Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10021
• Symbol:HCN4
• Description:hyperpolarization activated cyclic nucleotide gated potassium channel 4

DataSource: http://genomecrispr.dkfz.de/#!/results/HCN4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
73368171	73368194	15	-	26472758	Jiyoye	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.7856870047596034	[29]	[38]	5	hSpCas9	negative selection	69655
73325287	73325310	15	+	26472758	Jiyoye	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.8740518123043355	[122]	[169]	6	hSpCas9	negative selection	69656
73367881	73367904	15	-	26472758	Jiyoye	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.3086855181065101	[196]	[183]	2	hSpCas9	negative selection	69657
73367697	73367720	15	-	26472758	Jiyoye	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	0.5863999436859477	[188]	[213]	4	hSpCas9	negative selection	69658
73367550	73367573	15	-	26472758	Jiyoye	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.6425534444368018	[78]	[92]	5	hSpCas9	negative selection	69659
73343709	73343732	15	-	26472758	Jiyoye	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.2926156172430179	[261]	[241]	2	hSpCas9	negative selection	69660
73343495	73343518	15	-	26472758	Jiyoye	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-0.09871554822408402	[70]	[49]	0	hSpCas9	negative selection	69661
73343477	73343500	15	-	26472758	Jiyoye	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	-0.40149167801452146	[274]	[156]	-3	hSpCas9	negative selection	69662
73332130	73332153	15	-	26472758	Jiyoye	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	6.515699838284042	[0]	[68]	9	hSpCas9	negative selection	69663
73325297	73325320	15	-	26472758	Jiyoye	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.4209811810309039	[103]	[104]	3	hSpCas9	negative selection	69664
73368171	73368194	15	-	26472758	KBM7	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.14399512257521296	[88,66]	[46,33]	1	hSpCas9	negative selection	260773
73325287	73325310	15	+	26472758	KBM7	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	-0.3019930646246036	[986,862]	[293,403]	-3	hSpCas9	negative selection	260774
73367881	73367904	15	-	26472758	KBM7	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.10522644100805495	[863,570]	[249,360]	-1	hSpCas9	negative selection	260775
73367697	73367720	15	-	26472758	KBM7	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.42526828512931264	[950,753]	[193,387]	-4	hSpCas9	negative selection	260776
73367550	73367573	15	-	26472758	KBM7	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	-0.39934526811286486	[384,283]	[155,83]	-4	hSpCas9	negative selection	260777
73343709	73343732	15	-	26472758	KBM7	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.15607484903770663	[978,607]	[420,395]	1	hSpCas9	negative selection	260778
73343495	73343518	15	-	26472758	KBM7	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.24936659900010893	[322,220]	[114,180]	2	hSpCas9	negative selection	260779
73343477	73343500	15	-	26472758	KBM7	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	-0.2714680042621448	[745,417]	[215,225]	-3	hSpCas9	negative selection	260780
73332130	73332153	15	-	26472758	KBM7	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-0.334373077022586	[346,410]	[81,197]	-3	hSpCas9	negative selection	260781
73325297	73325320	15	-	26472758	KBM7	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.545640615041368	[419,261]	[264,197]	6	hSpCas9	negative selection	260782
73368171	73368194	15	-	26472758	Raji	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	1.3573617883819469	[36]	[21]	9	hSpCas9	negative selection	451891
73325287	73325310	15	+	26472758	Raji	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.5864375275235982	[550]	[191]	5	hSpCas9	negative selection	451892
73367881	73367904	15	-	26472758	Raji	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.6968615172172485	[318]	[119]	6	hSpCas9	negative selection	451893
73367697	73367720	15	-	26472758	Raji	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	0.604456803518455	[563]	[198]	6	hSpCas9	negative selection	451894
73367550	73367573	15	-	26472758	Raji	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	-0.12783292632043214	[225]	[47]	-1	hSpCas9	negative selection	451895
73343709	73343732	15	-	26472758	Raji	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.1847256239067644	[344]	[90]	1	hSpCas9	negative selection	451896
73343495	73343518	15	-	26472758	Raji	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-0.20577434988603083	[163]	[32]	-2	hSpCas9	negative selection	451897
73343477	73343500	15	-	26472758	Raji	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.41153692853298607	[391]	[120]	4	hSpCas9	negative selection	451898
73332130	73332153	15	-	26472758	Raji	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-0.5889400742952606	[174]	[26]	-5	hSpCas9	negative selection	451899
73325297	73325320	15	-	26472758	Raji	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.7769938617380411	[170]	[67]	7	hSpCas9	negative selection	451900
73368171	73368194	15	-	26472758	K562	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.10948914758033812	[55]	[50]	0	hSpCas9	negative selection	643009
73325287	73325310	15	+	26472758	K562	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.3169312274508147	[678]	[713]	2	hSpCas9	negative selection	643010
73367881	73367904	15	-	26472758	K562	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.7467891015236906	[652]	[924]	6	hSpCas9	negative selection	643011
73367697	73367720	15	-	26472758	K562	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	0.1699405117071704	[794]	[754]	1	hSpCas9	negative selection	643012
73367550	73367573	15	-	26472758	K562	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	-0.04163233089231888	[277]	[227]	0	hSpCas9	negative selection	643013
73343709	73343732	15	-	26472758	K562	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.4185090713655048	[537]	[606]	3	hSpCas9	negative selection	643014
73343495	73343518	15	-	26472758	K562	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.7323567739927384	[245]	[344]	6	hSpCas9	negative selection	643015
73343477	73343500	15	-	26472758	K562	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.8062976152745617	[461]	[681]	6	hSpCas9	negative selection	643016
73332130	73332153	15	-	26472758	K562	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	0.17141689672354016	[303]	[288]	1	hSpCas9	negative selection	643017
73325297	73325320	15	-	26472758	K562	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.8961152173547869	[344]	[541]	7	hSpCas9	negative selection	643018
73324976	73324999	15	-	26627737	DLD1	viability	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.4044975182950383	[133]	[59,49,55]	4	hSpCas9	negative selection	791628
73325432	73325455	15	-	26627737	DLD1	viability	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	1.0108030020513845	[290]	[146,246,161]	8	hSpCas9	negative selection	791629
73329684	73329707	15	+	26627737	DLD1	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.11737381869426633	[790]	[225,302,275]	1	hSpCas9	negative selection	791630
73332239	73332262	15	+	26627737	DLD1	viability	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-0.1462924904692987	[540]	[210,145,107]	-1	hSpCas9	negative selection	791631
73343459	73343482	15	+	26627737	DLD1	viability	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	0.35295796869916696	[206]	[129,57,61]	3	hSpCas9	negative selection	791632
73367881	73367904	15	-	26627737	DLD1	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.06501670175831942	[139]	[73,50,16]	0	hSpCas9	negative selection	791633
73324976	73324999	15	-	26627737	GBM cells	viability after 5 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.23660928563136452	[181]	[122,106]	3	hSpCas9	negative selection	873943
73325432	73325455	15	-	26627737	GBM cells	viability after 5 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	-0.5462256561825772	[225]	[98,66]	-7	hSpCas9	negative selection	873944
73329684	73329707	15	+	26627737	GBM cells	viability after 5 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.17058719899335223	[332]	[162,238]	2	hSpCas9	negative selection	873945
73332239	73332262	15	+	26627737	GBM cells	viability after 5 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-0.044502596747946835	[249]	[128,130]	0	hSpCas9	negative selection	873946
73343459	73343482	15	+	26627737	GBM cells	viability after 5 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	0.31395137416452923	[71]	[50,44]	5	hSpCas9	negative selection	873947
73367881	73367904	15	-	26627737	GBM cells	viability after 5 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.35834549352298295	[103]	[69,72]	5	hSpCas9	negative selection	873948
73324976	73324999	15	-	26627737	GBM cells	viability after 13 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.6328052385335241	[181]	[183,127]	7	hSpCas9	negative selection	956258
73325432	73325455	15	-	26627737	GBM cells	viability after 13 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.00822843475931026	[225]	[151,99]	0	hSpCas9	negative selection	956259
73329684	73329707	15	+	26627737	GBM cells	viability after 13 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.4429519750732644	[332]	[222,263]	5	hSpCas9	negative selection	956260
73332239	73332262	15	+	26627737	GBM cells	viability after 13 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.4196769285965451	[249]	[240,132]	5	hSpCas9	negative selection	956261
73343459	73343482	15	+	26627737	GBM cells	viability after 13 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.3085871495083994	[71]	[109,85]	9	hSpCas9	negative selection	956262
73367881	73367904	15	-	26627737	GBM cells	viability after 13 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.08181987611134134	[103]	[51,65]	1	hSpCas9	negative selection	956263
73324976	73324999	15	-	26627737	GBM cells	viability after 21 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.1410641078912218	[181]	[119,98]	1	hSpCas9	negative selection	1038573
73325432	73325455	15	-	26627737	GBM cells	viability after 21 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	-0.7466119625338566	[225]	[68,76]	-6	hSpCas9	negative selection	1038574
73329684	73329707	15	+	26627737	GBM cells	viability after 21 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.38356590380266925	[332]	[223,246]	4	hSpCas9	negative selection	1038575
73332239	73332262	15	+	26627737	GBM cells	viability after 21 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.3752461756150984	[249]	[183,168]	4	hSpCas9	negative selection	1038576
73343459	73343482	15	+	26627737	GBM cells	viability after 21 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.4580537310927948	[71]	[119,95]	9	hSpCas9	negative selection	1038577
73367881	73367904	15	-	26627737	GBM cells	viability after 21 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.5364492340955704	[103]	[39,37]	-5	hSpCas9	negative selection	1038578
73324976	73324999	15	-	26627737	RPE1	viability after 9 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.47643895510641393	[646]	[221,358]	3	hSpCas9	negative selection	1120888
73325432	73325455	15	-	26627737	RPE1	viability after 9 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.15874957486044033	[594]	[148,283]	1	hSpCas9	negative selection	1120889
73329684	73329707	15	+	26627737	RPE1	viability after 9 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.16830987815721687	[1155]	[225,445]	-1	hSpCas9	negative selection	1120890
73332239	73332262	15	+	26627737	RPE1	viability after 9 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	1.2379379190739668	[458]	[272,423]	7	hSpCas9	negative selection	1120891
73343459	73343482	15	+	26627737	RPE1	viability after 9 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	0.932882634051455	[376]	[261,177]	6	hSpCas9	negative selection	1120892
73367881	73367904	15	-	26627737	RPE1	viability after 9 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.7666162438238882	[113]	[44,80]	5	hSpCas9	negative selection	1120893
73324976	73324999	15	-	26627737	RPE1	viability after 12 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.1434520104017867	[646]	[225,155]	1	hSpCas9	negative selection	1203203
73325432	73325455	15	-	26627737	RPE1	viability after 12 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.06652127114081341	[594]	[112,224]	0	hSpCas9	negative selection	1203204
73329684	73329707	15	+	26627737	RPE1	viability after 12 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-1.0718696982891185	[1155]	[70,228]	-6	hSpCas9	negative selection	1203205
73332239	73332262	15	+	26627737	RPE1	viability after 12 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	1.5387277790037648	[458]	[350,365]	8	hSpCas9	negative selection	1203206
73343459	73343482	15	+	26627737	RPE1	viability after 12 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	0.2582562309100689	[376]	[125,115]	1	hSpCas9	negative selection	1203207
73367881	73367904	15	-	26627737	RPE1	viability after 12 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	1.2348628715397298	[113]	[40,104]	7	hSpCas9	negative selection	1203208
73324976	73324999	15	-	26627737	RPE1	viability after 15 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.7175948259564036	[646]	[358,244]	4	hSpCas9	negative selection	1285518
73325432	73325455	15	-	26627737	RPE1	viability after 15 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.41686804560617047	[594]	[353,99]	2	hSpCas9	negative selection	1285519
73329684	73329707	15	+	26627737	RPE1	viability after 15 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.4540454793127465	[1155]	[282,195]	-3	hSpCas9	negative selection	1285520
73332239	73332262	15	+	26627737	RPE1	viability after 15 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	1.4789558568901033	[458]	[365,357]	7	hSpCas9	negative selection	1285521
73343459	73343482	15	+	26627737	RPE1	viability after 15 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	-0.5522676685031351	[376]	[59,84]	-3	hSpCas9	negative selection	1285522
73367881	73367904	15	-	26627737	RPE1	viability after 15 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.9523957518536812	[113]	[95,29]	6	hSpCas9	negative selection	1285523
73324976	73324999	15	-	26627737	RPE1	viability after 18 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.9308496926284333	[646]	[226,445]	5	hSpCas9	negative selection	1367833
73325432	73325455	15	-	26627737	RPE1	viability after 18 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.10006144500989544	[594]	[247,90]	0	hSpCas9	negative selection	1367834
