Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:348980
• Symbol:HCN1
• Description:hyperpolarization activated cyclic nucleotide gated potassium channel 1

DataSource: http://genomecrispr.dkfz.de/#!/results/HCN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45695742	45695765	5	+	26472758	Jiyoye	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	4.494638222756212	[0]	[16]	9	hSpCas9	negative selection	69615
45695910	45695933	5	-	26472758	Jiyoye	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.04936275091997988	[172]	[134]	0	hSpCas9	negative selection	69616
45461859	45461882	5	+	26472758	Jiyoye	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.9096757220350566	[47]	[67]	6	hSpCas9	negative selection	69617
45695894	45695917	5	-	26472758	Jiyoye	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	4.729103476393235	[0]	[19]	9	hSpCas9	negative selection	69618
45695721	45695744	5	-	26472758	Jiyoye	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-2.5794041027318046	[213]	[26]	-9	hSpCas9	negative selection	69619
45396606	45396629	5	+	26472758	Jiyoye	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	-0.002468859002751733	[266]	[200]	0	hSpCas9	negative selection	69620
45396552	45396575	5	+	26472758	Jiyoye	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.947743762868576	[43]	[63]	6	hSpCas9	negative selection	69621
45396522	45396545	5	+	26472758	Jiyoye	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-1.4672937364102676	[43]	[11]	-7	hSpCas9	negative selection	69622
45396491	45396514	5	-	26472758	Jiyoye	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	-0.4768008221546432	[202]	[109]	-3	hSpCas9	negative selection	69623
45695929	45695952	5	+	26472758	Jiyoye	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.9435577017819681	[150]	[218]	6	hSpCas9	negative selection	69624
45695742	45695765	5	+	26472758	KBM7	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-3.7649115685976655	[14,39]	[0,0]	-9	hSpCas9	negative selection	260733
45695910	45695933	5	-	26472758	KBM7	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.8253317075669238	[744,1381]	[1398,486]	8	hSpCas9	negative selection	260734
45461859	45461882	5	+	26472758	KBM7	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	1.2787310377867547	[114,112]	[100,156]	9	hSpCas9	negative selection	260735
45695894	45695917	5	-	26472758	KBM7	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	1.0185053072143648	[34,39]	[42,29]	9	hSpCas9	negative selection	260736
45695721	45695744	5	-	26472758	KBM7	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.284717790049075	[502,448]	[95,87]	-7	hSpCas9	negative selection	260737
45396606	45396629	5	+	26472758	KBM7	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.3104755594237435	[830,566]	[501,311]	3	hSpCas9	negative selection	260738
45396552	45396575	5	+	26472758	KBM7	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.04475890018299865	[460,463]	[206,241]	0	hSpCas9	negative selection	260739
45396522	45396545	5	+	26472758	KBM7	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-0.11652529966748348	[92,145]	[38,65]	-1	hSpCas9	negative selection	260740
45396491	45396514	5	-	26472758	KBM7	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.3648759359298702	[498,617]	[352,334]	4	hSpCas9	negative selection	260741
45695929	45695952	5	+	26472758	KBM7	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	1.0712649610909133	[407,780]	[352,837]	9	hSpCas9	negative selection	260742
45695742	45695765	5	+	26472758	Raji	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	451851
45695910	45695933	5	-	26472758	Raji	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.14535138557261978	[299]	[76]	1	hSpCas9	negative selection	451852
45461859	45461882	5	+	26472758	Raji	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.785455440486237	[49]	[19]	7	hSpCas9	negative selection	451853
45695894	45695917	5	-	26472758	Raji	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	2.6923460360947558	[3]	[5]	9	hSpCas9	negative selection	451854
45695721	45695744	5	-	26472758	Raji	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-2.040515159738714	[194]	[10]	-8	hSpCas9	negative selection	451855
45396606	45396629	5	+	26472758	Raji	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.5987244019656407	[312]	[109]	5	hSpCas9	negative selection	451856
45396552	45396575	5	+	26472758	Raji	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	-0.4134486279278411	[263]	[45]	-3	hSpCas9	negative selection	451857
45396522	45396545	5	+	26472758	Raji	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	0.4679732506300669	[80]	[25]	4	hSpCas9	negative selection	451858
45396491	45396514	5	-	26472758	Raji	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.35373920006076315	[289]	[85]	3	hSpCas9	negative selection	451859
45695929	45695952	5	+	26472758	Raji	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	-0.18945357855093253	[284]	[57]	-2	hSpCas9	negative selection	451860
45695742	45695765	5	+	26472758	K562	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-3.1248150819992726	[30]	[2]	-8	hSpCas9	negative selection	642969
45695910	45695933	5	-	26472758	K562	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.16949560859714585	[493]	[468]	1	hSpCas9	negative selection	642970
45461859	45461882	5	+	26472758	K562	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	1.3141890059706212	[110]	[232]	9	hSpCas9	negative selection	642971
45695894	45695917	5	-	26472758	K562	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	0.07776885825699553	[54]	[48]	0	hSpCas9	negative selection	642972
45695721	45695744	5	-	26472758	K562	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-4.916893143471158	[500]	[13]	-9	hSpCas9	negative selection	642973
45396606	45396629	5	+	26472758	K562	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.35445852800780564	[592]	[639]	2	hSpCas9	negative selection	642974
45396552	45396575	5	+	26472758	K562	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.247941794230144	[408]	[409]	2	hSpCas9	negative selection	642975
45396522	45396545	5	+	26472758	K562	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	0.23514091407843596	[155]	[154]	1	hSpCas9	negative selection	642976
45396491	45396514	5	-	26472758	K562	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	-0.2779234194618687	[664]	[462]	-2	hSpCas9	negative selection	642977
45695929	45695952	5	+	26472758	K562	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	1.3111135720001033	[390]	[818]	9	hSpCas9	negative selection	642978
45303692	45303715	5	-	26627737	DLD1	viability	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.31235786291690093	[415]	[111,132,74]	-3	hSpCas9	negative selection	828921
45353099	45353122	5	-	26627737	DLD1	viability	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.17518756452171758	[484]	[232,154,130]	1	hSpCas9	negative selection	828922
45396527	45396550	5	+	26627737	DLD1	viability	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.0037333134176199545	[269]	[122,79,53]	0	hSpCas9	negative selection	828924
45461908	45461931	5	+	26627737	DLD1	viability	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.07073526637318667	[338]	[110,152,48]	0	hSpCas9	negative selection	828925
45645337	45645360	5	-	26627737	DLD1	viability	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.09479378106924202	[597]	[89,296,213]	1	hSpCas9	negative selection	828926
45696052	45696075	5	-	26627737	DLD1	viability	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.5575432149033708	[566]	[238,291,253]	5	hSpCas9	negative selection	828927
45303692	45303715	5	-	26627737	GBM cells	viability after 5 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.2716025162106913	[304]	[104,165]	-4	hSpCas9	negative selection	911236
45353099	45353122	5	-	26627737	GBM cells	viability after 5 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	-0.11696916672096938	[273]	[119,150]	-2	hSpCas9	negative selection	911237
45396527	45396550	5	+	26627737	GBM cells	viability after 5 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.8720606114454194	[185]	[49,58]	-8	hSpCas9	negative selection	911239
45461908	45461931	5	+	26627737	GBM cells	viability after 5 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.2255134094969455	[184]	[108,122]	3	hSpCas9	negative selection	911240
45645337	45645360	5	-	26627737	GBM cells	viability after 5 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.4893102616574698	[264]	[203,194]	7	hSpCas9	negative selection	911241
45696052	45696075	5	-	26627737	GBM cells	viability after 5 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.32414059497706615	[387]	[255,264]	5	hSpCas9	negative selection	911242
45303692	45303715	5	-	26627737	GBM cells	viability after 13 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.08013682078248427	[304]	[139,169]	-1	hSpCas9	negative selection	993551
45353099	45353122	5	-	26627737	GBM cells	viability after 13 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	-0.23293538468776906	[273]	[163,95]	-3	hSpCas9	negative selection	993552
45396527	45396550	5	+	26627737	GBM cells	viability after 13 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.9887963751376415	[185]	[30,66]	-8	hSpCas9	negative selection	993554
45461908	45461931	5	+	26627737	GBM cells	viability after 13 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.8207823552412881	[184]	[232,131]	8	hSpCas9	negative selection	993555
45645337	45645360	5	-	26627737	GBM cells	viability after 13 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.8448380357314109	[264]	[335,194]	8	hSpCas9	negative selection	993556
45696052	45696075	5	-	26627737	GBM cells	viability after 13 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.8391470726258112	[387]	[444,320]	8	hSpCas9	negative selection	993557
45303692	45303715	5	-	26627737	GBM cells	viability after 21 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.12013322963687345	[304]	[177,181]	1	hSpCas9	negative selection	1075866
45353099	45353122	5	-	26627737	GBM cells	viability after 21 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	-0.31411774421223976	[273]	[125,113]	-3	hSpCas9	negative selection	1075867
45396527	45396550	5	+	26627737	GBM cells	viability after 21 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.12131881999708227	[185]	[106,79]	-1	hSpCas9	negative selection	1075869
45461908	45461931	5	+	26627737	GBM cells	viability after 21 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.3532283821246649	[184]	[130,125]	3	hSpCas9	negative selection	1075870
45645337	45645360	5	-	26627737	GBM cells	viability after 21 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.005088547854373987	[264]	[144,143]	0	hSpCas9	negative selection	1075871
45696052	45696075	5	-	26627737	GBM cells	viability after 21 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.5908827501891794	[387]	[352,284]	6	hSpCas9	negative selection	1075872
45303692	45303715	5	-	26627737	RPE1	viability after 9 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.5335655475845558	[586]	[74,193]	-4	hSpCas9	negative selection	1158181
45353099	45353122	5	-	26627737	RPE1	viability after 9 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.42741772672431255	[651]	[215,349]	3	hSpCas9	negative selection	1158182
45396527	45396550	5	+	26627737	RPE1	viability after 9 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.05001077667282215	[849]	[91,469]	0	hSpCas9	negative selection	1158184
45461908	45461931	5	+	26627737	RPE1	viability after 9 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.816451372991717	[906]	[155,167]	-5	hSpCas9	negative selection	1158185
45645337	45645360	5	-	26627737	RPE1	viability after 9 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.3598775502574939	[1605]	[441,326]	-3	hSpCas9	negative selection	1158186
45696052	45696075	5	-	26627737	RPE1	viability after 9 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.2643666993031514	[1450]	[511,588]	2	hSpCas9	negative selection	1158187
45303692	45303715	5	-	26627737	RPE1	viability after 12 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.4491778101101861	[586]	[64,168]	-3	hSpCas9	negative selection	1240496
45353099	45353122	5	-	26627737	RPE1	viability after 12 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.2517809891518357	[651]	[108,313]	1	hSpCas9	negative selection	1240497
45396527	45396550	5	+	26627737	RPE1	viability after 12 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.4286316372926382	[849]	[200,419]	3	hSpCas9	negative selection	1240499
45461908	45461931	5	+	26627737	RPE1	viability after 12 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.3674775464518685	[906]	[184,192]	-3	hSpCas9	negative selection	1240500
45645337	45645360	5	-	26627737	RPE1	viability after 12 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.8300295507175602	[1605]	[283,198]	-5	hSpCas9	negative selection	1240501
45696052	45696075	5	-	26627737	RPE1	viability after 12 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.598758700256855	[1450]	[602,576]	4	hSpCas9	negative selection	1240502
45303692	45303715	5	-	26627737	RPE1	viability after 15 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.04771940777540523	[586]	[135,205]	0	hSpCas9	negative selection	1322811
45353099	45353122	5	-	26627737	RPE1	viability after 15 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.7526155450999662	[651]	[324,296]	4	hSpCas9	negative selection	1322812
45396527	45396550	5	+	26627737	RPE1	viability after 15 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.36958344181929714	[849]	[273,345]	2	hSpCas9	negative selection	1322814
45461908	45461931	5	+	26627737	RPE1	viability after 15 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.4766530934712462	[906]	[190,177]	-3	hSpCas9	negative selection	1322815
45645337	45645360	5	-	26627737	RPE1	viability after 15 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-1.367241376766737	[1605]	[85,262]	-7	hSpCas9	negative selection	1322816
45696052	45696075	5	-	26627737	RPE1	viability after 15 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.0992898228156398	[1450]	[540,341]	0	hSpCas9	negative selection	1322817
45303692	45303715	5	-	26627737	RPE1	viability after 18 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.05620625515295952	[586]	[89,218]	0	hSpCas9	negative selection	1405126
45353099	45353122	5	-	26627737	RPE1	viability after 18 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.16555801178820595	[651]	[192,201]	1	hSpCas9	negative selection	1405127
