Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10014
• Symbol:HDAC5
• Description:histone deacetylase 5

DataSource: http://genomecrispr.dkfz.de/#!/results/HDAC5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
44091462	44091485	17	-	26472758	Jiyoye	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	0.48963754169784646	[50]	[53]	3	hSpCas9	negative selection	69764
44087645	44087668	17	-	26472758	Jiyoye	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-1.4559428120737397	[210]	[57]	-7	hSpCas9	negative selection	69765
44091321	44091344	17	+	26472758	Jiyoye	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-3.762749619936439	[17]	[0]	-9	hSpCas9	negative selection	69766
44093175	44093198	17	-	26472758	Jiyoye	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.8050172655221957	[210]	[277]	5	hSpCas9	negative selection	69767
44092199	44092222	17	+	26472758	Jiyoye	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.6864591389847421	[102]	[124]	5	hSpCas9	negative selection	69768
44091709	44091732	17	+	26472758	Jiyoye	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.24602058969129326	[245]	[219]	2	hSpCas9	negative selection	69769
44091350	44091373	17	-	26472758	Jiyoye	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	3.86660700014317	[0]	[10]	9	hSpCas9	negative selection	69770
44088519	44088542	17	-	26472758	Jiyoye	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.2223057859939273	[180]	[116]	-1	hSpCas9	negative selection	69771
44088386	44088409	17	-	26472758	Jiyoye	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.5115120413206091	[39]	[42]	4	hSpCas9	negative selection	69772
44087678	44087701	17	-	26472758	Jiyoye	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.009691788330052686	[262]	[196]	0	hSpCas9	negative selection	69773
44091462	44091485	17	-	26472758	KBM7	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	1.1344067203319346	[399,284]	[562,157]	9	hSpCas9	negative selection	260882
44087645	44087668	17	-	26472758	KBM7	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-0.7246766313443701	[1049,910]	[262,291]	-6	hSpCas9	negative selection	260883
44091321	44091344	17	+	26472758	KBM7	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-1.8984476253792777	[50,35]	[6,3]	-8	hSpCas9	negative selection	260884
44093175	44093198	17	-	26472758	KBM7	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.3765409355198639	[1486,1338]	[869,854]	4	hSpCas9	negative selection	260885
44092199	44092222	17	+	26472758	KBM7	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.18884098303521857	[604,524]	[288,181]	-2	hSpCas9	negative selection	260886
44091709	44091732	17	+	26472758	KBM7	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.3033148853305405	[1221,824]	[670,507]	3	hSpCas9	negative selection	260887
44091350	44091373	17	-	26472758	KBM7	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-0.703848865782188	[46,53]	[9,18]	-5	hSpCas9	negative selection	260888
44088519	44088542	17	-	26472758	KBM7	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.03752767598298873	[715,521]	[240,343]	0	hSpCas9	negative selection	260889
44088386	44088409	17	-	26472758	KBM7	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.30176819627892826	[383,296]	[181,207]	3	hSpCas9	negative selection	260890
44087678	44087701	17	-	26472758	KBM7	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.6364356370066009	[1114,1380]	[412,356]	-5	hSpCas9	negative selection	260891
44091462	44091485	17	-	26472758	Raji	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	-0.01814734671025936	[191]	[43]	0	hSpCas9	negative selection	452000
44087645	44087668	17	-	26472758	Raji	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-1.6401991661666355	[590]	[43]	-8	hSpCas9	negative selection	452001
44091321	44091344	17	+	26472758	Raji	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-2.0625414660687134	[17]	[0]	-8	hSpCas9	negative selection	452002
44093175	44093198	17	-	26472758	Raji	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.02064621339471806	[496]	[116]	0	hSpCas9	negative selection	452003
44092199	44092222	17	+	26472758	Raji	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.3451286693239072	[207]	[37]	-3	hSpCas9	negative selection	452004
44091709	44091732	17	+	26472758	Raji	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.24798186554640023	[380]	[104]	2	hSpCas9	negative selection	452005
44091350	44091373	17	-	26472758	Raji	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-2.937010583984854	[32]	[0]	-9	hSpCas9	negative selection	452006
44088519	44088542	17	-	26472758	Raji	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.549693964802547	[261]	[88]	5	hSpCas9	negative selection	452007
44088386	44088409	17	-	26472758	Raji	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.06007782059524297	[185]	[44]	0	hSpCas9	negative selection	452008
44087678	44087701	17	-	26472758	Raji	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.3581637984027859	[590]	[106]	-3	hSpCas9	negative selection	452009
44091462	44091485	17	-	26472758	K562	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	-0.0801540884764792	[272]	[217]	0	hSpCas9	negative selection	643118
44087645	44087668	17	-	26472758	K562	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-2.4087785088071616	[735]	[116]	-8	hSpCas9	negative selection	643119
44091321	44091344	17	+	26472758	K562	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-4.003508785777138	[18]	[0]	-9	hSpCas9	negative selection	643120
44093175	44093198	17	-	26472758	K562	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.8250160358262009	[992]	[1484]	7	hSpCas9	negative selection	643121
44092199	44092222	17	+	26472758	K562	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.3587223543270516	[472]	[511]	3	hSpCas9	negative selection	643122
44091709	44091732	17	+	26472758	K562	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.23092649133833343	[751]	[744]	1	hSpCas9	negative selection	643123
44091350	44091373	17	-	26472758	K562	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	0.5967204715973282	[46]	[59]	5	hSpCas9	negative selection	643124
44088519	44088542	17	-	26472758	K562	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.09568334805530804	[489]	[441]	0	hSpCas9	negative selection	643125
44088386	44088409	17	-	26472758	K562	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.42247160999215966	[235]	[266]	3	hSpCas9	negative selection	643126
44087678	44087701	17	-	26472758	K562	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.6334719962195193	[984]	[535]	-4	hSpCas9	negative selection	643127
44092256	44092279	17	+	26627737	DLD1	viability	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.5446831158567291	[1041]	[654,379,397]	5	hSpCas9	negative selection	798091
44092440	44092463	17	+	26627737	DLD1	viability	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.2670717705430451	[825]	[266,308,349]	2	hSpCas9	negative selection	798092
44092699	44092722	17	+	26627737	DLD1	viability	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.4836529000603379	[251]	[31,173,124]	5	hSpCas9	negative selection	798093
44093128	44093151	17	-	26627737	DLD1	viability	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.40480784308527606	[443]	[128,218,201]	4	hSpCas9	negative selection	798094
44093745	44093768	17	-	26627737	DLD1	viability	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.4999345678276317	[220]	[91,17,36]	-5	hSpCas9	negative selection	798095
44110758	44110781	17	+	26627737	DLD1	viability	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.19735434533663754	[1143]	[431,409,390]	2	hSpCas9	negative selection	798096
44092256	44092279	17	+	26627737	GBM cells	viability after 5 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	-0.1100192498843221	[485]	[249,232]	-2	hSpCas9	negative selection	880406
44092440	44092463	17	+	26627737	GBM cells	viability after 5 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.5282198162041145	[518]	[174,210]	-7	hSpCas9	negative selection	880407
44092699	44092722	17	+	26627737	GBM cells	viability after 5 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.688017092387067	[124]	[97,117]	8	hSpCas9	negative selection	880408
44093128	44093151	17	-	26627737	GBM cells	viability after 5 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.49238390332388743	[441]	[150,185]	-7	hSpCas9	negative selection	880409
44093745	44093768	17	-	26627737	GBM cells	viability after 5 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.3757085052233202	[149]	[65,57]	-5	hSpCas9	negative selection	880410
44110758	44110781	17	+	26627737	GBM cells	viability after 5 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.2971078640011149	[559]	[346,390]	4	hSpCas9	negative selection	880411
44092256	44092279	17	+	26627737	GBM cells	viability after 13 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	-0.012569700315313459	[485]	[315,216]	0	hSpCas9	negative selection	962721
44092440	44092463	17	+	26627737	GBM cells	viability after 13 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.23210059976130248	[518]	[220,254]	-3	hSpCas9	negative selection	962722
44092699	44092722	17	+	26627737	GBM cells	viability after 13 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.5968334992699333	[124]	[149,63]	7	hSpCas9	negative selection	962723
44093128	44093151	17	-	26627737	GBM cells	viability after 13 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.5586340494265988	[441]	[153,169]	-6	hSpCas9	negative selection	962724
44093745	44093768	17	-	26627737	GBM cells	viability after 13 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.16422308890095705	[149]	[72,105]	2	hSpCas9	negative selection	962725
44110758	44110781	17	+	26627737	GBM cells	viability after 13 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.44376812332077353	[559]	[404,419]	5	hSpCas9	negative selection	962726
44092256	44092279	17	+	26627737	GBM cells	viability after 21 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.029621737851294627	[485]	[280,258]	0	hSpCas9	negative selection	1045036
44092440	44092463	17	+	26627737	GBM cells	viability after 21 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.34472495777630696	[518]	[232,211]	-3	hSpCas9	negative selection	1045037
44092699	44092722	17	+	26627737	GBM cells	viability after 21 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.313999915288919	[124]	[97,71]	3	hSpCas9	negative selection	1045038
44093128	44093151	17	-	26627737	GBM cells	viability after 21 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.16066982978979294	[441]	[218,210]	-1	hSpCas9	negative selection	1045039
44093745	44093768	17	-	26627737	GBM cells	viability after 21 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	1.0739466449455455	[149]	[181,161]	9	hSpCas9	negative selection	1045040
44110758	44110781	17	+	26627737	GBM cells	viability after 21 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.5571955631629033	[559]	[443,450]	5	hSpCas9	negative selection	1045041
44092256	44092279	17	+	26627737	RPE1	viability after 9 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.7768129306254841	[1106]	[612,568]	5	hSpCas9	negative selection	1127351
44092440	44092463	17	+	26627737	RPE1	viability after 9 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.35520178799135027	[1315]	[208,467]	-3	hSpCas9	negative selection	1127352
44092699	44092722	17	+	26627737	RPE1	viability after 9 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.0464881257669798	[282]	[120,262]	6	hSpCas9	negative selection	1127353
44093128	44093151	17	-	26627737	RPE1	viability after 9 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.8813317651965829	[1766]	[267,341]	-6	hSpCas9	negative selection	1127354
44093745	44093768	17	-	26627737	RPE1	viability after 9 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.46228868327959005	[483]	[151,281]	3	hSpCas9	negative selection	1127355
44110758	44110781	17	+	26627737	RPE1	viability after 9 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.3137813857773937	[2946]	[1034,1290]	2	hSpCas9	negative selection	1127356
44092256	44092279	17	+	26627737	RPE1	viability after 12 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.8016733243133156	[1106]	[430,610]	5	hSpCas9	negative selection	1209666
44092440	44092463	17	+	26627737	RPE1	viability after 12 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.19637168706887687	[1315]	[327,287]	-1	hSpCas9	negative selection	1209667
44092699	44092722	17	+	26627737	RPE1	viability after 12 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.1269891395291303	[282]	[82,253]	6	hSpCas9	negative selection	1209668
44093128	44093151	17	-	26627737	RPE1	viability after 12 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-1.1235471140973305	[1766]	[281,149]	-6	hSpCas9	negative selection	1209669
44093745	44093768	17	-	26627737	RPE1	viability after 12 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.025696124486848437	[483]	[127,136]	0	hSpCas9	negative selection	1209670
44110758	44110781	17	+	26627737	RPE1	viability after 12 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.24768471227473032	[2946]	[992,883]	1	hSpCas9	negative selection	1209671
44092256	44092279	17	+	26627737	RPE1	viability after 15 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.88169162003913	[1106]	[577,575]	5	hSpCas9	negative selection	1291981
44092440	44092463	17	+	26627737	RPE1	viability after 15 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.5197114029731429	[1315]	[334,186]	-3	hSpCas9	negative selection	1291982
44092699	44092722	17	+	26627737	RPE1	viability after 15 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.1434785767656401	[282]	[128,222]	6	hSpCas9	negative selection	1291983
44093128	44093151	17	-	26627737	RPE1	viability after 15 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-1.0761397901222376	[1766]	[260,213]	-6	hSpCas9	negative selection	1291984
44093745	44093768	17	-	26627737	RPE1	viability after 15 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	1.2101019027157467	[483]	[414,221]	7	hSpCas9	negative selection	1291985
44110758	44110781	17	+	26627737	RPE1	viability after 15 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.03248411896512149	[2946]	[929,777]	0	hSpCas9	negative selection	1291986
44092256	44092279	17	+	26627737	RPE1	viability after 18 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.7086664758933023	[1106]	[363,620]	4	hSpCas9	negative selection	1374296
44092440	44092463	17	+	26627737	RPE1	viability after 18 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.063789813721847	[1315]	[420,252]	0	hSpCas9	negative selection	1374297
44092699	44092722	17	+	26627737	RPE1	viability after 18 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.903015397709239	[282]	[201,374]	8	hSpCas9	negative selection	1374298
44093128	44093151	17	-	26627737	RPE1	viability after 18 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-1.0770273391674587	[1766]	[226,224]	-6	hSpCas9	negative selection	1374299
