Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:55869
• Symbol:HDAC8
• Description:histone deacetylase 8

DataSource: http://genomecrispr.dkfz.de/#!/results/HDAC8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
72572746	72572769	X	-	26472758	Jiyoye	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-0.5403571985999909	[53]	[27]	-4	hSpCas9	negative selection	69794
72495205	72495228	X	-	26472758	Jiyoye	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	1.2216197283497972	[28]	[50]	7	hSpCas9	negative selection	69795
72572730	72572753	X	-	26472758	Jiyoye	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	1.9921378822270288	[0]	[2]	8	hSpCas9	negative selection	69796
72572651	72572674	X	+	26472758	Jiyoye	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	5.451569500864326	[0]	[32]	9	hSpCas9	negative selection	69797
72572721	72572744	X	+	26472758	Jiyoye	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.5257104226355895	[461]	[241]	-4	hSpCas9	negative selection	69798
72572695	72572718	X	+	26472758	Jiyoye	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-0.6177709756243572	[174]	[85]	-4	hSpCas9	negative selection	69799
72572056	72572079	X	-	26472758	Jiyoye	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.3215996497997994	[190]	[179]	2	hSpCas9	negative selection	69800
72572676	72572699	X	+	26472758	Jiyoye	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.9480898972556013	[196]	[76]	-6	hSpCas9	negative selection	69801
72568817	72568840	X	+	26472758	Jiyoye	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.07460004241900287	[67]	[53]	0	hSpCas9	negative selection	69802
72567907	72567930	X	-	26472758	Jiyoye	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.1629138427337526	[192]	[64]	-7	hSpCas9	negative selection	69803
72572746	72572769	X	-	26472758	KBM7	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.05181524996688047	[197,89]	[70,64]	0	hSpCas9	negative selection	260912
72495205	72495228	X	-	26472758	KBM7	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	1.0004449694048887	[122,266]	[195,186]	9	hSpCas9	negative selection	260913
72572730	72572753	X	-	26472758	KBM7	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-0.21754999755389992	[8,13]	[8,0]	-2	hSpCas9	negative selection	260914
72572651	72572674	X	+	26472758	KBM7	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	0.30453936174275054	[73,65]	[47,33]	3	hSpCas9	negative selection	260915
72572721	72572744	X	+	26472758	KBM7	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.2090820100015479	[1126,760]	[439,322]	-2	hSpCas9	negative selection	260916
72572695	72572718	X	+	26472758	KBM7	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-0.11176171685502345	[326,240]	[154,92]	-1	hSpCas9	negative selection	260917
72572056	72572079	X	-	26472758	KBM7	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.032201152964041024	[649,807]	[410,306]	0	hSpCas9	negative selection	260918
72572676	72572699	X	+	26472758	KBM7	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.6302196904742454	[708,1212]	[344,261]	-5	hSpCas9	negative selection	260919
72568817	72568840	X	+	26472758	KBM7	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.2863645727177473	[743,396]	[106,309]	-3	hSpCas9	negative selection	260920
72567907	72567930	X	-	26472758	KBM7	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	0.33097070147667956	[634,411]	[268,335]	3	hSpCas9	negative selection	260921
72572746	72572769	X	-	26472758	Raji	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.0396389287377652	[108]	[25]	0	hSpCas9	negative selection	452030
72495205	72495228	X	-	26472758	Raji	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.0369942074822015	[125]	[29]	0	hSpCas9	negative selection	452031
72572730	72572753	X	-	26472758	Raji	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-1.352048083263698	[10]	[0]	-7	hSpCas9	negative selection	452032
72572651	72572674	X	+	26472758	Raji	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	1.455306838793906	[10]	[6]	9	hSpCas9	negative selection	452033
72572721	72572744	X	+	26472758	Raji	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	0.3528804955817304	[468]	[138]	3	hSpCas9	negative selection	452034
72572695	72572718	X	+	26472758	Raji	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	0.5318813639015094	[151]	[50]	5	hSpCas9	negative selection	452035
72572056	72572079	X	-	26472758	Raji	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	1.0976025145810142	[295]	[146]	8	hSpCas9	negative selection	452036
72572676	72572699	X	+	26472758	Raji	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	0.0935777358485691	[314]	[77]	0	hSpCas9	negative selection	452037
72568817	72568840	X	+	26472758	Raji	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.6581512109893776	[373]	[54]	-5	hSpCas9	negative selection	452038
72567907	72567930	X	-	26472758	Raji	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	0.43194028882157653	[328]	[102]	4	hSpCas9	negative selection	452039
72572746	72572769	X	-	26472758	K562	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.5049462778896661	[95]	[114]	4	hSpCas9	negative selection	643148
72495205	72495228	X	-	26472758	K562	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.23655660989347627	[183]	[182]	1	hSpCas9	negative selection	643149
72572730	72572753	X	-	26472758	K562	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	643150
72572651	72572674	X	+	26472758	K562	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	1.2133918320458223	[46]	[91]	8	hSpCas9	negative selection	643151
72572721	72572744	X	+	26472758	K562	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	0.3754182172004349	[767]	[840]	3	hSpCas9	negative selection	643152
72572695	72572718	X	+	26472758	K562	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	0.14384177291486935	[296]	[276]	1	hSpCas9	negative selection	643153
72572056	72572079	X	-	26472758	K562	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.1532217213778621	[576]	[437]	-1	hSpCas9	negative selection	643154
72572676	72572699	X	+	26472758	K562	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	0.30076958204781046	[476]	[495]	2	hSpCas9	negative selection	643155
72568817	72568840	X	+	26472758	K562	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.6365194156681317	[316]	[415]	5	hSpCas9	negative selection	643156
72567907	72567930	X	-	26472758	K562	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	0.04605999852965725	[505]	[440]	0	hSpCas9	negative selection	643157
72329673	72329696	X	-	26627737	DLD1	viability	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.5943191127324694	[609]	[96,137,141]	-5	hSpCas9	negative selection	846460
72462075	72462098	X	-	26627737	DLD1	viability	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.3876592722897019	[1138]	[442,550,414]	4	hSpCas9	negative selection	846461
72464622	72464645	X	-	26627737	DLD1	viability	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	0.6576126720037132	[354]	[166,255,114]	6	hSpCas9	negative selection	846462
72495155	72495178	X	-	26627737	DLD1	viability	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.03960347646189921	[584]	[167,221,149]	0	hSpCas9	negative selection	846464
72567974	72567997	X	-	26627737	DLD1	viability	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.05077365129016065	[758]	[259,238,238]	0	hSpCas9	negative selection	846467
72567975	72567998	X	-	26627737	DLD1	viability	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	0.7947110687169179	[121]	[92,30,71]	7	hSpCas9	negative selection	846468
72329673	72329696	X	-	26627737	GBM cells	viability after 5 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.035840100498875954	[280]	[138,154]	0	hSpCas9	negative selection	928775
72462075	72462098	X	-	26627737	GBM cells	viability after 5 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.34059614638244073	[683]	[491,436]	5	hSpCas9	negative selection	928776
72464622	72464645	X	-	26627737	GBM cells	viability after 5 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	0.5265972505914637	[243]	[172,203]	7	hSpCas9	negative selection	928777
72495155	72495178	X	-	26627737	GBM cells	viability after 5 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.025585678374114185	[315]	[162,181]	0	hSpCas9	negative selection	928779
72567974	72567997	X	-	26627737	GBM cells	viability after 5 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.28766007634560176	[442]	[281,297]	4	hSpCas9	negative selection	928782
72567975	72567998	X	-	26627737	GBM cells	viability after 5 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	0.07076890342639741	[165]	[87,98]	1	hSpCas9	negative selection	928783
72329673	72329696	X	-	26627737	GBM cells	viability after 13 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.039433477564597974	[280]	[165,133]	0	hSpCas9	negative selection	1011090
72462075	72462098	X	-	26627737	GBM cells	viability after 13 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.25176911509598465	[683]	[485,405]	3	hSpCas9	negative selection	1011091
72464622	72464645	X	-	26627737	GBM cells	viability after 13 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	0.682984307414511	[243]	[195,225]	8	hSpCas9	negative selection	1011092
72495155	72495178	X	-	26627737	GBM cells	viability after 13 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.36204285877615244	[315]	[253,192]	4	hSpCas9	negative selection	1011094
72567974	72567997	X	-	26627737	GBM cells	viability after 13 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.18159755259724786	[442]	[308,242]	2	hSpCas9	negative selection	1011097
72567975	72567998	X	-	26627737	GBM cells	viability after 13 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	0.42942946834929185	[165]	[85,149]	5	hSpCas9	negative selection	1011098
72329673	72329696	X	-	26627737	GBM cells	viability after 21 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.030834832163097792	[280]	[150,147]	0	hSpCas9	negative selection	1093405
72462075	72462098	X	-	26627737	GBM cells	viability after 21 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.31204651164532904	[683]	[476,446]	3	hSpCas9	negative selection	1093406
72464622	72464645	X	-	26627737	GBM cells	viability after 21 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	1.1433224514902853	[243]	[308,277]	9	hSpCas9	negative selection	1093407
72495155	72495178	X	-	26627737	GBM cells	viability after 21 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.21170712938587105	[315]	[214,183]	2	hSpCas9	negative selection	1093409
72567974	72567997	X	-	26627737	GBM cells	viability after 21 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.8024760205048985	[442]	[401,435]	7	hSpCas9	negative selection	1093412
72567975	72567998	X	-	26627737	GBM cells	viability after 21 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	1.633503310133778	[165]	[295,264]	9	hSpCas9	negative selection	1093413
72329673	72329696	X	-	26627737	RPE1	viability after 9 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-1.1579415577771686	[1167]	[131,204]	-7	hSpCas9	negative selection	1175720
72462075	72462098	X	-	26627737	RPE1	viability after 9 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.7218924101703759	[2247]	[1048,1304]	5	hSpCas9	negative selection	1175721
72464622	72464645	X	-	26627737	RPE1	viability after 9 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	2.1125225963191507	[225]	[322,283]	9	hSpCas9	negative selection	1175722
72495155	72495178	X	-	26627737	RPE1	viability after 9 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	1.465578418372567	[391]	[241,463]	7	hSpCas9	negative selection	1175724
72567974	72567997	X	-	26627737	RPE1	viability after 9 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.6356483084393268	[1070]	[392,685]	4	hSpCas9	negative selection	1175727
72567975	72567998	X	-	26627737	RPE1	viability after 9 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.10526038049074948	[600]	[256,68]	0	hSpCas9	negative selection	1175728
72329673	72329696	X	-	26627737	RPE1	viability after 12 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.692950661272645	[1167]	[197,189]	-5	hSpCas9	negative selection	1258035
72462075	72462098	X	-	26627737	RPE1	viability after 12 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.794950756707169	[2247]	[975,1123]	5	hSpCas9	negative selection	1258036
72464622	72464645	X	-	26627737	RPE1	viability after 12 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	1.9178337047176603	[225]	[226,231]	8	hSpCas9	negative selection	1258037
72495155	72495178	X	-	26627737	RPE1	viability after 12 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	1.1209653095092582	[391]	[213,244]	6	hSpCas9	negative selection	1258039
72567974	72567997	X	-	26627737	RPE1	viability after 12 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.577834981397971	[1070]	[258,609]	4	hSpCas9	negative selection	1258042
72567975	72567998	X	-	26627737	RPE1	viability after 12 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.10876639234509827	[600]	[157,140]	0	hSpCas9	negative selection	1258043
72329673	72329696	X	-	26627737	RPE1	viability after 15 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-1.3012315839308222	[1167]	[101,164]	-7	hSpCas9	negative selection	1340350
72462075	72462098	X	-	26627737	RPE1	viability after 15 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.8892690346469143	[2247]	[960,1386]	5	hSpCas9	negative selection	1340351
72464622	72464645	X	-	26627737	RPE1	viability after 15 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	1.99004897627365	[225]	[255,251]	8	hSpCas9	negative selection	1340352
72495155	72495178	X	-	26627737	RPE1	viability after 15 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	1.3641915973131202	[391]	[146,418]	7	hSpCas9	negative selection	1340354
72567974	72567997	X	-	26627737	RPE1	viability after 15 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.7667144182676152	[1070]	[320,702]	5	hSpCas9	negative selection	1340357
72567975	72567998	X	-	26627737	RPE1	viability after 15 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	0.5562989217000001	[600]	[221,276]	3	hSpCas9	negative selection	1340358
72329673	72329696	X	-	26627737	RPE1	viability after 18 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.5153819208418505	[1167]	[191,250]	-3	hSpCas9	negative selection	1422665
72462075	72462098	X	-	26627737	RPE1	viability after 18 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.7800402471205872	[2247]	[1019,1064]	5	hSpCas9	negative selection	1422666
72464622	72464645	X	-	26627737	RPE1	viability after 18 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	2.0689550255463938	[225]	[223,289]	8	hSpCas9	negative selection	1422667
72495155	72495178	X	-	26627737	RPE1	viability after 18 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	1.392447651895958	[391]	[254,301]	7	hSpCas9	negative selection	1422669
72567974	72567997	X	-	26627737	RPE1	viability after 18 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	1.034482804456668	[1070]	[228,979]	6	hSpCas9	negative selection	1422672
72567975	72567998	X	-	26627737	RPE1	viability after 18 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	0.2259256276750747	[600]	[165,214]	1	hSpCas9	negative selection	1422673
72329673	72329696	X	-	26627737	HeLa	viability after 8 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.06221045779165926	[459]	[180,396,53]	0	hSpCas9	negative selection	1504980
72462075	72462098	X	-	26627737	HeLa	viability after 8 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.44891909392196294	[864]	[709,678,216]	4	hSpCas9	negative selection	1504981
72464622	72464645	X	-	26627737	HeLa	viability after 8 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	0.19753729357551053	[402]	[237,121,247]	2	hSpCas9	negative selection	1504982
72495155	72495178	X	-	26627737	HeLa	viability after 8 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.39992190679445727	[569]	[179,235,148]	-4	hSpCas9	negative selection	1504984
72567974	72567997	X	-	26627737	HeLa	viability after 8 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.36325007850765423	[765]	[249,260,263]	-4	hSpCas9	negative selection	1504987
72567975	72567998	X	-	26627737	HeLa	viability after 8 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	1.513630247235081	[109]	[80,168,146]	9	hSpCas9	negative selection	1504988
72329673	72329696	X	-	26627737	HeLa	viability after 12 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.9198950985351776	[459]	[104,421,537]	7	hSpCas9	negative selection	1587295