45396527	45396550	5	+	26627737	RPE1	viability after 18 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.5512566654175767	[849]	[208,471]	3	hSpCas9	negative selection	1405129
45461908	45461931	5	+	26627737	RPE1	viability after 18 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.05305309759279267	[906]	[233,237]	0	hSpCas9	negative selection	1405130
45645337	45645360	5	-	26627737	RPE1	viability after 18 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-1.0483083271857463	[1605]	[196,222]	-6	hSpCas9	negative selection	1405131
45696052	45696075	5	-	26627737	RPE1	viability after 18 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.3247575841826288	[1450]	[371,616]	2	hSpCas9	negative selection	1405132
45303692	45303715	5	-	26627737	HeLa	viability after 8 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.5237165431874484	[553]	[201,146,161]	-5	hSpCas9	negative selection	1487441
45353099	45353122	5	-	26627737	HeLa	viability after 8 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	-0.4645013111250112	[436]	[65,154,173]	-4	hSpCas9	negative selection	1487442
45396527	45396550	5	+	26627737	HeLa	viability after 8 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.28412586355503844	[178]	[158,49,89]	2	hSpCas9	negative selection	1487444
45461908	45461931	5	+	26627737	HeLa	viability after 8 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.3967089205416201	[408]	[102,19,265]	-4	hSpCas9	negative selection	1487445
45645337	45645360	5	-	26627737	HeLa	viability after 8 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	1.4296607351049855	[157]	[212,211,139]	8	hSpCas9	negative selection	1487446
45696052	45696075	5	-	26627737	HeLa	viability after 8 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	-0.1745404599516539	[827]	[433,333,221]	-2	hSpCas9	negative selection	1487447
45303692	45303715	5	-	26627737	HeLa	viability after 12 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.8752199046100544	[553]	[135,150,84]	-7	hSpCas9	negative selection	1569756
45353099	45353122	5	-	26627737	HeLa	viability after 12 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	-0.15714468038932417	[436]	[89,225,160]	-1	hSpCas9	negative selection	1569757
45396527	45396550	5	+	26627737	HeLa	viability after 12 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.2270058009037007	[178]	[58,85,113]	2	hSpCas9	negative selection	1569759
45461908	45461931	5	+	26627737	HeLa	viability after 12 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.9543931933411127	[408]	[100,87,72]	-7	hSpCas9	negative selection	1569760
45645337	45645360	5	-	26627737	HeLa	viability after 12 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	1.1506602273202506	[157]	[160,138,135]	8	hSpCas9	negative selection	1569761
45696052	45696075	5	-	26627737	HeLa	viability after 12 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.2270835807560443	[827]	[501,357,348]	2	hSpCas9	negative selection	1569762
45303692	45303715	5	-	26627737	HeLa	viability after 15 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.6058703242166882	[553]	[52,193,202]	-5	hSpCas9	negative selection	1652071
45353099	45353122	5	-	26627737	HeLa	viability after 15 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	-0.29065555082523464	[436]	[163,175,91]	-3	hSpCas9	negative selection	1652072
45396527	45396550	5	+	26627737	HeLa	viability after 15 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.7918118328003833	[178]	[100,112,167]	6	hSpCas9	negative selection	1652074
45461908	45461931	5	+	26627737	HeLa	viability after 15 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.36365446725867656	[408]	[211,107,61]	-3	hSpCas9	negative selection	1652075
45645337	45645360	5	-	26627737	HeLa	viability after 15 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	1.2993602071554704	[157]	[109,225,137]	8	hSpCas9	negative selection	1652076
45696052	45696075	5	-	26627737	HeLa	viability after 15 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.07230304511064034	[827]	[479,173,411]	0	hSpCas9	negative selection	1652077
45303692	45303715	5	-	26627737	HeLa	viability after 18 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.6112397255112849	[553]	[38,154,202]	-5	hSpCas9	negative selection	1734386
45353099	45353122	5	-	26627737	HeLa	viability after 18 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	-0.2958905173680244	[436]	[111,141,91]	-3	hSpCas9	negative selection	1734387
45396527	45396550	5	+	26627737	HeLa	viability after 18 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.8138578560718686	[178]	[71,92,167]	6	hSpCas9	negative selection	1734389
45461908	45461931	5	+	26627737	HeLa	viability after 18 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.2522190415144606	[408]	[157,94,61]	-2	hSpCas9	negative selection	1734390
45645337	45645360	5	-	26627737	HeLa	viability after 18 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	1.2453580850931023	[157]	[64,183,137]	8	hSpCas9	negative selection	1734391
45696052	45696075	5	-	26627737	HeLa	viability after 18 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.05010541127117607	[827]	[313,140,411]	0	hSpCas9	negative selection	1734392
45303692	45303715	5	-	26627737	HCT116	viability after 6 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	1.591625168283706	[551]	[626,59]	7	hSpCas9	negative selection	1816701
45353099	45353122	5	-	26627737	HCT116	viability after 6 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	2.7332060977652612	[310]	[152,419]	9	hSpCas9	negative selection	1816702
45396527	45396550	5	+	26627737	HCT116	viability after 6 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.6764424946072249	[376]	[173,50]	4	hSpCas9	negative selection	1816704
45461908	45461931	5	+	26627737	HCT116	viability after 6 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-2.7823960974212327	[598]	[23,7]	-9	hSpCas9	negative selection	1816705
45645337	45645360	5	-	26627737	HCT116	viability after 6 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.17491276780795495	[419]	[62,55]	-1	hSpCas9	negative selection	1816706
45696052	45696075	5	-	26627737	HCT116	viability after 6 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	1.2681911224326372	[636]	[246,237]	6	hSpCas9	negative selection	1816707
45303692	45303715	5	-	26627737	HCT116	viability after 8 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.6236429848300931	[177]	[167,161,123]	6	hSpCas9	negative selection	1899016
45353099	45353122	5	-	26627737	HCT116	viability after 8 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.1860987979001864	[212]	[175,145,79]	2	hSpCas9	negative selection	1899017
45396527	45396550	5	+	26627737	HCT116	viability after 8 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.10721372089595227	[153]	[65,81,87]	-1	hSpCas9	negative selection	1899019
45461908	45461931	5	+	26627737	HCT116	viability after 8 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.1332872877161595	[314]	[166,155,151]	-1	hSpCas9	negative selection	1899020
45645337	45645360	5	-	26627737	HCT116	viability after 8 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.7311421007335883	[420]	[218,88,112]	-7	hSpCas9	negative selection	1899021
45696052	45696075	5	-	26627737	HCT116	viability after 8 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	-0.26463530246417344	[571]	[249,284,251]	-3	hSpCas9	negative selection	1899022
45303692	45303715	5	-	26627737	HCT116	viability after 9 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-1.8686674948298398	[551]	[55,27]	-8	hSpCas9	negative selection	1981331
45353099	45353122	5	-	26627737	HCT116	viability after 9 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.3257830833909017	[310]	[150,66]	2	hSpCas9	negative selection	1981332
45396527	45396550	5	+	26627737	HCT116	viability after 9 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.7163530897345943	[376]	[194,141]	5	hSpCas9	negative selection	1981334
45461908	45461931	5	+	26627737	HCT116	viability after 9 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.14582225871811583	[598]	[162,129]	-1	hSpCas9	negative selection	1981335
45645337	45645360	5	-	26627737	HCT116	viability after 9 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.7492684296623084	[419]	[154,214]	5	hSpCas9	negative selection	1981336
45696052	45696075	5	-	26627737	HCT116	viability after 9 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	1.7915668186687932	[636]	[432,711]	9	hSpCas9	negative selection	1981337
45303692	45303715	5	-	26627737	HCT116	viability after 12 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.5505435557043805	[177]	[87,205,122]	5	hSpCas9	negative selection	2063646
45353099	45353122	5	-	26627737	HCT116	viability after 12 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.13581350500739342	[212]	[84,151,135]	1	hSpCas9	negative selection	2063647
45396527	45396550	5	+	26627737	HCT116	viability after 12 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.15634779417539524	[153]	[108,92,66]	1	hSpCas9	negative selection	2063649
45461908	45461931	5	+	26627737	HCT116	viability after 12 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.3945282880541306	[314]	[166,117,88]	-4	hSpCas9	negative selection	2063650
45645337	45645360	5	-	26627737	HCT116	viability after 12 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.48668350004646393	[420]	[192,132,143]	-5	hSpCas9	negative selection	2063651
45696052	45696075	5	-	26627737	HCT116	viability after 12 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.051324939474020725	[571]	[161,286,497]	0	hSpCas9	negative selection	2063652
45303692	45303715	5	-	26627737	HCT116	viability after 15 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.4459657668985384	[177]	[134,122,158]	4	hSpCas9	negative selection	2145961
45353099	45353122	5	-	26627737	HCT116	viability after 15 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.2704348582383017	[212]	[103,157,174]	2	hSpCas9	negative selection	2145962
45396527	45396550	5	+	26627737	HCT116	viability after 15 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.7075178916498379	[153]	[73,147,201]	6	hSpCas9	negative selection	2145964
45461908	45461931	5	+	26627737	HCT116	viability after 15 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.5386205428316861	[314]	[309,214,268]	5	hSpCas9	negative selection	2145965
45645337	45645360	5	-	26627737	HCT116	viability after 15 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.9913037409871037	[420]	[117,172,73]	-7	hSpCas9	negative selection	2145966
45696052	45696075	5	-	26627737	HCT116	viability after 15 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	-0.22995055722301228	[571]	[234,252,345]	-2	hSpCas9	negative selection	2145967
45303692	45303715	5	-	26627737	HCT116	viability after 18 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.5179984641109545	[177]	[160,104,103]	4	hSpCas9	negative selection	2228276
45353099	45353122	5	-	26627737	HCT116	viability after 18 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.4224884289747197	[212]	[79,144,190]	3	hSpCas9	negative selection	2228277
45396527	45396550	5	+	26627737	HCT116	viability after 18 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.2682162165348837	[153]	[40,100,127]	2	hSpCas9	negative selection	2228279
45461908	45461931	5	+	26627737	HCT116	viability after 18 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.6128494648126616	[314]	[151,92,51]	-5	hSpCas9	negative selection	2228280
45645337	45645360	5	-	26627737	HCT116	viability after 18 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-1.7562348057496087	[420]	[72,69,35]	-8	hSpCas9	negative selection	2228281
45696052	45696075	5	-	26627737	HCT116	viability after 18 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.14990629658942067	[571]	[230,238,461]	1	hSpCas9	negative selection	2228282
45571726	45571749	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTTAG	HCN1	ENSG00000164588	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409599
45684612	45684635	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGTAGGCCAAGGTGGG	HCN1	ENSG00000164588	0.5553943551630764	[8,10]	[3,1]	2	dCas9-VP64	positive selection	2418535
45502233	45502256	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGGCGGGCGGATCATCTGAGG	HCN1	ENSG00000164588	1.1682084451349461	[40,6]	[12,9]	4	dCas9-VP64	positive selection	2431573
45363599	45363622	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAGTTGAGATTTGAATGTGG	HCN1	ENSG00000164588	2.332962177472176	[219,61]	[294,4]	7	dCas9-VP64	positive selection	2464833
45571726	45571749	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTTAG	HCN1	ENSG00000164588	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504854
45684612	45684635	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGTAGGCCAAGGTGGG	HCN1	ENSG00000164588	-0.8671691922358802	[189,124]	[32,22]	-7	dCas9-VP64	positive selection	2513790
45502233	45502256	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGGCGGGCGGATCATCTGAGG	HCN1	ENSG00000164588	1.094181115939585	[31,116]	[73,29]	7	dCas9-VP64	positive selection	2526828
45363599	45363622	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAGTTGAGATTTGAATGTGG	HCN1	ENSG00000164588	0.2251896209207659	[80,158]	[68,22]	1	dCas9-VP64	positive selection	2560088
45461909	45461932	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.1601079173479491	[4,4]	[5,3]	3	hSpCas9	positive selection	2992834
45645337	45645360	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.5345862559938265	[3,4]	[4,5]	9	hSpCas9	positive selection	2992835
45695903	45695926	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGTGCTTCAAGGTGGACGGCGG	HCN1	ENSG00000164588	0.5852535425854776	[5,5]	[5,8]	9	hSpCas9	positive selection	2992836
45645277	45645300	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAGTTTACAAGACAGCCAGGG	HCN1	ENSG00000164588	-0.4654203206619439	[4,4]	[4,0]	-6	hSpCas9	positive selection	2992837
45461909	45461932	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.18471830781415471	[4,4]	[5,2]	3	hSpCas9	positive selection	3060692
45645337	45645360	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.26626362177197943	[3,3]	[5,2]	5	hSpCas9	positive selection	3060693
45695903	45695926	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGTGCTTCAAGGTGGACGGCGG	HCN1	ENSG00000164588	-0.025650141525776216	[5,5]	[4,2]	0	hSpCas9	positive selection	3060694
45645277	45645300	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAGTTTACAAGACAGCCAGGG	HCN1	ENSG00000164588	0.365019783158665	[4,4]	[3,3]	6	hSpCas9	positive selection	3060695