44093745	44093768	17	-	26627737	RPE1	viability after 18 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.43779236885956135	[483]	[130,225]	2	hSpCas9	negative selection	1374300
44110758	44110781	17	+	26627737	RPE1	viability after 18 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.31864022083798815	[2946]	[987,995]	2	hSpCas9	negative selection	1374301
44092256	44092279	17	+	26627737	HeLa	viability after 8 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.5681355467147602	[660]	[412,505,361]	5	hSpCas9	negative selection	1456611
44092440	44092463	17	+	26627737	HeLa	viability after 8 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.19135295532119212	[493]	[206,306,215]	1	hSpCas9	negative selection	1456612
44092699	44092722	17	+	26627737	HeLa	viability after 8 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.376737637170907	[201]	[33,135,151]	3	hSpCas9	negative selection	1456613
44093128	44093151	17	-	26627737	HeLa	viability after 8 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.0346366294528439	[373]	[104,218,141]	0	hSpCas9	negative selection	1456614
44093745	44093768	17	-	26627737	HeLa	viability after 8 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.6982634947453266	[238]	[162,0,50]	-6	hSpCas9	negative selection	1456615
44110758	44110781	17	+	26627737	HeLa	viability after 8 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	-0.25343577297135145	[1563]	[809,482,478]	-2	hSpCas9	negative selection	1456616
44092256	44092279	17	+	26627737	HeLa	viability after 12 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.8179319919347674	[660]	[720,364,377]	6	hSpCas9	negative selection	1538926
44092440	44092463	17	+	26627737	HeLa	viability after 12 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.04271370165673544	[493]	[153,202,272]	0	hSpCas9	negative selection	1538927
44092699	44092722	17	+	26627737	HeLa	viability after 12 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.7078287159739365	[201]	[145,63,206]	6	hSpCas9	negative selection	1538928
44093128	44093151	17	-	26627737	HeLa	viability after 12 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.32517016214919037	[373]	[162,89,337]	3	hSpCas9	negative selection	1538929
44093745	44093768	17	-	26627737	HeLa	viability after 12 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.4330660005604592	[238]	[166,8,52]	-4	hSpCas9	negative selection	1538930
44110758	44110781	17	+	26627737	HeLa	viability after 12 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.006377558170048481	[1563]	[663,696,581]	0	hSpCas9	negative selection	1538931
44092256	44092279	17	+	26627737	HeLa	viability after 15 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.168912131926373	[660]	[324,282,298]	1	hSpCas9	negative selection	1621241
44092440	44092463	17	+	26627737	HeLa	viability after 15 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.433792480904339	[493]	[350,262,193]	3	hSpCas9	negative selection	1621242
44092699	44092722	17	+	26627737	HeLa	viability after 15 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.6106371677725522	[201]	[73,145,159]	5	hSpCas9	negative selection	1621243
44093128	44093151	17	-	26627737	HeLa	viability after 15 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.17377549354319477	[373]	[101,231,182]	1	hSpCas9	negative selection	1621244
44093745	44093768	17	-	26627737	HeLa	viability after 15 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.2437254779082746	[238]	[49,113,82]	-2	hSpCas9	negative selection	1621245
44110758	44110781	17	+	26627737	HeLa	viability after 15 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	-0.1719266482790427	[1563]	[324,791,582]	-1	hSpCas9	negative selection	1621246
44092256	44092279	17	+	26627737	HeLa	viability after 18 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.1656489494401191	[660]	[212,238,298]	1	hSpCas9	negative selection	1703556
44092440	44092463	17	+	26627737	HeLa	viability after 18 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.44053074442100637	[493]	[232,223,193]	3	hSpCas9	negative selection	1703557
44092699	44092722	17	+	26627737	HeLa	viability after 18 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.647003273428504	[201]	[50,126,159]	5	hSpCas9	negative selection	1703558
44093128	44093151	17	-	26627737	HeLa	viability after 18 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.16285058354773338	[373]	[65,191,182]	1	hSpCas9	negative selection	1703559
44093745	44093768	17	-	26627737	HeLa	viability after 18 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.2515477632823041	[238]	[32,93,82]	-2	hSpCas9	negative selection	1703560
44110758	44110781	17	+	26627737	HeLa	viability after 18 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	-0.20069040511936698	[1563]	[208,639,582]	-2	hSpCas9	negative selection	1703561
44092256	44092279	17	+	26627737	HCT116	viability after 6 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.9231286753078045	[1565]	[451,474]	5	hSpCas9	negative selection	1785871
44092440	44092463	17	+	26627737	HCT116	viability after 6 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-2.517219816488102	[728]	[39,8]	-8	hSpCas9	negative selection	1785872
44092699	44092722	17	+	26627737	HCT116	viability after 6 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.09410066071866585	[341]	[126,18]	0	hSpCas9	negative selection	1785873
44093128	44093151	17	-	26627737	HCT116	viability after 6 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-1.2313630877285728	[773]	[36,59]	-6	hSpCas9	negative selection	1785874
44093745	44093768	17	-	26627737	HCT116	viability after 6 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.33766768578024825	[739]	[151,58]	-2	hSpCas9	negative selection	1785875
44110758	44110781	17	+	26627737	HCT116	viability after 6 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.30219531616634976	[1992]	[453,348]	1	hSpCas9	negative selection	1785876
44092256	44092279	17	+	26627737	HCT116	viability after 8 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.49303810767102596	[521]	[294,553,363]	5	hSpCas9	negative selection	1868186
44092440	44092463	17	+	26627737	HCT116	viability after 8 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.0556876061216538	[519]	[229,300,294]	0	hSpCas9	negative selection	1868187
44092699	44092722	17	+	26627737	HCT116	viability after 8 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.9375184602990477	[86]	[109,92,72]	8	hSpCas9	negative selection	1868188
44093128	44093151	17	-	26627737	HCT116	viability after 8 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.14860174761457007	[409]	[232,261,117]	-2	hSpCas9	negative selection	1868189
44093745	44093768	17	-	26627737	HCT116	viability after 8 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.7810594001729382	[100]	[137,81,67]	7	hSpCas9	negative selection	1868190
44110758	44110781	17	+	26627737	HCT116	viability after 8 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.06343368133045546	[886]	[557,543,431]	0	hSpCas9	negative selection	1868191
44092256	44092279	17	+	26627737	HCT116	viability after 9 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	-0.6026544055228914	[1565]	[185,345]	-4	hSpCas9	negative selection	1950501
44092440	44092463	17	+	26627737	HCT116	viability after 9 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.33487931043438807	[728]	[174,137]	-2	hSpCas9	negative selection	1950502
44092699	44092722	17	+	26627737	HCT116	viability after 9 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.6714318892238217	[341]	[207,95]	5	hSpCas9	negative selection	1950503
44093128	44093151	17	-	26627737	HCT116	viability after 9 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.7202261040262913	[773]	[206,60]	-5	hSpCas9	negative selection	1950504
44093745	44093768	17	-	26627737	HCT116	viability after 9 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-1.8026514677344911	[739]	[102,19]	-8	hSpCas9	negative selection	1950505
44110758	44110781	17	+	26627737	HCT116	viability after 9 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.14537221751268214	[1992]	[396,739]	1	hSpCas9	negative selection	1950506
44092256	44092279	17	+	26627737	HCT116	viability after 12 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.5228897631369005	[521]	[330,351,503]	5	hSpCas9	negative selection	2032816
44092440	44092463	17	+	26627737	HCT116	viability after 12 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.32629954223586244	[519]	[287,146,210]	-3	hSpCas9	negative selection	2032817
44092699	44092722	17	+	26627737	HCT116	viability after 12 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.0327889868280962	[86]	[122,132,22]	8	hSpCas9	negative selection	2032818
44093128	44093151	17	-	26627737	HCT116	viability after 12 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.2757479885912236	[409]	[85,300,157]	-3	hSpCas9	negative selection	2032819
44093745	44093768	17	-	26627737	HCT116	viability after 12 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	1.1587346968075012	[100]	[144,110,96]	8	hSpCas9	negative selection	2032820
44110758	44110781	17	+	26627737	HCT116	viability after 12 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	-0.07491748530687281	[886]	[406,533,391]	0	hSpCas9	negative selection	2032821
44092256	44092279	17	+	26627737	HCT116	viability after 15 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.5758256497018743	[521]	[334,470,519]	5	hSpCas9	negative selection	2115131
44092440	44092463	17	+	26627737	HCT116	viability after 15 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.5116287869306777	[519]	[278,158,198]	-5	hSpCas9	negative selection	2115132
44092699	44092722	17	+	26627737	HCT116	viability after 15 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.1921791156156507	[86]	[79,115,141]	8	hSpCas9	negative selection	2115133
44093128	44093151	17	-	26627737	HCT116	viability after 15 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.2537674122463087	[409]	[158,250,177]	-3	hSpCas9	negative selection	2115134
44093745	44093768	17	-	26627737	HCT116	viability after 15 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	1.3823637625352263	[100]	[173,179,102]	9	hSpCas9	negative selection	2115135
44110758	44110781	17	+	26627737	HCT116	viability after 15 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.16017123628689123	[886]	[685,478,556]	1	hSpCas9	negative selection	2115136
44092256	44092279	17	+	26627737	HCT116	viability after 18 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.8957224071373941	[521]	[273,434,712]	7	hSpCas9	negative selection	2197446
44092440	44092463	17	+	26627737	HCT116	viability after 18 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.2934016525047637	[519]	[263,132,223]	-3	hSpCas9	negative selection	2197447
44092699	44092722	17	+	26627737	HCT116	viability after 18 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.9100259055512776	[86]	[131,161,180]	9	hSpCas9	negative selection	2197448
44093128	44093151	17	-	26627737	HCT116	viability after 18 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.4302705845258122	[409]	[66,173,200]	-4	hSpCas9	negative selection	2197449
44093745	44093768	17	-	26627737	HCT116	viability after 18 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.5616801440991015	[100]	[7,142,59]	5	hSpCas9	negative selection	2197450
44110758	44110781	17	+	26627737	HCT116	viability after 18 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.3656557447541098	[886]	[613,437,615]	3	hSpCas9	negative selection	2197451
44093820	44093843	17	-	24336569	HL60	viability	GCCCACAGTGGAGGTGAAGCCGG	HDAC5	ENSG00000108840	-0.40167805370614657	[735]	[1178]	-4	hSpCas9	negative selection	2269174
44110716	44110739	17	+	24336569	HL60	viability	TCAAGGCACTTACCTGTCACAGG	HDAC5	ENSG00000108840	0.4468619763459203	[1090]	[3146]	4	hSpCas9	negative selection	2269175
44110728	44110751	17	-	24336569	HL60	viability	CTGCACAGCATCCCTGTGACAGG	HDAC5	ENSG00000108840	-0.30117107479858934	[491]	[844]	-3	hSpCas9	negative selection	2269176
44110740	44110763	17	+	24336569	HL60	viability	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	0.048749660047937515	[486]	[1065]	0	hSpCas9	negative selection	2269177
44110754	44110777	17	+	24336569	HL60	viability	AGTCCGCGGCAGGATTTCCAAGG	HDAC5	ENSG00000108840	0.2023288653716948	[252]	[615]	2	hSpCas9	negative selection	2269178
44110771	44110794	17	-	24336569	HL60	viability	GTCAGGTCGGGAACCATCCTTGG	HDAC5	ENSG00000108840	-0.663441861025442	[844]	[1128]	-6	hSpCas9	negative selection	2269179
44110783	44110806	17	-	24336569	HL60	viability	AGCAGATGGGATGTCAGGTCGGG	HDAC5	ENSG00000108840	-0.3799473424669798	[1029]	[1674]	-3	hSpCas9	negative selection	2269180
44110788	44110811	17	-	24336569	HL60	viability	TTCTCAGCAGATGGGATGTCAGG	HDAC5	ENSG00000108840	1.7366412067976582	[190]	[1346]	9	hSpCas9	negative selection	2269181
44093820	44093843	17	-	24336569	KBM7	viability	GCCCACAGTGGAGGTGAAGCCGG	HDAC5	ENSG00000108840	0.6144745946923664	[528]	[2208]	5	hSpCas9	negative selection	2336351
44110716	44110739	17	+	24336569	KBM7	viability	TCAAGGCACTTACCTGTCACAGG	HDAC5	ENSG00000108840	0.6933498018001758	[630]	[2782]	6	hSpCas9	negative selection	2336352
44110728	44110751	17	-	24336569	KBM7	viability	CTGCACAGCATCCCTGTGACAGG	HDAC5	ENSG00000108840	0.22895990652441345	[411]	[1316]	2	hSpCas9	negative selection	2336353
44110740	44110763	17	+	24336569	KBM7	viability	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	-0.0059808709989037645	[295]	[803]	0	hSpCas9	negative selection	2336354
44110754	44110777	17	+	24336569	KBM7	viability	AGTCCGCGGCAGGATTTCCAAGG	HDAC5	ENSG00000108840	-0.3074314901286066	[445]	[982]	-3	hSpCas9	negative selection	2336355
44110771	44110794	17	-	24336569	KBM7	viability	GTCAGGTCGGGAACCATCCTTGG	HDAC5	ENSG00000108840	-0.2415385252374439	[468]	[1081]	-2	hSpCas9	negative selection	2336356
44110783	44110806	17	-	24336569	KBM7	viability	AGCAGATGGGATGTCAGGTCGGG	HDAC5	ENSG00000108840	-0.32834495867005337	[707]	[1537]	-3	hSpCas9	negative selection	2336357
44110788	44110811	17	-	24336569	KBM7	viability	TTCTCAGCAGATGGGATGTCAGG	HDAC5	ENSG00000108840	0.23898144418008038	[465]	[1499]	2	hSpCas9	negative selection	2336358
44079379	44079402	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGCACTTTGG	HDAC5	ENSG00000108840	-0.9680503266497309	[486,330]	[14,78]	-5	dCas9-VP64	positive selection	2398850
44100544	44100567	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTTGG	HDAC5	ENSG00000108840	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409703
44100473	44100496	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAATCCCAGCACTTTGAG	HDAC5	ENSG00000108840	0.14000166748158183	[525,123]	[99,52]	0	dCas9-VP64	positive selection	2444611
44079379	44079402	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGCACTTTGG	HDAC5	ENSG00000108840	0.18483027177666878	[252,653]	[84,243]	1	dCas9-VP64	positive selection	2494105
44100544	44100567	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTTGG	HDAC5	ENSG00000108840	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504958