73329684	73329707	15	+	26627737	RPE1	viability after 18 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.07222808795704388	[1155]	[390,195]	0	hSpCas9	negative selection	1367835
73332239	73332262	15	+	26627737	RPE1	viability after 18 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	1.247641297202618	[458]	[297,289]	7	hSpCas9	negative selection	1367836
73343459	73343482	15	+	26627737	RPE1	viability after 18 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	0.4821498235674	[376]	[261,13]	3	hSpCas9	negative selection	1367837
73367881	73367904	15	-	26627737	RPE1	viability after 18 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	1.6813615054155948	[113]	[59,139]	8	hSpCas9	negative selection	1367838
73324976	73324999	15	-	26627737	HeLa	viability after 8 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.26521445458939	[242]	[218,92,91]	2	hSpCas9	negative selection	1450148
73325432	73325455	15	-	26627737	HeLa	viability after 8 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.33137455475748145	[271]	[181,92,176]	3	hSpCas9	negative selection	1450149
73329684	73329707	15	+	26627737	HeLa	viability after 8 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.22629340938838172	[663]	[345,217,201]	-2	hSpCas9	negative selection	1450150
73332239	73332262	15	+	26627737	HeLa	viability after 8 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.6884285234282889	[268]	[193,212,161]	6	hSpCas9	negative selection	1450151
73343459	73343482	15	+	26627737	HeLa	viability after 8 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	2.197400893815372	[37]	[84,45,96]	9	hSpCas9	negative selection	1450152
73367881	73367904	15	-	26627737	HeLa	viability after 8 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.11824516050236111	[138]	[149,12,26]	-1	hSpCas9	negative selection	1450153
73324976	73324999	15	-	26627737	HeLa	viability after 12 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.7657536901972979	[242]	[93,217,192]	6	hSpCas9	negative selection	1532463
73325432	73325455	15	-	26627737	HeLa	viability after 12 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.7666982675600974	[271]	[243,174,157]	6	hSpCas9	negative selection	1532464
73329684	73329707	15	+	26627737	HeLa	viability after 12 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.4160469125415008	[663]	[48,171,394]	-4	hSpCas9	negative selection	1532465
73332239	73332262	15	+	26627737	HeLa	viability after 12 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.947968373452365	[268]	[238,271,126]	7	hSpCas9	negative selection	1532466
73343459	73343482	15	+	26627737	HeLa	viability after 12 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	2.744987735847051	[37]	[14,144,148]	9	hSpCas9	negative selection	1532467
73367881	73367904	15	-	26627737	HeLa	viability after 12 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.9612932980411525	[138]	[176,30,137]	7	hSpCas9	negative selection	1532468
73324976	73324999	15	-	26627737	HeLa	viability after 15 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	1.3058475937196412	[242]	[442,117,163]	8	hSpCas9	negative selection	1614778
73325432	73325455	15	-	26627737	HeLa	viability after 15 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.025158757022440414	[271]	[191,104,33]	0	hSpCas9	negative selection	1614779
73329684	73329707	15	+	26627737	HeLa	viability after 15 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.6659841469348511	[663]	[140,205,163]	-5	hSpCas9	negative selection	1614780
73332239	73332262	15	+	26627737	HeLa	viability after 15 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.38785332049077986	[268]	[143,164,118]	3	hSpCas9	negative selection	1614781
73343459	73343482	15	+	26627737	HeLa	viability after 15 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	3.1700730018544014	[37]	[105,198,110]	9	hSpCas9	negative selection	1614782
73367881	73367904	15	-	26627737	HeLa	viability after 15 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.4882657481441295	[138]	[129,45,59]	4	hSpCas9	negative selection	1614783
73324976	73324999	15	-	26627737	HeLa	viability after 18 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	1.3453194806769175	[242]	[310,96,163]	8	hSpCas9	negative selection	1697093
73325432	73325455	15	-	26627737	HeLa	viability after 18 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.06553046462864726	[271]	[130,91,33]	0	hSpCas9	negative selection	1697094
73329684	73329707	15	+	26627737	HeLa	viability after 18 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.6412311449045374	[663]	[99,170,163]	-5	hSpCas9	negative selection	1697095
73332239	73332262	15	+	26627737	HeLa	viability after 18 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.4189925741165392	[268]	[99,139,118]	3	hSpCas9	negative selection	1697096
73343459	73343482	15	+	26627737	HeLa	viability after 18 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	3.1915160544586403	[37]	[70,169,110]	9	hSpCas9	negative selection	1697097
73367881	73367904	15	-	26627737	HeLa	viability after 18 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.5279203195685486	[138]	[93,34,59]	4	hSpCas9	negative selection	1697098
73324976	73324999	15	-	26627737	HCT116	viability after 6 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-1.0309605968204525	[655]	[34,58]	-5	hSpCas9	negative selection	1779408
73325432	73325455	15	-	26627737	HCT116	viability after 6 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	-4.435778383387758	[718]	[1,6]	-9	hSpCas9	negative selection	1779409
73329684	73329707	15	+	26627737	HCT116	viability after 6 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.944329067465115	[429]	[44,176]	5	hSpCas9	negative selection	1779410
73332239	73332262	15	+	26627737	HCT116	viability after 6 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-0.815645505903232	[1227]	[148,87]	-5	hSpCas9	negative selection	1779411
73343459	73343482	15	+	26627737	HCT116	viability after 6 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.0212869063821512	[231]	[171,19]	5	hSpCas9	negative selection	1779412
73367881	73367904	15	-	26627737	HCT116	viability after 6 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-1.2840705770255934	[540]	[90,3]	-6	hSpCas9	negative selection	1779413
73324976	73324999	15	-	26627737	HCT116	viability after 8 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-0.38791266381991973	[390]	[150,200,141]	-4	hSpCas9	negative selection	1861723
73325432	73325455	15	-	26627737	HCT116	viability after 8 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.5188061167332978	[256]	[91,169,342]	5	hSpCas9	negative selection	1861724
73329684	73329707	15	+	26627737	HCT116	viability after 8 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.1542538607229494	[360]	[226,198,237]	1	hSpCas9	negative selection	1861725
73332239	73332262	15	+	26627737	HCT116	viability after 8 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.11566495350355283	[410]	[263,353,119]	1	hSpCas9	negative selection	1861726
73343459	73343482	15	+	26627737	HCT116	viability after 8 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.7273638940380829	[55]	[66,144,93]	9	hSpCas9	negative selection	1861727
73367881	73367904	15	-	26627737	HCT116	viability after 8 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-1.1039572159677529	[326]	[113,51,85]	-8	hSpCas9	negative selection	1861728
73324976	73324999	15	-	26627737	HCT116	viability after 9 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-1.7441462555479765	[655]	[39,61]	-8	hSpCas9	negative selection	1944038
73325432	73325455	15	-	26627737	HCT116	viability after 9 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	-2.869499011108998	[718]	[37,16]	-9	hSpCas9	negative selection	1944039
73329684	73329707	15	+	26627737	HCT116	viability after 9 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.3278948493927782	[429]	[204,95]	2	hSpCas9	negative selection	1944040
73332239	73332262	15	+	26627737	HCT116	viability after 9 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-0.48246976760914173	[1227]	[332,156]	-3	hSpCas9	negative selection	1944041
73343459	73343482	15	+	26627737	HCT116	viability after 9 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	0.5342332499418394	[231]	[39,128]	4	hSpCas9	negative selection	1944042
73367881	73367904	15	-	26627737	HCT116	viability after 9 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.32764932355195875	[540]	[218,32]	-2	hSpCas9	negative selection	1944043
73324976	73324999	15	-	26627737	HCT116	viability after 12 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-0.7779089354621266	[390]	[120,143,94]	-7	hSpCas9	negative selection	2026353
73325432	73325455	15	-	26627737	HCT116	viability after 12 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.8682991901309435	[256]	[180,187,374]	7	hSpCas9	negative selection	2026354
73329684	73329707	15	+	26627737	HCT116	viability after 12 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.2479352610861682	[360]	[229,247,197]	2	hSpCas9	negative selection	2026355
73332239	73332262	15	+	26627737	HCT116	viability after 12 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.026483592264825495	[410]	[159,250,254]	0	hSpCas9	negative selection	2026356
73343459	73343482	15	+	26627737	HCT116	viability after 12 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.826012035709896	[55]	[56,178,82]	9	hSpCas9	negative selection	2026357
73367881	73367904	15	-	26627737	HCT116	viability after 12 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-1.482665879440696	[326]	[65,16,99]	-9	hSpCas9	negative selection	2026358
73324976	73324999	15	-	26627737	HCT116	viability after 15 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-0.7515451674010046	[390]	[172,185,46]	-6	hSpCas9	negative selection	2108668
73325432	73325455	15	-	26627737	HCT116	viability after 15 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.7831413039547157	[256]	[285,236,242]	6	hSpCas9	negative selection	2108669
73329684	73329707	15	+	26627737	HCT116	viability after 15 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.14969105796587362	[360]	[321,218,160]	1	hSpCas9	negative selection	2108670
73332239	73332262	15	+	26627737	HCT116	viability after 15 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-0.10335029493637077	[410]	[129,278,238]	-1	hSpCas9	negative selection	2108671
73343459	73343482	15	+	26627737	HCT116	viability after 15 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	2.308277595486965	[55]	[31,239,189]	9	hSpCas9	negative selection	2108672
73367881	73367904	15	-	26627737	HCT116	viability after 15 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-2.8674862730673705	[326]	[54,19,5]	-9	hSpCas9	negative selection	2108673
73324976	73324999	15	-	26627737	HCT116	viability after 18 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-0.2679428397639765	[390]	[64,262,134]	-2	hSpCas9	negative selection	2190983
73325432	73325455	15	-	26627737	HCT116	viability after 18 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.9334818735041064	[256]	[120,266,325]	7	hSpCas9	negative selection	2190984
73329684	73329707	15	+	26627737	HCT116	viability after 18 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.2673551081310382	[360]	[202,282,135]	2	hSpCas9	negative selection	2190985
73332239	73332262	15	+	26627737	HCT116	viability after 18 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.1775852367761271	[410]	[107,316,243]	1	hSpCas9	negative selection	2190986
73343459	73343482	15	+	26627737	HCT116	viability after 18 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	2.3306039313503306	[55]	[113,149,143]	9	hSpCas9	negative selection	2190987
73367881	73367904	15	-	26627737	HCT116	viability after 18 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-2.359038974093882	[326]	[70,0,21]	-9	hSpCas9	negative selection	2190988
73367523	73367546	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAACAGGAGAGGGTCAAGTCGG	HCN4	ENSG00000138622	-0.3739823033604311	[3,3]	[2,1]	-5	hSpCas9	positive selection	2992845
73329763	73329786	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGGAGTACTGCTTCCCCCAGG	HCN4	ENSG00000138622	0.21937741465878524	[4,4]	[4,5]	4	hSpCas9	positive selection	2992846
73367688	73367711	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATCAAAGTGGAGGGAGGCGCGG	HCN4	ENSG00000138622	-0.4409651806162538	[3,3]	[3,0]	-6	hSpCas9	positive selection	2992847
73343537	73343560	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCATTTCCTCCATCCCCGTGG	HCN4	ENSG00000138622	-0.13988654823585597	[4,4]	[4,3]	-2	hSpCas9	positive selection	2992848
73367523	73367546	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAACAGGAGAGGGTCAAGTCGG	HCN4	ENSG00000138622	0.11765686076911089	[3,3]	[3,2]	2	hSpCas9	positive selection	3060703
73329763	73329786	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGGAGTACTGCTTCCCCCAGG	HCN4	ENSG00000138622	0.06798107127689423	[4,4]	[5,2]	1	hSpCas9	positive selection	3060704
73367688	73367711	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATCAAAGTGGAGGGAGGCGCGG	HCN4	ENSG00000138622	-0.6129957625020755	[3,3]	[2,0]	-8	hSpCas9	positive selection	3060705
73343537	73343560	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCATTTCCTCCATCCCCGTGG	HCN4	ENSG00000138622	-0.06911942793912262	[4,4]	[3,2]	-1	hSpCas9	positive selection	3060706
73332234	73332257		-	24336571	A375	resistance to PLX after 7 days	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.1700236863926763	[20,13]	[15,14]	-5	hSpCas9	positive selection	3118582
73343402	73343425		+	24336571	A375	resistance to PLX after 7 days	TATATCGAATGAGGCGGGAGAGG	HCN4	ENSG00000138622	-0.023297620780274197	[6,5]	[6,5]	0	hSpCas9	positive selection	3118583
73343453	73343476		+	24336571	A375	resistance to PLX after 7 days	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.005510205115483835	[29,31]	[30,29]	0	hSpCas9	positive selection	3118584
73332234	73332257		-	24336571	A375	resistance to PLX after 14 days	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.8772584969015667	[16,23]	[4,4]	-8	hSpCas9	positive selection	3176375
73343402	73343425		+	24336571	A375	resistance to PLX after 14 days	TATATCGAATGAGGCGGGAGAGG	HCN4	ENSG00000138622	-0.26292306743383875	[6,7]	[1,2]	-3	hSpCas9	positive selection	3176376
73343453	73343476		+	24336571	A375	resistance to PLX after 14 days	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.6140884166774117	[23,42]	[9,9]	-7	hSpCas9	positive selection	3176377
73332234	73332257		-	24336571	A375	viability after 7 days	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.06522026610765858	[17]	[20,13]	1	hSpCas9	negative selection	3234168
73343402	73343425		+	24336571	A375	viability after 7 days	TATATCGAATGAGGCGGGAGAGG	HCN4	ENSG00000138622	0.342972733861895	[4]	[6,5]	5	hSpCas9	negative selection	3234169