72462075	72462098	X	-	26627737	HeLa	viability after 12 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.873891019913275	[864]	[810,464,713]	6	hSpCas9	negative selection	1587296
72464622	72464645	X	-	26627737	HeLa	viability after 12 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	0.1094202192038505	[402]	[68,54,424]	1	hSpCas9	negative selection	1587297
72495155	72495178	X	-	26627737	HeLa	viability after 12 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.168297282096255	[569]	[236,281,102]	-1	hSpCas9	negative selection	1587299
72567974	72567997	X	-	26627737	HeLa	viability after 12 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.07881202244235685	[765]	[413,247,245]	0	hSpCas9	negative selection	1587302
72567975	72567998	X	-	26627737	HeLa	viability after 12 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	1.8250754885825022	[109]	[221,160,101]	9	hSpCas9	negative selection	1587303
72329673	72329696	X	-	26627737	HeLa	viability after 15 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.3111875609912149	[459]	[199,161,343]	2	hSpCas9	negative selection	1669610
72462075	72462098	X	-	26627737	HeLa	viability after 15 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.288487661744667	[864]	[441,322,532]	2	hSpCas9	negative selection	1669611
72464622	72464645	X	-	26627737	HeLa	viability after 15 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.5638819168331722	[402]	[123,58,152]	-5	hSpCas9	negative selection	1669612
72495155	72495178	X	-	26627737	HeLa	viability after 15 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.7486510194218622	[569]	[106,129,180]	-6	hSpCas9	negative selection	1669614
72567974	72567997	X	-	26627737	HeLa	viability after 15 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.08116551906083269	[765]	[247,256,386]	0	hSpCas9	negative selection	1669617
72567975	72567998	X	-	26627737	HeLa	viability after 15 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	2.1123594052569152	[109]	[142,311,120]	9	hSpCas9	negative selection	1669618
72329673	72329696	X	-	26627737	HeLa	viability after 18 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.29544244545919585	[459]	[126,136,343]	2	hSpCas9	negative selection	1751925
72462075	72462098	X	-	26627737	HeLa	viability after 18 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.30677225672025354	[864]	[309,263,532]	2	hSpCas9	negative selection	1751926
72464622	72464645	X	-	26627737	HeLa	viability after 18 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.6161601695217844	[402]	[76,46,152]	-5	hSpCas9	negative selection	1751927
72495155	72495178	X	-	26627737	HeLa	viability after 18 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.7785398013252935	[569]	[65,107,180]	-6	hSpCas9	negative selection	1751929
72567974	72567997	X	-	26627737	HeLa	viability after 18 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.09187840997626562	[765]	[157,217,386]	-1	hSpCas9	negative selection	1751932
72567975	72567998	X	-	26627737	HeLa	viability after 18 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	2.067925790337664	[109]	[95,243,120]	9	hSpCas9	negative selection	1751933
72329673	72329696	X	-	26627737	HCT116	viability after 6 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.7347441746316469	[1182]	[70,440]	4	hSpCas9	negative selection	1834240
72462075	72462098	X	-	26627737	HCT116	viability after 6 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	-0.07658473197290205	[1447]	[347,142]	0	hSpCas9	negative selection	1834241
72464622	72464645	X	-	26627737	HCT116	viability after 6 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.2609901701098491	[787]	[94,107]	-1	hSpCas9	negative selection	1834242
72495155	72495178	X	-	26627737	HCT116	viability after 6 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.47755696731025044	[675]	[185,126]	2	hSpCas9	negative selection	1834244
72567974	72567997	X	-	26627737	HCT116	viability after 6 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.7698795689375034	[861]	[232,229]	4	hSpCas9	negative selection	1834247
72567975	72567998	X	-	26627737	HCT116	viability after 6 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	1.0820974753390264	[282]	[21,133]	6	hSpCas9	negative selection	1834248
72329673	72329696	X	-	26627737	HCT116	viability after 8 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.6133655765608077	[528]	[241,177,152]	-6	hSpCas9	negative selection	1916555
72462075	72462098	X	-	26627737	HCT116	viability after 8 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.159072862156737	[739]	[514,483,368]	1	hSpCas9	negative selection	1916556
72464622	72464645	X	-	26627737	HCT116	viability after 8 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.626851583258811	[446]	[161,192,123]	-6	hSpCas9	negative selection	1916557
72495155	72495178	X	-	26627737	HCT116	viability after 8 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.3098210384345504	[393]	[172,143,207]	-4	hSpCas9	negative selection	1916559
72567974	72567997	X	-	26627737	HCT116	viability after 8 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.12701730459281668	[707]	[344,325,399]	-1	hSpCas9	negative selection	1916562
72567975	72567998	X	-	26627737	HCT116	viability after 8 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	0.05209499267000883	[215]	[125,100,142]	0	hSpCas9	negative selection	1916563
72329673	72329696	X	-	26627737	HCT116	viability after 9 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.27720926321946593	[1182]	[274,467]	2	hSpCas9	negative selection	1998870
72462075	72462098	X	-	26627737	HCT116	viability after 9 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.7233304614490048	[1447]	[553,704]	5	hSpCas9	negative selection	1998871
72464622	72464645	X	-	26627737	HCT116	viability after 9 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.5079599623444118	[787]	[195,109]	-4	hSpCas9	negative selection	1998872
72495155	72495178	X	-	26627737	HCT116	viability after 9 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.3317527758478103	[675]	[105,172]	-2	hSpCas9	negative selection	1998874
72567974	72567997	X	-	26627737	HCT116	viability after 9 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.7523868231026497	[861]	[580,234]	5	hSpCas9	negative selection	1998877
72567975	72567998	X	-	26627737	HCT116	viability after 9 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	1.3222301090996014	[282]	[155,214]	8	hSpCas9	negative selection	1998878
72329673	72329696	X	-	26627737	HCT116	viability after 12 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.12632911454694407	[528]	[242,249,271]	-1	hSpCas9	negative selection	2081185
72462075	72462098	X	-	26627737	HCT116	viability after 12 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	-0.06711409196114415	[739]	[219,456,451]	0	hSpCas9	negative selection	2081186
72464622	72464645	X	-	26627737	HCT116	viability after 12 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.936128737157909	[446]	[89,155,125]	-7	hSpCas9	negative selection	2081187
72495155	72495178	X	-	26627737	HCT116	viability after 12 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.042424658293802486	[393]	[214,161,223]	0	hSpCas9	negative selection	2081189
72567974	72567997	X	-	26627737	HCT116	viability after 12 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.3396549026571981	[707]	[343,265,266]	-4	hSpCas9	negative selection	2081192
72567975	72567998	X	-	26627737	HCT116	viability after 12 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	0.03351488157091925	[215]	[74,191,86]	0	hSpCas9	negative selection	2081193
72329673	72329696	X	-	26627737	HCT116	viability after 15 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.291287546510269	[528]	[370,270,471]	3	hSpCas9	negative selection	2163500
72462075	72462098	X	-	26627737	HCT116	viability after 15 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	-0.06061276355322964	[739]	[353,456,404]	0	hSpCas9	negative selection	2163501
72464622	72464645	X	-	26627737	HCT116	viability after 15 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.9374945642107824	[446]	[182,167,57]	-7	hSpCas9	negative selection	2163502
72495155	72495178	X	-	26627737	HCT116	viability after 15 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.030531771240459027	[393]	[245,234,186]	0	hSpCas9	negative selection	2163504
72567974	72567997	X	-	26627737	HCT116	viability after 15 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.32436995463573093	[707]	[329,167,474]	-3	hSpCas9	negative selection	2163507
72567975	72567998	X	-	26627737	HCT116	viability after 15 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.22055083125825042	[215]	[133,103,84]	-2	hSpCas9	negative selection	2163508
72329673	72329696	X	-	26627737	HCT116	viability after 18 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.40081471943077307	[528]	[248,287,485]	3	hSpCas9	negative selection	2245815
72462075	72462098	X	-	26627737	HCT116	viability after 18 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	-0.12003031204796533	[739]	[380,389,206]	-1	hSpCas9	negative selection	2245816
72464622	72464645	X	-	26627737	HCT116	viability after 18 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-1.1113630859599355	[446]	[118,109,68]	-7	hSpCas9	negative selection	2245817
72495155	72495178	X	-	26627737	HCT116	viability after 18 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.10981101892859507	[393]	[201,220,191]	1	hSpCas9	negative selection	2245819
72567974	72567997	X	-	26627737	HCT116	viability after 18 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.6380703909115113	[707]	[191,169,304]	-5	hSpCas9	negative selection	2245822
72567975	72567998	X	-	26627737	HCT116	viability after 18 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.1874934250501527	[215]	[94,133,40]	-2	hSpCas9	negative selection	2245823
72572086	72572109	X	+	24336569	HL60	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-1.9584532105235528	[763]	[415]	-9	hSpCas9	negative selection	2269202
72572636	72572659	X	+	24336569	HL60	viability	CCCGACTTCCCTTACCCGTTTGG	HDAC8	ENSG00000147099	0.22206872630327934	[441]	[1090]	2	hSpCas9	negative selection	2269203
72572668	72572691	X	-	24336569	HL60	viability	TGTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.8935944441784989	[869]	[990]	-7	hSpCas9	negative selection	2269204
72572675	72572698	X	+	24336569	HL60	viability	GTCACACATACTGACATACTCGG	HDAC8	ENSG00000147099	1.3529671227460385	[253]	[1372]	8	hSpCas9	negative selection	2269205
72572694	72572717	X	+	24336569	HL60	viability	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	-0.17632328697033772	[109]	[205]	-1	hSpCas9	negative selection	2269206
72572713	72572736	X	-	24336569	HL60	viability	CAGTGGGCAGTCGCTGGTCCCGG	HDAC8	ENSG00000147099	0.21513469275732455	[1401]	[3443]	2	hSpCas9	negative selection	2269207
72572719	72572742	X	-	24336569	HL60	viability	GGCGGACAGTGGGCAGTCGCTGG	HDAC8	ENSG00000147099	0.39294002494456126	[243]	[677]	3	hSpCas9	negative selection	2269208
72572729	72572752	X	-	24336569	HL60	viability	CGGAGGAACCGGCGGACAGTGGG	HDAC8	ENSG00000147099	0.24929556122218705	[455]	[1146]	2	hSpCas9	negative selection	2269209
72572737	72572760	X	-	24336569	HL60	viability	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	-1.4060531769793267	[406]	[324]	-8	hSpCas9	negative selection	2269210
72572746	72572769	X	-	24336569	HL60	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.0019207938707645061	[520]	[1103]	0	hSpCas9	negative selection	2269211
72572086	72572109	X	+	24336569	KBM7	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.29617556327996264	[211]	[709]	2	hSpCas9	negative selection	2336379
72572636	72572659	X	+	24336569	KBM7	viability	CCCGACTTCCCTTACCCGTTTGG	HDAC8	ENSG00000147099	0.7292985655351967	[321]	[1455]	6	hSpCas9	negative selection	2336380
72572668	72572691	X	-	24336569	KBM7	viability	TGTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.6814251348551288	[684]	[1164]	-5	hSpCas9	negative selection	2336381
72572675	72572698	X	+	24336569	KBM7	viability	GTCACACATACTGACATACTCGG	HDAC8	ENSG00000147099	0.2840082178907569	[214]	[713]	2	hSpCas9	negative selection	2336382
72572694	72572717	X	+	24336569	KBM7	viability	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	0.7407884098468946	[189]	[865]	6	hSpCas9	negative selection	2336383
72572713	72572736	X	-	24336569	KBM7	viability	CAGTGGGCAGTCGCTGGTCCCGG	HDAC8	ENSG00000147099	-0.4543843744539968	[1274]	[2537]	-4	hSpCas9	negative selection	2336384
72572719	72572742	X	-	24336569	KBM7	viability	GGCGGACAGTGGGCAGTCGCTGG	HDAC8	ENSG00000147099	0.05532328894203753	[210]	[597]	0	hSpCas9	negative selection	2336385
72572729	72572752	X	-	24336569	KBM7	viability	CGGAGGAACCGGCGGACAGTGGG	HDAC8	ENSG00000147099	0.027548752566290635	[481]	[1339]	0	hSpCas9	negative selection	2336386
72572737	72572760	X	-	24336569	KBM7	viability	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	-3.0001202195776613	[439]	[149]	-9	hSpCas9	negative selection	2336387
72572746	72572769	X	-	24336569	KBM7	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-0.0813888014854773	[397]	[1025]	0	hSpCas9	negative selection	2336388
72441078	72441101	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCTGTAGGCTCCACCTCCGG	HDAC8	ENSG00000147099	0.22284639033454834	[76,251]	[35,48]	1	dCas9-VP64	positive selection	2384669
72441078	72441101	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCTGTAGGCTCCACCTCCGG	HDAC8	ENSG00000147099	-0.3137172453886481	[73,192]	[24,43]	-3	dCas9-VP64	positive selection	2479924
72572722	72572745	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.1331314309196962	[2,2]	[1,1]	-2	hSpCas9	positive selection	2992892
72572651	72572674	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.16077616578348441	[2,2]	[3,2]	3	hSpCas9	positive selection	2992893
72572737	72572760	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	-1.1288774636444152	[2,2]	[0,0]	-9	hSpCas9	positive selection	2992894
72572695	72572718	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	-0.502375925642388	[3,3]	[2,1]	-6	hSpCas9	positive selection	2992895
72572722	72572745	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	0.0418845022732075	[2,2]	[2,1]	0	hSpCas9	positive selection	3060750
72572651	72572674	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.19940952446012025	[2,2]	[2,1]	3	hSpCas9	positive selection	3060751
72572737	72572760	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	-0.20018320595459188	[2,2]	[2,0]	-3	hSpCas9	positive selection	3060752
72572695	72572718	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	-1.1151605132747306	[3,3]	[1,0]	-9	hSpCas9	positive selection	3060753
72572086	72572109		+	24336571	A375	resistance to PLX after 7 days	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.04165007671316756	[71,78]	[74,70]	-1	hSpCas9	positive selection	3118636
72568778	72568801		+	24336571	A375	resistance to PLX after 7 days	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.011933698270471638	[86,77]	[87,77]	0	hSpCas9	positive selection	3118637
72495207	72495230		+	24336571	A375	resistance to PLX after 7 days	GTCGCAATCGTAATATTCCCAGG	HDAC8	ENSG00000147099	0.22783261155366663	[21,23]	[29,22]	6	hSpCas9	positive selection	3118638
72568865	72568888		-	24336571	A375	resistance to PLX after 7 days	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.37967879470821425	[12,14]	[19,16]	8	hSpCas9	positive selection	3118639
72572086	72572109		+	24336571	A375	resistance to PLX after 14 days	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.22823714397870054	[69,77]	[27,30]	-2	hSpCas9	positive selection	3176429
72568778	72568801		+	24336571	A375	resistance to PLX after 14 days	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	-0.3621017151972845	[84,92]	[32,30]	-4	hSpCas9	positive selection	3176430
72495207	72495230		+	24336571	A375	resistance to PLX after 14 days	GTCGCAATCGTAATATTCCCAGG	HDAC8	ENSG00000147099	0.15247226781910972	[21,18]	[10,8]	1	hSpCas9	positive selection	3176431
72568865	72568888		-	24336571	A375	resistance to PLX after 14 days	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	1.288311578925259	[12,14]	[16,13]	8	hSpCas9	positive selection	3176432
72572086	72572109		+	24336571	A375	viability after 7 days	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.1931108167185802	[90]	[71,78]	-3	hSpCas9	negative selection	3234222
72568778	72568801		+	24336571	A375	viability after 7 days	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5914329774187199	[57]	[86,77]	8	hSpCas9	negative selection	3234223
