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	-0.7347969254731977	[198]	[62]	-5	hSpCas9	negative selection	11352832
104796648	104796671	6	+	28162770	EOL1	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.7610490392876552	[335]	[299]	6	hSpCas9	negative selection	11352833
104859627	104859650	6	-	28162770	MOLM13	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-6.132023460642549	[96]	[0]	-9	hSpCas9	negative selection	11522192
104785156	104785179	6	+	28162770	MOLM13	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.8049243688221495	[189]	[239]	6	hSpCas9	negative selection	11522193
104859567	104859590	6	-	28162770	MOLM13	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.05475141518121655	[252]	[189]	0	hSpCas9	negative selection	11522194
104811368	104811391	6	-	28162770	MOLM13	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.7014717374128148	[898]	[1056]	5	hSpCas9	negative selection	11522195
104785297	104785320	6	+	28162770	MOLM13	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.9445659466158085	[377]	[525]	7	hSpCas9	negative selection	11522196
104777205	104777228	6	-	28162770	MOLM13	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.16349594594972738	[551]	[446]	1	hSpCas9	negative selection	11522197
104730375	104730398	6	-	28162770	MOLM13	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	-0.06902594476946869	[250]	[172]	0	hSpCas9	negative selection	11522198
104796648	104796671	6	+	28162770	MOLM13	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.047671643160054844	[371]	[277]	0	hSpCas9	negative selection	11522199
104859627	104859650	6	-	28162770	HEL	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-2.584330076545564	[102]	[10]	-8	hSpCas9	negative selection	11691558
104785156	104785179	6	+	28162770	HEL	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	-0.7325524884857303	[178]	[68]	-5	hSpCas9	negative selection	11691559
104859567	104859590	6	-	28162770	HEL	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.17595775762751498	[245]	[177]	1	hSpCas9	negative selection	11691560
104811368	104811391	6	-	28162770	HEL	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.634929908789593	[740]	[736]	5	hSpCas9	negative selection	11691561
104785297	104785320	6	+	28162770	HEL	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.15347674769978625	[451]	[321]	1	hSpCas9	negative selection	11691562
104777205	104777228	6	-	28162770	HEL	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.39545677157218573	[418]	[352]	3	hSpCas9	negative selection	11691563
104730375	104730398	6	-	28162770	HEL	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	-0.6903874694918695	[193]	[76]	-4	hSpCas9	negative selection	11691564
104796648	104796671	6	+	28162770	HEL	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	-0.0730879951076988	[270]	[164]	0	hSpCas9	negative selection	11691565
104859627	104859650	6	-	28162770	MV411	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-1.6854482533586876	[83]	[21]	-8	hSpCas9	negative selection	11860924
104785156	104785179	6	+	28162770	MV411	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	-0.8999928128724507	[174]	[78]	-6	hSpCas9	negative selection	11860925
104859567	104859590	6	-	28162770	MV411	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.3794330965927655	[166]	[182]	3	hSpCas9	negative selection	11860926
104811368	104811391	6	-	28162770	MV411	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	-0.039293584523311775	[576]	[472]	0	hSpCas9	negative selection	11860927
104785297	104785320	6	+	28162770	MV411	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	-0.14758205491911114	[333]	[253]	-1	hSpCas9	negative selection	11860928
104777205	104777228	6	-	28162770	MV411	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	-0.08852837750486964	[283]	[224]	0	hSpCas9	negative selection	11860929
104730375	104730398	6	-	28162770	MV411	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	-0.2595224379371078	[134]	[94]	-2	hSpCas9	negative selection	11860930