45461908	45461931		+	24336571	A375	resistance to PLX after 7 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.04530543624320701	[12,12]	[12,12]	1	hSpCas9	positive selection	3118568
45645445	45645468		+	24336571	A375	resistance to PLX after 7 days	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.005211110356807103	[15,16]	[15,15]	0	hSpCas9	positive selection	3118569
45461887	45461910		-	24336571	A375	resistance to PLX after 7 days	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.4447639310237583	[9,11]	[7,6]	-9	hSpCas9	positive selection	3118570
45461908	45461931		+	24336571	A375	resistance to PLX after 14 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.9444446527678477	[17,11]	[15,10]	7	hSpCas9	positive selection	3176361
45645445	45645468		+	24336571	A375	resistance to PLX after 14 days	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.6548955388877071	[12,24]	[4,4]	-7	hSpCas9	positive selection	3176362
45461887	45461910		-	24336571	A375	resistance to PLX after 14 days	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.17348041921244006	[7,13]	[2,5]	-2	hSpCas9	positive selection	3176363
45461908	45461931		+	24336571	A375	viability after 7 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.12398667784162584	[11]	[12,12]	2	hSpCas9	negative selection	3234154
45645445	45645468		+	24336571	A375	viability after 7 days	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.10943019527341497	[18]	[15,16]	-1	hSpCas9	negative selection	3234155
45461887	45461910		-	24336571	A375	viability after 7 days	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.12407118080119248	[11]	[9,11]	-2	hSpCas9	negative selection	3234156
45461908	45461931		+	24336571	A375	viability after 14 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.3607455744875129	[11]	[17,11]	4	hSpCas9	negative selection	3291947
45645445	45645468		+	24336571	A375	viability after 14 days	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.11998581918697149	[18]	[12,24]	1	hSpCas9	negative selection	3291948
45461887	45461910		-	24336571	A375	viability after 14 days	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.06416745333347193	[11]	[7,13]	0	hSpCas9	negative selection	3291949
45461887	45461910	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.272060939499944	[156,95]	[0,0]	1	hSpCas9	positive selection	3353083
45353185	45353208	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.04685381343060881	[163,131]	[0,0]	0	hSpCas9	positive selection	3353084
45396509	45396532	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	3.0717705582897583	[43,46]	[0,3]	8	hSpCas9	positive selection	3353085
45645445	45645468	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	4.779278914641191	[272,272]	[48,48]	9	hSpCas9	positive selection	3372274
45396576	45396599	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.20210540719146217	[175,175]	[0,0]	-1	hSpCas9	positive selection	3372275
45645260	45645283	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-1.1520647246918665	[339,339]	[0,0]	-7	hSpCas9	positive selection	3372276
45461908	45461931	5	+	26780180	HT29	viability (Avana library 4 designs)	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.11953367667972	[]	[]	0	hSpCas9	negative selection	3430093
45645337	45645360	5	-	26780180	HT29	viability (Avana library 4 designs)	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.266061019992448	[]	[]	0	hSpCas9	negative selection	3430094
45695903	45695926	5	-	26780180	HT29	viability (Avana library 4 designs)	GTGTGCTTCAAGGTGGACGGCGG	HCN1	ENSG00000164588	-0.105858124233032	[]	[]	-2	hSpCas9	negative selection	3430095
45645277	45645300	5	-	26780180	HT29	viability (Avana library 4 designs)	TGAAGTTTACAAGACAGCCAGGG	HCN1	ENSG00000164588	1.0583581298253	[]	[]	4	hSpCas9	negative selection	3430096
45645337	45645360	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-2.39154191746758	[]	[]	-3	hSpCas9	negative selection	3515086
45645277	45645300	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGTTTACAAGACAGCCAGGG	HCN1	ENSG00000164588	0.960796841790749	[]	[]	1	hSpCas9	negative selection	3515087
45695903	45695926	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTGCTTCAAGGTGGACGGCGG	HCN1	ENSG00000164588	5.49567161011836	[]	[]	8	hSpCas9	negative selection	3515088
45461908	45461931	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.126540435824305	[]	[]	0	hSpCas9	negative selection	3515089
45645531	45645554	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAAGAATGTGATTCCAACTGG	HCN1	ENSG00000164588	-1.785815932995	[]	[]	-2	hSpCas9	negative selection	3515090
45695742	45695765	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.994525359462216	[]	[]	-1	hSpCas9	negative selection	3515091
45645337	45645360	5	-	26780180	A375	viability (Avana lentiGuide)	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-3.28105340195382	[]	[]	-6	hSpCas9	negative selection	3623745
45645277	45645300	5	-	26780180	A375	viability (Avana lentiGuide)	TGAAGTTTACAAGACAGCCAGGG	HCN1	ENSG00000164588	0.725586477391743	[]	[]	0	hSpCas9	negative selection	3623746
45695903	45695926	5	-	26780180	A375	viability (Avana lentiGuide)	GTGTGCTTCAAGGTGGACGGCGG	HCN1	ENSG00000164588	-0.219607036918816	[]	[]	0	hSpCas9	negative selection	3623747
45461908	45461931	5	+	26780180	A375	viability (Avana lentiGuide)	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-2.68608680086406	[]	[]	-5	hSpCas9	negative selection	3623748
45645531	45645554	5	+	26780180	A375	viability (Avana lentiGuide)	GTAAAGAATGTGATTCCAACTGG	HCN1	ENSG00000164588	-8.04676470032025	[]	[]	-9	hSpCas9	negative selection	3623749
45695742	45695765	5	+	26780180	A375	viability (Avana lentiGuide)	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	6.53342399392032	[]	[]	5	hSpCas9	negative selection	3623750
45645337	45645360	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.7183579160229401	[4]	[1,2]	-8	hSpCas9	positive selection	3732404
45645277	45645300	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGTTTACAAGACAGCCAGGG	HCN1	ENSG00000164588	0.021207900085135872	[5]	[5,5]	0	hSpCas9	positive selection	3732405
45695903	45695926	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTGCTTCAAGGTGGACGGCGG	HCN1	ENSG00000164588	0.14771968006461794	[5]	[6,5]	4	hSpCas9	positive selection	3732406
45461908	45461931	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.07727276372757758	[6]	[6,6]	2	hSpCas9	positive selection	3732407
45645531	45645554	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAAGAATGTGATTCCAACTGG	HCN1	ENSG00000164588	-0.2987231534987098	[5]	[4,4]	-4	hSpCas9	positive selection	3732408
45695742	45695765	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.0414628256405441	[4]	[4,4]	0	hSpCas9	positive selection	3732409
45645337	45645360	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.14464811825073667	[6]	[4,4]	-2	hSpCas9	positive selection	3841011
45645277	45645300	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGTTTACAAGACAGCCAGGG	HCN1	ENSG00000164588	-0.460879546070309	[5]	[4,2]	-5	hSpCas9	positive selection	3841012
45695903	45695926	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTGCTTCAAGGTGGACGGCGG	HCN1	ENSG00000164588	0.09957238769013732	[6]	[6,6]	2	hSpCas9	positive selection	3841013
45461908	45461931	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.234172422319339	[6]	[6,6]	6	hSpCas9	positive selection	3841014
45645531	45645554	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAAGAATGTGATTCCAACTGG	HCN1	ENSG00000164588	0.3241635877795334	[5]	[6,5]	8	hSpCas9	positive selection	3841015
45695742	45695765	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.030902370932008642	[5]	[5,3]	0	hSpCas9	positive selection	3841016
45353185	45353208	5	+	26780180	A375	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	1.48294008962187	[]	[]	8	hSpCas9	negative selection	3947074
45645445	45645468	5	+	26780180	A375	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	1.00644701915369	[]	[]	4	hSpCas9	negative selection	3947075
45396576	45396599	5	+	26780180	A375	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.527022460941213	[]	[]	1	hSpCas9	negative selection	3947076
45645260	45645283	5	+	26780180	A375	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	2.58597587023529	[]	[]	9	hSpCas9	negative selection	3947077
45396509	45396532	5	+	26780180	A375	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.842909135602091	[]	[]	3	hSpCas9	negative selection	3947078
45461887	45461910	5	-	26780180	A375	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	1.42234511230434	[]	[]	7	hSpCas9	negative selection	3947079
45353185	45353208	5	+	26780180	HT29	viability (GeCKOv2 library)	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	2.00196939232817	[]	[]	9	hSpCas9	negative selection	4055040
45645445	45645468	5	+	26780180	HT29	viability (GeCKOv2 library)	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.566785115878302	[]	[]	2	hSpCas9	negative selection	4055041
45396576	45396599	5	+	26780180	HT29	viability (GeCKOv2 library)	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.908751134850319	[]	[]	4	hSpCas9	negative selection	4055042
45645260	45645283	5	+	26780180	HT29	viability (GeCKOv2 library)	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	2.78807611851575	[]	[]	9	hSpCas9	negative selection	4055043
45396509	45396532	5	+	26780180	HT29	viability (GeCKOv2 library)	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.846043207181741	[]	[]	3	hSpCas9	negative selection	4055044
45461887	45461910	5	-	26780180	HT29	viability (GeCKOv2 library)	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	2.23675189868949	[]	[]	9	hSpCas9	negative selection	4055045
45461908	45461931	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.2583052520732497	[3]	[1,3]	6	hSpCas9	positive selection	4142000
45645445	45645468	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.12962864394822363	[3]	[2,2]	3	hSpCas9	positive selection	4142001
45461887	45461910	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.17152685946738813	[3]	[1,1]	-4	hSpCas9	positive selection	4142002
45461908	45461931	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	-0.08297989183882927	[3]	[3,1,0,0]	-1	hSpCas9	positive selection	4206022
45645445	45645468	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.002681810661640527	[4]	[3,3,1,0]	0	hSpCas9	positive selection	4206023
45461887	45461910	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.0790294787729614	[1]	[0,0,1,0]	0	hSpCas9	positive selection	4206024
45461887	45461910	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.08524807398802284	[2]	[2,1]	-2	hSpCas9	positive selection	4274652
45353185	45353208	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.047705676526927476	[3]	[2,2]	1	hSpCas9	positive selection	4274653
45396509	45396532	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.1946747255406558	[2]	[1,1]	4	hSpCas9	positive selection	4274654
45645445	45645468	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.09163706208441524	[3]	[3,1]	-2	hSpCas9	positive selection	4338913
45396576	45396599	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.005001498425922499	[3]	[3,1]	0	hSpCas9	positive selection	4338914
45645260	45645283	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.43960743585506995	[5]	[2,2]	-7	hSpCas9	positive selection	4338915
45461887	45461909	5	-	27760321	OCIAML3	viability	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.34713068740812014	[175,181]	[118,256]	4	hSpCas9	negative selection	4406349
45645261	45645283	5	+	27760321	OCIAML3	viability	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.08571331237817764	[647,553]	[365,539]	-1	hSpCas9	negative selection	4406350
45695743	45695765	5	+	27760321	OCIAML3	viability	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.3831347004128029	[664,531]	[348,366]	-4	hSpCas9	negative selection	4406351
45695812	45695834	5	+	27760321	OCIAML3	viability	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.1633406062784245	[850,707]	[592,792]	2	hSpCas9	negative selection	4406352
45695910	45695932	5	-	27760321	OCIAML3	viability	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.25682220897884833	[604,524]	[464,606]	3	hSpCas9	negative selection	4406353
45461887	45461909	5	-	27760321	OCIAML2	viability	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.3524609512642267	[175,181]	[100,130]	-4	hSpCas9	negative selection	4489812
45645261	45645283	5	+	27760321	OCIAML2	viability	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.17458293371654576	[647,553]	[420,712]	2	hSpCas9	negative selection	4489813
45695743	45695765	5	+	27760321	OCIAML2	viability	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.28654807795026405	[664,531]	[385,405]	-4	hSpCas9	negative selection	4489814
45695812	45695834	5	+	27760321	OCIAML2	viability	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.03085080164507492	[850,707]	[612,678]	0	hSpCas9	negative selection	4489815
45695910	45695932	5	-	27760321	OCIAML2	viability	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.8046622455766363	[604,524]	[640,1000]	9	hSpCas9	negative selection	4489816
45461887	45461909	5	-	27760321	MV411	viability	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-1.5692152252400602	[175,181]	[29,54]	-7	hSpCas9	negative selection	4573275
45645261	45645283	5	+	27760321	MV411	viability	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.9527104114400126	[647,553]	[783,736]	7	hSpCas9	negative selection	4573276
45695743	45695765	5	+	27760321	MV411	viability	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.36276390388624946	[664,531]	[244,395]	-3	hSpCas9	negative selection	4573277
45695812	45695834	5	+	27760321	MV411	viability	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	-0.3986547498542848	[850,707]	[320,489]	-3	hSpCas9	negative selection	4573278
45695910	45695932	5	-	27760321	MV411	viability	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	1.3823528646365038	[604,524]	[1116,747]	8	hSpCas9	negative selection	4573279
45461887	45461909	5	-	27760321	HL60	viability	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.7501617284230728	[175,181]	[81,92]	-7	hSpCas9	negative selection	4656738
45645261	45645283	5	+	27760321	HL60	viability	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.24558878422993713	[647,553]	[537,624]	3	hSpCas9	negative selection	4656739
45695743	45695765	5	+	27760321	HL60	viability	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.5359605197106647	[664,531]	[678,731]	6	hSpCas9	negative selection	4656740