72495207	72495230		+	24336571	A375	viability after 7 days	GTCGCAATCGTAATATTCCCAGG	HDAC8	ENSG00000147099	-0.6925378833164808	[38]	[21,23]	-7	hSpCas9	negative selection	3234224
72568865	72568888		-	24336571	A375	viability after 7 days	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.12821466435035445	[13]	[12,14]	2	hSpCas9	negative selection	3234225
72572086	72572109		+	24336571	A375	viability after 14 days	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.20655547967749266	[90]	[69,77]	-2	hSpCas9	negative selection	3292015
72568778	72568801		+	24336571	A375	viability after 14 days	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.7080596974767839	[57]	[84,92]	8	hSpCas9	negative selection	3292016
72495207	72495230		+	24336571	A375	viability after 14 days	GTCGCAATCGTAATATTCCCAGG	HDAC8	ENSG00000147099	-0.8351548608367944	[38]	[21,18]	-8	hSpCas9	negative selection	3292017
72568865	72568888		-	24336571	A375	viability after 14 days	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.08963451197285315	[13]	[12,14]	1	hSpCas9	negative selection	3292018
72567929	72567952	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	-2.027940000341989	[690,555]	[0,0]	-9	hSpCas9	positive selection	3353129
72568778	72568801	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	-1.4697711615880593	[386,460]	[0,0]	-8	hSpCas9	positive selection	3353130
72567940	72567963	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.9345958276488086	[280,303]	[0,0]	-6	hSpCas9	positive selection	3353131
72568865	72568888	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.6723637107246789	[95,95]	[0,0]	3	hSpCas9	positive selection	3372322
72572086	72572109	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.09745487466744575	[142,142]	[0,0]	0	hSpCas9	positive selection	3372323
72572056	72572079	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.08740121000352279	[143,143]	[0,0]	0	hSpCas9	positive selection	3372324
72572721	72572744	X	+	26780180	HT29	viability (Avana library 4 designs)	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	3.35287237339173	[]	[]	8	hSpCas9	negative selection	3430153
72572651	72572674	X	-	26780180	HT29	viability (Avana library 4 designs)	CCCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	1.94109015463205	[]	[]	7	hSpCas9	negative selection	3430154
72572737	72572760	X	-	26780180	HT29	viability (Avana library 4 designs)	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	4.52670146000843	[]	[]	9	hSpCas9	negative selection	3430155
72572694	72572717	X	+	26780180	HT29	viability (Avana library 4 designs)	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	2.21685132301964	[]	[]	7	hSpCas9	negative selection	3430156
72572737	72572760	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	-3.7771132797176	[]	[]	-4	hSpCas9	negative selection	3515173
72572651	72572674	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	5.46191263455672	[]	[]	8	hSpCas9	negative selection	3515174
72572721	72572744	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	3.39601972112972	[]	[]	5	hSpCas9	negative selection	3515175
72572694	72572717	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	-15.4429760869917	[]	[]	-9	hSpCas9	negative selection	3515176
72572651	72572674	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	3.16074881845553	[]	[]	5	hSpCas9	negative selection	3515177
72572650	72572673	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGCCAAGATCCCCAAACGGG	HDAC8	ENSG00000147099	1.43191415363917	[]	[]	2	hSpCas9	negative selection	3515178
72572737	72572760	X	-	26780180	A375	viability (Avana lentiGuide)	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	16.375880632244	[]	[]	8	hSpCas9	negative selection	3623832
72572651	72572674	X	-	26780180	A375	viability (Avana lentiGuide)	CCCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	-0.948270231750017	[]	[]	-1	hSpCas9	negative selection	3623833
72572721	72572744	X	+	26780180	A375	viability (Avana lentiGuide)	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-4.72807967777389	[]	[]	-7	hSpCas9	negative selection	3623834
72572694	72572717	X	+	26780180	A375	viability (Avana lentiGuide)	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	-0.607687728668326	[]	[]	-1	hSpCas9	negative selection	3623835
72572651	72572674	X	+	26780180	A375	viability (Avana lentiGuide)	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-2.81029028955955	[]	[]	-5	hSpCas9	negative selection	3623836
72572650	72572673	X	-	26780180	A375	viability (Avana lentiGuide)	CCTGGCCAAGATCCCCAAACGGG	HDAC8	ENSG00000147099	-0.144035062018547	[]	[]	0	hSpCas9	negative selection	3623837
72572737	72572760	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	-0.5106379907485197	[3]	[3,1]	-6	hSpCas9	positive selection	3732491
72572651	72572674	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.28893435007681084	[4]	[6,4]	8	hSpCas9	positive selection	3732492
72572721	72572744	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	0.13126764599559004	[3]	[5,3]	3	hSpCas9	positive selection	3732493
72572694	72572717	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	-1.0138012682400972	[6]	[2,2]	-8	hSpCas9	positive selection	3732494
72572651	72572674	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	0.3434010070350546	[4]	[5,5]	8	hSpCas9	positive selection	3732495
72572650	72572673	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGCCAAGATCCCCAAACGGG	HDAC8	ENSG00000147099	0.05587487602735747	[3]	[4,3]	1	hSpCas9	positive selection	3732496
72572737	72572760	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGAGCCGGAGGAACCGGCGG	HDAC8	ENSG00000147099	-1.0441297739591442	[4]	[0,1]	-8	hSpCas9	positive selection	3841098
72572651	72572674	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	-0.19776860280498504	[4]	[3,3]	-3	hSpCas9	positive selection	3841099
72572721	72572744	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.6044951087573653	[4]	[1,2]	-6	hSpCas9	positive selection	3841100
72572694	72572717	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGGGACTATAGATATAAACCGG	HDAC8	ENSG00000147099	0.3983220787077463	[5]	[5,5]	9	hSpCas9	positive selection	3841101
72572651	72572674	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	0.30585455484890367	[5]	[5,5]	8	hSpCas9	positive selection	3841102
72572650	72572673	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGCCAAGATCCCCAAACGGG	HDAC8	ENSG00000147099	0.07695422426552505	[4]	[5,2]	1	hSpCas9	positive selection	3841103
72572086	72572109	X	+	26780180	A375	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	1.5053801807844	[]	[]	8	hSpCas9	negative selection	3947168
72572056	72572079	X	-	26780180	A375	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.834310619041754	[]	[]	3	hSpCas9	negative selection	3947169
72567929	72567952	X	+	26780180	A375	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	-0.271230464605296	[]	[]	-7	hSpCas9	negative selection	3947170
72568778	72568801	X	+	26780180	A375	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	-0.45935715990819	[]	[]	-9	hSpCas9	negative selection	3947171
72567940	72567963	X	-	26780180	A375	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.447425779511122	[]	[]	1	hSpCas9	negative selection	3947172
72568865	72568888	X	-	26780180	A375	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.959110565762461	[]	[]	4	hSpCas9	negative selection	3947173
72572086	72572109	X	+	26780180	HT29	viability (GeCKOv2 library)	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	2.00266380228952	[]	[]	9	hSpCas9	negative selection	4055134
72572056	72572079	X	-	26780180	HT29	viability (GeCKOv2 library)	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	1.25681980276264	[]	[]	6	hSpCas9	negative selection	4055135
72567929	72567952	X	+	26780180	HT29	viability (GeCKOv2 library)	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.158913075164494	[]	[]	0	hSpCas9	negative selection	4055136
72568778	72568801	X	+	26780180	HT29	viability (GeCKOv2 library)	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	-0.403287675322693	[]	[]	-8	hSpCas9	negative selection	4055137
72567940	72567963	X	-	26780180	HT29	viability (GeCKOv2 library)	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.562505189820453	[]	[]	2	hSpCas9	negative selection	4055138
72568865	72568888	X	-	26780180	HT29	viability (GeCKOv2 library)	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	2.25500834750175	[]	[]	9	hSpCas9	negative selection	4055139
72572086	72572109	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.14194066720815357	[6]	[4,4]	3	hSpCas9	positive selection	4142073
72568778	72568801	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.1631737061965839	[6]	[4,4]	4	hSpCas9	positive selection	4142074
72495207	72495230	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCGCAATCGTAATATTCCCAGG	HDAC8	ENSG00000147099	0.15937214680889708	[4]	[3,3]	4	hSpCas9	positive selection	4142075
72568865	72568888	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.007162510241118497	[4]	[1,3]	0	hSpCas9	positive selection	4142076
72572086	72572109	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	1.045914772329618	[6]	[5,5,6,5]	7	hSpCas9	positive selection	4206095
72568778	72568801	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	1.0404708689701994	[6]	[6,5,5,5]	7	hSpCas9	positive selection	4206096
72495207	72495230	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCGCAATCGTAATATTCCCAGG	HDAC8	ENSG00000147099	0.8682568946267071	[4]	[3,4,2,3]	6	hSpCas9	positive selection	4206097
72568865	72568888	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	1.3171996368920869	[4]	[3,3,4,5]	9	hSpCas9	positive selection	4206098
72567929	72567952	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.3889949771230269	[4]	[5,4]	7	hSpCas9	positive selection	4274703
72568778	72568801	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.4766148309696174	[4]	[4,4]	8	hSpCas9	positive selection	4274704
72567940	72567963	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.5501428027998548	[4]	[5,4]	9	hSpCas9	positive selection	4274705
72568865	72568888	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.19488869616493676	[2]	[2,0]	-4	hSpCas9	positive selection	4338964
72572086	72572109	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.11388134793658758	[3]	[2,2]	2	hSpCas9	positive selection	4338965
72572056	72572079	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.41826057089976776	[3]	[3,3]	8	hSpCas9	positive selection	4338966
72572651	72572673	X	-	27760321	OCIAML3	viability	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.056842617480122426	[219,169]	[107,221]	0	hSpCas9	negative selection	4406429
72572668	72572690	X	-	27760321	OCIAML3	viability	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-1.0326487562030437	[925,766]	[352,281]	-7	hSpCas9	negative selection	4406430
72495180	72495202	X	-	27760321	OCIAML3	viability	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-0.05379412981189402	[182,136]	[122,114]	0	hSpCas9	negative selection	4406431
72495205	72495227	X	-	27760321	OCIAML3	viability	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.33278994200615764	[355,324]	[127,319]	-3	hSpCas9	negative selection	4406432
72495254	72495276	X	-	27760321	OCIAML3	viability	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-0.09592966645079315	[157,183]	[111,144]	-1	hSpCas9	negative selection	4406433
72568759	72568781	X	-	27760321	OCIAML3	viability	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	-0.9587409117901786	[134,83]	[25,65]	-7	hSpCas9	negative selection	4406434
72568818	72568840	X	+	27760321	OCIAML3	viability	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.9339737143177842	[497,401]	[200,159]	-7	hSpCas9	negative selection	4406435
72568856	72568878	X	-	27760321	OCIAML3	viability	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	-0.4919862423349496	[488,514]	[182,407]	-5	hSpCas9	negative selection	4406436
72572056	72572078	X	-	27760321	OCIAML3	viability	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.0850042618220529	[382,310]	[168,365]	-1	hSpCas9	negative selection	4406437
72572087	72572109	X	+	27760321	OCIAML3	viability	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-1.4244021189286207	[141,83]	[27,37]	-8	hSpCas9	negative selection	4406438
72572651	72572673	X	-	27760321	OCIAML2	viability	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.04819205370538371	[219,169]	[151,174]	0	hSpCas9	negative selection	4489892
72572668	72572690	X	-	27760321	OCIAML2	viability	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.38087874980105196	[925,766]	[523,522]	-4	hSpCas9	negative selection	4489893
72495180	72495202	X	-	27760321	OCIAML2	viability	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-0.6791901729331646	[182,136]	[58,107]	-6	hSpCas9	negative selection	4489894
72495205	72495227	X	-	27760321	OCIAML2	viability	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.20290151212483173	[355,324]	[309,325]	2	hSpCas9	negative selection	4489895
72495254	72495276	X	-	27760321	OCIAML2	viability	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	0.4710262686893548	[157,183]	[193,192]	6	hSpCas9	negative selection	4489896
72568759	72568781	X	-	27760321	OCIAML2	viability	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	-1.5006228062923013	[134,83]	[16,48]	-8	hSpCas9	negative selection	4489897
72568818	72568840	X	+	27760321	OCIAML2	viability	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.01662125992017566	[497,401]	[310,438]	0	hSpCas9	negative selection	4489898
72568856	72568878	X	-	27760321	OCIAML2	viability	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	0.4991209647142115	[488,514]	[504,671]	6	hSpCas9	negative selection	4489899
72572056	72572078	X	-	27760321	OCIAML2	viability	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.16054276602622863	[382,310]	[169,354]	-2	hSpCas9	negative selection	4489900
72572087	72572109	X	+	27760321	OCIAML2	viability	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.02989170735455926	[141,83]	[74,104]	0	hSpCas9	negative selection	4489901
72572651	72572673	X	-	27760321	MV411	viability	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	-0.9888190754606818	[219,169]	[29,115]	-6	hSpCas9	negative selection	4573355
72572668	72572690	X	-	27760321	MV411	viability	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	0.058977175455202535	[925,766]	[265,1049]	0	hSpCas9	negative selection	4573356
72495180	72495202	X	-	27760321	MV411	viability	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-2.924077634862244	[182,136]	[4,26]	-9	hSpCas9	negative selection	4573357
72495205	72495227	X	-	27760321	MV411	viability	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	2.064151192971522	[355,324]	[1212,527]	9	hSpCas9	negative selection	4573358
72495254	72495276	X	-	27760321	MV411	viability	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	0.6178017860242192	[157,183]	[187,154]	4	hSpCas9	negative selection	4573359
72568759	72568781	X	-	27760321	MV411	viability	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	-1.6935235008321943	[134,83]	[5,45]	-8	hSpCas9	negative selection	4573360
72568818	72568840	X	+	27760321	MV411	viability	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-1.592502523649655	[497,401]	[13,223]	-7	hSpCas9	negative selection	4573361
72568856	72568878	X	-	27760321	MV411	viability	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	-0.15431924091461355	[488,514]	[148,524]	-1	hSpCas9	negative selection	4573362
72572056	72572078	X	-	27760321	MV411	viability	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-1.3498292182106473	[382,310]	[52,143]	-7	hSpCas9	negative selection	4573363
72572087	72572109	X	+	27760321	MV411	viability	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-1.8728063194143416	[141,83]	[17,22]	-8	hSpCas9	negative selection	4573364
72572651	72572673	X	-	27760321	HL60	viability	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	-1.1175315056615933	[219,169]	[68,76]	-8	hSpCas9	negative selection	4656818
72572668	72572690	X	-	27760321	HL60	viability	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.23040550757366796	[925,766]	[563,610]	-3	hSpCas9	negative selection	4656819
72495180	72495202	X	-	27760321	HL60	viability	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-1.0108183848395178	[182,136]	[57,70]	-7	hSpCas9	negative selection	4656820
72495205	72495227	X	-	27760321	HL60	viability	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.07891784520239004	[355,324]	[248,340]	1	hSpCas9	negative selection	4656821