104796648	104796671	6	+	28162770	MV411	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.27381296620707296	[270]	[275]	2	hSpCas9	negative selection	11860931
104859627	104859650	6	-	28162770	MONOMAC1	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-3.741357363283364	[34]	[2]	-9	hSpCas9	negative selection	12030290
104785156	104785179	6	+	28162770	MONOMAC1	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	-0.28818473511774884	[97]	[91]	-3	hSpCas9	negative selection	12030291
104859567	104859590	6	-	28162770	MONOMAC1	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.11108544830277833	[146]	[181]	1	hSpCas9	negative selection	12030292
104811368	104811391	6	-	28162770	MONOMAC1	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	1.2932249335721133	[382]	[1075]	9	hSpCas9	negative selection	12030293
104785297	104785320	6	+	28162770	MONOMAC1	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	1.5734813068176787	[186]	[637]	9	hSpCas9	negative selection	12030294
104777205	104777228	6	-	28162770	MONOMAC1	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.36193044512865813	[223]	[329]	3	hSpCas9	negative selection	12030295
104730375	104730398	6	-	28162770	MONOMAC1	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	1.6811220300056486	[70]	[260]	9	hSpCas9	negative selection	12030296
104796648	104796671	6	+	28162770	MONOMAC1	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.9036571525599193	[165]	[355]	8	hSpCas9	negative selection	12030297
104859627	104859650	6	-	28162770	OCIAML2	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-5.377520420850679	[14]	[1]	-9	hSpCas9	negative selection	12199656
104785156	104785179	6	+	28162770	OCIAML2	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.5664594934930588	[23]	[196]	5	hSpCas9	negative selection	12199657
104859567	104859590	6	-	28162770	OCIAML2	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	0.12033141610043813	[39]	[240]	1	hSpCas9	negative selection	12199658
104811368	104811391	6	-	28162770	OCIAML2	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.8290454627980732	[97]	[964]	7	hSpCas9	negative selection	12199659
104785297	104785320	6	+	28162770	OCIAML2	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	-0.743648319648577	[86]	[287]	-5	hSpCas9	negative selection	12199660
104777205	104777228	6	-	28162770	OCIAML2	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	-0.12633391732634436	[63]	[324]	-1	hSpCas9	negative selection	12199661
104730375	104730398	6	-	28162770	OCIAML2	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	0.8270507233985238	[23]	[235]	7	hSpCas9	negative selection	12199662
104796648	104796671	6	+	28162770	OCIAML2	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.5048874895584955	[51]	[408]	5	hSpCas9	negative selection	12199663
104859627	104859650	6	-	28162770	OCIAML3	viability	GCCGAGGATGGAGAGAGCGATGG	HACE1	ENSG00000085382	-1.594007640324163	[21]	[21]	-8	hSpCas9	negative selection	12369022
104785156	104785179	6	+	28162770	OCIAML3	viability	GGTCCTGGAGGTTCAAATGGAGG	HACE1	ENSG00000085382	0.31957760785836353	[42]	[161]	3	hSpCas9	negative selection	12369023
104859567	104859590	6	-	28162770	OCIAML3	viability	GCGCACCGTGGAGTTGCCCGAGG	HACE1	ENSG00000085382	1.9588426752432402	[52]	[621]	9	hSpCas9	negative selection	12369024
104811368	104811391	6	-	28162770	OCIAML3	viability	GTGCAGTGCTTGCTAGACAGTGG	HACE1	ENSG00000085382	0.8667219496475493	[201]	[1111]	7	hSpCas9	negative selection	12369025
104785297	104785320	6	+	28162770	OCIAML3	viability	GAGTGCCAAAGCAATTCCAGAGG	HACE1	ENSG00000085382	0.8316883404534029	[58]	[316]	7	hSpCas9	negative selection	12369026
104777205	104777228	6	-	28162770	OCIAML3	viability	GATATCCTGCTGGTTCACAGAGG	HACE1	ENSG00000085382	0.9365070763746166	[89]	[519]	7	hSpCas9	negative selection	12369027
104730375	104730398	6	-	28162770	OCIAML3	viability	GGGTTTGCTAATATCATGGGTGG	HACE1	ENSG00000085382	1.3583259260455225	[49]	[386]	9	hSpCas9	negative selection	12369028
104796648	104796671	6	+	28162770	OCIAML3	viability	ACAATACCATGTTTTCTCGGAGG	HACE1	ENSG00000085382	0.3807256010654069	[71]	[282]	3	hSpCas9	negative selection	12369029