45695812	45695834	5	+	27760321	HL60	viability	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	-0.012464267043801214	[850,707]	[664,589]	0	hSpCas9	negative selection	4656741
45695910	45695932	5	-	27760321	HL60	viability	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.23897198033453781	[604,524]	[569,514]	3	hSpCas9	negative selection	4656742
45461887	45461909	5	-	27760321	HT1080	viability	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	1.2934609173761076	[181,141]	[277,26]	7	hSpCas9	negative selection	4740201
45645261	45645283	5	+	27760321	HT1080	viability	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.10138096450817968	[553,432]	[240,177]	0	hSpCas9	negative selection	4740202
45695743	45695765	5	+	27760321	HT1080	viability	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.5183964482264537	[531,414]	[103,161]	-2	hSpCas9	negative selection	4740203
45695812	45695834	5	+	27760321	HT1080	viability	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.3723555780154575	[707,552]	[380,263]	2	hSpCas9	negative selection	4740204
45695910	45695932	5	-	27760321	HT1080	viability	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	1.8417245152272987	[524,409]	[626,711]	8	hSpCas9	negative selection	4740205
45461887	45461909	5	-	27760321	HT29	viability after 7 days	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.7624640291408462	[181,141]	[134,146,88]	-8	hSpCas9	negative selection	4823664
45645261	45645283	5	+	27760321	HT29	viability after 7 days	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.3260126842925559	[553,432]	[947,633,823]	5	hSpCas9	negative selection	4823665
45695743	45695765	5	+	27760321	HT29	viability after 7 days	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.5468097738251102	[531,414]	[1057,688,941]	8	hSpCas9	negative selection	4823666
45695812	45695834	5	+	27760321	HT29	viability after 7 days	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	-0.08520193042067259	[707,552]	[882,711,714]	-1	hSpCas9	negative selection	4823667
45695910	45695932	5	-	27760321	HT29	viability after 7 days	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.8073341090067386	[524,409]	[611,1158,1311]	9	hSpCas9	negative selection	4823668
45461887	45461909	5	-	27760321	HT29	viability after 25 days	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.4803195573242265	[181,141]	[24,209,173]	-4	hSpCas9	negative selection	4907127
45645261	45645283	5	+	27760321	HT29	viability after 25 days	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.37766082403305035	[553,432]	[821,642,725]	4	hSpCas9	negative selection	4907128
45695743	45695765	5	+	27760321	HT29	viability after 25 days	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.3074286119297567	[531,414]	[653,545,824]	3	hSpCas9	negative selection	4907129
45695812	45695834	5	+	27760321	HT29	viability after 25 days	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	-0.13496796003803269	[707,552]	[468,711,814]	-1	hSpCas9	negative selection	4907130
45695910	45695932	5	-	27760321	HT29	viability after 25 days	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.5979127702605564	[524,409]	[812,875,726]	6	hSpCas9	negative selection	4907131
45461887	45461909	5	-	27760321	HT29	viability after 22 days	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.7002727569227427	[181,141]	[145,77,120]	-5	hSpCas9	negative selection	4990590
45645261	45645283	5	+	27760321	HT29	viability after 22 days	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.2571813660208707	[553,432]	[878,515,644]	2	hSpCas9	negative selection	4990591
45695743	45695765	5	+	27760321	HT29	viability after 22 days	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.5305556841154406	[531,414]	[843,687,838]	6	hSpCas9	negative selection	4990592
45695812	45695834	5	+	27760321	HT29	viability after 22 days	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.14010852189078737	[707,552]	[992,674,735]	1	hSpCas9	negative selection	4990593
45695910	45695932	5	-	27760321	HT29	viability after 22 days	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.41488231762235406	[524,409]	[672,760,728]	4	hSpCas9	negative selection	4990594
45461887	45461909	5	-	27760321	HT29	viability after 19 days	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.350002274307444	[181,141]	[160,194,83]	-3	hSpCas9	negative selection	5074053
45645261	45645283	5	+	27760321	HT29	viability after 19 days	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.6008274357435929	[553,432]	[729,931,890]	6	hSpCas9	negative selection	5074054
45695743	45695765	5	+	27760321	HT29	viability after 19 days	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.11589181214150712	[531,414]	[713,382,672]	1	hSpCas9	negative selection	5074055
45695812	45695834	5	+	27760321	HT29	viability after 19 days	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.19728429410153625	[707,552]	[930,900,664]	1	hSpCas9	negative selection	5074056
45695910	45695932	5	-	27760321	HT29	viability after 19 days	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.515223558581539	[524,409]	[941,854,522]	5	hSpCas9	negative selection	5074057
45461887	45461909	5	-	27760321	HT29	viability after 16 days	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.7340262401985811	[181,141]	[109,69,147]	-6	hSpCas9	negative selection	5157516
45645261	45645283	5	+	27760321	HT29	viability after 16 days	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.42500534190028916	[553,432]	[931,814,492]	5	hSpCas9	negative selection	5157517
45695743	45695765	5	+	27760321	HT29	viability after 16 days	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.20106173291238183	[531,414]	[838,589,419]	2	hSpCas9	negative selection	5157518
45695812	45695834	5	+	27760321	HT29	viability after 16 days	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.009146528895139783	[707,552]	[1085,410,675]	0	hSpCas9	negative selection	5157519
45695910	45695932	5	-	27760321	HT29	viability after 16 days	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.35950383781807216	[524,409]	[470,947,567]	4	hSpCas9	negative selection	5157520
45461887	45461909	5	-	27760321	HT29	viability after 13 days	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.4058701986544624	[181,141]	[121,117,182]	-5	hSpCas9	negative selection	5240979
45645261	45645283	5	+	27760321	HT29	viability after 13 days	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.43100424080279454	[553,432]	[1004,809,515]	5	hSpCas9	negative selection	5240980
45695743	45695765	5	+	27760321	HT29	viability after 13 days	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.32372319897926916	[531,414]	[655,797,612]	4	hSpCas9	negative selection	5240981
45695812	45695834	5	+	27760321	HT29	viability after 13 days	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	-0.15964623325420269	[707,552]	[703,633,627]	-2	hSpCas9	negative selection	5240982
45695910	45695932	5	-	27760321	HT29	viability after 13 days	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.19034142404712173	[524,409]	[682,548,623]	2	hSpCas9	negative selection	5240983
45461887	45461909	5	-	27760321	HT29	viability after 10 days	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.37333486727359966	[181,141]	[157,106,200]	-5	hSpCas9	negative selection	5324442
45645261	45645283	5	+	27760321	HT29	viability after 10 days	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.421572476894571	[553,432]	[965,763,745]	6	hSpCas9	negative selection	5324443
45695743	45695765	5	+	27760321	HT29	viability after 10 days	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.5650057095528243	[531,414]	[818,1027,782]	7	hSpCas9	negative selection	5324444
45695812	45695834	5	+	27760321	HT29	viability after 10 days	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.04511322864497458	[707,552]	[1080,598,751]	0	hSpCas9	negative selection	5324445
45695910	45695932	5	-	27760321	HT29	viability after 10 days	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.07813350180733603	[524,409]	[651,689,510]	1	hSpCas9	negative selection	5324446
45461887	45461909	5	-	27760321	MOLM13	viability	TTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-2.606067550259541	[175,181]	[0,29]	-8	hSpCas9	negative selection	5407905
45645261	45645283	5	+	27760321	MOLM13	viability	CTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	0.042021564457505545	[647,553]	[320,370]	0	hSpCas9	negative selection	5407906
45695743	45695765	5	+	27760321	MOLM13	viability	CTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.12591526188247504	[664,531]	[583,180]	0	hSpCas9	negative selection	5407907
45695812	45695834	5	+	27760321	MOLM13	viability	CATGAAGCCGTACTGCCGCCGG	HCN1	ENSG00000164588	0.8298389640879503	[850,707]	[772,782]	6	hSpCas9	negative selection	5407908
45695910	45695932	5	-	27760321	MOLM13	viability	AACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.5459968130371463	[604,524]	[608,340]	4	hSpCas9	negative selection	5407909
45695806	45695829	5	-	27661255	K562	viability	GGCAGTACGGCTTCATGCAGAGG	HCN1	ENSG00000164588	0.15523771627936112	[1416,1500]	[1370,1232]	5	dCas9-KRAB	negative selection	5484218
45695975	45695998	5	-	27661255	K562	viability	GCCGCGGCCGAGAAGCGCCTGGG	HCN1	ENSG00000164588	0.1574519095159057	[275,219]	[250,196]	5	dCas9-KRAB	negative selection	5484219
45461887	45461910	5	-	27260156	BXPC3	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.22347004937319548	[315]	[352,420,304,471]	5	hSpCas9	negative selection	5547112
45353185	45353208	5	+	27260156	BXPC3	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.16866380040059825	[587]	[580,654,620,946]	4	hSpCas9	negative selection	5547113
45396509	45396532	5	+	27260156	BXPC3	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.3538442233201804	[234]	[320,291,323,317]	7	hSpCas9	negative selection	5547114
45645445	45645468	5	+	27260156	BXPC3	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.08019266563966587	[768]	[764,806,864,985]	1	hSpCas9	negative selection	5611373
45396576	45396599	5	+	27260156	BXPC3	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.30054550996089313	[531]	[403,356,463,608]	-6	hSpCas9	negative selection	5611374
45645260	45645283	5	+	27260156	BXPC3	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6325890110484258	[2324]	[1324,1233,1793,2013]	-8	hSpCas9	negative selection	5611375
45461887	45461910	5	-	27260156	A673	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.1064459268876835	[315]	[434,405,334,463]	2	hSpCas9	negative selection	5668363
45353185	45353208	5	+	27260156	A673	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.3911435463028253	[587]	[1014,795,831,1081]	8	hSpCas9	negative selection	5668364
45396509	45396532	5	+	27260156	A673	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.3277985395371583	[234]	[406,377,253,384]	7	hSpCas9	negative selection	5668365
45645445	45645468	5	+	27260156	A673	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.092940319736032	[768]	[1153,974,877,948]	2	hSpCas9	negative selection	5732624
45396576	45396599	5	+	27260156	A673	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.23539256760829147	[531]	[606,513,467,591]	-5	hSpCas9	negative selection	5732625
45645260	45645283	5	+	27260156	A673	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6420037671106713	[2324]	[2136,1682,1647,1724]	-9	hSpCas9	negative selection	5732626
45461887	45461910	5	-	27260156	A375	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.1556923043833522	[315]	[358,618,360,340]	2	hSpCas9	negative selection	5789614
45353185	45353208	5	+	27260156	A375	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.4528702645836043	[587]	[969,925,1068,805]	6	hSpCas9	negative selection	5789615
45396509	45396532	5	+	27260156	A375	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.26816488895003987	[234]	[364,224,436,284]	4	hSpCas9	negative selection	5789616
45645445	45645468	5	+	27260156	A375	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.13496755776257163	[768]	[915,1660,909,594]	2	hSpCas9	negative selection	5853875
45396576	45396599	5	+	27260156	A375	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.11043154845407332	[531]	[672,674,680,316]	-2	hSpCas9	negative selection	5853876
45645260	45645283	5	+	27260156	A375	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.38197836770904714	[2324]	[1853,2129,2188,2150]	-5	hSpCas9	negative selection	5853877
45461887	45461910	5	-	27260156	COLO741	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.12697753654497723	[315]	[416,418,282]	-3	hSpCas9	negative selection	5910865
45353185	45353208	5	+	27260156	COLO741	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.2973238816471016	[587]	[1043,564,1150]	6	hSpCas9	negative selection	5910866
45396509	45396532	5	+	27260156	COLO741	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.36268889201006915	[234]	[514,349,308]	7	hSpCas9	negative selection	5910867
45645445	45645468	5	+	27260156	COLO741	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.09840124530685468	[768]	[939,1066,1130]	2	hSpCas9	negative selection	5975126
45396576	45396599	5	+	27260156	COLO741	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.09228655317671802	[531]	[654,653,847]	2	hSpCas9	negative selection	5975127
45645260	45645283	5	+	27260156	COLO741	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6040191029170987	[2324]	[2289,1854,1756]	-8	hSpCas9	negative selection	5975128
45461887	45461910	5	-	27260156	CAL120	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.15553072218163666	[315]	[364,510,426]	2	hSpCas9	negative selection	6032116
45353185	45353208	5	+	27260156	CAL120	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.3949933322729022	[587]	[1063,911,925]	6	hSpCas9	negative selection	6032117
45396509	45396532	5	+	27260156	CAL120	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	-0.29856504499497416	[234]	[283,189,245]	-4	hSpCas9	negative selection	6032118
45645445	45645468	5	+	27260156	CAL120	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.3348331079486788	[768]	[1135,1010,1457]	5	hSpCas9	negative selection	6096377
45396576	45396599	5	+	27260156	CAL120	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.05629032643253065	[531]	[730,640,698]	0	hSpCas9	negative selection	6096378
45645260	45645283	5	+	27260156	CAL120	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.8231467293989843	[2324]	[1814,1473,1642]	-8	hSpCas9	negative selection	6096379
45461887	45461910	5	-	27260156	CADOES1	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.1642788298897559	[315]	[336,401,338,235]	3	hSpCas9	negative selection	6153367