72495254	72495276	X	-	27760321	HL60	viability	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-0.3262877029440223	[157,183]	[94,130]	-4	hSpCas9	negative selection	4656822
72568759	72568781	X	-	27760321	HL60	viability	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	-0.524771461174915	[134,83]	[83,36]	-5	hSpCas9	negative selection	4656823
72568818	72568840	X	+	27760321	HL60	viability	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.13218179666507818	[497,401]	[405,394]	1	hSpCas9	negative selection	4656824
72568856	72568878	X	-	27760321	HL60	viability	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	0.5026675233919647	[488,514]	[472,701]	6	hSpCas9	negative selection	4656825
72572056	72572078	X	-	27760321	HL60	viability	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.22544918935415825	[382,310]	[213,269]	-3	hSpCas9	negative selection	4656826
72572087	72572109	X	+	27760321	HL60	viability	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.36263394491756107	[141,83]	[70,69]	-4	hSpCas9	negative selection	4656827
72572651	72572673	X	-	27760321	HT1080	viability	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	2.7007390337181505	[169,132]	[369,416]	9	hSpCas9	negative selection	4740281
72572668	72572690	X	-	27760321	HT1080	viability	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.28584288371534106	[766,598]	[300,137]	-1	hSpCas9	negative selection	4740282
72495180	72495202	X	-	27760321	HT1080	viability	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	1.8494902966527789	[136,106]	[209,136]	8	hSpCas9	negative selection	4740283
72495205	72495227	X	-	27760321	HT1080	viability	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	2.0608990604497666	[324,253]	[380,590]	9	hSpCas9	negative selection	4740284
72495254	72495276	X	-	27760321	HT1080	viability	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-2.564619871888519	[183,143]	[11,9]	-7	hSpCas9	negative selection	4740285
72568759	72568781	X	-	27760321	HT1080	viability	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	3.876327759636344	[83,65]	[574,289]	9	hSpCas9	negative selection	4740286
72568818	72568840	X	+	27760321	HT1080	viability	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.6487182346764904	[401,313]	[121,56]	-3	hSpCas9	negative selection	4740287
72568856	72568878	X	-	27760321	HT1080	viability	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	1.5248163784104798	[514,401]	[400,661]	8	hSpCas9	negative selection	4740288
72572056	72572078	X	-	27760321	HT1080	viability	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	1.965085921928718	[310,242]	[385,479]	9	hSpCas9	negative selection	4740289
72572087	72572109	X	+	27760321	HT1080	viability	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	4.019939829035468	[83,65]	[545,417]	9	hSpCas9	negative selection	4740290
72572651	72572673	X	-	27760321	HT29	viability after 7 days	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.7783637585015153	[169,132]	[503,309,215]	9	hSpCas9	negative selection	4823744
72572668	72572690	X	-	27760321	HT29	viability after 7 days	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	0.1855699772244691	[766,598]	[1252,970,812]	3	hSpCas9	negative selection	4823745
72495180	72495202	X	-	27760321	HT29	viability after 7 days	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-1.6654846214002896	[136,106]	[26,97,20]	-9	hSpCas9	negative selection	4823746
72495205	72495227	X	-	27760321	HT29	viability after 7 days	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.8321775213073991	[324,253]	[171,314,136]	-8	hSpCas9	negative selection	4823747
72495254	72495276	X	-	27760321	HT29	viability after 7 days	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-0.2500472566357741	[183,143]	[238,138,162]	-4	hSpCas9	negative selection	4823748
72568759	72568781	X	-	27760321	HT29	viability after 7 days	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	0.8054978472954706	[83,65]	[202,123,182]	9	hSpCas9	negative selection	4823749
72568818	72568840	X	+	27760321	HT29	viability after 7 days	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.4071296938286563	[401,313]	[872,551,447]	6	hSpCas9	negative selection	4823750
72568856	72568878	X	-	27760321	HT29	viability after 7 days	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	0.22865922459114973	[514,401]	[803,897,394]	3	hSpCas9	negative selection	4823751
72572056	72572078	X	-	27760321	HT29	viability after 7 days	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.05865457950625047	[310,242]	[591,281,272]	0	hSpCas9	negative selection	4823752
72572087	72572109	X	+	27760321	HT29	viability after 7 days	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.48805493450002646	[83,65]	[190,161,62]	7	hSpCas9	negative selection	4823753
72572651	72572673	X	-	27760321	HT29	viability after 25 days	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.4922796468579922	[169,132]	[157,314,264]	5	hSpCas9	negative selection	4907207
72572668	72572690	X	-	27760321	HT29	viability after 25 days	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.4269387319237787	[766,598]	[501,412,859]	-4	hSpCas9	negative selection	4907208
72495180	72495202	X	-	27760321	HT29	viability after 25 days	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-1.2358016598669752	[136,106]	[67,14,97]	-7	hSpCas9	negative selection	4907209
72495205	72495227	X	-	27760321	HT29	viability after 25 days	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.8121719433270717	[324,253]	[142,226,198]	-6	hSpCas9	negative selection	4907210
72495254	72495276	X	-	27760321	HT29	viability after 25 days	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-0.5766554968866673	[183,143]	[194,107,62]	-5	hSpCas9	negative selection	4907211
72568759	72568781	X	-	27760321	HT29	viability after 25 days	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	0.6845439004323652	[83,65]	[203,84,117]	7	hSpCas9	negative selection	4907212
72568818	72568840	X	+	27760321	HT29	viability after 25 days	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.18109401657134036	[401,313]	[326,363,396]	-2	hSpCas9	negative selection	4907213
72568856	72568878	X	-	27760321	HT29	viability after 25 days	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	-0.3299692319984997	[514,401]	[431,425,387]	-3	hSpCas9	negative selection	4907214
72572056	72572078	X	-	27760321	HT29	viability after 25 days	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.9279668299374262	[310,242]	[227,126,136]	-6	hSpCas9	negative selection	4907215
72572087	72572109	X	+	27760321	HT29	viability after 25 days	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.8379870159575615	[83,65]	[106,11,17]	-6	hSpCas9	negative selection	4907216
72572651	72572673	X	-	27760321	HT29	viability after 22 days	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.3412828421633518	[169,132]	[301,199,160]	3	hSpCas9	negative selection	4990670
72572668	72572690	X	-	27760321	HT29	viability after 22 days	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.7659044001303503	[766,598]	[329,360,707]	-6	hSpCas9	negative selection	4990671
72495180	72495202	X	-	27760321	HT29	viability after 22 days	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-1.0034850230484147	[136,106]	[111,19,77]	-6	hSpCas9	negative selection	4990672
72495205	72495227	X	-	27760321	HT29	viability after 22 days	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.8615463692474973	[324,253]	[57,316,180]	-6	hSpCas9	negative selection	4990673
72495254	72495276	X	-	27760321	HT29	viability after 22 days	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-1.5234008286286362	[183,143]	[27,95,74]	-7	hSpCas9	negative selection	4990674
72568759	72568781	X	-	27760321	HT29	viability after 22 days	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	-0.1030134989516216	[83,65]	[30,92,119]	-1	hSpCas9	negative selection	4990675
72568818	72568840	X	+	27760321	HT29	viability after 22 days	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.24923214004833794	[401,313]	[486,194,358]	-3	hSpCas9	negative selection	4990676
72568856	72568878	X	-	27760321	HT29	viability after 22 days	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	-0.49669058644433844	[514,401]	[487,358,275]	-4	hSpCas9	negative selection	4990677
72572056	72572078	X	-	27760321	HT29	viability after 22 days	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.7478550317474701	[310,242]	[170,172,228]	-6	hSpCas9	negative selection	4990678
72572087	72572109	X	+	27760321	HT29	viability after 22 days	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.1327214119140101	[83,65]	[94,53,87]	-1	hSpCas9	negative selection	4990679
72572651	72572673	X	-	27760321	HT29	viability after 19 days	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	-0.09135213550203547	[169,132]	[146,223,116]	-1	hSpCas9	negative selection	5074133
72572668	72572690	X	-	27760321	HT29	viability after 19 days	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.10680838514477764	[766,598]	[691,854,628]	-1	hSpCas9	negative selection	5074134
72495180	72495202	X	-	27760321	HT29	viability after 19 days	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-0.10932949759669564	[136,106]	[101,16,260]	-1	hSpCas9	negative selection	5074135
72495205	72495227	X	-	27760321	HT29	viability after 19 days	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.24800734390100998	[324,253]	[99,503,215]	-2	hSpCas9	negative selection	5074136
72495254	72495276	X	-	27760321	HT29	viability after 19 days	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-2.129874278495021	[183,143]	[128,3,5]	-8	hSpCas9	negative selection	5074137
72568759	72568781	X	-	27760321	HT29	viability after 19 days	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	-0.4163231570402588	[83,65]	[110,55,31]	-4	hSpCas9	negative selection	5074138
72568818	72568840	X	+	27760321	HT29	viability after 19 days	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.27050202050499594	[401,313]	[368,436,655]	2	hSpCas9	negative selection	5074139
72568856	72568878	X	-	27760321	HT29	viability after 19 days	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	-0.04372624308880446	[514,401]	[370,700,441]	0	hSpCas9	negative selection	5074140
72572056	72572078	X	-	27760321	HT29	viability after 19 days	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.6141196532647815	[310,242]	[285,79,260]	-5	hSpCas9	negative selection	5074141
72572087	72572109	X	+	27760321	HT29	viability after 19 days	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.304506892679824	[83,65]	[145,41,132]	3	hSpCas9	negative selection	5074142
72572651	72572673	X	-	27760321	HT29	viability after 16 days	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.495466110155628	[169,132]	[213,260,238]	5	hSpCas9	negative selection	5157596
72572668	72572690	X	-	27760321	HT29	viability after 16 days	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	0.22342693635340394	[766,598]	[794,899,971]	2	hSpCas9	negative selection	5157597
72495180	72495202	X	-	27760321	HT29	viability after 16 days	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-0.8994069035031127	[136,106]	[27,82,103]	-6	hSpCas9	negative selection	5157598
72495205	72495227	X	-	27760321	HT29	viability after 16 days	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.3032697173731729	[324,253]	[228,159,397]	-3	hSpCas9	negative selection	5157599
72495254	72495276	X	-	27760321	HT29	viability after 16 days	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-0.8072987223786372	[183,143]	[52,207,45]	-6	hSpCas9	negative selection	5157600
72568759	72568781	X	-	27760321	HT29	viability after 16 days	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	0.858417791870945	[83,65]	[126,120,206]	8	hSpCas9	negative selection	5157601
72568818	72568840	X	+	27760321	HT29	viability after 16 days	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.15587305207764476	[401,313]	[400,261,421]	-2	hSpCas9	negative selection	5157602
72568856	72568878	X	-	27760321	HT29	viability after 16 days	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	-0.1923256845727351	[514,401]	[608,253,503]	-2	hSpCas9	negative selection	5157603
72572056	72572078	X	-	27760321	HT29	viability after 16 days	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.2689876252007424	[310,242]	[337,150,292]	-3	hSpCas9	negative selection	5157604
72572087	72572109	X	+	27760321	HT29	viability after 16 days	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.37331904010400896	[83,65]	[134,27,38]	-4	hSpCas9	negative selection	5157605
72572651	72572673	X	-	27760321	HT29	viability after 13 days	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	1.3368179826057063	[169,132]	[790,229,317]	9	hSpCas9	negative selection	5241059
72572668	72572690	X	-	27760321	HT29	viability after 13 days	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.026594948483095626	[766,598]	[782,796,754]	0	hSpCas9	negative selection	5241060
72495180	72495202	X	-	27760321	HT29	viability after 13 days	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-1.2724790521637264	[136,106]	[103,18,52]	-8	hSpCas9	negative selection	5241061
72495205	72495227	X	-	27760321	HT29	viability after 13 days	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.28620667223780694	[324,253]	[111,376,333]	-4	hSpCas9	negative selection	5241062
72495254	72495276	X	-	27760321	HT29	viability after 13 days	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-0.9807298767743149	[183,143]	[60,57,165]	-7	hSpCas9	negative selection	5241063
72568759	72568781	X	-	27760321	HT29	viability after 13 days	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	-0.5423180655654307	[83,65]	[75,21,79]	-6	hSpCas9	negative selection	5241064
72568818	72568840	X	+	27760321	HT29	viability after 13 days	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.0921118413026144	[401,313]	[475,306,538]	1	hSpCas9	negative selection	5241065
72568856	72568878	X	-	27760321	HT29	viability after 13 days	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	-0.1972101247139154	[514,401]	[552,364,472]	-2	hSpCas9	negative selection	5241066
72572056	72572078	X	-	27760321	HT29	viability after 13 days	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.23672163878689667	[310,242]	[437,178,204]	-3	hSpCas9	negative selection	5241067
72572087	72572109	X	+	27760321	HT29	viability after 13 days	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.5955496767801938	[83,65]	[191,148,57]	7	hSpCas9	negative selection	5241068
72572651	72572673	X	-	27760321	HT29	viability after 10 days	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.2631019028334014	[169,132]	[244,297,141]	3	hSpCas9	negative selection	5324522
72572668	72572690	X	-	27760321	HT29	viability after 10 days	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	-0.030601644164656383	[766,598]	[533,797,1163]	0	hSpCas9	negative selection	5324523
72495180	72495202	X	-	27760321	HT29	viability after 10 days	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	-0.9852880404953468	[136,106]	[48,112,69]	-8	hSpCas9	negative selection	5324524
72495205	72495227	X	-	27760321	HT29	viability after 10 days	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.7557349367045582	[324,253]	[217,347,82]	-7	hSpCas9	negative selection	5324525
72495254	72495276	X	-	27760321	HT29	viability after 10 days	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	-0.8754129508063608	[183,143]	[126,86,119]	-7	hSpCas9	negative selection	5324526
72568759	72568781	X	-	27760321	HT29	viability after 10 days	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	0.3528369769625739	[83,65]	[118,61,174]	5	hSpCas9	negative selection	5324527
72568818	72568840	X	+	27760321	HT29	viability after 10 days	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.007004977648241741	[401,313]	[528,363,451]	0	hSpCas9	negative selection	5324528
72568856	72568878	X	-	27760321	HT29	viability after 10 days	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	0.04794463542636879	[514,401]	[586,506,676]	0	hSpCas9	negative selection	5324529
72572056	72572078	X	-	27760321	HT29	viability after 10 days	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.2810365249518556	[310,242]	[251,320,281]	-4	hSpCas9	negative selection	5324530
72572087	72572109	X	+	27760321	HT29	viability after 10 days	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.09063946666990841	[83,65]	[145,33,116]	1	hSpCas9	negative selection	5324531
72572651	72572673	X	-	27760321	MOLM13	viability	CCTGGCCAAGATCCCCAAACGG	HDAC8	ENSG00000147099	0.08754322834647521	[219,169]	[0,213]	0	hSpCas9	negative selection	5407985