73343453	73343476		+	24336571	A375	viability after 7 days	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.4838123122300283	[22]	[29,31]	7	hSpCas9	negative selection	3234170
73332234	73332257		-	24336571	A375	viability after 14 days	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.30706743186125696	[17]	[16,23]	4	hSpCas9	negative selection	3291961
73343402	73343425		+	24336571	A375	viability after 14 days	TATATCGAATGAGGCGGGAGAGG	HCN4	ENSG00000138622	0.46135990759296064	[4]	[6,7]	6	hSpCas9	negative selection	3291962
73343453	73343476		+	24336571	A375	viability after 14 days	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.619757515866843	[22]	[23,42]	7	hSpCas9	negative selection	3291963
73343453	73343476	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.47579506484618445	[111,107]	[0,0]	2	hSpCas9	positive selection	3353092
73332234	73332257	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.15420985648233496	[134,139]	[0,0]	0	hSpCas9	positive selection	3353093
73343498	73343521	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.24340503623029236	[121,240]	[0,0]	-1	hSpCas9	positive selection	3353094
73329684	73329707	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.19123702098806272	[133,133]	[0,0]	1	hSpCas9	positive selection	3372283
73329744	73329767	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	0.7654731151161606	[89,89]	[0,0]	4	hSpCas9	positive selection	3372284
73325383	73325406	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.05555674383852015	[158,158]	[0,0]	0	hSpCas9	positive selection	3372285
73367523	73367546	15	-	26780180	HT29	viability (Avana library 4 designs)	CGAACAGGAGAGGGTCAAGTCGG	HCN4	ENSG00000138622	1.95018172574485	[]	[]	7	hSpCas9	negative selection	3430104
73329762	73329785	15	+	26780180	HT29	viability (Avana library 4 designs)	GTAGGAGTACTGCTTCCCCCAGG	HCN4	ENSG00000138622	1.02856221809391	[]	[]	4	hSpCas9	negative selection	3430105
73367688	73367711	15	-	26780180	HT29	viability (Avana library 4 designs)	TATCAAAGTGGAGGGAGGCGCGG	HCN4	ENSG00000138622	0.652274373380849	[]	[]	2	hSpCas9	negative selection	3430106
73343537	73343560	15	-	26780180	HT29	viability (Avana library 4 designs)	TTTCATTTCCTCCATCCCCGTGG	HCN4	ENSG00000138622	-0.0958144875454228	[]	[]	-1	hSpCas9	negative selection	3430107
73343537	73343560	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCATTTCCTCCATCCCCGTGG	HCN4	ENSG00000138622	-2.34551231157759	[]	[]	-3	hSpCas9	negative selection	3515102
73367688	73367711	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATCAAAGTGGAGGGAGGCGCGG	HCN4	ENSG00000138622	0.431374715076104	[]	[]	0	hSpCas9	negative selection	3515103
73329762	73329785	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGAGTACTGCTTCCCCCAGG	HCN4	ENSG00000138622	3.12985630383405	[]	[]	5	hSpCas9	negative selection	3515104
73367523	73367546	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAACAGGAGAGGGTCAAGTCGG	HCN4	ENSG00000138622	5.09876298193374	[]	[]	8	hSpCas9	negative selection	3515105
73329777	73329800	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCACAGAACAACTCCTGGGGG	HCN4	ENSG00000138622	-5.79557899978511	[]	[]	-6	hSpCas9	negative selection	3515106
73343390	73343413	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTCGATATATTCACCAGTGGG	HCN4	ENSG00000138622	-6.44386375631223	[]	[]	-6	hSpCas9	negative selection	3515107
73343537	73343560	15	-	26780180	A375	viability (Avana lentiGuide)	TTTCATTTCCTCCATCCCCGTGG	HCN4	ENSG00000138622	-2.8979393182388	[]	[]	-5	hSpCas9	negative selection	3623761
73367688	73367711	15	-	26780180	A375	viability (Avana lentiGuide)	TATCAAAGTGGAGGGAGGCGCGG	HCN4	ENSG00000138622	-4.05255605880742	[]	[]	-7	hSpCas9	negative selection	3623762
73329762	73329785	15	+	26780180	A375	viability (Avana lentiGuide)	GTAGGAGTACTGCTTCCCCCAGG	HCN4	ENSG00000138622	2.57742292391581	[]	[]	2	hSpCas9	negative selection	3623763
73367523	73367546	15	-	26780180	A375	viability (Avana lentiGuide)	CGAACAGGAGAGGGTCAAGTCGG	HCN4	ENSG00000138622	2.4396167402277	[]	[]	2	hSpCas9	negative selection	3623764
73329777	73329800	15	-	26780180	A375	viability (Avana lentiGuide)	GTCCACAGAACAACTCCTGGGGG	HCN4	ENSG00000138622	8.78854970643471	[]	[]	6	hSpCas9	negative selection	3623765
73343390	73343413	15	-	26780180	A375	viability (Avana lentiGuide)	CATTCGATATATTCACCAGTGGG	HCN4	ENSG00000138622	2.32494527186781	[]	[]	2	hSpCas9	negative selection	3623766
73343537	73343560	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCATTTCCTCCATCCCCGTGG	HCN4	ENSG00000138622	-0.1393435727813243	[5]	[5,4]	-2	hSpCas9	positive selection	3732420
73367688	73367711	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCAAAGTGGAGGGAGGCGCGG	HCN4	ENSG00000138622	0.0411019654576585	[5]	[4,5]	1	hSpCas9	positive selection	3732421
73329762	73329785	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGAGTACTGCTTCCCCCAGG	HCN4	ENSG00000138622	0.09690558621511948	[5]	[5,5]	2	hSpCas9	positive selection	3732422
73367523	73367546	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAACAGGAGAGGGTCAAGTCGG	HCN4	ENSG00000138622	0.2859803638507983	[4]	[5,5]	8	hSpCas9	positive selection	3732423
73329777	73329800	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCACAGAACAACTCCTGGGGG	HCN4	ENSG00000138622	-0.28829028639964105	[4]	[3,3]	-4	hSpCas9	positive selection	3732424
73343390	73343413	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTCGATATATTCACCAGTGGG	HCN4	ENSG00000138622	-0.6060712328177859	[6]	[3,3]	-7	hSpCas9	positive selection	3732425
73343537	73343560	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCATTTCCTCCATCCCCGTGG	HCN4	ENSG00000138622	0.2608211252259045	[6]	[7,6]	7	hSpCas9	positive selection	3841027
73367688	73367711	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCAAAGTGGAGGGAGGCGCGG	HCN4	ENSG00000138622	-0.9644494678005187	[5]	[3,0]	-8	hSpCas9	positive selection	3841028
73329762	73329785	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGAGTACTGCTTCCCCCAGG	HCN4	ENSG00000138622	-0.07062703714577803	[6]	[4,5]	-1	hSpCas9	positive selection	3841029
73367523	73367546	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAACAGGAGAGGGTCAAGTCGG	HCN4	ENSG00000138622	0.17272324517778045	[5]	[4,6]	4	hSpCas9	positive selection	3841030
73329777	73329800	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCACAGAACAACTCCTGGGGG	HCN4	ENSG00000138622	-0.12875715310973454	[5]	[3,4]	-2	hSpCas9	positive selection	3841031
73343390	73343413	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTCGATATATTCACCAGTGGG	HCN4	ENSG00000138622	0.15279709726787627	[5]	[5,5]	3	hSpCas9	positive selection	3841032
73325383	73325406	15	+	26780180	A375	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	1.6912093155477	[]	[]	9	hSpCas9	negative selection	3947092
73329744	73329767	15	+	26780180	A375	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	1.52298464625846	[]	[]	8	hSpCas9	negative selection	3947093
73329684	73329707	15	+	26780180	A375	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	1.26012912039802	[]	[]	6	hSpCas9	negative selection	3947094
73332234	73332257	15	-	26780180	A375	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	1.04503860574791	[]	[]	5	hSpCas9	negative selection	3947095
73343453	73343476	15	+	26780180	A375	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	1.15283604837625	[]	[]	6	hSpCas9	negative selection	3947096
73343498	73343521	15	-	26780180	A375	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.840978535386431	[]	[]	3	hSpCas9	negative selection	3947097
73325383	73325406	15	+	26780180	HT29	viability (GeCKOv2 library)	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	0.936892047163234	[]	[]	4	hSpCas9	negative selection	4055058
73329744	73329767	15	+	26780180	HT29	viability (GeCKOv2 library)	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	2.3111216150178	[]	[]	9	hSpCas9	negative selection	4055059
73329684	73329707	15	+	26780180	HT29	viability (GeCKOv2 library)	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	1.52096729475646	[]	[]	7	hSpCas9	negative selection	4055060
73332234	73332257	15	-	26780180	HT29	viability (GeCKOv2 library)	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.736480341312607	[]	[]	3	hSpCas9	negative selection	4055061
73343453	73343476	15	+	26780180	HT29	viability (GeCKOv2 library)	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	1.55670482642303	[]	[]	7	hSpCas9	negative selection	4055062
73343498	73343521	15	-	26780180	HT29	viability (GeCKOv2 library)	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.404171276463972	[]	[]	1	hSpCas9	negative selection	4055063
73332234	73332257	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.03786269870144333	[3]	[2,2]	1	hSpCas9	positive selection	4142014
73343402	73343425	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATATCGAATGAGGCGGGAGAGG	HCN4	ENSG00000138622	-0.3955405321161514	[3]	[1,0]	-7	hSpCas9	positive selection	4142015
73343453	73343476	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.12140376016862192	[4]	[3,3]	3	hSpCas9	positive selection	4142016
73332234	73332257	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.7067781512079694	[3]	[0,3,1,2]	4	hSpCas9	positive selection	4206036
73343402	73343425	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATATCGAATGAGGCGGGAGAGG	HCN4	ENSG00000138622	-0.2128564613603281	[1]	[0,0,0,0]	-3	hSpCas9	positive selection	4206037
73343453	73343476	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.8342545172271179	[4]	[3,2,3,3]	5	hSpCas9	positive selection	4206038
73343453	73343476	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.2898945330725913	[2]	[3,2]	6	hSpCas9	positive selection	4274661
73332234	73332257	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.4318284555255985	[3]	[3,3]	8	hSpCas9	positive selection	4274662
73343498	73343521	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.34605497711727884	[3]	[2,1]	-6	hSpCas9	positive selection	4274663
73329684	73329707	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.03262718725038953	[2]	[1,2]	0	hSpCas9	positive selection	4338922
73329744	73329767	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.5961851920682866	[2]	[1,0]	-8	hSpCas9	positive selection	4338923
73325383	73325406	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.017392582058293294	[2]	[2,2]	0	hSpCas9	positive selection	4338924
73343421	73343443	15	+	27760321	OCIAML3	viability	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	-0.7241996404725107	[319,298]	[166,119]	-6	hSpCas9	negative selection	4406364
73343495	73343517	15	-	27760321	OCIAML3	viability	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.43799055654283003	[802,705]	[700,923]	5	hSpCas9	negative selection	4406365
73343592	73343614	15	+	27760321	OCIAML3	viability	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.389904870420694	[933,930]	[988,918]	4	hSpCas9	negative selection	4406366
73367705	73367727	15	+	27760321	OCIAML3	viability	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	0.13526537009315096	[403,374]	[272,414]	1	hSpCas9	negative selection	4406367
73367990	73368012	15	+	27760321	OCIAML3	viability	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	-0.18265360242030804	[1003,923]	[648,683]	-2	hSpCas9	negative selection	4406368
73343421	73343443	15	+	27760321	OCIAML2	viability	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.9601246472762686	[319,298]	[416,579]	9	hSpCas9	negative selection	4489827
73343495	73343517	15	-	27760321	OCIAML2	viability	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.3209661845438475	[802,705]	[646,910]	4	hSpCas9	negative selection	4489828
73343592	73343614	15	+	27760321	OCIAML2	viability	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.46223501541294243	[933,930]	[818,1336]	6	hSpCas9	negative selection	4489829
73367705	73367727	15	+	27760321	OCIAML2	viability	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	0.5883218953225485	[403,374]	[412,553]	7	hSpCas9	negative selection	4489830
73367990	73368012	15	+	27760321	OCIAML2	viability	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.1481120769682558	[1003,923]	[731,1037]	2	hSpCas9	negative selection	4489831
73343421	73343443	15	+	27760321	MV411	viability	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	1.5296206094614986	[319,298]	[533,673]	9	hSpCas9	negative selection	4573290
73343495	73343517	15	-	27760321	MV411	viability	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	1.3320126377437482	[802,705]	[493,2387]	8	hSpCas9	negative selection	4573291
73343592	73343614	15	+	27760321	MV411	viability	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.6122181950712648	[933,930]	[1190,571]	4	hSpCas9	negative selection	4573292
73367705	73367727	15	+	27760321	MV411	viability	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	-0.3445823720546167	[403,374]	[42,441]	-2	hSpCas9	negative selection	4573293
73367990	73368012	15	+	27760321	MV411	viability	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	-0.42526083394572733	[1003,923]	[330,687]	-3	hSpCas9	negative selection	4573294
73343421	73343443	15	+	27760321	HL60	viability	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.33974903319542094	[319,298]	[323,315]	4	hSpCas9	negative selection	4656753
73343495	73343517	15	-	27760321	HL60	viability	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.6814260237093618	[802,705]	[951,1022]	7	hSpCas9	negative selection	4656754
73343592	73343614	15	+	27760321	HL60	viability	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.3944950412831667	[933,930]	[952,1058]	5	hSpCas9	negative selection	4656755
73367705	73367727	15	+	27760321	HL60	viability	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	0.5397334496444667	[403,374]	[433,492]	6	hSpCas9	negative selection	4656756
73367990	73368012	15	+	27760321	HL60	viability	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.09433925606773985	[1003,923]	[776,907]	1	hSpCas9	negative selection	4656757
73343421	73343443	15	+	27760321	HT1080	viability	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.5812612899640289	[298,233]	[134,184]	3	hSpCas9	negative selection	4740216
73343495	73343517	15	-	27760321	HT1080	viability	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.9948042616836887	[705,550]	[518,476]	5	hSpCas9	negative selection	4740217
73343592	73343614	15	+	27760321	HT1080	viability	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	-0.1882260507940985	[930,726]	[286,292]	-1	hSpCas9	negative selection	4740218
73367705	73367727	15	+	27760321	HT1080	viability	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	-1.0388873165317714	[374,292]	[122,0]	-4	hSpCas9	negative selection	4740219