45353185	45353208	5	+	27260156	CADOES1	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.4605109620915722	[587]	[693,749,792,773]	7	hSpCas9	negative selection	6153368
45396509	45396532	5	+	27260156	CADOES1	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.36919809559800276	[234]	[228,311,341,244]	6	hSpCas9	negative selection	6153369
45645445	45645468	5	+	27260156	CADOES1	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.5343501098381727	[768]	[1002,973,1315,842]	8	hSpCas9	negative selection	6217628
45396576	45396599	5	+	27260156	CADOES1	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.13937993442936356	[531]	[454,494,473,369]	-2	hSpCas9	negative selection	6217629
45645260	45645283	5	+	27260156	CADOES1	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5177494397651097	[2324]	[1365,1396,1498,1789]	-7	hSpCas9	negative selection	6217630
45461887	45461910	5	-	27260156	EWS502	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.23130945455655472	[315]	[369,501,336,355]	4	hSpCas9	negative selection	6274618
45353185	45353208	5	+	27260156	EWS502	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.312264112303729	[587]	[598,878,859,769]	5	hSpCas9	negative selection	6274619
45396509	45396532	5	+	27260156	EWS502	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.24885415512875508	[234]	[245,183,483,279]	4	hSpCas9	negative selection	6274620
45645445	45645468	5	+	27260156	EWS502	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.3015331305784139	[768]	[749,922,1031,1366]	5	hSpCas9	negative selection	6338879
45396576	45396599	5	+	27260156	EWS502	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.020677908902440922	[531]	[515,475,737,495]	0	hSpCas9	negative selection	6338880
45645260	45645283	5	+	27260156	EWS502	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.8202880926699962	[2324]	[1035,1377,1543,1681]	-8	hSpCas9	negative selection	6338881
45461887	45461910	5	-	27260156	EW8	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.23503887900162262	[315]	[379,321,233,288]	4	hSpCas9	negative selection	6395869
45353185	45353208	5	+	27260156	EW8	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.29807682054485024	[587]	[650,584,508,616]	5	hSpCas9	negative selection	6395870
45396509	45396532	5	+	27260156	EW8	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	-0.10259572654228744	[234]	[198,157,172,181]	-2	hSpCas9	negative selection	6395871
45645445	45645468	5	+	27260156	EW8	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.12264555161473167	[768]	[594,642,392,689]	-2	hSpCas9	negative selection	6460130
45396576	45396599	5	+	27260156	EW8	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.3284784127569643	[531]	[421,299,252,420]	-6	hSpCas9	negative selection	6460131
45645260	45645283	5	+	27260156	EW8	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.7740671608226022	[2324]	[1193,1149,902,1200]	-8	hSpCas9	negative selection	6460132
45461887	45461910	5	-	27260156	CORL105	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.16666024955056397	[315]	[538,378,451,301]	3	hSpCas9	negative selection	6517120
45353185	45353208	5	+	27260156	CORL105	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.173451837985638	[587]	[852,622,905,748]	3	hSpCas9	negative selection	6517121
45396509	45396532	5	+	27260156	CORL105	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.15276462755116094	[234]	[377,339,233,261]	3	hSpCas9	negative selection	6517122
45645445	45645468	5	+	27260156	CORL105	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.18253643061439373	[768]	[893,822,1505,938]	3	hSpCas9	negative selection	6581381
45396576	45396599	5	+	27260156	CORL105	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.04753296438945337	[531]	[752,524,671,634]	0	hSpCas9	negative selection	6581382
45645260	45645283	5	+	27260156	CORL105	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5812269187698489	[2324]	[1925,2013,1809,1525]	-8	hSpCas9	negative selection	6581383
45461887	45461910	5	-	27260156	HS294T	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.15473817702424075	[315]	[75,118,109,141]	-2	hSpCas9	negative selection	6638371
45353185	45353208	5	+	27260156	HS294T	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.9616538420988152	[587]	[880,255,274,296]	9	hSpCas9	negative selection	6638372
45396509	45396532	5	+	27260156	HS294T	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	-0.22931170564286707	[234]	[59,64,93,95]	-3	hSpCas9	negative selection	6638373
45645445	45645468	5	+	27260156	HS294T	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.05050375007454222	[768]	[200,291,238,549]	0	hSpCas9	negative selection	6702632
45396576	45396599	5	+	27260156	HS294T	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.06000604160572576	[531]	[170,180,152,385]	0	hSpCas9	negative selection	6702633
45645260	45645283	5	+	27260156	HS294T	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5037510916388799	[2324]	[625,513,578,856]	-6	hSpCas9	negative selection	6702634
45461887	45461910	5	-	27260156	HCC44	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.1652312919429385	[315]	[405,269,624,357]	2	hSpCas9	negative selection	6759622
45353185	45353208	5	+	27260156	HCC44	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.4003490688710662	[587]	[1085,619,1046,836]	6	hSpCas9	negative selection	6759623
45396509	45396532	5	+	27260156	HCC44	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.2825878774382907	[234]	[325,263,191,488]	4	hSpCas9	negative selection	6759624
45645445	45645468	5	+	27260156	HCC44	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.05893984414667075	[768]	[1336,933,700,652]	0	hSpCas9	negative selection	6823883
45396576	45396599	5	+	27260156	HCC44	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.12290738227103022	[531]	[822,483,548,388]	-2	hSpCas9	negative selection	6823884
45645260	45645283	5	+	27260156	HCC44	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6001725679486303	[2324]	[1923,1362,1990,1759]	-7	hSpCas9	negative selection	6823885
45461887	45461910	5	-	27260156	G402	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.06666376591653755	[315]	[271,437,362,517]	0	hSpCas9	negative selection	6880873
45353185	45353208	5	+	27260156	G402	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.6057789077483922	[587]	[1386,844,1078,1080]	7	hSpCas9	negative selection	6880874
45396509	45396532	5	+	27260156	G402	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.052706696943370046	[234]	[321,249,376,242]	0	hSpCas9	negative selection	6880875
45645445	45645468	5	+	27260156	G402	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.3655040458793397	[768]	[1072,1293,1596,868]	4	hSpCas9	negative selection	6945134
45396576	45396599	5	+	27260156	G402	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.36946066224610274	[531]	[453,510,332,693]	-5	hSpCas9	negative selection	6945135
45645260	45645283	5	+	27260156	G402	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.3505967264332672	[2324]	[2067,2024,2628,2138]	-4	hSpCas9	negative selection	6945136
45461887	45461910	5	-	27260156	L33	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.025133954738563058	[315]	[270,137,185,382]	0	hSpCas9	negative selection	7002124
45353185	45353208	5	+	27260156	L33	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.3783251060430684	[587]	[706,322,453,839]	7	hSpCas9	negative selection	7002125
45396509	45396532	5	+	27260156	L33	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.5190315892122432	[234]	[300,140,148,463]	9	hSpCas9	negative selection	7002126
45645445	45645468	5	+	27260156	L33	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.009392128568635916	[768]	[762,311,549,657]	0	hSpCas9	negative selection	7066385
45396576	45396599	5	+	27260156	L33	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.12344314023820091	[531]	[598,227,226,433]	-3	hSpCas9	negative selection	7066386
45645260	45645283	5	+	27260156	L33	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-1.0000036757543822	[2324]	[1145,515,696,1135]	-9	hSpCas9	negative selection	7066387
45461887	45461910	5	-	27260156	K562	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.31715424646784585	[315]	[761,254,276,153]	4	hSpCas9	negative selection	7123375
45353185	45353208	5	+	27260156	K562	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.5669308971644393	[587]	[948,516,476,1106]	7	hSpCas9	negative selection	7123376
45396509	45396532	5	+	27260156	K562	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.10118925562623093	[234]	[205,299,162,226]	1	hSpCas9	negative selection	7123377
45645445	45645468	5	+	27260156	K562	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.5635940688956012	[768]	[917,882,1120,1084]	7	hSpCas9	negative selection	7187636
45396576	45396599	5	+	27260156	K562	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.926809825600188	[531]	[195,174,334,274]	-8	hSpCas9	negative selection	7187637
45645260	45645283	5	+	27260156	K562	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.49812707416497326	[2324]	[1038,1422,2352,1035]	-5	hSpCas9	negative selection	7187638
45461887	45461910	5	-	27260156	HT29	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.4410855023494772	[315]	[493,572,571,453]	8	hSpCas9	negative selection	7244626
45353185	45353208	5	+	27260156	HT29	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.39444669782278435	[587]	[1084,951,898,839]	7	hSpCas9	negative selection	7244627
45396509	45396532	5	+	27260156	HT29	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.16675692638508655	[234]	[423,292,266,303]	3	hSpCas9	negative selection	7244628
45645445	45645468	5	+	27260156	HT29	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.29993767089361767	[768]	[1323,1114,1318,880]	6	hSpCas9	negative selection	7308887
45396576	45396599	5	+	27260156	HT29	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.24592743062200523	[531]	[525,548,481,610]	-5	hSpCas9	negative selection	7308888
45645260	45645283	5	+	27260156	HT29	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.47225458645792373	[2324]	[2353,2566,1594,1726]	-7	hSpCas9	negative selection	7308889
45461887	45461910	5	-	27260156	MHHES1	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.16840658534482028	[315]	[475,335,405,379]	3	hSpCas9	negative selection	7365877
45353185	45353208	5	+	27260156	MHHES1	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.30570055075140407	[587]	[866,904,977,577]	5	hSpCas9	negative selection	7365878
45396509	45396532	5	+	27260156	MHHES1	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.19707627787718085	[234]	[285,533,226,203]	3	hSpCas9	negative selection	7365879
45645445	45645468	5	+	27260156	MHHES1	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.17092604744096984	[768]	[1352,893,1100,645]	3	hSpCas9	negative selection	7430138
45396576	45396599	5	+	27260156	MHHES1	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.3160914212700161	[531]	[447,486,607,389]	-5	hSpCas9	negative selection	7430139
45645260	45645283	5	+	27260156	MHHES1	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5631282184396704	[2324]	[2027,1930,2042,1224]	-8	hSpCas9	negative selection	7430140
45461887	45461910	5	-	27260156	MEWO	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.23359247094002722	[315]	[466,316,281]	5	hSpCas9	negative selection	7487128
45353185	45353208	5	+	27260156	MEWO	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.27026273115245875	[587]	[736,549,717]	6	hSpCas9	negative selection	7487129
45396509	45396532	5	+	27260156	MEWO	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.15742342638179407	[234]	[237,278,216]	3	hSpCas9	negative selection	7487130
45645445	45645468	5	+	27260156	MEWO	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.03340326965401974	[768]	[860,579,698]	0	hSpCas9	negative selection	7551389
45396576	45396599	5	+	27260156	MEWO	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.010810185626233731	[531]	[805,352,404]	0	hSpCas9	negative selection	7551390
45645260	45645283	5	+	27260156	MEWO	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.7351471080227581	[2324]	[1412,1420,1105]	-9	hSpCas9	negative selection	7551391
45461887	45461910	5	-	27260156	LNCAPCLONEFGC	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.4029402997008708	[315]	[440,361,293,403]	6	hSpCas9	negative selection	7608379
45353185	45353208	5	+	27260156	LNCAPCLONEFGC	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.4256545366709959	[587]	[691,662,693,812]	6	hSpCas9	negative selection	7608380
45396509	45396532	5	+	27260156	LNCAPCLONEFGC	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.41399027266870725	[234]	[286,233,279,335]	6	hSpCas9	negative selection	7608381
45645445	45645468	5	+	27260156	LNCAPCLONEFGC	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.32596462492983624	[768]	[898,732,1068,828]	5	hSpCas9	negative selection	7672640
45396576	45396599	5	+	27260156	LNCAPCLONEFGC	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.08222985377846367	[531]	[510,442,540,337]	-1	hSpCas9	negative selection	7672641
45645260	45645283	5	+	27260156	LNCAPCLONEFGC	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6494281643088573	[2324]	[1476,1222,1340,1333]	-7	hSpCas9	negative selection	7672642
45461887	45461910	5	-	27260156	PANC0327	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.6290540511301462	[315]	[457,343,472,474]	8	hSpCas9	negative selection	7729630
45353185	45353208	5	+	27260156	PANC0327	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.6568454579312162	[587]	[886,1046,666,668]	8	hSpCas9	negative selection	7729631
45396509	45396532	5	+	27260156	PANC0327	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.12686561753434167	[234]	[144,210,220,329]	1	hSpCas9	negative selection	7729632
45645445	45645468	5	+	27260156	PANC0327	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.3500992431301426	[768]	[937,753,798,1011]	5	hSpCas9	negative selection	7793891
45396576	45396599	5	+	27260156	PANC0327	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.31743413702180323	[531]	[207,546,301,423]	-5	hSpCas9	negative selection	7793892
45645260	45645283	5	+	27260156	PANC0327	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.09392277295395024	[2324]	[2573,1621,1955,1680]	-1	hSpCas9	negative selection	7793893
45461887	45461910	5	-	27260156	NCIH2009	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.21527543793611537	[315]	[419,330,397]	-3	hSpCas9	negative selection	7850881
45353185	45353208	5	+	27260156	NCIH2009	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.13013556233897539	[587]	[708,1181,761]	1	hSpCas9	negative selection	7850882