72572668	72572690	X	-	27760321	MOLM13	viability	GTCAGTATGTGTGACTCCCTGG	HDAC8	ENSG00000147099	0.8685491068877217	[925,766]	[1679,176]	6	hSpCas9	negative selection	5407986
72495180	72495202	X	-	27760321	MOLM13	viability	TTTGAGCGTATTCTCTACGTGG	HDAC8	ENSG00000147099	0.82859146248906	[182,136]	[51,249]	6	hSpCas9	negative selection	5407987
72495205	72495227	X	-	27760321	MOLM13	viability	GGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.9317326314230437	[355,324]	[52,632]	6	hSpCas9	negative selection	5407988
72495254	72495276	X	-	27760321	MOLM13	viability	CTTACAGAGATGAAGCATCTGG	HDAC8	ENSG00000147099	1.0166704052267663	[157,183]	[7,357]	7	hSpCas9	negative selection	5407989
72568759	72568781	X	-	27760321	MOLM13	viability	ATCCGGACTCCATAGAATATGG	HDAC8	ENSG00000147099	0.45239305622036063	[134,83]	[167,10]	3	hSpCas9	negative selection	5407990
72568818	72568840	X	+	27760321	MOLM13	viability	CTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.7755390361289859	[497,401]	[207,95]	-5	hSpCas9	negative selection	5407991
72568856	72568878	X	-	27760321	MOLM13	viability	AAGCCTAAAGTGGCCTCCATGG	HDAC8	ENSG00000147099	0.41779535908577925	[488,514]	[31,676]	3	hSpCas9	negative selection	5407992
72572056	72572078	X	-	27760321	MOLM13	viability	TGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.188314232013833	[382,310]	[202,237]	1	hSpCas9	negative selection	5407993
72572087	72572109	X	+	27760321	MOLM13	viability	ATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-3.2901239881373385	[141,83]	[0,10]	-9	hSpCas9	negative selection	5407994
72572836	72572859	X	+	27661255	K562	viability	GCTCCTCTGATCGGCCGCAGCGG	HDAC8	ENSG00000147099	0.1599666798180172	[523,771]	[650,508]	5	dCas9-KRAB	negative selection	5484284
72572427	72572450	X	-	27661255	K562	viability	GTCCAATGGACAGGTAGGAGTGG	HDAC8	ENSG00000147099	0.23006448251943934	[295,276]	[251,282]	7	dCas9-KRAB	negative selection	5484285
72572432	72572455	X	-	27661255	K562	viability	GGGACGTCCAATGGACAGGTAGG	HDAC8	ENSG00000147099	0.17105739226122518	[1264,1300]	[1358,977]	6	dCas9-KRAB	negative selection	5484286
72572839	72572862	X	-	27661255	K562	viability	GCACCGCTGCGGCCGATCAGAGG	HDAC8	ENSG00000147099	-0.0894309315715632	[859,846]	[681,605]	-3	dCas9-KRAB	negative selection	5484287
72567929	72567952	X	+	27260156	BXPC3	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.35903786063629006	[1957]	[2125,2827,2587,3034]	7	hSpCas9	negative selection	5547163
72568778	72568801	X	+	27260156	BXPC3	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5553232922915603	[1189]	[1711,1694,1710,2253]	9	hSpCas9	negative selection	5547164
72567940	72567963	X	-	27260156	BXPC3	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.08290882756969764	[1139]	[970,1059,1053,1470]	-2	hSpCas9	negative selection	5547165
72568865	72568888	X	-	27260156	BXPC3	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.4758988225140923	[398]	[225,327,227,437]	-8	hSpCas9	negative selection	5611424
72572086	72572109	X	+	27260156	BXPC3	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.21019229829140065	[517]	[393,436,593,454]	-5	hSpCas9	negative selection	5611425
72572056	72572079	X	-	27260156	BXPC3	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.6375527572891873	[490]	[301,318,338,365]	-8	hSpCas9	negative selection	5611426
72567929	72567952	X	+	27260156	A673	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.2844542415206628	[1957]	[3052,2655,2784,2988]	6	hSpCas9	negative selection	5668414
72568778	72568801	X	+	27260156	A673	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.4533753853684861	[1189]	[2018,2003,1832,1973]	8	hSpCas9	negative selection	5668415
72567940	72567963	X	-	27260156	A673	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.37510220607717515	[1139]	[1977,1570,1758,1820]	8	hSpCas9	negative selection	5668416
72568865	72568888	X	-	27260156	A673	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.30293457801863644	[398]	[348,358,455,383]	-6	hSpCas9	negative selection	5732675
72572086	72572109	X	+	27260156	A673	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.13684178963811383	[517]	[818,537,671,726]	3	hSpCas9	negative selection	5732676
72572056	72572079	X	-	27260156	A673	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.23698753810767406	[490]	[639,403,501,470]	-5	hSpCas9	negative selection	5732677
72567929	72567952	X	+	27260156	A375	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.6132408467816544	[1957]	[3382,4064,3522,3130]	8	hSpCas9	negative selection	5789665
72568778	72568801	X	+	27260156	A375	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.705566574573663	[1189]	[2230,2552,2108,2210]	9	hSpCas9	negative selection	5789666
72567940	72567963	X	-	27260156	A375	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.2863230626430402	[1139]	[1686,1848,1714,1307]	4	hSpCas9	negative selection	5789667
72568865	72568888	X	-	27260156	A375	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.1615102148324354	[398]	[536,617,316,242]	-2	hSpCas9	negative selection	5853926
72572086	72572109	X	+	27260156	A375	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.13454424705059936	[517]	[533,658,680,765]	2	hSpCas9	negative selection	5853927
72572056	72572079	X	-	27260156	A375	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.14386484231377128	[490]	[410,678,452,548]	-2	hSpCas9	negative selection	5853928
72567929	72567952	X	+	27260156	COLO741	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.3447523118698763	[1957]	[3424,3157,2976]	7	hSpCas9	negative selection	5910916
72568778	72568801	X	+	27260156	COLO741	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.4763212118156359	[1189]	[1982,2494,1870]	8	hSpCas9	negative selection	5910917
72567940	72567963	X	-	27260156	COLO741	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.19019076200134033	[1139]	[2035,1457,1528]	4	hSpCas9	negative selection	5910918
72568865	72568888	X	-	27260156	COLO741	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.38048900491236903	[398]	[481,398,306]	-7	hSpCas9	negative selection	5975177
72572086	72572109	X	+	27260156	COLO741	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.23844168761809606	[517]	[702,574,425]	-5	hSpCas9	negative selection	5975178
72572056	72572079	X	-	27260156	COLO741	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.1412381945663131	[490]	[621,634,460]	-3	hSpCas9	negative selection	5975179
72567929	72567952	X	+	27260156	CAL120	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.5074594020592347	[1957]	[4331,3448,2751]	7	hSpCas9	negative selection	6032167
72568778	72568801	X	+	27260156	CAL120	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.7534357015354969	[1189]	[2543,2608,2344]	9	hSpCas9	negative selection	6032168
72567940	72567963	X	-	27260156	CAL120	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.19847199968203433	[1139]	[1800,1488,1618]	3	hSpCas9	negative selection	6032169
72568865	72568888	X	-	27260156	CAL120	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.36843738249657165	[398]	[357,481,310]	-5	hSpCas9	negative selection	6096428
72572086	72572109	X	+	27260156	CAL120	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.13834146501396116	[517]	[741,681,708]	2	hSpCas9	negative selection	6096429
72572056	72572079	X	-	27260156	CAL120	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.8671519288452976	[490]	[234,323,428]	-8	hSpCas9	negative selection	6096430
72567929	72567952	X	+	27260156	CADOES1	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.5880096344640888	[1957]	[2558,3309,2577,2494]	8	hSpCas9	negative selection	6153418
72568778	72568801	X	+	27260156	CADOES1	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.519825927879205	[1189]	[1437,1617,1650,1642]	8	hSpCas9	negative selection	6153419
72567940	72567963	X	-	27260156	CADOES1	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.041039588473295474	[1139]	[877,1199,908,1139]	0	hSpCas9	negative selection	6153420
72568865	72568888	X	-	27260156	CADOES1	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.5537786862561499	[398]	[201,321,195,292]	-7	hSpCas9	negative selection	6217679
72572086	72572109	X	+	27260156	CADOES1	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.065372892239344	[517]	[409,593,431,403]	-1	hSpCas9	negative selection	6217680
72572056	72572079	X	-	27260156	CADOES1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.02352780353454216	[490]	[531,392,475,454]	0	hSpCas9	negative selection	6217681
72567929	72567952	X	+	27260156	EWS502	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.566926970199114	[1957]	[2916,3058,3258,3062]	8	hSpCas9	negative selection	6274669
72568778	72568801	X	+	27260156	EWS502	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.8014821917250003	[1189]	[2430,1829,1949,2577]	9	hSpCas9	negative selection	6274670
72567940	72567963	X	-	27260156	EWS502	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.016637943832887414	[1139]	[1218,1030,1467,1170]	0	hSpCas9	negative selection	6274671
72568865	72568888	X	-	27260156	EWS502	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.7457921172118718	[398]	[259,306,166,269]	-8	hSpCas9	negative selection	6338930
72572086	72572109	X	+	27260156	EWS502	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.36867463073131507	[517]	[287,284,478,687]	-6	hSpCas9	negative selection	6338931
72572056	72572079	X	-	27260156	EWS502	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.854415921601863	[490]	[263,384,262,231]	-8	hSpCas9	negative selection	6338932
72567929	72567952	X	+	27260156	EW8	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.33202243992896774	[1957]	[2352,2292,1692,1737]	6	hSpCas9	negative selection	6395920
72568778	72568801	X	+	27260156	EW8	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.48876155732247395	[1189]	[1403,1535,1168,1337]	8	hSpCas9	negative selection	6395921
72567940	72567963	X	-	27260156	EW8	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.1302241225102565	[1139]	[719,726,946,947]	-2	hSpCas9	negative selection	6395922
72568865	72568888	X	-	27260156	EW8	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.9010171138805595	[398]	[149,231,154,155]	-9	hSpCas9	negative selection	6460181
72572086	72572109	X	+	27260156	EW8	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.03635694402620533	[517]	[393,341,198,733]	0	hSpCas9	negative selection	6460182
72572056	72572079	X	-	27260156	EW8	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.8715011429459318	[490]	[212,380,115,176]	-9	hSpCas9	negative selection	6460183
72567929	72567952	X	+	27260156	CORL105	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.519316848456925	[1957]	[3554,3290,3675,2690]	8	hSpCas9	negative selection	6517171
72568778	72568801	X	+	27260156	CORL105	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5793360138235084	[1189]	[2105,1778,2668,1870]	9	hSpCas9	negative selection	6517172
72567940	72567963	X	-	27260156	CORL105	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.6495529979407013	[1139]	[2357,1873,2518,1703]	9	hSpCas9	negative selection	6517173
72568865	72568888	X	-	27260156	CORL105	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.18961290184587118	[398]	[349,334,546,426]	-4	hSpCas9	negative selection	6581432
72572086	72572109	X	+	27260156	CORL105	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.32155908969858654	[517]	[649,833,840,713]	6	hSpCas9	negative selection	6581433
72572056	72572079	X	-	27260156	CORL105	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.04942598531225209	[490]	[551,542,717,584]	0	hSpCas9	negative selection	6581434
72567929	72567952	X	+	27260156	HS294T	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.6995026876242538	[1957]	[1067,1139,971,1856]	8	hSpCas9	negative selection	6638422
72568778	72568801	X	+	27260156	HS294T	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.3437117169948265	[1189]	[568,561,539,680]	4	hSpCas9	negative selection	6638423
72567940	72567963	X	-	27260156	HS294T	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.757344668818914	[1139]	[704,809,661,813]	8	hSpCas9	negative selection	6638424
72568865	72568888	X	-	27260156	HS294T	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.45402160180040874	[398]	[102,163,60,122]	-6	hSpCas9	negative selection	6702683
72572086	72572109	X	+	27260156	HS294T	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.6378657765849833	[517]	[182,291,315,498]	8	hSpCas9	negative selection	6702684
72572056	72572079	X	-	27260156	HS294T	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.6631069679608528	[490]	[105,115,136,121]	-7	hSpCas9	negative selection	6702685
72567929	72567952	X	+	27260156	HCC44	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.43075323897937645	[1957]	[3301,2461,4290,2214]	7	hSpCas9	negative selection	6759673
72568778	72568801	X	+	27260156	HCC44	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5403626427357544	[1189]	[2237,1647,2165,1869]	8	hSpCas9	negative selection	6759674
72567940	72567963	X	-	27260156	HCC44	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.02212603402162938	[1139]	[1279,1306,1304,1180]	0	hSpCas9	negative selection	6759675
72568865	72568888	X	-	27260156	HCC44	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.754760320846724	[398]	[300,178,482,160]	-8	hSpCas9	negative selection	6823934
72572086	72572109	X	+	27260156	HCC44	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.07293175803388234	[517]	[510,520,693,522]	-1	hSpCas9	negative selection	6823935
72572056	72572079	X	-	27260156	HCC44	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.4414247612883936	[490]	[592,449,401,203]	-6	hSpCas9	negative selection	6823936
72567929	72567952	X	+	27260156	G402	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.6763918968463001	[1957]	[4447,2969,4071,3809]	8	hSpCas9	negative selection	6880924
72568778	72568801	X	+	27260156	G402	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.658797726623155	[1189]	[2433,1942,2746,2048]	7	hSpCas9	negative selection	6880925
72567940	72567963	X	-	27260156	G402	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.24276845936637925	[1139]	[1250,1418,2356,1487]	3	hSpCas9	negative selection	6880926
72568865	72568888	X	-	27260156	G402	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.688518808791287	[398]	[219,214,192,549]	-7	hSpCas9	negative selection	6945185
72572086	72572109	X	+	27260156	G402	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.024640299492689255	[517]	[828,419,834,505]	0	hSpCas9	negative selection	6945186
72572056	72572079	X	-	27260156	G402	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.30277825360118615	[490]	[847,451,326,369]	-4	hSpCas9	negative selection	6945187
72567929	72567952	X	+	27260156	L33	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.21518766499054554	[1957]	[2613,977,1261,2074]	5	hSpCas9	negative selection	7002175
72568778	72568801	X	+	27260156	L33	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.46560170433090486	[1189]	[1690,687,1030,1561]	8	hSpCas9	negative selection	7002176
72567940	72567963	X	-	27260156	L33	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.29924774363363493	[1139]	[1390,617,780,1467]	6	hSpCas9	negative selection	7002177
72568865	72568888	X	-	27260156	L33	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.92622088080975	[398]	[159,91,112,275]	-9	hSpCas9	negative selection	7066436
72572086	72572109	X	+	27260156	L33	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.4196305441465785	[517]	[608,279,392,853]	8	hSpCas9	negative selection	7066437
72572056	72572079	X	-	27260156	L33	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.44188658511365386	[490]	[370,132,234,375]	-8	hSpCas9	negative selection	7066438
72567929	72567952	X	+	27260156	K562	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.6959340465940778	[1957]	[2710,2866,3392,2327]	8	hSpCas9	negative selection	7123426
72568778	72568801	X	+	27260156	K562	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.7562836995028972	[1189]	[2042,1529,1453,2073]	8	hSpCas9	negative selection	7123427
72567940	72567963	X	-	27260156	K562	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.06852509099512649	[1139]	[1034,652,1452,1072]	0	hSpCas9	negative selection	7123428
72568865	72568888	X	-	27260156	K562	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.6058602028953627	[398]	[108,185,416,207]	-6	hSpCas9	negative selection	7187687
72572086	72572109	X	+	27260156	K562	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.3572463522224392	[517]	[712,780,571,336]	4	hSpCas9	negative selection	7187688