73367990	73368012	15	+	27760321	HT1080	viability	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	1.1063553798664505	[923,720]	[893,498]	6	hSpCas9	negative selection	4740220
73343421	73343443	15	+	27760321	HT29	viability after 7 days	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	-0.2706393186741251	[298,233]	[164,294,371]	-4	hSpCas9	negative selection	4823679
73343495	73343517	15	-	27760321	HT29	viability after 7 days	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.22444427520831045	[705,550]	[1166,1015,687]	3	hSpCas9	negative selection	4823680
73343592	73343614	15	+	27760321	HT29	viability after 7 days	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	-0.5301194347458409	[930,726]	[885,565,780]	-6	hSpCas9	negative selection	4823681
73367705	73367727	15	+	27760321	HT29	viability after 7 days	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	-0.011288063439386042	[374,292]	[542,344,406]	0	hSpCas9	negative selection	4823682
73367990	73368012	15	+	27760321	HT29	viability after 7 days	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.1446901159627645	[923,720]	[1476,1114,963]	2	hSpCas9	negative selection	4823683
73343421	73343443	15	+	27760321	HT29	viability after 25 days	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.3625737928641691	[298,233]	[324,345,520]	4	hSpCas9	negative selection	4907142
73343495	73343517	15	-	27760321	HT29	viability after 25 days	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.5894596465792932	[705,550]	[1065,1116,1055]	6	hSpCas9	negative selection	4907143
73343592	73343614	15	+	27760321	HT29	viability after 25 days	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.036961633197888366	[930,726]	[964,848,1115]	0	hSpCas9	negative selection	4907144
73367705	73367727	15	+	27760321	HT29	viability after 25 days	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	0.14910101246511076	[374,292]	[442,280,557]	1	hSpCas9	negative selection	4907145
73367990	73368012	15	+	27760321	HT29	viability after 25 days	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.26086345433604663	[923,720]	[1155,1197,1008]	2	hSpCas9	negative selection	4907146
73343421	73343443	15	+	27760321	HT29	viability after 22 days	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.58530124262091	[298,233]	[325,457,607]	6	hSpCas9	negative selection	4990605
73343495	73343517	15	-	27760321	HT29	viability after 22 days	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.4933153515330051	[705,550]	[938,1168,961]	5	hSpCas9	negative selection	4990606
73343592	73343614	15	+	27760321	HT29	viability after 22 days	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.10338698289980197	[930,726]	[1175,857,1050]	1	hSpCas9	negative selection	4990607
73367705	73367727	15	+	27760321	HT29	viability after 22 days	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	-0.17296233887807633	[374,292]	[300,245,482]	-2	hSpCas9	negative selection	4990608
73367990	73368012	15	+	27760321	HT29	viability after 22 days	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.46794618415090916	[923,720]	[1347,1331,1263]	5	hSpCas9	negative selection	4990609
73343421	73343443	15	+	27760321	HT29	viability after 19 days	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.4639338847840663	[298,233]	[302,288,647]	4	hSpCas9	negative selection	5074068
73343495	73343517	15	-	27760321	HT29	viability after 19 days	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.508397685838067	[705,550]	[744,876,1400]	5	hSpCas9	negative selection	5074069
73343592	73343614	15	+	27760321	HT29	viability after 19 days	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.16823915992256921	[930,726]	[1416,1223,608]	1	hSpCas9	negative selection	5074070
73367705	73367727	15	+	27760321	HT29	viability after 19 days	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	-0.2016851504146283	[374,292]	[377,341,282]	-2	hSpCas9	negative selection	5074071
73367990	73368012	15	+	27760321	HT29	viability after 19 days	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.33392973761231204	[923,720]	[2025,911,723]	3	hSpCas9	negative selection	5074072
73343421	73343443	15	+	27760321	HT29	viability after 16 days	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.4122448231881265	[298,233]	[390,393,404]	4	hSpCas9	negative selection	5157531
73343495	73343517	15	-	27760321	HT29	viability after 16 days	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.30869473404255765	[705,550]	[825,886,894]	3	hSpCas9	negative selection	5157532
73343592	73343614	15	+	27760321	HT29	viability after 16 days	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.15634657896690474	[930,726]	[1177,708,1235]	1	hSpCas9	negative selection	5157533
73367705	73367727	15	+	27760321	HT29	viability after 16 days	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	0.36542505919359924	[374,292]	[650,298,514]	4	hSpCas9	negative selection	5157534
73367990	73368012	15	+	27760321	HT29	viability after 16 days	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.32259428781588406	[923,720]	[1172,1237,1040]	3	hSpCas9	negative selection	5157535
73343421	73343443	15	+	27760321	HT29	viability after 13 days	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.34015732915386365	[298,233]	[374,419,379]	4	hSpCas9	negative selection	5240994
73343495	73343517	15	-	27760321	HT29	viability after 13 days	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.4938372483282323	[705,550]	[964,948,1157]	6	hSpCas9	negative selection	5240995
73343592	73343614	15	+	27760321	HT29	viability after 13 days	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.004035135324577999	[930,726]	[1434,729,740]	0	hSpCas9	negative selection	5240996
73367705	73367727	15	+	27760321	HT29	viability after 13 days	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	-0.16011909601842167	[374,292]	[415,410,220]	-2	hSpCas9	negative selection	5240997
73367990	73368012	15	+	27760321	HT29	viability after 13 days	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.16094103611669652	[923,720]	[1141,1110,953]	2	hSpCas9	negative selection	5240998
73343421	73343443	15	+	27760321	HT29	viability after 10 days	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.24731537498770587	[298,233]	[253,577,358]	3	hSpCas9	negative selection	5324457
73343495	73343517	15	-	27760321	HT29	viability after 10 days	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.4205431126662873	[705,550]	[1198,1029,923]	6	hSpCas9	negative selection	5324458
73343592	73343614	15	+	27760321	HT29	viability after 10 days	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	-0.003083916869811798	[930,726]	[1090,1137,875]	0	hSpCas9	negative selection	5324459
73367705	73367727	15	+	27760321	HT29	viability after 10 days	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	-0.24199449611590895	[374,292]	[205,520,335]	-3	hSpCas9	negative selection	5324460
73367990	73368012	15	+	27760321	HT29	viability after 10 days	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.15049606598912635	[923,720]	[1252,1142,1025]	2	hSpCas9	negative selection	5324461
73343421	73343443	15	+	27760321	MOLM13	viability	GAGGCGTAACAGGCGTAAGAGG	HCN4	ENSG00000138622	0.009185751522694241	[319,298]	[305,64]	0	hSpCas9	negative selection	5407920
73343495	73343517	15	-	27760321	MOLM13	viability	GAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.5440233272160696	[802,705]	[801,463]	4	hSpCas9	negative selection	5407921
73343592	73343614	15	+	27760321	MOLM13	viability	TTTAATCCGCTGCGGGTCCAGG	HCN4	ENSG00000138622	0.6628595904838079	[933,930]	[1190,532]	4	hSpCas9	negative selection	5407922
73367705	73367727	15	+	27760321	MOLM13	viability	TTGATAGCGGTGTCCACCGAGG	HCN4	ENSG00000138622	0.4072390730423393	[403,374]	[452,153]	3	hSpCas9	negative selection	5407923
73367990	73368012	15	+	27760321	MOLM13	viability	CTGCAGTCGCCGTTCGTGCTGG	HCN4	ENSG00000138622	0.046999967278627874	[1003,923]	[812,347]	0	hSpCas9	negative selection	5407924
73368782	73368805	15	+	27661255	K562	viability	GGCCCGTCCGGCCCGTCCCGGGG	HCN4	ENSG00000138622	-0.17891649513183466	[666,599]	[496,405]	-5	dCas9-KRAB	negative selection	5484231
73368802	73368825	15	+	27661255	K562	viability	GGGCTCCCGCCGCAACCGAGCGG	HCN4	ENSG00000138622	0.23456167030377215	[895,825]	[872,756]	7	dCas9-KRAB	negative selection	5484232
73368821	73368844	15	+	27661255	K562	viability	GCGGAGCCCAGCGACCCGCCGGG	HCN4	ENSG00000138622	0.19046943233971625	[665,655]	[633,575]	6	dCas9-KRAB	negative selection	5484233
73368447	73368470	15	-	27661255	K562	viability	GCGAGCCCGGGGACTCGGAGCGG	HCN4	ENSG00000138622	-0.7476268091971867	[432,570]	[255,221]	-8	dCas9-KRAB	negative selection	5484234
73368469	73368492	15	-	27661255	K562	viability	GCCCGGGAGGAGGTGTAGCGCGG	HCN4	ENSG00000138622	-0.4716475357537411	[617,409]	[321,277]	-7	dCas9-KRAB	negative selection	5484235
73368836	73368859	15	-	27661255	K562	viability	GGCCGCTGATGTAAGCCCGGCGG	HCN4	ENSG00000138622	0.21254806564284326	[591,604]	[617,498]	7	dCas9-KRAB	negative selection	5484236
73368839	73368862	15	-	27661255	K562	viability	GGCGGCCGCTGATGTAAGCCCGG	HCN4	ENSG00000138622	-0.46360652654194245	[204,262]	[155,116]	-7	dCas9-KRAB	negative selection	5484237
73343453	73343476	15	+	27260156	BXPC3	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.09341503362999666	[458]	[505,403,521,634]	2	hSpCas9	negative selection	5547121
73332234	73332257	15	-	27260156	BXPC3	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.27002211471234383	[493]	[453,653,653,758]	6	hSpCas9	negative selection	5547122
73343498	73343521	15	-	27260156	BXPC3	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.06978604114427678	[777]	[644,791,799,884]	-2	hSpCas9	negative selection	5547123
73329684	73329707	15	+	27260156	BXPC3	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.1952425053565902	[372]	[400,274,310,373]	-4	hSpCas9	negative selection	5611382
73329744	73329767	15	+	27260156	BXPC3	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.5460779364547632	[352]	[255,174,281,307]	-8	hSpCas9	negative selection	5611383
73325383	73325406	15	+	27260156	BXPC3	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	0.07197276272707456	[453]	[490,511,516,468]	1	hSpCas9	negative selection	5611384
73343453	73343476	15	+	27260156	A673	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.007268114382892862	[458]	[581,504,575,555]	0	hSpCas9	negative selection	5668372
73332234	73332257	15	-	27260156	A673	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.07276904628422672	[493]	[701,626,619,549]	1	hSpCas9	negative selection	5668373
73343498	73343521	15	-	27260156	A673	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.03444862383959035	[777]	[911,945,1073,882]	0	hSpCas9	negative selection	5668374
73329684	73329707	15	+	27260156	A673	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.031659083052547055	[372]	[473,411,411,459]	-1	hSpCas9	negative selection	5732633
73329744	73329767	15	+	27260156	A673	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.5284948613485887	[352]	[281,282,307,300]	-8	hSpCas9	negative selection	5732634
73325383	73325406	15	+	27260156	A673	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.06463134494738831	[453]	[551,507,520,505]	-2	hSpCas9	negative selection	5732635
73343453	73343476	15	+	27260156	A375	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.04069412162534445	[458]	[461,655,525,463]	0	hSpCas9	negative selection	5789623
73332234	73332257	15	-	27260156	A375	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.09133915196246199	[493]	[542,937,489,538]	1	hSpCas9	negative selection	5789624
73343498	73343521	15	-	27260156	A375	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.06630768007185128	[777]	[809,1013,1147,849]	0	hSpCas9	negative selection	5789625
73329684	73329707	15	+	27260156	A375	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.8003241626709474	[372]	[296,222,269,210]	-7	hSpCas9	negative selection	5853884
73329744	73329767	15	+	27260156	A375	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.9956105566871012	[352]	[142,229,183,264]	-8	hSpCas9	negative selection	5853885
73325383	73325406	15	+	27260156	A375	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.07278259412550972	[453]	[583,467,358,588]	-1	hSpCas9	negative selection	5853886
73343453	73343476	15	+	27260156	COLO741	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.11000499903229746	[458]	[576,569,488]	-2	hSpCas9	negative selection	5910874
73332234	73332257	15	-	27260156	COLO741	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.07152468879633163	[493]	[614,812,563]	1	hSpCas9	negative selection	5910875
73343498	73343521	15	-	27260156	COLO741	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.030502445709424064	[777]	[973,821,1110]	0	hSpCas9	negative selection	5910876
73329684	73329707	15	+	27260156	COLO741	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.032366093301512744	[372]	[666,494,266]	0	hSpCas9	negative selection	5975135
73329744	73329767	15	+	27260156	COLO741	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.9501300638298491	[352]	[211,251,233]	-9	hSpCas9	negative selection	5975136
73325383	73325406	15	+	27260156	COLO741	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	0.014587353797844267	[453]	[605,492,653]	0	hSpCas9	negative selection	5975137
73343453	73343476	15	+	27260156	CAL120	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.3231979440822737	[458]	[798,631,724]	5	hSpCas9	negative selection	6032125
73332234	73332257	15	-	27260156	CAL120	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.19866490156464894	[493]	[600,545,948]	3	hSpCas9	negative selection	6032126
73343498	73343521	15	-	27260156	CAL120	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.2195421003598801	[777]	[1344,881,1185]	3	hSpCas9	negative selection	6032127
73329684	73329707	15	+	27260156	CAL120	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.39379865279773596	[372]	[396,330,1060]	6	hSpCas9	negative selection	6096386
73329744	73329767	15	+	27260156	CAL120	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.3488667415219717	[352]	[279,165,88]	-9	hSpCas9	negative selection	6096387
73325383	73325406	15	+	27260156	CAL120	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.11253447254562204	[453]	[477,517,563]	-2	hSpCas9	negative selection	6096388
73343453	73343476	15	+	27260156	CADOES1	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.06903964777386251	[458]	[468,439,490,388]	1	hSpCas9	negative selection	6153376
73332234	73332257	15	-	27260156	CADOES1	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.3059180581373447	[493]	[389,545,519,825]	5	hSpCas9	negative selection	6153377