45396509	45396532	5	+	27260156	NCIH2009	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.029532455857834483	[234]	[517,276,246]	0	hSpCas9	negative selection	7850883
45645445	45645468	5	+	27260156	NCIH2009	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.5466879073490767	[768]	[1796,1436,1518]	7	hSpCas9	negative selection	7915142
45396576	45396599	5	+	27260156	NCIH2009	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.1767934561928587	[531]	[1371,633,621]	2	hSpCas9	negative selection	7915143
45645260	45645283	5	+	27260156	NCIH2009	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.8188099481144218	[2324]	[2377,1815,1433]	-7	hSpCas9	negative selection	7915144
45461887	45461910	5	-	27260156	NCIH1373	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.48030879756250416	[315]	[573,511,471,110]	5	hSpCas9	negative selection	7972132
45353185	45353208	5	+	27260156	NCIH1373	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.563308288100004	[587]	[918,829,1085,279]	5	hSpCas9	negative selection	7972133
45396509	45396532	5	+	27260156	NCIH1373	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	-0.11639867169260976	[234]	[84,163,453,64]	-1	hSpCas9	negative selection	7972134
45645445	45645468	5	+	27260156	NCIH1373	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.7859939261387539	[768]	[1358,1295,1539,461]	7	hSpCas9	negative selection	8036393
45396576	45396599	5	+	27260156	NCIH1373	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.04282500195952027	[531]	[543,512,636,201]	0	hSpCas9	negative selection	8036394
45645260	45645283	5	+	27260156	NCIH1373	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.9038961683279558	[2324]	[1170,1511,1452,361]	-7	hSpCas9	negative selection	8036395
45461887	45461910	5	-	27260156	PATU8902	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.39229928207490855	[315]	[534,869,370,585]	4	hSpCas9	negative selection	8093383
45353185	45353208	5	+	27260156	PATU8902	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.7929582061793294	[587]	[1494,1667,1165,1397]	8	hSpCas9	negative selection	8093384
45396509	45396532	5	+	27260156	PATU8902	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.442800555378847	[234]	[439,304,378,698]	4	hSpCas9	negative selection	8093385
45645445	45645468	5	+	27260156	PATU8902	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.1262429995765797	[768]	[897,1366,926,1591]	1	hSpCas9	negative selection	8157644
45396576	45396599	5	+	27260156	PATU8902	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.14638553807083454	[531]	[408,797,737,1427]	1	hSpCas9	negative selection	8157645
45645260	45645283	5	+	27260156	PATU8902	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5471100250570824	[2324]	[2762,1980,1778,2457]	-5	hSpCas9	negative selection	8157646
45461887	45461910	5	-	27260156	PANC1	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.29207068462788827	[315]	[332,426,286,300]	5	hSpCas9	negative selection	8214634
45353185	45353208	5	+	27260156	PANC1	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.4039233073082515	[587]	[449,927,654,683]	6	hSpCas9	negative selection	8214635
45396509	45396532	5	+	27260156	PANC1	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.7355233874645708	[234]	[296,578,287,240]	9	hSpCas9	negative selection	8214636
45645445	45645468	5	+	27260156	PANC1	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.020987008670750762	[768]	[778,558,748,573]	0	hSpCas9	negative selection	8278895
45396576	45396599	5	+	27260156	PANC1	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.078922758314656	[531]	[301,596,541,335]	-1	hSpCas9	negative selection	8278896
45645260	45645283	5	+	27260156	PANC1	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6042079356275958	[2324]	[1348,1663,1080,1222]	-7	hSpCas9	negative selection	8278897
45461887	45461910	5	-	27260156	PANC0813	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.10970577270092674	[315]	[434,306,371,273]	-2	hSpCas9	negative selection	8335885
45353185	45353208	5	+	27260156	PANC0813	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.24817749071593637	[587]	[884,820,850,733]	4	hSpCas9	negative selection	8335886
45396509	45396532	5	+	27260156	PANC0813	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.3650008202316021	[234]	[333,328,457,301]	6	hSpCas9	negative selection	8335887
45645445	45645468	5	+	27260156	PANC0813	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.17185147290722125	[768]	[957,926,1026,1143]	3	hSpCas9	negative selection	8400146
45396576	45396599	5	+	27260156	PANC0813	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.05365978327533827	[531]	[525,515,788,571]	-1	hSpCas9	negative selection	8400147
45645260	45645283	5	+	27260156	PANC0813	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.7517568329641098	[2324]	[1826,1525,1639,1516]	-8	hSpCas9	negative selection	8400148
45461887	45461910	5	-	27260156	RDES	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.4571942605610981	[315]	[429,360,562,685]	7	hSpCas9	negative selection	8457136
45353185	45353208	5	+	27260156	RDES	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.30769717598176344	[587]	[707,633,1023,1042]	5	hSpCas9	negative selection	8457137
45396509	45396532	5	+	27260156	RDES	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.30560298305169653	[234]	[308,219,424,401]	5	hSpCas9	negative selection	8457138
45645445	45645468	5	+	27260156	RDES	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.251695509769841	[768]	[849,940,1177,1309]	4	hSpCas9	negative selection	8521397
45396576	45396599	5	+	27260156	RDES	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.0483248295444384	[531]	[465,601,614,710]	-1	hSpCas9	negative selection	8521398
45645260	45645283	5	+	27260156	RDES	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6236118200940417	[2324]	[1411,1580,1928,2117]	-8	hSpCas9	negative selection	8521399
45461887	45461910	5	-	27260156	PC3	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.47905817443261595	[315]	[299,392,723,468]	8	hSpCas9	negative selection	8578387
45353185	45353208	5	+	27260156	PC3	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.3097969141513291	[587]	[524,542,1102,908]	6	hSpCas9	negative selection	8578388
45396509	45396532	5	+	27260156	PC3	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.24391529303332948	[234]	[135,340,421,303]	5	hSpCas9	negative selection	8578389
45645445	45645468	5	+	27260156	PC3	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.10061423202736719	[768]	[541,879,1327,766]	2	hSpCas9	negative selection	8642648
45396576	45396599	5	+	27260156	PC3	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.17226780971302197	[531]	[316,395,716,575]	-4	hSpCas9	negative selection	8642649
45645260	45645283	5	+	27260156	PC3	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.8345130989727558	[2324]	[950,1049,2041,1474]	-9	hSpCas9	negative selection	8642650
45461887	45461910	5	-	27260156	PATU8988T	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.485950482032887	[315]	[153,530,435,613]	7	hSpCas9	negative selection	8699638
45353185	45353208	5	+	27260156	PATU8988T	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.17597245722536353	[587]	[653,770,536,616]	3	hSpCas9	negative selection	8699639
45396509	45396532	5	+	27260156	PATU8988T	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	-0.5310128899787068	[234]	[197,106,120,201]	-7	hSpCas9	negative selection	8699640
45645445	45645468	5	+	27260156	PATU8988T	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.16097447246863206	[768]	[736,779,981,815]	2	hSpCas9	negative selection	8763899
45396576	45396599	5	+	27260156	PATU8988T	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.30916411326949855	[531]	[247,401,550,458]	-5	hSpCas9	negative selection	8763900
45645260	45645283	5	+	27260156	PATU8988T	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5702972868477356	[2324]	[1192,1661,1444,1788]	-7	hSpCas9	negative selection	8763901
45461887	45461910	5	-	27260156	T47D	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.2072501487432074	[315]	[425,492,312,464]	4	hSpCas9	negative selection	8820889
45353185	45353208	5	+	27260156	T47D	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.38509942856099405	[587]	[798,866,958,955]	7	hSpCas9	negative selection	8820890
45396509	45396532	5	+	27260156	T47D	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.18347384146854573	[234]	[344,316,305,273]	4	hSpCas9	negative selection	8820891
45645445	45645468	5	+	27260156	T47D	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.19198185723889072	[768]	[917,1053,1031,1087]	4	hSpCas9	negative selection	8885150
45396576	45396599	5	+	27260156	T47D	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.24683512179845368	[531]	[475,533,520,557]	-5	hSpCas9	negative selection	8885151
45645260	45645283	5	+	27260156	T47D	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5816119481620556	[2324]	[1712,1580,1951,2016]	-8	hSpCas9	negative selection	8885152
45461887	45461910	5	-	27260156	SU8686	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.07468549312802564	[315]	[376,258,267,431]	1	hSpCas9	negative selection	8942140
45353185	45353208	5	+	27260156	SU8686	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.10179225054854596	[587]	[536,666,609,699]	1	hSpCas9	negative selection	8942141
45396509	45396532	5	+	27260156	SU8686	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.23542131301859148	[234]	[234,249,237,398]	4	hSpCas9	negative selection	8942142
45645445	45645468	5	+	27260156	SU8686	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.24399784811277914	[768]	[780,846,954,1071]	4	hSpCas9	negative selection	9006401
45396576	45396599	5	+	27260156	SU8686	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	0.16303579124788625	[531]	[586,533,632,616]	2	hSpCas9	negative selection	9006402
45645260	45645283	5	+	27260156	SU8686	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.6951092932186014	[2324]	[1255,1269,1675,1548]	-7	hSpCas9	negative selection	9006403
45461887	45461910	5	-	27260156	SKES1	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.012506524260453178	[315]	[354,314,224,353]	0	hSpCas9	negative selection	9063391
45353185	45353208	5	+	27260156	SKES1	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.2997153779410329	[587]	[780,701,758,651]	6	hSpCas9	negative selection	9063392
45396509	45396532	5	+	27260156	SKES1	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.211431666637952	[234]	[194,311,290,277]	4	hSpCas9	negative selection	9063393
45645445	45645468	5	+	27260156	SKES1	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.04700805728703039	[768]	[834,929,719,709]	1	hSpCas9	negative selection	9127652
45396576	45396599	5	+	27260156	SKES1	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.3737691363166431	[531]	[587,434,427,231]	-7	hSpCas9	negative selection	9127653
45645260	45645283	5	+	27260156	SKES1	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.667236856911195	[2324]	[1767,1767,1412,1011]	-9	hSpCas9	negative selection	9127654
45461887	45461910	5	-	27260156	TOV112D	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	-0.10363000845829717	[315]	[213,192,409,327]	-2	hSpCas9	negative selection	9184642
45353185	45353208	5	+	27260156	TOV112D	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.2880320894076909	[587]	[605,997,642,687]	5	hSpCas9	negative selection	9184643
45396509	45396532	5	+	27260156	TOV112D	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.054504421386431634	[234]	[232,308,269,181]	1	hSpCas9	negative selection	9184644
45645445	45645468	5	+	27260156	TOV112D	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	-0.003913274368414488	[768]	[934,958,535,703]	0	hSpCas9	negative selection	9248903
45396576	45396599	5	+	27260156	TOV112D	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.18430322481186234	[531]	[597,351,364,539]	-4	hSpCas9	negative selection	9248904
45645260	45645283	5	+	27260156	TOV112D	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5692400455329518	[2324]	[1498,1578,1932,1268]	-8	hSpCas9	negative selection	9248905
45461887	45461910	5	-	27260156	TC71	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.002151648768727643	[315]	[305,360,323,368]	0	hSpCas9	negative selection	9305893
45353185	45353208	5	+	27260156	TC71	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.39413179571253937	[587]	[793,724,1056,723]	8	hSpCas9	negative selection	9305894
45396509	45396532	5	+	27260156	TC71	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	0.11576636891687286	[234]	[238,229,328,293]	3	hSpCas9	negative selection	9305895
45645445	45645468	5	+	27260156	TC71	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.15241299182084267	[768]	[897,943,790,1043]	4	hSpCas9	negative selection	9370154
45396576	45396599	5	+	27260156	TC71	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.22160760491888076	[531]	[427,423,607,493]	-5	hSpCas9	negative selection	9370155
45645260	45645283	5	+	27260156	TC71	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.5698848824960037	[2324]	[1631,1763,1850,1449]	-9	hSpCas9	negative selection	9370156
45461887	45461910	5	-	27260156	TC32	viability	GTTCTTAGTACCACTACTGCAGG	HCN1	ENSG00000164588	0.31676106542914045	[315]	[289,355,436,401]	5	hSpCas9	negative selection	9427144
45353185	45353208	5	+	27260156	TC32	viability	ATCTTCTGACGCATATCAGCTGG	HCN1	ENSG00000164588	0.4881081928006961	[587]	[786,499,1089,838]	8	hSpCas9	negative selection	9427145
45396509	45396532	5	+	27260156	TC32	viability	GCCTCGAAGAATCCAGAGACTGG	HCN1	ENSG00000164588	-0.043511659593497454	[234]	[142,183,361,200]	0	hSpCas9	negative selection	9427146
45645445	45645468	5	+	27260156	TC32	viability	CAGTCCTAAAATTCATGATCAGG	HCN1	ENSG00000164588	0.1886599475343197	[768]	[673,701,1227,772]	3	hSpCas9	negative selection	9491405
45396576	45396599	5	+	27260156	TC32	viability	CCCGACGATCATGCTCAGCATGG	HCN1	ENSG00000164588	-0.1343767958001098	[531]	[366,379,640,479]	-2	hSpCas9	negative selection	9491406
45645260	45645283	5	+	27260156	TC32	viability	CCTCACAATGCGAAGTGCCCTGG	HCN1	ENSG00000164588	-0.4011598396206246	[2324]	[1751,1209,2040,1741]	-6	hSpCas9	negative selection	9491407
45303692	45303715	5	-	27869803	HPAFII	viability after 27 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.083667397000881	[198]	[35,150,NaN]	0	hSpCas9	negative selection	9592025
45353099	45353122	5	-	27869803	HPAFII	viability after 27 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	1.0225769683114505	[190]	[197,208,NaN]	8	hSpCas9	negative selection	9592026