72572056	72572079	X	-	27260156	K562	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.7049143571863976	[490]	[268,174,272,337]	-7	hSpCas9	negative selection	7187689
72567929	72567952	X	+	27260156	HT29	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.37871453338830907	[1957]	[3435,3175,2931,2872]	7	hSpCas9	negative selection	7244677
72568778	72568801	X	+	27260156	HT29	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.49799777416501856	[1189]	[2334,2287,1845,1765]	8	hSpCas9	negative selection	7244678
72567940	72567963	X	-	27260156	HT29	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.15388707011789204	[1139]	[1435,1292,1259,1029]	-3	hSpCas9	negative selection	7244679
72568865	72568888	X	-	27260156	HT29	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.36272742371354083	[398]	[432,395,350,336]	-6	hSpCas9	negative selection	7308938
72572086	72572109	X	+	27260156	HT29	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.16546515841676712	[517]	[450,687,506,593]	-3	hSpCas9	negative selection	7308939
72572056	72572079	X	-	27260156	HT29	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.5381082114484441	[490]	[363,588,388,321]	-7	hSpCas9	negative selection	7308940
72567929	72567952	X	+	27260156	MHHES1	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.41029522666051665	[1957]	[3245,3647,2872,2176]	7	hSpCas9	negative selection	7365928
72568778	72568801	X	+	27260156	MHHES1	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.37280765500465973	[1189]	[1938,1842,1666,1534]	6	hSpCas9	negative selection	7365929
72567940	72567963	X	-	27260156	MHHES1	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.30190284961205605	[1139]	[1003,1593,732,894]	-5	hSpCas9	negative selection	7365930
72568865	72568888	X	-	27260156	MHHES1	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.3648340182444235	[398]	[248,506,542,142]	-6	hSpCas9	negative selection	7430189
72572086	72572109	X	+	27260156	MHHES1	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.2946678932750045	[517]	[971,653,905,411]	5	hSpCas9	negative selection	7430190
72572056	72572079	X	-	27260156	MHHES1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-1.0152256183457544	[490]	[310,281,291,220]	-9	hSpCas9	negative selection	7430191
72567929	72567952	X	+	27260156	MEWO	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.2852534062878562	[1957]	[2535,2083,2135]	6	hSpCas9	negative selection	7487179
72568778	72568801	X	+	27260156	MEWO	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5535462320004945	[1189]	[1522,1458,1898]	9	hSpCas9	negative selection	7487180
72567940	72567963	X	-	27260156	MEWO	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.22250038108760806	[1139]	[1603,949,1249]	5	hSpCas9	negative selection	7487181
72568865	72568888	X	-	27260156	MEWO	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.01876068759143326	[398]	[395,501,211]	0	hSpCas9	negative selection	7551440
72572086	72572109	X	+	27260156	MEWO	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.035520651684302004	[517]	[568,478,388]	0	hSpCas9	negative selection	7551441
72572056	72572079	X	-	27260156	MEWO	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.3545983556275433	[490]	[554,281,278]	-6	hSpCas9	negative selection	7551442
72567929	72567952	X	+	27260156	LNCAPCLONEFGC	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.6870659980759801	[1957]	[2709,2752,3420,2629]	9	hSpCas9	negative selection	7608430
72568778	72568801	X	+	27260156	LNCAPCLONEFGC	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5328734773750343	[1189]	[1468,1520,1810,1477]	8	hSpCas9	negative selection	7608431
72567940	72567963	X	-	27260156	LNCAPCLONEFGC	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.049462790001546075	[1139]	[1057,841,1186,940]	-1	hSpCas9	negative selection	7608432
72568865	72568888	X	-	27260156	LNCAPCLONEFGC	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.7777419277271808	[398]	[242,167,248,190]	-8	hSpCas9	negative selection	7672691
72572086	72572109	X	+	27260156	LNCAPCLONEFGC	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.113779684168938	[517]	[331,417,471,520]	-2	hSpCas9	negative selection	7672692
72572056	72572079	X	-	27260156	LNCAPCLONEFGC	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-1.049655422930602	[490]	[286,146,191,232]	-9	hSpCas9	negative selection	7672693
72567929	72567952	X	+	27260156	PANC0327	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.5432679025267788	[1957]	[2576,2300,2839,2453]	7	hSpCas9	negative selection	7729681
72568778	72568801	X	+	27260156	PANC0327	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.9335960066734224	[1189]	[2533,1808,1950,1850]	9	hSpCas9	negative selection	7729682
72567940	72567963	X	-	27260156	PANC0327	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.603456182448048	[1139]	[1592,1431,1484,1661]	8	hSpCas9	negative selection	7729683
72568865	72568888	X	-	27260156	PANC0327	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.16702848403436338	[398]	[688,301,399,236]	2	hSpCas9	negative selection	7793942
72572086	72572109	X	+	27260156	PANC0327	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.32827886862893607	[517]	[598,660,677,363]	5	hSpCas9	negative selection	7793943
72572056	72572079	X	-	27260156	PANC0327	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.042662521423025984	[490]	[566,463,284,383]	0	hSpCas9	negative selection	7793944
72567929	72567952	X	+	27260156	NCIH2009	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.5101955420589035	[1957]	[4642,3268,3928]	7	hSpCas9	negative selection	7850932
72568778	72568801	X	+	27260156	NCIH2009	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.7059718141878362	[1189]	[2645,2916,2551]	8	hSpCas9	negative selection	7850933
72567940	72567963	X	-	27260156	NCIH2009	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.9761671136799877	[1139]	[3672,3481,2339]	9	hSpCas9	negative selection	7850934
72568865	72568888	X	-	27260156	NCIH2009	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.08938310792218068	[398]	[651,643,492]	1	hSpCas9	negative selection	7915193
72572086	72572109	X	+	27260156	NCIH2009	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.7361567113632632	[517]	[1362,1077,1206]	8	hSpCas9	negative selection	7915194
72572056	72572079	X	-	27260156	NCIH2009	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.06544290390287905	[490]	[835,863,472]	0	hSpCas9	negative selection	7915195
72567929	72567952	X	+	27260156	NCIH1373	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.9444784501056458	[1957]	[4645,3970,3516,1283]	8	hSpCas9	negative selection	7972183
72568778	72568801	X	+	27260156	NCIH1373	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.8405072060257472	[1189]	[2937,1922,2278,669]	8	hSpCas9	negative selection	7972184
72567940	72567963	X	-	27260156	NCIH1373	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.8909741262213158	[1139]	[2387,1668,3356,549]	8	hSpCas9	negative selection	7972185
72568865	72568888	X	-	27260156	NCIH1373	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.22979423247464845	[398]	[734,442,634,80]	2	hSpCas9	negative selection	8036444
72572086	72572109	X	+	27260156	NCIH1373	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.5573662789114	[517]	[991,690,617,308]	5	hSpCas9	negative selection	8036445
72572056	72572079	X	-	27260156	NCIH1373	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.27570483026726633	[490]	[347,355,389,192]	-3	hSpCas9	negative selection	8036446
72567929	72567952	X	+	27260156	PATU8902	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.7928764864179167	[1957]	[5086,4262,4171,5576]	8	hSpCas9	negative selection	8093434
72568778	72568801	X	+	27260156	PATU8902	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.37717394134712867	[1189]	[2068,2131,1935,2561]	4	hSpCas9	negative selection	8093435
72567940	72567963	X	-	27260156	PATU8902	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.13305422692900826	[1139]	[1662,1382,1586,1060]	-1	hSpCas9	negative selection	8093436
72568865	72568888	X	-	27260156	PATU8902	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.259321538360091	[398]	[293,844,176,635]	-3	hSpCas9	negative selection	8157695
72572086	72572109	X	+	27260156	PATU8902	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.3126730827936749	[517]	[836,1135,612,1088]	3	hSpCas9	negative selection	8157696
72572056	72572079	X	-	27260156	PATU8902	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.6234597006793821	[490]	[444,359,395,601]	-5	hSpCas9	negative selection	8157697
72567929	72567952	X	+	27260156	PANC1	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.4602198145585894	[1957]	[2060,2649,2642,1992]	7	hSpCas9	negative selection	8214685
72568778	72568801	X	+	27260156	PANC1	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.6167655726957815	[1189]	[1495,1787,1888,1183]	8	hSpCas9	negative selection	8214686
72567940	72567963	X	-	27260156	PANC1	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.5486399396422441	[1139]	[1499,1803,1209,1287]	8	hSpCas9	negative selection	8214687
72568865	72568888	X	-	27260156	PANC1	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.2942414682166051	[398]	[485,387,414,382]	5	hSpCas9	negative selection	8278946
72572086	72572109	X	+	27260156	PANC1	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.39299085368337916	[517]	[455,601,748,535]	6	hSpCas9	negative selection	8278947
72572056	72572079	X	-	27260156	PANC1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.1730173847610174	[490]	[341,558,587,432]	2	hSpCas9	negative selection	8278948
72567929	72567952	X	+	27260156	PANC0813	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.3951637436628439	[1957]	[2935,3304,3055,2800]	6	hSpCas9	negative selection	8335936
72568778	72568801	X	+	27260156	PANC0813	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5193467137511321	[1189]	[2299,1918,2187,1651]	8	hSpCas9	negative selection	8335937
72567940	72567963	X	-	27260156	PANC0813	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.1874139544437139	[1139]	[1930,1132,1652,1423]	3	hSpCas9	negative selection	8335938
72568865	72568888	X	-	27260156	PANC0813	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.7174830375477877	[398]	[382,307,220,238]	-7	hSpCas9	negative selection	8400197
72572086	72572109	X	+	27260156	PANC0813	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.21956299544549462	[517]	[729,523,981,605]	3	hSpCas9	negative selection	8400198
72572056	72572079	X	-	27260156	PANC0813	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.4279961147501971	[490]	[390,392,567,362]	-6	hSpCas9	negative selection	8400199
72567929	72567952	X	+	27260156	RDES	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.534746483141312	[1957]	[2765,2922,3348,4195]	8	hSpCas9	negative selection	8457187
72568778	72568801	X	+	27260156	RDES	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.7907192788661566	[1189]	[2015,2275,2391,2874]	9	hSpCas9	negative selection	8457188
72567940	72567963	X	-	27260156	RDES	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.17502055284430562	[1139]	[917,1127,1326,1323]	-3	hSpCas9	negative selection	8457189
72568865	72568888	X	-	27260156	RDES	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.5742298668159663	[398]	[195,315,253,510]	-7	hSpCas9	negative selection	8521448
72572086	72572109	X	+	27260156	RDES	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.03552222460096052	[517]	[613,432,636,638]	0	hSpCas9	negative selection	8521449
72572056	72572079	X	-	27260156	RDES	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.5875754013650751	[490]	[301,371,439,399]	-7	hSpCas9	negative selection	8521450
72567929	72567952	X	+	27260156	PC3	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.22028618809999134	[1957]	[1637,2035,3869,2211]	5	hSpCas9	negative selection	8578438
72568778	72568801	X	+	27260156	PC3	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5031799138337925	[1189]	[1201,1485,2437,1941]	8	hSpCas9	negative selection	8578439
72567940	72567963	X	-	27260156	PC3	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.150744679681041	[1139]	[919,1131,2203,1169]	3	hSpCas9	negative selection	8578440
72568865	72568888	X	-	27260156	PC3	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.46294097190495687	[398]	[210,264,547,231]	-8	hSpCas9	negative selection	8642699
72572086	72572109	X	+	27260156	PC3	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.06096855354524733	[517]	[259,586,972,582]	1	hSpCas9	negative selection	8642700
72572056	72572079	X	-	27260156	PC3	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.4194972923717215	[490]	[246,409,755,206]	-7	hSpCas9	negative selection	8642701
72567929	72567952	X	+	27260156	PATU8988T	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.3126052040217968	[1957]	[2111,2602,2076,2658]	5	hSpCas9	negative selection	8699689
72568778	72568801	X	+	27260156	PATU8988T	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.42628050392644323	[1189]	[1729,1248,1613,1559]	7	hSpCas9	negative selection	8699690
72567940	72567963	X	-	27260156	PATU8988T	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.42840060571483185	[1139]	[688,837,795,964]	-6	hSpCas9	negative selection	8699691
72568865	72568888	X	-	27260156	PATU8988T	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.19441718465384747	[398]	[450,286,268,336]	-3	hSpCas9	negative selection	8763950
72572086	72572109	X	+	27260156	PATU8988T	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	0.27211876804275226	[517]	[1143,370,469,395]	5	hSpCas9	negative selection	8763951
72572056	72572079	X	-	27260156	PATU8988T	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.7591552040365215	[490]	[278,245,366,219]	-8	hSpCas9	negative selection	8763952
72567929	72567952	X	+	27260156	T47D	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.36525343625092255	[1957]	[3004,2638,3034,3102]	7	hSpCas9	negative selection	8820940
72568778	72568801	X	+	27260156	T47D	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.6436908549666693	[1189]	[2199,1931,2218,2336]	9	hSpCas9	negative selection	8820941
72567940	72567963	X	-	27260156	T47D	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.20300654958340458	[1139]	[1617,1320,1598,1595]	4	hSpCas9	negative selection	8820942
72568865	72568888	X	-	27260156	T47D	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.23264694546103895	[398]	[374,321,535,351]	-5	hSpCas9	negative selection	8885201
72572086	72572109	X	+	27260156	T47D	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.08933798603973812	[517]	[569,569,572,554]	-2	hSpCas9	negative selection	8885202
72572056	72572079	X	-	27260156	T47D	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.24454034093429178	[490]	[446,428,538,520]	-5	hSpCas9	negative selection	8885203
72567929	72567952	X	+	27260156	SU8686	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.3775354440266674	[1957]	[2387,2378,2615,2760]	6	hSpCas9	negative selection	8942191
72568778	72568801	X	+	27260156	SU8686	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.2762768494407164	[1189]	[1336,1183,1518,1763]	5	hSpCas9	negative selection	8942192
72567940	72567963	X	-	27260156	SU8686	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.3533670370552222	[1139]	[825,835,873,1032]	-5	hSpCas9	negative selection	8942193
72568865	72568888	X	-	27260156	SU8686	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-1.3163488987646306	[398]	[158,148,160,167]	-9	hSpCas9	negative selection	9006452
72572086	72572109	X	+	27260156	SU8686	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.04173761220667391	[517]	[386,368,552,755]	0	hSpCas9	negative selection	9006453
72572056	72572079	X	-	27260156	SU8686	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-1.2241115559714464	[490]	[200,175,241,220]	-9	hSpCas9	negative selection	9006454
72567929	72567952	X	+	27260156	SKES1	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.35514027566034656	[1957]	[2824,2787,2272,2199]	7	hSpCas9	negative selection	9063442
72568778	72568801	X	+	27260156	SKES1	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5070805559278062	[1189]	[1610,2022,1605,1538]	8	hSpCas9	negative selection	9063443
72567940	72567963	X	-	27260156	SKES1	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.10365628817143269	[1139]	[1032,1116,1119,965]	-2	hSpCas9	negative selection	9063444
72568865	72568888	X	-	27260156	SKES1	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.6355732452466862	[398]	[289,253,227,254]	-8	hSpCas9	negative selection	9127703