44100473	44100496	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAATCCCAGCACTTTGAG	HDAC5	ENSG00000108840	2.3170246663226814	[189,235]	[324,366]	8	dCas9-VP64	positive selection	2539866
44110783	44110806	17	-	27260157	DLD1	viability	AGCAGATGGGATGTCAGGTCGGG	HDAC5	ENSG00000108840	1.0019940378338	[]	[]	9	hSpCas9	negative selection	2576565
44110716	44110739	17	+	27260157	DLD1	viability	TCAAGGCACTTACCTGTCACAGG	HDAC5	ENSG00000108840	-0.568771642814455	[]	[]	-4	hSpCas9	negative selection	2580162
44092251	44092274	17	-	27260157	DLD1	viability	TGTAACAGCGCACCCGGCTCCGG	HDAC5	ENSG00000108840	-0.251239037002646	[]	[]	-2	hSpCas9	negative selection	2580898
44110788	44110811	17	-	27260157	DLD1	viability	TTCTCAGCAGATGGGATGTCAGG	HDAC5	ENSG00000108840	0.245459642779178	[]	[]	4	hSpCas9	negative selection	2583756
44092692	44092715	17	+	27260157	DLD1	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.358093122107273	[]	[]	4	hSpCas9	negative selection	2586587
44110728	44110751	17	-	27260157	DLD1	viability	CTGCACAGCATCCCTGTGACAGG	HDAC5	ENSG00000108840	0.876111936411111	[]	[]	9	hSpCas9	negative selection	2586776
44110740	44110763	17	+	27260157	DLD1	viability	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	0.276160527638274	[]	[]	4	hSpCas9	negative selection	2606182
44110771	44110794	17	-	27260157	DLD1	viability	GTCAGGTCGGGAACCATCCTTGG	HDAC5	ENSG00000108840	-0.668899339129442	[]	[]	-5	hSpCas9	negative selection	2606996
44091464	44091487	17	+	27260157	DLD1	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.708471890278882	[]	[]	-5	hSpCas9	negative selection	2610548
44093820	44093843	17	-	27260157	DLD1	viability	GCCCACAGTGGAGGTGAAGCCGG	HDAC5	ENSG00000108840	0.0154765069218957	[]	[]	0	hSpCas9	negative selection	2611866
44092439	44092462	17	-	27260157	DLD1	viability	CCCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.11016298048911	[]	[]	3	hSpCas9	negative selection	2621258
44110754	44110777	17	+	27260157	DLD1	viability	AGTCCGCGGCAGGATTTCCAAGG	HDAC5	ENSG00000108840	0.346711366345932	[]	[]	4	hSpCas9	negative selection	2624181
44092435	44092458	17	+	27260157	DLD1	viability	CAGTCCCATCCTTGCGACGCAGG	HDAC5	ENSG00000108840	-1.09321905629572	[]	[]	-7	hSpCas9	negative selection	2644488
44092256	44092279	17	+	27260157	DLD1	viability	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.309175677932527	[]	[]	4	hSpCas9	negative selection	2647433
44093118	44093141	17	+	27260157	DLD1	viability	ATGGTTGAGGCCGCCTGGTGTGG	HDAC5	ENSG00000108840	0.0788412092489214	[]	[]	3	hSpCas9	negative selection	2647781
44091769	44091792	17	+	27260157	DLD1	viability	CGTGTAGAGGCTGAACTGGTTGG	HDAC5	ENSG00000108840	0.351641893880745	[]	[]	4	hSpCas9	negative selection	2647783
44091349	44091372	17	-	27260157	DLD1	viability	GCGTGGCACTGGAGGGCGACGGG	HDAC5	ENSG00000108840	-0.0882946997555422	[]	[]	0	hSpCas9	negative selection	2648703
44110783	44110806	17	-	27260157	HT1080	viability	AGCAGATGGGATGTCAGGTCGGG	HDAC5	ENSG00000108840	0.0453776775961036	[]	[]	0	hSpCas9	negative selection	2652695
44110716	44110739	17	+	27260157	HT1080	viability	TCAAGGCACTTACCTGTCACAGG	HDAC5	ENSG00000108840	-0.037805544747654	[]	[]	0	hSpCas9	negative selection	2656292
44092251	44092274	17	-	27260157	HT1080	viability	TGTAACAGCGCACCCGGCTCCGG	HDAC5	ENSG00000108840	0.478087673453112	[]	[]	4	hSpCas9	negative selection	2657028
44110788	44110811	17	-	27260157	HT1080	viability	TTCTCAGCAGATGGGATGTCAGG	HDAC5	ENSG00000108840	0.599935784974025	[]	[]	5	hSpCas9	negative selection	2659886
44092692	44092715	17	+	27260157	HT1080	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.0532622409530048	[]	[]	0	hSpCas9	negative selection	2662717
44110728	44110751	17	-	27260157	HT1080	viability	CTGCACAGCATCCCTGTGACAGG	HDAC5	ENSG00000108840	0.831316370011042	[]	[]	7	hSpCas9	negative selection	2662906
44110740	44110763	17	+	27260157	HT1080	viability	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	0.881565348440269	[]	[]	7	hSpCas9	negative selection	2682312
44110771	44110794	17	-	27260157	HT1080	viability	GTCAGGTCGGGAACCATCCTTGG	HDAC5	ENSG00000108840	0.906368787438964	[]	[]	7	hSpCas9	negative selection	2683126
44091464	44091487	17	+	27260157	HT1080	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-1.04601510394159	[]	[]	-8	hSpCas9	negative selection	2686678
44093820	44093843	17	-	27260157	HT1080	viability	GCCCACAGTGGAGGTGAAGCCGG	HDAC5	ENSG00000108840	0.839031613721108	[]	[]	7	hSpCas9	negative selection	2687996
44092439	44092462	17	-	27260157	HT1080	viability	CCCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.854525406841127	[]	[]	-8	hSpCas9	negative selection	2697388
44110754	44110777	17	+	27260157	HT1080	viability	AGTCCGCGGCAGGATTTCCAAGG	HDAC5	ENSG00000108840	0.942962560431981	[]	[]	7	hSpCas9	negative selection	2700311
44092435	44092458	17	+	27260157	HT1080	viability	CAGTCCCATCCTTGCGACGCAGG	HDAC5	ENSG00000108840	-0.236655385480036	[]	[]	0	hSpCas9	negative selection	2720618
44092256	44092279	17	+	27260157	HT1080	viability	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	1.32283400734743	[]	[]	9	hSpCas9	negative selection	2723563
44093118	44093141	17	+	27260157	HT1080	viability	ATGGTTGAGGCCGCCTGGTGTGG	HDAC5	ENSG00000108840	-0.0242221708398226	[]	[]	0	hSpCas9	negative selection	2723911
44091769	44091792	17	+	27260157	HT1080	viability	CGTGTAGAGGCTGAACTGGTTGG	HDAC5	ENSG00000108840	-0.241752043651305	[]	[]	0	hSpCas9	negative selection	2723913
44091349	44091372	17	-	27260157	HT1080	viability	GCGTGGCACTGGAGGGCGACGGG	HDAC5	ENSG00000108840	0.305280452158601	[]	[]	3	hSpCas9	negative selection	2724833
44110783	44110806	17	-	27260157	MKN45	viability	AGCAGATGGGATGTCAGGTCGGG	HDAC5	ENSG00000108840	-0.690758698798375	[]	[]	-7	hSpCas9	negative selection	2728825
44110716	44110739	17	+	27260157	MKN45	viability	TCAAGGCACTTACCTGTCACAGG	HDAC5	ENSG00000108840	0.268872442568071	[]	[]	5	hSpCas9	negative selection	2732422
44092251	44092274	17	-	27260157	MKN45	viability	TGTAACAGCGCACCCGGCTCCGG	HDAC5	ENSG00000108840	-0.83375615967261	[]	[]	-7	hSpCas9	negative selection	2733158
44110788	44110811	17	-	27260157	MKN45	viability	TTCTCAGCAGATGGGATGTCAGG	HDAC5	ENSG00000108840	0.267083662305964	[]	[]	5	hSpCas9	negative selection	2736016
44092692	44092715	17	+	27260157	MKN45	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.575873189017749	[]	[]	7	hSpCas9	negative selection	2738847
44110728	44110751	17	-	27260157	MKN45	viability	CTGCACAGCATCCCTGTGACAGG	HDAC5	ENSG00000108840	0.209803397236971	[]	[]	5	hSpCas9	negative selection	2739036
44110740	44110763	17	+	27260157	MKN45	viability	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	-0.695779509493211	[]	[]	-7	hSpCas9	negative selection	2758442
44110771	44110794	17	-	27260157	MKN45	viability	GTCAGGTCGGGAACCATCCTTGG	HDAC5	ENSG00000108840	-0.06485374815214	[]	[]	0	hSpCas9	negative selection	2759256
44091464	44091487	17	+	27260157	MKN45	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.161883810152897	[]	[]	0	hSpCas9	negative selection	2762808
44093820	44093843	17	-	27260157	MKN45	viability	GCCCACAGTGGAGGTGAAGCCGG	HDAC5	ENSG00000108840	-0.38110820507055	[]	[]	-1	hSpCas9	negative selection	2764126
44092439	44092462	17	-	27260157	MKN45	viability	CCCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-1.65642152719945	[]	[]	-9	hSpCas9	negative selection	2773518
44110754	44110777	17	+	27260157	MKN45	viability	AGTCCGCGGCAGGATTTCCAAGG	HDAC5	ENSG00000108840	0.297789753321785	[]	[]	5	hSpCas9	negative selection	2776441
44092435	44092458	17	+	27260157	MKN45	viability	CAGTCCCATCCTTGCGACGCAGG	HDAC5	ENSG00000108840	-1.06592331428714	[]	[]	-8	hSpCas9	negative selection	2796748
44092256	44092279	17	+	27260157	MKN45	viability	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	-3.30769018501513	[]	[]	-9	hSpCas9	negative selection	2799693
44093118	44093141	17	+	27260157	MKN45	viability	ATGGTTGAGGCCGCCTGGTGTGG	HDAC5	ENSG00000108840	-0.586092450971501	[]	[]	-6	hSpCas9	negative selection	2800041
44091769	44091792	17	+	27260157	MKN45	viability	CGTGTAGAGGCTGAACTGGTTGG	HDAC5	ENSG00000108840	-1.3733458747068	[]	[]	-8	hSpCas9	negative selection	2800043
44091349	44091372	17	-	27260157	MKN45	viability	GCGTGGCACTGGAGGGCGACGGG	HDAC5	ENSG00000108840	0.861830506535983	[]	[]	8	hSpCas9	negative selection	2800963
44110783	44110806	17	-	27260157	RKO	viability	AGCAGATGGGATGTCAGGTCGGG	HDAC5	ENSG00000108840	0.586524508943703	[]	[]	3	hSpCas9	negative selection	2804955
44110716	44110739	17	+	27260157	RKO	viability	TCAAGGCACTTACCTGTCACAGG	HDAC5	ENSG00000108840	-0.0991665870604655	[]	[]	0	hSpCas9	negative selection	2808552
44092251	44092274	17	-	27260157	RKO	viability	TGTAACAGCGCACCCGGCTCCGG	HDAC5	ENSG00000108840	-0.719549517874292	[]	[]	-7	hSpCas9	negative selection	2809288
44110788	44110811	17	-	27260157	RKO	viability	TTCTCAGCAGATGGGATGTCAGG	HDAC5	ENSG00000108840	-0.277471698068527	[]	[]	-1	hSpCas9	negative selection	2812146
44092692	44092715	17	+	27260157	RKO	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	1.14385455579363	[]	[]	9	hSpCas9	negative selection	2814977
44110728	44110751	17	-	27260157	RKO	viability	CTGCACAGCATCCCTGTGACAGG	HDAC5	ENSG00000108840	0.872291126839419	[]	[]	8	hSpCas9	negative selection	2815166
44110740	44110763	17	+	27260157	RKO	viability	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	0.271082074954945	[]	[]	1	hSpCas9	negative selection	2834572
44110771	44110794	17	-	27260157	RKO	viability	GTCAGGTCGGGAACCATCCTTGG	HDAC5	ENSG00000108840	1.2624489351533	[]	[]	9	hSpCas9	negative selection	2835386
44091464	44091487	17	+	27260157	RKO	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.408954868956775	[]	[]	-6	hSpCas9	negative selection	2838938
44093820	44093843	17	-	27260157	RKO	viability	GCCCACAGTGGAGGTGAAGCCGG	HDAC5	ENSG00000108840	0.282964068500377	[]	[]	1	hSpCas9	negative selection	2840256
44092439	44092462	17	-	27260157	RKO	viability	CCCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.42954647989526	[]	[]	-6	hSpCas9	negative selection	2849648
44110754	44110777	17	+	27260157	RKO	viability	AGTCCGCGGCAGGATTTCCAAGG	HDAC5	ENSG00000108840	0.88590268117324	[]	[]	8	hSpCas9	negative selection	2852571
44092435	44092458	17	+	27260157	RKO	viability	CAGTCCCATCCTTGCGACGCAGG	HDAC5	ENSG00000108840	-0.5866649346871879	[]	[]	-7	hSpCas9	negative selection	2872878
44092256	44092279	17	+	27260157	RKO	viability	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.286951776475589	[]	[]	1	hSpCas9	negative selection	2875823
44093118	44093141	17	+	27260157	RKO	viability	ATGGTTGAGGCCGCCTGGTGTGG	HDAC5	ENSG00000108840	0.414138579056511	[]	[]	2	hSpCas9	negative selection	2876171
44091769	44091792	17	+	27260157	RKO	viability	CGTGTAGAGGCTGAACTGGTTGG	HDAC5	ENSG00000108840	-0.527851603737372	[]	[]	-6	hSpCas9	negative selection	2876173
44091349	44091372	17	-	27260157	RKO	viability	GCGTGGCACTGGAGGGCGACGGG	HDAC5	ENSG00000108840	0.57017307109145	[]	[]	3	hSpCas9	negative selection	2877093
44110783	44110806	17	-	27260157	SF268	viability	AGCAGATGGGATGTCAGGTCGGG	HDAC5	ENSG00000108840	-0.591285799426701	[]	[]	-4	hSpCas9	negative selection	2881085
44110716	44110739	17	+	27260157	SF268	viability	TCAAGGCACTTACCTGTCACAGG	HDAC5	ENSG00000108840	0.554610175344783	[]	[]	8	hSpCas9	negative selection	2884682
44092251	44092274	17	-	27260157	SF268	viability	TGTAACAGCGCACCCGGCTCCGG	HDAC5	ENSG00000108840	-0.42041945831033	[]	[]	-3	hSpCas9	negative selection	2885418
44110788	44110811	17	-	27260157	SF268	viability	TTCTCAGCAGATGGGATGTCAGG	HDAC5	ENSG00000108840	-0.0041411369008556	[]	[]	0	hSpCas9	negative selection	2888276
44092692	44092715	17	+	27260157	SF268	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.350626409189204	[]	[]	4	hSpCas9	negative selection	2891107
44110728	44110751	17	-	27260157	SF268	viability	CTGCACAGCATCCCTGTGACAGG	HDAC5	ENSG00000108840	-0.114856133041286	[]	[]	-1	hSpCas9	negative selection	2891296
44110740	44110763	17	+	27260157	SF268	viability	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	0.574626511310167	[]	[]	8	hSpCas9	negative selection	2910702
44110771	44110794	17	-	27260157	SF268	viability	GTCAGGTCGGGAACCATCCTTGG	HDAC5	ENSG00000108840	0.743758785456247	[]	[]	8	hSpCas9	negative selection	2911516
44091464	44091487	17	+	27260157	SF268	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.18912380546146	[]	[]	-1	hSpCas9	negative selection	2915068
44093820	44093843	17	-	27260157	SF268	viability	GCCCACAGTGGAGGTGAAGCCGG	HDAC5	ENSG00000108840	0.541879382852388	[]	[]	8	hSpCas9	negative selection	2916386
44092439	44092462	17	-	27260157	SF268	viability	CCCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.473098866081288	[]	[]	-4	hSpCas9	negative selection	2925778
44110754	44110777	17	+	27260157	SF268	viability	AGTCCGCGGCAGGATTTCCAAGG	HDAC5	ENSG00000108840	0.401518125144479	[]	[]	4	hSpCas9	negative selection	2928701
44092435	44092458	17	+	27260157	SF268	viability	CAGTCCCATCCTTGCGACGCAGG	HDAC5	ENSG00000108840	-0.681651231955557	[]	[]	-5	hSpCas9	negative selection	2949008
44092256	44092279	17	+	27260157	SF268	viability	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	-0.0705538731668268	[]	[]	0	hSpCas9	negative selection	2951953
44093118	44093141	17	+	27260157	SF268	viability	ATGGTTGAGGCCGCCTGGTGTGG	HDAC5	ENSG00000108840	-0.268072411224168	[]	[]	-2	hSpCas9	negative selection	2952301
44091769	44091792	17	+	27260157	SF268	viability	CGTGTAGAGGCTGAACTGGTTGG	HDAC5	ENSG00000108840	-0.342189865307194	[]	[]	-3	hSpCas9	negative selection	2952303
44091349	44091372	17	-	27260157	SF268	viability	GCGTGGCACTGGAGGGCGACGGG	HDAC5	ENSG00000108840	0.232882214341863	[]	[]	3	hSpCas9	negative selection	2953223
44093456	44093479	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGAGATGCTGGCAGCCAAGCAG	HDAC5	ENSG00000108840	0.05869604679449834	[3,3]	[2,3]	1	hSpCas9	positive selection	2992879
44093429	44093452	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGAGATGCTGGCAGCCAAGCGG	HDAC5	ENSG00000108840	0.05869604679449834	[3,3]	[2,3]	1	hSpCas9	positive selection	2992880
44110741	44110764	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	-0.1655713148934677	[3,3]	[3,1]	-2	hSpCas9	positive selection	2992881
44093743	44093766	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCCCCCCGTAGCTCCACAGGG	HDAC5	ENSG00000108840	-0.4134192826165833	[3,3]	[1,1]	-5	hSpCas9	positive selection	2992882
44093128	44093151	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.12079689383242617	[3,3]	[2,2]	-2	hSpCas9	positive selection	2992883
44093456	44093479	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGAGATGCTGGCAGCCAAGCAG	HDAC5	ENSG00000108840	-0.09046882432543654	[3,3]	[1,2]	-1	hSpCas9	positive selection	3060737
44093429	44093452	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGAGATGCTGGCAGCCAAGCGG	HDAC5	ENSG00000108840	-0.09046882432543654	[3,3]	[1,2]	-1	hSpCas9	positive selection	3060738
44110741	44110764	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	0.3693189894900415	[3,3]	[3,2]	6	hSpCas9	positive selection	3060739