45396527	45396550	5	+	27869803	HPAFII	viability after 27 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	1.4267289083584251	[105]	[175,127,NaN]	9	hSpCas9	negative selection	9592028
45461908	45461931	5	+	27869803	HPAFII	viability after 27 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	1.2407383396353338	[173]	[315,132,NaN]	8	hSpCas9	negative selection	9592029
45645337	45645360	5	-	27869803	HPAFII	viability after 27 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-1.2509754456676128	[220]	[50,46,NaN]	-7	hSpCas9	negative selection	9592030
45696052	45696075	5	-	27869803	HPAFII	viability after 27 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.916356558428421	[304]	[414,208,NaN]	7	hSpCas9	negative selection	9592031
45303692	45303715	5	-	27869803	HPAFII	viability after 15 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.1756498375653684	[198]	[190,272,NaN]	2	hSpCas9	negative selection	9674474
45353099	45353122	5	-	27869803	HPAFII	viability after 15 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.2543190021303342	[190]	[361,171,NaN]	3	hSpCas9	negative selection	9674475
45396527	45396550	5	+	27869803	HPAFII	viability after 15 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	1.2673647745940742	[105]	[272,274,NaN]	9	hSpCas9	negative selection	9674477
45461908	45461931	5	+	27869803	HPAFII	viability after 15 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.4159271440451237	[173]	[505,89,NaN]	5	hSpCas9	negative selection	9674478
45645337	45645360	5	-	27869803	HPAFII	viability after 15 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.06169481336273114	[220]	[287,189,NaN]	0	hSpCas9	negative selection	9674479
45696052	45696075	5	-	27869803	HPAFII	viability after 15 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.6973293262624511	[304]	[697,427,NaN]	7	hSpCas9	negative selection	9674480
45303692	45303715	5	-	27869803	ASPC1	viability after 36 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.08770578637629643	[623]	[266,125,221]	-1	hSpCas9	negative selection	9756923
45353099	45353122	5	-	27869803	ASPC1	viability after 36 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.813976986175615	[606]	[286,308,478]	7	hSpCas9	negative selection	9756924
45396527	45396550	5	+	27869803	ASPC1	viability after 36 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.6206383536537576	[474]	[118,50,143]	-6	hSpCas9	negative selection	9756926
45461908	45461931	5	+	27869803	ASPC1	viability after 36 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	0.42902500352696077	[434]	[104,400,115]	4	hSpCas9	negative selection	9756927
45645337	45645360	5	-	27869803	ASPC1	viability after 36 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.08250939820301051	[786]	[231,431,138]	-1	hSpCas9	negative selection	9756928
45696052	45696075	5	-	27869803	ASPC1	viability after 36 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.30278054840919266	[937]	[364,428,406]	3	hSpCas9	negative selection	9756929
45303692	45303715	5	-	27869803	PATU8988S	viability after 35 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.05420154384153847	[440]	[198,142,NaN]	0	hSpCas9	negative selection	9839372
45353099	45353122	5	-	27869803	PATU8988S	viability after 35 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.8220999139128234	[557]	[539,253,NaN]	8	hSpCas9	negative selection	9839373
45396527	45396550	5	+	27869803	PATU8988S	viability after 35 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	-0.14396646931571422	[386]	[167,113,NaN]	-1	hSpCas9	negative selection	9839375
45461908	45461931	5	+	27869803	PATU8988S	viability after 35 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	1.3001305542960668	[445]	[368,515,NaN]	9	hSpCas9	negative selection	9839376
45645337	45645360	5	-	27869803	PATU8988S	viability after 35 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.01977217626459016	[529]	[173,258,NaN]	0	hSpCas9	negative selection	9839377
45696052	45696075	5	-	27869803	PATU8988S	viability after 35 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.6654379211074263	[808]	[417,615,NaN]	7	hSpCas9	negative selection	9839378
45303692	45303715	5	-	27869803	PATU8988S	viability after 31 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	0.03372179084565663	[440]	[201,151,NaN]	0	hSpCas9	negative selection	9921821
45353099	45353122	5	-	27869803	PATU8988S	viability after 31 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.6913336422561018	[557]	[386,323,NaN]	7	hSpCas9	negative selection	9921822
45396527	45396550	5	+	27869803	PATU8988S	viability after 31 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.35966709962622656	[386]	[219,169,NaN]	4	hSpCas9	negative selection	9921824
45461908	45461931	5	+	27869803	PATU8988S	viability after 31 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	1.1115176945854346	[445]	[301,488,NaN]	9	hSpCas9	negative selection	9921825
45645337	45645360	5	-	27869803	PATU8988S	viability after 31 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	0.12453887267327148	[529]	[170,305,NaN]	1	hSpCas9	negative selection	9921826
45696052	45696075	5	-	27869803	PATU8988S	viability after 31 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	0.32438314065428075	[808]	[384,427,NaN]	4	hSpCas9	negative selection	9921827
45303692	45303715	5	-	27869803	HPAFII	viability after 35 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-1.1917388061932077	[198]	[13,77,NaN]	-6	hSpCas9	negative selection	10004270
45353099	45353122	5	-	27869803	HPAFII	viability after 35 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	1.3192989291816137	[190]	[237,244,NaN]	8	hSpCas9	negative selection	10004271
45396527	45396550	5	+	27869803	HPAFII	viability after 35 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	0.7998117679851775	[105]	[107,76,NaN]	5	hSpCas9	negative selection	10004273
45461908	45461931	5	+	27869803	HPAFII	viability after 35 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	1.1778027519704555	[173]	[290,95,NaN]	7	hSpCas9	negative selection	10004274
45645337	45645360	5	-	27869803	HPAFII	viability after 35 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.5965147666182997	[220]	[57,91,NaN]	-4	hSpCas9	negative selection	10004275
45696052	45696075	5	-	27869803	HPAFII	viability after 35 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	1.3460809223498282	[304]	[511,257,NaN]	8	hSpCas9	negative selection	10004276
45303692	45303715	5	-	27869803	HPAFII	viability after 31 days	TATCATACGAGAAGGAGCCGTGG	HCN1	ENSG00000164588	-0.44268847737405964	[198]	[85,77,NaN]	-3	hSpCas9	negative selection	10086719
45353099	45353122	5	-	27869803	HPAFII	viability after 31 days	ACTCAATGATCCTCTGAGAGAGG	HCN1	ENSG00000164588	0.7543642184917161	[190]	[187,172,NaN]	5	hSpCas9	negative selection	10086720
45396527	45396550	5	+	27869803	HPAFII	viability after 31 days	ACTGGATTAAAGCGGTGGCATGG	HCN1	ENSG00000164588	1.013371469319066	[105]	[121,117,NaN]	7	hSpCas9	negative selection	10086722
45461908	45461931	5	+	27869803	HPAFII	viability after 31 days	ACTGAAGACAACCATCCCAGTGG	HCN1	ENSG00000164588	1.0397865423444483	[173]	[295,96,NaN]	7	hSpCas9	negative selection	10086723
45645337	45645360	5	-	27869803	HPAFII	viability after 31 days	CTTCATCTCATCCATCCCAGTGG	HCN1	ENSG00000164588	-0.6987608883149894	[220]	[40,114,NaN]	-4	hSpCas9	negative selection	10086724
45696052	45696075	5	-	27869803	HPAFII	viability after 31 days	CCAACTCTTCGTCTAACAGCCGG	HCN1	ENSG00000164588	1.439863358128708	[304]	[617,296,NaN]	9	hSpCas9	negative selection	10086725
45695742	45695765	5	+	28162770	P31FUJ	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	3.430162808308051	[5]	[75]	9	hSpCas9	negative selection	10167789
45695910	45695933	5	-	28162770	P31FUJ	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.1609875611604259	[512]	[673]	1	hSpCas9	negative selection	10167790
45461859	45461882	5	+	28162770	P31FUJ	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.9110335681592729	[61]	[136]	9	hSpCas9	negative selection	10167791
45695894	45695917	5	-	28162770	P31FUJ	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	1.3521602963067778	[13]	[41]	9	hSpCas9	negative selection	10167792
45695721	45695744	5	-	28162770	P31FUJ	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.6812627052306728	[130]	[47]	-8	hSpCas9	negative selection	10167793
45396606	45396629	5	+	28162770	P31FUJ	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.22662941422291855	[199]	[274]	2	hSpCas9	negative selection	10167794
45396552	45396575	5	+	28162770	P31FUJ	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.6003787050111307	[260]	[464]	7	hSpCas9	negative selection	10167795
45396522	45396545	5	+	28162770	P31FUJ	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	0.46867430503320273	[106]	[173]	5	hSpCas9	negative selection	10167796
45396491	45396514	5	-	28162770	P31FUJ	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.27831126641951265	[333]	[475]	3	hSpCas9	negative selection	10167797
45695929	45695952	5	+	28162770	P31FUJ	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.6434624271633766	[364]	[669]	7	hSpCas9	negative selection	10167798
45695742	45695765	5	+	28162770	TF1	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10337155
45695910	45695933	5	-	28162770	TF1	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10337156
45461859	45461882	5	+	28162770	TF1	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10337157
45695894	45695917	5	-	28162770	TF1	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10337158
45695721	45695744	5	-	28162770	TF1	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10337159
45396606	45396629	5	+	28162770	TF1	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10337160
45396552	45396575	5	+	28162770	TF1	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	NaN	[NaN]	[247]	1	hSpCas9	negative selection	10337161
45396522	45396545	5	+	28162770	TF1	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10337162
45396491	45396514	5	-	28162770	TF1	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	NaN	[NaN]	[394]	1	hSpCas9	negative selection	10337163
45695929	45695952	5	+	28162770	TF1	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10337164
45695742	45695765	5	+	28162770	SKM1	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10506521
45695910	45695933	5	-	28162770	SKM1	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.6283112760043688	[100]	[275]	6	hSpCas9	negative selection	10506522
45461859	45461882	5	+	28162770	SKM1	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	-0.2814333166593026	[21]	[31]	-2	hSpCas9	negative selection	10506523
45695894	45695917	5	-	28162770	SKM1	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10506524
45695721	45695744	5	-	28162770	SKM1	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.1439297929093677	[54]	[43]	-7	hSpCas9	negative selection	10506525
45396606	45396629	5	+	28162770	SKM1	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.7629608026991506	[57]	[173]	7	hSpCas9	negative selection	10506526
45396552	45396575	5	+	28162770	SKM1	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.5259216053983014	[76]	[195]	5	hSpCas9	negative selection	10506527
45396522	45396545	5	+	28162770	SKM1	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-0.15903668529957615	[23]	[37]	-1	hSpCas9	negative selection	10506528
45396491	45396514	5	-	28162770	SKM1	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	-0.08828176335945337	[88]	[147]	0	hSpCas9	negative selection	10506529
45695929	45695952	5	+	28162770	SKM1	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.987667089873845	[88]	[311]	8	hSpCas9	negative selection	10506530
45695742	45695765	5	+	28162770	SKM1	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10675887
45695910	45695933	5	-	28162770	SKM1	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.6283112760043688	[100]	[275]	6	hSpCas9	negative selection	10675888
45461859	45461882	5	+	28162770	SKM1	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	-0.2814333166593026	[21]	[31]	-2	hSpCas9	negative selection	10675889
45695894	45695917	5	-	28162770	SKM1	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10675890
45695721	45695744	5	-	28162770	SKM1	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.1439297929093677	[54]	[43]	-7	hSpCas9	negative selection	10675891
45396606	45396629	5	+	28162770	SKM1	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.7629608026991506	[57]	[173]	7	hSpCas9	negative selection	10675892
45396552	45396575	5	+	28162770	SKM1	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.5259216053983014	[76]	[195]	5	hSpCas9	negative selection	10675893
45396522	45396545	5	+	28162770	SKM1	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-0.15903668529957615	[23]	[37]	-1	hSpCas9	negative selection	10675894
45396491	45396514	5	-	28162770	SKM1	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	-0.08828176335945337	[88]	[147]	0	hSpCas9	negative selection	10675895
45695929	45695952	5	+	28162770	SKM1	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.987667089873845	[88]	[311]	8	hSpCas9	negative selection	10675896
45695742	45695765	5	+	28162770	PL21	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	1.6151771137681643	[11]	[15]	9	hSpCas9	negative selection	10845253
45695910	45695933	5	-	28162770	PL21	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.05863693352609167	[288]	[130]	0	hSpCas9	negative selection	10845254
45461859	45461882	5	+	28162770	PL21	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	1.516167107936998	[48]	[60]	9	hSpCas9	negative selection	10845255
45695894	45695917	5	-	28162770	PL21	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	1.20013961448932	[23]	[23]	8	hSpCas9	negative selection	10845256
45695721	45695744	5	-	28162770	PL21	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-0.7703161098966647	[144]	[36]	-5	hSpCas9	negative selection	10845257
45396606	45396629	5	+	28162770	PL21	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.18128058723800428	[230]	[113]	1	hSpCas9	negative selection	10845258
45396552	45396575	5	+	28162770	PL21	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	-0.7290873110972989	[178]	[46]	-5	hSpCas9	negative selection	10845259
45396522	45396545	5	+	28162770	PL21	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-0.06734069637566553	[64]	[26]	0	hSpCas9	negative selection	10845260
45396491	45396514	5	-	28162770	PL21	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.6563158085616504	[241]	[165]	5	hSpCas9	negative selection	10845261