72572086	72572109	X	+	27260156	SKES1	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.028001041962844517	[517]	[467,546,485,518]	0	hSpCas9	negative selection	9127704
72572056	72572079	X	-	27260156	SKES1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.7145431891840799	[490]	[345,425,198,248]	-9	hSpCas9	negative selection	9127705
72567929	72567952	X	+	27260156	TOV112D	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.41432507570125443	[1957]	[3271,2847,2316,2138]	7	hSpCas9	negative selection	9184693
72568778	72568801	X	+	27260156	TOV112D	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.4349984995086622	[1189]	[1446,2198,1344,1582]	7	hSpCas9	negative selection	9184694
72567940	72567963	X	-	27260156	TOV112D	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.2686670748275575	[1139]	[1195,1738,1118,1515]	5	hSpCas9	negative selection	9184695
72568865	72568888	X	-	27260156	TOV112D	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	0.0733482572658162	[398]	[617,412,463,206]	1	hSpCas9	negative selection	9248954
72572086	72572109	X	+	27260156	TOV112D	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.00023231461923631236	[517]	[598,582,482,433]	0	hSpCas9	negative selection	9248955
72572056	72572079	X	-	27260156	TOV112D	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.11191380361351075	[490]	[417,962,363,477]	2	hSpCas9	negative selection	9248956
72567929	72567952	X	+	27260156	TC71	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.29496173852685326	[1957]	[2282,2458,2628,2956]	7	hSpCas9	negative selection	9305944
72568778	72568801	X	+	27260156	TC71	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.5178281744761453	[1189]	[1786,1836,1749,1941]	9	hSpCas9	negative selection	9305945
72567940	72567963	X	-	27260156	TC71	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	0.14384092474926646	[1139]	[1348,1409,1315,1324]	3	hSpCas9	negative selection	9305946
72568865	72568888	X	-	27260156	TC71	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.4237889529664609	[398]	[281,419,258,316]	-8	hSpCas9	negative selection	9370205
72572086	72572109	X	+	27260156	TC71	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.056094692525188825	[517]	[660,546,564,347]	-1	hSpCas9	negative selection	9370206
72572056	72572079	X	-	27260156	TC71	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.46973967205519634	[490]	[391,415,317,396]	-8	hSpCas9	negative selection	9370207
72567929	72567952	X	+	27260156	TC32	viability	CTTTGCACATTCCGTCAATCAGG	HDAC8	ENSG00000147099	0.4126041948527308	[1957]	[2292,1917,3102,2681]	7	hSpCas9	negative selection	9427195
72568778	72568801	X	+	27260156	TC32	viability	GATGATCATCATCGCCCTCTTGG	HDAC8	ENSG00000147099	0.44828388735031877	[1189]	[1465,1025,2037,1784]	7	hSpCas9	negative selection	9427196
72567940	72567963	X	-	27260156	TC32	viability	GCTGCCCAATGCCTGATTGACGG	HDAC8	ENSG00000147099	-0.15587478041787683	[1139]	[781,573,1380,1319]	-3	hSpCas9	negative selection	9427197
72568865	72568888	X	-	27260156	TC32	viability	TAGGATAGTTAAGCCTAAAGTGG	HDAC8	ENSG00000147099	-0.7891203825217724	[398]	[211,162,177,321]	-9	hSpCas9	negative selection	9491456
72572086	72572109	X	+	27260156	TC32	viability	AATCAAAGAATGCACCATACTGG	HDAC8	ENSG00000147099	-0.18749736562362884	[517]	[443,283,547,484]	-3	hSpCas9	negative selection	9491457
72572056	72572079	X	-	27260156	TC32	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.7461727422601012	[490]	[337,129,399,285]	-9	hSpCas9	negative selection	9491458
72329673	72329696	X	-	27869803	HPAFII	viability after 27 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.38314840825033486	[342]	[280,196,NaN]	3	hSpCas9	negative selection	9609571
72462075	72462098	X	-	27869803	HPAFII	viability after 27 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.8547751464393107	[507]	[698,302,NaN]	7	hSpCas9	negative selection	9609572
72464622	72464645	X	-	27869803	HPAFII	viability after 27 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.7709669431891681	[328]	[168,44,NaN]	-5	hSpCas9	negative selection	9609573
72495155	72495178	X	-	27869803	HPAFII	viability after 27 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.5948352605679741	[285]	[231,222,NaN]	5	hSpCas9	negative selection	9609575
72567974	72567997	X	-	27869803	HPAFII	viability after 27 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-1.4847770031376768	[602]	[73,145,NaN]	-7	hSpCas9	negative selection	9609578
72567975	72567998	X	-	27869803	HPAFII	viability after 27 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-1.185048400735202	[183]	[71,17,NaN]	-7	hSpCas9	negative selection	9609579
72329673	72329696	X	-	27869803	HPAFII	viability after 15 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.061698960502480915	[342]	[523,246,NaN]	0	hSpCas9	negative selection	9692020
72462075	72462098	X	-	27869803	HPAFII	viability after 15 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.5983939836614387	[507]	[1219,581,NaN]	6	hSpCas9	negative selection	9692021
72464622	72464645	X	-	27869803	HPAFII	viability after 15 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-1.2087634691836624	[328]	[242,96,NaN]	-8	hSpCas9	negative selection	9692022
72495155	72495178	X	-	27869803	HPAFII	viability after 15 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.40801109778655875	[285]	[643,260,NaN]	5	hSpCas9	negative selection	9692024
72567974	72567997	X	-	27869803	HPAFII	viability after 15 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-1.4899176287047309	[602]	[210,242,NaN]	-8	hSpCas9	negative selection	9692027
72567975	72567998	X	-	27869803	HPAFII	viability after 15 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.8066581825029097	[183]	[162,81,NaN]	-7	hSpCas9	negative selection	9692028
72329673	72329696	X	-	27869803	ASPC1	viability after 36 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.6021065919487592	[683]	[501,288,318]	6	hSpCas9	negative selection	9774469
72462075	72462098	X	-	27869803	ASPC1	viability after 36 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	-0.6811123726033528	[1510]	[390,401,223]	-6	hSpCas9	negative selection	9774470
72464622	72464645	X	-	27869803	ASPC1	viability after 36 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	0.715208870652521	[498]	[647,130,151]	7	hSpCas9	negative selection	9774471
72495155	72495178	X	-	27869803	ASPC1	viability after 36 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	1.1102920918281234	[614]	[557,192,606]	9	hSpCas9	negative selection	9774473
72567974	72567997	X	-	27869803	ASPC1	viability after 36 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	0.7208350609450288	[1244]	[452,1226,487]	7	hSpCas9	negative selection	9774476
72567975	72567998	X	-	27869803	ASPC1	viability after 36 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.23318389919327387	[424]	[152,114,114]	-2	hSpCas9	negative selection	9774477
72329673	72329696	X	-	27869803	PATU8988S	viability after 35 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.22015617089142697	[722]	[423,253,NaN]	2	hSpCas9	negative selection	9856918
72462075	72462098	X	-	27869803	PATU8988S	viability after 35 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.14720869066967524	[1209]	[617,460,NaN]	1	hSpCas9	negative selection	9856919
72464622	72464645	X	-	27869803	PATU8988S	viability after 35 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.5606344020781724	[580]	[224,91,NaN]	-5	hSpCas9	negative selection	9856920
72495155	72495178	X	-	27869803	PATU8988S	viability after 35 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-1.330284179961151	[689]	[117,102,NaN]	-8	hSpCas9	negative selection	9856922
72567974	72567997	X	-	27869803	PATU8988S	viability after 35 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.917990701412099	[1066]	[198,255,NaN]	-7	hSpCas9	negative selection	9856925
72567975	72567998	X	-	27869803	PATU8988S	viability after 35 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-1.117258869045239	[373]	[40,97,NaN]	-8	hSpCas9	negative selection	9856926
72329673	72329696	X	-	27869803	PATU8988S	viability after 31 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.5177799284312744	[722]	[181,225,NaN]	-5	hSpCas9	negative selection	9939367
72462075	72462098	X	-	27869803	PATU8988S	viability after 31 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	-0.16945217530917245	[1209]	[483,358,NaN]	-2	hSpCas9	negative selection	9939368
72464622	72464645	X	-	27869803	PATU8988S	viability after 31 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.5172084628258823	[580]	[127,204,NaN]	-5	hSpCas9	negative selection	9939369
72495155	72495178	X	-	27869803	PATU8988S	viability after 31 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	-0.8662740680132015	[689]	[186,104,NaN]	-7	hSpCas9	negative selection	9939371
72567974	72567997	X	-	27869803	PATU8988S	viability after 31 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-0.4857678421681745	[1066]	[243,379,NaN]	-5	hSpCas9	negative selection	9939374
72567975	72567998	X	-	27869803	PATU8988S	viability after 31 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-1.3736576652666852	[373]	[13,112,NaN]	-8	hSpCas9	negative selection	9939375
72329673	72329696	X	-	27869803	HPAFII	viability after 35 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	-0.47569813541009864	[342]	[98,153,NaN]	-3	hSpCas9	negative selection	10021816
72462075	72462098	X	-	27869803	HPAFII	viability after 35 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.8718486177272036	[507]	[670,244,NaN]	6	hSpCas9	negative selection	10021817
72464622	72464645	X	-	27869803	HPAFII	viability after 35 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-1.243259174691754	[328]	[75,63,NaN]	-6	hSpCas9	negative selection	10021818
72495155	72495178	X	-	27869803	HPAFII	viability after 35 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.7781369983434078	[285]	[252,242,NaN]	5	hSpCas9	negative selection	10021820
72567974	72567997	X	-	27869803	HPAFII	viability after 35 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-1.7214657582091424	[602]	[53,135,NaN]	-7	hSpCas9	negative selection	10021823
72567975	72567998	X	-	27869803	HPAFII	viability after 35 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.15712048583649263	[183]	[99,64,NaN]	-1	hSpCas9	negative selection	10021824
72329673	72329696	X	-	27869803	HPAFII	viability after 31 days	CAGTCACCAGTTTGTAGGGCAGG	HDAC8	ENSG00000147099	0.12235878811620632	[342]	[187,232,NaN]	0	hSpCas9	negative selection	10104265
72462075	72462098	X	-	27869803	HPAFII	viability after 31 days	AGGCTATAACCTTGCCAACACGG	HDAC8	ENSG00000147099	0.8713482704645139	[507]	[678,349,NaN]	6	hSpCas9	negative selection	10104266
72464622	72464645	X	-	27869803	HPAFII	viability after 31 days	CTCCTTTAACATGACTCCAGTGG	HDAC8	ENSG00000147099	-0.5623761496890836	[328]	[203,38,NaN]	-4	hSpCas9	negative selection	10104267
72495155	72495178	X	-	27869803	HPAFII	viability after 31 days	TTGGATCTGCACCATGGAGATGG	HDAC8	ENSG00000147099	0.7918477221905995	[285]	[319,231,NaN]	6	hSpCas9	negative selection	10104269
72567974	72567997	X	-	27869803	HPAFII	viability after 31 days	CTATGCAGCAGCTATAGGAGGGG	HDAC8	ENSG00000147099	-1.7354807501079432	[602]	[70,134,NaN]	-7	hSpCas9	negative selection	10104272
72567975	72567998	X	-	27869803	HPAFII	viability after 31 days	ACTATGCAGCAGCTATAGGAGGG	HDAC8	ENSG00000147099	-0.6057619752210491	[183]	[86,46,NaN]	-4	hSpCas9	negative selection	10104273
72572746	72572769	X	-	28162770	P31FUJ	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.61328511213194	[83]	[150]	7	hSpCas9	negative selection	10167948
72495205	72495228	X	-	28162770	P31FUJ	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.7138682931794949	[123]	[238]	7	hSpCas9	negative selection	10167949
72572730	72572753	X	-	28162770	P31FUJ	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-1.2328022044143783	[1]	[0]	-7	hSpCas9	negative selection	10167950
72572651	72572674	X	+	28162770	P31FUJ	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	1.4776911783906364	[32]	[107]	9	hSpCas9	negative selection	10167951
72572721	72572744	X	+	28162770	P31FUJ	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.22631817084417982	[443]	[445]	-2	hSpCas9	negative selection	10167952
72572695	72572718	X	+	28162770	P31FUJ	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-0.07629771873438793	[191]	[213]	0	hSpCas9	negative selection	10167953
72572056	72572079	X	-	28162770	P31FUJ	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.9389363673998652	[264]	[596]	9	hSpCas9	negative selection	10167954
72572676	72572699	X	+	28162770	P31FUJ	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	0.1122379504127533	[321]	[408]	1	hSpCas9	negative selection	10167955
72568817	72568840	X	+	28162770	P31FUJ	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.6507883034703108	[257]	[475]	7	hSpCas9	negative selection	10167956
72567907	72567930	X	-	28162770	P31FUJ	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	1.0847072192059788	[326]	[814]	9	hSpCas9	negative selection	10167957
72572746	72572769	X	-	28162770	TF1	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10337314
72495205	72495228	X	-	28162770	TF1	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10337315
72572730	72572753	X	-	28162770	TF1	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10337316
72572651	72572674	X	+	28162770	TF1	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10337317
72572721	72572744	X	+	28162770	TF1	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	NaN	[NaN]	[357]	1	hSpCas9	negative selection	10337318
72572695	72572718	X	+	28162770	TF1	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10337319
72572056	72572079	X	-	28162770	TF1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	NaN	[NaN]	[410]	1	hSpCas9	negative selection	10337320
72572676	72572699	X	+	28162770	TF1	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10337321
72568817	72568840	X	+	28162770	TF1	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	NaN	[NaN]	[280]	1	hSpCas9	negative selection	10337322
72567907	72567930	X	-	28162770	TF1	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	NaN	[NaN]	[291]	1	hSpCas9	negative selection	10337323
72572746	72572769	X	-	28162770	SKM1	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-0.0850361038557994	[17]	[29]	0	hSpCas9	negative selection	10506680
72495205	72495228	X	-	28162770	SKM1	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	2.1588894790302895	[18]	[149]	9	hSpCas9	negative selection	10506681
72572730	72572753	X	-	28162770	SKM1	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10506682
72572651	72572674	X	+	28162770	SKM1	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	1.1373563174806485	[8]	[34]	9	hSpCas9	negative selection	10506683
72572721	72572744	X	+	28162770	SKM1	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	0.16043993059368988	[123]	[244]	1	hSpCas9	negative selection	10506684
72572695	72572718	X	+	28162770	SKM1	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	0.4136265504711364	[30]	[72]	4	hSpCas9	negative selection	10506685
72572056	72572079	X	-	28162770	SKM1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.553805587072433	[92]	[111]	-4	hSpCas9	negative selection	10506686
72572676	72572699	X	+	28162770	SKM1	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.31752911516121735	[85]	[121]	-3	hSpCas9	negative selection	10506687
72568817	72568840	X	+	28162770	SKM1	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.697372461071574	[59]	[171]	6	hSpCas9	negative selection	10506688
72567907	72567930	X	-	28162770	SKM1	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-0.35937474022490135	[81]	[112]	-3	hSpCas9	negative selection	10506689
72572746	72572769	X	-	28162770	SKM1	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-0.0850361038557994	[17]	[29]	0	hSpCas9	negative selection	10676046
72495205	72495228	X	-	28162770	SKM1	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	2.1588894790302895	[18]	[149]	9	hSpCas9	negative selection	10676047
72572730	72572753	X	-	28162770	SKM1	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10676048
72572651	72572674	X	+	28162770	SKM1	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	1.1373563174806485	[8]	[34]	9	hSpCas9	negative selection	10676049
72572721	72572744	X	+	28162770	SKM1	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	0.16043993059368988	[123]	[244]	1	hSpCas9	negative selection	10676050