73343498	73343521	15	-	27260156	CADOES1	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.09285930309600643	[777]	[493,511,951,758]	-1	hSpCas9	negative selection	6153378
73329684	73329707	15	+	27260156	CADOES1	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.1400294600915743	[372]	[411,300,282,260]	-2	hSpCas9	negative selection	6217637
73329744	73329767	15	+	27260156	CADOES1	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.4946783694477807	[352]	[384,184,244,111]	-7	hSpCas9	negative selection	6217638
73325383	73325406	15	+	27260156	CADOES1	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.4745658408762195	[453]	[349,286,207,372]	-7	hSpCas9	negative selection	6217639
73343453	73343476	15	+	27260156	EWS502	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.12200193320519606	[458]	[522,440,640,513]	2	hSpCas9	negative selection	6274627
73332234	73332257	15	-	27260156	EWS502	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.01739206791239084	[493]	[459,567,463,637]	0	hSpCas9	negative selection	6274628
73343498	73343521	15	-	27260156	EWS502	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.12726322774625487	[777]	[828,993,879,897]	2	hSpCas9	negative selection	6274629
73329684	73329707	15	+	27260156	EWS502	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.06570265117936797	[372]	[314,335,495,371]	-1	hSpCas9	negative selection	6338888
73329744	73329767	15	+	27260156	EWS502	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.8049527807792196	[352]	[194,224,193,244]	-8	hSpCas9	negative selection	6338889
73325383	73325406	15	+	27260156	EWS502	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.2318156559498775	[453]	[336,470,342,496]	-4	hSpCas9	negative selection	6338890
73343453	73343476	15	+	27260156	EW8	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.10909498699075082	[458]	[385,472,223,548]	2	hSpCas9	negative selection	6395878
73332234	73332257	15	-	27260156	EW8	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.0897459465869251	[493]	[338,328,388,439]	-2	hSpCas9	negative selection	6395879
73343498	73343521	15	-	27260156	EW8	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.06476451357850332	[777]	[845,570,546,710]	1	hSpCas9	negative selection	6395880
73329684	73329707	15	+	27260156	EW8	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.47596193929840785	[372]	[193,198,258,206]	-7	hSpCas9	negative selection	6460139
73329744	73329767	15	+	27260156	EW8	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.5243331530351139	[352]	[207,257,135,204]	-7	hSpCas9	negative selection	6460140
73325383	73325406	15	+	27260156	EW8	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.2006321276483424	[453]	[376,300,259,357]	-4	hSpCas9	negative selection	6460141
73343453	73343476	15	+	27260156	CORL105	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.04259668199189654	[458]	[470,489,625,635]	0	hSpCas9	negative selection	6517129
73332234	73332257	15	-	27260156	CORL105	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.23619000987131666	[493]	[545,584,694,896]	4	hSpCas9	negative selection	6517130
73343498	73343521	15	-	27260156	CORL105	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.15071023854315746	[777]	[779,839,878,789]	-3	hSpCas9	negative selection	6517131
73329684	73329707	15	+	27260156	CORL105	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.2103573761861372	[372]	[356,364,433,361]	-4	hSpCas9	negative selection	6581390
73329744	73329767	15	+	27260156	CORL105	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.018593807713862	[352]	[236,239,187,148]	-9	hSpCas9	negative selection	6581391
73325383	73325406	15	+	27260156	CORL105	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	0.07351370186245798	[453]	[660,499,510,561]	1	hSpCas9	negative selection	6581392
73343453	73343476	15	+	27260156	HS294T	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.14708836118569948	[458]	[127,236,120,153]	-2	hSpCas9	negative selection	6638380
73332234	73332257	15	-	27260156	HS294T	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.5971843943549259	[493]	[356,269,271,241]	7	hSpCas9	negative selection	6638381
73343498	73343521	15	-	27260156	HS294T	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.03732852431288891	[777]	[226,296,374,275]	0	hSpCas9	negative selection	6638382
73329684	73329707	15	+	27260156	HS294T	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.010531834381661609	[372]	[130,153,164,128]	0	hSpCas9	negative selection	6702641
73329744	73329767	15	+	27260156	HS294T	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.11925579233009725	[352]	[34,41,320,113]	-2	hSpCas9	negative selection	6702642
73325383	73325406	15	+	27260156	HS294T	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.1968987471485216	[453]	[101,95,287,128]	-3	hSpCas9	negative selection	6702643
73343453	73343476	15	+	27260156	HCC44	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.23347814312210735	[458]	[786,244,615,211]	-4	hSpCas9	negative selection	6759631
73332234	73332257	15	-	27260156	HCC44	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.27854440764249777	[493]	[666,525,636,881]	4	hSpCas9	negative selection	6759632
73343498	73343521	15	-	27260156	HCC44	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.4712672304325274	[777]	[852,1181,1398,1430]	7	hSpCas9	negative selection	6759633
73329684	73329707	15	+	27260156	HCC44	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.031001699141476047	[372]	[453,325,781,173]	0	hSpCas9	negative selection	6823892
73329744	73329767	15	+	27260156	HCC44	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.37265975984400773	[352]	[326,126,481,350]	-5	hSpCas9	negative selection	6823893
73325383	73325406	15	+	27260156	HCC44	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.09039873877304394	[453]	[403,306,620,629]	-1	hSpCas9	negative selection	6823894
73343453	73343476	15	+	27260156	G402	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.29521413470187075	[458]	[614,669,849,603]	3	hSpCas9	negative selection	6880882
73332234	73332257	15	-	27260156	G402	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.3204039121458575	[493]	[659,369,411,504]	-4	hSpCas9	negative selection	6880883
73343498	73343521	15	-	27260156	G402	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.26226453323512156	[777]	[939,1493,1014,1094]	3	hSpCas9	negative selection	6880884
73329684	73329707	15	+	27260156	G402	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.6485203891840086	[372]	[248,402,327,185]	-7	hSpCas9	negative selection	6945143
73329744	73329767	15	+	27260156	G402	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.4798215192376152	[352]	[202,282,62,85]	-9	hSpCas9	negative selection	6945144
73325383	73325406	15	+	27260156	G402	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	0.13156756773649714	[453]	[886,654,650,290]	1	hSpCas9	negative selection	6945145
73343453	73343476	15	+	27260156	L33	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.022512368259600957	[458]	[411,169,371,390]	0	hSpCas9	negative selection	7002133
73332234	73332257	15	-	27260156	L33	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.11856801823958411	[493]	[576,191,273,660]	2	hSpCas9	negative selection	7002134
73343498	73343521	15	-	27260156	L33	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.0817297508393886	[777]	[942,385,523,573]	1	hSpCas9	negative selection	7002135
73329684	73329707	15	+	27260156	L33	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.07543866738925276	[372]	[373,179,224,400]	1	hSpCas9	negative selection	7066394
73329744	73329767	15	+	27260156	L33	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.9171096276357338	[352]	[214,62,139,155]	-9	hSpCas9	negative selection	7066395
73325383	73325406	15	+	27260156	L33	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.09692665289831934	[453]	[451,140,264,478]	-2	hSpCas9	negative selection	7066396
73343453	73343476	15	+	27260156	K562	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.222332822334243	[458]	[443,147,466,334]	-3	hSpCas9	negative selection	7123384
73332234	73332257	15	-	27260156	K562	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.1356780859558654	[493]	[485,611,232,587]	1	hSpCas9	negative selection	7123385
73343498	73343521	15	-	27260156	K562	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.2273959923057931	[777]	[1104,693,838,630]	3	hSpCas9	negative selection	7123386
73329684	73329707	15	+	27260156	K562	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.1806293103918	[372]	[289,280,586,333]	2	hSpCas9	negative selection	7187645
73329744	73329767	15	+	27260156	K562	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.1150284302538025	[352]	[196,103,133,144]	-8	hSpCas9	negative selection	7187646
73325383	73325406	15	+	27260156	K562	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.023309952847873606	[453]	[438,335,352,449]	0	hSpCas9	negative selection	7187647
73343453	73343476	15	+	27260156	HT29	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.1210902521796107	[458]	[520,569,602,376]	-2	hSpCas9	negative selection	7244635
73332234	73332257	15	-	27260156	HT29	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.03272204720198453	[493]	[404,718,672,548]	0	hSpCas9	negative selection	7244636
73343498	73343521	15	-	27260156	HT29	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.07195398229694572	[777]	[1128,1069,944,858]	1	hSpCas9	negative selection	7244637
73329684	73329707	15	+	27260156	HT29	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.20680649839807635	[372]	[673,658,456,344]	4	hSpCas9	negative selection	7308896
73329744	73329767	15	+	27260156	HT29	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.7352435684855869	[352]	[278,330,239,194]	-8	hSpCas9	negative selection	7308897
73325383	73325406	15	+	27260156	HT29	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.11463831562263474	[453]	[598,358,631,446]	-2	hSpCas9	negative selection	7308898
73343453	73343476	15	+	27260156	MHHES1	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.024911909690459685	[458]	[460,592,515,463]	0	hSpCas9	negative selection	7365886
73332234	73332257	15	-	27260156	MHHES1	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.18380730876814122	[493]	[755,849,506,473]	3	hSpCas9	negative selection	7365887
73343498	73343521	15	-	27260156	MHHES1	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.1330481099809866	[777]	[1082,817,795,570]	-2	hSpCas9	negative selection	7365888
73329684	73329707	15	+	27260156	MHHES1	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.3969947468866512	[372]	[497,351,252,214]	-6	hSpCas9	negative selection	7430147
73329744	73329767	15	+	27260156	MHHES1	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.0293409972987158	[352]	[186,204,300,103]	-9	hSpCas9	negative selection	7430148
73325383	73325406	15	+	27260156	MHHES1	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.006682922376027092	[453]	[644,460,652,321]	0	hSpCas9	negative selection	7430149
73343453	73343476	15	+	27260156	MEWO	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.30758364000956867	[458]	[683,497,441]	6	hSpCas9	negative selection	7487137
73332234	73332257	15	-	27260156	MEWO	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.05864728541344928	[493]	[548,486,420]	1	hSpCas9	negative selection	7487138
73343498	73343521	15	-	27260156	MEWO	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.131569190743968	[777]	[906,830,674]	3	hSpCas9	negative selection	7487139
73329684	73329707	15	+	27260156	MEWO	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.024972363091641026	[372]	[301,316,435]	0	hSpCas9	negative selection	7551398
73329744	73329767	15	+	27260156	MEWO	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.8259262431898304	[352]	[283,143,149]	-9	hSpCas9	negative selection	7551399
73325383	73325406	15	+	27260156	MEWO	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.1810597052110257	[453]	[435,322,376]	-4	hSpCas9	negative selection	7551400
73343453	73343476	15	+	27260156	LNCAPCLONEFGC	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.13428352703675114	[458]	[440,385,563,454]	2	hSpCas9	negative selection	7608388
73332234	73332257	15	-	27260156	LNCAPCLONEFGC	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.08254818695358342	[493]	[421,422,625,450]	1	hSpCas9	negative selection	7608389
73343498	73343521	15	-	27260156	LNCAPCLONEFGC	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.19443604157641547	[777]	[738,709,1123,706]	3	hSpCas9	negative selection	7608390
73329684	73329707	15	+	27260156	LNCAPCLONEFGC	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.3125668647093654	[372]	[217,242,392,254]	-5	hSpCas9	negative selection	7672649
73329744	73329767	15	+	27260156	LNCAPCLONEFGC	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.1164572159208046	[352]	[121,92,248,144]	-9	hSpCas9	negative selection	7672650
73325383	73325406	15	+	27260156	LNCAPCLONEFGC	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.2029529479557596	[453]	[357,298,486,307]	-3	hSpCas9	negative selection	7672651
73343453	73343476	15	+	27260156	PANC0327	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.23037310449716633	[458]	[593,535,342,441]	3	hSpCas9	negative selection	7729639
73332234	73332257	15	-	27260156	PANC0327	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.39679338621709564	[493]	[593,527,349,845]	6	hSpCas9	negative selection	7729640
73343498	73343521	15	-	27260156	PANC0327	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.4649563887748964	[777]	[870,1029,1058,838]	7	hSpCas9	negative selection	7729641
73329684	73329707	15	+	27260156	PANC0327	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.10009185040841159	[372]	[281,427,324,369]	1	hSpCas9	negative selection	7793900
73329744	73329767	15	+	27260156	PANC0327	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.7654539641996669	[352]	[196,120,190,237]	-8	hSpCas9	negative selection	7793901
73325383	73325406	15	+	27260156	PANC0327	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	0.13057473115521784	[453]	[428,263,611,482]	2	hSpCas9	negative selection	7793902
73343453	73343476	15	+	27260156	NCIH2009	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.16148856848065465	[458]	[663,467,606]	-2	hSpCas9	negative selection	7850890
73332234	73332257	15	-	27260156	NCIH2009	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.41390632423444734	[493]	[747,1037,934]	6	hSpCas9	negative selection	7850891
73343498	73343521	15	-	27260156	NCIH2009	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.1871436397072106	[777]	[1090,882,1713]	2	hSpCas9	negative selection	7850892
73329684	73329707	15	+	27260156	NCIH2009	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.06994751835090146	[372]	[667,357,498]	-1	hSpCas9	negative selection	7915151