45695929	45695952	5	+	28162770	PL21	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.4020032224610949	[272]	[156]	3	hSpCas9	negative selection	10845262
45695742	45695765	5	+	28162770	P31FUJ	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	3.430162808308051	[5]	[75]	9	hSpCas9	negative selection	11014619
45695910	45695933	5	-	28162770	P31FUJ	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.1609875611604259	[512]	[673]	1	hSpCas9	negative selection	11014620
45461859	45461882	5	+	28162770	P31FUJ	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.9110335681592729	[61]	[136]	9	hSpCas9	negative selection	11014621
45695894	45695917	5	-	28162770	P31FUJ	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	1.3521602963067778	[13]	[41]	9	hSpCas9	negative selection	11014622
45695721	45695744	5	-	28162770	P31FUJ	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.6812627052306728	[130]	[47]	-8	hSpCas9	negative selection	11014623
45396606	45396629	5	+	28162770	P31FUJ	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.22662941422291855	[199]	[274]	2	hSpCas9	negative selection	11014624
45396552	45396575	5	+	28162770	P31FUJ	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.6003787050111307	[260]	[464]	7	hSpCas9	negative selection	11014625
45396522	45396545	5	+	28162770	P31FUJ	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	0.46867430503320273	[106]	[173]	5	hSpCas9	negative selection	11014626
45396491	45396514	5	-	28162770	P31FUJ	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.27831126641951265	[333]	[475]	3	hSpCas9	negative selection	11014627
45695929	45695952	5	+	28162770	P31FUJ	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.6434624271633766	[364]	[669]	7	hSpCas9	negative selection	11014628
45695742	45695765	5	+	28162770	OCIAML5	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.1937371187491277	[30]	[63]	1	hSpCas9	negative selection	11183985
45695910	45695933	5	-	28162770	OCIAML5	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.5171672388017221	[275]	[712]	4	hSpCas9	negative selection	11183986
45461859	45461882	5	+	28162770	OCIAML5	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.9702905145328539	[40]	[144]	8	hSpCas9	negative selection	11183987
45695894	45695917	5	-	28162770	OCIAML5	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	0.437440046330988	[8]	[21]	4	hSpCas9	negative selection	11183988
45695721	45695744	5	-	28162770	OCIAML5	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.0915325055593863	[84]	[71]	-6	hSpCas9	negative selection	11183989
45396606	45396629	5	+	28162770	OCIAML5	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.418260327536153	[147]	[356]	3	hSpCas9	negative selection	11183990
45396552	45396575	5	+	28162770	OCIAML5	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	1.2911556370388433	[102]	[454]	9	hSpCas9	negative selection	11183991
45396522	45396545	5	+	28162770	OCIAML5	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	0.2150476249945401	[41]	[87]	1	hSpCas9	negative selection	11183992
45396491	45396514	5	-	28162770	OCIAML5	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	1.0340138374224324	[134]	[498]	8	hSpCas9	negative selection	11183993
45695929	45695952	5	+	28162770	OCIAML5	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	-0.21236110554840865	[180]	[281]	-1	hSpCas9	negative selection	11183994
45695742	45695765	5	+	28162770	EOL1	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.9735726144102519	[40]	[10]	-6	hSpCas9	negative selection	11353351
45695910	45695933	5	-	28162770	EOL1	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.6712323704721926	[502]	[421]	6	hSpCas9	negative selection	11353352
45461859	45461882	5	+	28162770	EOL1	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	-1.3758471617671866	[132]	[26]	-7	hSpCas9	negative selection	11353353
45695894	45695917	5	-	28162770	EOL1	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	1.5766244681502277	[27]	[43]	9	hSpCas9	negative selection	11353354
45695721	45695744	5	-	28162770	EOL1	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-2.723424526676422	[350]	[27]	-9	hSpCas9	negative selection	11353355
45396606	45396629	5	+	28162770	EOL1	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	1.2844437166569174	[419]	[538]	9	hSpCas9	negative selection	11353356
45396552	45396575	5	+	28162770	EOL1	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.09055772300946374	[245]	[137]	0	hSpCas9	negative selection	11353357
45396522	45396545	5	+	28162770	EOL1	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-1.2926829446501347	[92]	[19]	-7	hSpCas9	negative selection	11353358
45396491	45396514	5	-	28162770	EOL1	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.20125711430140492	[349]	[211]	1	hSpCas9	negative selection	11353359
45695929	45695952	5	+	28162770	EOL1	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.1561734726850194	[355]	[208]	1	hSpCas9	negative selection	11353360
45695742	45695765	5	+	28162770	MOLM13	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.3303858577946439	[21]	[19]	2	hSpCas9	negative selection	11522717
45695910	45695933	5	-	28162770	MOLM13	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	-0.0786777404395671	[481]	[329]	0	hSpCas9	negative selection	11522718
45461859	45461882	5	+	28162770	MOLM13	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.9490160712811948	[95]	[133]	7	hSpCas9	negative selection	11522719
45695894	45695917	5	-	28162770	MOLM13	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	-0.23992986696211105	[48]	[29]	-1	hSpCas9	negative selection	11522720
45695721	45695744	5	-	28162770	MOLM13	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.008820228524554	[230]	[82]	-5	hSpCas9	negative selection	11522721
45396606	45396629	5	+	28162770	MOLM13	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.5447973672503603	[346]	[365]	4	hSpCas9	negative selection	11522722
45396552	45396575	5	+	28162770	MOLM13	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	1.056097541769389	[295]	[444]	7	hSpCas9	negative selection	11522723
45396522	45396545	5	+	28162770	MOLM13	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-0.2552704130965968	[103]	[62]	-1	hSpCas9	negative selection	11522724
45396491	45396514	5	-	28162770	MOLM13	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	-1.0060418067878336	[424]	[152]	-5	hSpCas9	negative selection	11522725
45695929	45695952	5	+	28162770	MOLM13	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.5703514152081522	[393]	[422]	4	hSpCas9	negative selection	11522726
45695742	45695765	5	+	28162770	HEL	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-0.1803834059155638	[22]	[12]	-1	hSpCas9	negative selection	11692083
45695910	45695933	5	-	28162770	HEL	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.21508125586657922	[420]	[312]	1	hSpCas9	negative selection	11692084
45461859	45461882	5	+	28162770	HEL	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.4424401815145258	[107]	[93]	3	hSpCas9	negative selection	11692085
45695894	45695917	5	-	28162770	HEL	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	-2.164616090057247	[27]	[3]	-8	hSpCas9	negative selection	11692086
45695721	45695744	5	-	28162770	HEL	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-3.732300599346568	[248]	[11]	-9	hSpCas9	negative selection	11692087
45396606	45396629	5	+	28162770	HEL	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.23473545217006242	[340]	[256]	2	hSpCas9	negative selection	11692088
45396552	45396575	5	+	28162770	HEL	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.9468005060942055	[259]	[320]	8	hSpCas9	negative selection	11692089
45396522	45396545	5	+	28162770	HEL	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-0.7254122796476512	[110]	[42]	-5	hSpCas9	negative selection	11692090
45396491	45396514	5	-	28162770	HEL	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.8392989599461361	[321]	[368]	7	hSpCas9	negative selection	11692091
45695929	45695952	5	+	28162770	HEL	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.11917687594334403	[344]	[239]	1	hSpCas9	negative selection	11692092
45695742	45695765	5	+	28162770	MV411	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.3405469551742568	[14]	[15]	3	hSpCas9	negative selection	11861449
45695910	45695933	5	-	28162770	MV411	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.6643770873059938	[378]	[505]	6	hSpCas9	negative selection	11861450
45461859	45461882	5	+	28162770	MV411	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.5844725380603462	[56]	[71]	5	hSpCas9	negative selection	11861451
45695894	45695917	5	-	28162770	MV411	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	0.10993402703284039	[21]	[19]	0	hSpCas9	negative selection	11861452
45695721	45695744	5	-	28162770	MV411	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.15740418139018	[187]	[70]	-6	hSpCas9	negative selection	11861453
45396606	45396629	5	+	28162770	MV411	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.7363982316265778	[232]	[326]	6	hSpCas9	negative selection	11861454
45396552	45396575	5	+	28162770	MV411	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.9264199608425729	[197]	[316]	8	hSpCas9	negative selection	11861455
45396522	45396545	5	+	28162770	MV411	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-1.0521227310761325	[95]	[38]	-6	hSpCas9	negative selection	11861456
45396491	45396514	5	-	28162770	MV411	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	-0.528046855987807	[290]	[169]	-4	hSpCas9	negative selection	11861457
45695929	45695952	5	+	28162770	MV411	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.7357745050938509	[282]	[396]	6	hSpCas9	negative selection	11861458
45695742	45695765	5	+	28162770	MONOMAC1	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.6774322708565874	[5]	[10]	6	hSpCas9	negative selection	12030815
45695910	45695933	5	-	28162770	MONOMAC1	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.2180006522192901	[191]	[255]	2	hSpCas9	negative selection	12030816
45461859	45461882	5	+	28162770	MONOMAC1	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	0.5228552337477113	[33]	[55]	5	hSpCas9	negative selection	12030817
45695894	45695917	5	-	28162770	MONOMAC1	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	-1.2750393590608269	[18]	[8]	-7	hSpCas9	negative selection	12030818
45695721	45695744	5	-	28162770	MONOMAC1	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	0.9258199007259799	[89]	[195]	8	hSpCas9	negative selection	12030819
45396606	45396629	5	+	28162770	MONOMAC1	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.5519013887727285	[143]	[241]	5	hSpCas9	negative selection	12030820
45396552	45396575	5	+	28162770	MONOMAC1	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	1.1839117616400092	[90]	[236]	8	hSpCas9	negative selection	12030821
45396522	45396545	5	+	28162770	MONOMAC1	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	0.2101385344463198	[45]	[60]	2	hSpCas9	negative selection	12030822
45396491	45396514	5	-	28162770	MONOMAC1	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	1.1062755696604616	[155]	[384]	8	hSpCas9	negative selection	12030823
45695929	45695952	5	+	28162770	MONOMAC1	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	-0.19703684705955382	[152]	[152]	-2	hSpCas9	negative selection	12030824
45695742	45695765	5	+	28162770	OCIAML2	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	-2.318626731797111	[8]	[9]	-8	hSpCas9	negative selection	12200181
45695910	45695933	5	-	28162770	OCIAML2	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	0.5563372223581082	[52]	[431]	5	hSpCas9	negative selection	12200182
45461859	45461882	5	+	28162770	OCIAML2	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	-0.14870173035479906	[12]	[64]	-1	hSpCas9	negative selection	12200183
45695894	45695917	5	-	28162770	OCIAML2	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	-0.47062982524216146	[2]	[11]	-4	hSpCas9	negative selection	12200184
45695721	45695744	5	-	28162770	OCIAML2	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-1.8679653227875461	[26]	[40]	-8	hSpCas9	negative selection	12200185
45396606	45396629	5	+	28162770	OCIAML2	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.6238877735421287	[47]	[409]	6	hSpCas9	negative selection	12200186
45396552	45396575	5	+	28162770	OCIAML2	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.5164311190503406	[27]	[221]	5	hSpCas9	negative selection	12200187
45396522	45396545	5	+	28162770	OCIAML2	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-1.885667324521005	[17]	[26]	-8	hSpCas9	negative selection	12200188
45396491	45396514	5	-	28162770	OCIAML2	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	-0.0469482315540658	[51]	[278]	0	hSpCas9	negative selection	12200189
45695929	45695952	5	+	28162770	OCIAML2	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	0.8512982696452011	[41]	[419]	7	hSpCas9	negative selection	12200190
45695742	45695765	5	+	28162770	OCIAML3	viability	TCTGGCTCCCAAACATGCGGAGG	HCN1	ENSG00000164588	0.4059923596758366	[2]	[11]	4	hSpCas9	negative selection	12369547
45695910	45695933	5	-	28162770	OCIAML3	viability	CAACTCCGTGTGCTTCAAGGTGG	HCN1	ENSG00000164588	-0.056506493309276595	[102]	[298]	0	hSpCas9	negative selection	12369548
45461859	45461882	5	+	28162770	OCIAML3	viability	AAAGACACCCAGCAATCTGGTGG	HCN1	ENSG00000164588	1.6484859870687942	[27]	[264]	9	hSpCas9	negative selection	12369549
45695894	45695917	5	-	28162770	OCIAML3	viability	AAGGTGGACGGCGGTGGCGGCGG	HCN1	ENSG00000164588	-3.5940076403241634	[3]	[0]	-9	hSpCas9	negative selection	12369550
45695721	45695744	5	-	28162770	OCIAML3	viability	GAAGGCGGTGGAAAAGGAGCAGG	HCN1	ENSG00000164588	-0.6949365491749437	[36]	[68]	-5	hSpCas9	negative selection	12369551
45396606	45396629	5	+	28162770	OCIAML3	viability	GAGGTCAGACATGCTGACTGGGG	HCN1	ENSG00000164588	0.15322628929587018	[55]	[187]	1	hSpCas9	negative selection	12369552
45396552	45396575	5	+	28162770	OCIAML3	viability	GACAAACATGGCATAGCAGGTGG	HCN1	ENSG00000164588	0.07401060012455155	[44]	[142]	0	hSpCas9	negative selection	12369553
45396522	45396545	5	+	28162770	OCIAML3	viability	CAGAGACTGGATTAAAGCGGTGG	HCN1	ENSG00000164588	-1.4471662519948922	[27]	[30]	-7	hSpCas9	negative selection	12369554
45396491	45396514	5	-	28162770	OCIAML3	viability	GAGGCGGCAGTATCAAGAGAAGG	HCN1	ENSG00000164588	0.6424325554979176	[72]	[343]	6	hSpCas9	negative selection	12369555
45695929	45695952	5	+	28162770	OCIAML3	viability	GTTGCCGTGCTCCTTCGCGCCGG	HCN1	ENSG00000164588	-0.21785915443891435	[93]	[243]	-2	hSpCas9	negative selection	12369556