72572695	72572718	X	+	28162770	SKM1	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	0.4136265504711364	[30]	[72]	4	hSpCas9	negative selection	10676051
72572056	72572079	X	-	28162770	SKM1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.553805587072433	[92]	[111]	-4	hSpCas9	negative selection	10676052
72572676	72572699	X	+	28162770	SKM1	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.31752911516121735	[85]	[121]	-3	hSpCas9	negative selection	10676053
72568817	72568840	X	+	28162770	SKM1	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.697372461071574	[59]	[171]	6	hSpCas9	negative selection	10676054
72567907	72567930	X	-	28162770	SKM1	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-0.35937474022490135	[81]	[112]	-3	hSpCas9	negative selection	10676055
72572746	72572769	X	-	28162770	PL21	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.1297502865979221	[83]	[39]	1	hSpCas9	negative selection	10845412
72495205	72495228	X	-	28162770	PL21	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.6151771137681638	[122]	[81]	5	hSpCas9	negative selection	10845413
72572730	72572753	X	-	28162770	PL21	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10845414
72572651	72572674	X	+	28162770	PL21	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	0.32567049657317915	[21]	[11]	3	hSpCas9	negative selection	10845415
72572721	72572744	X	+	28162770	PL21	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.5061291824539695	[495]	[151]	-4	hSpCas9	negative selection	10845416
72572695	72572718	X	+	28162770	PL21	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-1.3605753399851588	[117]	[19]	-7	hSpCas9	negative selection	10845417
72572056	72572079	X	-	28162770	PL21	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.384822886231836	[278]	[92]	-3	hSpCas9	negative selection	10845418
72572676	72572699	X	+	28162770	PL21	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.942818339352723	[317]	[71]	-6	hSpCas9	negative selection	10845419
72568817	72568840	X	+	28162770	PL21	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-1.6208902444653603	[211]	[29]	-8	hSpCas9	negative selection	10845420
72567907	72567930	X	-	28162770	PL21	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.2592920041479774	[219]	[39]	-7	hSpCas9	negative selection	10845421
72572746	72572769	X	-	28162770	P31FUJ	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.61328511213194	[83]	[150]	7	hSpCas9	negative selection	11014778
72495205	72495228	X	-	28162770	P31FUJ	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.7138682931794949	[123]	[238]	7	hSpCas9	negative selection	11014779
72572730	72572753	X	-	28162770	P31FUJ	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-1.2328022044143783	[1]	[0]	-7	hSpCas9	negative selection	11014780
72572651	72572674	X	+	28162770	P31FUJ	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	1.4776911783906364	[32]	[107]	9	hSpCas9	negative selection	11014781
72572721	72572744	X	+	28162770	P31FUJ	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.22631817084417982	[443]	[445]	-2	hSpCas9	negative selection	11014782
72572695	72572718	X	+	28162770	P31FUJ	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-0.07629771873438793	[191]	[213]	0	hSpCas9	negative selection	11014783
72572056	72572079	X	-	28162770	P31FUJ	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.9389363673998652	[264]	[596]	9	hSpCas9	negative selection	11014784
72572676	72572699	X	+	28162770	P31FUJ	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	0.1122379504127533	[321]	[408]	1	hSpCas9	negative selection	11014785
72568817	72568840	X	+	28162770	P31FUJ	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.6507883034703108	[257]	[475]	7	hSpCas9	negative selection	11014786
72567907	72567930	X	-	28162770	P31FUJ	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	1.0847072192059788	[326]	[814]	9	hSpCas9	negative selection	11014787
72572746	72572769	X	-	28162770	OCIAML5	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-0.5807645490466022	[28]	[34]	-4	hSpCas9	negative selection	11184144
72495205	72495228	X	-	28162770	OCIAML5	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.7139128264895864	[50]	[150]	6	hSpCas9	negative selection	11184145
72572730	72572753	X	-	28162770	OCIAML5	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11184146
72572651	72572674	X	+	28162770	OCIAML5	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-3.4370290715851537	[5]	[0]	-9	hSpCas9	negative selection	11184147
72572721	72572744	X	+	28162770	OCIAML5	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.8771575518268275	[289]	[284]	-5	hSpCas9	negative selection	11184148
72572695	72572718	X	+	28162770	OCIAML5	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-1.9803906678395364	[93]	[42]	-8	hSpCas9	negative selection	11184149
72572056	72572079	X	-	28162770	OCIAML5	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.17116573537371976	[153]	[312]	1	hSpCas9	negative selection	11184150
72572676	72572699	X	+	28162770	OCIAML5	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-1.822009337007817	[189]	[96]	-7	hSpCas9	negative selection	11184151
72568817	72568840	X	+	28162770	OCIAML5	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-1.2087600839120358	[104]	[81]	-6	hSpCas9	negative selection	11184152
72567907	72567930	X	-	28162770	OCIAML5	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.0113744649322802	[219]	[196]	-6	hSpCas9	negative selection	11184153
72572746	72572769	X	-	28162770	EOL1	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-1.7422088203142692	[126]	[19]	-8	hSpCas9	negative selection	11353510
72495205	72495228	X	-	28162770	EOL1	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.44800639638679596	[144]	[55]	-3	hSpCas9	negative selection	11353511
72572730	72572753	X	-	28162770	EOL1	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-1.0754522284294659	[3]	[0]	-6	hSpCas9	negative selection	11353512
72572651	72572674	X	+	28162770	EOL1	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-0.9234491349844154	[53]	[14]	-6	hSpCas9	negative selection	11353513
72572721	72572744	X	+	28162770	EOL1	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.3218559597191384	[827]	[348]	-2	hSpCas9	negative selection	11353514
72572695	72572718	X	+	28162770	EOL1	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-1.0754522284294654	[295]	[73]	-6	hSpCas9	negative selection	11353515
72572056	72572079	X	-	28162770	EOL1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.29524573183864317	[412]	[266]	2	hSpCas9	negative selection	11353516
72572676	72572699	X	+	28162770	EOL1	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.5919059512203318	[328]	[114]	-4	hSpCas9	negative selection	11353517
72568817	72568840	X	+	28162770	EOL1	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-0.6964839838581434	[242]	[78]	-5	hSpCas9	negative selection	11353518
72567907	72567930	X	-	28162770	EOL1	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	0.09076472423528534	[302]	[169]	0	hSpCas9	negative selection	11353519
72572746	72572769	X	-	28162770	MOLM13	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-2.3047001223523482	[81]	[11]	-8	hSpCas9	negative selection	11522876
72495205	72495228	X	-	28162770	MOLM13	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.2209089301611175	[215]	[133]	-1	hSpCas9	negative selection	11522877
72572730	72572753	X	-	28162770	MOLM13	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	5.9597424778742525	[0]	[44]	10	hSpCas9	negative selection	11522878
72572651	72572674	X	+	28162770	MOLM13	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-0.25457664292651216	[32]	[19]	-1	hSpCas9	negative selection	11522879
72572721	72572744	X	+	28162770	MOLM13	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.4128116900830766	[695]	[377]	-2	hSpCas9	negative selection	11522880
72572695	72572718	X	+	28162770	MOLM13	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-3.0586564329512553	[241]	[20]	-8	hSpCas9	negative selection	11522881
72572056	72572079	X	-	28162770	MOLM13	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.5679365583949088	[375]	[402]	4	hSpCas9	negative selection	11522882
72572676	72572699	X	+	28162770	MOLM13	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-3.29339589181704	[677]	[49]	-8	hSpCas9	negative selection	11522883
72568817	72568840	X	+	28162770	MOLM13	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-1.806144023238472	[236]	[48]	-7	hSpCas9	negative selection	11522884
72567907	72567930	X	-	28162770	MOLM13	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.768603236836723	[376]	[79]	-7	hSpCas9	negative selection	11522885
72572746	72572769	X	-	28162770	HEL	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	0.02606747155186251	[91]	[59]	0	hSpCas9	negative selection	11692242
72495205	72495228	X	-	28162770	HEL	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.4612121320385514	[186]	[86]	-3	hSpCas9	negative selection	11692243
72572730	72572753	X	-	28162770	HEL	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-1.942223668720799	[5]	[0]	-8	hSpCas9	negative selection	11692244
72572651	72572674	X	+	28162770	HEL	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	1.1688076436679449	[24]	[35]	8	hSpCas9	negative selection	11692245
72572721	72572744	X	+	28162770	HEL	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	0.7922778854939261	[585]	[649]	7	hSpCas9	negative selection	11692246
72572695	72572718	X	+	28162770	HEL	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	1.34135811451708	[182]	[296]	9	hSpCas9	negative selection	11692247
72572056	72572079	X	-	28162770	HEL	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.16369209279973984	[360]	[258]	1	hSpCas9	negative selection	11692248
72572676	72572699	X	+	28162770	HEL	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.8512947025205185	[537]	[190]	-5	hSpCas9	negative selection	11692249
72568817	72568840	X	+	28162770	HEL	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	0.863128900425657	[205]	[239]	7	hSpCas9	negative selection	11692250
72567907	72567930	X	-	28162770	HEL	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	0.5800030766523943	[328]	[314]	5	hSpCas9	negative selection	11692251
72572746	72572769	X	-	28162770	MV411	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-1.223192274459386	[96]	[34]	-7	hSpCas9	negative selection	11861608
72495205	72495228	X	-	28162770	MV411	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.681334077312935	[113]	[153]	6	hSpCas9	negative selection	11861609
72572730	72572753	X	-	28162770	MV411	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11861610
72572651	72572674	X	+	28162770	MV411	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-4.211994067854522	[21]	[0]	-9	hSpCas9	negative selection	11861611
72572721	72572744	X	+	28162770	MV411	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.12616067464939573	[468]	[361]	-1	hSpCas9	negative selection	11861612
72572695	72572718	X	+	28162770	MV411	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-1.4804829037804237	[158]	[47]	-7	hSpCas9	negative selection	11861613
72572056	72572079	X	-	28162770	MV411	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	0.03384207768348638	[217]	[187]	0	hSpCas9	negative selection	11861614
72572676	72572699	X	+	28162770	MV411	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-0.8186516396749972	[200]	[95]	-5	hSpCas9	negative selection	11861615
72568817	72568840	X	+	28162770	MV411	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-1.0245220848305023	[226]	[93]	-6	hSpCas9	negative selection	11861616
72567907	72567930	X	-	28162770	MV411	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.0867168464378465	[236]	[93]	-6	hSpCas9	negative selection	11861617
72572746	72572769	X	-	28162770	MONOMAC1	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-0.07150596497569484	[43]	[47]	0	hSpCas9	negative selection	12030974
72495205	72495228	X	-	28162770	MONOMAC1	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	-0.7170439059399402	[75]	[52]	-5	hSpCas9	negative selection	12030975
72572730	72572753	X	-	28162770	MONOMAC1	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-1.1970368470595538	[1]	[0]	-7	hSpCas9	negative selection	12030976
72572651	72572674	X	+	28162770	MONOMAC1	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-2.897476565200646	[25]	[3]	-9	hSpCas9	negative selection	12030977
72572721	72572744	X	+	28162770	MONOMAC1	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.5430327019087461	[271]	[213]	-4	hSpCas9	negative selection	12030978
72572695	72572718	X	+	28162770	MONOMAC1	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-1.633900708791576	[110]	[40]	-8	hSpCas9	negative selection	12030979
72572056	72572079	X	-	28162770	MONOMAC1	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.3834499712904351	[131]	[115]	-3	hSpCas9	negative selection	12030980
72572676	72572699	X	+	28162770	MONOMAC1	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-2.0576337903941373	[206]	[56]	-9	hSpCas9	negative selection	12030981
72568817	72568840	X	+	28162770	MONOMAC1	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-2.43582370664667	[117]	[24]	-9	hSpCas9	negative selection	12030982
72567907	72567930	X	-	28162770	MONOMAC1	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.9293410638558968	[102]	[30]	-8	hSpCas9	negative selection	12030983
72572746	72572769	X	-	28162770	OCIAML2	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-1.2689959640725106	[9]	[22]	-7	hSpCas9	negative selection	12200340
72495205	72495228	X	-	28162770	OCIAML2	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	1.37854527251007	[16]	[244]	9	hSpCas9	negative selection	12200341
72572730	72572753	X	-	28162770	OCIAML2	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12200342
72572651	72572674	X	+	28162770	OCIAML2	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-1.5961607073260202	[5]	[10]	-7	hSpCas9	negative selection	12200343
72572721	72572744	X	+	28162770	OCIAML2	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-0.29831427637485475	[66]	[301]	-2	hSpCas9	negative selection	12200344
72572695	72572718	X	+	28162770	OCIAML2	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-1.8758863037284197	[48]	[73]	-8	hSpCas9	negative selection	12200345
72572056	72572079	X	-	28162770	OCIAML2	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-0.23264054885469476	[45]	[216]	-2	hSpCas9	negative selection	12200346
72572676	72572699	X	+	28162770	OCIAML2	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-2.0252186769197986	[46]	[63]	-8	hSpCas9	negative selection	12200347
72568817	72568840	X	+	28162770	OCIAML2	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-1.8383616097426485	[39]	[61]	-8	hSpCas9	negative selection	12200348
72567907	72567930	X	-	28162770	OCIAML2	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.2267042423560717	[37]	[89]	-7	hSpCas9	negative selection	12200349
72572746	72572769	X	-	28162770	OCIAML3	viability	GCGGAAGATGGAGGAGCCGGAGG	HDAC8	ENSG00000147099	-0.6398113299372881	[15]	[30]	-5	hSpCas9	negative selection	12369706
72495205	72495228	X	-	28162770	OCIAML3	viability	TGGGAATATTACGATTGCGACGG	HDAC8	ENSG00000147099	0.7134208848680841	[19]	[98]	6	hSpCas9	negative selection	12369707
72572730	72572753	X	-	28162770	OCIAML3	viability	CCGGAGGAACCGGCGGACAGTGG	HDAC8	ENSG00000147099	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12369708
72572651	72572674	X	+	28162770	OCIAML3	viability	CCGTTTGGGGATCTTGGCCAGGG	HDAC8	ENSG00000147099	-4.401362562381768	[6]	[0]	-9	hSpCas9	negative selection	12369709
72572721	72572744	X	+	28162770	OCIAML3	viability	AGCGACTGCCCACTGTCCGCCGG	HDAC8	ENSG00000147099	-1.0901167502503246	[121]	[172]	-7	hSpCas9	negative selection	12369710
72572695	72572718	X	+	28162770	OCIAML3	viability	CGGGACTATAGATATAAACCGGG	HDAC8	ENSG00000147099	-1.2355536694116867	[38]	[49]	-7	hSpCas9	negative selection	12369711
72572056	72572079	X	-	28162770	OCIAML3	viability	ATGCACTGCATAAGCAGATGAGG	HDAC8	ENSG00000147099	-1.631482345742826	[77]	[75]	-8	hSpCas9	negative selection	12369712
72572676	72572699	X	+	28162770	OCIAML3	viability	TCACACATACTGACATACTCGGG	HDAC8	ENSG00000147099	-2.0214288640588394	[77]	[57]	-8	hSpCas9	negative selection	12369713
72568817	72568840	X	+	28162770	OCIAML3	viability	GCTGCAGATAAGCATCAGTGTGG	HDAC8	ENSG00000147099	-2.285885344961831	[41]	[25]	-9	hSpCas9	negative selection	12369714
72567907	72567930	X	-	28162770	OCIAML3	viability	GTAGCAATTAACTGGTCTGGAGG	HDAC8	ENSG00000147099	-1.499370766186088	[58]	[62]	-7	hSpCas9	negative selection	12369715