44093743	44093766	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCCCCCCGTAGCTCCACAGGG	HDAC5	ENSG00000108840	-0.5630035659506369	[3,3]	[1,0]	-7	hSpCas9	positive selection	3060740
44093128	44093151	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.11209896844117556	[3,3]	[4,1]	2	hSpCas9	positive selection	3060741
44092692	44092715		+	24336571	A375	resistance to PLX after 7 days	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.056863399773885215	[35,31]	[33,35]	2	hSpCas9	positive selection	3118627
44092692	44092715		+	24336571	A375	resistance to PLX after 14 days	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.19160313505256688	[28,30]	[15,14]	2	hSpCas9	positive selection	3176420
44092692	44092715		+	24336571	A375	viability after 7 days	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.2562679374889001	[29]	[35,31]	4	hSpCas9	negative selection	3234213
44092692	44092715		+	24336571	A375	viability after 14 days	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.09088166076699378	[29]	[28,30]	1	hSpCas9	negative selection	3292006
44092692	44092715	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.463728287567522	[209,211]	[0,0]	-3	hSpCas9	positive selection	3353122
44091465	44091488	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.2184072195205627	[177,177]	[0,0]	-1	hSpCas9	positive selection	3372313
44091464	44091487	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.20210540719146217	[175,175]	[0,0]	-1	hSpCas9	positive selection	3372314
44092784	44092807	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	-0.6851882938934047	[245,245]	[0,0]	-5	hSpCas9	positive selection	3372315
44093456	44093479	17	-	26780180	HT29	viability (Avana library 4 designs)	AGGAGATGCTGGCAGCCAAGCAG	HDAC5	ENSG00000108840	1.85325483021415	[]	[]	7	hSpCas9	negative selection	3430140
44093429	44093452	17	-	26780180	HT29	viability (Avana library 4 designs)	AGGAGATGCTGGCAGCCAAGCGG	HDAC5	ENSG00000108840	1.85325483021415	[]	[]	7	hSpCas9	negative selection	3430141
44110740	44110763	17	+	26780180	HT29	viability (Avana library 4 designs)	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	2.81841612415525	[]	[]	8	hSpCas9	negative selection	3430142
44093742	44093765	17	+	26780180	HT29	viability (Avana library 4 designs)	GAGCCCCCCGTAGCTCCACAGGG	HDAC5	ENSG00000108840	0.513571154422943	[]	[]	2	hSpCas9	negative selection	3430143
44093128	44093151	17	-	26780180	HT29	viability (Avana library 4 designs)	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.934098546217691	[]	[]	3	hSpCas9	negative selection	3430144
44093742	44093765	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCCCCCCGTAGCTCCACAGGG	HDAC5	ENSG00000108840	3.48683615085075	[]	[]	5	hSpCas9	negative selection	3515154
44093456	44093479	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAGATGCTGGCAGCCAAGCAG	HDAC5	ENSG00000108840	2.93140426459292	[]	[]	4	hSpCas9	negative selection	3515155
44093429	44093452	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAGATGCTGGCAGCCAAGCGG	HDAC5	ENSG00000108840	2.93140426459292	[]	[]	4	hSpCas9	negative selection	3515156
44110740	44110763	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	-0.145410372754894	[]	[]	0	hSpCas9	negative selection	3515157
44093128	44093151	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	2.67320807837937	[]	[]	4	hSpCas9	negative selection	3515158
44087678	44087701	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-3.78490542352576	[]	[]	-4	hSpCas9	negative selection	3515159
44088536	44088559	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGGCCACCAGCATGCGGACGG	HDAC5	ENSG00000108840	3.08855427651	[]	[]	5	hSpCas9	negative selection	3515160
44093742	44093765	17	+	26780180	A375	viability (Avana lentiGuide)	GAGCCCCCCGTAGCTCCACAGGG	HDAC5	ENSG00000108840	-4.03293238319154	[]	[]	-7	hSpCas9	negative selection	3623813
44093456	44093479	17	-	26780180	A375	viability (Avana lentiGuide)	AGGAGATGCTGGCAGCCAAGCAG	HDAC5	ENSG00000108840	2.48278940312922	[]	[]	2	hSpCas9	negative selection	3623814
44093429	44093452	17	-	26780180	A375	viability (Avana lentiGuide)	AGGAGATGCTGGCAGCCAAGCGG	HDAC5	ENSG00000108840	2.48278940312922	[]	[]	2	hSpCas9	negative selection	3623815
44110740	44110763	17	+	26780180	A375	viability (Avana lentiGuide)	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	3.4826045907715	[]	[]	3	hSpCas9	negative selection	3623816
44093128	44093151	17	-	26780180	A375	viability (Avana lentiGuide)	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-5.23742539139653	[]	[]	-8	hSpCas9	negative selection	3623817
44087678	44087701	17	-	26780180	A375	viability (Avana lentiGuide)	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	9.20937885625519	[]	[]	6	hSpCas9	negative selection	3623818
44088536	44088559	17	-	26780180	A375	viability (Avana lentiGuide)	TGTGGCCACCAGCATGCGGACGG	HDAC5	ENSG00000108840	7.60858796540886	[]	[]	6	hSpCas9	negative selection	3623819
44093742	44093765	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCCCCCCGTAGCTCCACAGGG	HDAC5	ENSG00000108840	0.2813139536568685	[4]	[5,4]	7	hSpCas9	positive selection	3732472
44093456	44093479	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAGATGCTGGCAGCCAAGCAG	HDAC5	ENSG00000108840	0.24794643686007206	[4]	[6,4]	7	hSpCas9	positive selection	3732473
44093429	44093452	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAGATGCTGGCAGCCAAGCGG	HDAC5	ENSG00000108840	0.24794643686007206	[4]	[6,4]	7	hSpCas9	positive selection	3732474
44110740	44110763	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	-0.2929010569321215	[4]	[3,2]	-4	hSpCas9	positive selection	3732475
44093128	44093151	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.06249420156551627	[4]	[4,4]	1	hSpCas9	positive selection	3732476
44087678	44087701	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	0.06645191198975256	[5]	[4,5]	1	hSpCas9	positive selection	3732477
44088536	44088559	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGGCCACCAGCATGCGGACGG	HDAC5	ENSG00000108840	0.13373287426759467	[5]	[6,5]	3	hSpCas9	positive selection	3732478
44093742	44093765	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCCCCCCGTAGCTCCACAGGG	HDAC5	ENSG00000108840	0.030445102482610516	[5]	[4,4]	0	hSpCas9	positive selection	3841079
44093456	44093479	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAGATGCTGGCAGCCAAGCAG	HDAC5	ENSG00000108840	-0.25931252418323064	[5]	[2,4]	-4	hSpCas9	positive selection	3841080
44093429	44093452	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAGATGCTGGCAGCCAAGCGG	HDAC5	ENSG00000108840	-0.25931252418323064	[5]	[2,4]	-4	hSpCas9	positive selection	3841081
44110740	44110763	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCTGTGCAGAGAAGTCCGCGG	HDAC5	ENSG00000108840	-0.23927907309512247	[5]	[4,2]	-3	hSpCas9	positive selection	3841082
44093128	44093151	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.35845261389384614	[5]	[5,6]	9	hSpCas9	positive selection	3841083
44087678	44087701	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	0.0019855847796799875	[5]	[4,4]	0	hSpCas9	positive selection	3841084
44088536	44088559	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGGCCACCAGCATGCGGACGG	HDAC5	ENSG00000108840	-0.04390420582657374	[5]	[4,5]	0	hSpCas9	positive selection	3841085
44091465	44091488	17	-	26780180	A375	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	0.925174245601218	[]	[]	4	hSpCas9	negative selection	3947152
44092692	44092715	17	+	26780180	A375	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	1.00555063507943	[]	[]	4	hSpCas9	negative selection	3947153
44092784	44092807	17	-	26780180	A375	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.680544300623903	[]	[]	2	hSpCas9	negative selection	3947154
44091464	44091487	17	+	26780180	A375	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	1.14078055286215	[]	[]	6	hSpCas9	negative selection	3947155
44091465	44091488	17	-	26780180	HT29	viability (GeCKOv2 library)	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	1.60882214747868	[]	[]	8	hSpCas9	negative selection	4055118
44092692	44092715	17	+	26780180	HT29	viability (GeCKOv2 library)	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	1.96196115014821	[]	[]	9	hSpCas9	negative selection	4055119
44092784	44092807	17	-	26780180	HT29	viability (GeCKOv2 library)	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.246633795851772	[]	[]	0	hSpCas9	negative selection	4055120
44091464	44091487	17	+	26780180	HT29	viability (GeCKOv2 library)	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	1.22998207676782	[]	[]	6	hSpCas9	negative selection	4055121
44092692	44092715	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.08713849533860846	[5]	[3,3]	2	hSpCas9	positive selection	4142064
44092692	44092715	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.4540578361608966	[5]	[0,3,2,3]	3	hSpCas9	positive selection	4206086
44092692	44092715	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.07219845182500612	[4]	[3,2]	1	hSpCas9	positive selection	4274694
44091465	44091488	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.12714160993612666	[3]	[2,1]	-3	hSpCas9	positive selection	4338955
44091464	44091487	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.033088787696617966	[2]	[1,2]	0	hSpCas9	positive selection	4338956
44092784	44092807	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.20190657686263777	[2]	[4,1]	4	hSpCas9	positive selection	4338957
44088519	44088541	17	-	27760321	OCIAML3	viability	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.34270998287353927	[715,581]	[602,688]	4	hSpCas9	negative selection	4406414
44088554	44088576	17	-	27760321	OCIAML3	viability	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.4229804003158168	[630,530]	[275,417]	-4	hSpCas9	negative selection	4406415
44088586	44088608	17	-	27760321	OCIAML3	viability	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.8512322581670381	[790,675]	[834,1287]	8	hSpCas9	negative selection	4406416
44092257	44092279	17	+	27760321	OCIAML3	viability	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.389310646070943	[555,448]	[438,606]	4	hSpCas9	negative selection	4406417
44092439	44092461	17	-	27760321	OCIAML3	viability	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.01987732537219733	[628,601]	[539,421]	0	hSpCas9	negative selection	4406418
44088519	44088541	17	-	27760321	OCIAML2	viability	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.17559478423674624	[715,581]	[459,760]	2	hSpCas9	negative selection	4489877
44088554	44088576	17	-	27760321	OCIAML2	viability	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	0.06377754610771696	[630,530]	[431,564]	0	hSpCas9	negative selection	4489878
44088586	44088608	17	-	27760321	OCIAML2	viability	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.452941154423132	[790,675]	[753,882]	6	hSpCas9	negative selection	4489879
44092257	44092279	17	+	27760321	OCIAML2	viability	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.4150196617747741	[555,448]	[428,683]	5	hSpCas9	negative selection	4489880
44092439	44092461	17	-	27760321	OCIAML2	viability	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.4026986937549868	[628,601]	[565,781]	5	hSpCas9	negative selection	4489881
44088519	44088541	17	-	27760321	MV411	viability	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	1.4492404268853591	[715,581]	[1160,1166]	9	hSpCas9	negative selection	4573340
44088554	44088576	17	-	27760321	MV411	viability	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	0.3008577037793595	[630,530]	[372,616]	2	hSpCas9	negative selection	4573341
44088586	44088608	17	-	27760321	MV411	viability	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	1.7754633527317525	[790,675]	[2218,799]	9	hSpCas9	negative selection	4573342
44092257	44092279	17	+	27760321	MV411	viability	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.84062538007932	[555,448]	[588,592]	6	hSpCas9	negative selection	4573343
44092439	44092461	17	-	27760321	MV411	viability	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.7824863335533765	[628,601]	[801,545]	6	hSpCas9	negative selection	4573344
44088519	44088541	17	-	27760321	HL60	viability	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.049459116611803355	[715,581]	[430,592]	0	hSpCas9	negative selection	4656803
44088554	44088576	17	-	27760321	HL60	viability	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.4403062077464507	[630,530]	[263,437]	-5	hSpCas9	negative selection	4656804
44088586	44088608	17	-	27760321	HL60	viability	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.5830473301938995	[790,675]	[1018,762]	7	hSpCas9	negative selection	4656805
44092257	44092279	17	+	27760321	HL60	viability	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.27303382422157174	[555,448]	[469,517]	3	hSpCas9	negative selection	4656806
44092439	44092461	17	-	27760321	HL60	viability	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.2690801522744444	[628,601]	[615,596]	3	hSpCas9	negative selection	4656807
44088519	44088541	17	-	27760321	HT1080	viability	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.5070276360668566	[581,453]	[159,128]	-2	hSpCas9	negative selection	4740266
44088554	44088576	17	-	27760321	HT1080	viability	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.5405542606659479	[530,414]	[56,208]	-2	hSpCas9	negative selection	4740267
44088586	44088608	17	-	27760321	HT1080	viability	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.7714983243880897	[675,527]	[459,353]	4	hSpCas9	negative selection	4740268
44092257	44092279	17	+	27760321	HT1080	viability	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	1.0269042202798846	[448,350]	[318,330]	5	hSpCas9	negative selection	4740269
44092439	44092461	17	-	27760321	HT1080	viability	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.1037003459374703	[601,469]	[97,308]	0	hSpCas9	negative selection	4740270
44088519	44088541	17	-	27760321	HT29	viability after 7 days	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.1728247598731908	[581,453]	[594,472,1147]	2	hSpCas9	negative selection	4823729
44088554	44088576	17	-	27760321	HT29	viability after 7 days	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.5285606467583085	[530,414]	[549,387,346]	-6	hSpCas9	negative selection	4823730
44088586	44088608	17	-	27760321	HT29	viability after 7 days	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.5552145623153295	[675,527]	[960,1436,991]	8	hSpCas9	negative selection	4823731
44092257	44092279	17	+	27760321	HT29	viability after 7 days	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.27100137291175935	[448,350]	[673,650,545]	4	hSpCas9	negative selection	4823732
44092439	44092461	17	-	27760321	HT29	viability after 7 days	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.04387788349620991	[601,469]	[670,953,388]	0	hSpCas9	negative selection	4823733
44088519	44088541	17	-	27760321	HT29	viability after 25 days	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.04036366952513004	[581,453]	[488,670,570]	0	hSpCas9	negative selection	4907192