73329744	73329767	15	+	27260156	NCIH2009	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.9861585549934	[352]	[403,256,115]	-8	hSpCas9	negative selection	7915152
73325383	73325406	15	+	27260156	NCIH2009	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.2789001951966635	[453]	[860,433,340]	-4	hSpCas9	negative selection	7915153
73343453	73343476	15	+	27260156	NCIH1373	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.24790940708052492	[458]	[678,497,556,193]	2	hSpCas9	negative selection	7972141
73332234	73332257	15	-	27260156	NCIH1373	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	1.1435941168517432	[493]	[975,492,549,796]	9	hSpCas9	negative selection	7972142
73343498	73343521	15	-	27260156	NCIH1373	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.21163669063577217	[777]	[810,309,950,263]	-2	hSpCas9	negative selection	7972143
73329684	73329707	15	+	27260156	NCIH1373	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.5578399236445211	[372]	[392,169,300,78]	-5	hSpCas9	negative selection	8036402
73329744	73329767	15	+	27260156	NCIH1373	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.0106252830231055	[352]	[266,259,139,30]	-7	hSpCas9	negative selection	8036403
73325383	73325406	15	+	27260156	NCIH1373	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.42468690495042927	[453]	[572,299,381,76]	-4	hSpCas9	negative selection	8036404
73343453	73343476	15	+	27260156	PATU8902	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.04349658360995077	[458]	[642,522,527,1011]	0	hSpCas9	negative selection	8093392
73332234	73332257	15	-	27260156	PATU8902	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.18531965588910293	[493]	[870,764,635,901]	1	hSpCas9	negative selection	8093393
73343498	73343521	15	-	27260156	PATU8902	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.3736914388832573	[777]	[770,814,905,827]	-4	hSpCas9	negative selection	8093394
73329684	73329707	15	+	27260156	PATU8902	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.9894062301233759	[372]	[424,193,234,185]	-7	hSpCas9	negative selection	8157653
73329744	73329767	15	+	27260156	PATU8902	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.6817735778737006	[352]	[165,451,185,472]	-6	hSpCas9	negative selection	8157654
73325383	73325406	15	+	27260156	PATU8902	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	0.037766856521446075	[453]	[334,927,571,798]	0	hSpCas9	negative selection	8157655
73343453	73343476	15	+	27260156	PANC1	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.07684356966352258	[458]	[331,406,475,437]	1	hSpCas9	negative selection	8214643
73332234	73332257	15	-	27260156	PANC1	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.09950217445389084	[493]	[328,456,339,454]	-2	hSpCas9	negative selection	8214644
73343498	73343521	15	-	27260156	PANC1	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.012074677769709052	[777]	[628,748,718,575]	0	hSpCas9	negative selection	8214645
73329684	73329707	15	+	27260156	PANC1	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.49299785232807997	[372]	[156,335,226,212]	-6	hSpCas9	negative selection	8278904
73329744	73329767	15	+	27260156	PANC1	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.4325401333980093	[352]	[149,397,227,165]	-6	hSpCas9	negative selection	8278905
73325383	73325406	15	+	27260156	PANC1	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.010555402536015494	[453]	[196,553,542,301]	0	hSpCas9	negative selection	8278906
73343453	73343476	15	+	27260156	PANC0813	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.27408430299541076	[458]	[435,479,939,727]	4	hSpCas9	negative selection	8335894
73332234	73332257	15	-	27260156	PANC0813	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.3567517558020796	[493]	[663,683,866,748]	6	hSpCas9	negative selection	8335895
73343498	73343521	15	-	27260156	PANC0813	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.06284813163618397	[777]	[905,954,938,1008]	1	hSpCas9	negative selection	8335896
73329684	73329707	15	+	27260156	PANC0813	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.1966402470253203	[372]	[389,459,418,266]	-3	hSpCas9	negative selection	8400155
73329744	73329767	15	+	27260156	PANC0813	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.8135393734694094	[352]	[226,137,237,333]	-8	hSpCas9	negative selection	8400156
73325383	73325406	15	+	27260156	PANC0813	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.055326568475535055	[453]	[505,571,612,368]	-1	hSpCas9	negative selection	8400157
73343453	73343476	15	+	27260156	RDES	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.01447083570437432	[458]	[463,538,495,646]	0	hSpCas9	negative selection	8457145
73332234	73332257	15	-	27260156	RDES	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.03972286213544606	[493]	[441,557,526,713]	0	hSpCas9	negative selection	8457146
73343498	73343521	15	-	27260156	RDES	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.28216351632697495	[777]	[717,601,687,959]	-5	hSpCas9	negative selection	8457147
73329684	73329707	15	+	27260156	RDES	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.3769075229269843	[372]	[240,313,322,476]	-6	hSpCas9	negative selection	8521406
73329744	73329767	15	+	27260156	RDES	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.8657348222064227	[352]	[136,244,272,252]	-8	hSpCas9	negative selection	8521407
73325383	73325406	15	+	27260156	RDES	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.05622338520867464	[453]	[387,451,603,597]	-1	hSpCas9	negative selection	8521408
73343453	73343476	15	+	27260156	PC3	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.13352921632965203	[458]	[291,401,1023,547]	3	hSpCas9	negative selection	8578396
73332234	73332257	15	-	27260156	PC3	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.16718162460056624	[493]	[391,580,740,579]	4	hSpCas9	negative selection	8578397
73343498	73343521	15	-	27260156	PC3	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.17979084024562797	[777]	[608,940,1208,903]	4	hSpCas9	negative selection	8578398
73329684	73329707	15	+	27260156	PC3	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.1157309549064523	[372]	[257,427,630,404]	2	hSpCas9	negative selection	8642657
73329744	73329767	15	+	27260156	PC3	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.045234579917971	[352]	[82,143,373,187]	-9	hSpCas9	negative selection	8642658
73325383	73325406	15	+	27260156	PC3	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.5478472908681756	[453]	[188,393,468,263]	-8	hSpCas9	negative selection	8642659
73343453	73343476	15	+	27260156	PATU8988T	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.23264901607624328	[458]	[353,283,577,273]	-4	hSpCas9	negative selection	8699647
73332234	73332257	15	-	27260156	PATU8988T	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.14548534173277244	[493]	[368,655,621,470]	2	hSpCas9	negative selection	8699648
73343498	73343521	15	-	27260156	PATU8988T	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.1469863734026834	[777]	[360,909,754,712]	-3	hSpCas9	negative selection	8699649
73329684	73329707	15	+	27260156	PATU8988T	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.5085221277797083	[372]	[608,650,243,567]	8	hSpCas9	negative selection	8763908
73329744	73329767	15	+	27260156	PATU8988T	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	0.008195835344900426	[352]	[500,186,509,140]	0	hSpCas9	negative selection	8763909
73325383	73325406	15	+	27260156	PATU8988T	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.2511498734118431	[453]	[385,434,268,393]	-4	hSpCas9	negative selection	8763910
73343453	73343476	15	+	27260156	T47D	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.2188413313366235	[458]	[689,563,627,611]	4	hSpCas9	negative selection	8820898
73332234	73332257	15	-	27260156	T47D	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.08519700455199834	[493]	[547,660,496,736]	1	hSpCas9	negative selection	8820899
73343498	73343521	15	-	27260156	T47D	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.0331743338467988	[777]	[967,858,776,944]	0	hSpCas9	negative selection	8820900
73329684	73329707	15	+	27260156	T47D	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.006549332369398642	[372]	[409,437,486,408]	0	hSpCas9	negative selection	8885159
73329744	73329767	15	+	27260156	T47D	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.6932005573307474	[352]	[224,333,199,251]	-8	hSpCas9	negative selection	8885160
73325383	73325406	15	+	27260156	T47D	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.30816288486360643	[453]	[368,432,396,511]	-6	hSpCas9	negative selection	8885161
73343453	73343476	15	+	27260156	SU8686	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	0.09966321321702357	[458]	[385,330,521,789]	1	hSpCas9	negative selection	8942149
73332234	73332257	15	-	27260156	SU8686	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.29584986752039016	[493]	[558,575,559,733]	5	hSpCas9	negative selection	8942150
73343498	73343521	15	-	27260156	SU8686	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	0.09533461526651998	[777]	[685,738,886,1041]	1	hSpCas9	negative selection	8942151
73329684	73329707	15	+	27260156	SU8686	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.13929069063907112	[372]	[308,235,340,496]	-2	hSpCas9	negative selection	9006410
73329744	73329767	15	+	27260156	SU8686	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.0437272393571353	[352]	[214,164,195,83]	-8	hSpCas9	negative selection	9006411
73325383	73325406	15	+	27260156	SU8686	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.13779065679108266	[453]	[378,429,479,334]	-2	hSpCas9	negative selection	9006412
73343453	73343476	15	+	27260156	SKES1	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.13503432164756005	[458]	[482,491,350,362]	-3	hSpCas9	negative selection	9063400
73332234	73332257	15	-	27260156	SKES1	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.09221518684421857	[493]	[446,527,427,448]	-2	hSpCas9	negative selection	9063401
73343498	73343521	15	-	27260156	SKES1	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.1354472194729761	[777]	[780,703,673,673]	-3	hSpCas9	negative selection	9063402
73329684	73329707	15	+	27260156	SKES1	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.2478991600576788	[372]	[372,289,269,321]	-5	hSpCas9	negative selection	9127661
73329744	73329767	15	+	27260156	SKES1	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-1.0326985215892335	[352]	[209,164,191,128]	-9	hSpCas9	negative selection	9127662
73325383	73325406	15	+	27260156	SKES1	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.1933876380787185	[453]	[370,476,425,320]	-4	hSpCas9	negative selection	9127663
73343453	73343476	15	+	27260156	TOV112D	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.04319622749532436	[458]	[366,633,396,425]	-1	hSpCas9	negative selection	9184651
73332234	73332257	15	-	27260156	TOV112D	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.03308023410209273	[493]	[522,961,358,217]	0	hSpCas9	negative selection	9184652
73343498	73343521	15	-	27260156	TOV112D	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.12404483690642587	[777]	[881,887,557,590]	-2	hSpCas9	negative selection	9184653
73329684	73329707	15	+	27260156	TOV112D	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.128147202452365	[372]	[257,401,209,499]	-2	hSpCas9	negative selection	9248912
73329744	73329767	15	+	27260156	TOV112D	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.7437248296637069	[352]	[74,287,108,374]	-9	hSpCas9	negative selection	9248913
73325383	73325406	15	+	27260156	TOV112D	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.06621786430020618	[453]	[577,594,392,227]	-1	hSpCas9	negative selection	9248914
73343453	73343476	15	+	27260156	TC71	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.28420058465309966	[458]	[400,422,365,428]	-6	hSpCas9	negative selection	9305902
73332234	73332257	15	-	27260156	TC71	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	0.0336295969132035	[493]	[480,593,552,540]	0	hSpCas9	negative selection	9305903
73343498	73343521	15	-	27260156	TC71	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.06371807729301993	[777]	[753,856,834,741]	-2	hSpCas9	negative selection	9305904
73329684	73329707	15	+	27260156	TC71	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.2334903476920846	[372]	[367,386,267,338]	-6	hSpCas9	negative selection	9370163
73329744	73329767	15	+	27260156	TC71	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.8379429869088455	[352]	[264,167,219,190]	-9	hSpCas9	negative selection	9370164
73325383	73325406	15	+	27260156	TC71	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.17148740635656104	[453]	[383,467,425,452]	-4	hSpCas9	negative selection	9370165
73343453	73343476	15	+	27260156	TC32	viability	TCGTGAAGCGGACAATGCGCAGG	HCN4	ENSG00000138622	-0.01023080471548525	[458]	[367,239,554,639]	0	hSpCas9	negative selection	9427153
73332234	73332257	15	-	27260156	TC32	viability	GTGCGCATCGTGAACCTCATCGG	HCN4	ENSG00000138622	-0.021344609078205942	[493]	[581,256,538,500]	0	hSpCas9	negative selection	9427154
73343498	73343521	15	-	27260156	TC32	viability	TGTGGAGACACGCATCGACTCGG	HCN4	ENSG00000138622	-0.25261672411153985	[777]	[494,470,873,697]	-4	hSpCas9	negative selection	9427155
73329684	73329707	15	+	27260156	TC32	viability	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.054720312134867166	[372]	[373,251,353,381]	-1	hSpCas9	negative selection	9491414
73329744	73329767	15	+	27260156	TC32	viability	CATGGCCTTGAAGAGCGCGTAGG	HCN4	ENSG00000138622	-0.9880749153520669	[352]	[224,68,215,188]	-9	hSpCas9	negative selection	9491415
73325383	73325406	15	+	27260156	TC32	viability	ATGCGCTGCCGGGTGTCGGGCGG	HCN4	ENSG00000138622	-0.019461180189724793	[453]	[248,459,415,544]	0	hSpCas9	negative selection	9491416
73324976	73324999	15	-	27869803	HPAFII	viability after 27 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.6809293161425158	[198]	[320,39,NaN]	5	hSpCas9	negative selection	9554634
73325432	73325455	15	-	27869803	HPAFII	viability after 27 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.21538276535843937	[356]	[122,296,NaN]	1	hSpCas9	negative selection	9554635
73329684	73329707	15	+	27869803	HPAFII	viability after 27 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	0.006686999368210322	[299]	[134,177,NaN]	0	hSpCas9	negative selection	9554636
73332239	73332262	15	+	27869803	HPAFII	viability after 27 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-0.4519276199646444	[315]	[103,135,NaN]	-3	hSpCas9	negative selection	9554637