44088554	44088576	17	-	27760321	HT29	viability after 25 days	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.4116772771634785	[530,414]	[170,512,565]	-4	hSpCas9	negative selection	4907193
44088586	44088608	17	-	27760321	HT29	viability after 25 days	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.6664099646440214	[675,527]	[1021,1126,1133]	7	hSpCas9	negative selection	4907194
44092257	44092279	17	+	27760321	HT29	viability after 25 days	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.4450273034952512	[448,350]	[594,528,757]	5	hSpCas9	negative selection	4907195
44092439	44092461	17	-	27760321	HT29	viability after 25 days	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.3533270902515116	[601,469]	[416,335,712]	-4	hSpCas9	negative selection	4907196
44088519	44088541	17	-	27760321	HT29	viability after 22 days	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.3611076027562007	[581,453]	[1098,474,723]	4	hSpCas9	negative selection	4990655
44088554	44088576	17	-	27760321	HT29	viability after 22 days	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.522864921432366	[530,414]	[126,500,521]	-5	hSpCas9	negative selection	4990656
44088586	44088608	17	-	27760321	HT29	viability after 22 days	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.5903725597789875	[675,527]	[907,1127,1111]	6	hSpCas9	negative selection	4990657
44092257	44092279	17	+	27760321	HT29	viability after 22 days	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.5723996117440387	[448,350]	[846,494,716]	6	hSpCas9	negative selection	4990658
44092439	44092461	17	-	27760321	HT29	viability after 22 days	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.33329430732850873	[601,469]	[500,506,466]	-3	hSpCas9	negative selection	4990659
44088519	44088541	17	-	27760321	HT29	viability after 19 days	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.2656192507261296	[581,453]	[819,526,796]	2	hSpCas9	negative selection	5074118
44088554	44088576	17	-	27760321	HT29	viability after 19 days	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	0.55560523433473	[530,414]	[428,569,1326]	5	hSpCas9	negative selection	5074119
44088586	44088608	17	-	27760321	HT29	viability after 19 days	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.457212460248253	[675,527]	[1124,971,763]	4	hSpCas9	negative selection	5074120
44092257	44092279	17	+	27760321	HT29	viability after 19 days	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.2073720445764589	[448,350]	[581,479,527]	2	hSpCas9	negative selection	5074121
44092439	44092461	17	-	27760321	HT29	viability after 19 days	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.29112919547435767	[601,469]	[541,560,1110]	2	hSpCas9	negative selection	5074122
44088519	44088541	17	-	27760321	HT29	viability after 16 days	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.24296946619177273	[581,453]	[755,646,661]	2	hSpCas9	negative selection	5157581
44088554	44088576	17	-	27760321	HT29	viability after 16 days	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	0.028352792244811964	[530,414]	[461,646,499]	0	hSpCas9	negative selection	5157582
44088586	44088608	17	-	27760321	HT29	viability after 16 days	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.7324740142462314	[675,527]	[1061,801,1495]	8	hSpCas9	negative selection	5157583
44092257	44092279	17	+	27760321	HT29	viability after 16 days	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.06891397613915937	[448,350]	[466,625,310]	0	hSpCas9	negative selection	5157584
44092439	44092461	17	-	27760321	HT29	viability after 16 days	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.35462082868095696	[601,469]	[600,407,411]	-4	hSpCas9	negative selection	5157585
44088519	44088541	17	-	27760321	HT29	viability after 13 days	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.24200745235986565	[581,453]	[609,911,615]	3	hSpCas9	negative selection	5241044
44088554	44088576	17	-	27760321	HT29	viability after 13 days	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.1702634278266923	[530,414]	[565,514,387]	-2	hSpCas9	negative selection	5241045
44088586	44088608	17	-	27760321	HT29	viability after 13 days	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.640677900785376	[675,527]	[1064,1308,903]	8	hSpCas9	negative selection	5241046
44092257	44092279	17	+	27760321	HT29	viability after 13 days	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.6408529301774306	[448,350]	[746,636,782]	8	hSpCas9	negative selection	5241047
44092439	44092461	17	-	27760321	HT29	viability after 13 days	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	-0.30569043645867844	[601,469]	[453,529,523]	-4	hSpCas9	negative selection	5241048
44088519	44088541	17	-	27760321	HT29	viability after 10 days	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.18454730020234578	[581,453]	[703,651,843]	2	hSpCas9	negative selection	5324507
44088554	44088576	17	-	27760321	HT29	viability after 10 days	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	-0.5696577382786241	[530,414]	[369,354,465]	-6	hSpCas9	negative selection	5324508
44088586	44088608	17	-	27760321	HT29	viability after 10 days	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.6755057352940985	[675,527]	[1228,1159,1210]	8	hSpCas9	negative selection	5324509
44092257	44092279	17	+	27760321	HT29	viability after 10 days	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.717755841351956	[448,350]	[728,898,837]	8	hSpCas9	negative selection	5324510
44092439	44092461	17	-	27760321	HT29	viability after 10 days	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.1046663468844864	[601,469]	[852,445,848]	1	hSpCas9	negative selection	5324511
44088519	44088541	17	-	27760321	MOLM13	viability	GACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.14450253091226584	[715,581]	[346,449]	1	hSpCas9	negative selection	5407970
44088554	44088576	17	-	27760321	MOLM13	viability	CTAGTGACGGGTGAACGTGTGG	HDAC5	ENSG00000108840	0.5458608337685383	[630,530]	[412,530]	4	hSpCas9	negative selection	5407971
44088586	44088608	17	-	27760321	MOLM13	viability	ACTCCGTAGTGCCACTCCACGG	HDAC5	ENSG00000108840	0.39830964047453776	[790,675]	[735,379]	2	hSpCas9	negative selection	5407972
44092257	44092279	17	+	27760321	MOLM13	viability	CCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.4866427329278713	[555,448]	[467,332]	3	hSpCas9	negative selection	5407973
44092439	44092461	17	-	27760321	MOLM13	viability	CCTCCTGCGTCGCAAGGATGGG	HDAC5	ENSG00000108840	0.06076147462335879	[628,601]	[372,353]	0	hSpCas9	negative selection	5407974
44123239	44123262	17	+	27661255	K562	viability	GGGCCCCTCCCTTACCTGTAGGG	HDAC5	ENSG00000108840	0.07450928263252976	[1462,1825]	[1583,1201]	2	dCas9-KRAB	negative selection	5484276
44123247	44123270	17	-	27661255	K562	viability	GGCGCCTTCCCTACAGGTAAGGG	HDAC5	ENSG00000108840	-0.10201794396754071	[572,458]	[431,345]	-4	dCas9-KRAB	negative selection	5484277
44092692	44092715	17	+	27260156	BXPC3	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.02054201123088406	[1019]	[957,970,1119,1320]	0	hSpCas9	negative selection	5547154
44091465	44091488	17	-	27260156	BXPC3	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.21327050744774823	[482]	[414,360,493,482]	-5	hSpCas9	negative selection	5611415
44091464	44091487	17	+	27260156	BXPC3	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.22709180617933047	[398]	[459,376,530,606]	5	hSpCas9	negative selection	5611416
44092784	44092807	17	-	27260156	BXPC3	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.24793086980038165	[413]	[544,510,408,591]	5	hSpCas9	negative selection	5611417
44092692	44092715	17	+	27260156	A673	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.12945719920743382	[1019]	[1363,1321,1399,1268]	3	hSpCas9	negative selection	5668405
44091465	44091488	17	-	27260156	A673	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.18315294791926984	[482]	[567,569,417,490]	-4	hSpCas9	negative selection	5732666
44091464	44091487	17	+	27260156	A673	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.37932610477863826	[398]	[671,547,607,673]	8	hSpCas9	negative selection	5732667
44092784	44092807	17	-	27260156	A673	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.13647572383207343	[413]	[656,479,535,524]	3	hSpCas9	negative selection	5732668
44092692	44092715	17	+	27260156	A375	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.16540039712480747	[1019]	[921,1073,1171,1075]	-2	hSpCas9	negative selection	5789656
44091465	44091488	17	-	27260156	A375	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.5574902186250537	[482]	[410,557,302,294]	-6	hSpCas9	negative selection	5853917
44091464	44091487	17	+	27260156	A375	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.20118805191696337	[398]	[494,597,378,661]	3	hSpCas9	negative selection	5853918
44092784	44092807	17	-	27260156	A375	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.6163454610678234	[413]	[858,925,621,598]	8	hSpCas9	negative selection	5853919
44092692	44092715	17	+	27260156	COLO741	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.03121263258104201	[1019]	[1578,1411,1043]	0	hSpCas9	negative selection	5910907
44091465	44091488	17	-	27260156	COLO741	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.2721080377311884	[482]	[470,522,532]	-5	hSpCas9	negative selection	5975168
44091464	44091487	17	+	27260156	COLO741	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.29610673567715784	[398]	[726,645,519]	6	hSpCas9	negative selection	5975169
44092784	44092807	17	-	27260156	COLO741	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.0932336310494482	[413]	[454,585,635]	2	hSpCas9	negative selection	5975170
44092692	44092715	17	+	27260156	CAL120	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.21084108048157413	[1019]	[1072,1645,1624]	3	hSpCas9	negative selection	6032158
44091465	44091488	17	-	27260156	CAL120	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	0.3533081751297977	[482]	[750,635,910]	5	hSpCas9	negative selection	6096419
44091464	44091487	17	+	27260156	CAL120	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.41695066926798885	[398]	[768,551,682]	6	hSpCas9	negative selection	6096420
44092784	44092807	17	-	27260156	CAL120	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.49836264154199655	[413]	[467,788,883]	7	hSpCas9	negative selection	6096421
44092692	44092715	17	+	27260156	CADOES1	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.08488290924557251	[1019]	[1112,1112,934,857]	1	hSpCas9	negative selection	6153409
44091465	44091488	17	-	27260156	CADOES1	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.17134981511849845	[482]	[440,314,372,468]	-3	hSpCas9	negative selection	6217670
44091464	44091487	17	+	27260156	CADOES1	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.16744634903171135	[398]	[360,470,298,540]	3	hSpCas9	negative selection	6217671
44092784	44092807	17	-	27260156	CADOES1	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.7100374683875792	[413]	[495,574,835,611]	9	hSpCas9	negative selection	6217672
44092692	44092715	17	+	27260156	EWS502	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.1140977918739059	[1019]	[1071,979,845,1086]	-2	hSpCas9	negative selection	6274660
44091465	44091488	17	-	27260156	EWS502	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.41431784473842603	[482]	[303,425,502,304]	-6	hSpCas9	negative selection	6338921
44091464	44091487	17	+	27260156	EWS502	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.40637852282443804	[398]	[431,511,761,551]	7	hSpCas9	negative selection	6338922
44092784	44092807	17	-	27260156	EWS502	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.2981473581081682	[413]	[275,641,581,693]	5	hSpCas9	negative selection	6338923
44092692	44092715	17	+	27260156	EW8	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.011165907354308224	[1019]	[1045,858,556,937]	0	hSpCas9	negative selection	6395911
44091465	44091488	17	-	27260156	EW8	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.3117998008141243	[482]	[391,311,303,262]	-5	hSpCas9	negative selection	6460172
44091464	44091487	17	+	27260156	EW8	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.19905607084381713	[398]	[411,370,306,408]	3	hSpCas9	negative selection	6460173
44092784	44092807	17	-	27260156	EW8	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.462406166855118	[413]	[399,575,393,482]	8	hSpCas9	negative selection	6460174
44092692	44092715	17	+	27260156	CORL105	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.185900838657184	[1019]	[1139,954,1227,908]	-3	hSpCas9	negative selection	6517162
44091465	44091488	17	-	27260156	CORL105	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.5174384004540805	[482]	[408,301,457,422]	-7	hSpCas9	negative selection	6581423
44091464	44091487	17	+	27260156	CORL105	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.22188037731890503	[398]	[567,604,620,396]	4	hSpCas9	negative selection	6581424
44092784	44092807	17	-	27260156	CORL105	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.36685021033296716	[413]	[743,494,697,580]	6	hSpCas9	negative selection	6581425
44092692	44092715	17	+	27260156	HS294T	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.07416730575417607	[1019]	[360,290,396,467]	-1	hSpCas9	negative selection	6638413
44091465	44091488	17	-	27260156	HS294T	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	0.12460101868637102	[482]	[253,155,223,170]	1	hSpCas9	negative selection	6702674
44091464	44091487	17	+	27260156	HS294T	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.22867212673887996	[398]	[131,149,156,310]	3	hSpCas9	negative selection	6702675
44092784	44092807	17	-	27260156	HS294T	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.2572509401418685	[413]	[129,284,127,230]	3	hSpCas9	negative selection	6702676
44092692	44092715	17	+	27260156	HCC44	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.13452262972948859	[1019]	[1998,1074,1215,863]	2	hSpCas9	negative selection	6759664
44091465	44091488	17	-	27260156	HCC44	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.3412960883335417	[482]	[397,234,731,432]	-5	hSpCas9	negative selection	6823925
44091464	44091487	17	+	27260156	HCC44	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.4835401101631321	[398]	[850,412,909,449]	7	hSpCas9	negative selection	6823926
44092784	44092807	17	-	27260156	HCC44	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.4922480233345314	[413]	[433,563,938,730]	7	hSpCas9	negative selection	6823927
44092692	44092715	17	+	27260156	G402	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.1460867926090912	[1019]	[1421,1461,947,743]	-2	hSpCas9	negative selection	6880915
44091465	44091488	17	-	27260156	G402	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.13283581009765594	[482]	[753,484,416,520]	-2	hSpCas9	negative selection	6945176
44091464	44091487	17	+	27260156	G402	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.132132484242523	[398]	[624,413,641,460]	1	hSpCas9	negative selection	6945177
44092784	44092807	17	-	27260156	G402	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.6172979011264027	[413]	[807,769,977,555]	7	hSpCas9	negative selection	6945178
44092692	44092715	17	+	27260156	L33	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.10597760203283046	[1019]	[1137,421,673,1148]	2	hSpCas9	negative selection	7002166
44091465	44091488	17	-	27260156	L33	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.008200754758859438	[482]	[537,204,272,446]	0	hSpCas9	negative selection	7066427
44091464	44091487	17	+	27260156	L33	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.3259752667956725	[398]	[483,216,304,501]	7	hSpCas9	negative selection	7066428
44092784	44092807	17	-	27260156	L33	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.027538770291208825	[413]	[452,160,265,417]	0	hSpCas9	negative selection	7066429
44092692	44092715	17	+	27260156	K562	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.2541077741510358	[1019]	[585,1259,1455,990]	3	hSpCas9	negative selection	7123417
44091465	44091488	17	-	27260156	K562	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	0.17095283078464896	[482]	[515,509,533,383]	2	hSpCas9	negative selection	7187678
44091464	44091487	17	+	27260156	K562	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.1773899191131886	[398]	[518,306,361,414]	2	hSpCas9	negative selection	7187679
44092784	44092807	17	-	27260156	K562	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.19757774916268886	[413]	[332,471,594,293]	2	hSpCas9	negative selection	7187680
44092692	44092715	17	+	27260156	HT29	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.06238275709392527	[1019]	[1485,1443,1304,998]	1	hSpCas9	negative selection	7244668
44091465	44091488	17	-	27260156	HT29	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.0529126657252635	[482]	[797,504,551,433]	-1	hSpCas9	negative selection	7308929
44091464	44091487	17	+	27260156	HT29	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.3327516429857856	[398]	[660,655,467,655]	6	hSpCas9	negative selection	7308930
44092784	44092807	17	-	27260156	HT29	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.4164862909328936	[413]	[746,813,620,534]	7	hSpCas9	negative selection	7308931
44092692	44092715	17	+	27260156	MHHES1	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.11169753999443466	[1019]	[1117,1478,887,842]	-2	hSpCas9	negative selection	7365919
44091465	44091488	17	-	27260156	MHHES1	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.11878307830055816	[482]	[564,733,485,288]	-2	hSpCas9	negative selection	7430180
44091464	44091487	17	+	27260156	MHHES1	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.38075885526973474	[398]	[640,551,612,535]	6	hSpCas9	negative selection	7430181
44092784	44092807	17	-	27260156	MHHES1	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.10879641628873424	[413]	[540,621,454,417]	2	hSpCas9	negative selection	7430182
44092692	44092715	17	+	27260156	MEWO	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.02000364349728323	[1019]	[974,889,964]	0	hSpCas9	negative selection	7487170
44091465	44091488	17	-	27260156	MEWO	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.24268442942692922	[482]	[481,390,291]	-5	hSpCas9	negative selection	7551431
44091464	44091487	17	+	27260156	MEWO	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.09943032870356794	[398]	[433,457,313]	2	hSpCas9	negative selection	7551432
44092784	44092807	17	-	27260156	MEWO	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	-0.2768300471644697	[413]	[470,182,334]	-6	hSpCas9	negative selection	7551433
44092692	44092715	17	+	27260156	LNCAPCLONEFGC	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.2956756576331925	[1019]	[1115,1043,1456,972]	4	hSpCas9	negative selection	7608421
44091465	44091488	17	-	27260156	LNCAPCLONEFGC	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.19199537650599655	[482]	[325,299,521,410]	-3	hSpCas9	negative selection	7672682
44091464	44091487	17	+	27260156	LNCAPCLONEFGC	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.3284492420792111	[398]	[472,350,645,379]	5	hSpCas9	negative selection	7672683
44092784	44092807	17	-	27260156	LNCAPCLONEFGC	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.5613544379526091	[413]	[528,422,759,540]	8	hSpCas9	negative selection	7672684
44092692	44092715	17	+	27260156	PANC0327	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.0820260790943872	[1019]	[767,709,1197,759]	-1	hSpCas9	negative selection	7729672
44091465	44091488	17	-	27260156	PANC0327	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	0.061681652808817766	[482]	[303,362,427,694]	0	hSpCas9	negative selection	7793933
44091464	44091487	17	+	27260156	PANC0327	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.24818102066905087	[398]	[392,284,246,277]	-4	hSpCas9	negative selection	7793934
44092784	44092807	17	-	27260156	PANC0327	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.8065814432957594	[413]	[1002,483,685,449]	9	hSpCas9	negative selection	7793935
44092692	44092715	17	+	27260156	NCIH2009	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.012283225734962766	[1019]	[1978,1298,1140]	0	hSpCas9	negative selection	7850923
44091465	44091488	17	-	27260156	NCIH2009	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.5205827417949023	[482]	[558,467,400]	-6	hSpCas9	negative selection	7915184
44091464	44091487	17	+	27260156	NCIH2009	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.06265019614307629	[398]	[678,403,684]	0	hSpCas9	negative selection	7915185
44092784	44092807	17	-	27260156	NCIH2009	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.1724775723435244	[413]	[852,446,697]	2	hSpCas9	negative selection	7915186
44092692	44092715	17	+	27260156	NCIH1373	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.4015549463762321	[1019]	[915,728,688,306]	-4	hSpCas9	negative selection	7972174
44091465	44091488	17	-	27260156	NCIH1373	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.7083514357348302	[482]	[386,216,505,58]	-6	hSpCas9	negative selection	8036435
44091464	44091487	17	+	27260156	NCIH1373	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.09187996333851303	[398]	[549,323,277,148]	-1	hSpCas9	negative selection	8036436
44092784	44092807	17	-	27260156	NCIH1373	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.5016798611953728	[413]	[593,637,479,242]	5	hSpCas9	negative selection	8036437
44092692	44092715	17	+	27260156	PATU8902	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.05798572139813052	[1019]	[1628,861,1804,1523]	0	hSpCas9	negative selection	8093425
44091465	44091488	17	-	27260156	PATU8902	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.8015481540133762	[482]	[300,323,513,366]	-6	hSpCas9	negative selection	8157686
44091464	44091487	17	+	27260156	PATU8902	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	-0.02921889398404634	[398]	[518,620,606,392]	0	hSpCas9	negative selection	8157687
44092784	44092807	17	-	27260156	PATU8902	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.8051215656089883	[413]	[872,980,1056,1111]	8	hSpCas9	negative selection	8157688
44092692	44092715	17	+	27260156	PANC1	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.06704473796543065	[1019]	[622,1244,649,890]	-1	hSpCas9	negative selection	8214676
44091465	44091488	17	-	27260156	PANC1	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.22346020253455087	[482]	[377,361,327,348]	-4	hSpCas9	negative selection	8278937
44091464	44091487	17	+	27260156	PANC1	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.12484487415738617	[398]	[297,348,459,377]	2	hSpCas9	negative selection	8278938
44092784	44092807	17	-	27260156	PANC1	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.27558773541519993	[413]	[483,708,341,262]	4	hSpCas9	negative selection	8278939
44092692	44092715	17	+	27260156	PANC0813	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.017411623174670154	[1019]	[1201,1269,1240,1138]	0	hSpCas9	negative selection	8335927
44091465	44091488	17	-	27260156	PANC0813	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.3005347376790052	[482]	[498,440,489,417]	-5	hSpCas9	negative selection	8400188
44091464	44091487	17	+	27260156	PANC0813	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.05141550898375563	[398]	[578,550,474,352]	0	hSpCas9	negative selection	8400189
44092784	44092807	17	-	27260156	PANC0813	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.05421337688502423	[413]	[651,380,554,447]	0	hSpCas9	negative selection	8400190
44092692	44092715	17	+	27260156	RDES	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.03812154005937329	[1019]	[969,996,1247,1416]	0	hSpCas9	negative selection	8457178
44091465	44091488	17	-	27260156	RDES	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.3082366849742033	[482]	[306,340,602,601]	-5	hSpCas9	negative selection	8521439
44091464	44091487	17	+	27260156	RDES	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.5379835821491907	[398]	[587,684,562,845]	8	hSpCas9	negative selection	8521440
44092784	44092807	17	-	27260156	RDES	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.5312608448735627	[413]	[516,716,740,811]	8	hSpCas9	negative selection	8521441
44092692	44092715	17	+	27260156	PC3	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.1153265413367659	[1019]	[675,878,1790,1437]	2	hSpCas9	negative selection	8578429
44091465	44091488	17	-	27260156	PC3	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	0.2076405091725873	[482]	[276,575,1242,468]	4	hSpCas9	negative selection	8642690
44091464	44091487	17	+	27260156	PC3	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.14714278003565232	[398]	[300,367,731,495]	3	hSpCas9	negative selection	8642691
44092784	44092807	17	-	27260156	PC3	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.13259557457913182	[413]	[327,361,657,555]	3	hSpCas9	negative selection	8642692
44092692	44092715	17	+	27260156	PATU8988T	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.12095010934476491	[1019]	[1290,1017,1141,808]	2	hSpCas9	negative selection	8699680
44091465	44091488	17	-	27260156	PATU8988T	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.3317370106444321	[482]	[470,306,347,349]	-5	hSpCas9	negative selection	8763941
44091464	44091487	17	+	27260156	PATU8988T	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.3099268846272887	[398]	[413,339,763,367]	5	hSpCas9	negative selection	8763942
44092784	44092807	17	-	27260156	PATU8988T	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.07258424368355308	[413]	[509,410,515,227]	1	hSpCas9	negative selection	8763943
44092692	44092715	17	+	27260156	T47D	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.08162469327580224	[1019]	[1107,1237,991,1145]	-2	hSpCas9	negative selection	8820931
44091465	44091488	17	-	27260156	T47D	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.15418757388788168	[482]	[485,388,532,627]	-3	hSpCas9	negative selection	8885192
44091464	44091487	17	+	27260156	T47D	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.26453942473058417	[398]	[666,516,543,507]	5	hSpCas9	negative selection	8885193
44092784	44092807	17	-	27260156	T47D	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.2394533547521842	[413]	[514,566,511,687]	5	hSpCas9	negative selection	8885194
44092692	44092715	17	+	27260156	SU8686	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.17659700716820792	[1019]	[816,645,1284,872]	-3	hSpCas9	negative selection	8942182
44091465	44091488	17	-	27260156	SU8686	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.26226400055988464	[482]	[419,391,424,347]	-4	hSpCas9	negative selection	9006443
44091464	44091487	17	+	27260156	SU8686	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.048613084480789215	[398]	[312,346,529,476]	0	hSpCas9	negative selection	9006444
44092784	44092807	17	-	27260156	SU8686	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.1987924135804244	[413]	[389,396,513,624]	3	hSpCas9	negative selection	9006445
44092692	44092715	17	+	27260156	SKES1	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.1450458654907667	[1019]	[1211,1185,1031,1083]	3	hSpCas9	negative selection	9063433
44091465	44091488	17	-	27260156	SKES1	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.3558687675321855	[482]	[453,384,301,373]	-7	hSpCas9	negative selection	9127694
44091464	44091487	17	+	27260156	SKES1	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.3533622980997738	[398]	[561,596,564,341]	7	hSpCas9	negative selection	9127695
44092784	44092807	17	-	27260156	SKES1	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.333701558780549	[413]	[499,516,630,433]	7	hSpCas9	negative selection	9127696
44092692	44092715	17	+	27260156	TOV112D	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	-0.0406646436684901	[1019]	[1287,1297,674,814]	-1	hSpCas9	negative selection	9184684
44091465	44091488	17	-	27260156	TOV112D	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.6097279883567059	[482]	[411,400,231,252]	-8	hSpCas9	negative selection	9248945
44091464	44091487	17	+	27260156	TOV112D	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.2188746148009665	[398]	[426,657,431,388]	4	hSpCas9	negative selection	9248946
44092784	44092807	17	-	27260156	TOV112D	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.12900910967917778	[413]	[423,605,435,383]	2	hSpCas9	negative selection	9248947
44092692	44092715	17	+	27260156	TC71	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.08211432785704997	[1019]	[1003,1178,1155,1302]	2	hSpCas9	negative selection	9305935
44091465	44091488	17	-	27260156	TC71	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.18694323017246678	[482]	[483,511,403,417]	-5	hSpCas9	negative selection	9370196
44091464	44091487	17	+	27260156	TC71	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.31745100262152914	[398]	[659,511,461,494]	7	hSpCas9	negative selection	9370197
44092784	44092807	17	-	27260156	TC71	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.29899405214990205	[413]	[595,483,480,628]	7	hSpCas9	negative selection	9370198
44092692	44092715	17	+	27260156	TC32	viability	GAAGTCGTCTCGACTGTCGTAGG	HDAC5	ENSG00000108840	0.0658647447500551	[1019]	[930,804,1221,1122]	1	hSpCas9	negative selection	9427186
44091465	44091488	17	-	27260156	TC32	viability	CCCGAAGCTGTCGACACAGCAGG	HDAC5	ENSG00000108840	-0.3340193133262434	[482]	[390,255,359,451]	-6	hSpCas9	negative selection	9491447
44091464	44091487	17	+	27260156	TC32	viability	TCCTGCTGTGTCGACAGCTTCGG	HDAC5	ENSG00000108840	0.1419573498735321	[398]	[366,310,562,462]	2	hSpCas9	negative selection	9491448
44092784	44092807	17	-	27260156	TC32	viability	GGGAGCCCACCATGCTTCTTTGG	HDAC5	ENSG00000108840	0.3160176038178919	[413]	[430,320,638,621]	5	hSpCas9	negative selection	9491449
44092256	44092279	17	+	27869803	HPAFII	viability after 27 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	1.1794768700222347	[395]	[560,396,NaN]	8	hSpCas9	negative selection	9561109