73343459	73343482	15	+	27869803	HPAFII	viability after 27 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.4648361016975704	[108]	[119,189,NaN]	9	hSpCas9	negative selection	9554638
73367881	73367904	15	-	27869803	HPAFII	viability after 27 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.5992545882901904	[112]	[53,119,NaN]	5	hSpCas9	negative selection	9554639
73324976	73324999	15	-	27869803	HPAFII	viability after 15 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.02450705187612645	[198]	[412,95,NaN]	0	hSpCas9	negative selection	9637083
73325432	73325455	15	-	27869803	HPAFII	viability after 15 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	-0.36647758153679544	[356]	[222,343,NaN]	-4	hSpCas9	negative selection	9637084
73329684	73329707	15	+	27869803	HPAFII	viability after 15 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.46101287631228016	[299]	[195,257,NaN]	-5	hSpCas9	negative selection	9637085
73332239	73332262	15	+	27869803	HPAFII	viability after 15 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.06885164481851375	[315]	[518,254,NaN]	0	hSpCas9	negative selection	9637086
73343459	73343482	15	+	27869803	HPAFII	viability after 15 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	-0.31448180699425055	[108]	[108,84,NaN]	-4	hSpCas9	negative selection	9637087
73367881	73367904	15	-	27869803	HPAFII	viability after 15 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.39285445605948954	[112]	[36,126,NaN]	-4	hSpCas9	negative selection	9637088
73324976	73324999	15	-	27869803	ASPC1	viability after 36 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-0.06215129929222929	[566]	[142,233,184]	0	hSpCas9	negative selection	9719532
73325432	73325455	15	-	27869803	ASPC1	viability after 36 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.4669269695942914	[466]	[482,188,70]	5	hSpCas9	negative selection	9719533
73329684	73329707	15	+	27869803	ASPC1	viability after 36 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.46383383364431385	[806]	[228,213,176]	-5	hSpCas9	negative selection	9719534
73332239	73332262	15	+	27869803	ASPC1	viability after 36 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.4609705925869818	[636]	[544,323,120]	4	hSpCas9	negative selection	9719535
73343459	73343482	15	+	27869803	ASPC1	viability after 36 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.141716882212084	[305]	[168,571,12]	9	hSpCas9	negative selection	9719536
73367881	73367904	15	-	27869803	ASPC1	viability after 36 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	1.2485700601972591	[183]	[279,0,181]	9	hSpCas9	negative selection	9719537
73324976	73324999	15	-	27869803	PATU8988S	viability after 35 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	-0.7783377658506425	[397]	[74,111,NaN]	-6	hSpCas9	negative selection	9801981
73325432	73325455	15	-	27869803	PATU8988S	viability after 35 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	-0.2433231256267957	[403]	[118,155,NaN]	-3	hSpCas9	negative selection	9801982
73329684	73329707	15	+	27869803	PATU8988S	viability after 35 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.06319657408395629	[635]	[319,169,NaN]	0	hSpCas9	negative selection	9801983
73332239	73332262	15	+	27869803	PATU8988S	viability after 35 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.938381875831723	[539]	[540,291,NaN]	8	hSpCas9	negative selection	9801984
73343459	73343482	15	+	27869803	PATU8988S	viability after 35 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	-1.0915217415620984	[197]	[2,71,NaN]	-7	hSpCas9	negative selection	9801985
73367881	73367904	15	-	27869803	PATU8988S	viability after 35 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.8432909199146124	[306]	[31,105,NaN]	-7	hSpCas9	negative selection	9801986
73324976	73324999	15	-	27869803	PATU8988S	viability after 31 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.05854203807463848	[397]	[126,213,NaN]	0	hSpCas9	negative selection	9884430
73325432	73325455	15	-	27869803	PATU8988S	viability after 31 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	-0.1431750686253106	[403]	[111,188,NaN]	-2	hSpCas9	negative selection	9884431
73329684	73329707	15	+	27869803	PATU8988S	viability after 31 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.08363391602785786	[635]	[226,254,NaN]	-1	hSpCas9	negative selection	9884432
73332239	73332262	15	+	27869803	PATU8988S	viability after 31 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	0.824457480084158	[539]	[507,219,NaN]	8	hSpCas9	negative selection	9884433
73343459	73343482	15	+	27869803	PATU8988S	viability after 31 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	0.1797379144377136	[197]	[22,173,NaN]	2	hSpCas9	negative selection	9884434
73367881	73367904	15	-	27869803	PATU8988S	viability after 31 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-1.2121582481352726	[306]	[36,72,NaN]	-8	hSpCas9	negative selection	9884435
73324976	73324999	15	-	27869803	HPAFII	viability after 35 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	1.2218352797067722	[198]	[424,20,NaN]	7	hSpCas9	negative selection	9966879
73325432	73325455	15	-	27869803	HPAFII	viability after 35 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.44820315367090113	[356]	[104,405,NaN]	3	hSpCas9	negative selection	9966880
73329684	73329707	15	+	27869803	HPAFII	viability after 35 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.0983490163530076	[299]	[107,179,NaN]	0	hSpCas9	negative selection	9966881
73332239	73332262	15	+	27869803	HPAFII	viability after 35 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-0.6754430033279886	[315]	[78,123,NaN]	-4	hSpCas9	negative selection	9966882
73343459	73343482	15	+	27869803	HPAFII	viability after 35 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.8664304009855095	[108]	[21,402,NaN]	9	hSpCas9	negative selection	9966883
73367881	73367904	15	-	27869803	HPAFII	viability after 35 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.05830781237236371	[112]	[12,111,NaN]	0	hSpCas9	negative selection	9966884
73324976	73324999	15	-	27869803	HPAFII	viability after 31 days	GGGCAACAAGGAGACCAAGCTGG	HCN4	ENSG00000138622	0.8084564543665262	[198]	[353,22,NaN]	6	hSpCas9	negative selection	10049328
73325432	73325455	15	-	27869803	HPAFII	viability after 31 days	CCGGCCTCAGTACAAGCAGGTGG	HCN4	ENSG00000138622	0.4080983536477053	[356]	[83,463,NaN]	3	hSpCas9	negative selection	10049329
73329684	73329707	15	+	27869803	HPAFII	viability after 31 days	CCAGACGTCGGACATGCCCACGG	HCN4	ENSG00000138622	-0.26623808264328874	[299]	[83,200,NaN]	-2	hSpCas9	negative selection	10049330
73332239	73332262	15	+	27869803	HPAFII	viability after 31 days	GAGGTTCACGATGCGCACCACGG	HCN4	ENSG00000138622	-1.545766683915707	[315]	[54,66,NaN]	-7	hSpCas9	negative selection	10049331
73343459	73343482	15	+	27869803	HPAFII	viability after 31 days	AGCGGACAATGCGCAGGGCCCGG	HCN4	ENSG00000138622	1.089376722923954	[108]	[77,186,NaN]	7	hSpCas9	negative selection	10049332
73367881	73367904	15	-	27869803	HPAFII	viability after 31 days	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.38051337489070625	[112]	[27,141,NaN]	2	hSpCas9	negative selection	10049333
73368171	73368194	15	-	28162770	P31FUJ	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	-1.4192153286452602	[65]	[28]	-7	hSpCas9	negative selection	10167819
73325287	73325310	15	+	28162770	P31FUJ	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.23790311704909772	[590]	[818]	2	hSpCas9	negative selection	10167820
73367881	73367904	15	-	28162770	P31FUJ	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.5129335993795596	[327]	[549]	6	hSpCas9	negative selection	10167821
73367697	73367720	15	-	28162770	P31FUJ	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.672334265613971	[296]	[218]	-5	hSpCas9	negative selection	10167822
73367550	73367573	15	-	28162770	P31FUJ	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.07097854376272425	[191]	[236]	0	hSpCas9	negative selection	10167823
73343709	73343732	15	-	28162770	P31FUJ	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.4926594176333771	[276]	[457]	5	hSpCas9	negative selection	10167824
73343495	73343518	15	-	28162770	P31FUJ	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-0.6478397036932224	[151]	[113]	-5	hSpCas9	negative selection	10167825
73343477	73343500	15	-	28162770	P31FUJ	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.12045222466688932	[327]	[418]	1	hSpCas9	negative selection	10167826
73332130	73332153	15	-	28162770	P31FUJ	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	0.014358122071011323	[197]	[234]	0	hSpCas9	negative selection	10167827
73325297	73325320	15	-	28162770	P31FUJ	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.3307578195745533	[248]	[367]	3	hSpCas9	negative selection	10167828
73368171	73368194	15	-	28162770	TF1	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10337185
73325287	73325310	15	+	28162770	TF1	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	NaN	[NaN]	[331]	1	hSpCas9	negative selection	10337186
73367881	73367904	15	-	28162770	TF1	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10337187
73367697	73367720	15	-	28162770	TF1	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10337188
73367550	73367573	15	-	28162770	TF1	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	NaN	[NaN]	[172]	1	hSpCas9	negative selection	10337189
73343709	73343732	15	-	28162770	TF1	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	NaN	[NaN]	[328]	1	hSpCas9	negative selection	10337190
73343495	73343518	15	-	28162770	TF1	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10337191
73343477	73343500	15	-	28162770	TF1	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10337192
73332130	73332153	15	-	28162770	TF1	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	NaN	[NaN]	[201]	1	hSpCas9	negative selection	10337193
73325297	73325320	15	-	28162770	TF1	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	NaN	[NaN]	[259]	1	hSpCas9	negative selection	10337194
73368171	73368194	15	-	28162770	SKM1	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.8218544917527193	[7]	[24]	7	hSpCas9	negative selection	10506551
73325287	73325310	15	+	28162770	SKM1	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	-0.15215029971433647	[131]	[209]	-1	hSpCas9	negative selection	10506552
73367881	73367904	15	-	28162770	SKM1	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.6732579997509186	[93]	[264]	6	hSpCas9	negative selection	10506553
73367697	73367720	15	-	28162770	SKM1	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.41391695938492856	[103]	[137]	-3	hSpCas9	negative selection	10506554
73367550	73367573	15	-	28162770	SKM1	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.07846262842708004	[44]	[83]	0	hSpCas9	negative selection	10506555
73343709	73343732	15	-	28162770	SKM1	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	-0.14392979290936792	[89]	[143]	-1	hSpCas9	negative selection	10506556
73343495	73343518	15	-	28162770	SKM1	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-0.5996092766855575	[35]	[41]	-5	hSpCas9	negative selection	10506557
73343477	73343500	15	-	28162770	SKM1	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.4611703533828643	[82]	[201]	4	hSpCas9	negative selection	10506558
73332130	73332153	15	-	28162770	SKM1	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-0.28696442263253175	[48]	[70]	-2	hSpCas9	negative selection	10506559
73325297	73325320	15	-	28162770	SKM1	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.052467419894135614	[65]	[120]	0	hSpCas9	negative selection	10506560
73368171	73368194	15	-	28162770	SKM1	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.8218544917527193	[7]	[24]	7	hSpCas9	negative selection	10675917
73325287	73325310	15	+	28162770	SKM1	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	-0.15215029971433647	[131]	[209]	-1	hSpCas9	negative selection	10675918
73367881	73367904	15	-	28162770	SKM1	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.6732579997509186	[93]	[264]	6	hSpCas9	negative selection	10675919
73367697	73367720	15	-	28162770	SKM1	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.41391695938492856	[103]	[137]	-3	hSpCas9	negative selection	10675920
73367550	73367573	15	-	28162770	SKM1	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.07846262842708004	[44]	[83]	0	hSpCas9	negative selection	10675921
73343709	73343732	15	-	28162770	SKM1	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	-0.14392979290936792	[89]	[143]	-1	hSpCas9	negative selection	10675922
73343495	73343518	15	-	28162770	SKM1	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-0.5996092766855575	[35]	[41]	-5	hSpCas9	negative selection	10675923
73343477	73343500	15	-	28162770	SKM1	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.4611703533828643	[82]	[201]	4	hSpCas9	negative selection	10675924
73332130	73332153	15	-	28162770	SKM1	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-0.28696442263253175	[48]	[70]	-2	hSpCas9	negative selection	10675925
73325297	73325320	15	-	28162770	SKM1	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.052467419894135614	[65]	[120]	0	hSpCas9	negative selection	10675926
73368171	73368194	15	-	28162770	PL21	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.14355608612295256	[51]	[24]	1	hSpCas9	negative selection	10845283
73325287	73325310	15	+	28162770	PL21	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.8216279912355904	[389]	[299]	7	hSpCas9	negative selection	10845284
73367881	73367904	15	-	28162770	PL21	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.5494738667173343	[291]	[185]	5	hSpCas9	negative selection	10845285
73367697	73367720	15	-	28162770	PL21	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.02825778967245618	[320]	[136]	0	hSpCas9	negative selection	10845286
73367550	73367573	15	-	28162770	PL21	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	-0.297887249460555	[160]	[56]	-2	hSpCas9	negative selection	10845287
73343709	73343732	15	-	28162770	PL21	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.7522959701272346	[340]	[249]	6	hSpCas9	negative selection	10845288
73343495	73343518	15	-	28162770	PL21	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-1.915337602930616	[77]	[8]	-8	hSpCas9	negative selection	10845289
73343477	73343500	15	-	28162770	PL21	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.25260703438345566	[242]	[125]	2	hSpCas9	negative selection	10845290
73332130	73332153	15	-	28162770	PL21	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	0.05127622857483727	[152]	[68]	0	hSpCas9	negative selection	10845291