44092440	44092463	17	+	27869803	HPAFII	viability after 27 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.05331072267659187	[524]	[259,270,NaN]	0	hSpCas9	negative selection	9561110
44092699	44092722	17	+	27869803	HPAFII	viability after 27 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	-0.08746158050648245	[148]	[82,65,NaN]	0	hSpCas9	negative selection	9561111
44093128	44093151	17	-	27869803	HPAFII	viability after 27 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-1.069441845824401	[351]	[115,64,NaN]	-6	hSpCas9	negative selection	9561112
44093745	44093768	17	-	27869803	HPAFII	viability after 27 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.475183935214448	[178]	[138,123,NaN]	4	hSpCas9	negative selection	9561113
44110758	44110781	17	+	27869803	HPAFII	viability after 27 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.6607600662717217	[665]	[486,608,NaN]	5	hSpCas9	negative selection	9561114
44092256	44092279	17	+	27869803	HPAFII	viability after 15 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.9827795896308582	[395]	[1223,602,NaN]	9	hSpCas9	negative selection	9643558
44092440	44092463	17	+	27869803	HPAFII	viability after 15 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.40024208131370864	[524]	[466,402,NaN]	-4	hSpCas9	negative selection	9643559
44092699	44092722	17	+	27869803	HPAFII	viability after 15 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	0.6292949056142432	[148]	[399,152,NaN]	7	hSpCas9	negative selection	9643560
44093128	44093151	17	-	27869803	HPAFII	viability after 15 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.8495488455781195	[351]	[315,143,NaN]	-7	hSpCas9	negative selection	9643561
44093745	44093768	17	-	27869803	HPAFII	viability after 15 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.35170609001167985	[178]	[271,228,NaN]	4	hSpCas9	negative selection	9643562
44110758	44110781	17	+	27869803	HPAFII	viability after 15 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.5186870429137878	[665]	[1186,924,NaN]	6	hSpCas9	negative selection	9643563
44092256	44092279	17	+	27869803	ASPC1	viability after 36 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	-0.13827085900767733	[1397]	[687,333,353]	-1	hSpCas9	negative selection	9726007
44092440	44092463	17	+	27869803	ASPC1	viability after 36 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.3451503893726915	[998]	[516,249,120]	-4	hSpCas9	negative selection	9726008
44092699	44092722	17	+	27869803	ASPC1	viability after 36 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	1.1060750388382095	[335]	[208,170,344]	9	hSpCas9	negative selection	9726009
44093128	44093151	17	-	27869803	ASPC1	viability after 36 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.997317822995322	[934]	[117,50,282]	-7	hSpCas9	negative selection	9726010
44093745	44093768	17	-	27869803	ASPC1	viability after 36 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-1.3201233182714462	[537]	[34,138,51]	-8	hSpCas9	negative selection	9726011
44110758	44110781	17	+	27869803	ASPC1	viability after 36 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.9895083781534315	[1643]	[947,1055,1327]	8	hSpCas9	negative selection	9726012
44092256	44092279	17	+	27869803	PATU8988S	viability after 35 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.3149530676759764	[1056]	[558,499,NaN]	3	hSpCas9	negative selection	9808456
44092440	44092463	17	+	27869803	PATU8988S	viability after 35 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.18658371867277668	[860]	[457,330,NaN]	2	hSpCas9	negative selection	9808457
44092699	44092722	17	+	27869803	PATU8988S	viability after 35 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	-0.9125487608544115	[333]	[54,87,NaN]	-7	hSpCas9	negative selection	9808458
44093128	44093151	17	-	27869803	PATU8988S	viability after 35 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	0.06921142874705816	[656]	[325,228,NaN]	0	hSpCas9	negative selection	9808459
44093745	44093768	17	-	27869803	PATU8988S	viability after 35 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.41499047838107805	[345]	[111,96,NaN]	-4	hSpCas9	negative selection	9808460
44110758	44110781	17	+	27869803	PATU8988S	viability after 35 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.717243849676976	[1701]	[1107,1145,NaN]	7	hSpCas9	negative selection	9808461
44092256	44092279	17	+	27869803	PATU8988S	viability after 31 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.41609400021507126	[1056]	[436,721,NaN]	5	hSpCas9	negative selection	9890905
44092440	44092463	17	+	27869803	PATU8988S	viability after 31 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.01221842141938867	[860]	[336,357,NaN]	0	hSpCas9	negative selection	9890906
44092699	44092722	17	+	27869803	PATU8988S	viability after 31 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	-0.47166133991495907	[333]	[99,90,NaN]	-5	hSpCas9	negative selection	9890907
44093128	44093151	17	-	27869803	PATU8988S	viability after 31 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.2061719413627271	[656]	[267,174,NaN]	-2	hSpCas9	negative selection	9890908
44093745	44093768	17	-	27869803	PATU8988S	viability after 31 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	-0.94383555866472	[345]	[76,64,NaN]	-7	hSpCas9	negative selection	9890909
44110758	44110781	17	+	27869803	PATU8988S	viability after 31 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.6384251863269614	[1701]	[978,1154,NaN]	7	hSpCas9	negative selection	9890910
44092256	44092279	17	+	27869803	HPAFII	viability after 35 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.8957178890228554	[395]	[467,265,NaN]	6	hSpCas9	negative selection	9973354
44092440	44092463	17	+	27869803	HPAFII	viability after 35 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	0.20099017359842342	[524]	[265,349,NaN]	1	hSpCas9	negative selection	9973355
44092699	44092722	17	+	27869803	HPAFII	viability after 35 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	-0.07469859049149241	[148]	[25,122,NaN]	0	hSpCas9	negative selection	9973356
44093128	44093151	17	-	27869803	HPAFII	viability after 35 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.07531686651248243	[351]	[202,130,NaN]	0	hSpCas9	negative selection	9973357
44093745	44093768	17	-	27869803	HPAFII	viability after 35 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.2751673842599436	[178]	[135,79,NaN]	1	hSpCas9	negative selection	9973358
44110758	44110781	17	+	27869803	HPAFII	viability after 35 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	1.131538742431713	[665]	[590,904,NaN]	7	hSpCas9	negative selection	9973359
44092256	44092279	17	+	27869803	HPAFII	viability after 31 days	GCCGGGTGCGCTGTTACACACGG	HDAC5	ENSG00000108840	0.9537643160278997	[395]	[518,333,NaN]	7	hSpCas9	negative selection	10055803
44092440	44092463	17	+	27869803	HPAFII	viability after 31 days	CCATCCTTGCGACGCAGGAGGGG	HDAC5	ENSG00000108840	-0.006147598959694411	[524]	[234,356,NaN]	0	hSpCas9	negative selection	10055804
44092699	44092722	17	+	27869803	HPAFII	viability after 31 days	TCTCGACTGTCGTAGGGCCCAGG	HDAC5	ENSG00000108840	-0.2332951669481328	[148]	[62,79,NaN]	-1	hSpCas9	negative selection	10055805
44093128	44093151	17	-	27869803	HPAFII	viability after 31 days	TCAAAGGAGCCCACACCAGGCGG	HDAC5	ENSG00000108840	-0.7538472749862664	[351]	[153,76,NaN]	-5	hSpCas9	negative selection	10055806
44093745	44093768	17	-	27869803	HPAFII	viability after 31 days	CAGCCCTGTGGAGCTACGGGGGG	HDAC5	ENSG00000108840	0.1899287323212236	[178]	[138,87,NaN]	1	hSpCas9	negative selection	10055807
44110758	44110781	17	+	27869803	HPAFII	viability after 31 days	CGCGGCAGGATTTCCAAGGATGG	HDAC5	ENSG00000108840	0.9731937964866622	[665]	[739,726,NaN]	7	hSpCas9	negative selection	10055808
44091462	44091485	17	-	28162770	P31FUJ	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	0.4393122454018594	[90]	[144]	5	hSpCas9	negative selection	10167918
44087645	44087668	17	-	28162770	P31FUJ	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-1.870437388605586	[780]	[250]	-8	hSpCas9	negative selection	10167919
44091321	44091344	17	+	28162770	P31FUJ	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	0.7671977955856217	[20]	[41]	8	hSpCas9	negative selection	10167920
44093175	44093198	17	-	28162770	P31FUJ	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	-0.01743704997189921	[440]	[511]	0	hSpCas9	negative selection	10167921
44092199	44092222	17	+	28162770	P31FUJ	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.3235911441100067	[135]	[199]	3	hSpCas9	negative selection	10167922
44091709	44091732	17	+	28162770	P31FUJ	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.12503088631535775	[360]	[388]	-1	hSpCas9	negative selection	10167923
44091350	44091373	17	-	28162770	P31FUJ	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-0.43443606558402914	[22]	[19]	-4	hSpCas9	negative selection	10167924
44088519	44088542	17	-	28162770	P31FUJ	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.3738145139414524	[493]	[447]	-3	hSpCas9	negative selection	10167925
44088386	44088409	17	-	28162770	P31FUJ	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	-0.011587974275211688	[174]	[203]	0	hSpCas9	negative selection	10167926
44087678	44087701	17	-	28162770	P31FUJ	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.21678480707701042	[626]	[633]	-2	hSpCas9	negative selection	10167927
44091462	44091485	17	-	28162770	TF1	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10337284
44087645	44087668	17	-	28162770	TF1	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10337285
44091321	44091344	17	+	28162770	TF1	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10337286
44093175	44093198	17	-	28162770	TF1	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	NaN	[NaN]	[423]	1	hSpCas9	negative selection	10337287
44092199	44092222	17	+	28162770	TF1	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	NaN	[NaN]	[227]	1	hSpCas9	negative selection	10337288
44091709	44091732	17	+	28162770	TF1	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	NaN	[NaN]	[286]	1	hSpCas9	negative selection	10337289
44091350	44091373	17	-	28162770	TF1	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10337290
44088519	44088542	17	-	28162770	TF1	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10337291
44088386	44088409	17	-	28162770	TF1	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10337292
44087678	44087701	17	-	28162770	TF1	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	NaN	[NaN]	[562]	1	hSpCas9	negative selection	10337293
44091462	44091485	17	-	28162770	SKM1	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	0.13069258719963772	[30]	[59]	1	hSpCas9	negative selection	10506650
44087645	44087668	17	-	28162770	SKM1	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-0.9555848524005974	[146]	[133]	-6	hSpCas9	negative selection	10506651
44091321	44091344	17	+	28162770	SKM1	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-0.8220016980220057	[2]	[2]	-6	hSpCas9	negative selection	10506652
44093175	44093198	17	-	28162770	SKM1	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.6768041589494362	[91]	[259]	6	hSpCas9	negative selection	10506653
44092199	44092222	17	+	28162770	SKM1	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.06078855760912203	[58]	[99]	0	hSpCas9	negative selection	10506654
44091709	44091732	17	+	28162770	SKM1	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.10030286050910975	[113]	[187]	-1	hSpCas9	negative selection	10506655
44091350	44091373	17	-	28162770	SKM1	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-2.6293566200796095	[6]	[1]	-9	hSpCas9	negative selection	10506656
44088519	44088542	17	-	28162770	SKM1	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.6205165376789453	[77]	[211]	6	hSpCas9	negative selection	10506657
44088386	44088409	17	-	28162770	SKM1	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.15888947903028977	[37]	[74]	1	hSpCas9	negative selection	10506658
44087678	44087701	17	-	28162770	SKM1	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.2038723333656498	[128]	[197]	-2	hSpCas9	negative selection	10506659
44091462	44091485	17	-	28162770	SKM1	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	0.13069258719963772	[30]	[59]	1	hSpCas9	negative selection	10676016
44087645	44087668	17	-	28162770	SKM1	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-0.9555848524005974	[146]	[133]	-6	hSpCas9	negative selection	10676017
44091321	44091344	17	+	28162770	SKM1	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-0.8220016980220057	[2]	[2]	-6	hSpCas9	negative selection	10676018
44093175	44093198	17	-	28162770	SKM1	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.6768041589494362	[91]	[259]	6	hSpCas9	negative selection	10676019
44092199	44092222	17	+	28162770	SKM1	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.06078855760912203	[58]	[99]	0	hSpCas9	negative selection	10676020
44091709	44091732	17	+	28162770	SKM1	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.10030286050910975	[113]	[187]	-1	hSpCas9	negative selection	10676021
44091350	44091373	17	-	28162770	SKM1	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-2.6293566200796095	[6]	[1]	-9	hSpCas9	negative selection	10676022
44088519	44088542	17	-	28162770	SKM1	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.6205165376789453	[77]	[211]	6	hSpCas9	negative selection	10676023
44088386	44088409	17	-	28162770	SKM1	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.15888947903028977	[37]	[74]	1	hSpCas9	negative selection	10676024
44087678	44087701	17	-	28162770	SKM1	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.2038723333656498	[128]	[197]	-2	hSpCas9	negative selection	10676025
44091462	44091485	17	-	28162770	PL21	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	-0.7067509811191985	[74]	[19]	-5	hSpCas9	negative selection	10845382
44087645	44087668	17	-	28162770	PL21	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	0.09280557037799819	[529]	[245]	0	hSpCas9	negative selection	10845383
44091321	44091344	17	+	28162770	PL21	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	1.04813652104427	[9]	[8]	8	hSpCas9	negative selection	10845384
44093175	44093198	17	-	28162770	PL21	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.541498239325584	[471]	[298]	5	hSpCas9	negative selection	10845385
44092199	44092222	17	+	28162770	PL21	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.333292585591754	[219]	[75]	-2	hSpCas9	negative selection	10845386
44091709	44091732	17	+	28162770	PL21	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.08099659771978429	[400]	[164]	0	hSpCas9	negative selection	10845387
44091350	44091373	17	-	28162770	PL21	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	0.2432083363812061	[32]	[16]	2	hSpCas9	negative selection	10845388
44088519	44088542	17	-	28162770	PL21	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.23778177546286233	[232]	[85]	-2	hSpCas9	negative selection	10845389
44088386	44088409	17	-	28162770	PL21	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	-0.21489788478952354	[159]	[59]	-1	hSpCas9	negative selection	10845390
44087678	44087701	17	-	28162770	PL21	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	0.35144893776428554	[415]	[230]	3	hSpCas9	negative selection	10845391
44091462	44091485	17	-	28162770	P31FUJ	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	0.4393122454018594	[90]	[144]	5	hSpCas9	negative selection	11014748
44087645	44087668	17	-	28162770	P31FUJ	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-1.870437388605586	[780]	[250]	-8	hSpCas9	negative selection	11014749
44091321	44091344	17	+	28162770	P31FUJ	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	0.7671977955856217	[20]	[41]	8	hSpCas9	negative selection	11014750
44093175	44093198	17	-	28162770	P31FUJ	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	-0.01743704997189921	[440]	[511]	0	hSpCas9	negative selection	11014751
44092199	44092222	17	+	28162770	P31FUJ	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.3235911441100067	[135]	[199]	3	hSpCas9	negative selection	11014752
44091709	44091732	17	+	28162770	P31FUJ	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.12503088631535775	[360]	[388]	-1	hSpCas9	negative selection	11014753
44091350	44091373	17	-	28162770	P31FUJ	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-0.43443606558402914	[22]	[19]	-4	hSpCas9	negative selection	11014754
44088519	44088542	17	-	28162770	P31FUJ	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.3738145139414524	[493]	[447]	-3	hSpCas9	negative selection	11014755
44088386	44088409	17	-	28162770	P31FUJ	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	-0.011587974275211688	[174]	[203]	0	hSpCas9	negative selection	11014756
44087678	44087701	17	-	28162770	P31FUJ	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.21678480707701042	[626]	[633]	-2	hSpCas9	negative selection	11014757
44091462	44091485	17	-	28162770	OCIAML5	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	-1.1739946657513594	[29]	[23]	-6	hSpCas9	negative selection	11184114
44087645	44087668	17	-	28162770	OCIAML5	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-1.9604427319087887	[303]	[140]	-8	hSpCas9	negative selection	11184115
44091321	44091344	17	+	28162770	OCIAML5	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-5.021991572306309	[17]	[0]	-9	hSpCas9	negative selection	11184116
44093175	44093198	17	-	28162770	OCIAML5	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	-0.11866759171798291	[242]	[403]	-1	hSpCas9	negative selection	11184117
44092199	44092222	17	+	28162770	OCIAML5	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.15014792379699138	[149]	[243]	-1	hSpCas9	negative selection	11184118
44091709	44091732	17	+	28162770	OCIAML5	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.5975891252844228	[174]	[477]	5	hSpCas9	negative selection	11184119
44091350	44091373	17	-	28162770	OCIAML5	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	1.3907899530321666	[14]	[70]	9	hSpCas9	negative selection	11184120
44088519	44088542	17	-	28162770	OCIAML5	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.07131214753309045	[144]	[274]	0	hSpCas9	negative selection	11184121
44088386	44088409	17	-	28162770	OCIAML5	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	-0.48949649147928853	[104]	[134]	-3	hSpCas9	negative selection	11184122
44087678	44087701	17	-	28162770	OCIAML5	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.005062572153393008	[322]	[580]	0	hSpCas9	negative selection	11184123
44091462	44091485	17	-	28162770	EOL1	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	-1.1936336547777795	[177]	[40]	-7	hSpCas9	negative selection	11353480
44087645	44087668	17	-	28162770	EOL1	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-0.3930348530408635	[662]	[265]	-3	hSpCas9	negative selection	11353481
44091321	44091344	17	+	28162770	EOL1	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-1.9823428240379841	[29]	[3]	-8	hSpCas9	negative selection	11353482
44093175	44093198	17	-	28162770	EOL1	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.95319797632728	[697]	[711]	7	hSpCas9	negative selection	11353483
44092199	44092222	17	+	28162770	EOL1	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.08862369731615938	[356]	[199]	0	hSpCas9	negative selection	11353484
44091709	44091732	17	+	28162770	EOL1	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.16810151639513982	[626]	[293]	-1	hSpCas9	negative selection	11353485
44091350	44091373	17	-	28162770	EOL1	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	0.11719284951293041	[20]	[11]	1	hSpCas9	negative selection	11353486
44088519	44088542	17	-	28162770	EOL1	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.5888614681255875	[353]	[123]	-4	hSpCas9	negative selection	11353487
44088386	44088409	17	-	28162770	EOL1	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.28231046549762917	[166]	[106]	2	hSpCas9	negative selection	11353488
44087678	44087701	17	-	28162770	EOL1	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	0.2888655132415101	[549]	[353]	2	hSpCas9	negative selection	11353489
44091462	44091485	17	-	28162770	MOLM13	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	-0.3842651504840273	[138]	[76]	-2	hSpCas9	negative selection	11522846
44087645	44087668	17	-	28162770	MOLM13	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-1.4659295414709435	[702]	[183]	-6	hSpCas9	negative selection	11522847
44091321	44091344	17	+	28162770	MOLM13	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	2.7898174764319412	[19]	[99]	9	hSpCas9	negative selection	11522848
44093175	44093198	17	-	28162770	MOLM13	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	1.1870372296601324	[553]	[911]	8	hSpCas9	negative selection	11522849
44092199	44092222	17	+	28162770	MOLM13	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.8562095424476432	[326]	[427]	6	hSpCas9	negative selection	11522850
44091709	44091732	17	+	28162770	MOLM13	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.4086327959878042	[496]	[476]	3	hSpCas9	negative selection	11522851
44091350	44091373	17	-	28162770	MOLM13	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	1.7379785449123228	[16]	[40]	9	hSpCas9	negative selection	11522852
44088519	44088542	17	-	28162770	MOLM13	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.12620413092870597	[316]	[209]	-1	hSpCas9	negative selection	11522853
44088386	44088409	17	-	28162770	MOLM13	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.11830494375435106	[236]	[185]	0	hSpCas9	negative selection	11522854
44087678	44087701	17	-	28162770	MOLM13	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	0.5855844242143333	[599]	[650]	4	hSpCas9	negative selection	11522855
44091462	44091485	17	-	28162770	HEL	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	0.4183072653903105	[117]	[100]	3	hSpCas9	negative selection	11692212
44087645	44087668	17	-	28162770	HEL	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-1.2549332335787828	[584]	[156]	-6	hSpCas9	negative selection	11692213
44091321	44091344	17	+	28162770	HEL	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-4.311457478386519	[30]	[0]	-9	hSpCas9	negative selection	11692214
44093175	44093198	17	-	28162770	HEL	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.5215371205795225	[483]	[444]	4	hSpCas9	negative selection	11692215
44092199	44092222	17	+	28162770	HEL	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.31651059967936906	[251]	[200]	2	hSpCas9	negative selection	11692216
44091709	44091732	17	+	28162770	HEL	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.9169137954393514	[386]	[467]	7	hSpCas9	negative selection	11692217
44091350	44091373	17	-	28162770	HEL	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-3.0577008861407355	[12]	[0]	-8	hSpCas9	negative selection	11692218
44088519	44088542	17	-	28162770	HEL	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.23488716910296673	[304]	[165]	-2	hSpCas9	negative selection	11692219
44088386	44088409	17	-	28162770	HEL	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	-0.6467677851946281	[153]	[62]	-4	hSpCas9	negative selection	11692220
44087678	44087701	17	-	28162770	HEL	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.08717200463189867	[543]	[327]	0	hSpCas9	negative selection	11692221
44091462	44091485	17	-	28162770	MV411	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	1.4498269474715992	[82]	[190]	9	hSpCas9	negative selection	11861578
44087645	44087668	17	-	28162770	MV411	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	0.28052833725119775	[430]	[440]	2	hSpCas9	negative selection	11861579
44091321	44091344	17	+	28162770	MV411	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	0.7880059321454782	[10]	[15]	7	hSpCas9	negative selection	11861580
44093175	44093198	17	-	28162770	MV411	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.9590620156064396	[424]	[695]	8	hSpCas9	negative selection	11861581
44092199	44092222	17	+	28162770	MV411	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.3959973526578449	[213]	[136]	-3	hSpCas9	negative selection	11861582
44091709	44091732	17	+	28162770	MV411	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.3765468387675649	[355]	[230]	-3	hSpCas9	negative selection	11861583
44091350	44091373	17	-	28162770	MV411	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	1.9974592977744279	[10]	[36]	9	hSpCas9	negative selection	11861584
44088519	44088542	17	-	28162770	MV411	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.7206896640069147	[254]	[353]	6	hSpCas9	negative selection	11861585
44088386	44088409	17	-	28162770	MV411	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	1.7771705307835393	[70]	[204]	9	hSpCas9	negative selection	11861586
44087678	44087701	17	-	28162770	MV411	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	0.7570667262786428	[379]	[540]	6	hSpCas9	negative selection	11861587
44091462	44091485	17	-	28162770	MONOMAC1	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	-0.3614236649604362	[64]	[57]	-3	hSpCas9	negative selection	12030944
44087645	44087668	17	-	28162770	MONOMAC1	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-0.610287726864383	[268]	[201]	-5	hSpCas9	negative selection	12030945
44091321	44091344	17	+	28162770	MONOMAC1	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-1.1970368470595534	[13]	[6]	-7	hSpCas9	negative selection	12030946
44093175	44093198	17	-	28162770	MONOMAC1	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.17860183457257617	[231]	[300]	1	hSpCas9	negative selection	12030947
44092199	44092222	17	+	28162770	MONOMAC1	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-1.0250841642702588	[157]	[88]	-7	hSpCas9	negative selection	12030948
44091709	44091732	17	+	28162770	MONOMAC1	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.9713240674314944	[247]	[144]	-6	hSpCas9	negative selection	12030949
44091350	44091373	17	-	28162770	MONOMAC1	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	0.6103180749980504	[7]	[13]	6	hSpCas9	negative selection	12030950
44088519	44088542	17	-	28162770	MONOMAC1	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.24434256183791037	[185]	[179]	-2	hSpCas9	negative selection	12030951
44088386	44088409	17	-	28162770	MONOMAC1	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	1.925944652772483	[58]	[256]	9	hSpCas9	negative selection	12030952
44087678	44087701	17	-	28162770	MONOMAC1	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.10612835086134331	[245]	[261]	-1	hSpCas9	negative selection	12030953
44091462	44091485	17	-	28162770	OCIAML2	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	1.0439433475875968	[13]	[159]	8	hSpCas9	negative selection	12200310
44087645	44087668	17	-	28162770	OCIAML2	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-0.9477282926532566	[94]	[272]	-6	hSpCas9	negative selection	12200311
44091321	44091344	17	+	28162770	OCIAML2	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	2.0529321308148516	[0]	[22]	9	hSpCas9	negative selection	12200312
44093175	44093198	17	-	28162770	OCIAML2	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	0.8302366541173715	[68]	[679]	7	hSpCas9	negative selection	12200313
44092199	44092222	17	+	28162770	OCIAML2	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	0.804164294054106	[27]	[270]	7	hSpCas9	negative selection	12200314
44091709	44091732	17	+	28162770	OCIAML2	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	0.5180548615300046	[63]	[507]	5	hSpCas9	negative selection	12200315
44091350	44091373	17	-	28162770	OCIAML2	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	2.8147723936200872	[1]	[77]	9	hSpCas9	negative selection	12200316
44088519	44088542	17	-	28162770	OCIAML2	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	0.8200473356607615	[41]	[410]	7	hSpCas9	negative selection	12200317
44088386	44088409	17	-	28162770	OCIAML2	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	0.9593580155026542	[17]	[193]	8	hSpCas9	negative selection	12200318
44087678	44087701	17	-	28162770	OCIAML2	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	0.685021045218033	[78]	[703]	6	hSpCas9	negative selection	12200319
44091462	44091485	17	-	28162770	OCIAML3	viability	GAAGCTGTCGACACAGCAGGAGG	HDAC5	ENSG00000108840	0.2935176304174243	[19]	[73]	2	hSpCas9	negative selection	12369676
44087645	44087668	17	-	28162770	OCIAML3	viability	GCAGCCCACCACCCACCCTGAGG	HDAC5	ENSG00000108840	-0.913380030307769	[140]	[225]	-6	hSpCas9	negative selection	12369677
44091321	44091344	17	+	28162770	OCIAML3	viability	GCAGCAGGGAGGCATGCCCGTGG	HDAC5	ENSG00000108840	-2.33097323449037	[9]	[5]	-9	hSpCas9	negative selection	12369678
44093175	44093198	17	-	28162770	OCIAML3	viability	CCAGCACTGAGGTAAAGCTGAGG	HDAC5	ENSG00000108840	-0.5065447990738237	[103]	[220]	-4	hSpCas9	negative selection	12369679
44092199	44092222	17	+	28162770	OCIAML3	viability	AGTAAAGCCATTCTCAGCGATGG	HDAC5	ENSG00000108840	-0.05211386149489283	[67]	[197]	0	hSpCas9	negative selection	12369680
44091709	44091732	17	+	28162770	OCIAML3	viability	TGAGTTGGTGACAGTGACCGTGG	HDAC5	ENSG00000108840	-0.60649858450736	[115]	[229]	-4	hSpCas9	negative selection	12369681
44091350	44091373	17	-	28162770	OCIAML3	viability	GGCGTGGCACTGGAGGGCGACGG	HDAC5	ENSG00000108840	-2.33097323449037	[4]	[2]	-9	hSpCas9	negative selection	12369682
44088519	44088542	17	-	28162770	OCIAML3	viability	GGACGGTAGGCAAGCTCCCGCGG	HDAC5	ENSG00000108840	-0.4095830691867356	[76]	[174]	-3	hSpCas9	negative selection	12369683
44088386	44088409	17	-	28162770	OCIAML3	viability	GCAGCAGCTACAGCTGGGCAAGG	HDAC5	ENSG00000108840	-0.45104968648212024	[47]	[105]	-3	hSpCas9	negative selection	12369684
44087678	44087701	17	-	28162770	OCIAML3	viability	TCAGATCCTCACCAAGACAGGGG	HDAC5	ENSG00000108840	-0.33097323449036953	[124]	[299]	-3	hSpCas9	negative selection	12369685