73325297	73325320	15	-	28162770	PL21	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.6867303747931979	[176]	[123]	6	hSpCas9	negative selection	10845292
73368171	73368194	15	-	28162770	P31FUJ	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	-1.4192153286452602	[65]	[28]	-7	hSpCas9	negative selection	11014649
73325287	73325310	15	+	28162770	P31FUJ	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.23790311704909772	[590]	[818]	2	hSpCas9	negative selection	11014650
73367881	73367904	15	-	28162770	P31FUJ	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.5129335993795596	[327]	[549]	6	hSpCas9	negative selection	11014651
73367697	73367720	15	-	28162770	P31FUJ	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.672334265613971	[296]	[218]	-5	hSpCas9	negative selection	11014652
73367550	73367573	15	-	28162770	P31FUJ	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.07097854376272425	[191]	[236]	0	hSpCas9	negative selection	11014653
73343709	73343732	15	-	28162770	P31FUJ	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.4926594176333771	[276]	[457]	5	hSpCas9	negative selection	11014654
73343495	73343518	15	-	28162770	P31FUJ	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-0.6478397036932224	[151]	[113]	-5	hSpCas9	negative selection	11014655
73343477	73343500	15	-	28162770	P31FUJ	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.12045222466688932	[327]	[418]	1	hSpCas9	negative selection	11014656
73332130	73332153	15	-	28162770	P31FUJ	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	0.014358122071011323	[197]	[234]	0	hSpCas9	negative selection	11014657
73325297	73325320	15	-	28162770	P31FUJ	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.3307578195745533	[248]	[367]	3	hSpCas9	negative selection	11014658
73368171	73368194	15	-	28162770	OCIAML5	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.28038372515965215	[25]	[56]	2	hSpCas9	negative selection	11184015
73325287	73325310	15	+	28162770	OCIAML5	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	-0.3660096082651356	[326]	[457]	-3	hSpCas9	negative selection	11184016
73367881	73367904	15	-	28162770	OCIAML5	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.26281706702035335	[186]	[404]	2	hSpCas9	negative selection	11184017
73367697	73367720	15	-	28162770	OCIAML5	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.08899887415220986	[240]	[408]	0	hSpCas9	negative selection	11184018
73367550	73367573	15	-	28162770	OCIAML5	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	-0.5379579804359339	[110]	[137]	-4	hSpCas9	negative selection	11184019
73343709	73343732	15	-	28162770	OCIAML5	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	-0.22619087687678774	[196]	[303]	-2	hSpCas9	negative selection	11184020
73343495	73343518	15	-	28162770	OCIAML5	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.6022460771482867	[76]	[210]	5	hSpCas9	negative selection	11184021
73343477	73343500	15	-	28162770	OCIAML5	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.1829803762352038	[182]	[374]	1	hSpCas9	negative selection	11184022
73332130	73332153	15	-	28162770	OCIAML5	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	1.5547504216098784	[65]	[349]	9	hSpCas9	negative selection	11184023
73325297	73325320	15	-	28162770	OCIAML5	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	1.001213556497761	[105]	[382]	8	hSpCas9	negative selection	11184024
73368171	73368194	15	-	28162770	EOL1	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.10799391266646574	[117]	[66]	1	hSpCas9	negative selection	11353381
73325287	73325310	15	+	28162770	EOL1	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.7702196251792408	[551]	[495]	6	hSpCas9	negative selection	11353382
73367881	73367904	15	-	28162770	EOL1	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	1.2118631747341861	[598]	[730]	8	hSpCas9	negative selection	11353383
73367697	73367720	15	-	28162770	EOL1	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	0.19085545173166285	[586]	[352]	1	hSpCas9	negative selection	11353384
73367550	73367573	15	-	28162770	EOL1	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	-0.8280146776466901	[309]	[91]	-5	hSpCas9	negative selection	11353385
73343709	73343732	15	-	28162770	EOL1	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.4675928832254499	[581]	[423]	4	hSpCas9	negative selection	11353386
73343495	73343518	15	-	28162770	EOL1	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.7879130795486888	[165]	[150]	7	hSpCas9	negative selection	11353387
73343477	73343500	15	-	28162770	EOL1	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	-1.0162130250547894	[333]	[86]	-6	hSpCas9	negative selection	11353388
73332130	73332153	15	-	28162770	EOL1	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	0.5444050627378767	[176]	[135]	5	hSpCas9	negative selection	11353389
73325297	73325320	15	-	28162770	EOL1	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	-0.5103892851460141	[218]	[80]	-4	hSpCas9	negative selection	11353390
73368171	73368194	15	-	28162770	MOLM13	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.3074247093513327	[75]	[67]	2	hSpCas9	negative selection	11522747
73325287	73325310	15	+	28162770	MOLM13	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.4528611723122471	[578]	[572]	3	hSpCas9	negative selection	11522748
73367881	73367904	15	-	28162770	MOLM13	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.19088203315818075	[497]	[410]	1	hSpCas9	negative selection	11522749
73367697	73367720	15	-	28162770	MOLM13	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	1.4208496258490824	[451]	[874]	9	hSpCas9	negative selection	11522750
73367550	73367573	15	-	28162770	MOLM13	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.4792941448168282	[251]	[253]	3	hSpCas9	negative selection	11522751
73343709	73343732	15	-	28162770	MOLM13	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	-0.34344905443152296	[543]	[309]	-2	hSpCas9	negative selection	11522752
73343495	73343518	15	-	28162770	MOLM13	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.5771184512993371	[177]	[191]	4	hSpCas9	negative selection	11522753
73343477	73343500	15	-	28162770	MOLM13	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.4240145721664954	[433]	[420]	3	hSpCas9	negative selection	11522754
73332130	73332153	15	-	28162770	MOLM13	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	0.5122835009030324	[159]	[164]	4	hSpCas9	negative selection	11522755
73325297	73325320	15	-	28162770	MOLM13	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.7885112789313162	[220]	[275]	6	hSpCas9	negative selection	11522756
73368171	73368194	15	-	28162770	HEL	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.9942112025017344	[57]	[73]	8	hSpCas9	negative selection	11692113
73325287	73325310	15	+	28162770	HEL	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	-0.2052580745545931	[539]	[299]	-1	hSpCas9	negative selection	11692114
73367881	73367904	15	-	28162770	HEL	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	0.6532823262418267	[408]	[411]	5	hSpCas9	negative selection	11692115
73367697	73367720	15	-	28162770	HEL	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	0.592249061546664	[377]	[364]	5	hSpCas9	negative selection	11692116
73367550	73367573	15	-	28162770	HEL	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.26834331721885907	[209]	[161]	2	hSpCas9	negative selection	11692117
73343709	73343732	15	-	28162770	HEL	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.22770133272151338	[423]	[317]	1	hSpCas9	negative selection	11692118
73343495	73343518	15	-	28162770	HEL	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.5902714121062215	[139]	[134]	5	hSpCas9	negative selection	11692119
73343477	73343500	15	-	28162770	HEL	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	-0.39223730624261793	[333]	[162]	-3	hSpCas9	negative selection	11692120
73332130	73332153	15	-	28162770	HEL	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-0.4990351291278065	[202]	[91]	-3	hSpCas9	negative selection	11692121
73325297	73325320	15	-	28162770	HEL	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.1308397934689241	[230]	[161]	1	hSpCas9	negative selection	11692122
73368171	73368194	15	-	28162770	MV411	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.10993402703284039	[65]	[59]	0	hSpCas9	negative selection	11861479
73325287	73325310	15	+	28162770	MV411	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.3673981748236882	[345]	[375]	3	hSpCas9	negative selection	11861480
73367881	73367904	15	-	28162770	MV411	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.014823499341859891	[372]	[310]	0	hSpCas9	negative selection	11861481
73367697	73367720	15	-	28162770	MV411	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	0.5638274621287076	[260]	[324]	5	hSpCas9	negative selection	11861482
73367550	73367573	15	-	28162770	MV411	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	-0.11101642012970092	[149]	[116]	-1	hSpCas9	negative selection	11861483
73343709	73343732	15	-	28162770	MV411	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.4538884282502018	[311]	[359]	4	hSpCas9	negative selection	11861484
73343495	73343518	15	-	28162770	MV411	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	-0.653998614733635	[98]	[52]	-5	hSpCas9	negative selection	11861485
73343477	73343500	15	-	28162770	MV411	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.7796015332123433	[268]	[388]	7	hSpCas9	negative selection	11861486
73332130	73332153	15	-	28162770	MV411	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-0.29736782346639823	[123]	[84]	-2	hSpCas9	negative selection	11861487
73325297	73325320	15	-	28162770	MV411	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	-0.3563347997131394	[192]	[126]	-3	hSpCas9	negative selection	11861488
73368171	73368194	15	-	28162770	MONOMAC1	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	0.05671974518622935	[25]	[30]	0	hSpCas9	negative selection	12030845
73325287	73325310	15	+	28162770	MONOMAC1	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.674565798542854	[228]	[418]	6	hSpCas9	negative selection	12030846
73367881	73367904	15	-	28162770	MONOMAC1	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	1.1376272357552701	[202]	[511]	8	hSpCas9	negative selection	12030847
73367697	73367720	15	-	28162770	MONOMAC1	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	0.40681996541407306	[176]	[268]	4	hSpCas9	negative selection	12030848
73367550	73367573	15	-	28162770	MONOMAC1	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.6305991060467164	[110]	[196]	6	hSpCas9	negative selection	12030849
73343709	73343732	15	-	28162770	MONOMAC1	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.3440085371313957	[188]	[274]	3	hSpCas9	negative selection	12030850
73343495	73343518	15	-	28162770	MONOMAC1	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.9002603542953614	[42]	[91]	8	hSpCas9	negative selection	12030851
73343477	73343500	15	-	28162770	MONOMAC1	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	1.240206446600723	[136]	[370]	9	hSpCas9	negative selection	12030852
73332130	73332153	15	-	28162770	MONOMAC1	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	1.5558702909756739	[80]	[272]	9	hSpCas9	negative selection	12030853
73325297	73325320	15	-	28162770	MONOMAC1	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	-0.32356925298848527	[130]	[119]	-3	hSpCas9	negative selection	12030854
73368171	73368194	15	-	28162770	OCIAML2	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	-0.32767187140011833	[11]	[52]	-3	hSpCas9	negative selection	12200211
73325287	73325310	15	+	28162770	OCIAML2	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.0026222879819783884	[84]	[471]	0	hSpCas9	negative selection	12200212
73367881	73367904	15	-	28162770	OCIAML2	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	1.076857970060332	[51]	[607]	8	hSpCas9	negative selection	12200213
73367697	73367720	15	-	28162770	OCIAML2	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.542659511514815	[76]	[292]	-4	hSpCas9	negative selection	12200214
73367550	73367573	15	-	28162770	OCIAML2	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.0970546840471593	[27]	[165]	0	hSpCas9	negative selection	12200215
73343709	73343732	15	-	28162770	OCIAML2	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.13779164830298385	[60]	[371]	1	hSpCas9	negative selection	12200216
73343495	73343518	15	-	28162770	OCIAML2	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.46523983733812324	[22]	[175]	4	hSpCas9	negative selection	12200217
73343477	73343500	15	-	28162770	OCIAML2	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	0.3818129863439808	[44]	[324]	3	hSpCas9	negative selection	12200218
73332130	73332153	15	-	28162770	OCIAML2	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-0.09559039389523649	[31]	[165]	-1	hSpCas9	negative selection	12200219
73325297	73325320	15	-	28162770	OCIAML2	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	1.4107256782592197	[18]	[279]	9	hSpCas9	negative selection	12200220
73368171	73368194	15	-	28162770	OCIAML3	viability	GGACGAGGAAGAGGACGCCGAGG	HCN4	ENSG00000138622	1.7279204545631992	[3]	[39]	9	hSpCas9	negative selection	12369577
73325287	73325310	15	+	28162770	OCIAML3	viability	ACACAGCTCACCTCCCGCAGGGG	HCN4	ENSG00000138622	0.023135266146142808	[132]	[407]	0	hSpCas9	negative selection	12369578
73367881	73367904	15	-	28162770	OCIAML3	viability	ATGACTCCGCGGAGGAGCGGCGG	HCN4	ENSG00000138622	-0.01391089477482299	[98]	[295]	0	hSpCas9	negative selection	12369579
73367697	73367720	15	-	28162770	OCIAML3	viability	GGACACCGCTATCAAAGTGGAGG	HCN4	ENSG00000138622	-0.17007008172208626	[100]	[270]	-1	hSpCas9	negative selection	12369580
73367550	73367573	15	-	28162770	OCIAML3	viability	GTTCGGCAGCCAGAAAGCCGTGG	HCN4	ENSG00000138622	0.5715784253938121	[36]	[165]	5	hSpCas9	negative selection	12369581
73343709	73343732	15	-	28162770	OCIAML3	viability	AGGATGAGAACACCACACCCTGG	HCN4	ENSG00000138622	0.36819032696345233	[86]	[338]	3	hSpCas9	negative selection	12369582
73343495	73343518	15	-	28162770	OCIAML3	viability	GGAGACACGCATCGACTCGGAGG	HCN4	ENSG00000138622	0.7785465276331672	[27]	[144]	7	hSpCas9	negative selection	12369583
73343477	73343500	15	-	28162770	OCIAML3	viability	GGAGGTCTACAAGACTGCCCGGG	HCN4	ENSG00000138622	-0.84455110197476	[68]	[115]	-6	hSpCas9	negative selection	12369584
73332130	73332153	15	-	28162770	OCIAML3	viability	GGTGTCCATCAACAACATGGTGG	HCN4	ENSG00000138622	-1.1140146992045494	[37]	[52]	-7	hSpCas9	negative selection	12369585
73325297	73325320	15	-	28162770	OCIAML3	viability	GCTAAGCGAGCCCCTGCGGGAGG	HCN4	ENSG00000138622	0.6690267655096306	[54]	[263]	6	hSpCas9	negative selection	12369586